-- dump date   	20140619_132127
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1126011000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1126011000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1126011000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011000004	Walker A motif; other site
1126011000005	ATP binding site [chemical binding]; other site
1126011000006	Walker B motif; other site
1126011000007	arginine finger; other site
1126011000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1126011000009	DnaA box-binding interface [nucleotide binding]; other site
1126011000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
1126011000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1126011000012	putative DNA binding surface [nucleotide binding]; other site
1126011000013	dimer interface [polypeptide binding]; other site
1126011000014	beta-clamp/clamp loader binding surface; other site
1126011000015	beta-clamp/translesion DNA polymerase binding surface; other site
1126011000016	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1126011000017	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1126011000018	S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988
1126011000019	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
1126011000020	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1126011000021	Walker A/P-loop; other site
1126011000022	ATP binding site [chemical binding]; other site
1126011000023	Q-loop/lid; other site
1126011000024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011000025	ABC transporter signature motif; other site
1126011000026	Walker B; other site
1126011000027	D-loop; other site
1126011000028	H-loop/switch region; other site
1126011000029	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1126011000030	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011000031	Mg2+ binding site [ion binding]; other site
1126011000032	G-X-G motif; other site
1126011000033	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1126011000034	anchoring element; other site
1126011000035	dimer interface [polypeptide binding]; other site
1126011000036	ATP binding site [chemical binding]; other site
1126011000037	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1126011000038	active site
1126011000039	putative metal-binding site [ion binding]; other site
1126011000040	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1126011000041	DNA gyrase subunit A; Validated; Region: PRK05560
1126011000042	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1126011000043	CAP-like domain; other site
1126011000044	active site
1126011000045	primary dimer interface [polypeptide binding]; other site
1126011000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011000051	cardiolipin synthetase; Reviewed; Region: PRK12452
1126011000052	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1126011000053	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1126011000054	putative active site [active]
1126011000055	catalytic site [active]
1126011000056	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1126011000057	putative active site [active]
1126011000058	catalytic site [active]
1126011000059	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1126011000060	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011000061	Coenzyme A binding pocket [chemical binding]; other site
1126011000062	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
1126011000063	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1126011000064	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1126011000065	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
1126011000066	diphosphomevalonate decarboxylase; Region: PLN02407
1126011000067	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
1126011000068	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1126011000069	potential frameshift: common BLAST hit: gi|116872472|ref|YP_849253.1| N-acetylmuramoyl-L-alanine amidase
1126011000070	cytochrome aa3 quinol oxidase, subunit II; Region: QOXA; TIGR01432
1126011000071	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1126011000072	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1126011000073	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1126011000074	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1126011000075	D-pathway; other site
1126011000076	Putative ubiquinol binding site [chemical binding]; other site
1126011000077	Low-spin heme (heme b) binding site [chemical binding]; other site
1126011000078	Putative water exit pathway; other site
1126011000079	Binuclear center (heme o3/CuB) [ion binding]; other site
1126011000080	K-pathway; other site
1126011000081	Putative proton exit pathway; other site
1126011000082	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1126011000083	Subunit I/III interface [polypeptide binding]; other site
1126011000084	Subunit III/IV interface [polypeptide binding]; other site
1126011000085	cytochrome aa3 quinol oxidase, subunit IV; Region: QoxD; TIGR02901
1126011000086	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1126011000087	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1126011000088	putative active site [active]
1126011000089	putative metal binding site [ion binding]; other site
1126011000090	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1126011000091	beta-galactosidase; Region: BGL; TIGR03356
1126011000092	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
1126011000093	Bacterial SH3 domain; Region: SH3_3; pfam08239
1126011000094	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
1126011000095	putative active site [active]
1126011000096	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011000097	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011000098	DNA-binding site [nucleotide binding]; DNA binding site
1126011000099	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1126011000100	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011000101	active site
1126011000102	active pocket/dimerization site; other site
1126011000103	phosphorylation site [posttranslational modification]
1126011000104	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1126011000105	active site
1126011000106	phosphorylation site [posttranslational modification]
1126011000107	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1126011000108	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1126011000109	hypothetical protein; Provisional; Region: PRK02947
1126011000110	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011000111	putative active site [active]
1126011000112	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1126011000113	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1126011000114	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1126011000115	active site turn [active]
1126011000116	phosphorylation site [posttranslational modification]
1126011000117	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1126011000118	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1126011000119	HPr interaction site; other site
1126011000120	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1126011000121	active site
1126011000122	phosphorylation site [posttranslational modification]
1126011000123	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1126011000124	putative dimer interface [polypeptide binding]; other site
1126011000125	catalytic triad [active]
1126011000126	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011000127	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
1126011000128	Walker A/P-loop; other site
1126011000129	ATP binding site [chemical binding]; other site
1126011000130	Q-loop/lid; other site
1126011000131	ABC transporter signature motif; other site
1126011000132	Walker B; other site
1126011000133	D-loop; other site
1126011000134	H-loop/switch region; other site
1126011000135	Protein of unknown function (DUF2705); Region: DUF2705; pfam10920
1126011000136	Protein of unknown function (DUF2712); Region: DUF2712; pfam10916
1126011000137	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011000138	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000139	active site
1126011000140	motif I; other site
1126011000141	motif II; other site
1126011000142	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000143	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011000144	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011000145	DNA binding site [nucleotide binding]
1126011000146	domain linker motif; other site
1126011000147	Ligand-binding domain of DNA-binding regulatory protein from Corynebacterium glutamicum which has a unique ability to produce significant amounts of L-glutamate directly from cheap sugar and ammonia; Region: PBP1_LacI_like_13; cd06299
1126011000148	dimerization interface [polypeptide binding]; other site
1126011000149	putative ligand binding site [chemical binding]; other site
1126011000150	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011000151	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011000152	nucleotide binding site [chemical binding]; other site
1126011000153	Butyrate kinase [Energy production and conversion]; Region: COG3426
1126011000154	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
1126011000155	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
1126011000156	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011000157	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011000158	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1126011000159	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1126011000160	dimer interface [polypeptide binding]; other site
1126011000161	active site
1126011000162	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1126011000163	dimer interface [polypeptide binding]; other site
1126011000164	active site
1126011000165	putrescine carbamoyltransferase; Provisional; Region: PRK02255
1126011000166	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1126011000167	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1126011000168	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1126011000169	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1126011000170	agmatine deiminase; Provisional; Region: PRK13551
1126011000171	agmatine deiminase; Region: agmatine_aguA; TIGR03380
1126011000172	carbamate kinase; Reviewed; Region: PRK12686
1126011000173	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1126011000174	putative substrate binding site [chemical binding]; other site
1126011000175	nucleotide binding site [chemical binding]; other site
1126011000176	nucleotide binding site [chemical binding]; other site
1126011000177	homodimer interface [polypeptide binding]; other site
1126011000178	agmatine deiminase; Provisional; Region: PRK13551
1126011000179	agmatine deiminase; Region: agmatine_aguA; TIGR03380
1126011000180	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011000181	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011000182	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011000183	putative active site [active]
1126011000184	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1126011000185	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1126011000186	arginine deiminase; Provisional; Region: PRK01388
1126011000187	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1126011000188	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1126011000189	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1126011000190	dimer interface [polypeptide binding]; other site
1126011000191	ssDNA binding site [nucleotide binding]; other site
1126011000192	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011000193	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1126011000194	Predicted membrane protein [Function unknown]; Region: COG3212
1126011000195	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1126011000196	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1126011000197	putative accessory gene regulator protein; Provisional; Region: PRK01100
1126011000198	Staphylococcal AgrD protein; Region: AgrD; cl05477
1126011000199	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1126011000200	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011000201	ATP binding site [chemical binding]; other site
1126011000202	Mg2+ binding site [ion binding]; other site
1126011000203	G-X-G motif; other site
1126011000204	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1126011000205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011000206	active site
1126011000207	phosphorylation site [posttranslational modification]
1126011000208	intermolecular recognition site; other site
1126011000209	LytTr DNA-binding domain; Region: LytTR; pfam04397
1126011000210	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
1126011000211	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1126011000212	DHH family; Region: DHH; pfam01368
1126011000213	DHHA1 domain; Region: DHHA1; pfam02272
1126011000214	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1126011000215	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1126011000216	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1126011000217	replicative DNA helicase; Provisional; Region: PRK05748
1126011000218	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1126011000219	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1126011000220	Walker A motif; other site
1126011000221	ATP binding site [chemical binding]; other site
1126011000222	Walker B motif; other site
1126011000223	DNA binding loops [nucleotide binding]
1126011000224	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1126011000225	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1126011000226	GDP-binding site [chemical binding]; other site
1126011000227	ACT binding site; other site
1126011000228	IMP binding site; other site
1126011000229	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842
1126011000230	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1126011000231	type VII secretion protein EsaA, N-terminal domain; Region: T7_esaA_Nterm; TIGR03929
1126011000232	Predicted membrane protein [Function unknown]; Region: COG1511
1126011000233	Predicted membrane protein (DUF2085); Region: DUF2085; pfam09858
1126011000234	WXG100 protein secretion system (Wss), protein EssA; Region: EssA; cl11266
1126011000235	Uncharacterized small protein [Function unknown]; Region: COG5417
1126011000236	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; cl01868
1126011000237	type VII secretion protein EssB; Region: T7_EssB; TIGR03926
1126011000238	potential frameshift: common BLAST hit: gi|46906294|ref|YP_012683.1| diarrheal toxin/FtsK/SpoIIIE family protein
1126011000239	potential frameshift: common BLAST hit: gi|46906294|ref|YP_012683.1| diarrheal toxin/FtsK/SpoIIIE family protein
1126011000240	potential frameshift: common BLAST hit: gi|46906294|ref|YP_012683.1| diarrheal toxin/FtsK/SpoIIIE family protein
1126011000241	potential frameshift: common BLAST hit: gi|226222716|ref|YP_002756823.1| carboxyphosphonoenolpyruvate phosphonomutase
1126011000242	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1126011000243	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1126011000244	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1126011000245	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1126011000246	DNA binding site [nucleotide binding]
1126011000247	active site
1126011000248	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1126011000249	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1126011000250	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1126011000251	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1126011000252	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178
1126011000253	putative ligand binding site [chemical binding]; other site
1126011000254	putative NAD binding site [chemical binding]; other site
1126011000255	catalytic site [active]
1126011000256	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011000257	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011000258	DNA binding residues [nucleotide binding]
1126011000259	putative dimer interface [polypeptide binding]; other site
1126011000260	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011000261	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011000262	active site
1126011000263	catalytic tetrad [active]
1126011000264	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000265	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011000266	ATP synthase subunit C; Region: ATP-synt_C; cl00466
1126011000267	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1126011000268	F0F1 ATP synthase subunit alpha; Provisional; Region: PRK13343
1126011000269	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1126011000270	Walker A motif; other site
1126011000271	ATP binding site [chemical binding]; other site
1126011000272	Walker B motif; other site
1126011000273	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1126011000274	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1126011000275	core domain interface [polypeptide binding]; other site
1126011000276	delta subunit interface [polypeptide binding]; other site
1126011000277	epsilon subunit interface [polypeptide binding]; other site
1126011000278	F0F1 ATP synthase subunit beta; Provisional; Region: PRK12597
1126011000279	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1126011000280	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1126011000281	alpha subunit interaction interface [polypeptide binding]; other site
1126011000282	Walker A motif; other site
1126011000283	ATP binding site [chemical binding]; other site
1126011000284	Walker B motif; other site
1126011000285	inhibitor binding site; inhibition site
1126011000286	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1126011000287	ATP synthase, Delta/Epsilon chain, beta-sandwich domain; Region: ATP-synt_DE_N; pfam02823
1126011000288	gamma subunit interface [polypeptide binding]; other site
1126011000289	epsilon subunit interface [polypeptide binding]; other site
1126011000290	LBP interface [polypeptide binding]; other site
1126011000291	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000292	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1126011000293	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011000294	active pocket/dimerization site; other site
1126011000295	active site
1126011000296	phosphorylation site [posttranslational modification]
1126011000297	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1126011000298	active site
1126011000299	phosphorylation site [posttranslational modification]
1126011000300	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1126011000301	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1126011000302	Domain of unknown function (DUF956); Region: DUF956; pfam06115
1126011000303	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
1126011000304	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1126011000305	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1126011000306	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011000307	dimerization interface [polypeptide binding]; other site
1126011000308	putative DNA binding site [nucleotide binding]; other site
1126011000309	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1126011000310	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1126011000311	dimer interface [polypeptide binding]; other site
1126011000312	FMN binding site [chemical binding]; other site
1126011000313	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1126011000314	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1126011000315	active site
1126011000316	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1126011000317	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1126011000318	Interdomain contacts; other site
1126011000319	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1126011000320	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1126011000321	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011000322	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011000323	nucleotide binding site [chemical binding]; other site
1126011000324	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011000325	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011000326	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1126011000327	Walker A/P-loop; other site
1126011000328	ATP binding site [chemical binding]; other site
1126011000329	Q-loop/lid; other site
1126011000330	ABC transporter signature motif; other site
1126011000331	Walker B; other site
1126011000332	D-loop; other site
1126011000333	H-loop/switch region; other site
1126011000334	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011000335	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011000336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011000337	Walker A/P-loop; other site
1126011000338	ATP binding site [chemical binding]; other site
1126011000339	Q-loop/lid; other site
1126011000340	ABC transporter signature motif; other site
1126011000341	Walker B; other site
1126011000342	D-loop; other site
1126011000343	H-loop/switch region; other site
1126011000344	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1126011000345	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011000346	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011000347	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011000348	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1126011000349	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1126011000350	substrate binding pocket [chemical binding]; other site
1126011000351	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1126011000352	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000353	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1126011000354	ligand binding site [chemical binding]; other site
1126011000355	flexible hinge region; other site
1126011000356	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1126011000357	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011000358	non-specific DNA binding site [nucleotide binding]; other site
1126011000359	salt bridge; other site
1126011000360	sequence-specific DNA binding site [nucleotide binding]; other site
1126011000361	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
1126011000362	Predicted secreted protein [Function unknown]; Region: COG5437
1126011000363	Phage-related protein [Function unknown]; Region: COG5412
1126011000364	Phage tail protein; Region: Sipho_tail; pfam05709
1126011000365	potential frameshift: common BLAST hit: gi|46906363|ref|YP_012752.1| minor structural protein
1126011000366	Phage-related holin (Lysis protein) [General function prediction only]; Region: COG4824
1126011000367	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1126011000368	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1126011000369	active site
1126011000370	metal binding site [ion binding]; metal-binding site
1126011000371	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1126011000372	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
1126011000373	putative active site [active]
1126011000374	putative metal binding site [ion binding]; other site
1126011000375	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1126011000376	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1126011000377	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
1126011000378	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1126011000379	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
1126011000380	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1126011000381	active site
1126011000382	Uncharacterized conserved protein [Function unknown]; Region: COG3592
1126011000383	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011000384	Coenzyme A binding pocket [chemical binding]; other site
1126011000385	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1126011000386	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1126011000387	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1126011000388	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000389	dimer interface [polypeptide binding]; other site
1126011000390	conserved gate region; other site
1126011000391	putative PBP binding loops; other site
1126011000392	ABC-ATPase subunit interface; other site
1126011000393	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1126011000394	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1126011000395	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000396	dimer interface [polypeptide binding]; other site
1126011000397	conserved gate region; other site
1126011000398	putative PBP binding loops; other site
1126011000399	ABC-ATPase subunit interface; other site
1126011000400	Protein of unknown function (DUF3130; Region: DUF3130; cl12867
1126011000401	LXG domain of WXG superfamily; Region: LXG; pfam04740
1126011000402	ADP-ribosyl cyclase, also known as cyclic ADP-ribose hydrolase or CD38; Region: Rib_hydrolase; cl08346
1126011000403	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1126011000404	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1126011000405	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1126011000406	peptide binding site [polypeptide binding]; other site
1126011000407	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1126011000408	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
1126011000409	metal binding site [ion binding]; metal-binding site
1126011000410	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
1126011000411	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1126011000412	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1126011000413	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011000414	ABC-ATPase subunit  interface; other site
1126011000415	dimer interface [polypeptide binding]; other site
1126011000416	putative PBP binding regions; other site
1126011000417	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1126011000418	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000419	ligand binding site [chemical binding]; other site
1126011000420	flexible hinge region; other site
1126011000421	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1126011000422	DEAD_2; Region: DEAD_2; pfam06733
1126011000423	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1126011000424	sugar phosphate phosphatase; Provisional; Region: PRK10513
1126011000425	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000426	active site
1126011000427	motif I; other site
1126011000428	motif II; other site
1126011000429	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000430	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1126011000431	Collagen binding domain; Region: Collagen_bind; pfam05737
1126011000432	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011000433	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011000434	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011000435	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1126011000436	Collagen binding domain; Region: Collagen_bind; pfam05737
1126011000437	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011000438	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011000439	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011000440	DNA polymerase III subunit delta'; Validated; Region: PRK08058
1126011000441	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1126011000442	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1126011000443	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467
1126011000444	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1126011000445	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011000446	S-adenosylmethionine binding site [chemical binding]; other site
1126011000447	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1126011000448	GIY-YIG motif/motif A; other site
1126011000449	putative active site [active]
1126011000450	putative metal binding site [ion binding]; other site
1126011000451	Predicted methyltransferases [General function prediction only]; Region: COG0313
1126011000452	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1126011000453	putative SAM binding site [chemical binding]; other site
1126011000454	putative homodimer interface [polypeptide binding]; other site
1126011000455	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1126011000456	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1126011000457	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1126011000458	Uncharacterized conserved protein [Function unknown]; Region: COG5361
1126011000459	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
1126011000460	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
1126011000461	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011000462	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1126011000463	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1126011000464	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1126011000465	active site
1126011000466	HIGH motif; other site
1126011000467	KMSKS motif; other site
1126011000468	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1126011000469	tRNA binding surface [nucleotide binding]; other site
1126011000470	anticodon binding site; other site
1126011000471	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1126011000472	dimer interface [polypeptide binding]; other site
1126011000473	putative tRNA-binding site [nucleotide binding]; other site
1126011000474	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1126011000475	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011000476	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011000477	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1126011000478	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1126011000479	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000480	dimer interface [polypeptide binding]; other site
1126011000481	conserved gate region; other site
1126011000482	putative PBP binding loops; other site
1126011000483	ABC-ATPase subunit interface; other site
1126011000484	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011000485	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000486	dimer interface [polypeptide binding]; other site
1126011000487	conserved gate region; other site
1126011000488	putative PBP binding loops; other site
1126011000489	ABC-ATPase subunit interface; other site
1126011000490	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1126011000491	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011000492	alpha-glucosidase; Provisional; Region: PRK10426
1126011000493	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1126011000494	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
1126011000495	active site
1126011000496	catalytic site [active]
1126011000497	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1126011000498	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1126011000499	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
1126011000500	trimer interface [polypeptide binding]; other site
1126011000501	active site
1126011000502	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
1126011000503	catalytic site [active]
1126011000504	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1126011000505	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1126011000506	Ca binding site [ion binding]; other site
1126011000507	active site
1126011000508	catalytic site [active]
1126011000509	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1126011000510	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1126011000511	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1126011000512	active site
1126011000513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3583
1126011000514	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1126011000515	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1126011000516	G5 domain; Region: G5; pfam07501
1126011000517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1126011000518	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1126011000519	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1126011000520	putative active site [active]
1126011000521	putative metal binding site [ion binding]; other site
1126011000522	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1126011000523	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1126011000524	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011000525	S-adenosylmethionine binding site [chemical binding]; other site
1126011000526	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1126011000527	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1126011000528	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1126011000529	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1126011000530	putative active site [active]
1126011000531	YdjC motif; other site
1126011000532	Mg binding site [ion binding]; other site
1126011000533	putative homodimer interface [polypeptide binding]; other site
1126011000534	pur operon repressor; Provisional; Region: PRK09213
1126011000535	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1126011000536	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011000537	active site
1126011000538	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1126011000539	HlyD family secretion protein; Region: HlyD_3; pfam13437
1126011000540	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011000541	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011000542	Walker A/P-loop; other site
1126011000543	ATP binding site [chemical binding]; other site
1126011000544	Q-loop/lid; other site
1126011000545	ABC transporter signature motif; other site
1126011000546	Walker B; other site
1126011000547	D-loop; other site
1126011000548	H-loop/switch region; other site
1126011000549	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011000550	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1126011000551	FtsX-like permease family; Region: FtsX; pfam02687
1126011000552	regulatory protein SpoVG; Reviewed; Region: PRK13259
1126011000553	regulatory protein SpoVG; Reviewed; Region: PRK13259
1126011000554	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1126011000555	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1126011000556	Substrate binding site; other site
1126011000557	Mg++ binding site; other site
1126011000558	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1126011000559	active site
1126011000560	substrate binding site [chemical binding]; other site
1126011000561	CoA binding site [chemical binding]; other site
1126011000562	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1126011000563	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1126011000564	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011000565	active site
1126011000566	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000567	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011000568	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011000569	Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C; Region: PI-PLCc; cd00137
1126011000570	active site
1126011000571	catalytic site [active]
1126011000572	Thiol-activated cytolysin; Region: Thiol_cytolysin; pfam01289
1126011000573	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1126011000574	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1126011000575	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1126011000576	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1126011000577	active site
1126011000578	Zn binding site [ion binding]; other site
1126011000579	ActA Protein; Region: ActA; pfam05058
1126011000580	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
1126011000581	Zn binding site [ion binding]; other site
1126011000582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1126011000583	hypothetical protein; Provisional; Region: PRK01119
1126011000584	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1126011000585	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1126011000586	active site
1126011000587	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1126011000588	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1126011000589	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011000590	NAD binding site [chemical binding]; other site
1126011000591	dimer interface [polypeptide binding]; other site
1126011000592	substrate binding site [chemical binding]; other site
1126011000593	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1126011000594	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1126011000595	5S rRNA interface [nucleotide binding]; other site
1126011000596	CTC domain interface [polypeptide binding]; other site
1126011000597	L16 interface [polypeptide binding]; other site
1126011000598	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011000599	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011000600	Coenzyme A binding pocket [chemical binding]; other site
1126011000601	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1126011000602	putative active site [active]
1126011000603	catalytic residue [active]
1126011000604	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1126011000605	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1126011000606	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011000607	ATP binding site [chemical binding]; other site
1126011000608	putative Mg++ binding site [ion binding]; other site
1126011000609	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011000610	nucleotide binding region [chemical binding]; other site
1126011000611	ATP-binding site [chemical binding]; other site
1126011000612	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1126011000613	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1126011000614	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1126011000615	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011000616	RNA binding surface [nucleotide binding]; other site
1126011000617	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1126011000618	Septum formation initiator; Region: DivIC; pfam04977
1126011000619	hypothetical protein; Provisional; Region: PRK08582
1126011000620	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1126011000621	RNA binding site [nucleotide binding]; other site
1126011000622	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1126011000623	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011000624	active site
1126011000625	FtsH Extracellular; Region: FtsH_ext; pfam06480
1126011000626	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1126011000627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011000628	Walker A motif; other site
1126011000629	ATP binding site [chemical binding]; other site
1126011000630	Walker B motif; other site
1126011000631	arginine finger; other site
1126011000632	Peptidase family M41; Region: Peptidase_M41; pfam01434
1126011000633	pantothenate kinase; Reviewed; Region: PRK13318
1126011000634	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1126011000635	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1126011000636	dimerization interface [polypeptide binding]; other site
1126011000637	domain crossover interface; other site
1126011000638	redox-dependent activation switch; other site
1126011000639	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1126011000640	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1126011000641	dimer interface [polypeptide binding]; other site
1126011000642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011000643	catalytic residue [active]
1126011000644	dihydropteroate synthase; Region: DHPS; TIGR01496
1126011000645	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1126011000646	substrate binding pocket [chemical binding]; other site
1126011000647	dimer interface [polypeptide binding]; other site
1126011000648	inhibitor binding site; inhibition site
1126011000649	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1126011000650	homooctamer interface [polypeptide binding]; other site
1126011000651	active site
1126011000652	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1126011000653	catalytic center binding site [active]
1126011000654	ATP binding site [chemical binding]; other site
1126011000655	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1126011000656	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1126011000657	FMN binding site [chemical binding]; other site
1126011000658	active site
1126011000659	catalytic residues [active]
1126011000660	substrate binding site [chemical binding]; other site
1126011000661	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1126011000662	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1126011000663	dimer interface [polypeptide binding]; other site
1126011000664	putative anticodon binding site; other site
1126011000665	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1126011000666	motif 1; other site
1126011000667	active site
1126011000668	motif 2; other site
1126011000669	motif 3; other site
1126011000670	potential protein location (hypothetical protein MUO_01290 [Listeria monocytogenes 07PF0776]) that overlaps RNA (tRNA-K)
1126011000671	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
1126011000672	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1126011000673	Arginine kinase [Amino acid transport and metabolism]; Region: COG3869
1126011000674	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1126011000675	ADP binding site [chemical binding]; other site
1126011000676	phosphagen binding site; other site
1126011000677	substrate specificity loop; other site
1126011000678	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1126011000679	Clp amino terminal domain; Region: Clp_N; pfam02861
1126011000680	Clp amino terminal domain; Region: Clp_N; pfam02861
1126011000681	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011000682	Walker A motif; other site
1126011000683	ATP binding site [chemical binding]; other site
1126011000684	Walker B motif; other site
1126011000685	arginine finger; other site
1126011000686	UvrB/uvrC motif; Region: UVR; pfam02151
1126011000687	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011000688	Walker A motif; other site
1126011000689	ATP binding site [chemical binding]; other site
1126011000690	Walker B motif; other site
1126011000691	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1126011000692	DNA repair protein RadA; Provisional; Region: PRK11823
1126011000693	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1126011000694	Walker A motif/ATP binding site; other site
1126011000695	ATP binding site [chemical binding]; other site
1126011000696	Walker B motif; other site
1126011000697	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1126011000698	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1126011000699	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1126011000700	putative active site [active]
1126011000701	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1126011000702	substrate binding site; other site
1126011000703	dimer interface; other site
1126011000704	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1126011000705	homotrimer interaction site [polypeptide binding]; other site
1126011000706	zinc binding site [ion binding]; other site
1126011000707	CDP-binding sites; other site
1126011000708	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1126011000709	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1126011000710	HIGH motif; other site
1126011000711	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1126011000712	active site
1126011000713	KMSKS motif; other site
1126011000714	serine O-acetyltransferase; Region: cysE; TIGR01172
1126011000715	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1126011000716	trimer interface [polypeptide binding]; other site
1126011000717	active site
1126011000718	substrate binding site [chemical binding]; other site
1126011000719	CoA binding site [chemical binding]; other site
1126011000720	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1126011000721	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1126011000722	active site
1126011000723	HIGH motif; other site
1126011000724	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1126011000725	KMSKS motif; other site
1126011000726	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1126011000727	tRNA binding surface [nucleotide binding]; other site
1126011000728	anticodon binding site; other site
1126011000729	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1126011000730	active site
1126011000731	metal binding site [ion binding]; metal-binding site
1126011000732	dimerization interface [polypeptide binding]; other site
1126011000733	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1126011000734	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1126011000735	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1126011000736	Predicted RNA-binding protein containing a PIN domain [General function prediction only]; Region: COG3688
1126011000737	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1126011000738	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1126011000739	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1126011000740	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1126011000741	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1126011000742	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1126011000743	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1126011000744	putative homodimer interface [polypeptide binding]; other site
1126011000745	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1126011000746	heterodimer interface [polypeptide binding]; other site
1126011000747	homodimer interface [polypeptide binding]; other site
1126011000748	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1126011000749	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1126011000750	23S rRNA interface [nucleotide binding]; other site
1126011000751	L7/L12 interface [polypeptide binding]; other site
1126011000752	putative thiostrepton binding site; other site
1126011000753	L25 interface [polypeptide binding]; other site
1126011000754	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1126011000755	mRNA/rRNA interface [nucleotide binding]; other site
1126011000756	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1126011000757	23S rRNA interface [nucleotide binding]; other site
1126011000758	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1126011000759	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1126011000760	core dimer interface [polypeptide binding]; other site
1126011000761	peripheral dimer interface [polypeptide binding]; other site
1126011000762	L10 interface [polypeptide binding]; other site
1126011000763	L11 interface [polypeptide binding]; other site
1126011000764	putative EF-Tu interaction site [polypeptide binding]; other site
1126011000765	putative EF-G interaction site [polypeptide binding]; other site
1126011000766	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1126011000767	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011000768	S-adenosylmethionine binding site [chemical binding]; other site
1126011000769	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1126011000770	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011000771	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011000772	DNA binding site [nucleotide binding]
1126011000773	domain linker motif; other site
1126011000774	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1126011000775	putative dimerization interface [polypeptide binding]; other site
1126011000776	putative ligand binding site [chemical binding]; other site
1126011000777	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1126011000778	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011000779	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1126011000780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000781	dimer interface [polypeptide binding]; other site
1126011000782	conserved gate region; other site
1126011000783	putative PBP binding loops; other site
1126011000784	ABC-ATPase subunit interface; other site
1126011000785	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011000786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000787	dimer interface [polypeptide binding]; other site
1126011000788	conserved gate region; other site
1126011000789	putative PBP binding loops; other site
1126011000790	ABC-ATPase subunit interface; other site
1126011000791	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1126011000792	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1126011000793	Ca binding site [ion binding]; other site
1126011000794	active site
1126011000795	catalytic site [active]
1126011000796	Alpha amylase catalytic domain found in sucrose phosphorylase (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase; cd11355
1126011000797	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1126011000798	active site
1126011000799	homodimer interface [polypeptide binding]; other site
1126011000800	catalytic site [active]
1126011000801	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1126011000802	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1126011000803	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1126011000804	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
1126011000805	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1126011000806	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1126011000807	RPB10 interaction site [polypeptide binding]; other site
1126011000808	RPB1 interaction site [polypeptide binding]; other site
1126011000809	RPB11 interaction site [polypeptide binding]; other site
1126011000810	RPB3 interaction site [polypeptide binding]; other site
1126011000811	RPB12 interaction site [polypeptide binding]; other site
1126011000812	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1126011000813	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1126011000814	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1126011000815	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1126011000816	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1126011000817	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1126011000818	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1126011000819	G-loop; other site
1126011000820	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1126011000821	DNA binding site [nucleotide binding]
1126011000822	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1126011000823	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1126011000824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000825	active site
1126011000826	motif I; other site
1126011000827	motif II; other site
1126011000828	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011000829	beta-galactosidase; Region: BGL; TIGR03356
1126011000830	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1126011000831	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1126011000832	Walker A/P-loop; other site
1126011000833	ATP binding site [chemical binding]; other site
1126011000834	Q-loop/lid; other site
1126011000835	ABC transporter signature motif; other site
1126011000836	Walker B; other site
1126011000837	D-loop; other site
1126011000838	H-loop/switch region; other site
1126011000839	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1126011000840	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1126011000841	Walker A/P-loop; other site
1126011000842	ATP binding site [chemical binding]; other site
1126011000843	Q-loop/lid; other site
1126011000844	ABC transporter signature motif; other site
1126011000845	Walker B; other site
1126011000846	D-loop; other site
1126011000847	H-loop/switch region; other site
1126011000848	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011000849	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011000850	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011000851	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000852	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000853	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000854	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000855	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000856	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011000857	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011000858	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011000859	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011000860	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011000861	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000862	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000863	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000864	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000865	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000866	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000867	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011000868	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011000869	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011000870	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011000871	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000872	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000873	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011000874	Leucine-rich repeats; other site
1126011000875	Substrate binding site [chemical binding]; other site
1126011000876	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000877	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000878	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000879	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000880	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011000881	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011000882	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011000883	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1126011000884	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1126011000885	metal binding site [ion binding]; metal-binding site
1126011000886	dimer interface [polypeptide binding]; other site
1126011000887	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011000888	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011000889	putative Zn2+ binding site [ion binding]; other site
1126011000890	putative DNA binding site [nucleotide binding]; other site
1126011000891	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1126011000892	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011000893	Zn binding site [ion binding]; other site
1126011000894	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1126011000895	Zn binding site [ion binding]; other site
1126011000896	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011000897	catalytic core [active]
1126011000898	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
1126011000899	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1126011000900	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1126011000901	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000902	dimer interface [polypeptide binding]; other site
1126011000903	conserved gate region; other site
1126011000904	ABC-ATPase subunit interface; other site
1126011000905	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011000906	Substrate binding site [chemical binding]; other site
1126011000907	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000908	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000909	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000910	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000911	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011000912	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1126011000913	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011000914	beta-galactosidase; Region: BGL; TIGR03356
1126011000915	sugar phosphate phosphatase; Provisional; Region: PRK10513
1126011000916	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000917	active site
1126011000918	motif I; other site
1126011000919	motif II; other site
1126011000920	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000921	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011000922	Coenzyme A binding pocket [chemical binding]; other site
1126011000923	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000924	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1126011000925	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1126011000926	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1126011000927	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000928	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1126011000929	active site
1126011000930	motif I; other site
1126011000931	motif II; other site
1126011000932	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011000933	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011000934	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011000935	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1126011000936	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1126011000937	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1126011000938	Walker A/P-loop; other site
1126011000939	ATP binding site [chemical binding]; other site
1126011000940	Q-loop/lid; other site
1126011000941	ABC transporter signature motif; other site
1126011000942	Walker B; other site
1126011000943	D-loop; other site
1126011000944	H-loop/switch region; other site
1126011000945	TOBE domain; Region: TOBE; pfam03459
1126011000946	potential frameshift: common BLAST hit: gi|226222915|ref|YP_002757022.1| anaerobic ribonucleoside triphosphate reductase
1126011000947	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1126011000948	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1126011000949	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011000950	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011000951	ligand binding site [chemical binding]; other site
1126011000952	flexible hinge region; other site
1126011000953	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1126011000954	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
1126011000955	putative active site [active]
1126011000956	catalytic triad [active]
1126011000957	putative dimer interface [polypeptide binding]; other site
1126011000958	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011000959	dimer interface [polypeptide binding]; other site
1126011000960	conserved gate region; other site
1126011000961	ABC-ATPase subunit interface; other site
1126011000962	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1126011000963	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1126011000964	Walker A/P-loop; other site
1126011000965	ATP binding site [chemical binding]; other site
1126011000966	Q-loop/lid; other site
1126011000967	ABC transporter signature motif; other site
1126011000968	Walker B; other site
1126011000969	D-loop; other site
1126011000970	H-loop/switch region; other site
1126011000971	NIL domain; Region: NIL; pfam09383
1126011000972	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1126011000973	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1126011000974	transaminase; Reviewed; Region: PRK08068
1126011000975	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011000976	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011000977	homodimer interface [polypeptide binding]; other site
1126011000978	catalytic residue [active]
1126011000979	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011000980	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011000981	active site
1126011000982	phosphorylation site [posttranslational modification]
1126011000983	intermolecular recognition site; other site
1126011000984	dimerization interface [polypeptide binding]; other site
1126011000985	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011000986	DNA binding site [nucleotide binding]
1126011000987	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1126011000988	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011000989	dimerization interface [polypeptide binding]; other site
1126011000990	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1126011000991	putative active site [active]
1126011000992	heme pocket [chemical binding]; other site
1126011000993	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011000994	dimer interface [polypeptide binding]; other site
1126011000995	phosphorylation site [posttranslational modification]
1126011000996	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011000997	ATP binding site [chemical binding]; other site
1126011000998	Mg2+ binding site [ion binding]; other site
1126011000999	G-X-G motif; other site
1126011001000	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
1126011001001	YycH protein; Region: YycH; pfam07435
1126011001002	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4853
1126011001003	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1126011001004	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1126011001005	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1126011001006	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1126011001007	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1126011001008	protein binding site [polypeptide binding]; other site
1126011001009	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1126011001010	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011001011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011001012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1126011001013	dimerization interface [polypeptide binding]; other site
1126011001014	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1126011001015	dimer interface [polypeptide binding]; other site
1126011001016	FMN binding site [chemical binding]; other site
1126011001017	NADPH bind site [chemical binding]; other site
1126011001018	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011001019	HTH domain; Region: HTH_11; pfam08279
1126011001020	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011001021	PRD domain; Region: PRD; pfam00874
1126011001022	PRD domain; Region: PRD; pfam00874
1126011001023	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011001024	active site
1126011001025	P-loop; other site
1126011001026	phosphorylation site [posttranslational modification]
1126011001027	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001028	active site
1126011001029	phosphorylation site [posttranslational modification]
1126011001030	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011001031	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011001032	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011001033	active site
1126011001034	P-loop; other site
1126011001035	phosphorylation site [posttranslational modification]
1126011001036	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011001037	beta-galactosidase; Region: BGL; TIGR03356
1126011001038	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011001039	methionine cluster; other site
1126011001040	active site
1126011001041	phosphorylation site [posttranslational modification]
1126011001042	metal binding site [ion binding]; metal-binding site
1126011001043	potential frameshift: common BLAST hit: gi|46906545|ref|YP_012934.1| type II restriction enzyme Sau3AI
1126011001044	potential frameshift: common BLAST hit: gi|46906547|ref|YP_012936.1| C-5 cytosine-specific DNA methylase
1126011001045	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1126011001046	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1126011001047	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011001048	catalytic residue [active]
1126011001049	uncharacterized YdjC-like family proteins from bacteria; Region: YdjC_like_1; cd10805
1126011001050	putative active site [active]
1126011001051	YdjC motif; other site
1126011001052	Mg binding site [ion binding]; other site
1126011001053	putative homodimer interface [polypeptide binding]; other site
1126011001054	Putative transcription activator [Transcription]; Region: TenA; COG0819
1126011001055	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1126011001056	substrate binding site [chemical binding]; other site
1126011001057	multimerization interface [polypeptide binding]; other site
1126011001058	ATP binding site [chemical binding]; other site
1126011001059	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1126011001060	dimer interface [polypeptide binding]; other site
1126011001061	substrate binding site [chemical binding]; other site
1126011001062	ATP binding site [chemical binding]; other site
1126011001063	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1126011001064	thiamine phosphate binding site [chemical binding]; other site
1126011001065	active site
1126011001066	pyrophosphate binding site [ion binding]; other site
1126011001067	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011001068	beta-galactosidase; Region: BGL; TIGR03356
1126011001069	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001070	Protein of unknown function (DUF2910); Region: DUF2910; pfam11139
1126011001071	Protein of unknown function (DUF1696); Region: DUF1696; pfam08000
1126011001072	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
1126011001073	putative catalytic site [active]
1126011001074	putative metal binding site [ion binding]; other site
1126011001075	putative phosphate binding site [ion binding]; other site
1126011001076	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011001077	non-specific DNA binding site [nucleotide binding]; other site
1126011001078	salt bridge; other site
1126011001079	sequence-specific DNA binding site [nucleotide binding]; other site
1126011001080	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1126011001081	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011001082	non-specific DNA binding site [nucleotide binding]; other site
1126011001083	salt bridge; other site
1126011001084	sequence-specific DNA binding site [nucleotide binding]; other site
1126011001085	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1126011001086	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001087	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001088	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001089	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001090	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001091	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001092	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001093	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001094	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001095	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001096	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001097	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001098	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001099	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001100	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001101	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001102	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001103	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001104	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001105	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011001106	Leucine-rich repeats; other site
1126011001107	Substrate binding site [chemical binding]; other site
1126011001108	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001109	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001110	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001111	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001112	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011001113	Leucine-rich repeats; other site
1126011001114	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001115	Substrate binding site [chemical binding]; other site
1126011001116	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001117	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001118	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001119	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001120	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001121	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001122	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001123	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001124	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001125	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
1126011001126	Protein of unknown function (DUF3130; Region: DUF3130; pfam11328
1126011001127	LXG domain of WXG superfamily; Region: LXG; pfam04740
1126011001128	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
1126011001129	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1126011001130	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1126011001131	TPP-binding site [chemical binding]; other site
1126011001132	dimer interface [polypeptide binding]; other site
1126011001133	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1126011001134	PYR/PP interface [polypeptide binding]; other site
1126011001135	dimer interface [polypeptide binding]; other site
1126011001136	TPP binding site [chemical binding]; other site
1126011001137	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011001138	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1126011001139	active site
1126011001140	intersubunit interactions; other site
1126011001141	catalytic residue [active]
1126011001142	short chain dehydrogenase; Provisional; Region: PRK06841
1126011001143	classical (c) SDRs; Region: SDR_c; cd05233
1126011001144	NAD(P) binding site [chemical binding]; other site
1126011001145	active site
1126011001146	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1126011001147	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1126011001148	substrate binding site [chemical binding]; other site
1126011001149	dimer interface [polypeptide binding]; other site
1126011001150	catalytic triad [active]
1126011001151	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1126011001152	DAK2 domain; Region: Dak2; cl03685
1126011001153	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
1126011001154	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1126011001155	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
1126011001156	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011001157	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011001158	putative DNA binding site [nucleotide binding]; other site
1126011001159	putative Zn2+ binding site [ion binding]; other site
1126011001160	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011001161	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011001162	Coenzyme A binding pocket [chemical binding]; other site
1126011001163	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011001164	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1126011001165	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001166	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001167	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001168	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1126011001169	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1126011001170	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1126011001171	acyl-activating enzyme (AAE) consensus motif; other site
1126011001172	acyl-activating enzyme (AAE) consensus motif; other site
1126011001173	AMP binding site [chemical binding]; other site
1126011001174	active site
1126011001175	CoA binding site [chemical binding]; other site
1126011001176	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
1126011001177	L-aspartate oxidase; Provisional; Region: PRK06175
1126011001178	putative oxidoreductase; Provisional; Region: PRK10206
1126011001179	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011001180	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1126011001181	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001182	active site
1126011001183	phosphorylation site [posttranslational modification]
1126011001184	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1126011001185	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011001186	active site
1126011001187	P-loop; other site
1126011001188	phosphorylation site [posttranslational modification]
1126011001189	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011001190	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1126011001191	intersubunit interface [polypeptide binding]; other site
1126011001192	active site
1126011001193	zinc binding site [ion binding]; other site
1126011001194	Na+ binding site [ion binding]; other site
1126011001195	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011001196	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1126011001197	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011001198	potential frameshift: common BLAST hit: gi|46906601|ref|YP_012990.1| S51 family peptidase
1126011001199	Predicted transcriptional regulator [Transcription]; Region: COG2378
1126011001200	HTH domain; Region: HTH_11; pfam08279
1126011001201	WYL domain; Region: WYL; pfam13280
1126011001202	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
1126011001203	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
1126011001204	nudix motif; other site
1126011001205	hypothetical protein; Provisional; Region: PRK12378
1126011001206	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1126011001207	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1126011001208	PhnA protein; Region: PhnA; pfam03831
1126011001209	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011001210	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011001211	DNA-binding site [nucleotide binding]; DNA binding site
1126011001212	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1126011001213	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011001214	beta-galactosidase; Region: BGL; TIGR03356
1126011001215	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011001216	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1126011001217	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011001218	active site
1126011001219	P-loop; other site
1126011001220	phosphorylation site [posttranslational modification]
1126011001221	Predicted transcriptional regulator [Transcription]; Region: COG2378
1126011001222	HTH domain; Region: HTH_11; pfam08279
1126011001223	WYL domain; Region: WYL; pfam13280
1126011001224	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1126011001225	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011001226	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1126011001227	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011001228	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1126011001229	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1126011001230	tetrameric interface [polypeptide binding]; other site
1126011001231	NAD binding site [chemical binding]; other site
1126011001232	catalytic residues [active]
1126011001233	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1126011001234	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1126011001235	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1126011001236	substrate binding site [chemical binding]; other site
1126011001237	ATP binding site [chemical binding]; other site
1126011001238	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1126011001239	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1126011001240	PYR/PP interface [polypeptide binding]; other site
1126011001241	dimer interface [polypeptide binding]; other site
1126011001242	TPP binding site [chemical binding]; other site
1126011001243	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1126011001244	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1126011001245	TPP-binding site; other site
1126011001246	Uncharacterized conserved protein [Function unknown]; Region: COG5646
1126011001247	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
1126011001248	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1126011001249	ligand binding site [chemical binding]; other site
1126011001250	active site
1126011001251	UGI interface [polypeptide binding]; other site
1126011001252	catalytic site [active]
1126011001253	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
1126011001254	hypothetical protein; Provisional; Region: PRK13665
1126011001255	Bacterial SH3 domain; Region: SH3_3; cl17532
1126011001256	NlpC/P60 family; Region: NLPC_P60; pfam00877
1126011001257	potential frameshift: common BLAST hit: gi|46906626|ref|YP_013015.1| acetyltransferase
1126011001258	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1126011001259	pyrroline-5-carboxylate reductase; Region: PLN02688
1126011001260	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011001261	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001262	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1126011001263	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011001264	DNA-binding site [nucleotide binding]; DNA binding site
1126011001265	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1126011001266	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011001267	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011001268	Walker A/P-loop; other site
1126011001269	ATP binding site [chemical binding]; other site
1126011001270	Q-loop/lid; other site
1126011001271	ABC transporter signature motif; other site
1126011001272	Walker B; other site
1126011001273	D-loop; other site
1126011001274	H-loop/switch region; other site
1126011001275	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011001276	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1126011001277	FtsX-like permease family; Region: FtsX; pfam02687
1126011001278	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_6; cd08899
1126011001279	putative hydrophobic ligand binding site [chemical binding]; other site
1126011001280	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001281	active site
1126011001282	phosphorylation site [posttranslational modification]
1126011001283	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011001284	active site
1126011001285	P-loop; other site
1126011001286	phosphorylation site [posttranslational modification]
1126011001287	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011001288	alpha-mannosidase; Provisional; Region: PRK09819
1126011001289	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1126011001290	active site
1126011001291	metal binding site [ion binding]; metal-binding site
1126011001292	catalytic site [active]
1126011001293	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1126011001294	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011001295	HTH domain; Region: HTH_11; pfam08279
1126011001296	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011001297	PRD domain; Region: PRD; pfam00874
1126011001298	PRD domain; Region: PRD; pfam00874
1126011001299	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011001300	active site
1126011001301	P-loop; other site
1126011001302	phosphorylation site [posttranslational modification]
1126011001303	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001304	active site
1126011001305	phosphorylation site [posttranslational modification]
1126011001306	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1126011001307	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
1126011001308	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011001309	putative metal binding site [ion binding]; other site
1126011001310	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4835
1126011001311	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
1126011001312	trimer interface [polypeptide binding]; other site
1126011001313	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011001314	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001315	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011001316	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001317	Leucine-rich repeats; other site
1126011001318	Substrate binding site [chemical binding]; other site
1126011001319	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001320	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001321	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001322	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001323	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001324	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001325	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001326	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001327	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001328	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001329	phosphoenolpyruvate synthase; Validated; Region: PRK06241
1126011001330	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1126011001331	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1126011001332	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1126011001333	ZIP Zinc transporter; Region: Zip; pfam02535
1126011001334	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1126011001335	Catalytic NodB homology domain of Clostridium thermocellum acetylxylan esterase and its bacterial homologs; Region: CE4_CtAXE_like; cd10954
1126011001336	NodB motif; other site
1126011001337	active site
1126011001338	catalytic site [active]
1126011001339	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011001340	non-specific DNA binding site [nucleotide binding]; other site
1126011001341	salt bridge; other site
1126011001342	sequence-specific DNA binding site [nucleotide binding]; other site
1126011001343	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
1126011001344	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011001345	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001346	active site
1126011001347	motif I; other site
1126011001348	motif II; other site
1126011001349	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001350	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1126011001351	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011001352	HTH domain; Region: HTH_11; pfam08279
1126011001353	PRD domain; Region: PRD; pfam00874
1126011001354	PRD domain; Region: PRD; pfam00874
1126011001355	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011001356	active site
1126011001357	P-loop; other site
1126011001358	phosphorylation site [posttranslational modification]
1126011001359	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001360	active site
1126011001361	phosphorylation site [posttranslational modification]
1126011001362	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001363	active site
1126011001364	phosphorylation site [posttranslational modification]
1126011001365	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011001366	active site
1126011001367	P-loop; other site
1126011001368	phosphorylation site [posttranslational modification]
1126011001369	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011001370	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
1126011001371	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1126011001372	active site
1126011001373	metal binding site [ion binding]; metal-binding site
1126011001374	catalytic site [active]
1126011001375	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
1126011001376	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011001377	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011001378	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1126011001379	dimerization interface [polypeptide binding]; other site
1126011001380	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1126011001381	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1126011001382	active site
1126011001383	substrate binding site [chemical binding]; other site
1126011001384	trimer interface [polypeptide binding]; other site
1126011001385	CoA binding site [chemical binding]; other site
1126011001386	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1126011001387	classical (c) SDRs; Region: SDR_c; cd05233
1126011001388	NAD(P) binding site [chemical binding]; other site
1126011001389	active site
1126011001390	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1126011001391	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
1126011001392	RHS Repeat; Region: RHS_repeat; pfam05593
1126011001393	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1126011001394	RHS Repeat; Region: RHS_repeat; pfam05593
1126011001395	RHS Repeat; Region: RHS_repeat; pfam05593
1126011001396	RHS Repeat; Region: RHS_repeat; pfam05593
1126011001397	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1126011001398	HEAT repeats; Region: HEAT_2; pfam13646
1126011001399	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011001400	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001401	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011001402	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001403	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001404	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001405	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001406	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001407	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001408	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001409	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001410	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001411	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001412	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
1126011001413	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011001414	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001415	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011001416	Leucine rich repeat; Region: LRR_8; pfam13855
1126011001417	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001418	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011001419	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001420	SH3-like domain; Region: SH3_8; pfam13457
1126011001421	Predicted transcriptional regulator [Transcription]; Region: COG1959
1126011001422	Transcriptional regulator; Region: Rrf2; pfam02082
1126011001423	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1126011001424	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1126011001425	NAD(P) binding site [chemical binding]; other site
1126011001426	active site
1126011001427	Uncharacterized protein containing a NRPS condensation (elongation) domain [General function prediction only]; Region: COG4908
1126011001428	Protein of unknown function (DUF2004); Region: DUF2004; pfam09406
1126011001429	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
1126011001430	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1126011001431	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1126011001432	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1126011001433	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1126011001434	Protein of unknown function (DUF4240); Region: DUF4240; pfam14024
1126011001435	Signal peptide peptidase; Region: Peptidase_A22B; cl01342
1126011001436	Predicted membrane protein [Function unknown]; Region: COG3619
1126011001437	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
1126011001438	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1126011001439	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1126011001440	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
1126011001441	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1126011001442	Protein of unknown function DUF58; Region: DUF58; pfam01882
1126011001443	MoxR-like ATPases [General function prediction only]; Region: COG0714
1126011001444	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011001445	Walker A motif; other site
1126011001446	ATP binding site [chemical binding]; other site
1126011001447	Walker B motif; other site
1126011001448	arginine finger; other site
1126011001449	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1126011001450	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1126011001451	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
1126011001452	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1126011001453	Na binding site [ion binding]; other site
1126011001454	Uncharacterized conserved protein [Function unknown]; Region: COG3535
1126011001455	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1126011001456	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011001457	nucleotide binding site [chemical binding]; other site
1126011001458	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1126011001459	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011001460	potential frameshift: common BLAST hit: gi|226224630|ref|YP_002758737.1| membrane associated lipoprotein
1126011001461	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1126011001462	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001463	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001464	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001465	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1126011001466	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001467	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001468	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001469	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001470	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011001471	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011001472	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011001473	Zn2+ binding site [ion binding]; other site
1126011001474	Mg2+ binding site [ion binding]; other site
1126011001475	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
1126011001476	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1126011001477	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011001478	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
1126011001479	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
1126011001480	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1126011001481	FeS/SAM binding site; other site
1126011001482	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1126011001483	heme-degrading monooxygenase IsdG; Provisional; Region: PRK13316
1126011001484	LXG domain of WXG superfamily; Region: LXG; pfam04740
1126011001485	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1126011001486	putative FMN binding site [chemical binding]; other site
1126011001487	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1126011001488	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1126011001489	nudix motif; other site
1126011001490	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011001491	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011001492	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1126011001493	putative dimerization interface [polypeptide binding]; other site
1126011001494	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1126011001495	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1126011001496	active site
1126011001497	FMN binding site [chemical binding]; other site
1126011001498	substrate binding site [chemical binding]; other site
1126011001499	putative catalytic residue [active]
1126011001500	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1126011001501	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011001502	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011001503	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1126011001504	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1126011001505	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1126011001506	shikimate binding site; other site
1126011001507	NAD(P) binding site [chemical binding]; other site
1126011001508	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1126011001509	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1126011001510	active site
1126011001511	catalytic residue [active]
1126011001512	dimer interface [polypeptide binding]; other site
1126011001513	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011001514	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011001515	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1126011001516	dimerization interface [polypeptide binding]; other site
1126011001517	substrate binding pocket [chemical binding]; other site
1126011001518	Predicted acyl esterases [General function prediction only]; Region: COG2936
1126011001519	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
1126011001520	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
1126011001521	active site
1126011001522	catalytic triad [active]
1126011001523	oxyanion hole [active]
1126011001524	EamA-like transporter family; Region: EamA; pfam00892
1126011001525	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1126011001526	EamA-like transporter family; Region: EamA; pfam00892
1126011001527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4224
1126011001528	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1126011001529	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1126011001530	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1126011001531	substrate binding site [chemical binding]; other site
1126011001532	hexamer interface [polypeptide binding]; other site
1126011001533	metal binding site [ion binding]; metal-binding site
1126011001534	Transaldolase [Carbohydrate transport and metabolism]; Region: MipB; COG0176
1126011001535	catalytic residue [active]
1126011001536	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011001537	PRD domain; Region: PRD; pfam00874
1126011001538	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011001539	active site
1126011001540	P-loop; other site
1126011001541	phosphorylation site [posttranslational modification]
1126011001542	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001543	active site
1126011001544	phosphorylation site [posttranslational modification]
1126011001545	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1126011001546	putative active site [active]
1126011001547	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011001548	active site
1126011001549	phosphorylation site [posttranslational modification]
1126011001550	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1126011001551	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1126011001552	substrate binding site [chemical binding]; other site
1126011001553	hexamer interface [polypeptide binding]; other site
1126011001554	metal binding site [ion binding]; metal-binding site
1126011001555	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1126011001556	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1126011001557	putative NAD(P) binding site [chemical binding]; other site
1126011001558	catalytic Zn binding site [ion binding]; other site
1126011001559	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1126011001560	active site
1126011001561	P-loop; other site
1126011001562	phosphorylation site [posttranslational modification]
1126011001563	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1126011001564	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1126011001565	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1126011001566	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1126011001567	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011001568	active site
1126011001569	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1126011001570	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1126011001571	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1126011001572	catalytic triad [active]
1126011001573	conserved hypothetical protein; Region: lin0512_fam; TIGR02058
1126011001574	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011001575	MarR family; Region: MarR_2; pfam12802
1126011001576	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001577	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001578	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1126011001579	Ligand Binding Site [chemical binding]; other site
1126011001580	Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]; Region: PgsA; COG2843
1126011001581	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1126011001582	putative active site [active]
1126011001583	putative metal binding site [ion binding]; other site
1126011001584	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001585	catalytic core [active]
1126011001586	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001587	Predicted membrane protein [Function unknown]; Region: COG3759
1126011001588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011001589	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011001590	putative substrate translocation pore; other site
1126011001591	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1126011001592	non-specific DNA interactions [nucleotide binding]; other site
1126011001593	DNA binding site [nucleotide binding]
1126011001594	sequence specific DNA binding site [nucleotide binding]; other site
1126011001595	putative cAMP binding site [chemical binding]; other site
1126011001596	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011001597	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1126011001598	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1126011001599	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1126011001600	NAD binding site [chemical binding]; other site
1126011001601	sugar binding site [chemical binding]; other site
1126011001602	divalent metal binding site [ion binding]; other site
1126011001603	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011001604	dimer interface [polypeptide binding]; other site
1126011001605	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011001606	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011001607	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011001608	putative active site [active]
1126011001609	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1126011001610	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1126011001611	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1126011001612	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1126011001613	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1126011001614	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1126011001615	DNA binding residues [nucleotide binding]
1126011001616	dimer interface [polypeptide binding]; other site
1126011001617	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1126011001618	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1126011001619	Uncharacterized protein conserved in bacteria (DUF2334); Region: DUF2334; pfam10096
1126011001620	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1126011001621	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1126011001622	DXD motif; other site
1126011001623	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1126011001624	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1126011001625	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1126011001626	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011001627	S-adenosylmethionine binding site [chemical binding]; other site
1126011001628	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
1126011001629	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
1126011001630	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011001631	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011001632	DNA binding site [nucleotide binding]
1126011001633	domain linker motif; other site
1126011001634	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1126011001635	putative dimerization interface [polypeptide binding]; other site
1126011001636	putative ligand binding site [chemical binding]; other site
1126011001637	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1126011001638	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1126011001639	NAD binding site [chemical binding]; other site
1126011001640	sugar binding site [chemical binding]; other site
1126011001641	divalent metal binding site [ion binding]; other site
1126011001642	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011001643	dimer interface [polypeptide binding]; other site
1126011001644	allantoate amidohydrolase; Reviewed; Region: PRK09290
1126011001645	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1126011001646	active site
1126011001647	metal binding site [ion binding]; metal-binding site
1126011001648	dimer interface [polypeptide binding]; other site
1126011001649	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1126011001650	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
1126011001651	metal binding site [ion binding]; metal-binding site
1126011001652	putative dimer interface [polypeptide binding]; other site
1126011001653	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
1126011001654	Beta-lactamase; Region: Beta-lactamase; pfam00144
1126011001655	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1126011001656	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1126011001657	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1126011001658	intersubunit interface [polypeptide binding]; other site
1126011001659	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
1126011001660	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1126011001661	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1126011001662	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1126011001663	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
1126011001664	Glucitol operon activator protein (GutM); Region: GutM; cl01890
1126011001665	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
1126011001666	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011001667	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
1126011001668	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1126011001669	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1126011001670	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011001671	Antagonist of mitotic exit network protein 1; Region: AMN1; cl15308
1126011001672	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001673	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001674	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001675	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011001676	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1126011001677	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1126011001678	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1126011001679	FOG: CBS domain [General function prediction only]; Region: COG0517
1126011001680	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1126011001681	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1126011001682	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1126011001683	dimer interface [polypeptide binding]; other site
1126011001684	active site
1126011001685	metal binding site [ion binding]; metal-binding site
1126011001686	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1126011001687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011001688	putative substrate translocation pore; other site
1126011001689	POT family; Region: PTR2; pfam00854
1126011001690	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001691	catalytic core [active]
1126011001692	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001693	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001694	catalytic core [active]
1126011001695	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011001696	3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706
1126011001697	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1126011001698	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1126011001699	Cl binding site [ion binding]; other site
1126011001700	oligomer interface [polypeptide binding]; other site
1126011001701	glutamate dehydrogenase; Provisional; Region: PRK09414
1126011001702	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1126011001703	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1126011001704	NAD(P) binding site [chemical binding]; other site
1126011001705	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1126011001706	metal binding site [ion binding]; metal-binding site
1126011001707	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1126011001708	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1126011001709	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1126011001710	substrate binding site [chemical binding]; other site
1126011001711	glutamase interaction surface [polypeptide binding]; other site
1126011001712	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1126011001713	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1126011001714	catalytic residues [active]
1126011001715	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1126011001716	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1126011001717	putative active site [active]
1126011001718	oxyanion strand; other site
1126011001719	catalytic triad [active]
1126011001720	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1126011001721	putative active site pocket [active]
1126011001722	4-fold oligomerization interface [polypeptide binding]; other site
1126011001723	metal binding residues [ion binding]; metal-binding site
1126011001724	3-fold/trimer interface [polypeptide binding]; other site
1126011001725	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1126011001726	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1126011001727	NAD binding site [chemical binding]; other site
1126011001728	dimerization interface [polypeptide binding]; other site
1126011001729	product binding site; other site
1126011001730	substrate binding site [chemical binding]; other site
1126011001731	zinc binding site [ion binding]; other site
1126011001732	catalytic residues [active]
1126011001733	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
1126011001734	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1126011001735	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
1126011001736	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1126011001737	dimer interface [polypeptide binding]; other site
1126011001738	motif 1; other site
1126011001739	active site
1126011001740	motif 2; other site
1126011001741	motif 3; other site
1126011001742	histidinol-phosphatase; Reviewed; Region: PRK08123
1126011001743	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1126011001744	active site
1126011001745	dimer interface [polypeptide binding]; other site
1126011001746	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1126011001747	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1126011001748	DNA binding site [nucleotide binding]
1126011001749	active site
1126011001750	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1126011001751	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1126011001752	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011001753	beta-galactosidase; Region: BGL; TIGR03356
1126011001754	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011001755	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011001756	DNA-binding site [nucleotide binding]; DNA binding site
1126011001757	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1126011001758	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001759	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001760	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1126011001761	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1126011001762	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1126011001763	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
1126011001764	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
1126011001765	Predicted esterase [General function prediction only]; Region: COG0400
1126011001766	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1126011001767	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1126011001768	putative RNA binding site [nucleotide binding]; other site
1126011001769	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011001770	S-adenosylmethionine binding site [chemical binding]; other site
1126011001771	invasion associated secreted endopeptidase; Provisional; Region: PRK13914
1126011001772	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011001773	Bacterial SH3 domain; Region: SH3_3; pfam08239
1126011001774	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011001775	NlpC/P60 family; Region: NLPC_P60; pfam00877
1126011001776	preprotein translocase subunit SecA; Reviewed; Region: PRK09200
1126011001777	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1126011001778	ATP binding site [chemical binding]; other site
1126011001779	putative Mg++ binding site [ion binding]; other site
1126011001780	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1126011001781	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1126011001782	nucleotide binding region [chemical binding]; other site
1126011001783	ATP-binding site [chemical binding]; other site
1126011001784	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1126011001785	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1126011001786	WxL domain surface cell wall-binding; Region: WxL; pfam13731
1126011001787	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
1126011001788	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
1126011001789	UreD urease accessory protein; Region: UreD; cl00530
1126011001790	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1126011001791	DNA photolyase; Region: DNA_photolyase; pfam00875
1126011001792	Predicted membrane protein [Function unknown]; Region: COG4852
1126011001793	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
1126011001794	DAK2 domain; Region: Dak2; pfam02734
1126011001795	EDD domain protein, DegV family; Region: DegV; TIGR00762
1126011001796	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1126011001797	Steroid 5-alpha reductase family enzyme [General function prediction only]; Region: COG3752
1126011001798	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1126011001799	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
1126011001800	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
1126011001801	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
1126011001802	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1126011001803	homodimer interface [polypeptide binding]; other site
1126011001804	substrate-cofactor binding pocket; other site
1126011001805	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011001806	catalytic residue [active]
1126011001807	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
1126011001808	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011001809	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1126011001810	ligand binding site [chemical binding]; other site
1126011001811	flexible hinge region; other site
1126011001812	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011001813	BioY family; Region: BioY; pfam02632
1126011001814	Predicted transcriptional regulators [Transcription]; Region: COG1695
1126011001815	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1126011001816	Predicted membrane protein [Function unknown]; Region: COG4709
1126011001817	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1126011001818	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1126011001819	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1126011001820	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1126011001821	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1126011001822	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011001823	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1126011001824	Coenzyme A binding pocket [chemical binding]; other site
1126011001825	Tic20-like protein; Region: Tic20; pfam09685
1126011001826	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1126011001827	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1126011001828	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1126011001829	MarR family; Region: MarR_2; pfam12802
1126011001830	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011001831	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011001832	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011001833	Walker A/P-loop; other site
1126011001834	ATP binding site [chemical binding]; other site
1126011001835	Q-loop/lid; other site
1126011001836	ABC transporter signature motif; other site
1126011001837	Walker B; other site
1126011001838	D-loop; other site
1126011001839	H-loop/switch region; other site
1126011001840	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011001841	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011001842	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1126011001843	Walker A/P-loop; other site
1126011001844	ATP binding site [chemical binding]; other site
1126011001845	Q-loop/lid; other site
1126011001846	ABC transporter signature motif; other site
1126011001847	Walker B; other site
1126011001848	D-loop; other site
1126011001849	H-loop/switch region; other site
1126011001850	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1126011001851	active site residue [active]
1126011001852	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011001853	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1126011001854	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1126011001855	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1126011001856	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011001857	putative DNA binding site [nucleotide binding]; other site
1126011001858	putative Zn2+ binding site [ion binding]; other site
1126011001859	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1126011001860	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1126011001861	putative NAD(P) binding site [chemical binding]; other site
1126011001862	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
1126011001863	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1126011001864	Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: COG4781
1126011001865	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1126011001866	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
1126011001867	putative active site [active]
1126011001868	catalytic site [active]
1126011001869	putative metal binding site [ion binding]; other site
1126011001870	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1126011001871	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1126011001872	active site
1126011001873	ATP binding site [chemical binding]; other site
1126011001874	substrate binding site [chemical binding]; other site
1126011001875	activation loop (A-loop); other site
1126011001876	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1126011001877	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1126011001878	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
1126011001879	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1126011001880	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011001881	Coenzyme A binding pocket [chemical binding]; other site
1126011001882	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1126011001883	active site
1126011001884	catalytic triad [active]
1126011001885	oxyanion hole [active]
1126011001886	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
1126011001887	domain interaction interfaces [polypeptide binding]; other site
1126011001888	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
1126011001889	domain interaction interfaces [polypeptide binding]; other site
1126011001890	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
1126011001891	domain interaction interfaces [polypeptide binding]; other site
1126011001892	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
1126011001893	domain interaction interfaces [polypeptide binding]; other site
1126011001894	Isochorismatase family; Region: Isochorismatase; pfam00857
1126011001895	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1126011001896	catalytic triad [active]
1126011001897	conserved cis-peptide bond; other site
1126011001898	potential frameshift: common BLAST hit: gi|46906875|ref|YP_013264.1| PTS system IIA component domain-containing protein
1126011001899	potential frameshift: common BLAST hit: gi|46906875|ref|YP_013264.1| PTS system IIA component domain-containing protein
1126011001900	potential frameshift: common BLAST hit: gi|46906875|ref|YP_013264.1| PTS system IIA component domain-containing protein
1126011001901	potential frameshift: common BLAST hit: gi|46906875|ref|YP_013264.1| PTS system IIA component domain-containing protein
1126011001902	potential frameshift: common BLAST hit: gi|46906875|ref|YP_013264.1| PTS system IIA component domain-containing protein
1126011001903	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1126011001904	potential frameshift: common BLAST hit: gi|347548054|ref|YP_004854382.1| putative PTS system, fructose-specific IIC component
1126011001905	potential frameshift: common BLAST hit: gi|284994098|ref|YP_003415866.1| putative fructose-like permease EIIC subunit 2
1126011001906	potential frameshift: common BLAST hit: gi|347548056|ref|YP_004854384.1| putative tagatose 6-phosphate kinase
1126011001907	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1126011001908	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001909	motif II; other site
1126011001910	Predicted transcriptional regulator [Transcription]; Region: COG1959
1126011001911	Transcriptional regulator; Region: Rrf2; pfam02082
1126011001912	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011001913	S-adenosylmethionine binding site [chemical binding]; other site
1126011001914	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1126011001915	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
1126011001916	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011001917	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011001918	active site
1126011001919	catalytic tetrad [active]
1126011001920	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1126011001921	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011001922	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001923	motif II; other site
1126011001924	Transaldolase [Carbohydrate transport and metabolism]; Region: MipB; COG0176
1126011001925	catalytic residue [active]
1126011001926	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1126011001927	Sulfatase; Region: Sulfatase; pfam00884
1126011001928	amino acid transporter; Region: 2A0306; TIGR00909
1126011001929	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1126011001930	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1126011001931	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
1126011001932	putative metal binding site [ion binding]; other site
1126011001933	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1126011001934	active site
1126011001935	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1126011001936	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1126011001937	Cl binding site [ion binding]; other site
1126011001938	oligomer interface [polypeptide binding]; other site
1126011001939	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1126011001940	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011001941	DNA-binding site [nucleotide binding]; DNA binding site
1126011001942	Predicted membrane protein [Function unknown]; Region: COG1511
1126011001943	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1126011001944	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011001945	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1126011001946	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011001947	DNA-binding site [nucleotide binding]; DNA binding site
1126011001948	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1126011001949	Predicted integral membrane protein [Function unknown]; Region: COG5523
1126011001950	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1126011001951	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1126011001952	active site
1126011001953	metal binding site [ion binding]; metal-binding site
1126011001954	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1126011001955	AAA domain; Region: AAA_13; pfam13166
1126011001956	Predicted membrane protein [Function unknown]; Region: COG2322
1126011001957	Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair]; Region: COG2231
1126011001958	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1126011001959	minor groove reading motif; other site
1126011001960	helix-hairpin-helix signature motif; other site
1126011001961	substrate binding pocket [chemical binding]; other site
1126011001962	active site
1126011001963	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011001964	non-specific DNA binding site [nucleotide binding]; other site
1126011001965	salt bridge; other site
1126011001966	sequence-specific DNA binding site [nucleotide binding]; other site
1126011001967	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1126011001968	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1126011001969	Transposase; Region: HTH_Tnp_1; cl17663
1126011001970	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011001971	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001972	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011001973	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1126011001974	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1126011001975	dimer interface [polypeptide binding]; other site
1126011001976	substrate binding site [chemical binding]; other site
1126011001977	ATP binding site [chemical binding]; other site
1126011001978	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011001979	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001980	active site
1126011001981	motif I; other site
1126011001982	motif II; other site
1126011001983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011001984	maltose O-acetyltransferase; Provisional; Region: PRK10092
1126011001985	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1126011001986	active site
1126011001987	substrate binding site [chemical binding]; other site
1126011001988	trimer interface [polypeptide binding]; other site
1126011001989	CoA binding site [chemical binding]; other site
1126011001990	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1126011001991	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011001992	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
1126011001993	Walker A/P-loop; other site
1126011001994	ATP binding site [chemical binding]; other site
1126011001995	Q-loop/lid; other site
1126011001996	ABC transporter signature motif; other site
1126011001997	Walker B; other site
1126011001998	D-loop; other site
1126011001999	H-loop/switch region; other site
1126011002000	inner membrane transport permease; Provisional; Region: PRK15066
1126011002001	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1126011002002	oxidoreductase; Provisional; Region: PRK07985
1126011002003	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1126011002004	NAD(P) binding site [chemical binding]; other site
1126011002005	active site
1126011002006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
1126011002007	Predicted membrane protein [Function unknown]; Region: COG3152
1126011002008	DNA binding domain of the motility gene repressor (MogR); Region: MogR_DNAbind; pfam12181
1126011002009	Flagellar biosynthesis pathway, component FliP [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliP; COG1338
1126011002010	Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987
1126011002011	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
1126011002012	Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; COG1377
1126011002013	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1126011002014	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
1126011002015	FHIPEP family; Region: FHIPEP; pfam00771
1126011002016	flagellar biosynthesis regulator FlhF; Provisional; Region: PRK12726
1126011002017	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1126011002018	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12819
1126011002019	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1126011002020	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1126011002021	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1126011002022	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1126011002023	Protein of unknown function (DUF3964); Region: DUF3964; pfam13107
1126011002024	flagellar motor protein MotA; Validated; Region: PRK08124
1126011002025	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1126011002026	flagellar motor protein MotB; Reviewed; Region: motB; PRK07734
1126011002027	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1126011002028	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1126011002029	ligand binding site [chemical binding]; other site
1126011002030	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1126011002031	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1126011002032	putative metal binding site; other site
1126011002033	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011002034	binding surface
1126011002035	TPR motif; other site
1126011002036	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1126011002037	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1126011002038	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011002039	active site
1126011002040	phosphorylation site [posttranslational modification]
1126011002041	intermolecular recognition site; other site
1126011002042	dimerization interface [polypeptide binding]; other site
1126011002043	flagellin; Provisional; Region: PRK12805
1126011002044	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1126011002045	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1126011002046	Response regulator receiver domain; Region: Response_reg; pfam00072
1126011002047	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011002048	active site
1126011002049	phosphorylation site [posttranslational modification]
1126011002050	intermolecular recognition site; other site
1126011002051	dimerization interface [polypeptide binding]; other site
1126011002052	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1126011002053	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1126011002054	putative binding surface; other site
1126011002055	active site
1126011002056	P2 response regulator binding domain; Region: P2; pfam07194
1126011002057	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1126011002058	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011002059	ATP binding site [chemical binding]; other site
1126011002060	Mg2+ binding site [ion binding]; other site
1126011002061	G-X-G motif; other site
1126011002062	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1126011002063	flagellar motor switch protein; Validated; Region: PRK06788
1126011002064	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1126011002065	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK11911
1126011002066	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1126011002067	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
1126011002068	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1126011002069	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1126011002070	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1126011002071	flagellar motor switch protein; Validated; Region: PRK06789
1126011002072	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1126011002073	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1126011002074	flagellar motor switch protein; Reviewed; Region: PRK06782
1126011002075	CheC-like family; Region: CheC; pfam04509
1126011002076	CheC-like family; Region: CheC; pfam04509
1126011002077	Chemotaxis phosphatase CheX; Region: CheX; cl15816
1126011002078	CheC-like family; Region: CheC; pfam04509
1126011002079	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1126011002080	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1126011002081	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06799
1126011002082	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1126011002083	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08073
1126011002084	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1126011002085	flagellar capping protein; Validated; Region: fliD; PRK06798
1126011002086	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1126011002087	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1126011002088	Flagellin-specific chaperone FliS [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliS; COG1516
1126011002089	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK06797
1126011002090	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgC; COG1558
1126011002091	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1126011002092	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK01699
1126011002093	Flagellar basal body M-ring protein [Cell motility and secretion]; Region: fliF; COG1766
1126011002094	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1126011002095	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1126011002096	Flagellar motor switch protein [Cell motility and secretion]; Region: FliG; COG1536
1126011002097	FliG C-terminal domain; Region: FliG_C; pfam01706
1126011002098	flagellar assembly protein H; Validated; Region: fliH; PRK06800
1126011002099	Flagellar assembly protein FliH; Region: FliH; pfam02108
1126011002100	flagellum-specific ATP synthase; Validated; Region: fliI; PRK06793
1126011002101	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1126011002102	Walker A motif; other site
1126011002103	ATP binding site [chemical binding]; other site
1126011002104	Walker B motif; other site
1126011002105	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1126011002106	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1126011002107	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1126011002108	catalytic residue [active]
1126011002109	Predicted transcriptional regulators [Transcription]; Region: COG1695
1126011002110	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1126011002111	Protein of unknown function (DUF1048); Region: DUF1048; pfam06304
1126011002112	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
1126011002113	pyruvate oxidase; Provisional; Region: PRK08611
1126011002114	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1126011002115	PYR/PP interface [polypeptide binding]; other site
1126011002116	dimer interface [polypeptide binding]; other site
1126011002117	tetramer interface [polypeptide binding]; other site
1126011002118	TPP binding site [chemical binding]; other site
1126011002119	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1126011002120	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1126011002121	TPP-binding site [chemical binding]; other site
1126011002122	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1126011002123	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1126011002124	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011002125	dimerization interface [polypeptide binding]; other site
1126011002126	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1126011002127	dimer interface [polypeptide binding]; other site
1126011002128	putative CheW interface [polypeptide binding]; other site
1126011002129	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
1126011002130	putative active site [active]
1126011002131	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1126011002132	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1126011002133	glutaminase active site [active]
1126011002134	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1126011002135	dimer interface [polypeptide binding]; other site
1126011002136	active site
1126011002137	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1126011002138	dimer interface [polypeptide binding]; other site
1126011002139	active site
1126011002140	FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196
1126011002141	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1126011002142	active site
1126011002143	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
1126011002144	GIY-YIG motif/motif A; other site
1126011002145	Leucine rich repeat; Region: LRR_8; pfam13855
1126011002146	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002147	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002148	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002149	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1126011002150	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011002151	non-specific DNA binding site [nucleotide binding]; other site
1126011002152	salt bridge; other site
1126011002153	sequence-specific DNA binding site [nucleotide binding]; other site
1126011002154	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011002155	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011002156	ligand binding site [chemical binding]; other site
1126011002157	flexible hinge region; other site
1126011002158	Predicted transcriptional regulators [Transcription]; Region: COG1725
1126011002159	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002160	DNA-binding site [nucleotide binding]; DNA binding site
1126011002161	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1126011002162	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011002163	Walker A/P-loop; other site
1126011002164	ATP binding site [chemical binding]; other site
1126011002165	Q-loop/lid; other site
1126011002166	ABC transporter signature motif; other site
1126011002167	Walker B; other site
1126011002168	D-loop; other site
1126011002169	H-loop/switch region; other site
1126011002170	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011002171	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011002172	Walker A/P-loop; other site
1126011002173	ATP binding site [chemical binding]; other site
1126011002174	Q-loop/lid; other site
1126011002175	ABC transporter signature motif; other site
1126011002176	Walker B; other site
1126011002177	D-loop; other site
1126011002178	H-loop/switch region; other site
1126011002179	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011002180	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1126011002181	FtsX-like permease family; Region: FtsX; pfam02687
1126011002182	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1126011002183	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011002184	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1126011002185	ligand binding site [chemical binding]; other site
1126011002186	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1126011002187	non-specific DNA interactions [nucleotide binding]; other site
1126011002188	DNA binding site [nucleotide binding]
1126011002189	sequence specific DNA binding site [nucleotide binding]; other site
1126011002190	putative cAMP binding site [chemical binding]; other site
1126011002191	SnoaL-like domain; Region: SnoaL_4; pfam13577
1126011002192	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
1126011002193	active site
1126011002194	catalytic triad [active]
1126011002195	oxyanion hole [active]
1126011002196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011002197	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011002198	Walker A/P-loop; other site
1126011002199	ATP binding site [chemical binding]; other site
1126011002200	Q-loop/lid; other site
1126011002201	ABC transporter signature motif; other site
1126011002202	Walker B; other site
1126011002203	D-loop; other site
1126011002204	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1126011002205	H-loop/switch region; other site
1126011002206	active site
1126011002207	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
1126011002208	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1126011002209	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1126011002210	Zn binding site [ion binding]; other site
1126011002211	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1126011002212	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011002213	Zn binding site [ion binding]; other site
1126011002214	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1126011002215	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011002216	Zn binding site [ion binding]; other site
1126011002217	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1126011002218	Zn binding site [ion binding]; other site
1126011002219	Predicted esterase [General function prediction only]; Region: COG0400
1126011002220	putative hydrolase; Provisional; Region: PRK11460
1126011002221	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1126011002222	GTPases [General function prediction only]; Region: HflX; COG2262
1126011002223	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1126011002224	HflX GTPase family; Region: HflX; cd01878
1126011002225	G1 box; other site
1126011002226	GTP/Mg2+ binding site [chemical binding]; other site
1126011002227	Switch I region; other site
1126011002228	G2 box; other site
1126011002229	G3 box; other site
1126011002230	Switch II region; other site
1126011002231	G4 box; other site
1126011002232	G5 box; other site
1126011002233	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1126011002234	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1126011002235	putative active site [active]
1126011002236	putative metal binding site [ion binding]; other site
1126011002237	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1126011002238	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1126011002239	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1126011002240	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1126011002241	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002242	DNA-binding site [nucleotide binding]; DNA binding site
1126011002243	Yhfp putative quinone oxidoreductases; Region: MDR_yhfp_like; cd08289
1126011002244	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1126011002245	putative NADP binding site [chemical binding]; other site
1126011002246	putative dimer interface [polypeptide binding]; other site
1126011002247	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1126011002248	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1126011002249	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011002250	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011002251	nucleotide binding site [chemical binding]; other site
1126011002252	Predicted membrane protein [Function unknown]; Region: COG4811
1126011002253	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1126011002254	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1126011002255	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1126011002256	active site
1126011002257	phosphorylation site [posttranslational modification]
1126011002258	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011002259	active pocket/dimerization site; other site
1126011002260	active site
1126011002261	phosphorylation site [posttranslational modification]
1126011002262	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1126011002263	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011002264	Walker A motif; other site
1126011002265	ATP binding site [chemical binding]; other site
1126011002266	Walker B motif; other site
1126011002267	arginine finger; other site
1126011002268	Transcriptional antiterminator [Transcription]; Region: COG3933
1126011002269	PRD domain; Region: PRD; pfam00874
1126011002270	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011002271	active pocket/dimerization site; other site
1126011002272	active site
1126011002273	phosphorylation site [posttranslational modification]
1126011002274	PRD domain; Region: PRD; pfam00874
1126011002275	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
1126011002276	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1126011002277	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1126011002278	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1126011002279	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1126011002280	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1126011002281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
1126011002282	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1126011002283	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1126011002284	Leucine rich repeat; Region: LRR_8; pfam13855
1126011002285	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002286	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002287	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002288	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002289	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002290	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011002291	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1126011002292	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1126011002293	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1126011002294	putative deacylase active site [active]
1126011002295	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1126011002296	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1126011002297	active site
1126011002298	catalytic triad [active]
1126011002299	dimer interface [polypeptide binding]; other site
1126011002300	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1126011002301	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1126011002302	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1126011002303	NAD binding site [chemical binding]; other site
1126011002304	substrate binding site [chemical binding]; other site
1126011002305	putative active site [active]
1126011002306	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1126011002307	EamA-like transporter family; Region: EamA; pfam00892
1126011002308	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1126011002309	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1126011002310	MarR family; Region: MarR_2; pfam12802
1126011002311	lysine transporter; Provisional; Region: PRK10836
1126011002312	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1126011002313	PAS domain; Region: PAS_9; pfam13426
1126011002314	putative active site [active]
1126011002315	heme pocket [chemical binding]; other site
1126011002316	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011002317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
1126011002318	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1126011002319	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1126011002320	synthetase active site [active]
1126011002321	NTP binding site [chemical binding]; other site
1126011002322	metal binding site [ion binding]; metal-binding site
1126011002323	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1126011002324	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1126011002325	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011002326	non-specific DNA binding site [nucleotide binding]; other site
1126011002327	salt bridge; other site
1126011002328	sequence-specific DNA binding site [nucleotide binding]; other site
1126011002329	Cupin domain; Region: Cupin_2; pfam07883
1126011002330	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1126011002331	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1126011002332	Walker A/P-loop; other site
1126011002333	ATP binding site [chemical binding]; other site
1126011002334	Q-loop/lid; other site
1126011002335	ABC transporter signature motif; other site
1126011002336	Walker B; other site
1126011002337	D-loop; other site
1126011002338	H-loop/switch region; other site
1126011002339	TOBE domain; Region: TOBE_2; pfam08402
1126011002340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002341	dimer interface [polypeptide binding]; other site
1126011002342	conserved gate region; other site
1126011002343	putative PBP binding loops; other site
1126011002344	ABC-ATPase subunit interface; other site
1126011002345	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1126011002346	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002347	dimer interface [polypeptide binding]; other site
1126011002348	conserved gate region; other site
1126011002349	putative PBP binding loops; other site
1126011002350	ABC-ATPase subunit interface; other site
1126011002351	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1126011002352	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1126011002353	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
1126011002354	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1126011002355	active site
1126011002356	zinc binding site [ion binding]; other site
1126011002357	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1126011002358	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011002359	Zn2+ binding site [ion binding]; other site
1126011002360	Mg2+ binding site [ion binding]; other site
1126011002361	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011002362	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011002363	nucleotide binding site [chemical binding]; other site
1126011002364	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1126011002365	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1126011002366	FMN binding site [chemical binding]; other site
1126011002367	substrate binding site [chemical binding]; other site
1126011002368	putative catalytic residue [active]
1126011002369	Protein of unknown function (DUF3130; Region: DUF3130; pfam11328
1126011002370	LXG domain of WXG superfamily; Region: LXG; pfam04740
1126011002371	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1126011002372	dimer interface [polypeptide binding]; other site
1126011002373	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011002374	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1126011002375	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1126011002376	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011002377	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1126011002378	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011002379	motif II; other site
1126011002380	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1126011002381	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011002382	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011002383	Coenzyme A binding pocket [chemical binding]; other site
1126011002384	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1126011002385	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011002386	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011002387	DNA binding residues [nucleotide binding]
1126011002388	putative dimer interface [polypeptide binding]; other site
1126011002389	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011002390	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011002391	active site
1126011002392	catalytic tetrad [active]
1126011002393	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1126011002394	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
1126011002395	homodimer interface [polypeptide binding]; other site
1126011002396	catalytic residues [active]
1126011002397	NAD binding site [chemical binding]; other site
1126011002398	substrate binding pocket [chemical binding]; other site
1126011002399	flexible flap; other site
1126011002400	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1126011002401	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1126011002402	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1126011002403	PhoU domain; Region: PhoU; pfam01895
1126011002404	PhoU domain; Region: PhoU; pfam01895
1126011002405	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1126011002406	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1126011002407	dimer interface [polypeptide binding]; other site
1126011002408	PYR/PP interface [polypeptide binding]; other site
1126011002409	TPP binding site [chemical binding]; other site
1126011002410	substrate binding site [chemical binding]; other site
1126011002411	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1126011002412	Domain of unknown function; Region: EKR; smart00890
1126011002413	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1126011002414	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1126011002415	TPP-binding site [chemical binding]; other site
1126011002416	dimer interface [polypeptide binding]; other site
1126011002417	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1126011002418	Predicted permeases [General function prediction only]; Region: COG0679
1126011002419	Helix-turn-helix domain; Region: HTH_28; pfam13518
1126011002420	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011002421	non-specific DNA binding site [nucleotide binding]; other site
1126011002422	salt bridge; other site
1126011002423	sequence-specific DNA binding site [nucleotide binding]; other site
1126011002424	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1126011002425	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002426	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011002427	Predicted membrane protein [Function unknown]; Region: COG3223
1126011002428	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011002429	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011002430	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1126011002431	Walker A/P-loop; other site
1126011002432	ATP binding site [chemical binding]; other site
1126011002433	Q-loop/lid; other site
1126011002434	ABC transporter signature motif; other site
1126011002435	Walker B; other site
1126011002436	D-loop; other site
1126011002437	H-loop/switch region; other site
1126011002438	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1126011002439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002440	putative substrate translocation pore; other site
1126011002441	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002443	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011002444	putative substrate translocation pore; other site
1126011002445	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011002446	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011002447	putative DNA binding site [nucleotide binding]; other site
1126011002448	putative Zn2+ binding site [ion binding]; other site
1126011002449	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1126011002450	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1126011002451	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011002452	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1126011002453	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011002454	motif II; other site
1126011002455	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1126011002456	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002457	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002458	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002459	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002460	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002461	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002462	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011002463	Predicted membrane protein [Function unknown]; Region: COG3326
1126011002464	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1126011002465	homotrimer interaction site [polypeptide binding]; other site
1126011002466	putative active site [active]
1126011002467	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1126011002468	substrate binding site [chemical binding]; other site
1126011002469	zinc-binding site [ion binding]; other site
1126011002470	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1126011002471	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1126011002472	GIY-YIG motif/motif A; other site
1126011002473	active site
1126011002474	catalytic site [active]
1126011002475	putative DNA binding site [nucleotide binding]; other site
1126011002476	metal binding site [ion binding]; metal-binding site
1126011002477	UvrB/uvrC motif; Region: UVR; pfam02151
1126011002478	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1126011002479	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1126011002480	substrate binding pocket [chemical binding]; other site
1126011002481	membrane-bound complex binding site; other site
1126011002482	hinge residues; other site
1126011002483	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1126011002484	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002485	dimer interface [polypeptide binding]; other site
1126011002486	conserved gate region; other site
1126011002487	putative PBP binding loops; other site
1126011002488	ABC-ATPase subunit interface; other site
1126011002489	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1126011002490	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1126011002491	Walker A/P-loop; other site
1126011002492	ATP binding site [chemical binding]; other site
1126011002493	Q-loop/lid; other site
1126011002494	ABC transporter signature motif; other site
1126011002495	Walker B; other site
1126011002496	D-loop; other site
1126011002497	H-loop/switch region; other site
1126011002498	amidase; Provisional; Region: PRK11910
1126011002499	Amidase; Region: Amidase; cl11426
1126011002500	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011002501	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011002502	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1126011002503	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1126011002504	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1126011002505	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1126011002506	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1126011002507	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1126011002508	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1126011002509	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1126011002510	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
1126011002511	Esterase/lipase [General function prediction only]; Region: COG1647
1126011002512	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011002513	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011002514	DNA binding site [nucleotide binding]
1126011002515	domain linker motif; other site
1126011002516	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_1; cd06277
1126011002517	putative dimerization interface [polypeptide binding]; other site
1126011002518	putative ligand binding site [chemical binding]; other site
1126011002519	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1126011002520	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011002521	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1126011002522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002523	dimer interface [polypeptide binding]; other site
1126011002524	conserved gate region; other site
1126011002525	putative PBP binding loops; other site
1126011002526	ABC-ATPase subunit interface; other site
1126011002527	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011002528	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002529	dimer interface [polypeptide binding]; other site
1126011002530	conserved gate region; other site
1126011002531	ABC-ATPase subunit interface; other site
1126011002532	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1126011002533	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1126011002534	Ca binding site [ion binding]; other site
1126011002535	active site
1126011002536	catalytic site [active]
1126011002537	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
1126011002538	Predicted glycosylase [Carbohydrate transport and metabolism]; Region: COG2152
1126011002539	active site
1126011002540	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1126011002541	active site
1126011002542	substrate binding site [chemical binding]; other site
1126011002543	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1126011002544	metal binding site [ion binding]; metal-binding site
1126011002545	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1126011002546	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1126011002547	ATP binding site [chemical binding]; other site
1126011002548	Mg++ binding site [ion binding]; other site
1126011002549	motif III; other site
1126011002550	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011002551	nucleotide binding region [chemical binding]; other site
1126011002552	ATP-binding site [chemical binding]; other site
1126011002553	Predicted membrane protein [Function unknown]; Region: COG4708
1126011002554	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
1126011002555	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4367
1126011002556	Predicted transcriptional regulators [Transcription]; Region: COG1733
1126011002557	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1126011002558	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1126011002559	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002560	putative substrate translocation pore; other site
1126011002561	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011002562	PRD domain; Region: PRD; pfam00874
1126011002563	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011002564	active site
1126011002565	P-loop; other site
1126011002566	phosphorylation site [posttranslational modification]
1126011002567	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011002568	active site
1126011002569	phosphorylation site [posttranslational modification]
1126011002570	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011002571	methionine cluster; other site
1126011002572	active site
1126011002573	phosphorylation site [posttranslational modification]
1126011002574	metal binding site [ion binding]; metal-binding site
1126011002575	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011002576	active site
1126011002577	P-loop; other site
1126011002578	phosphorylation site [posttranslational modification]
1126011002579	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011002580	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011002581	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1126011002582	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1126011002583	active site
1126011002584	trimer interface [polypeptide binding]; other site
1126011002585	allosteric site; other site
1126011002586	active site lid [active]
1126011002587	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1126011002588	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011002589	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011002590	active site
1126011002591	catalytic tetrad [active]
1126011002592	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1126011002593	Collagen binding domain; Region: Collagen_bind; pfam05737
1126011002594	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011002595	Uncharacterized conserved protein [Function unknown]; Region: COG3402
1126011002596	Predicted membrane protein [Function unknown]; Region: COG3428
1126011002597	Bacterial PH domain; Region: DUF304; pfam03703
1126011002598	Bacterial PH domain; Region: DUF304; pfam03703
1126011002599	Bacterial PH domain; Region: DUF304; pfam03703
1126011002600	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
1126011002601	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1126011002602	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1126011002603	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1126011002604	active site
1126011002605	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1126011002606	dimer interface [polypeptide binding]; other site
1126011002607	substrate binding site [chemical binding]; other site
1126011002608	catalytic residues [active]
1126011002609	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
1126011002610	PemK-like protein; Region: PemK; pfam02452
1126011002611	Rsbr N terminal; Region: Rsbr_N; pfam08678
1126011002612	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011002613	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011002614	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1126011002615	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
1126011002616	ATP binding site [chemical binding]; other site
1126011002617	Mg2+ binding site [ion binding]; other site
1126011002618	G-X-G motif; other site
1126011002619	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1126011002620	Phosphoserine phosphatase RsbU, N-terminal domain; Region: RsbU_N; pfam08673
1126011002621	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1126011002622	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1126011002623	anti sigma factor interaction site; other site
1126011002624	regulatory phosphorylation site [posttranslational modification]; other site
1126011002625	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1126011002626	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011002627	ATP binding site [chemical binding]; other site
1126011002628	Mg2+ binding site [ion binding]; other site
1126011002629	G-X-G motif; other site
1126011002630	RNA polymerase sigma factor SigB; Validated; Region: PRK08583
1126011002631	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1126011002632	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1126011002633	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1126011002634	DNA binding residues [nucleotide binding]
1126011002635	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
1126011002636	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1126011002637	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1126011002638	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1126011002639	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1126011002640	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1126011002641	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1126011002642	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1126011002643	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1126011002644	RNA binding site [nucleotide binding]; other site
1126011002645	hypothetical protein; Provisional; Region: PRK04351
1126011002646	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1126011002647	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
1126011002648	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1126011002649	Uncharacterized conserved protein [Function unknown]; Region: COG5646
1126011002650	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011002651	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011002652	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011002653	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002654	DNA-binding site [nucleotide binding]; DNA binding site
1126011002655	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1126011002656	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1126011002657	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
1126011002658	Predicted protein tyrosine phosphatase [General function prediction only]; Region: COG5350
1126011002659	glutathione reductase; Validated; Region: PRK06116
1126011002660	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011002661	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011002662	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1126011002663	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011002664	catalytic core [active]
1126011002665	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1126011002666	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1126011002667	Predicted transcriptional regulators [Transcription]; Region: COG1725
1126011002668	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002669	DNA-binding site [nucleotide binding]; DNA binding site
1126011002670	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1126011002671	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1126011002672	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1126011002673	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1126011002674	tetramerization interface [polypeptide binding]; other site
1126011002675	NAD(P) binding site [chemical binding]; other site
1126011002676	catalytic residues [active]
1126011002677	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1126011002678	active site
1126011002679	P-loop; other site
1126011002680	phosphorylation site [posttranslational modification]
1126011002681	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011002682	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011002683	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011002684	methionine cluster; other site
1126011002685	active site
1126011002686	phosphorylation site [posttranslational modification]
1126011002687	metal binding site [ion binding]; metal-binding site
1126011002688	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011002689	beta-galactosidase; Region: BGL; TIGR03356
1126011002690	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011002691	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011002692	PRD domain; Region: PRD; pfam00874
1126011002693	PRD domain; Region: PRD; pfam00874
1126011002694	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011002695	active site
1126011002696	phosphorylation site [posttranslational modification]
1126011002697	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011002698	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1126011002699	ABC transporter; Region: ABC_tran_2; pfam12848
1126011002700	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011002701	heme ABC exporter, ATP-binding protein CcmA; Region: ccmA; TIGR01189
1126011002702	Predicted permeases [General function prediction only]; Region: COG0701
1126011002703	Predicted membrane protein [Function unknown]; Region: COG3689
1126011002704	pantothenate kinase; Provisional; Region: PRK05439
1126011002705	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1126011002706	ATP-binding site [chemical binding]; other site
1126011002707	CoA-binding site [chemical binding]; other site
1126011002708	Mg2+-binding site [ion binding]; other site
1126011002709	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1126011002710	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011002711	Walker A/P-loop; other site
1126011002712	ATP binding site [chemical binding]; other site
1126011002713	Q-loop/lid; other site
1126011002714	ABC transporter signature motif; other site
1126011002715	Walker B; other site
1126011002716	D-loop; other site
1126011002717	H-loop/switch region; other site
1126011002718	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1126011002719	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1126011002720	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011002721	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011002722	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1126011002723	Domain of unknown function (DUF373); Region: DUF373; cl12079
1126011002724	Sulfatase; Region: Sulfatase; pfam00884
1126011002725	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1126011002726	active site
1126011002727	DNA binding site [nucleotide binding]
1126011002728	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
1126011002729	active site
1126011002730	catalytic site [active]
1126011002731	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1126011002732	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1126011002733	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1126011002734	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1126011002735	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1126011002736	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1126011002737	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1126011002738	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1126011002739	epoxyqueuosine reductase; Region: TIGR00276
1126011002740	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1126011002741	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1126011002742	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1126011002743	dimer interface [polypeptide binding]; other site
1126011002744	FMN binding site [chemical binding]; other site
1126011002745	NADPH bind site [chemical binding]; other site
1126011002746	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1126011002747	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1126011002748	active site
1126011002749	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1126011002750	HSP90 family protein; Provisional; Region: PRK14083
1126011002751	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011002752	ATP binding site [chemical binding]; other site
1126011002753	Mg2+ binding site [ion binding]; other site
1126011002754	G-X-G motif; other site
1126011002755	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1126011002756	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1126011002757	dimerization interface [polypeptide binding]; other site
1126011002758	DPS ferroxidase diiron center [ion binding]; other site
1126011002759	ion pore; other site
1126011002760	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4841
1126011002761	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1126011002762	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011002763	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1126011002764	Protein of unknown function (DUF3006); Region: DUF3006; pfam11213
1126011002765	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1126011002766	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002767	putative substrate translocation pore; other site
1126011002768	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1126011002769	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002770	DNA-binding site [nucleotide binding]; DNA binding site
1126011002771	FCD domain; Region: FCD; pfam07729
1126011002772	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1126011002773	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1126011002774	Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814
1126011002775	PGAP1-like protein; Region: PGAP1; pfam07819
1126011002776	Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814
1126011002777	Protein of unknown function (DUF4064); Region: DUF4064; pfam13273
1126011002778	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1126011002779	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1126011002780	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1126011002781	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1126011002782	active site
1126011002783	dimer interface [polypeptide binding]; other site
1126011002784	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1126011002785	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1126011002786	active site
1126011002787	trimer interface [polypeptide binding]; other site
1126011002788	allosteric site; other site
1126011002789	active site lid [active]
1126011002790	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1126011002791	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011002792	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011002793	DNA-binding site [nucleotide binding]; DNA binding site
1126011002794	UTRA domain; Region: UTRA; pfam07702
1126011002795	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1126011002796	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1126011002797	Mg++ binding site [ion binding]; other site
1126011002798	putative catalytic motif [active]
1126011002799	substrate binding site [chemical binding]; other site
1126011002800	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1126011002801	Peptidase family U32; Region: Peptidase_U32; pfam01136
1126011002802	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1126011002803	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1126011002804	Peptidase family U32; Region: Peptidase_U32; pfam01136
1126011002805	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1126011002806	heat shock protein HtpX; Provisional; Region: PRK04897
1126011002807	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1126011002808	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
1126011002809	catalytic residues [active]
1126011002810	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
1126011002811	putative active site [active]
1126011002812	putative metal binding residues [ion binding]; other site
1126011002813	signature motif; other site
1126011002814	putative triphosphate binding site [ion binding]; other site
1126011002815	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011002816	TPR motif; other site
1126011002817	binding surface
1126011002818	Tetratrico peptide repeat; Region: TPR_5; pfam12688
1126011002819	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1126011002820	synthetase active site [active]
1126011002821	NTP binding site [chemical binding]; other site
1126011002822	metal binding site [ion binding]; metal-binding site
1126011002823	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
1126011002824	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1126011002825	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1126011002826	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1126011002827	active site
1126011002828	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594
1126011002829	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1126011002830	NAD binding site [chemical binding]; other site
1126011002831	homotetramer interface [polypeptide binding]; other site
1126011002832	homodimer interface [polypeptide binding]; other site
1126011002833	substrate binding site [chemical binding]; other site
1126011002834	active site
1126011002835	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
1126011002836	DltD N-terminal region; Region: DltD_N; pfam04915
1126011002837	DltD central region; Region: DltD_M; pfam04918
1126011002838	DltD C-terminal region; Region: DltD_C; pfam04914
1126011002839	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
1126011002840	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
1126011002841	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
1126011002842	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
1126011002843	acyl-activating enzyme (AAE) consensus motif; other site
1126011002844	AMP binding site [chemical binding]; other site
1126011002845	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
1126011002846	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1126011002847	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011002848	active site
1126011002849	dimer interface [polypeptide binding]; other site
1126011002850	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011002851	Coenzyme A binding pocket [chemical binding]; other site
1126011002852	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1126011002853	Putative esterase; Region: Esterase; pfam00756
1126011002854	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1126011002855	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1126011002856	homodimer interface [polypeptide binding]; other site
1126011002857	substrate-cofactor binding pocket; other site
1126011002858	catalytic residue [active]
1126011002859	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1126011002860	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011002861	Walker A/P-loop; other site
1126011002862	ATP binding site [chemical binding]; other site
1126011002863	Q-loop/lid; other site
1126011002864	ABC transporter signature motif; other site
1126011002865	Walker B; other site
1126011002866	D-loop; other site
1126011002867	H-loop/switch region; other site
1126011002868	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1126011002869	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1126011002870	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011002871	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011002872	putative substrate translocation pore; other site
1126011002873	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1126011002874	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
1126011002875	putative oligomer interface [polypeptide binding]; other site
1126011002876	putative active site [active]
1126011002877	metal binding site [ion binding]; metal-binding site
1126011002878	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1126011002879	catalytic residues [active]
1126011002880	dimer interface [polypeptide binding]; other site
1126011002881	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1126011002882	LytTr DNA-binding domain; Region: LytTR; pfam04397
1126011002883	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011002884	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011002885	Walker A/P-loop; other site
1126011002886	ATP binding site [chemical binding]; other site
1126011002887	Q-loop/lid; other site
1126011002888	ABC transporter signature motif; other site
1126011002889	Walker B; other site
1126011002890	D-loop; other site
1126011002891	H-loop/switch region; other site
1126011002892	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cl09829
1126011002893	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1126011002894	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1126011002895	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1126011002896	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1126011002897	G1 box; other site
1126011002898	putative GEF interaction site [polypeptide binding]; other site
1126011002899	GTP/Mg2+ binding site [chemical binding]; other site
1126011002900	Switch I region; other site
1126011002901	G2 box; other site
1126011002902	G3 box; other site
1126011002903	Switch II region; other site
1126011002904	G4 box; other site
1126011002905	G5 box; other site
1126011002906	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1126011002907	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011002908	MarR family; Region: MarR_2; cl17246
1126011002909	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1126011002910	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1126011002911	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1126011002912	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1126011002913	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1126011002914	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1126011002915	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1126011002916	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1126011002917	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1126011002918	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1126011002919	DNA binding site [nucleotide binding]
1126011002920	active site
1126011002921	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1126011002922	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011002923	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1126011002924	Walker A motif; other site
1126011002925	ATP binding site [chemical binding]; other site
1126011002926	Walker B motif; other site
1126011002927	arginine finger; other site
1126011002928	UvrB/uvrC motif; Region: UVR; pfam02151
1126011002929	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011002930	Walker A motif; other site
1126011002931	ATP binding site [chemical binding]; other site
1126011002932	Walker B motif; other site
1126011002933	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1126011002934	CAAX protease self-immunity; Region: Abi; pfam02517
1126011002935	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
1126011002936	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1126011002937	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1126011002938	nucleotide binding site [chemical binding]; other site
1126011002939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4873
1126011002940	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1126011002941	dimerization domain swap beta strand [polypeptide binding]; other site
1126011002942	regulatory protein interface [polypeptide binding]; other site
1126011002943	active site
1126011002944	regulatory phosphorylation site [posttranslational modification]; other site
1126011002945	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1126011002946	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1126011002947	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1126011002948	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1126011002949	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1126011002950	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1126011002951	putative active site [active]
1126011002952	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1126011002953	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1126011002954	aminotransferase A; Validated; Region: PRK07683
1126011002955	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011002956	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011002957	homodimer interface [polypeptide binding]; other site
1126011002958	catalytic residue [active]
1126011002959	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4703
1126011002960	FOG: CBS domain [General function prediction only]; Region: COG0517
1126011002961	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
1126011002962	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011002963	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011002964	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1126011002965	dimerization interface [polypeptide binding]; other site
1126011002966	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1126011002967	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1126011002968	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1126011002969	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1126011002970	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1126011002971	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
1126011002972	metal binding site [ion binding]; metal-binding site
1126011002973	putative dimer interface [polypeptide binding]; other site
1126011002974	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1126011002975	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1126011002976	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
1126011002977	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011002978	Walker A/P-loop; other site
1126011002979	ATP binding site [chemical binding]; other site
1126011002980	Q-loop/lid; other site
1126011002981	ABC transporter signature motif; other site
1126011002982	Walker B; other site
1126011002983	D-loop; other site
1126011002984	H-loop/switch region; other site
1126011002985	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1126011002986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011002987	dimer interface [polypeptide binding]; other site
1126011002988	conserved gate region; other site
1126011002989	putative PBP binding loops; other site
1126011002990	ABC-ATPase subunit interface; other site
1126011002991	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
1126011002992	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1126011002993	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1126011002994	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1126011002995	HPr interaction site; other site
1126011002996	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1126011002997	active site
1126011002998	phosphorylation site [posttranslational modification]
1126011002999	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1126011003000	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1126011003001	S1 domain; Region: S1_2; pfam13509
1126011003002	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1126011003003	RNA binding site [nucleotide binding]; other site
1126011003004	Predicted membrane protein [Function unknown]; Region: COG4758
1126011003005	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
1126011003006	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1126011003007	Histidine kinase; Region: HisKA_3; pfam07730
1126011003008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011003009	ATP binding site [chemical binding]; other site
1126011003010	Mg2+ binding site [ion binding]; other site
1126011003011	G-X-G motif; other site
1126011003012	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1126011003013	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011003014	active site
1126011003015	phosphorylation site [posttranslational modification]
1126011003016	intermolecular recognition site; other site
1126011003017	dimerization interface [polypeptide binding]; other site
1126011003018	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1126011003019	DNA binding residues [nucleotide binding]
1126011003020	dimerization interface [polypeptide binding]; other site
1126011003021	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1126011003022	TrkA-N domain; Region: TrkA_N; pfam02254
1126011003023	TrkA-C domain; Region: TrkA_C; pfam02080
1126011003024	Predicted membrane protein [Function unknown]; Region: COG1289
1126011003025	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1126011003026	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1126011003027	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1126011003028	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1126011003029	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1126011003030	hypothetical protein; Provisional; Region: PRK13667
1126011003031	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011003032	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011003033	active site
1126011003034	motif I; other site
1126011003035	motif II; other site
1126011003036	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011003037	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011003038	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011003039	DNA binding site [nucleotide binding]
1126011003040	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1126011003041	ligand binding site [chemical binding]; other site
1126011003042	dimerization interface [polypeptide binding]; other site
1126011003043	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
1126011003044	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1126011003045	trimer interface [polypeptide binding]; other site
1126011003046	substrate binding site [chemical binding]; other site
1126011003047	Mn binding site [ion binding]; other site
1126011003048	transketolase; Reviewed; Region: PRK05899
1126011003049	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1126011003050	TPP-binding site [chemical binding]; other site
1126011003051	dimer interface [polypeptide binding]; other site
1126011003052	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1126011003053	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1126011003054	PYR/PP interface [polypeptide binding]; other site
1126011003055	dimer interface [polypeptide binding]; other site
1126011003056	TPP binding site [chemical binding]; other site
1126011003057	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011003058	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
1126011003059	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1126011003060	nucleotide binding site [chemical binding]; other site
1126011003061	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1126011003062	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1126011003063	active site turn [active]
1126011003064	phosphorylation site [posttranslational modification]
1126011003065	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1126011003066	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1126011003067	HPr interaction site; other site
1126011003068	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1126011003069	active site
1126011003070	phosphorylation site [posttranslational modification]
1126011003071	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
1126011003072	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
1126011003073	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1126011003074	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1126011003075	GTP binding site; other site
1126011003076	ATP-binding cassette domain of the molybdenum transport system; Region: ABC_ModC_molybdenum_transporter; cd03297
1126011003077	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1126011003078	Walker A/P-loop; other site
1126011003079	ATP binding site [chemical binding]; other site
1126011003080	Q-loop/lid; other site
1126011003081	ABC transporter signature motif; other site
1126011003082	Walker B; other site
1126011003083	D-loop; other site
1126011003084	H-loop/switch region; other site
1126011003085	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011003086	dimer interface [polypeptide binding]; other site
1126011003087	conserved gate region; other site
1126011003088	putative PBP binding loops; other site
1126011003089	ABC-ATPase subunit interface; other site
1126011003090	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1126011003091	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1126011003092	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1126011003093	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1126011003094	dimer interface [polypeptide binding]; other site
1126011003095	putative functional site; other site
1126011003096	putative MPT binding site; other site
1126011003097	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1126011003098	Walker A motif; other site
1126011003099	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1126011003100	MoaE homodimer interface [polypeptide binding]; other site
1126011003101	MoaD interaction [polypeptide binding]; other site
1126011003102	active site residues [active]
1126011003103	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1126011003104	MoaE interaction surface [polypeptide binding]; other site
1126011003105	MoeB interaction surface [polypeptide binding]; other site
1126011003106	thiocarboxylated glycine; other site
1126011003107	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1126011003108	trimer interface [polypeptide binding]; other site
1126011003109	dimer interface [polypeptide binding]; other site
1126011003110	putative active site [active]
1126011003111	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1126011003112	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1126011003113	FeS/SAM binding site; other site
1126011003114	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1126011003115	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1126011003116	MPT binding site; other site
1126011003117	trimer interface [polypeptide binding]; other site
1126011003118	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1126011003119	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1126011003120	ATP binding site [chemical binding]; other site
1126011003121	substrate interface [chemical binding]; other site
1126011003122	Flavin Reductases; Region: FlaRed; cl00801
1126011003123	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1126011003124	active site
1126011003125	catalytic residues [active]
1126011003126	metal binding site [ion binding]; metal-binding site
1126011003127	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1126011003128	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1126011003129	TPP-binding site [chemical binding]; other site
1126011003130	tetramer interface [polypeptide binding]; other site
1126011003131	heterodimer interface [polypeptide binding]; other site
1126011003132	phosphorylation loop region [posttranslational modification]
1126011003133	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1126011003134	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1126011003135	alpha subunit interface [polypeptide binding]; other site
1126011003136	TPP binding site [chemical binding]; other site
1126011003137	heterodimer interface [polypeptide binding]; other site
1126011003138	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011003139	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
1126011003140	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1126011003141	E3 interaction surface; other site
1126011003142	lipoyl attachment site [posttranslational modification]; other site
1126011003143	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1126011003144	E3 interaction surface; other site
1126011003145	lipoyl attachment site [posttranslational modification]; other site
1126011003146	e3 binding domain; Region: E3_binding; pfam02817
1126011003147	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1126011003148	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1126011003149	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1126011003150	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011003151	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1126011003152	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
1126011003153	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1126011003154	NAD(P) binding site [chemical binding]; other site
1126011003155	LDH/MDH dimer interface [polypeptide binding]; other site
1126011003156	substrate binding site [chemical binding]; other site
1126011003157	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4476
1126011003158	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1126011003159	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1126011003160	catalytic residues [active]
1126011003161	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1126011003162	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1126011003163	Cl binding site [ion binding]; other site
1126011003164	oligomer interface [polypeptide binding]; other site
1126011003165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
1126011003166	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
1126011003167	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1126011003168	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1126011003169	active site
1126011003170	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1126011003171	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1126011003172	G1 box; other site
1126011003173	putative GEF interaction site [polypeptide binding]; other site
1126011003174	GTP/Mg2+ binding site [chemical binding]; other site
1126011003175	Switch I region; other site
1126011003176	G2 box; other site
1126011003177	G3 box; other site
1126011003178	Switch II region; other site
1126011003179	G4 box; other site
1126011003180	G5 box; other site
1126011003181	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1126011003182	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1126011003183	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4896
1126011003184	hypothetical protein; Provisional; Region: PRK13666
1126011003185	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1126011003186	pyruvate carboxylase; Reviewed; Region: PRK12999
1126011003187	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1126011003188	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1126011003189	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1126011003190	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1126011003191	active site
1126011003192	catalytic residues [active]
1126011003193	metal binding site [ion binding]; metal-binding site
1126011003194	homodimer binding site [polypeptide binding]; other site
1126011003195	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1126011003196	carboxyltransferase (CT) interaction site; other site
1126011003197	biotinylation site [posttranslational modification]; other site
1126011003198	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
1126011003199	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1126011003200	putative binding site residues; other site
1126011003201	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1126011003202	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1126011003203	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1126011003204	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1126011003205	Walker A/P-loop; other site
1126011003206	ATP binding site [chemical binding]; other site
1126011003207	Q-loop/lid; other site
1126011003208	ABC transporter signature motif; other site
1126011003209	Walker B; other site
1126011003210	D-loop; other site
1126011003211	H-loop/switch region; other site
1126011003212	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011003213	SH3-like domain; Region: SH3_8; pfam13457
1126011003214	SH3-like domain; Region: SH3_8; pfam13457
1126011003215	SH3-like domain; Region: SH3_8; pfam13457
1126011003216	SH3-like domain; Region: SH3_8; pfam13457
1126011003217	SH3-like domain; Region: SH3_8; pfam13457
1126011003218	SH3-like domain; Region: SH3_8; pfam13457
1126011003219	SH3-like domain; Region: SH3_8; pfam13457
1126011003220	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1126011003221	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1126011003222	Ligand binding site; other site
1126011003223	Putative Catalytic site; other site
1126011003224	DXD motif; other site
1126011003225	conserved hypothetical integral membrane protein; Region: TIGR03766
1126011003226	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1126011003227	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1126011003228	active site
1126011003229	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1126011003230	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1126011003231	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1126011003232	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1126011003233	active site
1126011003234	tetramer interface; other site
1126011003235	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1126011003236	substrate binding site; other site
1126011003237	dimer interface; other site
1126011003238	ribitol-5-phosphate dehydrogenase; Region: ribitol-5-phosphate_DH; cd08237
1126011003239	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1126011003240	putative NAD(P) binding site [chemical binding]; other site
1126011003241	putative catalytic Zn binding site [ion binding]; other site
1126011003242	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1126011003243	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1126011003244	active site
1126011003245	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1126011003246	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1126011003247	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1126011003248	glycerol-3-phosphate cytidylyltransferase; Region: G3P_Cytidylyltransferase; cd02171
1126011003249	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1126011003250	active site
1126011003251	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1126011003252	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1126011003253	active site
1126011003254	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1126011003255	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1126011003256	homodimer interface [polypeptide binding]; other site
1126011003257	NAD binding pocket [chemical binding]; other site
1126011003258	ATP binding pocket [chemical binding]; other site
1126011003259	Mg binding site [ion binding]; other site
1126011003260	active-site loop [active]
1126011003261	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1126011003262	Phosphotransferase system cellobiose-specific component IIB [Carbohydrate transport and metabolism]; Region: CelA; COG1440
1126011003263	active site
1126011003264	P-loop; other site
1126011003265	phosphorylation site [posttranslational modification]
1126011003266	GMP synthase; Reviewed; Region: guaA; PRK00074
1126011003267	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1126011003268	AMP/PPi binding site [chemical binding]; other site
1126011003269	candidate oxyanion hole; other site
1126011003270	catalytic triad [active]
1126011003271	potential glutamine specificity residues [chemical binding]; other site
1126011003272	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1126011003273	ATP Binding subdomain [chemical binding]; other site
1126011003274	Dimerization subdomain; other site
1126011003275	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1126011003276	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011003277	active site
1126011003278	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1126011003279	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011003280	Walker A/P-loop; other site
1126011003281	ATP binding site [chemical binding]; other site
1126011003282	Q-loop/lid; other site
1126011003283	ABC transporter signature motif; other site
1126011003284	Walker B; other site
1126011003285	D-loop; other site
1126011003286	H-loop/switch region; other site
1126011003287	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
1126011003288	putative FMN binding site [chemical binding]; other site
1126011003289	NADPH bind site [chemical binding]; other site
1126011003290	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
1126011003291	YcaO-like family; Region: YcaO; pfam02624
1126011003292	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
1126011003293	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003294	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011003295	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003296	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1126011003297	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011003298	active site
1126011003299	Protein of unknown function (DUF3130; Region: DUF3130; cl12867
1126011003300	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1126011003301	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1126011003302	MepB protein; Region: MepB; cl01985
1126011003303	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1126011003304	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011003305	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011003306	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011003307	Coenzyme A binding pocket [chemical binding]; other site
1126011003308	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011003309	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1126011003310	DNA binding residues [nucleotide binding]
1126011003311	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1126011003312	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011003313	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011003314	Walker A/P-loop; other site
1126011003315	ATP binding site [chemical binding]; other site
1126011003316	Q-loop/lid; other site
1126011003317	ABC transporter signature motif; other site
1126011003318	Walker B; other site
1126011003319	D-loop; other site
1126011003320	H-loop/switch region; other site
1126011003321	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011003322	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011003323	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011003324	Walker A/P-loop; other site
1126011003325	ATP binding site [chemical binding]; other site
1126011003326	Q-loop/lid; other site
1126011003327	ABC transporter signature motif; other site
1126011003328	Walker B; other site
1126011003329	D-loop; other site
1126011003330	H-loop/switch region; other site
1126011003331	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1126011003332	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011003333	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011003334	DNA binding residues [nucleotide binding]
1126011003335	putative dimer interface [polypeptide binding]; other site
1126011003336	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1126011003337	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1126011003338	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
1126011003339	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011003340	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1126011003341	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011003342	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011003343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
1126011003344	Clp protease; Region: CLP_protease; pfam00574
1126011003345	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1126011003346	oligomer interface [polypeptide binding]; other site
1126011003347	active site residues [active]
1126011003348	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1126011003349	dimer interface [polypeptide binding]; other site
1126011003350	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011003351	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
1126011003352	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
1126011003353	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1126011003354	SLBB domain; Region: SLBB; pfam10531
1126011003355	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1126011003356	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1126011003357	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003358	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1126011003359	putative hexamer interface [polypeptide binding]; other site
1126011003360	putative hexagonal pore; other site
1126011003361	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1126011003362	putative hexamer interface [polypeptide binding]; other site
1126011003363	putative hexagonal pore; other site
1126011003364	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1126011003365	putative hexamer interface [polypeptide binding]; other site
1126011003366	putative hexagonal pore; other site
1126011003367	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1126011003368	G1 box; other site
1126011003369	GTP/Mg2+ binding site [chemical binding]; other site
1126011003370	G2 box; other site
1126011003371	Switch I region; other site
1126011003372	G3 box; other site
1126011003373	Switch II region; other site
1126011003374	G4 box; other site
1126011003375	G5 box; other site
1126011003376	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1126011003377	homotrimer interface [polypeptide binding]; other site
1126011003378	Walker A motif; other site
1126011003379	GTP binding site [chemical binding]; other site
1126011003380	Walker B motif; other site
1126011003381	Cobalamin-5-phosphate synthase [Coenzyme metabolism]; Region: CobS; COG0368
1126011003382	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011003383	catalytic core [active]
1126011003384	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1126011003385	Sensory domain found in PocR; Region: PocR; pfam10114
1126011003386	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003387	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011003388	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003389	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003390	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1126011003391	Hexamer interface [polypeptide binding]; other site
1126011003392	Hexagonal pore residue; other site
1126011003393	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
1126011003394	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1126011003395	putative hexamer interface [polypeptide binding]; other site
1126011003396	putative hexagonal pore; other site
1126011003397	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1126011003398	putative hexamer interface [polypeptide binding]; other site
1126011003399	putative hexagonal pore; other site
1126011003400	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1126011003401	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1126011003402	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1126011003403	alpha-beta subunit interface [polypeptide binding]; other site
1126011003404	alpha-gamma subunit interface [polypeptide binding]; other site
1126011003405	active site
1126011003406	substrate and K+ binding site; other site
1126011003407	K+ binding site [ion binding]; other site
1126011003408	cobalamin binding site [chemical binding]; other site
1126011003409	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1126011003410	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1126011003411	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1126011003412	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1126011003413	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003414	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1126011003415	putative hexamer interface [polypeptide binding]; other site
1126011003416	putative hexagonal pore; other site
1126011003417	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003418	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1126011003419	Hexamer interface [polypeptide binding]; other site
1126011003420	Hexagonal pore residue; other site
1126011003421	Propanediol utilization protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduL; COG4869
1126011003422	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1126011003423	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1126011003424	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1126011003425	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011003426	nucleotide binding site [chemical binding]; other site
1126011003427	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1126011003428	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1126011003429	Hexamer/Pentamer interface [polypeptide binding]; other site
1126011003430	central pore; other site
1126011003431	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1126011003432	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1126011003433	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1126011003434	putative catalytic cysteine [active]
1126011003435	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1126011003436	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1126011003437	putative active site [active]
1126011003438	metal binding site [ion binding]; metal-binding site
1126011003439	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1126011003440	amphipathic channel; other site
1126011003441	Asn-Pro-Ala signature motifs; other site
1126011003442	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1126011003443	propionate/acetate kinase; Provisional; Region: PRK12379
1126011003444	threonine-phosphate decarboxylase; Provisional; Region: PRK06358
1126011003445	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011003446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011003447	homodimer interface [polypeptide binding]; other site
1126011003448	catalytic residue [active]
1126011003449	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1126011003450	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1126011003451	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1126011003452	putative active site [active]
1126011003453	metal binding site [ion binding]; metal-binding site
1126011003454	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
1126011003455	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011003456	active site
1126011003457	phosphorylation site [posttranslational modification]
1126011003458	intermolecular recognition site; other site
1126011003459	dimerization interface [polypeptide binding]; other site
1126011003460	ANTAR domain; Region: ANTAR; pfam03861
1126011003461	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
1126011003462	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1126011003463	Histidine kinase; Region: HisKA_2; pfam07568
1126011003464	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011003465	ATP binding site [chemical binding]; other site
1126011003466	Mg2+ binding site [ion binding]; other site
1126011003467	G-X-G motif; other site
1126011003468	Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition [Amino acid transport and metabolism]; Region: EutA; COG4819
1126011003469	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1126011003470	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1126011003471	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1126011003472	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1126011003473	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1126011003474	putative hexamer interface [polypeptide binding]; other site
1126011003475	putative hexagonal pore; other site
1126011003476	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1126011003477	putative hexamer interface [polypeptide binding]; other site
1126011003478	putative hexagonal pore; other site
1126011003479	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003480	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1126011003481	Hexamer interface [polypeptide binding]; other site
1126011003482	Hexagonal pore residue; other site
1126011003483	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1126011003484	putative catalytic cysteine [active]
1126011003485	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1126011003486	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1126011003487	Hexamer interface [polypeptide binding]; other site
1126011003488	Putative hexagonal pore residue; other site
1126011003489	Ethanolamine utilization cobalamin adenosyltransferase [Amino acid transport and metabolism]; Region: EutT; COG4812
1126011003490	Propanediol utilization protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduL; COG4869
1126011003491	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1126011003492	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1126011003493	ethanolamine utilization protein; Region: eut_hyp; TIGR02536
1126011003494	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1126011003495	Hexamer/Pentamer interface [polypeptide binding]; other site
1126011003496	central pore; other site
1126011003497	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1126011003498	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1126011003499	putative hexamer interface [polypeptide binding]; other site
1126011003500	putative hexagonal pore; other site
1126011003501	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1126011003502	putative hexamer interface [polypeptide binding]; other site
1126011003503	putative hexagonal pore; other site
1126011003504	Ethanolamine utilisation protein, EutH; Region: EutH; pfam04346
1126011003505	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1126011003506	Ethanolamine utilisation protein EutQ; Region: EutQ; pfam06249
1126011003507	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003508	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011003509	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011003510	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
1126011003511	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1126011003512	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1126011003513	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1126011003514	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1126011003515	catalytic triad [active]
1126011003516	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1126011003517	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1126011003518	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1126011003519	Cobalamin biosynthesis protein CbiD [Coenzyme metabolism]; Region: CbiD; COG1903
1126011003520	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1126011003521	active site
1126011003522	putative homodimer interface [polypeptide binding]; other site
1126011003523	SAM binding site [chemical binding]; other site
1126011003524	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1126011003525	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011003526	S-adenosylmethionine binding site [chemical binding]; other site
1126011003527	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1126011003528	active site
1126011003529	SAM binding site [chemical binding]; other site
1126011003530	homodimer interface [polypeptide binding]; other site
1126011003531	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1126011003532	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1126011003533	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1126011003534	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1126011003535	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1126011003536	active site
1126011003537	SAM binding site [chemical binding]; other site
1126011003538	homodimer interface [polypeptide binding]; other site
1126011003539	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1126011003540	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1126011003541	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1126011003542	active site
1126011003543	SAM binding site [chemical binding]; other site
1126011003544	homodimer interface [polypeptide binding]; other site
1126011003545	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1126011003546	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1126011003547	active site
1126011003548	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1126011003549	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1126011003550	active site
1126011003551	C-terminal domain interface [polypeptide binding]; other site
1126011003552	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1126011003553	active site
1126011003554	N-terminal domain interface [polypeptide binding]; other site
1126011003555	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1126011003556	active site
1126011003557	SAM binding site [chemical binding]; other site
1126011003558	homodimer interface [polypeptide binding]; other site
1126011003559	cobalt transport protein CbiM; Validated; Region: PRK08319
1126011003560	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1126011003561	ABC-type cobalt transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CbiN; COG1930
1126011003562	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1126011003563	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1126011003564	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1126011003565	Walker A/P-loop; other site
1126011003566	ATP binding site [chemical binding]; other site
1126011003567	Q-loop/lid; other site
1126011003568	ABC transporter signature motif; other site
1126011003569	Walker B; other site
1126011003570	D-loop; other site
1126011003571	H-loop/switch region; other site
1126011003572	potential frameshift: common BLAST hit: gi|46907427|ref|YP_013816.1| cobyric acid synthase
1126011003573	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1126011003574	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1126011003575	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1126011003576	AAA domain; Region: AAA_17; cl17253
1126011003577	Predicted transcriptional regulators [Transcription]; Region: COG1695
1126011003578	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1126011003579	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
1126011003580	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011003581	SH3-like domain; Region: SH3_8; pfam13457
1126011003582	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011003583	SH3-like domain; Region: SH3_8; pfam13457
1126011003584	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1126011003585	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1126011003586	oligomer interface [polypeptide binding]; other site
1126011003587	active site
1126011003588	metal binding site [ion binding]; metal-binding site
1126011003589	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1126011003590	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1126011003591	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1126011003592	Predicted transcriptional regulators [Transcription]; Region: COG1733
1126011003593	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1126011003594	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1126011003595	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1126011003596	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1126011003597	dimer interface [polypeptide binding]; other site
1126011003598	motif 1; other site
1126011003599	active site
1126011003600	motif 2; other site
1126011003601	motif 3; other site
1126011003602	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1126011003603	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1126011003604	putative tRNA-binding site [nucleotide binding]; other site
1126011003605	B3/4 domain; Region: B3_4; pfam03483
1126011003606	tRNA synthetase B5 domain; Region: B5; smart00874
1126011003607	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1126011003608	dimer interface [polypeptide binding]; other site
1126011003609	motif 1; other site
1126011003610	motif 3; other site
1126011003611	motif 2; other site
1126011003612	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1126011003613	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011003614	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011003615	Walker A/P-loop; other site
1126011003616	ATP binding site [chemical binding]; other site
1126011003617	Q-loop/lid; other site
1126011003618	ABC transporter signature motif; other site
1126011003619	Walker B; other site
1126011003620	D-loop; other site
1126011003621	H-loop/switch region; other site
1126011003622	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011003623	FtsX-like permease family; Region: FtsX; pfam02687
1126011003624	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1126011003625	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011003626	FtsX-like permease family; Region: FtsX; pfam02687
1126011003627	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1126011003628	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011003629	putative DNA binding site [nucleotide binding]; other site
1126011003630	putative Zn2+ binding site [ion binding]; other site
1126011003631	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
1126011003632	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1126011003633	ligand binding site [chemical binding]; other site
1126011003634	active site
1126011003635	UGI interface [polypeptide binding]; other site
1126011003636	catalytic site [active]
1126011003637	ribonuclease HIII; Provisional; Region: PRK00996
1126011003638	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
1126011003639	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
1126011003640	RNA/DNA hybrid binding site [nucleotide binding]; other site
1126011003641	active site
1126011003642	Cell division protein ZapA; Region: ZapA; cl01146
1126011003643	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1126011003644	Colicin V production protein; Region: Colicin_V; pfam02674
1126011003645	hypothetical protein; Provisional; Region: PRK08609
1126011003646	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
1126011003647	active site
1126011003648	primer binding site [nucleotide binding]; other site
1126011003649	NTP  binding site [chemical binding]; other site
1126011003650	metal binding triad [ion binding]; metal-binding site
1126011003651	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
1126011003652	active site
1126011003653	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1126011003654	MutS domain III; Region: MutS_III; pfam05192
1126011003655	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011003656	Walker A/P-loop; other site
1126011003657	ATP binding site [chemical binding]; other site
1126011003658	Q-loop/lid; other site
1126011003659	ABC transporter signature motif; other site
1126011003660	Walker B; other site
1126011003661	D-loop; other site
1126011003662	H-loop/switch region; other site
1126011003663	Smr domain; Region: Smr; pfam01713
1126011003664	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011003665	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1126011003666	catalytic residues [active]
1126011003667	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1126011003668	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1126011003669	GIY-YIG motif/motif A; other site
1126011003670	active site
1126011003671	catalytic site [active]
1126011003672	putative DNA binding site [nucleotide binding]; other site
1126011003673	metal binding site [ion binding]; metal-binding site
1126011003674	UvrB/uvrC motif; Region: UVR; pfam02151
1126011003675	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1126011003676	aspartate kinase; Reviewed; Region: PRK06635
1126011003677	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1126011003678	putative nucleotide binding site [chemical binding]; other site
1126011003679	putative catalytic residues [active]
1126011003680	putative Mg ion binding site [ion binding]; other site
1126011003681	putative aspartate binding site [chemical binding]; other site
1126011003682	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1126011003683	putative allosteric regulatory site; other site
1126011003684	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923
1126011003685	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
1126011003686	Glutamate racemase [Cell envelope biogenesis, outer membrane]; Region: MurI; COG0796
1126011003687	ribonuclease PH; Reviewed; Region: rph; PRK00173
1126011003688	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1126011003689	hexamer interface [polypeptide binding]; other site
1126011003690	active site
1126011003691	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1126011003692	active site
1126011003693	dimerization interface [polypeptide binding]; other site
1126011003694	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1126011003695	active site
1126011003696	metal binding site [ion binding]; metal-binding site
1126011003697	homotetramer interface [polypeptide binding]; other site
1126011003698	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1126011003699	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011003700	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011003701	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011003702	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011003703	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011003704	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011003705	Uncharacterized conserved protein [Function unknown]; Region: COG5361
1126011003706	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
1126011003707	Protein of unknown function (DUF1214); Region: DUF1214; pfam06742
1126011003708	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
1126011003709	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1126011003710	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
1126011003711	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1126011003712	dimer interface [polypeptide binding]; other site
1126011003713	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011003714	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011003715	catalytic core [active]
1126011003716	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1126011003717	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1126011003718	ATP binding site [chemical binding]; other site
1126011003719	Mg++ binding site [ion binding]; other site
1126011003720	motif III; other site
1126011003721	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011003722	nucleotide binding region [chemical binding]; other site
1126011003723	ATP-binding site [chemical binding]; other site
1126011003724	RNA recognition motif in Bacillus subtilis ATP-dependent RNA helicase YxiN and similar proteins; Region: RRM_BsYxiN_like; cd12500
1126011003725	RNA binding site [nucleotide binding]; other site
1126011003726	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
1126011003727	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
1126011003728	putative active site [active]
1126011003729	nucleotide binding site [chemical binding]; other site
1126011003730	nudix motif; other site
1126011003731	putative metal binding site [ion binding]; other site
1126011003732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011003733	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011003734	putative substrate translocation pore; other site
1126011003735	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011003736	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011003737	ligand binding site [chemical binding]; other site
1126011003738	flexible hinge region; other site
1126011003739	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011003740	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1126011003741	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011003742	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011003743	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
1126011003744	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011003745	DNA-binding site [nucleotide binding]; DNA binding site
1126011003746	UTRA domain; Region: UTRA; pfam07702
1126011003747	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1126011003748	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1126011003749	Ca binding site [ion binding]; other site
1126011003750	active site
1126011003751	catalytic site [active]
1126011003752	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1126011003753	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
1126011003754	active site turn [active]
1126011003755	phosphorylation site [posttranslational modification]
1126011003756	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1126011003757	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_29; cd04688
1126011003758	nudix motif; other site
1126011003759	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1126011003760	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011003761	potential frameshift: common BLAST hit: gi|226223862|ref|YP_002757969.1| gamma-glutamyl phosphate reductase
1126011003762	Glutamate 5-kinase [Amino acid transport and metabolism]; Region: ProB; COG0263
1126011003763	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1126011003764	nucleotide binding site [chemical binding]; other site
1126011003765	homotetrameric interface [polypeptide binding]; other site
1126011003766	putative phosphate binding site [ion binding]; other site
1126011003767	putative allosteric binding site; other site
1126011003768	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
1126011003769	Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones]; Region: prsW; COG2339
1126011003770	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1126011003771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011003772	non-specific DNA binding site [nucleotide binding]; other site
1126011003773	salt bridge; other site
1126011003774	sequence-specific DNA binding site [nucleotide binding]; other site
1126011003775	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011003776	non-specific DNA binding site [nucleotide binding]; other site
1126011003777	salt bridge; other site
1126011003778	sequence-specific DNA binding site [nucleotide binding]; other site
1126011003779	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
1126011003780	active site
1126011003781	trigger factor; Provisional; Region: tig; PRK01490
1126011003782	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1126011003783	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1126011003784	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1126011003785	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1126011003786	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011003787	Walker A motif; other site
1126011003788	ATP binding site [chemical binding]; other site
1126011003789	Walker B motif; other site
1126011003790	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1126011003791	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1126011003792	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1126011003793	Catalytic site [active]
1126011003794	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1126011003795	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1126011003796	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1126011003797	Catalytic site [active]
1126011003798	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1126011003799	Signal peptidase, peptidase S26; Region: Peptidase_S26; pfam10502
1126011003800	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1126011003801	Catalytic site [active]
1126011003802	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1126011003803	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1126011003804	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1126011003805	GTP/Mg2+ binding site [chemical binding]; other site
1126011003806	G4 box; other site
1126011003807	G5 box; other site
1126011003808	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1126011003809	G1 box; other site
1126011003810	G1 box; other site
1126011003811	GTP/Mg2+ binding site [chemical binding]; other site
1126011003812	Switch I region; other site
1126011003813	G2 box; other site
1126011003814	G2 box; other site
1126011003815	G3 box; other site
1126011003816	G3 box; other site
1126011003817	Switch II region; other site
1126011003818	Switch II region; other site
1126011003819	G5 box; other site
1126011003820	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1126011003821	RNA/DNA hybrid binding site [nucleotide binding]; other site
1126011003822	active site
1126011003823	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1126011003824	DNA protecting protein DprA; Region: dprA; TIGR00732
1126011003825	DNA topoisomerase I; Validated; Region: PRK05582
1126011003826	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1126011003827	active site
1126011003828	interdomain interaction site; other site
1126011003829	putative metal-binding site [ion binding]; other site
1126011003830	nucleotide binding site [chemical binding]; other site
1126011003831	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1126011003832	domain I; other site
1126011003833	DNA binding groove [nucleotide binding]
1126011003834	phosphate binding site [ion binding]; other site
1126011003835	domain II; other site
1126011003836	domain III; other site
1126011003837	nucleotide binding site [chemical binding]; other site
1126011003838	catalytic site [active]
1126011003839	domain IV; other site
1126011003840	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1126011003841	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1126011003842	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1126011003843	Glucose inhibited division protein A; Region: GIDA; pfam01134
1126011003844	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1126011003845	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1126011003846	active site
1126011003847	DNA binding site [nucleotide binding]
1126011003848	Int/Topo IB signature motif; other site
1126011003849	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1126011003850	active site
1126011003851	HslU subunit interaction site [polypeptide binding]; other site
1126011003852	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1126011003853	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011003854	Walker A motif; other site
1126011003855	ATP binding site [chemical binding]; other site
1126011003856	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1126011003857	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1126011003858	transcriptional repressor CodY; Validated; Region: PRK04158
1126011003859	CodY GAF-like domain; Region: CodY; pfam06018
1126011003860	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
1126011003861	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1126011003862	active site
1126011003863	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
1126011003864	active site
1126011003865	catalytic residues [active]
1126011003866	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1126011003867	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1126011003868	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1126011003869	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011003870	Mg2+ binding site [ion binding]; other site
1126011003871	G-X-G motif; other site
1126011003872	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1126011003873	anchoring element; other site
1126011003874	dimer interface [polypeptide binding]; other site
1126011003875	ATP binding site [chemical binding]; other site
1126011003876	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1126011003877	active site
1126011003878	putative metal-binding site [ion binding]; other site
1126011003879	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1126011003880	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1126011003881	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1126011003882	CAP-like domain; other site
1126011003883	active site
1126011003884	primary dimer interface [polypeptide binding]; other site
1126011003885	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1126011003886	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1126011003887	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011003888	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1126011003889	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1126011003890	catalytic triad [active]
1126011003891	catalytic triad [active]
1126011003892	oxyanion hole [active]
1126011003893	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1126011003894	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
1126011003895	active site
1126011003896	catalytic site [active]
1126011003897	metal binding site [ion binding]; metal-binding site
1126011003898	dimer interface [polypeptide binding]; other site
1126011003899	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1126011003900	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1126011003901	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1126011003902	bacterial Hfq-like; Region: Hfq; cd01716
1126011003903	hexamer interface [polypeptide binding]; other site
1126011003904	Sm1 motif; other site
1126011003905	RNA binding site [nucleotide binding]; other site
1126011003906	Sm2 motif; other site
1126011003907	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1126011003908	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1126011003909	HflX GTPase family; Region: HflX; cd01878
1126011003910	G1 box; other site
1126011003911	GTP/Mg2+ binding site [chemical binding]; other site
1126011003912	Switch I region; other site
1126011003913	G2 box; other site
1126011003914	G3 box; other site
1126011003915	Switch II region; other site
1126011003916	G4 box; other site
1126011003917	G5 box; other site
1126011003918	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1126011003919	Aluminium resistance protein; Region: Alum_res; pfam06838
1126011003920	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1126011003921	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1126011003922	DNA binding residues [nucleotide binding]
1126011003923	putative dimer interface [polypeptide binding]; other site
1126011003924	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1126011003925	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1126011003926	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1126011003927	arsenical pump membrane protein; Provisional; Region: PRK15445
1126011003928	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1126011003929	transmembrane helices; other site
1126011003930	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1126011003931	LexA repressor; Validated; Region: PRK00215
1126011003932	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011003933	putative DNA binding site [nucleotide binding]; other site
1126011003934	putative Zn2+ binding site [ion binding]; other site
1126011003935	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1126011003936	Catalytic site [active]
1126011003937	cell division suppressor protein YneA; Provisional; Region: PRK14125
1126011003938	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1126011003939	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1126011003940	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1126011003941	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1126011003942	TPP-binding site [chemical binding]; other site
1126011003943	dimer interface [polypeptide binding]; other site
1126011003944	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1126011003945	PYR/PP interface [polypeptide binding]; other site
1126011003946	dimer interface [polypeptide binding]; other site
1126011003947	TPP binding site [chemical binding]; other site
1126011003948	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011003949	hypothetical protein; Provisional; Region: PRK01844
1126011003950	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1126011003951	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1126011003952	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011003953	S-adenosylmethionine binding site [chemical binding]; other site
1126011003954	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1126011003955	ParB-like nuclease domain; Region: ParBc; pfam02195
1126011003956	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1126011003957	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1126011003958	Active Sites [active]
1126011003959	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1126011003960	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1126011003961	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1126011003962	putative nucleotide binding site [chemical binding]; other site
1126011003963	uridine monophosphate binding site [chemical binding]; other site
1126011003964	homohexameric interface [polypeptide binding]; other site
1126011003965	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1126011003966	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1126011003967	hinge region; other site
1126011003968	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
1126011003969	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1126011003970	catalytic residue [active]
1126011003971	putative FPP diphosphate  binding site; other site
1126011003972	putative FPP binding hydrophobic cleft; other site
1126011003973	dimer interface [polypeptide binding]; other site
1126011003974	putative IPP diphosphate binding site; other site
1126011003975	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1126011003976	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1126011003977	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
1126011003978	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1126011003979	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1126011003980	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1126011003981	RIP metalloprotease RseP; Region: TIGR00054
1126011003982	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1126011003983	active site
1126011003984	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1126011003985	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1126011003986	protein binding site [polypeptide binding]; other site
1126011003987	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1126011003988	putative substrate binding region [chemical binding]; other site
1126011003989	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1126011003990	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1126011003991	dimer interface [polypeptide binding]; other site
1126011003992	motif 1; other site
1126011003993	active site
1126011003994	motif 2; other site
1126011003995	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1126011003996	putative deacylase active site [active]
1126011003997	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1126011003998	active site
1126011003999	motif 3; other site
1126011004000	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1126011004001	anticodon binding site; other site
1126011004002	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1126011004003	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
1126011004004	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1126011004005	generic binding surface II; other site
1126011004006	generic binding surface I; other site
1126011004007	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1126011004008	active site
1126011004009	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1126011004010	active site
1126011004011	catalytic site [active]
1126011004012	substrate binding site [chemical binding]; other site
1126011004013	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1126011004014	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1126011004015	Sm and related proteins; Region: Sm_like; cl00259
1126011004016	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1126011004017	putative oligomer interface [polypeptide binding]; other site
1126011004018	putative RNA binding site [nucleotide binding]; other site
1126011004019	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1126011004020	NusA N-terminal domain; Region: NusA_N; pfam08529
1126011004021	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1126011004022	RNA binding site [nucleotide binding]; other site
1126011004023	homodimer interface [polypeptide binding]; other site
1126011004024	NusA-like KH domain; Region: KH_5; pfam13184
1126011004025	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1126011004026	G-X-X-G motif; other site
1126011004027	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1126011004028	putative RNA binding cleft [nucleotide binding]; other site
1126011004029	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
1126011004030	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1126011004031	translation initiation factor IF-2; Region: IF-2; TIGR00487
1126011004032	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1126011004033	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1126011004034	G1 box; other site
1126011004035	putative GEF interaction site [polypeptide binding]; other site
1126011004036	GTP/Mg2+ binding site [chemical binding]; other site
1126011004037	Switch I region; other site
1126011004038	G2 box; other site
1126011004039	G3 box; other site
1126011004040	Switch II region; other site
1126011004041	G4 box; other site
1126011004042	G5 box; other site
1126011004043	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1126011004044	Translation-initiation factor 2; Region: IF-2; pfam11987
1126011004045	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1126011004046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1550
1126011004047	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1126011004048	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
1126011004049	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1126011004050	RNA binding site [nucleotide binding]; other site
1126011004051	active site
1126011004052	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1126011004053	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1126011004054	active site
1126011004055	Riboflavin kinase; Region: Flavokinase; smart00904
1126011004056	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1126011004057	16S/18S rRNA binding site [nucleotide binding]; other site
1126011004058	S13e-L30e interaction site [polypeptide binding]; other site
1126011004059	25S rRNA binding site [nucleotide binding]; other site
1126011004060	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1126011004061	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1126011004062	RNase E interface [polypeptide binding]; other site
1126011004063	trimer interface [polypeptide binding]; other site
1126011004064	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1126011004065	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1126011004066	RNase E interface [polypeptide binding]; other site
1126011004067	trimer interface [polypeptide binding]; other site
1126011004068	active site
1126011004069	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1126011004070	putative nucleic acid binding region [nucleotide binding]; other site
1126011004071	G-X-X-G motif; other site
1126011004072	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1126011004073	RNA binding site [nucleotide binding]; other site
1126011004074	domain interface; other site
1126011004075	GTPase RsgA; Reviewed; Region: PRK01889
1126011004076	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1126011004077	RNA binding site [nucleotide binding]; other site
1126011004078	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1126011004079	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1126011004080	GTP/Mg2+ binding site [chemical binding]; other site
1126011004081	G4 box; other site
1126011004082	G5 box; other site
1126011004083	G1 box; other site
1126011004084	Switch I region; other site
1126011004085	G2 box; other site
1126011004086	G3 box; other site
1126011004087	Switch II region; other site
1126011004088	YceG-like family; Region: YceG; pfam02618
1126011004089	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1126011004090	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
1126011004091	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1126011004092	Rhomboid family; Region: Rhomboid; pfam01694
1126011004093	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011004094	TPR motif; other site
1126011004095	TPR repeat; Region: TPR_11; pfam13414
1126011004096	binding surface
1126011004097	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4483
1126011004098	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1126011004099	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011004100	nucleotide binding site [chemical binding]; other site
1126011004101	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1126011004102	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1126011004103	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
1126011004104	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1126011004105	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1126011004106	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1126011004107	Type II/IV secretion system protein; Region: T2SE; pfam00437
1126011004108	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1126011004109	Walker A motif; other site
1126011004110	ATP binding site [chemical binding]; other site
1126011004111	Walker B motif; other site
1126011004112	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1126011004113	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
1126011004114	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1126011004115	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1126011004116	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1126011004117	tetramer interface [polypeptide binding]; other site
1126011004118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011004119	catalytic residue [active]
1126011004120	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1126011004121	tetramer interface [polypeptide binding]; other site
1126011004122	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011004123	catalytic residue [active]
1126011004124	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1126011004125	active site residue [active]
1126011004126	Predicted metal-dependent enzyme [General function prediction only]; Region: COG3872
1126011004127	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1126011004128	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1126011004129	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1126011004130	active site
1126011004131	elongation factor P; Validated; Region: PRK00529
1126011004132	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1126011004133	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1126011004134	RNA binding site [nucleotide binding]; other site
1126011004135	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1126011004136	RNA binding site [nucleotide binding]; other site
1126011004137	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1126011004138	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1126011004139	carboxyltransferase (CT) interaction site; other site
1126011004140	biotinylation site [posttranslational modification]; other site
1126011004141	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1126011004142	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1126011004143	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1126011004144	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1126011004145	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1126011004146	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1126011004147	putative RNA binding site [nucleotide binding]; other site
1126011004148	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14170
1126011004149	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1126011004150	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1126011004151	homodimer interface [polypeptide binding]; other site
1126011004152	NADP binding site [chemical binding]; other site
1126011004153	substrate binding site [chemical binding]; other site
1126011004154	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1126011004155	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1126011004156	generic binding surface II; other site
1126011004157	generic binding surface I; other site
1126011004158	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14064
1126011004159	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1126011004160	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1126011004161	substrate binding pocket [chemical binding]; other site
1126011004162	chain length determination region; other site
1126011004163	substrate-Mg2+ binding site; other site
1126011004164	catalytic residues [active]
1126011004165	aspartate-rich region 1; other site
1126011004166	active site lid residues [active]
1126011004167	aspartate-rich region 2; other site
1126011004168	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1126011004169	DNA-binding site [nucleotide binding]; DNA binding site
1126011004170	RNA-binding motif; other site
1126011004171	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1126011004172	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1126011004173	TPP-binding site; other site
1126011004174	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1126011004175	PYR/PP interface [polypeptide binding]; other site
1126011004176	dimer interface [polypeptide binding]; other site
1126011004177	TPP binding site [chemical binding]; other site
1126011004178	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011004179	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1126011004180	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011004181	RNA binding surface [nucleotide binding]; other site
1126011004182	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1126011004183	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1126011004184	arginine repressor; Provisional; Region: PRK04280
1126011004185	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1126011004186	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1126011004187	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1126011004188	Walker A/P-loop; other site
1126011004189	ATP binding site [chemical binding]; other site
1126011004190	Q-loop/lid; other site
1126011004191	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1126011004192	ABC transporter signature motif; other site
1126011004193	Walker B; other site
1126011004194	D-loop; other site
1126011004195	H-loop/switch region; other site
1126011004196	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
1126011004197	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011004198	nucleotide binding site [chemical binding]; other site
1126011004199	Acetokinase family; Region: Acetate_kinase; cl17229
1126011004200	dihydrolipoamide dehydrogenase; Validated; Region: PRK05976
1126011004201	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011004202	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1126011004203	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
1126011004204	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1126011004205	tetramer interface [polypeptide binding]; other site
1126011004206	TPP-binding site [chemical binding]; other site
1126011004207	heterodimer interface [polypeptide binding]; other site
1126011004208	phosphorylation loop region [posttranslational modification]
1126011004209	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1126011004210	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1126011004211	alpha subunit interface [polypeptide binding]; other site
1126011004212	TPP binding site [chemical binding]; other site
1126011004213	heterodimer interface [polypeptide binding]; other site
1126011004214	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1126011004215	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1126011004216	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1126011004217	E3 interaction surface; other site
1126011004218	lipoyl attachment site [posttranslational modification]; other site
1126011004219	e3 binding domain; Region: E3_binding; pfam02817
1126011004220	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1126011004221	peptidase T-like protein; Region: PepT-like; TIGR01883
1126011004222	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1126011004223	metal binding site [ion binding]; metal-binding site
1126011004224	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1126011004225	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1126011004226	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1126011004227	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011004228	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011004229	active site
1126011004230	phosphorylation site [posttranslational modification]
1126011004231	intermolecular recognition site; other site
1126011004232	dimerization interface [polypeptide binding]; other site
1126011004233	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011004234	DNA binding site [nucleotide binding]
1126011004235	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1126011004236	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011004237	dimerization interface [polypeptide binding]; other site
1126011004238	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011004239	dimer interface [polypeptide binding]; other site
1126011004240	phosphorylation site [posttranslational modification]
1126011004241	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011004242	ATP binding site [chemical binding]; other site
1126011004243	Mg2+ binding site [ion binding]; other site
1126011004244	G-X-G motif; other site
1126011004245	OxaA-like protein precursor; Validated; Region: PRK01622
1126011004246	acylphosphatase; Provisional; Region: PRK14443
1126011004247	Protein of unknown function (DUF1033); Region: DUF1033; cl11549
1126011004248	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1126011004249	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1126011004250	homotetramer interface [polypeptide binding]; other site
1126011004251	FMN binding site [chemical binding]; other site
1126011004252	homodimer contacts [polypeptide binding]; other site
1126011004253	putative active site [active]
1126011004254	putative substrate binding site [chemical binding]; other site
1126011004255	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1126011004256	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1126011004257	active site residue [active]
1126011004258	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
1126011004259	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1126011004260	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011004261	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011004262	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1126011004263	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1126011004264	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1126011004265	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1126011004266	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06928
1126011004267	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1126011004268	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1126011004269	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1126011004270	ligand binding site [chemical binding]; other site
1126011004271	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
1126011004272	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1126011004273	Walker A/P-loop; other site
1126011004274	ATP binding site [chemical binding]; other site
1126011004275	Q-loop/lid; other site
1126011004276	ABC transporter signature motif; other site
1126011004277	Walker B; other site
1126011004278	D-loop; other site
1126011004279	H-loop/switch region; other site
1126011004280	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1126011004281	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1126011004282	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1126011004283	TM-ABC transporter signature motif; other site
1126011004284	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1126011004285	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1126011004286	TM-ABC transporter signature motif; other site
1126011004287	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1126011004288	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1126011004289	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1126011004290	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1126011004291	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1126011004292	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1126011004293	classical (c) SDRs; Region: SDR_c; cd05233
1126011004294	NAD(P) binding site [chemical binding]; other site
1126011004295	active site
1126011004296	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1126011004297	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011004298	non-specific DNA binding site [nucleotide binding]; other site
1126011004299	salt bridge; other site
1126011004300	sequence-specific DNA binding site [nucleotide binding]; other site
1126011004301	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1126011004302	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1126011004303	competence damage-inducible protein A; Provisional; Region: PRK00549
1126011004304	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1126011004305	putative MPT binding site; other site
1126011004306	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
1126011004307	recombinase A; Provisional; Region: recA; PRK09354
1126011004308	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1126011004309	hexamer interface [polypeptide binding]; other site
1126011004310	Walker A motif; other site
1126011004311	ATP binding site [chemical binding]; other site
1126011004312	Walker B motif; other site
1126011004313	phosphodiesterase; Provisional; Region: PRK12704
1126011004314	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011004315	Zn2+ binding site [ion binding]; other site
1126011004316	Mg2+ binding site [ion binding]; other site
1126011004317	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1126011004318	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011004319	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1126011004320	Coenzyme A binding pocket [chemical binding]; other site
1126011004321	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
1126011004322	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1126011004323	putative active site [active]
1126011004324	metal binding site [ion binding]; metal-binding site
1126011004325	homodimer binding site [polypeptide binding]; other site
1126011004326	Predicted membrane protein [Function unknown]; Region: COG4550
1126011004327	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1126011004328	MutS domain I; Region: MutS_I; pfam01624
1126011004329	MutS domain II; Region: MutS_II; pfam05188
1126011004330	MutS domain III; Region: MutS_III; pfam05192
1126011004331	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1126011004332	Walker A/P-loop; other site
1126011004333	ATP binding site [chemical binding]; other site
1126011004334	Q-loop/lid; other site
1126011004335	ABC transporter signature motif; other site
1126011004336	Walker B; other site
1126011004337	D-loop; other site
1126011004338	H-loop/switch region; other site
1126011004339	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1126011004340	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011004341	ATP binding site [chemical binding]; other site
1126011004342	Mg2+ binding site [ion binding]; other site
1126011004343	G-X-G motif; other site
1126011004344	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1126011004345	ATP binding site [chemical binding]; other site
1126011004346	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1126011004347	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1126011004348	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1126011004349	Pyruvate formate lyase 1; Region: PFL1; cd01678
1126011004350	coenzyme A binding site [chemical binding]; other site
1126011004351	active site
1126011004352	catalytic residues [active]
1126011004353	glycine loop; other site
1126011004354	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
1126011004355	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1126011004356	FeS/SAM binding site; other site
1126011004357	Predicted transcriptional regulators [Transcription]; Region: COG1695
1126011004358	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1126011004359	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011004360	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011004361	putative substrate translocation pore; other site
1126011004362	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1126011004363	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011004364	non-specific DNA binding site [nucleotide binding]; other site
1126011004365	salt bridge; other site
1126011004366	sequence-specific DNA binding site [nucleotide binding]; other site
1126011004367	topology modulation protein; Reviewed; Region: PRK08118
1126011004368	AAA domain; Region: AAA_17; pfam13207
1126011004369	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011004370	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011004371	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011004372	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011004373	putative acyltransferase; Provisional; Region: PRK05790
1126011004374	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1126011004375	dimer interface [polypeptide binding]; other site
1126011004376	active site
1126011004377	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1126011004378	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
1126011004379	dimer interface [polypeptide binding]; other site
1126011004380	active site
1126011004381	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
1126011004382	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
1126011004383	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011004384	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1126011004385	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1126011004386	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1126011004387	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1126011004388	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1126011004389	FAD binding domain; Region: FAD_binding_4; pfam01565
1126011004390	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1126011004391	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1126011004392	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1126011004393	Walker A/P-loop; other site
1126011004394	ATP binding site [chemical binding]; other site
1126011004395	Q-loop/lid; other site
1126011004396	ABC transporter signature motif; other site
1126011004397	Walker B; other site
1126011004398	D-loop; other site
1126011004399	H-loop/switch region; other site
1126011004400	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011004401	dimer interface [polypeptide binding]; other site
1126011004402	conserved gate region; other site
1126011004403	ABC-ATPase subunit interface; other site
1126011004404	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1126011004405	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1126011004406	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1126011004407	manganese transport protein MntH; Reviewed; Region: PRK00701
1126011004408	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1126011004409	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011004410	dimer interface [polypeptide binding]; other site
1126011004411	conserved gate region; other site
1126011004412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1126011004413	ABC-ATPase subunit interface; other site
1126011004414	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1126011004415	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1126011004416	dimerization interface [polypeptide binding]; other site
1126011004417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011004418	dimer interface [polypeptide binding]; other site
1126011004419	conserved gate region; other site
1126011004420	putative PBP binding loops; other site
1126011004421	ABC-ATPase subunit interface; other site
1126011004422	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1126011004423	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
1126011004424	Walker A/P-loop; other site
1126011004425	ATP binding site [chemical binding]; other site
1126011004426	Q-loop/lid; other site
1126011004427	ABC transporter signature motif; other site
1126011004428	Walker B; other site
1126011004429	D-loop; other site
1126011004430	H-loop/switch region; other site
1126011004431	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1126011004432	Predicted membrane protein [Function unknown]; Region: COG3859
1126011004433	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1126011004434	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1126011004435	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011004436	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011004437	ABC transporter; Region: ABC_tran_2; pfam12848
1126011004438	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011004439	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
1126011004440	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011004441	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011004442	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1126011004443	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1126011004444	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011004445	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1126011004446	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1126011004447	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1126011004448	dimer interface [polypeptide binding]; other site
1126011004449	active site
1126011004450	catalytic residue [active]
1126011004451	aspartate kinase I; Reviewed; Region: PRK08210
1126011004452	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1126011004453	nucleotide binding site [chemical binding]; other site
1126011004454	substrate binding site [chemical binding]; other site
1126011004455	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_1; cd04914
1126011004456	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_2; cd04937
1126011004457	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1126011004458	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1126011004459	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1126011004460	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1126011004461	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1126011004462	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1126011004463	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1126011004464	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1126011004465	Protein of unknown function (DUF1189); Region: DUF1189; pfam06691
1126011004466	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1126011004467	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1126011004468	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1126011004469	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1126011004470	Predicted membrane protein [Function unknown]; Region: COG4392
1126011004471	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1126011004472	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1126011004473	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1126011004474	metal binding site 2 [ion binding]; metal-binding site
1126011004475	putative DNA binding helix; other site
1126011004476	metal binding site 1 [ion binding]; metal-binding site
1126011004477	dimer interface [polypeptide binding]; other site
1126011004478	structural Zn2+ binding site [ion binding]; other site
1126011004479	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1126011004480	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011004481	ABC-ATPase subunit  interface; other site
1126011004482	dimer interface [polypeptide binding]; other site
1126011004483	putative PBP binding regions; other site
1126011004484	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1126011004485	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1126011004486	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1126011004487	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1126011004488	DHHA2 domain; Region: DHHA2; pfam02833
1126011004489	endonuclease IV; Provisional; Region: PRK01060
1126011004490	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1126011004491	AP (apurinic/apyrimidinic) site pocket; other site
1126011004492	DNA interaction; other site
1126011004493	Metal-binding active site; metal-binding site
1126011004494	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1126011004495	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1126011004496	ATP binding site [chemical binding]; other site
1126011004497	Mg++ binding site [ion binding]; other site
1126011004498	motif III; other site
1126011004499	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011004500	nucleotide binding region [chemical binding]; other site
1126011004501	ATP-binding site [chemical binding]; other site
1126011004502	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1126011004503	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1126011004504	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1126011004505	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1126011004506	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1126011004507	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1126011004508	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1126011004509	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1126011004510	Family of unknown function (DUF633); Region: DUF633; pfam04816
1126011004511	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1126011004512	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1126011004513	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1126011004514	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1126011004515	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1126011004516	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1126011004517	DNA binding residues [nucleotide binding]
1126011004518	DNA primase; Validated; Region: dnaG; PRK05667
1126011004519	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1126011004520	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1126011004521	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1126011004522	active site
1126011004523	metal binding site [ion binding]; metal-binding site
1126011004524	interdomain interaction site; other site
1126011004525	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1126011004526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1671
1126011004527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
1126011004528	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1126011004529	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1126011004530	DALR anticodon binding domain; Region: DALR_1; pfam05746
1126011004531	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1126011004532	dimer interface [polypeptide binding]; other site
1126011004533	motif 1; other site
1126011004534	active site
1126011004535	motif 2; other site
1126011004536	motif 3; other site
1126011004537	DNA repair protein RecO; Region: reco; TIGR00613
1126011004538	Recombination protein O N terminal; Region: RecO_N; pfam11967
1126011004539	Recombination protein O C terminal; Region: RecO_C; pfam02565
1126011004540	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
1126011004541	GTPase Era; Reviewed; Region: era; PRK00089
1126011004542	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1126011004543	G1 box; other site
1126011004544	GTP/Mg2+ binding site [chemical binding]; other site
1126011004545	Switch I region; other site
1126011004546	G2 box; other site
1126011004547	Switch II region; other site
1126011004548	G3 box; other site
1126011004549	G4 box; other site
1126011004550	G5 box; other site
1126011004551	KH domain; Region: KH_2; pfam07650
1126011004552	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1126011004553	active site
1126011004554	catalytic motif [active]
1126011004555	Zn binding site [ion binding]; other site
1126011004556	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1126011004557	metal-binding heat shock protein; Provisional; Region: PRK00016
1126011004558	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1126011004559	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1126011004560	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011004561	Zn2+ binding site [ion binding]; other site
1126011004562	Mg2+ binding site [ion binding]; other site
1126011004563	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1126011004564	PhoH-like protein; Region: PhoH; pfam02562
1126011004565	Yqey-like protein; Region: YqeY; pfam09424
1126011004566	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1126011004567	RNA methyltransferase, RsmE family; Region: TIGR00046
1126011004568	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1126011004569	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1126011004570	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011004571	S-adenosylmethionine binding site [chemical binding]; other site
1126011004572	chaperone protein DnaJ; Provisional; Region: PRK14280
1126011004573	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1126011004574	HSP70 interaction site [polypeptide binding]; other site
1126011004575	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1126011004576	substrate binding site [polypeptide binding]; other site
1126011004577	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1126011004578	Zn binding sites [ion binding]; other site
1126011004579	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1126011004580	dimer interface [polypeptide binding]; other site
1126011004581	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1126011004582	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1126011004583	nucleotide binding site [chemical binding]; other site
1126011004584	NEF interaction site [polypeptide binding]; other site
1126011004585	SBD interface [polypeptide binding]; other site
1126011004586	heat shock protein GrpE; Provisional; Region: PRK14140
1126011004587	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1126011004588	dimer interface [polypeptide binding]; other site
1126011004589	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1126011004590	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1126011004591	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1126011004592	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1126011004593	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1126011004594	FeS/SAM binding site; other site
1126011004595	HemN C-terminal domain; Region: HemN_C; pfam06969
1126011004596	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1126011004597	aldehyde reductase, extended (e) SDRs; Region: AR_SDR_e; cd05227
1126011004598	NADP binding site [chemical binding]; other site
1126011004599	putative substrate binding site [chemical binding]; other site
1126011004600	active site
1126011004601	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011004602	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011004603	DNA binding residues [nucleotide binding]
1126011004604	putative dimer interface [polypeptide binding]; other site
1126011004605	GTP-binding protein LepA; Provisional; Region: PRK05433
1126011004606	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1126011004607	G1 box; other site
1126011004608	putative GEF interaction site [polypeptide binding]; other site
1126011004609	GTP/Mg2+ binding site [chemical binding]; other site
1126011004610	Switch I region; other site
1126011004611	G2 box; other site
1126011004612	G3 box; other site
1126011004613	Switch II region; other site
1126011004614	G4 box; other site
1126011004615	G5 box; other site
1126011004616	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1126011004617	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1126011004618	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1126011004619	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1126011004620	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1126011004621	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1126011004622	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1126011004623	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
1126011004624	Competence protein; Region: Competence; pfam03772
1126011004625	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011004626	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1126011004627	catalytic motif [active]
1126011004628	Zn binding site [ion binding]; other site
1126011004629	SLBB domain; Region: SLBB; pfam10531
1126011004630	comEA protein; Region: comE; TIGR01259
1126011004631	Helix-hairpin-helix motif; Region: HHH; pfam00633
1126011004632	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1126011004633	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011004634	S-adenosylmethionine binding site [chemical binding]; other site
1126011004635	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1126011004636	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011004637	Zn2+ binding site [ion binding]; other site
1126011004638	Mg2+ binding site [ion binding]; other site
1126011004639	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1126011004640	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1126011004641	active site
1126011004642	(T/H)XGH motif; other site
1126011004643	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1126011004644	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1126011004645	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1126011004646	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1126011004647	shikimate binding site; other site
1126011004648	NAD(P) binding site [chemical binding]; other site
1126011004649	GTPase YqeH; Provisional; Region: PRK13796
1126011004650	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
1126011004651	GTP/Mg2+ binding site [chemical binding]; other site
1126011004652	G4 box; other site
1126011004653	G5 box; other site
1126011004654	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1126011004655	G1 box; other site
1126011004656	G1 box; other site
1126011004657	GTP/Mg2+ binding site [chemical binding]; other site
1126011004658	G2 box; other site
1126011004659	Switch I region; other site
1126011004660	G2 box; other site
1126011004661	Switch I region; other site
1126011004662	G3 box; other site
1126011004663	G3 box; other site
1126011004664	Switch II region; other site
1126011004665	Switch II region; other site
1126011004666	G4 box; other site
1126011004667	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
1126011004668	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011004669	motif II; other site
1126011004670	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1126011004671	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
1126011004672	active site
1126011004673	Zn binding site [ion binding]; other site
1126011004674	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1126011004675	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1126011004676	Protein of unknown function (DUF1510); Region: DUF1510; pfam07423
1126011004677	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1126011004678	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1126011004679	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1126011004680	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1126011004681	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1126011004682	Sugar specificity; other site
1126011004683	Pyrimidine base specificity; other site
1126011004684	ATP-binding site [chemical binding]; other site
1126011004685	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1126011004686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011004687	S-adenosylmethionine binding site [chemical binding]; other site
1126011004688	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1126011004689	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1126011004690	dimerization interface [polypeptide binding]; other site
1126011004691	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1126011004692	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1126011004693	hypothetical protein; Provisional; Region: PRK13678
1126011004694	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1126011004695	hypothetical protein; Provisional; Region: PRK05473
1126011004696	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1126011004697	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1126011004698	motif 1; other site
1126011004699	active site
1126011004700	motif 2; other site
1126011004701	motif 3; other site
1126011004702	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1126011004703	DHHA1 domain; Region: DHHA1; pfam02272
1126011004704	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011004705	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011004706	Walker A/P-loop; other site
1126011004707	ATP binding site [chemical binding]; other site
1126011004708	Q-loop/lid; other site
1126011004709	ABC transporter signature motif; other site
1126011004710	Walker B; other site
1126011004711	D-loop; other site
1126011004712	H-loop/switch region; other site
1126011004713	potential frameshift: common BLAST hit: gi|226224107|ref|YP_002758214.1| transporter
1126011004714	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011004715	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011004716	active site
1126011004717	phosphorylation site [posttranslational modification]
1126011004718	intermolecular recognition site; other site
1126011004719	dimerization interface [polypeptide binding]; other site
1126011004720	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011004721	DNA binding site [nucleotide binding]
1126011004722	sensor kinase CusS; Provisional; Region: PRK09835
1126011004723	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011004724	dimerization interface [polypeptide binding]; other site
1126011004725	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011004726	dimer interface [polypeptide binding]; other site
1126011004727	phosphorylation site [posttranslational modification]
1126011004728	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011004729	ATP binding site [chemical binding]; other site
1126011004730	Mg2+ binding site [ion binding]; other site
1126011004731	G-X-G motif; other site
1126011004732	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1126011004733	AAA domain; Region: AAA_30; pfam13604
1126011004734	Family description; Region: UvrD_C_2; pfam13538
1126011004735	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011004736	binding surface
1126011004737	TPR motif; other site
1126011004738	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1126011004739	TPR repeat; Region: TPR_11; pfam13414
1126011004740	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011004741	binding surface
1126011004742	TPR motif; other site
1126011004743	TPR repeat; Region: TPR_11; pfam13414
1126011004744	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1126011004745	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1126011004746	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1126011004747	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1126011004748	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1126011004749	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011004750	catalytic residue [active]
1126011004751	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
1126011004752	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011004753	Walker A motif; other site
1126011004754	ATP binding site [chemical binding]; other site
1126011004755	Walker B motif; other site
1126011004756	arginine finger; other site
1126011004757	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1126011004758	Predicted transcriptional regulator [Transcription]; Region: COG1959
1126011004759	Transcriptional regulator; Region: Rrf2; pfam02082
1126011004760	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1126011004761	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
1126011004762	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1126011004763	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1126011004764	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1126011004765	dimer interface [polypeptide binding]; other site
1126011004766	anticodon binding site; other site
1126011004767	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1126011004768	homodimer interface [polypeptide binding]; other site
1126011004769	motif 1; other site
1126011004770	active site
1126011004771	motif 2; other site
1126011004772	GAD domain; Region: GAD; pfam02938
1126011004773	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1126011004774	motif 3; other site
1126011004775	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1126011004776	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1126011004777	dimer interface [polypeptide binding]; other site
1126011004778	motif 1; other site
1126011004779	active site
1126011004780	motif 2; other site
1126011004781	motif 3; other site
1126011004782	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1126011004783	anticodon binding site; other site
1126011004784	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
1126011004785	Bacterial SH3 domain; Region: SH3_3; pfam08239
1126011004786	Bacterial SH3 domain; Region: SH3_3; pfam08239
1126011004787	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1126011004788	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1126011004789	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1126011004790	active site
1126011004791	metal binding site [ion binding]; metal-binding site
1126011004792	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1126011004793	putative active site [active]
1126011004794	dimerization interface [polypeptide binding]; other site
1126011004795	putative tRNAtyr binding site [nucleotide binding]; other site
1126011004796	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1126011004797	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011004798	Zn2+ binding site [ion binding]; other site
1126011004799	Mg2+ binding site [ion binding]; other site
1126011004800	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1126011004801	synthetase active site [active]
1126011004802	NTP binding site [chemical binding]; other site
1126011004803	metal binding site [ion binding]; metal-binding site
1126011004804	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1126011004805	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1126011004806	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011004807	active site
1126011004808	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1126011004809	DHH family; Region: DHH; pfam01368
1126011004810	DHHA1 domain; Region: DHHA1; pfam02272
1126011004811	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4199
1126011004812	Uncharacterized integral membrane protein [Function unknown]; Region: COG5416
1126011004813	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
1126011004814	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1126011004815	Protein export membrane protein; Region: SecD_SecF; cl14618
1126011004816	Protein export membrane protein; Region: SecD_SecF; pfam02355
1126011004817	Post-transcriptional regulator; Region: Post_transc_reg; pfam13797
1126011004818	Preprotein translocase subunit; Region: YajC; pfam02699
1126011004819	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1126011004820	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1126011004821	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1126011004822	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1126011004823	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1126011004824	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011004825	Walker A motif; other site
1126011004826	ATP binding site [chemical binding]; other site
1126011004827	Walker B motif; other site
1126011004828	arginine finger; other site
1126011004829	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1126011004830	Holliday junction resolvasome, DNA-binding subunit [DNA replication, recombination, and repair]; Region: RuvA; COG0632
1126011004831	RuvA N terminal domain; Region: RuvA_N; pfam01330
1126011004832	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1126011004833	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1126011004834	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011004835	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1126011004836	NAD binding site [chemical binding]; other site
1126011004837	dimer interface [polypeptide binding]; other site
1126011004838	substrate binding site [chemical binding]; other site
1126011004839	hypothetical protein; Validated; Region: PRK00110
1126011004840	prephenate dehydratase; Provisional; Region: PRK11898
1126011004841	Prephenate dehydratase; Region: PDT; pfam00800
1126011004842	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1126011004843	putative L-Phe binding site [chemical binding]; other site
1126011004844	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1126011004845	GTP1/OBG; Region: GTP1_OBG; pfam01018
1126011004846	Obg GTPase; Region: Obg; cd01898
1126011004847	G1 box; other site
1126011004848	GTP/Mg2+ binding site [chemical binding]; other site
1126011004849	Switch I region; other site
1126011004850	G2 box; other site
1126011004851	G3 box; other site
1126011004852	Switch II region; other site
1126011004853	G4 box; other site
1126011004854	G5 box; other site
1126011004855	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1126011004856	glycerol kinase; Provisional; Region: glpK; PRK00047
1126011004857	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1126011004858	N- and C-terminal domain interface [polypeptide binding]; other site
1126011004859	active site
1126011004860	MgATP binding site [chemical binding]; other site
1126011004861	catalytic site [active]
1126011004862	metal binding site [ion binding]; metal-binding site
1126011004863	glycerol binding site [chemical binding]; other site
1126011004864	homotetramer interface [polypeptide binding]; other site
1126011004865	homodimer interface [polypeptide binding]; other site
1126011004866	FBP binding site [chemical binding]; other site
1126011004867	protein IIAGlc interface [polypeptide binding]; other site
1126011004868	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1126011004869	amphipathic channel; other site
1126011004870	Asn-Pro-Ala signature motifs; other site
1126011004871	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1126011004872	hypothetical protein; Provisional; Region: PRK14553
1126011004873	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1126011004874	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1126011004875	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1126011004876	homodimer interface [polypeptide binding]; other site
1126011004877	oligonucleotide binding site [chemical binding]; other site
1126011004878	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1126011004879	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1126011004880	Switch I; other site
1126011004881	Switch II; other site
1126011004882	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1126011004883	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1126011004884	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891
1126011004885	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1126011004886	Protein of unknown function (DUF972); Region: DUF972; pfam06156
1126011004887	rod shape-determining protein MreC; Region: MreC; pfam04085
1126011004888	rod shape-determining protein MreB; Provisional; Region: PRK13927
1126011004889	MreB and similar proteins; Region: MreB_like; cd10225
1126011004890	nucleotide binding site [chemical binding]; other site
1126011004891	Mg binding site [ion binding]; other site
1126011004892	putative protofilament interaction site [polypeptide binding]; other site
1126011004893	RodZ interaction site [polypeptide binding]; other site
1126011004894	hypothetical protein; Reviewed; Region: PRK00024
1126011004895	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1126011004896	MPN+ (JAMM) motif; other site
1126011004897	Zinc-binding site [ion binding]; other site
1126011004898	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1126011004899	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1126011004900	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1126011004901	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1126011004902	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1126011004903	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1126011004904	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1126011004905	active site
1126011004906	HIGH motif; other site
1126011004907	nucleotide binding site [chemical binding]; other site
1126011004908	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1126011004909	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1126011004910	active site
1126011004911	KMSKS motif; other site
1126011004912	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1126011004913	tRNA binding surface [nucleotide binding]; other site
1126011004914	anticodon binding site; other site
1126011004915	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1126011004916	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1126011004917	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1126011004918	inhibitor-cofactor binding pocket; inhibition site
1126011004919	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011004920	catalytic residue [active]
1126011004921	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1126011004922	dimer interface [polypeptide binding]; other site
1126011004923	active site
1126011004924	Schiff base residues; other site
1126011004925	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1126011004926	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1126011004927	active site
1126011004928	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1126011004929	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1126011004930	domain interfaces; other site
1126011004931	active site
1126011004932	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1126011004933	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1126011004934	tRNA; other site
1126011004935	putative tRNA binding site [nucleotide binding]; other site
1126011004936	putative NADP binding site [chemical binding]; other site
1126011004937	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1126011004938	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1126011004939	G1 box; other site
1126011004940	GTP/Mg2+ binding site [chemical binding]; other site
1126011004941	Switch I region; other site
1126011004942	G2 box; other site
1126011004943	G3 box; other site
1126011004944	Switch II region; other site
1126011004945	G4 box; other site
1126011004946	G5 box; other site
1126011004947	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1126011004948	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1126011004949	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1126011004950	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1126011004951	active site
1126011004952	dimer interface [polypeptide binding]; other site
1126011004953	motif 1; other site
1126011004954	motif 2; other site
1126011004955	motif 3; other site
1126011004956	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1126011004957	anticodon binding site; other site
1126011004958	primosomal protein DnaI; Reviewed; Region: PRK08939
1126011004959	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
1126011004960	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
1126011004961	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1126011004962	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1126011004963	ATP cone domain; Region: ATP-cone; pfam03477
1126011004964	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1126011004965	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1126011004966	CoA-binding site [chemical binding]; other site
1126011004967	ATP-binding [chemical binding]; other site
1126011004968	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1126011004969	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1126011004970	DNA binding site [nucleotide binding]
1126011004971	catalytic residue [active]
1126011004972	H2TH interface [polypeptide binding]; other site
1126011004973	putative catalytic residues [active]
1126011004974	turnover-facilitating residue; other site
1126011004975	intercalation triad [nucleotide binding]; other site
1126011004976	8OG recognition residue [nucleotide binding]; other site
1126011004977	putative reading head residues; other site
1126011004978	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1126011004979	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1126011004980	DNA polymerase I; Provisional; Region: PRK05755
1126011004981	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1126011004982	active site
1126011004983	metal binding site 1 [ion binding]; metal-binding site
1126011004984	putative 5' ssDNA interaction site; other site
1126011004985	metal binding site 3; metal-binding site
1126011004986	metal binding site 2 [ion binding]; metal-binding site
1126011004987	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1126011004988	putative DNA binding site [nucleotide binding]; other site
1126011004989	putative metal binding site [ion binding]; other site
1126011004990	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1126011004991	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1126011004992	active site
1126011004993	DNA binding site [nucleotide binding]
1126011004994	catalytic site [active]
1126011004995	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1126011004996	isocitrate dehydrogenase; Validated; Region: PRK07362
1126011004997	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
1126011004998	dimer interface [polypeptide binding]; other site
1126011004999	Citrate synthase; Region: Citrate_synt; pfam00285
1126011005000	active site
1126011005001	citrylCoA binding site [chemical binding]; other site
1126011005002	oxalacetate/citrate binding site [chemical binding]; other site
1126011005003	coenzyme A binding site [chemical binding]; other site
1126011005004	catalytic triad [active]
1126011005005	Protein of unknown function (DUF441); Region: DUF441; pfam04284
1126011005006	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1126011005007	pyruvate kinase; Provisional; Region: PRK06354
1126011005008	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1126011005009	domain interfaces; other site
1126011005010	active site
1126011005011	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1126011005012	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1126011005013	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1126011005014	active site
1126011005015	ADP/pyrophosphate binding site [chemical binding]; other site
1126011005016	dimerization interface [polypeptide binding]; other site
1126011005017	allosteric effector site; other site
1126011005018	fructose-1,6-bisphosphate binding site; other site
1126011005019	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1126011005020	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1126011005021	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1126011005022	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
1126011005023	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1126011005024	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
1126011005025	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1126011005026	active site
1126011005027	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1126011005028	generic binding surface I; other site
1126011005029	generic binding surface II; other site
1126011005030	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1126011005031	DHH family; Region: DHH; pfam01368
1126011005032	DHHA1 domain; Region: DHHA1; pfam02272
1126011005033	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
1126011005034	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1126011005035	DNA-binding site [nucleotide binding]; DNA binding site
1126011005036	DRTGG domain; Region: DRTGG; pfam07085
1126011005037	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
1126011005038	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1126011005039	active site 2 [active]
1126011005040	active site 1 [active]
1126011005041	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1126011005042	metal-dependent hydrolase; Provisional; Region: PRK00685
1126011005043	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1126011005044	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1126011005045	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1126011005046	active site
1126011005047	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1126011005048	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1126011005049	hexamer interface [polypeptide binding]; other site
1126011005050	ligand binding site [chemical binding]; other site
1126011005051	putative active site [active]
1126011005052	NAD(P) binding site [chemical binding]; other site
1126011005053	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1126011005054	Ligand Binding Site [chemical binding]; other site
1126011005055	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1126011005056	propionate/acetate kinase; Provisional; Region: PRK12379
1126011005057	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1126011005058	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005059	S-adenosylmethionine binding site [chemical binding]; other site
1126011005060	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1126011005061	dimer interface [polypeptide binding]; other site
1126011005062	catalytic triad [active]
1126011005063	peroxidatic and resolving cysteines [active]
1126011005064	RDD family; Region: RDD; pfam06271
1126011005065	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1126011005066	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1126011005067	tandem repeat interface [polypeptide binding]; other site
1126011005068	oligomer interface [polypeptide binding]; other site
1126011005069	active site residues [active]
1126011005070	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03501
1126011005071	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1126011005072	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1126011005073	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1126011005074	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1126011005075	acetylornithine aminotransferase; Provisional; Region: argD; PRK02936
1126011005076	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1126011005077	inhibitor-cofactor binding pocket; inhibition site
1126011005078	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005079	catalytic residue [active]
1126011005080	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1126011005081	nucleotide binding site [chemical binding]; other site
1126011005082	N-acetyl-L-glutamate binding site [chemical binding]; other site
1126011005083	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1126011005084	heterotetramer interface [polypeptide binding]; other site
1126011005085	active site pocket [active]
1126011005086	cleavage site
1126011005087	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
1126011005088	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1126011005089	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
1126011005090	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1126011005091	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1126011005092	Ligand Binding Site [chemical binding]; other site
1126011005093	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1126011005094	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1126011005095	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011005096	catalytic residue [active]
1126011005097	Negative regulator of septation ring formation [Cell division and chromosome partitioning]; Region: EzrA; COG4477
1126011005098	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1126011005099	GAF domain; Region: GAF_2; pfam13185
1126011005100	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1126011005101	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1126011005102	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011005103	RNA binding surface [nucleotide binding]; other site
1126011005104	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
1126011005105	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1126011005106	active site
1126011005107	HIGH motif; other site
1126011005108	dimer interface [polypeptide binding]; other site
1126011005109	KMSKS motif; other site
1126011005110	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011005111	RNA binding surface [nucleotide binding]; other site
1126011005112	catabolite control protein A; Region: ccpA; TIGR01481
1126011005113	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011005114	DNA binding site [nucleotide binding]
1126011005115	domain linker motif; other site
1126011005116	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
1126011005117	dimerization interface [polypeptide binding]; other site
1126011005118	effector binding site; other site
1126011005119	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595
1126011005120	Chorismate mutase type II; Region: CM_2; cl00693
1126011005121	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1126011005122	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
1126011005123	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
1126011005124	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1126011005125	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1126011005126	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1126011005127	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1126011005128	dimer interface [polypeptide binding]; other site
1126011005129	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1126011005130	catalytic triad [active]
1126011005131	peroxidatic and resolving cysteines [active]
1126011005132	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1126011005133	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1126011005134	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1126011005135	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1126011005136	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1126011005137	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1126011005138	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1126011005139	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1126011005140	putative tRNA-binding site [nucleotide binding]; other site
1126011005141	hypothetical protein; Provisional; Region: PRK13668
1126011005142	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011005143	catalytic residues [active]
1126011005144	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
1126011005145	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1126011005146	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1126011005147	oligomer interface [polypeptide binding]; other site
1126011005148	active site
1126011005149	metal binding site [ion binding]; metal-binding site
1126011005150	Predicted small secreted protein [Function unknown]; Region: COG5584
1126011005151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1937
1126011005152	putative homodimer interface [polypeptide binding]; other site
1126011005153	putative homotetramer interface [polypeptide binding]; other site
1126011005154	putative allosteric switch controlling residues; other site
1126011005155	putative metal binding site [ion binding]; other site
1126011005156	putative homodimer-homodimer interface [polypeptide binding]; other site
1126011005157	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011005158	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005159	S-adenosylmethionine binding site [chemical binding]; other site
1126011005160	Phosphotransferase enzyme family; Region: APH; pfam01636
1126011005161	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1126011005162	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1126011005163	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011005164	putative substrate translocation pore; other site
1126011005165	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011005166	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011005167	MarR family; Region: MarR; pfam01047
1126011005168	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1126011005169	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
1126011005170	homodimer interface [polypeptide binding]; other site
1126011005171	substrate-cofactor binding pocket; other site
1126011005172	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005173	catalytic residue [active]
1126011005174	dipeptidase PepV; Reviewed; Region: PRK07318
1126011005175	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
1126011005176	active site
1126011005177	metal binding site [ion binding]; metal-binding site
1126011005178	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_39; cd04699
1126011005179	nudix motif; other site
1126011005180	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1126011005181	putative substrate binding site [chemical binding]; other site
1126011005182	putative ATP binding site [chemical binding]; other site
1126011005183	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1126011005184	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1126011005185	active site
1126011005186	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1126011005187	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1126011005188	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1126011005189	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1126011005190	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1126011005191	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1126011005192	substrate binding site [chemical binding]; other site
1126011005193	active site
1126011005194	catalytic residues [active]
1126011005195	heterodimer interface [polypeptide binding]; other site
1126011005196	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1126011005197	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1126011005198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005199	catalytic residue [active]
1126011005200	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1126011005201	active site
1126011005202	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1126011005203	active site
1126011005204	ribulose/triose binding site [chemical binding]; other site
1126011005205	phosphate binding site [ion binding]; other site
1126011005206	substrate (anthranilate) binding pocket [chemical binding]; other site
1126011005207	product (indole) binding pocket [chemical binding]; other site
1126011005208	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1126011005209	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1126011005210	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1126011005211	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1126011005212	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1126011005213	glutamine binding [chemical binding]; other site
1126011005214	catalytic triad [active]
1126011005215	anthranilate synthase component I; Provisional; Region: PRK13570
1126011005216	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1126011005217	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1126011005218	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1126011005219	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1126011005220	putative catalytic cysteine [active]
1126011005221	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1126011005222	putative active site [active]
1126011005223	metal binding site [ion binding]; metal-binding site
1126011005224	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1126011005225	dimer interface [polypeptide binding]; other site
1126011005226	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011005227	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011005228	Walker A/P-loop; other site
1126011005229	ATP binding site [chemical binding]; other site
1126011005230	Q-loop/lid; other site
1126011005231	ABC transporter signature motif; other site
1126011005232	Walker B; other site
1126011005233	D-loop; other site
1126011005234	H-loop/switch region; other site
1126011005235	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1126011005236	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1126011005237	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1126011005238	putative dimer interface [polypeptide binding]; other site
1126011005239	catalytic triad [active]
1126011005240	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1126011005241	aconitate hydratase; Validated; Region: PRK09277
1126011005242	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1126011005243	substrate binding site [chemical binding]; other site
1126011005244	ligand binding site [chemical binding]; other site
1126011005245	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1126011005246	substrate binding site [chemical binding]; other site
1126011005247	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011005248	Heat induced stress protein YflT; Region: YflT; pfam11181
1126011005249	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1126011005250	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1126011005251	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011005252	ATP binding site [chemical binding]; other site
1126011005253	putative Mg++ binding site [ion binding]; other site
1126011005254	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011005255	nucleotide binding region [chemical binding]; other site
1126011005256	ATP-binding site [chemical binding]; other site
1126011005257	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1126011005258	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1126011005259	Walker A/P-loop; other site
1126011005260	ATP binding site [chemical binding]; other site
1126011005261	Q-loop/lid; other site
1126011005262	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1126011005263	ABC transporter signature motif; other site
1126011005264	Walker B; other site
1126011005265	D-loop; other site
1126011005266	H-loop/switch region; other site
1126011005267	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1126011005268	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1126011005269	active site
1126011005270	metal binding site [ion binding]; metal-binding site
1126011005271	DNA binding site [nucleotide binding]
1126011005272	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1126011005273	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1126011005274	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1126011005275	putative acyl-acceptor binding pocket; other site
1126011005276	Membrane protein involved in cytochrome C biogenesis [Posttranslational modification, protein turnover, chaperones]; Region: CcdC; COG4846
1126011005277	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011005278	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011005279	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1126011005280	Walker A/P-loop; other site
1126011005281	ATP binding site [chemical binding]; other site
1126011005282	Q-loop/lid; other site
1126011005283	ABC transporter signature motif; other site
1126011005284	Walker B; other site
1126011005285	D-loop; other site
1126011005286	H-loop/switch region; other site
1126011005287	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011005288	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1126011005289	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011005290	Walker A/P-loop; other site
1126011005291	ATP binding site [chemical binding]; other site
1126011005292	Q-loop/lid; other site
1126011005293	ABC transporter signature motif; other site
1126011005294	Walker B; other site
1126011005295	D-loop; other site
1126011005296	H-loop/switch region; other site
1126011005297	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
1126011005298	active site
1126011005299	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
1126011005300	elongation factor Ts; Provisional; Region: tsf; PRK09377
1126011005301	UBA/TS-N domain; Region: UBA; pfam00627
1126011005302	Elongation factor TS; Region: EF_TS; pfam00889
1126011005303	Elongation factor TS; Region: EF_TS; pfam00889
1126011005304	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1126011005305	rRNA interaction site [nucleotide binding]; other site
1126011005306	S8 interaction site; other site
1126011005307	putative laminin-1 binding site; other site
1126011005308	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
1126011005309	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1126011005310	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1126011005311	active site turn [active]
1126011005312	phosphorylation site [posttranslational modification]
1126011005313	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1126011005314	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1126011005315	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1126011005316	putative active site [active]
1126011005317	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011005318	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011005319	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011005320	putative active site [active]
1126011005321	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1126011005322	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1126011005323	HIGH motif; other site
1126011005324	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1126011005325	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1126011005326	active site
1126011005327	KMSKS motif; other site
1126011005328	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1126011005329	tRNA binding surface [nucleotide binding]; other site
1126011005330	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1126011005331	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1126011005332	FeS/SAM binding site; other site
1126011005333	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005334	S-adenosylmethionine binding site [chemical binding]; other site
1126011005335	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
1126011005336	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1126011005337	active site
1126011005338	dimer interface [polypeptide binding]; other site
1126011005339	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1126011005340	Ligand Binding Site [chemical binding]; other site
1126011005341	Molecular Tunnel; other site
1126011005342	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1126011005343	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1126011005344	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1126011005345	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1126011005346	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1126011005347	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1126011005348	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1126011005349	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011005350	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1126011005351	NAD binding site [chemical binding]; other site
1126011005352	dimer interface [polypeptide binding]; other site
1126011005353	substrate binding site [chemical binding]; other site
1126011005354	Protein of unknown function (DUF2584); Region: DUF2584; pfam10763
1126011005355	nucleoside triphosphatase YtkD; Region: nudix_YtkD; TIGR02705
1126011005356	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665
1126011005357	nudix motif; other site
1126011005358	Uncharacterized conserved protein [Function unknown]; Region: COG0759
1126011005359	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1126011005360	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
1126011005361	metal binding site [ion binding]; metal-binding site
1126011005362	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
1126011005363	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1126011005364	acyl-activating enzyme (AAE) consensus motif; other site
1126011005365	putative AMP binding site [chemical binding]; other site
1126011005366	putative active site [active]
1126011005367	putative CoA binding site [chemical binding]; other site
1126011005368	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1126011005369	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1126011005370	substrate binding site [chemical binding]; other site
1126011005371	oxyanion hole (OAH) forming residues; other site
1126011005372	trimer interface [polypeptide binding]; other site
1126011005373	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011005374	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
1126011005375	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1126011005376	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism]; Region: MenD; COG1165
1126011005377	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1126011005378	dimer interface [polypeptide binding]; other site
1126011005379	tetramer interface [polypeptide binding]; other site
1126011005380	PYR/PP interface [polypeptide binding]; other site
1126011005381	TPP binding site [chemical binding]; other site
1126011005382	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1126011005383	TPP-binding site; other site
1126011005384	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
1126011005385	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1126011005386	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1126011005387	UbiA prenyltransferase family; Region: UbiA; pfam01040
1126011005388	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
1126011005389	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1126011005390	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1126011005391	FAD binding site [chemical binding]; other site
1126011005392	cystathionine beta-lyase; Provisional; Region: PRK08064
1126011005393	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1126011005394	homodimer interface [polypeptide binding]; other site
1126011005395	substrate-cofactor binding pocket; other site
1126011005396	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005397	catalytic residue [active]
1126011005398	cystathionine gamma-synthase; Reviewed; Region: PRK08247
1126011005399	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1126011005400	homodimer interface [polypeptide binding]; other site
1126011005401	substrate-cofactor binding pocket; other site
1126011005402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005403	catalytic residue [active]
1126011005404	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1126011005405	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1126011005406	THF binding site; other site
1126011005407	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1126011005408	substrate binding site [chemical binding]; other site
1126011005409	THF binding site; other site
1126011005410	zinc-binding site [ion binding]; other site
1126011005411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011005412	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011005413	putative substrate translocation pore; other site
1126011005414	potential protein location (hypothetical protein MUO_08655 [Listeria monocytogenes 07PF0776]) that overlaps RNA (tRNA-K)
1126011005415	ferric uptake regulator; Provisional; Region: fur; PRK09462
1126011005416	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1126011005417	metal binding site 2 [ion binding]; metal-binding site
1126011005418	putative DNA binding helix; other site
1126011005419	metal binding site 1 [ion binding]; metal-binding site
1126011005420	dimer interface [polypeptide binding]; other site
1126011005421	structural Zn2+ binding site [ion binding]; other site
1126011005422	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1126011005423	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1126011005424	NAD binding site [chemical binding]; other site
1126011005425	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389
1126011005426	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1126011005427	inhibitor-cofactor binding pocket; inhibition site
1126011005428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011005429	catalytic residue [active]
1126011005430	Predicted membrane protein [Function unknown]; Region: COG4129
1126011005431	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1126011005432	hypothetical protein; Provisional; Region: PRK13662
1126011005433	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08063
1126011005434	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
1126011005435	putative NAD(P) binding site [chemical binding]; other site
1126011005436	active site
1126011005437	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1126011005438	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1126011005439	minor groove reading motif; other site
1126011005440	helix-hairpin-helix signature motif; other site
1126011005441	substrate binding pocket [chemical binding]; other site
1126011005442	active site
1126011005443	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1126011005444	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1126011005445	DNA binding and oxoG recognition site [nucleotide binding]
1126011005446	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1126011005447	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1126011005448	trimer interface [polypeptide binding]; other site
1126011005449	active site
1126011005450	WVELL protein; Region: WVELL; pfam14043
1126011005451	recombination regulator RecX; Provisional; Region: recX; PRK14135
1126011005452	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1126011005453	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1126011005454	NAD(P) binding site [chemical binding]; other site
1126011005455	active site
1126011005456	Predicted integral membrane protein [Function unknown]; Region: COG0392
1126011005457	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1126011005458	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1126011005459	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
1126011005460	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1126011005461	Cation efflux family; Region: Cation_efflux; pfam01545
1126011005462	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1126011005463	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1126011005464	PAS fold; Region: PAS_4; pfam08448
1126011005465	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1126011005466	putative active site [active]
1126011005467	heme pocket [chemical binding]; other site
1126011005468	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1126011005469	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1126011005470	dimer interface [polypeptide binding]; other site
1126011005471	putative CheW interface [polypeptide binding]; other site
1126011005472	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1126011005473	FosX, a fosfomycin resistance protein, catalyzes the addition of a water molecule to the C1 position of the antibiotic with inversion of configuration at C1; Region: FosX; cd08364
1126011005474	dimer interface [polypeptide binding]; other site
1126011005475	active site
1126011005476	Mn binding site [ion binding]; other site
1126011005477	TRAM domain; Region: TRAM; cl01282
1126011005478	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1126011005479	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005480	S-adenosylmethionine binding site [chemical binding]; other site
1126011005481	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1126011005482	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1126011005483	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1126011005484	Substrate-binding site [chemical binding]; other site
1126011005485	Substrate specificity [chemical binding]; other site
1126011005486	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
1126011005487	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4840
1126011005488	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
1126011005489	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1126011005490	active site
1126011005491	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1126011005492	flavodoxin, short chain; Region: flav_short; TIGR01753
1126011005493	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1126011005494	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1126011005495	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011005496	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011005497	putative substrate translocation pore; other site
1126011005498	rod-share determining protein MreBH; Provisional; Region: PRK13929
1126011005499	MreB and similar proteins; Region: MreB_like; cd10225
1126011005500	nucleotide binding site [chemical binding]; other site
1126011005501	Mg binding site [ion binding]; other site
1126011005502	putative protofilament interaction site [polypeptide binding]; other site
1126011005503	RodZ interaction site [polypeptide binding]; other site
1126011005504	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005505	S-adenosylmethionine binding site [chemical binding]; other site
1126011005506	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011005507	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011005508	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1126011005509	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1126011005510	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011005511	methionine cluster; other site
1126011005512	active site
1126011005513	phosphorylation site [posttranslational modification]
1126011005514	metal binding site [ion binding]; metal-binding site
1126011005515	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011005516	active site
1126011005517	P-loop; other site
1126011005518	phosphorylation site [posttranslational modification]
1126011005519	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1126011005520	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1126011005521	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011005522	Walker A motif; other site
1126011005523	ATP binding site [chemical binding]; other site
1126011005524	Walker B motif; other site
1126011005525	arginine finger; other site
1126011005526	Transcriptional antiterminator [Transcription]; Region: COG3933
1126011005527	PRD domain; Region: PRD; pfam00874
1126011005528	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011005529	active pocket/dimerization site; other site
1126011005530	active site
1126011005531	phosphorylation site [posttranslational modification]
1126011005532	PRD domain; Region: PRD; pfam00874
1126011005533	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1126011005534	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1126011005535	ATP binding site [chemical binding]; other site
1126011005536	putative Mg++ binding site [ion binding]; other site
1126011005537	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011005538	nucleotide binding region [chemical binding]; other site
1126011005539	ATP-binding site [chemical binding]; other site
1126011005540	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1126011005541	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011005542	Walker A/P-loop; other site
1126011005543	ATP binding site [chemical binding]; other site
1126011005544	Q-loop/lid; other site
1126011005545	ABC transporter signature motif; other site
1126011005546	Walker B; other site
1126011005547	D-loop; other site
1126011005548	H-loop/switch region; other site
1126011005549	Predicted transcriptional regulators [Transcription]; Region: COG1725
1126011005550	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011005551	DNA-binding site [nucleotide binding]; DNA binding site
1126011005552	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011005553	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011005554	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011005555	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011005556	DNA binding site [nucleotide binding]
1126011005557	domain linker motif; other site
1126011005558	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1126011005559	dimerization interface [polypeptide binding]; other site
1126011005560	ligand binding site [chemical binding]; other site
1126011005561	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1126011005562	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1126011005563	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1126011005564	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1126011005565	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1126011005566	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011005567	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011005568	dimer interface [polypeptide binding]; other site
1126011005569	conserved gate region; other site
1126011005570	putative PBP binding loops; other site
1126011005571	ABC-ATPase subunit interface; other site
1126011005572	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011005573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011005574	dimer interface [polypeptide binding]; other site
1126011005575	conserved gate region; other site
1126011005576	putative PBP binding loops; other site
1126011005577	ABC-ATPase subunit interface; other site
1126011005578	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1126011005579	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1126011005580	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1126011005581	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1126011005582	active site
1126011005583	dimer interface [polypeptide binding]; other site
1126011005584	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1126011005585	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1126011005586	active site
1126011005587	FMN binding site [chemical binding]; other site
1126011005588	substrate binding site [chemical binding]; other site
1126011005589	3Fe-4S cluster binding site [ion binding]; other site
1126011005590	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1126011005591	domain interface; other site
1126011005592	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011005593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011005594	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1126011005595	putative dimerization interface [polypeptide binding]; other site
1126011005596	Predicted acetyltransferase [General function prediction only]; Region: COG3153
1126011005597	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1126011005598	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1126011005599	putative active site [active]
1126011005600	metal binding site [ion binding]; metal-binding site
1126011005601	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1126011005602	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1126011005603	substrate binding pocket [chemical binding]; other site
1126011005604	membrane-bound complex binding site; other site
1126011005605	hinge residues; other site
1126011005606	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011005607	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011005608	Walker A/P-loop; other site
1126011005609	ATP binding site [chemical binding]; other site
1126011005610	Q-loop/lid; other site
1126011005611	ABC transporter signature motif; other site
1126011005612	Walker B; other site
1126011005613	D-loop; other site
1126011005614	H-loop/switch region; other site
1126011005615	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011005616	dimer interface [polypeptide binding]; other site
1126011005617	conserved gate region; other site
1126011005618	putative PBP binding loops; other site
1126011005619	ABC-ATPase subunit interface; other site
1126011005620	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1126011005621	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1126011005622	dimer interface [polypeptide binding]; other site
1126011005623	phosphorylation site [posttranslational modification]
1126011005624	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011005625	ATP binding site [chemical binding]; other site
1126011005626	Mg2+ binding site [ion binding]; other site
1126011005627	G-X-G motif; other site
1126011005628	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1126011005629	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1126011005630	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1126011005631	active site
1126011005632	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1126011005633	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
1126011005634	putative NAD(P) binding site [chemical binding]; other site
1126011005635	active site
1126011005636	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011005637	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011005638	active site
1126011005639	phosphorylation site [posttranslational modification]
1126011005640	intermolecular recognition site; other site
1126011005641	dimerization interface [polypeptide binding]; other site
1126011005642	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011005643	DNA binding site [nucleotide binding]
1126011005644	FtsX-like permease family; Region: FtsX; pfam02687
1126011005645	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1126011005646	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011005647	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011005648	Walker A/P-loop; other site
1126011005649	ATP binding site [chemical binding]; other site
1126011005650	Q-loop/lid; other site
1126011005651	ABC transporter signature motif; other site
1126011005652	Walker B; other site
1126011005653	D-loop; other site
1126011005654	H-loop/switch region; other site
1126011005655	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1126011005656	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1126011005657	ADP binding site [chemical binding]; other site
1126011005658	magnesium binding site [ion binding]; other site
1126011005659	putative shikimate binding site; other site
1126011005660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
1126011005661	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1126011005662	TRAM domain; Region: TRAM; pfam01938
1126011005663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005664	S-adenosylmethionine binding site [chemical binding]; other site
1126011005665	putative lipid kinase; Reviewed; Region: PRK13337
1126011005666	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1126011005667	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1126011005668	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1126011005669	GatB domain; Region: GatB_Yqey; smart00845
1126011005670	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1126011005671	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1126011005672	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1126011005673	Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851
1126011005674	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
1126011005675	putative dimer interface [polypeptide binding]; other site
1126011005676	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
1126011005677	putative dimer interface [polypeptide binding]; other site
1126011005678	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1126011005679	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1126011005680	nucleotide binding pocket [chemical binding]; other site
1126011005681	K-X-D-G motif; other site
1126011005682	catalytic site [active]
1126011005683	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1126011005684	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1126011005685	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1126011005686	Dimer interface [polypeptide binding]; other site
1126011005687	BRCT sequence motif; other site
1126011005688	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1126011005689	Part of AAA domain; Region: AAA_19; pfam13245
1126011005690	Family description; Region: UvrD_C_2; pfam13538
1126011005691	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
1126011005692	PcrB family; Region: PcrB; pfam01884
1126011005693	substrate binding site [chemical binding]; other site
1126011005694	putative active site [active]
1126011005695	dimer interface [polypeptide binding]; other site
1126011005696	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1126011005697	Na2 binding site [ion binding]; other site
1126011005698	putative substrate binding site 1 [chemical binding]; other site
1126011005699	Na binding site 1 [ion binding]; other site
1126011005700	putative substrate binding site 2 [chemical binding]; other site
1126011005701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4496
1126011005702	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1126011005703	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1126011005704	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1126011005705	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1126011005706	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1126011005707	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1126011005708	purine monophosphate binding site [chemical binding]; other site
1126011005709	dimer interface [polypeptide binding]; other site
1126011005710	putative catalytic residues [active]
1126011005711	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1126011005712	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1126011005713	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
1126011005714	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1126011005715	active site
1126011005716	substrate binding site [chemical binding]; other site
1126011005717	cosubstrate binding site; other site
1126011005718	catalytic site [active]
1126011005719	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1126011005720	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1126011005721	dimerization interface [polypeptide binding]; other site
1126011005722	putative ATP binding site [chemical binding]; other site
1126011005723	amidophosphoribosyltransferase; Provisional; Region: PRK06781
1126011005724	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1126011005725	active site
1126011005726	tetramer interface [polypeptide binding]; other site
1126011005727	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011005728	active site
1126011005729	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1126011005730	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1126011005731	dimerization interface [polypeptide binding]; other site
1126011005732	ATP binding site [chemical binding]; other site
1126011005733	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1126011005734	dimerization interface [polypeptide binding]; other site
1126011005735	ATP binding site [chemical binding]; other site
1126011005736	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1126011005737	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1126011005738	putative active site [active]
1126011005739	catalytic triad [active]
1126011005740	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
1126011005741	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1126011005742	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1126011005743	ATP binding site [chemical binding]; other site
1126011005744	active site
1126011005745	substrate binding site [chemical binding]; other site
1126011005746	adenylosuccinate lyase; Provisional; Region: PRK07492
1126011005747	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1126011005748	tetramer interface [polypeptide binding]; other site
1126011005749	active site
1126011005750	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1126011005751	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1126011005752	NAD binding site [chemical binding]; other site
1126011005753	ATP-grasp domain; Region: ATP-grasp; pfam02222
1126011005754	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1126011005755	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4843
1126011005756	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011005757	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1126011005758	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011005759	Zn2+ binding site [ion binding]; other site
1126011005760	Mg2+ binding site [ion binding]; other site
1126011005761	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1126011005762	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1126011005763	Walker A/P-loop; other site
1126011005764	ATP binding site [chemical binding]; other site
1126011005765	Q-loop/lid; other site
1126011005766	ABC transporter signature motif; other site
1126011005767	Walker B; other site
1126011005768	D-loop; other site
1126011005769	H-loop/switch region; other site
1126011005770	peptidase T; Region: peptidase-T; TIGR01882
1126011005771	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1126011005772	metal binding site [ion binding]; metal-binding site
1126011005773	dimer interface [polypeptide binding]; other site
1126011005774	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3797
1126011005775	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1126011005776	active site
1126011005777	putative catalytic site [active]
1126011005778	DNA binding site [nucleotide binding]
1126011005779	putative phosphate binding site [ion binding]; other site
1126011005780	metal binding site A [ion binding]; metal-binding site
1126011005781	AP binding site [nucleotide binding]; other site
1126011005782	metal binding site B [ion binding]; metal-binding site
1126011005783	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1126011005784	23S rRNA binding site [nucleotide binding]; other site
1126011005785	L21 binding site [polypeptide binding]; other site
1126011005786	L13 binding site [polypeptide binding]; other site
1126011005787	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1126011005788	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1126011005789	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1126011005790	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1126011005791	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011005792	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011005793	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011005794	Substrate binding site [chemical binding]; other site
1126011005795	Leucine rich repeat; Region: LRR_8; pfam13855
1126011005796	LRR adjacent; Region: LRR_adjacent; pfam08191
1126011005797	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1126011005798	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1126011005799	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1126011005800	DNA binding residues [nucleotide binding]
1126011005801	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1126011005802	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1126011005803	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011005804	Putative heavy-metal-binding; Region: YbjQ_1; pfam01906
1126011005805	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1126011005806	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1126011005807	RimM N-terminal domain; Region: RimM; pfam01782
1126011005808	PRC-barrel domain; Region: PRC; pfam05239
1126011005809	Protein of unknown function (DUF2869); Region: DUF2869; pfam11068
1126011005810	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1126011005811	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1126011005812	catalytic triad [active]
1126011005813	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1126011005814	KH domain; Region: KH_4; pfam13083
1126011005815	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1126011005816	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
1126011005817	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1126011005818	signal recognition particle protein; Provisional; Region: PRK10867
1126011005819	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1126011005820	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1126011005821	P loop; other site
1126011005822	GTP binding site [chemical binding]; other site
1126011005823	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1126011005824	putative DNA-binding protein; Validated; Region: PRK00118
1126011005825	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
1126011005826	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1126011005827	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1126011005828	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1126011005829	P loop; other site
1126011005830	GTP binding site [chemical binding]; other site
1126011005831	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1126011005832	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1126011005833	Walker A/P-loop; other site
1126011005834	ATP binding site [chemical binding]; other site
1126011005835	Q-loop/lid; other site
1126011005836	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1126011005837	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
1126011005838	linker region; other site
1126011005839	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1126011005840	ABC transporter signature motif; other site
1126011005841	Walker B; other site
1126011005842	D-loop; other site
1126011005843	H-loop/switch region; other site
1126011005844	ribonuclease III; Reviewed; Region: rnc; PRK00102
1126011005845	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1126011005846	dimerization interface [polypeptide binding]; other site
1126011005847	active site
1126011005848	metal binding site [ion binding]; metal-binding site
1126011005849	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1126011005850	dsRNA binding site [nucleotide binding]; other site
1126011005851	acyl carrier protein; Provisional; Region: acpP; PRK00982
1126011005852	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1126011005853	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1126011005854	NAD(P) binding site [chemical binding]; other site
1126011005855	homotetramer interface [polypeptide binding]; other site
1126011005856	homodimer interface [polypeptide binding]; other site
1126011005857	active site
1126011005858	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1126011005859	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1126011005860	putative phosphate acyltransferase; Provisional; Region: PRK05331
1126011005861	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
1126011005862	HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]; Region: PaaI; COG2050
1126011005863	active site 2 [active]
1126011005864	active site 1 [active]
1126011005865	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1126011005866	Y-family of DNA polymerases; Region: PolY; cl12025
1126011005867	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1126011005868	generic binding surface II; other site
1126011005869	ssDNA binding site; other site
1126011005870	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011005871	ATP binding site [chemical binding]; other site
1126011005872	putative Mg++ binding site [ion binding]; other site
1126011005873	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011005874	nucleotide binding region [chemical binding]; other site
1126011005875	ATP-binding site [chemical binding]; other site
1126011005876	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1126011005877	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1126011005878	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
1126011005879	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1126011005880	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
1126011005881	putative L-serine binding site [chemical binding]; other site
1126011005882	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1126011005883	DAK2 domain; Region: Dak2; pfam02734
1126011005884	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1126011005885	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1126011005886	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
1126011005887	Thiamine pyrophosphokinase; Region: TPK; cd07995
1126011005888	active site
1126011005889	dimerization interface [polypeptide binding]; other site
1126011005890	thiamine binding site [chemical binding]; other site
1126011005891	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1126011005892	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1126011005893	substrate binding site [chemical binding]; other site
1126011005894	hexamer interface [polypeptide binding]; other site
1126011005895	metal binding site [ion binding]; metal-binding site
1126011005896	GTPase RsgA; Reviewed; Region: PRK00098
1126011005897	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1126011005898	RNA binding site [nucleotide binding]; other site
1126011005899	homodimer interface [polypeptide binding]; other site
1126011005900	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1126011005901	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1126011005902	GTP/Mg2+ binding site [chemical binding]; other site
1126011005903	G4 box; other site
1126011005904	G1 box; other site
1126011005905	Switch I region; other site
1126011005906	G2 box; other site
1126011005907	G3 box; other site
1126011005908	Switch II region; other site
1126011005909	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1126011005910	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1126011005911	active site
1126011005912	ATP binding site [chemical binding]; other site
1126011005913	substrate binding site [chemical binding]; other site
1126011005914	activation loop (A-loop); other site
1126011005915	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
1126011005916	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1126011005917	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1126011005918	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1126011005919	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1126011005920	Protein phosphatase 2C; Region: PP2C; pfam00481
1126011005921	active site
1126011005922	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1126011005923	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
1126011005924	putative RNA binding site [nucleotide binding]; other site
1126011005925	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011005926	S-adenosylmethionine binding site [chemical binding]; other site
1126011005927	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1126011005928	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1126011005929	putative active site [active]
1126011005930	substrate binding site [chemical binding]; other site
1126011005931	putative cosubstrate binding site; other site
1126011005932	catalytic site [active]
1126011005933	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1126011005934	substrate binding site [chemical binding]; other site
1126011005935	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1126011005936	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011005937	ATP binding site [chemical binding]; other site
1126011005938	putative Mg++ binding site [ion binding]; other site
1126011005939	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011005940	ATP-binding site [chemical binding]; other site
1126011005941	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1126011005942	Flavoprotein; Region: Flavoprotein; pfam02441
1126011005943	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1126011005944	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1126011005945	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1126011005946	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1126011005947	catalytic site [active]
1126011005948	G-X2-G-X-G-K; other site
1126011005949	Uncharacterized stress-induced protein [Function unknown]; Region: COG1561
1126011005950	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1126011005951	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1126011005952	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
1126011005953	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1126011005954	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
1126011005955	putative NAD(P) binding site [chemical binding]; other site
1126011005956	homodimer interface [polypeptide binding]; other site
1126011005957	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011005958	active site
1126011005959	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1126011005960	active site
1126011005961	dimer interface [polypeptide binding]; other site
1126011005962	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1126011005963	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1126011005964	heterodimer interface [polypeptide binding]; other site
1126011005965	active site
1126011005966	FMN binding site [chemical binding]; other site
1126011005967	homodimer interface [polypeptide binding]; other site
1126011005968	substrate binding site [chemical binding]; other site
1126011005969	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1126011005970	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1126011005971	FAD binding pocket [chemical binding]; other site
1126011005972	FAD binding motif [chemical binding]; other site
1126011005973	phosphate binding motif [ion binding]; other site
1126011005974	beta-alpha-beta structure motif; other site
1126011005975	NAD binding pocket [chemical binding]; other site
1126011005976	Iron coordination center [ion binding]; other site
1126011005977	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1126011005978	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1126011005979	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1126011005980	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1126011005981	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1126011005982	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1126011005983	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1126011005984	IMP binding site; other site
1126011005985	dimer interface [polypeptide binding]; other site
1126011005986	interdomain contacts; other site
1126011005987	partial ornithine binding site; other site
1126011005988	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1126011005989	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1126011005990	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1126011005991	catalytic site [active]
1126011005992	subunit interface [polypeptide binding]; other site
1126011005993	dihydroorotase; Validated; Region: pyrC; PRK09357
1126011005994	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1126011005995	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1126011005996	active site
1126011005997	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1126011005998	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1126011005999	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1126011006000	uracil transporter; Provisional; Region: PRK10720
1126011006001	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1126011006002	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011006003	active site
1126011006004	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1126011006005	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1126011006006	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011006007	RNA binding surface [nucleotide binding]; other site
1126011006008	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1126011006009	active site
1126011006010	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1126011006011	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1126011006012	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1126011006013	multidrug efflux protein; Reviewed; Region: PRK01766
1126011006014	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1126011006015	cation binding site [ion binding]; other site
1126011006016	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1126011006017	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1126011006018	metal binding site [ion binding]; metal-binding site
1126011006019	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1126011006020	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011006021	ABC-ATPase subunit  interface; other site
1126011006022	dimer interface [polypeptide binding]; other site
1126011006023	putative PBP binding regions; other site
1126011006024	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1126011006025	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1126011006026	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011006027	MarR family; Region: MarR; pfam01047
1126011006028	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1126011006029	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1126011006030	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1126011006031	protein binding site [polypeptide binding]; other site
1126011006032	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1126011006033	Catalytic dyad [active]
1126011006034	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1126011006035	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1126011006036	metal-binding site [ion binding]
1126011006037	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1126011006038	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1126011006039	metal-binding site [ion binding]
1126011006040	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011006041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011006042	motif II; other site
1126011006043	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cl00846
1126011006044	putative homodimer interface [polypeptide binding]; other site
1126011006045	putative homotetramer interface [polypeptide binding]; other site
1126011006046	putative allosteric switch controlling residues; other site
1126011006047	putative metal binding site [ion binding]; other site
1126011006048	putative homodimer-homodimer interface [polypeptide binding]; other site
1126011006049	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1126011006050	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1126011006051	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1126011006052	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1126011006053	hypothetical protein; Provisional; Region: PRK13672
1126011006054	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011006055	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011006056	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1126011006057	SelR domain; Region: SelR; pfam01641
1126011006058	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1126011006059	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4698
1126011006060	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
1126011006061	active site
1126011006062	catalytic triad [active]
1126011006063	oxyanion hole [active]
1126011006064	EDD domain protein, DegV family; Region: DegV; TIGR00762
1126011006065	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1126011006066	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
1126011006067	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1126011006068	HTH domain; Region: HTH_11; pfam08279
1126011006069	FOG: CBS domain [General function prediction only]; Region: COG0517
1126011006070	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
1126011006071	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1126011006072	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1126011006073	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1126011006074	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1126011006075	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1126011006076	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011006077	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1126011006078	Predicted membrane protein [Function unknown]; Region: COG4129
1126011006079	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1126011006080	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
1126011006081	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1126011006082	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1126011006083	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1126011006084	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1126011006085	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
1126011006086	Clostridial hydrophobic W; Region: ChW; pfam07538
1126011006087	Clostridial hydrophobic W; Region: ChW; pfam07538
1126011006088	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1126011006089	active site
1126011006090	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1126011006091	substrate binding site [chemical binding]; other site
1126011006092	metal binding site [ion binding]; metal-binding site
1126011006093	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1126011006094	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1126011006095	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1126011006096	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1126011006097	folate binding site [chemical binding]; other site
1126011006098	NADP+ binding site [chemical binding]; other site
1126011006099	thymidylate synthase; Region: thym_sym; TIGR03284
1126011006100	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1126011006101	dimerization interface [polypeptide binding]; other site
1126011006102	active site
1126011006103	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1126011006104	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1126011006105	Walker A/P-loop; other site
1126011006106	ATP binding site [chemical binding]; other site
1126011006107	Q-loop/lid; other site
1126011006108	ABC transporter signature motif; other site
1126011006109	Walker B; other site
1126011006110	D-loop; other site
1126011006111	H-loop/switch region; other site
1126011006112	ABC transporter; Region: ABC_tran_2; pfam12848
1126011006113	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011006114	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1126011006115	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1126011006116	Potassium binding sites [ion binding]; other site
1126011006117	Cesium cation binding sites [ion binding]; other site
1126011006118	manganese transport transcriptional regulator; Provisional; Region: PRK03902
1126011006119	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1126011006120	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1126011006121	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1126011006122	DNA-binding site [nucleotide binding]; DNA binding site
1126011006123	RNA-binding motif; other site
1126011006124	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1126011006125	RNA/DNA hybrid binding site [nucleotide binding]; other site
1126011006126	active site
1126011006127	5'-3' exonuclease; Region: 53EXOc; smart00475
1126011006128	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1126011006129	active site
1126011006130	metal binding site 1 [ion binding]; metal-binding site
1126011006131	putative 5' ssDNA interaction site; other site
1126011006132	metal binding site 3; metal-binding site
1126011006133	metal binding site 2 [ion binding]; metal-binding site
1126011006134	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1126011006135	putative DNA binding site [nucleotide binding]; other site
1126011006136	putative metal binding site [ion binding]; other site
1126011006137	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1126011006138	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
1126011006139	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
1126011006140	putative active site [active]
1126011006141	xanthine permease; Region: pbuX; TIGR03173
1126011006142	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011006143	active site
1126011006144	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1126011006145	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1126011006146	active site
1126011006147	Zn binding site [ion binding]; other site
1126011006148	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1126011006149	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1126011006150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1126011006151	cell division protein GpsB; Provisional; Region: PRK14127
1126011006152	DivIVA domain; Region: DivI1A_domain; TIGR03544
1126011006153	Interactor of ZYG-11; Region: ZYG-11_interact; pfam05884
1126011006154	hypothetical protein; Provisional; Region: PRK13660
1126011006155	Bacterial domain of unknown function (DUF1798); Region: DUF1798; pfam08807
1126011006156	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
1126011006157	Transglycosylase; Region: Transgly; pfam00912
1126011006158	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1126011006159	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1126011006160	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1126011006161	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1126011006162	minor groove reading motif; other site
1126011006163	helix-hairpin-helix signature motif; other site
1126011006164	substrate binding pocket [chemical binding]; other site
1126011006165	active site
1126011006166	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1126011006167	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
1126011006168	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1126011006169	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1126011006170	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
1126011006171	putative dimer interface [polypeptide binding]; other site
1126011006172	putative anticodon binding site; other site
1126011006173	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1126011006174	homodimer interface [polypeptide binding]; other site
1126011006175	motif 1; other site
1126011006176	motif 2; other site
1126011006177	active site
1126011006178	motif 3; other site
1126011006179	aspartate aminotransferase; Provisional; Region: PRK05764
1126011006180	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011006181	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011006182	homodimer interface [polypeptide binding]; other site
1126011006183	catalytic residue [active]
1126011006184	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
1126011006185	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1126011006186	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
1126011006187	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1126011006188	active site
1126011006189	catalytic site [active]
1126011006190	substrate binding site [chemical binding]; other site
1126011006191	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
1126011006192	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1126011006193	putative Mg++ binding site [ion binding]; other site
1126011006194	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1126011006195	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1126011006196	tetramerization interface [polypeptide binding]; other site
1126011006197	active site
1126011006198	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1126011006199	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1126011006200	active site
1126011006201	ATP-binding site [chemical binding]; other site
1126011006202	pantoate-binding site; other site
1126011006203	HXXH motif; other site
1126011006204	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1126011006205	active site
1126011006206	oligomerization interface [polypeptide binding]; other site
1126011006207	metal binding site [ion binding]; metal-binding site
1126011006208	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011006209	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1126011006210	catalytic residues [active]
1126011006211	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1126011006212	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1126011006213	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1126011006214	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1126011006215	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1126011006216	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1126011006217	active site
1126011006218	NTP binding site [chemical binding]; other site
1126011006219	metal binding triad [ion binding]; metal-binding site
1126011006220	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1126011006221	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1126011006222	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1126011006223	active site
1126011006224	dimer interfaces [polypeptide binding]; other site
1126011006225	catalytic residues [active]
1126011006226	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1126011006227	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1126011006228	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1126011006229	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1126011006230	homodimer interface [polypeptide binding]; other site
1126011006231	metal binding site [ion binding]; metal-binding site
1126011006232	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1126011006233	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011006234	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011006235	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011006236	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1126011006237	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1126011006238	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1126011006239	metal binding site [ion binding]; metal-binding site
1126011006240	active site
1126011006241	I-site; other site
1126011006242	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1126011006243	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1126011006244	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1126011006245	metal binding site [ion binding]; metal-binding site
1126011006246	active site
1126011006247	I-site; other site
1126011006248	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1126011006249	malate dehydrogenase; Provisional; Region: PRK13529
1126011006250	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1126011006251	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1126011006252	NAD(P) binding pocket [chemical binding]; other site
1126011006253	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1126011006254	Beta-lactamase; Region: Beta-lactamase; pfam00144
1126011006255	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1126011006256	Pyruvate formate lyase 1; Region: PFL1; cd01678
1126011006257	coenzyme A binding site [chemical binding]; other site
1126011006258	active site
1126011006259	catalytic residues [active]
1126011006260	glycine loop; other site
1126011006261	HI0933-like protein; Region: HI0933_like; pfam03486
1126011006262	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011006263	Predicted Zn-dependent protease [General function prediction only]; Region: COG2738
1126011006264	Predicted membrane protein [Function unknown]; Region: COG4347
1126011006265	hypothetical protein; Provisional; Region: PRK03636
1126011006266	UPF0302 domain; Region: UPF0302; pfam08864
1126011006267	IDEAL domain; Region: IDEAL; pfam08858
1126011006268	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1126011006269	binding surface
1126011006270	TPR motif; other site
1126011006271	TPR repeat; Region: TPR_11; pfam13414
1126011006272	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011006273	binding surface
1126011006274	TPR motif; other site
1126011006275	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1126011006276	binding surface
1126011006277	TPR motif; other site
1126011006278	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1126011006279	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1126011006280	hinge; other site
1126011006281	active site
1126011006282	prephenate dehydrogenase; Validated; Region: PRK06545
1126011006283	prephenate dehydrogenase; Validated; Region: PRK08507
1126011006284	C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909
1126011006285	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
1126011006286	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011006287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011006288	homodimer interface [polypeptide binding]; other site
1126011006289	catalytic residue [active]
1126011006290	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
1126011006291	homotrimer interaction site [polypeptide binding]; other site
1126011006292	active site
1126011006293	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1126011006294	active site
1126011006295	dimer interface [polypeptide binding]; other site
1126011006296	metal binding site [ion binding]; metal-binding site
1126011006297	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1126011006298	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1126011006299	Tetramer interface [polypeptide binding]; other site
1126011006300	active site
1126011006301	FMN-binding site [chemical binding]; other site
1126011006302	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1126011006303	active site
1126011006304	multimer interface [polypeptide binding]; other site
1126011006305	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1126011006306	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1126011006307	substrate binding pocket [chemical binding]; other site
1126011006308	chain length determination region; other site
1126011006309	substrate-Mg2+ binding site; other site
1126011006310	catalytic residues [active]
1126011006311	aspartate-rich region 1; other site
1126011006312	active site lid residues [active]
1126011006313	aspartate-rich region 2; other site
1126011006314	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1126011006315	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011006316	S-adenosylmethionine binding site [chemical binding]; other site
1126011006317	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307
1126011006318	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1126011006319	homodecamer interface [polypeptide binding]; other site
1126011006320	GTP cyclohydrolase I; Provisional; Region: PLN03044
1126011006321	active site
1126011006322	putative catalytic site residues [active]
1126011006323	zinc binding site [ion binding]; other site
1126011006324	GTP-CH-I/GFRP interaction surface; other site
1126011006325	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1126011006326	IHF dimer interface [polypeptide binding]; other site
1126011006327	IHF - DNA interface [nucleotide binding]; other site
1126011006328	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
1126011006329	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1126011006330	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1126011006331	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1126011006332	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1126011006333	GTP-binding protein Der; Reviewed; Region: PRK00093
1126011006334	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1126011006335	G1 box; other site
1126011006336	GTP/Mg2+ binding site [chemical binding]; other site
1126011006337	Switch I region; other site
1126011006338	G2 box; other site
1126011006339	Switch II region; other site
1126011006340	G3 box; other site
1126011006341	G4 box; other site
1126011006342	G5 box; other site
1126011006343	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1126011006344	G1 box; other site
1126011006345	GTP/Mg2+ binding site [chemical binding]; other site
1126011006346	Switch I region; other site
1126011006347	G2 box; other site
1126011006348	G3 box; other site
1126011006349	Switch II region; other site
1126011006350	G4 box; other site
1126011006351	G5 box; other site
1126011006352	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1126011006353	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1126011006354	RNA binding site [nucleotide binding]; other site
1126011006355	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1126011006356	RNA binding site [nucleotide binding]; other site
1126011006357	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1126011006358	RNA binding site [nucleotide binding]; other site
1126011006359	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1126011006360	RNA binding site [nucleotide binding]; other site
1126011006361	cytidylate kinase; Provisional; Region: cmk; PRK00023
1126011006362	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1126011006363	CMP-binding site; other site
1126011006364	The sites determining sugar specificity; other site
1126011006365	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1126011006366	active site
1126011006367	homotetramer interface [polypeptide binding]; other site
1126011006368	homodimer interface [polypeptide binding]; other site
1126011006369	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011006370	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1126011006371	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1126011006372	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011006373	ATP binding site [chemical binding]; other site
1126011006374	putative Mg++ binding site [ion binding]; other site
1126011006375	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011006376	nucleotide binding region [chemical binding]; other site
1126011006377	ATP-binding site [chemical binding]; other site
1126011006378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
1126011006379	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
1126011006380	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006381	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006382	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006383	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006384	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006385	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006386	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1126011006387	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011006388	Predicted membrane protein [Function unknown]; Region: COG3601
1126011006389	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1126011006390	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1126011006391	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011006392	dimerization interface [polypeptide binding]; other site
1126011006393	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1126011006394	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011006395	dimer interface [polypeptide binding]; other site
1126011006396	phosphorylation site [posttranslational modification]
1126011006397	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011006398	ATP binding site [chemical binding]; other site
1126011006399	Mg2+ binding site [ion binding]; other site
1126011006400	G-X-G motif; other site
1126011006401	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011006402	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011006403	active site
1126011006404	phosphorylation site [posttranslational modification]
1126011006405	intermolecular recognition site; other site
1126011006406	dimerization interface [polypeptide binding]; other site
1126011006407	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011006408	DNA binding site [nucleotide binding]
1126011006409	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1126011006410	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011006411	RNA binding surface [nucleotide binding]; other site
1126011006412	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1126011006413	active site
1126011006414	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
1126011006415	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1126011006416	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1126011006417	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1126011006418	active site
1126011006419	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1126011006420	substrate binding site [chemical binding]; other site
1126011006421	catalytic residues [active]
1126011006422	dimer interface [polypeptide binding]; other site
1126011006423	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1126011006424	phosphopentomutase; Provisional; Region: PRK05362
1126011006425	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1126011006426	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1126011006427	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1126011006428	active site
1126011006429	Int/Topo IB signature motif; other site
1126011006430	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1126011006431	metal binding site 2 [ion binding]; metal-binding site
1126011006432	putative DNA binding helix; other site
1126011006433	metal binding site 1 [ion binding]; metal-binding site
1126011006434	dimer interface [polypeptide binding]; other site
1126011006435	structural Zn2+ binding site [ion binding]; other site
1126011006436	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1126011006437	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011006438	ABC-ATPase subunit  interface; other site
1126011006439	dimer interface [polypeptide binding]; other site
1126011006440	putative PBP binding regions; other site
1126011006441	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1126011006442	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011006443	ABC-ATPase subunit  interface; other site
1126011006444	dimer interface [polypeptide binding]; other site
1126011006445	putative PBP binding regions; other site
1126011006446	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1126011006447	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1126011006448	putative ligand binding residues [chemical binding]; other site
1126011006449	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1126011006450	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1126011006451	Walker A/P-loop; other site
1126011006452	ATP binding site [chemical binding]; other site
1126011006453	Q-loop/lid; other site
1126011006454	ABC transporter signature motif; other site
1126011006455	Walker B; other site
1126011006456	D-loop; other site
1126011006457	H-loop/switch region; other site
1126011006458	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1126011006459	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011006460	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011006461	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011006462	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1126011006463	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1126011006464	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011006465	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011006466	Walker A/P-loop; other site
1126011006467	ATP binding site [chemical binding]; other site
1126011006468	Q-loop/lid; other site
1126011006469	ABC transporter signature motif; other site
1126011006470	Walker B; other site
1126011006471	D-loop; other site
1126011006472	H-loop/switch region; other site
1126011006473	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1126011006474	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1126011006475	dimer interface [polypeptide binding]; other site
1126011006476	ADP-ribose binding site [chemical binding]; other site
1126011006477	active site
1126011006478	nudix motif; other site
1126011006479	metal binding site [ion binding]; metal-binding site
1126011006480	5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only]; Region: XpaC; COG4915
1126011006481	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1126011006482	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1126011006483	active site
1126011006484	DNA polymerase IV; Validated; Region: PRK02406
1126011006485	DNA binding site [nucleotide binding]
1126011006486	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1126011006487	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1126011006488	NAD(P) binding site [chemical binding]; other site
1126011006489	active site
1126011006490	ribonuclease Z; Region: RNase_Z; TIGR02651
1126011006491	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1126011006492	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1126011006493	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1126011006494	Protein of unknown function (DUF1694); Region: DUF1694; cl02318
1126011006495	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1126011006496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011006497	Coenzyme A binding pocket [chemical binding]; other site
1126011006498	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1126011006499	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1126011006500	acetolactate synthase catalytic subunit; Reviewed; Region: PRK07710
1126011006501	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1126011006502	PYR/PP interface [polypeptide binding]; other site
1126011006503	dimer interface [polypeptide binding]; other site
1126011006504	TPP binding site [chemical binding]; other site
1126011006505	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1126011006506	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1126011006507	TPP-binding site [chemical binding]; other site
1126011006508	dimer interface [polypeptide binding]; other site
1126011006509	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1126011006510	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1126011006511	putative valine binding site [chemical binding]; other site
1126011006512	dimer interface [polypeptide binding]; other site
1126011006513	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1126011006514	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1126011006515	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1126011006516	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1126011006517	2-isopropylmalate synthase; Validated; Region: PRK00915
1126011006518	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1126011006519	active site
1126011006520	catalytic residues [active]
1126011006521	metal binding site [ion binding]; metal-binding site
1126011006522	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1126011006523	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1126011006524	tartrate dehydrogenase; Region: TTC; TIGR02089
1126011006525	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1126011006526	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1126011006527	substrate binding site [chemical binding]; other site
1126011006528	ligand binding site [chemical binding]; other site
1126011006529	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1126011006530	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1126011006531	substrate binding site [chemical binding]; other site
1126011006532	threonine dehydratase; Validated; Region: PRK08639
1126011006533	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1126011006534	tetramer interface [polypeptide binding]; other site
1126011006535	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011006536	catalytic residue [active]
1126011006537	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1126011006538	alpha-acetolactate decarboxylase; Region: acetolac_decarb; TIGR01252
1126011006539	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
1126011006540	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1126011006541	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1126011006542	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1126011006543	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011006544	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011006545	DNA binding site [nucleotide binding]
1126011006546	domain linker motif; other site
1126011006547	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1126011006548	dimerization interface [polypeptide binding]; other site
1126011006549	ligand binding site [chemical binding]; other site
1126011006550	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1126011006551	intersubunit interface [polypeptide binding]; other site
1126011006552	active site
1126011006553	catalytic residue [active]
1126011006554	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1126011006555	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1126011006556	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1126011006557	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1126011006558	active pocket/dimerization site; other site
1126011006559	active site
1126011006560	phosphorylation site [posttranslational modification]
1126011006561	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1126011006562	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1126011006563	putative active site [active]
1126011006564	SIS domain; Region: SIS; pfam01380
1126011006565	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1126011006566	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1126011006567	dimer interface [polypeptide binding]; other site
1126011006568	active site
1126011006569	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1126011006570	dimer interface [polypeptide binding]; other site
1126011006571	active site
1126011006572	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1126011006573	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1126011006574	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1126011006575	active site
1126011006576	phosphorylation site [posttranslational modification]
1126011006577	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011006578	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011006579	DNA-binding site [nucleotide binding]; DNA binding site
1126011006580	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1126011006581	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011006582	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011006583	DNA-binding site [nucleotide binding]; DNA binding site
1126011006584	UTRA domain; Region: UTRA; pfam07702
1126011006585	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011006586	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011006587	active site
1126011006588	catalytic tetrad [active]
1126011006589	acetolactate synthase; Reviewed; Region: PRK08617
1126011006590	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1126011006591	PYR/PP interface [polypeptide binding]; other site
1126011006592	dimer interface [polypeptide binding]; other site
1126011006593	TPP binding site [chemical binding]; other site
1126011006594	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1126011006595	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1126011006596	TPP-binding site [chemical binding]; other site
1126011006597	dimer interface [polypeptide binding]; other site
1126011006598	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011006599	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1126011006600	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1126011006601	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011006602	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011006603	dimer interface [polypeptide binding]; other site
1126011006604	conserved gate region; other site
1126011006605	ABC-ATPase subunit interface; other site
1126011006606	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1126011006607	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011006608	dimer interface [polypeptide binding]; other site
1126011006609	conserved gate region; other site
1126011006610	ABC-ATPase subunit interface; other site
1126011006611	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
1126011006612	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011006613	active site
1126011006614	phosphorylation site [posttranslational modification]
1126011006615	intermolecular recognition site; other site
1126011006616	dimerization interface [polypeptide binding]; other site
1126011006617	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011006618	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1126011006619	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1126011006620	dimerization interface [polypeptide binding]; other site
1126011006621	Histidine kinase; Region: His_kinase; pfam06580
1126011006622	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011006623	ATP binding site [chemical binding]; other site
1126011006624	Mg2+ binding site [ion binding]; other site
1126011006625	G-X-G motif; other site
1126011006626	Predicted integral membrane protein [Function unknown]; Region: COG5578
1126011006627	Uncharacterized conserved protein [Function unknown]; Region: COG3538
1126011006628	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
1126011006629	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
1126011006630	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
1126011006631	active site
1126011006632	metal binding site [ion binding]; metal-binding site
1126011006633	homodimer interface [polypeptide binding]; other site
1126011006634	catalytic site [active]
1126011006635	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1126011006636	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
1126011006637	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
1126011006638	active site
1126011006639	catalytic site [active]
1126011006640	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1126011006641	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1126011006642	DNA-binding site [nucleotide binding]; DNA binding site
1126011006643	RNA-binding motif; other site
1126011006644	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1126011006645	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1126011006646	active site
1126011006647	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1126011006648	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1126011006649	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1126011006650	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1126011006651	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1126011006652	active site
1126011006653	HIGH motif; other site
1126011006654	nucleotide binding site [chemical binding]; other site
1126011006655	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1126011006656	active site
1126011006657	KMSKS motif; other site
1126011006658	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1126011006659	tRNA binding surface [nucleotide binding]; other site
1126011006660	anticodon binding site; other site
1126011006661	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1126011006662	DivIVA protein; Region: DivIVA; pfam05103
1126011006663	DivIVA domain; Region: DivI1A_domain; TIGR03544
1126011006664	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1126011006665	HTH domain; Region: HTH_11; pfam08279
1126011006666	3H domain; Region: 3H; pfam02829
1126011006667	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1126011006668	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1126011006669	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011006670	catalytic residue [active]
1126011006671	L-aspartate oxidase; Provisional; Region: PRK08071
1126011006672	L-aspartate oxidase; Provisional; Region: PRK06175
1126011006673	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1126011006674	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK08072
1126011006675	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1126011006676	dimerization interface [polypeptide binding]; other site
1126011006677	active site
1126011006678	quinolinate synthetase; Provisional; Region: PRK09375
1126011006679	potential frameshift: common BLAST hit: gi|226223088|ref|YP_002757195.1| membrane associated lipoprotein
1126011006680	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1126011006681	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006682	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006683	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1126011006684	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006685	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006686	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006687	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006688	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1126011006689	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
1126011006690	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011006691	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1126011006692	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011006693	S-adenosylmethionine binding site [chemical binding]; other site
1126011006694	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011006695	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011006696	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1126011006697	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011006698	RNA binding surface [nucleotide binding]; other site
1126011006699	YGGT family; Region: YGGT; pfam02325
1126011006700	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
1126011006701	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1126011006702	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1126011006703	catalytic residue [active]
1126011006704	cell division protein FtsZ; Validated; Region: PRK09330
1126011006705	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1126011006706	nucleotide binding site [chemical binding]; other site
1126011006707	SulA interaction site; other site
1126011006708	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
1126011006709	Cell division protein FtsA; Region: FtsA; smart00842
1126011006710	Cell division protein FtsA; Region: FtsA; pfam14450
1126011006711	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1126011006712	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1126011006713	Cell division protein FtsQ; Region: FtsQ; pfam03799
1126011006714	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1126011006715	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1126011006716	active site
1126011006717	homodimer interface [polypeptide binding]; other site
1126011006718	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1126011006719	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1126011006720	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1126011006721	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1126011006722	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1126011006723	Mg++ binding site [ion binding]; other site
1126011006724	putative catalytic motif [active]
1126011006725	putative substrate binding site [chemical binding]; other site
1126011006726	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1126011006727	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1126011006728	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1126011006729	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1126011006730	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1126011006731	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1126011006732	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1126011006733	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1126011006734	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1126011006735	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
1126011006736	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
1126011006737	MraW methylase family; Region: Methyltransf_5; pfam01795
1126011006738	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1126011006739	MraZ protein; Region: MraZ; pfam02381
1126011006740	MraZ protein; Region: MraZ; pfam02381
1126011006741	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011006742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011006743	putative substrate translocation pore; other site
1126011006744	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1126011006745	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1126011006746	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1126011006747	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
1126011006748	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1126011006749	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1126011006750	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1126011006751	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1126011006752	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
1126011006753	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; pfam05636
1126011006754	hypothetical protein; Provisional; Region: PRK13670
1126011006755	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1126011006756	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1126011006757	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
1126011006758	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011006759	Walker A/P-loop; other site
1126011006760	ATP binding site [chemical binding]; other site
1126011006761	Q-loop/lid; other site
1126011006762	ABC transporter signature motif; other site
1126011006763	Walker B; other site
1126011006764	D-loop; other site
1126011006765	H-loop/switch region; other site
1126011006766	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
1126011006767	PDZ domain of ATP-dependent LON serine proteases. Most PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. In this bacterial subfamily of protease-associated PDZ...; Region: PDZ_LON_protease; cd00986
1126011006768	protein binding site [polypeptide binding]; other site
1126011006769	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1126011006770	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1126011006771	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1126011006772	active site
1126011006773	(T/H)XGH motif; other site
1126011006774	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1126011006775	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011006776	S-adenosylmethionine binding site [chemical binding]; other site
1126011006777	hypothetical protein; Provisional; Region: PRK02886
1126011006778	Regulatory protein involved in competence development and sporulation [Replication, recombination and repair;    Signal transduction mechanisms]; Region: COG3679
1126011006779	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1126011006780	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1126011006781	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1126011006782	UbiA prenyltransferase family; Region: UbiA; pfam01040
1126011006783	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1126011006784	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1126011006785	Ion transport protein; Region: Ion_trans; pfam00520
1126011006786	Ion channel; Region: Ion_trans_2; pfam07885
1126011006787	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
1126011006788	MOSC domain; Region: MOSC; pfam03473
1126011006789	3-alpha domain; Region: 3-alpha; pfam03475
1126011006790	Reeler-like domain of YcnI and similar proteins; Region: YcnI_like; cd08545
1126011006791	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
1126011006792	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1126011006793	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13953
1126011006794	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1126011006795	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1126011006796	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1126011006797	active site
1126011006798	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1126011006799	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1126011006800	ring oligomerisation interface [polypeptide binding]; other site
1126011006801	ATP/Mg binding site [chemical binding]; other site
1126011006802	stacking interactions; other site
1126011006803	hinge regions; other site
1126011006804	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1126011006805	oligomerisation interface [polypeptide binding]; other site
1126011006806	mobile loop; other site
1126011006807	roof hairpin; other site
1126011006808	CAAX protease self-immunity; Region: Abi; pfam02517
1126011006809	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1126011006810	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1126011006811	CoA binding domain; Region: CoA_binding; pfam02629
1126011006812	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1126011006813	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011006814	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011006815	ABC transporter; Region: ABC_tran_2; pfam12848
1126011006816	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011006817	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011006818	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1126011006819	UGMP family protein; Validated; Region: PRK09604
1126011006820	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1126011006821	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1126011006822	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011006823	Coenzyme A binding pocket [chemical binding]; other site
1126011006824	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1126011006825	Glycoprotease family; Region: Peptidase_M22; pfam00814
1126011006826	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1126011006827	camphor resistance protein CrcB; Provisional; Region: PRK14214
1126011006828	camphor resistance protein CrcB; Provisional; Region: PRK14231
1126011006829	Uncharacterized conserved protein [Function unknown]; Region: COG4832
1126011006830	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1126011006831	Phosphotransferase enzyme family; Region: APH; pfam01636
1126011006832	active site
1126011006833	substrate binding site [chemical binding]; other site
1126011006834	ATP binding site [chemical binding]; other site
1126011006835	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011006836	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011006837	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011006838	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011006839	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011006840	non-specific DNA binding site [nucleotide binding]; other site
1126011006841	salt bridge; other site
1126011006842	sequence-specific DNA binding site [nucleotide binding]; other site
1126011006843	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1126011006844	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1126011006845	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011006846	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011006847	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1126011006848	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1126011006849	substrate binding pocket [chemical binding]; other site
1126011006850	argininosuccinate synthase; Provisional; Region: PRK13820
1126011006851	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1126011006852	ANP binding site [chemical binding]; other site
1126011006853	Substrate Binding Site II [chemical binding]; other site
1126011006854	Substrate Binding Site I [chemical binding]; other site
1126011006855	argininosuccinate lyase; Provisional; Region: PRK00855
1126011006856	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1126011006857	active sites [active]
1126011006858	tetramer interface [polypeptide binding]; other site
1126011006859	BCCT family transporter; Region: BCCT; pfam02028
1126011006860	hypothetical protein; Provisional; Region: PRK06357
1126011006861	active site
1126011006862	intersubunit interface [polypeptide binding]; other site
1126011006863	Zn2+ binding site [ion binding]; other site
1126011006864	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1126011006865	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1126011006866	putative substrate binding site [chemical binding]; other site
1126011006867	putative ATP binding site [chemical binding]; other site
1126011006868	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1126011006869	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1126011006870	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1126011006871	active site
1126011006872	P-loop; other site
1126011006873	phosphorylation site [posttranslational modification]
1126011006874	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011006875	active site
1126011006876	phosphorylation site [posttranslational modification]
1126011006877	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011006878	PRD domain; Region: PRD; pfam00874
1126011006879	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011006880	active site
1126011006881	P-loop; other site
1126011006882	phosphorylation site [posttranslational modification]
1126011006883	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: PtsN; COG1762
1126011006884	active site
1126011006885	phosphorylation site [posttranslational modification]
1126011006886	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1126011006887	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011006888	DNA-binding site [nucleotide binding]; DNA binding site
1126011006889	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011006890	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011006891	homodimer interface [polypeptide binding]; other site
1126011006892	catalytic residue [active]
1126011006893	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1126011006894	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1126011006895	active site
1126011006896	multimer interface [polypeptide binding]; other site
1126011006897	glutamine amidotransferase subunit PdxT; Provisional; Region: PRK13525
1126011006898	conserved cys residue [active]
1126011006899	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1126011006900	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1126011006901	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1126011006902	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1126011006903	G1 box; other site
1126011006904	GTP/Mg2+ binding site [chemical binding]; other site
1126011006905	Switch I region; other site
1126011006906	G2 box; other site
1126011006907	G3 box; other site
1126011006908	Switch II region; other site
1126011006909	G4 box; other site
1126011006910	G5 box; other site
1126011006911	Nucleoside recognition; Region: Gate; pfam07670
1126011006912	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1126011006913	Nucleoside recognition; Region: Gate; pfam07670
1126011006914	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1126011006915	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1126011006916	putative active site [active]
1126011006917	putative metal binding site [ion binding]; other site
1126011006918	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011006919	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1126011006920	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011006921	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1126011006922	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1126011006923	active site
1126011006924	dimer interface [polypeptide binding]; other site
1126011006925	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1126011006926	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1126011006927	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1126011006928	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1126011006929	dimer interface [polypeptide binding]; other site
1126011006930	FMN binding site [chemical binding]; other site
1126011006931	NADPH bind site [chemical binding]; other site
1126011006932	Helix-turn-helix domain; Region: HTH_17; pfam12728
1126011006933	putative heme peroxidase; Provisional; Region: PRK12276
1126011006934	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011006935	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011006936	Walker A/P-loop; other site
1126011006937	ATP binding site [chemical binding]; other site
1126011006938	Q-loop/lid; other site
1126011006939	ABC transporter signature motif; other site
1126011006940	Walker B; other site
1126011006941	D-loop; other site
1126011006942	H-loop/switch region; other site
1126011006943	FtsX-like permease family; Region: FtsX; pfam02687
1126011006944	FtsX-like permease family; Region: FtsX; pfam02687
1126011006945	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011006946	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011006947	Coenzyme A binding pocket [chemical binding]; other site
1126011006948	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1126011006949	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1126011006950	active site
1126011006951	substrate binding site [chemical binding]; other site
1126011006952	metal binding site [ion binding]; metal-binding site
1126011006953	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1126011006954	YbbR-like protein; Region: YbbR; pfam07949
1126011006955	YbbR-like protein; Region: YbbR; pfam07949
1126011006956	YbbR-like protein; Region: YbbR; pfam07949
1126011006957	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1126011006958	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1126011006959	maltose phosphorylase; Provisional; Region: PRK13807
1126011006960	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1126011006961	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1126011006962	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1126011006963	Predicted integral membrane protein [Function unknown]; Region: COG5521
1126011006964	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011006965	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011006966	dimer interface [polypeptide binding]; other site
1126011006967	conserved gate region; other site
1126011006968	putative PBP binding loops; other site
1126011006969	ABC-ATPase subunit interface; other site
1126011006970	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011006971	dimer interface [polypeptide binding]; other site
1126011006972	conserved gate region; other site
1126011006973	putative PBP binding loops; other site
1126011006974	ABC-ATPase subunit interface; other site
1126011006975	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1126011006976	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011006977	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1126011006978	homodimer interface [polypeptide binding]; other site
1126011006979	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1126011006980	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1126011006981	active site
1126011006982	homodimer interface [polypeptide binding]; other site
1126011006983	catalytic site [active]
1126011006984	CAAX protease self-immunity; Region: Abi; cl00558
1126011006985	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011006986	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011006987	DNA binding site [nucleotide binding]
1126011006988	domain linker motif; other site
1126011006989	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1126011006990	ligand binding site [chemical binding]; other site
1126011006991	dimerization interface [polypeptide binding]; other site
1126011006992	Amino acid permease; Region: AA_permease_2; pfam13520
1126011006993	K+ potassium transporter; Region: K_trans; cl15781
1126011006994	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011006995	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011006996	ligand binding site [chemical binding]; other site
1126011006997	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011006998	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011006999	ligand binding site [chemical binding]; other site
1126011007000	flexible hinge region; other site
1126011007001	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011007002	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1126011007003	intersubunit interface [polypeptide binding]; other site
1126011007004	active site
1126011007005	zinc binding site [ion binding]; other site
1126011007006	Na+ binding site [ion binding]; other site
1126011007007	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1126011007008	intersubunit interface [polypeptide binding]; other site
1126011007009	active site
1126011007010	zinc binding site [ion binding]; other site
1126011007011	Na+ binding site [ion binding]; other site
1126011007012	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011007013	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011007014	active site
1126011007015	P-loop; other site
1126011007016	phosphorylation site [posttranslational modification]
1126011007017	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011007018	active site
1126011007019	phosphorylation site [posttranslational modification]
1126011007020	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011007021	HTH domain; Region: HTH_11; pfam08279
1126011007022	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011007023	PRD domain; Region: PRD; pfam00874
1126011007024	PRD domain; Region: PRD; pfam00874
1126011007025	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011007026	active site
1126011007027	P-loop; other site
1126011007028	phosphorylation site [posttranslational modification]
1126011007029	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1126011007030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011007031	Walker A/P-loop; other site
1126011007032	ATP binding site [chemical binding]; other site
1126011007033	Q-loop/lid; other site
1126011007034	ABC transporter signature motif; other site
1126011007035	Walker B; other site
1126011007036	D-loop; other site
1126011007037	H-loop/switch region; other site
1126011007038	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1126011007039	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1126011007040	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1126011007041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011007042	Coenzyme A binding pocket [chemical binding]; other site
1126011007043	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1126011007044	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1126011007045	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1126011007046	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1126011007047	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011007048	DNA-binding site [nucleotide binding]; DNA binding site
1126011007049	UTRA domain; Region: UTRA; pfam07702
1126011007050	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1126011007051	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1126011007052	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011007053	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011007054	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1126011007055	putative dimerization interface [polypeptide binding]; other site
1126011007056	Predicted membrane protein [Function unknown]; Region: COG2855
1126011007057	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
1126011007058	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
1126011007059	putative metal binding site [ion binding]; other site
1126011007060	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
1126011007061	homodimer interface [polypeptide binding]; other site
1126011007062	chemical substrate binding site [chemical binding]; other site
1126011007063	oligomer interface [polypeptide binding]; other site
1126011007064	metal binding site [ion binding]; metal-binding site
1126011007065	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011007066	catalytic residues [active]
1126011007067	flavodoxin; Provisional; Region: PRK09271
1126011007068	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1126011007069	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1126011007070	dimer interface [polypeptide binding]; other site
1126011007071	putative radical transfer pathway; other site
1126011007072	diiron center [ion binding]; other site
1126011007073	tyrosyl radical; other site
1126011007074	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09209
1126011007075	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1126011007076	active site
1126011007077	dimer interface [polypeptide binding]; other site
1126011007078	catalytic residues [active]
1126011007079	effector binding site; other site
1126011007080	R2 peptide binding site; other site
1126011007081	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
1126011007082	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1126011007083	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1126011007084	SCP-2 sterol transfer family; Region: SCP2; cl01225
1126011007085	CsbD-like; Region: CsbD; cl17424
1126011007086	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011007087	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011007088	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1126011007089	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1126011007090	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1126011007091	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1126011007092	conserved cys residue [active]
1126011007093	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1126011007094	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011007095	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011007096	Cupin; Region: Cupin_1; pfam00190
1126011007097	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011007098	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011007099	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011007100	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011007101	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011007102	ligand binding site [chemical binding]; other site
1126011007103	flexible hinge region; other site
1126011007104	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1126011007105	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1126011007106	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011007107	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1126011007108	dimer interface [polypeptide binding]; other site
1126011007109	active site
1126011007110	metal binding site [ion binding]; metal-binding site
1126011007111	glutathione binding site [chemical binding]; other site
1126011007112	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1126011007113	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1126011007114	FMN binding site [chemical binding]; other site
1126011007115	substrate binding site [chemical binding]; other site
1126011007116	putative catalytic residue [active]
1126011007117	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1126011007118	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1126011007119	Coenzyme A transferase; Region: CoA_trans; smart00882
1126011007120	Coenzyme A transferase; Region: CoA_trans; cl17247
1126011007121	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011007122	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1126011007123	Walker A motif; other site
1126011007124	ATP binding site [chemical binding]; other site
1126011007125	Walker B motif; other site
1126011007126	arginine finger; other site
1126011007127	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1126011007128	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1126011007129	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1126011007130	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1126011007131	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1126011007132	metal binding site [ion binding]; metal-binding site
1126011007133	active site
1126011007134	I-site; other site
1126011007135	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1126011007136	classical (c) SDRs; Region: SDR_c; cd05233
1126011007137	NAD(P) binding site [chemical binding]; other site
1126011007138	active site
1126011007139	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1126011007140	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011007141	Tic20-like protein; Region: Tic20; pfam09685
1126011007142	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007143	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007144	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011007145	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1126011007146	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007147	Collagen binding domain; Region: Collagen_bind; pfam05737
1126011007148	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007149	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007150	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007151	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1126011007152	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007153	Collagen binding domain; Region: Collagen_bind; pfam05737
1126011007154	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007155	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007156	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007157	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007158	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007159	Cna protein B-type domain; Region: Cna_B; pfam05738
1126011007160	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007161	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011007162	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007163	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007164	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011007165	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
1126011007166	Sortase B (SrtB) or subfamily-2 sortases are membrane cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_B_2; cd05826
1126011007167	active site
1126011007168	catalytic site [active]
1126011007169	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1126011007170	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1126011007171	Walker A/P-loop; other site
1126011007172	ATP binding site [chemical binding]; other site
1126011007173	Q-loop/lid; other site
1126011007174	ABC transporter signature motif; other site
1126011007175	Walker B; other site
1126011007176	D-loop; other site
1126011007177	H-loop/switch region; other site
1126011007178	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1126011007179	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011007180	ABC-ATPase subunit  interface; other site
1126011007181	dimer interface [polypeptide binding]; other site
1126011007182	putative PBP binding regions; other site
1126011007183	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
1126011007184	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1126011007185	intersubunit interface [polypeptide binding]; other site
1126011007186	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1126011007187	heme-binding site [chemical binding]; other site
1126011007188	Cell surface protein [Cell envelope biogenesis, outer membrane]; Region: COG5386
1126011007189	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1126011007190	heme-binding site [chemical binding]; other site
1126011007191	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1126011007192	heme-binding site [chemical binding]; other site
1126011007193	sortase B cell surface sorting signal; Region: srtB_target; TIGR03063
1126011007194	heme uptake protein IsdC; Region: IsdC; TIGR03656
1126011007195	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
1126011007196	heme-binding site [chemical binding]; other site
1126011007197	sortase B cell surface sorting signal; Region: srtB_target; TIGR03063
1126011007198	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
1126011007199	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
1126011007200	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1126011007201	active site
1126011007202	Zn binding site [ion binding]; other site
1126011007203	Competence protein CoiA-like family; Region: CoiA; cl11541
1126011007204	Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion]; Region: MecA; COG4862
1126011007205	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1126011007206	ArsC family; Region: ArsC; pfam03960
1126011007207	putative catalytic residues [active]
1126011007208	thiol/disulfide switch; other site
1126011007209	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1126011007210	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1126011007211	Walker A/P-loop; other site
1126011007212	ATP binding site [chemical binding]; other site
1126011007213	Q-loop/lid; other site
1126011007214	ABC transporter signature motif; other site
1126011007215	Walker B; other site
1126011007216	D-loop; other site
1126011007217	H-loop/switch region; other site
1126011007218	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1126011007219	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1126011007220	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1126011007221	Walker A/P-loop; other site
1126011007222	ATP binding site [chemical binding]; other site
1126011007223	Q-loop/lid; other site
1126011007224	ABC transporter signature motif; other site
1126011007225	Walker B; other site
1126011007226	D-loop; other site
1126011007227	H-loop/switch region; other site
1126011007228	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1126011007229	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1126011007230	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007231	dimer interface [polypeptide binding]; other site
1126011007232	conserved gate region; other site
1126011007233	putative PBP binding loops; other site
1126011007234	ABC-ATPase subunit interface; other site
1126011007235	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1126011007236	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007237	dimer interface [polypeptide binding]; other site
1126011007238	conserved gate region; other site
1126011007239	putative PBP binding loops; other site
1126011007240	ABC-ATPase subunit interface; other site
1126011007241	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1126011007242	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1126011007243	peptide binding site [polypeptide binding]; other site
1126011007244	Domain of unknown function (DUF3899); Region: DUF3899; pfam13038
1126011007245	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1126011007246	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1126011007247	active site
1126011007248	HIGH motif; other site
1126011007249	dimer interface [polypeptide binding]; other site
1126011007250	KMSKS motif; other site
1126011007251	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1126011007252	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011007253	MarR family; Region: MarR; pfam01047
1126011007254	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1126011007255	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1126011007256	dimer interface [polypeptide binding]; other site
1126011007257	active site
1126011007258	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1126011007259	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1126011007260	dimer interface [polypeptide binding]; other site
1126011007261	active site
1126011007262	CoA binding pocket [chemical binding]; other site
1126011007263	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011007264	SH3-like domain; Region: SH3_8; pfam13457
1126011007265	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
1126011007266	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011007267	catalytic core [active]
1126011007268	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1126011007269	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1126011007270	Clp amino terminal domain; Region: Clp_N; pfam02861
1126011007271	Clp amino terminal domain; Region: Clp_N; pfam02861
1126011007272	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011007273	Walker A motif; other site
1126011007274	ATP binding site [chemical binding]; other site
1126011007275	Walker B motif; other site
1126011007276	arginine finger; other site
1126011007277	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011007278	Walker A motif; other site
1126011007279	ATP binding site [chemical binding]; other site
1126011007280	Walker B motif; other site
1126011007281	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1126011007282	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1126011007283	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1126011007284	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011007285	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007286	active site
1126011007287	motif I; other site
1126011007288	motif II; other site
1126011007289	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1126011007290	Predicted acetyltransferase [General function prediction only]; Region: COG3393
1126011007291	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1126011007292	ferrochelatase; Provisional; Region: PRK12435
1126011007293	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1126011007294	C-terminal domain interface [polypeptide binding]; other site
1126011007295	active site
1126011007296	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1126011007297	active site
1126011007298	N-terminal domain interface [polypeptide binding]; other site
1126011007299	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1126011007300	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1126011007301	substrate binding site [chemical binding]; other site
1126011007302	active site
1126011007303	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1126011007304	Predicted ABC-type exoprotein transport system, permease component [Intracellular trafficking and secretion]; Region: EcsB; COG4473
1126011007305	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1126011007306	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011007307	Walker A/P-loop; other site
1126011007308	ATP binding site [chemical binding]; other site
1126011007309	Q-loop/lid; other site
1126011007310	ABC transporter signature motif; other site
1126011007311	Walker B; other site
1126011007312	D-loop; other site
1126011007313	H-loop/switch region; other site
1126011007314	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
1126011007315	HIT family signature motif; other site
1126011007316	catalytic residue [active]
1126011007317	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
1126011007318	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
1126011007319	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1126011007320	SurA N-terminal domain; Region: SurA_N_3; cl07813
1126011007321	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1126011007322	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1126011007323	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1126011007324	generic binding surface II; other site
1126011007325	generic binding surface I; other site
1126011007326	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011007327	Zn2+ binding site [ion binding]; other site
1126011007328	Mg2+ binding site [ion binding]; other site
1126011007329	Uncharacterized conserved protein [Function unknown]; Region: COG4717
1126011007330	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1126011007331	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1126011007332	active site
1126011007333	metal binding site [ion binding]; metal-binding site
1126011007334	DNA binding site [nucleotide binding]
1126011007335	hypothetical protein; Provisional; Region: PRK13676
1126011007336	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
1126011007337	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1126011007338	Class II fumarases; Region: Fumarase_classII; cd01362
1126011007339	active site
1126011007340	tetramer interface [polypeptide binding]; other site
1126011007341	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1126011007342	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011007343	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011007344	Walker A/P-loop; other site
1126011007345	ATP binding site [chemical binding]; other site
1126011007346	Q-loop/lid; other site
1126011007347	ABC transporter signature motif; other site
1126011007348	Walker B; other site
1126011007349	D-loop; other site
1126011007350	H-loop/switch region; other site
1126011007351	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1126011007352	Transglycosylase; Region: Transgly; pfam00912
1126011007353	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1126011007354	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1126011007355	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1126011007356	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1126011007357	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1126011007358	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1126011007359	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1126011007360	Domain of unknown function DUF21; Region: DUF21; pfam01595
1126011007361	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1126011007362	Transporter associated domain; Region: CorC_HlyC; smart01091
1126011007363	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011007364	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011007365	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1126011007366	putative dimerization interface [polypeptide binding]; other site
1126011007367	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1126011007368	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
1126011007369	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1126011007370	active site
1126011007371	FMN binding site [chemical binding]; other site
1126011007372	substrate binding site [chemical binding]; other site
1126011007373	putative catalytic residue [active]
1126011007374	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011007375	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011007376	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1126011007377	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1126011007378	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1126011007379	shikimate binding site; other site
1126011007380	NAD(P) binding site [chemical binding]; other site
1126011007381	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011007382	putative substrate translocation pore; other site
1126011007383	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011007384	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011007385	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011007386	putative substrate translocation pore; other site
1126011007387	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1126011007388	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011007389	Walker A/P-loop; other site
1126011007390	ATP binding site [chemical binding]; other site
1126011007391	Q-loop/lid; other site
1126011007392	ABC transporter signature motif; other site
1126011007393	Walker B; other site
1126011007394	D-loop; other site
1126011007395	H-loop/switch region; other site
1126011007396	Predicted transcriptional regulators [Transcription]; Region: COG1725
1126011007397	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1126011007398	DNA-binding site [nucleotide binding]; DNA binding site
1126011007399	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1126011007400	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1126011007401	DNA binding site [nucleotide binding]
1126011007402	active site
1126011007403	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1126011007404	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1126011007405	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011007406	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011007407	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1126011007408	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1126011007409	active site
1126011007410	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_6; cd07242
1126011007411	putative dimer interface [polypeptide binding]; other site
1126011007412	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011007413	ligand binding site [chemical binding]; other site
1126011007414	Zn binding site [ion binding]; other site
1126011007415	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1126011007416	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
1126011007417	active site
1126011007418	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011007419	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011007420	active site
1126011007421	catalytic tetrad [active]
1126011007422	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1126011007423	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1126011007424	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1126011007425	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1126011007426	substrate binding pocket [chemical binding]; other site
1126011007427	membrane-bound complex binding site; other site
1126011007428	hinge residues; other site
1126011007429	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1126011007430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007431	dimer interface [polypeptide binding]; other site
1126011007432	conserved gate region; other site
1126011007433	putative PBP binding loops; other site
1126011007434	ABC-ATPase subunit interface; other site
1126011007435	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1126011007436	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1126011007437	Walker A/P-loop; other site
1126011007438	ATP binding site [chemical binding]; other site
1126011007439	Q-loop/lid; other site
1126011007440	ABC transporter signature motif; other site
1126011007441	Walker B; other site
1126011007442	D-loop; other site
1126011007443	H-loop/switch region; other site
1126011007444	aspartate aminotransferase; Provisional; Region: PRK06348
1126011007445	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011007446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011007447	homodimer interface [polypeptide binding]; other site
1126011007448	catalytic residue [active]
1126011007449	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1126011007450	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1126011007451	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007452	motif II; other site
1126011007453	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1126011007454	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1126011007455	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1126011007456	proposed catalytic triad [active]
1126011007457	conserved cys residue [active]
1126011007458	basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins; Region: B_zip1; cl02576
1126011007459	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011007460	methionine cluster; other site
1126011007461	active site
1126011007462	phosphorylation site [posttranslational modification]
1126011007463	metal binding site [ion binding]; metal-binding site
1126011007464	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011007465	Coenzyme A binding pocket [chemical binding]; other site
1126011007466	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011007467	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1126011007468	esterase; Provisional; Region: PRK10566
1126011007469	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1126011007470	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011007471	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1126011007472	motif II; other site
1126011007473	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007474	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1126011007475	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011007476	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011007477	hypothetical protein; Provisional; Region: PRK13673
1126011007478	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1126011007479	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1126011007480	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1126011007481	Part of AAA domain; Region: AAA_19; pfam13245
1126011007482	Family description; Region: UvrD_C_2; pfam13538
1126011007483	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1126011007484	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1126011007485	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1126011007486	IDEAL domain; Region: IDEAL; pfam08858
1126011007487	ComK protein; Region: ComK; cl11560
1126011007488	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1126011007489	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011007490	non-specific DNA binding site [nucleotide binding]; other site
1126011007491	salt bridge; other site
1126011007492	sequence-specific DNA binding site [nucleotide binding]; other site
1126011007493	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1126011007494	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011007495	active site
1126011007496	phosphorylation site [posttranslational modification]
1126011007497	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011007498	active site
1126011007499	P-loop; other site
1126011007500	phosphorylation site [posttranslational modification]
1126011007501	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011007502	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1126011007503	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1126011007504	putative substrate binding site [chemical binding]; other site
1126011007505	putative ATP binding site [chemical binding]; other site
1126011007506	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011007507	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1126011007508	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011007509	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1126011007510	trimer interface [polypeptide binding]; other site
1126011007511	active site
1126011007512	G bulge; other site
1126011007513	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1126011007514	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1126011007515	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1126011007516	non-specific DNA interactions [nucleotide binding]; other site
1126011007517	DNA binding site [nucleotide binding]
1126011007518	sequence specific DNA binding site [nucleotide binding]; other site
1126011007519	putative cAMP binding site [chemical binding]; other site
1126011007520	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1126011007521	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1126011007522	substrate binding site [chemical binding]; other site
1126011007523	ATP binding site [chemical binding]; other site
1126011007524	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1126011007525	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1126011007526	RNA binding surface [nucleotide binding]; other site
1126011007527	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1126011007528	active site
1126011007529	uracil binding [chemical binding]; other site
1126011007530	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1126011007531	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1126011007532	active site
1126011007533	non-prolyl cis peptide bond; other site
1126011007534	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1126011007535	catalytic residues [active]
1126011007536	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1126011007537	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1126011007538	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1126011007539	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1126011007540	Walker A/P-loop; other site
1126011007541	ATP binding site [chemical binding]; other site
1126011007542	Q-loop/lid; other site
1126011007543	ABC transporter signature motif; other site
1126011007544	Walker B; other site
1126011007545	D-loop; other site
1126011007546	H-loop/switch region; other site
1126011007547	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1126011007548	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007549	dimer interface [polypeptide binding]; other site
1126011007550	conserved gate region; other site
1126011007551	putative PBP binding loops; other site
1126011007552	ABC-ATPase subunit interface; other site
1126011007553	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1126011007554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007555	dimer interface [polypeptide binding]; other site
1126011007556	conserved gate region; other site
1126011007557	putative PBP binding loops; other site
1126011007558	ABC-ATPase subunit interface; other site
1126011007559	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1126011007560	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1126011007561	substrate binding pocket [chemical binding]; other site
1126011007562	membrane-bound complex binding site; other site
1126011007563	hinge residues; other site
1126011007564	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011007565	Coenzyme A binding pocket [chemical binding]; other site
1126011007566	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1126011007567	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1126011007568	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1126011007569	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1126011007570	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1126011007571	dimerization interface [polypeptide binding]; other site
1126011007572	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1126011007573	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1126011007574	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1126011007575	active site
1126011007576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011007577	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011007578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011007579	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
1126011007580	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1126011007581	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1126011007582	active site
1126011007583	trimer interface [polypeptide binding]; other site
1126011007584	allosteric site; other site
1126011007585	active site lid [active]
1126011007586	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1126011007587	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011007588	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1126011007589	Predicted membrane protein [Function unknown]; Region: COG1511
1126011007590	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1126011007591	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
1126011007592	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1126011007593	Predicted transcriptional regulator [Transcription]; Region: COG1959
1126011007594	Transcriptional regulator; Region: Rrf2; pfam02082
1126011007595	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
1126011007596	L-tyrosine decarboxylase; Provisional; Region: PRK13520
1126011007597	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1126011007598	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011007599	catalytic residue [active]
1126011007600	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
1126011007601	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011007602	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
1126011007603	potential protein location (hypothetical protein MUO_11810 [Listeria monocytogenes 07PF0776]) that overlaps RNA (tRNA-F)
1126011007604	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1126011007605	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1126011007606	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1126011007607	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1126011007608	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1126011007609	active site
1126011007610	dimer interface [polypeptide binding]; other site
1126011007611	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1126011007612	dimer interface [polypeptide binding]; other site
1126011007613	active site
1126011007614	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1126011007615	nudix motif; other site
1126011007616	general stress protein 13; Validated; Region: PRK08059
1126011007617	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1126011007618	RNA binding site [nucleotide binding]; other site
1126011007619	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1126011007620	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1126011007621	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011007622	homodimer interface [polypeptide binding]; other site
1126011007623	catalytic residue [active]
1126011007624	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1126011007625	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011007626	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011007627	Walker A/P-loop; other site
1126011007628	ATP binding site [chemical binding]; other site
1126011007629	Q-loop/lid; other site
1126011007630	ABC transporter signature motif; other site
1126011007631	Walker B; other site
1126011007632	D-loop; other site
1126011007633	H-loop/switch region; other site
1126011007634	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011007635	active site
1126011007636	P-loop; other site
1126011007637	phosphorylation site [posttranslational modification]
1126011007638	aspartate kinase; Reviewed; Region: PRK09034
1126011007639	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
1126011007640	putative catalytic residues [active]
1126011007641	putative nucleotide binding site [chemical binding]; other site
1126011007642	putative aspartate binding site [chemical binding]; other site
1126011007643	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
1126011007644	allosteric regulatory residue; other site
1126011007645	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
1126011007646	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1126011007647	putative active site [active]
1126011007648	putative NTP binding site [chemical binding]; other site
1126011007649	putative nucleic acid binding site [nucleotide binding]; other site
1126011007650	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
1126011007651	active site
1126011007652	drug efflux system protein MdtG; Provisional; Region: PRK09874
1126011007653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011007654	putative substrate translocation pore; other site
1126011007655	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
1126011007656	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1126011007657	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
1126011007658	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12573
1126011007659	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08600
1126011007660	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07691
1126011007661	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1126011007662	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
1126011007663	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12600
1126011007664	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12585
1126011007665	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1126011007666	CoenzymeA binding site [chemical binding]; other site
1126011007667	subunit interaction site [polypeptide binding]; other site
1126011007668	PHB binding site; other site
1126011007669	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1963
1126011007670	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1126011007671	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1126011007672	Cl- selectivity filter; other site
1126011007673	Cl- binding residues [ion binding]; other site
1126011007674	pore gating glutamate residue; other site
1126011007675	dimer interface [polypeptide binding]; other site
1126011007676	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011007677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3878
1126011007678	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1126011007679	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011007680	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1126011007681	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011007682	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011007683	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1126011007684	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1126011007685	NAD(P) binding site [chemical binding]; other site
1126011007686	putative active site [active]
1126011007687	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4844
1126011007688	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4837
1126011007689	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011007690	Leucine-rich repeats; other site
1126011007691	Substrate binding site [chemical binding]; other site
1126011007692	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011007693	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011007694	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011007695	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007696	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007697	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007698	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007699	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011007700	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1126011007701	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1126011007702	tetramer interfaces [polypeptide binding]; other site
1126011007703	binuclear metal-binding site [ion binding]; other site
1126011007704	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1126011007705	Domain of unknown function DUF21; Region: DUF21; pfam01595
1126011007706	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1126011007707	Transporter associated domain; Region: CorC_HlyC; smart01091
1126011007708	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1126011007709	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011007710	Coenzyme A binding pocket [chemical binding]; other site
1126011007711	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
1126011007712	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007713	active site
1126011007714	motif I; other site
1126011007715	motif II; other site
1126011007716	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4470
1126011007718	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1126011007719	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1126011007720	active site
1126011007721	metal binding site [ion binding]; metal-binding site
1126011007722	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1126011007723	Predicted permeases [General function prediction only]; Region: COG0730
1126011007724	Predicted membrane protein [Function unknown]; Region: COG4272
1126011007725	Uncharacterized conserved protein [Function unknown]; Region: COG1801
1126011007726	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1126011007727	FeS assembly protein SufB; Region: sufB; TIGR01980
1126011007728	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1126011007729	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1126011007730	trimerization site [polypeptide binding]; other site
1126011007731	active site
1126011007732	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1126011007733	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1126011007734	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011007735	catalytic residue [active]
1126011007736	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1126011007737	FeS assembly protein SufD; Region: sufD; TIGR01981
1126011007738	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1126011007739	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1126011007740	Walker A/P-loop; other site
1126011007741	ATP binding site [chemical binding]; other site
1126011007742	Q-loop/lid; other site
1126011007743	ABC transporter signature motif; other site
1126011007744	Walker B; other site
1126011007745	D-loop; other site
1126011007746	H-loop/switch region; other site
1126011007747	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1126011007748	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1126011007749	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011007750	ABC-ATPase subunit interface; other site
1126011007751	putative PBP binding loops; other site
1126011007752	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1126011007753	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1126011007754	Walker A/P-loop; other site
1126011007755	ATP binding site [chemical binding]; other site
1126011007756	Q-loop/lid; other site
1126011007757	ABC transporter signature motif; other site
1126011007758	Walker B; other site
1126011007759	D-loop; other site
1126011007760	H-loop/switch region; other site
1126011007761	NIL domain; Region: NIL; pfam09383
1126011007762	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011007763	dimer interface [polypeptide binding]; other site
1126011007764	phosphorylation site [posttranslational modification]
1126011007765	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011007766	ATP binding site [chemical binding]; other site
1126011007767	Mg2+ binding site [ion binding]; other site
1126011007768	G-X-G motif; other site
1126011007769	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011007770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011007771	active site
1126011007772	phosphorylation site [posttranslational modification]
1126011007773	intermolecular recognition site; other site
1126011007774	dimerization interface [polypeptide binding]; other site
1126011007775	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011007776	DNA binding site [nucleotide binding]
1126011007777	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1126011007778	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1126011007779	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011007780	catalytic residues [active]
1126011007781	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1126011007782	lipoyl attachment site [posttranslational modification]; other site
1126011007783	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
1126011007784	ArsC family; Region: ArsC; pfam03960
1126011007785	putative ArsC-like catalytic residues; other site
1126011007786	putative TRX-like catalytic residues [active]
1126011007787	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1126011007788	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1126011007789	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1126011007790	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1126011007791	Walker A/P-loop; other site
1126011007792	ATP binding site [chemical binding]; other site
1126011007793	Q-loop/lid; other site
1126011007794	ABC transporter signature motif; other site
1126011007795	Walker B; other site
1126011007796	D-loop; other site
1126011007797	H-loop/switch region; other site
1126011007798	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1126011007799	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1126011007800	ABC-ATPase subunit  interface; other site
1126011007801	dimer interface [polypeptide binding]; other site
1126011007802	putative PBP binding regions; other site
1126011007803	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1126011007804	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1126011007805	intersubunit interface [polypeptide binding]; other site
1126011007806	Predicted esterase [General function prediction only]; Region: COG0627
1126011007807	S-formylglutathione hydrolase; Region: PLN02442
1126011007808	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1126011007809	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011007810	catalytic residue [active]
1126011007811	SdpI/YhfL protein family; Region: SdpI; pfam13630
1126011007812	CAT RNA binding domain; Region: CAT_RBD; smart01061
1126011007813	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1126011007814	PRD domain; Region: PRD; pfam00874
1126011007815	PRD domain; Region: PRD; pfam00874
1126011007816	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
1126011007817	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
1126011007818	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
1126011007819	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1126011007820	Predicted transcriptional regulator [Transcription]; Region: COG2378
1126011007821	HTH domain; Region: HTH_11; pfam08279
1126011007822	WYL domain; Region: WYL; pfam13280
1126011007823	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1126011007824	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1126011007825	putative active site [active]
1126011007826	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011007827	Leucine rich repeat; Region: LRR_8; pfam13855
1126011007828	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1126011007829	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
1126011007830	active site
1126011007831	catalytic site [active]
1126011007832	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
1126011007833	putative metal binding site [ion binding]; other site
1126011007834	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
1126011007835	putative metal binding site [ion binding]; other site
1126011007836	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011007837	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1126011007838	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1126011007839	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
1126011007840	active site
1126011007841	catalytic site [active]
1126011007842	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
1126011007843	putative metal binding site [ion binding]; other site
1126011007844	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011007845	non-specific DNA binding site [nucleotide binding]; other site
1126011007846	salt bridge; other site
1126011007847	sequence-specific DNA binding site [nucleotide binding]; other site
1126011007848	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
1126011007849	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1126011007850	SmpB-tmRNA interface; other site
1126011007851	ribonuclease R; Region: RNase_R; TIGR02063
1126011007852	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1126011007853	RNB domain; Region: RNB; pfam00773
1126011007854	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1126011007855	RNA binding site [nucleotide binding]; other site
1126011007856	Esterase/lipase [General function prediction only]; Region: COG1647
1126011007857	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011007858	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1126011007859	Preprotein translocase SecG subunit; Region: SecG; cl09123
1126011007860	Esterase/lipase [General function prediction only]; Region: COG1647
1126011007861	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1126011007862	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1126011007863	PGAP1-like protein; Region: PGAP1; pfam07819
1126011007864	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1126011007865	enolase; Provisional; Region: eno; PRK00077
1126011007866	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1126011007867	dimer interface [polypeptide binding]; other site
1126011007868	metal binding site [ion binding]; metal-binding site
1126011007869	substrate binding pocket [chemical binding]; other site
1126011007870	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1126011007871	phosphoglyceromutase; Provisional; Region: PRK05434
1126011007872	triosephosphate isomerase; Provisional; Region: PRK14567
1126011007873	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1126011007874	substrate binding site [chemical binding]; other site
1126011007875	dimer interface [polypeptide binding]; other site
1126011007876	catalytic triad [active]
1126011007877	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1126011007878	Phosphoglycerate kinase; Region: PGK; pfam00162
1126011007879	substrate binding site [chemical binding]; other site
1126011007880	hinge regions; other site
1126011007881	ADP binding site [chemical binding]; other site
1126011007882	catalytic site [active]
1126011007883	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1126011007884	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1126011007885	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1126011007886	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1126011007887	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1126011007888	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1126011007889	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1126011007890	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1126011007891	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011007892	DNA binding site [nucleotide binding]
1126011007893	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1126011007894	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1126011007895	active site
1126011007896	dimer interface [polypeptide binding]; other site
1126011007897	MMPL family; Region: MMPL; pfam03176
1126011007898	Sterol-sensing domain of SREBP cleavage-activation; Region: Sterol-sensing; pfam12349
1126011007899	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011007900	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011007901	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
1126011007902	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3397
1126011007903	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1126011007904	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1126011007905	Interdomain contacts; other site
1126011007906	Cytokine receptor motif; other site
1126011007907	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1126011007908	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1126011007909	Interdomain contacts; other site
1126011007910	Cytokine receptor motif; other site
1126011007911	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1126011007912	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1126011007913	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1126011007914	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1126011007915	Clp protease; Region: CLP_protease; pfam00574
1126011007916	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1126011007917	oligomer interface [polypeptide binding]; other site
1126011007918	active site residues [active]
1126011007919	amino acid transporter; Region: 2A0306; TIGR00909
1126011007920	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1126011007921	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
1126011007922	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011007923	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011007924	Substrate binding site [chemical binding]; other site
1126011007925	Leucine rich repeat; Region: LRR_8; pfam13855
1126011007926	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011007927	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1126011007928	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1126011007929	active site
1126011007930	FMN binding site [chemical binding]; other site
1126011007931	substrate binding site [chemical binding]; other site
1126011007932	homotetramer interface [polypeptide binding]; other site
1126011007933	catalytic residue [active]
1126011007934	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1126011007935	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1126011007936	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1126011007937	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1126011007938	phosphate binding site [ion binding]; other site
1126011007939	putative substrate binding pocket [chemical binding]; other site
1126011007940	dimer interface [polypeptide binding]; other site
1126011007941	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1126011007942	AAA domain; Region: AAA_18; pfam13238
1126011007943	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1126011007944	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1126011007945	active site
1126011007946	substrate binding site [chemical binding]; other site
1126011007947	metal binding site [ion binding]; metal-binding site
1126011007948	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1126011007949	active site
1126011007950	catalytic residues [active]
1126011007951	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1126011007952	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1126011007953	NAD binding site [chemical binding]; other site
1126011007954	homodimer interface [polypeptide binding]; other site
1126011007955	active site
1126011007956	substrate binding site [chemical binding]; other site
1126011007957	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1126011007958	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1126011007959	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011007960	TPR repeat; Region: TPR_11; pfam13414
1126011007961	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011007962	binding surface
1126011007963	TPR motif; other site
1126011007964	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1126011007965	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1126011007966	binding surface
1126011007967	TPR motif; other site
1126011007968	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1126011007969	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1126011007970	putative trimer interface [polypeptide binding]; other site
1126011007971	putative CoA binding site [chemical binding]; other site
1126011007972	pyrophosphatase PpaX; Provisional; Region: PRK13288
1126011007973	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011007974	motif II; other site
1126011007975	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1126011007976	HPr kinase/phosphorylase; Provisional; Region: PRK05428
1126011007977	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1126011007978	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1126011007979	Hpr binding site; other site
1126011007980	active site
1126011007981	homohexamer subunit interaction site [polypeptide binding]; other site
1126011007982	Predicted membrane protein [Function unknown]; Region: COG1950
1126011007983	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
1126011007984	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
1126011007985	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1126011007986	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1126011007987	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1126011007988	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1126011007989	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1126011007990	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1126011007991	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1126011007992	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1126011007993	excinuclease ABC subunit B; Provisional; Region: PRK05298
1126011007994	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011007995	ATP binding site [chemical binding]; other site
1126011007996	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011007997	nucleotide binding region [chemical binding]; other site
1126011007998	ATP-binding site [chemical binding]; other site
1126011007999	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1126011008000	UvrB/uvrC motif; Region: UVR; pfam02151
1126011008001	Uncharacterized protein conserved in bacteria (DUF2198); Region: DUF2198; cl11559
1126011008002	HD containing hydrolase-like enzyme; Region: HD_2; pfam12917
1126011008003	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1126011008004	dimerization interface [polypeptide binding]; other site
1126011008005	putative DNA binding site [nucleotide binding]; other site
1126011008006	putative Zn2+ binding site [ion binding]; other site
1126011008007	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1126011008008	PhoU domain; Region: PhoU; pfam01895
1126011008009	PhoU domain; Region: PhoU; pfam01895
1126011008010	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1126011008011	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1126011008012	Walker A/P-loop; other site
1126011008013	ATP binding site [chemical binding]; other site
1126011008014	Q-loop/lid; other site
1126011008015	ABC transporter signature motif; other site
1126011008016	Walker B; other site
1126011008017	D-loop; other site
1126011008018	H-loop/switch region; other site
1126011008019	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1126011008020	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1126011008021	Walker A/P-loop; other site
1126011008022	ATP binding site [chemical binding]; other site
1126011008023	Q-loop/lid; other site
1126011008024	ABC transporter signature motif; other site
1126011008025	Walker B; other site
1126011008026	D-loop; other site
1126011008027	H-loop/switch region; other site
1126011008028	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1126011008029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011008030	dimer interface [polypeptide binding]; other site
1126011008031	conserved gate region; other site
1126011008032	putative PBP binding loops; other site
1126011008033	ABC-ATPase subunit interface; other site
1126011008034	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1126011008035	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011008036	dimer interface [polypeptide binding]; other site
1126011008037	conserved gate region; other site
1126011008038	putative PBP binding loops; other site
1126011008039	ABC-ATPase subunit interface; other site
1126011008040	PBP superfamily domain; Region: PBP_like_2; cl17296
1126011008041	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1126011008042	HAMP domain; Region: HAMP; pfam00672
1126011008043	dimerization interface [polypeptide binding]; other site
1126011008044	PAS domain; Region: PAS; smart00091
1126011008045	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1126011008046	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011008047	dimer interface [polypeptide binding]; other site
1126011008048	phosphorylation site [posttranslational modification]
1126011008049	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011008050	ATP binding site [chemical binding]; other site
1126011008051	Mg2+ binding site [ion binding]; other site
1126011008052	G-X-G motif; other site
1126011008053	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011008054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011008055	active site
1126011008056	phosphorylation site [posttranslational modification]
1126011008057	intermolecular recognition site; other site
1126011008058	dimerization interface [polypeptide binding]; other site
1126011008059	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011008060	DNA binding site [nucleotide binding]
1126011008061	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1126011008062	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1126011008063	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1126011008064	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1126011008065	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1126011008066	putative active site [active]
1126011008067	catalytic site [active]
1126011008068	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1126011008069	putative active site [active]
1126011008070	catalytic site [active]
1126011008071	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1126011008072	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1126011008073	Peptidase family M23; Region: Peptidase_M23; pfam01551
1126011008074	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1126011008075	NlpC/P60 family; Region: NLPC_P60; pfam00877
1126011008076	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1126011008077	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1126011008078	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1126011008079	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008080	Walker A/P-loop; other site
1126011008081	ATP binding site [chemical binding]; other site
1126011008082	Q-loop/lid; other site
1126011008083	ABC transporter signature motif; other site
1126011008084	Walker B; other site
1126011008085	D-loop; other site
1126011008086	H-loop/switch region; other site
1126011008087	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1126011008088	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011008089	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1126011008090	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1126011008091	peptide chain release factor 2; Provisional; Region: PRK06746
1126011008092	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1126011008093	RF-1 domain; Region: RF-1; pfam00472
1126011008094	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1126011008095	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1126011008096	nucleotide binding region [chemical binding]; other site
1126011008097	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1126011008098	ATP-binding site [chemical binding]; other site
1126011008099	SEC-C motif; Region: SEC-C; pfam02810
1126011008100	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1126011008101	30S subunit binding site; other site
1126011008102	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1126011008103	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011008104	active site
1126011008105	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
1126011008106	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011008107	ATP binding site [chemical binding]; other site
1126011008108	putative Mg++ binding site [ion binding]; other site
1126011008109	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011008110	nucleotide binding region [chemical binding]; other site
1126011008111	ATP-binding site [chemical binding]; other site
1126011008112	EDD domain protein, DegV family; Region: DegV; TIGR00762
1126011008113	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1126011008114	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1126011008115	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011008116	active site
1126011008117	phosphorylation site [posttranslational modification]
1126011008118	intermolecular recognition site; other site
1126011008119	dimerization interface [polypeptide binding]; other site
1126011008120	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1126011008121	DNA binding residues [nucleotide binding]
1126011008122	dimerization interface [polypeptide binding]; other site
1126011008123	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1126011008124	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1126011008125	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1126011008126	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1126011008127	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1126011008128	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1126011008129	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1126011008130	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1126011008131	Mg++ binding site [ion binding]; other site
1126011008132	putative catalytic motif [active]
1126011008133	substrate binding site [chemical binding]; other site
1126011008134	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
1126011008135	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
1126011008136	active site
1126011008137	octamer interface [polypeptide binding]; other site
1126011008138	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1126011008139	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1126011008140	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008141	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008142	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1126011008143	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1126011008144	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1126011008145	dimer interface [polypeptide binding]; other site
1126011008146	ssDNA binding site [nucleotide binding]; other site
1126011008147	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1126011008148	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1126011008149	rod shape-determining protein Mbl; Provisional; Region: PRK13928
1126011008150	MreB and similar proteins; Region: MreB_like; cd10225
1126011008151	nucleotide binding site [chemical binding]; other site
1126011008152	Mg binding site [ion binding]; other site
1126011008153	putative protofilament interaction site [polypeptide binding]; other site
1126011008154	RodZ interaction site [polypeptide binding]; other site
1126011008155	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1126011008156	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1126011008157	hinge; other site
1126011008158	active site
1126011008159	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
1126011008160	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1126011008161	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1126011008162	gamma subunit interface [polypeptide binding]; other site
1126011008163	epsilon subunit interface [polypeptide binding]; other site
1126011008164	LBP interface [polypeptide binding]; other site
1126011008165	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1126011008166	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1126011008167	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1126011008168	alpha subunit interaction interface [polypeptide binding]; other site
1126011008169	Walker A motif; other site
1126011008170	ATP binding site [chemical binding]; other site
1126011008171	Walker B motif; other site
1126011008172	inhibitor binding site; inhibition site
1126011008173	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1126011008174	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1126011008175	core domain interface [polypeptide binding]; other site
1126011008176	delta subunit interface [polypeptide binding]; other site
1126011008177	epsilon subunit interface [polypeptide binding]; other site
1126011008178	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1126011008179	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1126011008180	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1126011008181	beta subunit interaction interface [polypeptide binding]; other site
1126011008182	Walker A motif; other site
1126011008183	ATP binding site [chemical binding]; other site
1126011008184	Walker B motif; other site
1126011008185	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1126011008186	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1126011008187	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1126011008188	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1126011008189	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1126011008190	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1126011008191	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1126011008192	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1126011008193	ATP synthase I chain; Region: ATP_synt_I; pfam03899
1126011008194	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1126011008195	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1126011008196	active site
1126011008197	homodimer interface [polypeptide binding]; other site
1126011008198	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1126011008199	active site
1126011008200	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1126011008201	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1126011008202	dimer interface [polypeptide binding]; other site
1126011008203	active site
1126011008204	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1126011008205	folate binding site [chemical binding]; other site
1126011008206	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1126011008207	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1126011008208	active site
1126011008209	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1126011008210	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1126011008211	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1126011008212	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011008213	S-adenosylmethionine binding site [chemical binding]; other site
1126011008214	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1126011008215	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1126011008216	RF-1 domain; Region: RF-1; pfam00472
1126011008217	thymidine kinase; Provisional; Region: PRK04296
1126011008218	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1126011008219	ATP binding site [chemical binding]; other site
1126011008220	Walker A motif; other site
1126011008221	Walker B motif; other site
1126011008222	homoserine kinase; Provisional; Region: PRK01212
1126011008223	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1126011008224	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1126011008225	threonine synthase; Reviewed; Region: PRK06721
1126011008226	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1126011008227	homodimer interface [polypeptide binding]; other site
1126011008228	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011008229	catalytic residue [active]
1126011008230	homoserine dehydrogenase; Provisional; Region: PRK06349
1126011008231	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1126011008232	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1126011008233	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1126011008234	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1126011008235	Predicted membrane protein [Function unknown]; Region: COG2246
1126011008236	GtrA-like protein; Region: GtrA; pfam04138
1126011008237	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1126011008238	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1126011008239	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1126011008240	RNA binding site [nucleotide binding]; other site
1126011008241	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1126011008242	multimer interface [polypeptide binding]; other site
1126011008243	Walker A motif; other site
1126011008244	ATP binding site [chemical binding]; other site
1126011008245	Walker B motif; other site
1126011008246	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1126011008247	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1126011008248	hinge; other site
1126011008249	active site
1126011008250	Predicted integral membrane protein [Function unknown]; Region: COG0392
1126011008251	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1126011008252	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1126011008253	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1126011008254	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1126011008255	putative ADP-binding pocket [chemical binding]; other site
1126011008256	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1126011008257	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1126011008258	intersubunit interface [polypeptide binding]; other site
1126011008259	active site
1126011008260	zinc binding site [ion binding]; other site
1126011008261	Na+ binding site [ion binding]; other site
1126011008262	putative lipid kinase; Reviewed; Region: PRK13055
1126011008263	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1126011008264	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: COG5632
1126011008265	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1126011008266	substrate binding site [chemical binding]; other site
1126011008267	SH3-like domain; Region: SH3_8; pfam13457
1126011008268	SH3-like domain; Region: SH3_8; pfam13457
1126011008269	SH3-like domain; Region: SH3_8; pfam13457
1126011008270	CTP synthetase; Validated; Region: pyrG; PRK05380
1126011008271	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1126011008272	Catalytic site [active]
1126011008273	active site
1126011008274	UTP binding site [chemical binding]; other site
1126011008275	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1126011008276	active site
1126011008277	putative oxyanion hole; other site
1126011008278	catalytic triad [active]
1126011008279	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
1126011008280	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1126011008281	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1126011008282	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1126011008283	active site
1126011008284	HIGH motif; other site
1126011008285	KMSK motif region; other site
1126011008286	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1126011008287	tRNA binding surface [nucleotide binding]; other site
1126011008288	anticodon binding site; other site
1126011008289	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4506
1126011008290	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1126011008291	Peptidase family M50; Region: Peptidase_M50; pfam02163
1126011008292	active site
1126011008293	putative substrate binding region [chemical binding]; other site
1126011008294	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1126011008295	active site 1 [active]
1126011008296	dimer interface [polypeptide binding]; other site
1126011008297	hexamer interface [polypeptide binding]; other site
1126011008298	active site 2 [active]
1126011008299	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1126011008300	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011008301	Zn2+ binding site [ion binding]; other site
1126011008302	Mg2+ binding site [ion binding]; other site
1126011008303	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1126011008304	conserved hypothetical protein TIGR01655; Region: yxeA_fam
1126011008305	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1126011008306	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1126011008307	peptide binding site [polypeptide binding]; other site
1126011008308	Predicted integral membrane protein [Function unknown]; Region: COG5658
1126011008309	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1126011008310	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1126011008311	catalytic triad [active]
1126011008312	metal binding site [ion binding]; metal-binding site
1126011008313	conserved cis-peptide bond; other site
1126011008314	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
1126011008315	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1126011008316	folate binding site [chemical binding]; other site
1126011008317	NADP+ binding site [chemical binding]; other site
1126011008318	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1126011008319	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1126011008320	putative NAD(P) binding site [chemical binding]; other site
1126011008321	dimer interface [polypeptide binding]; other site
1126011008322	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1126011008323	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1126011008324	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011008325	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011008326	active site
1126011008327	motif I; other site
1126011008328	motif II; other site
1126011008329	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1126011008330	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1126011008331	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1126011008332	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011008333	Walker A/P-loop; other site
1126011008334	ATP binding site [chemical binding]; other site
1126011008335	Q-loop/lid; other site
1126011008336	ABC transporter signature motif; other site
1126011008337	Walker B; other site
1126011008338	D-loop; other site
1126011008339	H-loop/switch region; other site
1126011008340	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1126011008341	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1126011008342	FtsX-like permease family; Region: FtsX; pfam02687
1126011008343	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1126011008344	dimerization interface [polypeptide binding]; other site
1126011008345	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011008346	dimer interface [polypeptide binding]; other site
1126011008347	phosphorylation site [posttranslational modification]
1126011008348	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011008349	ATP binding site [chemical binding]; other site
1126011008350	Mg2+ binding site [ion binding]; other site
1126011008351	G-X-G motif; other site
1126011008352	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011008353	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011008354	active site
1126011008355	phosphorylation site [posttranslational modification]
1126011008356	intermolecular recognition site; other site
1126011008357	dimerization interface [polypeptide binding]; other site
1126011008358	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011008359	DNA binding site [nucleotide binding]
1126011008360	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1126011008361	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1126011008362	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1126011008363	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1126011008364	catalytic loop [active]
1126011008365	iron binding site [ion binding]; other site
1126011008366	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1126011008367	4Fe-4S binding domain; Region: Fer4; pfam00037
1126011008368	4Fe-4S binding domain; Region: Fer4; pfam00037
1126011008369	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1126011008370	[4Fe-4S] binding site [ion binding]; other site
1126011008371	molybdopterin cofactor binding site; other site
1126011008372	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1126011008373	molybdopterin cofactor binding site; other site
1126011008374	Uncharacterized conserved protein [Function unknown]; Region: COG1912
1126011008375	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011008376	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011008377	putative substrate translocation pore; other site
1126011008378	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011008379	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011008380	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1126011008381	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1126011008382	Walker A motif; other site
1126011008383	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011008384	SH3-like domain; Region: SH3_8; pfam13457
1126011008385	SH3-like domain; Region: SH3_8; pfam13457
1126011008386	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011008387	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011008388	active site
1126011008389	catalytic tetrad [active]
1126011008390	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011008391	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011008392	DNA binding residues [nucleotide binding]
1126011008393	putative dimer interface [polypeptide binding]; other site
1126011008394	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1126011008395	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1126011008396	23S rRNA interface [nucleotide binding]; other site
1126011008397	L3 interface [polypeptide binding]; other site
1126011008398	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1126011008399	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1126011008400	dimerization interface 3.5A [polypeptide binding]; other site
1126011008401	active site
1126011008402	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1126011008403	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
1126011008404	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1126011008405	Walker A/P-loop; other site
1126011008406	ATP binding site [chemical binding]; other site
1126011008407	Q-loop/lid; other site
1126011008408	ABC transporter signature motif; other site
1126011008409	Walker B; other site
1126011008410	D-loop; other site
1126011008411	H-loop/switch region; other site
1126011008412	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
1126011008413	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1126011008414	Walker A/P-loop; other site
1126011008415	ATP binding site [chemical binding]; other site
1126011008416	Q-loop/lid; other site
1126011008417	ABC transporter signature motif; other site
1126011008418	Walker B; other site
1126011008419	D-loop; other site
1126011008420	H-loop/switch region; other site
1126011008421	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1126011008422	MgtC family; Region: MgtC; pfam02308
1126011008423	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
1126011008424	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1126011008425	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1126011008426	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1126011008427	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1126011008428	alphaNTD - beta interaction site [polypeptide binding]; other site
1126011008429	alphaNTD homodimer interface [polypeptide binding]; other site
1126011008430	alphaNTD - beta' interaction site [polypeptide binding]; other site
1126011008431	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1126011008432	30S ribosomal protein S11; Validated; Region: PRK05309
1126011008433	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1126011008434	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1126011008435	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1126011008436	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1126011008437	rRNA binding site [nucleotide binding]; other site
1126011008438	predicted 30S ribosome binding site; other site
1126011008439	adenylate kinase; Reviewed; Region: adk; PRK00279
1126011008440	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1126011008441	AMP-binding site [chemical binding]; other site
1126011008442	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1126011008443	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1126011008444	SecY translocase; Region: SecY; pfam00344
1126011008445	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1126011008446	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1126011008447	23S rRNA binding site [nucleotide binding]; other site
1126011008448	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1126011008449	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1126011008450	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1126011008451	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1126011008452	5S rRNA interface [nucleotide binding]; other site
1126011008453	L27 interface [polypeptide binding]; other site
1126011008454	23S rRNA interface [nucleotide binding]; other site
1126011008455	L5 interface [polypeptide binding]; other site
1126011008456	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1126011008457	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1126011008458	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1126011008459	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1126011008460	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1126011008461	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1126011008462	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1126011008463	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1126011008464	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1126011008465	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1126011008466	RNA binding site [nucleotide binding]; other site
1126011008467	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1126011008468	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1126011008469	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1126011008470	23S rRNA interface [nucleotide binding]; other site
1126011008471	putative translocon interaction site; other site
1126011008472	signal recognition particle (SRP54) interaction site; other site
1126011008473	L23 interface [polypeptide binding]; other site
1126011008474	trigger factor interaction site; other site
1126011008475	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1126011008476	23S rRNA interface [nucleotide binding]; other site
1126011008477	5S rRNA interface [nucleotide binding]; other site
1126011008478	putative antibiotic binding site [chemical binding]; other site
1126011008479	L25 interface [polypeptide binding]; other site
1126011008480	L27 interface [polypeptide binding]; other site
1126011008481	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1126011008482	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1126011008483	G-X-X-G motif; other site
1126011008484	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1126011008485	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1126011008486	putative translocon binding site; other site
1126011008487	protein-rRNA interface [nucleotide binding]; other site
1126011008488	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1126011008489	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1126011008490	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1126011008491	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1126011008492	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1126011008493	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1126011008494	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1126011008495	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1126011008496	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1126011008497	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional; Region: PRK13387
1126011008498	UbiA prenyltransferase family; Region: UbiA; pfam01040
1126011008499	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1126011008500	ApbE family; Region: ApbE; pfam02424
1126011008501	Major membrane immunogen, membrane-anchored lipoprotein [Function unknown]; Region: COG4939
1126011008502	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
1126011008503	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
1126011008504	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1126011008505	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1126011008506	Predicted membrane protein [Function unknown]; Region: COG2259
1126011008507	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
1126011008508	trimer interface [polypeptide binding]; other site
1126011008509	Predicted membrane protein [Function unknown]; Region: COG4769
1126011008510	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1126011008511	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1126011008512	substrate binding pocket [chemical binding]; other site
1126011008513	chain length determination region; other site
1126011008514	substrate-Mg2+ binding site; other site
1126011008515	catalytic residues [active]
1126011008516	aspartate-rich region 1; other site
1126011008517	active site lid residues [active]
1126011008518	aspartate-rich region 2; other site
1126011008519	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1126011008520	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
1126011008521	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1126011008522	active site
1126011008523	metal binding site [ion binding]; metal-binding site
1126011008524	Protein of unknown function (DUF4003); Region: DUF4003; pfam13170
1126011008525	hypothetical protein; Provisional; Region: PRK02947
1126011008526	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011008527	putative active site [active]
1126011008528	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
1126011008529	Uncharacterized protein, putative amidase [General function prediction only]; Region: COG1402
1126011008530	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1126011008531	active site
1126011008532	substrate binding pocket [chemical binding]; other site
1126011008533	homodimer interaction site [polypeptide binding]; other site
1126011008534	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1126011008535	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1126011008536	active site
1126011008537	P-loop; other site
1126011008538	phosphorylation site [posttranslational modification]
1126011008539	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011008540	active site
1126011008541	phosphorylation site [posttranslational modification]
1126011008542	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011008543	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011008544	PRD domain; Region: PRD; pfam00874
1126011008545	PRD domain; Region: PRD; pfam00874
1126011008546	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011008547	active site
1126011008548	P-loop; other site
1126011008549	phosphorylation site [posttranslational modification]
1126011008550	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011008551	active site
1126011008552	phosphorylation site [posttranslational modification]
1126011008553	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1126011008554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008555	Walker A/P-loop; other site
1126011008556	ATP binding site [chemical binding]; other site
1126011008557	Q-loop/lid; other site
1126011008558	ABC transporter signature motif; other site
1126011008559	Walker B; other site
1126011008560	D-loop; other site
1126011008561	H-loop/switch region; other site
1126011008562	elongation factor Tu; Reviewed; Region: PRK00049
1126011008563	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1126011008564	G1 box; other site
1126011008565	GEF interaction site [polypeptide binding]; other site
1126011008566	GTP/Mg2+ binding site [chemical binding]; other site
1126011008567	Switch I region; other site
1126011008568	G2 box; other site
1126011008569	G3 box; other site
1126011008570	Switch II region; other site
1126011008571	G4 box; other site
1126011008572	G5 box; other site
1126011008573	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1126011008574	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1126011008575	Antibiotic Binding Site [chemical binding]; other site
1126011008576	elongation factor G; Reviewed; Region: PRK00007
1126011008577	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1126011008578	G1 box; other site
1126011008579	putative GEF interaction site [polypeptide binding]; other site
1126011008580	GTP/Mg2+ binding site [chemical binding]; other site
1126011008581	Switch I region; other site
1126011008582	G2 box; other site
1126011008583	G3 box; other site
1126011008584	Switch II region; other site
1126011008585	G4 box; other site
1126011008586	G5 box; other site
1126011008587	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1126011008588	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1126011008589	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1126011008590	30S ribosomal protein S7; Validated; Region: PRK05302
1126011008591	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1126011008592	S17 interaction site [polypeptide binding]; other site
1126011008593	S8 interaction site; other site
1126011008594	16S rRNA interaction site [nucleotide binding]; other site
1126011008595	streptomycin interaction site [chemical binding]; other site
1126011008596	23S rRNA interaction site [nucleotide binding]; other site
1126011008597	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1126011008598	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
1126011008599	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1126011008600	Zn2+ binding site [ion binding]; other site
1126011008601	Mg2+ binding site [ion binding]; other site
1126011008602	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1126011008603	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011008604	Coenzyme A binding pocket [chemical binding]; other site
1126011008605	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1126011008606	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011008607	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011008608	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1126011008609	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1126011008610	substrate binding site [chemical binding]; other site
1126011008611	hexamer interface [polypeptide binding]; other site
1126011008612	metal binding site [ion binding]; metal-binding site
1126011008613	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1126011008614	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1126011008615	TPP-binding site [chemical binding]; other site
1126011008616	dimer interface [polypeptide binding]; other site
1126011008617	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1126011008618	PYR/PP interface [polypeptide binding]; other site
1126011008619	dimer interface [polypeptide binding]; other site
1126011008620	TPP binding site [chemical binding]; other site
1126011008621	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1126011008622	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1126011008623	substrate binding site [chemical binding]; other site
1126011008624	hexamer interface [polypeptide binding]; other site
1126011008625	metal binding site [ion binding]; metal-binding site
1126011008626	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1126011008627	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1126011008628	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1126011008629	putative NAD(P) binding site [chemical binding]; other site
1126011008630	catalytic Zn binding site [ion binding]; other site
1126011008631	structural Zn binding site [ion binding]; other site
1126011008632	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1126011008633	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1126011008634	putative NAD(P) binding site [chemical binding]; other site
1126011008635	catalytic Zn binding site [ion binding]; other site
1126011008636	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1126011008637	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1126011008638	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1126011008639	active site
1126011008640	P-loop; other site
1126011008641	phosphorylation site [posttranslational modification]
1126011008642	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011008643	active site
1126011008644	phosphorylation site [posttranslational modification]
1126011008645	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011008646	PRD domain; Region: PRD; pfam00874
1126011008647	PRD domain; Region: PRD; pfam00874
1126011008648	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011008649	active site
1126011008650	P-loop; other site
1126011008651	phosphorylation site [posttranslational modification]
1126011008652	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: PtsN; COG1762
1126011008653	active site
1126011008654	phosphorylation site [posttranslational modification]
1126011008655	Predicted membrane protein [Function unknown]; Region: COG4905
1126011008656	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
1126011008657	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1126011008658	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1126011008659	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1126011008660	active site
1126011008661	Helix-turn-helix domain; Region: HTH_18; pfam12833
1126011008662	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1126011008663	Ligand Binding Site [chemical binding]; other site
1126011008664	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1126011008665	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
1126011008666	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1126011008667	active site
1126011008668	DNA binding site [nucleotide binding]
1126011008669	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1126011008670	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1126011008671	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1126011008672	active site
1126011008673	phosphorylation site [posttranslational modification]
1126011008674	intermolecular recognition site; other site
1126011008675	dimerization interface [polypeptide binding]; other site
1126011008676	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1126011008677	DNA binding site [nucleotide binding]
1126011008678	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
1126011008679	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1126011008680	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1126011008681	Ligand Binding Site [chemical binding]; other site
1126011008682	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1126011008683	GAF domain; Region: GAF_3; pfam13492
1126011008684	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1126011008685	dimer interface [polypeptide binding]; other site
1126011008686	phosphorylation site [posttranslational modification]
1126011008687	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1126011008688	ATP binding site [chemical binding]; other site
1126011008689	Mg2+ binding site [ion binding]; other site
1126011008690	G-X-G motif; other site
1126011008691	K+-transporting ATPase, c chain [Inorganic ion transport and metabolism]; Region: KdpC; COG2156
1126011008692	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1126011008693	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011008694	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1126011008695	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011008696	active site
1126011008697	P-loop; other site
1126011008698	phosphorylation site [posttranslational modification]
1126011008699	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011008700	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011008701	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011008702	methionine cluster; other site
1126011008703	active site
1126011008704	phosphorylation site [posttranslational modification]
1126011008705	metal binding site [ion binding]; metal-binding site
1126011008706	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1126011008707	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1126011008708	magnesium-translocating P-type ATPase; Region: ATPase-IIIB_Mg; TIGR01524
1126011008709	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1126011008710	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1126011008711	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1126011008712	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1126011008713	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1126011008714	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011008715	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011008716	autolysin; Reviewed; Region: PRK06347
1126011008717	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1126011008718	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008719	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008720	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008721	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1126011008722	Protein of unknown function (DUF970); Region: DUF970; pfam06153
1126011008723	thymidylate kinase; Validated; Region: tmk; PRK00698
1126011008724	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1126011008725	TMP-binding site; other site
1126011008726	ATP-binding site [chemical binding]; other site
1126011008727	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1126011008728	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1126011008729	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011008730	catalytic residue [active]
1126011008731	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1126011008732	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
1126011008733	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1126011008734	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1126011008735	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
1126011008736	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
1126011008737	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011008738	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011008739	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011008740	putative active site [active]
1126011008741	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1126011008742	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011008743	active site
1126011008744	motif I; other site
1126011008745	motif II; other site
1126011008746	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1126011008747	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1126011008748	nudix motif; other site
1126011008749	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1126011008750	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1126011008751	active site
1126011008752	catalytic tetrad [active]
1126011008753	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
1126011008754	recombination protein RecR; Reviewed; Region: recR; PRK00076
1126011008755	RecR protein; Region: RecR; pfam02132
1126011008756	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1126011008757	putative active site [active]
1126011008758	putative metal-binding site [ion binding]; other site
1126011008759	tetramer interface [polypeptide binding]; other site
1126011008760	hypothetical protein; Validated; Region: PRK00153
1126011008761	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
1126011008762	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1126011008763	Walker A motif; other site
1126011008764	ATP binding site [chemical binding]; other site
1126011008765	Walker B motif; other site
1126011008766	arginine finger; other site
1126011008767	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1126011008768	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
1126011008769	Protein of unknown function (DUF3188); Region: DUF3188; pfam11384
1126011008770	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011008771	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011008772	Domain of unknown function (DUF4307); Region: DUF4307; pfam14155
1126011008773	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1126011008774	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1126011008775	N- and C-terminal domain interface [polypeptide binding]; other site
1126011008776	active site
1126011008777	catalytic site [active]
1126011008778	metal binding site [ion binding]; metal-binding site
1126011008779	carbohydrate binding site [chemical binding]; other site
1126011008780	ATP binding site [chemical binding]; other site
1126011008781	SH3-like domain; Region: SH3_8; pfam13457
1126011008782	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
1126011008783	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1126011008784	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011008785	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1126011008786	Walker A/P-loop; other site
1126011008787	ATP binding site [chemical binding]; other site
1126011008788	Q-loop/lid; other site
1126011008789	ABC transporter signature motif; other site
1126011008790	Walker B; other site
1126011008791	D-loop; other site
1126011008792	H-loop/switch region; other site
1126011008793	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1126011008794	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011008795	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008796	Walker A/P-loop; other site
1126011008797	ATP binding site [chemical binding]; other site
1126011008798	Q-loop/lid; other site
1126011008799	ABC transporter signature motif; other site
1126011008800	Walker B; other site
1126011008801	D-loop; other site
1126011008802	H-loop/switch region; other site
1126011008803	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1126011008804	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1126011008805	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1126011008806	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1126011008807	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1126011008808	nucleoside/Zn binding site; other site
1126011008809	dimer interface [polypeptide binding]; other site
1126011008810	catalytic motif [active]
1126011008811	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1126011008812	Medium-chain acyl-CoA synthetase (MACS or ACSM); Region: MACS_like; cd05972
1126011008813	active site
1126011008814	acyl-activating enzyme (AAE) consensus motif; other site
1126011008815	putative CoA binding site [chemical binding]; other site
1126011008816	AMP binding site [chemical binding]; other site
1126011008817	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1126011008818	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1126011008819	active site
1126011008820	trimer interface [polypeptide binding]; other site
1126011008821	allosteric site; other site
1126011008822	active site lid [active]
1126011008823	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1126011008824	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1126011008825	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1126011008826	DNA binding residues [nucleotide binding]
1126011008827	drug binding residues [chemical binding]; other site
1126011008828	dimer interface [polypeptide binding]; other site
1126011008829	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1126011008830	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1126011008831	Coenzyme A binding pocket [chemical binding]; other site
1126011008832	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1126011008833	dimer interface [polypeptide binding]; other site
1126011008834	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1126011008835	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1126011008836	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1126011008837	MarR family; Region: MarR; pfam01047
1126011008838	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1126011008839	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1126011008840	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1126011008841	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1126011008842	DNA binding residues [nucleotide binding]
1126011008843	putative dimer interface [polypeptide binding]; other site
1126011008844	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1126011008845	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1126011008846	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011008847	active site
1126011008848	motif I; other site
1126011008849	motif II; other site
1126011008850	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011008851	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011008852	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011008853	putative active site [active]
1126011008854	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1126011008855	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011008856	active site
1126011008857	phosphorylation site [posttranslational modification]
1126011008858	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1126011008859	active site
1126011008860	P-loop; other site
1126011008861	phosphorylation site [posttranslational modification]
1126011008862	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1126011008863	alpha-mannosidase; Provisional; Region: PRK09819
1126011008864	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1126011008865	active site
1126011008866	metal binding site [ion binding]; metal-binding site
1126011008867	catalytic site [active]
1126011008868	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
1126011008869	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1126011008870	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1126011008871	active site
1126011008872	homodimer interface [polypeptide binding]; other site
1126011008873	catalytic site [active]
1126011008874	glycerate kinase; Region: TIGR00045
1126011008875	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011008876	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011008877	DNA binding site [nucleotide binding]
1126011008878	domain linker motif; other site
1126011008879	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1126011008880	putative dimerization interface [polypeptide binding]; other site
1126011008881	putative ligand binding site [chemical binding]; other site
1126011008882	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1126011008883	Domain of unknown function DUF21; Region: DUF21; pfam01595
1126011008884	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1126011008885	Transporter associated domain; Region: CorC_HlyC; pfam03471
1126011008886	NAD-dependent deacetylase; Provisional; Region: PRK00481
1126011008887	SIR2H: Uncharacterized prokaryotic Sir2 homologs from several gram positive bacterial species and Fusobacteria; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone...; Region: SIR2H; cd01411
1126011008888	NAD+ binding site [chemical binding]; other site
1126011008889	substrate binding site [chemical binding]; other site
1126011008890	putative Zn binding site [ion binding]; other site
1126011008891	Pathogenicity locus; Region: Cdd1; pfam11731
1126011008892	drug efflux system protein MdtG; Provisional; Region: PRK09874
1126011008893	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011008894	putative substrate translocation pore; other site
1126011008895	Src Homology 3 domain superfamily; Region: SH3; cl17036
1126011008896	Variant SH3 domain; Region: SH3_2; pfam07653
1126011008897	peptide ligand binding site [polypeptide binding]; other site
1126011008898	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1126011008899	active site
1126011008900	intersubunit interactions; other site
1126011008901	catalytic residue [active]
1126011008902	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1126011008903	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1126011008904	ligand binding site [chemical binding]; other site
1126011008905	flexible hinge region; other site
1126011008906	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1126011008907	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011008908	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011008909	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008910	Walker A/P-loop; other site
1126011008911	ATP binding site [chemical binding]; other site
1126011008912	Q-loop/lid; other site
1126011008913	ABC transporter signature motif; other site
1126011008914	Walker B; other site
1126011008915	D-loop; other site
1126011008916	H-loop/switch region; other site
1126011008917	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1126011008918	seryl-tRNA synthetase; Provisional; Region: PRK05431
1126011008919	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1126011008920	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1126011008921	dimer interface [polypeptide binding]; other site
1126011008922	active site
1126011008923	motif 1; other site
1126011008924	motif 2; other site
1126011008925	motif 3; other site
1126011008926	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
1126011008927	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1126011008928	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1126011008929	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1126011008930	glutamine binding [chemical binding]; other site
1126011008931	catalytic triad [active]
1126011008932	aminodeoxychorismate synthase; Provisional; Region: PRK07508
1126011008933	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1126011008934	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1126011008935	substrate-cofactor binding pocket; other site
1126011008936	homodimer interface [polypeptide binding]; other site
1126011008937	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1126011008938	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1126011008939	catalytic residue [active]
1126011008940	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011008941	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011008942	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008943	Walker A/P-loop; other site
1126011008944	ATP binding site [chemical binding]; other site
1126011008945	Q-loop/lid; other site
1126011008946	ABC transporter signature motif; other site
1126011008947	Walker B; other site
1126011008948	D-loop; other site
1126011008949	H-loop/switch region; other site
1126011008950	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1126011008951	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1126011008952	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1126011008953	Walker A/P-loop; other site
1126011008954	ATP binding site [chemical binding]; other site
1126011008955	Q-loop/lid; other site
1126011008956	ABC transporter signature motif; other site
1126011008957	Walker B; other site
1126011008958	D-loop; other site
1126011008959	H-loop/switch region; other site
1126011008960	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
1126011008961	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1126011008962	Ligand binding site; other site
1126011008963	Putative Catalytic site; other site
1126011008964	DXD motif; other site
1126011008965	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1126011008966	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1126011008967	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1126011008968	Predicted acyl esterases [General function prediction only]; Region: COG2936
1126011008969	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1126011008970	DNA topoisomerase III; Provisional; Region: PRK07726
1126011008971	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1126011008972	active site
1126011008973	putative interdomain interaction site [polypeptide binding]; other site
1126011008974	putative metal-binding site [ion binding]; other site
1126011008975	putative nucleotide binding site [chemical binding]; other site
1126011008976	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1126011008977	domain I; other site
1126011008978	DNA binding groove [nucleotide binding]
1126011008979	phosphate binding site [ion binding]; other site
1126011008980	domain II; other site
1126011008981	domain III; other site
1126011008982	nucleotide binding site [chemical binding]; other site
1126011008983	catalytic site [active]
1126011008984	domain IV; other site
1126011008985	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1126011008986	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1126011008987	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1126011008988	ATP binding site [chemical binding]; other site
1126011008989	putative Mg++ binding site [ion binding]; other site
1126011008990	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1126011008991	nucleotide binding region [chemical binding]; other site
1126011008992	ATP-binding site [chemical binding]; other site
1126011008993	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1126011008994	HRDC domain; Region: HRDC; pfam00570
1126011008995	IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]; Region: GuaB; COG0516
1126011008996	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1126011008997	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1126011008998	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1126011008999	active site
1126011009000	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1126011009001	putative ADP-ribose binding site [chemical binding]; other site
1126011009002	putative active site [active]
1126011009003	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1126011009004	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011009005	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011009006	ABC transporter; Region: ABC_tran_2; pfam12848
1126011009007	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1126011009008	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1126011009009	beta-galactosidase; Region: BGL; TIGR03356
1126011009010	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011009011	active site
1126011009012	P-loop; other site
1126011009013	phosphorylation site [posttranslational modification]
1126011009014	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1126011009015	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011009016	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011009017	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011009018	nucleotide binding site [chemical binding]; other site
1126011009019	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011009020	methionine cluster; other site
1126011009021	active site
1126011009022	phosphorylation site [posttranslational modification]
1126011009023	metal binding site [ion binding]; metal-binding site
1126011009024	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011009025	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011009026	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011009027	putative active site [active]
1126011009028	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
1126011009029	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1126011009030	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1126011009031	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1126011009032	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1126011009033	Walker A/P-loop; other site
1126011009034	ATP binding site [chemical binding]; other site
1126011009035	Q-loop/lid; other site
1126011009036	ABC transporter signature motif; other site
1126011009037	Walker B; other site
1126011009038	D-loop; other site
1126011009039	H-loop/switch region; other site
1126011009040	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
1126011009041	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
1126011009042	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1126011009043	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1126011009044	beta-galactosidase; Region: BGL; TIGR03356
1126011009045	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1126011009046	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1126011009047	active site turn [active]
1126011009048	phosphorylation site [posttranslational modification]
1126011009049	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1126011009050	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1126011009051	HPr interaction site; other site
1126011009052	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1126011009053	active site
1126011009054	phosphorylation site [posttranslational modification]
1126011009055	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1126011009056	CAT RNA binding domain; Region: CAT_RBD; smart01061
1126011009057	PRD domain; Region: PRD; pfam00874
1126011009058	PRD domain; Region: PRD; pfam00874
1126011009059	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1126011009060	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1126011009061	Walker A/P-loop; other site
1126011009062	ATP binding site [chemical binding]; other site
1126011009063	Q-loop/lid; other site
1126011009064	ABC transporter signature motif; other site
1126011009065	Walker B; other site
1126011009066	D-loop; other site
1126011009067	H-loop/switch region; other site
1126011009068	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
1126011009069	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
1126011009070	bacteriocin, lactococcin 972 family; Region: lactococcin_972; TIGR01653
1126011009071	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1126011009072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009073	putative substrate translocation pore; other site
1126011009074	GTP-binding protein YchF; Reviewed; Region: PRK09601
1126011009075	YchF GTPase; Region: YchF; cd01900
1126011009076	G1 box; other site
1126011009077	GTP/Mg2+ binding site [chemical binding]; other site
1126011009078	Switch I region; other site
1126011009079	G2 box; other site
1126011009080	Switch II region; other site
1126011009081	G3 box; other site
1126011009082	G4 box; other site
1126011009083	G5 box; other site
1126011009084	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1126011009085	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1126011009086	methionine cluster; other site
1126011009087	active site
1126011009088	phosphorylation site [posttranslational modification]
1126011009089	metal binding site [ion binding]; metal-binding site
1126011009090	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1126011009091	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1126011009092	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1126011009093	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1126011009094	active site
1126011009095	P-loop; other site
1126011009096	phosphorylation site [posttranslational modification]
1126011009097	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1126011009098	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1126011009099	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1126011009100	HTH domain; Region: HTH_11; pfam08279
1126011009101	Mga helix-turn-helix domain; Region: Mga; pfam05043
1126011009102	PRD domain; Region: PRD; pfam00874
1126011009103	PRD domain; Region: PRD; pfam00874
1126011009104	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1126011009105	active site
1126011009106	P-loop; other site
1126011009107	phosphorylation site [posttranslational modification]
1126011009108	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011009109	active site
1126011009110	phosphorylation site [posttranslational modification]
1126011009111	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1126011009112	Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154
1126011009113	tetramer interface [polypeptide binding]; other site
1126011009114	heme binding pocket [chemical binding]; other site
1126011009115	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4481
1126011009116	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1126011009117	ParB-like nuclease domain; Region: ParB; smart00470
1126011009118	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1126011009119	salt bridge; other site
1126011009120	non-specific DNA binding site [nucleotide binding]; other site
1126011009121	sequence-specific DNA binding site [nucleotide binding]; other site
1126011009122	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1126011009123	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1126011009124	P-loop; other site
1126011009125	Magnesium ion binding site [ion binding]; other site
1126011009126	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1126011009127	Magnesium ion binding site [ion binding]; other site
1126011009128	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1126011009129	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1126011009130	non-specific DNA binding site [nucleotide binding]; other site
1126011009131	salt bridge; other site
1126011009132	sequence-specific DNA binding site [nucleotide binding]; other site
1126011009133	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1126011009134	ParB-like nuclease domain; Region: ParBc; pfam02195
1126011009135	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1126011009136	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1126011009137	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1126011009138	putative active site [active]
1126011009139	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1126011009140	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1126011009141	nucleotide binding site [chemical binding]; other site
1126011009142	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1126011009143	active site
1126011009144	phosphorylation site [posttranslational modification]
1126011009145	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1126011009146	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011009147	motif II; other site
1126011009148	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1126011009149	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1126011009150	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1126011009151	active site
1126011009152	P-loop; other site
1126011009153	phosphorylation site [posttranslational modification]
1126011009154	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011009155	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011009156	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1126011009157	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1126011009158	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1126011009159	putative active site cavity [active]
1126011009160	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1126011009161	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1126011009162	S-adenosylmethionine binding site [chemical binding]; other site
1126011009163	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
1126011009164	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
1126011009165	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
1126011009166	Abi-like protein; Region: Abi_2; pfam07751
1126011009167	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1126011009168	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1126011009169	DNA binding site [nucleotide binding]
1126011009170	active site
1126011009171	Int/Topo IB signature motif; other site
1126011009172	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1126011009173	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1126011009174	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1126011009175	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1126011009176	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1126011009177	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1126011009178	G1 box; other site
1126011009179	GTP/Mg2+ binding site [chemical binding]; other site
1126011009180	Switch I region; other site
1126011009181	G2 box; other site
1126011009182	Switch II region; other site
1126011009183	G3 box; other site
1126011009184	G4 box; other site
1126011009185	G5 box; other site
1126011009186	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1126011009187	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1126011009188	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1126011009189	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1126011009190	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1126011009191	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1126011009192	tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362
1126011009193	NADP binding site [chemical binding]; other site
1126011009194	homodimer interface [polypeptide binding]; other site
1126011009195	active site
1126011009196	substrate binding site [chemical binding]; other site
1126011009197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009198	D-galactonate transporter; Region: 2A0114; TIGR00893
1126011009199	putative substrate translocation pore; other site
1126011009200	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1126011009201	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1126011009202	metal binding site [ion binding]; metal-binding site
1126011009203	dimer interface [polypeptide binding]; other site
1126011009204	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1126011009205	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1126011009206	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1126011009207	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1126011009208	metal binding site [ion binding]; metal-binding site
1126011009209	dimer interface [polypeptide binding]; other site
1126011009210	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011009211	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1126011009212	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664
1126011009213	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1126011009214	Leucine-rich repeats; other site
1126011009215	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011009216	Substrate binding site [chemical binding]; other site
1126011009217	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1126011009218	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011009219	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011009220	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011009221	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011009222	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
1126011009223	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
1126011009224	Uncharacterized conserved protein [Function unknown]; Region: COG4198
1126011009225	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
1126011009226	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
1126011009227	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1126011009228	putative ligand binding site [chemical binding]; other site
1126011009229	putative NAD binding site [chemical binding]; other site
1126011009230	putative catalytic site [active]
1126011009231	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1126011009232	L-serine binding site [chemical binding]; other site
1126011009233	ACT domain interface; other site
1126011009234	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
1126011009235	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1126011009236	catalytic residue [active]
1126011009237	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009238	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011009239	putative substrate translocation pore; other site
1126011009240	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1126011009241	MarR family; Region: MarR_2; pfam12802
1126011009242	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1126011009243	dimer interface [polypeptide binding]; other site
1126011009244	FMN binding site [chemical binding]; other site
1126011009245	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1126011009246	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1126011009247	catalytic residues [active]
1126011009248	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1126011009249	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1126011009250	motif II; other site
1126011009251	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1126011009252	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1126011009253	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1126011009254	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1126011009255	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1126011009256	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1126011009257	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1126011009258	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1126011009259	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1126011009260	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1126011009261	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1126011009262	putative NAD(P) binding site [chemical binding]; other site
1126011009263	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1126011009264	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011009265	dimer interface [polypeptide binding]; other site
1126011009266	conserved gate region; other site
1126011009267	putative PBP binding loops; other site
1126011009268	ABC-ATPase subunit interface; other site
1126011009269	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1126011009270	dimer interface [polypeptide binding]; other site
1126011009271	conserved gate region; other site
1126011009272	putative PBP binding loops; other site
1126011009273	ABC-ATPase subunit interface; other site
1126011009274	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1126011009275	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1126011009276	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1126011009277	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1126011009278	active site
1126011009279	homodimer interface [polypeptide binding]; other site
1126011009280	catalytic site [active]
1126011009281	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1126011009282	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1126011009283	DNA binding site [nucleotide binding]
1126011009284	domain linker motif; other site
1126011009285	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1126011009286	putative dimerization interface [polypeptide binding]; other site
1126011009287	putative ligand binding site [chemical binding]; other site
1126011009288	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1126011009289	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1126011009290	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1126011009291	Coenzyme A binding pocket [chemical binding]; other site
1126011009292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009293	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011009294	putative substrate translocation pore; other site
1126011009295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009296	Domain of unknown function (DUF718); Region: DUF718; cl01281
1126011009297	rhamnulose-1-phosphate aldolase; Region: rhamnu_1P_ald; TIGR02624
1126011009298	intersubunit interface [polypeptide binding]; other site
1126011009299	active site
1126011009300	Zn2+ binding site [ion binding]; other site
1126011009301	L-rhamnose isomerase; Provisional; Region: PRK01076
1126011009302	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1126011009303	N- and C-terminal domain interface [polypeptide binding]; other site
1126011009304	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1126011009305	active site
1126011009306	putative catalytic site [active]
1126011009307	metal binding site [ion binding]; metal-binding site
1126011009308	ATP binding site [chemical binding]; other site
1126011009309	carbohydrate binding site [chemical binding]; other site
1126011009310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1126011009311	putative substrate translocation pore; other site
1126011009312	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1126011009313	Cupin domain; Region: Cupin_2; pfam07883
1126011009314	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1126011009315	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1126011009316	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1126011009317	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1126011009318	G-X-X-G motif; other site
1126011009319	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1126011009320	RxxxH motif; other site
1126011009321	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1126011009322	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1126011009323	ribonuclease P; Reviewed; Region: rnpA; PRK00499
1126011009324	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399