-- dump date   	20140619_135009
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_419365.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_419369.1	conserved in bacteria
YP_419371.1	similar to the N-terminal domain of Lon protease
YP_419375.1	related FAD-dependent oxidoreductase
YP_419379.1	related protein
YP_419383.1	EC 35425
YP_419388.1	msp1
YP_419390.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_419391.1	periplasmic protein
YP_419392.1	required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA
YP_419395.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_419398.1	NodU family
YP_419399.1	conserved in bacteria
YP_419403.1	related Zn-dependent dehydrogenase
YP_419404.1	predicted exonuclease
YP_419406.1	involved in methicillin resistance
YP_419415.1	apparently involved in regulation of cell wall biogenesis
YP_419417.1	involved in regulation of cell wall biogenesis
YP_419420.1	involved in cell wall biogenesis
YP_419423.1	ATPase and permease components
YP_419425.1	bifunctional sugar kinase/adenylyltransferase
YP_419436.1	dehydrogenase (E1) component, eukaryotic type, alpha subunit
YP_419437.1	isoleucine patch superfamily
YP_419438.1	apparently involved in regulation of cell wall biogenesis
YP_419441.1	apparently involved in regulation of cell wall biogenesis
YP_419445.1	related hydrolase of the PHP family
YP_419446.1	undetermined role; similar to CarB protein but much smaller
YP_419448.1	eIF-2Bgamma/eIF-2Bepsilon
YP_419453.1	related to short-chain alcohol dehydrogenase
YP_419459.1	involved in cell wall biogenesis
YP_419463.1	involved in de novo purine biosynthesis
YP_419473.1	involved in cell wall biogenesis
YP_419474.1	apparently involved in regulation of cell wall biogenesis
YP_419475.1	isoleucine patch superfamily
YP_419478.1	involved in cell wall biogenesis
YP_419484.1	eIF-2Bgamma/eIF-2Bepsilon
YP_419488.1	involved in cell wall biogenesis
YP_419497.1	related to short-chain alcohol dehydrogenase
YP_419505.1	involved in cell wall biogenesis
YP_419512.1	involved in cell wall biogenesis
YP_419516.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_419518.1	involved in D-alanine export
YP_419520.1	eIF-2Bgamma/eIF-2Bepsilon
YP_419525.1	catalyzes the phosphorylation of NAD to NADP
YP_419530.1	homolog of microcin C7 resistance protein MccF
YP_419531.1	consists of N-terminal helix-turn-helix domain and C-terminal shikimate kinase-like domain which may bind benzoyl-CoA; controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate
YP_419532.1	NADH-binding (51 kD) subunit
YP_419535.1	alpha/beta hydrolase superfamily
YP_419537.1	cleaves the ring of 2,3-dihydro-2,3-dihydroxybenzoyl-CoA forming 6-hydroxy-3-hexenoyl-CoA
YP_419539.1	root-type isozyme, chloroplast precursor
YP_419541.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_419542.1	alpha and beta subunits
YP_419543.1	Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
YP_419545.1	ATPase component
YP_419546.1	permease component
YP_419549.1	periplasmic component/domain
YP_419557.1	conserved in bacteria
YP_419561.1	involved in molybdopterin and thiamine biosynthesis family 2
YP_419565.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_419566.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth
YP_419567.1	conserved in bacteria
YP_419568.1	conserved in bacteria
YP_419571.1	MnhD subunit
YP_419578.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_419579.1	the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli
YP_419584.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_419591.1	involved in cell wall biogenesis
YP_419592.1	homolog of Cu resistance protein CopC
YP_419594.1	periplasmic component
YP_419602.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_419607.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_419613.1	conserved in bacteria
YP_419619.1	related to aryl-alcohol dehydrogenase
YP_419620.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_419621.1	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway
YP_419622.1	catalyzes the formation of protocatechuate from 4-hydroxybenzoate
YP_419638.1	catalyzes the ATP-dependent transport of cobalt
YP_419639.1	periplasmic cobalt binding component of the cobalt transport system
YP_419640.1	permease component CbiQ and related transporters
YP_419641.1	ATPase component
YP_419650.1	This protein performs the mismatch recognition step during the DNA repair process
YP_419652.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_419655.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_419668.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_419675.1	conserved in bacteria
YP_419676.1	permease component
YP_419681.1	Heat shock protein 33 homolog, HSP33
YP_419686.1	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins
YP_419690.1	conserved in bacteria
YP_419692.1	auxiliary component
YP_419693.1	involved in resistance to organic solvents, periplasmic component
YP_419694.1	involved in resistance to organic solvents, ATPase component
YP_419695.1	involved in resistance to organic solvents, permease component
YP_419697.1	regulator of sigma subunit
YP_419700.1	alpha/beta hydrolase superfamily
YP_419703.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_419707.1	DNA invertase Pin homolog
YP_419750.1	involved in colicin uptake
YP_419758.1	tail component
YP_419761.1	ISmag1; similar to IS5 family
YP_419765.1	ISmag11,orf2; similar to IS66 family
YP_419766.1	ISmag11,orf3; similar to IS66 family
YP_419767.1	ISmag11,orf3; similar to IS66 family
YP_419768.1	ISmag11,orf2; similar to IS66 family
YP_419769.1	ISmag11,orf1; similar to IS66 family
YP_419771.1	ISmag5; similar to IS5 family
YP_419774.1	ISmag2; similar to IS4 family
YP_419778.1	LmbE homolog
YP_419787.1	periplasmic component
YP_419791.1	related to MYG1 family
YP_419797.1	involved in resistance to organic solvents, auxiliary component
YP_419800.1	periplasmic component/domain
YP_419801.1	regulator of sigma subunit
YP_419847.1	containing caspase domain
YP_419858.1	gamma/tau subunits
YP_419861.1	membrane protein involved in the flagellar export apparatus
