-- dump date 20140619_130533 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_094056.1 52840257 3079798 654..2012 1 NC_002942.5 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 2012 dnaA 3079798 dnaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome replication initiator DnaA YP_094056.1 654 D 272624 CDS YP_094057.1 52840258 3079233 2026..3129 1 NC_002942.5 DNA polymerase III beta chain 3129 3079233 lpg0002 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III beta chain YP_094057.1 2026 D 272624 CDS YP_094058.1 52840259 3078045 3126..4187 1 NC_002942.5 DNA recombination and repair protein ATPase RecF 4187 3078045 lpg0003 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA recombination and repair protein ATPase RecF YP_094058.1 3126 D 272624 CDS YP_094059.1 52840260 3080113 4482..6902 1 NC_002942.5 DNA gyrase subunit B 6902 gyrB 3080113 gyrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA gyrase subunit B YP_094059.1 4482 D 272624 CDS YP_094060.1 52840261 3079357 complement(7271..8317) 1 NC_002942.5 peptidylarginine deiminase 8317 3079357 lpg0005 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidylarginine deiminase YP_094060.1 7271 R 272624 CDS YP_094061.1 52840262 3077938 complement(8314..10206) 1 NC_002942.5 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 10206 speA 3077938 speA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine decarboxylase YP_094061.1 8314 R 272624 CDS YP_094062.1 52840263 3079160 complement(10226..11083) 1 NC_002942.5 hydrolase 11083 3079160 lpg0007 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrolase YP_094062.1 10226 R 272624 CDS YP_094063.1 52840264 3079215 complement(11612..12871) 1 NC_002942.5 hypothetical protein 12871 3079215 lpg0008 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094063.1 11612 R 272624 CDS YP_094064.1 52840265 3079251 13059..13316 1 NC_002942.5 host factor-I protein for bacteriophage Q beta replication 13316 hfq 3079251 hfq Legionella pneumophila subsp. pneumophila str. Philadelphia 1 host factor-I protein for bacteriophage Q beta replication YP_094064.1 13059 D 272624 CDS YP_094065.1 52840266 3079468 13329..14588 1 NC_002942.5 GTP binding protein HflX 14588 3079468 lpg0010 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP binding protein HflX YP_094065.1 13329 D 272624 CDS YP_094066.1 52840267 3079124 complement(14693..15163) 1 NC_002942.5 thiol-disulfide oxidoreductase 15163 resA 3079124 resA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiol-disulfide oxidoreductase YP_094066.1 14693 R 272624 CDS YP_094067.1 52840268 3080429 complement(15332..16909) 1 NC_002942.5 hypothetical protein 16909 3080429 lpg0012 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094067.1 15332 R 272624 CDS YP_094068.1 52840269 3079474 17043..17894 1 NC_002942.5 pirin 17894 3079474 lpg0013 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pirin YP_094068.1 17043 D 272624 CDS YP_094069.1 52840270 3080548 18331..19542 1 NC_002942.5 transmembrane protein 19542 3080548 lpg0014 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094069.1 18331 D 272624 CDS YP_094070.1 52840271 3078336 19643..20716 1 NC_002942.5 multidrug resistance protein 20716 3078336 lpg0015 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance protein YP_094070.1 19643 D 272624 CDS YP_094071.1 52840272 3080493 20676..21623 1 NC_002942.5 hypothetical protein 21623 3080493 lpg0016 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094071.1 20676 D 272624 CDS YP_094072.1 52840273 3079330 21596..22513 1 NC_002942.5 hypothetical protein 22513 3079330 lpg0017 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094072.1 21596 D 272624 CDS YP_094073.1 52840274 3080039 22497..23882 1 NC_002942.5 outer membrane efflux protein 23882 3080039 lpg0018 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane efflux protein YP_094073.1 22497 D 272624 CDS YP_094074.1 52840275 3079073 24111..25793 1 NC_002942.5 hemagglutinin/protease, zinc metalloprotease 25793 3079073 lpg0019 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hemagglutinin/protease, zinc metalloprotease YP_094074.1 24111 D 272624 CDS YP_094075.1 52840276 3078378 26016..26927 1 NC_002942.5 hypothetical protein 26927 3078378 lpg0020 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094075.1 26016 D 272624 CDS YP_094076.1 52840277 3078585 27119..27598 1 NC_002942.5 hypothetical protein 27598 3078585 lpg0021 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094076.1 27119 D 272624 CDS YP_094077.1 52840278 3079385 27595..29718 1 NC_002942.5 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 29718 rlmL 3079385 rlmL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 23S rRNA m(2)G2445 methyltransferase YP_094077.1 27595 D 272624 CDS YP_094078.1 52840279 3079524 complement(29788..30330) 1 NC_002942.5 hypothetical protein 30330 3079524 lpg0023 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094078.1 29788 R 272624 CDS YP_094079.1 52840280 3078123 complement(30477..30902) 1 NC_002942.5 hemin binding protein Hbp 30902 3078123 lpg0024 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hemin binding protein Hbp YP_094079.1 30477 R 272624 CDS YP_094080.1 52840281 3079151 complement(31042..31614) 1 NC_002942.5 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 31614 pagP 3079151 pagP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 palmitoyl transferase YP_094080.1 31042 R 272624 CDS YP_094081.1 52840282 3078720 31774..33165 1 NC_002942.5 amino acid permease 33165 3078720 lpg0026 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid permease YP_094081.1 31774 D 272624 CDS YP_094082.1 52840283 3080575 complement(33175..34170) 1 NC_002942.5 low affinity inorganic phosphate transporter 34170 pit 3080575 pit Legionella pneumophila subsp. pneumophila str. Philadelphia 1 low affinity inorganic phosphate transporter YP_094082.1 33175 R 272624 CDS YP_094083.1 52840284 3078968 complement(34187..34900) 1 NC_002942.5 ubiquinone biosynthesis protein COQ7 34900 3078968 lpg0028 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinone biosynthesis protein COQ7 YP_094083.1 34187 R 272624 CDS YP_094084.1 52840285 3077881 35024..37981 1 NC_002942.5 sensory box protein 37981 rre41 3077881 rre41 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_094084.1 35024 D 272624 CDS YP_094085.1 52840286 3078767 complement(38093..39007) 1 NC_002942.5 hypothetical protein 39007 3078767 lpg0030 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094085.1 38093 R 272624 CDS YP_094086.1 52840287 3080374 38113..38232 1 NC_002942.5 hypothetical protein 38232 3080374 lpg0031 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094086.1 38113 D 272624 CDS YP_094087.1 52840288 3078295 complement(39042..40235) 1 NC_002942.5 leucine aminopeptidase 40235 3078295 lpg0032 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 leucine aminopeptidase YP_094087.1 39042 R 272624 CDS YP_094088.1 52840289 3078940 complement(40298..41323) 1 NC_002942.5 hypothetical protein 41323 3078940 lpg0033 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094088.1 40298 R 272624 CDS YP_094089.1 52840290 3079333 41587..42348 1 NC_002942.5 hypothetical protein 42348 3079333 lpg0034 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094089.1 41587 D 272624 CDS YP_094090.1 52840291 3078625 42476..42832 1 NC_002942.5 hypothetical protein 42832 3078625 lpg0035 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094090.1 42476 D 272624 CDS YP_094091.1 52840292 3080391 complement(42891..43613) 1 NC_002942.5 hypothetical protein 43613 3080391 lpg0036 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094091.1 42891 R 272624 CDS YP_094092.1 52840293 3078534 complement(43827..44570) 1 NC_002942.5 arginine ABC transporter substrate-binding protein 44570 artJ 3078534 artJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine ABC transporter substrate-binding protein YP_094092.1 43827 R 272624 CDS YP_094093.1 52840294 3079579 complement(44731..46254) 1 NC_002942.5 4921520G13 gene product; ankyrin repeat-containing protein 46254 legA10 3079579 legA10 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094093.1 44731 R 272624 CDS YP_094094.1 52840295 3079178 46638..46994 1 NC_002942.5 hypothetical protein 46994 3079178 lpg0039 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094094.1 46638 D 272624 CDS YP_094095.1 52840296 3079154 complement(47016..48011) 1 NC_002942.5 hypothetical protein 48011 3079154 lpg0040 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094095.1 47016 R 272624 CDS YP_094096.1 52840297 3079982 48185..50431 1 NC_002942.5 hypothetical protein 50431 3079982 lpg0041 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094096.1 48185 D 272624 CDS YP_094097.1 52840298 3077824 50444..51145 1 NC_002942.5 hypothetical protein 51145 3077824 lpg0042 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094097.1 50444 D 272624 CDS YP_094098.1 52840299 3079342 complement(51460..52320) 1 NC_002942.5 hypothetical protein 52320 3079342 lpg0043 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094098.1 51460 R 272624 CDS YP_094099.1 52840300 3079552 53049..53924 1 NC_002942.5 hypothetical protein 53924 3079552 lpg0044 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094099.1 53049 D 272624 CDS YP_094100.1 52840301 3078549 complement(54060..54272) 1 NC_002942.5 hypothetical protein 54272 3078549 lpg0045 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094100.1 54060 R 272624 CDS YP_094101.1 52840302 3078175 54482..54880 1 NC_002942.5 hypothetical protein 54880 3078175 lpg0046 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094101.1 54482 D 272624 CDS YP_094102.1 52840303 3078158 55046..55741 1 NC_002942.5 chloramphenicol acetyltransferase 55741 3078158 lpg0047 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chloramphenicol acetyltransferase YP_094102.1 55046 D 272624 CDS YP_094103.1 52840304 3080607 55738..56616 1 NC_002942.5 acetyltransferase 56616 3080607 lpg0048 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_094103.1 55738 D 272624 CDS YP_094104.1 52840305 3080475 56651..57964 1 NC_002942.5 amino acid transporter permease 57964 3080475 lpg0049 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid transporter permease YP_094104.1 56651 D 272624 CDS YP_094105.1 52840306 3079448 58028..58894 1 NC_002942.5 hypothetical protein 58894 3079448 lpg0050 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094105.1 58028 D 272624 CDS YP_094106.1 52840307 3079129 complement(59382..59864) 1 NC_002942.5 hypothetical protein 59864 3079129 lpg0051 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094106.1 59382 R 272624 CDS YP_094107.1 52840308 3078521 complement(60077..60970) 1 NC_002942.5 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 60970 prpB 3078521 prpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-methylisocitrate lyase YP_094107.1 60077 R 272624 CDS YP_094108.1 52840309 3080103 complement(61096..61830) 1 NC_002942.5 transferase 61830 3080103 lpg0053 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transferase YP_094108.1 61096 R 272624 CDS YP_094109.1 52840310 3080258 complement(61823..62557) 1 NC_002942.5 hypothetical protein 62557 3080258 lpg0054 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094109.1 61823 R 272624 CDS YP_094110.1 52840311 3079394 62628..63536 1 NC_002942.5 LysR family transcriptional regulator 63536 3079394 lpg0055 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094110.1 62628 D 272624 CDS YP_094111.1 52840312 3079839 63669..64400 1 NC_002942.5 hypothetical protein 64400 3079839 lpg0056 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094111.1 63669 D 272624 CDS YP_094112.1 52840313 3077880 complement(64673..65077) 1 NC_002942.5 MerR family transcriptional regulator 65077 3077880 lpg0057 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MerR family transcriptional regulator YP_094112.1 64673 R 272624 CDS YP_094113.1 52840314 3078417 65147..65890 1 NC_002942.5 hypothetical protein 65890 3078417 lpg0058 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094113.1 65147 D 272624 CDS YP_094114.1 52840315 3079731 66075..67181 1 NC_002942.5 hypothetical protein 67181 3079731 lpg0059 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094114.1 66075 D 272624 CDS YP_094115.1 52840316 3080097 68096..68767 1 NC_002942.5 methylase 68767 3080097 lpg0060 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methylase YP_094115.1 68096 D 272624 CDS YP_094116.1 52840317 3079256 68797..69975 1 NC_002942.5 multidrug resistance protein 69975 3079256 lpg0061 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance protein YP_094116.1 68797 D 272624 CDS YP_094117.1 52840318 3077901 complement(69976..71334) 1 NC_002942.5 hypothetical protein 71334 3077901 lpg0062 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094117.1 69976 R 272624 CDS YP_094118.1 52840319 3079618 71489..72676 1 NC_002942.5 phospho-2-dehydro-3-deoxyheptonate aldolase 72676 aroH 3079618 aroH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_094118.1 71489 D 272624 CDS YP_094119.1 52840320 3079078 72782..73708 1 NC_002942.5 hypothetical protein 73708 3079078 lpg0064 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094119.1 72782 D 272624 CDS YP_094120.1 52840321 3079933 73714..74535 1 NC_002942.5 hypothetical protein 74535 3079933 lpg0065 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094120.1 73714 D 272624 CDS YP_094121.1 52840322 3079847 74426..75856 1 NC_002942.5 phosphoribosylglycinamide synthetase ATP-grasp domain-containing protein 75856 3079847 lpg0066 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylglycinamide synthetase ATP-grasp domain-containing protein YP_094121.1 74426 D 272624 CDS YP_094122.1 52840323 3078018 75853..76467 1 NC_002942.5 hypothetical protein 76467 3078018 lpg0067 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094122.1 75853 D 272624 CDS YP_094123.1 52840324 3079874 76451..77398 1 NC_002942.5 transmembrane protein 77398 3079874 lpg0068 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094123.1 76451 D 272624 CDS YP_094124.1 52840325 3080072 complement(77642..78820) 1 NC_002942.5 aspartate aminotransferase 78820 aatA 3080072 aatA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartate aminotransferase YP_094124.1 77642 R 272624 CDS YP_094125.1 52840326 3077899 77828..78052 1 NC_002942.5 hypothetical protein 78052 3077899 lpg0071 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094125.1 77828 D 272624 CDS YP_094126.1 52840327 3078115 78867..80858 1 NC_002942.5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 80858 uvrB 3078115 uvrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 excinuclease ABC subunit B YP_094126.1 78867 D 272624 CDS YP_094127.1 52840328 3078840 81213..82814 1 NC_002942.5 diguanylate cyclase/phosphodiesterase 82814 3078840 lpg0073 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 diguanylate cyclase/phosphodiesterase YP_094127.1 81213 D 272624 CDS YP_094128.1 52840329 3078910 complement(82906..84477) 1 NC_002942.5 glutamate synthase 84477 3078910 lpg0074 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamate synthase YP_094128.1 82906 R 272624 CDS YP_094129.1 52840330 3078663 complement(84555..84869) 1 NC_002942.5 hypothetical protein 84869 3078663 lpg0075 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094129.1 84555 R 272624 CDS YP_094130.1 52840331 3080138 85025..85606 1 NC_002942.5 hypothetical protein 85606 3080138 lpg0076 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094130.1 85025 D 272624 CDS YP_094131.1 52840332 3077987 85693..87021 1 NC_002942.5 hypothetical protein 87021 pepP 3077987 pepP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094131.1 85693 D 272624 CDS YP_094132.1 52840333 3079604 87011..88213 1 NC_002942.5 2-octaprenyl-6-methoxyphenol hydroxylase 88213 ubiH 3079604 ubiH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-octaprenyl-6-methoxyphenol hydroxylase YP_094132.1 87011 D 272624 CDS YP_094133.1 52840334 3079598 88210..89373 1 NC_002942.5 2-polyprenyl-6-methoxyphenol 4-hydroxylase 89373 3079598 lpg0079 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_094133.1 88210 D 272624 CDS YP_094134.1 52840335 3079572 89551..90318 1 NC_002942.5 hypothetical protein 90318 3079572 lpg0080 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094134.1 89551 D 272624 CDS YP_094135.1 52840336 3079531 complement(90308..91633) 1 NC_002942.5 hypothetical protein 91633 3079531 lpg0081 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094135.1 90308 R 272624 CDS YP_094136.1 52840337 3079553 91808..92371 1 NC_002942.5 hypothetical protein 92371 3079553 lpg0082 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094136.1 91808 D 272624 CDS YP_094137.1 52840338 3079069 complement(92368..93315) 1 NC_002942.5 glutathione synthase/ribosomal protein S6 modification protein 93315 3079069 lpg0083 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione synthase/ribosomal protein S6 modification protein YP_094137.1 92368 R 272624 CDS YP_094138.1 52840339 3079389 complement(93312..94835) 1 NC_002942.5 hypothetical protein 94835 3079389 lpg0084 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094138.1 93312 R 272624 CDS YP_094139.1 52840340 3079548 complement(94825..95352) 1 NC_002942.5 hypothetical protein 95352 3079548 lpg0085 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094139.1 94825 R 272624 CDS YP_094140.1 52840341 3078545 95581..97527 1 NC_002942.5 hypothetical protein 97527 3078545 lpg0086 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094140.1 95581 D 272624 CDS YP_094141.1 52840342 3078958 complement(97493..98083) 1 NC_002942.5 hypothetical protein 98083 3078958 lpg0087 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094141.1 97493 R 272624 CDS YP_094142.1 52840343 3078501 complement(98310..99086) 1 NC_002942.5 glutamine ABC transporter 99086 3078501 lpg0088 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine ABC transporter YP_094142.1 98310 R 272624 CDS YP_094143.1 52840344 3078520 complement(99132..99578) 1 NC_002942.5 hypothetical protein 99578 3078520 lpg0089 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094143.1 99132 R 272624 CDS YP_094144.1 52840345 3078513 99689..103663 1 NC_002942.5 hypothetical protein 103663 3078513 lpg0090 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094144.1 99689 D 272624 CDS YP_094145.1 52840346 3078485 103878..104342 1 NC_002942.5 hypothetical protein 104342 3078485 lpg0091 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094145.1 103878 D 272624 CDS YP_094146.1 52840347 3078548 104748..106928 1 NC_002942.5 (exo)ribonuclease R 106928 vacB 3078548 vacB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (exo)ribonuclease R YP_094146.1 104748 D 272624 CDS YP_094147.1 52840348 3078538 106894..107670 1 NC_002942.5 tRNA/rRNA methyltransferase 107670 3078538 lpg0093 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA/rRNA methyltransferase YP_094147.1 106894 D 272624 CDS YP_094148.1 52840349 3078102 107663..108313 1 NC_002942.5 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 108313 rpiA 3078102 rpiA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribose-5-phosphate isomerase A YP_094148.1 107663 D 272624 CDS YP_094149.1 52840350 3078646 108377..109756 1 NC_002942.5 cytosolic IMP-GMP specific 5'-nucleotidase 109756 3078646 lpg0095 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytosolic IMP-GMP specific 5'-nucleotidase YP_094149.1 108377 D 272624 CDS YP_094150.1 52840351 3078855 109946..111139 1 NC_002942.5 hypothetical protein 111139 3078855 lpg0096 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094150.1 109946 D 272624 CDS YP_094151.1 52840352 3077892 111300..111641 1 NC_002942.5 alkylphosphonate uptake protein PhnA 111641 3077892 lpg0097 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkylphosphonate uptake protein PhnA YP_094151.1 111300 D 272624 CDS YP_094152.1 52840353 3078341 111756..112208 1 NC_002942.5 two component sensor and regulator, histidine kinase response regulator 112208 3078341 lpg0098 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component sensor and regulator, histidine kinase response regulator YP_094152.1 111756 D 272624 CDS YP_094153.1 52840354 3078074 complement(112238..114928) 1 NC_002942.5 DNA polymerase I 114928 polI 3078074 polI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase I YP_094153.1 112238 R 272624 CDS YP_094154.1 52840355 3079795 complement(114931..116001) 1 NC_002942.5 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 116001 3079795 lpg0100 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_094154.1 114931 R 272624 CDS YP_094155.1 52840356 3078152 116250..117032 1 NC_002942.5 hypothetical protein 117032 3078152 lpg0101 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094155.1 116250 D 272624 CDS YP_094156.1 52840357 3080015 complement(117029..118258) 1 NC_002942.5 3-oxoacyl-ACP synthase 118258 fabF 3080015 fabF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_094156.1 117029 R 272624 CDS YP_094157.1 52840358 3078747 complement(118383..119243) 1 NC_002942.5 GNAT family acetyltransferase 119243 vipF 3078747 vipF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GNAT family acetyltransferase YP_094157.1 118383 R 272624 CDS YP_094158.1 52840359 3080298 complement(119362..119937) 1 NC_002942.5 peptide methionine sulfoxide reductase 119937 3080298 lpg0104 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide methionine sulfoxide reductase YP_094158.1 119362 R 272624 CDS YP_094159.1 52840360 3079721 complement(120045..120641) 1 NC_002942.5 cytochrome oxidase-like 120641 3079721 lpg0105 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome oxidase-like YP_094159.1 120045 R 272624 CDS YP_094160.1 52840361 3079606 complement(120944..122224) 1 NC_002942.5 xanthine/uracil permease 122224 3079606 lpg0106 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 xanthine/uracil permease YP_094160.1 120944 R 272624 CDS YP_094161.1 52840362 3080137 complement(122242..123048) 1 NC_002942.5 hypothetical protein 123048 3080137 lpg0107 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094161.1 122242 R 272624 CDS YP_094162.1 52840363 3078137 122311..122415 1 NC_002942.5 hypothetical protein 122415 3078137 lpg0108 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094162.1 122311 D 272624 CDS YP_094163.1 52840364 3078015 complement(123147..123416) 1 NC_002942.5 hypothetical protein 123416 3078015 lpg0109 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094163.1 123147 R 272624 CDS YP_094164.1 52840365 3079647 124044..125846 1 NC_002942.5 hypothetical protein 125846 3079647 lpg0110 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094164.1 124044 D 272624 CDS YP_094165.1 52840366 3079138 125843..126883 1 NC_002942.5 squalene and phytoene synthases 126883 fdfT 3079138 fdfT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 squalene and phytoene synthases YP_094165.1 125843 D 272624 CDS YP_094166.1 52840367 3079620 complement(127189..130458) 1 NC_002942.5 hypothetical protein 130458 3079620 lpg0112 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094166.1 127189 R 272624 CDS YP_094167.1 52840368 3080131 complement(130773..132017) 1 NC_002942.5 hypothetical protein 132017 yuxH 3080131 yuxH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094167.1 130773 R 272624 CDS YP_094168.1 52840369 3080077 complement(132222..133676) 1 NC_002942.5 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 133676 3080077 lpg0114 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine dehydrogenase subunit 2 YP_094168.1 132222 R 272624 CDS YP_094169.1 52840370 3079475 complement(133670..133978) 1 NC_002942.5 hypothetical protein 133978 3079475 lpg0115 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094169.1 133670 R 272624 CDS YP_094170.1 52840371 3079627 complement(133978..135348) 1 NC_002942.5 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 135348 3079627 lpg0116 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine dehydrogenase subunit 1 YP_094170.1 133978 R 272624 CDS YP_094171.1 52840372 3079156 complement(135351..135728) 1 NC_002942.5 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 135728 gcvH 3079156 gcvH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine cleavage system protein H YP_094171.1 135351 R 272624 CDS YP_094172.2 229270459 3080140 complement(135762..136844) 1 NC_002942.5 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 136844 gcvT 3080140 gcvT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine cleavage system aminomethyltransferase T YP_094172.2 135762 R 272624 CDS YP_094173.1 52840374 3080144 136967..137446 1 NC_002942.5 hypothetical protein 137446 3080144 lpg0119 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094173.1 136967 D 272624 CDS YP_094174.1 52840375 3079187 complement(137421..137951) 1 NC_002942.5 IcmL-like protein 137951 3079187 lpg0120 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmL-like protein YP_094174.1 137421 R 272624 CDS YP_094175.1 52840376 3078439 138448..140187 1 NC_002942.5 ABC transporter permease 140187 3078439 lpg0121 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094175.1 138448 D 272624 CDS YP_094176.1 52840377 3079680 140195..141493 1 NC_002942.5 ABC transporter ATP-binding protein 141493 3079680 lpg0122 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094176.1 140195 D 272624 CDS YP_094177.1 52840378 3079919 complement(141570..142223) 1 NC_002942.5 thiol:disulfide interchange protein DsbA 142223 dsbA 3079919 dsbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiol:disulfide interchange protein DsbA YP_094177.1 141570 R 272624 CDS YP_094178.1 52840379 3078440 complement(142195..142797) 1 NC_002942.5 cytochrome c4 142797 3078440 lpg0124 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c4 YP_094178.1 142195 R 272624 CDS YP_094179.1 52840380 3078027 142872..143474 1 NC_002942.5 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 143474 engB 3078027 engB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosome biogenesis GTP-binding protein YsxC YP_094179.1 142872 D 272624 CDS YP_094180.1 52840381 3079450 143588..146896 1 NC_002942.5 conserved gene, eukaryotic NIN gene; hypothetical protein 146896 3079450 lpg0126 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094180.1 143588 D 272624 CDS YP_094181.1 52840382 3079611 complement(146993..148876) 1 NC_002942.5 acetyl-coenzyme A synthetase 148876 acsB 3079611 acsB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl-coenzyme A synthetase YP_094181.1 146993 R 272624 CDS YP_094182.1 52840383 3078984 complement(148878..149795) 1 NC_002942.5 3-hydroxyisobutyrate dehydrogenase 149795 3078984 lpg0128 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxyisobutyrate dehydrogenase YP_094182.1 148878 R 272624 CDS YP_094183.1 52840384 3078722 complement(149798..151324) 1 NC_002942.5 methylmalonate-semialdehyde dehydrogenase 151324 mmsA 3078722 mmsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methylmalonate-semialdehyde dehydrogenase YP_094183.1 149798 R 272624 CDS YP_094184.1 52840385 3077960 151762..154230 1 NC_002942.5 hypothetical protein 154230 3077960 lpg0130 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094184.1 151762 D 272624 CDS YP_094185.1 52840386 3080107 complement(154334..155065) 1 NC_002942.5 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 155065 dapB 3080107 dapB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrodipicolinate reductase YP_094185.1 154334 R 272624 CDS YP_094186.1 52840387 3078880 complement(155245..155430) 1 NC_002942.5 hypothetical protein 155430 3078880 lpg0132 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094186.1 155245 R 272624 CDS YP_094187.1 52840388 3078835 155787..156479 1 NC_002942.5 activator of ProP osmoprotectant transporter 156479 proQm 3078835 proQm Legionella pneumophila subsp. pneumophila str. Philadelphia 1 activator of ProP osmoprotectant transporter YP_094187.1 155787 D 272624 CDS YP_094188.1 52840389 3078589 156480..157550 1 NC_002942.5 hypothetical protein 157550 3078589 lpg0134 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094188.1 156480 D 272624 CDS YP_094189.1 52840390 3079197 complement(157650..163277) 1 NC_002942.5 hypothetical protein 163277 sdhB 3079197 sdhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094189.1 157650 R 272624 CDS YP_094190.1 52840391 3078826 complement(163368..164792) 1 NC_002942.5 pyruvate kinase II 164792 pykA 3078826 pykA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate kinase II YP_094190.1 163368 R 272624 CDS YP_094191.1 52840392 3080547 complement(164776..165966) 1 NC_002942.5 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 165966 pgk 3080547 pgk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoglycerate kinase YP_094191.1 164776 R 272624 CDS YP_094192.1 52840393 3078191 complement(165977..167005) 1 NC_002942.5 glyceraldehyde 3-phosphate dehydrogenase 167005 gap 3078191 gap Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glyceraldehyde 3-phosphate dehydrogenase YP_094192.1 165977 R 272624 CDS YP_094193.1 52840394 3079667 complement(167051..169129) 1 NC_002942.5 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 169129 tktA 3079667 tktA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transketolase YP_094193.1 167051 R 272624 CDS YP_094194.1 52840395 3078502 169315..170649 1 NC_002942.5 hypothetical protein 170649 3078502 lpg0140 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094194.1 169315 D 272624 CDS YP_094195.1 52840396 3078426 170703..172763 1 NC_002942.5 oligopeptidase A 172763 3078426 lpg0141 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oligopeptidase A YP_094195.1 170703 D 272624 CDS YP_094196.1 52840397 3080030 173401..174849 1 NC_002942.5 IS4 family transposase TnpA 174849 3080030 lpg0142 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS4 family transposase TnpA YP_094196.1 173401 D 272624 CDS YP_094197.1 52840398 3078321 complement(174882..176057) 1 NC_002942.5 transposase TnpA or TnpA2 176057 3078321 lpg0144 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase TnpA or TnpA2 YP_094197.1 174882 R 272624 CDS YP_094198.1 52840399 3077926 complement(174882..175442) 1 NC_002942.5 transposase (01), TnpA 175442 3077926 lpg0143 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase (01), TnpA YP_094198.1 174882 R 272624 CDS YP_094199.1 52840400 3078285 complement(176091..176453) 1 NC_002942.5 site specific recombinase 176453 ccrB 3078285 ccrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 site specific recombinase YP_094199.1 176091 R 272624 CDS YP_094200.1 52840401 3078317 complement(176652..176885) 1 NC_002942.5 conserved gene, also ISR508 transposase OrfB protein; transposase B, TnpA 176885 3078317 lpg0146 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase B, TnpA YP_094200.1 176652 R 272624 CDS YP_094201.1 52840402 3079981 complement(177533..177826) 1 NC_002942.5 transposase, IS911 177826 3079981 lpg0147 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase, IS911 YP_094201.1 177533 R 272624 CDS YP_094202.1 52840403 3078322 178308..179678 1 NC_002942.5 hypothetical protein 179678 3078322 lpg0148 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094202.1 178308 D 272624 CDS YP_094203.1 52840404 3079123 complement(179810..181150) 1 NC_002942.5 hypothetical protein 181150 3079123 lpg0149 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094203.1 179810 R 272624 CDS YP_094204.1 52840405 3077919 complement(181180..182550) 1 NC_002942.5 hypothetical protein 182550 3077919 lpg0150 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094204.1 181180 R 272624 CDS YP_094205.1 52840406 3077968 182740..183804 1 NC_002942.5 hypothetical protein 183804 3077968 lpg0151 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094205.1 182740 D 272624 CDS YP_094206.1 52840407 3079050 184405..184920 1 NC_002942.5 hypothetical protein 184920 3079050 lpg0152 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094206.1 184405 D 272624 CDS YP_094207.1 52840408 3078299 complement(185908..186222) 1 NC_002942.5 hypothetical protein 186222 3078299 lpg0153 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094207.1 185908 R 272624 CDS YP_094208.1 52840409 3077920 187002..187889 1 NC_002942.5 hypothetical protein 187889 3077920 lpg0154 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094208.1 187002 D 272624 CDS YP_094209.1 52840410 3080580 complement(188236..189114) 1 NC_002942.5 sensory box protein 189114 3080580 lpg0155 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_094209.1 188236 R 272624 CDS YP_094210.1 52840411 3077907 complement(189144..190304) 1 NC_002942.5 signal transduction protein 190304 3077907 lpg0156 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal transduction protein YP_094210.1 189144 R 272624 CDS YP_094211.1 52840412 3080100 complement(190331..191104) 1 NC_002942.5 methionine aminopeptidase 191104 map-1 3080100 map-1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionine aminopeptidase YP_094211.1 190331 R 272624 CDS YP_094212.1 52840413 3080105 complement(191073..191285) 1 NC_002942.5 hypothetical protein 191285 3080105 lpg0158 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094212.1 191073 R 272624 CDS YP_094213.1 52840414 3079415 complement(191460..191939) 1 NC_002942.5 hypothetical protein 191939 3079415 lpg0159 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094213.1 191460 R 272624 CDS YP_094214.1 52840415 3079287 192160..193137 1 NC_002942.5 hypothetical protein 193137 3079287 lpg0160 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094214.1 192160 D 272624 CDS YP_094215.1 52840416 3079074 complement(193391..193852) 1 NC_002942.5 hypothetical protein 193852 3079074 lpg0161 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094215.1 193391 R 272624 CDS YP_094216.1 52840417 3077689 194022..194303 1 NC_002942.5 protein SapA-like 194303 3077689 lpg0162 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SapA-like YP_094216.1 194022 D 272624 CDS YP_094217.1 52840418 3079842 194761..195582 1 NC_002942.5 alpha/beta hydrolase 195582 3079842 lpg0163 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha/beta hydrolase YP_094217.1 194761 D 272624 CDS YP_094218.1 52840419 3078845 complement(194901..195011) 1 NC_002942.5 hypothetical protein 195011 3078845 lpg0164 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094218.1 194901 R 272624 CDS YP_094219.1 52840420 3080004 complement(195663..196118) 1 NC_002942.5 hypothetical protein 196118 3080004 lpg0165 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094219.1 195663 R 272624 CDS YP_094220.1 52840421 3080023 complement(196286..197170) 1 NC_002942.5 hypothetical protein 197170 3080023 lpg0166 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094220.1 196286 R 272624 CDS YP_094221.1 52840422 3079098 complement(197445..197855) 1 NC_002942.5 peptide chain release factor 197855 3079098 lpg0167 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide chain release factor YP_094221.1 197445 R 272624 CDS YP_094222.1 52840423 3078656 complement(197956..198681) 1 NC_002942.5 hypothetical protein 198681 3078656 lpg0168 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094222.1 197956 R 272624 CDS YP_094223.1 52840424 3078006 complement(198678..199463) 1 NC_002942.5 transmembrane protein 199463 3078006 lpg0169 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094223.1 198678 R 272624 CDS YP_094224.1 52840425 3080112 complement(199432..200187) 1 NC_002942.5 ABC transporter permease 200187 3080112 lpg0170 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094224.1 199432 R 272624 CDS YP_094225.1 52840426 3079938 complement(200453..201019) 1 NC_002942.5 hypothetical protein 201019 legU1 3079938 legU1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094225.1 200453 R 272624 CDS YP_094226.1 52840427 3079932 201209..201934 1 NC_002942.5 hypothetical protein 201934 3079932 lpg0172 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094226.1 201209 D 272624 CDS YP_094227.1 52840428 3077676 complement(202064..202924) 1 NC_002942.5 LysR family transcriptional regulator 202924 oxyR 3077676 oxyR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094227.1 202064 R 272624 CDS YP_094228.1 52840429 3079669 203005..204084 1 NC_002942.5 pyoverdine biosynthesis protein PvcA 204084 pvcA 3079669 pvcA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyoverdine biosynthesis protein PvcA YP_094228.1 203005 D 272624 CDS YP_094229.1 52840430 3080118 204074..204910 1 NC_002942.5 pyoverdine biosynthesis protein PvcB 204910 3080118 lpg0175 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyoverdine biosynthesis protein PvcB YP_094229.1 204074 D 272624 CDS YP_094230.1 52840431 3080014 204907..206349 1 NC_002942.5 hypothetical protein 206349 3080014 lpg0176 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094230.1 204907 D 272624 CDS YP_094231.1 52840432 3077827 206346..207494 1 NC_002942.5 chloramphenicol resistance protein 207494 3077827 lpg0177 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chloramphenicol resistance protein YP_094231.1 206346 D 272624 CDS YP_094232.1 52840433 3079979 207491..208723 1 NC_002942.5 hypothetical protein 208723 3079979 lpg0178 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094232.1 207491 D 272624 CDS YP_094233.1 52840434 3079937 208880..209854 1 NC_002942.5 O-methyltransferase 209854 3079937 lpg0179 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-methyltransferase YP_094233.1 208880 D 272624 CDS YP_094234.1 52840435 3079815 complement(209967..210809) 1 NC_002942.5 M48 family peptidase 210809 htpX 3079815 htpX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 M48 family peptidase YP_094234.1 209967 R 272624 CDS YP_094235.1 52840436 3079054 211023..211934 1 NC_002942.5 hypothetical protein 211934 3079054 lpg0181 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094235.1 211023 D 272624 CDS YP_094236.1 52840437 3079759 complement(211981..212433) 1 NC_002942.5 hypothetical protein 212433 3079759 lpg0182 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094236.1 211981 R 272624 CDS YP_094237.1 52840438 3079692 212762..214258 1 NC_002942.5 amine oxidase 214258 3079692 lpg0183 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amine oxidase YP_094237.1 212762 D 272624 CDS YP_094238.1 52840439 3080055 complement(214503..215387) 1 NC_002942.5 sugar ABC transporter substrate-binding protein 215387 3080055 lpg0184 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sugar ABC transporter substrate-binding protein YP_094238.1 214503 R 272624 CDS YP_094239.1 52840440 3079914 complement(215391..216131) 1 NC_002942.5 sugar ABC transporter ATP-binding protein 216131 3079914 lpg0185 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sugar ABC transporter ATP-binding protein YP_094239.1 215391 R 272624 CDS YP_094240.1 52840441 3079511 complement(216128..217069) 1 NC_002942.5 ABC sugar transporter permease 217069 3079511 lpg0186 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC sugar transporter permease YP_094240.1 216128 R 272624 CDS YP_094241.1 52840442 3079757 217228..218655 1 NC_002942.5 conserved gene, peptidase, M20/M25/M40 family; acylases; hypothetical protein 218655 3079757 lpg0187 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094241.1 217228 D 272624 CDS YP_094242.1 52840443 3077863 218775..219851 1 NC_002942.5 acyl CoA transferase/carnitine dehydratase 219851 3077863 lpg0188 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA transferase/carnitine dehydratase YP_094242.1 218775 D 272624 CDS YP_094243.1 52840444 3079944 complement(219993..220859) 1 NC_002942.5 hypothetical protein 220859 3079944 lpg0189 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094243.1 219993 R 272624 CDS YP_094244.1 52840445 3079113 complement(220962..221183) 1 NC_002942.5 hypothetical protein 221183 3079113 lpg0190 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094244.1 220962 R 272624 CDS YP_094245.1 52840446 3077932 221236..222189 1 NC_002942.5 hypothetical protein 222189 3077932 lpg0191 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094245.1 221236 D 272624 CDS YP_094246.1 52840447 3079300 complement(222394..222978) 1 NC_002942.5 heat shock hsp20 222978 3079300 lpg0192 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heat shock hsp20 YP_094246.1 222394 R 272624 CDS YP_094247.1 52840448 3080142 complement(223101..223295) 1 NC_002942.5 hypothetical protein 223295 3080142 lpg0193 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094247.1 223101 R 272624 CDS YP_094248.1 52840449 3080358 complement(223447..225696) 1 NC_002942.5 catalase/(hydro)peroxidase KatG 225696 3080358 lpg0194 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 catalase/(hydro)peroxidase KatG YP_094248.1 223447 R 272624 CDS YP_094249.1 52840450 3079257 complement(225828..226832) 1 NC_002942.5 hypothetical protein 226832 3079257 lpg0195 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094249.1 225828 R 272624 CDS YP_094250.1 52840451 3078768 complement(227034..228308) 1 NC_002942.5 hypothetical protein 228308 3078768 lpg0196 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094250.1 227034 R 272624 CDS YP_094251.1 52840452 3078875 228667..228984 1 NC_002942.5 hypothetical protein 228984 3078875 lpg0197 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094251.1 228667 D 272624 CDS YP_094252.1 52840453 3078829 229092..230123 1 NC_002942.5 hypothetical protein 230123 3078829 lpg0198 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094252.1 229092 D 272624 CDS YP_094253.1 52840454 3078533 230239..231609 1 NC_002942.5 cytochrome D ubiquinol oxidase subunit I 231609 cydA 3078533 cydA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome D ubiquinol oxidase subunit I YP_094253.1 230239 D 272624 CDS YP_094254.1 52840455 3077891 231609..232598 1 NC_002942.5 hypothetical protein 232598 qxtB 3077891 qxtB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094254.1 231609 D 272624 CDS YP_094255.1 52840456 3080147 complement(232599..233384) 1 NC_002942.5 hypothetical protein 233384 3080147 lpg0201 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094255.1 232599 R 272624 CDS YP_094256.1 52840457 3079393 complement(233381..233917) 1 NC_002942.5 hypothetical protein 233917 3079393 lpg0202 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094256.1 233381 R 272624 CDS YP_094257.1 52840458 3079133 complement(233907..235694) 1 NC_002942.5 hypothetical protein 235694 yfhG 3079133 yfhG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094257.1 233907 R 272624 CDS YP_094258.1 52840459 3079489 235777..236475 1 NC_002942.5 2-deoxy-D-gluconate 3-dehydrogenase 236475 3079489 lpg0204 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-deoxy-D-gluconate 3-dehydrogenase YP_094258.1 235777 D 272624 CDS YP_094259.1 52840460 3078020 236492..238030 1 NC_002942.5 hypothetical protein 238030 3078020 lpg0205 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094259.1 236492 D 272624 CDS YP_094260.1 52840461 3080613 complement(238035..238448) 1 NC_002942.5 hypothetical protein 238448 3080613 lpg0206 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094260.1 238035 R 272624 CDS YP_094261.1 52840462 3079087 238464..238634 1 NC_002942.5 hypothetical protein 238634 3079087 lpg0207 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094261.1 238464 D 272624 CDS YP_094262.1 52840463 3079755 238638..241697 1 NC_002942.5 serine/threonine-protein kinase 241697 pkn5 3079755 pkn5 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine/threonine-protein kinase YP_094262.1 238638 D 272624 CDS YP_094263.1 52840464 3078846 241716..243683 1 NC_002942.5 hypothetical protein 243683 3078846 lpg0209 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094263.1 241716 D 272624 CDS YP_094264.1 52840465 3079081 243721..244344 1 NC_002942.5 hypothetical protein 244344 3079081 lpg0210 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094264.1 243721 D 272624 CDS YP_094265.1 52840466 3079119 complement(244591..244992) 1 NC_002942.5 tryptophan rich sensory protein TspO 244992 tspO 3079119 tspO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophan rich sensory protein TspO YP_094265.1 244591 R 272624 CDS YP_094266.1 52840467 3078925 complement(245097..246512) 1 NC_002942.5 deoxyribodipyrimidine photolyase 246512 phrB 3078925 phrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyribodipyrimidine photolyase YP_094266.1 245097 R 272624 CDS YP_094267.1 52840468 3078578 complement(246607..247314) 1 NC_002942.5 inner membrane protein, LrgB family protein 247314 3078578 lpg0213 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inner membrane protein, LrgB family protein YP_094267.1 246607 R 272624 CDS YP_094268.1 52840469 3077749 complement(247292..247900) 1 NC_002942.5 murein hydrolase exporter, LrgA family protein 247900 3077749 lpg0214 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 murein hydrolase exporter, LrgA family protein YP_094268.1 247292 R 272624 CDS YP_094269.1 52840470 3079674 247787..248671 1 NC_002942.5 LysR family transcriptional regulator 248671 3079674 lpg0215 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094269.1 247787 D 272624 CDS YP_094270.1 52840471 3078809 248791..249003 1 NC_002942.5 hypothetical protein 249003 3078809 lpg0216 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094270.1 248791 D 272624 CDS YP_094271.1 52840472 3078716 complement(249089..250168) 1 NC_002942.5 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 250168 purK 3078716 purK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_094271.1 249089 R 272624 CDS YP_094272.1 52840473 3080087 complement(250165..250665) 1 NC_002942.5 phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE 250665 purE 3080087 purE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE YP_094272.1 250165 R 272624 CDS YP_094273.1 52840474 3078696 complement(250725..251579) 1 NC_002942.5 hypothetical protein 251579 3078696 lpg0219 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094273.1 250725 R 272624 CDS YP_094274.1 52840475 3078830 complement(251589..251942) 1 NC_002942.5 hypothetical protein 251942 3078830 lpg0220 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094274.1 251589 R 272624 CDS YP_094275.1 52840476 3078853 complement(251956..254244) 1 NC_002942.5 hypothetical protein 254244 3078853 lpg0221 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094275.1 251956 R 272624 CDS YP_094276.1 52840477 3078904 complement(254259..255779) 1 NC_002942.5 NADH dehydrogenase subunit 5 255779 3078904 lpg0222 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit 5 YP_094276.1 254259 R 272624 CDS YP_094277.1 52840478 3078494 255881..256732 1 NC_002942.5 LysR family transcriptional regulator 256732 3078494 lpg0223 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094277.1 255881 D 272624 CDS YP_094278.1 52840479 3077924 256774..258363 1 NC_002942.5 toxin secretion ABC transporter ATP-binding protein 258363 3077924 lpg0224 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 toxin secretion ABC transporter ATP-binding protein YP_094278.1 256774 D 272624 CDS YP_094279.1 52840480 3078581 258360..259346 1 NC_002942.5 RND efflux membrane fusion protein 259346 3078581 lpg0225 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RND efflux membrane fusion protein YP_094279.1 258360 D 272624 CDS YP_094280.1 52840481 3078807 259343..260740 1 NC_002942.5 multidrug efflux protein, outer membrane component 260740 3078807 lpg0226 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug efflux protein, outer membrane component YP_094280.1 259343 D 272624 CDS YP_094281.1 52840482 3078529 260923..262029 1 NC_002942.5 hypothetical protein 262029 3078529 lpg0227 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094281.1 260923 D 272624 CDS YP_094282.1 52840483 3080007 complement(262200..263765) 1 NC_002942.5 amino acid permease 263765 3080007 lpg0228 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid permease YP_094282.1 262200 R 272624 CDS YP_094283.1 52840484 3078052 complement(263913..264746) 1 NC_002942.5 heme oxygenase 264746 3078052 lpg0229 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heme oxygenase YP_094283.1 263913 R 272624 CDS YP_094284.1 52840485 3078104 complement(264958..267087) 1 NC_002942.5 sensor histidine kinase 267087 pleD 3078104 pleD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor histidine kinase YP_094284.1 264958 R 272624 CDS YP_094285.1 52840486 3080339 complement(267234..269792) 1 NC_002942.5 heavy metal transporting P-type ATPase, cation transporting 269792 3080339 lpg0231 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heavy metal transporting P-type ATPase, cation transporting YP_094285.1 267234 R 272624 CDS YP_094286.1 52840487 3080449 270036..270569 1 NC_002942.5 transcriptional regulator np20 270569 np20 3080449 np20 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator np20 YP_094286.1 270036 D 272624 CDS YP_094287.1 52840488 3079408 complement(270686..272278) 1 NC_002942.5 benzoylformate decarboxylase 272278 mdlC 3079408 mdlC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 benzoylformate decarboxylase YP_094287.1 270686 R 272624 CDS YP_094288.1 52840489 3078560 complement(272577..277121) 1 NC_002942.5 protein SidE 277121 sidE 3078560 sidE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidE YP_094288.1 272577 R 272624 CDS YP_094289.1 52840490 3077648 complement(277484..277987) 1 NC_002942.5 hypothetical protein 277987 3077648 lpg0235 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094289.1 277484 R 272624 CDS YP_094290.1 52840491 3078350 complement(278060..280039) 1 NC_002942.5 hypothetical protein 280039 3078350 lpg0236 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094290.1 278060 R 272624 CDS YP_094291.1 52840492 3079975 280320..281114 1 NC_002942.5 lipolytic protein 281114 mhpC 3079975 mhpC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipolytic protein YP_094291.1 280320 D 272624 CDS YP_094292.1 52840493 3077641 281131..282597 1 NC_002942.5 glycine betaine aldehyde dehydrogenase 282597 gbsA 3077641 gbsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine betaine aldehyde dehydrogenase YP_094292.1 281131 D 272624 CDS YP_094293.1 52840494 3079864 282572..283924 1 NC_002942.5 4-aminobutyrate aminotransferase 283924 gabT 3079864 gabT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-aminobutyrate aminotransferase YP_094293.1 282572 D 272624 CDS YP_094294.1 52840495 3078890 284008..284787 1 NC_002942.5 DNA repair protein 284787 recN 3078890 recN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA repair protein YP_094294.1 284008 D 272624 CDS YP_094295.1 52840496 3078211 285047..285979 1 NC_002942.5 glutaminase 285979 3078211 lpg0241 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutaminase YP_094295.1 285047 D 272624 CDS YP_094296.1 52840497 3078428 286103..286990 1 NC_002942.5 D-3-phosphoglycerate dehydrogenase 286990 serA 3078428 serA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-3-phosphoglycerate dehydrogenase YP_094296.1 286103 D 272624 CDS YP_094297.1 52840498 3078380 complement(287203..287802) 1 NC_002942.5 short chain dehydrogenase 287802 3078380 lpg0243 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase YP_094297.1 287203 R 272624 CDS YP_094298.1 52840499 3079816 complement(288008..289402) 1 NC_002942.5 pyridine nucleotide-disulfide oxidoreductase 289402 3079816 lpg0244 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridine nucleotide-disulfide oxidoreductase YP_094298.1 288008 R 272624 CDS YP_094299.1 52840500 3078553 complement(289454..292834) 1 NC_002942.5 NAD-glutamate dehydrogenase 292834 3078553 lpg0245 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD-glutamate dehydrogenase YP_094299.1 289454 R 272624 CDS YP_094300.1 52840501 3078057 293014..293739 1 NC_002942.5 hypothetical protein 293739 3078057 lpg0246 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094300.1 293014 D 272624 CDS YP_094301.1 52840502 3078140 293971..294924 1 NC_002942.5 hypothetical protein 294924 3078140 lpg0247 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094301.1 293971 D 272624 CDS YP_094302.1 52840503 3078246 295084..295425 1 NC_002942.5 arsenate reductase 295425 3078246 lpg0248 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arsenate reductase YP_094302.1 295084 D 272624 CDS YP_094303.1 52840504 3078565 complement(295512..296666) 1 NC_002942.5 stearoyl CoA 9-desaturase 296666 3078565 lpg0249 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stearoyl CoA 9-desaturase YP_094303.1 295512 R 272624 CDS YP_094304.1 52840505 3078247 complement(296785..298029) 1 NC_002942.5 DEAD/DEAH box helicase 298029 3078247 lpg0250 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DEAD/DEAH box helicase YP_094304.1 296785 R 272624 CDS YP_094305.1 52840506 3077732 298358..298636 1 NC_002942.5 RNA binding protein, cold-inducible rrm 298636 3077732 lpg0251 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA binding protein, cold-inducible rrm YP_094305.1 298358 D 272624 CDS YP_094306.1 52840507 3079042 298794..299489 1 NC_002942.5 hypothetical protein 299489 3079042 lpg0252 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094306.1 298794 D 272624 CDS YP_094307.1 52840508 3080484 299524..300165 1 NC_002942.5 acetyltransferase 300165 3080484 lpg0253 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_094307.1 299524 D 272624 CDS YP_094308.1 52840509 3079742 300258..300827 1 NC_002942.5 hypothetical protein 300827 3079742 lpg0254 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094308.1 300258 D 272624 CDS YP_094309.1 52840510 3078776 300982..302328 1 NC_002942.5 outer membrane channel protein 302328 3078776 lpg0255 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane channel protein YP_094309.1 300982 D 272624 CDS YP_094310.1 52840511 3078607 302309..303355 1 NC_002942.5 hypothetical protein 303355 3078607 lpg0256 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094310.1 302309 D 272624 CDS YP_094311.1 52840512 3079875 303412..304404 1 NC_002942.5 multidrug resistance secretion protein 304404 3079875 lpg0257 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance secretion protein YP_094311.1 303412 D 272624 CDS YP_094312.1 52840513 3080129 304581..306524 1 NC_002942.5 hypothetical protein 306524 3080129 lpg0258 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094312.1 304581 D 272624 CDS YP_094313.1 52840514 3077659 306543..308327 1 NC_002942.5 hypothetical protein 308327 3077659 lpg0259 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094313.1 306543 D 272624 CDS YP_094314.1 52840515 3080402 308513..308911 1 NC_002942.5 hypothetical protein 308911 3080402 lpg0260 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094314.1 308513 D 272624 CDS YP_094315.1 52840516 3078054 complement(309426..309605) 1 NC_002942.5 ISSod6 transposase, ISI301 309605 3078054 lpg0261 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISSod6 transposase, ISI301 YP_094315.1 309426 R 272624 CDS YP_094316.1 52840517 3079771 complement(309672..310310) 1 NC_002942.5 bacteriophage related DNA polymerase 310310 3079771 lpg0262 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bacteriophage related DNA polymerase YP_094316.1 309672 R 272624 CDS YP_094317.1 52840518 3077898 310567..311841 1 NC_002942.5 MFS transporter family protein 311841 3077898 lpg0263 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MFS transporter family protein YP_094317.1 310567 D 272624 CDS YP_094318.1 52840519 3078389 311920..312618 1 NC_002942.5 hypothetical protein 312618 3078389 lpg0264 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094318.1 311920 D 272624 CDS YP_094319.1 52840520 3079490 complement(312673..314214) 1 NC_002942.5 hypothetical protein 314214 3079490 lpg0265 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094319.1 312673 R 272624 CDS YP_094320.1 52840521 3078412 314443..314877 1 NC_002942.5 hypothetical protein 314877 3078412 lpg0266 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094320.1 314443 D 272624 CDS YP_094321.1 52840522 3079195 complement(314892..315944) 1 NC_002942.5 hypothetical protein 315944 corA 3079195 corA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094321.1 314892 R 272624 CDS YP_094322.1 52840523 3078566 316127..316723 1 NC_002942.5 hypothetical protein 316723 3078566 lpg0268 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094322.1 316127 D 272624 CDS YP_094323.1 52840524 3078622 316801..318363 1 NC_002942.5 hypothetical protein 318363 3078622 lpg0269 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094323.1 316801 D 272624 CDS YP_094324.1 52840525 3077913 318430..319848 1 NC_002942.5 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 319848 3077913 lpg0270 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nicotinate phosphoribosyltransferase YP_094324.1 318430 D 272624 CDS YP_094325.1 52840526 3078889 319832..320473 1 NC_002942.5 bifunctional pyrazinamidase/nicotinamidase 320473 pncA 3078889 pncA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional pyrazinamidase/nicotinamidase YP_094325.1 319832 D 272624 CDS YP_094326.1 52840527 3080570 complement(320556..320939) 1 NC_002942.5 cysteine transferase 320939 3080570 lpg0272 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cysteine transferase YP_094326.1 320556 R 272624 CDS YP_094327.1 52840528 3080067 complement(320939..322180) 1 NC_002942.5 major facilitator superfamily transporter 322180 3080067 lpg0273 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator superfamily transporter YP_094327.1 320939 R 272624 CDS YP_094328.1 52840529 3079192 322271..323134 1 NC_002942.5 LysR family transcriptional regulator 323134 3079192 lpg0274 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094328.1 322271 D 272624 CDS YP_094329.1 52840530 3078105 323554..326904 1 NC_002942.5 protein SdbA 326904 3078105 lpg0275 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdbA YP_094329.1 323554 D 272624 CDS YP_094330.1 52840531 3077853 327062..328561 1 NC_002942.5 hypothetical protein 328561 legG2 3077853 legG2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094330.1 327062 D 272624 CDS YP_094331.1 52840532 3080136 complement(328627..330849) 1 NC_002942.5 sensory box protein, GGDEF family protein, LssE 330849 3080136 lpg0277 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein, GGDEF family protein, LssE YP_094331.1 328627 R 272624 CDS YP_094332.1 52840533 3080139 complement(330852..332267) 1 NC_002942.5 sensor histidine kinase 332267 fixL 3080139 fixL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor histidine kinase YP_094332.1 330852 R 272624 CDS YP_094333.1 52840534 3078847 complement(332290..333456) 1 NC_002942.5 hypothetical protein 333456 3078847 lpg0279 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094333.1 332290 R 272624 CDS YP_094334.1 52840535 3077962 complement(333622..334503) 1 NC_002942.5 LysR family transcriptional regulator 334503 3077962 lpg0280 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_094334.1 333622 R 272624 CDS YP_094335.1 52840536 3079951 complement(334725..335909) 1 NC_002942.5 amino acid transporter 335909 3079951 lpg0281 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid transporter YP_094335.1 334725 R 272624 CDS YP_094336.1 52840537 3079203 complement(335977..336753) 1 NC_002942.5 hypothetical protein 336753 3079203 lpg0282 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094336.1 335977 R 272624 CDS YP_094337.1 52840538 3077692 336961..338172 1 NC_002942.5 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase 338172 3077692 lpg0283 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 formate dehydrogenase YP_094337.1 336961 D 272624 CDS YP_094338.1 52840539 3077949 complement(338278..339402) 1 NC_002942.5 hypothetical protein 339402 3077949 lpg0284 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094338.1 338278 R 272624 CDS YP_094339.1 52840540 3079103 339639..340322 1 NC_002942.5 hypothetical protein 340322 3079103 lpg0285 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094339.1 339639 D 272624 CDS YP_094340.1 52840541 3080062 340355..341203 1 NC_002942.5 short chain dehydrogenase/reductase oxidoreductase 341203 3080062 lpg0286 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase/reductase oxidoreductase YP_094340.1 340355 D 272624 CDS YP_094341.1 52840542 3078531 complement(342005..342622) 1 NC_002942.5 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 342622 efp 3078531 efp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 elongation factor P YP_094341.1 342005 R 272624 CDS YP_094342.1 52840543 3080127 342646..343626 1 NC_002942.5 L-lysine 2,3-aminomutase 343626 3080127 lpg0288 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-lysine 2,3-aminomutase YP_094342.1 342646 D 272624 CDS YP_094343.1 52840544 3077900 complement(343695..345779) 1 NC_002942.5 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 345779 ppk 3077900 ppk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polyphosphate kinase YP_094343.1 343695 R 272624 CDS YP_094344.1 52840545 3077702 complement(345808..347013) 1 NC_002942.5 lipoprotein 347013 3077702 lpg0290 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein YP_094344.1 345808 R 272624 CDS YP_094345.1 52840546 3079589 complement(347089..347622) 1 NC_002942.5 chromate transport protein 347622 3079589 lpg0291 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromate transport protein YP_094345.1 347089 R 272624 CDS YP_094346.1 52840547 3079231 complement(347619..348296) 1 NC_002942.5 hypothetical protein 348296 3079231 lpg0292 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094346.1 347619 R 272624 CDS YP_094347.1 52840548 3079027 348415..350853 1 NC_002942.5 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 350853 3079027 lpg0293 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl-CoA dehydrogenase YP_094347.1 348415 D 272624 CDS YP_094348.1 52840549 3077916 350967..351659 1 NC_002942.5 hypothetical protein 351659 3077916 lpg0294 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094348.1 350967 D 272624 CDS YP_094349.1 52840550 3078818 complement(351696..352358) 1 NC_002942.5 mannose-1-phosphate guanylyltransferase 352358 3078818 lpg0295 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mannose-1-phosphate guanylyltransferase YP_094349.1 351696 R 272624 CDS YP_094350.1 52840551 3079136 complement(352355..353401) 1 NC_002942.5 phosphotransferase 353401 3079136 lpg0296 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphotransferase YP_094350.1 352355 R 272624 CDS YP_094351.1 52840552 3080123 353425..356094 1 NC_002942.5 organic solvent tolerance protein 356094 ostA 3080123 ostA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 organic solvent tolerance protein YP_094351.1 353425 D 272624 CDS YP_094352.1 52840553 3079603 356219..357559 1 NC_002942.5 peptidyl-prolyl cis-trans isomerase D 357559 surA 3079603 surA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidyl-prolyl cis-trans isomerase D YP_094352.1 356219 D 272624 CDS YP_094353.1 52840554 3078878 357556..358530 1 NC_002942.5 4-hydroxythreonine-4-phosphate dehydrogenase 358530 pdxA 3078878 pdxA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-hydroxythreonine-4-phosphate dehydrogenase YP_094353.1 357556 D 272624 CDS YP_094354.1 52840555 3078159 358532..359023 1 NC_002942.5 dihydrofolate reductase 359023 3078159 lpg0300 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrofolate reductase YP_094354.1 358532 D 272624 CDS YP_094355.1 52840556 3079228 complement(359030..359575) 1 NC_002942.5 hypothetical protein 359575 3079228 lpg0301 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094355.1 359030 R 272624 CDS YP_094356.1 52840557 3079253 complement(362950..363300) 1 NC_002942.5 hypothetical protein 363300 3079253 lpg0305 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094356.1 362950 R 272624 CDS YP_094357.1 52840558 3080135 complement(363791..364132) 1 NC_002942.5 hypothetical protein 364132 3080135 lpg0306 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094357.1 363791 R 272624 CDS YP_094358.1 52840559 3079515 complement(363909..364190) 1 NC_002942.5 hypothetical protein 364190 3079515 lpg0307 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094358.1 363909 R 272624 CDS YP_094359.1 52840560 3078694 365435..366625 1 NC_002942.5 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 366625 tuf2 3078694 tuf2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 elongation factor Tu YP_094359.1 365435 D 272624 CDS YP_094360.1 52840561 3079918 366774..367145 1 NC_002942.5 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 367145 secE 3079918 secE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecE YP_094360.1 366774 D 272624 CDS YP_094361.1 52840562 3079648 367142..367696 1 NC_002942.5 transcription antitermination protein NusG 367696 nusG 3079648 nusG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription antitermination protein NusG YP_094361.1 367142 D 272624 CDS YP_094362.1 52840563 3079028 367807..368241 1 NC_002942.5 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 368241 rplK 3079028 rplK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L11 YP_094362.1 367807 D 272624 CDS YP_094363.1 52840564 3079128 368251..368946 1 NC_002942.5 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 368946 rplA 3079128 rplA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L1 YP_094363.1 368251 D 272624 CDS YP_094364.1 52840565 3079896 369119..369652 1 NC_002942.5 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 369652 rplJ 3079896 rplJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L10 YP_094364.1 369119 D 272624 CDS YP_094365.1 52840566 3080243 369683..370063 1 NC_002942.5 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 370063 rplL 3080243 rplL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L7/L12 YP_094365.1 369683 D 272624 CDS YP_094366.1 52840567 3079843 370155..374261 1 NC_002942.5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 374261 rpoB 3079843 rpoB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-directed RNA polymerase subunit beta YP_094366.1 370155 D 272624 CDS YP_094367.1 52840568 3079628 374308..378555 1 NC_002942.5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 378555 rpoC 3079628 rpoC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-directed RNA polymerase subunit beta' YP_094367.1 374308 D 272624 CDS YP_094368.1 52840569 3077823 378669..379049 1 NC_002942.5 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 379049 rpsL 3077823 rpsL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S12 YP_094368.1 378669 D 272624 CDS YP_094369.1 52840570 3078134 379070..379597 1 NC_002942.5 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 379597 rpS7 3078134 rpS7 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S7 YP_094369.1 379070 D 272624 CDS YP_094370.1 52840571 3078163 379612..381696 1 NC_002942.5 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 381696 fusA 3078163 fusA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 elongation factor G YP_094370.1 379612 D 272624 CDS YP_094371.1 52840572 3077740 381717..382907 1 NC_002942.5 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 382907 tufB 3077740 tufB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 elongation factor Tu YP_094371.1 381717 D 272624 CDS YP_094372.1 52840573 3078284 382913..383230 1 NC_002942.5 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 383230 rpsJ 3078284 rpsJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S10 YP_094372.1 382913 D 272624 CDS YP_094373.2 394893855 3080581 383268..383915 1 NC_002942.5 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 383915 rplC 3080581 rplC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L3 YP_094373.2 383268 D 272624 CDS YP_094374.1 52840575 3080019 383912..384520 1 NC_002942.5 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 384520 rplD 3080019 rplD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L4 YP_094374.1 383912 D 272624 CDS YP_094375.1 52840576 3078992 384535..384813 1 NC_002942.5 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 384813 rplW 3078992 rplW Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L23 YP_094375.1 384535 D 272624 CDS YP_094376.1 52840577 3077838 384825..385652 1 NC_002942.5 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 385652 rplB 3077838 rplB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L2 YP_094376.1 384825 D 272624 CDS YP_003856781.1 304348725 9711811 385671..385949 1 NC_002942.5 30S ribosomal protein S19 385949 9711811 lpg_3050 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S19 YP_003856781.1 385671 D 272624 CDS YP_094377.1 52840578 3079569 complement(385874..386176) 1 NC_002942.5 hypothetical protein 386176 3079569 lpg0333 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094377.1 385874 R 272624 CDS YP_094378.2 394893854 3079085 385959..386294 1 NC_002942.5 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 386294 rplV 3079085 rplV Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L22 YP_094378.2 385959 D 272624 CDS YP_094379.1 52840580 3079030 386297..386953 1 NC_002942.5 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 386953 rpsC 3079030 rpsC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S3 YP_094379.1 386297 D 272624 CDS YP_094380.1 52840581 3077747 386970..387383 1 NC_002942.5 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 387383 rplP 3077747 rplP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L16 YP_094380.1 386970 D 272624 CDS YP_094381.1 52840582 3080608 387383..387577 1 NC_002942.5 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 387577 rpmC 3080608 rpmC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L29 YP_094381.1 387383 D 272624 CDS YP_094382.1 52840583 3078617 387579..387833 1 NC_002942.5 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 387833 rpsQ 3078617 rpsQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S17 YP_094382.1 387579 D 272624 CDS YP_094383.1 52840584 3080285 387922..388287 1 NC_002942.5 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 388287 rplN 3080285 rplN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L14 YP_094383.1 387922 D 272624 CDS YP_094384.1 52840585 3080141 388300..388629 1 NC_002942.5 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 388629 rplX 3080141 rplX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L24 YP_094384.1 388300 D 272624 CDS YP_094385.2 394893853 3080064 388645..389196 1 NC_002942.5 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 389196 rplE 3080064 rplE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L5 YP_094385.2 388645 D 272624 CDS YP_094386.2 161723259 3077953 389209..389511 1 NC_002942.5 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the Legionella proteins appear to contain the zinc-binding motif; 30S ribosomal protein S14 389511 rpsN 3077953 rpsN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S14 YP_094386.2 389209 D 272624 CDS YP_094387.2 394893852 3080507 389534..389929 1 NC_002942.5 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 389929 rpsH 3080507 rpsH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S8 YP_094387.2 389534 D 272624 CDS YP_094388.1 52840589 3078059 389947..390486 1 NC_002942.5 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 390486 rplF 3078059 rplF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L6 YP_094388.1 389947 D 272624 CDS YP_094389.2 394893851 3078252 390497..390856 1 NC_002942.5 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 390856 rplR 3078252 rplR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L18 YP_094389.2 390497 D 272624 CDS YP_094390.1 52840591 3079959 390866..391372 1 NC_002942.5 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 391372 rpsE 3079959 rpsE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S5 YP_094390.1 390866 D 272624 CDS YP_094391.1 52840592 3078939 391375..391560 1 NC_002942.5 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 391560 rpmD 3078939 rpmD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L30 YP_094391.1 391375 D 272624 CDS YP_094392.1 52840593 3079437 391560..391994 1 NC_002942.5 late assembly protein; 50S ribosomal protein L15 391994 rplO 3079437 rplO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L15 YP_094392.1 391560 D 272624 CDS YP_094393.1 52840594 3080040 391991..393325 1 NC_002942.5 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 393325 secY 3080040 secY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecY YP_094393.1 391991 D 272624 CDS YP_094394.1 52840595 3080088 393342..393455 1 NC_002942.5 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 393455 rpmJ 3080088 rpmJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L36 YP_094394.1 393342 D 272624 CDS YP_094395.1 52840596 3078898 393533..393889 1 NC_002942.5 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 393889 rpsM 3078898 rpsM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S13 YP_094395.1 393533 D 272624 CDS YP_094396.1 52840597 3078031 393913..394311 1 NC_002942.5 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 394311 rpsK 3078031 rpsK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S11 YP_094396.1 393913 D 272624 CDS YP_094397.1 52840598 3078405 394328..394948 1 NC_002942.5 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 394948 rpsD 3078405 rpsD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S4 YP_094397.1 394328 D 272624 CDS YP_094398.1 52840599 3078280 394967..395959 1 NC_002942.5 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 395959 rpoA 3078280 rpoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-directed RNA polymerase subunit alpha YP_094398.1 394967 D 272624 CDS YP_094399.1 52840600 3077931 395978..396361 1 NC_002942.5 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 396361 rplQ 3077931 rplQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L17 YP_094399.1 395978 D 272624 CDS YP_094400.1 52840601 3080438 complement(396429..396917) 1 NC_002942.5 single strand binding protein 396917 ssb 3080438 ssb Legionella pneumophila subsp. pneumophila str. Philadelphia 1 single strand binding protein YP_094400.1 396429 R 272624 CDS YP_094401.1 52840602 3078652 complement(396992..398359) 1 NC_002942.5 major facilitator family transporter 398359 3078652 lpg0357 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094401.1 396992 R 272624 CDS YP_094402.1 52840603 3079191 398521..399279 1 NC_002942.5 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 399279 3079191 lpg0358 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enoyl-ACP reductase YP_094402.1 398521 D 272624 CDS YP_094403.1 52840604 3079578 399350..399763 1 NC_002942.5 acyl carrier protein 399763 acpP 3079578 acpP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl carrier protein YP_094403.1 399350 D 272624 CDS YP_094404.1 52840605 3078811 399760..400659 1 NC_002942.5 (3R)-hydroxymyristoyl-ACP dehydratase 400659 fabA 3078811 fabA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (3R)-hydroxymyristoyl-ACP dehydratase YP_094404.1 399760 D 272624 CDS YP_094405.1 52840606 3078431 400664..401956 1 NC_002942.5 3-oxoacyl-ACP synthase 401956 fabF 3078431 fabF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_094405.1 400664 D 272624 CDS YP_094406.1 52840607 3080448 401957..403234 1 NC_002942.5 3-oxoacyl-ACP synthase 403234 fabF 3080448 fabF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_094406.1 401957 D 272624 CDS YP_094407.1 52840608 3080597 403227..404072 1 NC_002942.5 lipid A biosynthesis acyltransferase 404072 waaM 3080597 waaM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipid A biosynthesis acyltransferase YP_094407.1 403227 D 272624 CDS YP_094408.1 52840609 3078385 complement(404182..404487) 1 NC_002942.5 hypothetical protein 404487 3078385 lpg0364 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094408.1 404182 R 272624 CDS YP_094409.1 52840610 3079905 complement(404662..407352) 1 NC_002942.5 hypothetical protein 407352 3079905 lpg0365 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094409.1 404662 R 272624 CDS YP_094410.1 52840611 3080494 complement(407663..408496) 1 NC_002942.5 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 408496 dapF 3080494 dapF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 diaminopimelate epimerase YP_094410.1 407663 R 272624 CDS YP_094411.1 52840612 3079383 complement(408711..409034) 1 NC_002942.5 hypothetical protein 409034 3079383 lpg0367 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094411.1 408711 R 272624 CDS YP_094412.1 52840613 3080450 409033..409140 1 NC_002942.5 hypothetical protein 409140 3080450 lpg0368 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094412.1 409033 D 272624 CDS YP_094413.1 52840614 3080299 409315..409992 1 NC_002942.5 carboxylesterase/phospholipase 409992 3080299 lpg0369 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carboxylesterase/phospholipase YP_094413.1 409315 D 272624 CDS YP_094414.1 52840615 3078019 409989..410423 1 NC_002942.5 oligoketide cyclase/lipid transporter protein 410423 3078019 lpg0370 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oligoketide cyclase/lipid transporter protein YP_094414.1 409989 D 272624 CDS YP_094415.1 52840616 3078143 410410..410682 1 NC_002942.5 hypothetical protein 410682 3078143 lpg0371 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094415.1 410410 D 272624 CDS YP_094416.1 52840617 3080080 complement(410771..411115) 1 NC_002942.5 small protein A, tmRNA-binding 411115 smpA 3080080 smpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 small protein A, tmRNA-binding YP_094416.1 410771 R 272624 CDS YP_094417.1 52840618 3079067 412548..413186 1 NC_002942.5 components of sensory transduction system 413186 3079067 lpg0373 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 components of sensory transduction system YP_094417.1 412548 D 272624 CDS YP_094418.1 52840619 3080027 complement(413499..413885) 1 NC_002942.5 hypothetical protein 413885 3080027 lpg0374 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094418.1 413499 R 272624 CDS YP_094419.1 52840620 3079793 414141..414740 1 NC_002942.5 hypothetical protein 414740 3079793 lpg0375 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094419.1 414141 D 272624 CDS YP_094420.1 52840621 3078689 complement(414780..419069) 1 NC_002942.5 protein SdhA 419069 sdhA 3078689 sdhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdhA YP_094420.1 414780 R 272624 CDS YP_094421.1 52840622 3080109 complement(419232..419975) 1 NC_002942.5 hypothetical protein 419975 3080109 lpg0377 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094421.1 419232 R 272624 CDS YP_094422.1 52840623 3077885 complement(419956..421212) 1 NC_002942.5 hypothetical protein 421212 3077885 lpg0378 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094422.1 419956 R 272624 CDS YP_094423.1 52840624 3079613 complement(421169..422623) 1 NC_002942.5 ribosomal protein S6 modification protein 422623 3079613 lpg0379 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosomal protein S6 modification protein YP_094423.1 421169 R 272624 CDS YP_094424.1 52840625 3077964 complement(422627..423346) 1 NC_002942.5 hypothetical protein 423346 3077964 lpg0380 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094424.1 422627 R 272624 CDS YP_094425.1 52840626 3078911 complement(423535..424008) 1 NC_002942.5 hypothetical protein 424008 3078911 lpg0381 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094425.1 423535 R 272624 CDS YP_094426.1 52840627 3078228 complement(424005..424571) 1 NC_002942.5 osmotically inducible protein Y 424571 osmY 3078228 osmY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 osmotically inducible protein Y YP_094426.1 424005 R 272624 CDS YP_094427.1 52840628 3079405 complement(424815..425297) 1 NC_002942.5 hypothetical protein 425297 3079405 lpg0383 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094427.1 424815 R 272624 CDS YP_094428.1 52840629 3079297 425369..428224 1 NC_002942.5 excinuclease ABC subunit A 428224 uvrA 3079297 uvrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 excinuclease ABC subunit A YP_094428.1 425369 D 272624 CDS YP_094429.1 52840630 3079797 428407..428988 1 NC_002942.5 LemA protein 428988 3079797 lpg0385 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LemA protein YP_094429.1 428407 D 272624 CDS YP_094430.1 52840631 3077687 428999..430018 1 NC_002942.5 metalloprotease; heat shock protein HtpX 430018 htpX 3077687 htpX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heat shock protein HtpX YP_094430.1 428999 D 272624 CDS YP_094431.1 52840632 3078921 complement(430045..430818) 1 NC_002942.5 ABC transporter permease 430818 3078921 lpg0387 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094431.1 430045 R 272624 CDS YP_094432.1 52840633 3079826 complement(430808..431722) 1 NC_002942.5 ABC transporter ATP-binding protein 431722 3079826 lpg0388 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094432.1 430808 R 272624 CDS YP_094433.1 52840634 3080024 431782..431895 1 NC_002942.5 hypothetical protein 431895 3080024 lpg0389 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094433.1 431782 D 272624 CDS YP_094434.1 52840635 3079134 complement(431953..433011) 1 NC_002942.5 VipA 433011 vipA 3079134 vipA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 VipA YP_094434.1 431953 R 272624 CDS YP_094435.1 52840636 3079693 complement(433098..433637) 1 NC_002942.5 SM20-like protein 433637 3079693 lpg0391 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SM20-like protein YP_094435.1 433098 R 272624 CDS YP_094436.1 52840637 3079745 complement(433822..434529) 1 NC_002942.5 zinc metalloprotease 434529 3079745 lpg0392 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc metalloprotease YP_094436.1 433822 R 272624 CDS YP_094437.1 52840638 3080567 435144..436007 1 NC_002942.5 hypothetical protein 436007 3080567 lpg0393 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094437.1 435144 D 272624 CDS YP_094438.1 52840639 3079988 complement(436108..436563) 1 NC_002942.5 methylated DNA protein cysteine S-methyltransferase 436563 3079988 lpg0394 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methylated DNA protein cysteine S-methyltransferase YP_094438.1 436108 R 272624 CDS YP_094439.1 52840640 3078762 complement(436579..436944) 1 NC_002942.5 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 436944 rplS 3078762 rplS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L19 YP_094439.1 436579 R 272624 CDS YP_094440.1 52840641 3079671 complement(436971..437741) 1 NC_002942.5 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 437741 trmD 3079671 trmD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA (guanine-N(1)-)-methyltransferase YP_094440.1 436971 R 272624 CDS YP_094441.1 52840642 3078540 complement(437723..438232) 1 NC_002942.5 16S rRNA-processing protein RimM 438232 rimM 3078540 rimM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 16S rRNA-processing protein RimM YP_094441.1 437723 R 272624 CDS YP_094442.1 52840643 3078259 438107..438241 1 NC_002942.5 hypothetical protein 438241 3078259 lpg0398 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094442.1 438107 D 272624 CDS YP_094443.1 52840644 3078125 complement(438238..438498) 1 NC_002942.5 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 438498 rpsP 3078125 rpsP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S16 YP_094443.1 438238 R 272624 CDS YP_094444.1 52840645 3078976 complement(438585..439961) 1 NC_002942.5 signal recognition particle protein Ffh 439961 ffh 3078976 ffh Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal recognition particle protein Ffh YP_094444.1 438585 R 272624 CDS YP_094445.1 52840646 3078719 complement(440213..440887) 1 NC_002942.5 hypothetical protein 440887 3078719 lpg0401 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094445.1 440213 R 272624 CDS YP_094446.1 52840647 3080228 441321..443024 1 NC_002942.5 ankyrin repeat-containing protein 443024 legA9 3080228 legA9 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094446.1 441321 D 272624 CDS YP_094447.1 52840648 3080218 443204..444748 1 NC_002942.5 1700007B22 gene product; ankyrin repeat-containing protein 444748 legA7 3080218 legA7 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094447.1 443204 D 272624 CDS YP_094448.1 52840649 3080560 445085..446488 1 NC_002942.5 amino acid antiporter 446488 3080560 lpg0404 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid antiporter YP_094448.1 445085 D 272624 CDS YP_094449.1 52840650 3078124 446478..447068 1 NC_002942.5 hypothetical protein 447068 3078124 lpg0405 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094449.1 446478 D 272624 CDS YP_094450.1 52840651 3079856 447268..447609 1 NC_002942.5 hypothetical protein 447609 3079856 lpg0406 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094450.1 447268 D 272624 CDS YP_094451.1 52840652 3080026 complement(447822..448265) 1 NC_002942.5 hypothetical protein 448265 3080026 lpg0407 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094451.1 447822 R 272624 CDS YP_094452.1 52840653 3078486 complement(448284..448832) 1 NC_002942.5 inner (transmembrane) protein 448832 3078486 lpg0408 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inner (transmembrane) protein YP_094452.1 448284 R 272624 CDS YP_094453.1 52840654 3079956 449520..450248 1 NC_002942.5 hypothetical protein 450248 3079956 lpg0409 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094453.1 449520 D 272624 CDS YP_094454.1 52840655 3079962 450232..450777 1 NC_002942.5 hypothetical protein 450777 3079962 lpg0410 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094454.1 450232 D 272624 CDS YP_094455.1 52840656 3080539 450758..451789 1 NC_002942.5 cytochrome c oxidase assembly protein 451789 3080539 lpg0411 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c oxidase assembly protein YP_094455.1 450758 D 272624 CDS YP_094456.1 52840657 3080056 451779..452663 1 NC_002942.5 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 452663 3080056 lpg0412 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protoheme IX farnesyltransferase YP_094456.1 451779 D 272624 CDS YP_094457.1 52840658 3080382 452673..453314 1 NC_002942.5 SCO1/SenC family protein 453314 3080382 lpg0413 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SCO1/SenC family protein YP_094457.1 452673 D 272624 CDS YP_094458.1 52840659 3078116 453681..454589 1 NC_002942.5 glutathione synthase, ribosomal protein S6 modification protein 454589 3078116 lpg0414 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione synthase, ribosomal protein S6 modification protein YP_094458.1 453681 D 272624 CDS YP_094459.1 52840660 3078895 complement(454593..454838) 1 NC_002942.5 hypothetical protein 454838 3078895 lpg0415 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094459.1 454593 R 272624 CDS YP_094460.1 52840661 3078858 455156..456646 1 NC_002942.5 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 456646 zwf 3078858 zwf Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucose-6-phosphate 1-dehydrogenase YP_094460.1 455156 D 272624 CDS YP_094461.1 52840662 3078980 456615..457346 1 NC_002942.5 6-phosphogluconolactonase 457346 pgl 3078980 pgl Legionella pneumophila subsp. pneumophila str. Philadelphia 1 6-phosphogluconolactonase YP_094461.1 456615 D 272624 CDS YP_094462.1 52840663 3079398 457334..459172 1 NC_002942.5 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 459172 edd 3079398 edd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphogluconate dehydratase YP_094462.1 457334 D 272624 CDS YP_094463.1 52840664 3079132 459147..460154 1 NC_002942.5 glucokinase 460154 glk 3079132 glk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucokinase YP_094463.1 459147 D 272624 CDS YP_094464.1 52840665 3078274 460141..460803 1 NC_002942.5 multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase/4-hydroxy-2-oxoglutarate aldolase 460803 eda 3078274 eda Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_094464.1 460141 D 272624 CDS YP_094465.1 52840666 3080130 460916..462337 1 NC_002942.5 D-xylose (galactose, arabinose)-proton symporter 462337 ywtG 3080130 ywtG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-xylose (galactose, arabinose)-proton symporter YP_094465.1 460916 D 272624 CDS YP_094466.1 52840667 3080143 complement(462427..463776) 1 NC_002942.5 glucoamylase 463776 legY 3080143 legY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucoamylase YP_094466.1 462427 R 272624 CDS YP_094467.1 52840668 3080520 complement(463902..464138) 1 NC_002942.5 Cro family transcriptional regulator 464138 yozG 3080520 yozG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Cro family transcriptional regulator YP_094467.1 463902 R 272624 CDS YP_094468.1 52840669 3078127 complement(464225..464764) 1 NC_002942.5 hypothetical protein 464764 3078127 lpg0424 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094468.1 464225 R 272624 CDS YP_094469.1 52840670 3080526 complement(464892..465890) 1 NC_002942.5 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 465890 hemH 3080526 hemH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ferrochelatase YP_094469.1 464892 R 272624 CDS YP_094470.1 52840671 3080047 complement(465998..466231) 1 NC_002942.5 cold shock protein CspD 466231 cspD 3080047 cspD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock protein CspD YP_094470.1 465998 R 272624 CDS YP_094471.1 52840672 3078423 466588..466899 1 NC_002942.5 diadenosine tetraphosphate (Ap4A) hydrolase 466899 3078423 lpg0427 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 diadenosine tetraphosphate (Ap4A) hydrolase YP_094471.1 466588 D 272624 CDS YP_094472.1 52840673 3078509 complement(467113..467541) 1 NC_002942.5 hypothetical protein 467541 3078509 lpg0428 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094472.1 467113 R 272624 CDS YP_094473.1 52840674 3080081 467559..468911 1 NC_002942.5 outer membrane efflux protein 468911 oprM 3080081 oprM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane efflux protein YP_094473.1 467559 D 272624 CDS YP_094474.1 52840675 3080364 469036..470088 1 NC_002942.5 multidrug resistance efflux pump PmrA 470088 3080364 lpg0430 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance efflux pump PmrA YP_094474.1 469036 D 272624 CDS YP_094475.1 52840676 3079977 470060..470998 1 NC_002942.5 hypothetical protein 470998 3079977 lpg0431 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094475.1 470060 D 272624 CDS YP_094476.1 52840677 3080116 470965..471864 1 NC_002942.5 hypothetical protein 471864 3080116 lpg0432 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094476.1 470965 D 272624 CDS YP_094477.1 52840678 3078091 471886..472266 1 NC_002942.5 hypothetical protein 472266 3078091 lpg0433 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094477.1 471886 D 272624 CDS YP_094478.1 52840679 3079832 complement(472268..472795) 1 NC_002942.5 hypothetical protein 472795 3079832 lpg0434 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094478.1 472268 R 272624 CDS YP_094479.1 52840680 3080542 472961..473572 1 NC_002942.5 SAM-dependent methyltransferase 473572 3080542 lpg0435 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SAM-dependent methyltransferase YP_094479.1 472961 D 272624 CDS YP_094480.1 52840681 3080510 complement(473739..474548) 1 NC_002942.5 ankyrin repeat-containing protein 474548 legA11 3080510 legA11 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094480.1 473739 R 272624 CDS YP_094481.1 52840682 3080325 474811..476811 1 NC_002942.5 hypothetical protein 476811 3080325 lpg0437 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094481.1 474811 D 272624 CDS YP_094482.1 52840683 3079922 complement(477096..477314) 1 NC_002942.5 hypothetical protein 477314 3079922 lpg0438 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094482.1 477096 R 272624 CDS YP_094483.1 52840684 3080338 complement(477490..478539) 1 NC_002942.5 hypothetical protein 478539 3080338 lpg0439 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094483.1 477490 R 272624 CDS YP_094484.1 52840685 3080496 478631..478843 1 NC_002942.5 hypothetical protein 478843 3080496 lpg0440 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094484.1 478631 D 272624 CDS YP_094485.1 52840686 3078297 479014..479274 1 NC_002942.5 IcmT protein 479274 icmT 3078297 icmT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmT protein YP_094485.1 479014 D 272624 CDS YP_094486.1 52840687 3079271 479275..479619 1 NC_002942.5 IcmS protein 479619 icmS 3079271 icmS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmS protein YP_094486.1 479275 D 272624 CDS YP_094487.1 52840688 3077636 479719..480081 1 NC_002942.5 IcmR 480081 icmR 3077636 icmR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmR YP_094487.1 479719 D 272624 CDS YP_094488.1 52840689 3079741 480148..480747 1 NC_002942.5 IcmQ protein 480747 icmQ 3079741 icmQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmQ protein YP_094488.1 480148 D 272624 CDS YP_094489.1 52840690 3077691 480922..482064 1 NC_002942.5 IcmP protein 482064 icmP 3077691 icmP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmP protein YP_094489.1 480922 D 272624 CDS YP_094490.1 52840691 3079255 482061..484412 1 NC_002942.5 IcmO protein 484412 icmO 3079255 icmO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmO protein YP_094490.1 482061 D 272624 CDS YP_094491.1 52840692 3078331 484816..485385 1 NC_002942.5 protein LphA 485385 lphA 3078331 lphA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LphA YP_094491.1 484816 D 272624 CDS YP_094492.1 52840693 3079712 485397..485681 1 NC_002942.5 IcmM (DotJ) 485681 icmM 3079712 icmM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmM (DotJ) YP_094492.1 485397 D 272624 CDS YP_094493.1 52840694 3079658 485697..486335 1 NC_002942.5 IcmL protein 486335 icmL 3079658 icmL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmL protein YP_094493.1 485697 D 272624 CDS YP_094494.1 52840695 3078065 486335..487420 1 NC_002942.5 IcmK protein 487420 icmK 3078065 icmK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmK protein YP_094494.1 486335 D 272624 CDS YP_094495.1 52840696 3078914 487425..490571 1 NC_002942.5 IcmE protein 490571 icmE 3078914 icmE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmE protein YP_094495.1 487425 D 272624 CDS YP_094496.1 52840697 3079958 490586..491395 1 NC_002942.5 IcmG protein 491395 icmG 3079958 icmG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmG protein YP_094496.1 490586 D 272624 CDS YP_094497.1 52840698 3079911 491403..491987 1 NC_002942.5 hypothetical protein 491987 icmC 3079911 icmC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094497.1 491403 D 272624 CDS YP_094498.1 52840699 3080054 492130..492411 1 NC_002942.5 IcmD protein 492411 icmD 3080054 icmD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmD protein YP_094498.1 492130 D 272624 CDS YP_094499.1 52840700 3079735 492591..493235 1 NC_002942.5 IcmJ protein 493235 icmJ 3079735 icmJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmJ protein YP_094499.1 492591 D 272624 CDS YP_094500.1 52840701 3080126 493271..496300 1 NC_002942.5 IcmB protein 496300 icmB 3080126 icmB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmB protein YP_094500.1 493271 D 272624 CDS YP_094501.1 52840702 3080272 complement(496446..497702) 1 NC_002942.5 TphA (ProP) 497702 tphA 3080272 tphA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TphA (ProP) YP_094501.1 496446 R 272624 CDS YP_094502.1 52840703 3079541 complement(497705..500626) 1 NC_002942.5 IcmF 500626 icmF 3079541 icmF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmF YP_094502.1 497705 R 272624 CDS YP_094503.1 52840704 3079292 complement(500626..501411) 1 NC_002942.5 IcmH (DotU) 501411 icmH 3079292 icmH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmH (DotU) YP_094503.1 500626 R 272624 CDS YP_094504.1 52840705 3079293 complement(501696..503285) 1 NC_002942.5 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 503285 purH 3079293 purH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_094504.1 501696 R 272624 CDS YP_094505.1 52840706 3079587 complement(503312..504181) 1 NC_002942.5 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 504181 prmA 3079587 prmA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L11 methyltransferase YP_094505.1 503312 R 272624 CDS YP_094506.1 52840707 3079504 complement(504183..505532) 1 NC_002942.5 acetyl CoA carboxylase, biotin carboxylase subunit 505532 accC 3079504 accC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl CoA carboxylase, biotin carboxylase subunit YP_094506.1 504183 R 272624 CDS YP_094507.1 52840708 3079386 complement(505539..506021) 1 NC_002942.5 acetyl-CoA carboxylase biotin carboxyl carrier protein 506021 3079386 lpg0463 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl-CoA carboxylase biotin carboxyl carrier protein YP_094507.1 505539 R 272624 CDS YP_094508.1 52840709 3079902 complement(506035..506472) 1 NC_002942.5 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 506472 aroQ 3079902 aroQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-dehydroquinate dehydratase YP_094508.1 506035 R 272624 CDS YP_094509.1 52840710 3079155 complement(506479..506718) 1 NC_002942.5 hypothetical protein 506718 3079155 lpg0465 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094509.1 506479 R 272624 CDS YP_094510.1 52840711 3079509 506656..508464 1 NC_002942.5 catalyzes the formation of oxaloacetate from pyruvate; pyruvate carboxylase subunit B 508464 3079509 lpg0466 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate carboxylase subunit B YP_094510.1 506656 D 272624 CDS YP_094511.1 52840712 3078684 509030..510661 1 NC_002942.5 zinc metalloprotease 510661 3078684 lpg0467 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc metalloprotease YP_094511.1 509030 D 272624 CDS YP_094512.1 52840713 3078619 complement(510663..511514) 1 NC_002942.5 lipase A 511514 3078619 lpg0468 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipase A YP_094512.1 510663 R 272624 CDS YP_094513.1 52840714 3079245 511961..512734 1 NC_002942.5 hypothetical protein 512734 3079245 lpg0469 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094513.1 511961 D 272624 CDS YP_094514.1 52840715 3079058 complement(512912..513922) 1 NC_002942.5 fructose bisphosphate aldolase 513922 3079058 lpg0470 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fructose bisphosphate aldolase YP_094514.1 512912 R 272624 CDS YP_094515.1 52840716 3080060 complement(514072..514818) 1 NC_002942.5 phenol hydroxylase 514818 poxF 3080060 poxF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phenol hydroxylase YP_094515.1 514072 R 272624 CDS YP_094516.1 52840717 3077975 514890..515432 1 NC_002942.5 IcmC protein 515432 3077975 lpg0472 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmC protein YP_094516.1 514890 D 272624 CDS YP_094517.1 52840718 3078867 complement(515576..515872) 1 NC_002942.5 hypothetical protein 515872 3078867 lpg0473 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094517.1 515576 R 272624 CDS YP_094518.1 52840719 3078557 516084..516827 1 NC_002942.5 CDP-diacylglycerol--serine O-phosphatidyltransferase 516827 3078557 lpg0474 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_094518.1 516084 D 272624 CDS YP_094519.1 52840720 3079566 complement(517068..517337) 1 NC_002942.5 sugar transport PTS system phosphocarrier HPr protein 517337 ptsH 3079566 ptsH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sugar transport PTS system phosphocarrier HPr protein YP_094519.1 517068 R 272624 CDS YP_094520.1 52840721 3079274 complement(517528..517827) 1 NC_002942.5 sigma-54 modulation protein 517827 3079274 lpg0476 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sigma-54 modulation protein YP_094520.1 517528 R 272624 CDS YP_094521.1 52840722 3079161 complement(517854..519248) 1 NC_002942.5 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 519248 3079161 lpg0477 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA polymerase factor sigma-54 YP_094521.1 517854 R 272624 CDS YP_094522.1 52840723 3078839 complement(519458..519622) 1 NC_002942.5 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 519622 rpmG 3078839 rpmG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L33 YP_094522.1 519458 R 272624 CDS YP_094523.1 52840724 3079135 complement(519637..519873) 1 NC_002942.5 required for 70S ribosome assembly; 50S ribosomal protein L28 519873 rpmB 3079135 rpmB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L28 YP_094523.1 519637 R 272624 CDS YP_094524.1 52840725 3079268 519971..520132 1 NC_002942.5 hypothetical protein 520132 3079268 lpg0480 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094524.1 519971 D 272624 CDS YP_094525.1 52840726 3079809 520139..520819 1 NC_002942.5 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 520819 trmB 3079809 trmB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA (guanine-N(7)-)-methyltransferase YP_094525.1 520139 D 272624 CDS YP_094526.1 52840727 3080620 520792..521955 1 NC_002942.5 endo-1,4 beta-glucanase 521955 3080620 lpg0482 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endo-1,4 beta-glucanase YP_094526.1 520792 D 272624 CDS YP_094527.1 52840728 3078572 522033..523520 1 NC_002942.5 ankyrin repeat-containing protein 523520 legA12 3078572 legA12 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094527.1 522033 D 272624 CDS YP_094528.1 52840729 3080373 523728..524870 1 NC_002942.5 protease subunit HflK 524870 hflK 3080373 hflK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protease subunit HflK YP_094528.1 523728 D 272624 CDS YP_094529.1 52840730 3078430 524867..525787 1 NC_002942.5 membrane protease subunit HflC 525787 hflC 3078430 hflC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane protease subunit HflC YP_094529.1 524867 D 272624 CDS YP_094530.1 52840731 3079391 525922..527217 1 NC_002942.5 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 527217 purA 3079391 purA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylosuccinate synthetase YP_094530.1 525922 D 272624 CDS YP_094531.1 52840732 3079143 527438..528013 1 NC_002942.5 hypothetical protein 528013 3079143 lpg0487 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094531.1 527438 D 272624 CDS YP_094532.1 52840733 3079691 528190..528624 1 NC_002942.5 IS4 family transposase 528624 3079691 lpg0488 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS4 family transposase YP_094532.1 528190 D 272624 CDS YP_094533.1 52840734 3078253 528685..528975 1 NC_002942.5 hypothetical protein 528975 3078253 lpg0489 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094533.1 528685 D 272624 CDS YP_094534.1 52840735 3078655 complement(529250..529564) 1 NC_002942.5 arginine repressor ArgR 529564 3078655 lpg0490 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine repressor ArgR YP_094534.1 529250 R 272624 CDS YP_094535.1 52840736 3080049 529838..530572 1 NC_002942.5 amino acid ABC transporter substrate-binding protein 530572 3080049 lpg0491 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid ABC transporter substrate-binding protein YP_094535.1 529838 D 272624 CDS YP_094536.1 52840737 3078482 530551..531216 1 NC_002942.5 amino acid (glutamine) ABC transporter permease 531216 yqiY 3078482 yqiY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid (glutamine) ABC transporter permease YP_094536.1 530551 D 272624 CDS YP_094537.1 52840738 3078184 531200..531868 1 NC_002942.5 amino acid (glutamine) ABC transporter ATP-binding protein 531868 3078184 lpg0493 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid (glutamine) ABC transporter ATP-binding protein YP_094537.1 531200 D 272624 CDS YP_094538.1 52840739 3079765 531865..533082 1 NC_002942.5 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 533082 argG 3079765 argG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 argininosuccinate synthase YP_094538.1 531865 D 272624 CDS YP_094539.1 52840740 3078500 532985..534310 1 NC_002942.5 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 534310 argH 3078500 argH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 argininosuccinate lyase YP_094539.1 532985 D 272624 CDS YP_094540.1 52840741 3078506 534313..535428 1 NC_002942.5 ornithine carbamoyltransferase 535428 argF 3078506 argF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ornithine carbamoyltransferase YP_094540.1 534313 D 272624 CDS YP_094541.1 52840742 3080125 complement(535517..536992) 1 NC_002942.5 adenosine deaminase 536992 3080125 lpg0497 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenosine deaminase YP_094541.1 535517 R 272624 CDS YP_094542.1 52840743 3078083 537107..538285 1 NC_002942.5 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein 538285 3078083 lpg0498 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein YP_094542.1 537107 D 272624 CDS YP_094543.1 52840744 3079438 complement(538358..539695) 1 NC_002942.5 carboxy-terminal protease 539695 3079438 lpg0499 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carboxy-terminal protease YP_094543.1 538358 R 272624 CDS YP_094544.1 52840745 3078219 complement(539776..540945) 1 NC_002942.5 M24/M37 family peptidase 540945 3078219 lpg0500 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 M24/M37 family peptidase YP_094544.1 539776 R 272624 CDS YP_094545.1 52840746 3078678 complement(540905..542449) 1 NC_002942.5 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 542449 pgm 3078678 pgm Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoglyceromutase YP_094545.1 540905 R 272624 CDS YP_094546.1 52840747 3080124 complement(542925..544196) 1 NC_002942.5 phosphatidylcholine hydrolyzing phospholipase 544196 3080124 lpg0502 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidylcholine hydrolyzing phospholipase YP_094546.1 542925 R 272624 CDS YP_094547.1 52840748 3078541 544546..545262 1 NC_002942.5 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 545262 uppS 3078541 uppS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 undecaprenyl pyrophosphate synthase YP_094547.1 544546 D 272624 CDS YP_094548.1 52840749 3078212 545216..546070 1 NC_002942.5 phosphatidate cytidylyltransferase 546070 cdsA 3078212 cdsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidate cytidylyltransferase YP_094548.1 545216 D 272624 CDS YP_094549.1 52840750 3079130 546028..547455 1 NC_002942.5 membrane associated zinc metalloprotease 547455 yaeL 3079130 yaeL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane associated zinc metalloprotease YP_094549.1 546028 D 272624 CDS YP_094550.1 52840751 3080609 547578..549938 1 NC_002942.5 hypothetical protein 549938 3080609 lpg0506 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094550.1 547578 D 272624 CDS YP_094551.1 52840752 3078282 550052..550552 1 NC_002942.5 outer membrane protein OmpH 550552 3078282 lpg0507 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane protein OmpH YP_094551.1 550052 D 272624 CDS YP_094552.1 52840753 3079142 550566..551585 1 NC_002942.5 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase 551585 lpxD 3079142 lpxD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase YP_094552.1 550566 D 272624 CDS YP_094553.1 52840754 3079144 complement(551331..551666) 1 NC_002942.5 hypothetical protein 551666 3079144 lpg0509 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094553.1 551331 R 272624 CDS YP_094554.1 52840755 3078543 551703..552155 1 NC_002942.5 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 552155 fabZ 3078543 fabZ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (3R)-hydroxymyristoyl-ACP dehydratase YP_094554.1 551703 D 272624 CDS YP_094555.1 52840756 3079518 552152..552922 1 NC_002942.5 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 552922 lpxA 3079518 lpxA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylglucosamine acyltransferase YP_094555.1 552152 D 272624 CDS YP_094556.1 52840757 3080432 552926..553330 1 NC_002942.5 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 553330 3080432 lpg0512 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 camphor resistance protein CrcB YP_094556.1 552926 D 272624 CDS YP_094557.1 52840758 3080110 553352..554632 1 NC_002942.5 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 554632 serS 3080110 serS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 seryl-tRNA synthetase YP_094557.1 553352 D 272624 CDS YP_094558.1 52840759 3078899 554771..555892 1 NC_002942.5 hypothetical protein 555892 3078899 lpg0514 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094558.1 554771 D 272624 CDS YP_094559.1 52840760 3078705 556665..557597 1 NC_002942.5 phytanoyl-CoA dioxygenase 557597 legD2 3078705 legD2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phytanoyl-CoA dioxygenase YP_094559.1 556665 D 272624 CDS YP_094560.1 52840761 3078075 557618..558406 1 NC_002942.5 hypothetical protein 558406 3078075 lpg0516 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094560.1 557618 D 272624 CDS YP_094561.1 52840762 3079420 complement(558434..559264) 1 NC_002942.5 related to diketogulonate reductase; aldo/keto reductase 559264 ytbE 3079420 ytbE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aldo/keto reductase YP_094561.1 558434 R 272624 CDS YP_094562.1 52840763 3078250 complement(559574..560422) 1 NC_002942.5 hypothetical protein 560422 3078250 lpg0518 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094562.1 559574 R 272624 CDS YP_094563.1 52840764 3079989 complement(560931..563144) 1 NC_002942.5 hypothetical protein 563144 3079989 lpg0519 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094563.1 560931 R 272624 CDS YP_094564.1 52840765 3079376 complement(563556..564326) 1 NC_002942.5 UbiE/COQ5 family methlytransferase 564326 3079376 lpg0520 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UbiE/COQ5 family methlytransferase YP_094564.1 563556 R 272624 CDS YP_094565.1 52840766 3078570 complement(564280..564888) 1 NC_002942.5 hypothetical protein 564888 3078570 lpg0521 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094565.1 564280 R 272624 CDS YP_094566.1 52840767 3078664 complement(564885..565352) 1 NC_002942.5 acetyltransferase 565352 3078664 lpg0522 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_094566.1 564885 R 272624 CDS YP_094567.1 52840768 3078214 complement(565504..566067) 1 NC_002942.5 aminoglycoside N (6')-acetyltransferase 566067 aacA4 3078214 aacA4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminoglycoside N (6')-acetyltransferase YP_094567.1 565504 R 272624 CDS YP_094568.1 52840769 3078072 566512..567138 1 NC_002942.5 virulence protein 567138 3078072 lpg0525 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 virulence protein YP_094568.1 566512 D 272624 CDS YP_094569.1 52840770 3078144 complement(567168..567602) 1 NC_002942.5 hypothetical protein 567602 3078144 lpg0526 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094569.1 567168 R 272624 CDS YP_094570.1 52840771 3077957 complement(567697..568848) 1 NC_002942.5 hypothetical protein 568848 3077957 lpg0527 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094570.1 567697 R 272624 CDS YP_094571.1 52840772 3078202 569140..569532 1 NC_002942.5 succinate dehydrogenase cytochrome b556 subunit C 569532 sdhC 3078202 sdhC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate dehydrogenase cytochrome b556 subunit C YP_094571.1 569140 D 272624 CDS YP_094572.1 52840773 3077776 569526..569873 1 NC_002942.5 succinate dehydrogenase hydrophobic membrane anchor protein subunit D 569873 sdhD 3077776 sdhD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate dehydrogenase hydrophobic membrane anchor protein subunit D YP_094572.1 569526 D 272624 CDS YP_094573.1 52840774 3077812 569875..571644 1 NC_002942.5 succinate dehydrogenase flavoprotein subunit A 571644 sdhA 3077812 sdhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate dehydrogenase flavoprotein subunit A YP_094573.1 569875 D 272624 CDS YP_094574.1 52840775 3079929 571657..572379 1 NC_002942.5 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 572379 sdhB 3079929 sdhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate dehydrogenase iron-sulfur subunit YP_094574.1 571657 D 272624 CDS YP_094575.1 52840776 3077748 572413..575247 1 NC_002942.5 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 575247 sucA 3077748 sucA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-oxoglutarate dehydrogenase E1 YP_094575.1 572413 D 272624 CDS YP_094576.1 52840777 3080610 575283..576512 1 NC_002942.5 dihydrolipoamide succinyltransferase 576512 sucB 3080610 sucB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrolipoamide succinyltransferase YP_094576.1 575283 D 272624 CDS YP_094577.1 52840778 3078611 576519..577739 1 NC_002942.5 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 577739 sucC 3078611 sucC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinyl-CoA synthetase subunit beta YP_094577.1 576519 D 272624 CDS YP_094578.1 52840779 3077875 577814..578689 1 NC_002942.5 succinyl CoA synthetase alpha chain 578689 sucD 3077875 sucD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinyl CoA synthetase alpha chain YP_094578.1 577814 D 272624 CDS YP_094579.1 52840780 3080076 579103..579750 1 NC_002942.5 pyridoxamine 5'-phosphate oxidase 579750 pdxH 3080076 pdxH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridoxamine 5'-phosphate oxidase YP_094579.1 579103 D 272624 CDS YP_094580.1 52840781 3079998 580363..580734 1 NC_002942.5 transmission trait enhancer LetE 580734 3079998 lpg0537 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmission trait enhancer LetE YP_094580.1 580363 D 272624 CDS YP_094581.1 52840782 3078827 complement(580406..580738) 1 NC_002942.5 hypothetical protein 580738 3078827 lpg0538 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094581.1 580406 R 272624 CDS YP_094582.1 52840783 3079164 complement(580805..581194) 1 NC_002942.5 hypothetical protein 581194 3079164 lpg0539 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094582.1 580805 R 272624 CDS YP_094583.1 52840784 3078478 581844..583127 1 NC_002942.5 major facilitator family transporter 583127 3078478 lpg0540 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094583.1 581844 D 272624 CDS YP_094584.1 52840785 3079863 583330..584814 1 NC_002942.5 hypothetical protein 584814 3079863 lpg0541 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094584.1 583330 D 272624 CDS YP_094585.1 52840786 3079659 585004..585285 1 NC_002942.5 Fis family transcriptional regulator 585285 fis 3079659 fis Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Fis family transcriptional regulator YP_094585.1 585004 D 272624 CDS YP_094586.1 52840787 3078296 complement(585347..586294) 1 NC_002942.5 ribose-phosphate pyrophosphokinase 586294 prsA 3078296 prsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribose-phosphate pyrophosphokinase YP_094586.1 585347 R 272624 CDS YP_094587.1 52840788 3080121 complement(586260..586448) 1 NC_002942.5 hypothetical protein 586448 3080121 lpg0544 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094587.1 586260 R 272624 CDS YP_094588.1 52840789 3079777 586504..586674 1 NC_002942.5 hypothetical protein 586674 3079777 lpg0546 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094588.1 586504 D 272624 CDS YP_094589.1 52840790 3080005 complement(586676..587275) 1 NC_002942.5 molecular chaperone LolB 587275 3080005 lpg0547 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 molecular chaperone LolB YP_094589.1 586676 R 272624 CDS YP_094590.1 52840791 3080128 587251..587850 1 NC_002942.5 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 587850 coaD 3080128 coaD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphopantetheine adenylyltransferase YP_094590.1 587251 D 272624 CDS YP_094591.1 52840792 3080150 587834..589558 1 NC_002942.5 gamma-glutamyltranspeptidase 589558 3080150 lpg0549 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 gamma-glutamyltranspeptidase YP_094591.1 587834 D 272624 CDS YP_094592.1 52840793 3078582 complement(589656..591872) 1 NC_002942.5 hypothetical protein 591872 3078582 lpg0550 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094592.1 589656 R 272624 CDS YP_094593.1 52840794 3080063 complement(592083..592856) 1 NC_002942.5 1-acyl-sn-glycerol-3-phosphate acyltransferase 592856 plsC 3080063 plsC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_094593.1 592083 R 272624 CDS YP_094594.1 52840795 3078413 complement(592883..593203) 1 NC_002942.5 suppressor of GroEL (SugE) 593203 sugE 3078413 sugE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 suppressor of GroEL (SugE) YP_094594.1 592883 R 272624 CDS YP_094595.1 52840796 3078782 complement(593345..594229) 1 NC_002942.5 aminoglycoside phosphotransferase 594229 3078782 lpg0553 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminoglycoside phosphotransferase YP_094595.1 593345 R 272624 CDS YP_094596.1 52840797 3078667 complement(594470..595537) 1 NC_002942.5 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 595537 dinP 3078667 dinP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase IV YP_094596.1 594470 R 272624 CDS YP_094597.1 52840798 3079573 complement(595977..596597) 1 NC_002942.5 hypothetical protein 596597 3079573 lpg0556 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094597.1 595977 R 272624 CDS YP_094598.1 52840799 3077988 complement(596672..597496) 1 NC_002942.5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 597496 mutM 3077988 mutM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 formamidopyrimidine-DNA glycosylase YP_094598.1 596672 R 272624 CDS YP_094599.1 52840800 3080153 597907..599094 1 NC_002942.5 stearoyl-CoA-9-desaturase 599094 3080153 lpg0558 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stearoyl-CoA-9-desaturase YP_094599.1 597907 D 272624 CDS YP_094600.1 52840801 3080151 complement(599136..599534) 1 NC_002942.5 hypothetical protein 599534 3080151 lpg0559 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094600.1 599136 R 272624 CDS YP_094601.1 52840802 3079967 599794..600540 1 NC_002942.5 acetyoacetyl CoA reductase 600540 phaB 3079967 phaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyoacetyl CoA reductase YP_094601.1 599794 D 272624 CDS YP_094602.1 52840803 3078036 600719..601465 1 NC_002942.5 acetyoacetyl CoA reductase 601465 phaB 3078036 phaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyoacetyl CoA reductase YP_094602.1 600719 D 272624 CDS YP_094603.1 52840804 3077961 601595..601993 1 NC_002942.5 hypothetical protein 601993 3077961 lpg0562 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094603.1 601595 D 272624 CDS YP_094604.1 52840805 3078103 602138..602494 1 NC_002942.5 hypothetical protein 602494 3078103 lpg0563 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094604.1 602138 D 272624 CDS YP_094605.1 52840806 3078024 complement(602739..603809) 1 NC_002942.5 hypothetical protein 603809 3078024 lpg0564 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094605.1 602739 R 272624 CDS YP_094606.1 52840807 3078084 603867..604484 1 NC_002942.5 spore maturation protein A 604484 3078084 lpg0565 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spore maturation protein A YP_094606.1 603867 D 272624 CDS YP_094607.1 52840808 3078844 604481..605014 1 NC_002942.5 spore maturation protein B 605014 spmB 3078844 spmB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spore maturation protein B YP_094607.1 604481 D 272624 CDS YP_094608.1 52840809 3080543 complement(605145..606578) 1 NC_002942.5 M24/M37 family peptidase 606578 3080543 lpg0567 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 M24/M37 family peptidase YP_094608.1 605145 R 272624 CDS YP_094609.1 52840810 3078672 606769..608040 1 NC_002942.5 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 608040 tyrS 3078672 tyrS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tyrosyl-tRNA synthetase YP_094609.1 606769 D 272624 CDS YP_094610.1 52840811 3079533 complement(611310..611660) 1 NC_002942.5 hypothetical protein 611660 3079533 lpg0572 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094610.1 611310 R 272624 CDS YP_094611.1 52840812 3079501 complement(612151..612492) 1 NC_002942.5 hypothetical protein 612492 3079501 lpg0573 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094611.1 612151 R 272624 CDS YP_094612.1 52840813 3079499 complement(612269..612550) 1 NC_002942.5 hypothetical protein 612550 3079499 lpg0574 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094612.1 612269 R 272624 CDS YP_094613.1 52840814 3079181 complement(613387..613923) 1 NC_002942.5 transferase 613923 yrdA 3079181 yrdA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transferase YP_094613.1 613387 R 272624 CDS YP_094614.1 52840815 3079964 complement(613930..615294) 1 NC_002942.5 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 615294 gor 3079964 gor Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione reductase YP_094614.1 613930 R 272624 CDS YP_094615.1 52840816 3079107 614238..614369 1 NC_002942.5 hypothetical protein 614369 3079107 lpg0579 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094615.1 614238 D 272624 CDS YP_094616.1 52840817 3080591 complement(615519..616499) 1 NC_002942.5 catalyzes the formation of inosine from adenosine; adenosine deaminase 616499 add 3080591 add Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenosine deaminase YP_094616.1 615519 R 272624 CDS YP_094617.1 52840818 3078271 616597..616782 1 NC_002942.5 hypothetical protein 616782 3078271 lpg0581 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094617.1 616597 D 272624 CDS YP_094618.1 52840819 3077704 616847..617326 1 NC_002942.5 hypothetical protein 617326 3077704 lpg0582 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094618.1 616847 D 272624 CDS YP_094619.1 52840820 3080600 complement(617366..618619) 1 NC_002942.5 phosphate transporter 618619 3080600 lpg0583 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphate transporter YP_094619.1 617366 R 272624 CDS YP_094620.1 52840821 3078749 complement(618629..619300) 1 NC_002942.5 phosphate transport regulator 619300 3078749 lpg0584 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphate transport regulator YP_094620.1 618629 R 272624 CDS YP_094621.1 52840822 3079615 619488..620252 1 NC_002942.5 hypothetical protein 620252 3079615 lpg0585 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094621.1 619488 D 272624 CDS YP_094622.1 52840823 3079559 620555..621118 1 NC_002942.5 transcriptional regulator 621118 3079559 lpg0586 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator YP_094622.1 620555 D 272624 CDS YP_094623.1 52840824 3080467 621102..621530 1 NC_002942.5 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 621530 yqgF 3080467 yqgF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Holliday junction resolvase-like protein YP_094623.1 621102 D 272624 CDS YP_094624.1 52840825 3078132 621580..622473 1 NC_002942.5 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 622473 pyrB 3078132 pyrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartate carbamoyltransferase YP_094624.1 621580 D 272624 CDS YP_094625.1 52840826 3079519 complement(622587..622973) 1 NC_002942.5 hypothetical protein 622973 3079519 lpg0589 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094625.1 622587 R 272624 CDS YP_094626.1 52840827 3078424 complement(623078..624589) 1 NC_002942.5 competence related protein ComM 624589 comM 3078424 comM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 competence related protein ComM YP_094626.1 623078 R 272624 CDS YP_094627.1 52840828 3079384 complement(624654..624914) 1 NC_002942.5 hypothetical protein 624914 3079384 lpg0591 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094627.1 624654 R 272624 CDS YP_094628.1 52840829 3080044 625023..625397 1 NC_002942.5 nitrogen regulatory P-II transcription regulator 625397 glnK 3080044 glnK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitrogen regulatory P-II transcription regulator YP_094628.1 625023 D 272624 CDS YP_094629.1 52840830 3080002 complement(625407..625988) 1 NC_002942.5 5-formyltetrahydrofolate cyclo-ligase 625988 3080002 lpg0593 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 5-formyltetrahydrofolate cyclo-ligase YP_094629.1 625407 R 272624 CDS YP_094630.1 52840831 3079852 626235..626420 1 NC_002942.5 hypothetical protein 626420 3079852 lpg0594 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094630.1 626235 D 272624 CDS YP_094631.1 52840832 3079260 626434..627249 1 NC_002942.5 4-amino-4-deoxychorismate lyase 627249 3079260 lpg0595 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-amino-4-deoxychorismate lyase YP_094631.1 626434 D 272624 CDS YP_094632.1 52840833 3079443 complement(627276..627971) 1 NC_002942.5 hypothetical protein 627971 3079443 lpg0596 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094632.1 627276 R 272624 CDS YP_094633.1 52840834 3078638 628114..630315 1 NC_002942.5 hypothetical protein 630315 aas 3078638 aas Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094633.1 628114 D 272624 CDS YP_094634.1 52840835 3078972 630316..630735 1 NC_002942.5 hypothetical protein 630735 3078972 lpg0598 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094634.1 630316 D 272624 CDS YP_094635.1 52840836 3078715 complement(631254..633014) 1 NC_002942.5 poly-beta-hydroxybutyrate polymerase 633014 3078715 lpg0599 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 poly-beta-hydroxybutyrate polymerase YP_094635.1 631254 R 272624 CDS YP_094636.1 52840837 3078504 633437..633898 1 NC_002942.5 rrf2 family protein 633898 3078504 lpg0600 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rrf2 family protein YP_094636.1 633437 D 272624 CDS YP_094637.1 52840838 3079217 633891..635339 1 NC_002942.5 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 635339 ycf24 3079217 ycf24 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cysteine desulfurase YP_094637.1 633891 D 272624 CDS YP_094638.1 52840839 3078479 635341..636093 1 NC_002942.5 ATP transporter ABC binding component, ATP-binding protein 636093 3078479 lpg0602 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP transporter ABC binding component, ATP-binding protein YP_094638.1 635341 D 272624 CDS YP_094639.1 52840840 3078484 636090..637376 1 NC_002942.5 ABC transporter permease 637376 3078484 lpg0603 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094639.1 636090 D 272624 CDS YP_094640.1 52840841 3080101 637366..638610 1 NC_002942.5 aminotransferase 638610 3080101 lpg0604 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminotransferase YP_094640.1 637366 D 272624 CDS YP_094641.1 52840842 3079574 638607..639056 1 NC_002942.5 nitrogen fixation protein (Fe-S cluster formation) NifU 639056 3079574 lpg0605 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitrogen fixation protein (Fe-S cluster formation) NifU YP_094641.1 638607 D 272624 CDS YP_094642.1 52840843 3078743 639092..639463 1 NC_002942.5 metal-sulfur cluster biosynthetic enzyme 639463 3078743 lpg0606 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metal-sulfur cluster biosynthetic enzyme YP_094642.1 639092 D 272624 CDS YP_094643.1 52840844 3079139 639466..640419 1 NC_002942.5 lysyl tRNA synthetase 640419 3079139 lpg0607 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lysyl tRNA synthetase YP_094643.1 639466 D 272624 CDS YP_094644.1 52840845 3079348 complement(640492..641406) 1 NC_002942.5 SAM-dependent methyltransferase 641406 3079348 lpg0608 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SAM-dependent methyltransferase YP_094644.1 640492 R 272624 CDS YP_094645.1 52840846 3077746 complement(641653..642426) 1 NC_002942.5 alanyl-tRNA synthetase 642426 alaS 3077746 alaS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alanyl-tRNA synthetase YP_094645.1 641653 R 272624 CDS YP_094646.1 52840847 3078583 complement(642300..643607) 1 NC_002942.5 major facilitator family transporter 643607 3078583 lpg0610 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094646.1 642300 R 272624 CDS YP_094647.1 52840848 3080612 644249..645562 1 NC_002942.5 metal ion transporter 645562 3080612 lpg0611 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metal ion transporter YP_094647.1 644249 D 272624 CDS YP_094648.1 52840849 3078744 complement(645622..646668) 1 NC_002942.5 alcohol dehydrogenase 646668 3078744 lpg0612 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alcohol dehydrogenase YP_094648.1 645622 R 272624 CDS YP_094649.1 52840850 3080470 complement(646869..647192) 1 NC_002942.5 hypothetical protein 647192 3080470 lpg0613 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094649.1 646869 R 272624 CDS YP_094650.1 52840851 3080571 647400..647804 1 NC_002942.5 hypothetical protein 647804 3080571 lpg0614 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094650.1 647400 D 272624 CDS YP_094651.1 52840852 3080336 complement(647840..648553) 1 NC_002942.5 polypeptide deformylase 648553 3080336 lpg0615 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polypeptide deformylase YP_094651.1 647840 R 272624 CDS YP_094652.1 52840853 3079032 648782..650032 1 NC_002942.5 conserved gene, may be fused protein; 7-cyano-7-deazaguanine reductase 650032 3079032 lpg0616 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 7-cyano-7-deazaguanine reductase YP_094652.1 648782 D 272624 CDS YP_094653.1 52840854 3080071 650436..651527 1 NC_002942.5 major outer membrane protein 651527 3080071 lpg0617 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major outer membrane protein YP_094653.1 650436 D 272624 CDS YP_094654.1 52840855 3078708 complement(651687..652259) 1 NC_002942.5 3-methyladenine DNA glycosylase 652259 tag 3078708 tag Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-methyladenine DNA glycosylase YP_094654.1 651687 R 272624 CDS YP_094655.1 52840856 3080417 652576..652956 1 NC_002942.5 glyoxylase 652956 3080417 lpg0619 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glyoxylase YP_094655.1 652576 D 272624 CDS YP_094656.1 52840857 3078588 complement(653057..654031) 1 NC_002942.5 hypothetical protein 654031 3078588 lpg0620 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094656.1 653057 R 272624 CDS YP_094657.1 52840858 3080361 complement(654121..655545) 1 NC_002942.5 protein SidA 655545 sidA 3080361 sidA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidA YP_094657.1 654121 R 272624 CDS YP_094658.1 52840859 3079632 complement(655706..657649) 1 NC_002942.5 transmembrane protein 657649 3079632 lpg0622 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094658.1 655706 R 272624 CDS YP_094659.1 52840860 3078804 complement(657760..658152) 1 NC_002942.5 hypothetical protein 658152 3078804 lpg0623 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094659.1 657760 R 272624 CDS YP_094660.1 52840861 3080168 658289..658666 1 NC_002942.5 hypothetical protein 658666 3080168 lpg0624 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094660.1 658289 D 272624 CDS YP_094661.1 52840862 3078547 658819..660174 1 NC_002942.5 hypothetical protein 660174 3078547 lpg0625 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094661.1 658819 D 272624 CDS YP_094662.1 52840863 3080214 complement(660200..662407) 1 NC_002942.5 DNA uptake/competence protein ComA 662407 3080214 lpg0626 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA uptake/competence protein ComA YP_094662.1 660200 R 272624 CDS YP_094663.1 52840864 3080096 complement(662485..662934) 1 NC_002942.5 type IV pilin 662934 pilE3 3080096 pilE3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilin YP_094663.1 662485 R 272624 CDS YP_094664.1 52840865 3079854 complement(662946..666464) 1 NC_002942.5 type IV fimbrial biogenesis PilY1-like protein 666464 3079854 lpg0628 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV fimbrial biogenesis PilY1-like protein YP_094664.1 662946 R 272624 CDS YP_094665.1 52840866 3078469 complement(666468..666980) 1 NC_002942.5 Tfp pilus assembly protein PilX 666980 3078469 lpg0629 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Tfp pilus assembly protein PilX YP_094665.1 666468 R 272624 CDS YP_094666.1 52840867 3078563 complement(666977..668044) 1 NC_002942.5 type IV fimbrial biogenesis PilW related protein, transmembrane) 668044 3078563 lpg0630 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV fimbrial biogenesis PilW related protein, transmembrane) YP_094666.1 666977 R 272624 CDS YP_094667.1 52840868 3078759 complement(668041..668580) 1 NC_002942.5 type IV fimbrial biogenesis protein PilV 668580 3078759 lpg0631 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV fimbrial biogenesis protein PilV YP_094667.1 668041 R 272624 CDS YP_094668.1 52840869 3078249 complement(668593..669300) 1 NC_002942.5 type IV pre-pilin 669300 3078249 lpg0632 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pre-pilin YP_094668.1 668593 R 272624 CDS YP_094669.1 52840870 3079666 complement(669522..670427) 1 NC_002942.5 polysaccharide deacetylase 670427 3079666 lpg0633 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polysaccharide deacetylase YP_094669.1 669522 R 272624 CDS YP_094670.1 52840871 3078117 complement(670559..671908) 1 NC_002942.5 hypothetical protein 671908 3078117 lpg0634 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094670.1 670559 R 272624 CDS YP_094671.1 52840872 3077650 672196..673677 1 NC_002942.5 melitin resistance protein 673677 3077650 lpg0635 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 melitin resistance protein YP_094671.1 672196 D 272624 CDS YP_094672.1 52840873 3080199 673832..674497 1 NC_002942.5 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 674497 tdk 3080199 tdk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thymidine kinase YP_094672.1 673832 D 272624 CDS YP_094673.1 52840874 3079997 674545..675816 1 NC_002942.5 major facilitator family transporter 675816 3079997 lpg0637 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094673.1 674545 D 272624 CDS YP_094674.1 52840875 3077722 675829..677112 1 NC_002942.5 major facilitator family transporter 677112 3077722 lpg0638 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094674.1 675829 D 272624 CDS YP_094675.1 52840876 3077717 677109..678332 1 NC_002942.5 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 678332 deoB 3077717 deoB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphopentomutase YP_094675.1 677109 D 272624 CDS YP_094676.1 52840877 3079586 678519..679067 1 NC_002942.5 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 679067 hslV 3079586 hslV Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent protease peptidase subunit YP_094676.1 678519 D 272624 CDS YP_094677.1 52840878 3080206 679051..680394 1 NC_002942.5 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 680394 hslU 3080206 hslU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent protease ATP-binding subunit HslU YP_094677.1 679051 D 272624 CDS YP_094678.1 52840879 3080161 680594..682168 1 NC_002942.5 hypothetical protein 682168 3080161 lpg0642 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094678.1 680594 D 272624 CDS YP_094679.1 52840880 3078458 complement(682215..683453) 1 NC_002942.5 ribonuclease BN 683453 3078458 lpg0643 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease BN YP_094679.1 682215 R 272624 CDS YP_094680.1 52840881 3078443 683868..688331 1 NC_002942.5 hypothetical protein 688331 3078443 lpg0644 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094680.1 683868 D 272624 CDS YP_094681.1 52840882 3077887 690883..692928 1 NC_002942.5 conserved gene, may be truncated RtxA; hypothetical protein 692928 3077887 lpg0645 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094681.1 690883 D 272624 CDS YP_094682.1 52840883 3078390 693107..693706 1 NC_002942.5 trp repressor binding protein 693706 wrbA 3078390 wrbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 trp repressor binding protein YP_094682.1 693107 D 272624 CDS YP_094683.1 52840884 3078799 693821..695227 1 NC_002942.5 hypothetical protein 695227 3078799 lpg0647 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094683.1 693821 D 272624 CDS YP_094684.1 52840885 3078490 696023..696805 1 NC_002942.5 exodeoxyribonuclease III 696805 xth 3078490 xth Legionella pneumophila subsp. pneumophila str. Philadelphia 1 exodeoxyribonuclease III YP_094684.1 696023 D 272624 CDS YP_094685.1 52840886 3078536 696777..697568 1 NC_002942.5 hypothetical protein 697568 xthA1 3078536 xthA1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094685.1 696777 D 272624 CDS YP_094686.1 52840887 3078606 697705..697932 1 NC_002942.5 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 697932 rpmE 3078606 rpmE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L31 YP_094686.1 697705 D 272624 CDS YP_094687.1 52840888 3079966 698059..699294 1 NC_002942.5 malate oxidoreductase 699294 3079966 lpg0651 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malate oxidoreductase YP_094687.1 698059 D 272624 CDS YP_094688.1 52840889 3079633 699505..700797 1 NC_002942.5 major facilitator family transporter 700797 3079633 lpg0652 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094688.1 699505 D 272624 CDS YP_094689.1 52840890 3078860 700778..702055 1 NC_002942.5 major facilitator family transporter 702055 3078860 lpg0653 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_094689.1 700778 D 272624 CDS YP_094690.1 52840891 3080158 complement(702084..702902) 1 NC_002942.5 DNA adenine methylase 702902 dam 3080158 dam Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA adenine methylase YP_094690.1 702084 R 272624 CDS YP_094691.1 52840892 3080278 complement(703073..704299) 1 NC_002942.5 tryptophan/tyrosine permease 704299 3080278 lpg0655 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophan/tyrosine permease YP_094691.1 703073 R 272624 CDS YP_094692.1 52840893 3079280 complement(704468..705658) 1 NC_002942.5 tryptophan/tyrosine permease 705658 3079280 lpg0656 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophan/tyrosine permease YP_094692.1 704468 R 272624 CDS YP_094693.1 52840894 3080577 complement(705669..706418) 1 NC_002942.5 outer membrane protein, OmpA family protein 706418 3080577 lpg0657 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane protein, OmpA family protein YP_094693.1 705669 R 272624 CDS YP_094694.1 52840895 3079305 706807..707664 1 NC_002942.5 HlyD family secretion protein 707664 3079305 lpg0658 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HlyD family secretion protein YP_094694.1 706807 D 272624 CDS YP_094695.1 52840896 3079105 707667..709409 1 NC_002942.5 ABC transporter ElsE 709409 3079105 lpg0659 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ElsE YP_094695.1 707667 D 272624 CDS YP_094696.1 52840897 3079597 709427..710548 1 NC_002942.5 ABC transporter permease 710548 3079597 lpg0660 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094696.1 709427 D 272624 CDS YP_094697.1 52840898 3079772 710548..711672 1 NC_002942.5 ABC transporter permease 711672 3079772 lpg0661 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094697.1 710548 D 272624 CDS YP_094698.1 52840899 3080477 711681..713120 1 NC_002942.5 major facilitator superfamily multidrug-efflux transporter 713120 3080477 lpg0662 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator superfamily multidrug-efflux transporter YP_094698.1 711681 D 272624 CDS YP_094699.1 52840900 3078758 complement(713454..715274) 1 NC_002942.5 soluble lytic murein transglycosylase 715274 3078758 lpg0663 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 soluble lytic murein transglycosylase YP_094699.1 713454 R 272624 CDS YP_094700.1 52840901 3080225 complement(715277..715930) 1 NC_002942.5 D-ribulose-5-phosphate-3-epimerase 715930 rpe 3080225 rpe Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-ribulose-5-phosphate-3-epimerase YP_094700.1 715277 R 272624 CDS YP_094701.1 52840902 3080185 complement(716146..716610) 1 NC_002942.5 transmembrane protein 716610 3080185 lpg0665 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094701.1 716146 R 272624 CDS YP_094702.1 52840903 3078009 complement(716607..717386) 1 NC_002942.5 hypothetical protein 717386 3078009 lpg0666 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094702.1 716607 R 272624 CDS YP_094703.1 52840904 3077946 complement(717379..718248) 1 NC_002942.5 hypothetical protein 718248 3077946 lpg0667 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094703.1 717379 R 272624 CDS YP_094704.1 52840905 3080111 complement(718250..718468) 1 NC_002942.5 hypothetical protein 718468 3080111 lpg0668 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094704.1 718250 R 272624 CDS YP_094705.1 52840906 3078435 complement(718254..718508) 1 NC_002942.5 hypothetical protein 718508 3078435 lpg0669 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094705.1 718254 R 272624 CDS YP_094706.1 52840907 3079188 718789..719871 1 NC_002942.5 hypothetical protein 719871 3079188 lpg0670 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094706.1 718789 D 272624 CDS YP_094707.1 52840908 3079960 719987..722203 1 NC_002942.5 NADH dehydrogenase transmembrane protein 722203 ndh 3079960 ndh Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase transmembrane protein YP_094707.1 719987 D 272624 CDS YP_094708.1 52840909 3077646 722245..723009 1 NC_002942.5 converts acetoacetate to acetone and carbon dioxide; acetoacetate decarboxylase 723009 3077646 lpg0672 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetoacetate decarboxylase YP_094708.1 722245 D 272624 CDS YP_094709.1 52840910 3078791 723047..723319 1 NC_002942.5 signal peptide protein 723319 3078791 lpg0673 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide protein YP_094709.1 723047 D 272624 CDS YP_094710.1 52840911 3080424 723312..724625 1 NC_002942.5 adenylate cyclase 724625 3080424 lpg0674 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylate cyclase YP_094710.1 723312 D 272624 CDS YP_094711.1 52840912 3077730 complement(724645..725484) 1 NC_002942.5 hypothetical protein 725484 3077730 lpg0675 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094711.1 724645 R 272624 CDS YP_094712.1 52840913 3078017 complement(725453..726280) 1 NC_002942.5 hypothetical protein 726280 3078017 lpg0676 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094712.1 725453 R 272624 CDS YP_094713.1 52840914 3078041 726557..726823 1 NC_002942.5 hypothetical protein 726823 3078041 lpg0677 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094713.1 726557 D 272624 CDS YP_094714.1 52840915 3079514 complement(726983..727747) 1 NC_002942.5 arginine ABC transporter substrate-binding protein 727747 3079514 lpg0678 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine ABC transporter substrate-binding protein YP_094714.1 726983 R 272624 CDS YP_094715.1 52840916 3079286 727873..730614 1 NC_002942.5 adenylyl transferase 730614 3079286 lpg0679 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylyl transferase YP_094715.1 727873 D 272624 CDS YP_094716.1 52840917 3079076 730825..732093 1 NC_002942.5 dipeptidyl aminopeptidase/acylaminoacyl peptidase 732093 3079076 lpg0680 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dipeptidyl aminopeptidase/acylaminoacyl peptidase YP_094716.1 730825 D 272624 CDS YP_094717.1 52840918 3078154 732160..732732 1 NC_002942.5 lipoprotein 732732 3078154 lpg0681 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein YP_094717.1 732160 D 272624 CDS YP_094718.1 52840919 3078110 732710..733651 1 NC_002942.5 ABC transporter ATP-binding protein 733651 3078110 lpg0682 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094718.1 732710 D 272624 CDS YP_094719.1 52840920 3078834 733666..734784 1 NC_002942.5 transmembrane protein, ABC-type multidrug transport system 734784 3078834 lpg0683 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein, ABC-type multidrug transport system YP_094719.1 733666 D 272624 CDS YP_094720.1 52840921 3078955 734908..736314 1 NC_002942.5 hypothetical protein 736314 3078955 lpg0684 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094720.1 734908 D 272624 CDS YP_094721.1 52840922 3080010 complement(736392..737699) 1 NC_002942.5 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 737699 rimO 3080010 rimO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosomal protein S12 methylthiotransferase YP_094721.1 736392 R 272624 CDS YP_094722.1 52840923 3080420 complement(737789..739579) 1 NC_002942.5 hypothetical protein 739579 dsbD 3080420 dsbD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094722.1 737789 R 272624 CDS YP_094723.1 52840924 3079884 739735..740025 1 NC_002942.5 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring; co-chaperonin GroES 740025 groES 3079884 groES Legionella pneumophila subsp. pneumophila str. Philadelphia 1 co-chaperonin GroES YP_094723.1 739735 D 272624 CDS YP_094724.1 52840925 3078335 740047..741699 1 NC_002942.5 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 741699 groEL 3078335 groEL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 molecular chaperone GroEL YP_094724.1 740047 D 272624 CDS YP_094725.1 52840926 3080093 741822..742262 1 NC_002942.5 DNA binding stress protein 742262 3080093 lpg0689 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA binding stress protein YP_094725.1 741822 D 272624 CDS YP_094726.1 52840927 3079053 742489..744636 1 NC_002942.5 hypothetical protein 744636 3079053 lpg0690 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094726.1 742489 D 272624 CDS YP_094727.1 52840928 3077958 complement(744892..746772) 1 NC_002942.5 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 746772 parE 3077958 parE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA topoisomerase IV subunit B YP_094727.1 744892 R 272624 CDS YP_094728.1 52840929 3080559 746894..748714 1 NC_002942.5 ABC type dipeptide/oligopeptide/nickel transport, ATPase component 748714 dppF 3080559 dppF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC type dipeptide/oligopeptide/nickel transport, ATPase component YP_094728.1 746894 D 272624 CDS YP_094729.1 52840930 3079284 748803..753083 1 NC_002942.5 LigA, interaptin 753083 3079284 lpg0693 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LigA, interaptin YP_094729.1 748803 D 272624 CDS YP_094730.2 161723258 3077743 complement(753445..755154) 1 NC_002942.5 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 755154 proS 3077743 proS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prolyl-tRNA synthetase YP_094730.2 753445 R 272624 CDS YP_094731.1 52840932 3080630 755316..758165 1 NC_002942.5 ankyrin repeat-containing protein 758165 legA8 3080630 legA8 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_094731.1 755316 D 272624 CDS YP_094732.1 52840933 3080303 complement(758172..759884) 1 NC_002942.5 hypothetical protein 759884 3080303 lpg0696 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094732.1 758172 R 272624 CDS YP_094733.1 52840934 3079791 complement(759971..762277) 1 NC_002942.5 conserved gene, perhaps also carbonic anhydrase; sulfate transporter 762277 sul1 3079791 sul1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfate transporter YP_094733.1 759971 R 272624 CDS YP_094734.1 52840935 3079869 complement(762468..763319) 1 NC_002942.5 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 763319 3079869 lpg0698 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 C32 tRNA thiolase YP_094734.1 762468 R 272624 CDS YP_094735.1 52840936 3079326 complement(763337..764704) 1 NC_002942.5 outer membrane protein TolC 764704 3079326 lpg0699 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane protein TolC YP_094735.1 763337 R 272624 CDS YP_094736.1 52840937 3079402 complement(764716..765390) 1 NC_002942.5 protein-L-isoaspartate-O-methyltransferase 765390 pcm 3079402 pcm Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein-L-isoaspartate-O-methyltransferase YP_094736.1 764716 R 272624 CDS YP_094737.2 161723257 3079968 765547..766731 1 NC_002942.5 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 766731 kbl 3079968 kbl Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-amino-3-ketobutyrate CoA ligase YP_094737.2 765547 D 272624 CDS YP_094738.1 52840939 3080574 766813..767841 1 NC_002942.5 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 767841 tdh 3080574 tdh Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-threonine 3-dehydrogenase YP_094738.1 766813 D 272624 CDS YP_094739.1 52840940 3080527 767884..769557 1 NC_002942.5 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 769557 3080527 lpg0703 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094739.1 767884 D 272624 CDS YP_094740.1 52840941 3080499 769599..770210 1 NC_002942.5 enhanced entry protein EnhA 770210 enhA 3080499 enhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhA YP_094740.1 769599 D 272624 CDS YP_094741.1 52840942 3080624 770320..770757 1 NC_002942.5 transporter component 770757 3080624 lpg0705 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter component YP_094741.1 770320 D 272624 CDS YP_094742.1 52840943 3078239 770649..771182 1 NC_002942.5 transporter component 771182 3078239 lpg0706 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter component YP_094742.1 770649 D 272624 CDS YP_094743.1 52840944 3077654 complement(771222..772394) 1 NC_002942.5 (outer) membrane protein 772394 3077654 lpg0707 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (outer) membrane protein YP_094743.1 771222 R 272624 CDS YP_094744.1 52840945 3077816 complement(772451..773413) 1 NC_002942.5 IcmL-like protein 773413 3077816 lpg0708 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmL-like protein YP_094744.1 772451 R 272624 CDS YP_094745.1 52840946 3078004 complement(773426..774415) 1 NC_002942.5 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 774415 3078004 lpg0709 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 formimidoylglutamase YP_094745.1 773426 R 272624 CDS YP_094746.1 52840947 3078195 774672..775481 1 NC_002942.5 sepiapterin reductase 775481 yueD 3078195 yueD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sepiapterin reductase YP_094746.1 774672 D 272624 CDS YP_094747.1 52840948 3078507 775439..776692 1 NC_002942.5 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 776692 hutI 3078507 hutI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazolonepropionase YP_094747.1 775439 D 272624 CDS YP_094748.1 52840949 3079020 776719..777414 1 NC_002942.5 endo-1,4-beta-xylanase-like 777414 yjeA 3079020 yjeA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endo-1,4-beta-xylanase-like YP_094748.1 776719 D 272624 CDS YP_094749.1 52840950 3078933 777414..779414 1 NC_002942.5 oligopeptide transporter 779414 3078933 lpg0713 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oligopeptide transporter YP_094749.1 777414 D 272624 CDS YP_094750.1 52840951 3078781 complement(779576..780667) 1 NC_002942.5 sensor histidine kinase 780667 3078781 lpg0714 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor histidine kinase YP_094750.1 779576 R 272624 CDS YP_094751.1 52840952 3079323 complement(780630..781301) 1 NC_002942.5 two component response regulator 781301 3079323 lpg0715 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component response regulator YP_094751.1 780630 R 272624 CDS YP_094752.1 52840953 3078063 781434..782447 1 NC_002942.5 hypothetical protein 782447 3078063 lpg0716 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094752.1 781434 D 272624 CDS YP_094753.1 52840954 3080042 complement(782548..783009) 1 NC_002942.5 hypothetical protein 783009 3080042 lpg0717 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094753.1 782548 R 272624 CDS YP_094754.1 52840955 3079238 complement(783098..784345) 1 NC_002942.5 proton/sodium-glutamate symport protein 784345 3079238 lpg0718 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proton/sodium-glutamate symport protein YP_094754.1 783098 R 272624 CDS YP_094755.1 52840956 3078324 complement(784467..787232) 1 NC_002942.5 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 787232 valS 3078324 valS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 valyl-tRNA synthetase YP_094755.1 784467 R 272624 CDS YP_094756.1 52840957 3079576 complement(787491..790538) 1 NC_002942.5 multidrug resistance protein 790538 3079576 lpg0720 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance protein YP_094756.1 787491 R 272624 CDS YP_094757.1 52840958 3079265 complement(790655..791917) 1 NC_002942.5 RND efflux membrane fusion protein, acriflavin resistance protein E 791917 3079265 lpg0721 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RND efflux membrane fusion protein, acriflavin resistance protein E YP_094757.1 790655 R 272624 CDS YP_094758.1 52840959 3078737 792158..792562 1 NC_002942.5 hypothetical protein 792562 3078737 lpg0722 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094758.1 792158 D 272624 CDS YP_094759.1 52840960 3079175 792628..793065 1 NC_002942.5 hypothetical protein 793065 3079175 lpg0723 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094759.1 792628 D 272624 CDS YP_094760.1 52840961 3078674 793190..793501 1 NC_002942.5 hypothetical protein 793501 3078674 lpg0724 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094760.1 793190 D 272624 CDS YP_094761.1 52840962 3078752 793529..794782 1 NC_002942.5 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 794782 glyA 3078752 glyA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine hydroxymethyltransferase YP_094761.1 793529 D 272624 CDS YP_094762.1 52840963 3078714 794785..795252 1 NC_002942.5 transcriptional regulator NrdR 795252 nrdR 3078714 nrdR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator NrdR YP_094762.1 794785 D 272624 CDS YP_094763.1 52840964 3079339 795382..795753 1 NC_002942.5 transcription termination factor NusB 795753 nusB 3079339 nusB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription termination factor NusB YP_094763.1 795382 D 272624 CDS YP_094764.1 52840965 3080405 795725..796702 1 NC_002942.5 thiamine monophosphate kinase 796702 thiL 3080405 thiL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiamine monophosphate kinase YP_094764.1 795725 D 272624 CDS YP_094765.1 52840966 3078778 796792..797274 1 NC_002942.5 phosphatidylglycerophosphatase A 797274 pgpA 3078778 pgpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidylglycerophosphatase A YP_094765.1 796792 D 272624 CDS YP_094766.1 52840967 3079781 797274..798326 1 NC_002942.5 transmembrane permease 798326 3079781 lpg0730 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane permease YP_094766.1 797274 D 272624 CDS YP_094767.1 52840968 3080481 complement(798318..799055) 1 NC_002942.5 hypothetical protein 799055 3080481 lpg0731 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094767.1 798318 R 272624 CDS YP_094768.1 52840969 3080149 complement(799065..799703) 1 NC_002942.5 hypothetical protein 799703 3080149 lpg0732 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094768.1 799065 R 272624 CDS YP_094769.1 52840970 3079562 799869..801317 1 NC_002942.5 hypothetical protein 801317 3079562 lpg0733 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094769.1 799869 D 272624 CDS YP_094770.1 52840971 3078512 complement(801369..802979) 1 NC_002942.5 glutamine dependent NAD+ synthetase 802979 3078512 lpg0734 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine dependent NAD+ synthetase YP_094770.1 801369 R 272624 CDS YP_094771.1 52840972 3080588 803263..806529 1 NC_002942.5 DNA helicase SNF2/RAD54 family protein 806529 3080588 lpg0735 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA helicase SNF2/RAD54 family protein YP_094771.1 803263 D 272624 CDS YP_094772.1 52840973 3079684 complement(805297..805401) 1 NC_002942.5 SNF2 family helicase 805401 3079684 lpg0736 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SNF2 family helicase YP_094772.1 805297 R 272624 CDS YP_094773.1 52840974 3080254 806788..807222 1 NC_002942.5 signal peptide protein 807222 3080254 lpg0737 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide protein YP_094773.1 806788 D 272624 CDS YP_094774.1 52840975 3079537 807400..808782 1 NC_002942.5 replicative DNA helicase 808782 dnaB 3079537 dnaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 replicative DNA helicase YP_094774.1 807400 D 272624 CDS YP_094775.1 52840976 3077695 808784..809857 1 NC_002942.5 hypothetical protein 809857 3077695 lpg0739 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094775.1 808784 D 272624 CDS YP_094776.1 52840977 3079880 809930..810379 1 NC_002942.5 hypothetical protein 810379 omp 3079880 omp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094776.1 809930 D 272624 CDS YP_094777.1 52840978 3078950 810597..811121 1 NC_002942.5 identified by homology; hypothetical protein 811121 3078950 lpg0741 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094777.1 810597 D 272624 CDS YP_094778.1 52840979 3078198 811164..812417 1 NC_002942.5 hypothetical protein 812417 3078198 lpg0742 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094778.1 811164 D 272624 CDS YP_094779.1 52840980 3078403 812529..812825 1 NC_002942.5 hypothetical protein 812825 3078403 lpg0743 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094779.1 812529 D 272624 CDS YP_094780.1 52840981 3078402 812822..814372 1 NC_002942.5 diguanylate cyclase 814372 3078402 lpg0744 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 diguanylate cyclase YP_094780.1 812822 D 272624 CDS YP_094781.1 52840982 3080295 814524..815513 1 NC_002942.5 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 815513 3080295 lpg0745 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoyl synthase YP_094781.1 814524 D 272624 CDS YP_094782.1 52840983 3078615 complement(816831..818339) 1 NC_002942.5 IraAB 818339 3078615 lpg0746 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IraAB YP_094782.1 816831 R 272624 CDS YP_094783.1 52840984 3078595 complement(818378..819196) 1 NC_002942.5 small-molecule methyltransferase IraA 819196 3078595 lpg0747 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 small-molecule methyltransferase IraA YP_094783.1 818378 R 272624 CDS YP_094784.1 52840985 3080050 819356..820738 1 NC_002942.5 LPS biosynthesis protein, PseA-like 820738 3080050 lpg0748 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LPS biosynthesis protein, PseA-like YP_094784.1 819356 D 272624 CDS YP_094785.1 52840986 3078236 820735..821499 1 NC_002942.5 imidazole glycerol phosphate synthase subunit HisF 821499 hisF 3078236 hisF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazole glycerol phosphate synthase subunit HisF YP_094785.1 820735 D 272624 CDS YP_094786.1 52840987 3078779 821496..822137 1 NC_002942.5 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 822137 hisH 3078779 hisH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazole glycerol phosphate synthase subunit HisH YP_094786.1 821496 D 272624 CDS YP_094787.1 52840988 3078108 822150..822848 1 NC_002942.5 CMP-N-acetylneuraminic acid synthetase 822848 neuA 3078108 neuA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CMP-N-acetylneuraminic acid synthetase YP_094787.1 822150 D 272624 CDS YP_094788.1 52840989 3078679 822797..823867 1 NC_002942.5 N-acetylneuraminic acid synthase 823867 neuB 3078679 neuB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-acetylneuraminic acid synthase YP_094788.1 822797 D 272624 CDS YP_094789.1 52840990 3077796 823867..825000 1 NC_002942.5 N-acylglucosamine 2-epimerase 825000 3077796 lpg0753 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-acylglucosamine 2-epimerase YP_094789.1 823867 D 272624 CDS YP_094790.1 52840991 3078217 824990..825598 1 NC_002942.5 acetyltransferase 825598 3078217 lpg0754 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_094790.1 824990 D 272624 CDS YP_094791.1 52840992 3078511 825609..827111 1 NC_002942.5 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biosynthesis 827111 yvfE 3078511 yvfE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biosynthesis YP_094791.1 825609 D 272624 CDS YP_094792.1 52840993 3080596 827201..827764 1 NC_002942.5 dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC 827764 3080596 lpg0756 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC YP_094792.1 827201 D 272624 CDS YP_094793.1 52840994 3079941 827765..828649 1 NC_002942.5 dTDP-6-deoxy-L-mannose dehydrogenase RmlD 828649 3079941 lpg0757 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dTDP-6-deoxy-L-mannose dehydrogenase RmlD YP_094793.1 827765 D 272624 CDS YP_094794.1 52840995 3078133 828609..829688 1 NC_002942.5 dTDP-glucose 4,6-dehydratase RmlB 829688 rfbB 3078133 rfbB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dTDP-glucose 4,6-dehydratase RmlB YP_094794.1 828609 D 272624 CDS YP_094795.1 52840996 3080069 829724..831226 1 NC_002942.5 glucose-6-phosphate isomerase 831226 pgi 3080069 pgi Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucose-6-phosphate isomerase YP_094795.1 829724 D 272624 CDS YP_094796.1 52840997 3078757 831339..832256 1 NC_002942.5 glucose-1-phosphate thymidylyltransferase 832256 rfbA 3078757 rfbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucose-1-phosphate thymidylyltransferase YP_094796.1 831339 D 272624 CDS YP_094797.1 52840998 3080492 832277..833233 1 NC_002942.5 NAD dependent epimerase/dehydratase, UDP-glucose-4-epimerase 833233 3080492 lpg0761 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD dependent epimerase/dehydratase, UDP-glucose-4-epimerase YP_094797.1 832277 D 272624 CDS YP_094798.1 52840999 3077979 833217..834221 1 NC_002942.5 O-antigen initiating glycosyl transferase 834221 3077979 lpg0762 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-antigen initiating glycosyl transferase YP_094798.1 833217 D 272624 CDS YP_094799.1 52841000 3077974 834336..834578 1 NC_002942.5 hypothetical protein 834578 3077974 lpg0763 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094799.1 834336 D 272624 CDS YP_094800.1 52841001 3080389 834580..835104 1 NC_002942.5 hypothetical protein 835104 3080389 lpg0764 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094800.1 834580 D 272624 CDS YP_094801.1 52841002 3078012 complement(835678..837474) 1 NC_002942.5 hypothetical protein 837474 3078012 lpg0765 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094801.1 835678 R 272624 CDS YP_094802.1 52841003 3077661 complement(837477..838595) 1 NC_002942.5 hypothetical protein 838595 3077661 lpg0766 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094802.1 837477 R 272624 CDS YP_094803.1 52841004 3078293 complement(838606..839643) 1 NC_002942.5 hypothetical protein 839643 3078293 lpg0767 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094803.1 838606 R 272624 CDS YP_094804.1 52841005 3078022 complement(839597..840688) 1 NC_002942.5 spore coat polysaccharide biosynthesis protein E (NeuB) 840688 3078022 lpg0768 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spore coat polysaccharide biosynthesis protein E (NeuB) YP_094804.1 839597 R 272624 CDS YP_094805.1 52841006 3078370 complement(840701..841420) 1 NC_002942.5 hypothetical protein 841420 3078370 lpg0769 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094805.1 840701 R 272624 CDS YP_094806.1 52841007 3078339 841736..843253 1 NC_002942.5 hypothetical protein 843253 3078339 lpg0770 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094806.1 841736 D 272624 CDS YP_094807.1 52841008 3080152 843474..845168 1 NC_002942.5 hypothetical protein 845168 3080152 lpg0771 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094807.1 843474 D 272624 CDS