-- dump date 20140619_134733 -- class Genbank::CDS -- table cds_note -- id note YP_001695603.1 pBt001-like protein YP_001695630.1 Includes: Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase); Pullulanase (EC 3.2.1.41) (1,4-alpha-D-glucan glucanohydrolase) (Alpha-dextrin endo-1,6-alpha-glucosidase) YP_001695676.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_001695743.1 similar to 41.9 kDa insecticidal toxin of strains 1593/2362/2317.3 YP_001695744.1 similar to larvicidal toxin 51 kDa protein of strains 1593/2362 YP_001695747.1 Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase) YP_001695777.1 Chromosomal replication initiator protein; ATPase involved in DNA replication initiation YP_001695778.1 Chromosomal replication initiator protein; ATPase involved in DNA replication initiation YP_001695779.1 Chromosomal replication initiator protein; ATPase involved in DNA replication initiation YP_001695780.1 Chromosomal replication initiator protein; ATPase involved in DNA replication initiation YP_001695781.1 binds the polymerase to DNA and acts as a sliding clamp YP_001695783.1 Recombinational DNA repair ATPase (RecF pathway) YP_001695784.1 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit YP_001695785.1 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit YP_001695793.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001695794.1 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis YP_001695797.1 Predicted transcriptional regulators YP_001695810.1 Uncharacterized protein conserved in bacteria YP_001695815.1 Arginine/lysine/ornithine decarboxylases YP_001695817.1 Uncharacterized protein conserved in bacteria YP_001695818.1 Uncharacterized protein conserved in bacteria YP_001695820.1 signal peptidase-like protein YP_001695821.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_001695822.1 methyltransferase YP_001695833.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001695838.1 Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase YP_001695863.1 Includes: Para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); Anthranilate synthase component II YP_001695880.1 similar to mitochondrial Aldehyde dehydrogenase YP_001695895.1 modulates transcription in response to the NADH/NAD(+) redox state YP_001695939.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_001695952.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001695973.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_001695974.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001695975.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001695979.1 Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC) YP_001695990.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001696065.1 Hypothetical 30.6 kDa protein in fumA 3'region precursor YP_001696077.1 initiation of sporulation, competence development; KO:K02035 YP_001696091.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_001696110.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001696136.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001696143.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001696144.1 proposed role in polysaccahride synthesis YP_001696146.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001696150.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_001696155.1 hpr; ScoC; MarR family; protease production regulatory protein YP_001696165.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001696166.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001696185.1 activates fatty acids by binding to coenzyme A YP_001696190.1 COG: Cytochrome c, mono- and diheme variants YP_001696195.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001696196.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001696197.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001696198.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001696200.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001696201.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001696209.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001696216.1 COG: Thiol-disulfide isomerase and thioredoxins YP_001696220.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001696222.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001696271.1 similar to Hydroxyacyl-coenzyme A dehydrogenase; converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001696288.1 KO:K00022 K01692 YP_001696289.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001696317.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001696342.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001696346.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001696352.1 similar to phosphate permease AF_1798 YP_001696359.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001696361.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001696375.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_001696384.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001696415.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001696416.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_001696417.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001696418.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001696419.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001696421.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001696427.1 COG: Sec-independent protein secretion pathway components YP_001696465.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001696469.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001696470.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001696473.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001696491.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_001696538.1 COG: AraC-type DNA-binding domain-containing proteins YP_001696595.1 similar to mitochondrial Long-chain specific acyl-CoA dehydrogenase YP_001696597.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell YP_001696618.1 Hypothetical 35.5 kDa protein in gldA 3'region YP_001696638.1 decatenates replicating daughter chromosomes YP_001696645.1 similar to mitochondrial Hydroxymethylglutaryl-CoA lyase YP_001696646.1 similar to mitochondrial Methylglutaconyl-CoA hydratase YP_001696647.1 KO:K01966 YP_001696653.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001696661.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however YP_001696703.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001696714.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001696718.1 KO:K01848 K01849 YP_001696721.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001696726.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001696727.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001696728.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001696736.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001696752.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001696753.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001696755.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001696757.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001696758.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001696795.1 COG: Rhs family protein YP_001696799.1 COG: Rhs family protein YP_001696878.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001696891.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001696942.1 KO:K01176 YP_001696951.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001696955.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_001696965.1 catalyzes the phosphorylation of NAD to NADP YP_001696979.1 similar to 2'-5' RNA ligase YP_001697020.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001697027.1 KO:K04034 YP_001697042.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001697045.1 similar to mitochondrial 3-hydroxyisobutyrate dehydrogenase YP_001697048.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001697080.1 involved in the transport of C4-dicarboxylates across the membrane YP_001697099.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_001697106.1 Hypothetical 52.8 kDa protein in TAR-I ttuC' 3'region YP_001697114.1 KO:K01582 YP_001697128.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein YP_001697130.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001697155.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001697163.1 COG: Protein required for the initiation of cell division YP_001697178.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin YP_001697193.1 Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase (UPRTase) YP_001697199.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_001697209.1 ATP-binding protein; initiation of sporulation, competence development; RBL00611 YP_001697217.1 COG: DNA-directed RNA polymerase, subunit K/omega YP_001697218.1 Includes: Phosphopantothenoylcysteine decarboxylase (PPCDC) (CoaC); Phosphopantothenate--cysteine ligase (Phosphopantothenoylcysteine synthase) (PPC synthetase) (PPCS) (CoaB) YP_001697220.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001697223.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001697244.1 catalyzes branch migration in Holliday junction intermediates YP_001697245.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_001697248.1 COG: (acyl-carrier-protein) S-malonyltransferase YP_001697256.1 KO:K03106 YP_001697261.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001697267.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001697268.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001697272.1 heat shock protein involved in degradation of misfolded proteins YP_001697273.1 heat shock protein involved in degradation of misfolded proteins YP_001697274.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_001697275.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001697276.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001697278.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001697279.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001697281.1 involved in type III protein export during flagellum assembly YP_001697288.1 COG: Uncharacterized protein, possibly involved in motility YP_001697290.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001697291.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001697294.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001697296.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001697297.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001697298.1 membrane protein involved in the flagellar export apparatus YP_001697299.1 positive regulator of class III flagellar genes YP_001697307.1 expressed in late exponential phase; controls the expression of genes coding cell surface proteins involved in chemotaxis, flagellar assembly, and autolysis YP_001697315.1 COG: Ribosome recycling factor YP_001697318.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001697323.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001697326.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001697330.1 Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase) YP_001697339.1 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme YP_001697346.1 KO:K02056 YP_001697370.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_001697378.1 catalyzes the formation of L-histidinol from L-histidinol phosphate YP_001697380.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001697394.1 Hypothetical 33.9 kDa protein in glnA 5'region YP_001697403.1 Hypothetical 50.9 kDa protein in katA 3'region YP_001697408.1 Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase YP_001697425.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001697454.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance YP_001697457.1 similar to HI1690 YP_001697476.1 KO:K01497 YP_001697477.1 Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase) YP_001697480.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001697530.1 COG: Predicted transcriptional regulators YP_001697594.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001697650.1 tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination YP_001697677.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001697688.1 COG: Rieske Fe-S protein YP_001697690.1 electron transport protein YP_001697696.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001697700.1 Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase); KO:K03524 K01947 YP_001697720.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001697721.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001697722.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001697748.1 COG: Transposase and inactivated derivatives YP_001697751.1 Includes: GTP cyclohydrolase-2 (GTP cyclohydrolase II); 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) YP_001697755.1 COG0406 YP_001697758.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001697784.1 Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase) YP_001697785.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_001697804.1 ethanolamine utilization protein EutA YP_001697814.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001697816.1 KO:K01299 YP_001697828.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_001697837.1 similar to MJ0796 YP_001697853.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001697855.1 catalyzes the formation of pyruvate from serine YP_001697866.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_001697901.1 KO:K01473 YP_001697902.1 KO:K01474 YP_001697927.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001697931.1 COG: Transcriptional regulator YP_001697934.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001698036.1 Includes: N-acetylglucosamine permease IIC component (PTS system N-acetylglucosamine-specific EIIC component); N-acetylglucosamine-specific phosphotransferase enzyme IIB component (PTS system N-acetylglucosamine-specific EIIB component); N-acetylglucosamine-specific phosphotransferase enzyme IIA component (PTS system N-acetylglucosamine-specific EIIA component) YP_001698117.1 decatenates replicating daughter chromosomes YP_001698202.1 similar to AF_0266 YP_001698207.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever YP_001698283.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_001698296.1 COG: Predicted transcriptional regulators YP_001698346.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001698362.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001698367.1 catalyzes the formation of fumarate from aspartate YP_001698371.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001698421.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae YP_001698443.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001698463.1 similar to mitochondrial Serine protease HTRA2 YP_001698472.1 COG: DNA-directed RNA polymerase specialized sigma subunit, sigma24-like YP_001698516.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001698522.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001698523.1 Hypothetical 45.4 kDa protein in snaA-snaB intergenic region YP_001698556.1 COG: L-lactate permease YP_001698557.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001698560.1 multicopy suppressor of dominant negative ftsH mutations YP_001698563.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001698606.1 similar to the chloroplast 3-oxoacyl-[acyl-carrier-protein] reductase YP_001698619.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001698620.1 activates fatty acids by binding to coenzyme A YP_001698625.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001698627.1 similar to mitochondrial Acyl-CoA dehydrogenase family member 9 YP_001698629.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001698630.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration YP_001698666.1 similar to MJ0412 YP_001698667.1 similar to HI0355 YP_001698670.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001698681.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001698698.1 Catalyzes the conversion of citrate to isocitrate YP_001698711.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_001698718.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001698725.1 Hypothetical 39.9 kDa protein in amylase 3'region YP_001698736.1 similar to methyltransferase Mb3374 YP_001698812.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress YP_001698851.1 COG: Glycopeptide antibiotics resistance protein YP_001698853.1 COG: O-Methyltransferase involved in polyketide biosynthesis YP_001698866.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001698927.1 COG: Integral membrane protein possibly involved in chromosome condensation YP_001698947.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_001698952.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001698990.1 Hypothetical 27.4 kDa protein in cobO 3'region YP_001699007.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001699008.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001699012.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001699058.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001699062.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_001699076.1 COG: Glycosyltransferases involved in cell wall biogenesis YP_001699080.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001699086.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_001699113.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001699125.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001699127.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001699129.1 COG: Exonuclease VII small subunit YP_001699131.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell YP_001699132.1 Includes: Methylenetetrahydrofolate dehydrogenase; Methenyltetrahydrofolate cyclohydrolase YP_001699154.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001699169.1 COG: Predicted transcriptional regulators YP_001699173.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001699223.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_001699224.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_001699245.1 similar to aq_812 YP_001699262.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001699270.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001699284.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001699295.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001699299.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001699303.1 involved in the transport of C4-dicarboxylates across the membrane YP_001699314.1 COG: Cytochrome c, mono- and diheme variants YP_001699320.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001699323.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001699326.1 COG: Cytidine deaminase YP_001699336.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001699408.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001699409.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001699413.1 KO:K01463 YP_001699417.1 similar to mitochondrial Trans-2-enoyl-CoA reductase YP_001699441.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001699444.1 Initiates the rapid degradation of small, acid-soluble proteins during spore germination YP_001699453.1 COG: SAM-dependent methyltransferases YP_001699460.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_001699462.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001699504.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001699519.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001699525.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001699546.1 involved in the peptidyltransferase reaction during translation YP_001699552.1 blocks the formation of polar Z-ring septums YP_001699555.1 functions in MreBCD complex in some organisms YP_001699565.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001699566.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001699568.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001699570.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001699577.1 binds and unfolds substrates as part of the ClpXP protease YP_001699594.1 KO:K06310 YP_001699633.1 similar to HI1721 YP_001699650.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001699651.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001699660.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001699672.1 similar to slr1673 YP_001699682.1 similar to mitochondrial D-lactate dehydrogenase YP_001699697.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001699707.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001699712.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_001699716.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001699717.1 Converts isocitrate to alpha ketoglutarate YP_001699745.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_001699746.1 catalyzes the formation of L-histidinol from L-histidinol phosphate YP_001699774.1 similar to Lmo0432 YP_001699785.1 Includes: Glutamate N-acetyltransferase (Ornithine acetyltransferase) (Ornithine transacetylase) (OATase); Amino-acid acetyltransferase (N-acetylglutamate synthase) (AGS) YP_001699787.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001699792.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_001699796.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001699802.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001699822.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_001699832.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001699841.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001699866.1 Includes: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase); 2-oxoglutarate decarboxylase (Alpha-ketoglutarate decarboxylase) (KDC) YP_001699870.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001699874.1 similar to chloroplast Protease Do-like 1 YP_001699875.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001699876.1 COG: ABC-type Fe3+-hydroxamate transport system, periplasmic component YP_001699880.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001699885.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_001699918.1 involved in manganese homeostasis; activates the transcription of the mntABCD operon YP_001699937.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001700009.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001700011.1 catalyzes resistance to fosfomycin by the addition of a thiol cofactor YP_001700048.1 28 kDa outer membrane protein; 28 kDa cytosoluble protein; CP28 YP_001700091.1 COG0454 YP_001700104.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001700114.1 COG: DNA-directed RNA polymerase specialized sigma subunit, sigma24-like factor YP_001700139.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001700146.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial YP_001700157.1 COG: Ribosomal protein L13 YP_001700162.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001700163.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001700168.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001700170.1 COG: Ribosomal protein L30/L7E YP_001700172.1 binds 5S rRNA along with protein L5 and L25 YP_001700177.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001700181.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001700185.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001700188.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001700198.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001700200.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001700201.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001700204.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001700209.1 binds directly to 23S ribosomal RNA YP_001700212.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001700216.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001700218.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001700219.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001700222.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001700244.1 ABC-type branched-chain amino acid transport systems, periplasmic component; KO:K01999 YP_001700247.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_001700276.1 KO:K03407 YP_001700285.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001700294.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001700337.1 unwinds double stranded DNA YP_001700338.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001700354.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001700359.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates