-- dump date   	20140619_132421
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_463534.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
NP_463535.1	binds the polymerase to DNA and acts as a sliding clamp
NP_463538.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
NP_463550.1	CapA protein (polyglutamate capsule biosynthesis)
NP_463552.1	lmo0019
NP_463562.1	lmo0029
NP_463569.1	catalyzes the formation of putrescine from carbamoyl-putrescine during agmatine degradation
NP_463571.1	agmatine deiminase 1; catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis
NP_463572.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_463573.1	catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis
NP_463576.1	catalyzes the degradation of arginine to citruline and ammonia
NP_463577.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_463579.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
NP_463580.1	lmo0047
NP_463581.1	essential for production of a quorum sensing autoinducing peptide
NP_463582.1	lmo0049
NP_463586.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
NP_463587.1	unwinds double stranded DNA
NP_463588.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
NP_463591.1	lmo0058
NP_463595.1	lmo0062
NP_463596.1	lmo0063
NP_463597.1	lmo0064
NP_463598.1	lmo0065
NP_463601.1	lmo0068
NP_463602.1	lmo0069
NP_463603.1	lmo0070
NP_463604.1	lmo0071
NP_463606.1	lmo0073
NP_463607.1	lmo0074
NP_463612.1	lmo0079
NP_463613.1	lmo0080
NP_463614.1	lmo0081
NP_463615.1	lmo0082
NP_463618.1	lmo0085
NP_463619.1	lmo0086
NP_463620.1	lmo0087
NP_463623.1	produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit
NP_463625.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit
NP_463627.1	lmo0094
NP_463628.1	lmo0095
NP_463632.1	lmo0099
NP_463633.1	lmo0100
NP_463635.1	lmo0102
NP_463637.1	lmo0104
NP_463644.1	lmo0111
NP_463652.1	lmo0119
NP_463653.1	lmo0120
NP_463657.1	lmo0124
NP_463658.1	lmo0125
NP_463659.1	lmo0126
NP_463665.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
NP_463671.1	lmo0138
NP_463672.1	lmo0139
NP_463673.1	lmo0140
NP_463674.1	lmo0141
NP_463675.1	lmo0142
NP_463676.1	lmo0143
NP_463677.1	lmo0144
NP_463680.1	lmo0147
NP_463681.1	lmo0148
NP_463682.1	lmo0149
NP_463683.1	lmo0150
NP_463684.1	lmo0151
NP_463689.1	lmo0156
NP_463694.1	lmo0161
NP_463695.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
NP_463696.1	lmo0163
NP_463703.1	lmo0170
NP_463719.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
NP_463721.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
NP_463724.1	lmo0193
NP_463727.1	stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
NP_463728.1	stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
NP_463729.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
NP_463730.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
NP_463737.1	lmo0206
NP_463738.1	Uncharacterized lipoprotein Lmo0207 precursor.
NP_463740.1	lmo0209
NP_463741.1	Converts (S)-lactate and NAD(+) to pyruvate and NADH
NP_463742.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
NP_463743.1	lmo0212
NP_463744.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_463752.1	Type III pantothenate kinase; type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
NP_463759.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
NP_463764.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
NP_463766.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_463767.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
NP_463768.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
NP_463770.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
NP_463774.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NP_463775.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function
NP_463776.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
NP_463777.1	Modulates Rho-dependent transcription termination
NP_463778.1	lmo0247
NP_463779.1	binds directly to 23S ribosomal RNA
NP_463780.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
NP_463781.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
NP_463782.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
NP_463785.1	lmo0254
NP_463789.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
NP_463790.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_463796.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites.
NP_463801.1	lmo0270
NP_463804.1	lmo0273
NP_463805.1	lmo0274
NP_463810.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
NP_463812.1	lmo0281
NP_463817.1	produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however
NP_463824.1	SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
NP_463827.1	lmo0296
NP_463833.1	lmo0302
NP_463835.1	lmo0304
NP_463837.1	lmo0306
NP_463838.1	lmo0307
NP_463840.1	lmo0310
NP_463841.1	lmo0311
NP_463846.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
NP_463848.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
NP_463854.1	lmo0324
NP_463858.1	lmo0328
NP_463862.1	lmo0332
NP_463864.1	lmo0334
NP_463865.1	lmo0335
NP_463866.1	lmo0336
NP_463867.1	lmo0337
NP_463868.1	lmo0338
NP_463870.1	lmo0340
NP_463871.1	lmo0341
NP_463879.1	lmo0349
NP_463880.1	lmo0350
NP_463885.1	Reduces fumarate to succinate in anaerobic bacterial respiration
NP_463905.1	lmo0375
NP_463907.1	lmo0377
NP_463908.1	lmo0378
NP_463909.1	lmo0379
NP_463910.1	lmo0380
NP_463911.1	lmo0381
NP_463918.1	lmo0388
NP_463920.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_463921.1	lmo0391
NP_463923.1	lmo0393
NP_463926.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
NP_463933.1	lmo0403
NP_463934.1	lmo0404
NP_463937.1	lmo0407
NP_463938.1	lmo0408
NP_463940.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_463941.1	lmo0412
NP_463942.1	lmo0413
NP_463946.1	lmo0417
NP_463947.1	lmo0418
NP_463951.1	part of sigC operon that is induced by temperature upshift
NP_463952.1	part of sigC operon induced by temperature upshift
NP_463967.1	lmo0438
NP_463969.1	lmo0440
NP_463971.1	lmo0442
NP_463978.1	lmo0449
NP_463980.1	lmo0451
NP_463990.1	lmo0461
NP_463991.1	lmo0462
NP_463992.1	lmo0463
NP_463995.1	lmo0466
NP_463996.1	lmo0467
NP_463997.1	lmo0468
NP_463998.1	lmo0469
NP_464000.1	lmo0471
NP_464001.1	lmo0472
NP_464002.1	lmo0474
NP_464003.1	lmo0475
NP_464009.1	in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever
NP_464010.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
NP_464011.1	lmo0483
NP_464012.1	lmo0484; iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source
NP_464013.1	lmo0485
NP_464014.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
NP_464015.1	lmo0487
NP_464018.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_464019.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
NP_464032.1	lmo0504
NP_464038.1	lmo0510
NP_464040.1	lmo0512
NP_464053.1	lmo0525
NP_464056.1	hypothetical secreted protein
NP_464058.1	lmo0530
NP_464059.1	lmo0531
NP_464060.1	lmo0532
NP_464061.1	ACT domain-containing protein
NP_464067.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources
NP_464073.1	lmo0545
NP_464076.1	lmo0548
NP_464079.1	lmo0551
NP_464081.1	lmo0553
NP_464088.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
NP_464089.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
NP_464090.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
NP_464091.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
NP_464092.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
NP_464093.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
NP_464094.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
NP_464095.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
NP_464096.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
NP_464097.1	May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NP_464098.1	catalyzes the formation of L-histidinol from L-histidinol phosphate
NP_464100.1	lmo0572
NP_464104.1	hypothetical cell wall associated protein
NP_464105.1	lmo0577
NP_464110.1	iap; p60; autolytic enzyme; can cleave bacterial peptidoglycan; secreted by SecA2 system
NP_464111.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins
NP_464114.1	lmo0586
NP_464117.1	lmo0589
NP_464120.1	lmo0592
NP_464122.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
NP_464127.1	lmo0600
NP_464130.1	lmo0603
NP_464138.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
NP_464142.1	lmo0615
NP_464144.1	lmo0617
NP_464146.1	lmo0619
NP_464147.1	lmo0620
NP_464150.1	lmo0623
NP_464152.1	lmo0625
NP_464155.1	lmo0628
NP_464156.1	lmo0629
NP_464159.1	FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site
NP_464160.1	FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS
NP_464162.1	lmo0635
NP_464165.1	lmo0638
NP_464169.1	lmo0642
NP_464174.1	lmo0647
NP_464180.1	lmo0653
NP_464181.1	lmo0654
NP_464184.1	lmo0657
NP_464192.1	lmo0665
NP_464197.1	lmo0670
NP_464198.1	lmo0671
NP_464200.1	lmo0673
NP_464201.1	lmo0674
NP_464202.1	lmo0675
NP_464203.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
NP_464204.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
NP_464205.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
NP_464206.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
NP_464207.1	membrane protein involved in the flagellar export apparatus
NP_464208.1	Positive regulator of class III flagellar genes
NP_464209.1	makes up the distal portion of the flagellar basal body rod
NP_464211.1	lmo0684
NP_464212.1	With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.
NP_464214.1	lmo0687
NP_464217.1	structural flagella protein
NP_464221.1	lmo0694
NP_464222.1	lmo0695
NP_464223.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod
NP_464224.1	the hook connects flagellar basal body to the flagellar filament
NP_464225.1	One of three proteins involved in switching the direction of the flagellar rotation
NP_464226.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
NP_464227.1	One of three proteins involved in switching the direction of the flagellar rotation
NP_464228.1	lmo0701
NP_464229.1	lmo0702
NP_464230.1	lmo0703
NP_464231.1	lmo0704
NP_464232.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
NP_464233.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook
NP_464234.1	involved in flagellin assembly
NP_464236.1	lmo0709
NP_464237.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod
NP_464238.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
NP_464239.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
NP_464240.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
NP_464241.1	One of three proteins involved in switching the direction of the flagellar rotation
NP_464242.1	lmo0715; binds to and inhibits the function of flagella specific ATPase FliI
NP_464243.1	involved in type III protein export during flagellum assembly
NP_464245.1	lmo0718
NP_464247.1	lmo0720
NP_464249.1	catalyzes the formation of acetyl phosphate from pyruvate
NP_464254.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NP_464256.1	lmo0729
NP_464257.1	lmo0730
NP_464258.1	lmo0731
NP_464263.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
NP_464264.1	lmo0737
NP_464270.1	lmo0743
NP_464272.1	lmo0745
NP_464274.1	lmo0747
NP_464275.1	lmo0748
NP_464276.1	lmo0749
NP_464277.1	lmo0750
NP_464278.1	lmo0751
NP_464285.1	lmo0758
NP_464286.1	lmo0759
NP_464287.1	lmo0760
NP_464292.1	lmo0765
NP_464298.1	lmo0771
NP_464302.1	lmo0775
NP_464304.1	lmo0777
NP_464305.1	lmo0778
NP_464306.1	lmo0779
NP_464307.1	lmo0780
NP_464308.1	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel
NP_464315.1	lmo0788
NP_464318.1	lmo0791
NP_464324.1	lmo0797
NP_464326.1	lmo0799
NP_464331.1	lmo0804
NP_464332.1	lmo0805
NP_464339.1	lmo0812
NP_464346.1	lmo0819
NP_464348.1	lmo0821
NP_464351.1	lmo0824
NP_464358.1	lmo0831
NP_464361.1	lmo0834
NP_464364.1	cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate
NP_464366.1	lmo0840
NP_464375.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
NP_464377.1	lmo0851
NP_464381.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_464389.1	lmo0863
NP_464390.1	lmo0864
NP_464393.1	lmo0867
NP_464394.1	lmo0868
NP_464395.1	lmo0869
NP_464396.1	lmo0870
NP_464405.1	lmo0879
NP_464407.1	lmo0881
NP_464410.1	catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX
NP_464411.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
NP_464420.1	binds to sigma-B preventing the formation of an RNA polymerase holoenzyme
NP_464421.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase
NP_464426.1	lmo0900
NP_464430.1	lmo0904
NP_464431.1	lmo0905
NP_464432.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
NP_464436.1	lmo0910
NP_464437.1	lmo0911
NP_464448.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
NP_464453.1	responsible for recognizing base lesions in the genome and initiating base excision DNA repair
NP_464462.1	lmo0937
NP_464464.1	lmo0939
NP_464465.1	lmo0940
NP_464466.1	lmo0941
NP_464471.1	lmo0946
NP_464472.1	hypothetical transport protein
NP_464475.1	lmo0950
NP_464476.1	lmo0951
NP_464477.1	lmo0952
NP_464478.1	lmo0953
NP_464479.1	lmo0954
NP_464480.1	lmo0955
NP_464488.1	metalloprotease
NP_464491.1	lmo0966
NP_464493.1	catalyzes the phosphorylation of NAD to NADP
NP_464495.1	Catalyzes a key regulatory step in fatty acid biosynthesis
NP_464497.1	D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid
NP_464499.1	transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid
NP_464500.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
NP_464503.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
NP_464510.1	lmo0985
NP_464513.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
NP_464519.1	lmo0994
NP_464524.1	lmo0999
NP_464532.1	lmo1007
NP_464549.1	lmo1024
NP_464550.1	lmo1025
NP_464561.1	lmo1036
NP_464571.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
NP_464572.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
NP_464576.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_464579.1	Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA
NP_464580.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
NP_464581.1	lmo1056
NP_464584.1	lmo1059
NP_464593.1	lmo1068
NP_464597.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
NP_464611.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_464617.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
NP_464618.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
NP_464619.1	lmo1094
NP_464621.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
NP_464642.1	lmo1117
NP_464643.1	lmo1118
NP_464645.1	lmo1120
NP_464646.1	lmo1121
NP_464647.1	lmo1122
NP_464648.1	lmo1123
NP_464649.1	lmo1124
NP_464650.1	lmo1125
NP_464652.1	lmo1127
NP_464653.1	lmo1128
NP_464660.1	lmo1135
NP_464662.1	lmo1137
NP_464663.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
NP_464664.1	lmo1139
NP_464665.1	lmo1140
NP_464671.1	lmo1146
NP_464687.1	lmo1162
NP_464694.1	cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin
NP_464701.1	catalyzes the formation of acetaldehyde from ethanolamine
NP_464708.1	lmo1183
NP_464713.1	lmo1188
NP_464715.1	lmo1190
NP_464716.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
NP_464717.1	CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NP_464718.1	catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin
NP_464719.1	Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
NP_464720.1	catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a
NP_464721.1	catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating
NP_464723.1	catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3
NP_464724.1	catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine
NP_464728.1	catalyzes the formation of precorrin-3A from precorrin-2
NP_464729.2	catalyzes the ATP-dependent transport of cobalt
NP_464730.1	periplasmic cobalt binding component of the cobalt transport system
NP_464733.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NP_464739.1	lmo1214
NP_464744.1	lmo1219
NP_464746.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
NP_464747.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
NP_464752.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_464753.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
NP_464757.1	MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange
NP_464759.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NP_464760.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
NP_464762.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
NP_464764.1	hydrolyzes non-standard nucleotides such as xanthine and inosine
NP_464766.1	lmo1241
NP_464768.1	lmo1243
NP_464770.1	lmo1245
NP_464772.1	lmo1247
NP_464774.1	lmo1249
NP_464781.1	lmo1256
NP_464782.1	lmo1257
NP_464783.1	lmo1258
NP_464784.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
NP_464785.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
NP_464786.1	lmo1261
NP_464789.1	lmo1264
NP_464791.1	lmo1266
NP_464792.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
NP_464793.1	binds and unfolds substrates as part of the ClpXP protease
NP_464797.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
NP_464798.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
NP_464800.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
NP_464803.1	heat shock protein involved in degradation of misfolded proteins
NP_464804.1	heat shock protein involved in degradation of misfolded proteins
NP_464805.1	CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NP_464811.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_464812.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_464813.1	S-ribosylhomocysteine lyase; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
NP_464819.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
NP_464827.1	Represses a number of genes involved in the response to DNA damage
NP_464832.1	lmo1307
NP_464836.1	lmo1311
NP_464837.1	lmo1312
NP_464838.1	Catalyzes the phosphorylation of UMP to UDP
NP_464840.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
NP_464842.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
NP_464843.1	zinc metalloprotease Lmo1318
NP_464844.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_464845.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
NP_464847.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_464850.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_464852.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
NP_464853.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
NP_464855.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_464873.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
NP_464874.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein
NP_464875.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
NP_464876.1	lmo1351
NP_464877.1	lmo1352
NP_464884.1	Regulates rRNA biosynthesis by transcriptional antitermination
NP_464885.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
NP_464886.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
NP_464887.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
NP_464890.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
NP_464892.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
NP_464895.1	catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate
NP_464896.1	E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
NP_464901.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
NP_464904.1	involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site
NP_464905.1	lmo1380
NP_464906.1	lmo1381; catalyzes the hydrolysis of acylphosphate
NP_464907.1	lmo1382
NP_464908.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
NP_464912.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
NP_464923.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NP_464924.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
NP_464928.1	This protein performs the mismatch recognition step during the DNA repair process
NP_464929.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP_464935.1	lmo1410
NP_464936.1	lmo1411
NP_464941.1	lmo1416
NP_464945.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
NP_464948.1	lmo1423
NP_464957.1	lmo1432
NP_464960.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
NP_464961.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive
NP_464966.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
NP_464968.1	lmo1443
NP_464973.1	catalyzes the hydrolysis of pyrophosphate to phosphate
NP_464974.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
NP_464976.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
NP_464979.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium
NP_464983.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_464984.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_464985.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
NP_464986.1	lmo1461
NP_464987.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
NP_464994.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_464995.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
NP_464996.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
NP_464997.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
NP_464998.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
NP_464999.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
NP_465000.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NP_465001.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_465005.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
NP_465006.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
NP_465011.1	lmo1486
NP_465013.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
NP_465021.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_465022.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
NP_465028.1	lmo1503
NP_465029.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_465037.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
NP_465043.1	lmo1518
NP_465044.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
NP_465047.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
NP_465049.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
NP_465055.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
NP_465056.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
NP_465057.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
NP_465058.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
NP_465061.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
NP_465062.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_465063.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
NP_465065.1	involved in the peptidyltransferase reaction during translation
NP_465070.1	blocks the formation of polar Z-ring septums
NP_465072.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
NP_465073.1	functions in MreBCD complex in some organisms
NP_465074.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
NP_465077.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
NP_465078.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
NP_465079.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
NP_465080.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
NP_465081.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
NP_465082.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
NP_465084.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
NP_465085.1	Primosomal protein that may act to load helicase DnaC during DNA replication
NP_465088.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
NP_465089.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
NP_465090.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
NP_465091.1	Converts isocitrate to alpha ketoglutarate
NP_465092.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
NP_465094.1	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
NP_465095.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_465096.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_465097.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
NP_465098.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
NP_465102.1	catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins
NP_465106.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
NP_465108.1	antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
NP_465111.1	catalyzes the phosphorylation of NAD to NADP
NP_465112.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
NP_465114.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
NP_465115.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
NP_465116.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
NP_465117.1	Required for the synthesis of the thiazole moiety
NP_465119.1	acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation
NP_465122.1	lmo1597
NP_465125.1	catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NP_465130.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
NP_465140.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
NP_465151.1	lmo1626
NP_465152.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
NP_465153.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
NP_465154.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
NP_465155.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
NP_465156.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_465157.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
NP_465158.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
NP_465165.1	lmo1640
NP_465166.1	Catalyzes the conversion of citrate to isocitrate
NP_465168.1	lmo1643
NP_465173.1	lmo1648
NP_465174.1	lmo1649
NP_465181.1	lmo1656
NP_465182.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_465183.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_465184.1	lmo1659
NP_465189.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
NP_465190.1	lmo1665
NP_465197.1	converts O-succinylbenzoate to O-succinylbenzoyl-CoA
NP_465198.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
NP_465200.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
NP_465201.1	synthesizes isochorismate acid from chorismate
NP_465202.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
NP_465204.1	catalyzes the formation of L-homocysteine from cystathionine
NP_465206.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
NP_465210.1	converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate
NP_465213.1	Catalyzes a key regulatory step in fatty acid biosynthesis
NP_465217.1	lmo1692
NP_465218.1	Regulatory protein recX; binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
NP_465225.1	lmo1700
NP_465226.1	lmo1701
NP_465232.1	lmo1707
NP_465234.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
NP_465239.1	lmo1714
NP_465248.1	lmo1723
NP_465258.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
NP_465268.1	lmo1743
NP_465273.1	lmo1748
NP_465276.1	Uncharacterized RNA methyltransferase lmo1751
NP_465277.1	lmo1752
NP_465279.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
NP_465281.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
NP_465285.1	PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer
NP_465287.1	lmo1762
NP_465289.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
NP_465290.1	involved in de novo purine biosynthesis
NP_465292.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
NP_465293.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
NP_465294.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_465295.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_465296.1	With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway
NP_465297.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
NP_465298.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
NP_465299.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
NP_465300.1	Catalyzes a step in the de novo purine nucleotide biosynthetic pathway
NP_465304.1	lmo1779
NP_465305.1	catalyzes the release of the N-terminal amino acid from a tripeptide
NP_465306.1	lmo1781
NP_465308.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_465310.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
NP_465312.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_465316.1	lmo1791
NP_465317.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
NP_465318.1	Essential for efficient processing of 16S rRNA
NP_465322.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
NP_465330.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_465331.1	carries the fatty acid chain in fatty acid biosynthesis
NP_465334.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
NP_465335.1	negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria
NP_465336.1	catalyzes branch migration in Holliday junction intermediates
NP_465341.1	required for 70S ribosome assembly
NP_465343.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
NP_465344.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
NP_465349.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
NP_465351.1	lmo1826; Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NP_465352.1	Essential for recycling GMP and indirectly, cGMP
NP_465356.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_465357.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
NP_465358.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits
NP_465360.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
NP_465361.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
NP_465362.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
NP_465363.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
NP_465365.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
NP_465366.1	lmo1841
NP_465369.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
NP_465371.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
NP_465381.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
NP_465384.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
NP_465385.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
NP_465392.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_465399.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_465402.1	involved in manganese homeostasis; activates the transcription of the mntABCD operon
NP_465409.1	Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine
NP_465417.1	lmo1893
NP_465420.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_465421.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
NP_465423.1	unwinds DNA
NP_465424.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
NP_465425.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
NP_465426.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
NP_465429.1	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity
NP_465430.1	catalyzes the formation of methylglyoxal from glycerone phosphate
NP_465431.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
NP_465439.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
NP_465447.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
NP_465448.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
NP_465449.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
NP_465451.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
NP_465452.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
NP_465453.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
NP_465455.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
NP_465457.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
NP_465460.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
NP_465461.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
NP_465462.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
NP_465463.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
NP_465475.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB
NP_465477.1	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation
NP_465478.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
NP_465495.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_465499.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
NP_465502.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
NP_465504.1	lmo1980
NP_465507.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
NP_465509.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
NP_465510.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
NP_465511.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
NP_465512.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
NP_465513.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_465514.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
NP_465515.1	catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic
NP_465517.1	Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway
NP_465519.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
NP_465530.1	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase
NP_465542.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
NP_465543.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)
NP_465547.1	catalyzes the formation of oxaloacetate from L-aspartate
NP_465548.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
NP_465549.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
NP_465559.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
NP_465560.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
NP_465561.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP_465562.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
NP_465569.1	lmo2045
NP_465570.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
NP_465571.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
NP_465576.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
NP_465581.1	converts protoheme IX and farnesyl diphosphate to heme O
NP_465587.1	lmo2063
NP_465588.1	homopentamer; channel that opens in response to pressure or hypoosmotic shock
NP_465589.1	lmo2065
NP_465590.1	lmo2066
NP_465592.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_465593.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
NP_465595.1	lmo2071
NP_465596.1	modulates transcription in response to the NADH/NAD(+) redox state
NP_465603.1	lmo2079
NP_465604.1	lmo2080
NP_465605.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
NP_465606.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
NP_465607.1	lmo2083
NP_465608.1	lmo2084
NP_465614.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
NP_465615.1	catalyzes the formation of arginine from (N-L-arginino)succinate
NP_465617.1	lmo2093
NP_465625.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
NP_465626.1	lmo2102; with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
NP_465627.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
NP_465628.1	lmo2104
NP_465636.1	lmo2112
NP_465640.1	lmo2116
NP_465642.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP_465651.1	lmo2127
NP_465653.1	lmo2129
NP_465655.1	lmo2131
NP_465656.1	lmo2132
NP_465666.1	lmo2142
NP_465674.1	lmo2150
NP_465677.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_465678.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
NP_465679.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_465680.1	lmo2156
NP_465685.1	lmo2161
NP_465690.1	lmo2166
NP_465693.1	lmo2169
NP_465699.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NP_465709.1	lmo2185
NP_465710.1	lmo2186
NP_465711.1	lmo2187
NP_465714.1	enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence
NP_465720.1	peptide ABC transporter substrate-binding protein
NP_465721.1	lmo2197
NP_465722.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_465726.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
NP_465733.1	lmo2209
NP_465734.1	lmo2210
NP_465735.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
NP_465736.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
NP_465742.1	lmo2218
NP_465744.1	catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates
NP_465749.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
NP_465760.1	catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_465763.1	lmo2239
NP_465776.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
NP_465779.1	lmo2255
NP_465782.1	lmo2258
NP_465793.2	lmo2269
NP_465795.1	lmo2271
NP_465796.1	lmo2272
NP_465798.1	protein gp29 [Bacteriophage A118]
NP_465799.1	Portein gp28 [Bacteriophage A118]
NP_465801.1	lmo2277
NP_465803.1	holin [Bacteriophage A118]
NP_465804.1	protein gp23 [Bacteriophage A118]
NP_465805.1	protein gp22 [Bacteriophage A118]
NP_465806.1	protein gp21 [Bacteriophage A118]
NP_465807.1	protein gp20 [Bacteriophage A118]
NP_465808.1	Protein gp19 [Bacteriophage A118]
NP_465809.1	Protein gp18 [Bacteriophage A118]
NP_465810.1	Protein gp17 [Bacteriophage A118]
NP_465811.1	tape-measure [Bacteriophage A118]
NP_465812.1	Protein gp15 [Bacteriophage A118]
NP_465813.1	Protein gp14 [Bacteriophage A118]
NP_465814.1	Portein gp13 [Bacteriophage A118]
NP_465815.1	major tail shaft protein [Bacteriophage A118]
NP_465816.1	Portein gp11 [Bacteriophage A118]
NP_465817.1	Protein gp10 [Bacteriophage A118]
NP_465818.1	Protein gp9 [Bacteriophage A118]
NP_465819.1	Protein gp8 [Bacteriophage A118]
NP_465822.1	Protein gp4 [Bacteriophage A118]
NP_465823.1	portal protein [Bacteriophage A118]
NP_465826.1	lmo2302
NP_465829.1	lmo2305
NP_465833.1	lmo2309
NP_465834.1	lmo2310
NP_465835.1	lmo2311
NP_465836.1	lmo2312
NP_465838.1	lmo2314
NP_465842.1	lmo2318
NP_465844.1	lmo2320
NP_465845.1	lmo2321
NP_465846.1	gp44 [Bacteriophage A118]
NP_465847.1	gp43 [Bacteriophage A118]
NP_465849.1	lmo2325
NP_465851.1	lmo2327
NP_465856.1	integrase [Bacteriophage A118]
NP_465879.1	lmo2356
NP_465890.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
NP_465891.1	lmo2368
NP_465892.1	induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation
NP_465897.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive
NP_465898.1	lmo2375
NP_465901.1	subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_465902.1	subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport
NP_465903.1	subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_465904.1	subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone
NP_465905.1	subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_465906.1	subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_465907.1	subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_465918.1	lmo2395
NP_465928.1	lmo2405
NP_465930.1	lmo2407
NP_465932.1	lmo2409
NP_465933.1	lmo2410
NP_465939.1	lmo2416
NP_465943.1	lmo2420
NP_465948.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
NP_465955.1	lmo2432
NP_465960.1	lmo2437
NP_465961.1	lmo2438
NP_465962.1	lmo2439
NP_465963.1	lmo2440
NP_465965.1	lmo2442
NP_465966.1	lmo2443
NP_465971.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_465977.1	lmo2454
NP_465978.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
NP_465979.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP_465980.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
NP_465981.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
NP_465982.1	catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate
NP_465984.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
NP_465988.1	lmo2465
NP_465989.1	lmo2466
NP_465991.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
NP_465994.1	catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds
NP_466002.1	lmo2479
NP_466004.1	hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation
NP_466005.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_466006.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
NP_466009.1	lmo2486
NP_466011.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP_466012.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
NP_466014.1	lmo2491
NP_466015.1	lmo2492
NP_466018.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
NP_466019.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
NP_466025.1	lmo2502
NP_466032.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism
NP_466033.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
NP_466040.1	lmo2517
NP_466047.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
NP_466049.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_466051.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
NP_466052.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_466053.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
NP_466054.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_466055.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
NP_466056.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
NP_466057.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
NP_466058.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_466061.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
NP_466062.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
NP_466066.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1
NP_466067.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
NP_466068.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
NP_466069.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
NP_466070.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
NP_466074.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
NP_466075.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_466082.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_466083.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NP_466084.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
NP_466085.1	lmo2562
NP_466089.1	lmo2566
NP_466090.1	lmo2567
NP_466091.1	lmo2568
NP_466093.1	lmo2570
NP_466097.1	lmo2574
NP_466101.1	lmo2578
NP_466107.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
NP_466117.1	lmo2594
NP_466119.1	forms a direct contact with the tRNA during translation
NP_466120.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_466121.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
NP_466123.1	with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene
NP_466124.1	with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene
NP_466126.1	lmo2603
NP_466127.1	lmo2604
NP_466128.1	is a component of the macrolide binding site in the peptidyl transferase center
NP_466129.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_466130.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_466131.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_466132.1	smallest protein in the large subunit; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
NP_466133.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
NP_466134.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
NP_466135.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_466137.1	L30 binds domain II of the 23S rRNA and the 5S rRNA
NP_466138.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
NP_466139.1	binds 5S rRNA along with protein L5 and L25
NP_466140.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_466141.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP_466143.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_466144.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
NP_466145.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_466146.1	primary binding protein; helps mediate assembly; involved in translation fidelity
NP_466147.1	one of the stabilizing components for the large ribosomal subunit
NP_466149.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
NP_466150.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
NP_466151.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP_466152.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_466153.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
NP_466154.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_466155.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
NP_466156.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_466158.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
NP_466162.1	lmo2639
NP_466163.1	lmo2640
NP_466165.1	lmo2642
NP_466166.1	lmo2643
NP_466167.1	lmo2644
NP_466168.1	lmo2646
NP_466171.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_466175.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_466176.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
NP_466177.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_466178.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_466179.1	dGTPase type 3 subfamily, presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
NP_466191.1	lmo2669
NP_466193.1	lmo2671
NP_466196.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
NP_466197.1	lmo2675
NP_466203.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_466204.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_466208.1	lmo2686
NP_466213.1	cell wall hydrolase; muramidase-2 like protein in Enterococcus faecalis; in Enterococcus faecalis a mutant in this gene has no effect on virulence in mouse models; Listeria monocytogenes MurA in involved in general autolysis; contains an N-terminal muramidase domain and C-terminal LysM repeats for cell wall-anchoring
NP_466214.1	lmo2692
NP_466215.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
NP_466217.1	with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase
NP_466224.1	involved in a recombinational process of DNA repair, independent of the recBC complex
NP_466227.1	lmo2705
NP_466228.1	lmo2706
NP_466229.1	lmo2707
NP_466231.1	lmo2709
NP_466232.1	lmo2710
NP_466254.1	lmo2732
NP_466261.1	Modulates the activities of several enzymes which are inactive in their acetylated form
NP_466262.1	lmo2740
NP_466264.1	lmo2742
NP_466268.1	lmo2746
NP_466269.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_466275.1	lmo2753
NP_466278.1	decatenates replicating daughter chromosomes
NP_466289.1	lmo2767
NP_466290.1	hypothetical membrane protein
NP_466292.1	Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine
NP_466298.1	lmo2776
NP_466300.1	lmo2778
NP_466311.1	lmo2789
NP_466314.1	lmo2792
NP_466315.1	lmo2793
NP_466323.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_466324.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
NP_466325.1	lmo2803
NP_466326.1	lmo2804
NP_466327.1	hypothetical secreted protein
NP_466328.1	hypothetical secreted protein
NP_466329.1	hypothetical secreted protein
NP_466330.1	hypothetical secreted protein
NP_466331.1	hypothetical secreted protein
NP_466332.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_466333.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_466335.1	lmo2813
NP_466337.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NP_466344.1	lmo2822
NP_466347.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
NP_466350.1	lmo2828
NP_466365.1	lmo2843
NP_466370.1	catalyzes the formation of L-rhamnulose from L-rhamnose
NP_466374.1	lmo2852
NP_466377.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
NP_466378.1	in Escherichia coli transcription of this gene is enhanced by polyamines