YP_094808.1 52841009 3078118 845134..845985 1 NC_002942.5 ABC transporter 845985 rfbA 3078118 rfbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter YP_094808.1 845134 D 272624 CDS YP_094809.1 52841010 3079100 845982..847406 1 NC_002942.5 ABC transporter 847406 3079100 lpg0773 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter YP_094809.1 845982 D 272624 CDS YP_094810.1 52841011 3078483 847412..848560 1 NC_002942.5 hypothetical protein 848560 3078483 lpg0774 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094810.1 847412 D 272624 CDS YP_094811.1 52841012 3078665 complement(848574..849263) 1 NC_002942.5 glycosyl transferase 849263 3078665 lpg0775 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyl transferase YP_094811.1 848574 R 272624 CDS YP_094812.1 52841013 3078956 complement(849512..849700) 1 NC_002942.5 transposase 849700 3078956 lpg0776 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase YP_094812.1 849512 R 272624 CDS YP_094813.1 52841014 3080090 850246..851319 1 NC_002942.5 O-acetyltransferase 851319 3080090 lpg0777 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-acetyltransferase YP_094813.1 850246 D 272624 CDS YP_094814.1 52841015 3079433 complement(851432..852325) 1 NC_002942.5 glycosyl transferase 852325 3079433 lpg0778 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyl transferase YP_094814.1 851432 R 272624 CDS YP_094815.1 52841016 3080074 complement(852319..853338) 1 NC_002942.5 glycosyltransferase 853338 3080074 lpg0779 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyltransferase YP_094815.1 852319 R 272624 CDS YP_094816.1 52841017 3078264 853550..854257 1 NC_002942.5 metallo-beta-lactamase 854257 3078264 lpg0780 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metallo-beta-lactamase YP_094816.1 853550 D 272624 CDS YP_094817.1 52841018 3080104 854762..855010 1 NC_002942.5 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 855010 csrA-2 3080104 csrA-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbon storage regulator YP_094817.1 854762 D 272624 CDS YP_094818.1 52841019 3079547 complement(855136..857118) 1 NC_002942.5 O-antigen acetylase 857118 3079547 lpg0782 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-antigen acetylase YP_094818.1 855136 R 272624 CDS YP_094819.1 52841020 3078800 complement(857281..858276) 1 NC_002942.5 biotin synthetase 858276 birA 3078800 birA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biotin synthetase YP_094819.1 857281 R 272624 CDS YP_094820.1 52841021 3079895 complement(858280..859017) 1 NC_002942.5 phosphopantetheine-protein transferase 859017 3079895 lpg0784 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphopantetheine-protein transferase YP_094820.1 858280 R 272624 CDS YP_094821.1 52841022 3079629 859099..860052 1 NC_002942.5 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 860052 accA 3079629 accA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_094821.1 859099 D 272624 CDS YP_094822.1 52841023 3079263 860039..861340 1 NC_002942.5 cell cycle protein MesJ 861340 mesJ 3079263 mesJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell cycle protein MesJ YP_094822.1 860039 D 272624 CDS YP_094823.1 52841024 3078787 861690..862226 1 NC_002942.5 hypothetical protein 862226 3078787 lpg0787 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094823.1 861690 D 272624 CDS YP_094824.1 52841025 3078100 862556..863731 1 NC_002942.5 hypothetical protein 863731 3078100 lpg0788 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094824.1 862556 D 272624 CDS YP_094825.1 52841026 3078861 863728..865170 1 NC_002942.5 alginate O-acetyltransferase AlgI 865170 3078861 lpg0789 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alginate O-acetyltransferase AlgI YP_094825.1 863728 D 272624 CDS YP_094826.1 52841027 3080598 complement(865269..866645) 1 NC_002942.5 L-serine dehydratase 866645 sda-2 3080598 sda-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-serine dehydratase YP_094826.1 865269 R 272624 CDS YP_094827.1 52841028 3078495 866844..867551 1 NC_002942.5 macrophage infectivity potentiator (Mip) 867551 mip 3078495 mip Legionella pneumophila subsp. pneumophila str. Philadelphia 1 macrophage infectivity potentiator (Mip) YP_094827.1 866844 D 272624 CDS YP_094828.1 52841029 3078433 867705..868976 1 NC_002942.5 beta lactamase induction signal transducer AmpG 868976 ampG 3078433 ampG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 beta lactamase induction signal transducer AmpG YP_094828.1 867705 D 272624 CDS YP_094829.1 52841030 3079664 869088..869354 1 NC_002942.5 IS1400 transposase, transposase ORFA 869354 3079664 lpg0793 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS1400 transposase, transposase ORFA YP_094829.1 869088 D 272624 CDS YP_094830.1 52841031 3080601 869351..869698 1 NC_002942.5 ISI400 transposase B 869698 3080601 lpg0794 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISI400 transposase B YP_094830.1 869351 D 272624 CDS YP_094831.1 52841032 3078783 869667..870320 1 NC_002942.5 ISI400 transposase B 870320 3078783 lpg0795 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISI400 transposase B YP_094831.1 869667 D 272624 CDS YP_094832.1 52841033 3078218 870831..871481 1 NC_002942.5 hypothetical protein 871481 3078218 lpg0796 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094832.1 870831 D 272624 CDS YP_094833.1 52841034 3080102 871761..872147 1 NC_002942.5 hypothetical protein 872147 3080102 lpg0798 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094833.1 871761 D 272624 CDS YP_094834.1 52841035 3079480 complement(872251..873594) 1 NC_002942.5 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 873594 nadA 3079480 nadA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 quinolinate synthetase YP_094834.1 872251 R 272624 CDS YP_094835.1 52841036 3078590 complement(873669..875318) 1 NC_002942.5 L-aspartate oxidase 875318 nadB1 3078590 nadB1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-aspartate oxidase YP_094835.1 873669 R 272624 CDS YP_094836.1 52841037 3080284 complement(875315..876685) 1 NC_002942.5 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 876685 3080284 lpg0801 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylosuccinate lyase YP_094836.1 875315 R 272624 CDS YP_094837.1 52841038 3080375 876838..878541 1 NC_002942.5 sulfate transporter 878541 3080375 lpg0802 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfate transporter YP_094837.1 876838 D 272624 CDS YP_094838.1 52841039 3080533 complement(878744..880447) 1 NC_002942.5 acyl CoA dehydrogenase 880447 3080533 lpg0803 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA dehydrogenase YP_094838.1 878744 R 272624 CDS YP_094839.1 52841040 3079734 complement(880677..881675) 1 NC_002942.5 hypothetical protein 881675 3079734 lpg0804 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094839.1 880677 R 272624 CDS YP_094840.1 52841041 3079592 881900..884287 1 NC_002942.5 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 884287 3079592 lpg0805 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoenolpyruvate synthase YP_094840.1 881900 D 272624 CDS YP_094841.1 52841042 3078979 884529..885968 1 NC_002942.5 Na+/H+ antiporter 885968 3078979 lpg0806 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Na+/H+ antiporter YP_094841.1 884529 D 272624 CDS YP_094842.1 52841043 3080224 885965..886807 1 NC_002942.5 nicotinate-nucleotide pyrophosphorylase 886807 nadC 3080224 nadC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nicotinate-nucleotide pyrophosphorylase YP_094842.1 885965 D 272624 CDS YP_094843.1 52841044 3078544 886804..887895 1 NC_002942.5 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 887895 murG 3078544 murG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_094843.1 886804 D 272624 CDS YP_094844.1 52841045 3080132 887870..889285 1 NC_002942.5 hypothetical protein 889285 dapE 3080132 dapE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094844.1 887870 D 272624 CDS YP_094845.1 52841046 3079861 889377..889694 1 NC_002942.5 hypothetical protein 889694 3079861 lpg0810 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094845.1 889377 D 272624 CDS YP_094846.1 52841047 3077971 889884..890927 1 NC_002942.5 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 890927 mreB 3077971 mreB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rod shape-determining protein MreB YP_094846.1 889884 D 272624 CDS YP_094847.1 52841048 3078699 890905..891813 1 NC_002942.5 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 891813 mreC 3078699 mreC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rod shape-determining protein MreC YP_094847.1 890905 D 272624 CDS YP_094848.1 52841049 3080380 891810..892289 1 NC_002942.5 rod shape determining protein MreD 892289 mreD 3080380 mreD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rod shape determining protein MreD YP_094848.1 891810 D 272624 CDS YP_094849.1 52841050 3079413 complement(892225..892893) 1 NC_002942.5 pseudouridine synthase 892893 3079413 lpg0814 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pseudouridine synthase YP_094849.1 892225 R 272624 CDS YP_094850.1 52841051 3078174 893088..893786 1 NC_002942.5 hypothetical protein 893786 3078174 lpg0815 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094850.1 893088 D 272624 CDS YP_094851.1 52841052 3078982 893884..895152 1 NC_002942.5 isocitrate dehydrogenase 895152 icd 3078982 icd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 isocitrate dehydrogenase YP_094851.1 893884 D 272624 CDS YP_094852.1 52841053 3078623 895554..895889 1 NC_002942.5 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 895889 clpS 3078623 clpS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent Clp protease adaptor protein ClpS YP_094852.1 895554 D 272624 CDS YP_094853.1 52841054 3079665 895915..898188 1 NC_002942.5 ATP-binding protease component ClpA 898188 cl 3079665 cl Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-binding protease component ClpA YP_094853.1 895915 D 272624 CDS YP_094854.1 52841055 3079836 898489..899574 1 NC_002942.5 ORF2 transposase 899574 3079836 lpg0819 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ORF2 transposase YP_094854.1 898489 D 272624 CDS YP_094855.1 52841056 3078564 899600..899893 1 NC_002942.5 endonuclease 899893 3078564 lpg0820 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endonuclease YP_094855.1 899600 D 272624 CDS YP_094856.1 52841057 3080122 900049..900828 1 NC_002942.5 lipopolysaccharide biosynthesis glycosyltransferase 900828 3080122 lpg0821 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipopolysaccharide biosynthesis glycosyltransferase YP_094856.1 900049 D 272624 CDS YP_094857.1 52841058 3080611 900831..902081 1 NC_002942.5 O-antigen biosynthesis protein 902081 3080611 lpg0822 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-antigen biosynthesis protein YP_094857.1 900831 D 272624 CDS YP_094858.1 52841059 3079315 complement(902082..902456) 1 NC_002942.5 neurogenic locus notch protein-like protein 902456 3079315 lpg0823 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 neurogenic locus notch protein-like protein YP_094858.1 902082 R 272624 CDS YP_094859.1 52841060 3080482 complement(902587..903186) 1 NC_002942.5 rhomboid family protein 903186 3080482 lpg0824 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rhomboid family protein YP_094859.1 902587 R 272624 CDS YP_094860.1 52841061 3078034 complement(903183..904097) 1 NC_002942.5 M24/M37 family peptidase 904097 3078034 lpg0825 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 M24/M37 family peptidase YP_094860.1 903183 R 272624 CDS YP_094861.1 52841062 3079786 complement(904094..905425) 1 NC_002942.5 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 905425 xseA 3079786 xseA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 exodeoxyribonuclease VII large subunit YP_094861.1 904094 R 272624 CDS YP_094862.1 52841063 3080114 905575..907299 1 NC_002942.5 agglutination protein 907299 tolC 3080114 tolC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 agglutination protein YP_094862.1 905575 D 272624 CDS YP_094863.1 52841064 3080409 907250..907984 1 NC_002942.5 hypothetical protein 907984 3080409 lpg0828 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094863.1 907250 D 272624 CDS YP_094864.1 52841065 3077935 908000..909919 1 NC_002942.5 two component histidine kinase 909919 3077935 lpg0829 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component histidine kinase YP_094864.1 908000 D 272624 CDS YP_094865.1 52841066 3079657 910055..910780 1 NC_002942.5 hypothetical protein 910780 3079657 lpg0830 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094865.1 910055 D 272624 CDS YP_094866.1 52841067 3078316 910755..912098 1 NC_002942.5 flavin containing monooxygenae 912098 3078316 lpg0831 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flavin containing monooxygenae YP_094866.1 910755 D 272624 CDS YP_094867.1 52841068 3080460 complement(912191..913078) 1 NC_002942.5 oxidoreductase dehydrogenase, short chain 913078 3080460 lpg0832 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase dehydrogenase, short chain YP_094867.1 912191 R 272624 CDS YP_094868.1 52841069 3080501 complement(913515..914291) 1 NC_002942.5 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 914291 trpC 3080501 trpC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 indole-3-glycerol phosphate synthase YP_094868.1 913515 R 272624 CDS YP_094869.1 52841070 3078703 complement(914284..915318) 1 NC_002942.5 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 915318 trpD 3078703 trpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 anthranilate phosphoribosyltransferase YP_094869.1 914284 R 272624 CDS YP_094870.1 52841071 3079561 complement(915296..915874) 1 NC_002942.5 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 915874 pabA 3079561 pabA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 anthranilate synthase component II YP_094870.1 915296 R 272624 CDS YP_094871.1 52841072 3078053 complement(915908..916633) 1 NC_002942.5 ABC transporter ATP-binding protein 916633 3078053 lpg0836 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094871.1 915908 R 272624 CDS YP_094872.1 52841073 3080068 complement(916630..917139) 1 NC_002942.5 hypothetical protein 917139 3080068 lpg0837 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094872.1 916630 R 272624 CDS YP_094873.1 52841074 3079246 complement(917120..917689) 1 NC_002942.5 hypothetical protein 917689 3079246 lpg0838 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094873.1 917120 R 272624 CDS YP_094874.1 52841075 3079661 complement(917686..918237) 1 NC_002942.5 HAD superfamily hydrolase 918237 3079661 lpg0839 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HAD superfamily hydrolase YP_094874.1 917686 R 272624 CDS YP_094875.1 52841076 3080535 complement(918227..919189) 1 NC_002942.5 polysialic acid capsule expression protein 919189 3080535 lpg0840 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polysialic acid capsule expression protein YP_094875.1 918227 R 272624 CDS YP_094876.1 52841077 3080241 919557..920354 1 NC_002942.5 toluene tolerance ABC transporter ATP-binding protein Ttg2A 920354 3080241 lpg0841 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 toluene tolerance ABC transporter ATP-binding protein Ttg2A YP_094876.1 919557 D 272624 CDS YP_094877.1 52841078 3080354 920347..921129 1 NC_002942.5 toluene tolerance protein Ttg2B 921129 3080354 lpg0842 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 toluene tolerance protein Ttg2B YP_094877.1 920347 D 272624 CDS YP_094878.1 52841079 3080227 921130..921606 1 NC_002942.5 toluene tolerance protein Ttg2C 921606 3080227 lpg0843 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 toluene tolerance protein Ttg2C YP_094878.1 921130 D 272624 CDS YP_094879.1 52841080 3078777 921614..922222 1 NC_002942.5 signal peptide protein, toluene tolerance protein Ttg2D 922222 3078777 lpg0844 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide protein, toluene tolerance protein Ttg2D YP_094879.1 921614 D 272624 CDS YP_094880.1 52841081 3080531 922225..922506 1 NC_002942.5 hypothetical protein 922506 rsbV 3080531 rsbV Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094880.1 922225 D 272624 CDS YP_094881.1 52841082 3079870 922896..923141 1 NC_002942.5 BolA like regulator protein 923141 yrbA 3079870 yrbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 BolA like regulator protein YP_094881.1 922896 D 272624 CDS YP_094882.1 52841083 3078519 923134..924402 1 NC_002942.5 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 924402 murA 3078519 murA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_094882.1 923134 D 272624 CDS YP_094883.1 52841084 3080089 924399..925157 1 NC_002942.5 hydrolase-oxidase 925157 3080089 lpg0848 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrolase-oxidase YP_094883.1 924399 D 272624 CDS YP_094884.1 52841085 3080317 complement(925346..926023) 1 NC_002942.5 ABC transporter ATP-binding protein 926023 3080317 lpg0849 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_094884.1 925346 R 272624 CDS YP_094885.1 52841086 3079901 complement(926020..927270) 1 NC_002942.5 ABC transporter permease 927270 3079901 lpg0850 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_094885.1 926020 R 272624 CDS YP_094886.1 52841087 3077671 complement(927270..928286) 1 NC_002942.5 membrane fusion protein 928286 3077671 lpg0851 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane fusion protein YP_094886.1 927270 R 272624 CDS YP_094887.1 52841088 3078888 928676..929269 1 NC_002942.5 hypothetical protein 929269 3078888 lpg0852 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094887.1 928676 D 272624 CDS YP_094888.1 52841089 3078537 929465..930880 1 NC_002942.5 transcriptional regulator FleQ 930880 fleQ 3078537 fleQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator FleQ YP_094888.1 929465 D 272624 CDS YP_094889.1 52841090 3079321 complement(930924..931205) 1 NC_002942.5 hypothetical protein 931205 3079321 lpg0854 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094889.1 930924 R 272624 CDS YP_094890.2 229270458 3079616 complement(931428..932366) 1 NC_002942.5 SohB; periplasmic protein; member of the peptidase S49 family; protease 932366 3079616 lpg0855 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protease YP_094890.2 931428 R 272624 CDS YP_094891.2 229270457 3079879 932511..933113 1 NC_002942.5 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 933113 ccmA 3079879 ccmA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c biogenesis protein CcmA YP_094891.2 932511 D 272624 CDS YP_094892.1 52841093 3078532 933110..933790 1 NC_002942.5 heme exporter protein CcmB 933790 ccmB 3078532 ccmB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heme exporter protein CcmB YP_094892.1 933110 D 272624 CDS YP_094893.1 52841094 3078651 933968..934759 1 NC_002942.5 heme exporter protein CcmC 934759 ccmC 3078651 ccmC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heme exporter protein CcmC YP_094893.1 933968 D 272624 CDS YP_094894.1 52841095 3080337 934770..934901 1 NC_002942.5 heme exporter protein CcmD 934901 3080337 lpg0859 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heme exporter protein CcmD YP_094894.1 934770 D 272624 CDS YP_094895.1 52841096 3079247 934907..935338 1 NC_002942.5 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome C biogenesis protein CcmE 935338 ccmE 3079247 ccmE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome C biogenesis protein CcmE YP_094895.1 934907 D 272624 CDS YP_094896.1 52841097 3078964 935335..937287 1 NC_002942.5 cytochrome C biogenesis protein CcmF 937287 ccmF 3078964 ccmF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome C biogenesis protein CcmF YP_094896.1 935335 D 272624 CDS YP_094897.1 52841098 3078963 937284..937817 1 NC_002942.5 conserved gene, previously annotated as cytochrome c biogenesis protein CcmG in Legionella pneumophila; cytochrome C biogenesis protein 937817 dsbE 3078963 dsbE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome C biogenesis protein YP_094897.1 937284 D 272624 CDS YP_094898.1 52841099 3078363 937817..938218 1 NC_002942.5 cytochrome C biogenesis protein CcmH 938218 3078363 lpg0863 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome C biogenesis protein CcmH YP_094898.1 937817 D 272624 CDS YP_094899.1 52841100 3079912 938166..938897 1 NC_002942.5 cytochrome c type biogenesis protein CcmH 938897 cycH 3079912 cycH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c type biogenesis protein CcmH YP_094899.1 938166 D 272624 CDS YP_094900.1 52841101 3078298 939146..939550 1 NC_002942.5 conserved gene, previously annotated as cytochrome c type biogenesis protein CcmH in Legionella pneumophila, perhaps by artifactual extension of previous protein; cytochrome c type biogenesis protein CycH 939550 3078298 lpg0865 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c type biogenesis protein CycH YP_094900.1 939146 D 272624 CDS YP_094901.1 52841102 3080451 complement(939745..940296) 1 NC_002942.5 3-methyladenine DNA glycosylase 940296 3080451 lpg0866 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-methyladenine DNA glycosylase YP_094901.1 939745 R 272624 CDS YP_094902.1 52841103 3079696 complement(940306..942132) 1 NC_002942.5 ATP-dependent DNA helicase RecQ 942132 recQ 3079696 recQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent DNA helicase RecQ YP_094902.1 940306 R 272624 CDS YP_094903.1 52841104 3078562 942246..943400 1 NC_002942.5 acyl CoA dehydrogenase 943400 3078562 lpg0868 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA dehydrogenase YP_094903.1 942246 D 272624 CDS YP_094904.1 52841105 3079038 943414..944193 1 NC_002942.5 3-hydroxyisobutyryl-CoA hydrolase 944193 3079038 lpg0869 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxyisobutyryl-CoA hydrolase YP_094904.1 943414 D 272624 CDS YP_094905.1 52841106 3079189 944196..945254 1 NC_002942.5 3-hydroxyisobutyryl-CoA hydrolase 945254 3079189 lpg0870 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxyisobutyryl-CoA hydrolase YP_094905.1 944196 D 272624 CDS YP_094906.1 52841107 3078551 complement(945420..946286) 1 NC_002942.5 hypothetical protein 946286 3078551 lpg0871 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094906.1 945420 R 272624 CDS YP_094907.1 52841108 3079803 946510..948090 1 NC_002942.5 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 948090 prfC 3079803 prfC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide chain release factor 3 YP_094907.1 946510 D 272624 CDS YP_094908.1 52841109 3079952 complement(948156..948581) 1 NC_002942.5 hypothetical protein 948581 3079952 lpg0873 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094908.1 948156 R 272624 CDS YP_094909.1 52841110 3079102 complement(948674..950095) 1 NC_002942.5 NAD(P) transhydrogenase subunit beta 950095 pntB 3079102 pntB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD(P) transhydrogenase subunit beta YP_094909.1 948674 R 272624 CDS YP_094910.1 52841111 3080261 complement(950095..950391) 1 NC_002942.5 NAD(P) transhydrogenase subunit beta 950391 pntAb2 3080261 pntAb2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD(P) transhydrogenase subunit beta YP_094910.1 950095 R 272624 CDS YP_094911.1 52841112 3079638 complement(950384..951517) 1 NC_002942.5 pyridine nucleotide transhydrogenase subunit alpha 951517 pntAa 3079638 pntAa Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridine nucleotide transhydrogenase subunit alpha YP_094911.1 950384 R 272624 CDS YP_094912.1 52841113 3079174 complement(951911..952465) 1 NC_002942.5 transporter 952465 3079174 lpg0877 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter YP_094912.1 951911 R 272624 CDS YP_094913.1 52841114 3079697 complement(952719..953018) 1 NC_002942.5 hypothetical protein 953018 3079697 lpg0878 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094913.1 952719 R 272624 CDS YP_094914.1 52841115 3080084 953282..954424 1 NC_002942.5 two component response regulator protein 954424 3080084 lpg0879 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component response regulator protein YP_094914.1 953282 D 272624 CDS YP_094915.1 52841116 3078258 complement(954486..955127) 1 NC_002942.5 hypothetical protein 955127 3078258 lpg0880 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094915.1 954486 R 272624 CDS YP_094916.1 52841117 3079936 955610..956044 1 NC_002942.5 hypothetical protein 956044 3079936 lpg0882 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094916.1 955610 D 272624 CDS YP_094917.1 52841118 3079158 956168..956614 1 NC_002942.5 hypothetical protein 956614 3079158 lpg0883 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094917.1 956168 D 272624 CDS YP_094918.1 52841119 3079009 complement(956471..956806) 1 NC_002942.5 hypothetical protein 956806 3079009 lpg0884 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094918.1 956471 R 272624 CDS YP_094919.1 52841120 3078966 956741..957817 1 NC_002942.5 glycosyl hydrolase 957817 3078966 lpg0885 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyl hydrolase YP_094919.1 956741 D 272624 CDS YP_094920.1 52841121 3080094 958332..959612 1 NC_002942.5 hypothetical protein 959612 3080094 lpg0886 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094920.1 958332 D 272624 CDS YP_094921.1 52841122 3078461 complement(959936..961069) 1 NC_002942.5 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 961069 dapE 3078461 dapE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinyl-diaminopimelate desuccinylase YP_094921.1 959936 R 272624 CDS YP_094922.1 52841123 3080305 complement(961062..961892) 1 NC_002942.5 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 961892 dapD 3080305 dapD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_094922.1 961062 R 272624 CDS YP_094923.1 52841124 3079505 complement(961896..962789) 1 NC_002942.5 acyltransferase 962789 3079505 lpg0889 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyltransferase YP_094923.1 961896 R 272624 CDS YP_094924.1 52841125 3079639 complement(962856..964007) 1 NC_002942.5 cystathionine beta-lyase 964007 metC 3079639 metC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cystathionine beta-lyase YP_094924.1 962856 R 272624 CDS YP_094925.1 52841126 3080061 964156..966471 1 NC_002942.5 sensory box protein 966471 3080061 lpg0891 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_094925.1 964156 D 272624 CDS YP_094926.1 52841127 3080099 966773..968122 1 NC_002942.5 kynurenine 3-monooxygenase 968122 3080099 lpg0892 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 kynurenine 3-monooxygenase YP_094926.1 966773 D 272624 CDS YP_094927.1 52841128 3080379 968328..969092 1 NC_002942.5 hypothetical protein 969092 3080379 lpg0893 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094927.1 968328 D 272624 CDS YP_094928.1 52841129 3078550 969049..970419 1 NC_002942.5 cytokinin oxidase 970419 3078550 lpg0894 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytokinin oxidase YP_094928.1 969049 D 272624 CDS YP_094929.1 52841130 3080603 970769..971278 1 NC_002942.5 hypothetical protein 971278 3080603 lpg0895 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094929.1 970769 D 272624 CDS YP_094930.1 52841131 3079444 971284..971661 1 NC_002942.5 hypothetical protein 971661 3079444 lpg0896 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094930.1 971284 D 272624 CDS YP_094931.1 52841132 3079623 complement(971743..972702) 1 NC_002942.5 Na/Ca antiporter 972702 3079623 lpg0897 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Na/Ca antiporter YP_094931.1 971743 R 272624 CDS YP_094932.1 52841133 3079347 complement(972975..973706) 1 NC_002942.5 hypothetical protein 973706 3079347 lpg0898 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094932.1 972975 R 272624 CDS YP_094933.1 52841134 3079550 complement(973918..974985) 1 NC_002942.5 A/G-specific adenine glycosylase 974985 3079550 lpg0899 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 A/G-specific adenine glycosylase YP_094933.1 973918 R 272624 CDS YP_094934.1 52841135 3079857 complement(974982..976550) 1 NC_002942.5 hypothetical protein 976550 3079857 lpg0900 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094934.1 974982 R 272624 CDS YP_094935.1 52841136 3079701 976937..977593 1 NC_002942.5 hypothetical protein 977593 3079701 lpg0901 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094935.1 976937 D 272624 CDS YP_094936.1 52841137 3078724 977598..978500 1 NC_002942.5 hypothetical protein 978500 3078724 lpg0902 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094936.1 977598 D 272624 CDS YP_094937.1 52841138 3080280 979029..980120 1 NC_002942.5 DegP protease 980120 3080280 lpg0903 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DegP protease YP_094937.1 979029 D 272624 CDS YP_094938.1 52841139 3080578 980240..980785 1 NC_002942.5 isochorismatase superfamily hydrolase 980785 3080578 lpg0904 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 isochorismatase superfamily hydrolase YP_094938.1 980240 D 272624 CDS YP_094939.1 52841140 3078061 980995..981738 1 NC_002942.5 3-oxoacyl-ACP reductase 981738 3078061 lpg0905 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP reductase YP_094939.1 980995 D 272624 CDS YP_094940.1 52841141 3079044 complement(981795..982292) 1 NC_002942.5 flagellar biosynthesis/type III secretory pathway chaperone 982292 3079044 lpg0906 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis/type III secretory pathway chaperone YP_094940.1 981795 R 272624 CDS YP_094941.1 52841142 3078168 complement(982309..982629) 1 NC_002942.5 negative regulator of flagellin synthesis 982629 3078168 lpg0907 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 negative regulator of flagellin synthesis YP_094941.1 982309 R 272624 CDS YP_094942.1 52841143 3078986 complement(982720..983421) 1 NC_002942.5 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 983421 flgA 3078986 flgA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body P-ring biosynthesis protein FlgA YP_094942.1 982720 R 272624 CDS YP_094943.1 52841144 3080585 983508..983915 1 NC_002942.5 cytochrome c5 983915 3080585 lpg0909 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c5 YP_094943.1 983508 D 272624 CDS YP_094944.1 52841145 3079626 983992..984549 1 NC_002942.5 enhanced entry protein EnhA 984549 enhA 3079626 enhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhA YP_094944.1 983992 D 272624 CDS YP_094945.1 52841146 3080447 984836..985606 1 NC_002942.5 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 985606 3080447 lpg0911 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pantothenate kinase YP_094945.1 984836 D 272624 CDS YP_094946.1 52841147 3078642 985895..986005 1 NC_002942.5 hypothetical protein 986005 3078642 lpg0912 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094946.1 985895 D 272624 CDS YP_094947.1 52841148 3080367 986179..986682 1 NC_002942.5 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 986682 3080367 lpg0913 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein MraZ YP_094947.1 986179 D 272624 CDS YP_094948.1 52841149 3080318 986616..987620 1 NC_002942.5 S-adenosyl-methyltransferase MraW 987620 mraW 3080318 mraW Legionella pneumophila subsp. pneumophila str. Philadelphia 1 S-adenosyl-methyltransferase MraW YP_094948.1 986616 D 272624 CDS YP_094949.1 52841150 3080290 987677..987955 1 NC_002942.5 cell division transmembrane protein FtsL 987955 3080290 lpg0915 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division transmembrane protein FtsL YP_094949.1 987677 D 272624 CDS YP_094950.1 52841151 3080119 988336..989997 1 NC_002942.5 peptidoglycan synthetase FtsI 989997 pbpB 3080119 pbpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidoglycan synthetase FtsI YP_094950.1 988336 D 272624 CDS YP_094951.1 52841152 3080457 990018..991469 1 NC_002942.5 UDP-N-acetylmuramyl-tripeptide synthetase MurE 991469 murE 3080457 murE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramyl-tripeptide synthetase MurE YP_094951.1 990018 D 272624 CDS YP_094952.1 52841153 3078789 complement(991514..992566) 1 NC_002942.5 erythronate-4-phosphate dehydrogenase 992566 3078789 lpg0918 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 erythronate-4-phosphate dehydrogenase YP_094952.1 991514 R 272624 CDS YP_094953.1 52841154 3079493 complement(992563..993222) 1 NC_002942.5 transmembrane protein 993222 3079493 lpg0919 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_094953.1 992563 R 272624 CDS YP_094954.1 52841155 3079954 993471..994118 1 NC_002942.5 phosphatidylglycerophosphatase B 994118 3079954 lpg0920 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidylglycerophosphatase B YP_094954.1 993471 D 272624 CDS YP_094955.1 52841156 3079382 994158..995402 1 NC_002942.5 hypothetical protein 995402 3079382 lpg0921 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094955.1 994158 D 272624 CDS YP_094956.1 52841157 3080191 995810..996559 1 NC_002942.5 electron transfer flavoprotein subunit beta 996559 etfB 3080191 etfB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 electron transfer flavoprotein subunit beta YP_094956.1 995810 D 272624 CDS YP_094957.1 52841158 3078397 996573..997511 1 NC_002942.5 electron transfer flavoprotein subunit alpha 997511 etfA-2 3078397 etfA-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 electron transfer flavoprotein subunit alpha YP_094957.1 996573 D 272624 CDS YP_094958.1 52841159 3080115 997523..998644 1 NC_002942.5 alanine dehydrogenase 998644 ald 3080115 ald Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alanine dehydrogenase YP_094958.1 997523 D 272624 CDS YP_094959.1 52841160 3079236 complement(998716..1001100) 1 NC_002942.5 penicillin binding protein 1A 1001100 ponA 3079236 ponA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 penicillin binding protein 1A YP_094959.1 998716 R 272624 CDS YP_094960.1 52841161 3078825 complement(1001252..1002262) 1 NC_002942.5 hypothetical protein 1002262 3078825 lpg0926 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094960.1 1001252 R 272624 CDS YP_094961.1 52841162 3077807 1002679..1003743 1 NC_002942.5 type IV pilus assembly protein PilM 1003743 pilM 3077807 pilM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilus assembly protein PilM YP_094961.1 1002679 D 272624 CDS YP_094962.1 52841163 3078493 1003747..1004295 1 NC_002942.5 type IV pilus biogenesis protein PilN 1004295 pilN 3078493 pilN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilus biogenesis protein PilN YP_094962.1 1003747 D 272624 CDS YP_094963.1 52841164 3078444 1004273..1004908 1 NC_002942.5 type IV pilus biogenesis protein PilO 1004908 pilO 3078444 pilO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilus biogenesis protein PilO YP_094963.1 1004273 D 272624 CDS YP_094964.1 52841165 3077874 1004905..1005492 1 NC_002942.5 type IV pilus biogenesis protein PilP 1005492 pilP 3077874 pilP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilus biogenesis protein PilP YP_094964.1 1004905 D 272624 CDS YP_094965.1 52841166 3080247 1005496..1007592 1 NC_002942.5 type IV pilus biogenesis protein PilQ 1007592 pilQ 3080247 pilQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type IV pilus biogenesis protein PilQ YP_094965.1 1005496 D 272624 CDS YP_094966.1 52841167 3078713 1008038..1008565 1 NC_002942.5 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 1008565 aroK 3078713 aroK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 shikimate kinase I YP_094966.1 1008038 D 272624 CDS YP_094967.1 52841168 3079494 1008552..1009661 1 NC_002942.5 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1009661 aroB 3079494 aroB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-dehydroquinate synthase YP_094967.1 1008552 D 272624 CDS YP_094968.1 52841169 3079137 1009658..1011109 1 NC_002942.5 DamX-like protein 1011109 3079137 lpg0934 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DamX-like protein YP_094968.1 1009658 D 272624 CDS YP_094969.1 52841170 3080626 1011218..1011649 1 NC_002942.5 universal stress protein A (UspA) 1011649 3080626 lpg0935 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 universal stress protein A (UspA) YP_094969.1 1011218 D 272624 CDS YP_094970.1 52841171 3079868 1011773..1012759 1 NC_002942.5 riboflavin biosynthesis RibF 1012759 ribF 3079868 ribF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 riboflavin biosynthesis RibF YP_094970.1 1011773 D 272624 CDS YP_094971.1 52841172 3078903 1012872..1015667 1 NC_002942.5 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1015667 ileS 3078903 ileS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 isoleucyl-tRNA synthetase YP_094971.1 1012872 D 272624 CDS YP_094972.1 52841173 3077888 1015763..1016128 1 NC_002942.5 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1016128 lspA 3077888 lspA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein signal peptidase YP_094972.1 1015763 D 272624 CDS YP_094973.1 52841174 3078726 complement(1016427..1016990) 1 NC_002942.5 2-dehydro-3-deoxyphosphooctonate aldolase 1016990 eda 3078726 eda Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-dehydro-3-deoxyphosphooctonate aldolase YP_094973.1 1016427 R 272624 CDS YP_094974.1 52841175 3078760 complement(1017170..1019359) 1 NC_002942.5 LidA 1019359 3078760 lpg0940 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LidA YP_094974.1 1017170 R 272624 CDS YP_094975.1 52841176 3077656 complement(1019601..1022726) 1 NC_002942.5 hypothetical protein 1022726 3077656 lpg0941 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094975.1 1019601 R 272624 CDS YP_094976.1 52841177 3079796 1022940..1023875 1 NC_002942.5 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1023875 era 3079796 era Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP-binding protein Era YP_094976.1 1022940 D 272624 CDS YP_094977.1 52841178 3078579 1023865..1024554 1 NC_002942.5 DNA repair protein RecO 1024554 recO 3078579 recO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA repair protein RecO YP_094977.1 1023865 D 272624 CDS YP_094978.1 52841179 3078627 complement(1024610..1025785) 1 NC_002942.5 hypothetical protein 1025785 3078627 lpg0944 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094978.1 1024610 R 272624 CDS YP_094979.1 52841180 3078525 complement(1025948..1026838) 1 NC_002942.5 leucine-rich repeat-containing protein; Gala protein type 1, 3 or 4 1026838 legL1 3078525 legL1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Gala protein type 1, 3 or 4 YP_094979.1 1025948 R 272624 CDS YP_094980.1 52841181 3079301 1027067..1027873 1 NC_002942.5 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1027873 pdxJ 3079301 pdxJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridoxine 5'-phosphate synthase YP_094980.1 1027067 D 272624 CDS YP_094981.1 52841182 3078594 1027860..1029677 1 NC_002942.5 2-oxoglutarate ferredoxin oxidoreductase subunit alpha 1029677 3078594 lpg0947 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-oxoglutarate ferredoxin oxidoreductase subunit alpha YP_094981.1 1027860 D 272624 CDS YP_094982.1 52841183 3078008 1029637..1030629 1 NC_002942.5 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1030629 korB 3078008 korB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_094982.1 1029637 D 272624 CDS YP_094983.1 52841184 3077930 complement(1030958..1031632) 1 NC_002942.5 carrier/transport protein 1031632 3077930 lpg0949 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carrier/transport protein YP_094983.1 1030958 R 272624 CDS YP_094984.1 52841185 3078229 1031851..1032657 1 NC_002942.5 nitrilase 1032657 3078229 lpg0950 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitrilase YP_094984.1 1031851 D 272624 CDS YP_094985.1 52841186 3077927 1032669..1034111 1 NC_002942.5 TldD protein 1034111 tldD 3077927 tldD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TldD protein YP_094985.1 1032669 D 272624 CDS YP_094986.1 52841187 3077911 1034157..1035035 1 NC_002942.5 phosphoesterase 1035035 ychK 3077911 ychK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoesterase YP_094986.1 1034157 D 272624 CDS YP_094987.1 52841188 3078451 1035062..1036729 1 NC_002942.5 AMP-binding protein 1036729 3078451 lpg0953 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AMP-binding protein YP_094987.1 1035062 D 272624 CDS YP_094988.1 52841189 3079457 complement(1036708..1040169) 1 NC_002942.5 transcription repair coupling factor 1040169 mfd 3079457 mfd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription repair coupling factor YP_094988.1 1036708 R 272624 CDS YP_094989.1 52841190 3080313 complement(1040246..1041508) 1 NC_002942.5 hypothetical protein 1041508 3080313 lpg0955 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094989.1 1040246 R 272624 CDS YP_094990.1 52841191 3077966 complement(1041512..1042690) 1 NC_002942.5 hypothetical protein 1042690 3077966 lpg0956 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094990.1 1041512 R 272624 CDS YP_094991.1 52841192 3078462 complement(1042687..1043592) 1 NC_002942.5 hypothetical protein 1043592 3078462 lpg0957 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094991.1 1042687 R 272624 CDS YP_094992.1 52841193 3078179 1043779..1045830 1 NC_002942.5 DNA ligase 1045830 lig 3078179 lig Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA ligase YP_094992.1 1043779 D 272624 CDS YP_094993.1 52841194 3078355 1045932..1048115 1 NC_002942.5 ABC transporter substrate-binding protein 1048115 hbpA 3078355 hbpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter substrate-binding protein YP_094993.1 1045932 D 272624 CDS YP_094994.1 52841195 3077905 1048112..1049089 1 NC_002942.5 peptide ABC transporter permease 1049089 3077905 lpg0960 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide ABC transporter permease YP_094994.1 1048112 D 272624 CDS YP_094995.1 52841196 3080529 1049086..1050459 1 NC_002942.5 peptide ABC transporter permease 1050459 3080529 lpg0961 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide ABC transporter permease YP_094995.1 1049086 D 272624 CDS YP_094996.1 52841197 3077804 1050534..1053980 1 NC_002942.5 DNA polymerase III subunit alpha 1053980 dnaE 3077804 dnaE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III subunit alpha YP_094996.1 1050534 D 272624 CDS YP_094997.1 52841198 3080043 complement(1054066..1055307) 1 NC_002942.5 hypothetical protein 1055307 3080043 lpg0963 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_094997.1 1054066 R 272624 CDS YP_094998.1 52841199 3078353 1055637..1056521 1 NC_002942.5 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 1056521 3078353 lpg0964 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_094998.1 1055637 D 272624 CDS YP_094999.1 52841200 3078805 1056482..1058029 1 NC_002942.5 protein LphB 1058029 3078805 lpg0965 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LphB YP_094999.1 1056482 D 272624 CDS YP_095000.1 52841201 3079985 1058084..1059961 1 NC_002942.5 nucleoside-diphosphate sugar epimerases 1059961 3079985 lpg0966 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleoside-diphosphate sugar epimerases YP_095000.1 1058084 D 272624 CDS YP_095001.1 52841202 3080602 complement(1060107..1060700) 1 NC_002942.5 hypothetical protein 1060700 3080602 lpg0967 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095001.1 1060107 R 272624 CDS YP_095002.1 52841203 3080563 complement(1061065..1062786) 1 NC_002942.5 hypothetical protein 1062786 3080563 lpg0968 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095002.1 1061065 R 272624 CDS YP_095003.1 52841204 3079963 1063227..1063967 1 NC_002942.5 hypothetical protein 1063967 3079963 lpg0969 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095003.1 1063227 D 272624 CDS YP_095004.1 52841205 3080431 complement(1064069..1065532) 1 NC_002942.5 amino acid permease 1065532 3080431 lpg0970 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid permease YP_095004.1 1064069 R 272624 CDS YP_095005.1 52841206 3078093 1065913..1067058 1 NC_002942.5 ecto-ATP diphosphohydrolase II 1067058 3078093 lpg0971 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ecto-ATP diphosphohydrolase II YP_095005.1 1065913 D 272624 CDS YP_095006.1 52841207 3080480 1067616..1068374 1 NC_002942.5 hypothetical protein 1068374 3080480 lpg0973 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095006.1 1067616 D 272624 CDS YP_095007.1 52841208 3079267 1068446..1069525 1 NC_002942.5 hypothetical protein 1069525 3079267 lpg0974 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095007.1 1068446 D 272624 CDS YP_095008.1 52841209 3077894 complement(1069545..1070384) 1 NC_002942.5 transmembrane protein 1070384 3077894 lpg0975 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095008.1 1069545 R 272624 CDS YP_095009.1 52841210 3080323 complement(1070520..1071026) 1 NC_002942.5 antirestriction protein 1071026 3080323 lpg0976 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 antirestriction protein YP_095009.1 1070520 R 272624 CDS YP_095010.1 52841211 3080557 complement(1071092..1071514) 1 NC_002942.5 ssDNA-binding protein 1071514 3080557 lpg0977 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ssDNA-binding protein YP_095010.1 1071092 R 272624 CDS YP_095011.1 52841212 3077959 complement(1071615..1071863) 1 NC_002942.5 hypothetical protein 1071863 3077959 lpg0978 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095011.1 1071615 R 272624 CDS YP_095012.1 52841213 3079583 1072220..1072759 1 NC_002942.5 aminoglycoside N(6')acetyltransferase 1072759 aacA4 3079583 aacA4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminoglycoside N(6')acetyltransferase YP_095012.1 1072220 D 272624 CDS YP_095013.1 52841214 3078268 complement(1072751..1073674) 1 NC_002942.5 integrase 1073674 3078268 lpg0980 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 integrase YP_095013.1 1072751 R 272624 CDS YP_095014.1 52841215 3079462 complement(1073643..1074452) 1 NC_002942.5 hypothetical protein 1074452 3079462 lpg0981 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095014.1 1073643 R 272624 CDS YP_095015.1 52841216 3080075 1075236..1076102 1 NC_002942.5 hypothetical protein 1076102 3080075 lpg0982 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095015.1 1075236 D 272624 CDS YP_095016.1 52841217 3079900 complement(1076121..1078067) 1 NC_002942.5 conjugative coupling factor TraD 1078067 3079900 lpg0983 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative coupling factor TraD YP_095016.1 1076121 R 272624 CDS YP_095017.1 52841218 3079866 complement(1078064..1078393) 1 NC_002942.5 hypothetical protein 1078393 3079866 lpg0984 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095017.1 1078064 R 272624 CDS YP_095018.1 52841219 3079818 1078408..1078581 1 NC_002942.5 hypothetical protein 1078581 3079818 lpg0985 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095018.1 1078408 D 272624 CDS YP_095019.1 52841220 3080222 complement(1078587..1080140) 1 NC_002942.5 hypothetical protein 1080140 3080222 lpg0986 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095019.1 1078587 R 272624 CDS YP_095020.1 52841221 3080422 complement(1080143..1081510) 1 NC_002942.5 Tfp pilus assembly, pilus retraction ATPase PilT 1081510 3080422 lpg0987 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Tfp pilus assembly, pilus retraction ATPase PilT YP_095020.1 1080143 R 272624 CDS YP_095021.1 52841222 3079089 complement(1081520..1082494) 1 NC_002942.5 hypothetical protein 1082494 3079089 lpg0988 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095021.1 1081520 R 272624 CDS YP_095022.1 52841223 3078384 complement(1082487..1085240) 1 NC_002942.5 Type IV secretory protein VirB4 components 1085240 3078384 lpg0989 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Type IV secretory protein VirB4 components YP_095022.1 1082487 R 272624 CDS YP_095023.1 52841224 3079921 complement(1085247..1085570) 1 NC_002942.5 hypothetical protein 1085570 3079921 lpg0990 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095023.1 1085247 R 272624 CDS YP_095024.1 52841225 3079200 complement(1085551..1086810) 1 NC_002942.5 exported membrane protein 1086810 3079200 lpg0991 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 exported membrane protein YP_095024.1 1085551 R 272624 CDS YP_095025.1 52841226 3079035 complement(1086807..1087643) 1 NC_002942.5 hypothetical protein 1087643 3079035 lpg0992 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095025.1 1086807 R 272624 CDS YP_095026.1 52841227 3079080 complement(1087570..1088226) 1 NC_002942.5 hypothetical protein 1088226 3079080 lpg0993 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095026.1 1087570 R 272624 CDS YP_095027.1 52841228 3079882 complement(1088219..1088581) 1 NC_002942.5 hypothetical protein 1088581 3079882 lpg0994 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095027.1 1088219 R 272624 CDS YP_095028.1 52841229 3080515 complement(1088593..1088958) 1 NC_002942.5 hypothetical protein 1088958 3080515 lpg0995 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095028.1 1088593 R 272624 CDS YP_095029.1 52841230 3079426 complement(1088955..1089221) 1 NC_002942.5 hypothetical protein 1089221 3079426 lpg0996 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095029.1 1088955 R 272624 CDS YP_095030.1 52841231 3079026 complement(1089221..1089547) 1 NC_002942.5 hypothetical protein 1089547 3079026 lpg0997 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095030.1 1089221 R 272624 CDS YP_095031.1 52841232 3079764 complement(1089557..1090189) 1 NC_002942.5 hypothetical protein 1090189 3079764 lpg0998 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095031.1 1089557 R 272624 CDS YP_095032.1 52841233 3079097 complement(1090180..1090611) 1 NC_002942.5 hypothetical protein 1090611 3079097 lpg0999 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095032.1 1090180 R 272624 CDS YP_095033.1 52841234 3079829 complement(1090611..1091432) 1 NC_002942.5 hypothetical protein 1091432 3079829 lpg1000 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095033.1 1090611 R 272624 CDS YP_095034.1 52841235 3079024 complement(1091425..1092012) 1 NC_002942.5 hypothetical protein 1092012 3079024 lpg1001 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095034.1 1091425 R 272624 CDS YP_095035.1 52841236 3079337 complement(1092009..1092422) 1 NC_002942.5 hypothetical protein 1092422 3079337 lpg1002 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095035.1 1092009 R 272624 CDS YP_095036.1 52841237 3079409 complement(1092431..1092631) 1 NC_002942.5 carbon storage regulator 1092631 csrA-2 3079409 csrA-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbon storage regulator YP_095036.1 1092431 R 272624 CDS YP_095037.1 52841238 3078255 complement(1092625..1092978) 1 NC_002942.5 hypothetical protein 1092978 3078255 lpg1004 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095037.1 1092625 R 272624 CDS YP_095038.1 52841239 3080355 complement(1092995..1093906) 1 NC_002942.5 protein LvrA 1093906 lvrA 3080355 lvrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrA YP_095038.1 1092995 R 272624 CDS YP_095039.1 52841240 3080572 1094785..1096029 1 NC_002942.5 cobalt/zinc/cadmium efflux RND transporter outer membrane protein 1096029 3080572 lpg1006 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cobalt/zinc/cadmium efflux RND transporter outer membrane protein YP_095039.1 1094785 D 272624 CDS YP_095040.1 52841241 3079459 1096026..1097282 1 NC_002942.5 cation efflux system HelB 1097282 3079459 lpg1007 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation efflux system HelB YP_095040.1 1096026 D 272624 CDS YP_095041.1 52841242 3079534 1097289..1100441 1 NC_002942.5 cobalt/zinc/cadmium efflux RND transporter permease HelA 1100441 3079534 lpg1008 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cobalt/zinc/cadmium efflux RND transporter permease HelA YP_095041.1 1097289 D 272624 CDS YP_095042.1 52841243 3079095 1100463..1102652 1 NC_002942.5 cadmium translocating P-type ATPase CadA 1102652 cadA-1 3079095 cadA-1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cadmium translocating P-type ATPase CadA YP_095042.1 1100463 D 272624 CDS YP_095043.1 52841244 3079656 1103657..1105564 1 NC_002942.5 cadmium efflux ATPase 1105564 3079656 lpg1010 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cadmium efflux ATPase YP_095043.1 1103657 D 272624 CDS YP_095044.1 52841245 3079362 complement(1105579..1105974) 1 NC_002942.5 hypothetical protein 1105974 3079362 lpg1011 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095044.1 1105579 R 272624 CDS YP_095045.1 52841246 3079198 complement(1106003..1106200) 1 NC_002942.5 hypothetical protein 1106200 3079198 lpg1012 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095045.1 1106003 R 272624 CDS YP_095046.1 52841247 3077865 1106388..1106639 1 NC_002942.5 hypothetical protein 1106639 3077865 lpg1013 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095046.1 1106388 D 272624 CDS YP_095047.1 52841248 3077984 1106700..1106873 1 NC_002942.5 dehydrogenase 1106873 3077984 lpg1014 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dehydrogenase YP_095047.1 1106700 D 272624 CDS YP_095048.1 52841249 3080472 1106967..1107497 1 NC_002942.5 conserved gene, perhaps benzil (sepiapterin, ketoacyl) reductase; hypothetical protein 1107497 yueD 3080472 yueD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095048.1 1106967 D 272624 CDS YP_095049.1 52841250 3079892 complement(1107779..1108663) 1 NC_002942.5 hypothetical protein 1108663 3079892 lpg1016 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095049.1 1107779 R 272624 CDS YP_095050.1 52841251 3077895 1109618..1112146 1 NC_002942.5 cation efflux transporter 1112146 mgtA 3077895 mgtA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation efflux transporter YP_095050.1 1109618 D 272624 CDS YP_095051.1 52841252 3078920 1112133..1113392 1 NC_002942.5 chemiosmotic efflux system B protein C 1113392 3078920 lpg1018 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein C YP_095051.1 1112133 D 272624 CDS YP_095052.1 52841253 3078471 1113389..1114522 1 NC_002942.5 chemiosmotic efflux system B protein B 1114522 3078471 lpg1019 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein B YP_095052.1 1113389 D 272624 CDS YP_095053.1 52841254 3079624 1114601..1117744 1 NC_002942.5 chemiosmotic efflux system B protein A 1117744 3079624 lpg1020 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein A YP_095053.1 1114601 D 272624 CDS YP_095054.1 52841255 3079423 1117741..1119102 1 NC_002942.5 metallo-beta lactamase 1119102 3079423 lpg1021 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metallo-beta lactamase YP_095054.1 1117741 D 272624 CDS YP_095055.1 52841256 3078614 1119060..1120613 1 NC_002942.5 catalyzes the formation of thymine and 2-deoxy-alpha-D-ribose 1-phosphate from thymidine; thymidine phosphorylase 1120613 deoA 3078614 deoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thymidine phosphorylase YP_095055.1 1119060 D 272624 CDS YP_095056.1 52841257 3079711 1120610..1121521 1 NC_002942.5 Catalyzes the formation of PRPP from ATP and ribose 5-phosphate; phosphoribosylpyrophosphate synthetase 1121521 3079711 lpg1023 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylpyrophosphate synthetase YP_095056.1 1120610 D 272624 CDS YP_095057.1 52841258 3078094 1121779..1123989 1 NC_002942.5 copper efflux ATPase 1123989 3078094 lpg1024 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 copper efflux ATPase YP_095057.1 1121779 D 272624 CDS YP_095058.1 52841259 3079445 1124129..1125010 1 NC_002942.5 sensory box/GGDEF family protein 1125010 yegE 3079445 yegE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box/GGDEF family protein YP_095058.1 1124129 D 272624 CDS YP_095059.1 52841260 3077982 1125147..1125521 1 NC_002942.5 outer membrane lipoprotein 1125521 3077982 lpg1026 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane lipoprotein YP_095059.1 1125147 D 272624 CDS YP_095060.1 52841261 3078580 1125522..1126859 1 NC_002942.5 chemiosmotic efflux system C protein C 1126859 3078580 lpg1027 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system C protein C YP_095060.1 1125522 D 272624 CDS YP_095061.1 52841262 3078568 1126856..1127824 1 NC_002942.5 chemiosmotic efflux system C protein B 1127824 3078568 lpg1028 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system C protein B YP_095061.1 1126856 D 272624 CDS YP_095062.1 52841263 3080349 1127825..1131040 1 NC_002942.5 chemiosmotic efflux system protein A-like protein 1131040 3080349 lpg1029 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system protein A-like protein YP_095062.1 1127825 D 272624 CDS YP_095063.1 52841264 3078283 1131037..1131489 1 NC_002942.5 hypothetical protein 1131489 3078283 lpg1030 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095063.1 1131037 D 272624 CDS YP_095064.1 52841265 3077965 complement(1131628..1131972) 1 NC_002942.5 hypothetical protein 1131972 3077965 lpg1031 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095064.1 1131628 R 272624 CDS YP_095065.1 52841266 3080182 1132175..1133854 1 NC_002942.5 hypothetical protein 1133854 3080182 lpg1032 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095065.1 1132175 D 272624 CDS YP_095066.1 52841267 3078026 complement(1133866..1134072) 1 NC_002942.5 hypothetical protein 1134072 3078026 lpg1033 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095066.1 1133866 R 272624 CDS YP_095067.1 52841268 3079849 1134218..1134745 1 NC_002942.5 hypothetical protein 1134745 3079849 lpg1034 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095067.1 1134218 D 272624 CDS YP_095068.1 52841269 3078857 1134772..1137846 1 NC_002942.5 copper efflux ATPase 1137846 pcoA 3078857 pcoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 copper efflux ATPase YP_095068.1 1134772 D 272624 CDS YP_095069.1 52841270 3078178 complement(1138084..1138551) 1 NC_002942.5 outer membrane lipoprotein 1138551 3078178 lpg1036 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane lipoprotein YP_095069.1 1138084 R 272624 CDS YP_095070.1 52841271 3078422 complement(1138657..1138824) 1 NC_002942.5 hypothetical protein 1138824 3078422 lpg1037 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095070.1 1138657 R 272624 CDS YP_095071.1 52841272 3079917 complement(1139067..1139384) 1 NC_002942.5 VrrB 1139384 3079917 lpg1038 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 VrrB YP_095071.1 1139067 R 272624 CDS YP_095072.1 52841273 3078056 1139570..1139866 1 NC_002942.5 hypothetical protein 1139866 3078056 lpg1039 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095072.1 1139570 D 272624 CDS YP_095073.1 52841274 3079947 1139872..1140537 1 NC_002942.5 S-isoprenylcysteine methyltransferase 1140537 3079947 lpg1040 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 S-isoprenylcysteine methyltransferase YP_095073.1 1139872 D 272624 CDS YP_095074.1 52841275 3079581 1140537..1141034 1 NC_002942.5 hypothetical protein 1141034 3079581 lpg1041 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095074.1 1140537 D 272624 CDS YP_095075.1 52841276 3080065 complement(1141102..1142019) 1 NC_002942.5 hypothetical protein 1142019 3080065 lpg1042 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095075.1 1141102 R 272624 CDS YP_095076.1 52841277 3077800 complement(1141920..1142681) 1 NC_002942.5 hypothetical protein 1142681 3077800 lpg1043 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095076.1 1141920 R 272624 CDS YP_095077.1 52841278 3079467 complement(1142681..1144654) 1 NC_002942.5 oxidoreductase, FAD-binding 1144654 3079467 lpg1044 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase, FAD-binding YP_095077.1 1142681 R 272624 CDS YP_095078.1 52841279 3079403 1144669..1144863 1 NC_002942.5 hypothetical protein 1144863 3079403 lpg1045 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095078.1 1144669 D 272624 CDS YP_095079.1 52841280 3078977 1144897..1145286 1 NC_002942.5 hypothetical protein 1145286 3078977 lpg1046 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095079.1 1144897 D 272624 CDS YP_095080.1 52841281 3078044 complement(1145318..1146187) 1 NC_002942.5 ATP synthase subunit gamma C-terminus 1146187 atpG 3078044 atpG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase subunit gamma C-terminus YP_095080.1 1145318 R 272624 CDS YP_095081.1 52841282 3080316 complement(1146245..1147717) 1 NC_002942.5 produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1147717 3080316 lpg1048 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit alpha YP_095081.1 1146245 R 272624 CDS YP_095082.1 52841283 3077797 complement(1147704..1148447) 1 NC_002942.5 H(+) transporting ATP synthase subunit B 1148447 3077797 lpg1049 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 H(+) transporting ATP synthase subunit B YP_095082.1 1147704 R 272624 CDS YP_095083.1 52841284 3079166 complement(1148453..1148641) 1 NC_002942.5 ATP synthase subunit C 1148641 3079166 lpg1050 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase subunit C YP_095083.1 1148453 R 272624 CDS YP_095084.1 52841285 3078824 complement(1148725..1149417) 1 NC_002942.5 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1149417 atpA 3078824 atpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit A YP_095084.1 1148725 R 272624 CDS YP_095085.1 52841286 3078556 complement(1149420..1149698) 1 NC_002942.5 ATP synthase 1149698 3078556 lpg1052 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase YP_095085.1 1149420 R 272624 CDS YP_095086.1 52841287 3079013 complement(1149688..1150098) 1 NC_002942.5 ATP synthase F0F1 subunit epsilon 1150098 3079013 lpg1053 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit epsilon YP_095086.1 1149688 R 272624 CDS YP_095087.1 52841288 3080569 complement(1150107..1151531) 1 NC_002942.5 produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1151531 atpD 3080569 atpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit beta YP_095087.1 1150107 R 272624 CDS YP_095088.1 52841289 3080413 complement(1151869..1152309) 1 NC_002942.5 hypothetical protein 1152309 3080413 lpg1055 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095088.1 1151869 R 272624 CDS YP_095089.1 52841290 3080306 1154000..1154542 1 NC_002942.5 guanylate cyclase 1154542 3080306 lpg1056 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanylate cyclase YP_095089.1 1154000 D 272624 CDS YP_095090.1 52841291 3080321 1154508..1156028 1 NC_002942.5 sensory box/GGDEF family protein 1156028 3080321 lpg1057 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box/GGDEF family protein YP_095090.1 1154508 D 272624 CDS YP_095091.1 52841292 3078555 1156198..1158000 1 NC_002942.5 polyhydroxyalkanoic synthase 1158000 phbC 3078555 phbC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polyhydroxyalkanoic synthase YP_095091.1 1156198 D 272624 CDS YP_095092.1 52841293 3080419 complement(1158151..1158948) 1 NC_002942.5 acetoacetyl CoA reductase 1158948 phaB 3080419 phaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetoacetyl CoA reductase YP_095092.1 1158151 R 272624 CDS YP_095093.1 52841294 3079312 complement(1158966..1159229) 1 NC_002942.5 cold shock domain-contain protein 1159229 3079312 lpg1060 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock domain-contain protein YP_095093.1 1158966 R 272624 CDS YP_095094.1 52841295 3079682 complement(1159281..1159739) 1 NC_002942.5 hypothetical protein 1159739 3079682 lpg1061 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095094.1 1159281 R 272624 CDS YP_095095.1 52841296 3079068 1159897..1160925 1 NC_002942.5 hypothetical protein 1160925 3079068 lpg1062 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095095.1 1159897 D 272624 CDS YP_095096.1 52841297 3080200 complement(1161307..1162599) 1 NC_002942.5 proline/betaine transporter ProP6 1162599 proP6 3080200 proP6 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proline/betaine transporter ProP6 YP_095096.1 1161307 R 272624 CDS YP_095097.1 52841298 3080193 complement(1162604..1163122) 1 NC_002942.5 polypeptide deformylase 1163122 3080193 lpg1064 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polypeptide deformylase YP_095097.1 1162604 R 272624 CDS YP_095098.1 52841299 3078577 complement(1163106..1163744) 1 NC_002942.5 hypothetical protein 1163744 3078577 lpg1065 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095098.1 1163106 R 272624 CDS YP_095099.1 52841300 3080197 complement(1163707..1164264) 1 NC_002942.5 hypothetical protein 1164264 3080197 lpg1066 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095099.1 1163707 R 272624 CDS YP_095100.1 52841301 3079799 1164408..1164665 1 NC_002942.5 hypothetical protein 1164665 3079799 lpg1067 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095100.1 1164408 D 272624 CDS YP_095101.1 52841302 3079205 1164677..1164880 1 NC_002942.5 hypothetical protein 1164880 3079205 lpg1068 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095101.1 1164677 D 272624 CDS YP_095102.1 52841303 3079828 complement(1164904..1165926) 1 NC_002942.5 AbiD phage protein-like 1165926 3079828 lpg1069 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AbiD phage protein-like YP_095102.1 1164904 R 272624 CDS YP_095103.1 52841304 3080133 complement(1165936..1167117) 1 NC_002942.5 integrase, phage related 1167117 int 3080133 int Legionella pneumophila subsp. pneumophila str. Philadelphia 1 integrase, phage related YP_095103.1 1165936 R 272624 CDS YP_095104.1 52841305 3080623 complement(1167447..1167722) 1 NC_002942.5 transposase TnpA (Uma4) 1167722 3080623 lpg1071 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase TnpA (Uma4) YP_095104.1 1167447 R 272624 CDS YP_095105.1 52841306 3079063 complement(1167775..1168695) 1 NC_002942.5 transposase TnpA 1168695 3079063 lpg1072 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase TnpA YP_095105.1 1167775 R 272624 CDS YP_095106.1 52841307 3078332 1168784..1169911 1 NC_002942.5 hypothetical protein 1169911 3078332 lpg1073 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095106.1 1168784 D 272624 CDS YP_095107.1 52841308 3078892 complement(1170029..1171213) 1 NC_002942.5 hypothetical protein 1171213 3078892 lpg1074 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095107.1 1170029 R 272624 CDS YP_095108.1 52841309 3080464 1171464..1171805 1 NC_002942.5 hypothetical protein 1171805 3080464 lpg1075 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095108.1 1171464 D 272624 CDS YP_095109.1 52841310 3080179 complement(1171592..1171864) 1 NC_002942.5 hypothetical protein 1171864 3080179 lpg1076 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095109.1 1171592 R 272624 CDS YP_095110.1 52841311 3079410 complement(1172002..1173711) 1 NC_002942.5 hypothetical protein 1173711 3079410 lpg1077 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095110.1 1172002 R 272624 CDS YP_095111.1 52841312 3078604 complement(1173776..1174147) 1 NC_002942.5 hypothetical protein 1174147 3078604 lpg1078 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095111.1 1173776 R 272624 CDS YP_095112.1 52841313 3078269 1174402..1174572 1 NC_002942.5 hypothetical protein 1174572 3078269 lpg1079 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095112.1 1174402 D 272624 CDS YP_095113.1 52841314 3080205 complement(1174611..1175966) 1 NC_002942.5 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1175966 3080205 lpg1080 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_095113.1 1174611 R 272624 CDS YP_095114.1 52841315 3078496 complement(1176202..1177704) 1 NC_002942.5 reverse transcriptase 1177704 3078496 lpg1081 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 reverse transcriptase YP_095114.1 1176202 R 272624 CDS YP_095115.1 52841316 3080108 1177925..1178332 1 NC_002942.5 hypothetical protein 1178332 3080108 lpg1082 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095115.1 1177925 D 272624 CDS YP_095116.1 52841317 3079008 1178481..1179164 1 NC_002942.5 hypothetical protein 1179164 3079008 lpg1083 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095116.1 1178481 D 272624 CDS YP_095117.1 52841318 3080240 complement(1179250..1180281) 1 NC_002942.5 hypothetical protein 1180281 3080240 lpg1084 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095117.1 1179250 R 272624 CDS YP_095118.1 52841319 3080156 complement(1180278..1181522) 1 NC_002942.5 phage related integrase 1181522 3080156 lpg1085 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phage related integrase YP_095118.1 1180278 R 272624 CDS YP_095119.1 52841320 3080085 1181858..1183306 1 NC_002942.5 IS4 family transposase TnpA 1183306 3080085 lpg1086 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS4 family transposase TnpA YP_095119.1 1181858 D 272624 CDS YP_095120.1 52841321 3080340 1183472..1185079 1 NC_002942.5 virulence factor MviN 1185079 3080340 lpg1087 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 virulence factor MviN YP_095120.1 1183472 D 272624 CDS YP_095121.1 52841322 3078226 1185394..1187199 1 NC_002942.5 conserved gene, may be fused genes; nucleotidyltransferase 1187199 3078226 lpg1088 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleotidyltransferase YP_095121.1 1185394 D 272624 CDS YP_095122.1 52841323 3080556 1187306..1187917 1 NC_002942.5 methyltransferase 1187917 3080556 lpg1089 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methyltransferase YP_095122.1 1187306 D 272624 CDS YP_095123.1 52841324 3080178 1188292..1188813 1 NC_002942.5 hypothetical protein 1188813 3080178 lpg1090 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095123.1 1188292 D 272624 CDS YP_095124.1 52841325 3078576 1189117..1189560 1 NC_002942.5 hypothetical protein 1189560 3078576 lpg1091 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095124.1 1189117 D 272624 CDS YP_095125.1 52841326 3080172 1190100..1190813 1 NC_002942.5 beta-phosphoglucomutase 1190813 3080172 lpg1092 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 beta-phosphoglucomutase YP_095125.1 1190100 D 272624 CDS YP_095126.1 52841327 3079643 1191286..1194000 1 NC_002942.5 cation efflux transporter 1194000 pacL 3079643 pacL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation efflux transporter YP_095126.1 1191286 D 272624 CDS YP_095127.1 52841328 3080629 1193984..1195243 1 NC_002942.5 chemiosmotic efflux system B protein C 1195243 3080629 lpg1094 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein C YP_095127.1 1193984 D 272624 CDS YP_095128.1 52841329 3078186 1195240..1196376 1 NC_002942.5 chemiosmotic efflux system B protein B 1196376 3078186 lpg1095 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein B YP_095128.1 1195240 D 272624 CDS YP_095129.1 52841330 3079150 1196391..1199543 1 NC_002942.5 chemiosmotic efflux system B protein A 1199543 3079150 lpg1096 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system B protein A YP_095129.1 1196391 D 272624 CDS YP_095130.1 52841331 3078147 1199936..1201723 1 NC_002942.5 polyhydroxyalkanoic synthase 1201723 phbC 3078147 phbC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polyhydroxyalkanoic synthase YP_095130.1 1199936 D 272624 CDS YP_095131.1 52841332 3079969 1202264..1202455 1 NC_002942.5 hypothetical protein 1202455 3079969 lpg1098 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095131.1 1202264 D 272624 CDS YP_095132.1 52841333 3080463 1202600..1203058 1 NC_002942.5 hypothetical protein 1203058 3080463 lpg1099 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095132.1 1202600 D 272624 CDS YP_095133.1 52841334 3080352 1203181..1203783 1 NC_002942.5 proton transporter 1203783 3080352 lpg1100 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proton transporter YP_095133.1 1203181 D 272624 CDS YP_095134.1 52841335 3080083 1204272..1205240 1 NC_002942.5 hypothetical protein 1205240 3080083 lpg1101 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095134.1 1204272 D 272624 CDS YP_095135.1 52841336 3079390 complement(1205522..1206385) 1 NC_002942.5 hypothetical protein 1206385 3079390 lpg1102 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095135.1 1205522 R 272624 CDS YP_095136.1 52841337 3078302 1206678..1207889 1 NC_002942.5 hypothetical protein 1207889 3078302 lpg1103 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095136.1 1206678 D 272624 CDS YP_095137.1 52841338 3079773 complement(1207933..1208925) 1 NC_002942.5 hypothetical protein 1208925 3079773 lpg1104 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095137.1 1207933 R 272624 CDS YP_095138.1 52841339 3078007 1209124..1209627 1 NC_002942.5 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1209627 3078007 lpg1105 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionine sulfoxide reductase B YP_095138.1 1209124 D 272624 CDS YP_095139.1 52841340 3079259 complement(1209726..1211000) 1 NC_002942.5 hypothetical protein 1211000 3079259 lpg1106 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095139.1 1209726 R 272624 CDS YP_095140.1 52841341 3080444 complement(1211242..1211661) 1 NC_002942.5 transporter family protein 1211661 3080444 lpg1107 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter family protein YP_095140.1 1211242 R 272624 CDS YP_095141.1 52841342 3078087 complement(1211847..1212728) 1 NC_002942.5 lipase 1212728 3078087 lpg1108 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipase YP_095141.1 1211847 R 272624 CDS YP_095142.1 52841343 3079025 complement(1212967..1215027) 1 NC_002942.5 hypothetical protein 1215027 3079025 lpg1109 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095142.1 1212967 R 272624 CDS YP_095143.1 52841344 3078832 1215532..1216227 1 NC_002942.5 hypothetical protein 1216227 3078832 lpg1110 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095143.1 1215532 D 272624 CDS YP_095144.1 52841345 3078763 complement(1216316..1216954) 1 NC_002942.5 hypothetical protein 1216954 3078763 lpg1111 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095144.1 1216316 R 272624 CDS YP_095145.1 52841346 3078323 complement(1217235..1217618) 1 NC_002942.5 hypothetical protein 1217618 3078323 lpg1112 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095145.1 1217235 R 272624 CDS YP_095146.1 52841347 3079051 complement(1217834..1218574) 1 NC_002942.5 hypothetical protein 1218574 3079051 lpg1113 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095146.1 1217834 R 272624 CDS YP_095147.1 52841348 3078626 complement(1218657..1221026) 1 NC_002942.5 sensory box protein 1221026 3078626 lpg1114 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_095147.1 1218657 R 272624 CDS YP_095148.1 52841349 3080363 complement(1221312..1222988) 1 NC_002942.5 acts as a promotor non-specific transcription repressor; circadian clock protein KaiC 1222988 kaiC2 3080363 kaiC2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 circadian clock protein KaiC YP_095148.1 1221312 R 272624 CDS YP_095149.1 52841350 3080274 1223381..1225732 1 NC_002942.5 hypothetical protein 1225732 3080274 lpg1116 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095149.1 1223381 D 272624 CDS YP_095150.1 52841351 3079593 complement(1225771..1226244) 1 NC_002942.5 hypothetical protein 1226244 paiA 3079593 paiA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095150.1 1225771 R 272624 CDS YP_095151.1 52841352 3079512 complement(1226336..1227451) 1 NC_002942.5 serine-type D-Ala-D-Ala carboxypeptidase 1227451 3079512 lpg1118 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine-type D-Ala-D-Ala carboxypeptidase YP_095151.1 1226336 R 272624 CDS YP_095152.1 52841353 3079913 1227719..1228783 1 NC_002942.5 conserved gene, eukaryotic gene Map, similar to Drosophila acid phosphatase-1; major acid phosphatase 1228783 3079913 lpg1119 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major acid phosphatase YP_095152.1 1227719 D 272624 CDS YP_095153.1 52841354 3078345 complement(1229115..1230881) 1 NC_002942.5 hypothetical protein 1230881 3078345 lpg1120 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095153.1 1229115 R 272624 CDS YP_095154.1 52841355 3079782 1231463..1232233 1 NC_002942.5 hypothetical protein 1232233 3079782 lpg1121 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095154.1 1231463 D 272624 CDS YP_095155.1 52841356 3080032 1232861..1234189 1 NC_002942.5 membrane bound lytic murein transglycosylase D 1234189 3080032 lpg1122 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane bound lytic murein transglycosylase D YP_095155.1 1232861 D 272624 CDS YP_095156.1 52841357 3080020 complement(1234315..1235076) 1 NC_002942.5 arginine ABC transporter substrate-binding protein 1235076 artJ 3080020 artJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine ABC transporter substrate-binding protein YP_095156.1 1234315 R 272624 CDS YP_095157.1 52841358 3080079 complement(1235312..1235902) 1 NC_002942.5 hypothetical protein 1235902 3080079 lpg1124 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095157.1 1235312 R 272624 CDS YP_095158.1 52841359 3080001 1236120..1236878 1 NC_002942.5 amino acid ABC transporter substrate-binding protein 1236878 3080001 lpg1125 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid ABC transporter substrate-binding protein YP_095158.1 1236120 D 272624 CDS YP_095159.1 52841360 3080537 1237161..1240622 1 NC_002942.5 calcium-transporting ATPase 1240622 3080537 lpg1126 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 calcium-transporting ATPase YP_095159.1 1237161 D 272624 CDS YP_095160.1 52841361 3079950 complement(1240718..1242226) 1 NC_002942.5 acyl CoA synthetase, long chain fatty acid:CoA ligase 1242226 3079950 lpg1127 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA synthetase, long chain fatty acid:CoA ligase YP_095160.1 1240718 R 272624 CDS YP_095161.1 52841362 3078913 1242309..1242773 1 NC_002942.5 cytidine/deoxycytidylate deaminase 1242773 3078913 lpg1128 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytidine/deoxycytidylate deaminase YP_095161.1 1242309 D 272624 CDS YP_095162.1 52841363 3078369 1243201..1244760 1 NC_002942.5 hypothetical protein 1244760 3078369 lpg1129 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095162.1 1243201 D 272624 CDS YP_095163.1 52841364 3078492 complement(1244889..1246340) 1 NC_002942.5 adenylate cyclase 1246340 cyaA4 3078492 cyaA4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylate cyclase YP_095163.1 1244889 R 272624 CDS YP_095164.1 52841365 3079091 complement(1246993..1248159) 1 NC_002942.5 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1248159 cfa 3079091 cfa Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cyclopropane-fatty-acyl-phospholipid synthase YP_095164.1 1246993 R 272624 CDS YP_095165.1 52841366 3080631 complement(1248174..1248554) 1 NC_002942.5 hypothetical protein 1248554 3080631 lpg1132 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095165.1 1248174 R 272624 CDS YP_095166.1 52841367 3078945 1248525..1248704 1 NC_002942.5 hypothetical protein 1248704 3078945 lpg1133 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095166.1 1248525 D 272624 CDS YP_095167.1 52841368 3078204 complement(1248771..1249823) 1 NC_002942.5 nitropropane dioxygenase/trans-enoyl-CoA reductase 1249823 3078204 lpg1134 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitropropane dioxygenase/trans-enoyl-CoA reductase YP_095167.1 1248771 R 272624 CDS YP_095168.1 52841369 3079149 complement(1249801..1250412) 1 NC_002942.5 TetR family regulatory protein 1250412 3079149 lpg1135 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TetR family regulatory protein YP_095168.1 1249801 R 272624 CDS YP_095169.1 52841370 3078310 1250582..1251484 1 NC_002942.5 hypothetical protein 1251484 3078310 lpg1136 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095169.1 1250582 D 272624 CDS YP_095170.1 52841371 3080403 complement(1252018..1252986) 1 NC_002942.5 hypothetical protein 1252986 3080403 lpg1137 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095170.1 1252018 R 272624 CDS YP_095171.1 52841372 3080552 complement(1253246..1254268) 1 NC_002942.5 spermidine/putrescine ABC transporter substrate-binding protein 1254268 3080552 lpg1138 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spermidine/putrescine ABC transporter substrate-binding protein YP_095171.1 1253246 R 272624 CDS YP_095172.1 52841373 3080586 complement(1254265..1255032) 1 NC_002942.5 spermidine/putrescine ABC transporter permease 1255032 potC 3080586 potC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spermidine/putrescine ABC transporter permease YP_095172.1 1254265 R 272624 CDS YP_095173.1 52841374 3080468 complement(1255029..1255853) 1 NC_002942.5 spermidine/putrescine ABC transporter permease PotB 1255853 potB 3080468 potB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spermidine/putrescine ABC transporter permease PotB YP_095173.1 1255029 R 272624 CDS YP_095174.1 52841375 3080476 complement(1255843..1256991) 1 NC_002942.5 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1256991 potA 3080476 potA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 putrescine/spermidine ABC transporter ATPase YP_095174.1 1255843 R 272624 CDS YP_095175.1 52841376 3080461 complement(1257167..1257397) 1 NC_002942.5 hypothetical protein 1257397 3080461 lpg1142 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095175.1 1257167 R 272624 CDS YP_095176.1 52841377 3080372 complement(1257597..1258481) 1 NC_002942.5 short chain type dehydrogenase/reductase 1258481 3080372 lpg1143 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain type dehydrogenase/reductase YP_095176.1 1257597 R 272624 CDS YP_095177.1 52841378 3080235 complement(1258828..1259334) 1 NC_002942.5 hypothetical protein 1259334 3080235 lpg1144 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095177.1 1258828 R 272624 CDS YP_095178.1 52841379 3080465 1259593..1261902 1 NC_002942.5 hypothetical protein 1261902 3080465 lpg1145 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095178.1 1259593 D 272624 CDS YP_095179.1 52841380 3080564 1262032..1263513 1 NC_002942.5 thermostable carboxypeptidase 1 1263513 3080564 lpg1146 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thermostable carboxypeptidase 1 YP_095179.1 1262032 D 272624 CDS YP_095180.1 52841381 3080437 1263574..1264077 1 NC_002942.5 hypothetical protein 1264077 3080437 lpg1147 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095180.1 1263574 D 272624 CDS YP_095181.1 52841382 3080404 1264367..1265878 1 NC_002942.5 hypothetical protein 1265878 3080404 lpg1148 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095181.1 1264367 D 272624 CDS YP_095182.1 52841383 3080266 1266056..1266838 1 NC_002942.5 hypothetical protein 1266838 3080266 lpg1149 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095182.1 1266056 D 272624 CDS YP_095183.1 52841384 3080351 1266926..1268005 1 NC_002942.5 transcription regulator protein 1268005 3080351 lpg1150 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription regulator protein YP_095183.1 1266926 D 272624 CDS YP_095184.1 52841385 3080401 complement(1268082..1269605) 1 NC_002942.5 hypothetical protein 1269605 3080401 lpg1151 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095184.1 1268082 R 272624 CDS YP_095185.1 52841386 3080350 complement(1269764..1270720) 1 NC_002942.5 hypothetical protein 1270720 3080350 lpg1152 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095185.1 1269764 R 272624 CDS YP_095186.1 52841387 3080365 complement(1270620..1272107) 1 NC_002942.5 amine oxidase 1272107 3080365 lpg1153 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amine oxidase YP_095186.1 1270620 R 272624 CDS YP_095187.1 52841388 3080332 1272593..1273675 1 NC_002942.5 hypothetical protein 1273675 3080332 lpg1154 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095187.1 1272593 D 272624 CDS YP_095188.1 52841389 3080616 1273915..1275594 1 NC_002942.5 pyruvate decarboxylase 1275594 3080616 lpg1155 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate decarboxylase YP_095188.1 1273915 D 272624 CDS YP_095189.1 52841390 3080360 complement(1275652..1276848) 1 NC_002942.5 aminopeptidase 1276848 3080360 lpg1156 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminopeptidase YP_095189.1 1275652 R 272624 CDS YP_095190.1 52841391 3080426 1277254..1278018 1 NC_002942.5 lipase B 1278018 3080426 lpg1157 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipase B YP_095190.1 1277254 D 272624 CDS YP_095191.1 52841392 3080540 1278130..1278900 1 NC_002942.5 hypothetical protein 1278900 3080540 lpg1158 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095191.1 1278130 D 272624 CDS YP_095192.1 52841393 3080528 1279271..1280308 1 NC_002942.5 permeases of drug/transporter 1280308 3080528 lpg1159 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 permeases of drug/transporter YP_095192.1 1279271 D 272624 CDS YP_095193.1 52841394 3077709 complement(1280410..1280655) 1 NC_002942.5 hypothetical protein 1280655 3077709 lpg1160 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095193.1 1280410 R 272624 CDS YP_095194.1 52841395 3080271 1280973..1281635 1 NC_002942.5 phosphoribosyltransferase 1281635 3080271 lpg1161 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosyltransferase YP_095194.1 1280973 D 272624 CDS YP_095195.1 52841396 3078411 complement(1281791..1282522) 1 NC_002942.5 OmpA-like transmembrane domain-containing protein 1282522 3078411 lpg1162 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 OmpA-like transmembrane domain-containing protein YP_095195.1 1281791 R 272624 CDS YP_095196.1 52841397 3078634 1282693..1283979 1 NC_002942.5 MFS transporter 1283979 3078634 lpg1163 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MFS transporter YP_095196.1 1282693 D 272624 CDS YP_095197.1 52841398 3078167 1283991..1285145 1 NC_002942.5 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; acetylornithine deacetylase 1285145 argE 3078167 argE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetylornithine deacetylase YP_095197.1 1283991 D 272624 CDS YP_095198.1 52841399 3078243 1285388..1286185 1 NC_002942.5 uridine kinase 1286185 udk 3078243 udk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uridine kinase YP_095198.1 1285388 D 272624 CDS YP_095199.1 52841400 3079052 complement(1286250..1288262) 1 NC_002942.5 hypothetical protein 1288262 3079052 lpg1166 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095199.1 1286250 R 272624 CDS YP_095200.2 161723256 3080579 1288522..1289007 1 NC_002942.5 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1289007 3080579 lpg1167 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleotide-binding protein YP_095200.2 1288522 D 272624 CDS YP_095201.1 52841402 3079702 complement(1289130..1291397) 1 NC_002942.5 sensory box protein 1291397 3079702 lpg1168 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_095201.1 1289130 R 272624 CDS YP_095202.1 52841403 3080242 complement(1291551..1292912) 1 NC_002942.5 hypothetical protein 1292912 3080242 lpg1169 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095202.1 1291551 R 272624 CDS YP_095203.1 52841404 3080250 1292948..1294042 1 NC_002942.5 pyruvate formate lyase-activating enzyme PflA 1294042 3080250 lpg1170 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate formate lyase-activating enzyme PflA YP_095203.1 1292948 D 272624 CDS YP_095204.1 52841405 3080236 1294101..1294520 1 NC_002942.5 hypothetical protein 1294520 3080236 lpg1171 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095204.1 1294101 D 272624 CDS YP_095205.1 52841406 3080246 1294669..1296156 1 NC_002942.5 hypothetical protein 1296156 3080246 lpg1172 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095205.1 1294669 D 272624 CDS YP_095206.1 52841407 3080203 1296252..1297838 1 NC_002942.5 sensor protein PilS 1297838 pilS 3080203 pilS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor protein PilS YP_095206.1 1296252 D 272624 CDS YP_095207.1 52841408 3080237 1297835..1299163 1 NC_002942.5 two component response regulator PilR 1299163 pilR 3080237 pilR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component response regulator PilR YP_095207.1 1297835 D 272624 CDS YP_095208.1 52841409 3080239 complement(1300274..1301209) 1 NC_002942.5 alpha/beta hydrolase 1301209 3080239 lpg1175 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha/beta hydrolase YP_095208.1 1300274 R 272624 CDS YP_095209.1 52841410 3080270 complement(1301488..1302936) 1 NC_002942.5 Zn-dependent protease 1302936 3080270 lpg1176 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Zn-dependent protease YP_095209.1 1301488 R 272624 CDS YP_095210.1 52841411 3080253 1302987..1304060 1 NC_002942.5 riboflavin biosynthesis protein RibD 1304060 ribD 3080253 ribD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 riboflavin biosynthesis protein RibD YP_095210.1 1302987 D 272624 CDS YP_095211.1 52841412 3080234 1304045..1304659 1 NC_002942.5 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1304659 ribE 3080234 ribE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 riboflavin synthase subunit alpha YP_095211.1 1304045 D 272624 CDS YP_095212.1 52841413 3078420 1304656..1305864 1 NC_002942.5 riboflavin biosynthesis protein RibA 1305864 ribA 3078420 ribA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 riboflavin biosynthesis protein RibA YP_095212.1 1304656 D 272624 CDS YP_095213.1 52841414 3078891 1305872..1306339 1 NC_002942.5 riboflavin synthase subunit beta 1306339 ribH 3078891 ribH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 riboflavin synthase subunit beta YP_095213.1 1305872 D 272624 CDS YP_095214.1 52841415 3078755 1306465..1308102 1 NC_002942.5 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1308102 pyrG 3078755 pyrG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CTP synthetase YP_095214.1 1306465 D 272624 CDS YP_095215.1 52841416 3078207 1308099..1308923 1 NC_002942.5 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1308923 kdsA 3078207 kdsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-dehydro-3-deoxyphosphooctonate aldolase YP_095215.1 1308099 D 272624 CDS YP_095216.1 52841417 3078695 1309096..1310988 1 NC_002942.5 hypothetical protein 1310988 3078695 lpg1183 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095216.1 1309096 D 272624 CDS YP_095217.1 52841418 3078709 1311080..1313467 1 NC_002942.5 outer membrane protein RomA 1313467 3078709 lpg1184 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane protein RomA YP_095217.1 1311080 D 272624 CDS YP_095218.1 52841419 3077821 1313842..1314624 1 NC_002942.5 competence lipoprotein ComL 1314624 3077821 lpg1186 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 competence lipoprotein ComL YP_095218.1 1313842 D 272624 CDS YP_095219.1 52841420 3077810 complement(1314772..1315716) 1 NC_002942.5 Required for efficient pilin antigenic variation; recombination associated protein 1315716 rdgC 3077810 rdgC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 recombination associated protein YP_095219.1 1314772 R 272624 CDS YP_095220.1 52841421 3080217 complement(1315828..1317723) 1 NC_002942.5 Kup system potassium uptake protein 1317723 kup2 3080217 kup2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Kup system potassium uptake protein YP_095220.1 1315828 R 272624 CDS YP_095221.1 52841422 3077718 complement(1317730..1318731) 1 NC_002942.5 hypothetical protein 1318731 3077718 lpg1189 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095221.1 1317730 R 272624 CDS YP_095222.1 52841423 3077696 1318791..1319963 1 NC_002942.5 hypothetical protein 1319963 3077696 lpg1190 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095222.1 1318791 D 272624 CDS YP_095223.1 52841424 3080292 1320049..1321236 1 NC_002942.5 glycosyl hydrolase 1321236 3080292 lpg1191 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyl hydrolase YP_095223.1 1320049 D 272624 CDS YP_095224.1 52841425 3077658 1321346..1322101 1 NC_002942.5 ThiJ/PfpI family protein 1322101 3077658 lpg1192 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ThiJ/PfpI family protein YP_095224.1 1321346 D 272624 CDS YP_095225.1 52841426 3078151 complement(1322190..1322813) 1 NC_002942.5 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1322813 hisI 3078151 hisI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_095225.1 1322190 R 272624 CDS YP_095226.1 52841427 3080392 complement(1322810..1323577) 1 NC_002942.5 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1323577 3080392 lpg1194 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazole glycerol phosphate synthase subunit HisF YP_095226.1 1322810 R 272624 CDS YP_095227.1 52841428 3077897 complement(1323571..1324290) 1 NC_002942.5 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 1324290 hisA 3077897 hisA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_095227.1 1323571 R 272624 CDS YP_095228.1 52841429 3077775 complement(1324284..1324883) 1 NC_002942.5 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1324883 hisH 3077775 hisH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazole glycerol phosphate synthase subunit HisH YP_095228.1 1324284 R 272624 CDS YP_095229.1 52841430 3079235 complement(1324880..1325938) 1 NC_002942.5 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1325938 3079235 lpg1197 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_095229.1 1324880 R 272624 CDS YP_095230.1 52841431 3079005 complement(1325916..1327010) 1 NC_002942.5 histidinol-phosphate aminotransferase 1327010 hisC 3079005 hisC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 histidinol-phosphate aminotransferase YP_095230.1 1325916 R 272624 CDS YP_095231.1 52841432 3080215 complement(1327011..1328306) 1 NC_002942.5 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1328306 hisD 3080215 hisD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 histidinol dehydrogenase YP_095231.1 1327011 R 272624 CDS YP_095232.1 52841433 3077849 complement(1328312..1329250) 1 NC_002942.5 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1329250 hisG 3077849 hisG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP phosphoribosyltransferase YP_095232.1 1328312 R 272624 CDS YP_095233.1 52841434 3078523 1329862..1331394 1 NC_002942.5 cytochrome D ubiquinol oxidase, subunit I 1331394 cydA-2 3078523 cydA-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome D ubiquinol oxidase, subunit I YP_095233.1 1329862 D 272624 CDS YP_095234.1 52841435 3078028 1331410..1332546 1 NC_002942.5 cytochrome D ubiquinol oxidase subunit II 1332546 cydB 3078028 cydB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome D ubiquinol oxidase subunit II YP_095234.1 1331410 D 272624 CDS YP_095235.1 52841436 3080175 complement(1332772..1333404) 1 NC_002942.5 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1333404 pyrE 3080175 pyrE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 orotate phosphoribosyltransferase YP_095235.1 1332772 R 272624 CDS YP_095236.1 52841437 3079066 1333647..1333886 1 NC_002942.5 cold shock domain-contain protein CspA 1333886 3079066 lpg1205 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock domain-contain protein CspA YP_095236.1 1333647 D 272624 CDS YP_095237.1 52841438 3080281 1334396..1334968 1 NC_002942.5 sigma 54 modulation protein YhbH 1334968 3080281 lpg1206 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sigma 54 modulation protein YhbH YP_095237.1 1334396 D 272624 CDS YP_095238.1 52841439 3079727 1335128..1335583 1 NC_002942.5 hypothetical protein 1335583 3079727 lpg1207 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095238.1 1335128 D 272624 CDS YP_095239.1 52841440 3079743 complement(1335613..1336032) 1 NC_002942.5 MarR family transcriptional regulator 1336032 3079743 lpg1208 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MarR family transcriptional regulator YP_095239.1 1335613 R 272624 CDS YP_095240.1 52841441 3079435 1336110..1336898 1 NC_002942.5 hypothetical protein 1336898 3079435 lpg1209 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095240.1 1336110 D 272624 CDS YP_095241.1 52841442 3078524 1336859..1337443 1 NC_002942.5 acetyltransferase 1337443 3078524 lpg1210 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_095241.1 1336859 D 272624 CDS YP_095242.1 52841443 3078023 complement(1337473..1338144) 1 NC_002942.5 amino acid transporter LysE 1338144 3078023 lpg1211 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid transporter LysE YP_095242.1 1337473 R 272624 CDS YP_095243.1 52841444 3077793 1338388..1339359 1 NC_002942.5 conserved gene, may be fused protein; IAA acetyltransferase/MarR transcriptional regulatory protein 1339359 3077793 lpg1212 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IAA acetyltransferase/MarR transcriptional regulatory protein YP_095243.1 1338388 D 272624 CDS YP_095244.1 52841445 3078267 1339417..1339980 1 NC_002942.5 hypothetical protein 1339980 3078267 lpg1213 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095244.1 1339417 D 272624 CDS YP_095245.1 52841446 3080134 1340222..1341529 1 NC_002942.5 conserved gene, permeases of major facilitator superfamily-like; 2-acylglycerophosphoethanolamine acyltransferase 1341529 3080134 lpg1214 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-acylglycerophosphoethanolamine acyltransferase YP_095245.1 1340222 D 272624 CDS YP_095246.1 52841447 3080091 complement(1341674..1342624) 1 NC_002942.5 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1342624 hemF 3080091 hemF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coproporphyrinogen III oxidase YP_095246.1 1341674 R 272624 CDS YP_095247.1 52841448 3078978 1342824..1343216 1 NC_002942.5 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgB 1343216 flgB 3078978 flgB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal-body rod protein FlgB YP_095247.1 1342824 D 272624 CDS YP_095248.1 52841449 3079935 1343219..1343641 1 NC_002942.5 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1343641 flgC 3079935 flgC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body rod protein FlgC YP_095248.1 1343219 D 272624 CDS YP_095249.1 52841450 3079939 1343653..1344330 1 NC_002942.5 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1344330 flgD 3079939 flgD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body rod modification protein YP_095249.1 1343653 D 272624 CDS YP_095250.1 52841451 3079466 1344444..1345757 1 NC_002942.5 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1345757 flgE 3079466 flgE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook protein FlgE YP_095250.1 1344444 D 272624 CDS YP_095251.1 52841452 3080407 1345768..1346514 1 NC_002942.5 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1346514 flgF 3080407 flgF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body rod protein FlgF YP_095251.1 1345768 D 272624 CDS YP_095252.1 52841453 3078488 1346661..1347446 1 NC_002942.5 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1347446 flgG 3078488 flgG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body rod protein FlgG YP_095252.1 1346661 D 272624 CDS YP_095253.1 52841454 3080508 1347459..1348151 1 NC_002942.5 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar basal body L-ring protein 1348151 flgH 3080508 flgH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body L-ring protein YP_095253.1 1347459 D 272624 CDS YP_095254.1 52841455 3077936 1348109..1349293 1 NC_002942.5 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1349293 flgI 3077936 flgI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar basal body P-ring biosynthesis protein FlgA YP_095254.1 1348109 D 272624 CDS YP_095255.1 52841456 3080252 1349296..1350180 1 NC_002942.5 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1350180 flgJ 3080252 flgJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar rod assembly protein/muramidase FlgJ YP_095255.1 1349296 D 272624 CDS YP_095256.1 52841457 3079600 1350230..1352179 1 NC_002942.5 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1352179 flgK 3079600 flgK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook-associated protein FlgK YP_095256.1 1350230 D 272624 CDS YP_095257.1 52841458 3079931 1352183..1353418 1 NC_002942.5 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes.; flagellar hook-associated protein FlgL 1353418 flgL 3079931 flgL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook-associated protein FlgL YP_095257.1 1352183 D 272624 CDS YP_095258.1 52841459 3079299 1353613..1355409 1 NC_002942.5 hypothetical protein 1355409 3079299 lpg1227 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095258.1 1353613 D 272624 CDS YP_095259.1 52841460 3079307 1355802..1356863 1 NC_002942.5 hypothetical protein 1356863 3079307 lpg1228 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095259.1 1355802 D 272624 CDS YP_095260.1 52841461 3080506 1356847..1358064 1 NC_002942.5 site specific recombinase 1358064 3080506 lpg1229 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 site specific recombinase YP_095260.1 1356847 D 272624 CDS YP_095261.1 52841462 3077878 1358462..1359130 1 NC_002942.5 hypothetical protein 1359130 3077878 lpg1230 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095261.1 1358462 D 272624 CDS YP_095262.1 52841463 3079122 1359266..1359772 1 NC_002942.5 SOS response transcriptional regulator 1359772 umuD 3079122 umuD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SOS response transcriptional regulator YP_095262.1 1359266 D 272624 CDS YP_095263.1 52841464 3079687 1359759..1361036 1 NC_002942.5 UmuC 1361036 umuC 3079687 umuC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UmuC YP_095263.1 1359759 D 272624 CDS YP_095264.1 52841465 3080008 complement(1361650..1362450) 1 NC_002942.5 hypothetical protein 1362450 3080008 lpg1233 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095264.1 1361650 R 272624 CDS YP_095265.1 52841466 3078957 complement(1362988..1364187) 1 NC_002942.5 hypothetical protein 1364187 3078957 lpg1234 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095265.1 1362988 R 272624 CDS YP_095266.1 52841467 3080011 complement(1364344..1364772) 1 NC_002942.5 patch repair protein 1364772 vsr 3080011 vsr Legionella pneumophila subsp. pneumophila str. Philadelphia 1 patch repair protein YP_095266.1 1364344 R 272624 CDS YP_095267.1 52841468 3079825 1364928..1366178 1 NC_002942.5 modification methylase (Eco47II, Sau96I) 1366178 3079825 lpg1236 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 modification methylase (Eco47II, Sau96I) YP_095267.1 1364928 D 272624 CDS YP_095268.1 52841469 3079630 complement(1366153..1366905) 1 NC_002942.5 type II restriction enzyme (Eco47II, Sau96I) 1366905 3079630 lpg1237 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II restriction enzyme (Eco47II, Sau96I) YP_095268.1 1366153 R 272624 CDS YP_095269.1 52841470 3078441 complement(1367039..1368013) 1 NC_002942.5 hypothetical protein 1368013 3078441 lpg1238 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095269.1 1367039 R 272624 CDS YP_095270.1 52841471 3077706 complement(1368030..1368293) 1 NC_002942.5 hypothetical protein 1368293 3077706 lpg1239 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095270.1 1368030 R 272624 CDS YP_095271.1 52841472 3080086 complement(1368280..1368645) 1 NC_002942.5 hypothetical protein 1368645 3080086 lpg1240 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095271.1 1368280 R 272624 CDS YP_095272.1 52841473 3077690 1368713..1371382 1 NC_002942.5 conjugal transfer protein TraA 1371382 traA 3077690 traA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugal transfer protein TraA YP_095272.1 1368713 D 272624 CDS YP_095273.1 52841474 3077700 1371547..1372626 1 NC_002942.5 transposase, ISSod13 1372626 3077700 lpg1242 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase, ISSod13 YP_095273.1 1371547 D 272624 CDS YP_095274.1 52841475 3077699 complement(1372685..1373398) 1 NC_002942.5 hypothetical protein 1373398 3077699 lpg1243 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095274.1 1372685 R 272624 CDS YP_095275.1 52841476 3077701 complement(1373487..1374296) 1 NC_002942.5 protein LvrE 1374296 lvrE 3077701 lvrE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrE YP_095275.1 1373487 R 272624 CDS YP_095276.1 52841477 3077705 complement(1374382..1376457) 1 NC_002942.5 protein LvhD4 1376457 virD4 3077705 virD4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhD4 YP_095276.1 1374382 R 272624 CDS YP_095277.1 52841478 3077723 complement(1376276..1377313) 1 NC_002942.5 protein LvhB11 1377313 virB11 3077723 virB11 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB11 YP_095277.1 1376276 R 272624 CDS YP_095278.1 52841479 3077710 complement(1377282..1378373) 1 NC_002942.5 protein LvhB10 1378373 3077710 lpg1247 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB10 YP_095278.1 1377282 R 272624 CDS YP_095279.1 52841480 3077805 complement(1378370..1379122) 1 NC_002942.5 protein LvhB9 1379122 virB9 3077805 virB9 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB9 YP_095279.1 1378370 R 272624 CDS YP_095280.1 52841481 3077711 complement(1379119..1379835) 1 NC_002942.5 protein LvhB8 1379835 virB8 3077711 virB8 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB8 YP_095280.1 1379119 R 272624 CDS YP_095281.1 52841482 3077716 complement(1379832..1380872) 1 NC_002942.5 protein LvhB6 1380872 virB6 3077716 virB6 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB6 YP_095281.1 1379832 R 272624 CDS YP_095282.1 52841483 3077715 complement(1380876..1381271) 1 NC_002942.5 protein LvrD 1381271 lvrD 3077715 lvrD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrD YP_095282.1 1380876 R 272624 CDS YP_095283.1 52841484 3077719 complement(1381268..1381414) 1 NC_002942.5 protein LvhB7 1381414 3077719 lpg1252 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB7 YP_095283.1 1381268 R 272624 CDS YP_095284.1 52841485 3077726 complement(1381429..1382139) 1 NC_002942.5 protein LvhB5 1382139 virB5 3077726 virB5 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB5 YP_095284.1 1381429 R 272624 CDS YP_095285.1 52841486 3077721 complement(1382136..1384616) 1 NC_002942.5 protein LvhB4 1384616 virB4 3077721 virB4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB4 YP_095285.1 1382136 R 272624 CDS YP_095286.1 52841487 3077729 complement(1384603..1384833) 1 NC_002942.5 protein LvhB3 1384833 3077729 lpg1255 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvhB3 YP_095286.1 1384603 R 272624 CDS YP_095287.1 52841488 3077733 1384984..1385094 1 NC_002942.5 hypothetical protein 1385094 3077733 lpg1256 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095287.1 1384984 D 272624 CDS YP_095288.1 52841489 3077731 complement(1385181..1385384) 1 NC_002942.5 conserved gene, carbon storage regulator CsrA-like; protein LvrC 1385384 lvrC 3077731 lvrC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrC YP_095288.1 1385181 R 272624 CDS YP_095289.1 52841490 3077734 complement(1385397..1385870) 1 NC_002942.5 protein LvrB 1385870 lvrB 3077734 lvrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrB YP_095289.1 1385397 R 272624 CDS YP_095290.1 52841491 3077737 complement(1385725..1386591) 1 NC_002942.5 protein LvrA 1386591 lvrA 3077737 lvrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrA YP_095290.1 1385725 R 272624 CDS YP_095291.1 52841492 3077738 1386688..1387428 1 NC_002942.5 phage repressor 1387428 prpA 3077738 prpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phage repressor YP_095291.1 1386688 D 272624 CDS YP_095292.1 52841493 3077739 complement(1387521..1387910) 1 NC_002942.5 hypothetical protein 1387910 3077739 lpg1261 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095292.1 1387521 R 272624 CDS YP_095293.1 52841494 3077741 1388172..1388510 1 NC_002942.5 hypothetical protein 1388510 3077741 lpg1262 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095293.1 1388172 D 272624 CDS YP_095294.1 52841495 3077742 1388724..1389992 1 NC_002942.5 hypothetical protein 1389992 3077742 lpg1263 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095294.1 1388724 D 272624 CDS YP_095295.1 52841496 3077744 complement(1390448..1391935) 1 NC_002942.5 proton/peptide symporter family protein 1391935 3077744 lpg1264 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proton/peptide symporter family protein YP_095295.1 1390448 R 272624 CDS YP_095296.1 52841497 3077745 1392035..1393354 1 NC_002942.5 hypothetical protein 1393354 3077745 lpg1265 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095296.1 1392035 D 272624 CDS YP_095297.1 52841498 3077753 complement(1393322..1394122) 1 NC_002942.5 methylase 1394122 3077753 lpg1266 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methylase YP_095297.1 1393322 R 272624 CDS YP_095298.1 52841499 3077752 1394907..1395554 1 NC_002942.5 hypothetical protein 1395554 3077752 lpg1267 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095298.1 1394907 D 272624 CDS YP_095299.1 52841500 3077825 complement(1395801..1396625) 1 NC_002942.5 hypothetical protein 1396625 3077825 lpg1268 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095299.1 1395801 R 272624 CDS YP_095300.1 52841501 3077754 complement(1397311..1399347) 1 NC_002942.5 hypothetical protein 1399347 3077754 lpg1269 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095300.1 1397311 R 272624 CDS YP_095301.1 52841502 3077759 complement(1399280..1399738) 1 NC_002942.5 hypothetical protein 1399738 3077759 lpg1270 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095301.1 1399280 R 272624 CDS YP_095302.1 52841503 3077766 complement(1400011..1400796) 1 NC_002942.5 ISSod6 transposase, IS1301 1400796 3077766 lpg1271 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISSod6 transposase, IS1301 YP_095302.1 1400011 R 272624 CDS YP_095303.1 52841504 3077767 1401419..1402483 1 NC_002942.5 hypothetical protein 1402483 3077767 lpg1273 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095303.1 1401419 D 272624 CDS YP_095304.1 52841505 3077768 1402531..1402986 1 NC_002942.5 hypothetical protein 1402986 3077768 lpg1274 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095304.1 1402531 D 272624 CDS YP_095305.1 52841506 3077770 complement(1403064..1403348) 1 NC_002942.5 TrkA family protein 1403348 3077770 lpg1275 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TrkA family protein YP_095305.1 1403064 R 272624 CDS YP_095306.1 52841507 3077777 complement(1403689..1405320) 1 NC_002942.5 electron transferring flavoprotein dehydrogenase 1405320 3077777 lpg1276 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 electron transferring flavoprotein dehydrogenase YP_095306.1 1403689 R 272624 CDS YP_095307.1 52841508 3077774 1405541..1407367 1 NC_002942.5 ABC transporter ATP-binding protein 1407367 abcT3 3077774 abcT3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_095307.1 1405541 D 272624 CDS YP_095308.1 52841509 3077788 1407450..1407767 1 NC_002942.5 hypothetical protein 1407767 3077788 lpg1278 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095308.1 1407450 D 272624 CDS YP_095309.1 52841510 3077779 1407804..1408175 1 NC_002942.5 hypothetical protein 1408175 3077779 lpg1279 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095309.1 1407804 D 272624 CDS YP_095310.1 52841511 3077789 complement(1408223..1409947) 1 NC_002942.5 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1409947 sfcA 3077789 sfcA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malate dehydrogenase YP_095310.1 1408223 R 272624 CDS YP_095311.1 52841512 3077790 1410027..1410410 1 NC_002942.5 hypothetical protein 1410410 3077790 lpg1281 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095311.1 1410027 D 272624 CDS YP_095312.1 52841513 3077791 1410413..1411168 1 NC_002942.5 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1411168 surE 3077791 surE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stationary phase survival protein SurE YP_095312.1 1410413 D 272624 CDS YP_095313.1 52841514 3080334 1411187..1411930 1 NC_002942.5 lipoprotein NlpD 1411930 3080334 lpg1283 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein NlpD YP_095313.1 1411187 D 272624 CDS YP_095314.1 52841515 3080381 1411962..1413041 1 NC_002942.5 stationary phase specific sigma factor RpoS 1413041 rpoS 3080381 rpoS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stationary phase specific sigma factor RpoS YP_095314.1 1411962 D 272624 CDS YP_095315.1 52841516 3080383 complement(1413144..1414394) 1 NC_002942.5 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine; homogentisate 1,2-dioxygenase 1414394 3080383 lpg1285 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 homogentisate 1,2-dioxygenase YP_095315.1 1413144 R 272624 CDS YP_095316.1 52841517 3080386 1414540..1415283 1 NC_002942.5 hypothetical protein 1415283 3080386 lpg1286 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095316.1 1414540 D 272624 CDS YP_095317.1 52841518 3080309 1415283..1415807 1 NC_002942.5 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1415807 ruvC 3080309 ruvC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Holliday junction resolvase YP_095317.1 1415283 D 272624 CDS YP_095318.1 52841519 3080319 1415804..1416403 1 NC_002942.5 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1416403 ruvA 3080319 ruvA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Holliday junction DNA helicase RuvA YP_095318.1 1415804 D 272624 CDS YP_095319.1 52841520 3080333 1416453..1416773 1 NC_002942.5 hypothetical protein 1416773 3080333 lpg1289 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095319.1 1416453 D 272624 CDS YP_095320.1 52841521 3080328 complement(1416806..1418392) 1 NC_002942.5 hypothetical protein 1418392 3080328 lpg1290 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095320.1 1416806 R 272624 CDS YP_095321.1 52841522 3080264 complement(1418676..1420091) 1 NC_002942.5 two component sensor kinase 1420091 3080264 lpg1291 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component sensor kinase YP_095321.1 1418676 R 272624 CDS YP_095322.1 52841523 3080249 complement(1420088..1420765) 1 NC_002942.5 DNA-binding response regulator 1420765 3080249 lpg1292 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-binding response regulator YP_095322.1 1420088 R 272624 CDS YP_095323.1 52841524 3080257 complement(1420826..1421371) 1 NC_002942.5 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1421371 ispZ 3080257 ispZ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 intracellular septation protein A YP_095323.1 1420826 R 272624 CDS YP_095324.1 52841525 3080244 complement(1421614..1423053) 1 NC_002942.5 membrane bound lytic murein transglycosylase D 1423053 3080244 lpg1294 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane bound lytic murein transglycosylase D YP_095324.1 1421614 R 272624 CDS YP_095325.1 52841526 3080605 complement(1423168..1423932) 1 NC_002942.5 hydroxyacylglutathione hydrolase GloB 1423932 3080605 lpg1295 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydroxyacylglutathione hydrolase GloB YP_095325.1 1423168 R 272624 CDS YP_095326.1 52841527 3080238 complement(1423936..1424799) 1 NC_002942.5 protein involved in catabolism of external DNA 1424799 3080238 lpg1296 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein involved in catabolism of external DNA YP_095326.1 1423936 R 272624 CDS YP_095327.1 52841528 3080301 complement(1425272..1426126) 1 NC_002942.5 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1426126 folD 3080301 folD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_095327.1 1425272 R 272624 CDS YP_095328.1 52841529 3080308 complement(1426213..1426413) 1 NC_002942.5 hypothetical protein 1426413 3080308 lpg1298 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095328.1 1426213 R 272624 CDS YP_095329.1 52841530 3080296 1426682..1429123 1 NC_002942.5 transmembrane Tfp pilus assembly protein FimV (twitching motility) 1429123 3080296 lpg1299 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane Tfp pilus assembly protein FimV (twitching motility) YP_095329.1 1426682 D 272624 CDS YP_095330.1 52841531 3080342 complement(1429177..1429644) 1 NC_002942.5 hypothetical protein 1429644 3080342 lpg1300 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095330.1 1429177 R 272624 CDS YP_095331.1 52841532 3077798 complement(1429644..1430942) 1 NC_002942.5 oxidoreductase 1430942 3077798 lpg1301 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase YP_095331.1 1429644 R 272624 CDS YP_095332.1 52841533 3080436 1431186..1431974 1 NC_002942.5 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1431974 truA 3080436 truA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA pseudouridine synthase A YP_095332.1 1431186 D 272624 CDS YP_095333.1 52841534 3080584 1431975..1432598 1 NC_002942.5 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1432598 trpF 3080584 trpF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-(5'-phosphoribosyl)anthranilate isomerase YP_095333.1 1431975 D 272624 CDS YP_095334.1 52841535 3080344 1432600..1433799 1 NC_002942.5 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1433799 3080344 lpg1304 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophan synthase subunit beta YP_095334.1 1432600 D 272624 CDS YP_095335.1 52841536 3080397 1433825..1434643 1 NC_002942.5 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1434643 trpA 3080397 trpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophan synthase subunit alpha YP_095335.1 1433825 D 272624 CDS YP_095336.1 52841537 3080488 1434640..1436295 1 NC_002942.5 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1436295 glnS 3080488 glnS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutaminyl-tRNA synthetase YP_095336.1 1434640 D 272624 CDS YP_095337.1 52841538 3077818 1436305..1437675 1 NC_002942.5 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1437675 cysS 3077818 cysS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cysteinyl-tRNA synthetase YP_095337.1 1436305 D 272624 CDS YP_095338.1 52841539 3077944 1437841..1439760 1 NC_002942.5 sulfatase 1439760 3077944 lpg1308 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfatase YP_095338.1 1437841 D 272624 CDS YP_095339.1 52841540 3077813 1439890..1440204 1 NC_002942.5 hypothetical protein 1440204 3077813 lpg1309 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095339.1 1439890 D 272624 CDS YP_095340.1 52841541 3080562 complement(1440088..1440381) 1 NC_002942.5 hypothetical protein 1440381 3080562 lpg1310 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095340.1 1440088 R 272624 CDS YP_095341.1 52841542 3080371 1440128..1440397 1 NC_002942.5 hypothetical protein 1440397 3080371 lpg1311 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095341.1 1440128 D 272624 CDS YP_095342.1 52841543 3080331 1440709..1444116 1 NC_002942.5 similar to erythrocyte membrane-associated antigen; coiled-coil-containing protein 1444116 legC1 3080331 legC1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coiled-coil-containing protein YP_095342.1 1440709 D 272624 CDS YP_095343.1 52841544 3080320 complement(1444211..1444390) 1 NC_002942.5 transposase 1444390 3080320 lpg1313 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase YP_095343.1 1444211 R 272624 CDS YP_095344.1 52841545 3080326 complement(1444970..1445260) 1 NC_002942.5 hypothetical protein 1445260 3080326 lpg1314 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095344.1 1444970 R 272624 CDS YP_095345.1 52841546 3080593 complement(1445315..1446064) 1 NC_002942.5 transposase 1446064 3080593 lpg1315 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase YP_095345.1 1445315 R 272624 CDS YP_095346.1 52841547 3080348 complement(1446245..1447267) 1 NC_002942.5 hypothetical protein 1447267 3080348 lpg1316 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095346.1 1446245 R 272624 CDS YP_095347.1 52841548 3077655 complement(1447359..1448246) 1 NC_002942.5 hypothetical protein 1448246 3077655 lpg1317 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095347.1 1447359 R 272624 CDS YP_095348.1 52841549 3080544 1448796..1450778 1 NC_002942.5 hypothetical protein 1450778 3080544 lpg1318 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095348.1 1448796 D 272624 CDS YP_095349.1 52841550 3080092 complement(1450911..1452395) 1 NC_002942.5 type II protein secretion ATPase LspE 1452395 3080092 lpg1319 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II protein secretion ATPase LspE YP_095349.1 1450911 R 272624 CDS YP_095350.1 52841551 3077653 complement(1452399..1454774) 1 NC_002942.5 type II protein secretion LspD 1454774 3077653 lpg1320 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II protein secretion LspD YP_095350.1 1452399 R 272624 CDS YP_095351.1 52841552 3080412 1454875..1455975 1 NC_002942.5 oxidoreductase 1455975 3080412 lpg1321 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase YP_095351.1 1454875 D 272624 CDS YP_095352.1 52841553 3080070 complement(1455996..1458131) 1 NC_002942.5 adenylate cyclase 1458131 cyaA 3080070 cyaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylate cyclase YP_095352.1 1455996 R 272624 CDS YP_095353.1 52841554 3080590 complement(1458245..1459405) 1 NC_002942.5 drug resistance transporter Bcr/CflA 1459405 3080590 lpg1323 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 drug resistance transporter Bcr/CflA YP_095353.1 1458245 R 272624 CDS YP_095354.1 52841555 3077642 complement(1459402..1460616) 1 NC_002942.5 multidrug resistance efflux pump 1460616 3077642 lpg1324 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance efflux pump YP_095354.1 1459402 R 272624 CDS YP_095355.1 52841556 3080430 complement(1460609..1462408) 1 NC_002942.5 siderophore biosynthetic enzyme FrgA 1462408 frgA 3080430 frgA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 siderophore biosynthetic enzyme FrgA YP_095355.1 1460609 R 272624 CDS YP_095356.1 52841557 3080439 complement(1462484..1463569) 1 NC_002942.5 hypothetical protein 1463569 3080439 lpg1326 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095356.1 1462484 R 272624 CDS YP_095357.1 52841558 3080421 1463957..1464271 1 NC_002942.5 hypothetical protein 1464271 3080421 lpg1327 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095357.1 1463957 D 272624 CDS YP_095358.1 52841559 3080428 complement(1464351..1466816) 1 NC_002942.5 thaumatin domain-containing protein 1466816 legT 3080428 legT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thaumatin domain-containing protein YP_095358.1 1464351 R 272624 CDS YP_095359.1 52841560 3077644 complement(1466869..1468038) 1 NC_002942.5 hypothetical protein 1468038 3077644 lpg1329 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095359.1 1466869 R 272624 CDS YP_095360.1 52841561 3080497 complement(1468603..1470003) 1 NC_002942.5 protease Do 1470003 htrA 3080497 htrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protease Do YP_095360.1 1468603 R 272624 CDS YP_095361.1 52841562 3080423 complement(1469996..1470721) 1 NC_002942.5 hypothetical protein 1470721 3080423 lpg1332 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095361.1 1469996 R 272624 CDS YP_095362.1 52841563 3080346 complement(1470711..1471676) 1 NC_002942.5 ribosomal large subunit pseudouridine synthase D, RluD 1471676 rluD 3080346 rluD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosomal large subunit pseudouridine synthase D, RluD YP_095362.1 1470711 R 272624 CDS YP_095363.1 52841564 3077666 complement(1471676..1473019) 1 NC_002942.5 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1473019 3077666 lpg1334 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (dimethylallyl)adenosine tRNA methylthiotransferase YP_095363.1 1471676 R 272624 CDS YP_095364.1 52841565 3077662 complement(1473056..1474354) 1 NC_002942.5 major facilitator transporter 1474354 3077662 lpg1335 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator transporter YP_095364.1 1473056 R 272624 CDS YP_095365.1 52841566 3077668 complement(1474594..1475340) 1 NC_002942.5 enhanced entry protein EnhA 1475340 enhA 3077668 enhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhA YP_095365.1 1474594 R 272624 CDS YP_095366.1 52841567 3077669 complement(1475663..1476073) 1 NC_002942.5 flagellar protein FliS 1476073 fliS 3077669 fliS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar protein FliS YP_095366.1 1475663 R 272624 CDS YP_095367.1 52841568 3077670 complement(1476083..1477708) 1 NC_002942.5 flagellar hook associated protein 2 FliD 1477708 fliD 3077670 fliD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook associated protein 2 FliD YP_095367.1 1476083 R 272624 CDS YP_095368.1 52841569 3077675 complement(1477771..1478052) 1 NC_002942.5 hypothetical protein 1478052 3077675 lpg1339 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095368.1 1477771 R 272624 CDS YP_095369.1 52841570 3077678 complement(1478135..1479562) 1 NC_002942.5 structural flagella protein; flagellin 1479562 fliC 3077678 fliC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellin YP_095369.1 1478135 R 272624 CDS YP_095370.1 52841571 3078069 1479974..1480858 1 NC_002942.5 acetyl CoA carboxylase, carboxyltransferase subunit beta 1480858 accD 3078069 accD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl CoA carboxylase, carboxyltransferase subunit beta YP_095370.1 1479974 D 272624 CDS YP_095371.1 52841572 3077681 1480839..1482125 1 NC_002942.5 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1482125 folC 3077681 folC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_095371.1 1480839 D 272624 CDS YP_095372.1 52841573 3077686 1482122..1482892 1 NC_002942.5 hypothetical protein 1482892 3077686 lpg1343 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095372.1 1482122 D 272624 CDS YP_095373.1 52841574 3077688 1482895..1483428 1 NC_002942.5 colicin V 1483428 dedE 3077688 dedE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 colicin V YP_095373.1 1482895 D 272624 CDS YP_095374.1 52841575 3080273 complement(1483403..1484038) 1 NC_002942.5 nicotinate-nucleotide adenylyltransferase 1484038 3080273 lpg1345 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nicotinate-nucleotide adenylyltransferase YP_095374.1 1483403 R 272624 CDS YP_095375.1 52841576 3077859 complement(1484026..1485051) 1 NC_002942.5 DNA polymerase III subunit delta 1485051 holA 3077859 holA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III subunit delta YP_095375.1 1484026 R 272624 CDS YP_095376.1 52841577 3077866 complement(1485053..1485544) 1 NC_002942.5 rare lipoprotein B 1485544 3077866 lpg1347 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rare lipoprotein B YP_095376.1 1485053 R 272624 CDS YP_095377.1 52841578 3080267 complement(1485646..1488117) 1 NC_002942.5 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1488117 leuS 3080267 leuS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 leucyl-tRNA synthetase YP_095377.1 1485646 R 272624 CDS YP_095378.1 52841579 3080265 complement(1488183..1489718) 1 NC_002942.5 apolipoprotein N-acyltransferase 1489718 cutE 3080265 cutE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 apolipoprotein N-acyltransferase YP_095378.1 1488183 R 272624 CDS YP_095379.1 52841580 3080512 1489825..1490961 1 NC_002942.5 L-lysine dehydrogenase 1490961 3080512 lpg1350 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-lysine dehydrogenase YP_095379.1 1489825 D 272624 CDS YP_095380.1 52841581 3078375 1490971..1492491 1 NC_002942.5 piperidine-6-carboxylate dehydrogenase 1492491 3078375 lpg1351 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 piperidine-6-carboxylate dehydrogenase YP_095380.1 1490971 D 272624 CDS YP_095381.1 52841582 3079690 1492611..1494980 1 NC_002942.5 3-hydroxyacyl CoA dehydrogenase oxidoreductase/ 1494980 fadB 3079690 fadB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxyacyl CoA dehydrogenase oxidoreductase/ YP_095381.1 1492611 D 272624 CDS YP_095382.1 52841583 3079565 1494996..1496180 1 NC_002942.5 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1496180 fadA 3079565 fadA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl-CoA acetyltransferase YP_095382.1 1494996 D 272624 CDS YP_095383.1 52841584 3079987 complement(1496281..1497456) 1 NC_002942.5 hypothetical protein 1497456 3079987 lpg1354 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095383.1 1496281 R 272624 CDS YP_095384.1 52841585 3079783 complement(1497609..1500533) 1 NC_002942.5 conserved gene, named proteins SidG, LepC, Vng0394c; protein SidG 1500533 sidG 3079783 sidG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidG YP_095384.1 1497609 R 272624 CDS YP_095385.1 52841586 3079677 1501020..1502150 1 NC_002942.5 hypothetical protein 1502150 3079677 lpg1356 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095385.1 1501020 D 272624 CDS YP_095386.1 52841587 3079668 complement(1502289..1504667) 1 NC_002942.5 hypothetical protein 1504667 3079668 lpg1357 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095386.1 1502289 R 272624 CDS YP_095387.1 52841588 3079311 complement(1504982..1505950) 1 NC_002942.5 type II secretory pathway protein 1505950 xcpX 3079311 xcpX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein YP_095387.1 1504982 R 272624 CDS YP_095388.1 52841589 3079503 complement(1505937..1506554) 1 NC_002942.5 type II secretory pathway protein LspJ 1506554 xcpW 3079503 xcpW Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein LspJ YP_095388.1 1505937 R 272624 CDS YP_095389.1 52841590 3080106 complement(1506551..1506928) 1 NC_002942.5 type II secretory pathway protein LspI 1506928 3080106 lpg1360 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein LspI YP_095389.1 1506551 R 272624 CDS YP_095390.1 52841591 3080162 complement(1506925..1507479) 1 NC_002942.5 type II secretory pathway protein LspH 1507479 xcpU 3080162 xcpU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein LspH YP_095390.1 1506925 R 272624 CDS YP_095391.1 52841592 3080167 complement(1507397..1507819) 1 NC_002942.5 type II secretory pathway protein LspG 1507819 gspG 3080167 gspG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein LspG YP_095391.1 1507397 R 272624 CDS YP_095392.1 52841593 3080283 complement(1507923..1509122) 1 NC_002942.5 type II secretory pathway protein LspF 1509122 gspF 3080283 gspF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretory pathway protein LspF YP_095392.1 1507923 R 272624 CDS YP_095393.1 52841594 3080503 1509219..1510628 1 NC_002942.5 glutamine synthetase 1510628 glnA 3080503 glnA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine synthetase YP_095393.1 1509219 D 272624 CDS YP_095394.1 52841595 3080177 1510641..1511201 1 NC_002942.5 hypothetical protein 1511201 3080177 lpg1365 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095394.1 1510641 D 272624 CDS YP_095395.1 52841596 3080262 1511214..1511987 1 NC_002942.5 hypothetical protein 1511987 3080262 lpg1366 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095395.1 1511214 D 272624 CDS YP_095396.1 52841597 3080209 1512004..1512906 1 NC_002942.5 1-aminocyclopropane-1-carboxylate deaminase 1512906 3080209 lpg1367 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 1-aminocyclopropane-1-carboxylate deaminase YP_095396.1 1512004 D 272624 CDS YP_095397.1 52841598 3080322 1513119..1514696 1 NC_002942.5 hypothetical protein 1514696 3080322 lpg1368 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095397.1 1513119 D 272624 CDS YP_095398.1 52841599 3080181 1514897..1516768 1 NC_002942.5 molecular chaperone; heat shock protein 90 1516768 htpG 3080181 htpG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heat shock protein 90 YP_095398.1 1514897 D 272624 CDS YP_095399.1 52841600 3080164 complement(1516880..1517176) 1 NC_002942.5 hypothetical protein 1517176 fis 3080164 fis Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095399.1 1516880 R 272624 CDS YP_095400.1 52841601 3080186 complement(1517292..1518446) 1 NC_002942.5 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1518446 lpxB 3080186 lpxB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipid-A-disaccharide synthase YP_095400.1 1517292 R 272624 CDS YP_095401.1 52841602 3079288 complement(1518433..1519395) 1 NC_002942.5 oxidoreductase 1519395 3079288 lpg1372 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase YP_095401.1 1518433 R 272624 CDS YP_095402.1 52841603 3079114 1519616..1520191 1 NC_002942.5 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1520191 rnhB 3079114 rnhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease HII YP_095402.1 1519616 D 272624 CDS YP_095403.1 52841604 3080521 complement(1520302..1521420) 1 NC_002942.5 rod shape determining protein RodA 1521420 rodA 3080521 rodA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rod shape determining protein RodA YP_095403.1 1520302 R 272624 CDS YP_095404.1 52841605 3079522 complement(1521417..1523297) 1 NC_002942.5 penicillin binding protein 2 1523297 pbpA 3079522 pbpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 penicillin binding protein 2 YP_095404.1 1521417 R 272624 CDS YP_095405.1 52841606 3079523 complement(1523437..1523907) 1 NC_002942.5 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1523907 3079523 lpg1376 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rRNA large subunit methyltransferase YP_095405.1 1523437 R 272624 CDS YP_095406.1 52841607 3079532 complement(1523916..1524254) 1 NC_002942.5 hypothetical protein 1524254 3079532 lpg1377 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095406.1 1523916 R 272624 CDS YP_095407.1 52841608 3079542 complement(1524359..1525801) 1 NC_002942.5 proton/peptide symporter, POT family protein 1525801 3079542 lpg1378 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proton/peptide symporter, POT family protein YP_095407.1 1524359 R 272624 CDS YP_095408.1 52841609 3079495 1526021..1527688 1 NC_002942.5 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1527688 3079495 lpg1379 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 urocanate hydratase YP_095408.1 1526021 D 272624 CDS YP_095409.1 52841610 3079111 1527615..1529222 1 NC_002942.5 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 1529222 3079111 lpg1380 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 histidine ammonia-lyase YP_095409.1 1527615 D 272624 CDS YP_095410.1 52841611 3079525 1529236..1530639 1 NC_002942.5 aldehyde dehydrogenase 1530639 3079525 lpg1381 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aldehyde dehydrogenase YP_095410.1 1529236 D 272624 CDS YP_095411.1 52841612 3079502 1530636..1531445 1 NC_002942.5 short chain dehydrogenase 1531445 3079502 lpg1382 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase YP_095411.1 1530636 D 272624 CDS YP_095412.1 52841613 3080176 1531442..1531873 1 NC_002942.5 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1531873 rnhA 3080176 rnhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease H YP_095412.1 1531442 D 272624 CDS YP_095413.1 52841614 3079521 1531824..1532579 1 NC_002942.5 DNA polymerase III subunit epsilon 1532579 dnaQ 3079521 dnaQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III subunit epsilon YP_095413.1 1531824 D 272624 CDS YP_095414.1 52841615 3078062 complement(1532786..1533163) 1 NC_002942.5 hypothetical protein 1533163 3078062 lpg1385 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095414.1 1532786 R 272624 CDS YP_095415.1 52841616 3078081 1533360..1533833 1 NC_002942.5 enhanced entry protein EnhA 1533833 3078081 lpg1386 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhA YP_095415.1 1533360 D 272624 CDS YP_095416.1 52841617 3078770 1533945..1535354 1 NC_002942.5 hypothetical protein 1535354 3078770 lpg1387 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095416.1 1533945 D 272624 CDS YP_095417.1 52841618 3080456 complement(1535420..1535812) 1 NC_002942.5 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1535812 3080456 lpg1388 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 iron-sulfur cluster insertion protein ErpA YP_095417.1 1535420 R 272624 CDS YP_095418.1 52841619 3079635 complement(1535948..1537033) 1 NC_002942.5 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1537033 mnmA 3079635 mnmA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA-specific 2-thiouridylase MnmA YP_095418.1 1535948 R 272624 CDS YP_095419.1 52841620 3078922 1537306..1537734 1 NC_002942.5 hypothetical protein 1537734 3078922 lpg1390 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095419.1 1537306 D 272624 CDS YP_095420.1 52841621 3079949 1537820..1538011 1 NC_002942.5 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1538011 rpmF 3079949 rpmF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L32 YP_095420.1 1537820 D 272624 CDS YP_095421.1 52841622 3080443 1538017..1539045 1 NC_002942.5 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1539045 plsX 3080443 plsX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerol-3-phosphate acyltransferase PlsX YP_095421.1 1538017 D 272624 CDS YP_095422.1 52841623 3078893 1539042..1539995 1 NC_002942.5 3-oxoacyl-ACP synthase 1539995 fabH 3078893 fabH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_095422.1 1539042 D 272624 CDS YP_095423.1 52841624 3078657 1540022..1540969 1 NC_002942.5 malonyl CoA-ACP transacylase 1540969 3078657 lpg1394 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malonyl CoA-ACP transacylase YP_095423.1 1540022 D 272624 CDS YP_095424.1 52841625 3078429 1540981..1541727 1 NC_002942.5 3-oxoacyl-ACP reductase 1541727 fabG 3078429 fabG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP reductase YP_095424.1 1540981 D 272624 CDS YP_095425.1 52841626 3079039 1541812..1542060 1 NC_002942.5 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1542060 acpP 3079039 acpP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl carrier protein YP_095425.1 1541812 D 272624 CDS YP_095426.1 52841627 3077910 1542080..1543318 1 NC_002942.5 beta-ketoacyl-ACP synthase 1543318 fabF1 3077910 fabF1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 beta-ketoacyl-ACP synthase YP_095426.1 1542080 D 272624 CDS YP_095427.1 52841628 3077633 1543319..1544317 1 NC_002942.5 conserved gene, also probably aminodeoxychorismate lyase; ABC transporter substrate-binding protein 1544317 3077633 lpg1398 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter substrate-binding protein YP_095427.1 1543319 D 272624 CDS YP_095428.1 52841629 3080095 1544317..1544955 1 NC_002942.5 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1544955 tmk 3080095 tmk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thymidylate kinase YP_095428.1 1544317 D 272624 CDS YP_095429.1 52841630 3079784 1544952..1545857 1 NC_002942.5 DNA polymerase III, delta prime subunit 1545857 holB 3079784 holB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III, delta prime subunit YP_095429.1 1544952 D 272624 CDS YP_095430.1 52841631 3080462 1545984..1546325 1 NC_002942.5 type 4 fimbrial biogenesis protein PilZ 1546325 pilZ 3080462 pilZ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type 4 fimbrial biogenesis protein PilZ YP_095430.1 1545984 D 272624 CDS YP_095431.1 52841632 3079725 1546357..1547169 1 NC_002942.5 deoxyribonuclease TatD 1547169 3079725 lpg1402 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyribonuclease TatD YP_095431.1 1546357 D 272624 CDS YP_095432.1 52841633 3079736 1547281..1548381 1 NC_002942.5 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1548381 anmK 3079736 anmK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 anhydro-N-acetylmuramic acid kinase YP_095432.1 1547281 D 272624 CDS YP_095433.1 52841634 3080549 1548437..1549729 1 NC_002942.5 major facilitator family transporter 1549729 3080549 lpg1404 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_095433.1 1548437 D 272624 CDS YP_095434.1 52841635 3080453 complement(1549805..1551085) 1 NC_002942.5 multidrug translocase MdfA, chloramphenicol resistance pump Cmr 1551085 cmr 3080453 cmr Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug translocase MdfA, chloramphenicol resistance pump Cmr YP_095434.1 1549805 R 272624 CDS YP_095435.1 52841636 3077950 1551307..1552482 1 NC_002942.5 glycosyltransferase 1552482 3077950 lpg1406 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyltransferase YP_095435.1 1551307 D 272624 CDS YP_095436.1 52841637 3079694 complement(1552519..1553904) 1 NC_002942.5 dolichol monophosphate mannose synthase 1553904 3079694 lpg1407 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dolichol monophosphate mannose synthase YP_095436.1 1552519 R 272624 CDS YP_095437.1 52841638 3079889 1553994..1555145 1 NC_002942.5 choline kinase 1555145 licA 3079889 licA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 choline kinase YP_095437.1 1553994 D 272624 CDS YP_095438.1 52841639 3078802 complement(1555198..1555968) 1 NC_002942.5 hypothetical protein 1555968 3078802 lpg1409 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095438.1 1555198 R 272624 CDS YP_095439.1 52841640 3078711 1556214..1556810 1 NC_002942.5 hypothetical protein 1556810 3078711 lpg1410 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095439.1 1556214 D 272624 CDS YP_095440.1 52841641 3078121 1557151..1557861 1 NC_002942.5 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1557861 adk 3078121 adk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylate kinase YP_095440.1 1557151 D 272624 CDS YP_095441.1 52841642 3078438 1557870..1558232 1 NC_002942.5 thioredoxin 1558232 trxA3 3078438 trxA3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thioredoxin YP_095441.1 1557870 D 272624 CDS YP_095442.1 52841643 3080410 complement(1558192..1559712) 1 NC_002942.5 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 1559712 glpD 3080410 glpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerol-3-phosphate dehydrogenase YP_095442.1 1558192 R 272624 CDS YP_095443.1 52841644 3080489 1559774..1561249 1 NC_002942.5 glycerol kinase 1561249 3080489 lpg1414 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerol kinase YP_095443.1 1559774 D 272624 CDS YP_095444.1 52841645 3078851 complement(1561343..1562614) 1 NC_002942.5 citrate synthase 1562614 gltA 3078851 gltA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 citrate synthase YP_095444.1 1561343 R 272624 CDS YP_095445.1 52841646 3078029 1562840..1563721 1 NC_002942.5 purine nucleoside phosphorylase II 1563721 3078029 lpg1416 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 purine nucleoside phosphorylase II YP_095445.1 1562840 D 272624 CDS YP_095446.1 52841647 3078366 1563781..1566396 1 NC_002942.5 DNA gyrase subunit A 1566396 gyrA 3078366 gyrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA gyrase subunit A YP_095446.1 1563781 D 272624 CDS YP_095447.1 52841648 3078021 1566371..1567477 1 NC_002942.5 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1567477 serC 3078021 serC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoserine aminotransferase YP_095447.1 1566371 D 272624 CDS YP_095448.1 52841649 3078232 1567483..1568784 1 NC_002942.5 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1568784 3078232 lpg1419 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-phosphoshikimate 1-carboxyvinyltransferase YP_095448.1 1567483 D 272624 CDS YP_095449.1 52841650 3080546 1568781..1569476 1 NC_002942.5 cytidylate kinase 1569476 cmk 3080546 cmk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytidylate kinase YP_095449.1 1568781 D 272624 CDS YP_095450.2 161723255 3080458 1569542..1571218 1 NC_002942.5 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1571218 rpsA 3080458 rpsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S1 YP_095450.2 1569542 D 272624 CDS YP_095451.1 52841652 3078704 1571331..1571621 1 NC_002942.5 hypothetical protein 1571621 3078704 lpg1422 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095451.1 1571331 D 272624 CDS YP_095452.1 52841653 3078383 1571668..1572837 1 NC_002942.5 tetratricopeptide repeat protein 1572837 3078383 lpg1423 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tetratricopeptide repeat protein YP_095452.1 1571668 D 272624 CDS YP_095453.1 52841654 3078130 1573101..1574216 1 NC_002942.5 aminotransferase 1574216 3078130 lpg1424 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminotransferase YP_095453.1 1573101 D 272624 CDS YP_095454.1 52841655 3078166 1574217..1574906 1 NC_002942.5 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1574906 pyrF 3078166 pyrF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 orotidine 5'-phosphate decarboxylase YP_095454.1 1574217 D 272624 CDS YP_095455.1 52841656 3078231 1575093..1577747 1 NC_002942.5 hypothetical protein 1577747 3078231 lpg1426 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095455.1 1575093 D 272624 CDS YP_095456.1 52841657 3077674 1577692..1578471 1 NC_002942.5 short chain dehydrogenase 1578471 3077674 lpg1427 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase YP_095456.1 1577692 D 272624 CDS YP_095457.1 52841658 3077834 1578477..1578965 1 NC_002942.5 Tfp type 4 fimbrial pilin related signal peptide protein 1578965 3077834 lpg1428 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Tfp type 4 fimbrial pilin related signal peptide protein YP_095457.1 1578477 D 272624 CDS YP_095458.1 52841659 3078073 1579078..1579614 1 NC_002942.5 hypothetical protein 1579614 3078073 lpg1429 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095458.1 1579078 D 272624 CDS YP_095459.1 52841660 3078278 1579611..1580459 1 NC_002942.5 UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 1580459 ubiA 3078278 ubiA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-hydroxybenzoate polyprenyltransferase YP_095459.1 1579611 D 272624 CDS YP_095460.1 52841661 3077845 complement(1580593..1580991) 1 NC_002942.5 hypothetical protein 1580991 3077845 lpg1431 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095460.1 1580593 R 272624 CDS YP_095461.1 52841662 3078082 complement(1581071..1582867) 1 NC_002942.5 FAD linked oxidase 1582867 3078082 lpg1432 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 FAD linked oxidase YP_095461.1 1581071 R 272624 CDS YP_095462.1 52841663 3079595 complement(1582897..1583661) 1 NC_002942.5 2-deoxyribose-5-phosphate aldolase 1583661 deoC 3079595 deoC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-deoxyribose-5-phosphate aldolase YP_095462.1 1582897 R 272624 CDS YP_095463.1 52841664 3078401 complement(1583658..1584497) 1 NC_002942.5 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1584497 xapA 3078401 xapA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 purine nucleoside phosphorylase YP_095463.1 1583658 R 272624 CDS YP_095464.1 52841665 3078046 complement(1584510..1584905) 1 NC_002942.5 cytidine deaminase 1584905 cdd 3078046 cdd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytidine deaminase YP_095464.1 1584510 R 272624 CDS YP_095465.1 52841666 3079594 complement(1584944..1585762) 1 NC_002942.5 hypothetical protein 1585762 3079594 lpg1436 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095465.1 1584944 R 272624 CDS YP_095466.1 52841667 3078181 complement(1585925..1587319) 1 NC_002942.5 sensor histidine kinase CpxA 1587319 cpxA 3078181 cpxA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor histidine kinase CpxA YP_095466.1 1585925 R 272624 CDS YP_095467.1 52841668 3078361 complement(1587285..1587965) 1 NC_002942.5 transcriptional regulatory protein CpxR 1587965 cpxR 3078361 cpxR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulatory protein CpxR YP_095467.1 1587285 R 272624 CDS YP_095468.1 52841669 3078119 complement(1587973..1588863) 1 NC_002942.5 Mg2+ and Co2+ transporter CorC 1588863 3078119 lpg1439 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Mg2+ and Co2+ transporter CorC YP_095468.1 1587973 R 272624 CDS YP_095469.1 52841670 3078199 complement(1588823..1589299) 1 NC_002942.5 metal dependent hydrolase 1589299 3078199 lpg1440 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metal dependent hydrolase YP_095469.1 1588823 R 272624 CDS YP_095470.1 52841671 3078266 complement(1589296..1590246) 1 NC_002942.5 phosphate starvation-inducible protein PhoH 1590246 3078266 lpg1441 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphate starvation-inducible protein PhoH YP_095470.1 1589296 R 272624 CDS YP_095471.1 52841672 3077680 1590516..1591364 1 NC_002942.5 metal dependent phosphoesterase 1591364 3077680 lpg1442 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metal dependent phosphoesterase YP_095471.1 1590516 D 272624 CDS YP_095472.1 52841673 3078180 1591316..1591981 1 NC_002942.5 translation factor 1591981 3078180 lpg1443 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 translation factor YP_095472.1 1591316 D 272624 CDS YP_095473.1 52841674 3078358 1592224..1593441 1 NC_002942.5 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1593441 trpS 3078358 trpS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tryptophanyl-tRNA synthetase YP_095473.1 1592224 D 272624 CDS YP_095474.1 52841675 3078290 1593441..1594232 1 NC_002942.5 hypothetical protein 1594232 3078290 lpg1445 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095474.1 1593441 D 272624 CDS YP_095475.1 52841676 3079507 1594225..1594815 1 NC_002942.5 hypothetical protein 1594815 3079507 lpg1446 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095475.1 1594225 D 272624 CDS YP_095476.1 52841677 3079506 1594805..1595551 1 NC_002942.5 pseudouridine synthase 1595551 3079506 lpg1447 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pseudouridine synthase YP_095476.1 1594805 D 272624 CDS YP_095477.1 52841678 3079500 1595787..1596572 1 NC_002942.5 transcriptional regulator 1596572 3079500 lpg1448 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator YP_095477.1 1595787 D 272624 CDS YP_095478.1 52841679 3079106 1596957..1599569 1 NC_002942.5 hypothetical protein 1599569 3079106 lpg1449 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095478.1 1596957 D 272624 CDS YP_095479.1 52841680 3079497 1599656..1600648 1 NC_002942.5 iron/ascorbate oxidoreductase 1600648 3079497 lpg1450 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 iron/ascorbate oxidoreductase YP_095479.1 1599656 D 272624 CDS YP_095480.1 52841681 3079496 complement(1600790..1601101) 1 NC_002942.5 hypothetical protein 1601101 3079496 lpg1451 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095480.1 1600790 R 272624 CDS YP_095481.1 52841682 3078450 1601435..1602322 1 NC_002942.5 lipase A 1602322 3078450 lpg1452 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipase A YP_095481.1 1601435 D 272624 CDS YP_095482.1 52841683 3080053 1602449..1602967 1 NC_002942.5 hypothetical protein 1602967 3080053 lpg1453 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095482.1 1602449 D 272624 CDS YP_095483.1 52841684 3080003 complement(1603092..1604477) 1 NC_002942.5 multidrug efflux protein 1604477 3080003 lpg1454 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug efflux protein YP_095483.1 1603092 R 272624 CDS YP_095484.1 52841685 3078442 complement(1604506..1605762) 1 NC_002942.5 phospholipase C 1605762 3078442 lpg1455 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospholipase C YP_095484.1 1604506 R 272624 CDS YP_095485.1 52841686 3080012 1605883..1607217 1 NC_002942.5 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 1607217 rumA 3080012 rumA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 23S rRNA 5-methyluridine methyltransferase YP_095485.1 1605883 D 272624 CDS YP_095486.1 52841687 3080031 1607223..1609427 1 NC_002942.5 GTP pyrophosphokinase 1609427 relA 3080031 relA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP pyrophosphokinase YP_095486.1 1607223 D 272624 CDS YP_095487.1 52841688 3080082 complement(1609468..1609833) 1 NC_002942.5 hypothetical protein 1609833 3080082 lpg1458 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095487.1 1609468 R 272624 CDS YP_095488.1 52841689 3078349 1609892..1611085 1 NC_002942.5 aminotransferase 1611085 yfdZ 3078349 yfdZ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminotransferase YP_095488.1 1609892 D 272624 CDS YP_095489.1 52841690 3079681 1611090..1611899 1 NC_002942.5 hypothetical protein 1611899 3079681 lpg1460 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095489.1 1611090 D 272624 CDS YP_095490.1 52841691 3078459 1611889..1613628 1 NC_002942.5 ssDNA-binding protein 1613628 recJ 3078459 recJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ssDNA-binding protein YP_095490.1 1611889 D 272624 CDS YP_095491.1 52841692 3079018 1613697..1614701 1 NC_002942.5 tRNA-dihydrouridine synthase A 1614701 3079018 lpg1462 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA-dihydrouridine synthase A YP_095491.1 1613697 D 272624 CDS YP_095492.2 161723254 3079660 1614802..1617492 1 NC_002942.5 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 1617492 secA 3079660 secA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecA YP_095492.2 1614802 D 272624 CDS YP_095493.1 52841694 3078621 1617735..1617893 1 NC_002942.5 hypothetical protein 1617893 3078621 lpg1464 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095493.1 1617735 D 272624 CDS YP_095494.1 52841695 3078465 1618097..1618927 1 NC_002942.5 hypothetical protein 1618927 3078465 lpg1465 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095494.1 1618097 D 272624 CDS YP_095495.1 52841696 3079679 complement(1618972..1619718) 1 NC_002942.5 hypothetical protein 1619718 3079679 lpg1466 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095495.1 1618972 R 272624 CDS YP_095496.1 52841697 3079972 complement(1619956..1620579) 1 NC_002942.5 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1620579 coaE 3079972 coaE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dephospho-CoA kinase YP_095496.1 1619956 R 272624 CDS YP_095497.1 52841698 3080627 complement(1620533..1621006) 1 NC_002942.5 hypothetical protein 1621006 3080627 lpg1468 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095497.1 1620533 R 272624 CDS YP_095498.1 52841699 3078648 complement(1621003..1622601) 1 NC_002942.5 hypothetical protein 1622601 3078648 lpg1469 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095498.1 1621003 R 272624 CDS YP_095499.1 52841700 3080036 1622738..1624399 1 NC_002942.5 serine-type D-Ala-D-Ala carboxypeptidase 1624399 3080036 lpg1470 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine-type D-Ala-D-Ala carboxypeptidase YP_095499.1 1622738 D 272624 CDS YP_095500.1 52841701 3078515 complement(1624710..1626092) 1 NC_002942.5 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1626092 bioA 3078515 bioA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_095500.1 1624710 R 272624 CDS YP_095501.1 52841702 3079940 1626117..1627064 1 NC_002942.5 biotin synthase 1627064 3079940 lpg1472 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biotin synthase YP_095501.1 1626117 D 272624 CDS YP_095502.1 52841703 3080169 1627065..1628210 1 NC_002942.5 8-amino-7-oxononanoate synthase 1628210 bioF 3080169 bioF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 8-amino-7-oxononanoate synthase YP_095502.1 1627065 D 272624 CDS YP_095503.1 52841704 3078773 1628191..1628910 1 NC_002942.5 biotin biosynthesis protein BioH 1628910 bioH 3078773 bioH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biotin biosynthesis protein BioH YP_095503.1 1628191 D 272624 CDS YP_095504.1 52841705 3079622 1628907..1629545 1 NC_002942.5 dethiobiotin synthetase 1629545 bioD 3079622 bioD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dethiobiotin synthetase YP_095504.1 1628907 D 272624 CDS YP_095505.1 52841706 3079867 1629680..1629994 1 NC_002942.5 hypothetical protein 1629994 3079867 lpg1476 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095505.1 1629680 D 272624 CDS YP_095506.1 52841707 3079017 1629991..1630620 1 NC_002942.5 transmembrane protein 1630620 3079017 lpg1477 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095506.1 1629991 D 272624 CDS YP_095507.1 52841708 3078641 1630639..1632420 1 NC_002942.5 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1632420 aspS 3078641 aspS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartyl-tRNA synthetase YP_095507.1 1630639 D 272624 CDS YP_095508.1 52841709 3080550 1632395..1635343 1 NC_002942.5 hypothetical protein 1635343 3080550 lpg1479 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095508.1 1632395 D 272624 CDS YP_095509.1 52841710 3079720 1635309..1635980 1 NC_002942.5 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 1635980 mutH 3079720 mutH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA mismatch repair protein YP_095509.1 1635309 D 272624 CDS YP_095510.1 52841711 3079767 complement(1636053..1637093) 1 NC_002942.5 hypothetical protein 1637093 3079767 lpg1481 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095510.1 1636053 R 272624 CDS YP_095511.1 52841712 3079090 complement(1637292..1638128) 1 NC_002942.5 hypothetical protein 1638128 3079090 lpg1482 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095511.1 1637292 R 272624 CDS YP_095512.1 52841713 3079079 1638274..1639863 1 NC_002942.5 similar to ovarian-specific serine/threonine-protein kinase; serine/threonine-protein kinase 1639863 legK1 3079079 legK1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine/threonine-protein kinase YP_095512.1 1638274 D 272624 CDS YP_095513.1 52841714 3079279 complement(1639917..1640726) 1 NC_002942.5 hypothetical protein 1640726 3079279 lpg1484 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095513.1 1639917 R 272624 CDS YP_095514.1 52841715 3079082 complement(1640925..1641326) 1 NC_002942.5 hypothetical protein 1641326 3079082 lpg1485 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095514.1 1640925 R 272624 CDS YP_095515.1 52841716 3079411 complement(1641412..1641933) 1 NC_002942.5 transcription regulator AsnC 1641933 3079411 lpg1486 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription regulator AsnC YP_095515.1 1641412 R 272624 CDS YP_095516.1 52841717 3079418 1642053..1642583 1 NC_002942.5 acetyltransferase 1642583 3079418 lpg1487 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_095516.1 1642053 D 272624 CDS YP_095517.1 52841718 3079790 1642834..1645431 1 NC_002942.5 conserved gene; similar to surface antigen of Plasmodium and Entamoeba; coiled-coil-containing protein 1645431 legC5 3079790 legC5 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coiled-coil-containing protein YP_095517.1 1642834 D 272624 CDS YP_095518.1 52841719 3080545 1645642..1646673 1 NC_002942.5 hypothetical protein 1646673 3080545 lpg1489 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095518.1 1645642 D 272624 CDS YP_095519.1 52841720 3078974 1646838..1648163 1 NC_002942.5 adenylate cyclase 1648163 cyaA 3078974 cyaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenylate cyclase YP_095519.1 1646838 D 272624 CDS YP_095520.1 52841721 3077836 1648274..1649515 1 NC_002942.5 hypothetical protein 1649515 3077836 lpg1491 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095520.1 1648274 D 272624 CDS YP_095521.1 52841722 3079214 complement(1649569..1650591) 1 NC_002942.5 spectinomycin phosphotransferase 1650591 3079214 lpg1492 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 spectinomycin phosphotransferase YP_095521.1 1649569 R 272624 CDS YP_095522.1 52841723 3079776 1650736..1650954 1 NC_002942.5 hypothetical protein 1650954 3079776 lpg1493 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095522.1 1650736 D 272624 CDS YP_095523.1 52841724 3079724 complement(1650968..1651390) 1 NC_002942.5 hypothetical protein 1651390 3079724 lpg1494 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095523.1 1650968 R 272624 CDS YP_095524.1 52841725 3079421 1651437..1651730 1 NC_002942.5 hypothetical protein 1651730 3079421 lpg1495 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095524.1 1651437 D 272624 CDS YP_095525.1 52841726 3080066 1652066..1653862 1 NC_002942.5 hypothetical protein 1653862 3080066 lpg1496 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095525.1 1652066 D 272624 CDS YP_095526.1 52841727 3080017 1654079..1656781 1 NC_002942.5 aminopeptidase 1656781 pepN 3080017 pepN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminopeptidase YP_095526.1 1654079 D 272624 CDS YP_095527.1 52841728 3079653 complement(1656922..1657860) 1 NC_002942.5 hypothetical protein 1657860 3079653 lpg1498 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095527.1 1656922 R 272624 CDS YP_095528.1 52841729 3080098 complement(1657932..1658474) 1 NC_002942.5 hypothetical protein 1658474 3080098 lpg1499 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095528.1 1657932 R 272624 CDS YP_095529.1 52841730 3080491 complement(1658523..1659224) 1 NC_002942.5 oxidoreductase, short chain dehydrogenase/reductase 1659224 3080491 lpg1500 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase, short chain dehydrogenase/reductase YP_095529.1 1658523 R 272624 CDS YP_095530.1 52841731 3080357 complement(1659724..1660188) 1 NC_002942.5 N-acetyltransferase 1660188 3080357 lpg1501 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-acetyltransferase YP_095530.1 1659724 R 272624 CDS YP_095531.1 52841732 3080621 complement(1660524..1661963) 1 NC_002942.5 dihydrolipoamide dehydrogenase 1661963 lpdA 3080621 lpdA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrolipoamide dehydrogenase YP_095531.1 1660524 R 272624 CDS YP_095532.2 161723253 3080561 complement(1662037..1663671) 1 NC_002942.5 dihydrolipoamide acetyltransferase 1663671 aceF 3080561 aceF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrolipoamide acetyltransferase YP_095532.2 1662037 R 272624 CDS YP_095533.1 52841734 3080378 complement(1663729..1666410) 1 NC_002942.5 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1666410 aceE 3080378 aceE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate dehydrogenase subunit E1 YP_095533.1 1663729 R 272624 CDS YP_095534.1 52841735 3080356 complement(1666420..1666809) 1 NC_002942.5 hypothetical protein 1666809 3080356 lpg1505 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095534.1 1666420 R 272624 CDS YP_095535.1 52841736 3078437 complement(1666848..1667627) 1 NC_002942.5 inner membrane protein AmpE 1667627 3078437 lpg1506 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inner membrane protein AmpE YP_095535.1 1666848 R 272624 CDS YP_095536.1 52841737 3078346 complement(1667605..1668777) 1 NC_002942.5 sodium/hydrogen antiporter 1668777 3078346 lpg1507 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sodium/hydrogen antiporter YP_095536.1 1667605 R 272624 CDS YP_095537.1 52841738 3078949 complement(1669097..1669918) 1 NC_002942.5 rare lipoprotein A 1669918 3078949 lpg1508 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rare lipoprotein A YP_095537.1 1669097 R 272624 CDS YP_095538.1 52841739 3078929 1670045..1671337 1 NC_002942.5 D-alanyl-D-alanine carboxypeptidase 1671337 3078929 lpg1509 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanyl-D-alanine carboxypeptidase YP_095538.1 1670045 D 272624 CDS YP_095539.1 52841740 3079049 1671350..1672186 1 NC_002942.5 D-alanine-aminotransferase 1672186 3079049 lpg1510 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanine-aminotransferase YP_095539.1 1671350 D 272624 CDS YP_095540.1 52841741 3079341 1672453..1673052 1 NC_002942.5 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 1673052 lipB 3079341 lipB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoyltransferase YP_095540.1 1672453 D 272624 CDS YP_095541.1 52841742 3079481 1673062..1675098 1 NC_002942.5 DedA/PAP2 domain-containing protein 1675098 3079481 lpg1512 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DedA/PAP2 domain-containing protein YP_095541.1 1673062 D 272624 CDS YP_095542.1 52841743 3079625 1675215..1675829 1 NC_002942.5 type I secretion system LssZ 1675829 3079625 lpg1513 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type I secretion system LssZ YP_095542.1 1675215 D 272624 CDS YP_095543.1 52841744 3080078 1675884..1676615 1 NC_002942.5 lipoprotein 1676615 3080078 lpg1514 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein YP_095543.1 1675884 D 272624 CDS YP_095544.1 52841745 3080073 1676654..1678285 1 NC_002942.5 toxin secretion ATP-binding protein 1678285 3080073 lpg1515 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 toxin secretion ATP-binding protein YP_095544.1 1676654 D 272624 CDS YP_095545.1 52841746 3079436 1678273..1678854 1 NC_002942.5 ABC transporter ATP-binding/permease fusion protein 1678854 3079436 lpg1516 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding/permease fusion protein YP_095545.1 1678273 D 272624 CDS YP_095546.1 52841747 3078710 1678858..1679994 1 NC_002942.5 HlyD family secretion protein 1679994 3078710 lpg1517 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HlyD family secretion protein YP_095546.1 1678858 D 272624 CDS YP_095547.1 52841748 3078225 1680081..1682630 1 NC_002942.5 sensory box protein 1682630 3078225 lpg1518 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_095547.1 1680081 D 272624 CDS YP_095548.1 52841749 3077869 complement(1682632..1683201) 1 NC_002942.5 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1683201 3077869 lpg1519 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypoxanthine-guanine phosphoribosyltransferase YP_095548.1 1682632 R 272624 CDS YP_095549.1 52841750 3080117 complement(1683244..1683570) 1 NC_002942.5 hypothetical protein 1683570 3080117 lpg1520 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095549.1 1683244 R 272624 CDS YP_095550.1 52841751 3077697 complement(1683753..1684496) 1 NC_002942.5 methyl-transferase 1684496 3077697 lpg1521 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methyl-transferase YP_095550.1 1683753 R 272624 CDS YP_095551.1 52841752 3080594 1684755..1686479 1 NC_002942.5 (type IV) pilus assembly protein PilB 1686479 pilB 3080594 pilB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (type IV) pilus assembly protein PilB YP_095551.1 1684755 D 272624 CDS YP_095552.1 52841753 3078386 1686485..1687705 1 NC_002942.5 (type IV) pilus assembly protein PilC 1687705 pilC 3078386 pilC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (type IV) pilus assembly protein PilC YP_095552.1 1686485 D 272624 CDS YP_095553.1 52841754 3080565 1687745..1688614 1 NC_002942.5 type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD 1688614 pilD 3080565 pilD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD YP_095553.1 1687745 D 272624 CDS YP_095554.1 52841755 3077858 complement(1688628..1689866) 1 NC_002942.5 CAAX amino terminal protease 1689866 3077858 lpg1525 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CAAX amino terminal protease YP_095554.1 1688628 R 272624 CDS YP_095555.1 52841756 3080628 complement(1689941..1690534) 1 NC_002942.5 hypothetical protein 1690534 3080628 lpg1526 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095555.1 1689941 R 272624 CDS YP_095556.1 52841757 3077757 complement(1690550..1691005) 1 NC_002942.5 hypothetical protein 1691005 3077757 lpg1527 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095556.1 1690550 R 272624 CDS YP_095557.1 52841758 3077851 1691139..1691954 1 NC_002942.5 hypothetical protein 1691954 3077851 lpg1528 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095557.1 1691139 D 272624 CDS YP_095558.1 52841759 3077755 complement(1692079..1693551) 1 NC_002942.5 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 1693551 prpD 3077755 prpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-methylcitrate dehydratase YP_095558.1 1692079 R 272624 CDS YP_095559.1 52841760 3077830 complement(1693529..1694647) 1 NC_002942.5 2-methylcitrate synthase 1694647 3077830 lpg1530 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-methylcitrate synthase YP_095559.1 1693529 R 272624 CDS YP_095560.1 52841761 3077844 complement(1694853..1695644) 1 NC_002942.5 phenazine biosynthesis PhzF 1695644 3077844 lpg1531 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phenazine biosynthesis PhzF YP_095560.1 1694853 R 272624 CDS YP_095561.1 52841762 3080490 complement(1695724..1697724) 1 NC_002942.5 peptidase 1697724 3080490 lpg1532 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidase YP_095561.1 1695724 R 272624 CDS YP_095562.1 52841763 3080229 complement(1697717..1699333) 1 NC_002942.5 POT family peptide transport protein 1699333 ydgR 3080229 ydgR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 POT family peptide transport protein YP_095562.1 1697717 R 272624 CDS YP_095563.1 52841764 3080291 complement(1699656..1700957) 1 NC_002942.5 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1700957 hemL 3080291 hemL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamate-1-semialdehyde aminotransferase YP_095563.1 1699656 R 272624 CDS YP_095564.1 52841765 3077773 1701368..1701544 1 NC_002942.5 rubredoxin (rubredoxin-type Fe(Cys)4 protein) 1701544 3077773 lpg1535 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rubredoxin (rubredoxin-type Fe(Cys)4 protein) YP_095564.1 1701368 D 272624 CDS YP_095565.1 52841766 3078058 complement(1701541..1701963) 1 NC_002942.5 transmembrane protein 1701963 3078058 lpg1536 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095565.1 1701541 R 272624 CDS YP_095566.1 52841767 3077831 complement(1701966..1702697) 1 NC_002942.5 transporter 1702697 3077831 lpg1537 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter YP_095566.1 1701966 R 272624 CDS YP_095567.1 52841768 3077855 1702965..1704275 1 NC_002942.5 poly(A) polymerase 1704275 pcnB 3077855 pcnB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 poly(A) polymerase YP_095567.1 1702965 D 272624 CDS YP_095568.1 52841769 3077829 1704272..1704697 1 NC_002942.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1704697 3077829 lpg1539 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_095568.1 1704272 D 272624 CDS YP_095569.1 52841770 3077843 1704752..1705174 1 NC_002942.5 universal stress protein A 1705174 3077843 lpg1540 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 universal stress protein A YP_095569.1 1704752 D 272624 CDS YP_095570.1 52841771 3077763 complement(1705239..1706627) 1 NC_002942.5 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1706627 engA 3077763 engA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP-binding protein EngA YP_095570.1 1705239 R 272624 CDS YP_095571.1 52841772 3077850 complement(1706632..1707795) 1 NC_002942.5 PQQ WD-40-like repeat-containing protein 1707795 3077850 lpg1542 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 PQQ WD-40-like repeat-containing protein YP_095571.1 1706632 R 272624 CDS YP_095572.1 52841773 3077761 complement(1707811..1708485) 1 NC_002942.5 transmembrane protein 1708485 3077761 lpg1543 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095572.1 1707811 R 272624 CDS YP_095573.1 52841774 3077832 complement(1708503..1709783) 1 NC_002942.5 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1709783 hisS 3077832 hisS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 histidyl-tRNA synthetase YP_095573.1 1708503 R 272624 CDS YP_095574.1 52841775 3077751 complement(1709773..1710342) 1 NC_002942.5 DNA-binding protein 1710342 3077751 lpg1545 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-binding protein YP_095574.1 1709773 R 272624 CDS YP_095575.1 52841776 3077762 complement(1710317..1711099) 1 NC_002942.5 fimbrial biogenesis and twitching motility protein PilF 1711099 3077762 lpg1546 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fimbrial biogenesis and twitching motility protein PilF YP_095575.1 1710317 R 272624 CDS YP_095576.1 52841777 3077837 complement(1711279..1712439) 1 NC_002942.5 radical SAM protein 1712439 3077837 lpg1547 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 radical SAM protein YP_095576.1 1711279 R 272624 CDS YP_095577.1 52841778 3077826 complement(1712448..1712924) 1 NC_002942.5 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1712924 ndk 3077826 ndk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleoside diphosphate kinase YP_095577.1 1712448 R 272624 CDS YP_095578.1 52841779 3077835 complement(1713008..1713892) 1 NC_002942.5 hypothetical protein 1713892 3077835 lpg1549 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095578.1 1713008 R 272624 CDS YP_095579.1 52841780 3077839 1713954..1714589 1 NC_002942.5 tRNA-(ms(2)io(6)a)-hydrolase(tRNA hydroxylase) 1714589 3077839 lpg1550 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA-(ms(2)io(6)a)-hydrolase(tRNA hydroxylase) YP_095579.1 1713954 D 272624 CDS YP_095580.1 52841781 3077848 complement(1714678..1715424) 1 NC_002942.5 hypothetical protein 1715424 3077848 lpg1551 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095580.1 1714678 R 272624 CDS YP_095581.1 52841782 3077828 complement(1715421..1716149) 1 NC_002942.5 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1716149 3077828 lpg1552 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-2,3-diacylglucosamine hydrolase YP_095581.1 1715421 R 272624 CDS YP_095582.1 52841783 3077852 complement(1716146..1716856) 1 NC_002942.5 septum site determining protein MinC 1716856 minC 3077852 minC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 septum site determining protein MinC YP_095582.1 1716146 R 272624 CDS YP_095583.1 52841784 3077758 1716913..1718622 1 NC_002942.5 long chain fatty acid-CoA ligase 1718622 fadD-1 3077758 fadD-1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 long chain fatty acid-CoA ligase YP_095583.1 1716913 D 272624 CDS YP_095584.1 52841785 3077771 complement(1718670..1719407) 1 NC_002942.5 arginine ABC transporter substrate-binding protein 1719407 artJ 3077771 artJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine ABC transporter substrate-binding protein YP_095584.1 1718670 R 272624 CDS YP_095585.1 52841786 3077769 complement(1719561..1719968) 1 NC_002942.5 MutT/nudix family protein 1719968 3077769 lpg1556 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MutT/nudix family protein YP_095585.1 1719561 R 272624 CDS YP_095586.1 52841787 3077756 complement(1720057..1721379) 1 NC_002942.5 para-aminobenzoate synthase, component I 1721379 3077756 lpg1557 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 para-aminobenzoate synthase, component I YP_095586.1 1720057 R 272624 CDS YP_095587.1 52841788 3077854 1721538..1722632 1 NC_002942.5 pyruvate dehydrogenase E1 alpha subunit 1722632 3077854 lpg1558 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate dehydrogenase E1 alpha subunit YP_095587.1 1721538 D 272624 CDS YP_095588.1 52841789 3077986 1722625..1723599 1 NC_002942.5 pyruvate dehydrogenase E1 beta subunit 1723599 3077986 lpg1559 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate dehydrogenase E1 beta subunit YP_095588.1 1722625 D 272624 CDS YP_095589.1 52841790 3078148 1723602..1724714 1 NC_002942.5 branched-chain alpha-keto acid dehydrogenase subunit E2 1724714 3078148 lpg1560 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_095589.1 1723602 D 272624 CDS YP_095590.1 52841791 3078196 1724886..1727105 1 NC_002942.5 potassium efflux system KefA 1727105 3078196 lpg1561 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 potassium efflux system KefA YP_095590.1 1724886 D 272624 CDS YP_095591.1 52841792 3077833 1727278..1729422 1 NC_002942.5 mercuric reductase 1729422 merA1 3077833 merA1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mercuric reductase YP_095591.1 1727278 D 272624 CDS YP_095592.1 52841793 3077997 complement(1729478..1730197) 1 NC_002942.5 hypothetical protein 1730197 3077997 lpg1563 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095592.1 1729478 R 272624 CDS YP_095593.1 52841794 3077999 complement(1730285..1731028) 1 NC_002942.5 hypothetical protein 1731028 3077999 lpg1564 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095593.1 1730285 R 272624 CDS YP_095594.1 52841795 3078002 1731264..1732214 1 NC_002942.5 thiamine biosynthesis protein NMT-1 1732214 thi3 3078002 thi3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiamine biosynthesis protein NMT-1 YP_095594.1 1731264 D 272624 CDS YP_095595.1 52841796 3078001 1732217..1733287 1 NC_002942.5 thiamine biosynthesis oxidoreductase ThiO 1733287 3078001 lpg1566 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiamine biosynthesis oxidoreductase ThiO YP_095595.1 1732217 D 272624 CDS YP_095596.1 52841797 3077860 1733483..1734274 1 NC_002942.5 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 1734274 thiG 3077860 thiG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiazole synthase YP_095596.1 1733483 D 272624 CDS YP_095597.1 52841798 3077941 1734250..1735737 1 NC_002942.5 phosphomethylpyrimidine kinase ThiD/thiamin-phosphate pyrophosphorylase fused protein ThiE 1735737 thiDE 3077941 thiDE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphomethylpyrimidine kinase ThiD/thiamin-phosphate pyrophosphorylase fused protein ThiE YP_095597.1 1734250 D 272624 CDS YP_095598.1 52841799 3077989 1735718..1736857 1 NC_002942.5 sulfurylase ThiF 1736857 3077989 lpg1569 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfurylase ThiF YP_095598.1 1735718 D 272624 CDS YP_095599.1 52841800 3077861 complement(1736886..1737743) 1 NC_002942.5 3'-nucleotidase/nuclease 1737743 3077861 lpg1570 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3'-nucleotidase/nuclease YP_095599.1 1736886 R 272624 CDS YP_095600.1 52841801 3077992 complement(1737722..1738981) 1 NC_002942.5 TolB colicin import protein 1738981 tolB 3077992 tolB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TolB colicin import protein YP_095600.1 1737722 R 272624 CDS YP_095601.1 52841802 3077991 complement(1738987..1739985) 1 NC_002942.5 TolA colicin import membrane protein 1739985 tolA 3077991 tolA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TolA colicin import membrane protein YP_095601.1 1738987 R 272624 CDS YP_095602.1 52841803 3077994 complement(1739982..1740437) 1 NC_002942.5 biopolymer transport protein TolR 1740437 tolR 3077994 tolR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biopolymer transport protein TolR YP_095602.1 1739982 R 272624 CDS YP_095603.1 52841804 3077998 complement(1740446..1741135) 1 NC_002942.5 biopolymer transport protein TolQ 1741135 tolQ 3077998 tolQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biopolymer transport protein TolQ YP_095603.1 1740446 R 272624 CDS YP_095604.1 52841805 3078000 complement(1741148..1741543) 1 NC_002942.5 esterase 1741543 3078000 lpg1575 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 esterase YP_095604.1 1741148 R 272624 CDS YP_095605.1 52841806 3077995 complement(1741547..1742578) 1 NC_002942.5 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1742578 ruvB 3077995 ruvB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Holliday junction DNA helicase RuvB YP_095605.1 1741547 R 272624 CDS YP_095606.1 52841807 3077922 complement(1742704..1743267) 1 NC_002942.5 RNA polymerase sigma E factor RpoE 1743267 rpoE 3077922 rpoE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA polymerase sigma E factor RpoE YP_095606.1 1742704 R 272624 CDS YP_095607.1 52841808 3077933 complement(1743361..1743810) 1 NC_002942.5 hypothetical protein 1743810 3077933 lpg1578 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095607.1 1743361 R 272624 CDS YP_095608.1 52841809 3077947 1744048..1745106 1 NC_002942.5 glycine cleavage T protein 1745106 3077947 lpg1579 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycine cleavage T protein YP_095608.1 1744048 D 272624 CDS YP_095609.1 52841810 3077980 complement(1745137..1745685) 1 NC_002942.5 cytochrome b-561 transmembrane protein 1745685 3077980 lpg1580 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome b-561 transmembrane protein YP_095609.1 1745137 R 272624 CDS YP_095610.1 52841811 3077904 complement(1745706..1750583) 1 NC_002942.5 NAD-glutamate dehydrogenase 1750583 3077904 lpg1581 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD-glutamate dehydrogenase YP_095610.1 1745706 R 272624 CDS YP_095611.1 52841812 3077990 complement(1750635..1751075) 1 NC_002942.5 hypothetical protein 1751075 3077990 lpg1582 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095611.1 1750635 R 272624 CDS YP_095612.1 52841813 3077940 complement(1751110..1752498) 1 NC_002942.5 succinate semialdehyde dehydrogenase 1752498 3077940 lpg1583 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate semialdehyde dehydrogenase YP_095612.1 1751110 R 272624 CDS YP_095613.1 52841814 3077993 1752829..1753596 1 NC_002942.5 (CDP-alcohol) phosphatidyltransferase 1753596 3077993 lpg1584 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (CDP-alcohol) phosphatidyltransferase YP_095613.1 1752829 D 272624 CDS YP_095614.1 52841815 3077996 1753919..1754407 1 NC_002942.5 hypothetical protein 1754407 3077996 lpg1585 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095614.1 1753919 D 272624 CDS YP_095615.1 52841816 3077857 1754534..1754911 1 NC_002942.5 hypothetical protein 1754911 3077857 lpg1586 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095615.1 1754534 D 272624 CDS YP_095616.1 52841817 3077951 1754935..1755492 1 NC_002942.5 hypothetical protein 1755492 3077951 lpg1587 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095616.1 1754935 D 272624 CDS YP_095617.1 52841818 3077928 complement(1755600..1757618) 1 NC_002942.5 hypothetical protein 1757618 legC6 3077928 legC6 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095617.1 1755600 R 272624 CDS YP_095618.1 52841819 3077637 complement(1757827..1758276) 1 NC_002942.5 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1758276 rplI 3077637 rplI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L9 YP_095618.1 1757827 R 272624 CDS YP_095619.1 52841820 3077915 complement(1758289..1759236) 1 NC_002942.5 hypothetical protein 1759236 3077915 lpg1590 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095619.1 1758289 R 272624 CDS YP_095620.1 52841821 3077952 complement(1759202..1759429) 1 NC_002942.5 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1759429 rpsR 3077952 rpsR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S18 YP_095620.1 1759202 R 272624 CDS YP_095621.1 52841822 3077634 complement(1759443..1759781) 1 NC_002942.5 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1759781 rpsF 3077634 rpsF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S6 YP_095621.1 1759443 R 272624 CDS YP_095622.1 52841823 3077983 1760090..1760287 1 NC_002942.5 carbon storage regulator CsrA 1760287 3077983 lpg1593 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbon storage regulator CsrA YP_095622.1 1760090 D 272624 CDS YP_095623.1 52841824 3077639 1760298..1761188 1 NC_002942.5 hypothetical protein 1761188 3077639 lpg1594 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095623.1 1760298 D 272624 CDS YP_095624.1 52841825 3077640 complement(1761225..1761959) 1 NC_002942.5 hypothetical protein 1761959 3077640 lpg1595 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095624.1 1761225 R 272624 CDS YP_095625.1 52841826 3077972 complement(1762019..1764037) 1 NC_002942.5 enoyl CoA hydratase 1764037 yfcX 3077972 yfcX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enoyl CoA hydratase YP_095625.1 1762019 R 272624 CDS YP_095626.1 52841827 3077635 complement(1764030..1765349) 1 NC_002942.5 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1765349 3077635 lpg1597 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl-CoA acetyltransferase YP_095626.1 1764030 R 272624 CDS YP_095627.1 52841828 3077943 complement(1765512..1766573) 1 NC_002942.5 hypothetical protein 1766573 3077943 lpg1598 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095627.1 1765512 R 272624 CDS YP_095628.1 52841829 3077921 complement(1766723..1766929) 1 NC_002942.5 hypothetical protein 1766929 3077921 lpg1599 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095628.1 1766723 R 272624 CDS YP_095629.1 52841830 3077934 complement(1766981..1768267) 1 NC_002942.5 FLJ00180 protein; hypothetical protein 1768267 legL2 3077934 legL2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095629.1 1766981 R 272624 CDS YP_095630.1 52841831 3077976 1768731..1770155 1 NC_002942.5 phospholipase 1770155 3077976 lpg1603 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospholipase YP_095630.1 1768731 D 272624 CDS YP_095631.1 52841832 3077948 complement(1770226..1770903) 1 NC_002942.5 hypothetical protein 1770903 3077948 lpg1604 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095631.1 1770226 R 272624 CDS YP_095632.1 52841833 3077956 complement(1770905..1771384) 1 NC_002942.5 hypothetical protein 1771384 3077956 lpg1605 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095632.1 1770905 R 272624 CDS YP_095633.1 52841834 3077978 1771492..1772151 1 NC_002942.5 hypothetical protein 1772151 3077978 lpg1606 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095633.1 1771492 D 272624 CDS YP_095634.1 52841835 3077945 1772377..1774704 1 NC_002942.5 phosphoenolpyruvate carboxylase 1774704 capP 3077945 capP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoenolpyruvate carboxylase YP_095634.1 1772377 D 272624 CDS YP_095635.1 52841836 3077925 1774858..1775340 1 NC_002942.5 MutT/nudix family protein 1775340 3077925 lpg1608 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MutT/nudix family protein YP_095635.1 1774858 D 272624 CDS YP_095636.1 52841837 3077638 complement(1775391..1776644) 1 NC_002942.5 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1776644 proA 3077638 proA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 gamma-glutamyl phosphate reductase YP_095636.1 1775391 R 272624 CDS YP_095637.1 52841838 3077970 complement(1776653..1777723) 1 NC_002942.5 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1777723 proB 3077970 proB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 gamma-glutamyl kinase YP_095637.1 1776653 R 272624 CDS YP_095638.1 52841839 3077973 complement(1778154..1779101) 1 NC_002942.5 MerR family transcriptional regulator 1779101 3077973 lpg1611 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MerR family transcriptional regulator YP_095638.1 1778154 R 272624 CDS YP_095639.1 52841840 3077939 complement(1779352..1780104) 1 NC_002942.5 transcriptional regulator SkgA 1780104 3077939 lpg1612 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator SkgA YP_095639.1 1779352 R 272624 CDS YP_095640.1 52841841 3077977 complement(1780170..1780697) 1 NC_002942.5 acetyltransferase 1780697 3077977 lpg1613 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_095640.1 1780170 R 272624 CDS YP_095641.1 52841842 3077981 complement(1780694..1781650) 1 NC_002942.5 hypothetical protein 1781650 yqkA 3077981 yqkA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095641.1 1780694 R 272624 CDS YP_095642.1 52841843 3077906 complement(1781654..1783435) 1 NC_002942.5 hypothetical protein 1783435 abcT3 3077906 abcT3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095642.1 1781654 R 272624 CDS YP_095643.1 52841844 3077908 complement(1783428..1784888) 1 NC_002942.5 erythromycin ABC transporter ATP-binding protein 1784888 uup 3077908 uup Legionella pneumophila subsp. pneumophila str. Philadelphia 1 erythromycin ABC transporter ATP-binding protein YP_095643.1 1783428 R 272624 CDS YP_095644.1 52841845 3077955 1785236..1786108 1 NC_002942.5 hypothetical protein 1786108 3077955 lpg1617 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095644.1 1785236 D 272624 CDS YP_095645.1 52841846 3077937 complement(1786233..1787075) 1 NC_002942.5 beta-lactamase AmpS 1787075 3077937 lpg1618 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 beta-lactamase AmpS YP_095645.1 1786233 R 272624 CDS YP_095646.1 52841847 3077929 complement(1787083..1788993) 1 NC_002942.5 cell division protein FtsI 1788993 ftsI4 3077929 ftsI4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein FtsI YP_095646.1 1787083 R 272624 CDS YP_095647.1 52841848 3077963 complement(1788993..1789433) 1 NC_002942.5 hypothetical protein 1789433 3077963 lpg1620 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095647.1 1788993 R 272624 CDS YP_095648.1 52841849 3077917 complement(1789603..1790922) 1 NC_002942.5 hypothetical protein 1790922 3077917 lpg1621 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095648.1 1789603 R 272624 CDS YP_095649.1 52841850 3077862 complement(1791042..1791815) 1 NC_002942.5 hypothetical protein 1791815 3077862 lpg1622 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095649.1 1791042 R 272624 CDS YP_095650.1 52841851 3077645 complement(1791933..1792964) 1 NC_002942.5 hydrogenase 1792964 3077645 lpg1623 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase YP_095650.1 1791933 R 272624 CDS YP_095651.1 52841852 3077902 1793220..1794203 1 NC_002942.5 alpha/beta hydrolase 1794203 3077902 lpg1624 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha/beta hydrolase YP_095651.1 1793220 D 272624 CDS YP_095652.1 52841853 3077872 complement(1794227..1794619) 1 NC_002942.5 hypothetical protein 1794619 3077872 lpg1625 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095652.1 1794227 R 272624 CDS YP_095653.1 52841854 3077923 complement(1794864..1797071) 1 NC_002942.5 copper efflux ATPase 1797071 3077923 lpg1626 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 copper efflux ATPase YP_095653.1 1794864 R 272624 CDS YP_095654.1 52841855 3077651 1797226..1798140 1 NC_002942.5 secreted protein 1798140 3077651 lpg1627 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 secreted protein YP_095654.1 1797226 D 272624 CDS YP_095655.1 52841856 3077871 complement(1798234..1799544) 1 NC_002942.5 coenzyme F390 synthetase FtsA 1799544 3077871 lpg1628 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coenzyme F390 synthetase FtsA YP_095655.1 1798234 R 272624 CDS YP_095656.1 52841857 3077914 complement(1799502..1800338) 1 NC_002942.5 Zn-dependent hydrolase GumP 1800338 3077914 lpg1629 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Zn-dependent hydrolase GumP YP_095656.1 1799502 R 272624 CDS YP_095657.1 52841858 3077873 complement(1800317..1801303) 1 NC_002942.5 3-beta-hydroxysteroid dehydrogenase/isomerase 1801303 3077873 lpg1630 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-beta-hydroxysteroid dehydrogenase/isomerase YP_095657.1 1800317 R 272624 CDS YP_095658.1 52841859 3077867 complement(1801305..1802288) 1 NC_002942.5 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1802288 3077867 lpg1631 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_095658.1 1801305 R 272624 CDS YP_095659.1 52841860 3077967 1802420..1803601 1 NC_002942.5 glycosyltransferase 1803601 3077967 lpg1632 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyltransferase YP_095659.1 1802420 D 272624 CDS YP_095660.1 52841861 3077969 1803601..1804257 1 NC_002942.5 hypothetical protein 1804257 3077969 lpg1633 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095660.1 1803601 D 272624 CDS YP_095661.1 52841862 3077909 complement(1804345..1807347) 1 NC_002942.5 oxidase 1807347 3077909 lpg1634 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidase YP_095661.1 1804345 R 272624 CDS YP_095662.1 52841863 3077985 1807502..1808041 1 NC_002942.5 dienelactone hydrolase 1808041 3077985 lpg1635 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dienelactone hydrolase YP_095662.1 1807502 D 272624 CDS YP_095663.1 52841864 3077896 1808095..1808943 1 NC_002942.5 acetyltransferase 1808943 3077896 lpg1636 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_095663.1 1808095 D 272624 CDS YP_095664.1 52841865 3077886 1808947..1809837 1 NC_002942.5 polysaccharide deacetylase 1809837 3077886 lpg1637 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polysaccharide deacetylase YP_095664.1 1808947 D 272624 CDS YP_095665.1 52841866 3077649 1809954..1811267 1 NC_002942.5 drug:proton antiporter 1811267 3077649 lpg1638 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 drug:proton antiporter YP_095665.1 1809954 D 272624 CDS YP_095666.1 52841867 3077877 complement(1811280..1812596) 1 NC_002942.5 hypothetical protein 1812596 3077877 lpg1639 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095666.1 1811280 R 272624 CDS YP_095667.1 52841868 3077889 1812687..1813244 1 NC_002942.5 transmembrane protein 1813244 3077889 lpg1640 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095667.1 1812687 D 272624 CDS YP_095668.1 52841869 3077870 complement(1813262..1815241) 1 NC_002942.5 acylaminoacyl peptidase 1815241 3077870 lpg1641 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acylaminoacyl peptidase YP_095668.1 1813262 R 272624 CDS YP_095669.1 52841870 3077664 complement(1815442..1816695) 1 NC_002942.5 conserved gene, Rtx-like; protein SidB 1816695 sidB 3077664 sidB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidB YP_095669.1 1815442 R 272624 CDS YP_095670.2 161723252 3077672 complement(1816951..1818219) 1 NC_002942.5 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1818219 thrC 3077672 thrC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 threonine synthase YP_095670.2 1816951 R 272624 CDS YP_095671.1 52841872 3077693 complement(1818391..1819155) 1 NC_002942.5 hypothetical protein 1819155 3077693 lpg1644 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095671.1 1818391 R 272624 CDS YP_095672.1 52841873 3077708 complement(1819383..1819958) 1 NC_002942.5 hypothetical protein 1819958 3077708 lpg1645 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095672.1 1819383 R 272624 CDS YP_095673.1 52841874 3077783 complement(1819958..1820488) 1 NC_002942.5 cytochrome b561 transmembrane protein 1820488 3077783 lpg1646 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome b561 transmembrane protein YP_095673.1 1819958 R 272624 CDS YP_095674.1 52841875 3077647 complement(1820492..1821091) 1 NC_002942.5 hypothetical protein 1821091 3077647 lpg1647 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095674.1 1820492 R 272624 CDS YP_095675.1 52841876 3077893 complement(1821113..1821370) 1 NC_002942.5 signal peptide protein 1821370 3077893 lpg1648 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide protein YP_095675.1 1821113 R 272624 CDS YP_095676.1 52841877 3077868 complement(1821492..1822394) 1 NC_002942.5 myo-inositol catabolism protein IolE 1822394 iolE 3077868 iolE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 myo-inositol catabolism protein IolE YP_095676.1 1821492 R 272624 CDS YP_095677.1 52841878 3077882 complement(1822391..1824262) 1 NC_002942.5 myo-inositol catabolism protein IolD 1824262 iolD 3077882 iolD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 myo-inositol catabolism protein IolD YP_095677.1 1822391 R 272624 CDS YP_095678.1 52841879 3077883 complement(1824301..1826187) 1 NC_002942.5 IolC/IolB transferase kinase 1826187 3077883 lpg1651 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IolC/IolB transferase kinase YP_095678.1 1824301 R 272624 CDS YP_095679.1 52841880 3077876 complement(1826195..1827199) 1 NC_002942.5 myo-inositol-2-dehydrogenase 1827199 3077876 lpg1652 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 myo-inositol-2-dehydrogenase YP_095679.1 1826195 R 272624 CDS YP_095680.1 52841881 3077782 complement(1827202..1828617) 1 NC_002942.5 D-xylose-proton symporter 1828617 3077782 lpg1653 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-xylose-proton symporter YP_095680.1 1827202 R 272624 CDS YP_095681.1 52841882 3077806 complement(1829032..1830150) 1 NC_002942.5 hypothetical protein 1830150 3077806 lpg1654 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095681.1 1829032 R 272624 CDS YP_095682.1 52841883 3077652 complement(1830346..1832019) 1 NC_002942.5 class 4 metalloprotease 1832019 lasB 3077652 lasB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 class 4 metalloprotease YP_095682.1 1830346 R 272624 CDS YP_095683.1 52841884 3077801 complement(1832061..1833014) 1 NC_002942.5 hypothetical protein 1833014 3077801 lpg1656 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095683.1 1832061 R 272624 CDS YP_095684.1 52841885 3077795 1833166..1833933 1 NC_002942.5 NG,NG-dimethylarginine dimethylaminohydrolase 1833933 3077795 lpg1657 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NG,NG-dimethylarginine dimethylaminohydrolase YP_095684.1 1833166 D 272624 CDS YP_095685.1 52841886 3077780 1833912..1835249 1 NC_002942.5 amino acid antiporter 1835249 3077780 lpg1658 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid antiporter YP_095685.1 1833912 D 272624 CDS YP_095686.1 52841887 3077799 1835379..1836422 1 NC_002942.5 hypothetical protein 1836422 3077799 lpg1659 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095686.1 1835379 D 272624 CDS YP_095687.1 52841888 3077864 1836560..1838041 1 NC_002942.5 hypothetical protein 1838041 legL3 3077864 legL3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095687.1 1836560 D 272624 CDS YP_095688.1 52841889 3077811 complement(1838135..1839253) 1 NC_002942.5 hypothetical protein 1839253 3077811 lpg1661 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095688.1 1838135 R 272624 CDS YP_095689.1 52841890 3078003 1839414..1840010 1 NC_002942.5 transporter 1840010 3078003 lpg1662 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter YP_095689.1 1839414 D 272624 CDS YP_095690.1 52841891 3078013 1840168..1840674 1 NC_002942.5 hypothetical protein 1840674 3078013 lpg1663 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095690.1 1840168 D 272624 CDS YP_095691.1 52841892 3077643 complement(1840733..1843051) 1 NC_002942.5 penicillin binding protein 1C, peptidoglycan biosynthesis 1843051 3077643 lpg1664 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 penicillin binding protein 1C, peptidoglycan biosynthesis YP_095691.1 1840733 R 272624 CDS YP_095692.1 52841893 3077879 1843217..1848982 1 NC_002942.5 hypothetical protein 1848982 3077879 lpg1665 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095692.1 1843217 D 272624 CDS YP_095693.1 52841894 3077918 complement(1849247..1850650) 1 NC_002942.5 hypothetical protein 1850650 3077918 lpg1666 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095693.1 1849247 R 272624 CDS YP_095694.1 52841895 3077903 complement(1850812..1852203) 1 NC_002942.5 hypothetical protein 1852203 3077903 lpg1667 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095694.1 1850812 R 272624 CDS YP_095695.1 52841896 3077817 complement(1852351..1853235) 1 NC_002942.5 hypothetical protein 1853235 3077817 lpg1668 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095695.1 1852351 R 272624 CDS YP_095696.1 52841897 3077785 complement(1854141..1856366) 1 NC_002942.5 alpha-amylase 1856366 3077785 lpg1669 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha-amylase YP_095696.1 1854141 R 272624 CDS YP_095697.1 52841898 3077784 1856669..1857559 1 NC_002942.5 hypothetical protein 1857559 3077784 lpg1670 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095697.1 1856669 D 272624 CDS YP_095698.1 52841899 3078016 1857651..1859780 1 NC_002942.5 alpha-amylase 1859780 3078016 lpg1671 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha-amylase YP_095698.1 1857651 D 272624 CDS YP_095699.1 52841900 3077657 complement(1859777..1860355) 1 NC_002942.5 phosphoribosylglycinamide formyltransferase 1860355 3077657 lpg1672 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylglycinamide formyltransferase YP_095699.1 1859777 R 272624 CDS YP_095700.1 52841901 3077890 complement(1860352..1861671) 1 NC_002942.5 phosphoribosylamine-glycine ligase 1861671 3077890 lpg1673 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylamine-glycine ligase YP_095700.1 1860352 R 272624 CDS YP_095701.1 52841902 3077809 complement(1861668..1863167) 1 NC_002942.5 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1863167 purF 3077809 purF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amidophosphoribosyltransferase YP_095701.1 1861668 R 272624 CDS YP_095702.1 52841903 3077712 complement(1863190..1864185) 1 NC_002942.5 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1864185 3077712 lpg1675 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_095702.1 1863190 R 272624 CDS YP_095703.1 52841904 3078010 complement(1864151..1865413) 1 NC_002942.5 phosphoribosylformylglycinamidine synthase I 1865413 purQ 3078010 purQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylformylglycinamidine synthase I YP_095703.1 1864151 R 272624 CDS YP_095704.1 52841905 3077698 complement(1865410..1866486) 1 NC_002942.5 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1866486 purM 3077698 purM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylaminoimidazole synthetase YP_095704.1 1865410 R 272624 CDS YP_095705.1 52841906 3077736 complement(1866453..1868795) 1 NC_002942.5 phosphoribosylformylglycinamidine synthase II 1868795 purL2 3077736 purL2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoribosylformylglycinamidine synthase II YP_095705.1 1866453 R 272624 CDS YP_095706.1 52841907 3077725 complement(1868948..1869661) 1 NC_002942.5 hypothetical protein 1869661 3077725 lpg1679 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095706.1 1868948 R 272624 CDS YP_095707.1 52841908 3077802 complement(1870228..1871607) 1 NC_002942.5 thiol:disulfide interchange protein DsbD 1871607 dsbD 3077802 dsbD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiol:disulfide interchange protein DsbD YP_095707.1 1870228 R 272624 CDS YP_095708.1 52841909 3077794 complement(1871705..1872022) 1 NC_002942.5 hypothetical protein 1872022 3077794 lpg1681 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095708.1 1871705 R 272624 CDS YP_095709.1 52841910 3077822 complement(1872119..1872970) 1 NC_002942.5 short chain dehydrogenase/reductase oxidoreductase 1872970 3077822 lpg1682 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase/reductase oxidoreductase YP_095709.1 1872119 R 272624 CDS YP_095710.1 52841911 3077714 1873124..1874632 1 NC_002942.5 hypothetical protein 1874632 3077714 lpg1683 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095710.1 1873124 D 272624 CDS YP_095711.1 52841912 3077727 1874936..1876333 1 NC_002942.5 hypothetical protein 1876333 3077727 lpg1684 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095711.1 1874936 D 272624 CDS YP_095712.1 52841913 3078011 complement(1876344..1877213) 1 NC_002942.5 hypothetical protein 1877213 3078011 lpg1685 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095712.1 1876344 R 272624 CDS YP_095713.1 52841914 3077683 1877432..1877749 1 NC_002942.5 hypothetical protein 1877749 3077683 lpg1686 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095713.1 1877432 D 272624 CDS YP_095714.1 52841915 3077685 complement(1877800..1879002) 1 NC_002942.5 hypothetical protein 1879002 3077685 lpg1687 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095714.1 1877800 R 272624 CDS YP_095715.1 52841916 3077707 complement(1879039..1880283) 1 NC_002942.5 flagellar hook-length control protein 1880283 3077707 lpg1688 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook-length control protein YP_095715.1 1879039 R 272624 CDS YP_095716.1 52841917 3078067 1880467..1881093 1 NC_002942.5 hypothetical protein 1881093 3078067 lpg1689 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095716.1 1880467 D 272624 CDS YP_095717.1 52841918 3078080 1881178..1883853 1 NC_002942.5 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1883853 acnA 3078080 acnA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aconitate hydratase YP_095717.1 1881178 D 272624 CDS YP_095718.1 52841919 3078095 1884118..1885512 1 NC_002942.5 amino acid antiporter 1885512 3078095 lpg1691 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid antiporter YP_095718.1 1884118 D 272624 CDS YP_095719.1 52841920 3077787 1885806..1887116 1 NC_002942.5 hypothetical protein 1887116 3077787 lpg1692 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095719.1 1885806 D 272624 CDS YP_095720.1 52841921 3077942 complement(1887061..1887339) 1 NC_002942.5 hypothetical protein 1887339 3077942 lpg1693 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095720.1 1887061 R 272624 CDS YP_095721.1 52841922 3077884 complement(1887472..1887846) 1 NC_002942.5 transposase IS630 family 1887846 3077884 lpg1694 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase IS630 family YP_095721.1 1887472 R 272624 CDS YP_095722.1 52841923 3077912 complement(1887731..1888036) 1 NC_002942.5 transposase IS630 family 1888036 3077912 lpg1695 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase IS630 family YP_095722.1 1887731 R 272624 CDS YP_095723.1 52841924 3078033 complement(1888202..1891366) 1 NC_002942.5 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1891366 putA 3078033 putA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_095723.1 1888202 R 272624 CDS YP_095724.1 52841925 3077679 1891911..1892588 1 NC_002942.5 hypothetical protein 1892588 3077679 lpg1697 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095724.1 1891911 D 272624 CDS YP_095725.1 52841926 3078089 1893014..1893385 1 NC_002942.5 ProQ-like, activator of ProP osmoprotectant transporter 1893385 3078089 lpg1698 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ProQ-like, activator of ProP osmoprotectant transporter YP_095725.1 1893014 D 272624 CDS YP_095726.1 52841927 3078005 complement(1893413..1894105) 1 NC_002942.5 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1894105 ubiG 3078005 ubiG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-demethylubiquinone-9 3-methyltransferase YP_095726.1 1893413 R 272624 CDS YP_095727.1 52841928 3078076 complement(1894092..1894811) 1 NC_002942.5 uracil DNA glycosylase 1894811 3078076 lpg1700 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uracil DNA glycosylase YP_095727.1 1894092 R 272624 CDS YP_095728.1 52841929 3078088 1895076..1896758 1 NC_002942.5 coiled-coil-containing protein; kinectin 1 1896758 legC3 3078088 legC3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 kinectin 1 YP_095728.1 1895076 D 272624 CDS YP_095729.1 52841930 3078038 1896894..1898534 1 NC_002942.5 hypothetical protein 1898534 3078038 lpg1702 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095729.1 1896894 D 272624 CDS YP_095730.1 52841931 3077665 complement(1898621..1899916) 1 NC_002942.5 SOS mutagenesis and repair UmuC protein 1899916 3077665 lpg1703 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SOS mutagenesis and repair UmuC protein YP_095730.1 1898621 R 272624 CDS YP_095731.1 52841932 3078035 complement(1899877..1900431) 1 NC_002942.5 SOS (error prone) mutagenesis protein UmuD (RumA) 1900431 3078035 lpg1704 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SOS (error prone) mutagenesis protein UmuD (RumA) YP_095731.1 1899877 R 272624 CDS YP_095732.1 52841933 3077808 1900567..1901790 1 NC_002942.5 hypothetical protein 1901790 3077808 lpg1705 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095732.1 1900567 D 272624 CDS YP_095733.1 52841934 3078055 1901787..1902830 1 NC_002942.5 arginine N-succinyltransferase subunit beta 1902830 3078055 lpg1706 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginine N-succinyltransferase subunit beta YP_095733.1 1901787 D 272624 CDS YP_095734.1 52841935 3077778 1902841..1904331 1 NC_002942.5 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1904331 astD 3077778 astD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinylglutamic semialdehyde dehydrogenase YP_095734.1 1902841 D 272624 CDS YP_095735.1 52841936 3078040 1904337..1905683 1 NC_002942.5 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1905683 astB 3078040 astB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinylarginine dihydrolase YP_095735.1 1904337 D 272624 CDS YP_095736.1 52841937 3078039 1905680..1906420 1 NC_002942.5 hypothetical protein 1906420 3078039 lpg1709 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095736.1 1905680 D 272624 CDS YP_095737.1 52841938 3077673 complement(1906498..1906863) 1 NC_002942.5 hypothetical protein 1906863 3077673 lpg1710 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095737.1 1906498 R 272624 CDS YP_095738.1 52841939 3078050 complement(1907241..1907798) 1 NC_002942.5 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1907798 frr 3078050 frr Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosome recycling factor YP_095738.1 1907241 R 272624 CDS YP_095739.1 52841940 3077684 complement(1907788..1908531) 1 NC_002942.5 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1908531 pyrH 3077684 pyrH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uridylate kinase YP_095739.1 1907788 R 272624 CDS YP_095740.2 161723251 3078014 complement(1908528..1909406) 1 NC_002942.5 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1909406 tsf 3078014 tsf Legionella pneumophila subsp. pneumophila str. Philadelphia 1 elongation factor Ts YP_095740.2 1908528 R 272624 CDS YP_095741.2 161723250 3077728 complement(1909472..1910236) 1 NC_002942.5 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1910236 rpsB 3077728 rpsB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S2 YP_095741.2 1909472 R 272624 CDS YP_095742.1 52841943 3078068 1910570..1910980 1 NC_002942.5 hypothetical protein 1910980 3078068 lpg1715 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095742.1 1910570 D 272624 CDS YP_095743.1 52841944 3077667 1911490..1911948 1 NC_002942.5 hypothetical protein 1911948 3077667 lpg1716 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095743.1 1911490 D 272624 CDS YP_095744.1 52841945 3078071 complement(1912012..1913700) 1 NC_002942.5 hypothetical protein 1913700 3078071 lpg1717 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095744.1 1912012 R 272624 CDS YP_095745.1 52841946 3078060 complement(1914091..1915728) 1 NC_002942.5 conserved gene, HYP-B; contains ankyrin repeats and SET; hypothetical protein 1915728 legAS4 3078060 legAS4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095745.1 1914091 R 272624 CDS YP_095746.1 52841947 3077724 1915872..1916636 1 NC_002942.5 methionine aminopeptidase 1916636 map 3077724 map Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionine aminopeptidase YP_095746.1 1915872 D 272624 CDS YP_095747.1 52841948 3078047 1916623..1919208 1 NC_002942.5 protein-PII uridylyltransferase 1919208 glnD 3078047 glnD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein-PII uridylyltransferase YP_095747.1 1916623 D 272624 CDS YP_095748.1 52841949 3077735 complement(1919230..1919655) 1 NC_002942.5 deaminase 1919655 yfhC 3077735 yfhC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deaminase YP_095748.1 1919230 R 272624 CDS YP_095749.1 52841950 3077713 complement(1919670..1921247) 1 NC_002942.5 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1921247 guaA 3077713 guaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GMP synthase YP_095749.1 1919670 R 272624 CDS YP_095750.1 52841951 3077815 complement(1921250..1922722) 1 NC_002942.5 inosine-5'-monophosphate dehydrogenase 1922722 guaB 3077815 guaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inosine-5'-monophosphate dehydrogenase YP_095750.1 1921250 R 272624 CDS YP_095751.1 52841952 3077703 1922931..1923761 1 NC_002942.5 septum site-determining protein MinD 1923761 minD 3077703 minD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 septum site-determining protein MinD YP_095751.1 1922931 D 272624 CDS YP_095752.1 52841953 3078122 complement(1924342..1926828) 1 NC_002942.5 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 1926828 fadE 3078122 fadE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl-CoA dehydrogenase YP_095752.1 1924342 R 272624 CDS YP_095753.1 52841954 3078126 complement(1926921..1927706) 1 NC_002942.5 hydrolase 1927706 3078126 lpg1727 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrolase YP_095753.1 1926921 R 272624 CDS YP_095754.1 52841955 3078146 complement(1927703..1928620) 1 NC_002942.5 hypothetical protein 1928620 3078146 lpg1728 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095754.1 1927703 R 272624 CDS YP_095755.1 52841956 3078150 complement(1928571..1929662) 1 NC_002942.5 sn-glycerol-3-phosphate transport, ATP-binding protein 1929662 ugpC 3078150 ugpC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sn-glycerol-3-phosphate transport, ATP-binding protein YP_095755.1 1928571 R 272624 CDS YP_095756.1 52841957 3078153 complement(1929662..1930432) 1 NC_002942.5 sn-glycerol-3-phosphate transmembrane ABC transporter 1930432 ugpE 3078153 ugpE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sn-glycerol-3-phosphate transmembrane ABC transporter YP_095756.1 1929662 R 272624 CDS YP_095757.1 52841958 3078156 complement(1930486..1931364) 1 NC_002942.5 sn-glycerol-3-phosphate transmembrane ABC transporter 1931364 ugpA 3078156 ugpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sn-glycerol-3-phosphate transmembrane ABC transporter YP_095757.1 1930486 R 272624 CDS YP_095758.1 52841959 3078162 1931484..1932485 1 NC_002942.5 quinone oxidoreductase 1932485 qor 3078162 qor Legionella pneumophila subsp. pneumophila str. Philadelphia 1 quinone oxidoreductase YP_095758.1 1931484 D 272624 CDS YP_095759.1 52841960 3078165 complement(1932659..1933942) 1 NC_002942.5 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 1933942 3078165 lpg1733 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chloride channel protein YP_095759.1 1932659 R 272624 CDS YP_095760.1 52841961 3078066 complement(1933935..1936091) 1 NC_002942.5 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase 1936091 3078066 lpg1734 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 anthranilate synthase YP_095760.1 1933935 R 272624 CDS YP_095761.1 52841962 3078171 1936350..1936652 1 NC_002942.5 glutamyl/tRNA (Gln) amidotransferase subunit C 1936652 gatC 3078171 gatC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamyl/tRNA (Gln) amidotransferase subunit C YP_095761.1 1936350 D 272624 CDS YP_095762.1 52841963 3078173 1936655..1938106 1 NC_002942.5 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1938106 gatA 3078173 gatA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_095762.1 1936655 D 272624 CDS YP_095763.1 52841964 3078177 1938110..1939543 1 NC_002942.5 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1939543 gatB 3078177 gatB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_095763.1 1938110 D 272624 CDS YP_095764.1 52841965 3078183 1939747..1940736 1 NC_002942.5 hypothetical protein 1940736 3078183 lpg1738 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095764.1 1939747 D 272624 CDS YP_095765.1 52841966 3078192 1940874..1943180 1 NC_002942.5 hypothetical protein 1943180 gidA 3078192 gidA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095765.1 1940874 D 272624 CDS YP_095766.1 52841967 3078205 1943220..1943684 1 NC_002942.5 hypothetical protein 1943684 3078205 lpg1740 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095766.1 1943220 D 272624 CDS YP_095767.1 52841968 3078209 1943704..1944492 1 NC_002942.5 hypothetical protein 1944492 3078209 lpg1741 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095767.1 1943704 D 272624 CDS YP_095768.1 52841969 3078222 1944499..1944945 1 NC_002942.5 hypothetical protein 1944945 3078222 lpg1742 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095768.1 1944499 D 272624 CDS YP_095769.1 52841970 3078227 complement(1945064..1945351) 1 NC_002942.5 Fis family transcriptional regulator 1945351 fis 3078227 fis Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Fis family transcriptional regulator YP_095769.1 1945064 R 272624 CDS YP_095770.1 52841971 3078257 complement(1945747..1946115) 1 NC_002942.5 HesB family protein 1946115 ydiC 3078257 ydiC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HesB family protein YP_095770.1 1945747 R 272624 CDS YP_095771.1 52841972 3078260 complement(1946120..1946503) 1 NC_002942.5 NifU family iron binding protein [Fe-S] cluster formation/repair protein IscU, HesB 1946503 3078260 lpg1745 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NifU family iron binding protein [Fe-S] cluster formation/repair protein IscU, HesB YP_095771.1 1946120 R 272624 CDS YP_095772.1 52841973 3078276 complement(1946500..1947663) 1 NC_002942.5 cysteine desulfurase 1947663 iscS 3078276 iscS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cysteine desulfurase YP_095772.1 1946500 R 272624 CDS YP_095773.1 52841974 3077792 complement(1947638..1948411) 1 NC_002942.5 RNA methyltransferase 1948411 3077792 lpg1747 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA methyltransferase YP_095773.1 1947638 R 272624 CDS YP_095774.1 52841975 3078289 1948527..1949312 1 NC_002942.5 inositol monophosphatase 1949312 suhB 3078289 suhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inositol monophosphatase YP_095774.1 1948527 D 272624 CDS YP_095775.1 52841976 3078307 complement(1949425..1950381) 1 NC_002942.5 signal peptide peptidase 1950381 sppA 3078307 sppA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide peptidase YP_095775.1 1949425 R 272624 CDS YP_095776.1 52841977 3077814 1950470..1953046 1 NC_002942.5 endopeptidase Clp ATP-binding chain B (ClpB) 1953046 clpB 3077814 clpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endopeptidase Clp ATP-binding chain B (ClpB) YP_095776.1 1950470 D 272624 CDS YP_095777.1 52841978 3078315 complement(1953138..1954448) 1 NC_002942.5 hypothetical protein 1954448 3078315 lpg1751 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095777.1 1953138 R 272624 CDS YP_095778.1 52841979 3078326 complement(1954461..1955108) 1 NC_002942.5 hypothetical protein 1955108 3078326 lpg1752 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095778.1 1954461 R 272624 CDS YP_095779.1 52841980 3078356 complement(1955401..1956768) 1 NC_002942.5 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1956768 mpl 3078356 mpl Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_095779.1 1955401 R 272624 CDS YP_095780.1 52841981 3078364 complement(1956770..1957390) 1 NC_002942.5 hypothetical protein 1957390 3078364 lpg1754 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095780.1 1956770 R 272624 CDS YP_095781.1 52841982 3078367 complement(1957443..1961264) 1 NC_002942.5 transmembrane protein 1961264 3078367 lpg1755 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095781.1 1957443 R 272624 CDS YP_095782.1 52841983 3078379 complement(1961254..1961709) 1 NC_002942.5 flagellar protein FliJ 1961709 fliJ 3078379 fliJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar protein FliJ YP_095782.1 1961254 R 272624 CDS YP_095783.1 52841984 3078409 complement(1961706..1963058) 1 NC_002942.5 flagellum-specific ATP synthase FliI 1963058 fliI 3078409 fliI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellum-specific ATP synthase FliI YP_095783.1 1961706 R 272624 CDS YP_095784.1 52841985 3078418 complement(1963058..1963696) 1 NC_002942.5 flagellar assembly protein FliH 1963696 fliH 3078418 fliH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar assembly protein FliH YP_095784.1 1963058 R 272624 CDS YP_095785.1 52841986 3077781 complement(1963838..1964827) 1 NC_002942.5 flagellar motor switch protein FliG 1964827 fliG 3077781 fliG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor switch protein FliG YP_095785.1 1963838 R 272624 CDS YP_095786.1 52841987 3077803 complement(1964830..1966464) 1 NC_002942.5 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1966464 fliF 3077803 fliF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar MS-ring protein YP_095786.1 1964830 R 272624 CDS YP_095787.1 52841988 3077786 complement(1966636..1966950) 1 NC_002942.5 flagellar hook-basal body protein FliE 1966950 3077786 lpg1761 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar hook-basal body protein FliE YP_095787.1 1966636 R 272624 CDS YP_095788.1 52841989 3078170 complement(1966965..1968326) 1 NC_002942.5 sigma 54-dependent response regulator 1968326 fleR 3078170 fleR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sigma 54-dependent response regulator YP_095788.1 1966965 R 272624 CDS YP_095789.1 52841990 3078235 complement(1968302..1969333) 1 NC_002942.5 sensor kinase HydH 1969333 flrB 3078235 flrB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor kinase HydH YP_095789.1 1968302 R 272624 CDS YP_095790.1 52841991 3078398 complement(1969632..1970936) 1 NC_002942.5 recombination factor protein RarA 1970936 3078398 lpg1764 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 recombination factor protein RarA YP_095790.1 1969632 R 272624 CDS YP_095791.1 52841992 3078042 complement(1970952..1971566) 1 NC_002942.5 outer membrane lipoprotein carrier protein 1971566 lolA 3078042 lolA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane lipoprotein carrier protein YP_095791.1 1970952 R 272624 CDS YP_095792.1 52841993 3078286 complement(1971563..1973947) 1 NC_002942.5 DNA translocase FtsK 1973947 ftsK 3078286 ftsK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA translocase FtsK YP_095792.1 1971563 R 272624 CDS YP_095793.1 52841994 3078309 1973921..1974970 1 NC_002942.5 thioredoxin reductase 1974970 trxB1 3078309 trxB1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thioredoxin reductase YP_095793.1 1973921 D 272624 CDS YP_095794.1 52841995 3078200 1974973..1975641 1 NC_002942.5 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1975641 aat 3078200 aat Legionella pneumophila subsp. pneumophila str. Philadelphia 1 leucyl/phenylalanyl-tRNA--protein transferase YP_095794.1 1974973 D 272624 CDS YP_095795.1 52841996 3078382 1975696..1976067 1 NC_002942.5 rhodanese domain-containing protein 1976067 3078382 lpg1769 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rhodanese domain-containing protein YP_095795.1 1975696 D 272624 CDS YP_095796.1 52841997 3078352 1976198..1976419 1 NC_002942.5 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1976419 infA 3078352 infA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 translation initiation factor IF-1 YP_095796.1 1976198 D 272624 CDS YP_095797.1 52841998 3078051 complement(1976586..1978001) 1 NC_002942.5 peptide maturation protein PmbA 1978001 pmbA 3078051 pmbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide maturation protein PmbA YP_095797.1 1976586 R 272624 CDS YP_095798.1 52841999 3078101 1977990..1978766 1 NC_002942.5 hypothetical protein 1978766 3078101 lpg1772 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095798.1 1977990 D 272624 CDS YP_095799.1 52842000 3078281 1979015..1979965 1 NC_002942.5 small stress protein PASS1 1979965 3078281 lpg1773 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 small stress protein PASS1 YP_095799.1 1979015 D 272624 CDS YP_095800.1 52842001 3078189 1980237..1983065 1 NC_002942.5 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1983065 nrdA 3078189 nrdA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonucleotide-diphosphate reductase subunit alpha YP_095800.1 1980237 D 272624 CDS YP_095801.1 52842002 3078311 1983037..1984182 1 NC_002942.5 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 1984182 nrdB 3078311 nrdB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonucleotide-diphosphate reductase subunit beta YP_095801.1 1983037 D 272624 CDS YP_095802.1 52842003 3077682 1984497..1984982 1 NC_002942.5 hypothetical protein 1984982 3077682 lpg1776 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095802.1 1984497 D 272624 CDS YP_095803.1 52842004 3078261 complement(1985069..1986559) 1 NC_002942.5 lysine tRNA synthetase, heat inducible 1986559 lysU 3078261 lysU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lysine tRNA synthetase, heat inducible YP_095803.1 1985069 R 272624 CDS YP_095804.1 52842005 3078085 complement(1986556..1987563) 1 NC_002942.5 peptide chain release factor 2 1987563 prfB 3078085 prfB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide chain release factor 2 YP_095804.1 1986556 R 272624 CDS YP_095805.1 52842006 3078096 complement(1987723..1988124) 1 NC_002942.5 hypothetical protein 1988124 3078096 lpg1779 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095805.1 1987723 R 272624 CDS YP_095806.1 52842007 3078343 complement(1988121..1988942) 1 NC_002942.5 Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; flagellar motor protein MotD 1988942 motB 3078343 motB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor protein MotD YP_095806.1 1988121 R 272624 CDS YP_095807.1 52842008 3078242 complement(1988899..1989672) 1 NC_002942.5 homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC; flagellar motor protein 1989672 motC 3078242 motC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor protein YP_095807.1 1988899 R 272624 CDS YP_095808.2 161723249 3078407 complement(1989682..1990398) 1 NC_002942.5 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1990398 fliA 3078407 fliA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis sigma factor YP_095808.2 1989682 R 272624 CDS YP_095809.1 52842010 3077663 complement(1990495..1991382) 1 NC_002942.5 flagellar biosynthesis MinD 1991382 3077663 lpg1783 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis MinD YP_095809.1 1990495 R 272624 CDS YP_095810.1 52842011 3078206 complement(1991351..1992511) 1 NC_002942.5 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 1992511 flhF 3078206 flhF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis regulator FlhF YP_095810.1 1991351 R 272624 CDS YP_095811.1 52842012 3078301 complement(1992531..1994609) 1 NC_002942.5 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1994609 flhA 3078301 flhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis protein FlhA YP_095811.1 1992531 R 272624 CDS YP_095812.1 52842013 3078414 complement(1994606..1995757) 1 NC_002942.5 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1995757 flhB 3078414 flhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis protein FlhB YP_095812.1 1994606 R 272624 CDS YP_095813.1 52842014 3078194 complement(1995754..1996524) 1 NC_002942.5 flagellar biosynthetic protein FliR 1996524 fliR 3078194 fliR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthetic protein FliR YP_095813.1 1995754 R 272624 CDS YP_095814.1 52842015 3078319 complement(1996528..1996797) 1 NC_002942.5 flagellar biosynthetic protein FliQ 1996797 fliQ 3078319 fliQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthetic protein FliQ YP_095814.1 1996528 R 272624 CDS YP_095815.1 52842016 3078357 complement(1996806..1997555) 1 NC_002942.5 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1997555 fliP 3078357 fliP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar biosynthesis protein FliP YP_095815.1 1996806 R 272624 CDS YP_095816.1 52842017 3078169 complement(1997556..1997966) 1 NC_002942.5 flagellar assembly protein FliO 1997966 fliO 3078169 fliO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar assembly protein FliO YP_095816.1 1997556 R 272624 CDS YP_095817.1 52842018 3077694 complement(1997963..1998292) 1 NC_002942.5 flagellar motor switch protein FliN 1998292 3077694 lpg1791 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor switch protein FliN YP_095817.1 1997963 R 272624 CDS YP_095818.1 52842019 3077846 complement(1998302..1999369) 1 NC_002942.5 flagellar motor switch protein FliM 1999369 fliM 3077846 fliM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor switch protein FliM YP_095818.1 1998302 R 272624 CDS YP_095819.1 52842020 3078049 complement(1999808..2000062) 1 NC_002942.5 hypothetical protein 2000062 3078049 lpg1793 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095819.1 1999808 R 272624 CDS YP_095820.1 52842021 3078107 2000166..2001461 1 NC_002942.5 L-gululonolactone oxidase 2001461 3078107 lpg1794 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-gululonolactone oxidase YP_095820.1 2000166 D 272624 CDS YP_095821.1 52842022 3078365 2001413..2002180 1 NC_002942.5 short chain dehydrogenase/reductase oxidoreductase 2002180 3078365 lpg1795 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 short chain dehydrogenase/reductase oxidoreductase YP_095821.1 2001413 D 272624 CDS YP_095822.1 52842023 3078291 2002200..2003207 1 NC_002942.5 LysR family transcriptional regulator 2003207 3078291 lpg1796 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_095822.1 2002200 D 272624 CDS YP_095823.1 52842024 3078114 2004190..2005470 1 NC_002942.5 hypothetical protein 2005470 3078114 lpg1797 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095823.1 2004190 D 272624 CDS YP_095824.1 52842025 3078157 complement(2005655..2006851) 1 NC_002942.5 hypothetical protein 2006851 3078157 lpg1798 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095824.1 2005655 R 272624 CDS YP_095825.1 52842026 3078416 complement(2007376..2009958) 1 NC_002942.5 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2009958 alaS 3078416 alaS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alanyl-tRNA synthetase YP_095825.1 2007376 R 272624 CDS YP_095826.2 161723248 3078145 complement(2009976..2010428) 1 NC_002942.5 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2010428 recX 3078145 recX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 recombination regulator RecX YP_095826.2 2009976 R 272624 CDS YP_095827.1 52842028 3078279 complement(2010421..2011467) 1 NC_002942.5 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2011467 recA 3078279 recA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 recombinase A YP_095827.1 2010421 R 272624 CDS YP_095828.1 52842029 3078210 complement(2011392..2011712) 1 NC_002942.5 hypothetical protein 2011712 3078210 lpg1802 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095828.1 2011392 R 272624 CDS YP_095829.1 52842030 3078277 complement(2011770..2012705) 1 NC_002942.5 hypothetical protein 2012705 3078277 lpg1803 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095829.1 2011770 R 272624 CDS YP_095830.1 52842031 3078359 complement(2012997..2013491) 1 NC_002942.5 CinA-related competence damage protein 2013491 3078359 lpg1804 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CinA-related competence damage protein YP_095830.1 2012997 R 272624 CDS YP_095831.1 52842032 3078394 2014053..2016650 1 NC_002942.5 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2016650 mutS 3078394 mutS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA mismatch repair protein MutS YP_095831.1 2014053 D 272624 CDS YP_095832.1 52842033 3078086 2016663..2018351 1 NC_002942.5 hypothetical protein 2018351 3078086 lpg1806 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095832.1 2016663 D 272624 CDS YP_095833.1 52842034 3077764 2018348..2020888 1 NC_002942.5 hypothetical protein 2020888 3077764 lpg1807 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095833.1 2018348 D 272624 CDS YP_095834.1 52842035 3078406 2020922..2021917 1 NC_002942.5 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2021917 hemB 3078406 hemB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 delta-aminolevulinic acid dehydratase YP_095834.1 2020922 D 272624 CDS YP_095835.1 52842036 3078221 2022054..2022446 1 NC_002942.5 hypothetical protein 2022446 3078221 lpg1809 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095835.1 2022054 D 272624 CDS YP_095836.1 52842037 3078203 complement(2022744..2024222) 1 NC_002942.5 hypothetical protein 2024222 3078203 lpg1810 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095836.1 2022744 R 272624 CDS YP_095837.1 52842038 3078392 2024508..2027087 1 NC_002942.5 catalyzes the 4-phospho-L-aspartate from L-aspartate and the formation of lysine from meso-2,6-diaminoheptanedioate; bifunctional aspartate kinase/diaminopimelate decarboxylase 2027087 lysC 3078392 lysC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional aspartate kinase/diaminopimelate decarboxylase YP_095837.1 2024508 D 272624 CDS YP_095838.1 52842039 3078342 2027092..2030322 1 NC_002942.5 ATP-dependent DNA helicase 2030322 3078342 lpg1812 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent DNA helicase YP_095838.1 2027092 D 272624 CDS YP_095839.1 52842040 3078340 2030529..2031602 1 NC_002942.5 ATPase (Mrp) 2031602 mrp 3078340 mrp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATPase (Mrp) YP_095839.1 2030529 D 272624 CDS YP_095840.1 52842041 3078213 2031718..2032272 1 NC_002942.5 hypothetical protein 2032272 3078213 lpg1814 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095840.1 2031718 D 272624 CDS YP_095841.1 52842042 3078215 complement(2032320..2033210) 1 NC_002942.5 hydrogen peroxide-inducible genes activator OxyR 2033210 oxyR 3078215 oxyR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogen peroxide-inducible genes activator OxyR YP_095841.1 2032320 R 272624 CDS YP_095842.1 52842043 3078273 2033353..2034642 1 NC_002942.5 major facilitator family transporter 2034642 3078273 lpg1816 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_095842.1 2033353 D 272624 CDS YP_095843.1 52842044 3078248 complement(2034644..2035651) 1 NC_002942.5 hypothetical protein 2035651 3078248 lpg1817 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095843.1 2034644 R 272624 CDS YP_095844.1 52842045 3078030 complement(2035596..2036567) 1 NC_002942.5 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 2036567 lpxK 3078030 lpxK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tetraacyldisaccharide 4'-kinase YP_095844.1 2035596 R 272624 CDS YP_095845.1 52842046 3078347 complement(2036567..2038360) 1 NC_002942.5 lipid ABC transporter permease/ATP-binding protein 2038360 3078347 lpg1819 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipid ABC transporter permease/ATP-binding protein YP_095845.1 2036567 R 272624 CDS YP_095846.1 52842047 3078233 complement(2038420..2039226) 1 NC_002942.5 hypothetical protein 2039226 3078233 lpg1820 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095846.1 2038420 R 272624 CDS YP_095847.1 52842048 3078164 complement(2039223..2040389) 1 NC_002942.5 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2040389 pyrD 3078164 pyrD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydroorotate dehydrogenase 2 YP_095847.1 2039223 R 272624 CDS YP_095848.1 52842049 3078193 complement(2040510..2041529) 1 NC_002942.5 hypothetical protein 2041529 3078193 lpg1822 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095848.1 2040510 R 272624 CDS YP_095849.1 52842050 3078415 complement(2041557..2042243) 1 NC_002942.5 hypothetical protein 2042243 3078415 lpg1823 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095849.1 2041557 R 272624 CDS YP_095850.1 52842051 3078077 2042569..2043738 1 NC_002942.5 acyl CoA dehydrogenase 2043738 3078077 lpg1824 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA dehydrogenase YP_095850.1 2042569 D 272624 CDS YP_095851.1 52842052 3078270 2043750..2044934 1 NC_002942.5 acyl CoA C-acetyltransferase 2044934 atoB 3078270 atoB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA C-acetyltransferase YP_095851.1 2043750 D 272624 CDS YP_095852.1 52842053 3078139 2045066..2045386 1 NC_002942.5 hypothetical protein 2045386 3078139 lpg1826 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095852.1 2045066 D 272624 CDS YP_095853.1 52842054 3078399 2045396..2047003 1 NC_002942.5 propionyl CoA carboxylase subunit beta 2047003 3078399 lpg1827 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 propionyl CoA carboxylase subunit beta YP_095853.1 2045396 D 272624 CDS YP_095854.1 52842055 3078216 2046969..2047817 1 NC_002942.5 enoyl CoA hydratase 2047817 3078216 lpg1828 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enoyl CoA hydratase YP_095854.1 2046969 D 272624 CDS YP_095855.1 52842056 3078320 2047741..2049774 1 NC_002942.5 acyl CoA carboxylase subunit alpha 2049774 3078320 lpg1829 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA carboxylase subunit alpha YP_095855.1 2047741 D 272624 CDS YP_095856.1 52842057 3078292 2049785..2050693 1 NC_002942.5 hydroxymethylglutaryl-CoA lyase 2050693 mvaB 3078292 mvaB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydroxymethylglutaryl-CoA lyase YP_095856.1 2049785 D 272624 CDS YP_095857.1 52842058 3078318 2050790..2052790 1 NC_002942.5 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 2052790 3078318 lpg1831 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetoacetyl-CoA synthetase YP_095857.1 2050790 D 272624 CDS YP_095858.1 52842059 3078348 complement(2052959..2053375) 1 NC_002942.5 hypothetical protein 2053375 3078348 lpg1832 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095858.1 2052959 R 272624 CDS YP_095859.1 52842060 3077720 2053752..2054852 1 NC_002942.5 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 2054852 metN 3077720 metN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DL-methionine transporter ATP-binding subunit YP_095859.1 2053752 D 272624 CDS YP_095860.1 52842061 3078388 2054830..2055477 1 NC_002942.5 ATP-binding protein, permease 2055477 metI 3078388 metI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-binding protein, permease YP_095860.1 2054830 D 272624 CDS YP_095861.1 52842062 3078172 2055478..2056269 1 NC_002942.5 hypothetical protein 2056269 3078172 lpg1835 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095861.1 2055478 D 272624 CDS YP_095862.1 52842063 3078374 2056349..2057767 1 NC_002942.5 coiled coil domain-containing protein 2057767 3078374 lpg1836 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coiled coil domain-containing protein YP_095862.1 2056349 D 272624 CDS YP_095863.1 52842064 3078037 complement(2058256..2058987) 1 NC_002942.5 SAM-dependent methyltransferase 2058987 3078037 lpg1837 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SAM-dependent methyltransferase YP_095863.1 2058256 R 272624 CDS YP_095864.1 52842065 3078032 complement(2058990..2059520) 1 NC_002942.5 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 2059520 3078032 lpg1838 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D,D-heptose 1,7-bisphosphate phosphatase YP_095864.1 2058990 R 272624 CDS YP_095865.1 52842066 3078223 complement(2059526..2061592) 1 NC_002942.5 glycyl tRNA synthetase subunit beta 2061592 glyS 3078223 glyS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycyl tRNA synthetase subunit beta YP_095865.1 2059526 R 272624 CDS YP_095866.1 52842067 3078308 complement(2061582..2062505) 1 NC_002942.5 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 2062505 glyQ 3078308 glyQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycyl-tRNA synthetase subunit alpha YP_095866.1 2061582 R 272624 CDS YP_095867.1 52842068 3078098 complement(2062722..2063507) 1 NC_002942.5 hypothetical protein 2063507 com1 3078098 com1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095867.1 2062722 R 272624 CDS YP_095868.2 161723247 3078161 complement(2063715..2065880) 1 NC_002942.5 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 2065880 uvrD 3078161 uvrD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-dependent helicase II YP_095868.2 2063715 R 272624 CDS YP_095869.1 52842070 3078112 2066101..2067060 1 NC_002942.5 proline iminopeptidase 2067060 pip 3078112 pip Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proline iminopeptidase YP_095869.1 2066101 D 272624 CDS YP_095870.1 52842071 3078272 2067054..2067491 1 NC_002942.5 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2067491 dtD 3078272 dtD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-tyrosyl-tRNA(Tyr) deacylase YP_095870.1 2067054 D 272624 CDS YP_095871.1 52842072 3078303 2067708..2068490 1 NC_002942.5 lipoprotein VacJ-like 2068490 vacJ 3078303 vacJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein VacJ-like YP_095871.1 2067708 D 272624 CDS YP_095872.1 52842073 3078313 complement(2068599..2069561) 1 NC_002942.5 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2069561 gshB 3078313 gshB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione synthetase YP_095872.1 2068599 R 272624 CDS YP_095873.1 52842074 3078306 complement(2069558..2070853) 1 NC_002942.5 glutamate--cysteine ligase 2070853 3078306 lpg1847 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamate--cysteine ligase YP_095873.1 2069558 R 272624 CDS YP_095874.1 52842075 3078265 2071231..2072127 1 NC_002942.5 ABC transporter transmembrane permease,permeases of drug/metabolite transporter type 2072127 3078265 lpg1848 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter transmembrane permease,permeases of drug/metabolite transporter type YP_095874.1 2071231 D 272624 CDS YP_095875.1 52842076 3078371 2072131..2072412 1 NC_002942.5 hypothetical protein 2072412 3078371 lpg1849 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095875.1 2072131 D 272624 CDS YP_095876.1 52842077 3078176 2072399..2072749 1 NC_002942.5 rhodanese domain-containing protein 2072749 3078176 lpg1850 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rhodanese domain-containing protein YP_095876.1 2072399 D 272624 CDS YP_095877.1 52842078 3078254 complement(2072773..2073435) 1 NC_002942.5 hypothetical protein 2073435 3078254 lpg1851 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095877.1 2072773 R 272624 CDS YP_095878.1 52842079 3078190 2073781..2075442 1 NC_002942.5 alkaline phosphatase 2075442 3078190 lpg1852 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkaline phosphatase YP_095878.1 2073781 D 272624 CDS YP_095879.1 52842080 3078136 2075411..2076133 1 NC_002942.5 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2076133 udk 3078136 udk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uridine kinase YP_095879.1 2075411 D 272624 CDS YP_095880.1 52842081 3078106 2076229..2077035 1 NC_002942.5 enoyl reductase 2077035 fabI 3078106 fabI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enoyl reductase YP_095880.1 2076229 D 272624 CDS YP_095881.1 52842082 3078338 complement(2077573..2079447) 1 NC_002942.5 hypothetical protein 2079447 ppiD 3078338 ppiD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095881.1 2077573 R 272624 CDS YP_095882.1 52842083 3078113 complement(2079705..2080007) 1 NC_002942.5 hypothetical protein 2080007 hupB 3078113 hupB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095882.1 2079705 R 272624 CDS YP_095883.1 52842084 3078237 complement(2080112..2082562) 1 NC_002942.5 hypothetical protein 2082562 lon 3078237 lon Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095883.1 2080112 R 272624 CDS YP_095884.1 52842085 3078395 complement(2082800..2084080) 1 NC_002942.5 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2084080 clpX 3078395 clpX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent protease ATP-binding subunit ClpX YP_095884.1 2082800 R 272624 CDS YP_095885.1 52842086 3078362 complement(2084215..2084859) 1 NC_002942.5 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2084859 clpP 3078362 clpP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent Clp protease proteolytic subunit YP_095885.1 2084215 R 272624 CDS YP_095886.1 52842087 3078325 complement(2084862..2086193) 1 NC_002942.5 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2086193 tig 3078325 tig Legionella pneumophila subsp. pneumophila str. Philadelphia 1 trigger factor YP_095886.1 2084862 R 272624 CDS YP_095887.1 52842088 3077677 2087055..2088281 1 NC_002942.5 site specific recombinase, phage integrase 2088281 3077677 lpg1867 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 site specific recombinase, phage integrase YP_095887.1 2087055 D 272624 CDS YP_095888.1 52842089 3078224 2088377..2090254 1 NC_002942.5 ABC transporter ATP-binding protein 2090254 3078224 lpg1868 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_095888.1 2088377 D 272624 CDS YP_095889.1 52842090 3078344 complement(2090282..2090956) 1 NC_002942.5 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2090956 rnc 3078344 rnc Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease III YP_095889.1 2090282 R 272624 CDS YP_095890.1 52842091 3078120 complement(2090946..2091338) 1 NC_002942.5 transmembrane protein 2091338 3078120 lpg1870 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095890.1 2090946 R 272624 CDS YP_095891.1 52842092 3078387 complement(2091350..2092132) 1 NC_002942.5 signal peptidase I (lepB-1) 2092132 lepB-1 3078387 lepB-1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptidase I (lepB-1) YP_095891.1 2091350 R 272624 CDS YP_095892.1 52842093 3078155 complement(2092213..2094045) 1 NC_002942.5 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2094045 lepA 3078155 lepA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP-binding protein LepA YP_095892.1 2092213 R 272624 CDS YP_095893.1 52842094 3078245 2094213..2095256 1 NC_002942.5 membrane bound lytic murein transglycosylase 2095256 3078245 lpg1873 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane bound lytic murein transglycosylase YP_095893.1 2094213 D 272624 CDS YP_095894.1 52842095 3078197 2095331..2096470 1 NC_002942.5 general secretion pathway protein L 2096470 3078197 lpg1874 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 general secretion pathway protein L YP_095894.1 2095331 D 272624 CDS YP_095895.1 52842096 3078400 2096467..2096937 1 NC_002942.5 general secretion pathway protein M-type YghD 2096937 yghD 3078400 yghD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 general secretion pathway protein M-type YghD YP_095895.1 2096467 D 272624 CDS YP_095896.1 52842097 3078142 complement(2097042..2097575) 1 NC_002942.5 hypothetical protein 2097575 3078142 lpg1876 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095896.1 2097042 R 272624 CDS YP_095897.1 52842098 3078372 2097822..2099174 1 NC_002942.5 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 2099174 3078372 lpg1877 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_095897.1 2097822 D 272624 CDS YP_095898.1 52842099 3078314 complement(2099864..2100958) 1 NC_002942.5 hypothetical protein 2100958 3078314 lpg1881 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095898.1 2099864 R 272624 CDS YP_095899.1 52842100 3078408 complement(2101020..2101460) 1 NC_002942.5 lactoylglutathione lyase 2101460 gloA 3078408 gloA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lactoylglutathione lyase YP_095899.1 2101020 R 272624 CDS YP_095900.1 52842101 3078288 2101695..2102222 1 NC_002942.5 hypothetical protein 2102222 3078288 lpg1883 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095900.1 2101695 D 272624 CDS YP_095901.1 52842102 3078078 2102459..2103676 1 NC_002942.5 conserved gene; coiled-coil-containing protein; microtubule binding protein 2103676 legC2 3078078 legC2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 microtubule binding protein YP_095901.1 2102459 D 272624 CDS YP_095902.1 52842103 3077840 2103996..2104310 1 NC_002942.5 hypothetical protein 2104310 3077840 lpg1885 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095902.1 2103996 D 272624 CDS YP_095903.1 52842104 3078351 complement(2104447..2104722) 1 NC_002942.5 catalyzes the hydrolysis of acylphosphate; acylphosphatase 2104722 3078351 lpg1886 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acylphosphatase YP_095903.1 2104447 R 272624 CDS YP_095904.1 52842105 3078327 2104879..2105232 1 NC_002942.5 hypothetical protein 2105232 3078327 lpg1887 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095904.1 2104879 D 272624 CDS YP_095905.1 52842106 3078048 complement(2105414..2106745) 1 NC_002942.5 hypothetical protein 2106745 3078048 lpg1888 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095905.1 2105414 R 272624 CDS YP_095906.1 52842107 3078208 2106974..2107939 1 NC_002942.5 lipase 2107939 3078208 lpg1889 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipase YP_095906.1 2106974 D 272624 CDS YP_095907.1 52842108 3078305 complement(2108003..2109724) 1 NC_002942.5 conserved gene, like GALA proteins; hypothetical protein 2109724 legLC8 3078305 legLC8 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095907.1 2108003 R 272624 CDS YP_095908.1 52842109 3078381 2109800..2110102 1 NC_002942.5 hypothetical protein 2110102 3078381 lpg1891 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095908.1 2109800 D 272624 CDS YP_095909.1 52842110 3078368 2110192..2110575 1 NC_002942.5 hypothetical protein 2110575 3078368 lpg1892 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095909.1 2110192 D 272624 CDS YP_095910.1 52842111 3078025 complement(2110585..2111865) 1 NC_002942.5 major facilitator family transporter 2111865 3078025 lpg1893 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_095910.1 2110585 R 272624 CDS YP_095911.1 52842112 3078275 2112309..2113622 1 NC_002942.5 chloride channel protein (voltage gated) 2113622 3078275 lpg1894 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chloride channel protein (voltage gated) YP_095911.1 2112309 D 272624 CDS YP_095912.1 52842113 3078294 2113708..2114232 1 NC_002942.5 hypothetical protein 2114232 3078294 lpg1895 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095912.1 2113708 D 272624 CDS YP_095913.1 52842114 3078135 2114494..2114973 1 NC_002942.5 hypothetical protein 2114973 ychJ 3078135 ychJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095913.1 2114494 D 272624 CDS YP_095914.1 52842115 3078360 2114993..2116798 1 NC_002942.5 glutathione-regulated potassium efflux system 2116798 3078360 lpg1897 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione-regulated potassium efflux system YP_095914.1 2114993 D 272624 CDS YP_095915.1 52842116 3078079 2116840..2117754 1 NC_002942.5 methanol dehydrogenase regulatory protein 2117754 3078079 lpg1898 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methanol dehydrogenase regulatory protein YP_095915.1 2116840 D 272624 CDS YP_095916.1 52842117 3078393 2117778..2118701 1 NC_002942.5 transmembrane protein 2118701 3078393 lpg1899 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_095916.1 2117778 D 272624 CDS YP_095917.1 52842118 3078333 2118701..2120689 1 NC_002942.5 transglutaminase 2120689 3078333 lpg1900 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transglutaminase YP_095917.1 2118701 D 272624 CDS YP_095918.1 52842119 3078220 2120771..2121958 1 NC_002942.5 hypothetical protein 2121958 3078220 lpg1901 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095918.1 2120771 D 272624 CDS YP_095919.1 52842120 3078404 2122066..2122392 1 NC_002942.5 hypothetical protein 2122392 3078404 lpg1902 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095919.1 2122066 D 272624 CDS YP_095920.1 52842121 3078329 2122839..2123741 1 NC_002942.5 hydrolase 2123741 3078329 lpg1903 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrolase YP_095920.1 2122839 D 272624 CDS YP_095921.1 52842122 3077772 complement(2123771..2124673) 1 NC_002942.5 hypothetical protein 2124673 3077772 lpg1904 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095921.1 2123771 R 272624 CDS YP_095922.1 52842123 3078951 2124889..2126070 1 NC_002942.5 ectonucleoside triphosphate diphosphohydrolase I 2126070 3078951 lpg1905 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ectonucleoside triphosphate diphosphohydrolase I YP_095922.1 2124889 D 272624 CDS YP_095923.1 52842124 3078187 complement(2126075..2126608) 1 NC_002942.5 transporting ATPase 2126608 3078187 lpg1906 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporting ATPase YP_095923.1 2126075 R 272624 CDS YP_095924.1 52842125 3078376 complement(2126619..2128424) 1 NC_002942.5 hypothetical protein 2128424 3078376 lpg1907 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095924.1 2126619 R 272624 CDS YP_095925.1 52842126 3078287 complement(2128741..2129352) 1 NC_002942.5 glutathione S-transferase 2129352 gst 3078287 gst Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione S-transferase YP_095925.1 2128741 R 272624 CDS YP_095926.1 52842127 3078043 complement(2129542..2130546) 1 NC_002942.5 hypothetical protein 2130546 3078043 lpg1909 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095926.1 2129542 R 272624 CDS YP_095927.1 52842128 3078149 complement(2130578..2131840) 1 NC_002942.5 D-alanyl-D-alanine carboxypeptidase 2131840 3078149 lpg1910 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanyl-D-alanine carboxypeptidase YP_095927.1 2130578 R 272624 CDS YP_095928.1 52842129 3078160 complement(2132087..2133571) 1 NC_002942.5 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2133571 gltX 3078160 gltX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamyl-tRNA synthetase YP_095928.1 2132087 R 272624 CDS YP_095929.1 52842130 3078432 2133598..2136330 1 NC_002942.5 sensory box histidine kinase/response regulator 2136330 3078432 lpg1912 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box histidine kinase/response regulator YP_095929.1 2133598 D 272624 CDS YP_095930.1 52842131 3078244 2136427..2137671 1 NC_002942.5 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 2137671 3078244 lpg1913 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 6-phosphofructokinase YP_095930.1 2136427 D 272624 CDS YP_095931.1 52842132 3078334 complement(2137668..2138096) 1 NC_002942.5 fimbrial protein, type IV pilin, PilE 2138096 pilE 3078334 pilE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fimbrial protein, type IV pilin, PilE YP_095931.1 2137668 R 272624 CDS YP_095932.1 52842133 3078099 complement(2138278..2138700) 1 NC_002942.5 Tfp pilus assembly protein, major type IV pilin class A 2138700 pilE 3078099 pilE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Tfp pilus assembly protein, major type IV pilin class A YP_095932.1 2138278 R 272624 CDS YP_095933.1 52842134 3078241 2138991..2139308 1 NC_002942.5 regulator of murein genes BolA 2139308 bolA 3078241 bolA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 regulator of murein genes BolA YP_095933.1 2138991 D 272624 CDS YP_095934.1 52842135 3077856 2139383..2140804 1 NC_002942.5 amino acid antiporter 2140804 3077856 lpg1917 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid antiporter YP_095934.1 2139383 D 272624 CDS YP_095935.1 52842136 3078354 complement(2140935..2142365) 1 NC_002942.5 hypothetical protein 2142365 3078354 lpg1918 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095935.1 2140935 R 272624 CDS YP_095936.1 52842137 3078377 complement(2142611..2143363) 1 NC_002942.5 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 2143363 kdsB 3078377 kdsB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-deoxy-manno-octulosonate cytidylyltransferase YP_095936.1 2142611 R 272624 CDS YP_095937.1 52842138 3078300 complement(2143360..2143539) 1 NC_002942.5 tetraacyldisaccharide-1-P-4'-kinase 2143539 lpxK 3078300 lpxK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tetraacyldisaccharide-1-P-4'-kinase YP_095937.1 2143360 R 272624 CDS YP_095938.1 52842139 3077820 complement(2143532..2144203) 1 NC_002942.5 glycoprotease 2144203 3077820 lpg1921 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycoprotease YP_095938.1 2143532 R 272624 CDS YP_095939.1 52842140 3078328 complement(2144181..2146181) 1 NC_002942.5 DEAD/DEAH box helicase 2146181 3078328 lpg1922 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DEAD/DEAH box helicase YP_095939.1 2144181 R 272624 CDS YP_095940.1 52842141 3078182 complement(2146127..2146462) 1 NC_002942.5 ferredoxin II (4Fe-4S) 2146462 3078182 lpg1923 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ferredoxin II (4Fe-4S) YP_095940.1 2146127 R 272624 CDS YP_095941.1 52842142 3078109 2146745..2149537 1 NC_002942.5 hypothetical protein 2149537 3078109 lpg1924 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095941.1 2146745 D 272624 CDS YP_095942.1 52842143 3078396 2149854..2152499 1 NC_002942.5 hypothetical protein 2152499 3078396 lpg1925 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095942.1 2149854 D 272624 CDS YP_095943.1 52842144 3078304 2152569..2153132 1 NC_002942.5 hypothetical protein 2153132 3078304 lpg1926 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095943.1 2152569 D 272624 CDS YP_095944.1 52842145 3078129 2153208..2153477 1 NC_002942.5 hypothetical protein 2153477 3078129 lpg1927 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095944.1 2153208 D 272624 CDS YP_095945.1 52842146 3078141 2153489..2154415 1 NC_002942.5 hypothetical protein 2154415 indA 3078141 indA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095945.1 2153489 D 272624 CDS YP_095946.1 52842147 3078251 2154720..2155871 1 NC_002942.5 hypothetical protein 2155871 3078251 lpg1930 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095946.1 2154720 D 272624 CDS YP_095947.1 52842148 3078425 complement(2156663..2157406) 1 NC_002942.5 hypothetical protein 2157406 3078425 lpg1931 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095947.1 2156663 R 272624 CDS YP_095948.1 52842149 3078201 2157782..2158096 1 NC_002942.5 hypothetical protein 2158096 3078201 lpg1932 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095948.1 2157782 D 272624 CDS YP_095949.1 52842150 3078111 complement(2158158..2158772) 1 NC_002942.5 hypothetical protein 2158772 3078111 lpg1933 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095949.1 2158158 R 272624 CDS YP_095950.1 52842151 3078928 complement(2158922..2160232) 1 NC_002942.5 hypothetical protein 2160232 3078928 lpg1934 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095950.1 2158922 R 272624 CDS YP_095951.1 52842152 3077750 complement(2160204..2160485) 1 NC_002942.5 hypothetical protein 2160485 3077750 lpg1935 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095951.1 2160204 R 272624 CDS YP_095952.1 52842153 3078434 complement(2160726..2162618) 1 NC_002942.5 methoxymalonyl CoA synthase 2162618 3078434 lpg1936 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methoxymalonyl CoA synthase YP_095952.1 2160726 R 272624 CDS YP_095953.1 52842154 3078391 complement(2162633..2163694) 1 NC_002942.5 pyoverdine biosynthesis regulatory gene SyrP-like 2163694 3078391 lpg1937 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyoverdine biosynthesis regulatory gene SyrP-like YP_095953.1 2162633 R 272624 CDS YP_095954.1 52842155 3078097 2164322..2165803 1 NC_002942.5 coenzyme F390 synthetase 2165803 3078097 lpg1938 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coenzyme F390 synthetase YP_095954.1 2164322 D 272624 CDS YP_095955.1 52842156 3078256 complement(2166115..2167431) 1 NC_002942.5 polyketide synthase 2167431 3078256 lpg1939 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polyketide synthase YP_095955.1 2166115 R 272624 CDS YP_095956.1 52842157 3078419 complement(2167602..2169122) 1 NC_002942.5 peptide synthetase 2169122 3078419 lpg1940 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide synthetase YP_095956.1 2167602 R 272624 CDS YP_095957.1 52842158 3078240 complement(2169139..2170266) 1 NC_002942.5 acyl CoA dehydrogenase 2170266 3078240 lpg1941 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA dehydrogenase YP_095957.1 2169139 R 272624 CDS YP_095958.1 52842159 3078234 complement(2170297..2171151) 1 NC_002942.5 3-hydroxyacyl CoA dehydrogenase 2171151 3078234 lpg1942 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxyacyl CoA dehydrogenase YP_095958.1 2170297 R 272624 CDS YP_095959.1 52842160 3078337 complement(2171262..2171519) 1 NC_002942.5 hypothetical protein 2171519 3078337 lpg1943 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095959.1 2171262 R 272624 CDS YP_095960.1 52842161 3078427 2171659..2172705 1 NC_002942.5 hypothetical protein 2172705 3078427 lpg1944 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095960.1 2171659 D 272624 CDS YP_095961.1 52842162 3078128 complement(2172886..2173869) 1 NC_002942.5 3',5'-cyclic-nucleotide phosphodiesterase 2173869 3078128 lpg1945 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3',5'-cyclic-nucleotide phosphodiesterase YP_095961.1 2172886 R 272624 CDS YP_095962.1 52842163 3078421 complement(2173974..2174645) 1 NC_002942.5 LuxR family transcriptional regulator 2174645 3078421 lpg1946 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LuxR family transcriptional regulator YP_095962.1 2173974 R 272624 CDS YP_095963.1 52842164 3078436 2174909..2175658 1 NC_002942.5 hypothetical protein 2175658 3078436 lpg1947 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095963.1 2174909 D 272624 CDS YP_095964.1 52842165 3078138 complement(2175670..2176677) 1 NC_002942.5 FLJ00180 protein; hypothetical protein 2176677 legLC4 3078138 legLC4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095964.1 2175670 R 272624 CDS YP_095965.1 52842166 3078070 complement(2176986..2178326) 1 NC_002942.5 hypothetical protein 2178326 3078070 lpg1949 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095965.1 2176986 R 272624 CDS YP_095966.1 52842167 3077847 2178619..2179743 1 NC_002942.5 guanine nucleotide exchange protein 2179743 sec7 3077847 sec7 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanine nucleotide exchange protein YP_095966.1 2178619 D 272624 CDS YP_095967.1 52842168 3078584 2180075..2180950 1 NC_002942.5 hypothetical protein 2180950 3078584 lpg1951 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095967.1 2180075 D 272624 CDS YP_095968.1 52842169 3078472 2180947..2181756 1 NC_002942.5 3',5'-cyclic-nucleotide phosphodiesterase 2181756 3078472 lpg1952 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3',5'-cyclic-nucleotide phosphodiesterase YP_095968.1 2180947 D 272624 CDS YP_095969.1 52842170 3078464 complement(2181810..2184092) 1 NC_002942.5 hypothetical protein 2184092 legC4 3078464 legC4 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095969.1 2181810 R 272624 CDS YP_095970.1 52842171 3078473 complement(2184483..2185058) 1 NC_002942.5 hypothetical protein 2185058 3078473 lpg1954 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095970.1 2184483 R 272624 CDS YP_095971.1 52842172 3078467 complement(2185359..2186648) 1 NC_002942.5 permease 2186648 3078467 lpg1955 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 permease YP_095971.1 2185359 R 272624 CDS YP_095972.1 52842173 3078449 complement(2186648..2187751) 1 NC_002942.5 chloromuconate cycloisomerase 2187751 3078449 lpg1956 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chloromuconate cycloisomerase YP_095972.1 2186648 R 272624 CDS YP_095973.1 52842174 3078457 2187982..2189373 1 NC_002942.5 EbhA protein 2189373 3078457 lpg1957 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 EbhA protein YP_095973.1 2187982 D 272624 CDS YP_095974.1 52842175 3078463 2189637..2191265 1 NC_002942.5 FLJ00180 protein; hypothetical protein 2191265 legL5 3078463 legL5 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095974.1 2189637 D 272624 CDS YP_095975.1 52842176 3078448 2191518..2193512 1 NC_002942.5 hypothetical protein 2193512 3078448 lpg1959 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095975.1 2191518 D 272624 CDS YP_095976.1 52842177 3078373 2193697..2194470 1 NC_002942.5 hypothetical protein 2194470 3078373 lpg1960 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095976.1 2193697 D 272624 CDS YP_095977.1 52842178 3078455 complement(2194507..2196039) 1 NC_002942.5 hypothetical protein 2196039 3078455 lpg1961 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095977.1 2194507 R 272624 CDS YP_095978.1 52842179 3078454 2196167..2196733 1 NC_002942.5 peptidyl-prolyl cis-trans isomerase 2196733 3078454 lpg1962 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidyl-prolyl cis-trans isomerase YP_095978.1 2196167 D 272624 CDS YP_095979.1 52842180 3078446 complement(2196799..2198898) 1 NC_002942.5 hypothetical protein 2198898 3078446 lpg1963 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095979.1 2196799 R 272624 CDS YP_095980.1 52842181 3078475 2199220..2200530 1 NC_002942.5 hypothetical protein 2200530 3078475 lpg1964 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095980.1 2199220 D 272624 CDS YP_095981.1 52842182 3078456 complement(2200794..2203760) 1 NC_002942.5 hypothetical protein 2203760 3078456 lpg1965 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095981.1 2200794 R 272624 CDS YP_095982.1 52842183 3078470 complement(2204165..2205730) 1 NC_002942.5 hypothetical protein 2205730 3078470 lpg1966 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095982.1 2204165 R 272624 CDS YP_095983.1 52842184 3078466 2206539..2207105 1 NC_002942.5 TetR family transcriptional regulator 2207105 3078466 lpg1967 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TetR family transcriptional regulator YP_095983.1 2206539 D 272624 CDS YP_095984.1 52842185 3078474 2207148..2207912 1 NC_002942.5 hypothetical protein 2207912 3078474 lpg1968 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095984.1 2207148 D 272624 CDS YP_095985.1 52842186 3078477 complement(2208464..2210371) 1 NC_002942.5 hypothetical protein 2210371 3078477 lpg1969 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095985.1 2208464 R 272624 CDS YP_095986.1 52842187 3078460 complement(2210715..2211338) 1 NC_002942.5 glutathione S-transferase 2211338 3078460 lpg1970 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione S-transferase YP_095986.1 2210715 R 272624 CDS YP_095987.1 52842188 3078445 complement(2211372..2211791) 1 NC_002942.5 organic hydroperoxide resistance protein OsmC, redox protein, regulator of sulfide bond formation 2211791 3078445 lpg1971 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 organic hydroperoxide resistance protein OsmC, redox protein, regulator of sulfide bond formation YP_095987.1 2211372 R 272624 CDS YP_095988.1 52842189 3078452 complement(2212015..2212392) 1 NC_002942.5 hypothetical protein 2212392 3078452 lpg1972 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095988.1 2212015 R 272624 CDS YP_095989.1 52842190 3078468 2212856..2213098 1 NC_002942.5 hypothetical protein 2213098 3078468 lpg1973 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095989.1 2212856 D 272624 CDS YP_095990.1 52842191 3078453 2213603..2214496 1 NC_002942.5 major outer membrane protein 2214496 3078453 lpg1974 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major outer membrane protein YP_095990.1 2213603 D 272624 CDS YP_095991.1 52842192 3078480 2214817..2215467 1 NC_002942.5 hypothetical protein 2215467 3078480 lpg1975 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095991.1 2214817 D 272624 CDS YP_095992.1 52842193 3078481 2215443..2216303 1 NC_002942.5 conserved gene; RCC-1; UVB-resistance protein UVR8 2216303 legG1 3078481 legG1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UVB-resistance protein UVR8 YP_095992.1 2215443 D 272624 CDS YP_095993.1 52842194 3078489 2216481..2217077 1 NC_002942.5 ThiJ/PfpI family intracellular protease 2217077 3078489 lpg1977 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ThiJ/PfpI family intracellular protease YP_095993.1 2216481 D 272624 CDS YP_095994.1 52842195 3078498 complement(2217148..2219082) 1 NC_002942.5 teichoic acid biosynthesis protein 2219082 3078498 lpg1978 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 teichoic acid biosynthesis protein YP_095994.1 2217148 R 272624 CDS YP_095995.1 52842196 3078503 2219318..2220685 1 NC_002942.5 hypothetical protein 2220685 3078503 lpg1979 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095995.1 2219318 D 272624 CDS YP_095996.1 52842197 3078514 2220682..2220984 1 NC_002942.5 hypothetical protein 2220984 3078514 lpg1980 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095996.1 2220682 D 272624 CDS YP_095997.1 52842198 3078539 2221158..2221454 1 NC_002942.5 hypothetical protein 2221454 3078539 lpg1981 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095997.1 2221158 D 272624 CDS YP_095998.1 52842199 3078546 2221477..2222520 1 NC_002942.5 hypothetical protein 2222520 3078546 lpg1982 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_095998.1 2221477 D 272624 CDS YP_095999.1 52842200 3078552 2222680..2223885 1 NC_002942.5 3-hydroxy-3-methylglutaryl-CoA reductase 2223885 3078552 lpg1983 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxy-3-methylglutaryl-CoA reductase YP_095999.1 2222680 D 272624 CDS YP_096000.1 52842201 3078561 2223905..2224642 1 NC_002942.5 hydantoin racemase 2224642 hyuE 3078561 hyuE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydantoin racemase YP_096000.1 2223905 D 272624 CDS YP_096001.1 52842202 3078569 complement(2224682..2225995) 1 NC_002942.5 guanine aminohydrolase 2225995 gad 3078569 gad Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanine aminohydrolase YP_096001.1 2224682 R 272624 CDS YP_096002.1 52842203 3078573 complement(2226164..2229016) 1 NC_002942.5 hypothetical protein 2229016 3078573 lpg1986 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096002.1 2226164 R 272624 CDS YP_096003.1 52842204 3078593 complement(2229193..2229660) 1 NC_002942.5 phosphohistidine phosphatase SixA 2229660 3078593 lpg1987 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphohistidine phosphatase SixA YP_096003.1 2229193 R 272624 CDS YP_096004.1 52842205 3078599 2229735..2230280 1 NC_002942.5 dihydrofolate reductase 2230280 3078599 lpg1988 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrofolate reductase YP_096004.1 2229735 D 272624 CDS YP_096005.1 52842206 3078603 2230379..2230795 1 NC_002942.5 glutathione S-transferase 2230795 3078603 lpg1989 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione S-transferase YP_096005.1 2230379 D 272624 CDS YP_096006.1 52842207 3078620 complement(2230973..2231707) 1 NC_002942.5 hypothetical protein 2231707 3078620 lpg1990 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096006.1 2230973 R 272624 CDS YP_096007.1 52842208 3078628 complement(2231815..2232465) 1 NC_002942.5 hypothetical protein 2232465 3078628 lpg1991 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096007.1 2231815 R 272624 CDS YP_096008.1 52842209 3078131 complement(2232545..2233093) 1 NC_002942.5 hypothetical protein 2233093 3078131 lpg1992 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096008.1 2232545 R 272624 CDS YP_096009.1 52842210 3078635 2233519..2234397 1 NC_002942.5 polysaccharide deacetylase 2234397 3078635 lpg1993 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polysaccharide deacetylase YP_096009.1 2233519 D 272624 CDS YP_096010.1 52842211 3078640 complement(2234514..2235707) 1 NC_002942.5 hypothetical protein 2235707 3078640 lpg1994 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096010.1 2234514 R 272624 CDS YP_096011.1 52842212 3078645 complement(2235817..2236374) 1 NC_002942.5 hypothetical protein 2236374 3078645 lpg1995 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096011.1 2235817 R 272624 CDS YP_096012.1 52842213 3078653 complement(2236371..2237177) 1 NC_002942.5 hypothetical protein 2237177 3078653 lpg1996 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096012.1 2236371 R 272624 CDS YP_096013.1 52842214 3078612 complement(2237116..2237430) 1 NC_002942.5 hypothetical protein 2237430 3078612 lpg1997 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096013.1 2237116 R 272624 CDS YP_096014.1 52842215 3078542 2237572..2238699 1 NC_002942.5 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2238699 hisC2 3078542 hisC2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 histidinol-phosphate aminotransferase YP_096014.1 2237572 D 272624 CDS YP_096015.1 52842216 3078530 2238736..2239077 1 NC_002942.5 pterin 4 alpha carbinolamine dehydratase 2239077 3078530 lpg1999 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pterin 4 alpha carbinolamine dehydratase YP_096015.1 2238736 D 272624 CDS YP_096016.1 52842217 3078476 complement(2239250..2240167) 1 NC_002942.5 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 2240167 secF 3078476 secF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecF YP_096016.1 2239250 R 272624 CDS YP_096017.1 52842218 3078609 complement(2240180..2242036) 1 NC_002942.5 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 2242036 secD 3078609 secD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecD YP_096017.1 2240180 R 272624 CDS YP_096018.1 52842219 3078637 complement(2242058..2242393) 1 NC_002942.5 transmembrane protein YajC, preprotein translocase subunit 2242393 yajC 3078637 yajC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YajC, preprotein translocase subunit YP_096018.1 2242058 R 272624 CDS YP_096019.1 52842220 3078571 complement(2242539..2243372) 1 NC_002942.5 queuine tRNA-ribosyltransferase 2243372 tgt 3078571 tgt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 queuine tRNA-ribosyltransferase YP_096019.1 2242539 R 272624 CDS YP_096020.1 52842221 3078559 complement(2243419..2244468) 1 NC_002942.5 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 2244468 queA 3078559 queA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_096020.1 2243419 R 272624 CDS YP_096021.1 52842222 3078447 complement(2244549..2244962) 1 NC_002942.5 hypothetical protein 2244962 3078447 lpg2005 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096021.1 2244549 R 272624 CDS YP_096022.1 52842223 3077842 complement(2245044..2246900) 1 NC_002942.5 ABC transporter ATP-binding protein 2246900 uup-A 3077842 uup-A Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096022.1 2245044 R 272624 CDS YP_096023.1 52842224 3078673 complement(2246958..2247449) 1 NC_002942.5 aspartyl protease 2247449 3078673 lpg2007 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartyl protease YP_096023.1 2246958 R 272624 CDS YP_096024.1 52842225 3078701 complement(2247452..2247838) 1 NC_002942.5 endoribonuclease L-PSP 2247838 3078701 lpg2008 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endoribonuclease L-PSP YP_096024.1 2247452 R 272624 CDS YP_096025.1 52842226 3078596 complement(2247838..2249985) 1 NC_002942.5 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 2249985 spoT 3078596 spoT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase YP_096025.1 2247838 R 272624 CDS YP_096026.1 52842227 3078527 complement(2250383..2251012) 1 NC_002942.5 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2251012 gmk 3078527 gmk Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanylate kinase YP_096026.1 2250383 R 272624 CDS YP_096027.1 52842228 3078516 complement(2251018..2251884) 1 NC_002942.5 hypothetical protein 2251884 3078516 lpg2011 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096027.1 2251018 R 272624 CDS YP_096028.1 52842229 3078517 2252185..2252892 1 NC_002942.5 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 2252892 rph 3078517 rph Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease PH YP_096028.1 2252185 D 272624 CDS YP_096029.1 52842230 3078630 complement(2253222..2254256) 1 NC_002942.5 twitching motility protein PilT 2254256 pilT 3078630 pilT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 twitching motility protein PilT YP_096029.1 2253222 R 272624 CDS YP_096030.1 52842231 3078644 2254420..2255115 1 NC_002942.5 pyridoxal-5'-phosphate dependent enzyme family protein 2255115 3078644 lpg2014 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridoxal-5'-phosphate dependent enzyme family protein YP_096030.1 2254420 D 272624 CDS YP_096031.1 52842232 3078601 2255112..2255900 1 NC_002942.5 pyrroline-5-carboxylate reductase 2255900 proC 3078601 proC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyrroline-5-carboxylate reductase YP_096031.1 2255112 D 272624 CDS YP_096032.1 52842233 3078629 2256245..2256820 1 NC_002942.5 hypothetical protein 2256820 3078629 lpg2016 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096032.1 2256245 D 272624 CDS YP_096033.1 52842234 3078597 2256868..2257482 1 NC_002942.5 hypothetical protein 2257482 3078597 lpg2017 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096033.1 2256868 D 272624 CDS YP_096034.1 52842235 3078592 2257496..2257777 1 NC_002942.5 hypothetical protein 2257777 3078592 lpg2018 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096034.1 2257496 D 272624 CDS YP_096035.1 52842236 3078510 complement(2257930..2259618) 1 NC_002942.5 serine metalloprotease 2259618 3078510 lpg2019 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine metalloprotease YP_096035.1 2257930 R 272624 CDS YP_096036.1 52842237 3078574 complement(2259750..2260763) 1 NC_002942.5 transcriptional regulator OruR 2260763 oruR 3078574 oruR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator OruR YP_096036.1 2259750 R 272624 CDS YP_096037.1 52842238 3078499 complement(2260881..2262206) 1 NC_002942.5 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2262206 ahcY 3078499 ahcY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 S-adenosyl-L-homocysteine hydrolase YP_096037.1 2260881 R 272624 CDS YP_096038.1 52842239 3078505 complement(2262225..2263373) 1 NC_002942.5 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2263373 metK 3078505 metK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 S-adenosylmethionine synthetase YP_096038.1 2262225 R 272624 CDS YP_096039.1 52842240 3078598 complement(2263582..2264706) 1 NC_002942.5 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2264706 3078598 lpg2023 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbamoyl phosphate synthase small subunit YP_096039.1 2263582 R 272624 CDS YP_096040.1 52842241 3078697 complement(2264790..2265929) 1 NC_002942.5 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 2265929 dnaJ 3078697 dnaJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 molecular chaperone DnaJ YP_096040.1 2264790 R 272624 CDS YP_096041.1 52842242 3078702 complement(2266119..2268068) 1 NC_002942.5 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2268068 dnaK 3078702 dnaK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 molecular chaperone DnaK YP_096041.1 2266119 R 272624 CDS YP_096042.1 52842243 3078731 complement(2268198..2268800) 1 NC_002942.5 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2268800 grpE 3078731 grpE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heat shock protein GrpE YP_096042.1 2268198 R 272624 CDS YP_096043.1 52842244 3078735 2269077..2270414 1 NC_002942.5 2-keto-3-deoxy-D-arabino-heptulosonate 7- phosphate synthase 2270414 dhs1 3078735 dhs1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-keto-3-deoxy-D-arabino-heptulosonate 7- phosphate synthase YP_096043.1 2269077 D 272624 CDS YP_096044.1 52842245 3078741 complement(2270563..2271624) 1 NC_002942.5 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 2271624 hemE 3078741 hemE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uroporphyrinogen decarboxylase YP_096044.1 2270563 R 272624 CDS YP_096045.1 52842246 3078750 2271861..2272199 1 NC_002942.5 dihydroneopterin aldolase FolB, kinase 2272199 3078750 lpg2029 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydroneopterin aldolase FolB, kinase YP_096045.1 2271861 D 272624 CDS YP_096046.1 52842247 3078786 complement(2272239..2272937) 1 NC_002942.5 hypothetical protein 2272937 3078786 lpg2030 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096046.1 2272239 R 272624 CDS YP_096047.1 52842248 3078795 complement(2272934..2274703) 1 NC_002942.5 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2274703 argS 3078795 argS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arginyl-tRNA synthetase YP_096047.1 2272934 R 272624 CDS YP_096048.1 52842249 3078798 complement(2274807..2275943) 1 NC_002942.5 transporter permease 2275943 3078798 lpg2032 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transporter permease YP_096048.1 2274807 R 272624 CDS YP_096049.1 52842250 3078801 2276012..2278084 1 NC_002942.5 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2278084 recG 3078801 recG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent DNA helicase RecG YP_096049.1 2276012 D 272624 CDS YP_096050.1 52842251 3078817 2278577..2279740 1 NC_002942.5 cation efflux family protein 2279740 3078817 lpg2034 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation efflux family protein YP_096050.1 2278577 D 272624 CDS YP_096051.1 52842252 3078848 2279856..2280614 1 NC_002942.5 Zip family protein 2280614 3078848 lpg2035 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Zip family protein YP_096051.1 2279856 D 272624 CDS YP_096052.1 52842253 3078862 2280607..2281209 1 NC_002942.5 Maf-like protein (septum formation) 2281209 3078862 lpg2036 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Maf-like protein (septum formation) YP_096052.1 2280607 D 272624 CDS YP_096053.1 52842254 3078863 2281241..2282509 1 NC_002942.5 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2282509 eno 3078863 eno Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphopyruvate hydratase YP_096053.1 2281241 D 272624 CDS YP_096054.1 52842255 3078873 2282734..2283003 1 NC_002942.5 transmembrane protein 2283003 3078873 lpg2038 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096054.1 2282734 D 272624 CDS YP_096055.1 52842256 3078905 complement(2283016..2283897) 1 NC_002942.5 mevalonate kinase 2283897 3078905 lpg2039 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mevalonate kinase YP_096055.1 2283016 R 272624 CDS YP_096056.1 52842257 3078909 complement(2283884..2284852) 1 NC_002942.5 mevalonate diphosphate decarboxylase 2284852 3078909 lpg2040 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mevalonate diphosphate decarboxylase YP_096056.1 2283884 R 272624 CDS YP_096057.1 52842258 3078917 complement(2284849..2285502) 1 NC_002942.5 radical activating enzyme 2285502 3078917 lpg2041 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 radical activating enzyme YP_096057.1 2284849 R 272624 CDS YP_096058.1 52842259 3078930 complement(2285499..2286467) 1 NC_002942.5 hypothetical protein 2286467 3078930 lpg2042 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096058.1 2285499 R 272624 CDS YP_096059.1 52842260 3078946 complement(2286464..2286994) 1 NC_002942.5 peptidoglycan-associated lipoprotein (19 kDa surface antigen) (PPL) 2286994 3078946 lpg2043 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidoglycan-associated lipoprotein (19 kDa surface antigen) (PPL) YP_096059.1 2286464 R 272624 CDS YP_096060.1 52842261 3078961 complement(2287092..2287694) 1 NC_002942.5 hypothetical protein 2287694 3078961 lpg2044 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096060.1 2287092 R 272624 CDS YP_096061.1 52842262 3078975 complement(2287698..2288621) 1 NC_002942.5 ABC transporter substrate-binding protein 2288621 3078975 lpg2045 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter substrate-binding protein YP_096061.1 2287698 R 272624 CDS YP_096062.1 52842263 3078987 complement(2288651..2289388) 1 NC_002942.5 ABC transporter ATP-binding protein 2289388 3078987 lpg2046 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096062.1 2288651 R 272624 CDS YP_096063.1 52842264 3078994 complement(2289389..2290513) 1 NC_002942.5 ABC transporter permease 2290513 3078994 lpg2047 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_096063.1 2289389 R 272624 CDS YP_096064.1 52842265 3079037 2290607..2291458 1 NC_002942.5 hypothetical protein 2291458 3079037 lpg2048 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096064.1 2290607 D 272624 CDS YP_096065.1 52842266 3078967 2291585..2291884 1 NC_002942.5 hypothetical protein 2291884 3078967 lpg2049 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096065.1 2291585 D 272624 CDS YP_096066.1 52842267 3078780 complement(2292022..2293080) 1 NC_002942.5 hypothetical protein 2293080 3078780 lpg2050 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096066.1 2292022 R 272624 CDS YP_096067.1 52842268 3078803 2293248..2294276 1 NC_002942.5 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 2294276 3078803 lpg2051 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 isopentenyl pyrophosphate isomerase YP_096067.1 2293248 D 272624 CDS YP_096068.1 52842269 3078932 2294267..2295565 1 NC_002942.5 hydroxymethylglutaryl CoA reductase 2295565 3078932 lpg2052 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydroxymethylglutaryl CoA reductase YP_096068.1 2294267 D 272624 CDS YP_096069.1 52842270 3078613 2295562..2296440 1 NC_002942.5 hypothetical protein 2296440 3078613 lpg2053 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096069.1 2295562 D 272624 CDS YP_096070.1 52842271 3078821 complement(2296937..2297941) 1 NC_002942.5 prophage DLP12 integrase 2297941 intD 3078821 intD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prophage DLP12 integrase YP_096070.1 2296937 R 272624 CDS YP_096071.1 52842272 3078901 complement(2297854..2298156) 1 NC_002942.5 hypothetical protein 2298156 3078901 lpg2058 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096071.1 2297854 R 272624 CDS YP_096072.1 52842273 3079002 2298566..2299189 1 NC_002942.5 phage repressor 2299189 3079002 lpg2059 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phage repressor YP_096072.1 2298566 D 272624 CDS YP_096073.1 52842274 3078687 2299553..2300860 1 NC_002942.5 hypothetical protein 2300860 3078687 lpg2060 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096073.1 2299553 D 272624 CDS YP_096074.1 52842275 3078989 complement(2300843..2302048) 1 NC_002942.5 major facilitator family transporter 2302048 3078989 lpg2061 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_096074.1 2300843 R 272624 CDS YP_096075.1 52842276 3078823 complement(2302092..2302862) 1 NC_002942.5 methylase 2302862 3078823 lpg2062 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methylase YP_096075.1 2302092 R 272624 CDS YP_096076.1 52842277 3078869 2303373..2305139 1 NC_002942.5 ABC transporter ATP-binding protein 2305139 3078869 lpg2063 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096076.1 2303373 D 272624 CDS YP_096077.1 52842278 3078643 2305136..2306944 1 NC_002942.5 ATP-binding transmembrane ABC transporter 2306944 3078643 lpg2064 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-binding transmembrane ABC transporter YP_096077.1 2305136 D 272624 CDS YP_096078.1 52842279 3078765 2307026..2307868 1 NC_002942.5 D-xylose reductase III 2307868 3078765 lpg2065 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-xylose reductase III YP_096078.1 2307026 D 272624 CDS YP_096079.1 52842280 3078522 2307879..2308379 1 NC_002942.5 acetyltransferase 2308379 3078522 lpg2066 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_096079.1 2307879 D 272624 CDS YP_096080.1 52842281 3078554 2308402..2309184 1 NC_002942.5 hypothetical protein 2309184 3078554 lpg2067 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096080.1 2308402 D 272624 CDS YP_096081.1 52842282 3078723 2309199..2309576 1 NC_002942.5 nucleoside triphosphate pyrophosphohydrolase MazG 2309576 3078723 lpg2068 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleoside triphosphate pyrophosphohydrolase MazG YP_096081.1 2309199 D 272624 CDS YP_096082.1 52842283 3078934 2309882..2311333 1 NC_002942.5 transposase Tn5 2311333 3078934 lpg2069 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase Tn5 YP_096082.1 2309882 D 272624 CDS YP_096083.1 52842284 3078924 complement(2311404..2312924) 1 NC_002942.5 reverse transcriptase 2312924 3078924 lpg2070 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 reverse transcriptase YP_096083.1 2311404 R 272624 CDS YP_096084.1 52842285 3078745 2312884..2313354 1 NC_002942.5 hypothetical protein 2313354 3078745 lpg2071 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096084.1 2312884 D 272624 CDS YP_096085.1 52842286 3078610 2313772..2314146 1 NC_002942.5 hypothetical protein 2314146 3078610 lpg2072 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096085.1 2313772 D 272624 CDS YP_096086.1 52842287 3078774 complement(2314344..2315951) 1 NC_002942.5 hypothetical protein 2315951 3078774 lpg2073 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096086.1 2314344 R 272624 CDS YP_096087.1 52842288 3078605 complement(2315954..2316583) 1 NC_002942.5 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 2316583 3078605 lpg2074 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_096087.1 2315954 R 272624 CDS YP_096088.1 52842289 3078819 complement(2316456..2317292) 1 NC_002942.5 DNA adenine methylase 2317292 dam 3078819 dam Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA adenine methylase YP_096088.1 2316456 R 272624 CDS YP_096089.1 52842290 3079007 complement(2317885..2318976) 1 NC_002942.5 hypothetical protein 2318976 3079007 lpg2076 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096089.1 2317885 R 272624 CDS YP_096090.1 52842291 3078792 complement(2319208..2325153) 1 NC_002942.5 hypothetical protein 2325153 3078792 lpg2077 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096090.1 2319208 R 272624 CDS YP_096091.1 52842292 3078739 complement(2325174..2327066) 1 NC_002942.5 hypothetical protein 2327066 3078739 lpg2078 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096091.1 2325174 R 272624 CDS YP_096092.1 52842293 3078591 complement(2327599..2330328) 1 NC_002942.5 hypothetical protein 2330328 traG 3078591 traG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096092.1 2327599 R 272624 CDS YP_096093.1 52842294 3078831 complement(2330325..2331710) 1 NC_002942.5 hypothetical protein 2331710 traH 3078831 traH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096093.1 2330325 R 272624 CDS YP_096094.1 52842295 3078882 complement(2331707..2332129) 1 NC_002942.5 sex pilus assembly TraF, thiol-disulfide isomerase and thioredoxins 2332129 traF 3078882 traF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sex pilus assembly TraF, thiol-disulfide isomerase and thioredoxins YP_096094.1 2331707 R 272624 CDS YP_096095.1 52842296 3079011 complement(2332119..2332901) 1 NC_002942.5 pilus assembly protein TraF 2332901 traF 3079011 traF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pilus assembly protein TraF YP_096095.1 2332119 R 272624 CDS YP_096096.1 52842297 3078856 complement(2332894..2334705) 1 NC_002942.5 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer protein TraN 2334705 traN 3078856 traN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugal transfer protein TraN YP_096096.1 2332894 R 272624 CDS YP_096097.1 52842298 3078558 complement(2334705..2335376) 1 NC_002942.5 conjugative transfer protein TrbC 2335376 3078558 lpg2084 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative transfer protein TrbC YP_096097.1 2334705 R 272624 CDS YP_096098.1 52842299 3078748 complement(2335389..2336384) 1 NC_002942.5 hypothetical protein 2336384 traU 3078748 traU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096098.1 2335389 R 272624 CDS YP_096099.1 52842300 3078931 complement(2336381..2336989) 1 NC_002942.5 hypothetical protein 2336989 3078931 lpg2086 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096099.1 2336381 R 272624 CDS YP_096100.1 52842301 3078996 complement(2337314..2339911) 1 NC_002942.5 hypothetical protein 2339911 traC 3078996 traC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096100.1 2337314 R 272624 CDS YP_096101.1 52842302 3078616 complement(2339878..2340228) 1 NC_002942.5 conjugative transfer: assembly 2340228 traV 3078616 traV Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative transfer: assembly YP_096101.1 2339878 R 272624 CDS YP_096102.1 52842303 3079003 complement(2340242..2341561) 1 NC_002942.5 conjugative transfer protein TraB 2341561 3079003 lpg2089 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative transfer protein TraB YP_096102.1 2340242 R 272624 CDS YP_096103.1 52842304 3078969 complement(2341530..2342243) 1 NC_002942.5 conjugative transfer protein TraK 2342243 3078969 lpg2090 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative transfer protein TraK YP_096103.1 2341530 R 272624 CDS YP_096104.1 52842305 3078814 complement(2342246..2342809) 1 NC_002942.5 conjugative transfer protein TraE 2342809 3078814 lpg2091 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 conjugative transfer protein TraE YP_096104.1 2342246 R 272624 CDS YP_096105.1 52842306 3079000 complement(2342813..2343106) 1 NC_002942.5 sex pilus assembly protein-like 2343106 3079000 lpg2092 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sex pilus assembly protein-like YP_096105.1 2342813 R 272624 CDS YP_096106.1 52842307 3078991 complement(2343108..2343410) 1 NC_002942.5 fimbrial protein -like 2343410 3078991 lpg2093 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fimbrial protein -like YP_096106.1 2343108 R 272624 CDS YP_096107.1 52842308 3078838 complement(2343425..2343661) 1 NC_002942.5 carbon storage regulator RsmA 2343661 csrA 3078838 csrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbon storage regulator RsmA YP_096107.1 2343425 R 272624 CDS YP_096108.1 52842309 3077632 complement(2344000..2344884) 1 NC_002942.5 protein LvrA 2344884 lvrA 3077632 lvrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrA YP_096108.1 2344000 R 272624 CDS YP_096109.1 52842310 3078707 2345033..2345737 1 NC_002942.5 prophage repressor CI-like 2345737 3078707 lpg2096 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prophage repressor CI-like YP_096109.1 2345033 D 272624 CDS YP_096110.1 52842311 3078497 2345877..2346560 1 NC_002942.5 hypothetical protein 2346560 3078497 lpg2097 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096110.1 2345877 D 272624 CDS YP_096111.1 52842312 3078688 2347009..2347581 1 NC_002942.5 MsrA3 - peptide methionine sulfoxide reductase 2347581 3078688 lpg2098 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MsrA3 - peptide methionine sulfoxide reductase YP_096111.1 2347009 D 272624 CDS YP_096112.1 52842313 3079022 2347541..2348062 1 NC_002942.5 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2348062 3079022 lpg2099 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionine sulfoxide reductase B YP_096112.1 2347541 D 272624 CDS YP_096113.1 52842314 3078927 complement(2348055..2348642) 1 NC_002942.5 phosphatidoglycerophosphate synthase 2348642 3078927 lpg2100 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidoglycerophosphate synthase YP_096113.1 2348055 R 272624 CDS YP_096114.1 52842315 3078881 complement(2348647..2350782) 1 NC_002942.5 mercuric reductase 2350782 merA1 3078881 merA1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mercuric reductase YP_096114.1 2348647 R 272624 CDS YP_096115.1 52842316 3078990 complement(2350801..2351682) 1 NC_002942.5 sterol desaturase 2351682 3078990 lpg2102 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sterol desaturase YP_096115.1 2350801 R 272624 CDS YP_096116.1 52842317 3078868 complement(2351789..2351935) 1 NC_002942.5 hypothetical protein 2351935 3078868 lpg2103 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096116.1 2351789 R 272624 CDS YP_096117.1 52842318 3078769 2352127..2352303 1 NC_002942.5 hypothetical protein 2352303 3078769 lpg2104 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096117.1 2352127 D 272624 CDS YP_096118.1 52842319 3078797 complement(2352473..2352970) 1 NC_002942.5 transmembrane protein 2352970 3078797 lpg2105 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096118.1 2352473 R 272624 CDS YP_096119.1 52842320 3078900 complement(2352960..2353739) 1 NC_002942.5 hypothetical protein 2353739 3078900 lpg2106 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096119.1 2352960 R 272624 CDS YP_096120.1 52842321 3078836 complement(2353732..2354586) 1 NC_002942.5 hypothetical protein 2354586 3078836 lpg2107 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096120.1 2353732 R 272624 CDS YP_096121.1 52842322 3078877 complement(2354601..2354894) 1 NC_002942.5 hypothetical protein 2354894 3078877 lpg2108 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096121.1 2354601 R 272624 CDS YP_096122.1 52842323 3078837 complement(2355084..2355605) 1 NC_002942.5 hypothetical protein 2355605 3078837 lpg2109 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096122.1 2355084 R 272624 CDS YP_096123.1 52842324 3078871 complement(2355910..2356398) 1 NC_002942.5 hypothetical protein 2356398 3078871 lpg2110 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096123.1 2355910 R 272624 CDS YP_096124.1 52842325 3078916 complement(2357327..2357848) 1 NC_002942.5 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2357848 3078916 lpg2111 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionine sulfoxide reductase B YP_096124.1 2357327 R 272624 CDS YP_096125.1 52842326 3078915 2358020..2358574 1 NC_002942.5 24 kDa macrophage-induced major protein 2358574 3078915 lpg2112 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 24 kDa macrophage-induced major protein YP_096125.1 2358020 D 272624 CDS YP_096126.1 52842327 3078879 2359008..2359208 1 NC_002942.5 ATP dependent DNA helicase-like 2359208 recG 3078879 recG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP dependent DNA helicase-like YP_096126.1 2359008 D 272624 CDS YP_096127.1 52842328 3078872 2359302..2359685 1 NC_002942.5 transposase 2359685 3078872 lpg2114 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase YP_096127.1 2359302 D 272624 CDS YP_096128.1 52842329 3079029 complement(2359739..2360692) 1 NC_002942.5 phage AbiD protein 2360692 3079029 lpg2115 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phage AbiD protein YP_096128.1 2359739 R 272624 CDS YP_096129.1 52842330 3078738 2361172..2362620 1 NC_002942.5 IS4 family transposase TnpA 2362620 3078738 lpg2116 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS4 family transposase TnpA YP_096129.1 2361172 D 272624 CDS YP_096130.1 52842331 3078535 complement(2362653..2363828) 1 NC_002942.5 transposase TnpA 2363828 3078535 lpg2118 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase TnpA YP_096130.1 2362653 R 272624 CDS YP_096131.1 52842332 3078864 complement(2362653..2363213) 1 NC_002942.5 transposase, TnpA 2363213 3078864 lpg2117 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase, TnpA YP_096131.1 2362653 R 272624 CDS YP_096132.1 52842333 3078742 complement(2363881..2364906) 1 NC_002942.5 transposase (ISmav2) 2364906 3078742 lpg2119 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase (ISmav2) YP_096132.1 2363881 R 272624 CDS YP_096133.1 52842334 3079034 2365065..2366483 1 NC_002942.5 IS4 family transposase Tn5 2366483 3079034 lpg2120 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IS4 family transposase Tn5 YP_096133.1 2365065 D 272624 CDS YP_096134.1 52842335 3079031 2366711..2366920 1 NC_002942.5 cold shock DNA binding domain-containing protein 2366920 3079031 lpg2121 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock DNA binding domain-containing protein YP_096134.1 2366711 D 272624 CDS YP_096135.1 52842336 3079012 2367160..2368566 1 NC_002942.5 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 2368566 dbpA 3079012 dbpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent RNA helicase DbpA YP_096135.1 2367160 D 272624 CDS YP_096136.1 52842337 3078852 2368723..2369634 1 NC_002942.5 cobalt zinc cadmium cation transporter 2369634 3078852 lpg2123 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cobalt zinc cadmium cation transporter YP_096136.1 2368723 D 272624 CDS YP_096137.1 52842338 3078796 2369804..2369977 1 NC_002942.5 hypothetical protein 2369977 3078796 lpg2124 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096137.1 2369804 D 272624 CDS YP_096138.1 52842339 3078812 complement(2370145..2370606) 1 NC_002942.5 hypothetical protein 2370606 3078812 lpg2125 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096138.1 2370145 R 272624 CDS YP_096139.1 52842340 3078907 complement(2370656..2372533) 1 NC_002942.5 Kup system potassium uptake protein 2372533 kup2 3078907 kup2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Kup system potassium uptake protein YP_096139.1 2370656 R 272624 CDS YP_096140.1 52842341 3078685 2373011..2373499 1 NC_002942.5 hypothetical protein 2373499 3078685 lpg2127 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096140.1 2373011 D 272624 CDS YP_096141.1 52842342 3078753 complement(2373532..2374194) 1 NC_002942.5 hypothetical protein 2374194 3078753 lpg2128 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096141.1 2373532 R 272624 CDS YP_096142.1 52842343 3079019 complement(2374202..2374498) 1 NC_002942.5 hypothetical protein 2374498 3079019 lpg2129 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096142.1 2374202 R 272624 CDS YP_096143.1 52842344 3078883 2374428..2374697 1 NC_002942.5 hypothetical protein 2374697 3078883 lpg2130 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096143.1 2374428 D 272624 CDS YP_096144.1 52842345 3078870 complement(2374714..2375256) 1 NC_002942.5 conserved gene; node of Ranvier; ankyrin 3 2375256 legA6 3078870 legA6 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin 3 YP_096144.1 2374714 R 272624 CDS YP_096145.1 52842346 3078718 complement(2375275..2376813) 1 NC_002942.5 sensory box/GGDEF family protein 2376813 3078718 lpg2132 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box/GGDEF family protein YP_096145.1 2375275 R 272624 CDS YP_096146.1 52842347 3078618 2377025..2378293 1 NC_002942.5 proline/glycine betaine transporter-like protein 2378293 3078618 lpg2133 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proline/glycine betaine transporter-like protein YP_096146.1 2377025 D 272624 CDS YP_096147.1 52842348 3078727 complement(2378395..2381595) 1 NC_002942.5 chemiosmotic efflux system protein A 2381595 3078727 lpg2134 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system protein A YP_096147.1 2378395 R 272624 CDS YP_096148.1 52842349 3078725 complement(2381596..2382564) 1 NC_002942.5 chemiosmotic efflux system protein B 2382564 3078725 lpg2135 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system protein B YP_096148.1 2381596 R 272624 CDS YP_096149.1 52842350 3078816 complement(2382561..2383907) 1 NC_002942.5 chemiosmotic efflux system protein C 2383907 3078816 lpg2136 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chemiosmotic efflux system protein C YP_096149.1 2382561 R 272624 CDS YP_096150.1 52842351 3078887 complement(2384233..2385849) 1 NC_002942.5 conserved gene; Ser/Thr kinase; calmodulin-dependent protein kinase 2385849 legK2 3078887 legK2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 calmodulin-dependent protein kinase YP_096150.1 2384233 R 272624 CDS YP_096151.1 52842352 3079021 2386207..2387121 1 NC_002942.5 LysR family transcriptional regulator 2387121 3079021 lpg2138 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_096151.1 2386207 D 272624 CDS YP_096152.1 52842353 3078775 complement(2387133..2387723) 1 NC_002942.5 pyridoxamine 5'-phosphate oxidase 2387723 3078775 lpg2139 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyridoxamine 5'-phosphate oxidase YP_096152.1 2387133 R 272624 CDS YP_096153.1 52842354 3078675 complement(2387854..2388234) 1 NC_002942.5 MarR family transcriptional regulator 2388234 3078675 lpg2140 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MarR family transcriptional regulator YP_096153.1 2387854 R 272624 CDS YP_096154.1 52842355 3078790 2388257..2389093 1 NC_002942.5 glucose-1-dehydrogenase 2389093 3078790 lpg2141 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucose-1-dehydrogenase YP_096154.1 2388257 D 272624 CDS YP_096155.1 52842356 3078660 2389116..2389376 1 NC_002942.5 hypothetical protein 2389376 3078660 lpg2142 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096155.1 2389116 D 272624 CDS YP_096156.1 52842357 3078681 complement(2389471..2390412) 1 NC_002942.5 hypothetical protein 2390412 3078681 lpg2143 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096156.1 2389471 R 272624 CDS YP_096157.1 52842358 3078487 2390645..2391163 1 NC_002942.5 conserved gene; contains ankyrin repeats; F-box protein 2391163 legAU13 3078487 legAU13 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 F-box protein YP_096157.1 2390645 D 272624 CDS YP_096158.1 52842359 3078850 complement(2391194..2391550) 1 NC_002942.5 two component response regulator protein 2391550 3078850 lpg2145 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component response regulator protein YP_096158.1 2391194 R 272624 CDS YP_096159.1 52842360 3078751 complement(2391603..2394053) 1 NC_002942.5 response regulator TutC 2394053 3078751 lpg2146 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 response regulator TutC YP_096159.1 2391603 R 272624 CDS YP_096160.1 52842361 3078602 2394467..2395915 1 NC_002942.5 hypothetical protein 2395915 3078602 lpg2147 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096160.1 2394467 D 272624 CDS YP_096161.1 52842362 3078874 2395991..2397271 1 NC_002942.5 hypothetical protein 2397271 3078874 lpg2148 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096161.1 2395991 D 272624 CDS YP_096162.1 52842363 3078693 2397359..2397718 1 NC_002942.5 hypothetical protein 2397718 3078693 lpg2149 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096162.1 2397359 D 272624 CDS YP_096163.1 52842364 3078894 2397952..2398533 1 NC_002942.5 hypothetical protein 2398533 3078894 lpg2150 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096163.1 2397952 D 272624 CDS YP_096164.1 52842365 3079184 2398592..2399458 1 NC_002942.5 aminoglycoside 6-adenylyltransferase 2399458 3079184 lpg2151 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminoglycoside 6-adenylyltransferase YP_096164.1 2398592 D 272624 CDS YP_096165.1 52842366 3078608 2399558..2401387 1 NC_002942.5 multidrug resistance ABC transporter ATP-binding protein 2401387 abcT3 3078608 abcT3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance ABC transporter ATP-binding protein YP_096165.1 2399558 D 272624 CDS YP_096166.1 52842367 3078682 2401678..2406279 1 NC_002942.5 SdeC, SdeB, AliA, SdeA, SdeD-like; Sid related protein-like 2406279 3078682 lpg2153 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Sid related protein-like YP_096166.1 2401678 D 272624 CDS YP_096167.1 52842368 3078935 2406709..2407614 1 NC_002942.5 SdeC, SdeB, AliA, SdeA, SdeD-like; Sid related protein-like 2407614 3078935 lpg2154 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Sid related protein-like YP_096167.1 2406709 D 272624 CDS YP_096168.1 52842369 3078981 2407667..2410288 1 NC_002942.5 hypothetical protein 2410288 3078981 lpg2155 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096168.1 2407667 D 272624 CDS YP_096169.1 52842370 3078822 2410554..2416334 1 NC_002942.5 SdeC, SdeB, SdeA, SidE, AliA-like; Sid related protein-like 2416334 3078822 lpg2156 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Sid related protein-like YP_096169.1 2410554 D 272624 CDS YP_096170.1 52842371 3078897 2416693..2421213 1 NC_002942.5 SidE, SdeA, SdeB, SdeC, AliA, SdeD-like; Sid related protein-like 2421213 3078897 lpg2157 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Sid related protein-like YP_096170.1 2416693 D 272624 CDS YP_096171.1 52842372 3078764 2421627..2422256 1 NC_002942.5 hypothetical protein 2422256 pmtA 3078764 pmtA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096171.1 2421627 D 272624 CDS YP_096172.1 52842373 3078766 complement(2422285..2423406) 1 NC_002942.5 hydroxyneurosporene (C20) methyltransferase CrtF 2423406 3078766 lpg2159 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydroxyneurosporene (C20) methyltransferase CrtF YP_096172.1 2422285 R 272624 CDS YP_096173.1 52842374 3078937 complement(2423699..2425147) 1 NC_002942.5 hypothetical protein 2425147 3078937 lpg2160 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096173.1 2423699 R 272624 CDS YP_096174.1 52842375 3078998 2425676..2427934 1 NC_002942.5 hypothetical protein 2427934 3078998 lpg2161 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096174.1 2425676 D 272624 CDS YP_096175.1 52842376 3078815 2428294..2428959 1 NC_002942.5 hypothetical protein 2428959 3078815 lpg2162 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096175.1 2428294 D 272624 CDS YP_096176.1 52842377 3078859 complement(2429231..2430076) 1 NC_002942.5 AraC family transcriptional regulator 2430076 3078859 lpg2163 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AraC family transcriptional regulator YP_096176.1 2429231 R 272624 CDS YP_096177.1 52842378 3078647 complement(2430292..2430756) 1 NC_002942.5 hypothetical protein 2430756 3078647 lpg2164 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096177.1 2430292 R 272624 CDS YP_096178.1 52842379 3078813 2430958..2431470 1 NC_002942.5 hypothetical protein 2431470 3078813 lpg2165 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096178.1 2430958 D 272624 CDS YP_096179.1 52842380 3078690 2431605..2432864 1 NC_002942.5 hypothetical protein 2432864 3078690 lpg2166 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096179.1 2431605 D 272624 CDS YP_096180.1 52842381 3079006 complement(2433024..2433728) 1 NC_002942.5 DeoR family transcriptional regulator 2433728 3079006 lpg2167 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DeoR family transcriptional regulator YP_096180.1 2433024 R 272624 CDS YP_096181.1 52842382 3078926 complement(2433697..2434470) 1 NC_002942.5 acetyltransferase 2434470 3078926 lpg2168 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_096181.1 2433697 R 272624 CDS YP_096182.1 52842383 3078794 2434660..2435034 1 NC_002942.5 hypothetical protein 2435034 3078794 lpg2169 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096182.1 2434660 D 272624 CDS YP_096183.1 52842384 3078808 2435166..2435807 1 NC_002942.5 hypothetical protein 2435807 3078808 lpg2170 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096183.1 2435166 D 272624 CDS YP_096184.1 52842385 3078671 2436055..2437065 1 NC_002942.5 hypothetical protein 2437065 3078671 lpg2171 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096184.1 2436055 D 272624 CDS YP_096185.1 52842386 3078999 complement(2437187..2438290) 1 NC_002942.5 adenosylhomocysteinase 2438290 3078999 lpg2172 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 adenosylhomocysteinase YP_096185.1 2437187 R 272624 CDS YP_096186.1 52842387 3078997 2438461..2439636 1 NC_002942.5 TnpA transposase 2439636 3078997 lpg2173 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 TnpA transposase YP_096186.1 2438461 D 272624 CDS YP_096187.1 52842388 3079016 2439943..2440710 1 NC_002942.5 (2-pyrone-4,6-)dicarboxylic acid hydrolase 2440710 3079016 lpg2175 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (2-pyrone-4,6-)dicarboxylic acid hydrolase YP_096187.1 2439943 D 272624 CDS YP_096188.1 52842389 3078567 complement(2440714..2442540) 1 NC_002942.5 sphingosine-1-phosphate lyase I 2442540 legS2 3078567 legS2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sphingosine-1-phosphate lyase I YP_096188.1 2440714 R 272624 CDS YP_096189.1 52842390 3078676 2442757..2443863 1 NC_002942.5 HlyD family secretion protein 2443863 3078676 lpg2177 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HlyD family secretion protein YP_096189.1 2442757 D 272624 CDS YP_096190.1 52842391 3078952 2443964..2447119 1 NC_002942.5 multidrug-efflux system transmembrane protein 2447119 mexF2 3078952 mexF2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug-efflux system transmembrane protein YP_096190.1 2443964 D 272624 CDS YP_096191.1 52842392 3079010 2447235..2451596 1 NC_002942.5 peptide synthetase, non-ribosomal 2451596 3079010 lpg2179 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide synthetase, non-ribosomal YP_096191.1 2447235 D 272624 CDS YP_096192.1 52842393 3078923 2451717..2454203 1 NC_002942.5 sensory box histidine kinase/response regulator 2454203 3078923 lpg2180 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box histidine kinase/response regulator YP_096192.1 2451717 D 272624 CDS YP_096193.1 52842394 3078632 2454375..2455283 1 NC_002942.5 sensory box sensor histidine kinase/response regulator 2455283 3078632 lpg2181 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box sensor histidine kinase/response regulator YP_096193.1 2454375 D 272624 CDS YP_096194.1 52842395 3078680 2455547..2456326 1 NC_002942.5 hypothetical protein 2456326 3078680 lpg2182 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096194.1 2455547 D 272624 CDS YP_096195.1 52842396 3078575 2456333..2457385 1 NC_002942.5 regulatory protein, SyrP-like 2457385 3078575 lpg2183 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 regulatory protein, SyrP-like YP_096195.1 2456333 D 272624 CDS YP_096196.1 52842397 3078677 complement(2457486..2458892) 1 NC_002942.5 hypothetical protein 2458892 3078677 lpg2184 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096196.1 2457486 R 272624 CDS YP_096197.1 52842398 3078865 complement(2458829..2459137) 1 NC_002942.5 hypothetical protein 2459137 3078865 lpg2185 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096197.1 2458829 R 272624 CDS YP_096198.1 52842399 3078670 2459143..2470485 1 NC_002942.5 polyketide synthase 2470485 pksJ 3078670 pksJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polyketide synthase YP_096198.1 2459143 D 272624 CDS YP_096199.1 52842400 3078683 complement(2470488..2470889) 1 NC_002942.5 hypothetical protein 2470889 3078683 lpg2187 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096199.1 2470488 R 272624 CDS YP_096200.1 52842401 3078833 2470888..2471040 1 NC_002942.5 hypothetical protein 2471040 3078833 lpg2188 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096200.1 2470888 D 272624 CDS YP_096201.1 52842402 3078993 complement(2471119..2472072) 1 NC_002942.5 drug efflux protein 2472072 ygjT 3078993 ygjT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 drug efflux protein YP_096201.1 2471119 R 272624 CDS YP_096202.1 52842403 3078941 complement(2472187..2474049) 1 NC_002942.5 IcmL-like protein 2474049 3078941 lpg2190 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 IcmL-like protein YP_096202.1 2472187 R 272624 CDS YP_096203.1 52842404 3078849 2474359..2474886 1 NC_002942.5 global stress protein GspA 2474886 ibpA 3078849 ibpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 global stress protein GspA YP_096203.1 2474359 D 272624 CDS YP_096204.1 52842405 3078960 2475025..2475591 1 NC_002942.5 small HspC2 heat shock protein 2475591 3078960 lpg2192 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 small HspC2 heat shock protein YP_096204.1 2475025 D 272624 CDS YP_096205.1 52842406 3078636 2475808..2477361 1 NC_002942.5 sulfate transporter 2477361 3078636 lpg2193 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfate transporter YP_096205.1 2475808 D 272624 CDS YP_096206.1 52842407 3078962 2477365..2477991 1 NC_002942.5 (beta)-carbonic anhydrase 2477991 3078962 lpg2194 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (beta)-carbonic anhydrase YP_096206.1 2477365 D 272624 CDS YP_096207.1 52842408 3078666 complement(2478104..2478400) 1 NC_002942.5 hypothetical protein 2478400 3078666 lpg2195 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096207.1 2478104 R 272624 CDS YP_096208.1 52842409 3078906 complement(2478431..2479402) 1 NC_002942.5 ornithine cyclodeaminase 2479402 3078906 lpg2196 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ornithine cyclodeaminase YP_096208.1 2478431 R 272624 CDS YP_096209.1 52842410 3078918 complement(2479457..2479804) 1 NC_002942.5 ketosteroid isomerase 2479804 3078918 lpg2197 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ketosteroid isomerase YP_096209.1 2479457 R 272624 CDS YP_096210.1 52842411 3078820 2480322..2481827 1 NC_002942.5 POT family peptide transport protein 2481827 3078820 lpg2198 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 POT family peptide transport protein YP_096210.1 2480322 D 272624 CDS YP_096211.1 52842412 3078668 complement(2481832..2482464) 1 NC_002942.5 hypothetical protein 2482464 3078668 lpg2199 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096211.1 2481832 R 272624 CDS YP_096212.1 52842413 3079004 complement(2482630..2483166) 1 NC_002942.5 hypothetical protein 2483166 3079004 lpg2200 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096212.1 2482630 R 272624 CDS YP_096213.1 52842414 3078970 complement(2483299..2484732) 1 NC_002942.5 replication factor C subunit (activator I) 2484732 3078970 lpg2201 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 replication factor C subunit (activator I) YP_096213.1 2483299 R 272624 CDS YP_096214.1 52842415 3078508 complement(2484763..2485095) 1 NC_002942.5 hypothetical protein 2485095 3078508 lpg2202 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096214.1 2484763 R 272624 CDS YP_096215.1 52842416 3078662 complement(2485291..2486850) 1 NC_002942.5 alginate O-acetylation protein AlgJ 2486850 3078662 lpg2203 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alginate O-acetylation protein AlgJ YP_096215.1 2485291 R 272624 CDS YP_096216.1 52842417 3078528 complement(2486847..2488268) 1 NC_002942.5 alginate O-acetylation protein 2488268 3078528 lpg2204 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alginate O-acetylation protein YP_096216.1 2486847 R 272624 CDS YP_096217.1 52842418 3079023 2488484..2489122 1 NC_002942.5 hypothetical protein 2489122 3079023 lpg2205 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096217.1 2488484 D 272624 CDS YP_096218.1 52842419 3078985 2489349..2490449 1 NC_002942.5 hypothetical protein 2490449 3078985 lpg2206 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096218.1 2489349 D 272624 CDS YP_096219.1 52842420 3078793 complement(2490497..2491720) 1 NC_002942.5 hypothetical protein 2491720 3078793 lpg2207 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096219.1 2490497 R 272624 CDS YP_096220.1 52842421 3078854 complement(2492063..2493076) 1 NC_002942.5 zinc binding dehydrogenase 2493076 3078854 lpg2208 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc binding dehydrogenase YP_096220.1 2492063 R 272624 CDS YP_096221.1 52842422 3078886 2493393..2493923 1 NC_002942.5 hypothetical protein 2493923 3078886 lpg2209 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096221.1 2493393 D 272624 CDS YP_096222.1 52842423 3078721 complement(2494084..2495133) 1 NC_002942.5 hypothetical protein 2495133 3078721 lpg2210 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096222.1 2494084 R 272624 CDS YP_096223.1 52842424 3078936 complement(2495267..2495671) 1 NC_002942.5 hypothetical protein 2495671 3078936 lpg2211 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096223.1 2495267 R 272624 CDS YP_096224.1 52842425 3078733 2495865..2497145 1 NC_002942.5 acetylpolyamine aminohydolase 2497145 bcp 3078733 bcp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetylpolyamine aminohydolase YP_096224.1 2495865 D 272624 CDS YP_096225.1 52842426 3078912 2497386..2497838 1 NC_002942.5 hemin binding protein Hbp 2497838 3078912 lpg2213 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hemin binding protein Hbp YP_096225.1 2497386 D 272624 CDS YP_096226.1 52842427 3078650 complement(2497935..2498858) 1 NC_002942.5 nucleoside-diphosphate sugar epimerase 2498858 3078650 lpg2214 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleoside-diphosphate sugar epimerase YP_096226.1 2497935 R 272624 CDS YP_096227.1 52842428 3078649 complement(2498937..2500532) 1 NC_002942.5 G431002C21 gene product; ankyrin repeat-containing protein 2500532 legA2 3078649 legA2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096227.1 2498937 R 272624 CDS YP_096228.1 52842429 3078965 complement(2500553..2502325) 1 NC_002942.5 purine NTPase 2502325 3078965 lpg2216 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 purine NTPase YP_096228.1 2500553 R 272624 CDS YP_096229.1 52842430 3078633 complement(2502575..2503549) 1 NC_002942.5 chitinase 2503549 3078633 lpg2217 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chitinase YP_096229.1 2502575 R 272624 CDS YP_096230.1 52842431 3078732 2503751..2504842 1 NC_002942.5 choline monooxygenase 2504842 3078732 lpg2218 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 choline monooxygenase YP_096230.1 2503751 D 272624 CDS YP_096231.1 52842432 3078728 2504988..2506124 1 NC_002942.5 hypothetical protein 2506124 3078728 lpg2219 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096231.1 2504988 D 272624 CDS YP_096232.1 52842433 3079036 complement(2506190..2507689) 1 NC_002942.5 hypothetical protein 2507689 3079036 lpg2220 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096232.1 2506190 R 272624 CDS YP_096233.1 52842434 3078772 complement(2507832..2508551) 1 NC_002942.5 hypothetical protein 2508551 3078772 lpg2221 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096233.1 2507832 R 272624 CDS YP_096234.1 52842435 3078730 complement(2508818..2509945) 1 NC_002942.5 hypothetical protein 2509945 3078730 lpg2222 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096234.1 2508818 R 272624 CDS YP_096235.1 52842436 3078746 complement(2510199..2511422) 1 NC_002942.5 hypothetical protein 2511422 3078746 lpg2223 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096235.1 2510199 R 272624 CDS YP_096236.1 52842437 3078518 2512062..2513843 1 NC_002942.5 UVB-resistance protein UVR8 2513843 3078518 lpg2224 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UVB-resistance protein UVR8 YP_096236.1 2512062 D 272624 CDS YP_096237.1 52842438 3078740 complement(2514038..2515567) 1 NC_002942.5 hypothetical protein 2515567 3078740 lpg2225 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096237.1 2514038 R 272624 CDS YP_096238.1 52842439 3078756 complement(2515574..2517265) 1 NC_002942.5 isovaleryl CoA dehydrogenase 2517265 3078756 lpg2226 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 isovaleryl CoA dehydrogenase YP_096238.1 2515574 R 272624 CDS YP_096239.1 52842440 3078691 complement(2517274..2518713) 1 NC_002942.5 acetyl CoA carboxylase subunit alpha 2518713 3078691 lpg2227 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyl CoA carboxylase subunit alpha YP_096239.1 2517274 R 272624 CDS YP_096240.1 52842441 3078959 2518922..2519983 1 NC_002942.5 3-oxoacyl-ACP synthase 2519983 3078959 lpg2228 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_096240.1 2518922 D 272624 CDS YP_096241.1 52842442 3079015 2519995..2521740 1 NC_002942.5 saframycin Mx1 synthetase B 2521740 3079015 lpg2229 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 saframycin Mx1 synthetase B YP_096241.1 2519995 D 272624 CDS YP_096242.1 52842443 3078526 2521730..2523124 1 NC_002942.5 acyl CoA ligase 2523124 3078526 lpg2230 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl CoA ligase YP_096242.1 2521730 D 272624 CDS YP_096243.1 52842444 3078947 2523344..2524096 1 NC_002942.5 3-oxoacyl-ACP reductase 2524096 fabG 3078947 fabG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP reductase YP_096243.1 2523344 D 272624 CDS YP_096244.1 52842445 3078828 2524093..2525103 1 NC_002942.5 3-oxoacyl-ACP synthase 2525103 fabH 3078828 fabH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-oxoacyl-ACP synthase YP_096244.1 2524093 D 272624 CDS YP_096245.1 52842446 3078761 complement(2525446..2525673) 1 NC_002942.5 acyl carrier protein 2525673 3078761 lpg2233 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl carrier protein YP_096245.1 2525446 R 272624 CDS YP_096246.1 52842447 3078884 complement(2525683..2527050) 1 NC_002942.5 multidrug resistance protein D 2527050 3078884 lpg2234 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance protein D YP_096246.1 2525683 R 272624 CDS YP_096247.1 52842448 3078885 2527060..2528262 1 NC_002942.5 sterol desaturase 2528262 3078885 lpg2235 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sterol desaturase YP_096247.1 2527060 D 272624 CDS YP_096248.1 52842449 3078843 2528349..2530757 1 NC_002942.5 nitric oxide reductase subunit B 2530757 3078843 lpg2236 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitric oxide reductase subunit B YP_096248.1 2528349 D 272624 CDS YP_096249.1 52842450 3079033 complement(2530946..2532784) 1 NC_002942.5 multidrug ABC transporter ATP-binding protein 2532784 abcT3 3079033 abcT3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug ABC transporter ATP-binding protein YP_096249.1 2530946 R 272624 CDS YP_096250.1 52842451 3078587 complement(2532943..2533329) 1 NC_002942.5 transmembrane protein 2533329 3078587 lpg2238 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096250.1 2532943 R 272624 CDS YP_096251.1 52842452 3078971 2533540..2537397 1 NC_002942.5 hypothetical protein 2537397 3078971 lpg2239 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096251.1 2533540 D 272624 CDS YP_096252.1 52842453 3078785 2537623..2538831 1 NC_002942.5 dipeptidyl aminopeptidase/acylaminoacyl peptidase 2538831 3078785 lpg2240 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dipeptidyl aminopeptidase/acylaminoacyl peptidase YP_096252.1 2537623 D 272624 CDS YP_096253.1 52842454 3078876 2538893..2540185 1 NC_002942.5 hypothetical protein 2540185 3078876 lpg2241 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096253.1 2538893 D 272624 CDS YP_096254.1 52842455 3078988 2540094..2541419 1 NC_002942.5 hypothetical protein 2541419 3078988 lpg2242 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096254.1 2540094 D 272624 CDS YP_096255.1 52842456 3078866 2541432..2542076 1 NC_002942.5 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2542076 upp 3078866 upp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uracil phosphoribosyltransferase YP_096255.1 2541432 D 272624 CDS YP_096256.1 52842457 3078734 2542341..2545283 1 NC_002942.5 hypothetical protein 2545283 3078734 lpg2244 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096256.1 2542341 D 272624 CDS YP_096257.1 52842458 3078948 complement(2545546..2546838) 1 NC_002942.5 C4-dicarboxylate transport protein 2546838 dctA 3078948 dctA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 C4-dicarboxylate transport protein YP_096257.1 2545546 R 272624 CDS YP_096258.1 52842459 3078491 complement(2547160..2547669) 1 NC_002942.5 hypothetical protein 2547669 3078491 lpg2246 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096258.1 2547160 R 272624 CDS YP_096259.1 52842460 3078902 2548037..2548792 1 NC_002942.5 DedA family protein 2548792 3078902 lpg2247 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DedA family protein YP_096259.1 2548037 D 272624 CDS YP_096260.1 52842461 3078700 complement(2549049..2551283) 1 NC_002942.5 hypothetical protein 2551283 3078700 lpg2248 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096260.1 2549049 R 272624 CDS YP_096261.1 52842462 3078586 complement(2551374..2552072) 1 NC_002942.5 glutamine amidotransferase 2552072 3078586 lpg2249 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine amidotransferase YP_096261.1 2551374 R 272624 CDS YP_096262.1 52842463 3078954 complement(2552202..2553362) 1 NC_002942.5 alcohol dehydrogenase 2553362 3078954 lpg2250 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alcohol dehydrogenase YP_096262.1 2552202 R 272624 CDS YP_096263.1 52842464 3079065 complement(2553492..2554889) 1 NC_002942.5 succinate semialdehyde dehydrogenase 2554889 3079065 lpg2251 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 succinate semialdehyde dehydrogenase YP_096263.1 2553492 R 272624 CDS YP_096264.1 52842465 3078973 complement(2554927..2556300) 1 NC_002942.5 glutamine synthetase 2556300 3078973 lpg2252 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine synthetase YP_096264.1 2554927 R 272624 CDS YP_096265.1 52842466 3078788 complement(2556352..2557140) 1 NC_002942.5 hypothetical protein 2557140 3078788 lpg2253 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096265.1 2556352 R 272624 CDS YP_096266.1 52842467 3078942 complement(2557137..2558033) 1 NC_002942.5 hypothetical protein 2558033 3078942 lpg2254 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096266.1 2557137 R 272624 CDS YP_096267.1 52842468 3079047 complement(2558082..2558333) 1 NC_002942.5 hypothetical protein 2558333 3079047 lpg2255 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096267.1 2558082 R 272624 CDS YP_096268.1 52842469 3078810 complement(2558698..2560116) 1 NC_002942.5 metallo-beta-lactamase superfamily protein 2560116 3078810 lpg2256 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metallo-beta-lactamase superfamily protein YP_096268.1 2558698 R 272624 CDS YP_096269.1 52842470 3078736 complement(2560179..2560829) 1 NC_002942.5 hypothetical protein 2560829 3078736 lpg2257 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096269.1 2560179 R 272624 CDS YP_096270.1 52842471 3078659 2560946..2561236 1 NC_002942.5 hypothetical protein 2561236 3078659 lpg2258 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096270.1 2560946 D 272624 CDS YP_096271.1 52842472 3078953 complement(2561327..2561638) 1 NC_002942.5 periplasmic, osmotically inducible protein Y-like 2561638 osmY 3078953 osmY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 periplasmic, osmotically inducible protein Y-like YP_096271.1 2561327 R 272624 CDS YP_096272.1 52842473 3079014 2561792..2563642 1 NC_002942.5 PHA synthase 2563642 phbC 3079014 phbC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 PHA synthase YP_096272.1 2561792 D 272624 CDS YP_096273.1 52842474 3078842 2563654..2565060 1 NC_002942.5 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase 2565060 3078842 lpg2261 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase YP_096273.1 2563654 D 272624 CDS YP_096274.1 52842475 3078896 2565057..2566175 1 NC_002942.5 acetate kinase 2566175 ackA2 3078896 ackA2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetate kinase YP_096274.1 2565057 D 272624 CDS YP_096275.1 52842476 3079064 2566215..2567105 1 NC_002942.5 curved DNA binding protein DnaJ 2567105 cbpA 3079064 cbpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 curved DNA binding protein DnaJ YP_096275.1 2566215 D 272624 CDS YP_096276.1 52842477 3078669 2567108..2567422 1 NC_002942.5 hypothetical protein 2567422 3078669 lpg2264 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096276.1 2567108 D 272624 CDS YP_096277.1 52842478 3078841 complement(2567419..2567982) 1 NC_002942.5 acyltransferase 2567982 3078841 lpg2265 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyltransferase YP_096277.1 2567419 R 272624 CDS YP_096278.1 52842479 3079041 2568100..2568651 1 NC_002942.5 hypothetical protein 2568651 3079041 lpg2266 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096278.1 2568100 D 272624 CDS YP_096279.1 52842480 3079057 complement(2568684..2569922) 1 NC_002942.5 prolidase 2569922 3079057 lpg2267 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prolidase YP_096279.1 2568684 R 272624 CDS YP_096280.1 52842481 3078919 2570220..2570831 1 NC_002942.5 hypothetical protein 2570831 3078919 lpg2268 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096280.1 2570220 D 272624 CDS YP_096281.1 52842482 3078712 2570779..2573355 1 NC_002942.5 endonuclease 2573355 3078712 lpg2269 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endonuclease YP_096281.1 2570779 D 272624 CDS YP_096282.1 52842483 3078706 2573383..2574225 1 NC_002942.5 oxidoreductase 2574225 3078706 lpg2270 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase YP_096282.1 2573383 D 272624 CDS YP_096283.1 52842484 3078686 2574377..2575027 1 NC_002942.5 hypothetical protein 2575027 3078686 lpg2271 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096283.1 2574377 D 272624 CDS YP_096284.1 52842485 3079092 complement(2575202..2575693) 1 NC_002942.5 transmembrane protein 2575693 3079092 lpg2272 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096284.1 2575202 R 272624 CDS YP_096285.1 52842486 3079120 complement(2575835..2577148) 1 NC_002942.5 glycerol-3-phosphate ABC transporter substrate-binding protein 2577148 ugpB 3079120 ugpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerol-3-phosphate ABC transporter substrate-binding protein YP_096285.1 2575835 R 272624 CDS YP_096286.1 52842487 3079131 complement(2577145..2577864) 1 NC_002942.5 glycerophosphoryl diester esterase 2577864 ugpQ 3079131 ugpQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerophosphoryl diester esterase YP_096286.1 2577145 R 272624 CDS YP_096287.1 52842488 3079140 complement(2577869..2578576) 1 NC_002942.5 hypothetical protein 2578576 3079140 lpg2275 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096287.1 2577869 R 272624 CDS YP_096288.1 52842489 3079157 2578877..2579950 1 NC_002942.5 Glu/Leu/Phe/Val dehydrogenase 2579950 3079157 lpg2276 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Glu/Leu/Phe/Val dehydrogenase YP_096288.1 2578877 D 272624 CDS YP_096289.1 52842490 3079162 2579965..2580621 1 NC_002942.5 O-methyltransferase, SAM-dependent 2580621 3079162 lpg2277 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-methyltransferase, SAM-dependent YP_096289.1 2579965 D 272624 CDS YP_096290.1 52842491 3079183 2580649..2581734 1 NC_002942.5 4-hydroxyphenylpyruvate dioxygenase 2581734 hpd 3079183 hpd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-hydroxyphenylpyruvate dioxygenase YP_096290.1 2580649 D 272624 CDS YP_096291.1 52842492 3079196 2581790..2582788 1 NC_002942.5 fumarylacetoacetate hydrolase 2582788 3079196 lpg2279 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fumarylacetoacetate hydrolase YP_096291.1 2581790 D 272624 CDS YP_096292.1 52842493 3079204 2582785..2583423 1 NC_002942.5 glutathione S-transferase 2583423 3079204 lpg2280 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione S-transferase YP_096292.1 2582785 D 272624 CDS YP_096293.1 52842494 3079209 complement(2583420..2583980) 1 NC_002942.5 hypothetical protein 2583980 3079209 lpg2281 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096293.1 2583420 R 272624 CDS YP_096294.2 161723246 3079220 2584128..2585531 1 NC_002942.5 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2585531 asnC 3079220 asnC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 asparaginyl-tRNA synthetase YP_096294.2 2584128 D 272624 CDS YP_096295.1 52842496 3079226 complement(2585528..2585926) 1 NC_002942.5 hypothetical protein 2585926 3079226 lpg2283 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096295.1 2585528 R 272624 CDS YP_096296.1 52842497 3079244 complement(2585950..2586633) 1 NC_002942.5 ABC transporter ATP-binding protein 2586633 3079244 lpg2284 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096296.1 2585950 R 272624 CDS YP_096297.1 52842498 3079254 complement(2586626..2587981) 1 NC_002942.5 lipoprotein ABC transporter 2587981 3079254 lpg2285 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein ABC transporter YP_096297.1 2586626 R 272624 CDS YP_096298.1 52842499 3079264 complement(2588112..2589086) 1 NC_002942.5 pirin 2589086 3079264 lpg2286 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pirin YP_096298.1 2588112 R 272624 CDS YP_096299.1 52842500 3079269 complement(2589004..2589624) 1 NC_002942.5 ACP phosphodiesterase 2589624 acpD 3079269 acpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ACP phosphodiesterase YP_096299.1 2589004 R 272624 CDS YP_096300.1 52842501 3079272 2589773..2590693 1 NC_002942.5 LysR family transcriptional regulator 2590693 3079272 lpg2288 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_096300.1 2589773 D 272624 CDS YP_096301.1 52842502 3079273 complement(2590658..2590885) 1 NC_002942.5 hypothetical protein 2590885 3079273 lpg2289 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096301.1 2590658 R 272624 CDS YP_096302.1 52842503 3079325 complement(2591078..2591641) 1 NC_002942.5 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2591641 pgsA 3079325 pgsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_096302.1 2591078 R 272624 CDS YP_096303.1 52842504 3079327 complement(2591661..2592320) 1 NC_002942.5 HAD superfamily hydrolase 2592320 3079327 lpg2294 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HAD superfamily hydrolase YP_096303.1 2591661 R 272624 CDS YP_096304.1 52842505 3079332 complement(2592313..2593266) 1 NC_002942.5 ribosomal large subunit (23S rRNA) pseudouridine synthase C 2593266 rluC 3079332 rluC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosomal large subunit (23S rRNA) pseudouridine synthase C YP_096304.1 2592313 R 272624 CDS YP_096305.1 52842506 3079334 2593774..2594085 1 NC_002942.5 hypothetical protein 2594085 3079334 lpg2296 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096305.1 2593774 D 272624 CDS YP_096306.1 52842507 3079343 2594148..2596151 1 NC_002942.5 ribonuclease E 2596151 rne 3079343 rne Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease E YP_096306.1 2594148 D 272624 CDS YP_096307.1 52842508 3079356 complement(2596514..2597791) 1 NC_002942.5 conserved gene; coiled-coil-containing protein; inclusion membrane protein A 2597791 legC7 3079356 legC7 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inclusion membrane protein A YP_096307.1 2596514 R 272624 CDS YP_096308.1 52842509 3079371 2598385..2601261 1 NC_002942.5 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 2601261 hepA 3079371 hepA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent helicase HepA YP_096308.1 2598385 D 272624 CDS YP_096309.1 52842510 3079375 complement(2601375..2602778) 1 NC_002942.5 ankyrin repeat-containing protein 2602778 legA3 3079375 legA3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096309.1 2601375 R 272624 CDS YP_096310.1 52842511 3079381 complement(2602779..2603561) 1 NC_002942.5 hypothetical protein 2603561 3079381 lpg2301 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096310.1 2602779 R 272624 CDS YP_096311.1 52842512 3079388 complement(2603700..2604722) 1 NC_002942.5 aspartate semialdehyde dehydrogenase 2604722 asd 3079388 asd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartate semialdehyde dehydrogenase YP_096311.1 2603700 R 272624 CDS YP_096312.1 52842513 3079397 complement(2604832..2605890) 1 NC_002942.5 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2605890 3079397 lpg2303 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chorismate synthase YP_096312.1 2604832 R 272624 CDS YP_096313.1 52842514 3079412 complement(2605902..2606834) 1 NC_002942.5 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2606834 3079412 lpg2304 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_096313.1 2605902 R 272624 CDS YP_096314.1 52842515 3079417 2606999..2607568 1 NC_002942.5 Smr domain-containing protein 2607568 3079417 lpg2305 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Smr domain-containing protein YP_096314.1 2606999 D 272624 CDS YP_096315.1 52842516 3079424 2607641..2608060 1 NC_002942.5 rhodanese domain-containing protein 2608060 3079424 lpg2306 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rhodanese domain-containing protein YP_096315.1 2607641 D 272624 CDS YP_096316.1 52842517 3079434 2608065..2608319 1 NC_002942.5 glutaredoxin 2608319 grxC 3079434 grxC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutaredoxin YP_096316.1 2608065 D 272624 CDS YP_096317.1 52842518 3079440 2608329..2608817 1 NC_002942.5 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 2608817 secB 3079440 secB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecB YP_096317.1 2608329 D 272624 CDS YP_096318.1 52842519 3079447 2608741..2609808 1 NC_002942.5 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2609808 gpsA 3079447 gpsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_096318.1 2608741 D 272624 CDS YP_096319.1 52842520 3079452 complement(2609894..2610760) 1 NC_002942.5 glutamate racemase 2610760 murI 3079452 murI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamate racemase YP_096319.1 2609894 R 272624 CDS YP_096320.1 52842521 3079453 complement(2610805..2614308) 1 NC_002942.5 interaptin 2614308 3079453 lpg2311 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 interaptin YP_096320.1 2610805 R 272624 CDS YP_096321.1 52842522 3079465 2614430..2614732 1 NC_002942.5 hypothetical protein 2614732 3079465 lpg2312 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096321.1 2614430 D 272624 CDS YP_096322.1 52842523 3079470 complement(2614736..2616028) 1 NC_002942.5 hypothetical protein 2616028 3079470 lpg2313 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096322.1 2614736 R 272624 CDS YP_096323.1 52842524 3079472 complement(2616283..2617155) 1 NC_002942.5 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2617155 3079472 lpg2314 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydrodipicolinate synthase YP_096323.1 2616283 R 272624 CDS YP_096324.1 52842525 3079473 2617334..2617618 1 NC_002942.5 hypothetical protein 2617618 3079473 lpg2315 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096324.1 2617334 D 272624 CDS YP_096325.1 52842526 3079482 2617896..2618678 1 NC_002942.5 catalyzes the formation of acetoacetate from 3-hydroxybutyrate; 3-hydroxybutyrate dehydrogenase 2618678 bdhA 3079482 bdhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-hydroxybutyrate dehydrogenase YP_096325.1 2617896 D 272624 CDS YP_096326.1 52842527 3078784 2618685..2619845 1 NC_002942.5 transmembrane protein 2619845 3078784 lpg2317 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096326.1 2618685 D 272624 CDS YP_096327.1 52842528 3079322 2619875..2620780 1 NC_002942.5 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2620780 motA 3079322 motA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor protein MotA YP_096327.1 2619875 D 272624 CDS YP_096328.1 52842529 3079318 2620790..2621728 1 NC_002942.5 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2621728 motB 3079318 motB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar motor protein MotB YP_096328.1 2620790 D 272624 CDS YP_096329.1 52842530 3079345 complement(2621794..2622267) 1 NC_002942.5 hypothetical protein 2622267 3079345 lpg2320 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096329.1 2621794 R 272624 CDS YP_096330.1 52842531 3079266 2622446..2623807 1 NC_002942.5 serine transporter 2623807 sdaC 3079266 sdaC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine transporter YP_096330.1 2622446 D 272624 CDS YP_096331.1 52842532 3079040 complement(2623900..2625825) 1 NC_002942.5 ankyrin repeat-containing protein 2625825 legA5 3079040 legA5 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096331.1 2623900 R 272624 CDS YP_096332.1 52842533 3079290 complement(2625912..2627033) 1 NC_002942.5 type II secretion system protein (twitching motility protein) 2627033 uptC 3079290 uptC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 type II secretion system protein (twitching motility protein) YP_096332.1 2625912 R 272624 CDS YP_096333.1 52842534 3079469 complement(2627123..2629051) 1 NC_002942.5 L-gulono-gamma-lactone oxidase 2629051 3079469 lpg2324 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-gulono-gamma-lactone oxidase YP_096333.1 2627123 R 272624 CDS YP_096334.1 52842535 3079460 complement(2629339..2630175) 1 NC_002942.5 hypothetical protein 2630175 3079460 lpg2325 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096334.1 2629339 R 272624 CDS YP_096335.1 52842536 3079346 complement(2630172..2631524) 1 NC_002942.5 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 2631524 radA 3079346 radA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA repair protein RadA YP_096335.1 2630172 R 272624 CDS YP_096336.1 52842537 3079094 2631759..2632652 1 NC_002942.5 hypothetical protein 2632652 3079094 lpg2327 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096336.1 2631759 D 272624 CDS YP_096337.1 52842538 3080604 2632916..2633299 1 NC_002942.5 hypothetical protein 2633299 3080604 lpg2328 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096337.1 2632916 D 272624 CDS YP_096338.1 52842539 3080498 2633493..2633723 1 NC_002942.5 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2633723 xseB 3080498 xseB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 exodeoxyribonuclease VII small subunit YP_096338.1 2633493 D 272624 CDS YP_096339.1 52842540 3080514 2633671..2634600 1 NC_002942.5 geranyltranstransferase 2634600 ispA 3080514 ispA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 geranyltranstransferase YP_096339.1 2633671 D 272624 CDS YP_096340.1 52842541 3080625 complement(2634644..2635648) 1 NC_002942.5 biotin synthase 2635648 bioC 3080625 bioC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 biotin synthase YP_096340.1 2634644 R 272624 CDS YP_096341.1 52842542 3080500 2635647..2636246 1 NC_002942.5 competence protein ComF 2636246 3080500 lpg2332 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 competence protein ComF YP_096341.1 2635647 D 272624 CDS YP_096342.1 52842543 3080511 complement(2636275..2637366) 1 NC_002942.5 membrane associated zinc metalloprotease 2637366 3080511 lpg2333 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane associated zinc metalloprotease YP_096342.1 2636275 R 272624 CDS YP_096343.1 52842544 3080505 complement(2637405..2637683) 1 NC_002942.5 hypothetical protein 2637683 3080505 lpg2334 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096343.1 2637405 R 272624 CDS YP_096344.1 52842545 3080536 2637893..2639275 1 NC_002942.5 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2639275 hemA 3080536 hemA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamyl-tRNA reductase YP_096344.1 2637893 D 272624 CDS YP_096345.1 52842546 3080231 2639259..2640347 1 NC_002942.5 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2640347 prfA 3080231 prfA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide chain release factor 1 YP_096345.1 2639259 D 272624 CDS YP_096346.1 52842547 3080341 2640340..2641203 1 NC_002942.5 protein methyltransferase HemK 2641203 3080341 lpg2337 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein methyltransferase HemK YP_096346.1 2640340 D 272624 CDS YP_096347.1 52842548 3080589 2641302..2641778 1 NC_002942.5 DnaK suppressor protein 2641778 dksA 3080589 dksA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DnaK suppressor protein YP_096347.1 2641302 D 272624 CDS YP_096348.1 52842549 3080195 2641848..2642681 1 NC_002942.5 hypothetical protein 2642681 3080195 lpg2339 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096348.1 2641848 D 272624 CDS YP_096349.1 52842550 3080633 complement(2642686..2643951) 1 NC_002942.5 3-deoxy-D-manno-oct-2-ulosonic acid transferase 2643951 kdtA 3080633 kdtA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-deoxy-D-manno-oct-2-ulosonic acid transferase YP_096349.1 2642686 R 272624 CDS YP_096350.2 161723245 3080541 2644100..2644990 1 NC_002942.5 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 2644990 djlA 3080541 djlA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Dna-J like membrane chaperone protein YP_096350.2 2644100 D 272624 CDS YP_096351.1 52842552 3080485 complement(2644957..2645730) 1 NC_002942.5 hypothetical protein 2645730 3080485 lpg2342 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096351.1 2644957 R 272624 CDS YP_096352.1 52842553 3080220 complement(2645922..2646899) 1 NC_002942.5 lysophospholipase A 2646899 sseJ 3080220 sseJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lysophospholipase A YP_096352.1 2645922 R 272624 CDS YP_096353.1 52842554 3080418 2647010..2647636 1 NC_002942.5 hypothetical protein 2647636 3080418 lpg2344 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096353.1 2647010 D 272624 CDS YP_096354.1 52842555 3080524 complement(2648364..2650133) 1 NC_002942.5 ATP-dependent RNA helicase 2650133 deaD 3080524 deaD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent RNA helicase YP_096354.1 2648364 R 272624 CDS YP_096355.1 52842556 3080452 complement(2650501..2651439) 1 NC_002942.5 transcriptional regulator 2651439 3080452 lpg2346 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator YP_096355.1 2650501 R 272624 CDS YP_096356.1 52842557 3080518 complement(2651415..2653439) 1 NC_002942.5 2,4-dienoyl-CoA reductase 2653439 fadH 3080518 fadH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2,4-dienoyl-CoA reductase YP_096356.1 2651415 R 272624 CDS YP_096357.1 52842558 3080573 2653744..2654232 1 NC_002942.5 superoxide dismutase 2654232 sodC 3080573 sodC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 superoxide dismutase YP_096357.1 2653744 D 272624 CDS YP_096358.2 161723244 3079344 complement(2654276..2654791) 1 NC_002942.5 alkylhydroperoxidase 2654791 3079344 lpg2349 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkylhydroperoxidase YP_096358.2 2654276 R 272624 CDS YP_096359.1 52842560 3080617 complement(2654814..2655452) 1 NC_002942.5 alkylhydroperoxidase 2655452 3080617 lpg2350 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkylhydroperoxidase YP_096359.1 2654814 R 272624 CDS YP_096360.1 52842561 3080583 2655484..2656404 1 NC_002942.5 hypothetical protein 2656404 3080583 lpg2351 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096360.1 2655484 D 272624 CDS YP_096361.1 52842562 3080587 complement(2656503..2657495) 1 NC_002942.5 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 2657495 mdh 3080587 mdh Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malate dehydrogenase YP_096361.1 2656503 R 272624 CDS YP_096362.1 52842563 3080502 complement(2657485..2658048) 1 NC_002942.5 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 2658048 nudE 3080502 nudE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ADP-ribose diphosphatase NudE YP_096362.1 2657485 R 272624 CDS YP_096363.1 52842564 3080434 2658127..2659254 1 NC_002942.5 (oxygen-independent) coproporphyrinogen III oxidase 2659254 3080434 lpg2354 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (oxygen-independent) coproporphyrinogen III oxidase YP_096363.1 2658127 D 272624 CDS YP_096364.1 52842565 3080459 complement(2659286..2660695) 1 NC_002942.5 amidase 2660695 3080459 lpg2355 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amidase YP_096364.1 2659286 R 272624 CDS YP_096365.1 52842566 3080276 2661049..2661882 1 NC_002942.5 hypothetical protein 2661882 3080276 lpg2356 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096365.1 2661049 D 272624 CDS YP_096366.1 52842567 3080523 complement(2662056..2663057) 1 NC_002942.5 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 2663057 gcp 3080523 gcp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-binding/iron metalloprotein/AP endonuclease YP_096366.1 2662056 R 272624 CDS YP_096367.1 52842568 3080329 2663262..2663501 1 NC_002942.5 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 2663501 rpsU 3080329 rpsU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S21 YP_096367.1 2663262 D 272624 CDS YP_096368.1 52842569 3080513 2663704..2664147 1 NC_002942.5 hypothetical protein 2664147 3080513 lpg2359 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096368.1 2663704 D 272624 CDS YP_096369.1 52842570 3080366 2664144..2665889 1 NC_002942.5 DNA primase DnaG 2665889 3080366 lpg2360 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA primase DnaG YP_096369.1 2664144 D 272624 CDS YP_096370.1 52842571 3080194 2665970..2667841 1 NC_002942.5 RNA polymerase sigma 70 factor (RpoD) 2667841 rpoD 3080194 rpoD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA polymerase sigma 70 factor (RpoD) YP_096370.1 2665970 D 272624 CDS YP_096371.1 52842572 3080188 complement(2668117..2669316) 1 NC_002942.5 transposase (IS652) 2669316 3080188 lpg2363 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase (IS652) YP_096371.1 2668117 R 272624 CDS YP_096372.1 52842573 3080330 2669531..2669896 1 NC_002942.5 hypothetical protein 2669896 3080330 lpg2364 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096372.1 2669531 D 272624 CDS YP_096373.1 52842574 3080211 complement(2670253..2670618) 1 NC_002942.5 hypothetical protein 2670618 3080211 lpg2365 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096373.1 2670253 R 272624 CDS YP_096374.1 52842575 3080387 complement(2670946..2672697) 1 NC_002942.5 hypothetical protein 2672697 3080387 lpg2366 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096374.1 2670946 R 272624 CDS YP_096375.1 52842576 3080454 complement(2672763..2673038) 1 NC_002942.5 hypothetical protein 2673038 3080454 lpg2367 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096375.1 2672763 R 272624 CDS YP_096376.1 52842577 3080370 2673871..2674098 1 NC_002942.5 hypothetical protein 2674098 3080370 lpg2368 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096376.1 2673871 D 272624 CDS YP_096377.1 52842578 3080388 2674095..2674403 1 NC_002942.5 HipA protein 2674403 3080388 lpg2369 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HipA protein YP_096377.1 2674095 D 272624 CDS YP_096378.1 52842579 3080599 2674400..2675338 1 NC_002942.5 hypothetical protein 2675338 3080599 lpg2370 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096378.1 2674400 D 272624 CDS YP_096379.1 52842580 3080425 2675881..2676495 1 NC_002942.5 hypothetical protein 2676495 3080425 lpg2371 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096379.1 2675881 D 272624 CDS YP_096380.1 52842581 3080201 2677194..2678462 1 NC_002942.5 hypothetical protein 2678462 3080201 lpg2372 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096380.1 2677194 D 272624 CDS YP_096381.1 52842582 3080148 complement(2679203..2679874) 1 NC_002942.5 hypothetical protein 2679874 3080148 lpg2373 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096381.1 2679203 R 272624 CDS YP_096382.1 52842583 3080287 complement(2680222..2680533) 1 NC_002942.5 mannose-6-phosphate isomerase 2680533 3080287 lpg2374 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mannose-6-phosphate isomerase YP_096382.1 2680222 R 272624 CDS YP_096383.1 52842584 3080406 2680981..2681454 1 NC_002942.5 hypothetical protein 2681454 3080406 lpg2375 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096383.1 2680981 D 272624 CDS YP_096384.1 52842585 3080399 2681646..2682563 1 NC_002942.5 LysR family transcriptional regulator 2682563 3080399 lpg2376 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_096384.1 2681646 D 272624 CDS YP_096385.1 52842586 3080359 2683004..2683231 1 NC_002942.5 hypothetical protein 2683231 3080359 lpg2377 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096385.1 2683004 D 272624 CDS YP_096386.1 52842587 3080300 2683228..2683401 1 NC_002942.5 HipA-like protein 2683401 3080300 lpg2378 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 HipA-like protein YP_096386.1 2683228 D 272624 CDS YP_096387.1 52842588 3080376 2683534..2683884 1 NC_002942.5 hypothetical protein 2683884 3080376 lpg2379 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096387.1 2683534 D 272624 CDS YP_096388.1 52842589 3080324 2683844..2684452 1 NC_002942.5 hypothetical protein 2684452 3080324 lpg2380 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096388.1 2683844 D 272624 CDS YP_096389.1 52842590 3080315 2684581..2687148 1 NC_002942.5 magnesium-transporting ATPase, P-type 2687148 mgt 3080315 mgt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 magnesium-transporting ATPase, P-type YP_096389.1 2684581 D 272624 CDS YP_096390.1 52842591 3080157 2687420..2688874 1 NC_002942.5 hypothetical protein 2688874 3080157 lpg2382 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096390.1 2687420 D 272624 CDS YP_096391.1 52842592 3080568 2689113..2690039 1 NC_002942.5 LysR family transcriptional regulator 2690039 3080568 lpg2383 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_096391.1 2689113 D 272624 CDS YP_096392.1 52842593 3080479 2690122..2692047 1 NC_002942.5 Kup system potassium uptake protein 2692047 kup 3080479 kup Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Kup system potassium uptake protein YP_096392.1 2690122 D 272624 CDS YP_096393.1 52842594 3080302 2692257..2694044 1 NC_002942.5 hypothetical protein 2694044 3080302 lpg2385 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096393.1 2692257 D 272624 CDS YP_096394.1 52842595 3080311 2694370..2694933 1 NC_002942.5 hypothetical protein 2694933 3080311 lpg2386 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096394.1 2694370 D 272624 CDS YP_096395.1 52842596 3080288 complement(2695048..2695974) 1 NC_002942.5 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 2695974 pla 3080288 pla Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane protease YP_096395.1 2695048 R 272624 CDS YP_096396.1 52842597 3080173 complement(2696102..2697832) 1 NC_002942.5 amino acid permease 2697832 3080173 lpg2388 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid permease YP_096396.1 2696102 R 272624 CDS YP_096397.1 52842598 3080441 2698010..2700205 1 NC_002942.5 catalase-peroxidase KatB 2700205 3080441 lpg2389 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 catalase-peroxidase KatB YP_096397.1 2698010 D 272624 CDS YP_096398.1 52842599 3080145 complement(2700982..2702220) 1 NC_002942.5 proline/betaine transporter 2702220 proP1 3080145 proP1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 proline/betaine transporter YP_096398.1 2700982 R 272624 CDS YP_096399.1 52842600 3079400 complement(2702256..2703560) 1 NC_002942.5 protein SdbC 2703560 sdbC 3079400 sdbC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdbC YP_096399.1 2702256 R 272624 CDS YP_096400.1 52842601 3079407 2703828..2704712 1 NC_002942.5 hypothetical protein 2704712 legL6 3079407 legL6 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096400.1 2703828 D 272624 CDS YP_096401.1 52842602 3079168 complement(2704832..2705311) 1 NC_002942.5 bacterioferritin (cytochrome b1) 2705311 3079168 lpg2393 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bacterioferritin (cytochrome b1) YP_096401.1 2704832 R 272624 CDS YP_096402.1 52842603 3080166 2705410..2705643 1 NC_002942.5 hypothetical protein 2705643 3080166 lpg2394 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096402.1 2705410 D 272624 CDS YP_096403.1 52842604 3080279 2705662..2706054 1 NC_002942.5 hypothetical protein 2706054 3080279 lpg2395 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096403.1 2705662 D 272624 CDS YP_096404.1 52842605 3080384 complement(2706182..2707252) 1 NC_002942.5 transcriptional regulator 2707252 3080384 lpg2396 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator YP_096404.1 2706182 R 272624 CDS YP_096405.1 52842606 3080146 complement(2707622..2708821) 1 NC_002942.5 secreted peptidase 2708821 3080146 lpg2397 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 secreted peptidase YP_096405.1 2707622 R 272624 CDS YP_096406.1 52842607 3080259 complement(2708876..2709448) 1 NC_002942.5 aminoglycoside 6'-N-acetyltransferase 2709448 3080259 lpg2398 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminoglycoside 6'-N-acetyltransferase YP_096406.1 2708876 R 272624 CDS YP_096407.1 52842608 3080385 complement(2709638..2710984) 1 NC_002942.5 virulence protein 2710984 3080385 lpg2399 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 virulence protein YP_096407.1 2709638 R 272624 CDS YP_096408.1 52842609 3080154 2711277..2712341 1 NC_002942.5 hypothetical protein 2712341 legL7 3080154 legL7 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096408.1 2711277 D 272624 CDS YP_096409.1 52842610 3080155 2712550..2714076 1 NC_002942.5 secreted esterase 2714076 3080155 lpg2401 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 secreted esterase YP_096409.1 2712550 D 272624 CDS YP_096410.1 52842611 3080440 complement(2714053..2714973) 1 NC_002942.5 LysR family transcriptional regulator 2714973 3080440 lpg2402 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LysR family transcriptional regulator YP_096410.1 2714053 R 272624 CDS YP_096411.1 52842612 3080469 complement(2715158..2715697) 1 NC_002942.5 hypothetical protein 2715697 3080469 lpg2403 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096411.1 2715158 R 272624 CDS YP_096412.1 52842613 3080509 2715994..2716908 1 NC_002942.5 hypothetical protein 2716908 3080509 lpg2404 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096412.1 2715994 D 272624 CDS YP_096413.1 52842614 3080212 2716905..2717306 1 NC_002942.5 mutator MutT protein 2717306 mutT 3080212 mutT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 mutator MutT protein YP_096413.1 2716905 D 272624 CDS YP_096414.1 52842615 3080216 2717701..2718798 1 NC_002942.5 hypothetical protein 2718798 3080216 lpg2406 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096414.1 2717701 D 272624 CDS YP_096415.1 52842616 3080427 complement(2718993..2719298) 1 NC_002942.5 hypothetical protein 2719298 3080427 lpg2407 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096415.1 2718993 R 272624 CDS YP_096416.1 52842617 3080213 2719521..2720180 1 NC_002942.5 hypothetical protein 2720180 3080213 lpg2408 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096416.1 2719521 D 272624 CDS YP_096417.1 52842618 3080394 2720506..2721324 1 NC_002942.5 hypothetical protein 2721324 3080394 lpg2409 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096417.1 2720506 D 272624 CDS YP_096418.1 52842619 3080414 2721767..2723764 1 NC_002942.5 patatin-like phospholipase 2723764 3080414 lpg2410 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 patatin-like phospholipase YP_096418.1 2721767 D 272624 CDS YP_096419.1 52842620 3080210 complement(2723867..2724694) 1 NC_002942.5 hypothetical protein 2724694 3080210 lpg2411 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096419.1 2723867 R 272624 CDS YP_096420.2 161723243 3080398 2725235..2726314 1 NC_002942.5 beta-lactamase 2726314 ampC 3080398 ampC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 beta-lactamase YP_096420.2 2725235 D 272624 CDS YP_096421.1 52842622 3080207 2726509..2726946 1 NC_002942.5 hypothetical protein 2726946 3080207 lpg2413 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096421.1 2726509 D 272624 CDS YP_096422.1 52842623 3080204 complement(2727146..2727439) 1 NC_002942.5 hypothetical protein 2727439 3080204 lpg2414 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096422.1 2727146 R 272624 CDS YP_096423.1 52842624 3080202 complement(2727588..2727779) 1 NC_002942.5 transmembrane protein 2727779 3080202 lpg2415 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096423.1 2727588 R 272624 CDS YP_096424.1 52842625 3080619 2728074..2729180 1 NC_002942.5 ankyrin repeat-containing protein 2729180 legA1 3080619 legA1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096424.1 2728074 D 272624 CDS YP_096425.1 52842626 3080408 2729291..2730136 1 NC_002942.5 hypothetical protein 2730136 3080408 lpg2417 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096425.1 2729291 D 272624 CDS YP_096426.1 52842627 3080327 2730149..2731864 1 NC_002942.5 penicillin-binding protein AmpH 2731864 3080327 lpg2418 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 penicillin-binding protein AmpH YP_096426.1 2730149 D 272624 CDS YP_096427.1 52842628 3080208 complement(2731994..2732788) 1 NC_002942.5 hypothetical protein 2732788 3080208 lpg2419 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096427.1 2731994 R 272624 CDS YP_096428.1 52842629 3080198 2732983..2733534 1 NC_002942.5 hypothetical protein 2733534 3080198 lpg2420 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096428.1 2732983 D 272624 CDS YP_096429.1 52842630 3080165 2733597..2734676 1 NC_002942.5 transposase (ISSod13) 2734676 3080165 lpg2421 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase (ISSod13) YP_096429.1 2733597 D 272624 CDS YP_096430.1 52842631 3080196 complement(2734836..2737097) 1 NC_002942.5 hypothetical protein 2737097 3080196 lpg2422 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096430.1 2734836 R 272624 CDS YP_096431.1 52842632 3080377 2737386..2739116 1 NC_002942.5 hypothetical protein 2739116 3080377 lpg2423 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096431.1 2737386 D 272624 CDS YP_096432.1 52842633 3080190 complement(2739205..2740551) 1 NC_002942.5 hypothetical protein 2740551 3080190 lpg2424 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096432.1 2739205 R 272624 CDS YP_096433.1 52842634 3080369 complement(2741056..2741862) 1 NC_002942.5 hypothetical protein 2741862 3080369 lpg2425 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096433.1 2741056 R 272624 CDS YP_096434.1 52842635 3080187 2742145..2743791 1 NC_002942.5 malonate decarboxylase subunit alpha 2743791 mdcA 3080187 mdcA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malonate decarboxylase subunit alpha YP_096434.1 2742145 D 272624 CDS YP_096435.1 52842636 3080189 2743785..2744996 1 NC_002942.5 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; malonate decarboxylase subunit beta 2744996 mdcB 3080189 mdcB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malonate decarboxylase subunit beta YP_096435.1 2743785 D 272624 CDS YP_096436.1 52842637 3080263 2744997..2745716 1 NC_002942.5 malonate decarboxylase subunit gamma 2745716 mdcC 3080263 mdcC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malonate decarboxylase subunit gamma YP_096436.1 2744997 D 272624 CDS YP_096437.1 52842638 3080184 2745713..2746336 1 NC_002942.5 nucleotidyltransferases 2746336 mdcG 3080184 mdcG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nucleotidyltransferases YP_096437.1 2745713 D 272624 CDS YP_096438.1 52842639 3079432 2746308..2747150 1 NC_002942.5 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 2747150 mdcB 3079432 mdcB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_096438.1 2746308 D 272624 CDS YP_096439.1 52842640 3079486 2747147..2748094 1 NC_002942.5 malonyl CoA-ACP transacylase 2748094 3079486 lpg2431 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malonyl CoA-ACP transacylase YP_096439.1 2747147 D 272624 CDS YP_096440.1 52842641 3079127 2748442..2749101 1 NC_002942.5 alkaline phosphatase 2749101 phoA 3079127 phoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkaline phosphatase YP_096440.1 2748442 D 272624 CDS YP_096441.1 52842642 3080632 2749238..2750998 1 NC_002942.5 hypothetical protein 2750998 3080632 lpg2433 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096441.1 2749238 D 272624 CDS YP_096442.1 52842643 3080390 2751265..2751759 1 NC_002942.5 hypothetical protein 2751759 3080390 lpg2434 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096442.1 2751265 D 272624 CDS YP_096443.1 52842644 3080183 2751786..2752829 1 NC_002942.5 hypothetical protein 2752829 3080183 lpg2435 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096443.1 2751786 D 272624 CDS YP_096444.1 52842645 3079446 2752866..2753246 1 NC_002942.5 hypothetical protein 2753246 3079446 lpg2436 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096444.1 2752866 D 272624 CDS YP_096445.1 52842646 3080395 2753317..2753505 1 NC_002942.5 hypothetical protein 2753505 3080395 lpg2437 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096445.1 2753317 D 272624 CDS YP_096446.1 52842647 3080219 complement(2753605..2754795) 1 NC_002942.5 florfenicol efflux pump 2754795 3080219 lpg2438 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 florfenicol efflux pump YP_096446.1 2753605 R 272624 CDS YP_096447.1 52842648 3080268 complement(2755062..2755613) 1 NC_002942.5 NADPH-dependent FMN reductase domain-containing protein 2755613 3080268 lpg2439 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADPH-dependent FMN reductase domain-containing protein YP_096447.1 2755062 R 272624 CDS YP_096448.1 52842649 3080223 2755705..2756721 1 NC_002942.5 glutathione S-transferase 2756721 3080223 lpg2440 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutathione S-transferase YP_096448.1 2755705 D 272624 CDS YP_096449.1 52842650 3080180 2756759..2757232 1 NC_002942.5 DNA binding protein 2757232 3080180 lpg2441 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA binding protein YP_096449.1 2756759 D 272624 CDS YP_096450.1 52842651 3080553 2757333..2757743 1 NC_002942.5 PhnB protein 2757743 3080553 lpg2442 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 PhnB protein YP_096450.1 2757333 D 272624 CDS YP_096451.1 52842652 3080314 complement(2757867..2758424) 1 NC_002942.5 hypothetical protein 2758424 3080314 lpg2443 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096451.1 2757867 R 272624 CDS YP_096452.1 52842653 3080415 complement(2758651..2759265) 1 NC_002942.5 hypothetical protein 2759265 3080415 lpg2444 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096452.1 2758651 R 272624 CDS YP_096453.1 52842654 3080435 2759412..2759897 1 NC_002942.5 hypothetical protein 2759897 3080435 lpg2445 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096453.1 2759412 D 272624 CDS YP_096454.1 52842655 3080171 2759982..2760260 1 NC_002942.5 hypothetical protein 2760260 3080171 lpg2446 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096454.1 2759982 D 272624 CDS YP_096455.1 52842656 3080163 complement(2760549..2760986) 1 NC_002942.5 transposase, ISSod6 2760986 3080163 lpg2448 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase, ISSod6 YP_096455.1 2760549 R 272624 CDS YP_096456.1 52842657 3080516 2761307..2762032 1 NC_002942.5 D-alanyl-D-alanine dipeptidase 2762032 3080516 lpg2449 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanyl-D-alanine dipeptidase YP_096456.1 2761307 D 272624 CDS YP_096457.1 52842658 3080174 2762115..2762843 1 NC_002942.5 hypothetical protein 2762843 3080174 lpg2450 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096457.1 2762115 D 272624 CDS YP_096458.1 52842659 3080170 complement(2762922..2763890) 1 NC_002942.5 N-hydroxyarylamine O-acetyltransferase 2763890 3080170 lpg2451 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-hydroxyarylamine O-acetyltransferase YP_096458.1 2762922 R 272624 CDS YP_096459.1 52842660 3080416 complement(2764049..2766814) 1 NC_002942.5 ankyrin repeat-containing protein 2766814 legA14 3080416 legA14 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096459.1 2764049 R 272624 CDS YP_096460.1 52842661 3080159 complement(2767580..2768029) 1 NC_002942.5 hypothetical protein 2768029 3080159 lpg2453 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096460.1 2767580 R 272624 CDS YP_096461.1 52842662 3080255 2768334..2768780 1 NC_002942.5 acetyltransferase 2768780 3080255 lpg2454 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetyltransferase YP_096461.1 2768334 D 272624 CDS YP_096462.1 52842663 3080312 2769090..2769719 1 NC_002942.5 hypothetical protein 2769719 3080312 lpg2455 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096462.1 2769090 D 272624 CDS YP_096463.1 52842664 3080304 2769925..2771340 1 NC_002942.5 ankyrin repeat-containing protein 2771340 legA15 3080304 legA15 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ankyrin repeat-containing protein YP_096463.1 2769925 D 272624 CDS YP_096464.1 52842665 3080353 complement(2771352..2771762) 1 NC_002942.5 two component response regulator 2771762 3080353 lpg2457 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 two component response regulator YP_096464.1 2771352 R 272624 CDS YP_096465.1 52842666 3080275 complement(2771823..2773103) 1 NC_002942.5 sensory box histidine kinase 2773103 3080275 lpg2458 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box histidine kinase YP_096465.1 2771823 R 272624 CDS YP_096466.1 52842667 3080282 complement(2773093..2773653) 1 NC_002942.5 guanylate cyclase 2773653 3080282 lpg2459 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 guanylate cyclase YP_096466.1 2773093 R 272624 CDS YP_096467.1 52842668 3080396 complement(2773873..2774256) 1 NC_002942.5 hypothetical protein 2774256 3080396 lpg2460 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096467.1 2773873 R 272624 CDS YP_096468.1 52842669 3080269 2774397..2775035 1 NC_002942.5 hypothetical protein 2775035 3080269 lpg2461 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096468.1 2774397 D 272624 CDS YP_096469.1 52842670 3080478 2775242..2776174 1 NC_002942.5 hypothetical protein 2776174 3080478 lpg2462 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096469.1 2775242 D 272624 CDS YP_096470.1 52842671 3080221 2776438..2777157 1 NC_002942.5 peptide aspartate b-dioxygenase 2777157 3080221 lpg2463 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide aspartate b-dioxygenase YP_096470.1 2776438 D 272624 CDS YP_096471.1 52842672 3080368 complement(2777324..2779267) 1 NC_002942.5 hypothetical protein 2779267 3080368 lpg2464 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096471.1 2777324 R 272624 CDS YP_096472.1 52842673 3080576 2779337..2780860 1 NC_002942.5 protein SidD 2780860 sidD 3080576 sidD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidD YP_096472.1 2779337 D 272624 CDS YP_096473.1 52842674 3080614 complement(2780889..2781368) 1 NC_002942.5 hydrogenase expression/formation protein 2781368 vhtD 3080614 vhtD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase expression/formation protein YP_096473.1 2780889 R 272624 CDS YP_096474.1 52842675 3080525 complement(2781365..2782657) 1 NC_002942.5 cytochrome c3 hydrogenase alpha chain 2782657 hydA 3080525 hydA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c3 hydrogenase alpha chain YP_096474.1 2781365 R 272624 CDS YP_096475.1 52842676 3080345 complement(2782650..2783435) 1 NC_002942.5 sulfhydrogenase subunit delta 2783435 3080345 lpg2468 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfhydrogenase subunit delta YP_096475.1 2782650 R 272624 CDS YP_096476.1 52842677 3080289 complement(2783453..2784298) 1 NC_002942.5 hydrogenase/sulfur reductase subunit gamma 2784298 hydG-2 3080289 hydG-2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase/sulfur reductase subunit gamma YP_096476.1 2783453 R 272624 CDS YP_096477.1 52842678 3080483 complement(2784291..2785502) 1 NC_002942.5 cytochrome c3 hydrogenase alpha (or beta) chain 2785502 3080483 lpg2470 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c3 hydrogenase alpha (or beta) chain YP_096477.1 2784291 R 272624 CDS YP_096478.1 52842679 3080297 complement(2785466..2786524) 1 NC_002942.5 hydrogenase expression/formation protein HypE 2786524 hypE 3080297 hypE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase expression/formation protein HypE YP_096478.1 2785466 R 272624 CDS YP_096479.1 52842680 3080277 complement(2786521..2787627) 1 NC_002942.5 hydrogenase expression/formation protein HypD 2787627 hypD 3080277 hypD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase expression/formation protein HypD YP_096479.1 2786521 R 272624 CDS YP_096480.1 52842681 3080260 complement(2787624..2787851) 1 NC_002942.5 hydrogenase expression/formation protein HypC 2787851 hypC 3080260 hypC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase expression/formation protein HypC YP_096480.1 2787624 R 272624 CDS YP_096481.1 52842682 3080433 complement(2787861..2790086) 1 NC_002942.5 hydrogenase maturation protein HypF 2790086 hypF 3080433 hypF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase maturation protein HypF YP_096481.1 2787861 R 272624 CDS YP_096482.1 52842683 3080248 complement(2790102..2790860) 1 NC_002942.5 hydrogenase nickel incorporation protein HypB 2790860 hypB 3080248 hypB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase nickel incorporation protein HypB YP_096482.1 2790102 R 272624 CDS YP_096483.1 52842684 3080411 complement(2790860..2791201) 1 NC_002942.5 hydrogenase nickel incorporation protein HypA 2791201 hypA 3080411 hypA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrogenase nickel incorporation protein HypA YP_096483.1 2790860 R 272624 CDS YP_096484.1 52842685 3080473 complement(2791213..2791980) 1 NC_002942.5 high affinity nickel transport protein 2791980 3080473 lpg2477 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 high affinity nickel transport protein YP_096484.1 2791213 R 272624 CDS YP_096485.1 52842686 3080294 2791964..2792995 1 NC_002942.5 glycosyltransferase, group 2 family protein (glycan biosynthesis) 2792995 3080294 lpg2478 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycosyltransferase, group 2 family protein (glycan biosynthesis) YP_096485.1 2791964 D 272624 CDS YP_096486.1 52842687 3080622 2792961..2793368 1 NC_002942.5 hypothetical protein 2793368 3080622 lpg2479 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096486.1 2792961 D 272624 CDS YP_096487.1 52842688 3080532 complement(2793345..2794157) 1 NC_002942.5 cellobiose phosphorylase 2794157 3080532 lpg2480 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cellobiose phosphorylase YP_096487.1 2793345 R 272624 CDS YP_096488.1 52842689 3080343 complement(2794324..2795226) 1 NC_002942.5 hypothetical protein 2795226 3080343 lpg2481 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096488.1 2794324 R 272624 CDS YP_096489.1 52842690 3080347 2795479..2796825 1 NC_002942.5 protein SdbC 2796825 3080347 lpg2482 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdbC YP_096489.1 2795479 D 272624 CDS YP_096490.1 52842691 3080504 complement(2796852..2797409) 1 NC_002942.5 hypothetical protein 2797409 3080504 lpg2483 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096490.1 2796852 R 272624 CDS YP_096491.1 52842692 3080400 2797458..2798042 1 NC_002942.5 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 2798042 3080400 lpg2484 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyribonucleotide triphosphate pyrophosphatase YP_096491.1 2797458 D 272624 CDS YP_096492.1 52842693 3080251 2798044..2799759 1 NC_002942.5 hypothetical protein 2799759 3080251 lpg2485 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096492.1 2798044 D 272624 CDS YP_096493.1 52842694 3080310 complement(2800077..2801465) 1 NC_002942.5 phosphomannomutase 2801465 3080310 lpg2486 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphomannomutase YP_096493.1 2800077 R 272624 CDS YP_096494.1 52842695 3080618 complement(2801466..2801936) 1 NC_002942.5 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 2801936 dut 3080618 dut Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_096494.1 2801466 R 272624 CDS YP_096495.1 52842696 3080538 complement(2801951..2803339) 1 NC_002942.5 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2803339 3080538 lpg2488 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_096495.1 2801951 R 272624 CDS YP_096496.1 52842697 3080442 2803224..2803907 1 NC_002942.5 DNA repair protein RadC 2803907 3080442 lpg2489 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA repair protein RadC YP_096496.1 2803224 D 272624 CDS YP_096497.1 52842698 3080286 2804259..2808143 1 NC_002942.5 hypothetical protein 2808143 lepB 3080286 lepB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096497.1 2804259 D 272624 CDS YP_096498.1 52842699 3080233 complement(2808266..2808829) 1 NC_002942.5 hypothetical protein 2808829 3080233 lpg2491 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096498.1 2808266 R 272624 CDS YP_096499.1 52842700 3080393 2809091..2810077 1 NC_002942.5 alcohol dehydrogenase 2810077 3080393 lpg2492 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alcohol dehydrogenase YP_096499.1 2809091 D 272624 CDS YP_096500.1 52842701 3080487 2810340..2810834 1 NC_002942.5 small heat shock protein HspC2 2810834 3080487 lpg2493 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 small heat shock protein HspC2 YP_096500.1 2810340 D 272624 CDS YP_096501.1 52842702 3080566 2811202..2811894 1 NC_002942.5 hypothetical protein 2811894 3080566 lpg2494 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096501.1 2811202 D 272624 CDS YP_096502.1 52842703 3080245 complement(2811945..2813363) 1 NC_002942.5 homospermidine synthase 2813363 hss 3080245 hss Legionella pneumophila subsp. pneumophila str. Philadelphia 1 homospermidine synthase YP_096502.1 2811945 R 272624 CDS YP_096503.1 52842704 3080232 2813566..2814090 1 NC_002942.5 RNA methyltransferase 2814090 3080232 lpg2496 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA methyltransferase YP_096503.1 2813566 D 272624 CDS YP_096504.1 52842705 3080293 complement(2814249..2814902) 1 NC_002942.5 hypothetical protein 2814902 3080293 lpg2497 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096504.1 2814249 R 272624 CDS YP_096505.1 52842706 3080466 2815381..2816313 1 NC_002942.5 hypothetical protein 2816313 3080466 lpg2498 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096505.1 2815381 D 272624 CDS YP_096506.1 52842707 3080558 2816981..2817553 1 NC_002942.5 lysine decarboxylase 2817553 3080558 lpg2499 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lysine decarboxylase YP_096506.1 2816981 D 272624 CDS YP_096507.1 52842708 3080226 2817593..2818330 1 NC_002942.5 carbonic anhydrase Mig5 2818330 3080226 lpg2500 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbonic anhydrase Mig5 YP_096507.1 2817593 D 272624 CDS YP_096508.1 52842709 3080474 2818415..2819647 1 NC_002942.5 multidrug resistance protein D 2819647 3080474 lpg2501 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multidrug resistance protein D YP_096508.1 2818415 D 272624 CDS YP_096509.1 52842710 3080522 complement(2819644..2819892) 1 NC_002942.5 hypothetical protein 2819892 3080522 lpg2502 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096509.1 2819644 R 272624 CDS YP_096510.1 52842711 3080160 complement(2820300..2820620) 1 NC_002942.5 hypothetical protein 2820620 3080160 lpg2503 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096510.1 2820300 R 272624 CDS YP_096511.1 52842712 3080582 2820928..2823756 1 NC_002942.5 hypothetical protein 2823756 3080582 lpg2504 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096511.1 2820928 D 272624 CDS YP_096512.1 52842713 3080307 2823758..2824645 1 NC_002942.5 hypothetical protein 2824645 3080307 lpg2505 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096512.1 2823758 D 272624 CDS YP_096513.1 52842714 3080192 2825042..2826304 1 NC_002942.5 sensor histidine kinase/response regulator LuxN 2826304 3080192 lpg2506 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor histidine kinase/response regulator LuxN YP_096513.1 2825042 D 272624 CDS YP_096514.1 52842715 3080256 complement(2826352..2827047) 1 NC_002942.5 hypothetical protein 2827047 3080256 lpg2507 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096514.1 2826352 R 272624 CDS YP_096515.1 52842716 3080486 complement(2827446..2829869) 1 NC_002942.5 hypothetical protein 2829869 3080486 lpg2508 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096515.1 2827446 R 272624 CDS YP_096516.1 52842717 3080595 complement(2829940..2831133) 1 NC_002942.5 protein SdeD 2831133 3080595 lpg2509 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdeD YP_096516.1 2829940 R 272624 CDS YP_096517.1 52842718 3080530 2831384..2834110 1 NC_002942.5 protein SdcA 2834110 3080530 lpg2510 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SdcA YP_096517.1 2831384 D 272624 CDS YP_096518.1 52842719 3080517 2834261..2837014 1 NC_002942.5 protein SidC, interaptin 2837014 sidC 3080517 sidC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidC, interaptin YP_096518.1 2834261 D 272624 CDS YP_096519.1 52842720 3080230 complement(2837380..2840532) 1 NC_002942.5 RND multidrug efflux transporter MexF 2840532 3080230 lpg2512 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RND multidrug efflux transporter MexF YP_096519.1 2837380 R 272624 CDS YP_096520.1 52842721 3080534 complement(2840592..2841758) 1 NC_002942.5 RND multidrug efflux membrane fusion protein 2841758 3080534 lpg2513 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RND multidrug efflux membrane fusion protein YP_096520.1 2840592 R 272624 CDS YP_096521.1 52842722 3080519 complement(2841752..2843314) 1 NC_002942.5 outer membrane efflux protein 2843314 3080519 lpg2514 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane efflux protein YP_096521.1 2841752 R 272624 CDS YP_096522.1 52842723 3080592 complement(2843496..2843861) 1 NC_002942.5 structural toxin protein (hemagglutinin/hemolysin) RtxA 2843861 3080592 lpg2515 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 structural toxin protein (hemagglutinin/hemolysin) RtxA YP_096522.1 2843496 R 272624 CDS YP_096523.1 52842724 3080554 complement(2843865..2845130) 1 NC_002942.5 major facilitator family transporter 2845130 3080554 lpg2516 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator family transporter YP_096523.1 2843865 R 272624 CDS YP_096524.1 52842725 3080335 2845298..2845771 1 NC_002942.5 AsnC family transcriptional regulator 2845771 3080335 lpg2517 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AsnC family transcriptional regulator YP_096524.1 2845298 D 272624 CDS YP_096525.1 52842726 3080615 2845967..2846308 1 NC_002942.5 hypothetical protein 2846308 3080615 lpg2518 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096525.1 2845967 D 272624 CDS YP_096526.1 52842727 3080455 2846499..2847059 1 NC_002942.5 hypothetical protein 2847059 3080455 lpg2519 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096526.1 2846499 D 272624 CDS YP_096527.1 52842728 3080551 complement(2847152..2847520) 1 NC_002942.5 hypothetical protein 2847520 3080551 lpg2520 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096527.1 2847152 R 272624 CDS YP_096528.1 52842729 3080555 2847611..2847790 1 NC_002942.5 hypothetical protein 2847790 3080555 lpg2521 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096528.1 2847611 D 272624 CDS YP_096529.1 52842730 3079125 complement(2847831..2848985) 1 NC_002942.5 metal-activated pyridoxal enzyme 2848985 3079125 lpg2522 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metal-activated pyridoxal enzyme YP_096529.1 2847831 R 272624 CDS YP_096530.1 52842731 3078983 2849475..2851814 1 NC_002942.5 hypothetical protein 2851814 3078983 lpg2523 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096530.1 2849475 D 272624 CDS YP_096531.1 52842732 3078806 2852006..2852869 1 NC_002942.5 LuxR family transcriptional regulator 2852869 3078806 lpg2524 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 LuxR family transcriptional regulator YP_096531.1 2852006 D 272624 CDS YP_096532.1 52842733 3079250 2852975..2854309 1 NC_002942.5 hypothetical protein 2854309 3079250 lpg2525 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096532.1 2852975 D 272624 CDS YP_096533.1 52842734 3079367 complement(2854590..2855957) 1 NC_002942.5 hypothetical protein 2855957 3079367 lpg2526 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096533.1 2854590 R 272624 CDS YP_096534.1 52842735 3079396 complement(2856264..2857940) 1 NC_002942.5 hypothetical protein 2857940 3079396 lpg2527 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096534.1 2856264 R 272624 CDS YP_096535.1 52842736 3078692 2858107..2859657 1 NC_002942.5 alpha-amylase 2859657 3078692 lpg2528 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alpha-amylase YP_096535.1 2858107 D 272624 CDS YP_096536.1 52842737 3079329 complement(2859811..2861529) 1 NC_002942.5 hypothetical protein 2861529 3079329 lpg2529 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096536.1 2859811 R 272624 CDS YP_096537.1 52842738 3079414 2862296..2863339 1 NC_002942.5 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2863339 aroF 3079414 aroF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_096537.1 2862296 D 272624 CDS YP_096538.1 52842739 3079387 2863336..2863920 1 NC_002942.5 chorismate mutase 2863920 3079387 lpg2531 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chorismate mutase YP_096538.1 2863336 D 272624 CDS YP_096539.1 52842740 3079285 2864214..2865380 1 NC_002942.5 aspartate aminotransferase 2865380 3079285 lpg2532 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartate aminotransferase YP_096539.1 2864214 D 272624 CDS YP_096540.1 52842741 3079121 2865682..2866578 1 NC_002942.5 with TehA confers resistance to tellurite; tellurite resistance protein TehB 2866578 tehB 3079121 tehB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tellurite resistance protein TehB YP_096540.1 2865682 D 272624 CDS YP_096541.1 52842742 3079380 complement(2866611..2867042) 1 NC_002942.5 hypothetical protein 2867042 3079380 lpg2534 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096541.1 2866611 R 272624 CDS YP_096542.1 52842743 3079379 2867089..2867496 1 NC_002942.5 hypothetical protein 2867496 3079379 lpg2535 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096542.1 2867089 D 272624 CDS YP_096543.1 52842744 3078754 2867493..2868449 1 NC_002942.5 ferredoxin reductase 2868449 3078754 lpg2536 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ferredoxin reductase YP_096543.1 2867493 D 272624 CDS YP_096544.1 52842745 3079258 2868674..2869693 1 NC_002942.5 5-carboxyvanillate decarboxylase 2869693 3079258 lpg2537 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 5-carboxyvanillate decarboxylase YP_096544.1 2868674 D 272624 CDS YP_096545.1 52842746 3079416 complement(2869817..2871232) 1 NC_002942.5 hypothetical protein 2871232 3079416 lpg2538 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096545.1 2869817 R 272624 CDS YP_096546.1 52842747 3079441 complement(2871814..2872221) 1 NC_002942.5 hypothetical protein 2872221 3079441 lpg2539 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096546.1 2871814 R 272624 CDS YP_096547.1 52842748 3078639 complement(2872433..2872816) 1 NC_002942.5 large conductance mechanosensitive channel 2872816 mscL 3078639 mscL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 large conductance mechanosensitive channel YP_096547.1 2872433 R 272624 CDS YP_096548.1 52842749 3079378 complement(2872931..2873764) 1 NC_002942.5 hypothetical protein 2873764 3079378 lpg2541 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096548.1 2872931 R 272624 CDS YP_096549.1 52842750 3079395 complement(2874050..2874541) 1 NC_002942.5 hypothetical protein 2874541 3079395 lpg2542 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096549.1 2874050 R 272624 CDS YP_096550.1 52842751 3079366 complement(2874608..2875273) 1 NC_002942.5 hypothetical protein 2875273 3079366 lpg2543 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096550.1 2874608 R 272624 CDS YP_096551.1 52842752 3079060 2875791..2877164 1 NC_002942.5 membrane-bound lytic murein transglycosylase A 2877164 mltA 3079060 mltA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 membrane-bound lytic murein transglycosylase A YP_096551.1 2875791 D 272624 CDS YP_096552.1 52842753 3078661 2877541..2877831 1 NC_002942.5 hypothetical protein 2877831 3078661 lpg2545 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096552.1 2877541 D 272624 CDS YP_096553.1 52842754 3079461 complement(2878610..2880019) 1 NC_002942.5 hypothetical protein 2880019 3079461 lpg2546 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096553.1 2878610 R 272624 CDS YP_096554.1 52842755 3079401 complement(2880193..2880528) 1 NC_002942.5 chaperonin CsaA 2880528 csaA 3079401 csaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chaperonin CsaA YP_096554.1 2880193 R 272624 CDS YP_096555.1 52842756 3079043 complement(2880538..2881452) 1 NC_002942.5 transmembrane protein 2881452 3079043 lpg2548 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096555.1 2880538 R 272624 CDS YP_096556.1 52842757 3079336 complement(2881518..2882288) 1 NC_002942.5 AraC family transcriptional regulator 2882288 3079336 lpg2549 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AraC family transcriptional regulator YP_096556.1 2881518 R 272624 CDS YP_096557.1 52842758 3079406 complement(2882559..2883128) 1 NC_002942.5 hypothetical protein 2883128 3079406 lpg2550 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096557.1 2882559 R 272624 CDS YP_096558.1 52842759 3079425 2883256..2884101 1 NC_002942.5 hypothetical protein 2884101 3079425 lpg2551 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096558.1 2883256 D 272624 CDS YP_096559.1 52842760 3078624 complement(2884137..2885804) 1 NC_002942.5 hypothetical protein 2885804 3078624 lpg2552 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096559.1 2884137 R 272624 CDS YP_096560.1 52842761 3078658 2885982..2887349 1 NC_002942.5 hexosephosphate transport 2887349 uhpC 3078658 uhpC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hexosephosphate transport YP_096560.1 2885982 D 272624 CDS YP_096561.1 52842762 3079153 2887612..2888094 1 NC_002942.5 rare lipoprotein A 2888094 3079153 lpg2554 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rare lipoprotein A YP_096561.1 2887612 D 272624 CDS YP_096562.1 52842763 3079115 complement(2888571..2889425) 1 NC_002942.5 hypothetical protein 2889425 3079115 lpg2555 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096562.1 2888571 R 272624 CDS YP_096563.1 52842764 3079439 2890013..2891401 1 NC_002942.5 Ser/Thr kinase; protein kinase 2891401 legK3 3079439 legK3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein kinase YP_096563.1 2890013 D 272624 CDS YP_096564.1 52842765 3079222 complement(2891426..2892154) 1 NC_002942.5 hypothetical protein 2892154 3079222 lpg2557 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096564.1 2891426 R 272624 CDS YP_096565.1 52842766 3079077 2892417..2892845 1 NC_002942.5 integrase of prophage CP-933C 2892845 3079077 lpg2558 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 integrase of prophage CP-933C YP_096565.1 2892417 D 272624 CDS YP_096566.1 52842767 3079320 2892852..2894309 1 NC_002942.5 ATP-dependent DNA helicase 2894309 recG 3079320 recG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent DNA helicase YP_096566.1 2892852 D 272624 CDS YP_096567.1 52842768 3079163 complement(2894489..2895076) 1 NC_002942.5 hypothetical protein 2895076 3079163 lpg2560 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096567.1 2894489 R 272624 CDS YP_096568.1 52842769 3079361 complement(2895245..2895847) 1 NC_002942.5 hypothetical protein 2895847 3079361 lpg2561 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096568.1 2895245 R 272624 CDS YP_096569.1 52842770 3079213 complement(2896086..2896763) 1 NC_002942.5 phage repressor 2896763 3079213 lpg2562 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phage repressor YP_096569.1 2896086 R 272624 CDS YP_096570.1 52842771 3079071 2896977..2897183 1 NC_002942.5 prophage regulatory protein-like 2897183 3079071 lpg2563 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prophage regulatory protein-like YP_096570.1 2896977 D 272624 CDS YP_096571.1 52842772 3079230 2897221..2897619 1 NC_002942.5 protein LvrA 2897619 3079230 lpg2564 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LvrA YP_096571.1 2897221 D 272624 CDS YP_096572.1 52842773 3079221 2898333..2898599 1 NC_002942.5 transposase ORF-A, IS-type 2898599 3079221 lpg2565 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transposase ORF-A, IS-type YP_096572.1 2898333 D 272624 CDS YP_096573.1 52842774 3079355 2898596..2899441 1 NC_002942.5 ISxcC1 transposase 2899441 3079355 lpg2566 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISxcC1 transposase YP_096573.1 2898596 D 272624 CDS YP_096574.1 52842775 3079310 complement(2899489..2900097) 1 NC_002942.5 ISI400 transposase B 2900097 3079310 lpg2567 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ISI400 transposase B YP_096574.1 2899489 R 272624 CDS YP_096575.1 52842776 3079372 complement(2900255..2901337) 1 NC_002942.5 hypothetical protein 2901337 3079372 lpg2568 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096575.1 2900255 R 272624 CDS YP_096576.1 52842777 3079046 complement(2901559..2901966) 1 NC_002942.5 hypothetical protein 2901966 3079046 lpg2569 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096576.1 2901559 R 272624 CDS YP_096577.1 52842778 3079354 complement(2902489..2903049) 1 NC_002942.5 hypothetical protein 2903049 3079354 lpg2571 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096577.1 2902489 R 272624 CDS YP_096578.1 52842779 3079242 complement(2903101..2903835) 1 NC_002942.5 hypothetical protein 2903835 3079242 lpg2572 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096578.1 2903101 R 272624 CDS YP_096579.1 52842780 3079249 complement(2903857..2904405) 1 NC_002942.5 resolvase 2904405 3079249 lpg2573 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 resolvase YP_096579.1 2903857 R 272624 CDS YP_096580.1 52842781 3079442 complement(2904635..2904871) 1 NC_002942.5 hypothetical protein 2904871 3079442 lpg2574 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096580.1 2904635 R 272624 CDS YP_096581.1 52842782 3079061 complement(2905190..2905567) 1 NC_002942.5 uroporphyrin-III C-methyltransferase 2905567 3079061 lpg2576 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uroporphyrin-III C-methyltransferase YP_096581.1 2905190 R 272624 CDS YP_096582.1 52842783 3079373 complement(2905863..2906621) 1 NC_002942.5 hypothetical protein 2906621 3079373 lpg2577 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096582.1 2905863 R 272624 CDS YP_096583.1 52842784 3079218 complement(2906717..2906971) 1 NC_002942.5 hypothetical protein 2906971 3079218 lpg2578 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096583.1 2906717 R 272624 CDS YP_096584.1 52842785 3079303 complement(2907214..2907627) 1 NC_002942.5 hypothetical protein 2907627 3079303 lpg2579 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096584.1 2907214 R 272624 CDS YP_096585.1 52842786 3079324 complement(2907822..2908979) 1 NC_002942.5 glutaryl CoA dehydrogenase 2908979 gcdH 3079324 gcdH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutaryl CoA dehydrogenase YP_096585.1 2907822 R 272624 CDS YP_096586.1 52842787 3079338 complement(2908957..2911227) 1 NC_002942.5 2-oxoisovalerate dehydrogenase E1 2911227 3079338 lpg2581 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 2-oxoisovalerate dehydrogenase E1 YP_096586.1 2908957 R 272624 CDS YP_096587.1 52842788 3079262 2911432..2912598 1 NC_002942.5 hypothetical protein 2912598 3079262 lpg2582 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096587.1 2911432 D 272624 CDS YP_096588.1 52842789 3079248 2912523..2912861 1 NC_002942.5 flagellar protein FlhB 2912861 3079248 lpg2583 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 flagellar protein FlhB YP_096588.1 2912523 D 272624 CDS YP_096589.1 52842790 3079117 2913345..2916083 1 NC_002942.5 inhibitor of growth protein SidF 2916083 sidF 3079117 sidF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inhibitor of growth protein SidF YP_096589.1 2913345 D 272624 CDS YP_096590.1 52842791 3079485 2916109..2916840 1 NC_002942.5 hypothetical protein 2916840 pcgL 3079485 pcgL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096590.1 2916109 D 272624 CDS YP_096591.1 52842792 3078729 2917042..2918136 1 NC_002942.5 cysteine protease 2918136 3078729 lpg2586 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cysteine protease YP_096591.1 2917042 D 272624 CDS YP_096592.1 52842793 3079298 2918357..2919907 1 NC_002942.5 thermolabile hemolysin 2919907 3079298 lpg2587 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thermolabile hemolysin YP_096592.1 2918357 D 272624 CDS YP_096593.1 52842794 3079295 complement(2919924..2921081) 1 NC_002942.5 acid sphingomyelinase-like phosphodiesterase 2921081 legS1 3079295 legS1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acid sphingomyelinase-like phosphodiesterase YP_096593.1 2919924 R 272624 CDS YP_096594.1 52842795 3079422 complement(2921870..2923663) 1 NC_002942.5 D-alanyl-D-alanine carboxypeptidase 2923663 dacB 3079422 dacB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanyl-D-alanine carboxypeptidase YP_096594.1 2921870 R 272624 CDS YP_096595.1 52842796 3079211 complement(2923755..2924546) 1 NC_002942.5 chromosome partitioning protein ParB 2924546 spoOJ 3079211 spoOJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome partitioning protein ParB YP_096595.1 2923755 R 272624 CDS YP_096596.1 52842797 3079223 complement(2924663..2925160) 1 NC_002942.5 hypothetical protein 2925160 3079223 lpg2591 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096596.1 2924663 R 272624 CDS YP_096597.1 52842798 3079428 complement(2925333..2926082) 1 NC_002942.5 hypothetical protein 2926082 3079428 lpg2592 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096597.1 2925333 R 272624 CDS YP_096598.1 52842799 3079180 complement(2926079..2927362) 1 NC_002942.5 rRNA methyltransferase (SUN protein) 2927362 3079180 lpg2593 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rRNA methyltransferase (SUN protein) YP_096598.1 2926079 R 272624 CDS YP_096599.1 52842800 3079088 complement(2927359..2928303) 1 NC_002942.5 methionyl tRNA formyltransferase 2928303 fmt 3079088 fmt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionyl tRNA formyltransferase YP_096599.1 2927359 R 272624 CDS YP_096600.1 52842801 3079277 complement(2928300..2928812) 1 NC_002942.5 peptide deformylase 2928812 def 3079277 def Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptide deformylase YP_096600.1 2928300 R 272624 CDS YP_096601.1 52842802 3079458 2928906..2929943 1 NC_002942.5 signal peptide protein 2929943 3079458 lpg2596 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 signal peptide protein YP_096601.1 2928906 D 272624 CDS YP_096602.1 52842803 3079478 2929940..2931025 1 NC_002942.5 DNA processing protein DprA 2931025 3079478 lpg2597 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA processing protein DprA YP_096602.1 2929940 D 272624 CDS YP_096603.1 52842804 3079146 2931036..2931452 1 NC_002942.5 hypothetical protein 2931452 3079146 lpg2598 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096603.1 2931036 D 272624 CDS YP_096604.1 52842805 3079059 2931531..2933810 1 NC_002942.5 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 2933810 topA 3079059 topA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA topoisomerase I YP_096604.1 2931531 D 272624 CDS YP_096605.1 52842806 3079001 complement(2933912..2935885) 1 NC_002942.5 acyltransferase 2935885 3079001 lpg2600 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyltransferase YP_096605.1 2933912 R 272624 CDS YP_096606.1 52842807 3079359 complement(2936021..2936461) 1 NC_002942.5 hypothetical protein 2936461 3079359 lpg2601 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096606.1 2936021 R 272624 CDS YP_096607.1 52842808 3079319 2936592..2937014 1 NC_002942.5 hypothetical protein 2937014 3079319 lpg2602 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096607.1 2936592 D 272624 CDS YP_096608.1 52842809 3079227 2937032..2938336 1 NC_002942.5 hypothetical protein 2938336 3079227 lpg2603 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096608.1 2937032 D 272624 CDS YP_096609.1 52842810 3079239 2938631..2939434 1 NC_002942.5 hypothetical protein 2939434 3079239 lpg2604 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096609.1 2938631 D 272624 CDS YP_096610.1 52842811 3079147 complement(2939490..2939906) 1 NC_002942.5 hypothetical protein 2939906 3079147 lpg2605 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096610.1 2939490 R 272624 CDS YP_096611.1 52842812 3079190 complement(2940021..2940887) 1 NC_002942.5 glutamine amidotransferase 2940887 3079190 lpg2606 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine amidotransferase YP_096611.1 2940021 R 272624 CDS YP_096612.1 52842813 3079484 complement(2941026..2943062) 1 NC_002942.5 metallopeptidase PepO 2943062 pepO 3079484 pepO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 metallopeptidase PepO YP_096612.1 2941026 R 272624 CDS YP_096613.1 52842814 3079278 complement(2943206..2944120) 1 NC_002942.5 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2944120 lpxC 3079278 lpxC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_096613.1 2943206 R 272624 CDS YP_096614.1 52842815 3079291 complement(2944368..2945564) 1 NC_002942.5 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2945564 ftsZ 3079291 ftsZ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein FtsZ YP_096614.1 2944368 R 272624 CDS YP_096615.1 52842816 3079352 complement(2945759..2947021) 1 NC_002942.5 ATP-binding cell division protein FtsA 2947021 ftsA 3079352 ftsA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-binding cell division protein FtsA YP_096615.1 2945759 R 272624 CDS YP_096616.1 52842817 3079173 complement(2946997..2947716) 1 NC_002942.5 cell division protein FtsQ 2947716 ftsQ 3079173 ftsQ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein FtsQ YP_096616.1 2946997 R 272624 CDS YP_096617.1 52842818 3079243 complement(2947732..2948838) 1 NC_002942.5 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 2948838 ddl 3079243 ddl Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-alanyl-alanine synthetase A YP_096617.1 2947732 R 272624 CDS YP_096618.1 52842819 3079370 complement(2948810..2949748) 1 NC_002942.5 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 2949748 murB 3079370 murB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylenolpyruvoylglucosamine reductase YP_096618.1 2948810 R 272624 CDS YP_096619.1 52842820 3079186 complement(2949745..2951154) 1 NC_002942.5 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2951154 murC 3079186 murC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramate--L-alanine ligase YP_096619.1 2949745 R 272624 CDS YP_096620.1 52842821 3079351 complement(2951164..2952348) 1 NC_002942.5 cell division protein FtsW 2952348 ftsW 3079351 ftsW Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein FtsW YP_096620.1 2951164 R 272624 CDS YP_096621.1 52842822 3079308 complement(2952345..2953688) 1 NC_002942.5 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2953688 murD 3079308 murD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_096621.1 2952345 R 272624 CDS YP_096622.1 52842823 3079062 complement(2953702..2954820) 1 NC_002942.5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2954820 mraY 3079062 mraY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_096622.1 2953702 R 272624 CDS YP_096623.1 52842824 3079365 complement(2954902..2956287) 1 NC_002942.5 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 2956287 murF 3079365 murF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_096623.1 2954902 R 272624 CDS YP_096624.1 52842825 3079086 complement(2956480..2957259) 1 NC_002942.5 cell division protein ZipA 2957259 3079086 lpg2619 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein ZipA YP_096624.1 2956480 R 272624 CDS YP_096625.1 52842826 3079112 complement(2957264..2960758) 1 NC_002942.5 chromosome segregation protein SMC 2960758 3079112 lpg2620 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome segregation protein SMC YP_096625.1 2957264 R 272624 CDS YP_096626.1 52842827 3079353 2960933..2961613 1 NC_002942.5 acid phosphatase, class B 2961613 3079353 lpg2621 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acid phosphatase, class B YP_096626.1 2960933 D 272624 CDS YP_096627.1 52842828 3079275 complement(2961715..2962776) 1 NC_002942.5 hypothetical protein 2962776 3079275 lpg2622 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096627.1 2961715 R 272624 CDS YP_096628.1 52842829 3079289 2963086..2963898 1 NC_002942.5 transmembrane protein 2963898 3079289 lpg2623 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096628.1 2963086 D 272624 CDS YP_096629.1 52842830 3079185 complement(2963973..2964455) 1 NC_002942.5 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 2964455 greA 3079185 greA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription elongation factor GreA YP_096629.1 2963973 R 272624 CDS YP_096630.1 52842831 3079314 complement(2964464..2967667) 1 NC_002942.5 carbamoyl phosphate synthase, large subunit 2967667 carB 3079314 carB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carbamoyl phosphate synthase, large subunit YP_096630.1 2964464 R 272624 CDS YP_096631.1 52842832 3079488 complement(2967794..2968066) 1 NC_002942.5 hypothetical protein 2968066 3079488 lpg2626 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096631.1 2967794 R 272624 CDS YP_096632.1 52842833 3079404 2968179..2969360 1 NC_002942.5 hypothetical protein 2969360 3079404 lpg2627 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096632.1 2968179 D 272624 CDS YP_096633.1 52842834 3079045 complement(2969395..2970147) 1 NC_002942.5 hypothetical protein 2970147 3079045 lpg2628 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096633.1 2969395 R 272624 CDS YP_096634.1 52842835 3079201 complement(2970147..2971217) 1 NC_002942.5 permease 2971217 3079201 lpg2629 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 permease YP_096634.1 2970147 R 272624 CDS YP_096635.1 52842836 3079206 complement(2971214..2972215) 1 NC_002942.5 permease 2972215 3079206 lpg2630 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 permease YP_096635.1 2971214 R 272624 CDS YP_096636.1 52842837 3079479 2972463..2973947 1 NC_002942.5 aminopeptidase 2973947 pepA 3079479 pepA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminopeptidase YP_096636.1 2972463 D 272624 CDS YP_096637.1 52842838 3079456 2973928..2974362 1 NC_002942.5 DNA polymerase III subunit chi 2974362 holC 3079456 holC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III subunit chi YP_096637.1 2973928 D 272624 CDS YP_096638.1 52842839 3079108 complement(2974501..2974818) 1 NC_002942.5 hypothetical protein 2974818 3079108 lpg2633 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096638.1 2974501 R 272624 CDS YP_096639.1 52842840 3079099 complement(2974841..2976205) 1 NC_002942.5 leucine aminopeptidase 2976205 3079099 lpg2634 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 leucine aminopeptidase YP_096639.1 2974841 R 272624 CDS YP_096640.1 52842841 3079210 complement(2976210..2977781) 1 NC_002942.5 virulence factor MviN 2977781 mviN 3079210 mviN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 virulence factor MviN YP_096640.1 2976210 R 272624 CDS YP_096641.1 52842842 3079159 2978139..2978405 1 NC_002942.5 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2978405 rpsT 3079159 rpsT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S20 YP_096641.1 2978139 D 272624 CDS YP_096642.1 52842843 3079349 complement(2978466..2979677) 1 NC_002942.5 hypothetical protein 2979677 3079349 lpg2637 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096642.1 2978466 R 272624 CDS YP_096643.1 52842844 3079165 complement(2980029..2981411) 1 NC_002942.5 hypothetical protein 2981411 3079165 lpg2638 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096643.1 2980029 R 272624 CDS YP_096644.1 52842845 3079177 complement(2981818..2985420) 1 NC_002942.5 enhanced entry protein EnhC 2985420 enhC 3079177 enhC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhC YP_096644.1 2981818 R 272624 CDS YP_096645.1 52842846 3079118 complement(2985447..2986013) 1 NC_002942.5 enhanced entry protein EnhB 2986013 enhB 3079118 enhB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhB YP_096645.1 2985447 R 272624 CDS YP_096646.1 52842847 3079172 complement(2986010..2986732) 1 NC_002942.5 enhanced entry protein EnhA 2986732 enhA 3079172 enhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 enhanced entry protein EnhA YP_096646.1 2986010 R 272624 CDS YP_096647.1 52842848 3079904 2986905..2989412 1 NC_002942.5 sensory box/GGDEF family protein 2989412 3079904 lpg2642 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box/GGDEF family protein YP_096647.1 2986905 D 272624 CDS YP_096648.1 52842849 3079331 2989553..2990212 1 NC_002942.5 hypothetical protein 2990212 3079331 lpg2643 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096648.1 2989553 D 272624 CDS YP_096649.1 52842850 3079101 2990380..2991861 1 NC_002942.5 hypothetical protein 2991861 sclB 3079101 sclB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096649.1 2990380 D 272624 CDS YP_096650.1 52842851 3079148 complement(2991885..2993741) 1 NC_002942.5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2993741 uvrC 3079148 uvrC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 excinuclease ABC subunit C YP_096650.1 2991885 R 272624 CDS YP_096651.1 52842852 3079109 complement(2993753..2994430) 1 NC_002942.5 response regulator GacA 2994430 gacA 3079109 gacA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 response regulator GacA YP_096651.1 2993753 R 272624 CDS YP_096652.2 224458591 3079270 complement(2994537..2995355) 1 NC_002942.5 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin; phenylalanine 4-monooxygenase 2995355 phhA 3079270 phhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phenylalanine 4-monooxygenase YP_096652.2 2994537 R 272624 CDS YP_096653.1 52842854 3079229 2995794..2996891 1 NC_002942.5 competence damage inducible protein CinA 2996891 cinA 3079229 cinA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 competence damage inducible protein CinA YP_096653.1 2995794 D 272624 CDS YP_096654.2 161723242 3079176 complement(2996850..2997875) 1 NC_002942.5 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2997875 obgE 3079176 obgE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTPase ObgE YP_096654.2 2996850 R 272624 CDS YP_096655.1 52842856 3079234 complement(2998090..2998368) 1 NC_002942.5 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2998368 rpmA 3079234 rpmA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L27 YP_096655.1 2998090 R 272624 CDS YP_096656.1 52842857 3079145 complement(2998381..2998692) 1 NC_002942.5 50S ribosomal protein L21 2998692 rplU 3079145 rplU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L21 YP_096656.1 2998381 R 272624 CDS YP_096657.1 52842858 3079194 2998935..2999594 1 NC_002942.5 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2999594 3079194 lpg2652 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L25 YP_096657.1 2998935 D 272624 CDS YP_096658.1 52842859 3079075 2999713..3000282 1 NC_002942.5 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 3000282 pth 3079075 pth Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidyl-tRNA hydrolase YP_096658.1 2999713 D 272624 CDS YP_096659.1 52842860 3079232 3000301..3001392 1 NC_002942.5 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3001392 3079232 lpg2654 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP-dependent nucleic acid-binding protein EngD YP_096659.1 3000301 D 272624 CDS YP_096660.1 52842861 3079350 3001753..3002868 1 NC_002942.5 sensory box protein 3002868 3079350 lpg2655 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensory box protein YP_096660.1 3001753 D 272624 CDS YP_096661.1 52842862 3079309 3003002..3003970 1 NC_002942.5 octaprenyl diphosphate synthase IspB 3003970 3079309 lpg2656 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 octaprenyl diphosphate synthase IspB YP_096661.1 3003002 D 272624 CDS YP_096662.1 52842863 3079487 complement(3004193..3006448) 1 NC_002942.5 ferrous iron transport protein B 3006448 feoB 3079487 feoB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ferrous iron transport protein B YP_096662.1 3004193 R 272624 CDS YP_096663.1 52842864 3079179 complement(3006445..3006672) 1 NC_002942.5 ferrous iron transporter A 3006672 feoA 3079179 feoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ferrous iron transporter A YP_096663.1 3006445 R 272624 CDS YP_096664.1 52842865 3079225 complement(3006761..3007852) 1 NC_002942.5 ATPase N2B (nucleotide (GTP) binding protein) 3007852 3079225 lpg2659 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATPase N2B (nucleotide (GTP) binding protein) YP_096664.1 3006761 R 272624 CDS YP_096665.1 52842866 3079237 complement(3007840..3008502) 1 NC_002942.5 transmembrane protein 3008502 3079237 lpg2660 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transmembrane protein YP_096665.1 3007840 R 272624 CDS YP_096666.1 52842867 3079219 3008661..3009527 1 NC_002942.5 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3009527 panB 3079219 panB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_096666.1 3008661 D 272624 CDS YP_096667.1 52842868 3079377 3009539..3010297 1 NC_002942.5 pantoate-beta-alanine ligase 3010297 panC 3079377 panC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pantoate-beta-alanine ligase YP_096667.1 3009539 D 272624 CDS YP_096668.1 52842869 3079369 3010294..3010827 1 NC_002942.5 hypothetical protein 3010827 3079369 lpg2663 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096668.1 3010294 D 272624 CDS YP_096669.1 52842870 3079368 complement(3010830..3012245) 1 NC_002942.5 biotin carboxylase; with subunit B, the carboxyltansferase/biotincarboxyl carrier subunit catalyzes the formation of oxaloacetate from pyruvate; pyruvate carboxylase subunit A 3012245 3079368 lpg2664 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pyruvate carboxylase subunit A YP_096669.1 3010830 R 272624 CDS YP_096670.1 52842871 3079224 complement(3012238..3012954) 1 NC_002942.5 dienelactone hydrolase 3012954 3079224 lpg2665 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dienelactone hydrolase YP_096670.1 3012238 R 272624 CDS YP_096671.1 52842872 3079110 3013221..3014102 1 NC_002942.5 hydrolase 3014102 3079110 lpg2666 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hydrolase YP_096671.1 3013221 D 272624 CDS YP_096672.1 52842873 3079454 complement(3014236..3015114) 1 NC_002942.5 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3015114 rpoH 3079454 rpoH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 RNA polymerase factor sigma-32 YP_096672.1 3014236 R 272624 CDS YP_096673.1 52842874 3079364 complement(3015387..3016316) 1 NC_002942.5 cell division ATP transporter FtsX 3016316 ftsX 3079364 ftsX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division ATP transporter FtsX YP_096673.1 3015387 R 272624 CDS YP_096674.1 52842875 3079126 complement(3016310..3016996) 1 NC_002942.5 hypothetical protein 3016996 ftsE 3079126 ftsE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096674.1 3016310 R 272624 CDS YP_096675.1 52842876 3079193 complement(3016947..3018053) 1 NC_002942.5 cell division membrane protein FtsY 3018053 ftsY 3079193 ftsY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division membrane protein FtsY YP_096675.1 3016947 R 272624 CDS YP_096676.1 52842877 3079294 3018077..3019402 1 NC_002942.5 zinc protease 3019402 3079294 lpg2671 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc protease YP_096676.1 3018077 D 272624 CDS YP_096677.1 52842878 3079471 3019399..3020703 1 NC_002942.5 zinc protease 3020703 3079471 lpg2672 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc protease YP_096677.1 3019399 D 272624 CDS YP_096678.1 52842879 3079208 3020700..3021245 1 NC_002942.5 N-6 adenine-specific DNA methylase 3021245 3079208 lpg2673 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-6 adenine-specific DNA methylase YP_096678.1 3020700 D 272624 CDS YP_096679.1 52842880 3079141 3021320..3021811 1 NC_002942.5 lipoprotein DotD 3021811 dotD 3079141 dotD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein DotD YP_096679.1 3021320 D 272624 CDS YP_096680.1 52842881 3079340 3021792..3022703 1 NC_002942.5 DotC 3022703 dotC 3079340 dotC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DotC YP_096680.1 3021792 D 272624 CDS YP_096681.1 52842882 3079449 3022673..3023836 1 NC_002942.5 ATPase 3023836 dotB 3079449 dotB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATPase YP_096681.1 3022673 D 272624 CDS YP_096682.1 52842883 3079167 3023919..3025646 1 NC_002942.5 5'-nucleotidase 3025646 3079167 lpg2677 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 5'-nucleotidase YP_096682.1 3023919 D 272624 CDS YP_096683.1 52842884 3079399 complement(3025688..3026485) 1 NC_002942.5 hypothetical protein 3026485 3079399 lpg2678 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096683.1 3025688 R 272624 CDS YP_096684.1 52842885 3079302 complement(3026515..3027459) 1 NC_002942.5 D-isomer specific 2-hydroxyacid dehydrogenase 3027459 3079302 lpg2679 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 D-isomer specific 2-hydroxyacid dehydrogenase YP_096684.1 3026515 R 272624 CDS YP_096685.1 52842886 3079335 3027690..3028718 1 NC_002942.5 UDP-N-acetylmuramyl tripeptide synthase 3028718 murE3 3079335 murE3 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylmuramyl tripeptide synthase YP_096685.1 3027690 D 272624 CDS YP_096686.1 52842887 3079169 3028993..3029880 1 NC_002942.5 4-hydroxy-2-oxovalerate aldolase 3029880 3079169 lpg2681 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 4-hydroxy-2-oxovalerate aldolase YP_096686.1 3028993 D 272624 CDS YP_096687.1 52842888 3079116 3030019..3030726 1 NC_002942.5 hypothetical protein 3030726 3079116 lpg2682 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096687.1 3030019 D 272624 CDS YP_096688.1 52842889 3079431 3030713..3032560 1 NC_002942.5 DlpA protein 3032560 3079431 lpg2683 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DlpA protein YP_096688.1 3030713 D 272624 CDS YP_096689.1 52842890 3079430 3032560..3033420 1 NC_002942.5 hypothetical protein 3033420 3079430 lpg2684 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096689.1 3032560 D 272624 CDS YP_096690.1 52842891 3079429 complement(3033585..3034331) 1 NC_002942.5 dienelactone hydrolase 3034331 3079429 lpg2685 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dienelactone hydrolase YP_096690.1 3033585 R 272624 CDS YP_096691.1 52842892 3079451 complement(3034433..3037579) 1 NC_002942.5 defect in organelle trafficking protein DotA 3037579 dotA 3079451 dotA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 defect in organelle trafficking protein DotA YP_096691.1 3034433 R 272624 CDS YP_096692.1 52842893 3079199 complement(3037576..3038031) 1 NC_002942.5 intracellular multiplication protein IcmV 3038031 icmV 3079199 icmV Legionella pneumophila subsp. pneumophila str. Philadelphia 1 intracellular multiplication protein IcmV YP_096692.1 3037576 R 272624 CDS YP_096693.1 52842894 3079202 3038144..3038599 1 NC_002942.5 intracellular multiplication protein IcmW 3038599 icmW 3079202 icmW Legionella pneumophila subsp. pneumophila str. Philadelphia 1 intracellular multiplication protein IcmW YP_096693.1 3038144 D 272624 CDS YP_096694.1 52842895 3079093 3038599..3039999 1 NC_002942.5 intracellular multiplication protein IcmX 3039999 icmX 3079093 icmX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 intracellular multiplication protein IcmX YP_096694.1 3038599 D 272624 CDS YP_096695.1 52842896 3079463 complement(3040006..3041637) 1 NC_002942.5 protein LphB 3041637 lphB 3079463 lphB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein LphB YP_096695.1 3040006 R 272624 CDS YP_096696.1 52842897 3079419 3041997..3044540 1 NC_002942.5 cation transporting ATPase PacS 3044540 3079419 lpg2691 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation transporting ATPase PacS YP_096696.1 3041997 D 272624 CDS YP_096697.1 52842898 3079483 3044791..3045321 1 NC_002942.5 hypothetical protein 3045321 3079483 lpg2692 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096697.1 3044791 D 272624 CDS YP_096698.1 52842899 3079304 complement(3045394..3046194) 1 NC_002942.5 SnoK-like protein 3046194 3079304 lpg2693 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SnoK-like protein YP_096698.1 3045394 R 272624 CDS YP_096699.1 52842900 3079055 complement(3046318..3047175) 1 NC_002942.5 phytanoyl-CoA dioxygenase 3047175 legD1 3079055 legD1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phytanoyl-CoA dioxygenase YP_096699.1 3046318 R 272624 CDS YP_096700.1 52842901 3079212 complement(3047264..3048325) 1 NC_002942.5 heptosyl transferase glycosyltransferase 9 protein 3048325 3079212 lpg2695 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heptosyl transferase glycosyltransferase 9 protein YP_096700.1 3047264 R 272624 CDS YP_096701.1 52842902 3079360 complement(3048511..3049476) 1 NC_002942.5 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 3049476 miaA 3079360 miaA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA delta(2)-isopentenylpyrophosphate transferase YP_096701.1 3048511 R 272624 CDS YP_096702.1 52842903 3079316 complement(3049445..3051175) 1 NC_002942.5 DNA mismatch repair protein MutL 3051175 mutL 3079316 mutL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA mismatch repair protein MutL YP_096702.1 3049445 R 272624 CDS YP_096703.1 52842904 3079072 complement(3051166..3052596) 1 NC_002942.5 N-acetylmuramoyl-L-alanine amidase 3052596 amiB 3079072 amiB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 N-acetylmuramoyl-L-alanine amidase YP_096703.1 3051166 R 272624 CDS YP_096704.1 52842905 3079241 complement(3052593..3053075) 1 NC_002942.5 hypothetical protein 3053075 3079241 lpg2699 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096704.1 3052593 R 272624 CDS YP_096705.1 52842906 3079070 complement(3053201..3054682) 1 NC_002942.5 sugar kinase 3054682 3079070 lpg2700 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sugar kinase YP_096705.1 3053201 R 272624 CDS YP_096706.1 52842907 3079358 complement(3054810..3055205) 1 NC_002942.5 ClpXP protease specificity-enhancing factor 3055205 sspB 3079358 sspB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ClpXP protease specificity-enhancing factor YP_096706.1 3054810 R 272624 CDS YP_096707.1 52842908 3079281 complement(3055208..3055828) 1 NC_002942.5 stringent starvation protein A 3055828 sspA 3079281 sspA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stringent starvation protein A YP_096707.1 3055208 R 272624 CDS YP_096708.1 52842909 3079261 complement(3056079..3056819) 1 NC_002942.5 ubiquinol-cytochrome c reductase, cytochrome c1 3056819 3079261 lpg2703 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinol-cytochrome c reductase, cytochrome c1 YP_096708.1 3056079 R 272624 CDS YP_096709.1 52842910 3079056 complement(3056816..3058030) 1 NC_002942.5 ubiquinol-cytochrome c reductase, cytochrome b 3058030 petB 3079056 petB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinol-cytochrome c reductase, cytochrome b YP_096709.1 3056816 R 272624 CDS YP_096710.1 52842911 3079048 complement(3058041..3058667) 1 NC_002942.5 ubiquinol-cytochrome c reductase, iron-sulfur subunit 3058667 petA 3079048 petA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_096710.1 3058041 R 272624 CDS YP_096711.1 52842912 3079083 complement(3058832..3059263) 1 NC_002942.5 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3059263 rpsI 3079083 rpsI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S9 YP_096711.1 3058832 R 272624 CDS YP_096712.2 161723241 3079392 complement(3059269..3059703) 1 NC_002942.5 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3059703 rplM 3079392 rplM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L13 YP_096712.2 3059269 R 272624 CDS YP_096713.1 52842914 3079216 complement(3060042..3060257) 1 NC_002942.5 (2Fe-2S)-binding protein 3060257 3079216 lpg2708 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (2Fe-2S)-binding protein YP_096713.1 3060042 R 272624 CDS YP_096714.1 52842915 3079171 complement(3060361..3060660) 1 NC_002942.5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 3060660 ihfA 3079171 ihfA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 integration host factor subunit alpha YP_096714.1 3060361 R 272624 CDS YP_096715.1 52842916 3079170 complement(3060657..3063038) 1 NC_002942.5 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 3063038 pheT 3079170 pheT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phenylalanyl-tRNA synthetase subunit beta YP_096715.1 3060657 R 272624 CDS YP_096716.1 52842917 3079427 complement(3063296..3064324) 1 NC_002942.5 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 3064324 pheS 3079427 pheS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phenylalanyl-tRNA synthetase subunit alpha YP_096716.1 3063296 R 272624 CDS YP_096717.1 52842918 3079096 complement(3064449..3064808) 1 NC_002942.5 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 3064808 rplT 3079096 rplT Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L20 YP_096717.1 3064449 R 272624 CDS YP_096718.1 52842919 3079476 complement(3065045..3065434) 1 NC_002942.5 translational initiation factor IF-3 3065434 infC 3079476 infC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 translational initiation factor IF-3 YP_096718.1 3065045 R 272624 CDS YP_096719.1 52842920 3079477 complement(3065606..3067546) 1 NC_002942.5 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 3067546 thrS 3079477 thrS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 threonyl-tRNA synthetase YP_096719.1 3065606 R 272624 CDS YP_096720.1 52842921 3079252 3068032..3068319 1 NC_002942.5 hypothetical protein 3068319 3079252 lpg2716 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096720.1 3068032 D 272624 CDS YP_096721.1 52842922 3079182 3068642..3069127 1 NC_002942.5 hypothetical protein 3069127 3079182 lpg2717 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096721.1 3068642 D 272624 CDS YP_096722.1 52842923 3079528 complement(3069837..3071399) 1 NC_002942.5 hypothetical protein 3071399 3079528 lpg2718 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096722.1 3069837 R 272624 CDS YP_096723.1 52842924 3079317 3071680..3072831 1 NC_002942.5 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 3072831 3079317 lpg2719 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 carboxylate-amine ligase YP_096723.1 3071680 D 272624 CDS YP_096724.1 52842925 3079510 3072810..3073841 1 NC_002942.5 cNMP binding domain-containing protein 3073841 legN 3079510 legN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cNMP binding domain-containing protein YP_096724.1 3072810 D 272624 CDS YP_096725.1 52842926 3079282 3073978..3074766 1 NC_002942.5 glutamine amidotransferase 3074766 3079282 lpg2721 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutamine amidotransferase YP_096725.1 3073978 D 272624 CDS YP_096726.1 52842927 3079549 complement(3074894..3075970) 1 NC_002942.5 Oye family NADH-dependent flavin oxidoreductase 3075970 3079549 lpg2722 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Oye family NADH-dependent flavin oxidoreductase YP_096726.1 3074894 R 272624 CDS YP_096727.1 52842928 3079328 complement(3076021..3076320) 1 NC_002942.5 transcriptional regulator 3076320 3079328 lpg2723 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcriptional regulator YP_096727.1 3076021 R 272624 CDS YP_096728.1 52842929 3078943 complement(3076573..3076917) 1 NC_002942.5 hypothetical protein 3076917 3078943 lpg2724 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096728.1 3076573 R 272624 CDS YP_096729.1 52842930 3079551 3077034..3077663 1 NC_002942.5 hypothetical protein 3077663 3079551 lpg2725 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096729.1 3077034 D 272624 CDS YP_096730.1 52842931 3079240 complement(3077871..3078365) 1 NC_002942.5 peptidylprolyl cis-trans isomerase B (cyclophilin-type) Lcy 3078365 ppiB 3079240 ppiB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peptidylprolyl cis-trans isomerase B (cyclophilin-type) Lcy YP_096730.1 3077871 R 272624 CDS YP_096731.1 52842932 3078944 complement(3078392..3079558) 1 NC_002942.5 queuine/archaeosine tRNA-ribosyltransferase 3079558 tgt 3078944 tgt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 queuine/archaeosine tRNA-ribosyltransferase YP_096731.1 3078392 R 272624 CDS YP_096732.1 52842933 3079508 complement(3079540..3079710) 1 NC_002942.5 hypothetical protein 3079710 3079508 lpg2728 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096732.1 3079540 R 272624 CDS YP_096733.1 52842934 3079526 complement(3080093..3080557) 1 NC_002942.5 cytochrome c5 3080557 cycB 3079526 cycB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c5 YP_096733.1 3080093 R 272624 CDS YP_096734.1 52842935 3079491 3080710..3081960 1 NC_002942.5 hypothetical protein 3081960 3079491 lpg2731 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096734.1 3080710 D 272624 CDS YP_096735.1 52842936 3079555 complement(3082042..3083067) 1 NC_002942.5 (two component) response regulator 3083067 3079555 lpg2732 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (two component) response regulator YP_096735.1 3082042 R 272624 CDS YP_096736.1 52842937 3079556 3083349..3083912 1 NC_002942.5 hypothetical protein 3083912 3079556 lpg2733 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096736.1 3083349 D 272624 CDS YP_096737.1 52842938 3079560 complement(3084000..3085289) 1 NC_002942.5 sensor protein LuxN 3085289 3079560 lpg2734 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sensor protein LuxN YP_096737.1 3084000 R 272624 CDS YP_096738.1 52842939 3079585 3085645..3086610 1 NC_002942.5 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 3086610 hemC 3079585 hemC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 porphobilinogen deaminase YP_096738.1 3085645 D 272624 CDS YP_096739.1 52842940 3079517 3086607..3087359 1 NC_002942.5 uroporphyrinogen III methylase 3087359 3079517 lpg2736 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uroporphyrinogen III methylase YP_096739.1 3086607 D 272624 CDS YP_096740.1 52842941 3079536 3087363..3088487 1 NC_002942.5 uroporphyrinogen III methylase 3088487 3079536 lpg2737 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 uroporphyrinogen III methylase YP_096740.1 3087363 D 272624 CDS YP_096741.1 52842942 3079530 3088490..3089677 1 NC_002942.5 protoporphyrinogen oxidase 3089677 hemY 3079530 hemY Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protoporphyrinogen oxidase YP_096741.1 3088490 D 272624 CDS YP_096742.1 52842943 3079539 complement(3089813..3090736) 1 NC_002942.5 cation efflux system protein 3090736 3079539 lpg2739 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cation efflux system protein YP_096742.1 3089813 R 272624 CDS YP_096743.1 52842944 3079563 complement(3090733..3091395) 1 NC_002942.5 hypothetical protein 3091395 3079563 lpg2740 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096743.1 3090733 R 272624 CDS YP_096744.1 52842945 3079545 complement(3091385..3091948) 1 NC_002942.5 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 3091948 orn 3079545 orn Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oligoribonuclease YP_096744.1 3091385 R 272624 CDS YP_096745.2 161723240 3079535 complement(3091938..3093170) 1 NC_002942.5 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3093170 cca 3079535 cca Legionella pneumophila subsp. pneumophila str. Philadelphia 1 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_096745.2 3091938 R 272624 CDS YP_096746.1 52842947 3079538 3093233..3094210 1 NC_002942.5 EngC GTPase 3094210 3079538 lpg2743 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 EngC GTPase YP_096746.1 3093233 D 272624 CDS YP_096747.1 52842948 3079540 complement(3094245..3095414) 1 NC_002942.5 hypothetical protein 3095414 3079540 lpg2744 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096747.1 3094245 R 272624 CDS YP_096748.1 52842949 3079557 complement(3095575..3097542) 1 NC_002942.5 hypothetical protein 3097542 3079557 lpg2745 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096748.1 3095575 R 272624 CDS YP_096749.1 52842950 3079544 3098360..3098641 1 NC_002942.5 hypothetical protein 3098641 3079544 lpg2749 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096749.1 3098360 D 272624 CDS YP_096750.1 52842951 3079554 3098418..3098759 1 NC_002942.5 hypothetical protein 3098759 3079554 lpg2750 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096750.1 3098418 D 272624 CDS YP_096751.1 52842952 3079527 3099250..3099600 1 NC_002942.5 hypothetical protein 3099600 3079527 lpg2751 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096751.1 3099250 D 272624 CDS YP_096752.1 52842953 3079605 3103406..3105076 1 NC_002942.5 DNA polymerase III subunits gamma and tau 3105076 dnaZX 3079605 dnaZX Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA polymerase III subunits gamma and tau YP_096752.1 3103406 D 272624 CDS YP_096753.1 52842954 3079609 3105110..3105448 1 NC_002942.5 hypothetical protein 3105448 3079609 lpg2755 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096753.1 3105110 D 272624 CDS YP_096754.1 52842955 3079610 3105451..3106050 1 NC_002942.5 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 3106050 recR 3079610 recR Legionella pneumophila subsp. pneumophila str. Philadelphia 1 recombination protein RecR YP_096754.1 3105451 D 272624 CDS YP_096755.1 52842956 3079614 3106043..3106903 1 NC_002942.5 hypothetical protein 3106903 3079614 lpg2757 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096755.1 3106043 D 272624 CDS YP_096756.1 52842957 3079617 3106900..3108897 1 NC_002942.5 hypothetical protein 3108897 3079617 lpg2758 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096756.1 3106900 D 272624 CDS YP_096757.1 52842958 3079634 complement(3109134..3110618) 1 NC_002942.5 hypothetical protein 3110618 3079634 lpg2759 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096757.1 3109134 R 272624 CDS YP_096758.1 52842959 3079640 3110820..3111548 1 NC_002942.5 DNA-binding response regulator 3111548 3079640 lpg2760 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA-binding response regulator YP_096758.1 3110820 D 272624 CDS YP_096759.1 52842960 3079498 complement(3111771..3112433) 1 NC_002942.5 hypothetical protein 3112433 3079498 lpg2761 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096759.1 3111771 R 272624 CDS YP_096760.1 52842961 3079571 complement(3112690..3113406) 1 NC_002942.5 hypothetical protein 3113406 3079571 lpg2762 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096760.1 3112690 R 272624 CDS YP_096761.1 52842962 3079584 complement(3113646..3114911) 1 NC_002942.5 Mg2+ and Co2+ transporter CorB, hemolysin 3114911 3079584 lpg2763 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Mg2+ and Co2+ transporter CorB, hemolysin YP_096761.1 3113646 R 272624 CDS YP_096762.1 52842963 3079619 complement(3115061..3115597) 1 NC_002942.5 inorganic pyrophosphatase 3115597 ppa 3079619 ppa Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inorganic pyrophosphatase YP_096762.1 3115061 R 272624 CDS YP_096763.1 52842964 3079567 3115727..3116068 1 NC_002942.5 hypothetical protein 3116068 hit 3079567 hit Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096763.1 3115727 D 272624 CDS YP_096764.1 52842965 3079543 3116053..3116619 1 NC_002942.5 GTP cyclohydrolase I 3116619 folE2 3079543 folE2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 GTP cyclohydrolase I YP_096764.1 3116053 D 272624 CDS YP_096765.1 52842966 3079588 complement(3116678..3117769) 1 NC_002942.5 hypothetical protein 3117769 3079588 lpg2767 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096765.1 3116678 R 272624 CDS YP_096766.1 52842967 3079599 complement(3117904..3120093) 1 NC_002942.5 polynucleotide phosphorylase 3120093 pnp 3079599 pnp Legionella pneumophila subsp. pneumophila str. Philadelphia 1 polynucleotide phosphorylase YP_096766.1 3117904 R 272624 CDS YP_096767.1 52842968 3079678 complement(3120208..3120483) 1 NC_002942.5 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3120483 rpsO 3079678 rpsO Legionella pneumophila subsp. pneumophila str. Philadelphia 1 30S ribosomal protein S15 YP_096767.1 3120208 R 272624 CDS YP_096768.1 52842969 3079695 complement(3120631..3121557) 1 NC_002942.5 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3121557 truB 3079695 truB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA pseudouridine synthase B YP_096768.1 3120631 R 272624 CDS YP_096769.1 52842970 3079713 complement(3121529..3121900) 1 NC_002942.5 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3121900 rbfA 3079713 rbfA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosome-binding factor A YP_096769.1 3121529 R 272624 CDS YP_096770.1 52842971 3079753 complement(3121904..3124510) 1 NC_002942.5 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3124510 infB 3079753 infB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 translation initiation factor IF-2 YP_096770.1 3121904 R 272624 CDS YP_096771.1 52842972 3079756 complement(3124599..3126077) 1 NC_002942.5 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3126077 nusA 3079756 nusA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription elongation factor NusA YP_096771.1 3124599 R 272624 CDS YP_096772.1 52842973 3079760 complement(3126089..3126532) 1 NC_002942.5 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3126532 3079760 lpg2774 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096772.1 3126089 R 272624 CDS YP_096773.1 52842974 3079820 complement(3126788..3128260) 1 NC_002942.5 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 3128260 nuoN 3079820 nuoN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit N YP_096773.1 3126788 R 272624 CDS YP_096774.1 52842975 3079837 complement(3128284..3129789) 1 NC_002942.5 NADH dehydrogenase I subunit M 3129789 nuoM 3079837 nuoM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit M YP_096774.1 3128284 R 272624 CDS YP_096775.1 52842976 3079859 complement(3129805..3131778) 1 NC_002942.5 NADH dehydrogenase I subunit L 3131778 nuoL 3079859 nuoL Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit L YP_096775.1 3129805 R 272624 CDS YP_096776.1 52842977 3079878 complement(3131783..3132088) 1 NC_002942.5 NADH dehydrogenase I subunit K 3132088 nuoK 3079878 nuoK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit K YP_096776.1 3131783 R 272624 CDS YP_096777.1 52842978 3079887 complement(3132106..3132765) 1 NC_002942.5 NADH dehydrogenase I subunit J 3132765 nuoJ 3079887 nuoJ Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit J YP_096777.1 3132106 R 272624 CDS YP_096778.1 52842979 3079899 complement(3132777..3133277) 1 NC_002942.5 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 3133277 nuoI 3079899 nuoI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit I YP_096778.1 3132777 R 272624 CDS YP_096779.1 52842980 3079953 complement(3133296..3134318) 1 NC_002942.5 NADH dehydrogenase I subunit H 3134318 nuoH 3079953 nuoH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit H YP_096779.1 3133296 R 272624 CDS YP_096780.1 52842981 3079306 complement(3134331..3136682) 1 NC_002942.5 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 3136682 nuoG 3079306 nuoG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit G YP_096780.1 3134331 R 272624 CDS YP_096781.1 52842982 3079546 complement(3136699..3137985) 1 NC_002942.5 NADH dehydrogenase I subunit F 3137985 nuoF 3079546 nuoF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit F YP_096781.1 3136699 R 272624 CDS YP_096782.1 52842983 3079564 complement(3137995..3138498) 1 NC_002942.5 NADH dehydrogenase I subunit E 3138498 3079564 lpg2785 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit E YP_096782.1 3137995 R 272624 CDS YP_096783.1 52842984 3079492 complement(3138559..3139827) 1 NC_002942.5 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 3139827 nuoD 3079492 nuoD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit D YP_096783.1 3138559 R 272624 CDS YP_096784.1 52842985 3079637 complement(3139805..3140488) 1 NC_002942.5 NADH dehydrogenase I subunit C 3140488 nuoC 3079637 nuoC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit C YP_096784.1 3139805 R 272624 CDS YP_096785.1 52842986 3079672 complement(3140511..3140987) 1 NC_002942.5 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3140987 nuoB2 3079672 nuoB2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase subunit B YP_096785.1 3140511 R 272624 CDS YP_096786.1 52842987 3079601 complement(3141237..3141593) 1 NC_002942.5 NADH dehydrogenase I subunit A 3141593 nuoA 3079601 nuoA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 NADH dehydrogenase I subunit A YP_096786.1 3141237 R 272624 CDS YP_096787.1 52842988 3079650 complement(3141773..3142078) 1 NC_002942.5 preprotein translocase subunit SecG 3142078 secG 3079650 secG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 preprotein translocase subunit SecG YP_096787.1 3141773 R 272624 CDS YP_096788.1 52842989 3079582 complement(3142084..3142833) 1 NC_002942.5 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3142833 tpiA 3079582 tpiA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 triosephosphate isomerase YP_096788.1 3142084 R 272624 CDS YP_096789.1 52842990 3079644 3143077..3146532 1 NC_002942.5 LepA; interaptin 3146532 lepA 3079644 lepA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 interaptin YP_096789.1 3143077 D 272624 CDS YP_096790.1 52842991 3079807 complement(3146601..3147968) 1 NC_002942.5 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3147968 glmM 3079807 glmM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoglucosamine mutase YP_096790.1 3146601 R 272624 CDS YP_096791.1 52842992 3079709 complement(3148032..3148907) 1 NC_002942.5 7,8-dihydropteroate synthase 3148907 3079709 lpg2795 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 7,8-dihydropteroate synthase YP_096791.1 3148032 R 272624 CDS YP_096792.1 52842993 3079903 complement(3148940..3150859) 1 NC_002942.5 cell division protein FtsH 3150859 ftsH 3079903 ftsH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cell division protein FtsH YP_096792.1 3148940 R 272624 CDS YP_096793.1 52842994 3079762 complement(3150972..3151715) 1 NC_002942.5 ribosomal RNA large subunit methyltransferase J 3151715 3079762 lpg2797 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribosomal RNA large subunit methyltransferase J YP_096793.1 3150972 R 272624 CDS YP_096794.1 52842995 3079732 complement(3152012..3153988) 1 NC_002942.5 O-acetyltransferase 3153988 3079732 lpg2799 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 O-acetyltransferase YP_096794.1 3152012 R 272624 CDS YP_096795.1 52842996 3079705 3154174..3155901 1 NC_002942.5 siderophore biosynthetic protein, iron repressed gene FrgA 3155901 frgA 3079705 frgA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 siderophore biosynthetic protein, iron repressed gene FrgA YP_096795.1 3154174 D 272624 CDS YP_096796.1 52842997 3079872 3156161..3156715 1 NC_002942.5 phosphatidylglycerophosphate synthase 3156715 3079872 lpg2801 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidylglycerophosphate synthase YP_096796.1 3156161 D 272624 CDS YP_096797.1 52842998 3079927 3156673..3157410 1 NC_002942.5 chromosome replication initiator DnaA 3157410 3079927 lpg2802 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome replication initiator DnaA YP_096797.1 3156673 D 272624 CDS YP_096798.1 52842999 3079877 3157636..3158493 1 NC_002942.5 hypothetical protein 3158493 3079877 lpg2803 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096798.1 3157636 D 272624 CDS YP_096799.1 52843000 3079824 complement(3158378..3159784) 1 NC_002942.5 hypothetical protein 3159784 3079824 lpg2804 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096799.1 3158378 R 272624 CDS YP_096800.1 52843001 3079891 complement(3159890..3161392) 1 NC_002942.5 POT family peptide transport protein 3161392 yhiP 3079891 yhiP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 POT family peptide transport protein YP_096800.1 3159890 R 272624 CDS YP_096801.1 52843002 3079788 complement(3161460..3162842) 1 NC_002942.5 hypothetical protein 3162842 3079788 lpg2806 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096801.1 3161460 R 272624 CDS YP_096802.1 52843003 3079925 3162980..3164092 1 NC_002942.5 patatin family protein 3164092 3079925 lpg2807 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 patatin family protein YP_096802.1 3162980 D 272624 CDS YP_096803.1 52843004 3079934 complement(3164142..3164939) 1 NC_002942.5 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3164939 aroE 3079934 aroE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 shikimate 5-dehydrogenase YP_096803.1 3164142 R 272624 CDS YP_096804.1 52843005 3079819 complement(3165149..3167746) 1 NC_002942.5 aminopeptidase 3167746 pepN 3079819 pepN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminopeptidase YP_096804.1 3165149 R 272624 CDS YP_096805.1 52843006 3079813 3167838..3169844 1 NC_002942.5 serine protein kinase 3169844 prkA 3079813 prkA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine protein kinase YP_096805.1 3167838 D 272624 CDS YP_096806.1 52843007 3079948 3169983..3171263 1 NC_002942.5 hypothetical protein 3171263 3079948 lpg2811 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096806.1 3169983 D 272624 CDS YP_096807.1 52843008 3079513 3171260..3172783 1 NC_002942.5 SpoVR family protein 3172783 3079513 lpg2812 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SpoVR family protein YP_096807.1 3171260 D 272624 CDS YP_096808.1 52843009 3079577 3173075..3173935 1 NC_002942.5 VipE 3173935 vipE 3079577 vipE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 VipE YP_096808.1 3173075 D 272624 CDS YP_096809.1 52843010 3079676 complement(3174016..3175284) 1 NC_002942.5 aminopeptidase 3175284 3079676 lpg2814 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aminopeptidase YP_096809.1 3174016 R 272624 CDS YP_096810.1 52843011 3079946 3175334..3177385 1 NC_002942.5 hypothetical protein 3177385 3079946 lpg2815 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096810.1 3175334 D 272624 CDS YP_096811.1 52843012 3079645 complement(3177469..3179466) 1 NC_002942.5 ATP-dependent DNA helicase Rep 3179466 rep 3079645 rep Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP-dependent DNA helicase Rep YP_096811.1 3177469 R 272624 CDS YP_096812.1 52843013 3079855 3179864..3180727 1 NC_002942.5 heat shock protein 33, redox regulated chaperonin 3180727 yrfI 3079855 yrfI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 heat shock protein 33, redox regulated chaperonin YP_096812.1 3179864 D 272624 CDS YP_096813.1 52843014 3079722 complement(3180741..3181238) 1 NC_002942.5 hypothetical protein 3181238 3079722 lpg2818 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096813.1 3180741 R 272624 CDS YP_096814.1 52843015 3079726 complement(3181506..3182465) 1 NC_002942.5 tyrosine phosphatase II superfamily protein 3182465 3079726 lpg2819 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tyrosine phosphatase II superfamily protein YP_096814.1 3181506 R 272624 CDS YP_096815.1 52843016 3079612 3182643..3183653 1 NC_002942.5 aldo/keto reductase 3183653 3079612 lpg2820 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aldo/keto reductase YP_096815.1 3182643 D 272624 CDS YP_096816.1 52843017 3079873 3183761..3184573 1 NC_002942.5 sugar kinase 3184573 3079873 lpg2821 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sugar kinase YP_096816.1 3183761 D 272624 CDS YP_096817.1 52843018 3079591 3184685..3186511 1 NC_002942.5 virulence regulator BipA 3186511 bipA 3079591 bipA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 virulence regulator BipA YP_096817.1 3184685 D 272624 CDS YP_096818.1 52843019 3079810 3186518..3187405 1 NC_002942.5 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3187405 ppnK 3079810 ppnK Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inorganic polyphosphate/ATP-NAD kinase YP_096818.1 3186518 D 272624 CDS YP_096819.1 52843020 3079780 3187409..3189076 1 NC_002942.5 DNA repair protein RecN 3189076 recN 3079780 recN Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA repair protein RecN YP_096819.1 3187409 D 272624 CDS YP_096820.1 52843021 3079608 3189243..3189449 1 NC_002942.5 cold shock protein CspE 3189449 3079608 lpg2825 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock protein CspE YP_096820.1 3189243 D 272624 CDS YP_096821.1 52843022 3079945 complement(3189788..3191521) 1 NC_002942.5 hypothetical protein 3191521 3079945 lpg2826 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096821.1 3189788 R 272624 CDS YP_096822.1 52843023 3079714 3191867..3192844 1 NC_002942.5 hypothetical protein 3192844 3079714 lpg2827 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096822.1 3191867 D 272624 CDS YP_096823.1 52843024 3079853 3192992..3194248 1 NC_002942.5 hypothetical protein 3194248 3079853 lpg2828 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096823.1 3192992 D 272624 CDS YP_096824.1 52843025 3079718 complement(3194315..3200992) 1 NC_002942.5 protein SidH 3200992 sidH 3079718 sidH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protein SidH YP_096824.1 3194315 R 272624 CDS YP_096825.1 52843026 3079841 complement(3201113..3201853) 1 NC_002942.5 UBOX-containing protein 3201853 legU2 3079841 legU2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UBOX-containing protein YP_096825.1 3201113 R 272624 CDS YP_096826.1 52843027 3079886 3202105..3203970 1 NC_002942.5 VipD 3203970 vipD 3079886 vipD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 VipD YP_096826.1 3202105 D 272624 CDS YP_096827.1 52843028 3079838 complement(3204025..3205665) 1 NC_002942.5 hypothetical protein 3205665 3079838 lpg2832 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096827.1 3204025 R 272624 CDS YP_096828.1 52843029 3079778 complement(3205662..3206042) 1 NC_002942.5 acyl-CoA thioester hydrolase 3206042 yciA 3079778 yciA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acyl-CoA thioester hydrolase YP_096828.1 3205662 R 272624 CDS YP_096829.1 52843030 3079717 complement(3206045..3208414) 1 NC_002942.5 transcription accessory protein 3208414 3079717 lpg2834 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription accessory protein YP_096829.1 3206045 R 272624 CDS YP_096830.1 52843031 3079708 complement(3208538..3209203) 1 NC_002942.5 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase 3209203 tpm 3079708 tpm Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thiopurine S-methyltransferase YP_096830.1 3208538 R 272624 CDS YP_096831.1 52843032 3079750 complement(3209200..3211014) 1 NC_002942.5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 3211014 glmS 3079750 glmS Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glucosamine--fructose-6-phosphate aminotransferase YP_096831.1 3209200 R 272624 CDS YP_096832.1 52843033 3079568 complement(3211378..3212679) 1 NC_002942.5 phospholipase/lecithinase/hemolysin, lysophospholipase A, glycerophospholipid-cholesterol acyltransferase 3212679 3079568 lpg2837 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phospholipase/lecithinase/hemolysin, lysophospholipase A, glycerophospholipid-cholesterol acyltransferase YP_096832.1 3211378 R 272624 CDS YP_096833.1 52843034 3079754 3212932..3213696 1 NC_002942.5 rhodanese domain-containing protein 3213696 3079754 lpg2838 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 rhodanese domain-containing protein YP_096833.1 3212932 D 272624 CDS YP_096834.1 52843035 3079621 3213808..3214278 1 NC_002942.5 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3214278 smpB 3079621 smpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 SsrA-binding protein YP_096834.1 3213808 D 272624 CDS YP_096835.1 52843036 3079730 3214236..3214754 1 NC_002942.5 peroxiredoxin, AhpC/TSA family protein 3214754 3079730 lpg2840 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 peroxiredoxin, AhpC/TSA family protein YP_096835.1 3214236 D 272624 CDS YP_096836.1 52843037 3079733 3214880..3216079 1 NC_002942.5 major facilitator transporter 3216079 3079733 lpg2841 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major facilitator transporter YP_096836.1 3214880 D 272624 CDS YP_096837.1 52843038 3079910 3216234..3217640 1 NC_002942.5 PhoH protein (phosphate starvation inducible protein) 3217640 3079910 lpg2842 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 PhoH protein (phosphate starvation inducible protein) YP_096837.1 3216234 D 272624 CDS YP_096838.1 52843039 3079909 3217663..3218676 1 NC_002942.5 inosine 5'-monophosphate dehydrogenase 3218676 3079909 lpg2843 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inosine 5'-monophosphate dehydrogenase YP_096838.1 3217663 D 272624 CDS YP_096839.1 52843040 3079775 complement(3218707..3219792) 1 NC_002942.5 hypothetical protein 3219792 3079775 lpg2844 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096839.1 3218707 R 272624 CDS YP_096840.1 52843041 3079801 3220404..3221213 1 NC_002942.5 hypothetical protein 3221213 3079801 lpg2845 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096840.1 3220404 D 272624 CDS YP_096841.1 52843042 3079806 3221360..3221593 1 NC_002942.5 hypothetical protein 3221593 3079806 lpg2846 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096841.1 3221360 D 272624 CDS YP_096842.1 52843043 3079706 complement(3221661..3222623) 1 NC_002942.5 hypothetical protein 3222623 3079706 lpg2847 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096842.1 3221661 R 272624 CDS YP_096843.1 52843044 3079729 complement(3222761..3223774) 1 NC_002942.5 ribonuclease T2 family protein 3223774 3079729 lpg2848 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease T2 family protein YP_096843.1 3222761 R 272624 CDS YP_096844.1 52843045 3079707 3223904..3225208 1 NC_002942.5 hypothetical protein 3225208 3079707 lpg2849 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096844.1 3223904 D 272624 CDS YP_096845.1 52843046 3079834 complement(3225308..3225523) 1 NC_002942.5 cold shock transcriptional regulator CspA 3225523 3079834 lpg2850 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cold shock transcriptional regulator CspA YP_096845.1 3225308 R 272624 CDS YP_096846.1 52843047 3079787 complement(3225763..3227271) 1 NC_002942.5 protoporphyrinogen oxidase 3227271 hemG 3079787 hemG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 protoporphyrinogen oxidase YP_096846.1 3225763 R 272624 CDS YP_096847.1 52843048 3079785 complement(3227502..3228890) 1 NC_002942.5 amidase 3228890 amiC 3079785 amiC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amidase YP_096847.1 3227502 R 272624 CDS YP_096848.1 52843049 3079881 complement(3229121..3230779) 1 NC_002942.5 KQDN repeat-containing protein 3230779 3079881 lpg2853 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 KQDN repeat-containing protein YP_096848.1 3229121 R 272624 CDS YP_096849.1 52843050 3079580 complement(3230767..3231693) 1 NC_002942.5 hypothetical protein 3231693 3079580 lpg2854 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096849.1 3230767 R 272624 CDS YP_096850.1 52843051 3079794 complement(3231690..3232622) 1 NC_002942.5 hypothetical protein 3232622 3079794 lpg2855 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096850.1 3231690 R 272624 CDS YP_096851.1 52843052 3079646 complement(3232612..3233670) 1 NC_002942.5 hypothetical protein 3233670 3079646 lpg2856 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096851.1 3232612 R 272624 CDS YP_096852.1 52843053 3079723 complement(3234112..3235023) 1 NC_002942.5 hypothetical protein 3235023 3079723 lpg2858 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096852.1 3234112 R 272624 CDS YP_096853.1 52843054 3079769 complement(3235033..3236028) 1 NC_002942.5 MoxR 3236028 3079769 lpg2859 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 MoxR YP_096853.1 3235033 R 272624 CDS YP_096854.1 52843055 3079827 complement(3236205..3236681) 1 NC_002942.5 hypothetical protein 3236681 3079827 lpg2860 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096854.1 3236205 R 272624 CDS YP_096855.1 52843056 3079758 3236727..3237716 1 NC_002942.5 nitrogen regulation protein 3237716 3079758 lpg2861 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 nitrogen regulation protein YP_096855.1 3236727 D 272624 CDS YP_096856.1 52843057 3079883 complement(3237892..3239802) 1 NC_002942.5 coiled-coil containing protein 3239802 legC8 3079883 legC8 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 coiled-coil containing protein YP_096856.1 3237892 R 272624 CDS YP_096857.1 52843058 3079719 complement(3239928..3240707) 1 NC_002942.5 Involved in pteridine salvage and antifolate resistance; pteridine reductase 3240707 3079719 lpg2863 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 pteridine reductase YP_096857.1 3239928 R 272624 CDS YP_096858.1 52843059 3079761 3240854..3241972 1 NC_002942.5 hypothetical protein 3241972 3079761 lpg2864 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096858.1 3240854 D 272624 CDS YP_096859.1 52843060 3079858 3241975..3242469 1 NC_002942.5 6-pyruvoyl tetrahydrobiopterin synthase 3242469 3079858 lpg2865 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 6-pyruvoyl tetrahydrobiopterin synthase YP_096859.1 3241975 D 272624 CDS YP_096860.1 52843061 3079768 3242470..3244647 1 NC_002942.5 primosomal protein N' 3244647 3079768 lpg2866 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 primosomal protein N' YP_096860.1 3242470 D 272624 CDS YP_096861.1 52843062 3079663 3244644..3245036 1 NC_002942.5 hypothetical protein 3245036 3079663 lpg2867 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096861.1 3244644 D 272624 CDS YP_096862.1 52843063 3079766 complement(3245498..3246292) 1 NC_002942.5 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3246292 thyA 3079766 thyA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 thymidylate synthase YP_096862.1 3245498 R 272624 CDS YP_096863.1 52843064 3079700 complement(3246289..3247059) 1 NC_002942.5 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3247059 lgt 3079700 lgt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 prolipoprotein diacylglyceryl transferase YP_096863.1 3246289 R 272624 CDS YP_096864.1 52843065 3079865 complement(3247077..3247883) 1 NC_002942.5 hypothetical protein 3247883 3079865 lpg2870 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096864.1 3247077 R 272624 CDS YP_096865.1 52843066 3079830 complement(3247880..3250174) 1 NC_002942.5 phosphoenolpyruvate protein phosphotransferase PtsP 3250174 ptsP 3079830 ptsP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphoenolpyruvate protein phosphotransferase PtsP YP_096865.1 3247880 R 272624 CDS YP_096866.1 52843067 3079846 complement(3250175..3250702) 1 NC_002942.5 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3250702 3079846 lpg2872 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dinucleoside polyphosphate hydrolase YP_096866.1 3250175 R 272624 CDS YP_096867.1 52843068 3079746 3251055..3252065 1 NC_002942.5 L-asparaginase I 3252065 3079746 lpg2873 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 L-asparaginase I YP_096867.1 3251055 D 272624 CDS YP_096868.1 52843069 3079811 complement(3252163..3253047) 1 NC_002942.5 hypothetical protein 3253047 3079811 lpg2874 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096868.1 3252163 R 272624 CDS YP_096869.1 52843070 3079683 3253169..3254554 1 NC_002942.5 UDP-N-acetylglucosamine pyrophosphorylase 3254554 glmU 3079683 glmU Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylglucosamine pyrophosphorylase YP_096869.1 3253169 D 272624 CDS YP_096870.1 52843071 3079923 3254571..3255812 1 NC_002942.5 arsenite efflux protein ArsB 3255812 3079923 lpg2876 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 arsenite efflux protein ArsB YP_096870.1 3254571 D 272624 CDS YP_096871.1 52843072 3079654 complement(3255839..3257128) 1 NC_002942.5 hypothetical protein 3257128 3079654 lpg2877 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096871.1 3255839 R 272624 CDS YP_096872.1 52843073 3079575 3257398..3258462 1 NC_002942.5 cobalt/magnesium uptake transporter 3258462 corA 3079575 corA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cobalt/magnesium uptake transporter YP_096872.1 3257398 D 272624 CDS YP_096873.1 52843074 3079699 complement(3258575..3260326) 1 NC_002942.5 hypothetical protein 3260326 3079699 lpg2879 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096873.1 3258575 R 272624 CDS YP_096874.1 52843075 3079821 complement(3260567..3261202) 1 NC_002942.5 endonuclease III 3261202 nth 3079821 nth Legionella pneumophila subsp. pneumophila str. Philadelphia 1 endonuclease III YP_096874.1 3260567 R 272624 CDS YP_096875.1 52843076 3079817 complement(3261195..3261809) 1 NC_002942.5 iron-sulfur cluster binding protein 3261809 3079817 lpg2881 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 iron-sulfur cluster binding protein YP_096875.1 3261195 R 272624 CDS YP_096876.2 161723239 3079955 complement(3261809..3263821) 1 NC_002942.5 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 3263821 metG 3079955 metG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 methionyl-tRNA synthetase YP_096876.2 3261809 R 272624 CDS YP_096877.1 52843078 3079831 3264100..3264669 1 NC_002942.5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3264669 3079831 lpg2883 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_096877.1 3264100 D 272624 CDS YP_096878.1 52843079 3079698 complement(3264725..3265462) 1 NC_002942.5 hypothetical protein 3265462 3079698 lpg2884 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096878.1 3264725 R 272624 CDS YP_096879.1 52843080 3079710 complement(3265772..3266326) 1 NC_002942.5 hypothetical protein 3266326 3079710 lpg2885 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096879.1 3265772 R 272624 CDS YP_096880.1 52843081 3079930 complement(3266369..3267070) 1 NC_002942.5 exoenzyme S synthesis protein B 3267070 3079930 lpg2886 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 exoenzyme S synthesis protein B YP_096880.1 3266369 R 272624 CDS YP_096881.1 52843082 3079636 3267088..3268581 1 NC_002942.5 phosphomannose isomerase GDP mannose pyrophosphorylase 3268581 rfbA 3079636 rfbA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphomannose isomerase GDP mannose pyrophosphorylase YP_096881.1 3267088 D 272624 CDS YP_096882.1 52843083 3079631 3268809..3270722 1 NC_002942.5 hypothetical protein 3270722 3079631 lpg2888 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096882.1 3268809 D 272624 CDS YP_096883.1 52843084 3079833 3270853..3272727 1 NC_002942.5 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 3272727 gidA 3079833 gidA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_096883.1 3270853 D 272624 CDS YP_096884.1 52843085 3079738 3272724..3273350 1 NC_002942.5 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 3273350 gidB 3079738 gidB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 16S rRNA methyltransferase GidB YP_096884.1 3272724 D 272624 CDS YP_096885.1 52843086 3079943 3273353..3274123 1 NC_002942.5 conserved gene, chromosome partitioning protein ParA-like; sporulation initiation inhibitor protein Soj 3274123 soj 3079943 soj Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sporulation initiation inhibitor protein Soj YP_096885.1 3273353 D 272624 CDS YP_096886.1 52843087 3079774 3274137..3275006 1 NC_002942.5 chromosome partitioning protein ParB 3275006 3079774 lpg2892 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome partitioning protein ParB YP_096886.1 3274137 D 272624 CDS YP_096887.1 52843088 3079822 complement(3275035..3275577) 1 NC_002942.5 hypothetical protein 3275577 3079822 lpg2893 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096887.1 3275035 R 272624 CDS YP_096888.1 52843089 3079715 complement(3276056..3276925) 1 NC_002942.5 cytochrome c oxidase subunit III 3276925 3079715 lpg2894 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c oxidase subunit III YP_096888.1 3276056 R 272624 CDS YP_096889.1 52843090 3079740 complement(3277084..3277629) 1 NC_002942.5 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 3277629 coxG 3079740 coxG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome C oxidase assembly protein YP_096889.1 3277084 R 272624 CDS YP_096890.1 52843091 3079808 complement(3277639..3279255) 1 NC_002942.5 cytochrome c oxidase subunit I 3279255 3079808 lpg2896 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c oxidase subunit I YP_096890.1 3277639 R 272624 CDS YP_096891.1 52843092 3079704 complement(3279252..3280457) 1 NC_002942.5 cytochrome c oxidase subunit II 3280457 3079704 lpg2897 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c oxidase subunit II YP_096891.1 3279252 R 272624 CDS YP_096892.1 52843093 3079651 complement(3280539..3282152) 1 NC_002942.5 cytochrome c 3282152 3079651 lpg2898 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cytochrome c YP_096892.1 3280539 R 272624 CDS YP_096893.1 52843094 3079728 3282950..3283978 1 NC_002942.5 CapM protein, capsular polysaccharide biosynthesis 3283978 capM2 3079728 capM2 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CapM protein, capsular polysaccharide biosynthesis YP_096893.1 3282950 D 272624 CDS YP_096894.1 52843095 3079800 3284036..3284641 1 NC_002942.5 amino acid transporter LysE 3284641 3079800 lpg2901 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 amino acid transporter LysE YP_096894.1 3284036 D 272624 CDS YP_096895.1 52843096 3079893 3284867..3285292 1 NC_002942.5 hypothetical protein 3285292 3079893 lpg2902 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096895.1 3284867 D 272624 CDS YP_096896.1 52843097 3079789 3285417..3286169 1 NC_002942.5 ubiquinone/menaquinone biosynthesis methyltransferase UbiE 3286169 3079789 lpg2903 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinone/menaquinone biosynthesis methyltransferase UbiE YP_096896.1 3285417 D 272624 CDS YP_096897.1 52843098 3079906 3286171..3286794 1 NC_002942.5 hypothetical protein 3286794 3079906 lpg2904 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096897.1 3286171 D 272624 CDS YP_096898.1 52843099 3079845 3286884..3288533 1 NC_002942.5 ubiquinone biosynthesis AarF 3288533 3079845 lpg2905 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ubiquinone biosynthesis AarF YP_096898.1 3286884 D 272624 CDS YP_096899.1 52843100 3079942 3288717..3288986 1 NC_002942.5 sec-independent protein translocase TatB 3288986 tatB 3079942 tatB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sec-independent protein translocase TatB YP_096899.1 3288717 D 272624 CDS YP_096900.1 52843101 3079928 3289174..3290436 1 NC_002942.5 hypothetical protein 3290436 3079928 lpg2907 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096900.1 3289174 D 272624 CDS YP_096901.1 52843102 3079862 complement(3290460..3291329) 1 NC_002942.5 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein 3291329 msrA 3079862 msrA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 bifunctional methionine sulfoxide reductase B/A protein YP_096901.1 3290460 R 272624 CDS YP_096902.1 52843103 3079670 3291991..3292179 1 NC_002942.5 hypothetical protein 3292179 3079670 lpg2909 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096902.1 3291991 D 272624 CDS YP_096903.1 52843104 3079685 complement(3292396..3294330) 1 NC_002942.5 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 3294330 tynA 3079685 tynA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tyramine oxidase YP_096903.1 3292396 R 272624 CDS YP_096904.1 52843105 3079716 complement(3295187..3296458) 1 NC_002942.5 serine carboxypeptidase 3296458 3079716 lpg2911 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 serine carboxypeptidase YP_096904.1 3295187 R 272624 CDS YP_096905.1 52843106 3079844 3296964..3298451 1 NC_002942.5 hypothetical protein 3298451 3079844 lpg2912 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096905.1 3296964 D 272624 CDS YP_096906.1 52843107 3079840 complement(3298613..3300055) 1 NC_002942.5 hypothetical protein 3300055 3079840 lpg2913 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096906.1 3298613 R 272624 CDS YP_096907.1 52843108 3079897 complement(3300903..3301193) 1 NC_002942.5 hypothetical protein 3301193 3079897 lpg2914 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096907.1 3300903 R 272624 CDS YP_096908.1 52843109 3079570 complement(3301303..3301524) 1 NC_002942.5 hypothetical protein 3301524 3079570 lpg2915 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096908.1 3301303 R 272624 CDS YP_096909.1 52843110 3079848 complement(3301729..3302265) 1 NC_002942.5 hypothetical protein 3302265 3079848 lpg2916 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096909.1 3301729 R 272624 CDS YP_096910.1 52843111 3079642 complement(3302342..3303388) 1 NC_002942.5 hypothetical protein 3303388 3079642 lpg2917 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096910.1 3302342 R 272624 CDS YP_096911.1 52843112 3079890 complement(3303692..3304669) 1 NC_002942.5 lytic murein transglycosylase 3304669 3079890 lpg2918 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lytic murein transglycosylase YP_096911.1 3303692 R 272624 CDS YP_096912.1 52843113 3079655 3305184..3306362 1 NC_002942.5 (serine-type) D-alanyl-D-alanine carboxypeptidase 3306362 3079655 lpg2919 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (serine-type) D-alanyl-D-alanine carboxypeptidase YP_096912.1 3305184 D 272624 CDS YP_096913.1 52843114 3079747 3306596..3307015 1 NC_002942.5 hypothetical protein 3307015 3079747 lpg2920 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096913.1 3306596 D 272624 CDS YP_096914.1 52843115 3079744 3307008..3307334 1 NC_002942.5 hypothetical protein 3307334 3079744 lpg2921 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096914.1 3307008 D 272624 CDS YP_096915.1 52843116 3079871 complement(3307407..3308654) 1 NC_002942.5 ABC transporter permease 3308654 3079871 lpg2922 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter permease YP_096915.1 3307407 R 272624 CDS YP_096916.1 52843117 3079812 complement(3308597..3309298) 1 NC_002942.5 ABC transporter ATP-binding protein 3309298 3079812 lpg2923 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096916.1 3308597 R 272624 CDS YP_096917.1 52843118 3079763 complement(3309279..3310424) 1 NC_002942.5 lipoprotein 3310424 3079763 lpg2924 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein YP_096917.1 3309279 R 272624 CDS YP_096918.1 52843119 3079888 complement(3310421..3312049) 1 NC_002942.5 outer membrane efflux protein 3312049 3079888 lpg2925 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 outer membrane efflux protein YP_096918.1 3310421 R 272624 CDS YP_096919.1 52843120 3079641 complement(3312093..3312938) 1 NC_002942.5 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 3312938 apaH 3079641 apaH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 diadenosine tetraphosphatase YP_096919.1 3312093 R 272624 CDS YP_096920.1 52843121 3079749 complement(3312916..3314265) 1 NC_002942.5 hypothetical protein 3314265 3079749 lpg2927 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096920.1 3312916 R 272624 CDS YP_096921.1 52843122 3079898 complement(3314290..3315060) 1 NC_002942.5 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3315060 ksgA 3079898 ksgA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dimethyladenosine transferase YP_096921.1 3314290 R 272624 CDS YP_096922.1 52843123 3079748 3315396..3315797 1 NC_002942.5 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 3315797 panD 3079748 panD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 aspartate alpha-decarboxylase YP_096922.1 3315396 D 272624 CDS YP_096923.1 52843124 3079673 3315903..3316628 1 NC_002942.5 sec-independent protein translocase TatC 3316628 tatC 3079673 tatC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sec-independent protein translocase TatC YP_096923.1 3315903 D 272624 CDS YP_096924.1 52843125 3079823 3316678..3317001 1 NC_002942.5 hypothetical protein 3317001 3079823 lpg2931 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096924.1 3316678 D 272624 CDS YP_096925.1 52843126 3079675 complement(3317252..3317989) 1 NC_002942.5 CDP-6-deoxy-delta-3,4-glucoseen reductase 3317989 ubiB 3079675 ubiB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 CDP-6-deoxy-delta-3,4-glucoseen reductase YP_096925.1 3317252 R 272624 CDS YP_096926.1 52843127 3079814 complement(3317965..3319431) 1 NC_002942.5 oxidoreductase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3319431 yigC 3079814 yigC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 oxidoreductase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_096926.1 3317965 R 272624 CDS YP_096927.1 52843128 3079926 complement(3319576..3320847) 1 NC_002942.5 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3320847 rho 3079926 rho Legionella pneumophila subsp. pneumophila str. Philadelphia 1 transcription termination factor Rho YP_096927.1 3319576 R 272624 CDS YP_096928.1 52843129 3079686 complement(3321161..3321487) 1 NC_002942.5 hypothetical protein 3321487 trxA 3079686 trxA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096928.1 3321161 R 272624 CDS YP_096929.1 52843130 3079876 complement(3321700..3322434) 1 NC_002942.5 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3322434 3079876 lpg2936 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 16S ribosomal RNA methyltransferase RsmE YP_096929.1 3321700 R 272624 CDS YP_096930.1 52843131 3079915 3322598..3323992 1 NC_002942.5 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 3323992 fumC 3079915 fumC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 fumarate hydratase YP_096930.1 3322598 D 272624 CDS YP_096931.1 52843132 3079652 complement(3324084..3324707) 1 NC_002942.5 hypothetical protein 3324707 3079652 lpg2938 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096931.1 3324084 R 272624 CDS YP_096932.1 52843133 3079835 complement(3324704..3325876) 1 NC_002942.5 BNR/Asp box repeat-containing protein 3325876 3079835 lpg2939 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 BNR/Asp box repeat-containing protein YP_096932.1 3324704 R 272624 CDS YP_096933.1 52843134 3079965 complement(3325915..3326751) 1 NC_002942.5 conserved gene, may be fused with prior ORF; lipid A lauroyl acyltransferase 3326751 waaM 3079965 waaM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipid A lauroyl acyltransferase YP_096933.1 3325915 R 272624 CDS YP_096934.1 52843135 3080038 complement(3326744..3327592) 1 NC_002942.5 hypothetical protein 3327592 waaM 3080038 waaM Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096934.1 3326744 R 272624 CDS YP_096935.1 52843136 3079689 3327814..3328884 1 NC_002942.5 hypothetical protein 3328884 3079689 lpg2942 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096935.1 3327814 D 272624 CDS YP_096936.1 52843137 3079974 3329038..3329868 1 NC_002942.5 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 3329868 3079974 lpg2943 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-N-acetylglucosamine acyltransferase YP_096936.1 3329038 D 272624 CDS YP_096937.1 52843138 3079994 3329878..3330915 1 NC_002942.5 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 3330915 lpxD 3079994 lpxD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_096937.1 3329878 D 272624 CDS YP_096938.1 52843139 3079995 complement(3330887..3332044) 1 NC_002942.5 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 3332044 lpxB 3079995 lpxB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipid-A-disaccharide synthase YP_096938.1 3330887 R 272624 CDS YP_096939.1 52843140 3079737 complement(3332222..3333079) 1 NC_002942.5 hypothetical protein 3333079 3079737 lpg2946 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096939.1 3332222 R 272624 CDS YP_096940.1 52843141 3079860 complement(3333109..3334911) 1 NC_002942.5 ABC transporter ATP-binding protein 3334911 3079860 lpg2947 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ABC transporter ATP-binding protein YP_096940.1 3333109 R 272624 CDS YP_096941.1 52843142 3079649 complement(3335450..3335764) 1 NC_002942.5 hypothetical protein 3335764 3079649 lpg2948 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096941.1 3335450 R 272624 CDS YP_096942.1 52843143 3079851 complement(3335790..3337616) 1 NC_002942.5 asparagine synthetase B 3337616 wbmI 3079851 wbmI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 asparagine synthetase B YP_096942.1 3335790 R 272624 CDS YP_096943.1 52843144 3079908 complement(3337758..3338723) 1 NC_002942.5 hypothetical protein 3338723 3079908 lpg2950 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096943.1 3337758 R 272624 CDS YP_096944.1 52843145 3079916 3340034..3340984 1 NC_002942.5 cystathionine beta-lyase 3340984 3079916 lpg2951 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 cystathionine beta-lyase YP_096944.1 3340034 D 272624 CDS YP_096945.1 52843146 3079703 complement(3341079..3342122) 1 NC_002942.5 hypothetical protein 3342122 3079703 lpg2952 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096945.1 3341079 R 272624 CDS YP_096946.1 52843147 3079802 3342707..3343432 1 NC_002942.5 hypothetical protein 3343432 3079802 lpg2953 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096946.1 3342707 D 272624 CDS YP_096947.1 52843148 3079957 3343437..3344153 1 NC_002942.5 hypothetical protein 3344153 3079957 lpg2954 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096947.1 3343437 D 272624 CDS YP_096948.1 52843149 3079792 3344406..3344717 1 NC_002942.5 integration host factor beta subunit 3344717 hipB 3079792 hipB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 integration host factor beta subunit YP_096948.1 3344406 D 272624 CDS YP_096949.1 52843150 3079688 complement(3344733..3345299) 1 NC_002942.5 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 3345299 dcd 3079688 dcd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 deoxycytidine triphosphate deaminase YP_096949.1 3344733 R 272624 CDS YP_096950.1 52843151 3079662 complement(3345538..3346317) 1 NC_002942.5 stomatin like transmembrane protein 3346317 3079662 lpg2957 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 stomatin like transmembrane protein YP_096950.1 3345538 R 272624 CDS YP_096951.1 52843152 3079805 complement(3346336..3347841) 1 NC_002942.5 hypothetical protein 3347841 3079805 lpg2958 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096951.1 3346336 R 272624 CDS YP_096952.1 52843153 3079973 complement(3348048..3349640) 1 NC_002942.5 hypothetical protein 3349640 3079973 lpg2959 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096952.1 3348048 R 272624 CDS YP_096953.1 52843154 3079961 complement(3349937..3350908) 1 NC_002942.5 major outer membrane protein 3350908 3079961 lpg2960 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major outer membrane protein YP_096953.1 3349937 R 272624 CDS YP_096954.1 52843155 3079971 complement(3350981..3351847) 1 NC_002942.5 major outer membrane protein 3351847 3079971 lpg2961 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 major outer membrane protein YP_096954.1 3350981 R 272624 CDS YP_096955.1 52843156 3079970 complement(3352158..3353057) 1 NC_002942.5 hypothetical protein 3353057 3079970 lpg2962 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096955.1 3352158 R 272624 CDS YP_096956.1 52843157 3079739 3353070..3354149 1 NC_002942.5 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 3354149 pyrC 3079739 pyrC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 dihydroorotase YP_096956.1 3353070 D 272624 CDS YP_096957.1 52843158 3079978 3354133..3354756 1 NC_002942.5 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 3354756 rnt 3079978 rnt Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease T YP_096957.1 3354133 D 272624 CDS YP_096958.1 52843159 3079996 complement(3354883..3355488) 1 NC_002942.5 AhpC/Tsa family peroxynitrite reductase 3355488 3079996 lpg2965 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 AhpC/Tsa family peroxynitrite reductase YP_096958.1 3354883 R 272624 CDS YP_096959.1 52843160 3080034 complement(3355541..3355810) 1 NC_002942.5 glutaredoxin-like protein 3355810 3080034 lpg2966 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glutaredoxin-like protein YP_096959.1 3355541 R 272624 CDS YP_096960.1 52843161 3080041 3356177..3356767 1 NC_002942.5 superoxide dismutase 3356767 sodB 3080041 sodB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 superoxide dismutase YP_096960.1 3356177 D 272624 CDS YP_096961.1 52843162 3080057 3356827..3357996 1 NC_002942.5 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 3357996 argD 3080057 argD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 acetylornithine aminotransferase YP_096961.1 3356827 D 272624 CDS YP_096962.1 52843163 3079983 complement(3358125..3358910) 1 NC_002942.5 hypothetical protein 3358910 3079983 lpg2969 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096962.1 3358125 R 272624 CDS YP_096963.1 52843164 3080006 complement(3359048..3359836) 1 NC_002942.5 glycerophosphoryl diester phosphodiesterase 3359836 3080006 lpg2970 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 glycerophosphoryl diester phosphodiesterase YP_096963.1 3359048 R 272624 CDS YP_096964.1 52843165 3079850 3360082..3361752 1 NC_002942.5 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 3361752 maeA 3079850 maeA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 malate dehydrogenase YP_096964.1 3360082 D 272624 CDS YP_096965.1 52843166 3080016 3361982..3362950 1 NC_002942.5 Sua5/YciO/YrdC/YwlC family protein 3362950 3080016 lpg2972 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Sua5/YciO/YrdC/YwlC family protein YP_096965.1 3361982 D 272624 CDS YP_096966.1 52843167 3080021 complement(3363124..3363975) 1 NC_002942.5 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 3363975 psd 3080021 psd Legionella pneumophila subsp. pneumophila str. Philadelphia 1 phosphatidylserine decarboxylase YP_096966.1 3363124 R 272624 CDS YP_096967.1 52843168 3079990 complement(3364068..3366683) 1 NC_002942.5 hypothetical protein 3366683 3079990 lpg2975 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096967.1 3364068 R 272624 CDS YP_096968.1 52843169 3079992 complement(3366946..3368475) 1 NC_002942.5 hypothetical protein 3368475 3079992 lpg2976 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096968.1 3366946 R 272624 CDS YP_096969.1 52843170 3080035 complement(3369048..3370397) 1 NC_002942.5 zinc metalloprotease 3370397 3080035 lpg2977 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 zinc metalloprotease YP_096969.1 3369048 R 272624 CDS YP_096970.1 52843171 3079991 complement(3370378..3370737) 1 NC_002942.5 hypothetical protein 3370737 3079991 lpg2978 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096970.1 3370378 R 272624 CDS YP_096971.1 52843172 3080029 3370964..3371818 1 NC_002942.5 hypothetical protein 3371818 3080029 lpg2979 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096971.1 3370964 D 272624 CDS YP_096972.1 52843173 3079976 complement(3371925..3374180) 1 NC_002942.5 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3374180 parC 3079976 parC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 DNA topoisomerase IV subunit A YP_096972.1 3371925 R 272624 CDS YP_096973.1 52843174 3080046 complement(3374808..3375230) 1 NC_002942.5 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 3375230 atpC 3080046 atpC Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit epsilon YP_096973.1 3374808 R 272624 CDS YP_096974.1 52843175 3079894 complement(3375242..3376618) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 3376618 atpD 3079894 atpD Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit beta YP_096974.1 3375242 R 272624 CDS YP_096975.1 52843176 3080028 complement(3376631..3377497) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 3377497 atpG 3080028 atpG Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit gamma YP_096975.1 3376631 R 272624 CDS YP_096976.1 52843177 3080013 complement(3377587..3379140) 1 NC_002942.5 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 3379140 3080013 lpg2984 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit alpha YP_096976.1 3377587 R 272624 CDS YP_096977.1 52843178 3080009 complement(3379158..3379715) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 3379715 atpH 3080009 atpH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit delta YP_096977.1 3379158 R 272624 CDS YP_096978.1 52843179 3079752 complement(3379702..3380172) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 3380172 atpF 3079752 atpF Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit B YP_096978.1 3379702 R 272624 CDS YP_096979.1 52843180 3079993 complement(3380224..3380499) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 3380499 atpE 3079993 atpE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit C YP_096979.1 3380224 R 272624 CDS YP_096980.1 52843181 3080018 complement(3380540..3381418) 1 NC_002942.5 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 3381418 atpB 3080018 atpB Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase F0F1 subunit A YP_096980.1 3380540 R 272624 CDS YP_096981.1 52843182 3080048 complement(3381369..3381764) 1 NC_002942.5 ATP synthase I 3381764 atpI 3080048 atpI Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ATP synthase I YP_096981.1 3381369 R 272624 CDS YP_096982.1 52843183 3080052 complement(3381904..3382047) 1 NC_002942.5 hypothetical protein 3382047 3080052 lpg2990 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096982.1 3381904 R 272624 CDS YP_096983.1 52843184 3080037 complement(3382233..3382820) 1 NC_002942.5 hemolysin, lipoprotein 3382820 3080037 lpg2991 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hemolysin, lipoprotein YP_096983.1 3382233 R 272624 CDS YP_096984.1 52843185 3079999 complement(3382822..3383394) 1 NC_002942.5 hypothetical protein 3383394 3079999 lpg2992 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096984.1 3382822 R 272624 CDS YP_096985.1 52843186 3079885 complement(3383398..3383997) 1 NC_002942.5 hypothetical protein 3383997 gmhA 3079885 gmhA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096985.1 3383398 R 272624 CDS YP_096986.1 52843187 3080025 complement(3384024..3384380) 1 NC_002942.5 hypothetical protein 3384380 3080025 lpg2994 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096986.1 3384024 R 272624 CDS YP_096987.1 52843188 3079751 complement(3384402..3386213) 1 NC_002942.5 lipoprotein 3386213 3079751 lpg2995 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 lipoprotein YP_096987.1 3384402 R 272624 CDS YP_096988.1 52843189 3080059 3386253..3387104 1 NC_002942.5 tetrapyrrole (corrin/porphyrin) methylase 3387104 3080059 lpg2996 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tetrapyrrole (corrin/porphyrin) methylase YP_096988.1 3386253 D 272624 CDS YP_096989.1 52843190 3080051 3387135..3388301 1 NC_002942.5 alkane-1 monooxygenase 3388301 3080051 lpg2997 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 alkane-1 monooxygenase YP_096989.1 3387135 D 272624 CDS YP_096990.1 52843191 3079980 complement(3388349..3390526) 1 NC_002942.5 sulfate transporter 3390526 3079980 lpg2998 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 sulfate transporter YP_096990.1 3388349 R 272624 CDS YP_096991.1 52843192 3080045 3391003..3391803 1 NC_002942.5 hypothetical protein 3391803 legP 3080045 legP Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096991.1 3391003 D 272624 CDS YP_096992.1 52843193 3080022 complement(3391800..3393638) 1 NC_002942.5 hypothetical protein 3393638 3080022 lpg3000 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096992.1 3391800 R 272624 CDS YP_096993.1 52843194 3080058 complement(3393934..3395274) 1 NC_002942.5 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3395274 trmE 3080058 trmE Legionella pneumophila subsp. pneumophila str. Philadelphia 1 tRNA modification GTPase TrmE YP_096993.1 3393934 R 272624 CDS YP_096994.1 52843195 3079986 complement(3395275..3396945) 1 NC_002942.5 inner membrane protein, 60 kDa 3396945 3079986 lpg3002 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 inner membrane protein, 60 kDa YP_096994.1 3395275 R 272624 CDS YP_096995.1 52843196 3080033 complement(3396955..3397200) 1 NC_002942.5 hypothetical protein 3397200 3080033 lpg3003 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 hypothetical protein YP_096995.1 3396955 R 272624 CDS YP_096996.1 52843197 3079984 complement(3397167..3397355) 1 NC_002942.5 ribonuclease P protein component 3397355 rnpA 3079984 rnpA Legionella pneumophila subsp. pneumophila str. Philadelphia 1 ribonuclease P protein component YP_096996.1 3397167 R 272624 CDS YP_096997.1 52843198 3080000 complement(3397512..3397646) 1 NC_002942.5 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3397646 rpmH 3080000 rpmH Legionella pneumophila subsp. pneumophila str. Philadelphia 1 50S ribosomal protein L34 YP_096997.1 3397512 R 272624 CDS