YP_419862.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_419863.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_419864.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_419865.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_419866.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_419871.1	related to molybdopterin-biosynthesis enzyme MoeA
YP_419872.1	including oxidative damage repair enzyme
YP_419876.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_419885.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_419891.1	LPS heptosyltransferase
YP_419894.1	typically selenocysteine-containing
YP_419897.1	periplasmic component
YP_419898.1	contain duplicated ATPase
YP_419899.1	permease component
YP_419900.1	periplasmic component
YP_419903.1	mostly Fe transport
YP_419906.1	conserved in bacteria
YP_419914.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_419916.1	containing a CheY-like receiver domain and an HD-GYP domain
YP_419918.1	EC 2611
YP_419920.1	SEL1 subfamily
YP_419925.1	4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction
YP_419926.1	conserved in bacteria
YP_419931.1	conserved in bacteria
YP_419937.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
YP_419943.1	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase
YP_419950.2	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_419951.1	involved in resistance to organic solvents, ATPase component
YP_419958.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_419960.1	alpha/beta hydrolase superfamily
YP_419967.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_419969.1	containing LysM domain
YP_419971.1	Converts isocitrate to alpha ketoglutarate
YP_419973.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_419978.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_419979.1	forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella
YP_419980.1	component FliQ
YP_419981.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_419982.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_419984.1	containing caspase domain
YP_419985.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_419986.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_419987.1	alpha/beta hydrolase superfamily
YP_419991.1	involved in type III protein export during flagellum assembly
YP_419992.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_419994.1	involved in ubiquinone/menaquinone biosynthesis
YP_419995.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_419998.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_419999.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_420000.1	binds the polymerase to DNA and acts as a sliding clamp
YP_420001.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_420002.1	negatively supercoils closed circular double-stranded DNA
YP_420003.1	ISmag6,orf1; similar to IS3 family
YP_420004.1	ISmag6,orf2; similar to IS3 family
YP_420009.1	ISmag7,orf1; similar to IS3 family
YP_420010.1	ISmag6,orf2; similar to IS3 family
YP_420011.1	ISmag6,orf2,partial; similar to IS3 family
YP_420012.1	ISmag6,orf1; similar to IS3 family
YP_420014.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_420015.1	containing a CheY-like receiver domain and an HD-GYP domain
YP_420027.1	msp3
YP_420039.1	subunits alpha and beta
YP_420044.1	involved in DNA uptake
YP_420045.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_420048.1	conserved in bacteria
YP_420050.1	SPINDLY family
YP_420056.1	FOG: TPR repeat
YP_420060.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_420065.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_420066.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_420071.1	SPINDLY family
YP_420074.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_420080.1	involved in regulation of cell wall biogenesis
YP_420083.1	NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate
YP_420084.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_420086.1	FOG: CheY-like receiver
YP_420092.1	containing a membrane domain
YP_420095.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_420107.1	related to short-chain alcohol dehydrogenase
YP_420111.1	Essential for recycling GMP and indirectly, cGMP
YP_420126.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine
YP_420129.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_420131.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein
YP_420132.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
YP_420137.1	ATPase component
YP_420141.1	bifunctional sugar kinase/adenylyltransferase
YP_420142.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
YP_420148.1	catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP
YP_420156.1	apparently involved in regulation of cell wall biogenesis
YP_420161.1	eIF-2Bgamma/eIF-2Bepsilon
YP_420169.1	catechol pathway
YP_420170.1	catechol pathway
YP_420171.1	large permease component
YP_420173.1	periplasmic component
YP_420176.1	possibly involved in utilization of glycolate and propanediol
YP_420180.1	conserved in bacteria
YP_420182.1	conserved in bacteria
YP_420184.1	putative cysteine protease
YP_420197.1	Valyl-tRNA synthetase; Leucyl-tRNA synthetase
YP_420198.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_420202.1	conserved in bacteria
YP_420204.1	phbC homolog
YP_420205.1	phbA homolog
YP_420206.1	phbB homolog
YP_420208.1	containing a CheY-like receiver domain and an HD-GYP domain
YP_420209.1	mostly Fe transport
YP_420210.1	Osmosensitive K+ channel histidine kinase
YP_420211.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_420213.1	XdhC/CoxF family
YP_420214.1	possibly involved in aromatic compounds catabolism
YP_420215.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_420221.1	regulator of disulfide bond formation
YP_420230.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_420238.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_420241.1	isoleucine patch superfamily
YP_420243.1	related to short-chain alcohol dehydrogenase
YP_420249.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
YP_420253.1	periplasmic component
YP_420254.1	fused permease components
YP_420256.1	large permease component
YP_420257.1	small permease component
YP_420258.1	periplasmic component
YP_420265.1	related to metalloendopeptidase
YP_420273.1	ISmag7,orf2,partial; similar to IS3 family
YP_420274.1	ISmag7,orf1; similar to IS3 family
YP_420277.1	ISmag7,orf1; similar to IS3 family
YP_420282.1	consists of a Zn-ribbon and ATP-cone domains
YP_420289.1	Site-specific recombinase XerC
YP_420302.1	probably involved in high-affinity Fe2+ transport
YP_420303.1	probably involved in high-affinity Fe2+ transport
YP_420312.1	ISmag3; similar to IS1111 family
YP_420317.1	similar to mms6
YP_420321.1	conserved in bacteria
YP_420326.1	contain C-terminal PDZ domain
YP_420327.1	links inner and outer membranes
YP_420328.1	involved in cell morphogenesis
YP_420332.1	typically periplasmic, contain C-terminal PDZ domain; Predicted permease
YP_420340.1	related to eukaryotic diacylglycerol kinase
YP_420365.1	typically periplasmic, contain C-terminal PDZ domain
YP_420367.1	typically periplasmic, contain C-terminal PDZ domain
YP_420404.1	ISmag8; similar to IS1 family
YP_420408.1	ISmag6,orf1; similar to IS3 family
YP_420409.1	ISmag6,orf2; similar to IS3 family
YP_420411.1	containing a CheY-like receiver domain and an HD-GYP domain
YP_420412.1	periplasmic component
YP_420419.1	flavoprotein subunit
YP_420425.1	ATPase component
YP_420426.1	permease component
YP_420428.1	involved in D-alanine export
YP_420429.1	including oxidative damage repair enzyme
YP_420430.1	Glycosyltransferase involved in cell wall biogenesis
YP_420433.1	ATPase component
YP_420434.1	permease component
YP_420435.1	apparently involved in regulation of cell wall biogenesis
YP_420436.1	related to galactokinase and mevalonate kinase
YP_420440.1	Nucleoside-diphosphate-sugar epimerase
YP_420441.1	involved in cell wall biogenesis
YP_420443.1	involved in cell wall biogenesis
YP_420445.1	involved in cell wall biogenesis
YP_420457.1	containing CBS domain
YP_420463.1	arginase family
YP_420467.1	containing a membrane domain
YP_420468.1	periplasmic component
YP_420470.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_420480.1	(antagonist of anti-sigma factor)
YP_420485.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_420488.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_420547.1	involved in colicin uptake
YP_420555.1	tail component
YP_420560.1	DNA invertase Pin homolog
YP_420564.1	DNA invertase Pin homolog
YP_420566.1	catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin; involved in methanogenesis from carbon dioxide
YP_420571.1	including glyoxylase
YP_420574.1	containing a CheY-like receiver domain and an HD-GYP domain
YP_420577.1	EAL and a GGDEF domain; containing a membrane domain
YP_420588.1	periplasmic component
YP_420591.1	involved in cation transport
YP_420596.1	NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_420598.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_420599.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_420602.1	conserved in bacteria
YP_420618.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_420620.1	periplasmic component
YP_420622.1	iso-2
YP_420628.1	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
YP_420631.1	involved in heme utilization or adhesion
YP_420636.1	related to pyridoxine 5'-phosphate oxidase
YP_420638.1	adhesin AidA
YP_420642.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_420643.1	contains nucleotidyltransferase and I-patch acetyltransferase domains
YP_420644.1	EAL and a GGDEF domain
YP_420648.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_420655.1	permease component
YP_420656.1	periplasmic component
YP_420660.2	ISmag1; similar to IS5 family
YP_420670.1	including oxidative damage repair enzyme
YP_420671.1	possibly involved in tellurium resistance
YP_420677.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_420684.1	alpha/beta hydrolase superfamily
YP_420686.1	periplasmic component
YP_420687.1	ATPase component
YP_420688.1	duplicated permease component
YP_420693.1	conserved in bacteria
YP_420696.1	conserved in bacteria
YP_420698.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_420705.1	conserved in bacteria
YP_420707.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_420708.1	containing a CheY-like receiver domain and a GGDEF domain
YP_420710.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_420715.1	conserved in bacteria
YP_420718.1	periplasmic component
YP_420719.1	containing a membrane domain, an EAL and a GGDEF domain
YP_420721.1	related to arylsulfate sulfotransferase involved in siderophore biosynthesis
YP_420728.1	involved in cell wall biogenesis
YP_420733.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_420735.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_420736.1	permease component
YP_420737.1	permease component
YP_420738.1	periplasmic component
YP_420739.1	MocR family; containing a DNA-binding HTH domain and an aminotransferase domain and their eukaryotic ortholog
YP_420743.1	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis
YP_420745.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_420754.1	contains TPR repeats
YP_420775.1	periplasmic component/domain
YP_420777.1	EAL and a GGDEF domain
YP_420793.1	(EC 273-)
YP_420811.1	conserved in bacteria
YP_420828.1	ATPase and permease component
YP_420830.1	containing a CheY-like receiver domain and a GGDEF domain
YP_420838.1	ATPase component
YP_420839.1	ATPase component
YP_420840.1	permease component
YP_420841.1	periplasmic component
YP_420847.1	middle subunit CoxM/CutM homolog
YP_420854.1	Site-specific recombinase XerD
YP_420890.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_420902.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_420903.1	PurS component
YP_420904.1	links inner and outer membranes
YP_420906.1	epsilon subunit and related 3'-5' exonuclease
YP_420910.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_420913.1	quinone reductase and related Zn-dependent oxidoreductase
YP_420923.1	ATP-binding subunit
YP_420931.1	functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe
YP_420932.1	functions with NifN to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe
YP_420937.1	nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; in R. etli there are three essentially identical copies of nifH which are actively expressed during symbiosis
YP_420947.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_420953.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_420962.1	related to short-chain alcohol dehydrogenase
YP_420967.1	stimulates sugar fermentation
YP_420972.1	conserved in bacteria
YP_420974.1	Involved in ubiquinone biosynthesis
YP_420975.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_420978.1	conserved in bacteria
YP_420979.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_421011.1	HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits
YP_421012.1	Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2
YP_421019.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_421031.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_421035.1	permease component
YP_421036.1	ATPase component
YP_421037.1	ATPase component
YP_421040.1	delta subunit
YP_421046.1	catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine
YP_421069.1	conserved in bacteria
YP_421071.1	typically periplasmic, contain C-terminal PDZ domain
YP_421088.1	ISmag6,orf1; similar to IS3 family
YP_421089.1	ISmag6,orf2; similar to IS3 family
YP_421095.1	ISmag1; similar to IS5 family
YP_421150.2	catalyzes the formation of L-tryptophan from indole and L-serine
YP_421155.1	isoleucine patch superfamily
YP_421156.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_421176.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_421184.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_421185.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_421194.1	glutaredoxin family
YP_421221.1	ATPase component
YP_421222.1	permease component
YP_421223.1	periplasmic components
YP_421226.1	periplasmic components
YP_421227.1	permease component
YP_421228.1	ATPase component
YP_421255.1	conserved in bacteria
YP_421272.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_421273.1	ATPase chain B
YP_421274.1	c chain
YP_421277.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_421281.1	EAL and a GGDEF domain
YP_421286.1	ISmag6,orf1; similar to IS3 family
YP_421287.1	ISmag6,orf2; similar to IS3 family
YP_421301.1	conserved in bacteria
YP_421308.1	containing a CheY-like receiver domain and a GGDEF domain
YP_421309.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_421329.1	containing a CheY-like receiver domain and a methylesterase domain
YP_421334.1	EAL and a GGDEF domain
YP_421340.1	permease components
YP_421341.1	permease components
YP_421342.1	periplasmic component
YP_421345.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_421349.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_421372.1	periplasmic component
YP_421373.1	permease component
YP_421374.1	permease component
YP_421375.1	ATPase component
YP_421385.1	XdhC/CoxF family
YP_421388.1	catalyzes the conversion of ferulic acid to feruloyl-CoA
YP_421391.1	permease component
YP_421392.1	permease components
YP_421393.1	periplasmic component
YP_421394.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_421404.1	ISmag6,orf2; similar to IS3 family
YP_421405.1	ISmag6,orf1; similar to IS3 family
YP_421407.1	methylase subunits
YP_421408.1	ISmag1; similar to IS5 family
YP_421425.1	DNA invertase Pin homolog
YP_421436.1	3'-5' exonuclease of DNA polymerase III
YP_421437.1	Zn-ribbon and ATP-cone domains
YP_421451.1	related to short-chain alcohol dehydrogenase
YP_421452.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_421453.1	required for colicin V production
YP_421454.2	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_421456.1	ATPase component
YP_421457.1	permease component
YP_421461.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_421464.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_421466.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_421469.1	related to short-chain alcohol dehydrogenase
YP_421470.1	carries the fatty acid chain in fatty acid biosynthesis
YP_421471.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_421473.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_421477.1	glutamine amidotransferase domain
YP_421478.1	synthetase domain
YP_421491.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_421502.1	HSP70-class ATPase domain
YP_421511.1	yjgF family
YP_421513.1	related to short-chain alcohol dehydrogenase
YP_421530.1	subunit 3
YP_421531.1	involved in the insertion of copper into subunit I of cytochrome C oxidase
YP_421532.1	subunit 1
YP_421533.1	subunit 2
YP_421557.1	conserved in bacteria
YP_421561.1	ISmag1; similar to IS5 family
YP_421562.1	some contain LysM/invasin domains
YP_421564.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_421565.1	NCAIR mutase
YP_421572.1	beta subunit (hemoprotein)
YP_421573.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_421574.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_421586.1	cytochrome oxidase assembly factor
YP_421587.1	involved in biogenesis of respiratory and photosynthetic systems
YP_421590.1	subunit 1
YP_421592.1	subunit 2
YP_421594.1	permease and ATPase components
YP_421598.1	family 3
YP_421603.1	SEL1 subfamily
YP_421605.1	catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA
YP_421610.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_421615.1	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_421617.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_421619.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_421622.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_421624.1	RecF pathway
YP_421640.1	EAL and a GGDEF domain
YP_421647.1	AAA-type ATPase, and DNA-binding domains
YP_421657.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif
YP_421664.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_421669.1	G3E family
YP_421679.1	eukaryotic type, alpha subunit
YP_421680.1	catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase
YP_421684.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_421685.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_421702.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_421703.1	Zn-ribbon and ATP-cone domains
YP_421711.1	pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient
YP_421715.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_421716.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_421718.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_421722.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_421726.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
YP_421729.1	nitrogen specific
YP_421730.1	AAA-type ATPase, and DNA-binding domains
YP_421732.1	AAA-type ATPase, and DNA-binding domains
YP_421733.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_421735.1	Stimulates the elongation of poly(A) tails
YP_421740.1	N-terminal double-glycine peptidase domain
YP_421745.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_421746.1	cyclophilin family
YP_421747.1	cyclophilin family
YP_421755.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
YP_421812.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_421819.1	related to diketogulonate reductase
YP_421828.1	superfamily II helicase
YP_421830.1	catalyzes branch migration in Holliday junction intermediates
YP_421832.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_421845.2	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
YP_421849.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_421850.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_421851.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_421855.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_421858.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_421859.1	Catalyzes the phosphorylation of UMP to UDP
YP_421860.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_421861.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_421862.1	D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm
YP_421867.1	SPINDLY family
YP_421870.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain
YP_421876.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_421877.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_421879.1	AAA+ superfamily
YP_421883.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_421884.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_421892.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_421899.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_421906.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_421907.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_421913.1	catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit
YP_421926.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_421932.2	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_421933.1	MAPEG superfamily
YP_421935.1	involved in lipoprotein release
YP_421944.1	Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate
YP_421948.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_421950.1	related to short-chain alcohol dehydrogenase
YP_421952.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_421953.1	related to short-chain alcohol dehydrogenase
YP_421958.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_421959.1	converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation
YP_421960.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_421965.1	permease components
YP_421966.1	permease component
YP_421968.1	ATPase component
YP_421969.1	possibly involved in aromatic compounds catabolism
YP_421973.1	SPINDLY family
YP_421974.1	involved in thiamine biosynthesis
YP_421976.1	subunit RnfA
YP_421977.1	Nitrogen fixation protein rnfB
YP_421978.1	Nitrogen fixation protein rnfC
YP_421980.1	subunit RnfG
YP_421981.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_421984.1	membrane components
YP_421985.1	permease component II
YP_421986.1	permease component I
YP_421987.1	ATPase components
YP_421989.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
YP_421995.1	beta subunit
YP_421996.1	alpha subunit
YP_422005.1	Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
YP_422009.1	sigma24 homolog
YP_422010.1	conserved in bacteria
YP_422012.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_422013.1	beta subunit
YP_422014.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_422016.1	conserved in bacteria
YP_422022.1	regulator of sigma subunit
YP_422027.1	contains double-stranded beta-helix domain
YP_422029.1	for formate dehydrogenase activity
YP_422030.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway
YP_422034.1	typically selenocysteine-containing
YP_422038.1	isoleucine patch superfamily
YP_422040.1	related to short-chain alcohol dehydrogenase
YP_422043.1	conserved in bacteria
YP_422048.1	conserved in bacteria
YP_422051.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
YP_422052.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
YP_422053.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_422054.1	involved in formation of periplasmic nitrate reductase
YP_422056.1	EAL and a GGDEF domain
YP_422057.1	Zn-finger, probably nucleic-acid-binding
YP_422059.1	catalyzes the carboxylation of D-ribulose 1,5-bisphosphate in carbon dioxide fixation
YP_422061.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_422064.1	alpha/beta hydrolase superfamily
YP_422065.1	fusion of thiS and thiG; functions in thiamine (vitamin B1) biosynthesis
YP_422068.1	periplasmic component
YP_422069.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_422071.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_422098.1	family 4 of glycosyl hydrolase
YP_422103.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_422104.1	conserved in bacteria
YP_422108.1	Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis
YP_422109.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_422114.1	yjgF family
YP_422116.1	possibly involved in aromatic compounds catabolism
YP_422123.1	alpha/beta hydrolase superfamily
YP_422128.1	involved in lipoprotein release, permease component
YP_422129.1	ATPase component
YP_422130.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_422135.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_422137.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422138.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422139.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_422140.1	chain K
YP_422141.1	chain J
YP_422142.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422143.1	chain H
YP_422144.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422145.1	part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase
YP_422147.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422148.1	Catalyzes the transfer of electrons from NADH to quinone
YP_422149.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_422150.1	chain A
YP_422153.1	bacterial type
YP_422154.1	binds and unfolds substrates as part of the ClpXP protease
YP_422156.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_422166.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_422170.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_422176.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_422179.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_422183.2	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_422187.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
YP_422190.1	catechol pathway
YP_422199.2	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_422201.1	conserved in bacteria
YP_422203.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_422204.1	SPINDLY family
YP_422205.1	related to short-chain alcohol dehydrogenase
YP_422212.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_422225.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_422229.1	Represses a number of genes involved in the response to DNA damage
YP_422235.1	permease component
YP_422236.1	permease components
YP_422237.1	periplasmic component
YP_422238.1	catechol pathway
YP_422244.1	middle subunit CoxM/CutM homolog
YP_422245.1	small subunit CoxS/CutS homolog
YP_422247.1	1,4-beta-N-acetylmuramidase
YP_422252.1	Old Yellow Enzyme family
YP_422267.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_422291.1	light-regulated signal transduction histidine kinase
YP_422335.1	Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein
YP_422355.1	Pyrroloquinoline quinone biosynthesis protein E
YP_422382.1	PP-loop ATPase domain
YP_422387.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_422397.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_422400.1	frataxin homolog
YP_422401.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_422410.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_422415.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_422418.1	typically periplasmic, contain C-terminal PDZ domain
YP_422427.1	Type II secretory pathway
YP_422428.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_422432.1	in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme
YP_422433.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
YP_422456.1	EAL and a GGDEF domain
YP_422469.1	TPR repeat
YP_422470.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_422471.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_422472.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_422474.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_422476.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_422478.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_422479.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_422481.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_422482.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_422483.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_422484.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_422486.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_422487.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_422488.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_422489.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_422490.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_422491.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_422492.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_422493.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_422494.2	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_422495.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_422496.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_422497.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_422498.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_422501.1	typically periplasmic, contain C-terminal PDZ domain
YP_422503.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_422504.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_422505.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_422506.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_422509.1	Modulates Rho-dependent transcription termination
YP_422510.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_422511.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_422514.1	ISmag7,orf2; similar to IS3 family
YP_422515.1	ISmag7,orf1; similar to IS3 family
YP_422532.1	DNA invertase Pin homolog
YP_422536.1	Old Yellow Enzyme family
YP_422541.1	Involved in the tartrate degradation pathway
YP_422542.1	Involved in the tartrate degradation pathway
YP_422550.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_422553.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_422556.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_422557.2	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate
YP_422562.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_422574.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_422579.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_422581.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_422582.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_422588.1	conserved in bacteria
YP_422592.1	alpha subunit
YP_422593.1	beta subunit
YP_422597.1	Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
YP_422609.1	alpha/beta hydrolase superfamily
YP_422625.1	ISmag6,orf1; similar to IS3 family
YP_422626.1	ISmag6,orf2; similar to IS3 family
YP_422627.1	ISmag7,orf2,partial; similar to IS3 family
YP_422628.1	ISmag7,orf1; similar to IS3 family
YP_422633.1	DNA invertase Pin homolog
YP_422637.1	Multidrug resistance efflux pump
YP_422661.1	ISmag1; similar to IS5 family
YP_422668.1	Old Yellow Enzyme family
YP_422672.1	DNA invertase Pin homolog
YP_422679.1	ISmag9,orf1; similar to IS1 family
YP_422681.1	ISmag11,orf1; similar to IS66 family
YP_422682.1	ISmag11,orf2; similar to IS66 family
YP_422683.1	ISmag11,orf3; similar to IS66 family
YP_422685.1	ISmag9,orf2; similar to IS1 family
YP_422686.1	ISmag10,orf1; similar to IS3 family
YP_422687.1	ISmag10,orf2; similar to IS3 family
YP_422688.1	ISmag11,orf3; similar to IS66 family
