-- dump date   	20140619_134218
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
879088000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
879088000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
879088000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088000004	Walker A motif; other site
879088000005	ATP binding site [chemical binding]; other site
879088000006	Walker B motif; other site
879088000007	arginine finger; other site
879088000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
879088000009	DnaA box-binding interface [nucleotide binding]; other site
879088000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
879088000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
879088000012	putative DNA binding surface [nucleotide binding]; other site
879088000013	dimer interface [polypeptide binding]; other site
879088000014	beta-clamp/clamp loader binding surface; other site
879088000015	beta-clamp/translesion DNA polymerase binding surface; other site
879088000016	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
879088000017	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
879088000018	S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988
879088000019	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
879088000020	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
879088000021	Walker A/P-loop; other site
879088000022	ATP binding site [chemical binding]; other site
879088000023	Q-loop/lid; other site
879088000024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088000025	ABC transporter signature motif; other site
879088000026	Walker B; other site
879088000027	D-loop; other site
879088000028	H-loop/switch region; other site
879088000029	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
879088000030	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088000031	Mg2+ binding site [ion binding]; other site
879088000032	G-X-G motif; other site
879088000033	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
879088000034	anchoring element; other site
879088000035	dimer interface [polypeptide binding]; other site
879088000036	ATP binding site [chemical binding]; other site
879088000037	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
879088000038	active site
879088000039	putative metal-binding site [ion binding]; other site
879088000040	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
879088000041	DNA gyrase subunit A; Validated; Region: PRK05560
879088000042	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
879088000043	CAP-like domain; other site
879088000044	active site
879088000045	primary dimer interface [polypeptide binding]; other site
879088000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088000051	cardiolipin synthetase; Reviewed; Region: PRK12452
879088000052	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
879088000053	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
879088000054	putative active site [active]
879088000055	catalytic site [active]
879088000056	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
879088000057	putative active site [active]
879088000058	catalytic site [active]
879088000059	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
879088000060	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088000061	Coenzyme A binding pocket [chemical binding]; other site
879088000062	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
879088000063	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
879088000064	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
879088000065	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
879088000066	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
879088000067	SH3-like domain; Region: SH3_8; pfam13457
879088000068	SH3-like domain; Region: SH3_8; pfam13457
879088000069	SH3-like domain; Region: SH3_8; pfam13457
879088000070	cytochrome aa3 quinol oxidase, subunit II; Region: QOXA; TIGR01432
879088000071	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
879088000072	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
879088000073	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
879088000074	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
879088000075	D-pathway; other site
879088000076	Putative ubiquinol binding site [chemical binding]; other site
879088000077	Low-spin heme (heme b) binding site [chemical binding]; other site
879088000078	Putative water exit pathway; other site
879088000079	Binuclear center (heme o3/CuB) [ion binding]; other site
879088000080	K-pathway; other site
879088000081	Putative proton exit pathway; other site
879088000082	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
879088000083	Subunit I/III interface [polypeptide binding]; other site
879088000084	Subunit III/IV interface [polypeptide binding]; other site
879088000085	cytochrome aa3 quinol oxidase, subunit IV; Region: QoxD; TIGR02901
879088000086	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
879088000087	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
879088000088	putative active site [active]
879088000089	putative metal binding site [ion binding]; other site
879088000090	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
879088000091	beta-galactosidase; Region: BGL; TIGR03356
879088000092	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
879088000093	Bacterial SH3 domain; Region: SH3_3; pfam08239
879088000094	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
879088000095	putative active site [active]
879088000096	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088000097	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088000098	DNA-binding site [nucleotide binding]; DNA binding site
879088000099	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
879088000100	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088000101	active site
879088000102	active pocket/dimerization site; other site
879088000103	phosphorylation site [posttranslational modification]
879088000104	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
879088000105	active site
879088000106	phosphorylation site [posttranslational modification]
879088000107	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
879088000108	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
879088000109	hypothetical protein; Provisional; Region: PRK02947
879088000110	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088000111	putative active site [active]
879088000112	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
879088000113	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
879088000114	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
879088000115	active site turn [active]
879088000116	phosphorylation site [posttranslational modification]
879088000117	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
879088000118	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
879088000119	HPr interaction site; other site
879088000120	glycerol kinase (GK) interaction site [polypeptide binding]; other site
879088000121	active site
879088000122	phosphorylation site [posttranslational modification]
879088000123	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
879088000124	putative dimer interface [polypeptide binding]; other site
879088000125	catalytic triad [active]
879088000126	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088000127	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
879088000128	Walker A/P-loop; other site
879088000129	ATP binding site [chemical binding]; other site
879088000130	Q-loop/lid; other site
879088000131	ABC transporter signature motif; other site
879088000132	Walker B; other site
879088000133	D-loop; other site
879088000134	H-loop/switch region; other site
879088000135	Protein of unknown function (DUF2705); Region: DUF2705; pfam10920
879088000136	Protein of unknown function (DUF2712); Region: DUF2712; pfam10916
879088000137	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088000138	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000139	active site
879088000140	motif I; other site
879088000141	motif II; other site
879088000142	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000143	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088000144	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088000145	DNA binding site [nucleotide binding]
879088000146	domain linker motif; other site
879088000147	Ligand-binding domain of DNA-binding regulatory protein from Corynebacterium glutamicum which has a unique ability to produce significant amounts of L-glutamate directly from cheap sugar and ammonia; Region: PBP1_LacI_like_13; cd06299
879088000148	dimerization interface [polypeptide binding]; other site
879088000149	putative ligand binding site [chemical binding]; other site
879088000150	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088000151	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088000152	nucleotide binding site [chemical binding]; other site
879088000153	Butyrate kinase [Energy production and conversion]; Region: COG3426
879088000154	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
879088000155	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
879088000156	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088000157	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088000158	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
879088000159	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
879088000160	dimer interface [polypeptide binding]; other site
879088000161	active site
879088000162	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
879088000163	dimer interface [polypeptide binding]; other site
879088000164	active site
879088000165	putrescine carbamoyltransferase; Provisional; Region: PRK02255
879088000166	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
879088000167	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
879088000168	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
879088000169	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
879088000170	agmatine deiminase; Provisional; Region: PRK13551
879088000171	agmatine deiminase; Region: agmatine_aguA; TIGR03380
879088000172	carbamate kinase; Reviewed; Region: PRK12686
879088000173	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
879088000174	putative substrate binding site [chemical binding]; other site
879088000175	nucleotide binding site [chemical binding]; other site
879088000176	nucleotide binding site [chemical binding]; other site
879088000177	homodimer interface [polypeptide binding]; other site
879088000178	agmatine deiminase; Provisional; Region: PRK13551
879088000179	agmatine deiminase; Region: agmatine_aguA; TIGR03380
879088000180	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088000181	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088000182	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088000183	putative active site [active]
879088000184	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
879088000185	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
879088000186	arginine deiminase; Provisional; Region: PRK01388
879088000187	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
879088000188	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
879088000189	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
879088000190	dimer interface [polypeptide binding]; other site
879088000191	ssDNA binding site [nucleotide binding]; other site
879088000192	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088000193	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
879088000194	Predicted membrane protein [Function unknown]; Region: COG3212
879088000195	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
879088000196	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
879088000197	putative accessory gene regulator protein; Provisional; Region: PRK01100
879088000198	Staphylococcal AgrD protein; Region: AgrD; cl05477
879088000199	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
879088000200	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088000201	ATP binding site [chemical binding]; other site
879088000202	Mg2+ binding site [ion binding]; other site
879088000203	G-X-G motif; other site
879088000204	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
879088000205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088000206	active site
879088000207	phosphorylation site [posttranslational modification]
879088000208	intermolecular recognition site; other site
879088000209	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
879088000210	LytTr DNA-binding domain; Region: LytTR; pfam04397
879088000211	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
879088000212	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
879088000213	DHH family; Region: DHH; pfam01368
879088000214	DHHA1 domain; Region: DHHA1; pfam02272
879088000215	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
879088000216	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
879088000217	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
879088000218	replicative DNA helicase; Provisional; Region: PRK05748
879088000219	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
879088000220	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
879088000221	Walker A motif; other site
879088000222	ATP binding site [chemical binding]; other site
879088000223	Walker B motif; other site
879088000224	DNA binding loops [nucleotide binding]
879088000225	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
879088000226	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
879088000227	GDP-binding site [chemical binding]; other site
879088000228	ACT binding site; other site
879088000229	IMP binding site; other site
879088000230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842
879088000231	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
879088000232	type VII secretion protein EsaA, N-terminal domain; Region: T7_esaA_Nterm; TIGR03929
879088000233	Predicted membrane protein [Function unknown]; Region: COG1511
879088000234	Predicted membrane protein (DUF2085); Region: DUF2085; pfam09858
879088000235	WXG100 protein secretion system (Wss), protein EssA; Region: EssA; cl11266
879088000236	Uncharacterized small protein [Function unknown]; Region: COG5417
879088000237	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; cl01868
879088000238	type VII secretion protein EssB; Region: T7_EssB; TIGR03926
879088000239	DNA transporter; Region: FtsK_SpoIIIE_N; pfam12538
879088000240	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
879088000241	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
879088000242	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
879088000243	Proteins of 100 residues with WXG; Region: WXG100; pfam06013
879088000244	Uncharacterized conserved protein [Function unknown]; Region: COG5444
879088000245	Protein of unknown function (DUF4237); Region: DUF4237; pfam14021
879088000246	Uncharacterized conserved protein [Function unknown]; Region: COG5444
879088000247	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
879088000248	Protein of unknown function (DUF4237); Region: DUF4237; pfam14021
879088000249	Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; COG1377
879088000250	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
879088000251	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
879088000252	tetramer interface [polypeptide binding]; other site
879088000253	active site
879088000254	Mg2+/Mn2+ binding site [ion binding]; other site
879088000255	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
879088000256	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
879088000257	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
879088000258	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
879088000259	DNA binding site [nucleotide binding]
879088000260	active site
879088000261	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
879088000262	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
879088000263	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
879088000264	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
879088000265	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178
879088000266	putative ligand binding site [chemical binding]; other site
879088000267	putative NAD binding site [chemical binding]; other site
879088000268	catalytic site [active]
879088000269	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088000270	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088000271	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088000272	DNA binding residues [nucleotide binding]
879088000273	putative dimer interface [polypeptide binding]; other site
879088000274	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088000275	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088000276	active site
879088000277	catalytic tetrad [active]
879088000278	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000279	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088000280	ATP synthase subunit C; Region: ATP-synt_C; cl00466
879088000281	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
879088000282	F0F1 ATP synthase subunit alpha; Provisional; Region: PRK13343
879088000283	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
879088000284	Walker A motif; other site
879088000285	ATP binding site [chemical binding]; other site
879088000286	Walker B motif; other site
879088000287	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
879088000288	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
879088000289	core domain interface [polypeptide binding]; other site
879088000290	delta subunit interface [polypeptide binding]; other site
879088000291	epsilon subunit interface [polypeptide binding]; other site
879088000292	F0F1 ATP synthase subunit beta; Provisional; Region: PRK12597
879088000293	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
879088000294	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
879088000295	alpha subunit interaction interface [polypeptide binding]; other site
879088000296	Walker A motif; other site
879088000297	ATP binding site [chemical binding]; other site
879088000298	Walker B motif; other site
879088000299	inhibitor binding site; inhibition site
879088000300	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
879088000301	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
879088000302	gamma subunit interface [polypeptide binding]; other site
879088000303	epsilon subunit interface [polypeptide binding]; other site
879088000304	LBP interface [polypeptide binding]; other site
879088000305	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
879088000306	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088000307	active pocket/dimerization site; other site
879088000308	active site
879088000309	phosphorylation site [posttranslational modification]
879088000310	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
879088000311	active site
879088000312	phosphorylation site [posttranslational modification]
879088000313	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
879088000314	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
879088000315	Domain of unknown function (DUF956); Region: DUF956; pfam06115
879088000316	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
879088000317	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
879088000318	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
879088000319	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088000320	dimerization interface [polypeptide binding]; other site
879088000321	putative DNA binding site [nucleotide binding]; other site
879088000322	Uncharacterized conserved protein [Function unknown]; Region: COG1359
879088000323	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
879088000324	dimer interface [polypeptide binding]; other site
879088000325	FMN binding site [chemical binding]; other site
879088000326	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
879088000327	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
879088000328	active site
879088000329	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
879088000330	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
879088000331	Interdomain contacts; other site
879088000332	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
879088000333	aromatic chitin/cellulose binding site residues [chemical binding]; other site
879088000334	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088000335	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088000336	nucleotide binding site [chemical binding]; other site
879088000337	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088000338	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088000339	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
879088000340	Walker A/P-loop; other site
879088000341	ATP binding site [chemical binding]; other site
879088000342	Q-loop/lid; other site
879088000343	ABC transporter signature motif; other site
879088000344	Walker B; other site
879088000345	D-loop; other site
879088000346	H-loop/switch region; other site
879088000347	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088000348	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088000349	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
879088000350	Walker A/P-loop; other site
879088000351	ATP binding site [chemical binding]; other site
879088000352	Q-loop/lid; other site
879088000353	ABC transporter signature motif; other site
879088000354	Walker B; other site
879088000355	D-loop; other site
879088000356	H-loop/switch region; other site
879088000357	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
879088000358	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088000359	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088000360	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088000361	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
879088000362	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
879088000363	substrate binding pocket [chemical binding]; other site
879088000364	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
879088000365	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
879088000366	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000367	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
879088000368	ligand binding site [chemical binding]; other site
879088000369	flexible hinge region; other site
879088000370	Domain of unknown function (DUF955); Region: DUF955; pfam06114
879088000371	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088000372	non-specific DNA binding site [nucleotide binding]; other site
879088000373	salt bridge; other site
879088000374	sequence-specific DNA binding site [nucleotide binding]; other site
879088000375	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
879088000376	Predicted secreted protein [Function unknown]; Region: COG5437
879088000377	Phage-related protein [Function unknown]; Region: COG5412
879088000378	Phage tail protein; Region: Sipho_tail; pfam05709
879088000379	Prophage endopeptidase tail; Region: Prophage_tail; pfam06605
879088000380	Phage-related holin (Lysis protein) [General function prediction only]; Region: COG4824
879088000381	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
879088000382	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
879088000383	active site
879088000384	metal binding site [ion binding]; metal-binding site
879088000385	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
879088000386	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
879088000387	putative active site [active]
879088000388	putative metal binding site [ion binding]; other site
879088000389	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
879088000390	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
879088000391	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
879088000392	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
879088000393	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
879088000394	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
879088000395	active site
879088000396	Uncharacterized conserved protein [Function unknown]; Region: COG3592
879088000397	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088000398	Coenzyme A binding pocket [chemical binding]; other site
879088000399	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
879088000400	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
879088000401	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
879088000402	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000403	dimer interface [polypeptide binding]; other site
879088000404	conserved gate region; other site
879088000405	putative PBP binding loops; other site
879088000406	ABC-ATPase subunit interface; other site
879088000407	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
879088000408	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
879088000409	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000410	dimer interface [polypeptide binding]; other site
879088000411	conserved gate region; other site
879088000412	putative PBP binding loops; other site
879088000413	ABC-ATPase subunit interface; other site
879088000414	Protein of unknown function (DUF3130; Region: DUF3130; cl12867
879088000415	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088000416	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088000417	ADP-ribosyl cyclase, also known as cyclic ADP-ribose hydrolase or CD38; Region: Rib_hydrolase; cl08346
879088000418	phosphoenolpyruvate synthase; Validated; Region: PRK06464
879088000419	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
879088000420	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
879088000421	peptide binding site [polypeptide binding]; other site
879088000422	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
879088000423	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
879088000424	metal binding site [ion binding]; metal-binding site
879088000425	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
879088000426	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
879088000427	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
879088000428	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088000429	ABC-ATPase subunit  interface; other site
879088000430	dimer interface [polypeptide binding]; other site
879088000431	putative PBP binding regions; other site
879088000432	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
879088000433	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000434	ligand binding site [chemical binding]; other site
879088000435	flexible hinge region; other site
879088000436	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
879088000437	DEAD_2; Region: DEAD_2; pfam06733
879088000438	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
879088000439	sugar phosphate phosphatase; Provisional; Region: PRK10513
879088000440	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000441	active site
879088000442	motif I; other site
879088000443	motif II; other site
879088000444	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000445	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
879088000446	Collagen binding domain; Region: Collagen_bind; pfam05737
879088000447	Cna protein B-type domain; Region: Cna_B; pfam05738
879088000448	Cna protein B-type domain; Region: Cna_B; pfam05738
879088000449	Cna protein B-type domain; Region: Cna_B; pfam05738
879088000450	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
879088000451	Collagen binding domain; Region: Collagen_bind; pfam05737
879088000452	Cna protein B-type domain; Region: Cna_B; pfam05738
879088000453	Cna protein B-type domain; Region: Cna_B; pfam05738
879088000454	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088000455	DNA polymerase III subunit delta'; Validated; Region: PRK08058
879088000456	DNA polymerase III subunit delta'; Validated; Region: PRK08485
879088000457	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
879088000458	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467
879088000459	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
879088000460	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088000461	S-adenosylmethionine binding site [chemical binding]; other site
879088000462	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
879088000463	GIY-YIG motif/motif A; other site
879088000464	putative active site [active]
879088000465	putative metal binding site [ion binding]; other site
879088000466	Predicted methyltransferases [General function prediction only]; Region: COG0313
879088000467	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
879088000468	putative SAM binding site [chemical binding]; other site
879088000469	putative homodimer interface [polypeptide binding]; other site
879088000470	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
879088000471	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
879088000472	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
879088000473	Uncharacterized conserved protein [Function unknown]; Region: COG5361
879088000474	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
879088000475	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
879088000476	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088000477	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
879088000478	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
879088000479	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
879088000480	active site
879088000481	HIGH motif; other site
879088000482	KMSKS motif; other site
879088000483	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
879088000484	tRNA binding surface [nucleotide binding]; other site
879088000485	anticodon binding site; other site
879088000486	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
879088000487	dimer interface [polypeptide binding]; other site
879088000488	putative tRNA-binding site [nucleotide binding]; other site
879088000489	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
879088000490	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088000491	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088000492	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
879088000493	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
879088000494	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000495	dimer interface [polypeptide binding]; other site
879088000496	conserved gate region; other site
879088000497	putative PBP binding loops; other site
879088000498	ABC-ATPase subunit interface; other site
879088000499	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088000500	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000501	dimer interface [polypeptide binding]; other site
879088000502	conserved gate region; other site
879088000503	putative PBP binding loops; other site
879088000504	ABC-ATPase subunit interface; other site
879088000505	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
879088000506	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088000507	alpha-glucosidase; Provisional; Region: PRK10426
879088000508	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
879088000509	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
879088000510	active site
879088000511	catalytic site [active]
879088000512	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
879088000513	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
879088000514	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
879088000515	trimer interface [polypeptide binding]; other site
879088000516	active site
879088000517	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
879088000518	catalytic site [active]
879088000519	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
879088000520	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
879088000521	active site
879088000522	catalytic site [active]
879088000523	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
879088000524	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
879088000525	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
879088000526	active site
879088000527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3583
879088000528	Domain of unknown function (DUF348); Region: DUF348; pfam03990
879088000529	Domain of unknown function (DUF348); Region: DUF348; pfam03990
879088000530	G5 domain; Region: G5; pfam07501
879088000531	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
879088000532	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
879088000533	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
879088000534	putative active site [active]
879088000535	putative metal binding site [ion binding]; other site
879088000536	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
879088000537	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
879088000538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088000539	S-adenosylmethionine binding site [chemical binding]; other site
879088000540	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
879088000541	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
879088000542	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
879088000543	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
879088000544	putative active site [active]
879088000545	YdjC motif; other site
879088000546	Mg binding site [ion binding]; other site
879088000547	putative homodimer interface [polypeptide binding]; other site
879088000548	pur operon repressor; Provisional; Region: PRK09213
879088000549	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
879088000550	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088000551	active site
879088000552	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
879088000553	HlyD family secretion protein; Region: HlyD_3; pfam13437
879088000554	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088000555	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088000556	Walker A/P-loop; other site
879088000557	ATP binding site [chemical binding]; other site
879088000558	Q-loop/lid; other site
879088000559	ABC transporter signature motif; other site
879088000560	Walker B; other site
879088000561	D-loop; other site
879088000562	H-loop/switch region; other site
879088000563	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088000564	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088000565	FtsX-like permease family; Region: FtsX; pfam02687
879088000566	regulatory protein SpoVG; Reviewed; Region: PRK13259
879088000567	regulatory protein SpoVG; Reviewed; Region: PRK13259
879088000568	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
879088000569	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
879088000570	Substrate binding site; other site
879088000571	Mg++ binding site; other site
879088000572	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
879088000573	active site
879088000574	substrate binding site [chemical binding]; other site
879088000575	CoA binding site [chemical binding]; other site
879088000576	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
879088000577	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
879088000578	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088000579	active site
879088000580	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000581	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088000582	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088000583	Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C; Region: PI-PLCc; cd00137
879088000584	active site
879088000585	catalytic site [active]
879088000586	Thiol-activated cytolysin; Region: Thiol_cytolysin; pfam01289
879088000587	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
879088000588	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
879088000589	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
879088000590	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
879088000591	active site
879088000592	Zn binding site [ion binding]; other site
879088000593	ActA Protein; Region: ActA; pfam05058
879088000594	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
879088000595	Zn binding site [ion binding]; other site
879088000596	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
879088000597	hypothetical protein; Provisional; Region: PRK01119
879088000598	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
879088000599	A new structural DNA glycosylase; Region: AlkD_like; cd06561
879088000600	active site
879088000601	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
879088000602	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
879088000603	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088000604	NAD binding site [chemical binding]; other site
879088000605	dimer interface [polypeptide binding]; other site
879088000606	substrate binding site [chemical binding]; other site
879088000607	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
879088000608	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
879088000609	5S rRNA interface [nucleotide binding]; other site
879088000610	CTC domain interface [polypeptide binding]; other site
879088000611	L16 interface [polypeptide binding]; other site
879088000612	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088000613	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088000614	Coenzyme A binding pocket [chemical binding]; other site
879088000615	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
879088000616	putative active site [active]
879088000617	catalytic residue [active]
879088000618	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
879088000619	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
879088000620	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088000621	ATP binding site [chemical binding]; other site
879088000622	putative Mg++ binding site [ion binding]; other site
879088000623	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088000624	nucleotide binding region [chemical binding]; other site
879088000625	ATP-binding site [chemical binding]; other site
879088000626	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
879088000627	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
879088000628	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
879088000629	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088000630	RNA binding surface [nucleotide binding]; other site
879088000631	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
879088000632	Septum formation initiator; Region: DivIC; pfam04977
879088000633	hypothetical protein; Provisional; Region: PRK08582
879088000634	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
879088000635	RNA binding site [nucleotide binding]; other site
879088000636	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
879088000637	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
879088000638	Ligand Binding Site [chemical binding]; other site
879088000639	TilS substrate C-terminal domain; Region: TilS_C; smart00977
879088000640	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
879088000641	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088000642	active site
879088000643	FtsH Extracellular; Region: FtsH_ext; pfam06480
879088000644	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
879088000645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088000646	Walker A motif; other site
879088000647	ATP binding site [chemical binding]; other site
879088000648	Walker B motif; other site
879088000649	arginine finger; other site
879088000650	Peptidase family M41; Region: Peptidase_M41; pfam01434
879088000651	pantothenate kinase; Reviewed; Region: PRK13318
879088000652	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
879088000653	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
879088000654	dimerization interface [polypeptide binding]; other site
879088000655	domain crossover interface; other site
879088000656	redox-dependent activation switch; other site
879088000657	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
879088000658	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
879088000659	dimer interface [polypeptide binding]; other site
879088000660	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088000661	catalytic residue [active]
879088000662	dihydropteroate synthase; Region: DHPS; TIGR01496
879088000663	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
879088000664	substrate binding pocket [chemical binding]; other site
879088000665	dimer interface [polypeptide binding]; other site
879088000666	inhibitor binding site; inhibition site
879088000667	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
879088000668	homooctamer interface [polypeptide binding]; other site
879088000669	active site
879088000670	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
879088000671	catalytic center binding site [active]
879088000672	ATP binding site [chemical binding]; other site
879088000673	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
879088000674	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
879088000675	FMN binding site [chemical binding]; other site
879088000676	active site
879088000677	catalytic residues [active]
879088000678	substrate binding site [chemical binding]; other site
879088000679	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
879088000680	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
879088000681	dimer interface [polypeptide binding]; other site
879088000682	putative anticodon binding site; other site
879088000683	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
879088000684	motif 1; other site
879088000685	active site
879088000686	motif 2; other site
879088000687	motif 3; other site
879088000688	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
879088000689	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
879088000690	Arginine kinase [Amino acid transport and metabolism]; Region: COG3869
879088000691	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
879088000692	ADP binding site [chemical binding]; other site
879088000693	phosphagen binding site; other site
879088000694	substrate specificity loop; other site
879088000695	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
879088000696	Clp amino terminal domain; Region: Clp_N; pfam02861
879088000697	Clp amino terminal domain; Region: Clp_N; pfam02861
879088000698	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088000699	Walker A motif; other site
879088000700	ATP binding site [chemical binding]; other site
879088000701	Walker B motif; other site
879088000702	arginine finger; other site
879088000703	UvrB/uvrC motif; Region: UVR; pfam02151
879088000704	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088000705	Walker A motif; other site
879088000706	ATP binding site [chemical binding]; other site
879088000707	Walker B motif; other site
879088000708	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
879088000709	DNA repair protein RadA; Provisional; Region: PRK11823
879088000710	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
879088000711	Walker A motif/ATP binding site; other site
879088000712	ATP binding site [chemical binding]; other site
879088000713	Walker B motif; other site
879088000714	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
879088000715	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
879088000716	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
879088000717	putative active site [active]
879088000718	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
879088000719	substrate binding site; other site
879088000720	dimer interface; other site
879088000721	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
879088000722	homotrimer interaction site [polypeptide binding]; other site
879088000723	zinc binding site [ion binding]; other site
879088000724	CDP-binding sites; other site
879088000725	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
879088000726	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
879088000727	HIGH motif; other site
879088000728	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
879088000729	active site
879088000730	KMSKS motif; other site
879088000731	serine O-acetyltransferase; Region: cysE; TIGR01172
879088000732	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
879088000733	trimer interface [polypeptide binding]; other site
879088000734	active site
879088000735	substrate binding site [chemical binding]; other site
879088000736	CoA binding site [chemical binding]; other site
879088000737	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
879088000738	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
879088000739	active site
879088000740	HIGH motif; other site
879088000741	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
879088000742	KMSKS motif; other site
879088000743	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
879088000744	tRNA binding surface [nucleotide binding]; other site
879088000745	anticodon binding site; other site
879088000746	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
879088000747	active site
879088000748	metal binding site [ion binding]; metal-binding site
879088000749	dimerization interface [polypeptide binding]; other site
879088000750	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
879088000751	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
879088000752	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
879088000753	Predicted RNA-binding protein containing a PIN domain [General function prediction only]; Region: COG3688
879088000754	RNA polymerase factor sigma-70; Validated; Region: PRK08295
879088000755	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
879088000756	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
879088000757	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
879088000758	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
879088000759	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
879088000760	putative homodimer interface [polypeptide binding]; other site
879088000761	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
879088000762	heterodimer interface [polypeptide binding]; other site
879088000763	homodimer interface [polypeptide binding]; other site
879088000764	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
879088000765	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
879088000766	23S rRNA interface [nucleotide binding]; other site
879088000767	L7/L12 interface [polypeptide binding]; other site
879088000768	putative thiostrepton binding site; other site
879088000769	L25 interface [polypeptide binding]; other site
879088000770	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
879088000771	mRNA/rRNA interface [nucleotide binding]; other site
879088000772	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
879088000773	23S rRNA interface [nucleotide binding]; other site
879088000774	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
879088000775	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
879088000776	core dimer interface [polypeptide binding]; other site
879088000777	peripheral dimer interface [polypeptide binding]; other site
879088000778	L10 interface [polypeptide binding]; other site
879088000779	L11 interface [polypeptide binding]; other site
879088000780	putative EF-Tu interaction site [polypeptide binding]; other site
879088000781	putative EF-G interaction site [polypeptide binding]; other site
879088000782	Methyltransferase domain; Region: Methyltransf_31; pfam13847
879088000783	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088000784	S-adenosylmethionine binding site [chemical binding]; other site
879088000785	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
879088000786	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088000787	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088000788	DNA binding site [nucleotide binding]
879088000789	domain linker motif; other site
879088000790	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
879088000791	putative dimerization interface [polypeptide binding]; other site
879088000792	putative ligand binding site [chemical binding]; other site
879088000793	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
879088000794	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088000795	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
879088000796	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000797	dimer interface [polypeptide binding]; other site
879088000798	conserved gate region; other site
879088000799	putative PBP binding loops; other site
879088000800	ABC-ATPase subunit interface; other site
879088000801	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088000802	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000803	dimer interface [polypeptide binding]; other site
879088000804	conserved gate region; other site
879088000805	putative PBP binding loops; other site
879088000806	ABC-ATPase subunit interface; other site
879088000807	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
879088000808	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
879088000809	Ca binding site [ion binding]; other site
879088000810	active site
879088000811	catalytic site [active]
879088000812	Alpha amylase catalytic domain found in sucrose phosphorylase (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase; cd11355
879088000813	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
879088000814	active site
879088000815	homodimer interface [polypeptide binding]; other site
879088000816	catalytic site [active]
879088000817	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
879088000818	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
879088000819	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
879088000820	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
879088000821	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
879088000822	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
879088000823	RPB10 interaction site [polypeptide binding]; other site
879088000824	RPB1 interaction site [polypeptide binding]; other site
879088000825	RPB11 interaction site [polypeptide binding]; other site
879088000826	RPB3 interaction site [polypeptide binding]; other site
879088000827	RPB12 interaction site [polypeptide binding]; other site
879088000828	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
879088000829	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
879088000830	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
879088000831	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
879088000832	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
879088000833	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
879088000834	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
879088000835	G-loop; other site
879088000836	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
879088000837	DNA binding site [nucleotide binding]
879088000838	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
879088000839	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
879088000840	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000841	active site
879088000842	motif I; other site
879088000843	motif II; other site
879088000844	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088000845	beta-galactosidase; Region: BGL; TIGR03356
879088000846	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
879088000847	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
879088000848	Walker A/P-loop; other site
879088000849	ATP binding site [chemical binding]; other site
879088000850	Q-loop/lid; other site
879088000851	ABC transporter signature motif; other site
879088000852	Walker B; other site
879088000853	D-loop; other site
879088000854	H-loop/switch region; other site
879088000855	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
879088000856	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
879088000857	Walker A/P-loop; other site
879088000858	ATP binding site [chemical binding]; other site
879088000859	Q-loop/lid; other site
879088000860	ABC transporter signature motif; other site
879088000861	Walker B; other site
879088000862	D-loop; other site
879088000863	H-loop/switch region; other site
879088000864	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088000865	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088000866	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088000867	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000868	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000869	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000870	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000871	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000872	LRR adjacent; Region: LRR_adjacent; pfam08191
879088000873	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088000874	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088000875	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088000876	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088000877	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000878	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000879	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000880	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000881	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000882	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000883	LRR adjacent; Region: LRR_adjacent; pfam08191
879088000884	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088000885	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088000886	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088000887	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000888	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000889	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088000890	Leucine-rich repeats; other site
879088000891	Substrate binding site [chemical binding]; other site
879088000892	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000893	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000894	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000895	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000896	LRR adjacent; Region: LRR_adjacent; pfam08191
879088000897	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088000898	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088000899	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
879088000900	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
879088000901	metal binding site [ion binding]; metal-binding site
879088000902	dimer interface [polypeptide binding]; other site
879088000903	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088000904	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088000905	putative Zn2+ binding site [ion binding]; other site
879088000906	putative DNA binding site [nucleotide binding]; other site
879088000907	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
879088000908	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088000909	Zn binding site [ion binding]; other site
879088000910	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
879088000911	Zn binding site [ion binding]; other site
879088000912	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088000913	catalytic core [active]
879088000914	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
879088000915	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
879088000916	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
879088000917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000918	dimer interface [polypeptide binding]; other site
879088000919	conserved gate region; other site
879088000920	ABC-ATPase subunit interface; other site
879088000921	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088000922	Substrate binding site [chemical binding]; other site
879088000923	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000924	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000925	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000926	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000927	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088000928	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
879088000929	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088000930	beta-galactosidase; Region: BGL; TIGR03356
879088000931	sugar phosphate phosphatase; Provisional; Region: PRK10513
879088000932	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000933	active site
879088000934	motif I; other site
879088000935	motif II; other site
879088000936	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000937	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088000938	Coenzyme A binding pocket [chemical binding]; other site
879088000939	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000940	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
879088000941	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
879088000942	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
879088000943	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000944	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
879088000945	active site
879088000946	motif I; other site
879088000947	motif II; other site
879088000948	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088000949	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088000950	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088000951	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
879088000952	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
879088000953	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
879088000954	Walker A/P-loop; other site
879088000955	ATP binding site [chemical binding]; other site
879088000956	Q-loop/lid; other site
879088000957	ABC transporter signature motif; other site
879088000958	Walker B; other site
879088000959	D-loop; other site
879088000960	H-loop/switch region; other site
879088000961	TOBE domain; Region: TOBE; pfam03459
879088000962	ATP cone domain; Region: ATP-cone; pfam03477
879088000963	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
879088000964	Class III ribonucleotide reductase; Region: RNR_III; cd01675
879088000965	effector binding site; other site
879088000966	active site
879088000967	Zn binding site [ion binding]; other site
879088000968	glycine loop; other site
879088000969	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
879088000970	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
879088000971	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088000972	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088000973	ligand binding site [chemical binding]; other site
879088000974	flexible hinge region; other site
879088000975	Predicted amidohydrolase [General function prediction only]; Region: COG0388
879088000976	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
879088000977	putative active site [active]
879088000978	catalytic triad [active]
879088000979	putative dimer interface [polypeptide binding]; other site
879088000980	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088000981	dimer interface [polypeptide binding]; other site
879088000982	conserved gate region; other site
879088000983	ABC-ATPase subunit interface; other site
879088000984	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
879088000985	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
879088000986	Walker A/P-loop; other site
879088000987	ATP binding site [chemical binding]; other site
879088000988	Q-loop/lid; other site
879088000989	ABC transporter signature motif; other site
879088000990	Walker B; other site
879088000991	D-loop; other site
879088000992	H-loop/switch region; other site
879088000993	NIL domain; Region: NIL; pfam09383
879088000994	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
879088000995	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
879088000996	transaminase; Reviewed; Region: PRK08068
879088000997	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088000998	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088000999	homodimer interface [polypeptide binding]; other site
879088001000	catalytic residue [active]
879088001001	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088001002	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088001003	active site
879088001004	phosphorylation site [posttranslational modification]
879088001005	intermolecular recognition site; other site
879088001006	dimerization interface [polypeptide binding]; other site
879088001007	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088001008	DNA binding site [nucleotide binding]
879088001009	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
879088001010	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088001011	dimerization interface [polypeptide binding]; other site
879088001012	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
879088001013	putative active site [active]
879088001014	heme pocket [chemical binding]; other site
879088001015	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088001016	dimer interface [polypeptide binding]; other site
879088001017	phosphorylation site [posttranslational modification]
879088001018	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088001019	ATP binding site [chemical binding]; other site
879088001020	Mg2+ binding site [ion binding]; other site
879088001021	G-X-G motif; other site
879088001022	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
879088001023	YycH protein; Region: YycH; pfam07435
879088001024	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4853
879088001025	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
879088001026	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
879088001027	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
879088001028	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
879088001029	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
879088001030	protein binding site [polypeptide binding]; other site
879088001031	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
879088001032	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088001033	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088001034	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
879088001035	dimerization interface [polypeptide binding]; other site
879088001036	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
879088001037	dimer interface [polypeptide binding]; other site
879088001038	FMN binding site [chemical binding]; other site
879088001039	NADPH bind site [chemical binding]; other site
879088001040	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088001041	HTH domain; Region: HTH_11; pfam08279
879088001042	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088001043	PRD domain; Region: PRD; pfam00874
879088001044	PRD domain; Region: PRD; pfam00874
879088001045	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088001046	active site
879088001047	P-loop; other site
879088001048	phosphorylation site [posttranslational modification]
879088001049	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001050	active site
879088001051	phosphorylation site [posttranslational modification]
879088001052	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088001053	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088001054	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088001055	active site
879088001056	P-loop; other site
879088001057	phosphorylation site [posttranslational modification]
879088001058	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088001059	beta-galactosidase; Region: BGL; TIGR03356
879088001060	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088001061	methionine cluster; other site
879088001062	active site
879088001063	phosphorylation site [posttranslational modification]
879088001064	metal binding site [ion binding]; metal-binding site
879088001065	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
879088001066	putative active site [active]
879088001067	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
879088001068	cofactor binding site; other site
879088001069	DNA binding site [nucleotide binding]
879088001070	substrate interaction site [chemical binding]; other site
879088001071	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
879088001072	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
879088001073	active site
879088001074	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
879088001075	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
879088001076	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088001077	catalytic residue [active]
879088001078	Peptidase family M48; Region: Peptidase_M48; cl12018
879088001079	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
879088001080	uncharacterized YdjC-like family proteins from bacteria; Region: YdjC_like_1; cd10805
879088001081	putative active site [active]
879088001082	YdjC motif; other site
879088001083	Mg binding site [ion binding]; other site
879088001084	putative homodimer interface [polypeptide binding]; other site
879088001085	Putative transcription activator [Transcription]; Region: TenA; COG0819
879088001086	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
879088001087	substrate binding site [chemical binding]; other site
879088001088	multimerization interface [polypeptide binding]; other site
879088001089	ATP binding site [chemical binding]; other site
879088001090	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
879088001091	dimer interface [polypeptide binding]; other site
879088001092	substrate binding site [chemical binding]; other site
879088001093	ATP binding site [chemical binding]; other site
879088001094	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
879088001095	thiamine phosphate binding site [chemical binding]; other site
879088001096	active site
879088001097	pyrophosphate binding site [ion binding]; other site
879088001098	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088001099	beta-galactosidase; Region: BGL; TIGR03356
879088001100	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001101	Protein of unknown function (DUF2910); Region: DUF2910; pfam11139
879088001102	Protein of unknown function (DUF1696); Region: DUF1696; pfam08000
879088001103	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
879088001104	putative catalytic site [active]
879088001105	putative metal binding site [ion binding]; other site
879088001106	putative phosphate binding site [ion binding]; other site
879088001107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088001108	non-specific DNA binding site [nucleotide binding]; other site
879088001109	salt bridge; other site
879088001110	sequence-specific DNA binding site [nucleotide binding]; other site
879088001111	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
879088001112	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088001113	non-specific DNA binding site [nucleotide binding]; other site
879088001114	salt bridge; other site
879088001115	sequence-specific DNA binding site [nucleotide binding]; other site
879088001116	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
879088001117	Leucine rich repeat; Region: LRR_8; pfam13855
879088001118	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001119	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001120	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001121	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001122	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001123	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001124	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001125	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001126	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001127	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001128	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001129	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001130	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001131	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001132	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001133	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001134	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001135	Leucine rich repeat; Region: LRR_8; pfam13855
879088001136	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001137	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001138	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088001139	Leucine-rich repeats; other site
879088001140	Substrate binding site [chemical binding]; other site
879088001141	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001142	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001143	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001144	Leucine rich repeat; Region: LRR_8; pfam13855
879088001145	Leucine rich repeat; Region: LRR_8; pfam13855
879088001146	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088001147	Leucine-rich repeats; other site
879088001148	Substrate binding site [chemical binding]; other site
879088001149	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001150	Leucine rich repeat; Region: LRR_8; pfam13855
879088001151	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001152	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001153	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001154	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001155	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001156	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001157	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001158	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
879088001159	Protein of unknown function (DUF3130; Region: DUF3130; pfam11328
879088001160	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088001161	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
879088001162	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
879088001163	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
879088001164	TPP-binding site [chemical binding]; other site
879088001165	dimer interface [polypeptide binding]; other site
879088001166	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
879088001167	PYR/PP interface [polypeptide binding]; other site
879088001168	dimer interface [polypeptide binding]; other site
879088001169	TPP binding site [chemical binding]; other site
879088001170	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088001171	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
879088001172	active site
879088001173	intersubunit interactions; other site
879088001174	catalytic residue [active]
879088001175	short chain dehydrogenase; Provisional; Region: PRK06841
879088001176	classical (c) SDRs; Region: SDR_c; cd05233
879088001177	NAD(P) binding site [chemical binding]; other site
879088001178	active site
879088001179	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
879088001180	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
879088001181	substrate binding site [chemical binding]; other site
879088001182	dimer interface [polypeptide binding]; other site
879088001183	catalytic triad [active]
879088001184	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
879088001185	DAK2 domain; Region: Dak2; cl03685
879088001186	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
879088001187	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
879088001188	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
879088001189	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088001190	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088001191	putative DNA binding site [nucleotide binding]; other site
879088001192	putative Zn2+ binding site [ion binding]; other site
879088001193	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088001194	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088001195	Coenzyme A binding pocket [chemical binding]; other site
879088001196	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088001197	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088001198	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001199	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001200	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001201	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
879088001202	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
879088001203	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
879088001204	acyl-activating enzyme (AAE) consensus motif; other site
879088001205	acyl-activating enzyme (AAE) consensus motif; other site
879088001206	AMP binding site [chemical binding]; other site
879088001207	active site
879088001208	CoA binding site [chemical binding]; other site
879088001209	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
879088001210	L-aspartate oxidase; Provisional; Region: PRK06175
879088001211	putative oxidoreductase; Provisional; Region: PRK10206
879088001212	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088001213	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
879088001214	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001215	active site
879088001216	phosphorylation site [posttranslational modification]
879088001217	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
879088001218	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088001219	active site
879088001220	P-loop; other site
879088001221	phosphorylation site [posttranslational modification]
879088001222	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088001223	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
879088001224	intersubunit interface [polypeptide binding]; other site
879088001225	active site
879088001226	zinc binding site [ion binding]; other site
879088001227	Na+ binding site [ion binding]; other site
879088001228	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088001229	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
879088001230	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088001231	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
879088001232	conserved cys residue [active]
879088001233	Predicted transcriptional regulator [Transcription]; Region: COG2378
879088001234	HTH domain; Region: HTH_11; pfam08279
879088001235	WYL domain; Region: WYL; pfam13280
879088001236	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
879088001237	nudix motif; other site
879088001238	hypothetical protein; Provisional; Region: PRK12378
879088001239	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
879088001240	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
879088001241	PhnA protein; Region: PhnA; pfam03831
879088001242	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088001243	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088001244	DNA-binding site [nucleotide binding]; DNA binding site
879088001245	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
879088001246	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088001247	beta-galactosidase; Region: BGL; TIGR03356
879088001248	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088001249	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
879088001250	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088001251	active site
879088001252	P-loop; other site
879088001253	phosphorylation site [posttranslational modification]
879088001254	WYL domain; Region: WYL; pfam13280
879088001255	Predicted transcriptional regulator [Transcription]; Region: COG2378
879088001256	HTH domain; Region: HTH_11; pfam08279
879088001257	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
879088001258	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088001259	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
879088001260	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088001261	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
879088001262	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
879088001263	tetrameric interface [polypeptide binding]; other site
879088001264	NAD binding site [chemical binding]; other site
879088001265	catalytic residues [active]
879088001266	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
879088001267	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
879088001268	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
879088001269	substrate binding site [chemical binding]; other site
879088001270	ATP binding site [chemical binding]; other site
879088001271	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
879088001272	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
879088001273	PYR/PP interface [polypeptide binding]; other site
879088001274	dimer interface [polypeptide binding]; other site
879088001275	TPP binding site [chemical binding]; other site
879088001276	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
879088001277	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
879088001278	TPP-binding site; other site
879088001279	Uncharacterized conserved protein [Function unknown]; Region: COG5646
879088001280	Bacterial low temperature requirement A protein (LtrA); Region: LtrA; cl01754
879088001281	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
879088001282	ligand binding site [chemical binding]; other site
879088001283	active site
879088001284	UGI interface [polypeptide binding]; other site
879088001285	catalytic site [active]
879088001286	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
879088001287	hypothetical protein; Provisional; Region: PRK13665
879088001288	Bacterial SH3 domain; Region: SH3_3; cl17532
879088001289	NlpC/P60 family; Region: NLPC_P60; pfam00877
879088001290	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088001291	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088001292	Coenzyme A binding pocket [chemical binding]; other site
879088001293	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
879088001294	pyrroline-5-carboxylate reductase; Region: PLN02688
879088001295	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088001296	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001297	Transcriptional regulators [Transcription]; Region: GntR; COG1802
879088001298	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088001299	DNA-binding site [nucleotide binding]; DNA binding site
879088001300	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
879088001301	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088001302	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088001303	Walker A/P-loop; other site
879088001304	ATP binding site [chemical binding]; other site
879088001305	Q-loop/lid; other site
879088001306	ABC transporter signature motif; other site
879088001307	Walker B; other site
879088001308	D-loop; other site
879088001309	H-loop/switch region; other site
879088001310	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088001311	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088001312	FtsX-like permease family; Region: FtsX; pfam02687
879088001313	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_6; cd08899
879088001314	putative hydrophobic ligand binding site [chemical binding]; other site
879088001315	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001316	active site
879088001317	phosphorylation site [posttranslational modification]
879088001318	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088001319	active site
879088001320	P-loop; other site
879088001321	phosphorylation site [posttranslational modification]
879088001322	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088001323	alpha-mannosidase; Provisional; Region: PRK09819
879088001324	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
879088001325	active site
879088001326	metal binding site [ion binding]; metal-binding site
879088001327	catalytic site [active]
879088001328	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
879088001329	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088001330	HTH domain; Region: HTH_11; pfam08279
879088001331	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088001332	PRD domain; Region: PRD; pfam00874
879088001333	PRD domain; Region: PRD; pfam00874
879088001334	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088001335	active site
879088001336	P-loop; other site
879088001337	phosphorylation site [posttranslational modification]
879088001338	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001339	active site
879088001340	phosphorylation site [posttranslational modification]
879088001341	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
879088001342	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
879088001343	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088001344	putative metal binding site [ion binding]; other site
879088001345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4835
879088001346	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
879088001347	trimer interface [polypeptide binding]; other site
879088001348	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088001349	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001350	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088001351	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001352	Leucine-rich repeats; other site
879088001353	Substrate binding site [chemical binding]; other site
879088001354	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001355	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001356	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001357	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001358	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001359	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001360	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001361	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001362	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001363	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001364	phosphoenolpyruvate synthase; Validated; Region: PRK06241
879088001365	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
879088001366	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
879088001367	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
879088001368	ZIP Zinc transporter; Region: Zip; pfam02535
879088001369	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
879088001370	Catalytic NodB homology domain of Clostridium thermocellum acetylxylan esterase and its bacterial homologs; Region: CE4_CtAXE_like; cd10954
879088001371	NodB motif; other site
879088001372	active site
879088001373	catalytic site [active]
879088001374	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088001375	non-specific DNA binding site [nucleotide binding]; other site
879088001376	salt bridge; other site
879088001377	sequence-specific DNA binding site [nucleotide binding]; other site
879088001378	Protein of unknown function (DUF1211); Region: DUF1211; pfam06736
879088001379	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088001380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088001381	active site
879088001382	motif I; other site
879088001383	motif II; other site
879088001384	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088001385	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
879088001386	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088001387	HTH domain; Region: HTH_11; pfam08279
879088001388	PRD domain; Region: PRD; pfam00874
879088001389	PRD domain; Region: PRD; pfam00874
879088001390	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088001391	active site
879088001392	P-loop; other site
879088001393	phosphorylation site [posttranslational modification]
879088001394	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001395	active site
879088001396	phosphorylation site [posttranslational modification]
879088001397	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001398	active site
879088001399	phosphorylation site [posttranslational modification]
879088001400	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088001401	active site
879088001402	P-loop; other site
879088001403	phosphorylation site [posttranslational modification]
879088001404	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088001405	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
879088001406	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
879088001407	active site
879088001408	metal binding site [ion binding]; metal-binding site
879088001409	catalytic site [active]
879088001410	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
879088001411	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088001412	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088001413	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
879088001414	dimerization interface [polypeptide binding]; other site
879088001415	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
879088001416	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
879088001417	active site
879088001418	substrate binding site [chemical binding]; other site
879088001419	trimer interface [polypeptide binding]; other site
879088001420	CoA binding site [chemical binding]; other site
879088001421	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
879088001422	classical (c) SDRs; Region: SDR_c; cd05233
879088001423	NAD(P) binding site [chemical binding]; other site
879088001424	active site
879088001425	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
879088001426	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
879088001427	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
879088001428	RHS Repeat; Region: RHS_repeat; pfam05593
879088001429	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
879088001430	RHS Repeat; Region: RHS_repeat; pfam05593
879088001431	RHS Repeat; Region: RHS_repeat; pfam05593
879088001432	RHS Repeat; Region: RHS_repeat; pfam05593
879088001433	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
879088001434	HEAT repeats; Region: HEAT_2; pfam13646
879088001435	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088001436	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088001437	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088001438	Substrate binding site [chemical binding]; other site
879088001439	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001440	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001441	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001442	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001443	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
879088001444	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088001445	Leucine rich repeat; Region: LRR_8; pfam13855
879088001446	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088001447	Leucine rich repeat; Region: LRR_8; pfam13855
879088001448	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001449	LRR adjacent; Region: LRR_adjacent; pfam08191
879088001450	Listeria/Bacterioides repeat; Region: List_Bact_rpt; TIGR02543
879088001451	SH3-like domain; Region: SH3_8; pfam13457
879088001452	Predicted transcriptional regulator [Transcription]; Region: COG1959
879088001453	Transcriptional regulator; Region: Rrf2; pfam02082
879088001454	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
879088001455	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
879088001456	NAD(P) binding site [chemical binding]; other site
879088001457	active site
879088001458	Uncharacterized protein containing a NRPS condensation (elongation) domain [General function prediction only]; Region: COG4908
879088001459	Protein of unknown function (DUF2004); Region: DUF2004; pfam09406
879088001460	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
879088001461	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
879088001462	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
879088001463	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
879088001464	Transcriptional regulator [Transcription]; Region: LytR; COG1316
879088001465	Protein of unknown function (DUF4240); Region: DUF4240; pfam14024
879088001466	Signal peptide peptidase; Region: Peptidase_A22B; cl01342
879088001467	Predicted membrane protein [Function unknown]; Region: COG3619
879088001468	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
879088001469	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
879088001470	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
879088001471	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
879088001472	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
879088001473	Protein of unknown function DUF58; Region: DUF58; pfam01882
879088001474	MoxR-like ATPases [General function prediction only]; Region: COG0714
879088001475	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088001476	Walker A motif; other site
879088001477	ATP binding site [chemical binding]; other site
879088001478	Walker B motif; other site
879088001479	arginine finger; other site
879088001480	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
879088001481	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
879088001482	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
879088001483	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
879088001484	Na binding site [ion binding]; other site
879088001485	Uncharacterized conserved protein [Function unknown]; Region: COG3535
879088001486	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
879088001487	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088001488	nucleotide binding site [chemical binding]; other site
879088001489	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
879088001490	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088001491	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088001492	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001493	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001494	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001495	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001496	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001497	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088001498	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001499	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001500	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001501	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001502	Leucine rich repeat; Region: LRR_8; pfam13855
879088001503	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001504	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088001505	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001506	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001507	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001508	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088001509	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001510	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001511	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001512	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001513	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088001514	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088001515	Transposase; Region: HTH_Tnp_1; cl17663
879088001516	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088001517	Zn2+ binding site [ion binding]; other site
879088001518	Mg2+ binding site [ion binding]; other site
879088001519	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
879088001520	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
879088001521	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088001522	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
879088001523	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
879088001524	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
879088001525	FeS/SAM binding site; other site
879088001526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
879088001527	heme-degrading monooxygenase IsdG; Provisional; Region: PRK13316
879088001528	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088001529	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
879088001530	putative FMN binding site [chemical binding]; other site
879088001531	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
879088001532	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
879088001533	nudix motif; other site
879088001534	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088001535	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088001536	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
879088001537	putative dimerization interface [polypeptide binding]; other site
879088001538	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
879088001539	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
879088001540	active site
879088001541	FMN binding site [chemical binding]; other site
879088001542	substrate binding site [chemical binding]; other site
879088001543	putative catalytic residue [active]
879088001544	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
879088001545	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088001546	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088001547	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
879088001548	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
879088001549	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
879088001550	shikimate binding site; other site
879088001551	NAD(P) binding site [chemical binding]; other site
879088001552	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
879088001553	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
879088001554	active site
879088001555	catalytic residue [active]
879088001556	dimer interface [polypeptide binding]; other site
879088001557	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088001558	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088001559	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
879088001560	dimerization interface [polypeptide binding]; other site
879088001561	substrate binding pocket [chemical binding]; other site
879088001562	Predicted acyl esterases [General function prediction only]; Region: COG2936
879088001563	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
879088001564	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
879088001565	active site
879088001566	catalytic triad [active]
879088001567	oxyanion hole [active]
879088001568	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
879088001569	EamA-like transporter family; Region: EamA; pfam00892
879088001570	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4224
879088001571	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
879088001572	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
879088001573	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
879088001574	substrate binding site [chemical binding]; other site
879088001575	hexamer interface [polypeptide binding]; other site
879088001576	metal binding site [ion binding]; metal-binding site
879088001577	Transaldolase [Carbohydrate transport and metabolism]; Region: MipB; COG0176
879088001578	catalytic residue [active]
879088001579	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088001580	PRD domain; Region: PRD; pfam00874
879088001581	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088001582	active site
879088001583	P-loop; other site
879088001584	phosphorylation site [posttranslational modification]
879088001585	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001586	active site
879088001587	phosphorylation site [posttranslational modification]
879088001588	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
879088001589	putative active site [active]
879088001590	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001591	active site
879088001592	phosphorylation site [posttranslational modification]
879088001593	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
879088001594	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
879088001595	substrate binding site [chemical binding]; other site
879088001596	hexamer interface [polypeptide binding]; other site
879088001597	metal binding site [ion binding]; metal-binding site
879088001598	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
879088001599	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
879088001600	putative NAD(P) binding site [chemical binding]; other site
879088001601	catalytic Zn binding site [ion binding]; other site
879088001602	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
879088001603	active site
879088001604	P-loop; other site
879088001605	phosphorylation site [posttranslational modification]
879088001606	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
879088001607	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
879088001608	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
879088001609	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
879088001610	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088001611	active site
879088001612	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
879088001613	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
879088001614	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
879088001615	catalytic triad [active]
879088001616	conserved hypothetical protein; Region: lin0512_fam; TIGR02058
879088001617	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088001618	MarR family; Region: MarR_2; pfam12802
879088001619	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001620	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001621	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
879088001622	Ligand Binding Site [chemical binding]; other site
879088001623	Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]; Region: PgsA; COG2843
879088001624	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
879088001625	putative active site [active]
879088001626	putative metal binding site [ion binding]; other site
879088001627	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001628	catalytic core [active]
879088001629	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001630	Predicted membrane protein [Function unknown]; Region: COG3759
879088001631	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088001632	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088001633	putative substrate translocation pore; other site
879088001634	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
879088001635	non-specific DNA interactions [nucleotide binding]; other site
879088001636	DNA binding site [nucleotide binding]
879088001637	sequence specific DNA binding site [nucleotide binding]; other site
879088001638	putative cAMP binding site [chemical binding]; other site
879088001639	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088001640	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
879088001641	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
879088001642	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
879088001643	NAD binding site [chemical binding]; other site
879088001644	sugar binding site [chemical binding]; other site
879088001645	divalent metal binding site [ion binding]; other site
879088001646	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088001647	dimer interface [polypeptide binding]; other site
879088001648	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088001649	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088001650	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088001651	putative active site [active]
879088001652	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
879088001653	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
879088001654	Sulfate transporter family; Region: Sulfate_transp; pfam00916
879088001655	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
879088001656	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
879088001657	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
879088001658	DNA binding residues [nucleotide binding]
879088001659	dimer interface [polypeptide binding]; other site
879088001660	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
879088001661	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
879088001662	Uncharacterized protein conserved in bacteria (DUF2334); Region: DUF2334; pfam10096
879088001663	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
879088001664	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
879088001665	DXD motif; other site
879088001666	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
879088001667	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
879088001668	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
879088001669	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088001670	S-adenosylmethionine binding site [chemical binding]; other site
879088001671	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
879088001672	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
879088001673	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088001674	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088001675	DNA binding site [nucleotide binding]
879088001676	domain linker motif; other site
879088001677	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
879088001678	putative dimerization interface [polypeptide binding]; other site
879088001679	putative ligand binding site [chemical binding]; other site
879088001680	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
879088001681	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
879088001682	NAD binding site [chemical binding]; other site
879088001683	sugar binding site [chemical binding]; other site
879088001684	divalent metal binding site [ion binding]; other site
879088001685	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088001686	dimer interface [polypeptide binding]; other site
879088001687	allantoate amidohydrolase; Reviewed; Region: PRK09290
879088001688	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
879088001689	active site
879088001690	metal binding site [ion binding]; metal-binding site
879088001691	dimer interface [polypeptide binding]; other site
879088001692	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
879088001693	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
879088001694	metal binding site [ion binding]; metal-binding site
879088001695	putative dimer interface [polypeptide binding]; other site
879088001696	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
879088001697	Beta-lactamase; Region: Beta-lactamase; pfam00144
879088001698	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
879088001699	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
879088001700	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
879088001701	intersubunit interface [polypeptide binding]; other site
879088001702	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
879088001703	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
879088001704	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
879088001705	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
879088001706	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
879088001707	Glucitol operon activator protein (GutM); Region: GutM; cl01890
879088001708	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
879088001709	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088001710	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
879088001711	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
879088001712	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
879088001713	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088001714	Antagonist of mitotic exit network protein 1; Region: AMN1; cl15308
879088001715	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001716	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001717	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001718	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088001719	WxL domain surface cell wall-binding; Region: WxL; pfam13731
879088001720	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
879088001721	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
879088001722	FOG: CBS domain [General function prediction only]; Region: COG0517
879088001723	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
879088001724	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
879088001725	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
879088001726	dimer interface [polypeptide binding]; other site
879088001727	active site
879088001728	metal binding site [ion binding]; metal-binding site
879088001729	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
879088001730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088001731	putative substrate translocation pore; other site
879088001732	POT family; Region: PTR2; pfam00854
879088001733	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001734	catalytic core [active]
879088001735	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001736	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001737	catalytic core [active]
879088001738	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088001739	3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706
879088001740	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
879088001741	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
879088001742	Cl binding site [ion binding]; other site
879088001743	oligomer interface [polypeptide binding]; other site
879088001744	glutamate dehydrogenase; Provisional; Region: PRK09414
879088001745	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
879088001746	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
879088001747	NAD(P) binding site [chemical binding]; other site
879088001748	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
879088001749	metal binding site [ion binding]; metal-binding site
879088001750	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
879088001751	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
879088001752	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
879088001753	substrate binding site [chemical binding]; other site
879088001754	glutamase interaction surface [polypeptide binding]; other site
879088001755	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
879088001756	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
879088001757	catalytic residues [active]
879088001758	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
879088001759	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
879088001760	putative active site [active]
879088001761	oxyanion strand; other site
879088001762	catalytic triad [active]
879088001763	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
879088001764	putative active site pocket [active]
879088001765	4-fold oligomerization interface [polypeptide binding]; other site
879088001766	metal binding residues [ion binding]; metal-binding site
879088001767	3-fold/trimer interface [polypeptide binding]; other site
879088001768	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
879088001769	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
879088001770	NAD binding site [chemical binding]; other site
879088001771	dimerization interface [polypeptide binding]; other site
879088001772	product binding site; other site
879088001773	substrate binding site [chemical binding]; other site
879088001774	zinc binding site [ion binding]; other site
879088001775	catalytic residues [active]
879088001776	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
879088001777	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
879088001778	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
879088001779	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
879088001780	dimer interface [polypeptide binding]; other site
879088001781	motif 1; other site
879088001782	active site
879088001783	motif 2; other site
879088001784	motif 3; other site
879088001785	histidinol-phosphatase; Reviewed; Region: PRK08123
879088001786	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
879088001787	active site
879088001788	dimer interface [polypeptide binding]; other site
879088001789	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
879088001790	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
879088001791	DNA binding site [nucleotide binding]
879088001792	active site
879088001793	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
879088001794	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
879088001795	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088001796	beta-galactosidase; Region: BGL; TIGR03356
879088001797	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088001798	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088001799	DNA-binding site [nucleotide binding]; DNA binding site
879088001800	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
879088001801	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001802	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088001803	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
879088001804	Uncharacterized conserved protein [Function unknown]; Region: COG2966
879088001805	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
879088001806	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
879088001807	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
879088001808	Predicted esterase [General function prediction only]; Region: COG0400
879088001809	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
879088001810	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
879088001811	putative RNA binding site [nucleotide binding]; other site
879088001812	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088001813	S-adenosylmethionine binding site [chemical binding]; other site
879088001814	invasion associated secreted endopeptidase; Provisional; Region: PRK13914
879088001815	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088001816	Bacterial SH3 domain; Region: SH3_3; pfam08239
879088001817	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088001818	NlpC/P60 family; Region: NLPC_P60; pfam00877
879088001819	preprotein translocase subunit SecA; Reviewed; Region: PRK09200
879088001820	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
879088001821	ATP binding site [chemical binding]; other site
879088001822	putative Mg++ binding site [ion binding]; other site
879088001823	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
879088001824	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
879088001825	nucleotide binding region [chemical binding]; other site
879088001826	ATP-binding site [chemical binding]; other site
879088001827	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
879088001828	Domain of unknown function DUF20; Region: UPF0118; pfam01594
879088001829	WxL domain surface cell wall-binding; Region: WxL; pfam13731
879088001830	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
879088001831	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
879088001832	UreD urease accessory protein; Region: UreD; cl00530
879088001833	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
879088001834	DNA photolyase; Region: DNA_photolyase; pfam00875
879088001835	Predicted membrane protein [Function unknown]; Region: COG4852
879088001836	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
879088001837	DAK2 domain; Region: Dak2; pfam02734
879088001838	EDD domain protein, DegV family; Region: DegV; TIGR00762
879088001839	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
879088001840	Steroid 5-alpha reductase family enzyme [General function prediction only]; Region: COG3752
879088001841	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
879088001842	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
879088001843	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
879088001844	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
879088001845	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
879088001846	homodimer interface [polypeptide binding]; other site
879088001847	substrate-cofactor binding pocket; other site
879088001848	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088001849	catalytic residue [active]
879088001850	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
879088001851	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088001852	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
879088001853	ligand binding site [chemical binding]; other site
879088001854	flexible hinge region; other site
879088001855	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088001856	BioY family; Region: BioY; pfam02632
879088001857	Predicted transcriptional regulators [Transcription]; Region: COG1695
879088001858	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
879088001859	Predicted membrane protein [Function unknown]; Region: COG4709
879088001860	Uncharacterized conserved protein [Function unknown]; Region: COG3595
879088001861	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
879088001862	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
879088001863	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
879088001864	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
879088001865	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088001866	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
879088001867	Coenzyme A binding pocket [chemical binding]; other site
879088001868	Tic20-like protein; Region: Tic20; pfam09685
879088001869	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
879088001870	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
879088001871	Transcriptional regulators [Transcription]; Region: MarR; COG1846
879088001872	MarR family; Region: MarR_2; pfam12802
879088001873	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088001874	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088001875	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088001876	Walker A/P-loop; other site
879088001877	ATP binding site [chemical binding]; other site
879088001878	Q-loop/lid; other site
879088001879	ABC transporter signature motif; other site
879088001880	Walker B; other site
879088001881	D-loop; other site
879088001882	H-loop/switch region; other site
879088001883	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088001884	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088001885	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
879088001886	Walker A/P-loop; other site
879088001887	ATP binding site [chemical binding]; other site
879088001888	Q-loop/lid; other site
879088001889	ABC transporter signature motif; other site
879088001890	Walker B; other site
879088001891	D-loop; other site
879088001892	H-loop/switch region; other site
879088001893	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
879088001894	active site residue [active]
879088001895	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088001896	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
879088001897	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
879088001898	Transcriptional regulators [Transcription]; Region: MarR; COG1846
879088001899	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088001900	putative DNA binding site [nucleotide binding]; other site
879088001901	putative Zn2+ binding site [ion binding]; other site
879088001902	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
879088001903	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
879088001904	putative NAD(P) binding site [chemical binding]; other site
879088001905	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
879088001906	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
879088001907	Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: COG4781
879088001908	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
879088001909	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
879088001910	putative active site [active]
879088001911	catalytic site [active]
879088001912	putative metal binding site [ion binding]; other site
879088001913	Catalytic domain of Protein Kinases; Region: PKc; cd00180
879088001914	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
879088001915	active site
879088001916	ATP binding site [chemical binding]; other site
879088001917	substrate binding site [chemical binding]; other site
879088001918	activation loop (A-loop); other site
879088001919	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
879088001920	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
879088001921	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
879088001922	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
879088001923	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088001924	Coenzyme A binding pocket [chemical binding]; other site
879088001925	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
879088001926	active site
879088001927	catalytic triad [active]
879088001928	oxyanion hole [active]
879088001929	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
879088001930	domain interaction interfaces [polypeptide binding]; other site
879088001931	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
879088001932	domain interaction interfaces [polypeptide binding]; other site
879088001933	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
879088001934	domain interaction interfaces [polypeptide binding]; other site
879088001935	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
879088001936	domain interaction interfaces [polypeptide binding]; other site
879088001937	Isochorismatase family; Region: Isochorismatase; pfam00857
879088001938	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
879088001939	catalytic triad [active]
879088001940	conserved cis-peptide bond; other site
879088001941	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088001942	PRD domain; Region: PRD; pfam00874
879088001943	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088001944	active site
879088001945	P-loop; other site
879088001946	phosphorylation site [posttranslational modification]
879088001947	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001948	active site
879088001949	phosphorylation site [posttranslational modification]
879088001950	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088001951	active site
879088001952	phosphorylation site [posttranslational modification]
879088001953	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
879088001954	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088001955	active site
879088001956	P-loop; other site
879088001957	phosphorylation site [posttranslational modification]
879088001958	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211
879088001959	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
879088001960	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088001961	motif II; other site
879088001962	Predicted transcriptional regulator [Transcription]; Region: COG1959
879088001963	Transcriptional regulator; Region: Rrf2; pfam02082
879088001964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088001965	S-adenosylmethionine binding site [chemical binding]; other site
879088001966	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
879088001967	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
879088001968	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088001969	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088001970	active site
879088001971	catalytic tetrad [active]
879088001972	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
879088001973	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088001974	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088001975	motif II; other site
879088001976	Transaldolase [Carbohydrate transport and metabolism]; Region: MipB; COG0176
879088001977	catalytic residue [active]
879088001978	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
879088001979	Sulfatase; Region: Sulfatase; pfam00884
879088001980	amino acid transporter; Region: 2A0306; TIGR00909
879088001981	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
879088001982	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
879088001983	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
879088001984	putative metal binding site [ion binding]; other site
879088001985	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
879088001986	active site
879088001987	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
879088001988	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
879088001989	Cl binding site [ion binding]; other site
879088001990	oligomer interface [polypeptide binding]; other site
879088001991	Transcriptional regulators [Transcription]; Region: GntR; COG1802
879088001992	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088001993	DNA-binding site [nucleotide binding]; DNA binding site
879088001994	Predicted membrane protein [Function unknown]; Region: COG1511
879088001995	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
879088001996	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088001997	Transcriptional regulators [Transcription]; Region: GntR; COG1802
879088001998	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088001999	DNA-binding site [nucleotide binding]; DNA binding site
879088002000	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
879088002001	Predicted integral membrane protein [Function unknown]; Region: COG5523
879088002002	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
879088002003	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
879088002004	active site
879088002005	metal binding site [ion binding]; metal-binding site
879088002006	AAA domain; Region: AAA_13; pfam13166
879088002007	Predicted membrane protein [Function unknown]; Region: COG2322
879088002008	Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair]; Region: COG2231
879088002009	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
879088002010	minor groove reading motif; other site
879088002011	helix-hairpin-helix signature motif; other site
879088002012	substrate binding pocket [chemical binding]; other site
879088002013	active site
879088002014	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088002015	non-specific DNA binding site [nucleotide binding]; other site
879088002016	salt bridge; other site
879088002017	sequence-specific DNA binding site [nucleotide binding]; other site
879088002018	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
879088002019	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
879088002020	Transposase; Region: HTH_Tnp_1; cl17663
879088002021	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088002022	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002023	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002024	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
879088002025	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
879088002026	dimer interface [polypeptide binding]; other site
879088002027	substrate binding site [chemical binding]; other site
879088002028	ATP binding site [chemical binding]; other site
879088002029	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088002030	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088002031	active site
879088002032	motif I; other site
879088002033	motif II; other site
879088002034	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088002035	maltose O-acetyltransferase; Provisional; Region: PRK10092
879088002036	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
879088002037	active site
879088002038	substrate binding site [chemical binding]; other site
879088002039	trimer interface [polypeptide binding]; other site
879088002040	CoA binding site [chemical binding]; other site
879088002041	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
879088002042	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088002043	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
879088002044	Walker A/P-loop; other site
879088002045	ATP binding site [chemical binding]; other site
879088002046	Q-loop/lid; other site
879088002047	ABC transporter signature motif; other site
879088002048	Walker B; other site
879088002049	D-loop; other site
879088002050	H-loop/switch region; other site
879088002051	inner membrane transport permease; Provisional; Region: PRK15066
879088002052	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
879088002053	oxidoreductase; Provisional; Region: PRK07985
879088002054	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
879088002055	NAD(P) binding site [chemical binding]; other site
879088002056	active site
879088002057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
879088002058	Predicted membrane protein [Function unknown]; Region: COG3152
879088002059	DNA binding domain of the motility gene repressor (MogR); Region: MogR_DNAbind; pfam12181
879088002060	Flagellar biosynthesis pathway, component FliP [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliP; COG1338
879088002061	Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987
879088002062	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
879088002063	Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; COG1377
879088002064	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
879088002065	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
879088002066	FHIPEP family; Region: FHIPEP; pfam00771
879088002067	flagellar biosynthesis regulator FlhF; Provisional; Region: PRK12726
879088002068	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
879088002069	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12819
879088002070	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
879088002071	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
879088002072	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
879088002073	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
879088002074	Protein of unknown function (DUF3964); Region: DUF3964; pfam13107
879088002075	flagellar motor protein MotA; Validated; Region: PRK08124
879088002076	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
879088002077	flagellar motor protein MotB; Reviewed; Region: motB; PRK07734
879088002078	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
879088002079	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
879088002080	ligand binding site [chemical binding]; other site
879088002081	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
879088002082	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
879088002083	putative metal binding site; other site
879088002084	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088002085	binding surface
879088002086	TPR motif; other site
879088002087	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
879088002088	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
879088002089	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088002090	active site
879088002091	phosphorylation site [posttranslational modification]
879088002092	intermolecular recognition site; other site
879088002093	dimerization interface [polypeptide binding]; other site
879088002094	flagellin; Provisional; Region: PRK12805
879088002095	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
879088002096	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
879088002097	Response regulator receiver domain; Region: Response_reg; pfam00072
879088002098	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088002099	active site
879088002100	phosphorylation site [posttranslational modification]
879088002101	intermolecular recognition site; other site
879088002102	dimerization interface [polypeptide binding]; other site
879088002103	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
879088002104	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
879088002105	putative binding surface; other site
879088002106	active site
879088002107	P2 response regulator binding domain; Region: P2; pfam07194
879088002108	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
879088002109	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088002110	ATP binding site [chemical binding]; other site
879088002111	Mg2+ binding site [ion binding]; other site
879088002112	G-X-G motif; other site
879088002113	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
879088002114	flagellar motor switch protein; Validated; Region: PRK06788
879088002115	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
879088002116	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK11911
879088002117	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
879088002118	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
879088002119	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
879088002120	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
879088002121	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
879088002122	flagellar motor switch protein; Validated; Region: PRK06789
879088002123	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
879088002124	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
879088002125	flagellar motor switch protein; Reviewed; Region: PRK06782
879088002126	CheC-like family; Region: CheC; pfam04509
879088002127	CheC-like family; Region: CheC; pfam04509
879088002128	Chemotaxis phosphatase CheX; Region: CheX; cl15816
879088002129	CheC-like family; Region: CheC; pfam04509
879088002130	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
879088002131	Protein of unknown function (DUF327); Region: DUF327; pfam03885
879088002132	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06799
879088002133	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
879088002134	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08073
879088002135	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
879088002136	flagellar capping protein; Validated; Region: fliD; PRK06798
879088002137	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
879088002138	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
879088002139	Flagellin-specific chaperone FliS [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliS; COG1516
879088002140	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK06797
879088002141	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgC; COG1558
879088002142	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
879088002143	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK01699
879088002144	Flagellar basal body M-ring protein [Cell motility and secretion]; Region: fliF; COG1766
879088002145	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
879088002146	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
879088002147	Flagellar motor switch protein [Cell motility and secretion]; Region: FliG; COG1536
879088002148	FliG C-terminal domain; Region: FliG_C; pfam01706
879088002149	flagellar assembly protein H; Validated; Region: fliH; PRK06800
879088002150	Flagellar assembly protein FliH; Region: FliH; pfam02108
879088002151	flagellum-specific ATP synthase; Validated; Region: fliI; PRK06793
879088002152	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
879088002153	Walker A motif; other site
879088002154	ATP binding site [chemical binding]; other site
879088002155	Walker B motif; other site
879088002156	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
879088002157	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
879088002158	N-acetyl-D-glucosamine binding site [chemical binding]; other site
879088002159	catalytic residue [active]
879088002160	Predicted transcriptional regulators [Transcription]; Region: COG1695
879088002161	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
879088002162	Protein of unknown function (DUF1048); Region: DUF1048; pfam06304
879088002163	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
879088002164	pyruvate oxidase; Provisional; Region: PRK08611
879088002165	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
879088002166	PYR/PP interface [polypeptide binding]; other site
879088002167	dimer interface [polypeptide binding]; other site
879088002168	tetramer interface [polypeptide binding]; other site
879088002169	TPP binding site [chemical binding]; other site
879088002170	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
879088002171	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
879088002172	TPP-binding site [chemical binding]; other site
879088002173	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
879088002174	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
879088002175	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088002176	dimerization interface [polypeptide binding]; other site
879088002177	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
879088002178	dimer interface [polypeptide binding]; other site
879088002179	putative CheW interface [polypeptide binding]; other site
879088002180	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
879088002181	putative active site [active]
879088002182	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
879088002183	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
879088002184	glutaminase active site [active]
879088002185	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
879088002186	dimer interface [polypeptide binding]; other site
879088002187	active site
879088002188	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
879088002189	dimer interface [polypeptide binding]; other site
879088002190	active site
879088002191	FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196
879088002192	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
879088002193	active site
879088002194	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
879088002195	GIY-YIG motif/motif A; other site
879088002196	Leucine rich repeat; Region: LRR_8; pfam13855
879088002197	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002198	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002199	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002200	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
879088002201	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088002202	non-specific DNA binding site [nucleotide binding]; other site
879088002203	salt bridge; other site
879088002204	sequence-specific DNA binding site [nucleotide binding]; other site
879088002205	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088002206	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088002207	ligand binding site [chemical binding]; other site
879088002208	flexible hinge region; other site
879088002209	Predicted transcriptional regulators [Transcription]; Region: COG1725
879088002210	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002211	DNA-binding site [nucleotide binding]; DNA binding site
879088002212	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
879088002213	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088002214	Walker A/P-loop; other site
879088002215	ATP binding site [chemical binding]; other site
879088002216	Q-loop/lid; other site
879088002217	ABC transporter signature motif; other site
879088002218	Walker B; other site
879088002219	D-loop; other site
879088002220	H-loop/switch region; other site
879088002221	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088002222	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088002223	Walker A/P-loop; other site
879088002224	ATP binding site [chemical binding]; other site
879088002225	Q-loop/lid; other site
879088002226	ABC transporter signature motif; other site
879088002227	Walker B; other site
879088002228	D-loop; other site
879088002229	H-loop/switch region; other site
879088002230	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088002231	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088002232	FtsX-like permease family; Region: FtsX; pfam02687
879088002233	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
879088002234	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088002235	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
879088002236	ligand binding site [chemical binding]; other site
879088002237	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
879088002238	non-specific DNA interactions [nucleotide binding]; other site
879088002239	DNA binding site [nucleotide binding]
879088002240	sequence specific DNA binding site [nucleotide binding]; other site
879088002241	putative cAMP binding site [chemical binding]; other site
879088002242	SnoaL-like domain; Region: SnoaL_4; pfam13577
879088002243	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
879088002244	active site
879088002245	catalytic triad [active]
879088002246	oxyanion hole [active]
879088002247	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088002248	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088002249	Walker A/P-loop; other site
879088002250	ATP binding site [chemical binding]; other site
879088002251	Q-loop/lid; other site
879088002252	ABC transporter signature motif; other site
879088002253	Walker B; other site
879088002254	D-loop; other site
879088002255	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
879088002256	H-loop/switch region; other site
879088002257	active site
879088002258	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
879088002259	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
879088002260	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
879088002261	Zn binding site [ion binding]; other site
879088002262	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
879088002263	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088002264	Zn binding site [ion binding]; other site
879088002265	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
879088002266	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088002267	Zn binding site [ion binding]; other site
879088002268	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
879088002269	Zn binding site [ion binding]; other site
879088002270	Predicted esterase [General function prediction only]; Region: COG0400
879088002271	putative hydrolase; Provisional; Region: PRK11460
879088002272	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
879088002273	GTPases [General function prediction only]; Region: HflX; COG2262
879088002274	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
879088002275	HflX GTPase family; Region: HflX; cd01878
879088002276	G1 box; other site
879088002277	GTP/Mg2+ binding site [chemical binding]; other site
879088002278	Switch I region; other site
879088002279	G2 box; other site
879088002280	G3 box; other site
879088002281	Switch II region; other site
879088002282	G4 box; other site
879088002283	G5 box; other site
879088002284	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
879088002285	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
879088002286	putative active site [active]
879088002287	putative metal binding site [ion binding]; other site
879088002288	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
879088002289	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
879088002290	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
879088002291	Transcriptional regulators [Transcription]; Region: GntR; COG1802
879088002292	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002293	DNA-binding site [nucleotide binding]; DNA binding site
879088002294	Yhfp putative quinone oxidoreductases; Region: MDR_yhfp_like; cd08289
879088002295	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
879088002296	putative NADP binding site [chemical binding]; other site
879088002297	putative dimer interface [polypeptide binding]; other site
879088002298	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
879088002299	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
879088002300	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088002301	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088002302	nucleotide binding site [chemical binding]; other site
879088002303	Predicted membrane protein [Function unknown]; Region: COG4811
879088002304	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
879088002305	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
879088002306	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
879088002307	active site
879088002308	phosphorylation site [posttranslational modification]
879088002309	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088002310	active pocket/dimerization site; other site
879088002311	active site
879088002312	phosphorylation site [posttranslational modification]
879088002313	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
879088002314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088002315	Walker A motif; other site
879088002316	ATP binding site [chemical binding]; other site
879088002317	Walker B motif; other site
879088002318	arginine finger; other site
879088002319	Transcriptional antiterminator [Transcription]; Region: COG3933
879088002320	PRD domain; Region: PRD; pfam00874
879088002321	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088002322	active pocket/dimerization site; other site
879088002323	active site
879088002324	phosphorylation site [posttranslational modification]
879088002325	PRD domain; Region: PRD; pfam00874
879088002326	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
879088002327	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
879088002328	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
879088002329	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
879088002330	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
879088002331	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
879088002332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
879088002333	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
879088002334	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
879088002335	Leucine rich repeat; Region: LRR_8; pfam13855
879088002336	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002337	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002338	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002339	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002340	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002341	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088002342	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
879088002343	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
879088002344	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
879088002345	putative deacylase active site [active]
879088002346	Predicted amidohydrolase [General function prediction only]; Region: COG0388
879088002347	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
879088002348	active site
879088002349	catalytic triad [active]
879088002350	dimer interface [polypeptide binding]; other site
879088002351	Protein of unknown function (DUF554); Region: DUF554; pfam04474
879088002352	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
879088002353	NADH(P)-binding; Region: NAD_binding_10; pfam13460
879088002354	NAD binding site [chemical binding]; other site
879088002355	substrate binding site [chemical binding]; other site
879088002356	putative active site [active]
879088002357	Predicted permeases [General function prediction only]; Region: RarD; COG2962
879088002358	EamA-like transporter family; Region: EamA; pfam00892
879088002359	Uncharacterized conserved protein [Function unknown]; Region: COG2353
879088002360	Transcriptional regulators [Transcription]; Region: MarR; COG1846
879088002361	MarR family; Region: MarR_2; pfam12802
879088002362	lysine transporter; Provisional; Region: PRK10836
879088002363	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
879088002364	PAS domain; Region: PAS_9; pfam13426
879088002365	putative active site [active]
879088002366	heme pocket [chemical binding]; other site
879088002367	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088002368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
879088002369	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
879088002370	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
879088002371	synthetase active site [active]
879088002372	NTP binding site [chemical binding]; other site
879088002373	metal binding site [ion binding]; metal-binding site
879088002374	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
879088002375	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
879088002376	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088002377	non-specific DNA binding site [nucleotide binding]; other site
879088002378	salt bridge; other site
879088002379	sequence-specific DNA binding site [nucleotide binding]; other site
879088002380	Cupin domain; Region: Cupin_2; pfam07883
879088002381	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
879088002382	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
879088002383	Walker A/P-loop; other site
879088002384	ATP binding site [chemical binding]; other site
879088002385	Q-loop/lid; other site
879088002386	ABC transporter signature motif; other site
879088002387	Walker B; other site
879088002388	D-loop; other site
879088002389	H-loop/switch region; other site
879088002390	TOBE domain; Region: TOBE_2; pfam08402
879088002391	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
879088002392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088002393	putative PBP binding loops; other site
879088002394	ABC-ATPase subunit interface; other site
879088002395	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
879088002396	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088002397	dimer interface [polypeptide binding]; other site
879088002398	conserved gate region; other site
879088002399	putative PBP binding loops; other site
879088002400	ABC-ATPase subunit interface; other site
879088002401	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
879088002402	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
879088002403	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
879088002404	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
879088002405	active site
879088002406	zinc binding site [ion binding]; other site
879088002407	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
879088002408	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088002409	Zn2+ binding site [ion binding]; other site
879088002410	Mg2+ binding site [ion binding]; other site
879088002411	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088002412	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088002413	nucleotide binding site [chemical binding]; other site
879088002414	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
879088002415	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
879088002416	FMN binding site [chemical binding]; other site
879088002417	substrate binding site [chemical binding]; other site
879088002418	putative catalytic residue [active]
879088002419	Protein of unknown function (DUF3130; Region: DUF3130; pfam11328
879088002420	LXG domain of WXG superfamily; Region: LXG; pfam04740
879088002421	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
879088002422	dimer interface [polypeptide binding]; other site
879088002423	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088002424	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
879088002425	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
879088002426	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088002427	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
879088002428	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088002429	motif II; other site
879088002430	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
879088002431	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088002432	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088002433	Coenzyme A binding pocket [chemical binding]; other site
879088002434	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
879088002435	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088002436	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088002437	DNA binding residues [nucleotide binding]
879088002438	putative dimer interface [polypeptide binding]; other site
879088002439	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088002440	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088002441	active site
879088002442	catalytic tetrad [active]
879088002443	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
879088002444	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
879088002445	homodimer interface [polypeptide binding]; other site
879088002446	catalytic residues [active]
879088002447	NAD binding site [chemical binding]; other site
879088002448	substrate binding pocket [chemical binding]; other site
879088002449	flexible flap; other site
879088002450	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
879088002451	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
879088002452	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
879088002453	PhoU domain; Region: PhoU; pfam01895
879088002454	PhoU domain; Region: PhoU; pfam01895
879088002455	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
879088002456	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
879088002457	dimer interface [polypeptide binding]; other site
879088002458	PYR/PP interface [polypeptide binding]; other site
879088002459	TPP binding site [chemical binding]; other site
879088002460	substrate binding site [chemical binding]; other site
879088002461	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
879088002462	Domain of unknown function; Region: EKR; smart00890
879088002463	4Fe-4S binding domain; Region: Fer4_6; pfam12837
879088002464	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
879088002465	TPP-binding site [chemical binding]; other site
879088002466	dimer interface [polypeptide binding]; other site
879088002467	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
879088002468	Predicted permeases [General function prediction only]; Region: COG0679
879088002469	Helix-turn-helix domain; Region: HTH_28; pfam13518
879088002470	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088002471	non-specific DNA binding site [nucleotide binding]; other site
879088002472	salt bridge; other site
879088002473	sequence-specific DNA binding site [nucleotide binding]; other site
879088002474	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
879088002475	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002476	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088002477	Predicted membrane protein [Function unknown]; Region: COG3223
879088002478	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088002479	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088002480	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
879088002481	Walker A/P-loop; other site
879088002482	ATP binding site [chemical binding]; other site
879088002483	Q-loop/lid; other site
879088002484	ABC transporter signature motif; other site
879088002485	Walker B; other site
879088002486	D-loop; other site
879088002487	H-loop/switch region; other site
879088002488	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
879088002489	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002490	putative substrate translocation pore; other site
879088002491	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002493	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088002494	putative substrate translocation pore; other site
879088002495	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088002496	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088002497	putative DNA binding site [nucleotide binding]; other site
879088002498	putative Zn2+ binding site [ion binding]; other site
879088002499	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
879088002500	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
879088002501	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088002502	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
879088002503	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088002504	motif II; other site
879088002505	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
879088002506	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002507	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002508	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002509	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002510	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002511	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002512	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088002513	Predicted membrane protein [Function unknown]; Region: COG3326
879088002514	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
879088002515	homotrimer interaction site [polypeptide binding]; other site
879088002516	putative active site [active]
879088002517	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
879088002518	substrate binding site [chemical binding]; other site
879088002519	zinc-binding site [ion binding]; other site
879088002520	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
879088002521	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
879088002522	GIY-YIG motif/motif A; other site
879088002523	active site
879088002524	catalytic site [active]
879088002525	putative DNA binding site [nucleotide binding]; other site
879088002526	metal binding site [ion binding]; metal-binding site
879088002527	UvrB/uvrC motif; Region: UVR; pfam02151
879088002528	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
879088002529	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
879088002530	substrate binding pocket [chemical binding]; other site
879088002531	membrane-bound complex binding site; other site
879088002532	hinge residues; other site
879088002533	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
879088002534	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088002535	dimer interface [polypeptide binding]; other site
879088002536	conserved gate region; other site
879088002537	putative PBP binding loops; other site
879088002538	ABC-ATPase subunit interface; other site
879088002539	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
879088002540	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
879088002541	Walker A/P-loop; other site
879088002542	ATP binding site [chemical binding]; other site
879088002543	Q-loop/lid; other site
879088002544	ABC transporter signature motif; other site
879088002545	Walker B; other site
879088002546	D-loop; other site
879088002547	H-loop/switch region; other site
879088002548	amidase; Provisional; Region: PRK11910
879088002549	Amidase; Region: Amidase; cl11426
879088002550	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088002551	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088002552	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
879088002553	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
879088002554	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
879088002555	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
879088002556	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
879088002557	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
879088002558	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
879088002559	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
879088002560	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
879088002561	Esterase/lipase [General function prediction only]; Region: COG1647
879088002562	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088002563	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088002564	DNA binding site [nucleotide binding]
879088002565	domain linker motif; other site
879088002566	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_1; cd06277
879088002567	putative dimerization interface [polypeptide binding]; other site
879088002568	putative ligand binding site [chemical binding]; other site
879088002569	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
879088002570	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088002571	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
879088002572	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088002573	dimer interface [polypeptide binding]; other site
879088002574	conserved gate region; other site
879088002575	putative PBP binding loops; other site
879088002576	ABC-ATPase subunit interface; other site
879088002577	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088002578	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088002579	dimer interface [polypeptide binding]; other site
879088002580	conserved gate region; other site
879088002581	ABC-ATPase subunit interface; other site
879088002582	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
879088002583	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
879088002584	Ca binding site [ion binding]; other site
879088002585	active site
879088002586	catalytic site [active]
879088002587	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
879088002588	Predicted glycosylase [Carbohydrate transport and metabolism]; Region: COG2152
879088002589	active site
879088002590	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
879088002591	active site
879088002592	substrate binding site [chemical binding]; other site
879088002593	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
879088002594	metal binding site [ion binding]; metal-binding site
879088002595	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
879088002596	DEAD-like helicases superfamily; Region: DEXDc; smart00487
879088002597	ATP binding site [chemical binding]; other site
879088002598	Mg++ binding site [ion binding]; other site
879088002599	motif III; other site
879088002600	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088002601	nucleotide binding region [chemical binding]; other site
879088002602	ATP-binding site [chemical binding]; other site
879088002603	Predicted membrane protein [Function unknown]; Region: COG4708
879088002604	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
879088002605	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4367
879088002606	Predicted transcriptional regulators [Transcription]; Region: COG1733
879088002607	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
879088002608	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
879088002609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002610	putative substrate translocation pore; other site
879088002611	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088002612	PRD domain; Region: PRD; pfam00874
879088002613	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088002614	active site
879088002615	P-loop; other site
879088002616	phosphorylation site [posttranslational modification]
879088002617	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088002618	active site
879088002619	phosphorylation site [posttranslational modification]
879088002620	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088002621	methionine cluster; other site
879088002622	active site
879088002623	phosphorylation site [posttranslational modification]
879088002624	metal binding site [ion binding]; metal-binding site
879088002625	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088002626	active site
879088002627	P-loop; other site
879088002628	phosphorylation site [posttranslational modification]
879088002629	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088002630	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088002631	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
879088002632	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
879088002633	active site
879088002634	trimer interface [polypeptide binding]; other site
879088002635	allosteric site; other site
879088002636	active site lid [active]
879088002637	hexamer (dimer of trimers) interface [polypeptide binding]; other site
879088002638	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088002639	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088002640	active site
879088002641	catalytic tetrad [active]
879088002642	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
879088002643	Collagen binding domain; Region: Collagen_bind; pfam05737
879088002644	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088002645	Uncharacterized conserved protein [Function unknown]; Region: COG3402
879088002646	Predicted membrane protein [Function unknown]; Region: COG3428
879088002647	Bacterial PH domain; Region: DUF304; pfam03703
879088002648	Bacterial PH domain; Region: DUF304; pfam03703
879088002649	Bacterial PH domain; Region: DUF304; pfam03703
879088002650	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
879088002651	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
879088002652	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
879088002653	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
879088002654	active site
879088002655	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
879088002656	dimer interface [polypeptide binding]; other site
879088002657	substrate binding site [chemical binding]; other site
879088002658	catalytic residues [active]
879088002659	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
879088002660	PemK-like protein; Region: PemK; pfam02452
879088002661	Rsbr N terminal; Region: Rsbr_N; pfam08678
879088002662	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088002663	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088002664	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
879088002665	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
879088002666	ATP binding site [chemical binding]; other site
879088002667	Mg2+ binding site [ion binding]; other site
879088002668	G-X-G motif; other site
879088002669	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
879088002670	Phosphoserine phosphatase RsbU, N-terminal domain; Region: RsbU_N; pfam08673
879088002671	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
879088002672	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
879088002673	anti sigma factor interaction site; other site
879088002674	regulatory phosphorylation site [posttranslational modification]; other site
879088002675	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
879088002676	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088002677	ATP binding site [chemical binding]; other site
879088002678	Mg2+ binding site [ion binding]; other site
879088002679	G-X-G motif; other site
879088002680	RNA polymerase sigma factor SigB; Validated; Region: PRK08583
879088002681	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
879088002682	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
879088002683	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
879088002684	DNA binding residues [nucleotide binding]
879088002685	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
879088002686	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
879088002687	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
879088002688	Sulfate transporter family; Region: Sulfate_transp; pfam00916
879088002689	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
879088002690	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
879088002691	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
879088002692	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
879088002693	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
879088002694	RNA binding site [nucleotide binding]; other site
879088002695	hypothetical protein; Provisional; Region: PRK04351
879088002696	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
879088002697	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
879088002698	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
879088002699	Uncharacterized conserved protein [Function unknown]; Region: COG5646
879088002700	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088002701	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088002702	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088002703	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002704	DNA-binding site [nucleotide binding]; DNA binding site
879088002705	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
879088002706	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
879088002707	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
879088002708	Predicted protein tyrosine phosphatase [General function prediction only]; Region: COG5350
879088002709	glutathione reductase; Validated; Region: PRK06116
879088002710	glutathione reductase; Validated; Region: PRK06116
879088002711	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088002712	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088002713	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
879088002714	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088002715	catalytic core [active]
879088002716	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
879088002717	Domain of unknown function DUF20; Region: UPF0118; pfam01594
879088002718	Predicted transcriptional regulators [Transcription]; Region: COG1725
879088002719	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002720	DNA-binding site [nucleotide binding]; DNA binding site
879088002721	Predicted membrane protein [General function prediction only]; Region: COG4194
879088002722	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
879088002723	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
879088002724	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
879088002725	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
879088002726	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
879088002727	tetramerization interface [polypeptide binding]; other site
879088002728	NAD(P) binding site [chemical binding]; other site
879088002729	catalytic residues [active]
879088002730	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
879088002731	active site
879088002732	P-loop; other site
879088002733	phosphorylation site [posttranslational modification]
879088002734	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088002735	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088002736	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088002737	methionine cluster; other site
879088002738	active site
879088002739	phosphorylation site [posttranslational modification]
879088002740	metal binding site [ion binding]; metal-binding site
879088002741	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088002742	beta-galactosidase; Region: BGL; TIGR03356
879088002743	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088002744	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088002745	PRD domain; Region: PRD; pfam00874
879088002746	PRD domain; Region: PRD; pfam00874
879088002747	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088002748	active site
879088002749	phosphorylation site [posttranslational modification]
879088002750	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088002751	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
879088002752	ABC transporter; Region: ABC_tran_2; pfam12848
879088002753	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088002754	heme ABC exporter, ATP-binding protein CcmA; Region: ccmA; TIGR01189
879088002755	Predicted permeases [General function prediction only]; Region: COG0701
879088002756	Predicted membrane protein [Function unknown]; Region: COG3689
879088002757	pantothenate kinase; Provisional; Region: PRK05439
879088002758	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
879088002759	ATP-binding site [chemical binding]; other site
879088002760	CoA-binding site [chemical binding]; other site
879088002761	Mg2+-binding site [ion binding]; other site
879088002762	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
879088002763	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088002764	Walker A/P-loop; other site
879088002765	ATP binding site [chemical binding]; other site
879088002766	Q-loop/lid; other site
879088002767	ABC transporter signature motif; other site
879088002768	Walker B; other site
879088002769	D-loop; other site
879088002770	H-loop/switch region; other site
879088002771	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
879088002772	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
879088002773	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088002774	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088002775	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
879088002776	Domain of unknown function (DUF373); Region: DUF373; cl12079
879088002777	Sulfatase; Region: Sulfatase; pfam00884
879088002778	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
879088002779	active site
879088002780	DNA binding site [nucleotide binding]
879088002781	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
879088002782	active site
879088002783	catalytic site [active]
879088002784	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
879088002785	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
879088002786	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
879088002787	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
879088002788	Uncharacterized conserved protein [Function unknown]; Region: COG0398
879088002789	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
879088002790	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
879088002791	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
879088002792	epoxyqueuosine reductase; Region: TIGR00276
879088002793	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
879088002794	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
879088002795	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
879088002796	dimer interface [polypeptide binding]; other site
879088002797	FMN binding site [chemical binding]; other site
879088002798	NADPH bind site [chemical binding]; other site
879088002799	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
879088002800	Low molecular weight phosphatase family; Region: LMWPc; cd00115
879088002801	active site
879088002802	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
879088002803	HSP90 family protein; Provisional; Region: PRK14083
879088002804	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088002805	ATP binding site [chemical binding]; other site
879088002806	Mg2+ binding site [ion binding]; other site
879088002807	G-X-G motif; other site
879088002808	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
879088002809	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
879088002810	dimerization interface [polypeptide binding]; other site
879088002811	DPS ferroxidase diiron center [ion binding]; other site
879088002812	ion pore; other site
879088002813	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4841
879088002814	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
879088002815	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088002816	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
879088002817	Protein of unknown function (DUF3006); Region: DUF3006; pfam11213
879088002818	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
879088002819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002820	putative substrate translocation pore; other site
879088002821	Transcriptional regulators [Transcription]; Region: FadR; COG2186
879088002822	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002823	DNA-binding site [nucleotide binding]; DNA binding site
879088002824	FCD domain; Region: FCD; pfam07729
879088002825	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
879088002826	Domain of unknown function DUF20; Region: UPF0118; pfam01594
879088002827	Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814
879088002828	PGAP1-like protein; Region: PGAP1; pfam07819
879088002829	Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814
879088002830	Protein of unknown function (DUF4064); Region: DUF4064; pfam13273
879088002831	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
879088002832	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
879088002833	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
879088002834	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
879088002835	active site
879088002836	dimer interface [polypeptide binding]; other site
879088002837	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
879088002838	active site
879088002839	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
879088002840	active site
879088002841	trimer interface [polypeptide binding]; other site
879088002842	allosteric site; other site
879088002843	active site lid [active]
879088002844	hexamer (dimer of trimers) interface [polypeptide binding]; other site
879088002845	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088002846	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088002847	DNA-binding site [nucleotide binding]; DNA binding site
879088002848	UTRA domain; Region: UTRA; pfam07702
879088002849	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
879088002850	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
879088002851	Mg++ binding site [ion binding]; other site
879088002852	putative catalytic motif [active]
879088002853	substrate binding site [chemical binding]; other site
879088002854	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
879088002855	Peptidase family U32; Region: Peptidase_U32; pfam01136
879088002856	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
879088002857	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
879088002858	Peptidase family U32; Region: Peptidase_U32; pfam01136
879088002859	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
879088002860	heat shock protein HtpX; Provisional; Region: PRK04897
879088002861	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
879088002862	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
879088002863	catalytic residues [active]
879088002864	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
879088002865	putative active site [active]
879088002866	putative metal binding residues [ion binding]; other site
879088002867	signature motif; other site
879088002868	putative triphosphate binding site [ion binding]; other site
879088002869	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088002870	TPR motif; other site
879088002871	binding surface
879088002872	Tetratrico peptide repeat; Region: TPR_5; pfam12688
879088002873	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
879088002874	synthetase active site [active]
879088002875	NTP binding site [chemical binding]; other site
879088002876	metal binding site [ion binding]; metal-binding site
879088002877	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
879088002878	ATP-NAD kinase; Region: NAD_kinase; pfam01513
879088002879	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
879088002880	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
879088002881	active site
879088002882	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594
879088002883	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
879088002884	NAD binding site [chemical binding]; other site
879088002885	homotetramer interface [polypeptide binding]; other site
879088002886	homodimer interface [polypeptide binding]; other site
879088002887	substrate binding site [chemical binding]; other site
879088002888	active site
879088002889	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
879088002890	DltD N-terminal region; Region: DltD_N; pfam04915
879088002891	DltD central region; Region: DltD_M; pfam04918
879088002892	DltD C-terminal region; Region: DltD_C; pfam04914
879088002893	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
879088002894	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
879088002895	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
879088002896	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
879088002897	acyl-activating enzyme (AAE) consensus motif; other site
879088002898	AMP binding site [chemical binding]; other site
879088002899	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
879088002900	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
879088002901	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088002902	active site
879088002903	dimer interface [polypeptide binding]; other site
879088002904	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088002905	Coenzyme A binding pocket [chemical binding]; other site
879088002906	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
879088002907	Putative esterase; Region: Esterase; pfam00756
879088002908	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
879088002909	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
879088002910	homodimer interface [polypeptide binding]; other site
879088002911	substrate-cofactor binding pocket; other site
879088002912	catalytic residue [active]
879088002913	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
879088002914	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088002915	Walker A/P-loop; other site
879088002916	ATP binding site [chemical binding]; other site
879088002917	Q-loop/lid; other site
879088002918	ABC transporter signature motif; other site
879088002919	Walker B; other site
879088002920	D-loop; other site
879088002921	H-loop/switch region; other site
879088002922	ABC-2 type transporter; Region: ABC2_membrane; cl17235
879088002923	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
879088002924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088002925	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088002926	putative substrate translocation pore; other site
879088002927	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
879088002928	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
879088002929	putative oligomer interface [polypeptide binding]; other site
879088002930	putative active site [active]
879088002931	metal binding site [ion binding]; metal-binding site
879088002932	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
879088002933	catalytic residues [active]
879088002934	dimer interface [polypeptide binding]; other site
879088002935	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
879088002936	LytTr DNA-binding domain; Region: LytTR; pfam04397
879088002937	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088002938	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088002939	Walker A/P-loop; other site
879088002940	ATP binding site [chemical binding]; other site
879088002941	Q-loop/lid; other site
879088002942	ABC transporter signature motif; other site
879088002943	Walker B; other site
879088002944	D-loop; other site
879088002945	H-loop/switch region; other site
879088002946	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cl09829
879088002947	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
879088002948	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
879088002949	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
879088002950	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
879088002951	G1 box; other site
879088002952	putative GEF interaction site [polypeptide binding]; other site
879088002953	GTP/Mg2+ binding site [chemical binding]; other site
879088002954	Switch I region; other site
879088002955	G2 box; other site
879088002956	G3 box; other site
879088002957	Switch II region; other site
879088002958	G4 box; other site
879088002959	G5 box; other site
879088002960	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
879088002961	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088002962	MarR family; Region: MarR_2; cl17246
879088002963	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
879088002964	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
879088002965	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
879088002966	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
879088002967	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
879088002968	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
879088002969	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
879088002970	Acyltransferase family; Region: Acyl_transf_3; pfam01757
879088002971	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
879088002972	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
879088002973	DNA binding site [nucleotide binding]
879088002974	active site
879088002975	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088002976	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
879088002977	Walker A motif; other site
879088002978	ATP binding site [chemical binding]; other site
879088002979	Walker B motif; other site
879088002980	arginine finger; other site
879088002981	UvrB/uvrC motif; Region: UVR; pfam02151
879088002982	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088002983	Walker A motif; other site
879088002984	ATP binding site [chemical binding]; other site
879088002985	Walker B motif; other site
879088002986	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
879088002987	CAAX protease self-immunity; Region: Abi; pfam02517
879088002988	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
879088002989	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
879088002990	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
879088002991	nucleotide binding site [chemical binding]; other site
879088002992	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4873
879088002993	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
879088002994	dimerization domain swap beta strand [polypeptide binding]; other site
879088002995	regulatory protein interface [polypeptide binding]; other site
879088002996	active site
879088002997	regulatory phosphorylation site [posttranslational modification]; other site
879088002998	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
879088002999	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
879088003000	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
879088003001	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
879088003002	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
879088003003	Uncharacterized conserved protein [Function unknown]; Region: COG1434
879088003004	putative active site [active]
879088003005	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
879088003006	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
879088003007	aminotransferase A; Validated; Region: PRK07683
879088003008	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088003009	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088003010	homodimer interface [polypeptide binding]; other site
879088003011	catalytic residue [active]
879088003012	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4703
879088003013	FOG: CBS domain [General function prediction only]; Region: COG0517
879088003014	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
879088003015	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088003016	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088003017	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
879088003018	dimerization interface [polypeptide binding]; other site
879088003019	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
879088003020	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
879088003021	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
879088003022	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
879088003023	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
879088003024	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
879088003025	metal binding site [ion binding]; metal-binding site
879088003026	putative dimer interface [polypeptide binding]; other site
879088003027	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
879088003028	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
879088003029	Mechanosensitive ion channel; Region: MS_channel; pfam00924
879088003030	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
879088003031	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088003032	Walker A/P-loop; other site
879088003033	ATP binding site [chemical binding]; other site
879088003034	Q-loop/lid; other site
879088003035	ABC transporter signature motif; other site
879088003036	Walker B; other site
879088003037	D-loop; other site
879088003038	H-loop/switch region; other site
879088003039	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
879088003040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088003041	dimer interface [polypeptide binding]; other site
879088003042	conserved gate region; other site
879088003043	putative PBP binding loops; other site
879088003044	ABC-ATPase subunit interface; other site
879088003045	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
879088003046	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
879088003047	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
879088003048	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
879088003049	HPr interaction site; other site
879088003050	glycerol kinase (GK) interaction site [polypeptide binding]; other site
879088003051	active site
879088003052	phosphorylation site [posttranslational modification]
879088003053	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
879088003054	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
879088003055	S1 domain; Region: S1_2; pfam13509
879088003056	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
879088003057	RNA binding site [nucleotide binding]; other site
879088003058	Predicted membrane protein [Function unknown]; Region: COG4758
879088003059	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
879088003060	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
879088003061	Histidine kinase; Region: HisKA_3; pfam07730
879088003062	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088003063	ATP binding site [chemical binding]; other site
879088003064	Mg2+ binding site [ion binding]; other site
879088003065	G-X-G motif; other site
879088003066	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
879088003067	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088003068	active site
879088003069	phosphorylation site [posttranslational modification]
879088003070	intermolecular recognition site; other site
879088003071	dimerization interface [polypeptide binding]; other site
879088003072	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
879088003073	DNA binding residues [nucleotide binding]
879088003074	dimerization interface [polypeptide binding]; other site
879088003075	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
879088003076	TrkA-N domain; Region: TrkA_N; pfam02254
879088003077	TrkA-C domain; Region: TrkA_C; pfam02080
879088003078	Predicted membrane protein [Function unknown]; Region: COG1289
879088003079	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
879088003080	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
879088003081	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
879088003082	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
879088003083	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
879088003084	hypothetical protein; Provisional; Region: PRK13667
879088003085	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088003086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088003087	active site
879088003088	motif I; other site
879088003089	motif II; other site
879088003090	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088003091	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088003092	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088003093	DNA binding site [nucleotide binding]
879088003094	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
879088003095	ligand binding site [chemical binding]; other site
879088003096	dimerization interface [polypeptide binding]; other site
879088003097	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
879088003098	hexamer (dimer of trimers) interface [polypeptide binding]; other site
879088003099	trimer interface [polypeptide binding]; other site
879088003100	substrate binding site [chemical binding]; other site
879088003101	Mn binding site [ion binding]; other site
879088003102	transketolase; Reviewed; Region: PRK05899
879088003103	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
879088003104	TPP-binding site [chemical binding]; other site
879088003105	dimer interface [polypeptide binding]; other site
879088003106	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
879088003107	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
879088003108	PYR/PP interface [polypeptide binding]; other site
879088003109	dimer interface [polypeptide binding]; other site
879088003110	TPP binding site [chemical binding]; other site
879088003111	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088003112	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
879088003113	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
879088003114	nucleotide binding site [chemical binding]; other site
879088003115	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
879088003116	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
879088003117	active site turn [active]
879088003118	phosphorylation site [posttranslational modification]
879088003119	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
879088003120	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
879088003121	HPr interaction site; other site
879088003122	glycerol kinase (GK) interaction site [polypeptide binding]; other site
879088003123	active site
879088003124	phosphorylation site [posttranslational modification]
879088003125	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
879088003126	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
879088003127	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
879088003128	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
879088003129	GTP binding site; other site
879088003130	ATP-binding cassette domain of the molybdenum transport system; Region: ABC_ModC_molybdenum_transporter; cd03297
879088003131	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
879088003132	Walker A/P-loop; other site
879088003133	ATP binding site [chemical binding]; other site
879088003134	Q-loop/lid; other site
879088003135	ABC transporter signature motif; other site
879088003136	Walker B; other site
879088003137	D-loop; other site
879088003138	H-loop/switch region; other site
879088003139	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088003140	dimer interface [polypeptide binding]; other site
879088003141	conserved gate region; other site
879088003142	putative PBP binding loops; other site
879088003143	ABC-ATPase subunit interface; other site
879088003144	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
879088003145	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
879088003146	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
879088003147	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
879088003148	dimer interface [polypeptide binding]; other site
879088003149	putative functional site; other site
879088003150	putative MPT binding site; other site
879088003151	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
879088003152	Walker A motif; other site
879088003153	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
879088003154	MoaE homodimer interface [polypeptide binding]; other site
879088003155	MoaD interaction [polypeptide binding]; other site
879088003156	active site residues [active]
879088003157	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
879088003158	MoaE interaction surface [polypeptide binding]; other site
879088003159	MoeB interaction surface [polypeptide binding]; other site
879088003160	thiocarboxylated glycine; other site
879088003161	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
879088003162	trimer interface [polypeptide binding]; other site
879088003163	dimer interface [polypeptide binding]; other site
879088003164	putative active site [active]
879088003165	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
879088003166	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
879088003167	FeS/SAM binding site; other site
879088003168	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
879088003169	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
879088003170	MPT binding site; other site
879088003171	trimer interface [polypeptide binding]; other site
879088003172	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
879088003173	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
879088003174	ATP binding site [chemical binding]; other site
879088003175	substrate interface [chemical binding]; other site
879088003176	Flavin Reductases; Region: FlaRed; cl00801
879088003177	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
879088003178	active site
879088003179	catalytic residues [active]
879088003180	metal binding site [ion binding]; metal-binding site
879088003181	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
879088003182	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
879088003183	TPP-binding site [chemical binding]; other site
879088003184	tetramer interface [polypeptide binding]; other site
879088003185	heterodimer interface [polypeptide binding]; other site
879088003186	phosphorylation loop region [posttranslational modification]
879088003187	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
879088003188	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
879088003189	alpha subunit interface [polypeptide binding]; other site
879088003190	TPP binding site [chemical binding]; other site
879088003191	heterodimer interface [polypeptide binding]; other site
879088003192	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088003193	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
879088003194	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
879088003195	E3 interaction surface; other site
879088003196	lipoyl attachment site [posttranslational modification]; other site
879088003197	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
879088003198	E3 interaction surface; other site
879088003199	lipoyl attachment site [posttranslational modification]; other site
879088003200	e3 binding domain; Region: E3_binding; pfam02817
879088003201	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
879088003202	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
879088003203	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
879088003204	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088003205	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
879088003206	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
879088003207	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
879088003208	NAD(P) binding site [chemical binding]; other site
879088003209	LDH/MDH dimer interface [polypeptide binding]; other site
879088003210	substrate binding site [chemical binding]; other site
879088003211	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4476
879088003212	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
879088003213	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
879088003214	catalytic residues [active]
879088003215	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
879088003216	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
879088003217	Cl binding site [ion binding]; other site
879088003218	oligomer interface [polypeptide binding]; other site
879088003219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
879088003220	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
879088003221	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
879088003222	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
879088003223	active site
879088003224	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
879088003225	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
879088003226	G1 box; other site
879088003227	putative GEF interaction site [polypeptide binding]; other site
879088003228	GTP/Mg2+ binding site [chemical binding]; other site
879088003229	Switch I region; other site
879088003230	G2 box; other site
879088003231	G3 box; other site
879088003232	Switch II region; other site
879088003233	G4 box; other site
879088003234	G5 box; other site
879088003235	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
879088003236	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
879088003237	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4896
879088003238	hypothetical protein; Provisional; Region: PRK13666
879088003239	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
879088003240	pyruvate carboxylase; Reviewed; Region: PRK12999
879088003241	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
879088003242	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
879088003243	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
879088003244	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
879088003245	active site
879088003246	catalytic residues [active]
879088003247	metal binding site [ion binding]; metal-binding site
879088003248	homodimer binding site [polypeptide binding]; other site
879088003249	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
879088003250	carboxyltransferase (CT) interaction site; other site
879088003251	biotinylation site [posttranslational modification]; other site
879088003252	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
879088003253	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
879088003254	putative binding site residues; other site
879088003255	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
879088003256	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
879088003257	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
879088003258	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
879088003259	Walker A/P-loop; other site
879088003260	ATP binding site [chemical binding]; other site
879088003261	Q-loop/lid; other site
879088003262	ABC transporter signature motif; other site
879088003263	Walker B; other site
879088003264	D-loop; other site
879088003265	H-loop/switch region; other site
879088003266	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088003267	SH3-like domain; Region: SH3_8; pfam13457
879088003268	SH3-like domain; Region: SH3_8; pfam13457
879088003269	SH3-like domain; Region: SH3_8; pfam13457
879088003270	SH3-like domain; Region: SH3_8; pfam13457
879088003271	SH3-like domain; Region: SH3_8; pfam13457
879088003272	SH3-like domain; Region: SH3_8; pfam13457
879088003273	SH3-like domain; Region: SH3_8; pfam13457
879088003274	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
879088003275	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
879088003276	Ligand binding site; other site
879088003277	Putative Catalytic site; other site
879088003278	DXD motif; other site
879088003279	conserved hypothetical integral membrane protein; Region: TIGR03766
879088003280	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
879088003281	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
879088003282	active site
879088003283	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
879088003284	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
879088003285	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
879088003286	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
879088003287	active site
879088003288	tetramer interface; other site
879088003289	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
879088003290	substrate binding site; other site
879088003291	dimer interface; other site
879088003292	ribitol-5-phosphate dehydrogenase; Region: ribitol-5-phosphate_DH; cd08237
879088003293	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
879088003294	putative NAD(P) binding site [chemical binding]; other site
879088003295	putative catalytic Zn binding site [ion binding]; other site
879088003296	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
879088003297	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
879088003298	active site
879088003299	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
879088003300	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
879088003301	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
879088003302	glycerol-3-phosphate cytidylyltransferase; Region: G3P_Cytidylyltransferase; cd02171
879088003303	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
879088003304	active site
879088003305	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
879088003306	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
879088003307	active site
879088003308	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
879088003309	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
879088003310	homodimer interface [polypeptide binding]; other site
879088003311	NAD binding pocket [chemical binding]; other site
879088003312	ATP binding pocket [chemical binding]; other site
879088003313	Mg binding site [ion binding]; other site
879088003314	active-site loop [active]
879088003315	Uncharacterized conserved protein [Function unknown]; Region: COG1359
879088003316	Phosphotransferase system cellobiose-specific component IIB [Carbohydrate transport and metabolism]; Region: CelA; COG1440
879088003317	active site
879088003318	P-loop; other site
879088003319	phosphorylation site [posttranslational modification]
879088003320	GMP synthase; Reviewed; Region: guaA; PRK00074
879088003321	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
879088003322	AMP/PPi binding site [chemical binding]; other site
879088003323	candidate oxyanion hole; other site
879088003324	catalytic triad [active]
879088003325	potential glutamine specificity residues [chemical binding]; other site
879088003326	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
879088003327	ATP Binding subdomain [chemical binding]; other site
879088003328	Dimerization subdomain; other site
879088003329	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
879088003330	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088003331	active site
879088003332	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
879088003333	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088003334	Walker A/P-loop; other site
879088003335	ATP binding site [chemical binding]; other site
879088003336	Q-loop/lid; other site
879088003337	ABC transporter signature motif; other site
879088003338	Walker B; other site
879088003339	D-loop; other site
879088003340	H-loop/switch region; other site
879088003341	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
879088003342	putative FMN binding site [chemical binding]; other site
879088003343	NADPH bind site [chemical binding]; other site
879088003344	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
879088003345	YcaO-like family; Region: YcaO; pfam02624
879088003346	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
879088003347	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003348	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088003349	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003350	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
879088003351	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088003352	active site
879088003353	Protein of unknown function (DUF3130; Region: DUF3130; cl12867
879088003354	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
879088003355	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
879088003356	MepB protein; Region: MepB; cl01985
879088003357	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
879088003358	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088003359	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088003360	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088003361	Coenzyme A binding pocket [chemical binding]; other site
879088003362	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088003363	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
879088003364	DNA binding residues [nucleotide binding]
879088003365	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
879088003366	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088003367	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088003368	Walker A/P-loop; other site
879088003369	ATP binding site [chemical binding]; other site
879088003370	Q-loop/lid; other site
879088003371	ABC transporter signature motif; other site
879088003372	Walker B; other site
879088003373	D-loop; other site
879088003374	H-loop/switch region; other site
879088003375	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088003376	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088003377	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088003378	Walker A/P-loop; other site
879088003379	ATP binding site [chemical binding]; other site
879088003380	Q-loop/lid; other site
879088003381	ABC transporter signature motif; other site
879088003382	Walker B; other site
879088003383	D-loop; other site
879088003384	H-loop/switch region; other site
879088003385	Uncharacterized conserved protein [Function unknown]; Region: COG1359
879088003386	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088003387	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088003388	DNA binding residues [nucleotide binding]
879088003389	putative dimer interface [polypeptide binding]; other site
879088003390	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
879088003391	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
879088003392	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088003393	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088003394	LRR adjacent; Region: LRR_adjacent; pfam08191
879088003395	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088003396	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
879088003397	Clp protease; Region: CLP_protease; pfam00574
879088003398	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
879088003399	oligomer interface [polypeptide binding]; other site
879088003400	active site residues [active]
879088003401	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
879088003402	dimer interface [polypeptide binding]; other site
879088003403	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088003404	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
879088003405	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
879088003406	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
879088003407	SLBB domain; Region: SLBB; pfam10531
879088003408	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
879088003409	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
879088003410	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
879088003411	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
879088003412	putative hexamer interface [polypeptide binding]; other site
879088003413	putative hexagonal pore; other site
879088003414	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
879088003415	putative hexamer interface [polypeptide binding]; other site
879088003416	putative hexagonal pore; other site
879088003417	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
879088003418	putative hexamer interface [polypeptide binding]; other site
879088003419	putative hexagonal pore; other site
879088003420	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
879088003421	G1 box; other site
879088003422	GTP/Mg2+ binding site [chemical binding]; other site
879088003423	G2 box; other site
879088003424	Switch I region; other site
879088003425	G3 box; other site
879088003426	Switch II region; other site
879088003427	G4 box; other site
879088003428	G5 box; other site
879088003429	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
879088003430	homotrimer interface [polypeptide binding]; other site
879088003431	Walker A motif; other site
879088003432	GTP binding site [chemical binding]; other site
879088003433	Walker B motif; other site
879088003434	Cobalamin-5-phosphate synthase [Coenzyme metabolism]; Region: CobS; COG0368
879088003435	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088003436	catalytic core [active]
879088003437	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
879088003438	Sensory domain found in PocR; Region: PocR; pfam10114
879088003439	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003440	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088003441	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003442	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
879088003443	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
879088003444	Hexamer interface [polypeptide binding]; other site
879088003445	Hexagonal pore residue; other site
879088003446	propanediol utilization protein PduB; Provisional; Region: PRK15415
879088003447	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
879088003448	putative hexamer interface [polypeptide binding]; other site
879088003449	putative hexagonal pore; other site
879088003450	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
879088003451	putative hexamer interface [polypeptide binding]; other site
879088003452	putative hexagonal pore; other site
879088003453	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
879088003454	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
879088003455	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
879088003456	alpha-beta subunit interface [polypeptide binding]; other site
879088003457	alpha-gamma subunit interface [polypeptide binding]; other site
879088003458	active site
879088003459	substrate and K+ binding site; other site
879088003460	K+ binding site [ion binding]; other site
879088003461	cobalamin binding site [chemical binding]; other site
879088003462	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
879088003463	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
879088003464	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
879088003465	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
879088003466	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
879088003467	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
879088003468	putative hexamer interface [polypeptide binding]; other site
879088003469	putative hexagonal pore; other site
879088003470	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
879088003471	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
879088003472	Hexamer interface [polypeptide binding]; other site
879088003473	Hexagonal pore residue; other site
879088003474	Propanediol utilization protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduL; COG4869
879088003475	Propanediol utilisation protein PduL; Region: PduL; pfam06130
879088003476	Propanediol utilisation protein PduL; Region: PduL; pfam06130
879088003477	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
879088003478	Cell division protein FtsA; Region: FtsA; cl17206
879088003479	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
879088003480	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
879088003481	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
879088003482	Hexamer/Pentamer interface [polypeptide binding]; other site
879088003483	central pore; other site
879088003484	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
879088003485	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
879088003486	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
879088003487	NAD(P) binding site [chemical binding]; other site
879088003488	catalytic residues [active]
879088003489	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
879088003490	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
879088003491	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
879088003492	putative active site [active]
879088003493	metal binding site [ion binding]; metal-binding site
879088003494	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
879088003495	amphipathic channel; other site
879088003496	Asn-Pro-Ala signature motifs; other site
879088003497	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
879088003498	propionate/acetate kinase; Provisional; Region: PRK12379
879088003499	threonine-phosphate decarboxylase; Provisional; Region: PRK06358
879088003500	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088003501	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088003502	homodimer interface [polypeptide binding]; other site
879088003503	catalytic residue [active]
879088003504	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
879088003505	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
879088003506	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
879088003507	putative active site [active]
879088003508	metal binding site [ion binding]; metal-binding site
879088003509	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
879088003510	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088003511	active site
879088003512	phosphorylation site [posttranslational modification]
879088003513	intermolecular recognition site; other site
879088003514	dimerization interface [polypeptide binding]; other site
879088003515	ANTAR domain; Region: ANTAR; pfam03861
879088003516	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
879088003517	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
879088003518	Histidine kinase; Region: HisKA_2; pfam07568
879088003519	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088003520	ATP binding site [chemical binding]; other site
879088003521	Mg2+ binding site [ion binding]; other site
879088003522	G-X-G motif; other site
879088003523	Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition [Amino acid transport and metabolism]; Region: EutA; COG4819
879088003524	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
879088003525	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
879088003526	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
879088003527	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
879088003528	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
879088003529	putative hexamer interface [polypeptide binding]; other site
879088003530	putative hexagonal pore; other site
879088003531	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
879088003532	putative hexamer interface [polypeptide binding]; other site
879088003533	putative hexagonal pore; other site
879088003534	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
879088003535	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
879088003536	Hexamer interface [polypeptide binding]; other site
879088003537	Hexagonal pore residue; other site
879088003538	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
879088003539	putative catalytic cysteine [active]
879088003540	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
879088003541	Hexamer interface [polypeptide binding]; other site
879088003542	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
879088003543	Ethanolamine utilization cobalamin adenosyltransferase [Amino acid transport and metabolism]; Region: EutT; COG4812
879088003544	Propanediol utilization protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduL; COG4869
879088003545	Propanediol utilisation protein PduL; Region: PduL; pfam06130
879088003546	Propanediol utilisation protein PduL; Region: PduL; pfam06130
879088003547	ethanolamine utilization protein; Region: eut_hyp; TIGR02536
879088003548	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
879088003549	Hexamer/Pentamer interface [polypeptide binding]; other site
879088003550	central pore; other site
879088003551	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
879088003552	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
879088003553	putative hexamer interface [polypeptide binding]; other site
879088003554	putative hexagonal pore; other site
879088003555	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
879088003556	putative hexamer interface [polypeptide binding]; other site
879088003557	putative hexagonal pore; other site
879088003558	Ethanolamine utilisation protein, EutH; Region: EutH; pfam04346
879088003559	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
879088003560	Ethanolamine utilisation protein EutQ; Region: EutQ; pfam06249
879088003561	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003562	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088003563	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088003564	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
879088003565	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
879088003566	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
879088003567	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
879088003568	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
879088003569	catalytic triad [active]
879088003570	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
879088003571	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
879088003572	Precorrin-8X methylmutase; Region: CbiC; pfam02570
879088003573	Cobalamin biosynthesis protein CbiD [Coenzyme metabolism]; Region: CbiD; COG1903
879088003574	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
879088003575	active site
879088003576	putative homodimer interface [polypeptide binding]; other site
879088003577	SAM binding site [chemical binding]; other site
879088003578	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
879088003579	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088003580	S-adenosylmethionine binding site [chemical binding]; other site
879088003581	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
879088003582	active site
879088003583	SAM binding site [chemical binding]; other site
879088003584	homodimer interface [polypeptide binding]; other site
879088003585	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
879088003586	active site
879088003587	SAM binding site [chemical binding]; other site
879088003588	homodimer interface [polypeptide binding]; other site
879088003589	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
879088003590	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
879088003591	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
879088003592	active site
879088003593	SAM binding site [chemical binding]; other site
879088003594	homodimer interface [polypeptide binding]; other site
879088003595	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
879088003596	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
879088003597	active site
879088003598	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
879088003599	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
879088003600	active site
879088003601	C-terminal domain interface [polypeptide binding]; other site
879088003602	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
879088003603	active site
879088003604	N-terminal domain interface [polypeptide binding]; other site
879088003605	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
879088003606	active site
879088003607	SAM binding site [chemical binding]; other site
879088003608	homodimer interface [polypeptide binding]; other site
879088003609	cobalt transport protein CbiM; Validated; Region: PRK08319
879088003610	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
879088003611	ABC-type cobalt transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CbiN; COG1930
879088003612	cobalt transport protein CbiQ; Provisional; Region: PRK15485
879088003613	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
879088003614	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
879088003615	Walker A/P-loop; other site
879088003616	ATP binding site [chemical binding]; other site
879088003617	Q-loop/lid; other site
879088003618	ABC transporter signature motif; other site
879088003619	Walker B; other site
879088003620	D-loop; other site
879088003621	H-loop/switch region; other site
879088003622	cobyric acid synthase; Provisional; Region: PRK00784
879088003623	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
879088003624	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
879088003625	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
879088003626	catalytic triad [active]
879088003627	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
879088003628	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
879088003629	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
879088003630	AAA domain; Region: AAA_17; cl17253
879088003631	Predicted transcriptional regulators [Transcription]; Region: COG1695
879088003632	Transcriptional regulator PadR-like family; Region: PadR; cl17335
879088003633	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
879088003634	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088003635	SH3-like domain; Region: SH3_8; pfam13457
879088003636	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088003637	SH3-like domain; Region: SH3_8; pfam13457
879088003638	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
879088003639	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
879088003640	oligomer interface [polypeptide binding]; other site
879088003641	active site
879088003642	metal binding site [ion binding]; metal-binding site
879088003643	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
879088003644	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
879088003645	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
879088003646	Predicted transcriptional regulators [Transcription]; Region: COG1733
879088003647	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
879088003648	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
879088003649	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
879088003650	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
879088003651	dimer interface [polypeptide binding]; other site
879088003652	motif 1; other site
879088003653	active site
879088003654	motif 2; other site
879088003655	motif 3; other site
879088003656	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
879088003657	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
879088003658	putative tRNA-binding site [nucleotide binding]; other site
879088003659	B3/4 domain; Region: B3_4; pfam03483
879088003660	tRNA synthetase B5 domain; Region: B5; smart00874
879088003661	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
879088003662	dimer interface [polypeptide binding]; other site
879088003663	motif 1; other site
879088003664	motif 3; other site
879088003665	motif 2; other site
879088003666	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
879088003667	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088003668	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088003669	Walker A/P-loop; other site
879088003670	ATP binding site [chemical binding]; other site
879088003671	Q-loop/lid; other site
879088003672	ABC transporter signature motif; other site
879088003673	Walker B; other site
879088003674	D-loop; other site
879088003675	H-loop/switch region; other site
879088003676	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088003677	FtsX-like permease family; Region: FtsX; pfam02687
879088003678	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
879088003679	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088003680	FtsX-like permease family; Region: FtsX; pfam02687
879088003681	Transcriptional regulators [Transcription]; Region: MarR; COG1846
879088003682	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088003683	putative DNA binding site [nucleotide binding]; other site
879088003684	putative Zn2+ binding site [ion binding]; other site
879088003685	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
879088003686	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
879088003687	ligand binding site [chemical binding]; other site
879088003688	active site
879088003689	UGI interface [polypeptide binding]; other site
879088003690	catalytic site [active]
879088003691	ribonuclease HIII; Provisional; Region: PRK00996
879088003692	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
879088003693	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
879088003694	RNA/DNA hybrid binding site [nucleotide binding]; other site
879088003695	active site
879088003696	Cell division protein ZapA; Region: ZapA; cl01146
879088003697	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
879088003698	Colicin V production protein; Region: Colicin_V; pfam02674
879088003699	hypothetical protein; Provisional; Region: PRK08609
879088003700	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
879088003701	active site
879088003702	primer binding site [nucleotide binding]; other site
879088003703	NTP  binding site [chemical binding]; other site
879088003704	metal binding triad [ion binding]; metal-binding site
879088003705	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
879088003706	active site
879088003707	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
879088003708	MutS domain III; Region: MutS_III; pfam05192
879088003709	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088003710	Walker A/P-loop; other site
879088003711	ATP binding site [chemical binding]; other site
879088003712	Q-loop/lid; other site
879088003713	ABC transporter signature motif; other site
879088003714	Walker B; other site
879088003715	D-loop; other site
879088003716	H-loop/switch region; other site
879088003717	Smr domain; Region: Smr; pfam01713
879088003718	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088003719	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
879088003720	catalytic residues [active]
879088003721	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
879088003722	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
879088003723	GIY-YIG motif/motif A; other site
879088003724	active site
879088003725	catalytic site [active]
879088003726	putative DNA binding site [nucleotide binding]; other site
879088003727	metal binding site [ion binding]; metal-binding site
879088003728	UvrB/uvrC motif; Region: UVR; pfam02151
879088003729	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
879088003730	aspartate kinase; Reviewed; Region: PRK06635
879088003731	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
879088003732	putative nucleotide binding site [chemical binding]; other site
879088003733	putative catalytic residues [active]
879088003734	putative Mg ion binding site [ion binding]; other site
879088003735	putative aspartate binding site [chemical binding]; other site
879088003736	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
879088003737	putative allosteric regulatory site; other site
879088003738	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923
879088003739	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
879088003740	Glutamate racemase [Cell envelope biogenesis, outer membrane]; Region: MurI; COG0796
879088003741	ribonuclease PH; Reviewed; Region: rph; PRK00173
879088003742	Ribonuclease PH; Region: RNase_PH_bact; cd11362
879088003743	hexamer interface [polypeptide binding]; other site
879088003744	active site
879088003745	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
879088003746	active site
879088003747	dimerization interface [polypeptide binding]; other site
879088003748	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
879088003749	active site
879088003750	metal binding site [ion binding]; metal-binding site
879088003751	homotetramer interface [polypeptide binding]; other site
879088003752	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088003753	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088003754	LRR adjacent; Region: LRR_adjacent; pfam08191
879088003755	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088003756	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088003757	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088003758	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088003759	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088003760	Uncharacterized conserved protein [Function unknown]; Region: COG5361
879088003761	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
879088003762	Protein of unknown function (DUF1214); Region: DUF1214; pfam06742
879088003763	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
879088003764	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
879088003765	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
879088003766	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
879088003767	dimer interface [polypeptide binding]; other site
879088003768	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088003769	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088003770	catalytic core [active]
879088003771	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
879088003772	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
879088003773	ATP binding site [chemical binding]; other site
879088003774	Mg++ binding site [ion binding]; other site
879088003775	motif III; other site
879088003776	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088003777	nucleotide binding region [chemical binding]; other site
879088003778	ATP-binding site [chemical binding]; other site
879088003779	RNA recognition motif in Bacillus subtilis ATP-dependent RNA helicase YxiN and similar proteins; Region: RRM_BsYxiN_like; cd12500
879088003780	RNA binding site [nucleotide binding]; other site
879088003781	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
879088003782	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
879088003783	putative active site [active]
879088003784	nucleotide binding site [chemical binding]; other site
879088003785	nudix motif; other site
879088003786	putative metal binding site [ion binding]; other site
879088003787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088003788	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088003789	putative substrate translocation pore; other site
879088003790	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088003791	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088003792	ligand binding site [chemical binding]; other site
879088003793	flexible hinge region; other site
879088003794	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088003795	Uncharacterized conserved protein [Function unknown]; Region: COG1284
879088003796	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088003797	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088003798	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
879088003799	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088003800	DNA-binding site [nucleotide binding]; DNA binding site
879088003801	UTRA domain; Region: UTRA; pfam07702
879088003802	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
879088003803	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
879088003804	Ca binding site [ion binding]; other site
879088003805	active site
879088003806	catalytic site [active]
879088003807	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
879088003808	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
879088003809	active site turn [active]
879088003810	phosphorylation site [posttranslational modification]
879088003811	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
879088003812	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_29; cd04688
879088003813	nudix motif; other site
879088003814	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
879088003815	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088003816	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
879088003817	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
879088003818	putative catalytic cysteine [active]
879088003819	Glutamate 5-kinase [Amino acid transport and metabolism]; Region: ProB; COG0263
879088003820	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
879088003821	nucleotide binding site [chemical binding]; other site
879088003822	homotetrameric interface [polypeptide binding]; other site
879088003823	putative phosphate binding site [ion binding]; other site
879088003824	putative allosteric binding site; other site
879088003825	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
879088003826	Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones]; Region: prsW; COG2339
879088003827	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
879088003828	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088003829	non-specific DNA binding site [nucleotide binding]; other site
879088003830	salt bridge; other site
879088003831	sequence-specific DNA binding site [nucleotide binding]; other site
879088003832	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088003833	non-specific DNA binding site [nucleotide binding]; other site
879088003834	salt bridge; other site
879088003835	sequence-specific DNA binding site [nucleotide binding]; other site
879088003836	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
879088003837	active site
879088003838	trigger factor; Provisional; Region: tig; PRK01490
879088003839	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
879088003840	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
879088003841	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
879088003842	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
879088003843	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088003844	Walker A motif; other site
879088003845	ATP binding site [chemical binding]; other site
879088003846	Walker B motif; other site
879088003847	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
879088003848	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
879088003849	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
879088003850	Catalytic site [active]
879088003851	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
879088003852	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
879088003853	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
879088003854	Catalytic site [active]
879088003855	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
879088003856	Signal peptidase, peptidase S26; Region: Peptidase_S26; pfam10502
879088003857	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
879088003858	Catalytic site [active]
879088003859	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
879088003860	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
879088003861	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
879088003862	GTP/Mg2+ binding site [chemical binding]; other site
879088003863	G4 box; other site
879088003864	G5 box; other site
879088003865	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
879088003866	G1 box; other site
879088003867	G1 box; other site
879088003868	GTP/Mg2+ binding site [chemical binding]; other site
879088003869	Switch I region; other site
879088003870	G2 box; other site
879088003871	G2 box; other site
879088003872	G3 box; other site
879088003873	G3 box; other site
879088003874	Switch II region; other site
879088003875	Switch II region; other site
879088003876	G5 box; other site
879088003877	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
879088003878	RNA/DNA hybrid binding site [nucleotide binding]; other site
879088003879	active site
879088003880	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
879088003881	DNA protecting protein DprA; Region: dprA; TIGR00732
879088003882	DNA topoisomerase I; Validated; Region: PRK05582
879088003883	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
879088003884	active site
879088003885	interdomain interaction site; other site
879088003886	putative metal-binding site [ion binding]; other site
879088003887	nucleotide binding site [chemical binding]; other site
879088003888	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
879088003889	domain I; other site
879088003890	DNA binding groove [nucleotide binding]
879088003891	phosphate binding site [ion binding]; other site
879088003892	domain II; other site
879088003893	domain III; other site
879088003894	nucleotide binding site [chemical binding]; other site
879088003895	catalytic site [active]
879088003896	domain IV; other site
879088003897	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
879088003898	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
879088003899	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
879088003900	Glucose inhibited division protein A; Region: GIDA; pfam01134
879088003901	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
879088003902	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
879088003903	active site
879088003904	DNA binding site [nucleotide binding]
879088003905	Int/Topo IB signature motif; other site
879088003906	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
879088003907	active site
879088003908	HslU subunit interaction site [polypeptide binding]; other site
879088003909	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
879088003910	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088003911	Walker A motif; other site
879088003912	ATP binding site [chemical binding]; other site
879088003913	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
879088003914	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
879088003915	transcriptional repressor CodY; Validated; Region: PRK04158
879088003916	CodY GAF-like domain; Region: CodY; pfam06018
879088003917	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
879088003918	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
879088003919	active site
879088003920	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
879088003921	active site
879088003922	catalytic residues [active]
879088003923	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
879088003924	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
879088003925	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
879088003926	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088003927	Mg2+ binding site [ion binding]; other site
879088003928	G-X-G motif; other site
879088003929	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
879088003930	anchoring element; other site
879088003931	dimer interface [polypeptide binding]; other site
879088003932	ATP binding site [chemical binding]; other site
879088003933	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
879088003934	active site
879088003935	putative metal-binding site [ion binding]; other site
879088003936	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
879088003937	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
879088003938	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
879088003939	CAP-like domain; other site
879088003940	active site
879088003941	primary dimer interface [polypeptide binding]; other site
879088003942	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
879088003943	S-ribosylhomocysteinase; Provisional; Region: PRK02260
879088003944	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
879088003945	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088003946	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
879088003947	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
879088003948	catalytic triad [active]
879088003949	catalytic triad [active]
879088003950	oxyanion hole [active]
879088003951	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
879088003952	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
879088003953	active site
879088003954	catalytic site [active]
879088003955	metal binding site [ion binding]; metal-binding site
879088003956	dimer interface [polypeptide binding]; other site
879088003957	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
879088003958	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
879088003959	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
879088003960	bacterial Hfq-like; Region: Hfq; cd01716
879088003961	hexamer interface [polypeptide binding]; other site
879088003962	Sm1 motif; other site
879088003963	RNA binding site [nucleotide binding]; other site
879088003964	Sm2 motif; other site
879088003965	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
879088003966	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
879088003967	HflX GTPase family; Region: HflX; cd01878
879088003968	G1 box; other site
879088003969	GTP/Mg2+ binding site [chemical binding]; other site
879088003970	Switch I region; other site
879088003971	G2 box; other site
879088003972	G3 box; other site
879088003973	Switch II region; other site
879088003974	G4 box; other site
879088003975	G5 box; other site
879088003976	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
879088003977	Aluminium resistance protein; Region: Alum_res; pfam06838
879088003978	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
879088003979	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
879088003980	DNA binding residues [nucleotide binding]
879088003981	putative dimer interface [polypeptide binding]; other site
879088003982	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
879088003983	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
879088003984	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
879088003985	arsenical pump membrane protein; Provisional; Region: PRK15445
879088003986	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
879088003987	transmembrane helices; other site
879088003988	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
879088003989	LexA repressor; Validated; Region: PRK00215
879088003990	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088003991	putative DNA binding site [nucleotide binding]; other site
879088003992	putative Zn2+ binding site [ion binding]; other site
879088003993	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
879088003994	Catalytic site [active]
879088003995	cell division suppressor protein YneA; Provisional; Region: PRK14125
879088003996	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
879088003997	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
879088003998	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
879088003999	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
879088004000	TPP-binding site [chemical binding]; other site
879088004001	dimer interface [polypeptide binding]; other site
879088004002	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
879088004003	PYR/PP interface [polypeptide binding]; other site
879088004004	dimer interface [polypeptide binding]; other site
879088004005	TPP binding site [chemical binding]; other site
879088004006	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088004007	hypothetical protein; Provisional; Region: PRK01844
879088004008	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
879088004009	Methyltransferase domain; Region: Methyltransf_31; pfam13847
879088004010	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088004011	S-adenosylmethionine binding site [chemical binding]; other site
879088004012	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
879088004013	ParB-like nuclease domain; Region: ParBc; pfam02195
879088004014	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
879088004015	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
879088004016	Active Sites [active]
879088004017	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
879088004018	DEAD-like helicases superfamily; Region: DEXDc; smart00487
879088004019	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
879088004020	putative nucleotide binding site [chemical binding]; other site
879088004021	uridine monophosphate binding site [chemical binding]; other site
879088004022	homohexameric interface [polypeptide binding]; other site
879088004023	ribosome recycling factor; Reviewed; Region: frr; PRK00083
879088004024	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
879088004025	hinge region; other site
879088004026	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
879088004027	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
879088004028	catalytic residue [active]
879088004029	putative FPP diphosphate  binding site; other site
879088004030	putative FPP binding hydrophobic cleft; other site
879088004031	dimer interface [polypeptide binding]; other site
879088004032	putative IPP diphosphate binding site; other site
879088004033	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
879088004034	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
879088004035	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
879088004036	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
879088004037	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
879088004038	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
879088004039	RIP metalloprotease RseP; Region: TIGR00054
879088004040	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
879088004041	active site
879088004042	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
879088004043	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
879088004044	protein binding site [polypeptide binding]; other site
879088004045	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
879088004046	putative substrate binding region [chemical binding]; other site
879088004047	prolyl-tRNA synthetase; Provisional; Region: PRK09194
879088004048	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
879088004049	dimer interface [polypeptide binding]; other site
879088004050	motif 1; other site
879088004051	active site
879088004052	motif 2; other site
879088004053	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
879088004054	putative deacylase active site [active]
879088004055	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
879088004056	active site
879088004057	motif 3; other site
879088004058	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
879088004059	anticodon binding site; other site
879088004060	DNA polymerase III PolC; Validated; Region: polC; PRK00448
879088004061	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
879088004062	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
879088004063	generic binding surface II; other site
879088004064	generic binding surface I; other site
879088004065	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
879088004066	active site
879088004067	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
879088004068	active site
879088004069	catalytic site [active]
879088004070	substrate binding site [chemical binding]; other site
879088004071	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
879088004072	ribosome maturation protein RimP; Reviewed; Region: PRK00092
879088004073	Sm and related proteins; Region: Sm_like; cl00259
879088004074	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
879088004075	putative oligomer interface [polypeptide binding]; other site
879088004076	putative RNA binding site [nucleotide binding]; other site
879088004077	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
879088004078	NusA N-terminal domain; Region: NusA_N; pfam08529
879088004079	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
879088004080	RNA binding site [nucleotide binding]; other site
879088004081	homodimer interface [polypeptide binding]; other site
879088004082	NusA-like KH domain; Region: KH_5; pfam13184
879088004083	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
879088004084	G-X-X-G motif; other site
879088004085	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
879088004086	putative RNA binding cleft [nucleotide binding]; other site
879088004087	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
879088004088	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
879088004089	translation initiation factor IF-2; Region: IF-2; TIGR00487
879088004090	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
879088004091	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
879088004092	G1 box; other site
879088004093	putative GEF interaction site [polypeptide binding]; other site
879088004094	GTP/Mg2+ binding site [chemical binding]; other site
879088004095	Switch I region; other site
879088004096	G2 box; other site
879088004097	G3 box; other site
879088004098	Switch II region; other site
879088004099	G4 box; other site
879088004100	G5 box; other site
879088004101	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
879088004102	Translation-initiation factor 2; Region: IF-2; pfam11987
879088004103	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
879088004104	Protein of unknown function (DUF503); Region: DUF503; cl00669
879088004105	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
879088004106	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
879088004107	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
879088004108	RNA binding site [nucleotide binding]; other site
879088004109	active site
879088004110	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
879088004111	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
879088004112	active site
879088004113	Riboflavin kinase; Region: Flavokinase; smart00904
879088004114	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
879088004115	16S/18S rRNA binding site [nucleotide binding]; other site
879088004116	S13e-L30e interaction site [polypeptide binding]; other site
879088004117	25S rRNA binding site [nucleotide binding]; other site
879088004118	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
879088004119	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
879088004120	RNase E interface [polypeptide binding]; other site
879088004121	trimer interface [polypeptide binding]; other site
879088004122	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
879088004123	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
879088004124	RNase E interface [polypeptide binding]; other site
879088004125	trimer interface [polypeptide binding]; other site
879088004126	active site
879088004127	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
879088004128	putative nucleic acid binding region [nucleotide binding]; other site
879088004129	G-X-X-G motif; other site
879088004130	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
879088004131	RNA binding site [nucleotide binding]; other site
879088004132	domain interface; other site
879088004133	GTPase RsgA; Reviewed; Region: PRK01889
879088004134	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
879088004135	RNA binding site [nucleotide binding]; other site
879088004136	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
879088004137	GTPase/Zn-binding domain interface [polypeptide binding]; other site
879088004138	GTP/Mg2+ binding site [chemical binding]; other site
879088004139	G4 box; other site
879088004140	G5 box; other site
879088004141	G1 box; other site
879088004142	Switch I region; other site
879088004143	G2 box; other site
879088004144	G3 box; other site
879088004145	Switch II region; other site
879088004146	YceG-like family; Region: YceG; pfam02618
879088004147	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
879088004148	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
879088004149	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
879088004150	Rhomboid family; Region: Rhomboid; pfam01694
879088004151	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088004152	TPR motif; other site
879088004153	TPR repeat; Region: TPR_11; pfam13414
879088004154	binding surface
879088004155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4483
879088004156	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
879088004157	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088004158	nucleotide binding site [chemical binding]; other site
879088004159	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
879088004160	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
879088004161	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
879088004162	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
879088004163	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
879088004164	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
879088004165	Type II/IV secretion system protein; Region: T2SE; pfam00437
879088004166	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
879088004167	Walker A motif; other site
879088004168	ATP binding site [chemical binding]; other site
879088004169	Walker B motif; other site
879088004170	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
879088004171	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
879088004172	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
879088004173	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
879088004174	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
879088004175	tetramer interface [polypeptide binding]; other site
879088004176	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088004177	catalytic residue [active]
879088004178	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
879088004179	tetramer interface [polypeptide binding]; other site
879088004180	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088004181	catalytic residue [active]
879088004182	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
879088004183	active site residue [active]
879088004184	Predicted metal-dependent enzyme [General function prediction only]; Region: COG3872
879088004185	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
879088004186	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
879088004187	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
879088004188	active site
879088004189	elongation factor P; Validated; Region: PRK00529
879088004190	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
879088004191	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
879088004192	RNA binding site [nucleotide binding]; other site
879088004193	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
879088004194	RNA binding site [nucleotide binding]; other site
879088004195	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
879088004196	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
879088004197	carboxyltransferase (CT) interaction site; other site
879088004198	biotinylation site [posttranslational modification]; other site
879088004199	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
879088004200	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
879088004201	ATP-grasp domain; Region: ATP-grasp_4; cl17255
879088004202	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
879088004203	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
879088004204	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
879088004205	putative RNA binding site [nucleotide binding]; other site
879088004206	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14170
879088004207	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
879088004208	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
879088004209	homodimer interface [polypeptide binding]; other site
879088004210	NADP binding site [chemical binding]; other site
879088004211	substrate binding site [chemical binding]; other site
879088004212	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
879088004213	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
879088004214	generic binding surface II; other site
879088004215	generic binding surface I; other site
879088004216	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14064
879088004217	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
879088004218	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
879088004219	substrate binding pocket [chemical binding]; other site
879088004220	chain length determination region; other site
879088004221	substrate-Mg2+ binding site; other site
879088004222	catalytic residues [active]
879088004223	aspartate-rich region 1; other site
879088004224	active site lid residues [active]
879088004225	aspartate-rich region 2; other site
879088004226	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
879088004227	DNA-binding site [nucleotide binding]; DNA binding site
879088004228	RNA-binding motif; other site
879088004229	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
879088004230	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
879088004231	TPP-binding site; other site
879088004232	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
879088004233	PYR/PP interface [polypeptide binding]; other site
879088004234	dimer interface [polypeptide binding]; other site
879088004235	TPP binding site [chemical binding]; other site
879088004236	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088004237	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
879088004238	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088004239	RNA binding surface [nucleotide binding]; other site
879088004240	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
879088004241	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
879088004242	arginine repressor; Provisional; Region: PRK04280
879088004243	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
879088004244	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
879088004245	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
879088004246	Walker A/P-loop; other site
879088004247	ATP binding site [chemical binding]; other site
879088004248	Q-loop/lid; other site
879088004249	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
879088004250	ABC transporter signature motif; other site
879088004251	Walker B; other site
879088004252	D-loop; other site
879088004253	H-loop/switch region; other site
879088004254	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
879088004255	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088004256	nucleotide binding site [chemical binding]; other site
879088004257	Acetokinase family; Region: Acetate_kinase; cl17229
879088004258	dihydrolipoamide dehydrogenase; Validated; Region: PRK05976
879088004259	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088004260	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
879088004261	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
879088004262	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
879088004263	tetramer interface [polypeptide binding]; other site
879088004264	TPP-binding site [chemical binding]; other site
879088004265	heterodimer interface [polypeptide binding]; other site
879088004266	phosphorylation loop region [posttranslational modification]
879088004267	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
879088004268	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
879088004269	alpha subunit interface [polypeptide binding]; other site
879088004270	TPP binding site [chemical binding]; other site
879088004271	heterodimer interface [polypeptide binding]; other site
879088004272	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
879088004273	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
879088004274	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
879088004275	E3 interaction surface; other site
879088004276	lipoyl attachment site [posttranslational modification]; other site
879088004277	e3 binding domain; Region: E3_binding; pfam02817
879088004278	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
879088004279	peptidase T-like protein; Region: PepT-like; TIGR01883
879088004280	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
879088004281	metal binding site [ion binding]; metal-binding site
879088004282	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
879088004283	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
879088004284	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
879088004285	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088004286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088004287	active site
879088004288	phosphorylation site [posttranslational modification]
879088004289	intermolecular recognition site; other site
879088004290	dimerization interface [polypeptide binding]; other site
879088004291	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088004292	DNA binding site [nucleotide binding]
879088004293	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
879088004294	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088004295	dimerization interface [polypeptide binding]; other site
879088004296	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088004297	dimer interface [polypeptide binding]; other site
879088004298	phosphorylation site [posttranslational modification]
879088004299	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088004300	ATP binding site [chemical binding]; other site
879088004301	Mg2+ binding site [ion binding]; other site
879088004302	G-X-G motif; other site
879088004303	OxaA-like protein precursor; Validated; Region: PRK01622
879088004304	acylphosphatase; Provisional; Region: PRK14443
879088004305	Protein of unknown function (DUF1033); Region: DUF1033; cl11549
879088004306	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
879088004307	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
879088004308	homotetramer interface [polypeptide binding]; other site
879088004309	FMN binding site [chemical binding]; other site
879088004310	homodimer contacts [polypeptide binding]; other site
879088004311	putative active site [active]
879088004312	putative substrate binding site [chemical binding]; other site
879088004313	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
879088004314	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
879088004315	active site residue [active]
879088004316	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
879088004317	Uncharacterized conserved protein [Function unknown]; Region: COG1284
879088004318	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088004319	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088004320	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
879088004321	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
879088004322	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
879088004323	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
879088004324	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06928
879088004325	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
879088004326	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
879088004327	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
879088004328	ligand binding site [chemical binding]; other site
879088004329	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
879088004330	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
879088004331	Walker A/P-loop; other site
879088004332	ATP binding site [chemical binding]; other site
879088004333	Q-loop/lid; other site
879088004334	ABC transporter signature motif; other site
879088004335	Walker B; other site
879088004336	D-loop; other site
879088004337	H-loop/switch region; other site
879088004338	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
879088004339	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
879088004340	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
879088004341	TM-ABC transporter signature motif; other site
879088004342	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
879088004343	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
879088004344	TM-ABC transporter signature motif; other site
879088004345	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
879088004346	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
879088004347	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
879088004348	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
879088004349	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
879088004350	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
879088004351	classical (c) SDRs; Region: SDR_c; cd05233
879088004352	NAD(P) binding site [chemical binding]; other site
879088004353	active site
879088004354	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
879088004355	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088004356	non-specific DNA binding site [nucleotide binding]; other site
879088004357	salt bridge; other site
879088004358	sequence-specific DNA binding site [nucleotide binding]; other site
879088004359	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
879088004360	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
879088004361	competence damage-inducible protein A; Provisional; Region: PRK00549
879088004362	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
879088004363	putative MPT binding site; other site
879088004364	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
879088004365	recombinase A; Provisional; Region: recA; PRK09354
879088004366	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
879088004367	hexamer interface [polypeptide binding]; other site
879088004368	Walker A motif; other site
879088004369	ATP binding site [chemical binding]; other site
879088004370	Walker B motif; other site
879088004371	phosphodiesterase; Provisional; Region: PRK12704
879088004372	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088004373	Zn2+ binding site [ion binding]; other site
879088004374	Mg2+ binding site [ion binding]; other site
879088004375	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
879088004376	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088004377	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
879088004378	Coenzyme A binding pocket [chemical binding]; other site
879088004379	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
879088004380	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
879088004381	putative active site [active]
879088004382	metal binding site [ion binding]; metal-binding site
879088004383	homodimer binding site [polypeptide binding]; other site
879088004384	Predicted membrane protein [Function unknown]; Region: COG4550
879088004385	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
879088004386	MutS domain I; Region: MutS_I; pfam01624
879088004387	MutS domain II; Region: MutS_II; pfam05188
879088004388	MutS domain III; Region: MutS_III; pfam05192
879088004389	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
879088004390	Walker A/P-loop; other site
879088004391	ATP binding site [chemical binding]; other site
879088004392	Q-loop/lid; other site
879088004393	ABC transporter signature motif; other site
879088004394	Walker B; other site
879088004395	D-loop; other site
879088004396	H-loop/switch region; other site
879088004397	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
879088004398	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088004399	ATP binding site [chemical binding]; other site
879088004400	Mg2+ binding site [ion binding]; other site
879088004401	G-X-G motif; other site
879088004402	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
879088004403	ATP binding site [chemical binding]; other site
879088004404	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
879088004405	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
879088004406	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
879088004407	Pyruvate formate lyase 1; Region: PFL1; cd01678
879088004408	coenzyme A binding site [chemical binding]; other site
879088004409	active site
879088004410	catalytic residues [active]
879088004411	glycine loop; other site
879088004412	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
879088004413	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
879088004414	FeS/SAM binding site; other site
879088004415	Predicted transcriptional regulators [Transcription]; Region: COG1695
879088004416	Transcriptional regulator PadR-like family; Region: PadR; cl17335
879088004417	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
879088004418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088004419	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088004420	putative substrate translocation pore; other site
879088004421	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088004422	non-specific DNA binding site [nucleotide binding]; other site
879088004423	salt bridge; other site
879088004424	sequence-specific DNA binding site [nucleotide binding]; other site
879088004425	topology modulation protein; Reviewed; Region: PRK08118
879088004426	AAA domain; Region: AAA_17; pfam13207
879088004427	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088004428	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088004429	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088004430	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088004431	putative acyltransferase; Provisional; Region: PRK05790
879088004432	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
879088004433	dimer interface [polypeptide binding]; other site
879088004434	active site
879088004435	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
879088004436	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
879088004437	dimer interface [polypeptide binding]; other site
879088004438	active site
879088004439	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
879088004440	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
879088004441	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088004442	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
879088004443	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
879088004444	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
879088004445	Domain of unknown function DUF20; Region: UPF0118; pfam01594
879088004446	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
879088004447	FAD binding domain; Region: FAD_binding_4; pfam01565
879088004448	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
879088004449	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
879088004450	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
879088004451	Walker A/P-loop; other site
879088004452	ATP binding site [chemical binding]; other site
879088004453	Q-loop/lid; other site
879088004454	ABC transporter signature motif; other site
879088004455	Walker B; other site
879088004456	D-loop; other site
879088004457	H-loop/switch region; other site
879088004458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088004459	dimer interface [polypeptide binding]; other site
879088004460	conserved gate region; other site
879088004461	ABC-ATPase subunit interface; other site
879088004462	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
879088004463	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
879088004464	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
879088004465	manganese transport protein MntH; Reviewed; Region: PRK00701
879088004466	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
879088004467	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088004468	dimer interface [polypeptide binding]; other site
879088004469	conserved gate region; other site
879088004470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
879088004471	ABC-ATPase subunit interface; other site
879088004472	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
879088004473	LysR substrate binding domain; Region: LysR_substrate; pfam03466
879088004474	dimerization interface [polypeptide binding]; other site
879088004475	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088004476	dimer interface [polypeptide binding]; other site
879088004477	conserved gate region; other site
879088004478	putative PBP binding loops; other site
879088004479	ABC-ATPase subunit interface; other site
879088004480	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
879088004481	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
879088004482	Walker A/P-loop; other site
879088004483	ATP binding site [chemical binding]; other site
879088004484	Q-loop/lid; other site
879088004485	ABC transporter signature motif; other site
879088004486	Walker B; other site
879088004487	D-loop; other site
879088004488	H-loop/switch region; other site
879088004489	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
879088004490	Predicted membrane protein [Function unknown]; Region: COG3859
879088004491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
879088004492	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
879088004493	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088004494	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088004495	ABC transporter; Region: ABC_tran_2; pfam12848
879088004496	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088004497	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
879088004498	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088004499	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088004500	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
879088004501	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
879088004502	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088004503	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
879088004504	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
879088004505	dihydrodipicolinate synthase; Region: dapA; TIGR00674
879088004506	dimer interface [polypeptide binding]; other site
879088004507	active site
879088004508	catalytic residue [active]
879088004509	aspartate kinase I; Reviewed; Region: PRK08210
879088004510	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
879088004511	nucleotide binding site [chemical binding]; other site
879088004512	substrate binding site [chemical binding]; other site
879088004513	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_1; cd04914
879088004514	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_2; cd04937
879088004515	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
879088004516	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
879088004517	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
879088004518	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
879088004519	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
879088004520	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
879088004521	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
879088004522	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
879088004523	Protein of unknown function (DUF1189); Region: DUF1189; pfam06691
879088004524	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
879088004525	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
879088004526	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
879088004527	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
879088004528	Predicted membrane protein [Function unknown]; Region: COG4392
879088004529	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
879088004530	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
879088004531	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
879088004532	metal binding site 2 [ion binding]; metal-binding site
879088004533	putative DNA binding helix; other site
879088004534	metal binding site 1 [ion binding]; metal-binding site
879088004535	dimer interface [polypeptide binding]; other site
879088004536	structural Zn2+ binding site [ion binding]; other site
879088004537	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
879088004538	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088004539	ABC-ATPase subunit  interface; other site
879088004540	dimer interface [polypeptide binding]; other site
879088004541	putative PBP binding regions; other site
879088004542	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
879088004543	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
879088004544	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
879088004545	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
879088004546	DHHA2 domain; Region: DHHA2; pfam02833
879088004547	endonuclease IV; Provisional; Region: PRK01060
879088004548	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
879088004549	AP (apurinic/apyrimidinic) site pocket; other site
879088004550	DNA interaction; other site
879088004551	Metal-binding active site; metal-binding site
879088004552	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
879088004553	DEAD-like helicases superfamily; Region: DEXDc; smart00487
879088004554	ATP binding site [chemical binding]; other site
879088004555	Mg++ binding site [ion binding]; other site
879088004556	motif III; other site
879088004557	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088004558	nucleotide binding region [chemical binding]; other site
879088004559	ATP-binding site [chemical binding]; other site
879088004560	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
879088004561	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
879088004562	Uncharacterized conserved protein [Function unknown]; Region: COG0327
879088004563	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
879088004564	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
879088004565	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
879088004566	Uncharacterized conserved protein [Function unknown]; Region: COG0327
879088004567	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
879088004568	Family of unknown function (DUF633); Region: DUF633; pfam04816
879088004569	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
879088004570	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
879088004571	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
879088004572	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
879088004573	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
879088004574	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
879088004575	DNA binding residues [nucleotide binding]
879088004576	DNA primase; Validated; Region: dnaG; PRK05667
879088004577	CHC2 zinc finger; Region: zf-CHC2; pfam01807
879088004578	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
879088004579	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
879088004580	active site
879088004581	metal binding site [ion binding]; metal-binding site
879088004582	interdomain interaction site; other site
879088004583	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
879088004584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1671
879088004585	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
879088004586	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
879088004587	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
879088004588	DALR anticodon binding domain; Region: DALR_1; pfam05746
879088004589	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
879088004590	dimer interface [polypeptide binding]; other site
879088004591	motif 1; other site
879088004592	active site
879088004593	motif 2; other site
879088004594	motif 3; other site
879088004595	DNA repair protein RecO; Region: reco; TIGR00613
879088004596	Recombination protein O N terminal; Region: RecO_N; pfam11967
879088004597	Recombination protein O C terminal; Region: RecO_C; pfam02565
879088004598	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
879088004599	GTPase Era; Reviewed; Region: era; PRK00089
879088004600	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
879088004601	G1 box; other site
879088004602	GTP/Mg2+ binding site [chemical binding]; other site
879088004603	Switch I region; other site
879088004604	G2 box; other site
879088004605	Switch II region; other site
879088004606	G3 box; other site
879088004607	G4 box; other site
879088004608	G5 box; other site
879088004609	KH domain; Region: KH_2; pfam07650
879088004610	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
879088004611	active site
879088004612	catalytic motif [active]
879088004613	Zn binding site [ion binding]; other site
879088004614	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
879088004615	metal-binding heat shock protein; Provisional; Region: PRK00016
879088004616	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
879088004617	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
879088004618	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088004619	Zn2+ binding site [ion binding]; other site
879088004620	Mg2+ binding site [ion binding]; other site
879088004621	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
879088004622	PhoH-like protein; Region: PhoH; pfam02562
879088004623	Yqey-like protein; Region: YqeY; pfam09424
879088004624	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
879088004625	RNA methyltransferase, RsmE family; Region: TIGR00046
879088004626	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
879088004627	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
879088004628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088004629	S-adenosylmethionine binding site [chemical binding]; other site
879088004630	chaperone protein DnaJ; Provisional; Region: PRK14280
879088004631	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
879088004632	HSP70 interaction site [polypeptide binding]; other site
879088004633	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
879088004634	substrate binding site [polypeptide binding]; other site
879088004635	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
879088004636	Zn binding sites [ion binding]; other site
879088004637	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
879088004638	dimer interface [polypeptide binding]; other site
879088004639	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
879088004640	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
879088004641	nucleotide binding site [chemical binding]; other site
879088004642	NEF interaction site [polypeptide binding]; other site
879088004643	SBD interface [polypeptide binding]; other site
879088004644	heat shock protein GrpE; Provisional; Region: PRK14140
879088004645	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
879088004646	dimer interface [polypeptide binding]; other site
879088004647	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
879088004648	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
879088004649	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
879088004650	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
879088004651	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
879088004652	FeS/SAM binding site; other site
879088004653	HemN C-terminal domain; Region: HemN_C; pfam06969
879088004654	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
879088004655	aldehyde reductase, extended (e) SDRs; Region: AR_SDR_e; cd05227
879088004656	NADP binding site [chemical binding]; other site
879088004657	putative substrate binding site [chemical binding]; other site
879088004658	active site
879088004659	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088004660	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088004661	DNA binding residues [nucleotide binding]
879088004662	putative dimer interface [polypeptide binding]; other site
879088004663	GTP-binding protein LepA; Provisional; Region: PRK05433
879088004664	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
879088004665	G1 box; other site
879088004666	putative GEF interaction site [polypeptide binding]; other site
879088004667	GTP/Mg2+ binding site [chemical binding]; other site
879088004668	Switch I region; other site
879088004669	G2 box; other site
879088004670	G3 box; other site
879088004671	Switch II region; other site
879088004672	G4 box; other site
879088004673	G5 box; other site
879088004674	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
879088004675	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
879088004676	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
879088004677	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
879088004678	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
879088004679	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
879088004680	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
879088004681	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
879088004682	Competence protein; Region: Competence; pfam03772
879088004683	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088004684	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
879088004685	catalytic motif [active]
879088004686	Zn binding site [ion binding]; other site
879088004687	SLBB domain; Region: SLBB; pfam10531
879088004688	comEA protein; Region: comE; TIGR01259
879088004689	Helix-hairpin-helix motif; Region: HHH; pfam00633
879088004690	Methyltransferase domain; Region: Methyltransf_23; pfam13489
879088004691	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088004692	S-adenosylmethionine binding site [chemical binding]; other site
879088004693	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
879088004694	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088004695	Zn2+ binding site [ion binding]; other site
879088004696	Mg2+ binding site [ion binding]; other site
879088004697	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
879088004698	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
879088004699	active site
879088004700	(T/H)XGH motif; other site
879088004701	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
879088004702	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
879088004703	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
879088004704	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
879088004705	shikimate binding site; other site
879088004706	NAD(P) binding site [chemical binding]; other site
879088004707	GTPase YqeH; Provisional; Region: PRK13796
879088004708	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
879088004709	GTP/Mg2+ binding site [chemical binding]; other site
879088004710	G4 box; other site
879088004711	G5 box; other site
879088004712	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
879088004713	G1 box; other site
879088004714	G1 box; other site
879088004715	GTP/Mg2+ binding site [chemical binding]; other site
879088004716	G2 box; other site
879088004717	Switch I region; other site
879088004718	G2 box; other site
879088004719	Switch I region; other site
879088004720	G3 box; other site
879088004721	G3 box; other site
879088004722	Switch II region; other site
879088004723	Switch II region; other site
879088004724	G4 box; other site
879088004725	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
879088004726	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088004727	motif II; other site
879088004728	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
879088004729	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
879088004730	active site
879088004731	Zn binding site [ion binding]; other site
879088004732	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
879088004733	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
879088004734	Protein of unknown function (DUF1510); Region: DUF1510; pfam07423
879088004735	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
879088004736	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
879088004737	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
879088004738	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
879088004739	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
879088004740	Sugar specificity; other site
879088004741	Pyrimidine base specificity; other site
879088004742	ATP-binding site [chemical binding]; other site
879088004743	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
879088004744	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088004745	S-adenosylmethionine binding site [chemical binding]; other site
879088004746	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
879088004747	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
879088004748	dimerization interface [polypeptide binding]; other site
879088004749	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
879088004750	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
879088004751	hypothetical protein; Provisional; Region: PRK13678
879088004752	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
879088004753	hypothetical protein; Provisional; Region: PRK05473
879088004754	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
879088004755	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
879088004756	motif 1; other site
879088004757	active site
879088004758	motif 2; other site
879088004759	motif 3; other site
879088004760	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
879088004761	DHHA1 domain; Region: DHHA1; pfam02272
879088004762	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088004763	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088004764	Walker A/P-loop; other site
879088004765	ATP binding site [chemical binding]; other site
879088004766	Q-loop/lid; other site
879088004767	ABC transporter signature motif; other site
879088004768	Walker B; other site
879088004769	D-loop; other site
879088004770	H-loop/switch region; other site
879088004771	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088004772	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088004773	FtsX-like permease family; Region: FtsX; pfam02687
879088004774	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088004775	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088004776	active site
879088004777	phosphorylation site [posttranslational modification]
879088004778	intermolecular recognition site; other site
879088004779	dimerization interface [polypeptide binding]; other site
879088004780	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088004781	DNA binding site [nucleotide binding]
879088004782	sensor kinase CusS; Provisional; Region: PRK09835
879088004783	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088004784	dimerization interface [polypeptide binding]; other site
879088004785	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088004786	dimer interface [polypeptide binding]; other site
879088004787	phosphorylation site [posttranslational modification]
879088004788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088004789	ATP binding site [chemical binding]; other site
879088004790	Mg2+ binding site [ion binding]; other site
879088004791	G-X-G motif; other site
879088004792	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
879088004793	AAA domain; Region: AAA_30; pfam13604
879088004794	Family description; Region: UvrD_C_2; pfam13538
879088004795	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088004796	binding surface
879088004797	TPR motif; other site
879088004798	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
879088004799	TPR repeat; Region: TPR_11; pfam13414
879088004800	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088004801	binding surface
879088004802	TPR motif; other site
879088004803	TPR repeat; Region: TPR_11; pfam13414
879088004804	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
879088004805	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
879088004806	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
879088004807	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
879088004808	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
879088004809	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088004810	catalytic residue [active]
879088004811	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
879088004812	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088004813	Walker A motif; other site
879088004814	ATP binding site [chemical binding]; other site
879088004815	Walker B motif; other site
879088004816	arginine finger; other site
879088004817	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
879088004818	Predicted transcriptional regulator [Transcription]; Region: COG1959
879088004819	Transcriptional regulator; Region: Rrf2; pfam02082
879088004820	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
879088004821	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
879088004822	Nitrogen regulatory protein P-II; Region: P-II; smart00938
879088004823	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
879088004824	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
879088004825	dimer interface [polypeptide binding]; other site
879088004826	anticodon binding site; other site
879088004827	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
879088004828	homodimer interface [polypeptide binding]; other site
879088004829	motif 1; other site
879088004830	active site
879088004831	motif 2; other site
879088004832	GAD domain; Region: GAD; pfam02938
879088004833	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
879088004834	motif 3; other site
879088004835	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
879088004836	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
879088004837	dimer interface [polypeptide binding]; other site
879088004838	motif 1; other site
879088004839	active site
879088004840	motif 2; other site
879088004841	motif 3; other site
879088004842	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
879088004843	anticodon binding site; other site
879088004844	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
879088004845	Bacterial SH3 domain; Region: SH3_3; pfam08239
879088004846	Bacterial SH3 domain; Region: SH3_3; pfam08239
879088004847	Bacterial SH3 domain homologues; Region: SH3b; smart00287
879088004848	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
879088004849	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
879088004850	active site
879088004851	metal binding site [ion binding]; metal-binding site
879088004852	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
879088004853	putative active site [active]
879088004854	dimerization interface [polypeptide binding]; other site
879088004855	putative tRNAtyr binding site [nucleotide binding]; other site
879088004856	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
879088004857	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088004858	Zn2+ binding site [ion binding]; other site
879088004859	Mg2+ binding site [ion binding]; other site
879088004860	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
879088004861	synthetase active site [active]
879088004862	NTP binding site [chemical binding]; other site
879088004863	metal binding site [ion binding]; metal-binding site
879088004864	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
879088004865	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
879088004866	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088004867	active site
879088004868	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
879088004869	DHH family; Region: DHH; pfam01368
879088004870	DHHA1 domain; Region: DHHA1; pfam02272
879088004871	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4199
879088004872	Uncharacterized integral membrane protein [Function unknown]; Region: COG5416
879088004873	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
879088004874	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
879088004875	Protein export membrane protein; Region: SecD_SecF; cl14618
879088004876	Protein export membrane protein; Region: SecD_SecF; pfam02355
879088004877	Post-transcriptional regulator; Region: Post_transc_reg; pfam13797
879088004878	Preprotein translocase subunit; Region: YajC; pfam02699
879088004879	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
879088004880	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
879088004881	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
879088004882	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
879088004883	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
879088004884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088004885	Walker A motif; other site
879088004886	ATP binding site [chemical binding]; other site
879088004887	Walker B motif; other site
879088004888	arginine finger; other site
879088004889	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
879088004890	Holliday junction resolvasome, DNA-binding subunit [DNA replication, recombination, and repair]; Region: RuvA; COG0632
879088004891	RuvA N terminal domain; Region: RuvA_N; pfam01330
879088004892	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
879088004893	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
879088004894	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088004895	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
879088004896	NAD binding site [chemical binding]; other site
879088004897	dimer interface [polypeptide binding]; other site
879088004898	substrate binding site [chemical binding]; other site
879088004899	hypothetical protein; Validated; Region: PRK00110
879088004900	prephenate dehydratase; Provisional; Region: PRK11898
879088004901	Prephenate dehydratase; Region: PDT; pfam00800
879088004902	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
879088004903	putative L-Phe binding site [chemical binding]; other site
879088004904	GTPase CgtA; Reviewed; Region: obgE; PRK12297
879088004905	GTP1/OBG; Region: GTP1_OBG; pfam01018
879088004906	Obg GTPase; Region: Obg; cd01898
879088004907	G1 box; other site
879088004908	GTP/Mg2+ binding site [chemical binding]; other site
879088004909	Switch I region; other site
879088004910	G2 box; other site
879088004911	G3 box; other site
879088004912	Switch II region; other site
879088004913	G4 box; other site
879088004914	G5 box; other site
879088004915	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
879088004916	glycerol kinase; Provisional; Region: glpK; PRK00047
879088004917	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
879088004918	N- and C-terminal domain interface [polypeptide binding]; other site
879088004919	active site
879088004920	MgATP binding site [chemical binding]; other site
879088004921	catalytic site [active]
879088004922	metal binding site [ion binding]; metal-binding site
879088004923	glycerol binding site [chemical binding]; other site
879088004924	homotetramer interface [polypeptide binding]; other site
879088004925	homodimer interface [polypeptide binding]; other site
879088004926	FBP binding site [chemical binding]; other site
879088004927	protein IIAGlc interface [polypeptide binding]; other site
879088004928	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
879088004929	amphipathic channel; other site
879088004930	Asn-Pro-Ala signature motifs; other site
879088004931	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
879088004932	Predicted ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG2868
879088004933	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
879088004934	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
879088004935	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
879088004936	homodimer interface [polypeptide binding]; other site
879088004937	oligonucleotide binding site [chemical binding]; other site
879088004938	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
879088004939	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
879088004940	Switch I; other site
879088004941	Switch II; other site
879088004942	septum formation inhibitor; Reviewed; Region: minC; PRK00513
879088004943	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
879088004944	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891
879088004945	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
879088004946	Protein of unknown function (DUF972); Region: DUF972; pfam06156
879088004947	rod shape-determining protein MreC; Region: MreC; pfam04085
879088004948	rod shape-determining protein MreB; Provisional; Region: PRK13927
879088004949	MreB and similar proteins; Region: MreB_like; cd10225
879088004950	nucleotide binding site [chemical binding]; other site
879088004951	Mg binding site [ion binding]; other site
879088004952	putative protofilament interaction site [polypeptide binding]; other site
879088004953	RodZ interaction site [polypeptide binding]; other site
879088004954	hypothetical protein; Reviewed; Region: PRK00024
879088004955	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
879088004956	MPN+ (JAMM) motif; other site
879088004957	Zinc-binding site [ion binding]; other site
879088004958	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
879088004959	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
879088004960	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
879088004961	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
879088004962	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
879088004963	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
879088004964	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
879088004965	active site
879088004966	HIGH motif; other site
879088004967	nucleotide binding site [chemical binding]; other site
879088004968	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
879088004969	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
879088004970	active site
879088004971	KMSKS motif; other site
879088004972	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
879088004973	tRNA binding surface [nucleotide binding]; other site
879088004974	anticodon binding site; other site
879088004975	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
879088004976	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
879088004977	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
879088004978	inhibitor-cofactor binding pocket; inhibition site
879088004979	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088004980	catalytic residue [active]
879088004981	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
879088004982	dimer interface [polypeptide binding]; other site
879088004983	active site
879088004984	Schiff base residues; other site
879088004985	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
879088004986	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
879088004987	active site
879088004988	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
879088004989	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
879088004990	domain interfaces; other site
879088004991	active site
879088004992	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
879088004993	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
879088004994	tRNA; other site
879088004995	putative tRNA binding site [nucleotide binding]; other site
879088004996	putative NADP binding site [chemical binding]; other site
879088004997	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
879088004998	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
879088004999	G1 box; other site
879088005000	GTP/Mg2+ binding site [chemical binding]; other site
879088005001	Switch I region; other site
879088005002	G2 box; other site
879088005003	G3 box; other site
879088005004	Switch II region; other site
879088005005	G4 box; other site
879088005006	G5 box; other site
879088005007	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
879088005008	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
879088005009	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
879088005010	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
879088005011	active site
879088005012	dimer interface [polypeptide binding]; other site
879088005013	motif 1; other site
879088005014	motif 2; other site
879088005015	motif 3; other site
879088005016	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
879088005017	anticodon binding site; other site
879088005018	primosomal protein DnaI; Reviewed; Region: PRK08939
879088005019	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
879088005020	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
879088005021	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
879088005022	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
879088005023	ATP cone domain; Region: ATP-cone; pfam03477
879088005024	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
879088005025	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
879088005026	CoA-binding site [chemical binding]; other site
879088005027	ATP-binding [chemical binding]; other site
879088005028	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
879088005029	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
879088005030	DNA binding site [nucleotide binding]
879088005031	catalytic residue [active]
879088005032	H2TH interface [polypeptide binding]; other site
879088005033	putative catalytic residues [active]
879088005034	turnover-facilitating residue; other site
879088005035	intercalation triad [nucleotide binding]; other site
879088005036	8OG recognition residue [nucleotide binding]; other site
879088005037	putative reading head residues; other site
879088005038	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
879088005039	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
879088005040	DNA polymerase I; Provisional; Region: PRK05755
879088005041	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
879088005042	active site
879088005043	metal binding site 1 [ion binding]; metal-binding site
879088005044	putative 5' ssDNA interaction site; other site
879088005045	metal binding site 3; metal-binding site
879088005046	metal binding site 2 [ion binding]; metal-binding site
879088005047	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
879088005048	putative DNA binding site [nucleotide binding]; other site
879088005049	putative metal binding site [ion binding]; other site
879088005050	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
879088005051	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
879088005052	active site
879088005053	DNA binding site [nucleotide binding]
879088005054	catalytic site [active]
879088005055	isocitrate dehydrogenase; Reviewed; Region: PRK07006
879088005056	isocitrate dehydrogenase; Validated; Region: PRK07362
879088005057	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
879088005058	dimer interface [polypeptide binding]; other site
879088005059	Citrate synthase; Region: Citrate_synt; pfam00285
879088005060	active site
879088005061	citrylCoA binding site [chemical binding]; other site
879088005062	oxalacetate/citrate binding site [chemical binding]; other site
879088005063	coenzyme A binding site [chemical binding]; other site
879088005064	catalytic triad [active]
879088005065	Protein of unknown function (DUF441); Region: DUF441; pfam04284
879088005066	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
879088005067	pyruvate kinase; Provisional; Region: PRK06354
879088005068	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
879088005069	domain interfaces; other site
879088005070	active site
879088005071	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
879088005072	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
879088005073	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
879088005074	active site
879088005075	ADP/pyrophosphate binding site [chemical binding]; other site
879088005076	dimerization interface [polypeptide binding]; other site
879088005077	allosteric effector site; other site
879088005078	fructose-1,6-bisphosphate binding site; other site
879088005079	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
879088005080	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
879088005081	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
879088005082	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
879088005083	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
879088005084	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
879088005085	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
879088005086	active site
879088005087	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
879088005088	generic binding surface I; other site
879088005089	generic binding surface II; other site
879088005090	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
879088005091	DHH family; Region: DHH; pfam01368
879088005092	DHHA1 domain; Region: DHHA1; pfam02272
879088005093	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
879088005094	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
879088005095	DNA-binding site [nucleotide binding]; DNA binding site
879088005096	DRTGG domain; Region: DRTGG; pfam07085
879088005097	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
879088005098	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
879088005099	active site 2 [active]
879088005100	active site 1 [active]
879088005101	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
879088005102	metal-dependent hydrolase; Provisional; Region: PRK00685
879088005103	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
879088005104	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
879088005105	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
879088005106	active site
879088005107	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
879088005108	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
879088005109	hexamer interface [polypeptide binding]; other site
879088005110	ligand binding site [chemical binding]; other site
879088005111	putative active site [active]
879088005112	NAD(P) binding site [chemical binding]; other site
879088005113	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
879088005114	Ligand Binding Site [chemical binding]; other site
879088005115	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
879088005116	propionate/acetate kinase; Provisional; Region: PRK12379
879088005117	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
879088005118	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005119	S-adenosylmethionine binding site [chemical binding]; other site
879088005120	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
879088005121	dimer interface [polypeptide binding]; other site
879088005122	catalytic triad [active]
879088005123	peroxidatic and resolving cysteines [active]
879088005124	RDD family; Region: RDD; pfam06271
879088005125	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
879088005126	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
879088005127	tandem repeat interface [polypeptide binding]; other site
879088005128	oligomer interface [polypeptide binding]; other site
879088005129	active site residues [active]
879088005130	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03501
879088005131	ATP-NAD kinase; Region: NAD_kinase; pfam01513
879088005132	ornithine carbamoyltransferase; Provisional; Region: PRK00779
879088005133	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
879088005134	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
879088005135	acetylornithine aminotransferase; Provisional; Region: argD; PRK02936
879088005136	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
879088005137	inhibitor-cofactor binding pocket; inhibition site
879088005138	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005139	catalytic residue [active]
879088005140	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
879088005141	nucleotide binding site [chemical binding]; other site
879088005142	N-acetyl-L-glutamate binding site [chemical binding]; other site
879088005143	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
879088005144	heterotetramer interface [polypeptide binding]; other site
879088005145	active site pocket [active]
879088005146	cleavage site
879088005147	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
879088005148	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
879088005149	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
879088005150	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
879088005151	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
879088005152	Ligand Binding Site [chemical binding]; other site
879088005153	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
879088005154	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
879088005155	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088005156	catalytic residue [active]
879088005157	Negative regulator of septation ring formation [Cell division and chromosome partitioning]; Region: EzrA; COG4477
879088005158	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
879088005159	GAF domain; Region: GAF_2; pfam13185
879088005160	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
879088005161	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
879088005162	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088005163	RNA binding surface [nucleotide binding]; other site
879088005164	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
879088005165	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
879088005166	active site
879088005167	HIGH motif; other site
879088005168	dimer interface [polypeptide binding]; other site
879088005169	KMSKS motif; other site
879088005170	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088005171	RNA binding surface [nucleotide binding]; other site
879088005172	catabolite control protein A; Region: ccpA; TIGR01481
879088005173	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088005174	DNA binding site [nucleotide binding]
879088005175	domain linker motif; other site
879088005176	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
879088005177	dimerization interface [polypeptide binding]; other site
879088005178	effector binding site; other site
879088005179	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595
879088005180	Chorismate mutase type II; Region: CM_2; cl00693
879088005181	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
879088005182	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
879088005183	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
879088005184	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
879088005185	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
879088005186	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
879088005187	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
879088005188	dimer interface [polypeptide binding]; other site
879088005189	decamer (pentamer of dimers) interface [polypeptide binding]; other site
879088005190	catalytic triad [active]
879088005191	peroxidatic and resolving cysteines [active]
879088005192	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
879088005193	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
879088005194	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
879088005195	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
879088005196	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
879088005197	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
879088005198	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
879088005199	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
879088005200	putative tRNA-binding site [nucleotide binding]; other site
879088005201	hypothetical protein; Provisional; Region: PRK13668
879088005202	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088005203	catalytic residues [active]
879088005204	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
879088005205	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
879088005206	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
879088005207	oligomer interface [polypeptide binding]; other site
879088005208	active site
879088005209	metal binding site [ion binding]; metal-binding site
879088005210	Predicted small secreted protein [Function unknown]; Region: COG5584
879088005211	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1937
879088005212	putative homodimer interface [polypeptide binding]; other site
879088005213	putative homotetramer interface [polypeptide binding]; other site
879088005214	putative allosteric switch controlling residues; other site
879088005215	putative metal binding site [ion binding]; other site
879088005216	putative homodimer-homodimer interface [polypeptide binding]; other site
879088005217	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088005218	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005219	S-adenosylmethionine binding site [chemical binding]; other site
879088005220	Phosphotransferase enzyme family; Region: APH; pfam01636
879088005221	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
879088005222	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
879088005223	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088005224	putative substrate translocation pore; other site
879088005225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088005226	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088005227	MarR family; Region: MarR; pfam01047
879088005228	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
879088005229	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
879088005230	homodimer interface [polypeptide binding]; other site
879088005231	substrate-cofactor binding pocket; other site
879088005232	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005233	catalytic residue [active]
879088005234	dipeptidase PepV; Reviewed; Region: PRK07318
879088005235	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
879088005236	active site
879088005237	metal binding site [ion binding]; metal-binding site
879088005238	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_39; cd04699
879088005239	nudix motif; other site
879088005240	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
879088005241	putative substrate binding site [chemical binding]; other site
879088005242	putative ATP binding site [chemical binding]; other site
879088005243	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
879088005244	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
879088005245	active site
879088005246	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
879088005247	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
879088005248	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
879088005249	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
879088005250	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
879088005251	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
879088005252	substrate binding site [chemical binding]; other site
879088005253	active site
879088005254	catalytic residues [active]
879088005255	heterodimer interface [polypeptide binding]; other site
879088005256	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
879088005257	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
879088005258	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005259	catalytic residue [active]
879088005260	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
879088005261	active site
879088005262	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
879088005263	active site
879088005264	ribulose/triose binding site [chemical binding]; other site
879088005265	phosphate binding site [ion binding]; other site
879088005266	substrate (anthranilate) binding pocket [chemical binding]; other site
879088005267	product (indole) binding pocket [chemical binding]; other site
879088005268	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
879088005269	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
879088005270	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
879088005271	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
879088005272	Glutamine amidotransferase class-I; Region: GATase; pfam00117
879088005273	glutamine binding [chemical binding]; other site
879088005274	catalytic triad [active]
879088005275	anthranilate synthase component I; Provisional; Region: PRK13570
879088005276	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
879088005277	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
879088005278	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
879088005279	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
879088005280	putative catalytic cysteine [active]
879088005281	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
879088005282	putative active site [active]
879088005283	metal binding site [ion binding]; metal-binding site
879088005284	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
879088005285	dimer interface [polypeptide binding]; other site
879088005286	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088005287	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088005288	Walker A/P-loop; other site
879088005289	ATP binding site [chemical binding]; other site
879088005290	Q-loop/lid; other site
879088005291	ABC transporter signature motif; other site
879088005292	Walker B; other site
879088005293	D-loop; other site
879088005294	H-loop/switch region; other site
879088005295	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
879088005296	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
879088005297	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
879088005298	putative dimer interface [polypeptide binding]; other site
879088005299	catalytic triad [active]
879088005300	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
879088005301	aconitate hydratase; Validated; Region: PRK09277
879088005302	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
879088005303	substrate binding site [chemical binding]; other site
879088005304	ligand binding site [chemical binding]; other site
879088005305	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
879088005306	substrate binding site [chemical binding]; other site
879088005307	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088005308	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
879088005309	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
879088005310	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088005311	ATP binding site [chemical binding]; other site
879088005312	putative Mg++ binding site [ion binding]; other site
879088005313	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088005314	nucleotide binding region [chemical binding]; other site
879088005315	ATP-binding site [chemical binding]; other site
879088005316	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
879088005317	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
879088005318	Walker A/P-loop; other site
879088005319	ATP binding site [chemical binding]; other site
879088005320	Q-loop/lid; other site
879088005321	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
879088005322	ABC transporter signature motif; other site
879088005323	Walker B; other site
879088005324	D-loop; other site
879088005325	H-loop/switch region; other site
879088005326	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
879088005327	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
879088005328	active site
879088005329	metal binding site [ion binding]; metal-binding site
879088005330	DNA binding site [nucleotide binding]
879088005331	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
879088005332	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
879088005333	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
879088005334	putative acyl-acceptor binding pocket; other site
879088005335	Membrane protein involved in cytochrome C biogenesis [Posttranslational modification, protein turnover, chaperones]; Region: CcdC; COG4846
879088005336	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088005337	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088005338	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
879088005339	Walker A/P-loop; other site
879088005340	ATP binding site [chemical binding]; other site
879088005341	Q-loop/lid; other site
879088005342	ABC transporter signature motif; other site
879088005343	Walker B; other site
879088005344	D-loop; other site
879088005345	H-loop/switch region; other site
879088005346	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088005347	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
879088005348	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088005349	Walker A/P-loop; other site
879088005350	ATP binding site [chemical binding]; other site
879088005351	Q-loop/lid; other site
879088005352	ABC transporter signature motif; other site
879088005353	Walker B; other site
879088005354	D-loop; other site
879088005355	H-loop/switch region; other site
879088005356	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
879088005357	elongation factor Ts; Provisional; Region: tsf; PRK09377
879088005358	UBA/TS-N domain; Region: UBA; pfam00627
879088005359	Elongation factor TS; Region: EF_TS; pfam00889
879088005360	Elongation factor TS; Region: EF_TS; pfam00889
879088005361	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
879088005362	rRNA interaction site [nucleotide binding]; other site
879088005363	S8 interaction site; other site
879088005364	putative laminin-1 binding site; other site
879088005365	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
879088005366	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
879088005367	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
879088005368	active site turn [active]
879088005369	phosphorylation site [posttranslational modification]
879088005370	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
879088005371	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
879088005372	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
879088005373	putative active site [active]
879088005374	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088005375	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088005376	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088005377	putative active site [active]
879088005378	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
879088005379	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
879088005380	HIGH motif; other site
879088005381	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
879088005382	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
879088005383	active site
879088005384	KMSKS motif; other site
879088005385	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
879088005386	tRNA binding surface [nucleotide binding]; other site
879088005387	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
879088005388	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
879088005389	FeS/SAM binding site; other site
879088005390	Methyltransferase domain; Region: Methyltransf_31; pfam13847
879088005391	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005392	S-adenosylmethionine binding site [chemical binding]; other site
879088005393	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
879088005394	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
879088005395	active site
879088005396	dimer interface [polypeptide binding]; other site
879088005397	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
879088005398	Ligand Binding Site [chemical binding]; other site
879088005399	Molecular Tunnel; other site
879088005400	S-adenosylmethionine synthetase; Validated; Region: PRK05250
879088005401	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
879088005402	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
879088005403	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
879088005404	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
879088005405	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
879088005406	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
879088005407	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088005408	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
879088005409	NAD binding site [chemical binding]; other site
879088005410	dimer interface [polypeptide binding]; other site
879088005411	substrate binding site [chemical binding]; other site
879088005412	Protein of unknown function (DUF2584); Region: DUF2584; pfam10763
879088005413	nucleoside triphosphatase YtkD; Region: nudix_YtkD; TIGR02705
879088005414	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665
879088005415	nudix motif; other site
879088005416	Uncharacterized conserved protein [Function unknown]; Region: COG0759
879088005417	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
879088005418	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
879088005419	metal binding site [ion binding]; metal-binding site
879088005420	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
879088005421	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
879088005422	acyl-activating enzyme (AAE) consensus motif; other site
879088005423	putative AMP binding site [chemical binding]; other site
879088005424	putative active site [active]
879088005425	putative CoA binding site [chemical binding]; other site
879088005426	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
879088005427	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
879088005428	substrate binding site [chemical binding]; other site
879088005429	oxyanion hole (OAH) forming residues; other site
879088005430	trimer interface [polypeptide binding]; other site
879088005431	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088005432	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
879088005433	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
879088005434	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism]; Region: MenD; COG1165
879088005435	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
879088005436	dimer interface [polypeptide binding]; other site
879088005437	tetramer interface [polypeptide binding]; other site
879088005438	PYR/PP interface [polypeptide binding]; other site
879088005439	TPP binding site [chemical binding]; other site
879088005440	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
879088005441	TPP-binding site; other site
879088005442	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
879088005443	chorismate binding enzyme; Region: Chorismate_bind; cl10555
879088005444	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
879088005445	UbiA prenyltransferase family; Region: UbiA; pfam01040
879088005446	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
879088005447	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
879088005448	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
879088005449	FAD binding site [chemical binding]; other site
879088005450	cystathionine beta-lyase; Provisional; Region: PRK08064
879088005451	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
879088005452	homodimer interface [polypeptide binding]; other site
879088005453	substrate-cofactor binding pocket; other site
879088005454	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005455	catalytic residue [active]
879088005456	cystathionine gamma-synthase; Reviewed; Region: PRK08247
879088005457	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
879088005458	homodimer interface [polypeptide binding]; other site
879088005459	substrate-cofactor binding pocket; other site
879088005460	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005461	catalytic residue [active]
879088005462	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
879088005463	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
879088005464	THF binding site; other site
879088005465	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
879088005466	substrate binding site [chemical binding]; other site
879088005467	THF binding site; other site
879088005468	zinc-binding site [ion binding]; other site
879088005469	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088005470	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088005471	putative substrate translocation pore; other site
879088005472	ferric uptake regulator; Provisional; Region: fur; PRK09462
879088005473	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
879088005474	metal binding site 2 [ion binding]; metal-binding site
879088005475	putative DNA binding helix; other site
879088005476	metal binding site 1 [ion binding]; metal-binding site
879088005477	dimer interface [polypeptide binding]; other site
879088005478	structural Zn2+ binding site [ion binding]; other site
879088005479	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
879088005480	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
879088005481	NAD binding site [chemical binding]; other site
879088005482	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389
879088005483	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
879088005484	inhibitor-cofactor binding pocket; inhibition site
879088005485	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088005486	catalytic residue [active]
879088005487	Predicted membrane protein [Function unknown]; Region: COG4129
879088005488	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
879088005489	hypothetical protein; Provisional; Region: PRK13662
879088005490	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08063
879088005491	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
879088005492	putative NAD(P) binding site [chemical binding]; other site
879088005493	active site
879088005494	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
879088005495	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
879088005496	minor groove reading motif; other site
879088005497	helix-hairpin-helix signature motif; other site
879088005498	substrate binding pocket [chemical binding]; other site
879088005499	active site
879088005500	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
879088005501	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
879088005502	DNA binding and oxoG recognition site [nucleotide binding]
879088005503	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
879088005504	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
879088005505	trimer interface [polypeptide binding]; other site
879088005506	active site
879088005507	WVELL protein; Region: WVELL; pfam14043
879088005508	recombination regulator RecX; Provisional; Region: recX; PRK14135
879088005509	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
879088005510	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
879088005511	NAD(P) binding site [chemical binding]; other site
879088005512	active site
879088005513	Predicted integral membrane protein [Function unknown]; Region: COG0392
879088005514	Uncharacterized conserved protein [Function unknown]; Region: COG2898
879088005515	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
879088005516	Glycopeptide antibiotics resistance protein [Defense mechanisms]; Region: VanZ; COG4767
879088005517	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
879088005518	Cation efflux family; Region: Cation_efflux; pfam01545
879088005519	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
879088005520	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
879088005521	PAS fold; Region: PAS_4; pfam08448
879088005522	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
879088005523	putative active site [active]
879088005524	heme pocket [chemical binding]; other site
879088005525	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
879088005526	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
879088005527	dimer interface [polypeptide binding]; other site
879088005528	putative CheW interface [polypeptide binding]; other site
879088005529	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
879088005530	FosX, a fosfomycin resistance protein, catalyzes the addition of a water molecule to the C1 position of the antibiotic with inversion of configuration at C1; Region: FosX; cd08364
879088005531	dimer interface [polypeptide binding]; other site
879088005532	active site
879088005533	Mn binding site [ion binding]; other site
879088005534	TRAM domain; Region: TRAM; cl01282
879088005535	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
879088005536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005537	S-adenosylmethionine binding site [chemical binding]; other site
879088005538	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
879088005539	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
879088005540	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
879088005541	Substrate-binding site [chemical binding]; other site
879088005542	Substrate specificity [chemical binding]; other site
879088005543	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
879088005544	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4840
879088005545	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
879088005546	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
879088005547	active site
879088005548	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
879088005549	flavodoxin, short chain; Region: flav_short; TIGR01753
879088005550	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
879088005551	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
879088005552	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088005553	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088005554	putative substrate translocation pore; other site
879088005555	rod-share determining protein MreBH; Provisional; Region: PRK13929
879088005556	MreB and similar proteins; Region: MreB_like; cd10225
879088005557	nucleotide binding site [chemical binding]; other site
879088005558	Mg binding site [ion binding]; other site
879088005559	putative protofilament interaction site [polypeptide binding]; other site
879088005560	RodZ interaction site [polypeptide binding]; other site
879088005561	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005562	S-adenosylmethionine binding site [chemical binding]; other site
879088005563	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088005564	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088005565	Uncharacterized conserved protein [Function unknown]; Region: COG3589
879088005566	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
879088005567	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088005568	methionine cluster; other site
879088005569	active site
879088005570	phosphorylation site [posttranslational modification]
879088005571	metal binding site [ion binding]; metal-binding site
879088005572	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088005573	active site
879088005574	P-loop; other site
879088005575	phosphorylation site [posttranslational modification]
879088005576	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
879088005577	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088005578	Walker A motif; other site
879088005579	ATP binding site [chemical binding]; other site
879088005580	Walker B motif; other site
879088005581	arginine finger; other site
879088005582	Transcriptional antiterminator [Transcription]; Region: COG3933
879088005583	PRD domain; Region: PRD; pfam00874
879088005584	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088005585	active pocket/dimerization site; other site
879088005586	active site
879088005587	phosphorylation site [posttranslational modification]
879088005588	PRD domain; Region: PRD; pfam00874
879088005589	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
879088005590	DEAD-like helicases superfamily; Region: DEXDc; smart00487
879088005591	ATP binding site [chemical binding]; other site
879088005592	putative Mg++ binding site [ion binding]; other site
879088005593	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088005594	nucleotide binding region [chemical binding]; other site
879088005595	ATP-binding site [chemical binding]; other site
879088005596	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
879088005597	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088005598	Walker A/P-loop; other site
879088005599	ATP binding site [chemical binding]; other site
879088005600	Q-loop/lid; other site
879088005601	ABC transporter signature motif; other site
879088005602	Walker B; other site
879088005603	D-loop; other site
879088005604	H-loop/switch region; other site
879088005605	Predicted transcriptional regulators [Transcription]; Region: COG1725
879088005606	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088005607	DNA-binding site [nucleotide binding]; DNA binding site
879088005608	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088005609	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088005610	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088005611	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088005612	DNA binding site [nucleotide binding]
879088005613	domain linker motif; other site
879088005614	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
879088005615	dimerization interface [polypeptide binding]; other site
879088005616	ligand binding site [chemical binding]; other site
879088005617	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
879088005618	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
879088005619	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
879088005620	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
879088005621	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
879088005622	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088005623	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088005624	dimer interface [polypeptide binding]; other site
879088005625	conserved gate region; other site
879088005626	putative PBP binding loops; other site
879088005627	ABC-ATPase subunit interface; other site
879088005628	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088005629	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088005630	dimer interface [polypeptide binding]; other site
879088005631	conserved gate region; other site
879088005632	putative PBP binding loops; other site
879088005633	ABC-ATPase subunit interface; other site
879088005634	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
879088005635	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
879088005636	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
879088005637	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
879088005638	active site
879088005639	dimer interface [polypeptide binding]; other site
879088005640	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
879088005641	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
879088005642	active site
879088005643	FMN binding site [chemical binding]; other site
879088005644	substrate binding site [chemical binding]; other site
879088005645	3Fe-4S cluster binding site [ion binding]; other site
879088005646	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
879088005647	domain interface; other site
879088005648	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088005649	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088005650	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
879088005651	putative dimerization interface [polypeptide binding]; other site
879088005652	Predicted acetyltransferase [General function prediction only]; Region: COG3153
879088005653	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
879088005654	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
879088005655	putative active site [active]
879088005656	metal binding site [ion binding]; metal-binding site
879088005657	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
879088005658	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
879088005659	substrate binding pocket [chemical binding]; other site
879088005660	membrane-bound complex binding site; other site
879088005661	hinge residues; other site
879088005662	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088005663	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088005664	Walker A/P-loop; other site
879088005665	ATP binding site [chemical binding]; other site
879088005666	Q-loop/lid; other site
879088005667	ABC transporter signature motif; other site
879088005668	Walker B; other site
879088005669	D-loop; other site
879088005670	H-loop/switch region; other site
879088005671	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088005672	dimer interface [polypeptide binding]; other site
879088005673	conserved gate region; other site
879088005674	putative PBP binding loops; other site
879088005675	ABC-ATPase subunit interface; other site
879088005676	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
879088005677	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
879088005678	dimer interface [polypeptide binding]; other site
879088005679	phosphorylation site [posttranslational modification]
879088005680	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088005681	ATP binding site [chemical binding]; other site
879088005682	Mg2+ binding site [ion binding]; other site
879088005683	G-X-G motif; other site
879088005684	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
879088005685	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
879088005686	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
879088005687	active site
879088005688	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
879088005689	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
879088005690	putative NAD(P) binding site [chemical binding]; other site
879088005691	active site
879088005692	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088005693	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088005694	active site
879088005695	phosphorylation site [posttranslational modification]
879088005696	intermolecular recognition site; other site
879088005697	dimerization interface [polypeptide binding]; other site
879088005698	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088005699	DNA binding site [nucleotide binding]
879088005700	FtsX-like permease family; Region: FtsX; pfam02687
879088005701	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088005702	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088005703	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088005704	Walker A/P-loop; other site
879088005705	ATP binding site [chemical binding]; other site
879088005706	Q-loop/lid; other site
879088005707	ABC transporter signature motif; other site
879088005708	Walker B; other site
879088005709	D-loop; other site
879088005710	H-loop/switch region; other site
879088005711	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
879088005712	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
879088005713	ADP binding site [chemical binding]; other site
879088005714	magnesium binding site [ion binding]; other site
879088005715	putative shikimate binding site; other site
879088005716	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
879088005717	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
879088005718	TRAM domain; Region: TRAM; pfam01938
879088005719	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005720	S-adenosylmethionine binding site [chemical binding]; other site
879088005721	putative lipid kinase; Reviewed; Region: PRK13337
879088005722	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
879088005723	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
879088005724	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
879088005725	GatB domain; Region: GatB_Yqey; smart00845
879088005726	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
879088005727	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
879088005728	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
879088005729	Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851
879088005730	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
879088005731	putative dimer interface [polypeptide binding]; other site
879088005732	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
879088005733	putative dimer interface [polypeptide binding]; other site
879088005734	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
879088005735	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
879088005736	nucleotide binding pocket [chemical binding]; other site
879088005737	K-X-D-G motif; other site
879088005738	catalytic site [active]
879088005739	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
879088005740	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
879088005741	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
879088005742	Dimer interface [polypeptide binding]; other site
879088005743	BRCT sequence motif; other site
879088005744	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
879088005745	Part of AAA domain; Region: AAA_19; pfam13245
879088005746	Family description; Region: UvrD_C_2; pfam13538
879088005747	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
879088005748	PcrB family; Region: PcrB; pfam01884
879088005749	substrate binding site [chemical binding]; other site
879088005750	putative active site [active]
879088005751	dimer interface [polypeptide binding]; other site
879088005752	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
879088005753	Na2 binding site [ion binding]; other site
879088005754	putative substrate binding site 1 [chemical binding]; other site
879088005755	Na binding site 1 [ion binding]; other site
879088005756	putative substrate binding site 2 [chemical binding]; other site
879088005757	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4496
879088005758	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
879088005759	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
879088005760	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
879088005761	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
879088005762	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
879088005763	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
879088005764	purine monophosphate binding site [chemical binding]; other site
879088005765	dimer interface [polypeptide binding]; other site
879088005766	putative catalytic residues [active]
879088005767	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
879088005768	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
879088005769	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
879088005770	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
879088005771	active site
879088005772	substrate binding site [chemical binding]; other site
879088005773	cosubstrate binding site; other site
879088005774	catalytic site [active]
879088005775	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
879088005776	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
879088005777	dimerization interface [polypeptide binding]; other site
879088005778	putative ATP binding site [chemical binding]; other site
879088005779	amidophosphoribosyltransferase; Provisional; Region: PRK06781
879088005780	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
879088005781	active site
879088005782	tetramer interface [polypeptide binding]; other site
879088005783	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088005784	active site
879088005785	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
879088005786	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
879088005787	dimerization interface [polypeptide binding]; other site
879088005788	ATP binding site [chemical binding]; other site
879088005789	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
879088005790	dimerization interface [polypeptide binding]; other site
879088005791	ATP binding site [chemical binding]; other site
879088005792	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
879088005793	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
879088005794	putative active site [active]
879088005795	catalytic triad [active]
879088005796	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
879088005797	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
879088005798	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
879088005799	ATP binding site [chemical binding]; other site
879088005800	active site
879088005801	substrate binding site [chemical binding]; other site
879088005802	adenylosuccinate lyase; Provisional; Region: PRK07492
879088005803	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
879088005804	tetramer interface [polypeptide binding]; other site
879088005805	active site
879088005806	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
879088005807	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
879088005808	NAD binding site [chemical binding]; other site
879088005809	ATP-grasp domain; Region: ATP-grasp; pfam02222
879088005810	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
879088005811	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4843
879088005812	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088005813	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
879088005814	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088005815	Zn2+ binding site [ion binding]; other site
879088005816	Mg2+ binding site [ion binding]; other site
879088005817	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
879088005818	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
879088005819	Walker A/P-loop; other site
879088005820	ATP binding site [chemical binding]; other site
879088005821	Q-loop/lid; other site
879088005822	ABC transporter signature motif; other site
879088005823	Walker B; other site
879088005824	D-loop; other site
879088005825	H-loop/switch region; other site
879088005826	peptidase T; Region: peptidase-T; TIGR01882
879088005827	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
879088005828	metal binding site [ion binding]; metal-binding site
879088005829	dimer interface [polypeptide binding]; other site
879088005830	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3797
879088005831	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
879088005832	active site
879088005833	putative catalytic site [active]
879088005834	DNA binding site [nucleotide binding]
879088005835	putative phosphate binding site [ion binding]; other site
879088005836	metal binding site A [ion binding]; metal-binding site
879088005837	AP binding site [nucleotide binding]; other site
879088005838	metal binding site B [ion binding]; metal-binding site
879088005839	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
879088005840	23S rRNA binding site [nucleotide binding]; other site
879088005841	L21 binding site [polypeptide binding]; other site
879088005842	L13 binding site [polypeptide binding]; other site
879088005843	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
879088005844	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
879088005845	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
879088005846	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
879088005847	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088005848	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088005849	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088005850	Substrate binding site [chemical binding]; other site
879088005851	Leucine rich repeat; Region: LRR_8; pfam13855
879088005852	LRR adjacent; Region: LRR_adjacent; pfam08191
879088005853	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
879088005854	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
879088005855	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
879088005856	DNA binding residues [nucleotide binding]
879088005857	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
879088005858	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
879088005859	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088005860	Putative heavy-metal-binding; Region: YbjQ_1; pfam01906
879088005861	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
879088005862	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
879088005863	RimM N-terminal domain; Region: RimM; pfam01782
879088005864	PRC-barrel domain; Region: PRC; pfam05239
879088005865	Protein of unknown function (DUF2869); Region: DUF2869; pfam11068
879088005866	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
879088005867	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
879088005868	catalytic triad [active]
879088005869	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
879088005870	KH domain; Region: KH_4; pfam13083
879088005871	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
879088005872	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
879088005873	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
879088005874	signal recognition particle protein; Provisional; Region: PRK10867
879088005875	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
879088005876	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
879088005877	P loop; other site
879088005878	GTP binding site [chemical binding]; other site
879088005879	Signal peptide binding domain; Region: SRP_SPB; pfam02978
879088005880	putative DNA-binding protein; Validated; Region: PRK00118
879088005881	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
879088005882	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
879088005883	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
879088005884	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
879088005885	P loop; other site
879088005886	GTP binding site [chemical binding]; other site
879088005887	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
879088005888	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
879088005889	Walker A/P-loop; other site
879088005890	ATP binding site [chemical binding]; other site
879088005891	Q-loop/lid; other site
879088005892	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
879088005893	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
879088005894	linker region; other site
879088005895	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
879088005896	ABC transporter signature motif; other site
879088005897	Walker B; other site
879088005898	D-loop; other site
879088005899	H-loop/switch region; other site
879088005900	ribonuclease III; Reviewed; Region: rnc; PRK00102
879088005901	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
879088005902	dimerization interface [polypeptide binding]; other site
879088005903	active site
879088005904	metal binding site [ion binding]; metal-binding site
879088005905	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
879088005906	dsRNA binding site [nucleotide binding]; other site
879088005907	acyl carrier protein; Provisional; Region: acpP; PRK00982
879088005908	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
879088005909	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
879088005910	NAD(P) binding site [chemical binding]; other site
879088005911	homotetramer interface [polypeptide binding]; other site
879088005912	homodimer interface [polypeptide binding]; other site
879088005913	active site
879088005914	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
879088005915	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
879088005916	putative phosphate acyltransferase; Provisional; Region: PRK05331
879088005917	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
879088005918	HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]; Region: PaaI; COG2050
879088005919	active site 2 [active]
879088005920	active site 1 [active]
879088005921	Y-family of DNA polymerases; Region: PolY; cl12025
879088005922	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
879088005923	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
879088005924	generic binding surface II; other site
879088005925	ssDNA binding site; other site
879088005926	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088005927	ATP binding site [chemical binding]; other site
879088005928	putative Mg++ binding site [ion binding]; other site
879088005929	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088005930	nucleotide binding region [chemical binding]; other site
879088005931	ATP-binding site [chemical binding]; other site
879088005932	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
879088005933	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
879088005934	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
879088005935	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
879088005936	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
879088005937	putative L-serine binding site [chemical binding]; other site
879088005938	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
879088005939	DAK2 domain; Region: Dak2; pfam02734
879088005940	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
879088005941	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
879088005942	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
879088005943	Thiamine pyrophosphokinase; Region: TPK; cd07995
879088005944	active site
879088005945	dimerization interface [polypeptide binding]; other site
879088005946	thiamine binding site [chemical binding]; other site
879088005947	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
879088005948	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
879088005949	substrate binding site [chemical binding]; other site
879088005950	hexamer interface [polypeptide binding]; other site
879088005951	metal binding site [ion binding]; metal-binding site
879088005952	GTPase RsgA; Reviewed; Region: PRK00098
879088005953	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
879088005954	RNA binding site [nucleotide binding]; other site
879088005955	homodimer interface [polypeptide binding]; other site
879088005956	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
879088005957	GTPase/Zn-binding domain interface [polypeptide binding]; other site
879088005958	GTP/Mg2+ binding site [chemical binding]; other site
879088005959	G4 box; other site
879088005960	G1 box; other site
879088005961	Switch I region; other site
879088005962	G2 box; other site
879088005963	G3 box; other site
879088005964	Switch II region; other site
879088005965	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
879088005966	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
879088005967	active site
879088005968	ATP binding site [chemical binding]; other site
879088005969	substrate binding site [chemical binding]; other site
879088005970	activation loop (A-loop); other site
879088005971	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
879088005972	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
879088005973	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
879088005974	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
879088005975	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
879088005976	Protein phosphatase 2C; Region: PP2C; pfam00481
879088005977	active site
879088005978	16S rRNA methyltransferase B; Provisional; Region: PRK14902
879088005979	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
879088005980	putative RNA binding site [nucleotide binding]; other site
879088005981	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088005982	S-adenosylmethionine binding site [chemical binding]; other site
879088005983	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
879088005984	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
879088005985	putative active site [active]
879088005986	substrate binding site [chemical binding]; other site
879088005987	putative cosubstrate binding site; other site
879088005988	catalytic site [active]
879088005989	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
879088005990	substrate binding site [chemical binding]; other site
879088005991	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
879088005992	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088005993	ATP binding site [chemical binding]; other site
879088005994	putative Mg++ binding site [ion binding]; other site
879088005995	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088005996	ATP-binding site [chemical binding]; other site
879088005997	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
879088005998	Flavoprotein; Region: Flavoprotein; pfam02441
879088005999	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
879088006000	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
879088006001	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
879088006002	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
879088006003	catalytic site [active]
879088006004	G-X2-G-X-G-K; other site
879088006005	Uncharacterized stress-induced protein [Function unknown]; Region: COG1561
879088006006	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
879088006007	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
879088006008	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
879088006009	Domain of unknown function (DUF814); Region: DUF814; pfam05670
879088006010	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
879088006011	putative NAD(P) binding site [chemical binding]; other site
879088006012	homodimer interface [polypeptide binding]; other site
879088006013	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088006014	active site
879088006015	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
879088006016	active site
879088006017	dimer interface [polypeptide binding]; other site
879088006018	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
879088006019	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
879088006020	heterodimer interface [polypeptide binding]; other site
879088006021	active site
879088006022	FMN binding site [chemical binding]; other site
879088006023	homodimer interface [polypeptide binding]; other site
879088006024	substrate binding site [chemical binding]; other site
879088006025	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
879088006026	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
879088006027	FAD binding pocket [chemical binding]; other site
879088006028	FAD binding motif [chemical binding]; other site
879088006029	phosphate binding motif [ion binding]; other site
879088006030	beta-alpha-beta structure motif; other site
879088006031	NAD binding pocket [chemical binding]; other site
879088006032	Iron coordination center [ion binding]; other site
879088006033	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
879088006034	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
879088006035	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
879088006036	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
879088006037	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
879088006038	ATP-grasp domain; Region: ATP-grasp_4; cl17255
879088006039	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
879088006040	IMP binding site; other site
879088006041	dimer interface [polypeptide binding]; other site
879088006042	interdomain contacts; other site
879088006043	partial ornithine binding site; other site
879088006044	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
879088006045	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
879088006046	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
879088006047	catalytic site [active]
879088006048	subunit interface [polypeptide binding]; other site
879088006049	dihydroorotase; Validated; Region: pyrC; PRK09357
879088006050	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
879088006051	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
879088006052	active site
879088006053	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
879088006054	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
879088006055	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
879088006056	uracil transporter; Provisional; Region: PRK10720
879088006057	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
879088006058	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088006059	active site
879088006060	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
879088006061	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
879088006062	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088006063	RNA binding surface [nucleotide binding]; other site
879088006064	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
879088006065	active site
879088006066	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
879088006067	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
879088006068	Sulfate transporter family; Region: Sulfate_transp; pfam00916
879088006069	multidrug efflux protein; Reviewed; Region: PRK01766
879088006070	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
879088006071	cation binding site [ion binding]; other site
879088006072	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
879088006073	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
879088006074	metal binding site [ion binding]; metal-binding site
879088006075	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
879088006076	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088006077	ABC-ATPase subunit  interface; other site
879088006078	dimer interface [polypeptide binding]; other site
879088006079	putative PBP binding regions; other site
879088006080	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
879088006081	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
879088006082	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088006083	MarR family; Region: MarR; pfam01047
879088006084	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
879088006085	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
879088006086	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
879088006087	protein binding site [polypeptide binding]; other site
879088006088	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
879088006089	Catalytic dyad [active]
879088006090	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
879088006091	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
879088006092	metal-binding site [ion binding]
879088006093	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
879088006094	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
879088006095	metal-binding site [ion binding]
879088006096	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088006097	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088006098	motif II; other site
879088006099	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cl00846
879088006100	putative homodimer interface [polypeptide binding]; other site
879088006101	putative homotetramer interface [polypeptide binding]; other site
879088006102	putative allosteric switch controlling residues; other site
879088006103	putative metal binding site [ion binding]; other site
879088006104	putative homodimer-homodimer interface [polypeptide binding]; other site
879088006105	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
879088006106	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
879088006107	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
879088006108	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
879088006109	hypothetical protein; Provisional; Region: PRK13672
879088006110	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088006111	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088006112	methionine sulfoxide reductase B; Provisional; Region: PRK00222
879088006113	SelR domain; Region: SelR; pfam01641
879088006114	methionine sulfoxide reductase A; Provisional; Region: PRK14054
879088006115	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4698
879088006116	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
879088006117	active site
879088006118	catalytic triad [active]
879088006119	oxyanion hole [active]
879088006120	EDD domain protein, DegV family; Region: DegV; TIGR00762
879088006121	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
879088006122	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
879088006123	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
879088006124	HTH domain; Region: HTH_11; pfam08279
879088006125	FOG: CBS domain [General function prediction only]; Region: COG0517
879088006126	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
879088006127	PEP synthetase regulatory protein; Provisional; Region: PRK05339
879088006128	pyruvate phosphate dikinase; Provisional; Region: PRK09279
879088006129	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
879088006130	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
879088006131	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
879088006132	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088006133	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
879088006134	Predicted membrane protein [Function unknown]; Region: COG4129
879088006135	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
879088006136	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
879088006137	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
879088006138	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
879088006139	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
879088006140	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
879088006141	Clostridial hydrophobic, with a conserved W residue, domain; Region: ChW; smart00728
879088006142	Clostridial hydrophobic W; Region: ChW; pfam07538
879088006143	Clostridial hydrophobic W; Region: ChW; pfam07538
879088006144	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
879088006145	active site
879088006146	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
879088006147	substrate binding site [chemical binding]; other site
879088006148	metal binding site [ion binding]; metal-binding site
879088006149	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
879088006150	Methyltransferase domain; Region: Methyltransf_18; pfam12847
879088006151	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
879088006152	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
879088006153	folate binding site [chemical binding]; other site
879088006154	NADP+ binding site [chemical binding]; other site
879088006155	thymidylate synthase; Region: thym_sym; TIGR03284
879088006156	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
879088006157	dimerization interface [polypeptide binding]; other site
879088006158	active site
879088006159	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
879088006160	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
879088006161	Walker A/P-loop; other site
879088006162	ATP binding site [chemical binding]; other site
879088006163	Q-loop/lid; other site
879088006164	ABC transporter signature motif; other site
879088006165	Walker B; other site
879088006166	D-loop; other site
879088006167	H-loop/switch region; other site
879088006168	ABC transporter; Region: ABC_tran_2; pfam12848
879088006169	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088006170	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
879088006171	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
879088006172	Potassium binding sites [ion binding]; other site
879088006173	Cesium cation binding sites [ion binding]; other site
879088006174	manganese transport transcriptional regulator; Provisional; Region: PRK03902
879088006175	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
879088006176	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
879088006177	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
879088006178	DNA-binding site [nucleotide binding]; DNA binding site
879088006179	RNA-binding motif; other site
879088006180	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
879088006181	RNA/DNA hybrid binding site [nucleotide binding]; other site
879088006182	active site
879088006183	5'-3' exonuclease; Region: 53EXOc; smart00475
879088006184	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
879088006185	active site
879088006186	metal binding site 1 [ion binding]; metal-binding site
879088006187	putative 5' ssDNA interaction site; other site
879088006188	metal binding site 3; metal-binding site
879088006189	metal binding site 2 [ion binding]; metal-binding site
879088006190	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
879088006191	putative DNA binding site [nucleotide binding]; other site
879088006192	putative metal binding site [ion binding]; other site
879088006193	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
879088006194	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
879088006195	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
879088006196	putative active site [active]
879088006197	xanthine permease; Region: pbuX; TIGR03173
879088006198	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088006199	active site
879088006200	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
879088006201	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
879088006202	active site
879088006203	Zn binding site [ion binding]; other site
879088006204	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
879088006205	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
879088006206	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
879088006207	cell division protein GpsB; Provisional; Region: PRK14127
879088006208	DivIVA domain; Region: DivI1A_domain; TIGR03544
879088006209	Interactor of ZYG-11; Region: ZYG-11_interact; pfam05884
879088006210	hypothetical protein; Provisional; Region: PRK13660
879088006211	Bacterial domain of unknown function (DUF1798); Region: DUF1798; pfam08807
879088006212	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
879088006213	Transglycosylase; Region: Transgly; pfam00912
879088006214	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
879088006215	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
879088006216	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
879088006217	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
879088006218	minor groove reading motif; other site
879088006219	helix-hairpin-helix signature motif; other site
879088006220	substrate binding pocket [chemical binding]; other site
879088006221	active site
879088006222	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
879088006223	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
879088006224	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
879088006225	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
879088006226	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
879088006227	putative dimer interface [polypeptide binding]; other site
879088006228	putative anticodon binding site; other site
879088006229	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
879088006230	homodimer interface [polypeptide binding]; other site
879088006231	motif 1; other site
879088006232	motif 2; other site
879088006233	active site
879088006234	motif 3; other site
879088006235	aspartate aminotransferase; Provisional; Region: PRK05764
879088006236	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088006237	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088006238	homodimer interface [polypeptide binding]; other site
879088006239	catalytic residue [active]
879088006240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
879088006241	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
879088006242	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
879088006243	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
879088006244	active site
879088006245	catalytic site [active]
879088006246	substrate binding site [chemical binding]; other site
879088006247	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
879088006248	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
879088006249	putative Mg++ binding site [ion binding]; other site
879088006250	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
879088006251	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
879088006252	tetramerization interface [polypeptide binding]; other site
879088006253	active site
879088006254	pantoate--beta-alanine ligase; Region: panC; TIGR00018
879088006255	Pantoate-beta-alanine ligase; Region: PanC; cd00560
879088006256	active site
879088006257	ATP-binding site [chemical binding]; other site
879088006258	pantoate-binding site; other site
879088006259	HXXH motif; other site
879088006260	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
879088006261	active site
879088006262	oligomerization interface [polypeptide binding]; other site
879088006263	metal binding site [ion binding]; metal-binding site
879088006264	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088006265	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
879088006266	catalytic residues [active]
879088006267	Biotin operon repressor [Transcription]; Region: BirA; COG1654
879088006268	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
879088006269	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
879088006270	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
879088006271	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
879088006272	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
879088006273	active site
879088006274	NTP binding site [chemical binding]; other site
879088006275	metal binding triad [ion binding]; metal-binding site
879088006276	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
879088006277	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
879088006278	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
879088006279	active site
879088006280	dimer interfaces [polypeptide binding]; other site
879088006281	catalytic residues [active]
879088006282	dihydrodipicolinate reductase; Provisional; Region: PRK00048
879088006283	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
879088006284	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
879088006285	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
879088006286	homodimer interface [polypeptide binding]; other site
879088006287	metal binding site [ion binding]; metal-binding site
879088006288	Uncharacterized conserved protein [Function unknown]; Region: COG1284
879088006289	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088006290	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088006291	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088006292	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
879088006293	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
879088006294	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
879088006295	metal binding site [ion binding]; metal-binding site
879088006296	active site
879088006297	I-site; other site
879088006298	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
879088006299	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
879088006300	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
879088006301	metal binding site [ion binding]; metal-binding site
879088006302	active site
879088006303	I-site; other site
879088006304	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
879088006305	malate dehydrogenase; Provisional; Region: PRK13529
879088006306	Malic enzyme, N-terminal domain; Region: malic; pfam00390
879088006307	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
879088006308	NAD(P) binding pocket [chemical binding]; other site
879088006309	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
879088006310	Beta-lactamase; Region: Beta-lactamase; pfam00144
879088006311	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
879088006312	Pyruvate formate lyase 1; Region: PFL1; cd01678
879088006313	coenzyme A binding site [chemical binding]; other site
879088006314	active site
879088006315	catalytic residues [active]
879088006316	glycine loop; other site
879088006317	HI0933-like protein; Region: HI0933_like; pfam03486
879088006318	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088006319	Predicted Zn-dependent protease [General function prediction only]; Region: COG2738
879088006320	Predicted membrane protein [Function unknown]; Region: COG4347
879088006321	hypothetical protein; Provisional; Region: PRK03636
879088006322	UPF0302 domain; Region: UPF0302; pfam08864
879088006323	IDEAL domain; Region: IDEAL; pfam08858
879088006324	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
879088006325	binding surface
879088006326	TPR motif; other site
879088006327	TPR repeat; Region: TPR_11; pfam13414
879088006328	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088006329	binding surface
879088006330	TPR motif; other site
879088006331	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
879088006332	binding surface
879088006333	TPR motif; other site
879088006334	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
879088006335	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
879088006336	hinge; other site
879088006337	active site
879088006338	prephenate dehydrogenase; Validated; Region: PRK06545
879088006339	prephenate dehydrogenase; Validated; Region: PRK08507
879088006340	C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909
879088006341	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
879088006342	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088006343	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088006344	homodimer interface [polypeptide binding]; other site
879088006345	catalytic residue [active]
879088006346	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
879088006347	homotrimer interaction site [polypeptide binding]; other site
879088006348	active site
879088006349	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
879088006350	active site
879088006351	dimer interface [polypeptide binding]; other site
879088006352	metal binding site [ion binding]; metal-binding site
879088006353	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
879088006354	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
879088006355	Tetramer interface [polypeptide binding]; other site
879088006356	active site
879088006357	FMN-binding site [chemical binding]; other site
879088006358	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
879088006359	active site
879088006360	multimer interface [polypeptide binding]; other site
879088006361	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
879088006362	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
879088006363	substrate binding pocket [chemical binding]; other site
879088006364	chain length determination region; other site
879088006365	substrate-Mg2+ binding site; other site
879088006366	catalytic residues [active]
879088006367	aspartate-rich region 1; other site
879088006368	active site lid residues [active]
879088006369	aspartate-rich region 2; other site
879088006370	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
879088006371	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088006372	S-adenosylmethionine binding site [chemical binding]; other site
879088006373	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307
879088006374	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
879088006375	homodecamer interface [polypeptide binding]; other site
879088006376	GTP cyclohydrolase I; Provisional; Region: PLN03044
879088006377	active site
879088006378	putative catalytic site residues [active]
879088006379	zinc binding site [ion binding]; other site
879088006380	GTP-CH-I/GFRP interaction surface; other site
879088006381	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
879088006382	IHF dimer interface [polypeptide binding]; other site
879088006383	IHF - DNA interface [nucleotide binding]; other site
879088006384	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
879088006385	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
879088006386	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
879088006387	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
879088006388	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
879088006389	GTP-binding protein Der; Reviewed; Region: PRK00093
879088006390	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
879088006391	G1 box; other site
879088006392	GTP/Mg2+ binding site [chemical binding]; other site
879088006393	Switch I region; other site
879088006394	G2 box; other site
879088006395	Switch II region; other site
879088006396	G3 box; other site
879088006397	G4 box; other site
879088006398	G5 box; other site
879088006399	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
879088006400	G1 box; other site
879088006401	GTP/Mg2+ binding site [chemical binding]; other site
879088006402	Switch I region; other site
879088006403	G2 box; other site
879088006404	G3 box; other site
879088006405	Switch II region; other site
879088006406	G4 box; other site
879088006407	G5 box; other site
879088006408	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
879088006409	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
879088006410	RNA binding site [nucleotide binding]; other site
879088006411	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
879088006412	RNA binding site [nucleotide binding]; other site
879088006413	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
879088006414	RNA binding site [nucleotide binding]; other site
879088006415	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
879088006416	RNA binding site [nucleotide binding]; other site
879088006417	cytidylate kinase; Provisional; Region: cmk; PRK00023
879088006418	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
879088006419	CMP-binding site; other site
879088006420	The sites determining sugar specificity; other site
879088006421	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
879088006422	active site
879088006423	homotetramer interface [polypeptide binding]; other site
879088006424	homodimer interface [polypeptide binding]; other site
879088006425	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088006426	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
879088006427	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
879088006428	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088006429	ATP binding site [chemical binding]; other site
879088006430	putative Mg++ binding site [ion binding]; other site
879088006431	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088006432	nucleotide binding region [chemical binding]; other site
879088006433	ATP-binding site [chemical binding]; other site
879088006434	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
879088006435	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006436	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006437	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006438	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006439	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006440	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006441	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
879088006442	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088006443	Predicted membrane protein [Function unknown]; Region: COG3601
879088006444	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
879088006445	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
879088006446	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088006447	dimerization interface [polypeptide binding]; other site
879088006448	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
879088006449	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088006450	dimer interface [polypeptide binding]; other site
879088006451	phosphorylation site [posttranslational modification]
879088006452	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088006453	ATP binding site [chemical binding]; other site
879088006454	Mg2+ binding site [ion binding]; other site
879088006455	G-X-G motif; other site
879088006456	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088006457	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088006458	active site
879088006459	phosphorylation site [posttranslational modification]
879088006460	intermolecular recognition site; other site
879088006461	dimerization interface [polypeptide binding]; other site
879088006462	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088006463	DNA binding site [nucleotide binding]
879088006464	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
879088006465	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088006466	RNA binding surface [nucleotide binding]; other site
879088006467	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
879088006468	active site
879088006469	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
879088006470	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
879088006471	diaminopimelate decarboxylase; Region: lysA; TIGR01048
879088006472	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
879088006473	active site
879088006474	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
879088006475	substrate binding site [chemical binding]; other site
879088006476	catalytic residues [active]
879088006477	dimer interface [polypeptide binding]; other site
879088006478	purine nucleoside phosphorylase; Provisional; Region: PRK08202
879088006479	phosphopentomutase; Provisional; Region: PRK05362
879088006480	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
879088006481	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
879088006482	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
879088006483	active site
879088006484	Int/Topo IB signature motif; other site
879088006485	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
879088006486	metal binding site 2 [ion binding]; metal-binding site
879088006487	putative DNA binding helix; other site
879088006488	metal binding site 1 [ion binding]; metal-binding site
879088006489	dimer interface [polypeptide binding]; other site
879088006490	structural Zn2+ binding site [ion binding]; other site
879088006491	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
879088006492	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088006493	ABC-ATPase subunit  interface; other site
879088006494	dimer interface [polypeptide binding]; other site
879088006495	putative PBP binding regions; other site
879088006496	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
879088006497	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088006498	ABC-ATPase subunit  interface; other site
879088006499	dimer interface [polypeptide binding]; other site
879088006500	putative PBP binding regions; other site
879088006501	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
879088006502	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
879088006503	putative ligand binding residues [chemical binding]; other site
879088006504	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
879088006505	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
879088006506	Walker A/P-loop; other site
879088006507	ATP binding site [chemical binding]; other site
879088006508	Q-loop/lid; other site
879088006509	ABC transporter signature motif; other site
879088006510	Walker B; other site
879088006511	D-loop; other site
879088006512	H-loop/switch region; other site
879088006513	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
879088006514	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088006515	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088006516	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088006517	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
879088006518	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
879088006519	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088006520	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088006521	Walker A/P-loop; other site
879088006522	ATP binding site [chemical binding]; other site
879088006523	Q-loop/lid; other site
879088006524	ABC transporter signature motif; other site
879088006525	Walker B; other site
879088006526	D-loop; other site
879088006527	H-loop/switch region; other site
879088006528	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
879088006529	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
879088006530	dimer interface [polypeptide binding]; other site
879088006531	ADP-ribose binding site [chemical binding]; other site
879088006532	active site
879088006533	nudix motif; other site
879088006534	metal binding site [ion binding]; metal-binding site
879088006535	5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only]; Region: XpaC; COG4915
879088006536	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
879088006537	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
879088006538	active site
879088006539	DNA polymerase IV; Validated; Region: PRK02406
879088006540	DNA binding site [nucleotide binding]
879088006541	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
879088006542	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
879088006543	NAD(P) binding site [chemical binding]; other site
879088006544	active site
879088006545	ribonuclease Z; Region: RNase_Z; TIGR02651
879088006546	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
879088006547	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
879088006548	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
879088006549	Protein of unknown function (DUF1694); Region: DUF1694; cl02318
879088006550	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
879088006551	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088006552	Coenzyme A binding pocket [chemical binding]; other site
879088006553	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
879088006554	6-phosphogluconate dehydratase; Region: edd; TIGR01196
879088006555	acetolactate synthase catalytic subunit; Reviewed; Region: PRK07710
879088006556	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
879088006557	PYR/PP interface [polypeptide binding]; other site
879088006558	dimer interface [polypeptide binding]; other site
879088006559	TPP binding site [chemical binding]; other site
879088006560	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
879088006561	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
879088006562	TPP-binding site [chemical binding]; other site
879088006563	dimer interface [polypeptide binding]; other site
879088006564	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
879088006565	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
879088006566	putative valine binding site [chemical binding]; other site
879088006567	dimer interface [polypeptide binding]; other site
879088006568	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
879088006569	ketol-acid reductoisomerase; Provisional; Region: PRK05479
879088006570	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
879088006571	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
879088006572	2-isopropylmalate synthase; Validated; Region: PRK00915
879088006573	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
879088006574	active site
879088006575	catalytic residues [active]
879088006576	metal binding site [ion binding]; metal-binding site
879088006577	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
879088006578	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
879088006579	tartrate dehydrogenase; Region: TTC; TIGR02089
879088006580	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
879088006581	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
879088006582	substrate binding site [chemical binding]; other site
879088006583	ligand binding site [chemical binding]; other site
879088006584	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
879088006585	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
879088006586	substrate binding site [chemical binding]; other site
879088006587	threonine dehydratase; Validated; Region: PRK08639
879088006588	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
879088006589	tetramer interface [polypeptide binding]; other site
879088006590	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088006591	catalytic residue [active]
879088006592	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
879088006593	alpha-acetolactate decarboxylase; Region: acetolac_decarb; TIGR01252
879088006594	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
879088006595	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
879088006596	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
879088006597	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
879088006598	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088006599	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088006600	DNA binding site [nucleotide binding]
879088006601	domain linker motif; other site
879088006602	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
879088006603	dimerization interface [polypeptide binding]; other site
879088006604	ligand binding site [chemical binding]; other site
879088006605	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
879088006606	intersubunit interface [polypeptide binding]; other site
879088006607	active site
879088006608	catalytic residue [active]
879088006609	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
879088006610	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
879088006611	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
879088006612	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
879088006613	active pocket/dimerization site; other site
879088006614	active site
879088006615	phosphorylation site [posttranslational modification]
879088006616	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
879088006617	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
879088006618	putative active site [active]
879088006619	SIS domain; Region: SIS; pfam01380
879088006620	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
879088006621	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
879088006622	dimer interface [polypeptide binding]; other site
879088006623	active site
879088006624	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
879088006625	dimer interface [polypeptide binding]; other site
879088006626	active site
879088006627	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
879088006628	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
879088006629	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
879088006630	active site
879088006631	phosphorylation site [posttranslational modification]
879088006632	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088006633	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088006634	DNA-binding site [nucleotide binding]; DNA binding site
879088006635	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
879088006636	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088006637	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088006638	DNA-binding site [nucleotide binding]; DNA binding site
879088006639	UTRA domain; Region: UTRA; pfam07702
879088006640	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088006641	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088006642	active site
879088006643	catalytic tetrad [active]
879088006644	acetolactate synthase; Reviewed; Region: PRK08617
879088006645	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
879088006646	PYR/PP interface [polypeptide binding]; other site
879088006647	dimer interface [polypeptide binding]; other site
879088006648	TPP binding site [chemical binding]; other site
879088006649	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
879088006650	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
879088006651	TPP-binding site [chemical binding]; other site
879088006652	dimer interface [polypeptide binding]; other site
879088006653	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088006654	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
879088006655	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
879088006656	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088006657	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088006658	dimer interface [polypeptide binding]; other site
879088006659	conserved gate region; other site
879088006660	ABC-ATPase subunit interface; other site
879088006661	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
879088006662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088006663	dimer interface [polypeptide binding]; other site
879088006664	conserved gate region; other site
879088006665	ABC-ATPase subunit interface; other site
879088006666	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
879088006667	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088006668	active site
879088006669	phosphorylation site [posttranslational modification]
879088006670	intermolecular recognition site; other site
879088006671	dimerization interface [polypeptide binding]; other site
879088006672	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088006673	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
879088006674	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
879088006675	dimerization interface [polypeptide binding]; other site
879088006676	Histidine kinase; Region: His_kinase; pfam06580
879088006677	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088006678	ATP binding site [chemical binding]; other site
879088006679	Mg2+ binding site [ion binding]; other site
879088006680	G-X-G motif; other site
879088006681	Predicted integral membrane protein [Function unknown]; Region: COG5578
879088006682	Uncharacterized conserved protein [Function unknown]; Region: COG3538
879088006683	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
879088006684	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
879088006685	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
879088006686	active site
879088006687	metal binding site [ion binding]; metal-binding site
879088006688	homodimer interface [polypeptide binding]; other site
879088006689	catalytic site [active]
879088006690	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
879088006691	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
879088006692	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
879088006693	active site
879088006694	catalytic site [active]
879088006695	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
879088006696	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
879088006697	DNA-binding site [nucleotide binding]; DNA binding site
879088006698	RNA-binding motif; other site
879088006699	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
879088006700	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
879088006701	active site
879088006702	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
879088006703	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
879088006704	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
879088006705	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
879088006706	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
879088006707	active site
879088006708	HIGH motif; other site
879088006709	nucleotide binding site [chemical binding]; other site
879088006710	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
879088006711	active site
879088006712	KMSKS motif; other site
879088006713	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
879088006714	tRNA binding surface [nucleotide binding]; other site
879088006715	anticodon binding site; other site
879088006716	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
879088006717	DivIVA protein; Region: DivIVA; pfam05103
879088006718	DivIVA domain; Region: DivI1A_domain; TIGR03544
879088006719	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
879088006720	HTH domain; Region: HTH_11; pfam08279
879088006721	3H domain; Region: 3H; pfam02829
879088006722	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
879088006723	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
879088006724	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088006725	catalytic residue [active]
879088006726	L-aspartate oxidase; Provisional; Region: PRK08071
879088006727	L-aspartate oxidase; Provisional; Region: PRK06175
879088006728	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
879088006729	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK08072
879088006730	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
879088006731	dimerization interface [polypeptide binding]; other site
879088006732	active site
879088006733	quinolinate synthetase; Provisional; Region: PRK09375
879088006734	Transposase; Region: HTH_Tnp_1; cl17663
879088006735	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006736	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006737	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088006738	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006739	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006740	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006741	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006742	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006743	Leucine rich repeat; Region: LRR_8; pfam13855
879088006744	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088006745	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088006746	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006747	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006748	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006749	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
879088006750	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006751	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006752	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006753	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
879088006754	Listeria-Bacteroides repeat domain (List_Bact_rpt); Region: Flg_new; pfam09479
879088006755	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088006756	Methyltransferase domain; Region: Methyltransf_31; pfam13847
879088006757	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088006758	S-adenosylmethionine binding site [chemical binding]; other site
879088006759	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088006760	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088006761	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
879088006762	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088006763	RNA binding surface [nucleotide binding]; other site
879088006764	YGGT family; Region: YGGT; pfam02325
879088006765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
879088006766	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
879088006767	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
879088006768	catalytic residue [active]
879088006769	cell division protein FtsZ; Validated; Region: PRK09330
879088006770	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
879088006771	nucleotide binding site [chemical binding]; other site
879088006772	SulA interaction site; other site
879088006773	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
879088006774	Cell division protein FtsA; Region: FtsA; smart00842
879088006775	Cell division protein FtsA; Region: FtsA; pfam14450
879088006776	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
879088006777	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
879088006778	Cell division protein FtsQ; Region: FtsQ; pfam03799
879088006779	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
879088006780	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
879088006781	active site
879088006782	homodimer interface [polypeptide binding]; other site
879088006783	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
879088006784	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
879088006785	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
879088006786	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
879088006787	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
879088006788	Mg++ binding site [ion binding]; other site
879088006789	putative catalytic motif [active]
879088006790	putative substrate binding site [chemical binding]; other site
879088006791	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
879088006792	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
879088006793	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
879088006794	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
879088006795	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
879088006796	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
879088006797	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
879088006798	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
879088006799	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
879088006800	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
879088006801	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
879088006802	MraW methylase family; Region: Methyltransf_5; pfam01795
879088006803	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
879088006804	MraZ protein; Region: MraZ; pfam02381
879088006805	MraZ protein; Region: MraZ; pfam02381
879088006806	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088006807	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088006808	putative substrate translocation pore; other site
879088006809	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
879088006810	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
879088006811	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
879088006812	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
879088006813	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
879088006814	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
879088006815	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
879088006816	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
879088006817	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; pfam05636
879088006818	hypothetical protein; Provisional; Region: PRK13670
879088006819	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
879088006820	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
879088006821	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
879088006822	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088006823	Walker A/P-loop; other site
879088006824	ATP binding site [chemical binding]; other site
879088006825	Q-loop/lid; other site
879088006826	ABC transporter signature motif; other site
879088006827	Walker B; other site
879088006828	D-loop; other site
879088006829	H-loop/switch region; other site
879088006830	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
879088006831	PDZ domain of ATP-dependent LON serine proteases. Most PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. In this bacterial subfamily of protease-associated PDZ...; Region: PDZ_LON_protease; cd00986
879088006832	protein binding site [polypeptide binding]; other site
879088006833	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
879088006834	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
879088006835	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
879088006836	active site
879088006837	(T/H)XGH motif; other site
879088006838	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
879088006839	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088006840	S-adenosylmethionine binding site [chemical binding]; other site
879088006841	hypothetical protein; Provisional; Region: PRK02886
879088006842	Regulatory protein involved in competence development and sporulation [Replication, recombination and repair;    Signal transduction mechanisms]; Region: COG3679
879088006843	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
879088006844	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
879088006845	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
879088006846	UbiA prenyltransferase family; Region: UbiA; pfam01040
879088006847	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
879088006848	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
879088006849	Ion transport protein; Region: Ion_trans; pfam00520
879088006850	Ion channel; Region: Ion_trans_2; pfam07885
879088006851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
879088006852	MOSC domain; Region: MOSC; pfam03473
879088006853	3-alpha domain; Region: 3-alpha; pfam03475
879088006854	Reeler-like domain of YcnI and similar proteins; Region: YcnI_like; cd08545
879088006855	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
879088006856	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
879088006857	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13953
879088006858	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
879088006859	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
879088006860	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
879088006861	active site
879088006862	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
879088006863	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
879088006864	ring oligomerisation interface [polypeptide binding]; other site
879088006865	ATP/Mg binding site [chemical binding]; other site
879088006866	stacking interactions; other site
879088006867	hinge regions; other site
879088006868	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
879088006869	oligomerisation interface [polypeptide binding]; other site
879088006870	mobile loop; other site
879088006871	roof hairpin; other site
879088006872	CAAX protease self-immunity; Region: Abi; pfam02517
879088006873	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
879088006874	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
879088006875	CoA binding domain; Region: CoA_binding; pfam02629
879088006876	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
879088006877	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088006878	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088006879	ABC transporter; Region: ABC_tran_2; pfam12848
879088006880	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088006881	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088006882	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
879088006883	UGMP family protein; Validated; Region: PRK09604
879088006884	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
879088006885	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
879088006886	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088006887	Coenzyme A binding pocket [chemical binding]; other site
879088006888	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
879088006889	Glycoprotease family; Region: Peptidase_M22; pfam00814
879088006890	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
879088006891	camphor resistance protein CrcB; Provisional; Region: PRK14214
879088006892	camphor resistance protein CrcB; Provisional; Region: PRK14231
879088006893	Uncharacterized conserved protein [Function unknown]; Region: COG4832
879088006894	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
879088006895	Phosphotransferase enzyme family; Region: APH; pfam01636
879088006896	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
879088006897	active site
879088006898	ATP binding site [chemical binding]; other site
879088006899	Cna protein B-type domain; Region: Cna_B; pfam05738
879088006900	Cna protein B-type domain; Region: Cna_B; pfam05738
879088006901	Cna protein B-type domain; Region: Cna_B; pfam05738
879088006902	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088006903	non-specific DNA binding site [nucleotide binding]; other site
879088006904	salt bridge; other site
879088006905	sequence-specific DNA binding site [nucleotide binding]; other site
879088006906	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
879088006907	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
879088006908	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088006909	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088006910	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
879088006911	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
879088006912	substrate binding pocket [chemical binding]; other site
879088006913	argininosuccinate synthase; Provisional; Region: PRK13820
879088006914	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
879088006915	ANP binding site [chemical binding]; other site
879088006916	Substrate Binding Site II [chemical binding]; other site
879088006917	Substrate Binding Site I [chemical binding]; other site
879088006918	argininosuccinate lyase; Provisional; Region: PRK00855
879088006919	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
879088006920	active sites [active]
879088006921	tetramer interface [polypeptide binding]; other site
879088006922	BCCT family transporter; Region: BCCT; pfam02028
879088006923	hypothetical protein; Provisional; Region: PRK06357
879088006924	active site
879088006925	intersubunit interface [polypeptide binding]; other site
879088006926	Zn2+ binding site [ion binding]; other site
879088006927	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
879088006928	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
879088006929	putative substrate binding site [chemical binding]; other site
879088006930	putative ATP binding site [chemical binding]; other site
879088006931	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
879088006932	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
879088006933	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
879088006934	active site
879088006935	P-loop; other site
879088006936	phosphorylation site [posttranslational modification]
879088006937	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088006938	active site
879088006939	phosphorylation site [posttranslational modification]
879088006940	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088006941	PRD domain; Region: PRD; pfam00874
879088006942	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088006943	active site
879088006944	P-loop; other site
879088006945	phosphorylation site [posttranslational modification]
879088006946	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: PtsN; COG1762
879088006947	active site
879088006948	phosphorylation site [posttranslational modification]
879088006949	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
879088006950	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088006951	DNA-binding site [nucleotide binding]; DNA binding site
879088006952	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088006953	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088006954	homodimer interface [polypeptide binding]; other site
879088006955	catalytic residue [active]
879088006956	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
879088006957	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
879088006958	active site
879088006959	multimer interface [polypeptide binding]; other site
879088006960	glutamine amidotransferase subunit PdxT; Provisional; Region: PRK13525
879088006961	conserved cys residue [active]
879088006962	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
879088006963	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
879088006964	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
879088006965	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
879088006966	G1 box; other site
879088006967	GTP/Mg2+ binding site [chemical binding]; other site
879088006968	Switch I region; other site
879088006969	G2 box; other site
879088006970	G3 box; other site
879088006971	Switch II region; other site
879088006972	G4 box; other site
879088006973	G5 box; other site
879088006974	Nucleoside recognition; Region: Gate; pfam07670
879088006975	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
879088006976	Nucleoside recognition; Region: Gate; pfam07670
879088006977	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
879088006978	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
879088006979	putative active site [active]
879088006980	putative metal binding site [ion binding]; other site
879088006981	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088006982	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
879088006983	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088006984	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
879088006985	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
879088006986	active site
879088006987	dimer interface [polypeptide binding]; other site
879088006988	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
879088006989	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
879088006990	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
879088006991	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
879088006992	dimer interface [polypeptide binding]; other site
879088006993	FMN binding site [chemical binding]; other site
879088006994	NADPH bind site [chemical binding]; other site
879088006995	Helix-turn-helix domain; Region: HTH_17; pfam12728
879088006996	putative heme peroxidase; Provisional; Region: PRK12276
879088006997	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088006998	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088006999	Walker A/P-loop; other site
879088007000	ATP binding site [chemical binding]; other site
879088007001	Q-loop/lid; other site
879088007002	ABC transporter signature motif; other site
879088007003	Walker B; other site
879088007004	D-loop; other site
879088007005	H-loop/switch region; other site
879088007006	FtsX-like permease family; Region: FtsX; pfam02687
879088007007	FtsX-like permease family; Region: FtsX; pfam02687
879088007008	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088007009	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088007010	Coenzyme A binding pocket [chemical binding]; other site
879088007011	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
879088007012	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
879088007013	active site
879088007014	substrate binding site [chemical binding]; other site
879088007015	metal binding site [ion binding]; metal-binding site
879088007016	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
879088007017	YbbR-like protein; Region: YbbR; pfam07949
879088007018	YbbR-like protein; Region: YbbR; pfam07949
879088007019	YbbR-like protein; Region: YbbR; pfam07949
879088007020	Uncharacterized conserved protein [Function unknown]; Region: COG1624
879088007021	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
879088007022	maltose phosphorylase; Provisional; Region: PRK13807
879088007023	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
879088007024	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
879088007025	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
879088007026	Predicted integral membrane protein [Function unknown]; Region: COG5521
879088007027	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088007028	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007029	dimer interface [polypeptide binding]; other site
879088007030	conserved gate region; other site
879088007031	putative PBP binding loops; other site
879088007032	ABC-ATPase subunit interface; other site
879088007033	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007034	dimer interface [polypeptide binding]; other site
879088007035	conserved gate region; other site
879088007036	putative PBP binding loops; other site
879088007037	ABC-ATPase subunit interface; other site
879088007038	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
879088007039	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088007040	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
879088007041	homodimer interface [polypeptide binding]; other site
879088007042	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
879088007043	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
879088007044	active site
879088007045	homodimer interface [polypeptide binding]; other site
879088007046	catalytic site [active]
879088007047	CAAX protease self-immunity; Region: Abi; cl00558
879088007048	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088007049	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088007050	DNA binding site [nucleotide binding]
879088007051	domain linker motif; other site
879088007052	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
879088007053	ligand binding site [chemical binding]; other site
879088007054	dimerization interface [polypeptide binding]; other site
879088007055	Amino acid permease; Region: AA_permease_2; pfam13520
879088007056	K+ potassium transporter; Region: K_trans; cl15781
879088007057	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088007058	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088007059	ligand binding site [chemical binding]; other site
879088007060	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088007061	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088007062	ligand binding site [chemical binding]; other site
879088007063	flexible hinge region; other site
879088007064	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088007065	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
879088007066	intersubunit interface [polypeptide binding]; other site
879088007067	active site
879088007068	zinc binding site [ion binding]; other site
879088007069	Na+ binding site [ion binding]; other site
879088007070	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
879088007071	intersubunit interface [polypeptide binding]; other site
879088007072	active site
879088007073	zinc binding site [ion binding]; other site
879088007074	Na+ binding site [ion binding]; other site
879088007075	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088007076	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088007077	active site
879088007078	P-loop; other site
879088007079	phosphorylation site [posttranslational modification]
879088007080	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088007081	active site
879088007082	phosphorylation site [posttranslational modification]
879088007083	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088007084	HTH domain; Region: HTH_11; pfam08279
879088007085	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088007086	PRD domain; Region: PRD; pfam00874
879088007087	PRD domain; Region: PRD; pfam00874
879088007088	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088007089	active site
879088007090	P-loop; other site
879088007091	phosphorylation site [posttranslational modification]
879088007092	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
879088007093	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088007094	Walker A/P-loop; other site
879088007095	ATP binding site [chemical binding]; other site
879088007096	Q-loop/lid; other site
879088007097	ABC transporter signature motif; other site
879088007098	Walker B; other site
879088007099	D-loop; other site
879088007100	H-loop/switch region; other site
879088007101	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
879088007102	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
879088007103	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
879088007104	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088007105	Coenzyme A binding pocket [chemical binding]; other site
879088007106	Transcriptional regulators [Transcription]; Region: GntR; COG1802
879088007107	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
879088007108	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
879088007109	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
879088007110	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088007111	DNA-binding site [nucleotide binding]; DNA binding site
879088007112	UTRA domain; Region: UTRA; pfam07702
879088007113	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
879088007114	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
879088007115	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088007116	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088007117	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
879088007118	putative dimerization interface [polypeptide binding]; other site
879088007119	Predicted membrane protein [Function unknown]; Region: COG2855
879088007120	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
879088007121	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
879088007122	putative metal binding site [ion binding]; other site
879088007123	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
879088007124	homodimer interface [polypeptide binding]; other site
879088007125	chemical substrate binding site [chemical binding]; other site
879088007126	oligomer interface [polypeptide binding]; other site
879088007127	metal binding site [ion binding]; metal-binding site
879088007128	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088007129	catalytic residues [active]
879088007130	flavodoxin; Provisional; Region: PRK09271
879088007131	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
879088007132	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
879088007133	dimer interface [polypeptide binding]; other site
879088007134	putative radical transfer pathway; other site
879088007135	diiron center [ion binding]; other site
879088007136	tyrosyl radical; other site
879088007137	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09209
879088007138	Class I ribonucleotide reductase; Region: RNR_I; cd01679
879088007139	active site
879088007140	dimer interface [polypeptide binding]; other site
879088007141	catalytic residues [active]
879088007142	effector binding site; other site
879088007143	R2 peptide binding site; other site
879088007144	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
879088007145	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
879088007146	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
879088007147	SCP-2 sterol transfer family; Region: SCP2; cl01225
879088007148	CsbD-like; Region: CsbD; cl17424
879088007149	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088007150	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088007151	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
879088007152	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
879088007153	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
879088007154	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
879088007155	conserved cys residue [active]
879088007156	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
879088007157	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088007158	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088007159	Cupin; Region: Cupin_1; pfam00190
879088007160	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088007161	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088007162	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088007163	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088007164	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088007165	ligand binding site [chemical binding]; other site
879088007166	flexible hinge region; other site
879088007167	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
879088007168	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
879088007169	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088007170	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
879088007171	dimer interface [polypeptide binding]; other site
879088007172	active site
879088007173	metal binding site [ion binding]; metal-binding site
879088007174	glutathione binding site [chemical binding]; other site
879088007175	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
879088007176	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
879088007177	FMN binding site [chemical binding]; other site
879088007178	substrate binding site [chemical binding]; other site
879088007179	putative catalytic residue [active]
879088007180	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
879088007181	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
879088007182	Coenzyme A transferase; Region: CoA_trans; smart00882
879088007183	Coenzyme A transferase; Region: CoA_trans; cl17247
879088007184	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088007185	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
879088007186	Walker A motif; other site
879088007187	ATP binding site [chemical binding]; other site
879088007188	Walker B motif; other site
879088007189	arginine finger; other site
879088007190	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
879088007191	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
879088007192	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
879088007193	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
879088007194	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
879088007195	metal binding site [ion binding]; metal-binding site
879088007196	active site
879088007197	I-site; other site
879088007198	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
879088007199	classical (c) SDRs; Region: SDR_c; cd05233
879088007200	NAD(P) binding site [chemical binding]; other site
879088007201	active site
879088007202	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
879088007203	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088007204	Tic20-like protein; Region: Tic20; pfam09685
879088007205	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
879088007206	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007207	Collagen binding domain; Region: Collagen_bind; pfam05737
879088007208	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007209	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007210	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007211	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007212	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007213	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
879088007214	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007215	Collagen binding domain; Region: Collagen_bind; pfam05737
879088007216	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007217	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007218	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007219	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007220	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007221	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007222	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007223	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088007224	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007225	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007226	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088007227	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
879088007228	Sortase B (SrtB) or subfamily-2 sortases are membrane cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_B_2; cd05826
879088007229	active site
879088007230	catalytic site [active]
879088007231	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
879088007232	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
879088007233	Walker A/P-loop; other site
879088007234	ATP binding site [chemical binding]; other site
879088007235	Q-loop/lid; other site
879088007236	ABC transporter signature motif; other site
879088007237	Walker B; other site
879088007238	D-loop; other site
879088007239	H-loop/switch region; other site
879088007240	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
879088007241	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088007242	ABC-ATPase subunit  interface; other site
879088007243	dimer interface [polypeptide binding]; other site
879088007244	putative PBP binding regions; other site
879088007245	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
879088007246	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
879088007247	intersubunit interface [polypeptide binding]; other site
879088007248	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
879088007249	heme-binding site [chemical binding]; other site
879088007250	Cell surface protein [Cell envelope biogenesis, outer membrane]; Region: COG5386
879088007251	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
879088007252	heme-binding site [chemical binding]; other site
879088007253	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
879088007254	heme-binding site [chemical binding]; other site
879088007255	sortase B cell surface sorting signal; Region: srtB_target; TIGR03063
879088007256	heme uptake protein IsdC; Region: IsdC; TIGR03656
879088007257	NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920
879088007258	heme-binding site [chemical binding]; other site
879088007259	sortase B cell surface sorting signal; Region: srtB_target; TIGR03063
879088007260	Protein of unknown function (DUF3116); Region: DUF3116; pfam11313
879088007261	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
879088007262	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
879088007263	active site
879088007264	Zn binding site [ion binding]; other site
879088007265	Competence protein CoiA-like family; Region: CoiA; cl11541
879088007266	Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion]; Region: MecA; COG4862
879088007267	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
879088007268	ArsC family; Region: ArsC; pfam03960
879088007269	putative catalytic residues [active]
879088007270	thiol/disulfide switch; other site
879088007271	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
879088007272	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
879088007273	Walker A/P-loop; other site
879088007274	ATP binding site [chemical binding]; other site
879088007275	Q-loop/lid; other site
879088007276	ABC transporter signature motif; other site
879088007277	Walker B; other site
879088007278	D-loop; other site
879088007279	H-loop/switch region; other site
879088007280	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
879088007281	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
879088007282	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
879088007283	Walker A/P-loop; other site
879088007284	ATP binding site [chemical binding]; other site
879088007285	Q-loop/lid; other site
879088007286	ABC transporter signature motif; other site
879088007287	Walker B; other site
879088007288	D-loop; other site
879088007289	H-loop/switch region; other site
879088007290	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
879088007291	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
879088007292	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007293	dimer interface [polypeptide binding]; other site
879088007294	conserved gate region; other site
879088007295	putative PBP binding loops; other site
879088007296	ABC-ATPase subunit interface; other site
879088007297	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
879088007298	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007299	dimer interface [polypeptide binding]; other site
879088007300	conserved gate region; other site
879088007301	putative PBP binding loops; other site
879088007302	ABC-ATPase subunit interface; other site
879088007303	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
879088007304	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
879088007305	peptide binding site [polypeptide binding]; other site
879088007306	Domain of unknown function (DUF3899); Region: DUF3899; pfam13038
879088007307	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
879088007308	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
879088007309	active site
879088007310	HIGH motif; other site
879088007311	dimer interface [polypeptide binding]; other site
879088007312	KMSKS motif; other site
879088007313	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
879088007314	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088007315	MarR family; Region: MarR; pfam01047
879088007316	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
879088007317	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
879088007318	dimer interface [polypeptide binding]; other site
879088007319	active site
879088007320	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
879088007321	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
879088007322	dimer interface [polypeptide binding]; other site
879088007323	active site
879088007324	CoA binding pocket [chemical binding]; other site
879088007325	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088007326	SH3-like domain; Region: SH3_8; pfam13457
879088007327	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
879088007328	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088007329	catalytic core [active]
879088007330	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
879088007331	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
879088007332	Clp amino terminal domain; Region: Clp_N; pfam02861
879088007333	Clp amino terminal domain; Region: Clp_N; pfam02861
879088007334	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088007335	Walker A motif; other site
879088007336	ATP binding site [chemical binding]; other site
879088007337	Walker B motif; other site
879088007338	arginine finger; other site
879088007339	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088007340	Walker A motif; other site
879088007341	ATP binding site [chemical binding]; other site
879088007342	Walker B motif; other site
879088007343	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
879088007344	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
879088007345	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
879088007346	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088007347	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088007348	active site
879088007349	motif I; other site
879088007350	motif II; other site
879088007351	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
879088007352	Predicted acetyltransferase [General function prediction only]; Region: COG3393
879088007353	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
879088007354	ferrochelatase; Provisional; Region: PRK12435
879088007355	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
879088007356	C-terminal domain interface [polypeptide binding]; other site
879088007357	active site
879088007358	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
879088007359	active site
879088007360	N-terminal domain interface [polypeptide binding]; other site
879088007361	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
879088007362	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
879088007363	substrate binding site [chemical binding]; other site
879088007364	active site
879088007365	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
879088007366	Predicted ABC-type exoprotein transport system, permease component [Intracellular trafficking and secretion]; Region: EcsB; COG4473
879088007367	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
879088007368	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088007369	Walker A/P-loop; other site
879088007370	ATP binding site [chemical binding]; other site
879088007371	Q-loop/lid; other site
879088007372	ABC transporter signature motif; other site
879088007373	Walker B; other site
879088007374	D-loop; other site
879088007375	H-loop/switch region; other site
879088007376	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
879088007377	HIT family signature motif; other site
879088007378	catalytic residue [active]
879088007379	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
879088007380	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
879088007381	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
879088007382	SurA N-terminal domain; Region: SurA_N_3; cl07813
879088007383	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
879088007384	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
879088007385	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
879088007386	generic binding surface II; other site
879088007387	generic binding surface I; other site
879088007388	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088007389	Zn2+ binding site [ion binding]; other site
879088007390	Mg2+ binding site [ion binding]; other site
879088007391	Uncharacterized conserved protein [Function unknown]; Region: COG4717
879088007392	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
879088007393	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
879088007394	active site
879088007395	metal binding site [ion binding]; metal-binding site
879088007396	DNA binding site [nucleotide binding]
879088007397	hypothetical protein; Provisional; Region: PRK13676
879088007398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
879088007399	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
879088007400	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
879088007401	Int/Topo IB signature motif; other site
879088007402	Helix-turn-helix domain; Region: HTH_16; pfam12645
879088007403	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
879088007404	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
879088007405	DNA binding residues [nucleotide binding]
879088007406	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
879088007407	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
879088007408	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
879088007409	P loop; other site
879088007410	Nucleotide binding site [chemical binding]; other site
879088007411	DTAP/Switch II; other site
879088007412	Switch I; other site
879088007413	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
879088007414	DTAP/Switch II; other site
879088007415	Switch I; other site
879088007416	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088007417	dimerization interface [polypeptide binding]; other site
879088007418	putative DNA binding site [nucleotide binding]; other site
879088007419	putative Zn2+ binding site [ion binding]; other site
879088007420	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
879088007421	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088007422	dimerization interface [polypeptide binding]; other site
879088007423	putative DNA binding site [nucleotide binding]; other site
879088007424	putative Zn2+ binding site [ion binding]; other site
879088007425	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
879088007426	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
879088007427	P loop; other site
879088007428	Nucleotide binding site [chemical binding]; other site
879088007429	DTAP/Switch II; other site
879088007430	Switch I; other site
879088007431	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
879088007432	DTAP/Switch II; other site
879088007433	Switch I; other site
879088007434	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
879088007435	arsenical-resistance protein; Region: acr3; TIGR00832
879088007436	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
879088007437	arsenical-resistance protein; Region: acr3; TIGR00832
879088007438	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088007439	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
879088007440	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088007441	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
879088007442	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
879088007443	active site residue [active]
879088007444	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088007445	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088007446	Walker A/P-loop; other site
879088007447	ATP binding site [chemical binding]; other site
879088007448	Q-loop/lid; other site
879088007449	ABC transporter signature motif; other site
879088007450	Walker B; other site
879088007451	D-loop; other site
879088007452	H-loop/switch region; other site
879088007453	inner membrane transport permease; Provisional; Region: PRK15066
879088007454	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
879088007455	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088007456	putative DNA binding site [nucleotide binding]; other site
879088007457	dimerization interface [polypeptide binding]; other site
879088007458	putative Zn2+ binding site [ion binding]; other site
879088007459	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
879088007460	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
879088007461	metal-binding site [ion binding]
879088007462	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088007463	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
879088007464	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
879088007465	N-acetyl-D-glucosamine binding site [chemical binding]; other site
879088007466	catalytic residue [active]
879088007467	TIGR02594 family protein; Region: TIGR02594
879088007468	AAA-like domain; Region: AAA_10; pfam12846
879088007469	TcpE family; Region: TcpE; pfam12648
879088007470	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
879088007471	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
879088007472	Antirestriction protein (ArdA); Region: ArdA; cl01953
879088007473	Replication initiation factor; Region: Rep_trans; pfam02486
879088007474	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
879088007475	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
879088007476	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
879088007477	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007478	Cna protein B-type domain; Region: Cna_B; pfam05738
879088007479	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
879088007480	TIGR03545 family protein; Region: TIGR03545
879088007481	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
879088007482	fumarate hydratase; Reviewed; Region: fumC; PRK00485
879088007483	Class II fumarases; Region: Fumarase_classII; cd01362
879088007484	active site
879088007485	tetramer interface [polypeptide binding]; other site
879088007486	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
879088007487	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088007488	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088007489	Walker A/P-loop; other site
879088007490	ATP binding site [chemical binding]; other site
879088007491	Q-loop/lid; other site
879088007492	ABC transporter signature motif; other site
879088007493	Walker B; other site
879088007494	D-loop; other site
879088007495	H-loop/switch region; other site
879088007496	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
879088007497	Transglycosylase; Region: Transgly; pfam00912
879088007498	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
879088007499	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
879088007500	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
879088007501	Low molecular weight phosphatase family; Region: LMWPc; cl00105
879088007502	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
879088007503	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
879088007504	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
879088007505	Domain of unknown function DUF21; Region: DUF21; pfam01595
879088007506	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
879088007507	Transporter associated domain; Region: CorC_HlyC; smart01091
879088007508	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088007509	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088007510	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
879088007511	putative dimerization interface [polypeptide binding]; other site
879088007512	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
879088007513	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
879088007514	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
879088007515	active site
879088007516	FMN binding site [chemical binding]; other site
879088007517	substrate binding site [chemical binding]; other site
879088007518	putative catalytic residue [active]
879088007519	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088007520	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088007521	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
879088007522	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
879088007523	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
879088007524	shikimate binding site; other site
879088007525	NAD(P) binding site [chemical binding]; other site
879088007526	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088007527	putative substrate translocation pore; other site
879088007528	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088007529	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088007530	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088007531	putative substrate translocation pore; other site
879088007532	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
879088007533	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088007534	Walker A/P-loop; other site
879088007535	ATP binding site [chemical binding]; other site
879088007536	Q-loop/lid; other site
879088007537	ABC transporter signature motif; other site
879088007538	Walker B; other site
879088007539	D-loop; other site
879088007540	H-loop/switch region; other site
879088007541	Predicted transcriptional regulators [Transcription]; Region: COG1725
879088007542	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
879088007543	DNA-binding site [nucleotide binding]; DNA binding site
879088007544	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
879088007545	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
879088007546	DNA binding site [nucleotide binding]
879088007547	active site
879088007548	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
879088007549	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
879088007550	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088007551	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088007552	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
879088007553	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
879088007554	active site
879088007555	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_6; cd07242
879088007556	putative dimer interface [polypeptide binding]; other site
879088007557	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088007558	ligand binding site [chemical binding]; other site
879088007559	Zn binding site [ion binding]; other site
879088007560	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
879088007561	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
879088007562	active site
879088007563	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088007564	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088007565	active site
879088007566	catalytic tetrad [active]
879088007567	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
879088007568	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
879088007569	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
879088007570	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
879088007571	substrate binding pocket [chemical binding]; other site
879088007572	membrane-bound complex binding site; other site
879088007573	hinge residues; other site
879088007574	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
879088007575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007576	dimer interface [polypeptide binding]; other site
879088007577	conserved gate region; other site
879088007578	putative PBP binding loops; other site
879088007579	ABC-ATPase subunit interface; other site
879088007580	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
879088007581	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
879088007582	Walker A/P-loop; other site
879088007583	ATP binding site [chemical binding]; other site
879088007584	Q-loop/lid; other site
879088007585	ABC transporter signature motif; other site
879088007586	Walker B; other site
879088007587	D-loop; other site
879088007588	H-loop/switch region; other site
879088007589	aspartate aminotransferase; Provisional; Region: PRK06348
879088007590	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088007591	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088007592	homodimer interface [polypeptide binding]; other site
879088007593	catalytic residue [active]
879088007594	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
879088007595	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
879088007596	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088007597	motif II; other site
879088007598	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
879088007599	intracellular protease, PfpI family; Region: PfpI; TIGR01382
879088007600	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
879088007601	proposed catalytic triad [active]
879088007602	conserved cys residue [active]
879088007603	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088007604	methionine cluster; other site
879088007605	active site
879088007606	phosphorylation site [posttranslational modification]
879088007607	metal binding site [ion binding]; metal-binding site
879088007608	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088007609	Coenzyme A binding pocket [chemical binding]; other site
879088007610	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088007611	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
879088007612	esterase; Provisional; Region: PRK10566
879088007613	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
879088007614	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088007615	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
879088007616	motif II; other site
879088007617	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088007618	Uncharacterized conserved protein [Function unknown]; Region: COG1284
879088007619	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088007620	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088007621	hypothetical protein; Provisional; Region: PRK13673
879088007622	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
879088007623	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
879088007624	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
879088007625	Part of AAA domain; Region: AAA_19; pfam13245
879088007626	Family description; Region: UvrD_C_2; pfam13538
879088007627	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
879088007628	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
879088007629	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
879088007630	IDEAL domain; Region: IDEAL; pfam08858
879088007631	ComK protein; Region: ComK; cl11560
879088007632	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
879088007633	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088007634	non-specific DNA binding site [nucleotide binding]; other site
879088007635	salt bridge; other site
879088007636	sequence-specific DNA binding site [nucleotide binding]; other site
879088007637	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
879088007638	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088007639	active site
879088007640	phosphorylation site [posttranslational modification]
879088007641	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088007642	active site
879088007643	P-loop; other site
879088007644	phosphorylation site [posttranslational modification]
879088007645	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088007646	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
879088007647	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
879088007648	putative substrate binding site [chemical binding]; other site
879088007649	putative ATP binding site [chemical binding]; other site
879088007650	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088007651	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
879088007652	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088007653	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
879088007654	trimer interface [polypeptide binding]; other site
879088007655	active site
879088007656	G bulge; other site
879088007657	Uncharacterized conserved protein [Function unknown]; Region: COG1683
879088007658	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
879088007659	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
879088007660	non-specific DNA interactions [nucleotide binding]; other site
879088007661	DNA binding site [nucleotide binding]
879088007662	sequence specific DNA binding site [nucleotide binding]; other site
879088007663	putative cAMP binding site [chemical binding]; other site
879088007664	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
879088007665	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
879088007666	substrate binding site [chemical binding]; other site
879088007667	ATP binding site [chemical binding]; other site
879088007668	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
879088007669	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
879088007670	RNA binding surface [nucleotide binding]; other site
879088007671	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
879088007672	active site
879088007673	uracil binding [chemical binding]; other site
879088007674	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
879088007675	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
879088007676	active site
879088007677	non-prolyl cis peptide bond; other site
879088007678	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
879088007679	catalytic residues [active]
879088007680	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
879088007681	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
879088007682	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
879088007683	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
879088007684	Walker A/P-loop; other site
879088007685	ATP binding site [chemical binding]; other site
879088007686	Q-loop/lid; other site
879088007687	ABC transporter signature motif; other site
879088007688	Walker B; other site
879088007689	D-loop; other site
879088007690	H-loop/switch region; other site
879088007691	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007692	putative PBP binding loops; other site
879088007693	dimer interface [polypeptide binding]; other site
879088007694	ABC-ATPase subunit interface; other site
879088007695	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
879088007696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007697	dimer interface [polypeptide binding]; other site
879088007698	conserved gate region; other site
879088007699	putative PBP binding loops; other site
879088007700	ABC-ATPase subunit interface; other site
879088007701	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
879088007702	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
879088007703	substrate binding pocket [chemical binding]; other site
879088007704	membrane-bound complex binding site; other site
879088007705	hinge residues; other site
879088007706	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088007707	Coenzyme A binding pocket [chemical binding]; other site
879088007708	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
879088007709	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
879088007710	Transcriptional regulator [Transcription]; Region: LysR; COG0583
879088007711	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
879088007712	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
879088007713	dimerization interface [polypeptide binding]; other site
879088007714	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
879088007715	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
879088007716	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
879088007717	active site
879088007718	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088007719	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088007720	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088007721	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
879088007722	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
879088007723	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
879088007724	active site
879088007725	trimer interface [polypeptide binding]; other site
879088007726	allosteric site; other site
879088007727	active site lid [active]
879088007728	hexamer (dimer of trimers) interface [polypeptide binding]; other site
879088007729	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088007730	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
879088007731	Predicted membrane protein [Function unknown]; Region: COG1511
879088007732	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
879088007733	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
879088007734	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
879088007735	Predicted transcriptional regulator [Transcription]; Region: COG1959
879088007736	Transcriptional regulator; Region: Rrf2; pfam02082
879088007737	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
879088007738	L-tyrosine decarboxylase; Provisional; Region: PRK13520
879088007739	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
879088007740	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088007741	catalytic residue [active]
879088007742	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
879088007743	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088007744	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
879088007745	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
879088007746	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
879088007747	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
879088007748	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
879088007749	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
879088007750	active site
879088007751	dimer interface [polypeptide binding]; other site
879088007752	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
879088007753	dimer interface [polypeptide binding]; other site
879088007754	active site
879088007755	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
879088007756	nudix motif; other site
879088007757	general stress protein 13; Validated; Region: PRK08059
879088007758	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
879088007759	RNA binding site [nucleotide binding]; other site
879088007760	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
879088007761	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
879088007762	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088007763	homodimer interface [polypeptide binding]; other site
879088007764	catalytic residue [active]
879088007765	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
879088007766	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088007767	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088007768	Walker A/P-loop; other site
879088007769	ATP binding site [chemical binding]; other site
879088007770	Q-loop/lid; other site
879088007771	ABC transporter signature motif; other site
879088007772	Walker B; other site
879088007773	D-loop; other site
879088007774	H-loop/switch region; other site
879088007775	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088007776	active site
879088007777	P-loop; other site
879088007778	phosphorylation site [posttranslational modification]
879088007779	aspartate kinase; Reviewed; Region: PRK09034
879088007780	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
879088007781	putative catalytic residues [active]
879088007782	putative nucleotide binding site [chemical binding]; other site
879088007783	putative aspartate binding site [chemical binding]; other site
879088007784	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
879088007785	allosteric regulatory residue; other site
879088007786	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
879088007787	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
879088007788	putative active site [active]
879088007789	putative NTP binding site [chemical binding]; other site
879088007790	putative nucleic acid binding site [nucleotide binding]; other site
879088007791	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
879088007792	active site
879088007793	drug efflux system protein MdtG; Provisional; Region: PRK09874
879088007794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088007795	putative substrate translocation pore; other site
879088007796	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
879088007797	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
879088007798	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
879088007799	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12573
879088007800	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08600
879088007801	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07691
879088007802	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
879088007803	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
879088007804	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12600
879088007805	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12585
879088007806	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
879088007807	CoenzymeA binding site [chemical binding]; other site
879088007808	subunit interaction site [polypeptide binding]; other site
879088007809	PHB binding site; other site
879088007810	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1963
879088007811	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
879088007812	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
879088007813	Cl- selectivity filter; other site
879088007814	Cl- binding residues [ion binding]; other site
879088007815	pore gating glutamate residue; other site
879088007816	dimer interface [polypeptide binding]; other site
879088007817	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088007818	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3878
879088007819	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
879088007820	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088007821	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
879088007822	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088007823	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088007824	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
879088007825	NADH(P)-binding; Region: NAD_binding_10; pfam13460
879088007826	NAD(P) binding site [chemical binding]; other site
879088007827	putative active site [active]
879088007828	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4844
879088007829	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4837
879088007830	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088007831	Leucine-rich repeats; other site
879088007832	Substrate binding site [chemical binding]; other site
879088007833	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088007834	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088007835	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088007836	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007837	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007838	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007839	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088007840	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
879088007841	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
879088007842	tetramer interfaces [polypeptide binding]; other site
879088007843	binuclear metal-binding site [ion binding]; other site
879088007844	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
879088007845	Domain of unknown function DUF21; Region: DUF21; pfam01595
879088007846	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
879088007847	Transporter associated domain; Region: CorC_HlyC; smart01091
879088007848	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
879088007849	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088007850	Coenzyme A binding pocket [chemical binding]; other site
879088007851	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
879088007852	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088007853	active site
879088007854	motif I; other site
879088007855	motif II; other site
879088007856	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088007857	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4470
879088007858	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
879088007859	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
879088007860	active site
879088007861	metal binding site [ion binding]; metal-binding site
879088007862	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
879088007863	Predicted permeases [General function prediction only]; Region: COG0730
879088007864	Predicted membrane protein [Function unknown]; Region: COG4272
879088007865	Uncharacterized conserved protein [Function unknown]; Region: COG1801
879088007866	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
879088007867	FeS assembly protein SufB; Region: sufB; TIGR01980
879088007868	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
879088007869	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
879088007870	trimerization site [polypeptide binding]; other site
879088007871	active site
879088007872	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
879088007873	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
879088007874	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088007875	catalytic residue [active]
879088007876	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
879088007877	FeS assembly protein SufD; Region: sufD; TIGR01981
879088007878	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
879088007879	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
879088007880	Walker A/P-loop; other site
879088007881	ATP binding site [chemical binding]; other site
879088007882	Q-loop/lid; other site
879088007883	ABC transporter signature motif; other site
879088007884	Walker B; other site
879088007885	D-loop; other site
879088007886	H-loop/switch region; other site
879088007887	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
879088007888	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
879088007889	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088007890	ABC-ATPase subunit interface; other site
879088007891	putative PBP binding loops; other site
879088007892	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
879088007893	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
879088007894	Walker A/P-loop; other site
879088007895	ATP binding site [chemical binding]; other site
879088007896	Q-loop/lid; other site
879088007897	ABC transporter signature motif; other site
879088007898	Walker B; other site
879088007899	D-loop; other site
879088007900	H-loop/switch region; other site
879088007901	NIL domain; Region: NIL; pfam09383
879088007902	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088007903	dimer interface [polypeptide binding]; other site
879088007904	phosphorylation site [posttranslational modification]
879088007905	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088007906	ATP binding site [chemical binding]; other site
879088007907	Mg2+ binding site [ion binding]; other site
879088007908	G-X-G motif; other site
879088007909	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088007910	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088007911	active site
879088007912	phosphorylation site [posttranslational modification]
879088007913	intermolecular recognition site; other site
879088007914	dimerization interface [polypeptide binding]; other site
879088007915	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088007916	DNA binding site [nucleotide binding]
879088007917	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
879088007918	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
879088007919	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088007920	catalytic residues [active]
879088007921	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
879088007922	lipoyl attachment site [posttranslational modification]; other site
879088007923	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
879088007924	ArsC family; Region: ArsC; pfam03960
879088007925	putative ArsC-like catalytic residues; other site
879088007926	putative TRX-like catalytic residues [active]
879088007927	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
879088007928	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
879088007929	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
879088007930	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
879088007931	Walker A/P-loop; other site
879088007932	ATP binding site [chemical binding]; other site
879088007933	Q-loop/lid; other site
879088007934	ABC transporter signature motif; other site
879088007935	Walker B; other site
879088007936	D-loop; other site
879088007937	H-loop/switch region; other site
879088007938	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
879088007939	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
879088007940	ABC-ATPase subunit  interface; other site
879088007941	dimer interface [polypeptide binding]; other site
879088007942	putative PBP binding regions; other site
879088007943	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
879088007944	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
879088007945	intersubunit interface [polypeptide binding]; other site
879088007946	Predicted esterase [General function prediction only]; Region: COG0627
879088007947	S-formylglutathione hydrolase; Region: PLN02442
879088007948	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
879088007949	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088007950	catalytic residue [active]
879088007951	SdpI/YhfL protein family; Region: SdpI; pfam13630
879088007952	CAT RNA binding domain; Region: CAT_RBD; smart01061
879088007953	transcriptional antiterminator BglG; Provisional; Region: PRK09772
879088007954	PRD domain; Region: PRD; pfam00874
879088007955	PRD domain; Region: PRD; pfam00874
879088007956	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
879088007957	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
879088007958	Protein of unknown function (DUF1093); Region: DUF1093; cl02185
879088007959	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
879088007960	Predicted transcriptional regulator [Transcription]; Region: COG2378
879088007961	HTH domain; Region: HTH_11; pfam08279
879088007962	WYL domain; Region: WYL; pfam13280
879088007963	Uncharacterized conserved protein [Function unknown]; Region: COG1434
879088007964	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
879088007965	putative active site [active]
879088007966	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088007967	Leucine rich repeat; Region: LRR_8; pfam13855
879088007968	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
879088007969	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
879088007970	active site
879088007971	catalytic site [active]
879088007972	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
879088007973	putative metal binding site [ion binding]; other site
879088007974	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
879088007975	putative metal binding site [ion binding]; other site
879088007976	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088007977	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
879088007978	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
879088007979	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
879088007980	active site
879088007981	catalytic site [active]
879088007982	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
879088007983	putative metal binding site [ion binding]; other site
879088007984	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088007985	non-specific DNA binding site [nucleotide binding]; other site
879088007986	salt bridge; other site
879088007987	sequence-specific DNA binding site [nucleotide binding]; other site
879088007988	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
879088007989	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
879088007990	SmpB-tmRNA interface; other site
879088007991	ribonuclease R; Region: RNase_R; TIGR02063
879088007992	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
879088007993	RNB domain; Region: RNB; pfam00773
879088007994	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
879088007995	RNA binding site [nucleotide binding]; other site
879088007996	Esterase/lipase [General function prediction only]; Region: COG1647
879088007997	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088007998	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
879088007999	Preprotein translocase SecG subunit; Region: SecG; cl09123
879088008000	Esterase/lipase [General function prediction only]; Region: COG1647
879088008001	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
879088008002	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
879088008003	PGAP1-like protein; Region: PGAP1; pfam07819
879088008004	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
879088008005	enolase; Provisional; Region: eno; PRK00077
879088008006	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
879088008007	dimer interface [polypeptide binding]; other site
879088008008	metal binding site [ion binding]; metal-binding site
879088008009	substrate binding pocket [chemical binding]; other site
879088008010	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
879088008011	phosphoglyceromutase; Provisional; Region: PRK05434
879088008012	triosephosphate isomerase; Provisional; Region: PRK14567
879088008013	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
879088008014	substrate binding site [chemical binding]; other site
879088008015	dimer interface [polypeptide binding]; other site
879088008016	catalytic triad [active]
879088008017	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
879088008018	Phosphoglycerate kinase; Region: PGK; pfam00162
879088008019	substrate binding site [chemical binding]; other site
879088008020	hinge regions; other site
879088008021	ADP binding site [chemical binding]; other site
879088008022	catalytic site [active]
879088008023	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
879088008024	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
879088008025	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
879088008026	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
879088008027	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
879088008028	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
879088008029	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
879088008030	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
879088008031	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088008032	DNA binding site [nucleotide binding]
879088008033	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
879088008034	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
879088008035	active site
879088008036	dimer interface [polypeptide binding]; other site
879088008037	MMPL family; Region: MMPL; pfam03176
879088008038	Sterol-sensing domain of SREBP cleavage-activation; Region: Sterol-sensing; pfam12349
879088008039	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088008040	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088008041	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
879088008042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3397
879088008043	Chitin binding domain; Region: Chitin_bind_3; pfam03067
879088008044	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
879088008045	Interdomain contacts; other site
879088008046	Cytokine receptor motif; other site
879088008047	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
879088008048	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
879088008049	Interdomain contacts; other site
879088008050	Cytokine receptor motif; other site
879088008051	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
879088008052	aromatic chitin/cellulose binding site residues [chemical binding]; other site
879088008053	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
879088008054	aromatic chitin/cellulose binding site residues [chemical binding]; other site
879088008055	Clp protease; Region: CLP_protease; pfam00574
879088008056	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
879088008057	oligomer interface [polypeptide binding]; other site
879088008058	active site residues [active]
879088008059	amino acid transporter; Region: 2A0306; TIGR00909
879088008060	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
879088008061	Bacterial adhesion/invasion protein N terminal; Region: Internalin_N; pfam12354
879088008062	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088008063	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088008064	Substrate binding site [chemical binding]; other site
879088008065	Leucine rich repeat; Region: LRR_8; pfam13855
879088008066	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088008067	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
879088008068	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
879088008069	active site
879088008070	FMN binding site [chemical binding]; other site
879088008071	substrate binding site [chemical binding]; other site
879088008072	homotetramer interface [polypeptide binding]; other site
879088008073	catalytic residue [active]
879088008074	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
879088008075	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
879088008076	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
879088008077	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
879088008078	phosphate binding site [ion binding]; other site
879088008079	putative substrate binding pocket [chemical binding]; other site
879088008080	dimer interface [polypeptide binding]; other site
879088008081	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
879088008082	AAA domain; Region: AAA_18; pfam13238
879088008083	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
879088008084	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
879088008085	active site
879088008086	substrate binding site [chemical binding]; other site
879088008087	metal binding site [ion binding]; metal-binding site
879088008088	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
879088008089	active site
879088008090	catalytic residues [active]
879088008091	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
879088008092	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
879088008093	NAD binding site [chemical binding]; other site
879088008094	homodimer interface [polypeptide binding]; other site
879088008095	active site
879088008096	substrate binding site [chemical binding]; other site
879088008097	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
879088008098	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
879088008099	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088008100	TPR repeat; Region: TPR_11; pfam13414
879088008101	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088008102	binding surface
879088008103	TPR motif; other site
879088008104	Tetratricopeptide repeat; Region: TPR_12; pfam13424
879088008105	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
879088008106	binding surface
879088008107	TPR motif; other site
879088008108	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
879088008109	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
879088008110	putative trimer interface [polypeptide binding]; other site
879088008111	putative CoA binding site [chemical binding]; other site
879088008112	pyrophosphatase PpaX; Provisional; Region: PRK13288
879088008113	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088008114	motif II; other site
879088008115	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
879088008116	HPr kinase/phosphorylase; Provisional; Region: PRK05428
879088008117	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
879088008118	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
879088008119	Hpr binding site; other site
879088008120	active site
879088008121	homohexamer subunit interaction site [polypeptide binding]; other site
879088008122	Predicted membrane protein [Function unknown]; Region: COG1950
879088008123	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
879088008124	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
879088008125	Uncharacterized conserved protein [Function unknown]; Region: COG3595
879088008126	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
879088008127	Uncharacterized conserved protein [Function unknown]; Region: COG3595
879088008128	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
879088008129	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
879088008130	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
879088008131	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
879088008132	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
879088008133	excinuclease ABC subunit B; Provisional; Region: PRK05298
879088008134	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088008135	ATP binding site [chemical binding]; other site
879088008136	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088008137	nucleotide binding region [chemical binding]; other site
879088008138	ATP-binding site [chemical binding]; other site
879088008139	Ultra-violet resistance protein B; Region: UvrB; pfam12344
879088008140	UvrB/uvrC motif; Region: UVR; pfam02151
879088008141	Uncharacterized protein conserved in bacteria [Function unknown]; Region: CsbA; COG4897
879088008142	HD containing hydrolase-like enzyme; Region: HD_2; pfam12917
879088008143	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
879088008144	dimerization interface [polypeptide binding]; other site
879088008145	putative DNA binding site [nucleotide binding]; other site
879088008146	putative Zn2+ binding site [ion binding]; other site
879088008147	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
879088008148	PhoU domain; Region: PhoU; pfam01895
879088008149	PhoU domain; Region: PhoU; pfam01895
879088008150	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
879088008151	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
879088008152	Walker A/P-loop; other site
879088008153	ATP binding site [chemical binding]; other site
879088008154	Q-loop/lid; other site
879088008155	ABC transporter signature motif; other site
879088008156	Walker B; other site
879088008157	D-loop; other site
879088008158	H-loop/switch region; other site
879088008159	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
879088008160	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
879088008161	Walker A/P-loop; other site
879088008162	ATP binding site [chemical binding]; other site
879088008163	Q-loop/lid; other site
879088008164	ABC transporter signature motif; other site
879088008165	Walker B; other site
879088008166	D-loop; other site
879088008167	H-loop/switch region; other site
879088008168	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
879088008169	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088008170	dimer interface [polypeptide binding]; other site
879088008171	conserved gate region; other site
879088008172	putative PBP binding loops; other site
879088008173	ABC-ATPase subunit interface; other site
879088008174	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
879088008175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088008176	dimer interface [polypeptide binding]; other site
879088008177	conserved gate region; other site
879088008178	putative PBP binding loops; other site
879088008179	ABC-ATPase subunit interface; other site
879088008180	PBP superfamily domain; Region: PBP_like_2; cl17296
879088008181	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
879088008182	HAMP domain; Region: HAMP; pfam00672
879088008183	dimerization interface [polypeptide binding]; other site
879088008184	PAS domain; Region: PAS; smart00091
879088008185	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
879088008186	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088008187	dimer interface [polypeptide binding]; other site
879088008188	phosphorylation site [posttranslational modification]
879088008189	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088008190	ATP binding site [chemical binding]; other site
879088008191	Mg2+ binding site [ion binding]; other site
879088008192	G-X-G motif; other site
879088008193	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088008194	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088008195	active site
879088008196	phosphorylation site [posttranslational modification]
879088008197	intermolecular recognition site; other site
879088008198	dimerization interface [polypeptide binding]; other site
879088008199	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088008200	DNA binding site [nucleotide binding]
879088008201	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
879088008202	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
879088008203	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
879088008204	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
879088008205	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
879088008206	putative active site [active]
879088008207	catalytic site [active]
879088008208	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
879088008209	putative active site [active]
879088008210	catalytic site [active]
879088008211	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
879088008212	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
879088008213	Peptidase family M23; Region: Peptidase_M23; pfam01551
879088008214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
879088008215	NlpC/P60 family; Region: NLPC_P60; pfam00877
879088008216	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
879088008217	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
879088008218	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
879088008219	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088008220	Walker A/P-loop; other site
879088008221	ATP binding site [chemical binding]; other site
879088008222	Q-loop/lid; other site
879088008223	ABC transporter signature motif; other site
879088008224	Walker B; other site
879088008225	D-loop; other site
879088008226	H-loop/switch region; other site
879088008227	Uncharacterized conserved protein [Function unknown]; Region: COG1284
879088008228	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088008229	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
879088008230	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
879088008231	peptide chain release factor 2; Validated; Region: prfB; PRK00578
879088008232	This domain is found in peptide chain release factors; Region: PCRF; smart00937
879088008233	RF-1 domain; Region: RF-1; pfam00472
879088008234	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
879088008235	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
879088008236	nucleotide binding region [chemical binding]; other site
879088008237	helicase superfamily c-terminal domain; Region: HELICc; smart00490
879088008238	ATP-binding site [chemical binding]; other site
879088008239	SEC-C motif; Region: SEC-C; pfam02810
879088008240	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
879088008241	30S subunit binding site; other site
879088008242	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
879088008243	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088008244	active site
879088008245	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
879088008246	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088008247	ATP binding site [chemical binding]; other site
879088008248	putative Mg++ binding site [ion binding]; other site
879088008249	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088008250	nucleotide binding region [chemical binding]; other site
879088008251	ATP-binding site [chemical binding]; other site
879088008252	EDD domain protein, DegV family; Region: DegV; TIGR00762
879088008253	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
879088008254	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
879088008255	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088008256	active site
879088008257	phosphorylation site [posttranslational modification]
879088008258	intermolecular recognition site; other site
879088008259	dimerization interface [polypeptide binding]; other site
879088008260	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
879088008261	DNA binding residues [nucleotide binding]
879088008262	dimerization interface [polypeptide binding]; other site
879088008263	Uncharacterized conserved protein [Function unknown]; Region: COG1739
879088008264	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
879088008265	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
879088008266	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
879088008267	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
879088008268	Transcriptional regulator [Transcription]; Region: LytR; COG1316
879088008269	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
879088008270	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
879088008271	Mg++ binding site [ion binding]; other site
879088008272	putative catalytic motif [active]
879088008273	substrate binding site [chemical binding]; other site
879088008274	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
879088008275	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
879088008276	active site
879088008277	octamer interface [polypeptide binding]; other site
879088008278	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
879088008279	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
879088008280	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008281	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008282	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
879088008283	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
879088008284	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
879088008285	dimer interface [polypeptide binding]; other site
879088008286	ssDNA binding site [nucleotide binding]; other site
879088008287	tetramer (dimer of dimers) interface [polypeptide binding]; other site
879088008288	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
879088008289	rod shape-determining protein Mbl; Provisional; Region: PRK13928
879088008290	MreB and similar proteins; Region: MreB_like; cd10225
879088008291	nucleotide binding site [chemical binding]; other site
879088008292	Mg binding site [ion binding]; other site
879088008293	putative protofilament interaction site [polypeptide binding]; other site
879088008294	RodZ interaction site [polypeptide binding]; other site
879088008295	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
879088008296	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
879088008297	hinge; other site
879088008298	active site
879088008299	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
879088008300	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
879088008301	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
879088008302	gamma subunit interface [polypeptide binding]; other site
879088008303	epsilon subunit interface [polypeptide binding]; other site
879088008304	LBP interface [polypeptide binding]; other site
879088008305	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
879088008306	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
879088008307	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
879088008308	alpha subunit interaction interface [polypeptide binding]; other site
879088008309	Walker A motif; other site
879088008310	ATP binding site [chemical binding]; other site
879088008311	Walker B motif; other site
879088008312	inhibitor binding site; inhibition site
879088008313	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
879088008314	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
879088008315	core domain interface [polypeptide binding]; other site
879088008316	delta subunit interface [polypeptide binding]; other site
879088008317	epsilon subunit interface [polypeptide binding]; other site
879088008318	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
879088008319	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
879088008320	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
879088008321	beta subunit interaction interface [polypeptide binding]; other site
879088008322	Walker A motif; other site
879088008323	ATP binding site [chemical binding]; other site
879088008324	Walker B motif; other site
879088008325	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
879088008326	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
879088008327	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
879088008328	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
879088008329	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
879088008330	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
879088008331	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
879088008332	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
879088008333	ATP synthase I chain; Region: ATP_synt_I; pfam03899
879088008334	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
879088008335	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
879088008336	active site
879088008337	homodimer interface [polypeptide binding]; other site
879088008338	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
879088008339	active site
879088008340	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
879088008341	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
879088008342	dimer interface [polypeptide binding]; other site
879088008343	active site
879088008344	glycine-pyridoxal phosphate binding site [chemical binding]; other site
879088008345	folate binding site [chemical binding]; other site
879088008346	Low molecular weight phosphatase family; Region: LMWPc; cd00115
879088008347	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
879088008348	active site
879088008349	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
879088008350	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
879088008351	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
879088008352	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088008353	S-adenosylmethionine binding site [chemical binding]; other site
879088008354	peptide chain release factor 1; Validated; Region: prfA; PRK00591
879088008355	This domain is found in peptide chain release factors; Region: PCRF; smart00937
879088008356	RF-1 domain; Region: RF-1; pfam00472
879088008357	thymidine kinase; Provisional; Region: PRK04296
879088008358	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
879088008359	ATP binding site [chemical binding]; other site
879088008360	Walker A motif; other site
879088008361	Walker B motif; other site
879088008362	homoserine kinase; Provisional; Region: PRK01212
879088008363	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
879088008364	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
879088008365	threonine synthase; Reviewed; Region: PRK06721
879088008366	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
879088008367	homodimer interface [polypeptide binding]; other site
879088008368	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088008369	catalytic residue [active]
879088008370	homoserine dehydrogenase; Provisional; Region: PRK06349
879088008371	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
879088008372	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
879088008373	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
879088008374	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
879088008375	Predicted membrane protein [Function unknown]; Region: COG2246
879088008376	GtrA-like protein; Region: GtrA; pfam04138
879088008377	transcription termination factor Rho; Provisional; Region: rho; PRK09376
879088008378	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
879088008379	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
879088008380	RNA binding site [nucleotide binding]; other site
879088008381	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
879088008382	multimer interface [polypeptide binding]; other site
879088008383	Walker A motif; other site
879088008384	ATP binding site [chemical binding]; other site
879088008385	Walker B motif; other site
879088008386	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
879088008387	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
879088008388	hinge; other site
879088008389	active site
879088008390	Predicted integral membrane protein [Function unknown]; Region: COG0392
879088008391	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
879088008392	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
879088008393	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
879088008394	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
879088008395	putative ADP-binding pocket [chemical binding]; other site
879088008396	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
879088008397	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
879088008398	intersubunit interface [polypeptide binding]; other site
879088008399	active site
879088008400	zinc binding site [ion binding]; other site
879088008401	Na+ binding site [ion binding]; other site
879088008402	putative lipid kinase; Reviewed; Region: PRK13055
879088008403	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
879088008404	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: COG5632
879088008405	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
879088008406	substrate binding site [chemical binding]; other site
879088008407	SH3-like domain; Region: SH3_8; pfam13457
879088008408	SH3-like domain; Region: SH3_8; pfam13457
879088008409	CTP synthetase; Validated; Region: pyrG; PRK05380
879088008410	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
879088008411	Catalytic site [active]
879088008412	active site
879088008413	UTP binding site [chemical binding]; other site
879088008414	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
879088008415	active site
879088008416	putative oxyanion hole; other site
879088008417	catalytic triad [active]
879088008418	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
879088008419	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
879088008420	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
879088008421	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
879088008422	active site
879088008423	HIGH motif; other site
879088008424	KMSK motif region; other site
879088008425	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
879088008426	tRNA binding surface [nucleotide binding]; other site
879088008427	anticodon binding site; other site
879088008428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4506
879088008429	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
879088008430	Peptidase family M50; Region: Peptidase_M50; pfam02163
879088008431	active site
879088008432	putative substrate binding region [chemical binding]; other site
879088008433	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
879088008434	active site 1 [active]
879088008435	dimer interface [polypeptide binding]; other site
879088008436	hexamer interface [polypeptide binding]; other site
879088008437	active site 2 [active]
879088008438	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
879088008439	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088008440	Zn2+ binding site [ion binding]; other site
879088008441	Mg2+ binding site [ion binding]; other site
879088008442	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
879088008443	conserved hypothetical protein TIGR01655; Region: yxeA_fam
879088008444	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
879088008445	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
879088008446	peptide binding site [polypeptide binding]; other site
879088008447	Predicted integral membrane protein [Function unknown]; Region: COG5658
879088008448	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
879088008449	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
879088008450	catalytic triad [active]
879088008451	metal binding site [ion binding]; metal-binding site
879088008452	conserved cis-peptide bond; other site
879088008453	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
879088008454	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
879088008455	folate binding site [chemical binding]; other site
879088008456	NADP+ binding site [chemical binding]; other site
879088008457	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
879088008458	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
879088008459	putative NAD(P) binding site [chemical binding]; other site
879088008460	dimer interface [polypeptide binding]; other site
879088008461	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
879088008462	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
879088008463	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088008464	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088008465	active site
879088008466	motif I; other site
879088008467	motif II; other site
879088008468	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
879088008469	Uncharacterized conserved protein [Function unknown]; Region: COG1359
879088008470	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
879088008471	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088008472	Walker A/P-loop; other site
879088008473	ATP binding site [chemical binding]; other site
879088008474	Q-loop/lid; other site
879088008475	ABC transporter signature motif; other site
879088008476	Walker B; other site
879088008477	D-loop; other site
879088008478	H-loop/switch region; other site
879088008479	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
879088008480	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
879088008481	FtsX-like permease family; Region: FtsX; pfam02687
879088008482	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
879088008483	dimerization interface [polypeptide binding]; other site
879088008484	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088008485	dimer interface [polypeptide binding]; other site
879088008486	phosphorylation site [posttranslational modification]
879088008487	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088008488	ATP binding site [chemical binding]; other site
879088008489	Mg2+ binding site [ion binding]; other site
879088008490	G-X-G motif; other site
879088008491	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088008492	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088008493	active site
879088008494	phosphorylation site [posttranslational modification]
879088008495	intermolecular recognition site; other site
879088008496	dimerization interface [polypeptide binding]; other site
879088008497	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088008498	DNA binding site [nucleotide binding]
879088008499	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
879088008500	Uncharacterized conserved protein [Function unknown]; Region: COG2427
879088008501	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
879088008502	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
879088008503	catalytic loop [active]
879088008504	iron binding site [ion binding]; other site
879088008505	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
879088008506	4Fe-4S binding domain; Region: Fer4; pfam00037
879088008507	4Fe-4S binding domain; Region: Fer4; pfam00037
879088008508	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
879088008509	[4Fe-4S] binding site [ion binding]; other site
879088008510	molybdopterin cofactor binding site; other site
879088008511	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
879088008512	molybdopterin cofactor binding site; other site
879088008513	Uncharacterized conserved protein [Function unknown]; Region: COG1912
879088008514	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088008515	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088008516	putative substrate translocation pore; other site
879088008517	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088008518	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088008519	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
879088008520	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
879088008521	Walker A motif; other site
879088008522	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088008523	SH3-like domain; Region: SH3_8; pfam13457
879088008524	SH3-like domain; Region: SH3_8; pfam13457
879088008525	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088008526	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088008527	active site
879088008528	catalytic tetrad [active]
879088008529	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088008530	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088008531	DNA binding residues [nucleotide binding]
879088008532	putative dimer interface [polypeptide binding]; other site
879088008533	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
879088008534	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
879088008535	23S rRNA interface [nucleotide binding]; other site
879088008536	L3 interface [polypeptide binding]; other site
879088008537	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
879088008538	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
879088008539	dimerization interface 3.5A [polypeptide binding]; other site
879088008540	active site
879088008541	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
879088008542	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
879088008543	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
879088008544	Walker A/P-loop; other site
879088008545	ATP binding site [chemical binding]; other site
879088008546	Q-loop/lid; other site
879088008547	ABC transporter signature motif; other site
879088008548	Walker B; other site
879088008549	D-loop; other site
879088008550	H-loop/switch region; other site
879088008551	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
879088008552	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
879088008553	Walker A/P-loop; other site
879088008554	ATP binding site [chemical binding]; other site
879088008555	Q-loop/lid; other site
879088008556	ABC transporter signature motif; other site
879088008557	Walker B; other site
879088008558	D-loop; other site
879088008559	H-loop/switch region; other site
879088008560	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
879088008561	MgtC family; Region: MgtC; pfam02308
879088008562	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
879088008563	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
879088008564	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
879088008565	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
879088008566	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
879088008567	alphaNTD - beta interaction site [polypeptide binding]; other site
879088008568	alphaNTD homodimer interface [polypeptide binding]; other site
879088008569	alphaNTD - beta' interaction site [polypeptide binding]; other site
879088008570	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
879088008571	30S ribosomal protein S11; Validated; Region: PRK05309
879088008572	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
879088008573	30S ribosomal protein S13; Region: bact_S13; TIGR03631
879088008574	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
879088008575	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
879088008576	rRNA binding site [nucleotide binding]; other site
879088008577	predicted 30S ribosome binding site; other site
879088008578	adenylate kinase; Reviewed; Region: adk; PRK00279
879088008579	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
879088008580	AMP-binding site [chemical binding]; other site
879088008581	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
879088008582	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
879088008583	SecY translocase; Region: SecY; pfam00344
879088008584	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
879088008585	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
879088008586	23S rRNA binding site [nucleotide binding]; other site
879088008587	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
879088008588	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
879088008589	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
879088008590	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
879088008591	5S rRNA interface [nucleotide binding]; other site
879088008592	L27 interface [polypeptide binding]; other site
879088008593	23S rRNA interface [nucleotide binding]; other site
879088008594	L5 interface [polypeptide binding]; other site
879088008595	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
879088008596	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
879088008597	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
879088008598	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
879088008599	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
879088008600	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
879088008601	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
879088008602	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
879088008603	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
879088008604	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
879088008605	RNA binding site [nucleotide binding]; other site
879088008606	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
879088008607	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
879088008608	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
879088008609	23S rRNA interface [nucleotide binding]; other site
879088008610	putative translocon interaction site; other site
879088008611	signal recognition particle (SRP54) interaction site; other site
879088008612	L23 interface [polypeptide binding]; other site
879088008613	trigger factor interaction site; other site
879088008614	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
879088008615	23S rRNA interface [nucleotide binding]; other site
879088008616	5S rRNA interface [nucleotide binding]; other site
879088008617	putative antibiotic binding site [chemical binding]; other site
879088008618	L25 interface [polypeptide binding]; other site
879088008619	L27 interface [polypeptide binding]; other site
879088008620	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
879088008621	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
879088008622	G-X-X-G motif; other site
879088008623	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
879088008624	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
879088008625	putative translocon binding site; other site
879088008626	protein-rRNA interface [nucleotide binding]; other site
879088008627	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
879088008628	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
879088008629	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
879088008630	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
879088008631	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
879088008632	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
879088008633	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
879088008634	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
879088008635	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
879088008636	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional; Region: PRK13387
879088008637	UbiA prenyltransferase family; Region: UbiA; pfam01040
879088008638	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
879088008639	ApbE family; Region: ApbE; pfam02424
879088008640	Major membrane immunogen, membrane-anchored lipoprotein [Function unknown]; Region: COG4939
879088008641	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
879088008642	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
879088008643	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
879088008644	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
879088008645	Predicted membrane protein [Function unknown]; Region: COG2259
879088008646	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
879088008647	trimer interface [polypeptide binding]; other site
879088008648	Predicted membrane protein [Function unknown]; Region: COG4769
879088008649	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
879088008650	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
879088008651	substrate binding pocket [chemical binding]; other site
879088008652	chain length determination region; other site
879088008653	substrate-Mg2+ binding site; other site
879088008654	catalytic residues [active]
879088008655	aspartate-rich region 1; other site
879088008656	active site lid residues [active]
879088008657	aspartate-rich region 2; other site
879088008658	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
879088008659	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
879088008660	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
879088008661	active site
879088008662	metal binding site [ion binding]; metal-binding site
879088008663	Protein of unknown function (DUF4003); Region: DUF4003; pfam13170
879088008664	hypothetical protein; Provisional; Region: PRK02947
879088008665	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088008666	putative active site [active]
879088008667	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
879088008668	Uncharacterized protein, putative amidase [General function prediction only]; Region: COG1402
879088008669	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
879088008670	active site
879088008671	substrate binding pocket [chemical binding]; other site
879088008672	homodimer interaction site [polypeptide binding]; other site
879088008673	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
879088008674	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
879088008675	active site
879088008676	P-loop; other site
879088008677	phosphorylation site [posttranslational modification]
879088008678	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088008679	active site
879088008680	phosphorylation site [posttranslational modification]
879088008681	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088008682	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088008683	PRD domain; Region: PRD; pfam00874
879088008684	PRD domain; Region: PRD; pfam00874
879088008685	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088008686	active site
879088008687	P-loop; other site
879088008688	phosphorylation site [posttranslational modification]
879088008689	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088008690	active site
879088008691	phosphorylation site [posttranslational modification]
879088008692	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
879088008693	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088008694	Walker A/P-loop; other site
879088008695	ATP binding site [chemical binding]; other site
879088008696	Q-loop/lid; other site
879088008697	ABC transporter signature motif; other site
879088008698	Walker B; other site
879088008699	D-loop; other site
879088008700	H-loop/switch region; other site
879088008701	elongation factor Tu; Reviewed; Region: PRK00049
879088008702	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
879088008703	G1 box; other site
879088008704	GEF interaction site [polypeptide binding]; other site
879088008705	GTP/Mg2+ binding site [chemical binding]; other site
879088008706	Switch I region; other site
879088008707	G2 box; other site
879088008708	G3 box; other site
879088008709	Switch II region; other site
879088008710	G4 box; other site
879088008711	G5 box; other site
879088008712	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
879088008713	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
879088008714	Antibiotic Binding Site [chemical binding]; other site
879088008715	elongation factor G; Reviewed; Region: PRK00007
879088008716	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
879088008717	G1 box; other site
879088008718	putative GEF interaction site [polypeptide binding]; other site
879088008719	GTP/Mg2+ binding site [chemical binding]; other site
879088008720	Switch I region; other site
879088008721	G2 box; other site
879088008722	G3 box; other site
879088008723	Switch II region; other site
879088008724	G4 box; other site
879088008725	G5 box; other site
879088008726	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
879088008727	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
879088008728	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
879088008729	30S ribosomal protein S7; Validated; Region: PRK05302
879088008730	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
879088008731	S17 interaction site [polypeptide binding]; other site
879088008732	S8 interaction site; other site
879088008733	16S rRNA interaction site [nucleotide binding]; other site
879088008734	streptomycin interaction site [chemical binding]; other site
879088008735	23S rRNA interaction site [nucleotide binding]; other site
879088008736	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
879088008737	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
879088008738	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
879088008739	Zn2+ binding site [ion binding]; other site
879088008740	Mg2+ binding site [ion binding]; other site
879088008741	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
879088008742	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088008743	Coenzyme A binding pocket [chemical binding]; other site
879088008744	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
879088008745	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088008746	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088008747	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
879088008748	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
879088008749	substrate binding site [chemical binding]; other site
879088008750	hexamer interface [polypeptide binding]; other site
879088008751	metal binding site [ion binding]; metal-binding site
879088008752	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
879088008753	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
879088008754	TPP-binding site [chemical binding]; other site
879088008755	dimer interface [polypeptide binding]; other site
879088008756	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
879088008757	PYR/PP interface [polypeptide binding]; other site
879088008758	dimer interface [polypeptide binding]; other site
879088008759	TPP binding site [chemical binding]; other site
879088008760	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
879088008761	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
879088008762	substrate binding site [chemical binding]; other site
879088008763	hexamer interface [polypeptide binding]; other site
879088008764	metal binding site [ion binding]; metal-binding site
879088008765	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
879088008766	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
879088008767	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
879088008768	putative NAD(P) binding site [chemical binding]; other site
879088008769	catalytic Zn binding site [ion binding]; other site
879088008770	structural Zn binding site [ion binding]; other site
879088008771	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
879088008772	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
879088008773	putative NAD(P) binding site [chemical binding]; other site
879088008774	catalytic Zn binding site [ion binding]; other site
879088008775	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
879088008776	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
879088008777	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
879088008778	active site
879088008779	P-loop; other site
879088008780	phosphorylation site [posttranslational modification]
879088008781	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088008782	active site
879088008783	phosphorylation site [posttranslational modification]
879088008784	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088008785	PRD domain; Region: PRD; pfam00874
879088008786	PRD domain; Region: PRD; pfam00874
879088008787	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088008788	active site
879088008789	P-loop; other site
879088008790	phosphorylation site [posttranslational modification]
879088008791	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: PtsN; COG1762
879088008792	active site
879088008793	phosphorylation site [posttranslational modification]
879088008794	Predicted membrane protein [Function unknown]; Region: COG4905
879088008795	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
879088008796	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
879088008797	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
879088008798	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
879088008799	active site
879088008800	Helix-turn-helix domain; Region: HTH_18; pfam12833
879088008801	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
879088008802	Ligand Binding Site [chemical binding]; other site
879088008803	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
879088008804	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
879088008805	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
879088008806	active site
879088008807	DNA binding site [nucleotide binding]
879088008808	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
879088008809	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
879088008810	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
879088008811	active site
879088008812	phosphorylation site [posttranslational modification]
879088008813	intermolecular recognition site; other site
879088008814	dimerization interface [polypeptide binding]; other site
879088008815	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
879088008816	DNA binding site [nucleotide binding]
879088008817	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
879088008818	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
879088008819	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
879088008820	Ligand Binding Site [chemical binding]; other site
879088008821	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
879088008822	GAF domain; Region: GAF_3; pfam13492
879088008823	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
879088008824	dimer interface [polypeptide binding]; other site
879088008825	phosphorylation site [posttranslational modification]
879088008826	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
879088008827	ATP binding site [chemical binding]; other site
879088008828	Mg2+ binding site [ion binding]; other site
879088008829	G-X-G motif; other site
879088008830	K+-transporting ATPase, c chain [Inorganic ion transport and metabolism]; Region: KdpC; COG2156
879088008831	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
879088008832	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088008833	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
879088008834	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088008835	active site
879088008836	P-loop; other site
879088008837	phosphorylation site [posttranslational modification]
879088008838	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088008839	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088008840	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088008841	methionine cluster; other site
879088008842	active site
879088008843	phosphorylation site [posttranslational modification]
879088008844	metal binding site [ion binding]; metal-binding site
879088008845	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
879088008846	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
879088008847	magnesium-translocating P-type ATPase; Region: ATPase-IIIB_Mg; TIGR01524
879088008848	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
879088008849	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
879088008850	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
879088008851	Soluble P-type ATPase [General function prediction only]; Region: COG4087
879088008852	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
879088008853	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088008854	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088008855	autolysin; Reviewed; Region: PRK06347
879088008856	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
879088008857	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008858	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008859	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008860	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
879088008861	Protein of unknown function (DUF970); Region: DUF970; pfam06153
879088008862	thymidylate kinase; Validated; Region: tmk; PRK00698
879088008863	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
879088008864	TMP-binding site; other site
879088008865	ATP-binding site [chemical binding]; other site
879088008866	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
879088008867	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
879088008868	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088008869	catalytic residue [active]
879088008870	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
879088008871	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
879088008872	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
879088008873	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
879088008874	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
879088008875	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
879088008876	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088008877	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088008878	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088008879	putative active site [active]
879088008880	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
879088008881	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088008882	active site
879088008883	motif I; other site
879088008884	motif II; other site
879088008885	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
879088008886	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
879088008887	nudix motif; other site
879088008888	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
879088008889	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
879088008890	active site
879088008891	catalytic tetrad [active]
879088008892	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
879088008893	recombination protein RecR; Reviewed; Region: recR; PRK00076
879088008894	RecR protein; Region: RecR; pfam02132
879088008895	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
879088008896	putative active site [active]
879088008897	putative metal-binding site [ion binding]; other site
879088008898	tetramer interface [polypeptide binding]; other site
879088008899	hypothetical protein; Validated; Region: PRK00153
879088008900	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
879088008901	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
879088008902	Walker A motif; other site
879088008903	ATP binding site [chemical binding]; other site
879088008904	Walker B motif; other site
879088008905	arginine finger; other site
879088008906	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
879088008907	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
879088008908	Protein of unknown function (DUF3188); Region: DUF3188; pfam11384
879088008909	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088008910	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088008911	Domain of unknown function (DUF4307); Region: DUF4307; pfam14155
879088008912	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
879088008913	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
879088008914	N- and C-terminal domain interface [polypeptide binding]; other site
879088008915	active site
879088008916	catalytic site [active]
879088008917	metal binding site [ion binding]; metal-binding site
879088008918	carbohydrate binding site [chemical binding]; other site
879088008919	ATP binding site [chemical binding]; other site
879088008920	SH3-like domain; Region: SH3_8; pfam13457
879088008921	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
879088008922	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
879088008923	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088008924	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
879088008925	Walker A/P-loop; other site
879088008926	ATP binding site [chemical binding]; other site
879088008927	Q-loop/lid; other site
879088008928	ABC transporter signature motif; other site
879088008929	Walker B; other site
879088008930	D-loop; other site
879088008931	H-loop/switch region; other site
879088008932	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
879088008933	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088008934	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088008935	Walker A/P-loop; other site
879088008936	ATP binding site [chemical binding]; other site
879088008937	Q-loop/lid; other site
879088008938	ABC transporter signature motif; other site
879088008939	Walker B; other site
879088008940	D-loop; other site
879088008941	H-loop/switch region; other site
879088008942	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
879088008943	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
879088008944	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
879088008945	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
879088008946	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
879088008947	nucleoside/Zn binding site; other site
879088008948	dimer interface [polypeptide binding]; other site
879088008949	catalytic motif [active]
879088008950	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
879088008951	Medium-chain acyl-CoA synthetase (MACS or ACSM); Region: MACS_like; cd05972
879088008952	active site
879088008953	acyl-activating enzyme (AAE) consensus motif; other site
879088008954	putative CoA binding site [chemical binding]; other site
879088008955	AMP binding site [chemical binding]; other site
879088008956	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
879088008957	substrate binding site [chemical binding]; other site
879088008958	activation loop (A-loop); other site
879088008959	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
879088008960	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
879088008961	active site
879088008962	trimer interface [polypeptide binding]; other site
879088008963	allosteric site; other site
879088008964	active site lid [active]
879088008965	hexamer (dimer of trimers) interface [polypeptide binding]; other site
879088008966	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
879088008967	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
879088008968	DNA binding residues [nucleotide binding]
879088008969	drug binding residues [chemical binding]; other site
879088008970	dimer interface [polypeptide binding]; other site
879088008971	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
879088008972	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
879088008973	Coenzyme A binding pocket [chemical binding]; other site
879088008974	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
879088008975	dimer interface [polypeptide binding]; other site
879088008976	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
879088008977	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
879088008978	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
879088008979	MarR family; Region: MarR; pfam01047
879088008980	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
879088008981	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
879088008982	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
879088008983	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
879088008984	DNA binding residues [nucleotide binding]
879088008985	putative dimer interface [polypeptide binding]; other site
879088008986	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
879088008987	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
879088008988	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088008989	active site
879088008990	motif I; other site
879088008991	motif II; other site
879088008992	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088008993	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088008994	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088008995	putative active site [active]
879088008996	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
879088008997	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088008998	active site
879088008999	phosphorylation site [posttranslational modification]
879088009000	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
879088009001	active site
879088009002	P-loop; other site
879088009003	phosphorylation site [posttranslational modification]
879088009004	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
879088009005	alpha-mannosidase; Provisional; Region: PRK09819
879088009006	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
879088009007	active site
879088009008	metal binding site [ion binding]; metal-binding site
879088009009	catalytic site [active]
879088009010	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
879088009011	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
879088009012	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
879088009013	active site
879088009014	homodimer interface [polypeptide binding]; other site
879088009015	catalytic site [active]
879088009016	glycerate kinase; Region: TIGR00045
879088009017	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088009018	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088009019	DNA binding site [nucleotide binding]
879088009020	domain linker motif; other site
879088009021	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
879088009022	putative dimerization interface [polypeptide binding]; other site
879088009023	putative ligand binding site [chemical binding]; other site
879088009024	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
879088009025	Domain of unknown function DUF21; Region: DUF21; pfam01595
879088009026	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
879088009027	Transporter associated domain; Region: CorC_HlyC; pfam03471
879088009028	NAD-dependent deacetylase; Provisional; Region: PRK00481
879088009029	SIR2H: Uncharacterized prokaryotic Sir2 homologs from several gram positive bacterial species and Fusobacteria; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone...; Region: SIR2H; cd01411
879088009030	NAD+ binding site [chemical binding]; other site
879088009031	substrate binding site [chemical binding]; other site
879088009032	putative Zn binding site [ion binding]; other site
879088009033	Pathogenicity locus; Region: Cdd1; pfam11731
879088009034	drug efflux system protein MdtG; Provisional; Region: PRK09874
879088009035	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009036	putative substrate translocation pore; other site
879088009037	Src Homology 3 domain superfamily; Region: SH3; cl17036
879088009038	Variant SH3 domain; Region: SH3_2; pfam07653
879088009039	peptide ligand binding site [polypeptide binding]; other site
879088009040	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
879088009041	active site
879088009042	intersubunit interactions; other site
879088009043	catalytic residue [active]
879088009044	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
879088009045	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
879088009046	ligand binding site [chemical binding]; other site
879088009047	flexible hinge region; other site
879088009048	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
879088009049	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088009050	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088009051	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088009052	Walker A/P-loop; other site
879088009053	ATP binding site [chemical binding]; other site
879088009054	Q-loop/lid; other site
879088009055	ABC transporter signature motif; other site
879088009056	Walker B; other site
879088009057	D-loop; other site
879088009058	H-loop/switch region; other site
879088009059	TfoX C-terminal domain; Region: TfoX_C; pfam04994
879088009060	seryl-tRNA synthetase; Provisional; Region: PRK05431
879088009061	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
879088009062	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
879088009063	dimer interface [polypeptide binding]; other site
879088009064	active site
879088009065	motif 1; other site
879088009066	motif 2; other site
879088009067	motif 3; other site
879088009068	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
879088009069	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
879088009070	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
879088009071	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
879088009072	glutamine binding [chemical binding]; other site
879088009073	catalytic triad [active]
879088009074	aminodeoxychorismate synthase; Provisional; Region: PRK07508
879088009075	chorismate binding enzyme; Region: Chorismate_bind; cl10555
879088009076	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
879088009077	substrate-cofactor binding pocket; other site
879088009078	homodimer interface [polypeptide binding]; other site
879088009079	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
879088009080	pyridoxal 5'-phosphate binding site [chemical binding]; other site
879088009081	catalytic residue [active]
879088009082	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088009083	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088009084	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088009085	Walker A/P-loop; other site
879088009086	ATP binding site [chemical binding]; other site
879088009087	Q-loop/lid; other site
879088009088	ABC transporter signature motif; other site
879088009089	Walker B; other site
879088009090	D-loop; other site
879088009091	H-loop/switch region; other site
879088009092	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
879088009093	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
879088009094	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
879088009095	Walker A/P-loop; other site
879088009096	ATP binding site [chemical binding]; other site
879088009097	Q-loop/lid; other site
879088009098	ABC transporter signature motif; other site
879088009099	Walker B; other site
879088009100	D-loop; other site
879088009101	H-loop/switch region; other site
879088009102	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
879088009103	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
879088009104	Ligand binding site; other site
879088009105	Putative Catalytic site; other site
879088009106	DXD motif; other site
879088009107	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
879088009108	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
879088009109	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
879088009110	Predicted acyl esterases [General function prediction only]; Region: COG2936
879088009111	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
879088009112	DNA topoisomerase III; Provisional; Region: PRK07726
879088009113	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
879088009114	active site
879088009115	putative interdomain interaction site [polypeptide binding]; other site
879088009116	putative metal-binding site [ion binding]; other site
879088009117	putative nucleotide binding site [chemical binding]; other site
879088009118	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
879088009119	domain I; other site
879088009120	DNA binding groove [nucleotide binding]
879088009121	phosphate binding site [ion binding]; other site
879088009122	domain II; other site
879088009123	domain III; other site
879088009124	nucleotide binding site [chemical binding]; other site
879088009125	catalytic site [active]
879088009126	domain IV; other site
879088009127	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
879088009128	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
879088009129	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
879088009130	ATP binding site [chemical binding]; other site
879088009131	putative Mg++ binding site [ion binding]; other site
879088009132	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
879088009133	nucleotide binding region [chemical binding]; other site
879088009134	ATP-binding site [chemical binding]; other site
879088009135	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
879088009136	HRDC domain; Region: HRDC; pfam00570
879088009137	IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]; Region: GuaB; COG0516
879088009138	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
879088009139	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
879088009140	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
879088009141	active site
879088009142	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
879088009143	putative ADP-ribose binding site [chemical binding]; other site
879088009144	putative active site [active]
879088009145	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
879088009146	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088009147	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088009148	ABC transporter; Region: ABC_tran_2; pfam12848
879088009149	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
879088009150	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
879088009151	beta-galactosidase; Region: BGL; TIGR03356
879088009152	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088009153	active site
879088009154	P-loop; other site
879088009155	phosphorylation site [posttranslational modification]
879088009156	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
879088009157	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088009158	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088009159	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088009160	nucleotide binding site [chemical binding]; other site
879088009161	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088009162	methionine cluster; other site
879088009163	active site
879088009164	phosphorylation site [posttranslational modification]
879088009165	metal binding site [ion binding]; metal-binding site
879088009166	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088009167	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088009168	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088009169	putative active site [active]
879088009170	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
879088009171	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
879088009172	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
879088009173	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
879088009174	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
879088009175	Walker A/P-loop; other site
879088009176	ATP binding site [chemical binding]; other site
879088009177	Q-loop/lid; other site
879088009178	ABC transporter signature motif; other site
879088009179	Walker B; other site
879088009180	D-loop; other site
879088009181	H-loop/switch region; other site
879088009182	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
879088009183	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
879088009184	ATP-grasp domain; Region: ATP-grasp_4; cl17255
879088009185	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
879088009186	beta-galactosidase; Region: BGL; TIGR03356
879088009187	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
879088009188	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
879088009189	active site turn [active]
879088009190	phosphorylation site [posttranslational modification]
879088009191	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
879088009192	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
879088009193	HPr interaction site; other site
879088009194	glycerol kinase (GK) interaction site [polypeptide binding]; other site
879088009195	active site
879088009196	phosphorylation site [posttranslational modification]
879088009197	transcriptional antiterminator BglG; Provisional; Region: PRK09772
879088009198	CAT RNA binding domain; Region: CAT_RBD; smart01061
879088009199	PRD domain; Region: PRD; pfam00874
879088009200	PRD domain; Region: PRD; pfam00874
879088009201	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
879088009202	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
879088009203	Walker A/P-loop; other site
879088009204	ATP binding site [chemical binding]; other site
879088009205	Q-loop/lid; other site
879088009206	ABC transporter signature motif; other site
879088009207	Walker B; other site
879088009208	D-loop; other site
879088009209	H-loop/switch region; other site
879088009210	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
879088009211	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
879088009212	bacteriocin, lactococcin 972 family; Region: lactococcin_972; TIGR01653
879088009213	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
879088009214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009215	putative substrate translocation pore; other site
879088009216	GTP-binding protein YchF; Reviewed; Region: PRK09601
879088009217	YchF GTPase; Region: YchF; cd01900
879088009218	G1 box; other site
879088009219	GTP/Mg2+ binding site [chemical binding]; other site
879088009220	Switch I region; other site
879088009221	G2 box; other site
879088009222	Switch II region; other site
879088009223	G3 box; other site
879088009224	G4 box; other site
879088009225	G5 box; other site
879088009226	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
879088009227	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
879088009228	methionine cluster; other site
879088009229	active site
879088009230	phosphorylation site [posttranslational modification]
879088009231	metal binding site [ion binding]; metal-binding site
879088009232	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
879088009233	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
879088009234	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
879088009235	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
879088009236	active site
879088009237	P-loop; other site
879088009238	phosphorylation site [posttranslational modification]
879088009239	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
879088009240	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
879088009241	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
879088009242	HTH domain; Region: HTH_11; pfam08279
879088009243	Mga helix-turn-helix domain; Region: Mga; pfam05043
879088009244	PRD domain; Region: PRD; pfam00874
879088009245	PRD domain; Region: PRD; pfam00874
879088009246	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
879088009247	active site
879088009248	P-loop; other site
879088009249	phosphorylation site [posttranslational modification]
879088009250	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088009251	active site
879088009252	phosphorylation site [posttranslational modification]
879088009253	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
879088009254	Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154
879088009255	tetramer interface [polypeptide binding]; other site
879088009256	heme binding pocket [chemical binding]; other site
879088009257	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4481
879088009258	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
879088009259	ParB-like nuclease domain; Region: ParB; smart00470
879088009260	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
879088009261	salt bridge; other site
879088009262	non-specific DNA binding site [nucleotide binding]; other site
879088009263	sequence-specific DNA binding site [nucleotide binding]; other site
879088009264	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
879088009265	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
879088009266	P-loop; other site
879088009267	Magnesium ion binding site [ion binding]; other site
879088009268	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
879088009269	Magnesium ion binding site [ion binding]; other site
879088009270	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
879088009271	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088009272	non-specific DNA binding site [nucleotide binding]; other site
879088009273	salt bridge; other site
879088009274	sequence-specific DNA binding site [nucleotide binding]; other site
879088009275	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
879088009276	ParB-like nuclease domain; Region: ParBc; pfam02195
879088009277	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
879088009278	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
879088009279	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
879088009280	putative active site [active]
879088009281	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
879088009282	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
879088009283	nucleotide binding site [chemical binding]; other site
879088009284	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
879088009285	active site
879088009286	phosphorylation site [posttranslational modification]
879088009287	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
879088009288	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088009289	motif II; other site
879088009290	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
879088009291	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
879088009292	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
879088009293	active site
879088009294	P-loop; other site
879088009295	phosphorylation site [posttranslational modification]
879088009296	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088009297	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088009298	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
879088009299	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
879088009300	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
879088009301	putative active site cavity [active]
879088009302	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
879088009303	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
879088009304	S-adenosylmethionine binding site [chemical binding]; other site
879088009305	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
879088009306	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
879088009307	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
879088009308	Abi-like protein; Region: Abi_2; cl01988
879088009309	Abi-like protein; Region: Abi_2; pfam07751
879088009310	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
879088009311	non-specific DNA binding site [nucleotide binding]; other site
879088009312	salt bridge; other site
879088009313	sequence-specific DNA binding site [nucleotide binding]; other site
879088009314	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
879088009315	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
879088009316	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
879088009317	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
879088009318	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
879088009319	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
879088009320	trmE is a tRNA modification GTPase; Region: trmE; cd04164
879088009321	G1 box; other site
879088009322	GTP/Mg2+ binding site [chemical binding]; other site
879088009323	Switch I region; other site
879088009324	G2 box; other site
879088009325	Switch II region; other site
879088009326	G3 box; other site
879088009327	G4 box; other site
879088009328	G5 box; other site
879088009329	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
879088009330	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
879088009331	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
879088009332	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
879088009333	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
879088009334	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
879088009335	tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362
879088009336	NADP binding site [chemical binding]; other site
879088009337	homodimer interface [polypeptide binding]; other site
879088009338	active site
879088009339	substrate binding site [chemical binding]; other site
879088009340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009341	D-galactonate transporter; Region: 2A0114; TIGR00893
879088009342	putative substrate translocation pore; other site
879088009343	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
879088009344	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
879088009345	metal binding site [ion binding]; metal-binding site
879088009346	dimer interface [polypeptide binding]; other site
879088009347	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
879088009348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
879088009349	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
879088009350	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
879088009351	metal binding site [ion binding]; metal-binding site
879088009352	dimer interface [polypeptide binding]; other site
879088009353	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088009354	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
879088009355	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664
879088009356	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
879088009357	Leucine-rich repeats; other site
879088009358	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088009359	Substrate binding site [chemical binding]; other site
879088009360	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
879088009361	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088009362	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088009363	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088009364	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088009365	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
879088009366	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
879088009367	Uncharacterized conserved protein [Function unknown]; Region: COG4198
879088009368	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
879088009369	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
879088009370	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
879088009371	putative ligand binding site [chemical binding]; other site
879088009372	putative NAD binding site [chemical binding]; other site
879088009373	putative catalytic site [active]
879088009374	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
879088009375	L-serine binding site [chemical binding]; other site
879088009376	ACT domain interface; other site
879088009377	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
879088009378	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
879088009379	catalytic residue [active]
879088009380	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009381	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088009382	putative substrate translocation pore; other site
879088009383	Transcriptional regulators [Transcription]; Region: MarR; COG1846
879088009384	MarR family; Region: MarR_2; pfam12802
879088009385	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
879088009386	dimer interface [polypeptide binding]; other site
879088009387	FMN binding site [chemical binding]; other site
879088009388	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
879088009389	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
879088009390	catalytic residues [active]
879088009391	beta-phosphoglucomutase; Region: bPGM; TIGR01990
879088009392	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
879088009393	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
879088009394	motif II; other site
879088009395	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
879088009396	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
879088009397	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
879088009398	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
879088009399	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
879088009400	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
879088009401	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
879088009402	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
879088009403	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
879088009404	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
879088009405	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
879088009406	putative NAD(P) binding site [chemical binding]; other site
879088009407	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
879088009408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088009409	dimer interface [polypeptide binding]; other site
879088009410	conserved gate region; other site
879088009411	putative PBP binding loops; other site
879088009412	ABC-ATPase subunit interface; other site
879088009413	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
879088009414	dimer interface [polypeptide binding]; other site
879088009415	conserved gate region; other site
879088009416	putative PBP binding loops; other site
879088009417	ABC-ATPase subunit interface; other site
879088009418	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
879088009419	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
879088009420	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
879088009421	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
879088009422	active site
879088009423	homodimer interface [polypeptide binding]; other site
879088009424	catalytic site [active]
879088009425	Transcriptional regulators [Transcription]; Region: PurR; COG1609
879088009426	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
879088009427	DNA binding site [nucleotide binding]
879088009428	domain linker motif; other site
879088009429	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
879088009430	putative dimerization interface [polypeptide binding]; other site
879088009431	putative ligand binding site [chemical binding]; other site
879088009432	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
879088009433	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
879088009434	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
879088009435	Coenzyme A binding pocket [chemical binding]; other site
879088009436	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009437	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088009438	putative substrate translocation pore; other site
879088009439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009440	Domain of unknown function (DUF718); Region: DUF718; cl01281
879088009441	rhamnulose-1-phosphate aldolase; Region: rhamnu_1P_ald; TIGR02624
879088009442	intersubunit interface [polypeptide binding]; other site
879088009443	active site
879088009444	Zn2+ binding site [ion binding]; other site
879088009445	L-rhamnose isomerase; Provisional; Region: PRK01076
879088009446	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
879088009447	N- and C-terminal domain interface [polypeptide binding]; other site
879088009448	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
879088009449	active site
879088009450	putative catalytic site [active]
879088009451	metal binding site [ion binding]; metal-binding site
879088009452	ATP binding site [chemical binding]; other site
879088009453	carbohydrate binding site [chemical binding]; other site
879088009454	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
879088009455	putative substrate translocation pore; other site
879088009456	Major Facilitator Superfamily; Region: MFS_1; pfam07690
879088009457	Cupin domain; Region: Cupin_2; pfam07883
879088009458	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
879088009459	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
879088009460	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
879088009461	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
879088009462	G-X-X-G motif; other site
879088009463	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
879088009464	RxxxH motif; other site
879088009465	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
879088009466	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
879088009467	ribonuclease P; Reviewed; Region: rnpA; PRK00499
879088009468	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399