YP_422689.1	ISmag11,orf2; similar to IS66 family
YP_422690.1	ISmag11,orf1; similar to IS66 family
YP_422691.1	ISmag10,orf3; similar to IS3 family
YP_422705.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_422706.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_422713.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_422716.1	antagonist of anti-sigma factor
YP_422727.1	shows similarity to CbiX(S)
YP_422735.1	gamma subunit
YP_422738.1	unknown function
YP_422743.1	MFS superfamily
YP_422751.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_422756.1	hoxF homolog
YP_422757.1	hoxU homolog
YP_422758.1	hoxY homolog
YP_422759.1	hoxH homolog
YP_422760.1	hoxW homolog
YP_422768.1	PAS/PAC domain
YP_422769.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_422786.1	PAS/PAC domain
YP_422795.1	DNA invertase Pin homolog
YP_422804.1	alpha/beta hydrolase superfamily
YP_422827.1	AAA-type ATPase, and DNA binding domains
YP_422829.1	K+/H+ antiporter
YP_422836.1	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group
YP_422841.1	sigma24 homolog
YP_422855.1	typically periplasmic, contain C-terminal PDZ domain
YP_422856.1	part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod
YP_422857.1	required for the assembly of the flagellar basal body P-ring; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagellum
YP_422858.1	makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella
YP_422861.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum
YP_422871.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_422872.2	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_422875.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_422876.1	functions in MreBCD complex in some organisms
YP_422877.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_422895.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_422898.1	MFS superfamily
YP_422904.1	typically selenocysteine-containing
YP_422910.1	mostly Fe transport
YP_422919.1	forms a direct contact with the tRNA during translation
YP_422920.2	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_422945.1	related to short-chain alcohol dehydrogenase
YP_422947.1	catalyzes the formation of malonyl-CoA from malonate and CoA
YP_422974.1	class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine
YP_422978.1	catalytic chain
YP_422988.1	HD-GYP domain
YP_422993.1	putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_422998.2	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_423013.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_423014.1	Catalyzes the conversion of citrate to isocitrate
YP_423030.1	ISmag6,orf1; similar to IS3 family
YP_423031.1	ISmag6,orf2; similar to IS3 family
YP_423036.1	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_423039.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_423041.1	NACHT family
YP_423051.1	Site-specific recombinase XerD
YP_423058.1	MFS superfamily
YP_423070.1	large subunit CoxL/CutL homolog
YP_423081.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_423092.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_423111.1	TPR repeats
YP_423118.1	ISmag6,orf1; similar to IS3 family
YP_423119.1	ISmag6,orf2; similar to IS3 family
YP_423131.1	Site-specific recombinase XerD
YP_423154.1	SPINDLY family
YP_423155.1	SPINDLY family
YP_423163.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_423164.1	related to short-chain alcohol dehydrogenase
YP_423166.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_423169.1	CMP-KDO synthetase homolog
YP_423173.1	SPINDLY family
YP_423181.1	typically selenocysteine-containing
YP_423186.1	regulator of the sigma 54 transcriptional activator FlbD; represses FlbD when the class II flagellar structure is absent and activates FlbD when the structure is present
YP_423187.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
YP_423194.1	related to short-chain alcohol dehydrogenase
YP_423195.1	yjgF family
YP_423204.1	links inner and outer membranes
YP_423206.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_423208.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_423209.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_423211.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_423212.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_423214.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_423218.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_423221.1	BRCT domain type II
YP_423225.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_423236.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_423237.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_423249.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_423253.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_423258.1	HAD superfamily
YP_423263.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_423265.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_423276.1	activity unknown
YP_423288.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_423300.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_423301.1	Ntr-type
YP_423315.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_423316.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_423320.1	Catalyzes the reversible oxidation of malate to oxaloacetate
YP_423321.1	beta subunit
YP_423322.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_423324.2	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_423325.1	dihydrolipoamide acyltransferase (E2) component, and related enzyme
YP_423326.1	dihydrolipoamide dehydrogenase (E3) component, and related enzyme
YP_423335.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
YP_423337.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_423338.1	dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate
YP_423349.1	muraminidase
YP_423352.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_423356.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_423364.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
YP_423373.2	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_423382.1	TPR repeat
YP_423385.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_423387.1	ISmag4; similar to IS630 family
YP_423401.1	ISmag6,orf1; similar to IS3 family
YP_423402.1	ISmag6,orf2; similar to IS3 family
YP_423407.1	DNA invertase Pin homolog
YP_423423.1	family 3
YP_423426.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_423427.1	Essential for efficient processing of 16S rRNA
YP_423428.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_423429.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_423430.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_423431.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_423432.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_423433.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_423434.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_423436.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_423438.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_423441.1	involved in the peptidyltransferase reaction during translation
YP_423442.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_423443.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_423445.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_423447.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_423450.1	SpoU class
YP_423456.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_423466.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_423474.1	functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins
YP_423478.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_423479.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_423480.1	polynucleotide phosphorylase
YP_423482.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_423484.1	Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate
YP_423486.1	isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway
YP_423502.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_423503.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_423504.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_423505.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_423516.1	inhibitor of MCP methylation
YP_423525.1	helicase and exonuclease domains
YP_423530.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_423531.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_423537.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_423543.1	ATP-binding protein; required for proper cytochrome c maturation
YP_423547.1	ribokinase family
YP_423562.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
YP_423567.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_423586.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_423587.1	protein associated with Co2+ and Mg2+ efflux
YP_423589.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_423610.1	eIF-2Bgamma/eIF-2Bepsilon
YP_423613.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_423616.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_423624.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_423626.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_423655.1	Site-specific recombinase XerD
YP_423670.1	ISmag1,partial; similar to IS5 family
YP_423671.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
YP_423681.1	similar to M xanthus CarD
YP_423683.1	possibly involved in tellurium resistance
YP_423684.1	EAL and a GGDEF domain
YP_423698.1	catalyzes the ATP-dependent transport of cobalt
YP_423706.1	molecular chaperone
YP_423709.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_423710.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_423711.1	general stress protein Ctc
YP_423719.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_423720.2	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_423732.1	Anaerobic aromatic degradation regulator
YP_423733.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_423734.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_423743.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_423746.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_423754.1	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine
YP_423756.1	PTS system EI component in bacteria
YP_423763.2	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_423779.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_423781.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_423782.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_423789.1	G3E family
YP_423790.1	with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism
YP_423791.1	ISmag6,orf1; similar to IS3 family
YP_423792.1	ISmag6,orf2; similar to IS3 family
YP_423798.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_423800.1	flavoprotein
YP_423803.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_423804.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_423818.1	catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis
YP_423826.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_423832.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_423833.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_423839.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
YP_423849.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_423852.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_423857.1	EAL and a GGDEF domain
YP_423860.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_423861.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_423862.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_423863.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_423869.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_423877.1	DNA invertase Pin homolog
YP_423893.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_423894.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_423897.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_423899.1	heat shock protein involved in degradation of misfolded proteins
YP_423900.1	heat shock protein involved in degradation of misfolded proteins
YP_423903.1	conserved in bacteria
YP_423906.1	conserved in bacteria
YP_423907.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_423909.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_423910.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_423913.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_423914.1	ferrochelatase
YP_423916.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes