-- dump date   	20140619_135223
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1311760000001	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1311760000002	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1311760000003	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1311760000004	Putative helicase; Region: TraI_2; pfam07514
1311760000005	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1311760000006	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1311760000007	active site
1311760000008	catalytic residues [active]
1311760000009	DNA binding site [nucleotide binding]
1311760000010	Int/Topo IB signature motif; other site
1311760000011	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1311760000012	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760000013	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760000014	Integrase core domain; Region: rve; pfam00665
1311760000015	Integrase core domain; Region: rve_3; pfam13683
1311760000016	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1311760000017	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1311760000018	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1311760000019	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1311760000020	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1311760000021	dimer interface [polypeptide binding]; other site
1311760000022	ssDNA binding site [nucleotide binding]; other site
1311760000023	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1311760000024	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1311760000025	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1311760000026	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1311760000027	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1311760000028	putative transporter; Provisional; Region: PRK11660
1311760000029	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1311760000030	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1311760000031	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1311760000032	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760000033	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1311760000034	TM-ABC transporter signature motif; other site
1311760000035	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1311760000036	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760000037	Walker A/P-loop; other site
1311760000038	ATP binding site [chemical binding]; other site
1311760000039	Q-loop/lid; other site
1311760000040	ABC transporter signature motif; other site
1311760000041	Walker B; other site
1311760000042	D-loop; other site
1311760000043	H-loop/switch region; other site
1311760000044	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1311760000045	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1311760000046	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1311760000047	LrgA family; Region: LrgA; cl00608
1311760000048	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1311760000049	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1311760000050	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1311760000051	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1311760000052	Walker A/P-loop; other site
1311760000053	ATP binding site [chemical binding]; other site
1311760000054	Q-loop/lid; other site
1311760000055	ABC transporter signature motif; other site
1311760000056	Walker B; other site
1311760000057	D-loop; other site
1311760000058	H-loop/switch region; other site
1311760000059	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1311760000060	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1311760000061	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1311760000062	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1311760000063	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1311760000064	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1311760000065	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1311760000066	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760000067	active site
1311760000068	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1311760000069	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1311760000070	quinone interaction residues [chemical binding]; other site
1311760000071	active site
1311760000072	catalytic residues [active]
1311760000073	FMN binding site [chemical binding]; other site
1311760000074	substrate binding site [chemical binding]; other site
1311760000075	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1311760000076	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1311760000077	dimer interface [polypeptide binding]; other site
1311760000078	TPP-binding site [chemical binding]; other site
1311760000079	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1311760000080	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1311760000081	E3 interaction surface; other site
1311760000082	lipoyl attachment site [posttranslational modification]; other site
1311760000083	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1311760000084	E3 interaction surface; other site
1311760000085	lipoyl attachment site [posttranslational modification]; other site
1311760000086	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1311760000087	E3 interaction surface; other site
1311760000088	lipoyl attachment site [posttranslational modification]; other site
1311760000089	e3 binding domain; Region: E3_binding; pfam02817
1311760000090	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1311760000091	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1311760000092	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1311760000093	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1311760000094	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1311760000095	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
1311760000096	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1311760000097	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1311760000098	trimer interface [polypeptide binding]; other site
1311760000099	eyelet of channel; other site
1311760000100	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1311760000101	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1311760000102	Substrate binding site; other site
1311760000103	Mg++ binding site; other site
1311760000104	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1311760000105	active site
1311760000106	substrate binding site [chemical binding]; other site
1311760000107	CoA binding site [chemical binding]; other site
1311760000108	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760000109	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760000110	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1311760000111	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760000112	S-adenosylmethionine binding site [chemical binding]; other site
1311760000113	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1311760000114	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760000115	Walker A motif; other site
1311760000116	ATP binding site [chemical binding]; other site
1311760000117	Walker B motif; other site
1311760000118	arginine finger; other site
1311760000119	Peptidase family M41; Region: Peptidase_M41; pfam01434
1311760000120	xanthine permease; Region: pbuX; TIGR03173
1311760000121	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
1311760000122	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1311760000123	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760000124	homodimer interface [polypeptide binding]; other site
1311760000125	catalytic residue [active]
1311760000126	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1311760000127	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1311760000128	hinge; other site
1311760000129	active site
1311760000130	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
1311760000131	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1311760000132	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1311760000133	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1311760000134	Protein of unknown function DUF47; Region: PhoU_div; pfam01865
1311760000135	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1311760000136	homodimer interface [polypeptide binding]; other site
1311760000137	substrate-cofactor binding pocket; other site
1311760000138	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760000139	catalytic residue [active]
1311760000140	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1311760000141	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1311760000142	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1311760000143	PII uridylyl-transferase; Provisional; Region: glnD; PRK01759
1311760000144	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1311760000145	metal binding triad; other site
1311760000146	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1311760000147	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1311760000148	Zn2+ binding site [ion binding]; other site
1311760000149	Mg2+ binding site [ion binding]; other site
1311760000150	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1311760000151	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1311760000152	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1311760000153	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1311760000154	Walker A/P-loop; other site
1311760000155	ATP binding site [chemical binding]; other site
1311760000156	Q-loop/lid; other site
1311760000157	ABC transporter signature motif; other site
1311760000158	Walker B; other site
1311760000159	D-loop; other site
1311760000160	H-loop/switch region; other site
1311760000161	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1311760000162	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760000163	ABC-ATPase subunit  interface; other site
1311760000164	dimer interface [polypeptide binding]; other site
1311760000165	putative PBP binding regions; other site
1311760000166	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1311760000167	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1311760000168	putative ligand binding residues [chemical binding]; other site
1311760000169	replicative DNA helicase; Validated; Region: PRK06904
1311760000170	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1311760000171	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1311760000172	Walker A motif; other site
1311760000173	ATP binding site [chemical binding]; other site
1311760000174	Walker B motif; other site
1311760000175	DNA binding loops [nucleotide binding]
1311760000176	YcgL domain; Region: YcgL; pfam05166
1311760000177	transcriptional regulator NrdR; Region: TIGR00244
1311760000178	ATP cone domain; Region: ATP-cone; pfam03477
1311760000179	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1311760000180	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1311760000181	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760000182	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1311760000183	dimerization interface [polypeptide binding]; other site
1311760000184	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1311760000185	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1311760000186	FMN binding site [chemical binding]; other site
1311760000187	substrate binding site [chemical binding]; other site
1311760000188	putative catalytic residue [active]
1311760000189	hypothetical protein; Provisional; Region: PRK11018
1311760000190	CPxP  motif; other site
1311760000191	putative inner membrane protein; Provisional; Region: PRK11099
1311760000192	putative inner membrane protein; Provisional; Region: PRK11099
1311760000193	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
1311760000194	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1311760000195	putative N- and C-terminal domain interface [polypeptide binding]; other site
1311760000196	putative active site [active]
1311760000197	MgATP binding site [chemical binding]; other site
1311760000198	catalytic site [active]
1311760000199	metal binding site [ion binding]; metal-binding site
1311760000200	putative carbohydrate binding site [chemical binding]; other site
1311760000201	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760000202	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760000203	TM-ABC transporter signature motif; other site
1311760000204	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760000205	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760000206	TM-ABC transporter signature motif; other site
1311760000207	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1311760000208	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760000209	Walker A/P-loop; other site
1311760000210	ATP binding site [chemical binding]; other site
1311760000211	Q-loop/lid; other site
1311760000212	ABC transporter signature motif; other site
1311760000213	Walker B; other site
1311760000214	D-loop; other site
1311760000215	H-loop/switch region; other site
1311760000216	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760000217	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1311760000218	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1311760000219	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1311760000220	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1311760000221	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760000222	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760000223	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1311760000224	DNA-binding site [nucleotide binding]; DNA binding site
1311760000225	RNA-binding motif; other site
1311760000226	Protein of unknown function (DUF1439); Region: DUF1439; pfam07273
1311760000227	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1311760000228	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1311760000229	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1311760000230	CPxP  motif; other site
1311760000231	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760000232	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760000233	Catalytic site [active]
1311760000234	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1311760000235	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760000236	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760000237	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1311760000238	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1311760000239	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1311760000240	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1311760000241	N-terminal plug; other site
1311760000242	ligand-binding site [chemical binding]; other site
1311760000243	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1311760000244	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760000245	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
1311760000246	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1311760000247	Flavoprotein; Region: Flavoprotein; pfam02441
1311760000248	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1311760000249	Invasion gene expression up-regulator, SirB; Region: SirB; pfam04247
1311760000250	hypothetical protein; Provisional; Region: PRK05255
1311760000251	peptidase PmbA; Provisional; Region: PRK11040
1311760000252	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760000253	active site
1311760000254	Neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: NanH; COG4409
1311760000255	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
1311760000256	catalytic site [active]
1311760000257	Asp-box motif; other site
1311760000258	Autotransporter beta-domain; Region: Autotransporter; cl17461
1311760000259	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
1311760000260	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1311760000261	probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684
1311760000262	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1311760000263	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1311760000264	active site
1311760000265	Int/Topo IB signature motif; other site
1311760000266	silicon transporter; Region: sit; TIGR00811
1311760000267	Ash protein family; Region: Phage_ASH; pfam10554
1311760000268	Ash protein family; Region: Phage_ASH; pfam10554
1311760000269	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1311760000270	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
1311760000271	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1311760000272	integrase; Provisional; Region: PRK09692
1311760000273	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1311760000274	active site
1311760000275	Int/Topo IB signature motif; other site
1311760000276	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1311760000277	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
1311760000278	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1311760000279	homotrimer interaction site [polypeptide binding]; other site
1311760000280	putative active site [active]
1311760000281	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1311760000282	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1311760000283	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
1311760000284	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1311760000285	glutamate dehydrogenase; Provisional; Region: PRK09414
1311760000286	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1311760000287	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1311760000288	NAD(P) binding site [chemical binding]; other site
1311760000289	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1311760000290	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760000291	DNA binding site [nucleotide binding]
1311760000292	domain linker motif; other site
1311760000293	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1311760000294	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1311760000295	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1311760000296	active site
1311760000297	HIGH motif; other site
1311760000298	nucleotide binding site [chemical binding]; other site
1311760000299	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1311760000300	KMSKS motif; other site
1311760000301	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1311760000302	SnoaL-like domain; Region: SnoaL_4; pfam13577
1311760000303	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760000304	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1311760000305	NAD(P) binding site [chemical binding]; other site
1311760000306	active site
1311760000307	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1311760000308	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760000309	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1311760000310	putative effector binding pocket; other site
1311760000311	putative dimerization interface [polypeptide binding]; other site
1311760000312	elongation factor P; Validated; Region: PRK00529
1311760000313	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1311760000314	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1311760000315	RNA binding site [nucleotide binding]; other site
1311760000316	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1311760000317	RNA binding site [nucleotide binding]; other site
1311760000318	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760000319	FeS/SAM binding site; other site
1311760000320	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1311760000321	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1311760000322	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1311760000323	putative dimer interface [polypeptide binding]; other site
1311760000324	putative anticodon binding site; other site
1311760000325	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1311760000326	homodimer interface [polypeptide binding]; other site
1311760000327	motif 1; other site
1311760000328	motif 2; other site
1311760000329	active site
1311760000330	motif 3; other site
1311760000331	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1311760000332	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760000333	active site
1311760000334	DNA binding site [nucleotide binding]
1311760000335	Int/Topo IB signature motif; other site
1311760000336	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1311760000337	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u3; cd11540
1311760000338	putative metal binding site [ion binding]; other site
1311760000339	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1311760000340	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1311760000341	RecT family; Region: RecT; pfam03837
1311760000342	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1311760000343	metal binding site [ion binding]; metal-binding site
1311760000344	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1311760000345	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760000346	sequence-specific DNA binding site [nucleotide binding]; other site
1311760000347	salt bridge; other site
1311760000348	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760000349	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760000350	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760000351	Integrase core domain; Region: rve; pfam00665
1311760000352	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760000353	Integrase core domain; Region: rve_3; pfam13683
1311760000354	Haemolysin XhlA; Region: XhlA; pfam10779
1311760000355	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760000356	non-specific DNA binding site [nucleotide binding]; other site
1311760000357	salt bridge; other site
1311760000358	sequence-specific DNA binding site [nucleotide binding]; other site
1311760000359	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760000360	Catalytic site [active]
1311760000361	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760000362	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1311760000363	non-specific DNA binding site [nucleotide binding]; other site
1311760000364	salt bridge; other site
1311760000365	sequence-specific DNA binding site [nucleotide binding]; other site
1311760000366	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
1311760000367	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1311760000368	replicative DNA helicase; Region: DnaB; TIGR00665
1311760000369	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1311760000370	Walker A motif; other site
1311760000371	ATP binding site [chemical binding]; other site
1311760000372	Walker B motif; other site
1311760000373	MT-A70; Region: MT-A70; cl01947
1311760000374	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1311760000375	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1311760000376	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1311760000377	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1311760000378	catalytic residues [active]
1311760000379	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1311760000380	Terminase small subunit; Region: Terminase_2; pfam03592
1311760000381	Phage terminase large subunit; Region: Terminase_3; cl12054
1311760000382	Terminase-like family; Region: Terminase_6; pfam03237
1311760000383	Domain of unknown function (DUF4055); Region: DUF4055; pfam13264
1311760000384	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1311760000385	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1311760000386	metal binding triad [ion binding]; metal-binding site
1311760000387	HD domain; Region: HD_4; pfam13328
1311760000388	Bacteriophage related domain of unknown function; Region: DUF4128; pfam13554
1311760000389	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1311760000390	tape measure domain; Region: tape_meas_nterm; TIGR02675
1311760000391	Phage-related protein [Function unknown]; Region: gp18; COG4672
1311760000392	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1311760000393	MPN+ (JAMM) motif; other site
1311760000394	Zinc-binding site [ion binding]; other site
1311760000395	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1311760000396	NlpC/P60 family; Region: NLPC_P60; cl17555
1311760000397	Phage-related protein, tail component [Function unknown]; Region: COG4723
1311760000398	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1311760000399	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1311760000400	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1311760000401	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1311760000402	CoA binding domain; Region: CoA_binding; pfam02629
1311760000403	CoA-ligase; Region: Ligase_CoA; pfam00549
1311760000404	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1311760000405	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1311760000406	CoA-ligase; Region: Ligase_CoA; pfam00549
1311760000407	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1311760000408	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1311760000409	E3 interaction surface; other site
1311760000410	lipoyl attachment site [posttranslational modification]; other site
1311760000411	e3 binding domain; Region: E3_binding; pfam02817
1311760000412	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1311760000413	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1311760000414	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1311760000415	TPP-binding site [chemical binding]; other site
1311760000416	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1311760000417	dimer interface [polypeptide binding]; other site
1311760000418	PYR/PP interface [polypeptide binding]; other site
1311760000419	TPP binding site [chemical binding]; other site
1311760000420	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1311760000421	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1311760000422	putative peptidase; Provisional; Region: PRK11649
1311760000423	Peptidase family M23; Region: Peptidase_M23; pfam01551
1311760000424	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1311760000425	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1311760000426	dimerization domain [polypeptide binding]; other site
1311760000427	dimer interface [polypeptide binding]; other site
1311760000428	catalytic residues [active]
1311760000429	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1311760000430	DHH family; Region: DHH; pfam01368
1311760000431	DHHA1 domain; Region: DHHA1; pfam02272
1311760000432	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
1311760000433	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1311760000434	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1311760000435	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1311760000436	ligand binding site [chemical binding]; other site
1311760000437	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1311760000438	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760000439	active site
1311760000440	motif I; other site
1311760000441	motif II; other site
1311760000442	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760000443	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760000444	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1311760000445	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1311760000446	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1311760000447	dimerization interface [polypeptide binding]; other site
1311760000448	Histidine kinase; Region: HisKA_3; pfam07730
1311760000449	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760000450	ATP binding site [chemical binding]; other site
1311760000451	Mg2+ binding site [ion binding]; other site
1311760000452	G-X-G motif; other site
1311760000453	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1311760000454	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760000455	Coenzyme A binding pocket [chemical binding]; other site
1311760000456	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1311760000457	active site
1311760000458	dimerization interface [polypeptide binding]; other site
1311760000459	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1311760000460	hypothetical protein; Provisional; Region: PRK05170
1311760000461	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1311760000462	dimer interface [polypeptide binding]; other site
1311760000463	active site
1311760000464	Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism]; Region: TyrR; COG3283
1311760000465	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760000466	Walker A motif; other site
1311760000467	ATP binding site [chemical binding]; other site
1311760000468	Walker B motif; other site
1311760000469	arginine finger; other site
1311760000470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760000471	dimer interface [polypeptide binding]; other site
1311760000472	conserved gate region; other site
1311760000473	putative PBP binding loops; other site
1311760000474	ABC-ATPase subunit interface; other site
1311760000475	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapC; COG4171
1311760000476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760000477	dimer interface [polypeptide binding]; other site
1311760000478	conserved gate region; other site
1311760000479	putative PBP binding loops; other site
1311760000480	ABC-ATPase subunit interface; other site
1311760000481	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SapD; COG4170
1311760000482	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760000483	Walker A/P-loop; other site
1311760000484	ATP binding site [chemical binding]; other site
1311760000485	Q-loop/lid; other site
1311760000486	ABC transporter signature motif; other site
1311760000487	Walker B; other site
1311760000488	D-loop; other site
1311760000489	H-loop/switch region; other site
1311760000490	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1311760000491	Protein of unknown function (DUF1375); Region: DUF1375; pfam07119
1311760000492	tartrate dehydrogenase; Region: TTC; TIGR02089
1311760000493	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1311760000494	SelR domain; Region: SelR; pfam01641
1311760000495	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1311760000496	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1311760000497	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1311760000498	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1311760000499	portal vertex protein; Provisional; Region: Q; PHA02536
1311760000500	Phage portal protein; Region: Phage_portal; pfam04860
1311760000501	terminase ATPase subunit; Provisional; Region: P; PHA02535
1311760000502	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1311760000503	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1311760000504	capsid-scaffolding protein; Provisional; Region: O; PHA02529
1311760000505	capsid protein; Provisional; Region: N; PHA02538
1311760000506	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1311760000507	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1311760000508	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1311760000509	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1311760000510	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1311760000511	catalytic residues [active]
1311760000512	phage lambda Rz1-like protein; Region: PHA02047
1311760000513	DksA-like zinc finger domain containing protein; Region: PHA00080
1311760000514	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1311760000515	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1311760000516	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1311760000517	Mu-like prophage protein [General function prediction only]; Region: COG3941
1311760000518	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
1311760000519	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1311760000520	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1311760000521	baseplate wedge subunit; Provisional; Region: W; PHA02516
1311760000522	baseplate assembly protein; Provisional; Region: J; PHA02568
1311760000523	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
1311760000524	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1311760000525	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1311760000526	major tail sheath protein; Provisional; Region: FI; PHA02560
1311760000527	major tail tube protein; Provisional; Region: FII; PHA02600
1311760000528	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1311760000529	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1311760000530	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1311760000531	tail protein; Provisional; Region: D; PHA02561
1311760000532	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1311760000533	Excalibur calcium-binding domain; Region: Excalibur; pfam05901
1311760000534	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1311760000535	Dimer interface [polypeptide binding]; other site
1311760000536	BRCT sequence motif; other site
1311760000537	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1311760000538	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760000539	non-specific DNA binding site [nucleotide binding]; other site
1311760000540	salt bridge; other site
1311760000541	sequence-specific DNA binding site [nucleotide binding]; other site
1311760000542	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760000543	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760000544	Catalytic site [active]
1311760000545	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760000546	non-specific DNA binding site [nucleotide binding]; other site
1311760000547	salt bridge; other site
1311760000548	sequence-specific DNA binding site [nucleotide binding]; other site
1311760000549	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1311760000550	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1311760000551	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1311760000552	dimer interface [polypeptide binding]; other site
1311760000553	ssDNA binding site [nucleotide binding]; other site
1311760000554	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1311760000555	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1311760000556	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760000557	active site
1311760000558	DNA binding site [nucleotide binding]
1311760000559	Int/Topo IB signature motif; other site
1311760000560	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1311760000561	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1311760000562	active site
1311760000563	metal binding site [ion binding]; metal-binding site
1311760000564	exoribonuclease II; Provisional; Region: PRK05054
1311760000565	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1311760000566	RNB domain; Region: RNB; pfam00773
1311760000567	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1311760000568	RNA binding site [nucleotide binding]; other site
1311760000569	Bor protein; Region: Lambda_Bor; pfam06291
1311760000570	Bor protein; Region: Lambda_Bor; pfam06291
1311760000571	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
1311760000572	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1311760000573	NAD binding site [chemical binding]; other site
1311760000574	homotetramer interface [polypeptide binding]; other site
1311760000575	homodimer interface [polypeptide binding]; other site
1311760000576	substrate binding site [chemical binding]; other site
1311760000577	active site
1311760000578	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1311760000579	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1311760000580	ligand binding site [chemical binding]; other site
1311760000581	flexible hinge region; other site
1311760000582	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1311760000583	putative switch regulator; other site
1311760000584	non-specific DNA interactions [nucleotide binding]; other site
1311760000585	DNA binding site [nucleotide binding]
1311760000586	sequence specific DNA binding site [nucleotide binding]; other site
1311760000587	putative cAMP binding site [chemical binding]; other site
1311760000588	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1311760000589	Ligand Binding Site [chemical binding]; other site
1311760000590	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1311760000591	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1311760000592	motif 1; other site
1311760000593	active site
1311760000594	motif 2; other site
1311760000595	motif 3; other site
1311760000596	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1311760000597	DHHA1 domain; Region: DHHA1; pfam02272
1311760000598	carbon storage regulator; Provisional; Region: PRK01712
1311760000599	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1311760000600	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1311760000601	active site
1311760000602	tetramer interface; other site
1311760000603	condesin subunit F; Provisional; Region: PRK05260
1311760000604	condesin subunit E; Provisional; Region: PRK05256
1311760000605	cell division protein MukB; Provisional; Region: mukB; PRK04863
1311760000606	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1311760000607	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1311760000608	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1311760000609	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1311760000610	Sulfatase; Region: Sulfatase; cl17466
1311760000611	hypothetical protein; Provisional; Region: PRK13689
1311760000612	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1311760000613	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1311760000614	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1311760000615	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1311760000616	HlyD family secretion protein; Region: HlyD_3; pfam13437
1311760000617	multidrug efflux protein; Reviewed; Region: PRK09579
1311760000618	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1311760000619	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1311760000620	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1311760000621	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1311760000622	active site
1311760000623	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1311760000624	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760000625	motif II; other site
1311760000626	GMP synthase; Reviewed; Region: guaA; PRK00074
1311760000627	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1311760000628	AMP/PPi binding site [chemical binding]; other site
1311760000629	candidate oxyanion hole; other site
1311760000630	catalytic triad [active]
1311760000631	potential glutamine specificity residues [chemical binding]; other site
1311760000632	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1311760000633	ATP Binding subdomain [chemical binding]; other site
1311760000634	Ligand Binding sites [chemical binding]; other site
1311760000635	Dimerization subdomain; other site
1311760000636	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1311760000637	Protein of unknown function (DUF1043); Region: DUF1043; pfam06295
1311760000638	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1311760000639	23S rRNA interface [nucleotide binding]; other site
1311760000640	L3 interface [polypeptide binding]; other site
1311760000641	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1311760000642	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
1311760000643	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1311760000644	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1311760000645	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1311760000646	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1311760000647	putative active site [active]
1311760000648	putative nucleic acid binding site [nucleotide binding]; other site
1311760000649	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
1311760000650	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1311760000651	active site
1311760000652	hypothetical protein; Validated; Region: PRK02101
1311760000653	Cation efflux family; Region: Cation_efflux; cl00316
1311760000654	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1311760000655	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310); Region: DUF2310; pfam10071
1311760000656	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1311760000657	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1311760000658	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1311760000659	dimer interface [polypeptide binding]; other site
1311760000660	FMN binding site [chemical binding]; other site
1311760000661	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1311760000662	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1311760000663	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1311760000664	dimer interface [polypeptide binding]; other site
1311760000665	motif 1; other site
1311760000666	active site
1311760000667	motif 2; other site
1311760000668	motif 3; other site
1311760000669	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1311760000670	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1311760000671	putative tRNA-binding site [nucleotide binding]; other site
1311760000672	B3/4 domain; Region: B3_4; pfam03483
1311760000673	tRNA synthetase B5 domain; Region: B5; smart00874
1311760000674	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1311760000675	dimer interface [polypeptide binding]; other site
1311760000676	motif 1; other site
1311760000677	motif 3; other site
1311760000678	motif 2; other site
1311760000679	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
1311760000680	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1311760000681	IHF dimer interface [polypeptide binding]; other site
1311760000682	IHF - DNA interface [nucleotide binding]; other site
1311760000683	NlpC/P60 family; Region: NLPC_P60; pfam00877
1311760000684	serine endoprotease; Provisional; Region: PRK10898
1311760000685	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1311760000686	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1311760000687	protein binding site [polypeptide binding]; other site
1311760000688	cytidylate kinase; Provisional; Region: cmk; PRK00023
1311760000689	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1311760000690	CMP-binding site; other site
1311760000691	The sites determining sugar specificity; other site
1311760000692	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1311760000693	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1311760000694	RNA binding site [nucleotide binding]; other site
1311760000695	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1311760000696	RNA binding site [nucleotide binding]; other site
1311760000697	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1311760000698	RNA binding site [nucleotide binding]; other site
1311760000699	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1311760000700	RNA binding site [nucleotide binding]; other site
1311760000701	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1311760000702	RNA binding site [nucleotide binding]; other site
1311760000703	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1311760000704	RNA binding site [nucleotide binding]; other site
1311760000705	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1311760000706	IHF dimer interface [polypeptide binding]; other site
1311760000707	IHF - DNA interface [nucleotide binding]; other site
1311760000708	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
1311760000709	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1311760000710	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1311760000711	binding surface
1311760000712	TPR motif; other site
1311760000713	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760000714	TPR motif; other site
1311760000715	binding surface
1311760000716	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1311760000717	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1311760000718	active site
1311760000719	dimer interface [polypeptide binding]; other site
1311760000720	translation initiation factor Sui1; Validated; Region: PRK06824
1311760000721	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1311760000722	putative rRNA binding site [nucleotide binding]; other site
1311760000723	lytic murein transglycosylase; Provisional; Region: PRK11619
1311760000724	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1311760000725	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1311760000726	catalytic residue [active]
1311760000727	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1311760000728	Sm and related proteins; Region: Sm_like; cl00259
1311760000729	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1311760000730	putative oligomer interface [polypeptide binding]; other site
1311760000731	putative RNA binding site [nucleotide binding]; other site
1311760000732	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1311760000733	NusA N-terminal domain; Region: NusA_N; pfam08529
1311760000734	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1311760000735	RNA binding site [nucleotide binding]; other site
1311760000736	homodimer interface [polypeptide binding]; other site
1311760000737	NusA-like KH domain; Region: KH_5; pfam13184
1311760000738	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1311760000739	G-X-X-G motif; other site
1311760000740	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1311760000741	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1311760000742	translation initiation factor IF-2; Region: IF-2; TIGR00487
1311760000743	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1311760000744	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1311760000745	G1 box; other site
1311760000746	putative GEF interaction site [polypeptide binding]; other site
1311760000747	GTP/Mg2+ binding site [chemical binding]; other site
1311760000748	Switch I region; other site
1311760000749	G2 box; other site
1311760000750	G3 box; other site
1311760000751	Switch II region; other site
1311760000752	G4 box; other site
1311760000753	G5 box; other site
1311760000754	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1311760000755	Translation-initiation factor 2; Region: IF-2; pfam11987
1311760000756	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1311760000757	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1311760000758	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1311760000759	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1311760000760	RNA binding site [nucleotide binding]; other site
1311760000761	active site
1311760000762	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1311760000763	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1311760000764	nucleoside/Zn binding site; other site
1311760000765	dimer interface [polypeptide binding]; other site
1311760000766	catalytic motif [active]
1311760000767	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
1311760000768	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1311760000769	ATP binding site [chemical binding]; other site
1311760000770	Mg++ binding site [ion binding]; other site
1311760000771	motif III; other site
1311760000772	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760000773	nucleotide binding region [chemical binding]; other site
1311760000774	ATP-binding site [chemical binding]; other site
1311760000775	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1311760000776	putative RNA binding site [nucleotide binding]; other site
1311760000777	lipoprotein NlpI; Provisional; Region: PRK11189
1311760000778	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760000779	binding surface
1311760000780	TPR motif; other site
1311760000781	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1311760000782	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1311760000783	RNase E interface [polypeptide binding]; other site
1311760000784	trimer interface [polypeptide binding]; other site
1311760000785	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1311760000786	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1311760000787	RNase E interface [polypeptide binding]; other site
1311760000788	trimer interface [polypeptide binding]; other site
1311760000789	active site
1311760000790	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1311760000791	putative nucleic acid binding region [nucleotide binding]; other site
1311760000792	G-X-X-G motif; other site
1311760000793	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1311760000794	RNA binding site [nucleotide binding]; other site
1311760000795	domain interface; other site
1311760000796	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1311760000797	PAS domain; Region: PAS; smart00091
1311760000798	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1311760000799	dimer interface [polypeptide binding]; other site
1311760000800	phosphorylation site [posttranslational modification]
1311760000801	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760000802	ATP binding site [chemical binding]; other site
1311760000803	Mg2+ binding site [ion binding]; other site
1311760000804	G-X-G motif; other site
1311760000805	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
1311760000806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1311760000807	active site
1311760000808	phosphorylation site [posttranslational modification]
1311760000809	intermolecular recognition site; other site
1311760000810	dimerization interface [polypeptide binding]; other site
1311760000811	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1311760000812	DNA binding site [nucleotide binding]
1311760000813	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1311760000814	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1311760000815	Walker A/P-loop; other site
1311760000816	ATP binding site [chemical binding]; other site
1311760000817	Q-loop/lid; other site
1311760000818	ABC transporter signature motif; other site
1311760000819	Walker B; other site
1311760000820	D-loop; other site
1311760000821	H-loop/switch region; other site
1311760000822	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1311760000823	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760000824	dimer interface [polypeptide binding]; other site
1311760000825	conserved gate region; other site
1311760000826	putative PBP binding loops; other site
1311760000827	ABC-ATPase subunit interface; other site
1311760000828	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760000829	dimer interface [polypeptide binding]; other site
1311760000830	conserved gate region; other site
1311760000831	putative PBP binding loops; other site
1311760000832	ABC-ATPase subunit interface; other site
1311760000833	PBP superfamily domain; Region: PBP_like_2; cl17296
1311760000834	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1311760000835	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1311760000836	CAP-like domain; other site
1311760000837	active site
1311760000838	primary dimer interface [polypeptide binding]; other site
1311760000839	aspartate kinase III; Validated; Region: PRK09084
1311760000840	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1311760000841	nucleotide binding site [chemical binding]; other site
1311760000842	substrate binding site [chemical binding]; other site
1311760000843	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1311760000844	lysine allosteric regulatory site; other site
1311760000845	dimer interface [polypeptide binding]; other site
1311760000846	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1311760000847	dimer interface [polypeptide binding]; other site
1311760000848	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1311760000849	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1311760000850	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1311760000851	active site turn [active]
1311760000852	phosphorylation site [posttranslational modification]
1311760000853	hypothetical protein; Provisional; Region: PRK05423
1311760000854	exopolyphosphatase; Provisional; Region: PRK10854
1311760000855	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1311760000856	Domain of unknown function (DUF386); Region: DUF386; cl01047
1311760000857	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1311760000858	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1311760000859	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1311760000860	putative active site [active]
1311760000861	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1311760000862	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1311760000863	active site
1311760000864	metal binding site [ion binding]; metal-binding site
1311760000865	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1311760000866	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1311760000867	serine/threonine transporter SstT; Provisional; Region: PRK13628
1311760000868	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1311760000869	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1311760000870	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
1311760000871	Competence protein; Region: Competence; pfam03772
1311760000872	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1311760000873	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1311760000874	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1311760000875	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1311760000876	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1311760000877	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1311760000878	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1311760000879	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1311760000880	adhesin HecA family 20-residue repeat (two copies); Region: fil_hemag_20aa; TIGR01731
1311760000881	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
1311760000882	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1311760000883	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
1311760000884	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
1311760000885	protein-splicing catalytic site; other site
1311760000886	thioester formation/cholesterol transfer; other site
1311760000887	Pretoxin HINT domain; Region: PT-HINT; pfam07591
1311760000888	HNH/ENDO VII superfamily nuclease with conserved GHE residues; Region: GH-E; pfam14410
1311760000889	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1311760000890	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1311760000891	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1311760000892	TPR repeat; Region: TPR_11; pfam13414
1311760000893	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760000894	binding surface
1311760000895	TPR motif; other site
1311760000896	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1311760000897	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1311760000898	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1311760000899	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1311760000900	ATP cone domain; Region: ATP-cone; pfam03477
1311760000901	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1311760000902	active site
1311760000903	dimer interface [polypeptide binding]; other site
1311760000904	catalytic residues [active]
1311760000905	effector binding site; other site
1311760000906	R2 peptide binding site; other site
1311760000907	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1311760000908	dimer interface [polypeptide binding]; other site
1311760000909	putative radical transfer pathway; other site
1311760000910	diiron center [ion binding]; other site
1311760000911	tyrosyl radical; other site
1311760000912	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1311760000913	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1311760000914	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1311760000915	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1311760000916	Walker A/P-loop; other site
1311760000917	ATP binding site [chemical binding]; other site
1311760000918	Q-loop/lid; other site
1311760000919	ABC transporter signature motif; other site
1311760000920	Walker B; other site
1311760000921	D-loop; other site
1311760000922	H-loop/switch region; other site
1311760000923	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1311760000924	FtsX-like permease family; Region: FtsX; pfam02687
1311760000925	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1311760000926	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1311760000927	dimerization interface [polypeptide binding]; other site
1311760000928	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1311760000929	dimer interface [polypeptide binding]; other site
1311760000930	phosphorylation site [posttranslational modification]
1311760000931	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760000932	ATP binding site [chemical binding]; other site
1311760000933	Mg2+ binding site [ion binding]; other site
1311760000934	G-X-G motif; other site
1311760000935	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1311760000936	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1311760000937	active site
1311760000938	phosphorylation site [posttranslational modification]
1311760000939	intermolecular recognition site; other site
1311760000940	dimerization interface [polypeptide binding]; other site
1311760000941	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1311760000942	DNA binding site [nucleotide binding]
1311760000943	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1311760000944	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1311760000945	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1311760000946	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760000947	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1311760000948	G4 box; other site
1311760000949	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1311760000950	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1311760000951	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760000952	homodimer interface [polypeptide binding]; other site
1311760000953	catalytic residue [active]
1311760000954	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1311760000955	Helicase; Region: Helicase_RecD; pfam05127
1311760000956	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760000957	Coenzyme A binding pocket [chemical binding]; other site
1311760000958	metal-binding heat shock protein; Provisional; Region: PRK00016
1311760000959	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1311760000960	MoaE homodimer interface [polypeptide binding]; other site
1311760000961	MoaD interaction [polypeptide binding]; other site
1311760000962	active site residues [active]
1311760000963	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1311760000964	MoaE interaction surface [polypeptide binding]; other site
1311760000965	MoeB interaction surface [polypeptide binding]; other site
1311760000966	thiocarboxylated glycine; other site
1311760000967	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1311760000968	trimer interface [polypeptide binding]; other site
1311760000969	dimer interface [polypeptide binding]; other site
1311760000970	putative active site [active]
1311760000971	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1311760000972	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760000973	FeS/SAM binding site; other site
1311760000974	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1311760000975	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1311760000976	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1311760000977	DNA binding residues [nucleotide binding]
1311760000978	dimerization interface [polypeptide binding]; other site
1311760000979	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1311760000980	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
1311760000981	ligand binding site [chemical binding]; other site
1311760000982	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
1311760000983	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1311760000984	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1311760000985	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1311760000986	molybdopterin cofactor binding site [chemical binding]; other site
1311760000987	substrate binding site [chemical binding]; other site
1311760000988	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1311760000989	molybdopterin cofactor binding site; other site
1311760000990	ARP2/3 complex 16 kDa subunit (p16-Arc); Region: P16-Arc; pfam04699
1311760000991	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1311760000992	DNA methylase; Region: N6_N4_Mtase; pfam01555
1311760000993	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1311760000994	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1311760000995	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1311760000996	dimer interface [polypeptide binding]; other site
1311760000997	active site
1311760000998	citrylCoA binding site [chemical binding]; other site
1311760000999	NADH binding [chemical binding]; other site
1311760001000	cationic pore residues; other site
1311760001001	oxalacetate/citrate binding site [chemical binding]; other site
1311760001002	coenzyme A binding site [chemical binding]; other site
1311760001003	catalytic triad [active]
1311760001004	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1311760001005	isocitrate dehydrogenase; Validated; Region: PRK07362
1311760001006	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1311760001007	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1311760001008	substrate binding site [chemical binding]; other site
1311760001009	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1311760001010	substrate binding site [chemical binding]; other site
1311760001011	ligand binding site [chemical binding]; other site
1311760001012	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1311760001013	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1311760001014	molybdopterin cofactor binding site [chemical binding]; other site
1311760001015	substrate binding site [chemical binding]; other site
1311760001016	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1311760001017	molybdopterin cofactor binding site; other site
1311760001018	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1311760001019	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1311760001020	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1311760001021	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1311760001022	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1311760001023	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1311760001024	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1311760001025	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1311760001026	cystathionine gamma-synthase; Reviewed; Region: PRK08247
1311760001027	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1311760001028	homodimer interface [polypeptide binding]; other site
1311760001029	substrate-cofactor binding pocket; other site
1311760001030	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760001031	catalytic residue [active]
1311760001032	chloroplast protein import component Toc86/159, G and M domains; Region: 3a0901s04IAP86; TIGR00993
1311760001033	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1311760001034	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
1311760001035	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1311760001036	Protein of unknown function (DUF1778); Region: DUF1778; cl01845
1311760001037	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
1311760001038	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
1311760001039	active site
1311760001040	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1311760001041	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1311760001042	active site
1311760001043	metal binding site [ion binding]; metal-binding site
1311760001044	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1311760001045	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1311760001046	propionate/acetate kinase; Provisional; Region: PRK12379
1311760001047	phosphate acetyltransferase; Reviewed; Region: PRK05632
1311760001048	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1311760001049	DRTGG domain; Region: DRTGG; pfam07085
1311760001050	phosphate acetyltransferase; Region: pta; TIGR00651
1311760001051	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1311760001052	active site clefts [active]
1311760001053	zinc binding site [ion binding]; other site
1311760001054	dimer interface [polypeptide binding]; other site
1311760001055	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06882
1311760001056	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1311760001057	PYR/PP interface [polypeptide binding]; other site
1311760001058	dimer interface [polypeptide binding]; other site
1311760001059	TPP binding site [chemical binding]; other site
1311760001060	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1311760001061	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1311760001062	TPP-binding site [chemical binding]; other site
1311760001063	dimer interface [polypeptide binding]; other site
1311760001064	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1311760001065	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1311760001066	putative valine binding site [chemical binding]; other site
1311760001067	dimer interface [polypeptide binding]; other site
1311760001068	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1311760001069	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1311760001070	EamA-like transporter family; Region: EamA; pfam00892
1311760001071	EamA-like transporter family; Region: EamA; pfam00892
1311760001072	N-acetylglutamate synthase; Validated; Region: PRK05279
1311760001073	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1311760001074	putative feedback inhibition sensing region; other site
1311760001075	putative nucleotide binding site [chemical binding]; other site
1311760001076	putative substrate binding site [chemical binding]; other site
1311760001077	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760001078	Coenzyme A binding pocket [chemical binding]; other site
1311760001079	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1311760001080	proline aminopeptidase P II; Provisional; Region: PRK10879
1311760001081	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1311760001082	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1311760001083	active site
1311760001084	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1311760001085	Protein of unknown function (DUF904); Region: DUF904; pfam06005
1311760001086	thymidine kinase; Provisional; Region: PRK04296
1311760001087	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1311760001088	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1311760001089	Sulfatase; Region: Sulfatase; cl17466
1311760001090	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1311760001091	putative transporter; Provisional; Region: PRK10484
1311760001092	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
1311760001093	Na binding site [ion binding]; other site
1311760001094	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1311760001095	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1311760001096	ligand binding site [chemical binding]; other site
1311760001097	flexible hinge region; other site
1311760001098	Predicted permeases [General function prediction only]; Region: COG0730
1311760001099	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1311760001100	Glycoprotease family; Region: Peptidase_M22; pfam00814
1311760001101	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1311760001102	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1311760001103	Predicted metalloprotease [General function prediction only]; Region: COG2321
1311760001104	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1311760001105	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1311760001106	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1311760001107	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1311760001108	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1311760001109	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1311760001110	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1311760001111	dimerization interface [polypeptide binding]; other site
1311760001112	putative DNA binding site [nucleotide binding]; other site
1311760001113	putative Zn2+ binding site [ion binding]; other site
1311760001114	AsnC family; Region: AsnC_trans_reg; pfam01037
1311760001115	ribonuclease D; Provisional; Region: PRK10829
1311760001116	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1311760001117	catalytic site [active]
1311760001118	putative active site [active]
1311760001119	putative substrate binding site [chemical binding]; other site
1311760001120	HRDC domain; Region: HRDC; pfam00570
1311760001121	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1311760001122	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1311760001123	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1311760001124	AAA domain; Region: AAA_26; pfam13500
1311760001125	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1311760001126	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1311760001127	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760001128	S-adenosylmethionine binding site [chemical binding]; other site
1311760001129	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1311760001130	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1311760001131	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1311760001132	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1311760001133	putative substrate binding pocket [chemical binding]; other site
1311760001134	dimer interface [polypeptide binding]; other site
1311760001135	phosphate binding site [ion binding]; other site
1311760001136	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1311760001137	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1311760001138	active site
1311760001139	interdomain interaction site; other site
1311760001140	putative metal-binding site [ion binding]; other site
1311760001141	nucleotide binding site [chemical binding]; other site
1311760001142	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1311760001143	domain I; other site
1311760001144	DNA binding groove [nucleotide binding]
1311760001145	phosphate binding site [ion binding]; other site
1311760001146	domain II; other site
1311760001147	domain III; other site
1311760001148	nucleotide binding site [chemical binding]; other site
1311760001149	catalytic site [active]
1311760001150	domain IV; other site
1311760001151	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760001152	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760001153	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1311760001154	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1311760001155	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1311760001156	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760001157	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1311760001158	putative effector binding pocket; other site
1311760001159	dimerization interface [polypeptide binding]; other site
1311760001160	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1311760001161	zinc binding site [ion binding]; other site
1311760001162	putative ligand binding site [chemical binding]; other site
1311760001163	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1311760001164	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1311760001165	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1311760001166	C-terminal domain interface [polypeptide binding]; other site
1311760001167	putative GSH binding site (G-site) [chemical binding]; other site
1311760001168	dimer interface [polypeptide binding]; other site
1311760001169	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1311760001170	dimer interface [polypeptide binding]; other site
1311760001171	N-terminal domain interface [polypeptide binding]; other site
1311760001172	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1311760001173	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1311760001174	active site
1311760001175	homodimer interface [polypeptide binding]; other site
1311760001176	homotetramer interface [polypeptide binding]; other site
1311760001177	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1311760001178	ATP-grasp domain; Region: ATP-grasp; pfam02222
1311760001179	excinuclease ABC subunit B; Provisional; Region: PRK05298
1311760001180	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760001181	ATP binding site [chemical binding]; other site
1311760001182	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760001183	nucleotide binding region [chemical binding]; other site
1311760001184	ATP-binding site [chemical binding]; other site
1311760001185	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1311760001186	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1311760001187	Imelysin; Region: Peptidase_M75; pfam09375
1311760001188	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1311760001189	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1311760001190	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1311760001191	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1311760001192	active site
1311760001193	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1311760001194	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
1311760001195	putative active site [active]
1311760001196	exonuclease I; Provisional; Region: sbcB; PRK11779
1311760001197	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1311760001198	active site
1311760001199	catalytic site [active]
1311760001200	substrate binding site [chemical binding]; other site
1311760001201	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1311760001202	Phage-related protein, tail component [Function unknown]; Region: COG4723
1311760001203	Phage-related protein [Function unknown]; Region: gp18; COG4672
1311760001204	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1311760001205	Phage minor tail protein; Region: Phage_min_tail; cl01940
1311760001206	YcfA-like protein; Region: YcfA; pfam07927
1311760001207	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
1311760001208	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1311760001209	Phage major tail protein 2; Region: Phage_tail_2; cl11463
1311760001210	Encapsulating protein for peroxidase; Region: Linocin_M18; cl17804
1311760001211	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1311760001212	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
1311760001213	Phage terminase large subunit; Region: Terminase_3; cl12054
1311760001214	Terminase-like family; Region: Terminase_6; pfam03237
1311760001215	Terminase small subunit; Region: Terminase_2; pfam03592
1311760001216	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1311760001217	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1311760001218	catalytic residues [active]
1311760001219	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1311760001220	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1311760001221	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1311760001222	MT-A70; Region: MT-A70; cl01947
1311760001223	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1311760001224	replicative DNA helicase; Region: DnaB; TIGR00665
1311760001225	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1311760001226	Walker A motif; other site
1311760001227	ATP binding site [chemical binding]; other site
1311760001228	Walker B motif; other site
1311760001229	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
1311760001230	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001231	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1311760001232	non-specific DNA binding site [nucleotide binding]; other site
1311760001233	salt bridge; other site
1311760001234	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001235	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001236	non-specific DNA binding site [nucleotide binding]; other site
1311760001237	salt bridge; other site
1311760001238	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001239	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760001240	Catalytic site [active]
1311760001241	Haemolysin XhlA; Region: XhlA; pfam10779
1311760001242	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760001243	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760001244	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760001245	Integrase core domain; Region: rve; pfam00665
1311760001246	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760001247	Integrase core domain; Region: rve_3; pfam13683
1311760001248	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001249	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001250	salt bridge; other site
1311760001251	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1311760001252	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1311760001253	metal binding site [ion binding]; metal-binding site
1311760001254	RecT family; Region: RecT; pfam03837
1311760001255	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1311760001256	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1311760001257	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u3; cd11540
1311760001258	putative metal binding site [ion binding]; other site
1311760001259	KilA-N domain; Region: KilA-N; pfam04383
1311760001260	LexA regulated protein; Provisional; Region: PRK11675
1311760001261	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
1311760001262	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1311760001263	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
1311760001264	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1311760001265	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760001266	active site
1311760001267	DNA binding site [nucleotide binding]
1311760001268	Int/Topo IB signature motif; other site
1311760001269	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1311760001270	5S rRNA interface [nucleotide binding]; other site
1311760001271	CTC domain interface [polypeptide binding]; other site
1311760001272	L16 interface [polypeptide binding]; other site
1311760001273	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1311760001274	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1311760001275	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1311760001276	putative NAD(P) binding site [chemical binding]; other site
1311760001277	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
1311760001278	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1311760001279	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1311760001280	dimer interface [polypeptide binding]; other site
1311760001281	FMN binding site [chemical binding]; other site
1311760001282	NADPH bind site [chemical binding]; other site
1311760001283	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1311760001284	Transglycosylase; Region: Transgly; cl17702
1311760001285	Trp operon repressor; Provisional; Region: PRK01381
1311760001286	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1311760001287	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1311760001288	DNA polymerase I; Provisional; Region: PRK05755
1311760001289	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1311760001290	active site
1311760001291	metal binding site 1 [ion binding]; metal-binding site
1311760001292	putative 5' ssDNA interaction site; other site
1311760001293	metal binding site 3; metal-binding site
1311760001294	metal binding site 2 [ion binding]; metal-binding site
1311760001295	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1311760001296	putative DNA binding site [nucleotide binding]; other site
1311760001297	putative metal binding site [ion binding]; other site
1311760001298	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1311760001299	active site
1311760001300	catalytic site [active]
1311760001301	substrate binding site [chemical binding]; other site
1311760001302	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1311760001303	active site
1311760001304	DNA binding site [nucleotide binding]
1311760001305	catalytic site [active]
1311760001306	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1311760001307	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001308	non-specific DNA binding site [nucleotide binding]; other site
1311760001309	salt bridge; other site
1311760001310	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001311	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760001312	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760001313	Catalytic site [active]
1311760001314	Haemolysin XhlA; Region: XhlA; pfam10779
1311760001315	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760001316	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760001317	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760001318	Integrase core domain; Region: rve; pfam00665
1311760001319	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760001320	Integrase core domain; Region: rve_3; pfam13683
1311760001321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1311760001322	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1311760001323	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1311760001324	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1311760001325	substrate binding site [chemical binding]; other site
1311760001326	active site
1311760001327	catalytic residues [active]
1311760001328	heterodimer interface [polypeptide binding]; other site
1311760001329	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1311760001330	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1311760001331	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760001332	catalytic residue [active]
1311760001333	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1311760001334	malonic semialdehyde reductase; Provisional; Region: PRK10538
1311760001335	putative NAD(P) binding site [chemical binding]; other site
1311760001336	homotetramer interface [polypeptide binding]; other site
1311760001337	homodimer interface [polypeptide binding]; other site
1311760001338	active site
1311760001339	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1311760001340	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1311760001341	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1311760001342	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1311760001343	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1311760001344	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1311760001345	putative active site [active]
1311760001346	putative substrate binding site [chemical binding]; other site
1311760001347	putative cosubstrate binding site; other site
1311760001348	catalytic site [active]
1311760001349	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1311760001350	putative active site [active]
1311760001351	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
1311760001352	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
1311760001353	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1311760001354	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1311760001355	dimer interface [polypeptide binding]; other site
1311760001356	putative anticodon binding site; other site
1311760001357	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1311760001358	motif 1; other site
1311760001359	active site
1311760001360	motif 2; other site
1311760001361	motif 3; other site
1311760001362	ribonuclease G; Provisional; Region: PRK11712
1311760001363	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1311760001364	homodimer interface [polypeptide binding]; other site
1311760001365	oligonucleotide binding site [chemical binding]; other site
1311760001366	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1311760001367	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-C; cd09721
1311760001368	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cd09637
1311760001369	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
1311760001370	CRISPR/Cas system-associated protein Cas8c; Region: Cas8c_I-C; cd09757
1311760001371	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-C; cd09752
1311760001372	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1311760001373	Domain of unknown function DUF87; Region: DUF87; pfam01935
1311760001374	HerA helicase [Replication, recombination, and repair]; Region: COG0433
1311760001375	HerA helicase [Replication, recombination, and repair]; Region: COG0433
1311760001376	Domain of unknown function DUF87; Region: DUF87; pfam01935
1311760001377	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1311760001378	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1311760001379	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1311760001380	Probable transposase; Region: OrfB_IS605; pfam01385
1311760001381	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1311760001382	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1311760001383	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1311760001384	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1311760001385	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1311760001386	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
1311760001387	uncharacterized domain; Region: TIGR00702
1311760001388	YcaO-like family; Region: YcaO; pfam02624
1311760001389	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1311760001390	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760001391	S-adenosylmethionine binding site [chemical binding]; other site
1311760001392	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1311760001393	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760001394	Mg2+ binding site [ion binding]; other site
1311760001395	G-X-G motif; other site
1311760001396	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1311760001397	anchoring element; other site
1311760001398	dimer interface [polypeptide binding]; other site
1311760001399	ATP binding site [chemical binding]; other site
1311760001400	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1311760001401	active site
1311760001402	putative metal-binding site [ion binding]; other site
1311760001403	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1311760001404	Restriction endonuclease [Defense mechanisms]; Region: COG3587
1311760001405	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760001406	ATP binding site [chemical binding]; other site
1311760001407	putative Mg++ binding site [ion binding]; other site
1311760001408	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1311760001409	DNA methylase; Region: N6_N4_Mtase; pfam01555
1311760001410	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1311760001411	UbiA prenyltransferase family; Region: UbiA; pfam01040
1311760001412	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1311760001413	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1311760001414	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760001415	adenylosuccinate lyase; Provisional; Region: PRK09285
1311760001416	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1311760001417	tetramer interface [polypeptide binding]; other site
1311760001418	active site
1311760001419	putative lysogenization regulator; Reviewed; Region: PRK00218
1311760001420	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1311760001421	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1311760001422	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760001423	Walker A/P-loop; other site
1311760001424	ATP binding site [chemical binding]; other site
1311760001425	Q-loop/lid; other site
1311760001426	ABC transporter signature motif; other site
1311760001427	Walker B; other site
1311760001428	D-loop; other site
1311760001429	H-loop/switch region; other site
1311760001430	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1311760001431	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1311760001432	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760001433	Walker A/P-loop; other site
1311760001434	ATP binding site [chemical binding]; other site
1311760001435	Q-loop/lid; other site
1311760001436	ABC transporter signature motif; other site
1311760001437	Walker B; other site
1311760001438	D-loop; other site
1311760001439	H-loop/switch region; other site
1311760001440	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1311760001441	Family of unknown function (DUF490); Region: DUF490; pfam04357
1311760001442	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1311760001443	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760001444	Surface antigen; Region: Bac_surface_Ag; pfam01103
1311760001445	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1311760001446	NodB motif; other site
1311760001447	putative active site [active]
1311760001448	putative catalytic site [active]
1311760001449	Zn binding site [ion binding]; other site
1311760001450	AmiB activator; Provisional; Region: PRK11637
1311760001451	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cl00240
1311760001452	Peptidase family M23; Region: Peptidase_M23; pfam01551
1311760001453	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1311760001454	catalytic core [active]
1311760001455	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1311760001456	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1311760001457	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1311760001458	hinge region; other site
1311760001459	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1311760001460	putative nucleotide binding site [chemical binding]; other site
1311760001461	uridine monophosphate binding site [chemical binding]; other site
1311760001462	homohexameric interface [polypeptide binding]; other site
1311760001463	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1311760001464	Sulfatase; Region: Sulfatase; cl17466
1311760001465	elongation factor Ts; Provisional; Region: tsf; PRK09377
1311760001466	UBA/TS-N domain; Region: UBA; pfam00627
1311760001467	Elongation factor TS; Region: EF_TS; pfam00889
1311760001468	Elongation factor TS; Region: EF_TS; pfam00889
1311760001469	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1311760001470	rRNA interaction site [nucleotide binding]; other site
1311760001471	S8 interaction site; other site
1311760001472	putative laminin-1 binding site; other site
1311760001473	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1311760001474	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1311760001475	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1311760001476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760001477	dimer interface [polypeptide binding]; other site
1311760001478	conserved gate region; other site
1311760001479	putative PBP binding loops; other site
1311760001480	ABC-ATPase subunit interface; other site
1311760001481	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760001482	dimer interface [polypeptide binding]; other site
1311760001483	conserved gate region; other site
1311760001484	putative PBP binding loops; other site
1311760001485	ABC-ATPase subunit interface; other site
1311760001486	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1311760001487	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1311760001488	Walker A/P-loop; other site
1311760001489	ATP binding site [chemical binding]; other site
1311760001490	Q-loop/lid; other site
1311760001491	ABC transporter signature motif; other site
1311760001492	Walker B; other site
1311760001493	D-loop; other site
1311760001494	H-loop/switch region; other site
1311760001495	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1311760001496	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1311760001497	catalytic residues [active]
1311760001498	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1311760001499	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1311760001500	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1311760001501	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1311760001502	ATP binding site [chemical binding]; other site
1311760001503	Mg++ binding site [ion binding]; other site
1311760001504	motif III; other site
1311760001505	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760001506	nucleotide binding region [chemical binding]; other site
1311760001507	ATP-binding site [chemical binding]; other site
1311760001508	Recombination protein O N terminal; Region: RecO_N; pfam11967
1311760001509	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1311760001510	Recombination protein O C terminal; Region: RecO_C; pfam02565
1311760001511	GTPase Era; Reviewed; Region: era; PRK00089
1311760001512	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1311760001513	G1 box; other site
1311760001514	GTP/Mg2+ binding site [chemical binding]; other site
1311760001515	Switch I region; other site
1311760001516	G2 box; other site
1311760001517	Switch II region; other site
1311760001518	G3 box; other site
1311760001519	G4 box; other site
1311760001520	G5 box; other site
1311760001521	KH domain; Region: KH_2; pfam07650
1311760001522	ribonuclease III; Reviewed; Region: rnc; PRK00102
1311760001523	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1311760001524	dimerization interface [polypeptide binding]; other site
1311760001525	active site
1311760001526	metal binding site [ion binding]; metal-binding site
1311760001527	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1311760001528	dsRNA binding site [nucleotide binding]; other site
1311760001529	signal peptidase I; Provisional; Region: PRK10861
1311760001530	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1311760001531	Catalytic site [active]
1311760001532	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1311760001533	GTP-binding protein LepA; Provisional; Region: PRK05433
1311760001534	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1311760001535	G1 box; other site
1311760001536	putative GEF interaction site [polypeptide binding]; other site
1311760001537	GTP/Mg2+ binding site [chemical binding]; other site
1311760001538	Switch I region; other site
1311760001539	G2 box; other site
1311760001540	G3 box; other site
1311760001541	Switch II region; other site
1311760001542	G4 box; other site
1311760001543	G5 box; other site
1311760001544	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1311760001545	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1311760001546	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1311760001547	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
1311760001548	homodimer interface [polypeptide binding]; other site
1311760001549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760001550	catalytic residue [active]
1311760001551	Hep_Hag; Region: Hep_Hag; pfam05658
1311760001552	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760001553	trimer interface [polypeptide binding]; other site
1311760001554	Integrase core domain; Region: rve_3; pfam13683
1311760001555	Predicted membrane protein [Function unknown]; Region: COG2259
1311760001556	Uncharacterized low-complexity protein [Function unknown]; Region: COG3767
1311760001557	Protein of unknown function (DUF692); Region: DUF692; pfam05114
1311760001558	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3219
1311760001559	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760001560	RNA polymerase sigma factor; Provisional; Region: PRK12530
1311760001561	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1311760001562	DNA binding residues [nucleotide binding]
1311760001563	Putative zinc-finger; Region: zf-HC2; pfam13490
1311760001564	Phage-related protein, tail component [Function unknown]; Region: COG4723
1311760001565	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1311760001566	MPN+ (JAMM) motif; other site
1311760001567	Zinc-binding site [ion binding]; other site
1311760001568	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1311760001569	NlpC/P60 family; Region: NLPC_P60; cl17555
1311760001570	Phage-related protein [Function unknown]; Region: gp18; COG4672
1311760001571	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1311760001572	Phage-related minor tail protein [Function unknown]; Region: COG5281
1311760001573	tape measure domain; Region: tape_meas_nterm; TIGR02675
1311760001574	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
1311760001575	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1311760001576	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1311760001577	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
1311760001578	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1311760001579	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1311760001580	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1311760001581	Uncharacterized conserved protein (DUF2190); Region: DUF2190; pfam09956
1311760001582	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1311760001583	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1311760001584	oligomer interface [polypeptide binding]; other site
1311760001585	active site residues [active]
1311760001586	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1311760001587	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1311760001588	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1311760001589	RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; Region: RhoGAP; cl02570
1311760001590	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1311760001591	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1311760001592	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1311760001593	Predicted chitinase [General function prediction only]; Region: COG3179
1311760001594	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1311760001595	Lipoprotein GNA1870 C terminal like; Region: Lipoprot_C; pfam08794
1311760001596	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1311760001597	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
1311760001598	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1311760001599	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
1311760001600	Replication protein P; Region: Phage_lambda_P; pfam06992
1311760001601	Helix-turn-helix domain; Region: HTH_36; pfam13730
1311760001602	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1311760001603	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1311760001604	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760001605	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760001606	Catalytic site [active]
1311760001607	Domain of unknown function (DUF4365); Region: DUF4365; pfam14280
1311760001608	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1311760001609	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1311760001610	dimer interface [polypeptide binding]; other site
1311760001611	ssDNA binding site [nucleotide binding]; other site
1311760001612	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1311760001613	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
1311760001614	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1311760001615	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u3; cd11540
1311760001616	putative metal binding site [ion binding]; other site
1311760001617	KilA-N domain; Region: KilA-N; pfam04383
1311760001618	Prophage antirepressor [Transcription]; Region: COG3617
1311760001619	BRO family, N-terminal domain; Region: Bro-N; smart01040
1311760001620	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
1311760001621	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1311760001622	Mu-like prophage protein Com; Region: Mu-like_Com; cl11540
1311760001623	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1311760001624	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
1311760001625	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1311760001626	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760001627	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760001628	active site
1311760001629	DNA binding site [nucleotide binding]
1311760001630	Int/Topo IB signature motif; other site
1311760001631	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1311760001632	Na binding site [ion binding]; other site
1311760001633	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1311760001634	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1311760001635	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1311760001636	OstA-like protein; Region: OstA; pfam03968
1311760001637	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1311760001638	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1311760001639	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760001640	FeS/SAM binding site; other site
1311760001641	HemN C-terminal domain; Region: HemN_C; pfam06969
1311760001642	Protein of unknown function (DUF2489); Region: DUF2489; pfam10675
1311760001643	Der GTPase activator; Provisional; Region: PRK05244
1311760001644	Uncharacterized protein family (UPF0231); Region: UPF0231; pfam06062
1311760001645	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1311760001646	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1311760001647	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1311760001648	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760001649	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1311760001650	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760001651	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1311760001652	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1311760001653	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1311760001654	ATP binding site [chemical binding]; other site
1311760001655	putative Mg++ binding site [ion binding]; other site
1311760001656	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
1311760001657	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1311760001658	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1311760001659	metal binding triad; other site
1311760001660	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1311760001661	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1311760001662	metal binding triad; other site
1311760001663	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1311760001664	YciI-like protein; Reviewed; Region: PRK11370
1311760001665	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1311760001666	intracellular septation protein A; Reviewed; Region: PRK00259
1311760001667	Protein of unknown function, DUF412; Region: DUF412; cl01183
1311760001668	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1311760001669	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1311760001670	ATP binding site [chemical binding]; other site
1311760001671	substrate interface [chemical binding]; other site
1311760001672	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1311760001673	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1311760001674	dimer interface [polypeptide binding]; other site
1311760001675	putative functional site; other site
1311760001676	putative MPT binding site; other site
1311760001677	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1311760001678	AAA domain; Region: AAA_14; pfam13173
1311760001679	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1311760001680	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1311760001681	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760001682	Walker A/P-loop; other site
1311760001683	ATP binding site [chemical binding]; other site
1311760001684	Q-loop/lid; other site
1311760001685	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760001686	ABC transporter signature motif; other site
1311760001687	Walker B; other site
1311760001688	D-loop; other site
1311760001689	ABC transporter; Region: ABC_tran_2; pfam12848
1311760001690	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760001691	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1311760001692	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1311760001693	putative C-terminal domain interface [polypeptide binding]; other site
1311760001694	putative GSH binding site (G-site) [chemical binding]; other site
1311760001695	putative dimer interface [polypeptide binding]; other site
1311760001696	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1311760001697	N-terminal domain interface [polypeptide binding]; other site
1311760001698	dimer interface [polypeptide binding]; other site
1311760001699	substrate binding pocket (H-site) [chemical binding]; other site
1311760001700	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1311760001701	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1311760001702	active site
1311760001703	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1311760001704	catalytic core [active]
1311760001705	hypothetical protein; Provisional; Region: PRK05415
1311760001706	Domain of unknown function (DUF697); Region: DUF697; cl12064
1311760001707	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1311760001708	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1311760001709	FMN binding site [chemical binding]; other site
1311760001710	active site
1311760001711	catalytic residues [active]
1311760001712	substrate binding site [chemical binding]; other site
1311760001713	Predicted membrane protein (DUF2238); Region: DUF2238; cl01464
1311760001714	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1311760001715	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1311760001716	putative metal binding site [ion binding]; other site
1311760001717	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1311760001718	HSP70 interaction site [polypeptide binding]; other site
1311760001719	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1311760001720	ligand binding site [chemical binding]; other site
1311760001721	translocation protein TolB; Provisional; Region: tolB; PRK01742
1311760001722	TolB amino-terminal domain; Region: TolB_N; pfam04052
1311760001723	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1311760001724	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1311760001725	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1311760001726	TolA C-terminal; Region: TolA; pfam06519
1311760001727	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1311760001728	colicin uptake protein TolR; Provisional; Region: PRK11024
1311760001729	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1311760001730	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1311760001731	active site
1311760001732	cyd operon protein YbgE; Region: cyd_oper_ybgE; TIGR02112
1311760001733	Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173
1311760001734	cytochrome d oxidase, subunit II (cydB); Region: cydB; TIGR00203
1311760001735	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1311760001736	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1311760001737	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1311760001738	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1311760001739	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1311760001740	ring oligomerisation interface [polypeptide binding]; other site
1311760001741	ATP/Mg binding site [chemical binding]; other site
1311760001742	stacking interactions; other site
1311760001743	hinge regions; other site
1311760001744	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1311760001745	oligomerisation interface [polypeptide binding]; other site
1311760001746	mobile loop; other site
1311760001747	roof hairpin; other site
1311760001748	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1311760001749	active site
1311760001750	8-oxo-dGMP binding site [chemical binding]; other site
1311760001751	nudix motif; other site
1311760001752	metal binding site [ion binding]; metal-binding site
1311760001753	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1311760001754	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1311760001755	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1311760001756	nucleotide binding region [chemical binding]; other site
1311760001757	ATP-binding site [chemical binding]; other site
1311760001758	SEC-C motif; Region: SEC-C; pfam02810
1311760001759	Protein of unknown function (DUF2547); Region: DUF2547; pfam10818
1311760001760	Protein of unknown function (DUF721); Region: DUF721; cl02324
1311760001761	NlpE N-terminal domain; Region: NlpE; pfam04170
1311760001762	BolA-like protein; Region: BolA; cl00386
1311760001763	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1311760001764	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1311760001765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1311760001766	RNA methyltransferase, RsmE family; Region: TIGR00046
1311760001767	hypothetical protein; Validated; Region: PRK00228
1311760001768	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1311760001769	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1311760001770	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1311760001771	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1311760001772	amino acid carrier protein; Region: agcS; TIGR00835
1311760001773	Staphylococcal nuclease homologues; Region: SNc; smart00318
1311760001774	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
1311760001775	Catalytic site; other site
1311760001776	Excalibur calcium-binding domain; Region: Excalibur; cl05460
1311760001777	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1311760001778	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1311760001779	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1311760001780	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1311760001781	catalytic residue [active]
1311760001782	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1311760001783	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1311760001784	active site
1311760001785	ADP/pyrophosphate binding site [chemical binding]; other site
1311760001786	dimerization interface [polypeptide binding]; other site
1311760001787	allosteric effector site; other site
1311760001788	fructose-1,6-bisphosphate binding site; other site
1311760001789	YwiC-like protein; Region: YwiC; pfam14256
1311760001790	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1311760001791	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1311760001792	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1311760001793	Ligand Binding Site [chemical binding]; other site
1311760001794	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1311760001795	active site residue [active]
1311760001796	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1311760001797	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1311760001798	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1311760001799	homodimer interface [polypeptide binding]; other site
1311760001800	NADP binding site [chemical binding]; other site
1311760001801	substrate binding site [chemical binding]; other site
1311760001802	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1311760001803	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1311760001804	dimer interface [polypeptide binding]; other site
1311760001805	ssDNA binding site [nucleotide binding]; other site
1311760001806	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1311760001807	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760001808	Abi-like protein; Region: Abi_2; pfam07751
1311760001809	RNA polymerases N / 8 kDa subunit; Region: RNA_pol_N; cl00712
1311760001810	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001811	non-specific DNA binding site [nucleotide binding]; other site
1311760001812	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1311760001813	salt bridge; other site
1311760001814	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001815	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760001816	Catalytic site [active]
1311760001817	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
1311760001818	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1311760001819	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1311760001820	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
1311760001821	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760001822	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760001823	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760001824	Haemolysin XhlA; Region: XhlA; pfam10779
1311760001825	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760001826	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760001827	Catalytic site [active]
1311760001828	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1311760001829	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760001830	non-specific DNA binding site [nucleotide binding]; other site
1311760001831	salt bridge; other site
1311760001832	sequence-specific DNA binding site [nucleotide binding]; other site
1311760001833	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1311760001834	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1311760001835	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1311760001836	GDP-binding site [chemical binding]; other site
1311760001837	ACT binding site; other site
1311760001838	IMP binding site; other site
1311760001839	FtsH protease regulator HflC; Provisional; Region: PRK11029
1311760001840	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1311760001841	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1311760001842	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1311760001843	HflK protein; Region: hflK; TIGR01933
1311760001844	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1311760001845	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1311760001846	catalytic residues [active]
1311760001847	OmpW family; Region: OmpW; cl17427
1311760001848	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1311760001849	Clp amino terminal domain; Region: Clp_N; pfam02861
1311760001850	Clp amino terminal domain; Region: Clp_N; pfam02861
1311760001851	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760001852	Walker A motif; other site
1311760001853	ATP binding site [chemical binding]; other site
1311760001854	Walker B motif; other site
1311760001855	arginine finger; other site
1311760001856	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760001857	Walker A motif; other site
1311760001858	ATP binding site [chemical binding]; other site
1311760001859	Walker B motif; other site
1311760001860	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1311760001861	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1311760001862	substrate binding site [chemical binding]; other site
1311760001863	THF binding site; other site
1311760001864	zinc-binding site [ion binding]; other site
1311760001865	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1311760001866	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1311760001867	transmembrane helices; other site
1311760001868	cytidine deaminase; Provisional; Region: PRK09027
1311760001869	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1311760001870	active site
1311760001871	catalytic motif [active]
1311760001872	Zn binding site [ion binding]; other site
1311760001873	Cytidine and deoxycytidylate deaminase zinc-binding region; Region: dCMP_cyt_deam_2; pfam08211
1311760001874	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1311760001875	EamA-like transporter family; Region: EamA; pfam00892
1311760001876	EamA-like transporter family; Region: EamA; pfam00892
1311760001877	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1311760001878	homooctamer interface [polypeptide binding]; other site
1311760001879	active site
1311760001880	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1311760001881	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1311760001882	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760001883	ATP binding site [chemical binding]; other site
1311760001884	Mg2+ binding site [ion binding]; other site
1311760001885	G-X-G motif; other site
1311760001886	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1311760001887	anchoring element; other site
1311760001888	dimer interface [polypeptide binding]; other site
1311760001889	ATP binding site [chemical binding]; other site
1311760001890	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
1311760001891	active site
1311760001892	putative metal-binding site [ion binding]; other site
1311760001893	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1311760001894	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1311760001895	HicB family; Region: HicB; pfam05534
1311760001896	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1311760001897	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1311760001898	DNA binding residues [nucleotide binding]
1311760001899	dimer interface [polypeptide binding]; other site
1311760001900	copper binding site [ion binding]; other site
1311760001901	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1311760001902	metal-binding site [ion binding]
1311760001903	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1311760001904	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1311760001905	metal-binding site [ion binding]
1311760001906	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1311760001907	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760001908	motif II; other site
1311760001909	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1311760001910	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1311760001911	dimerization interface 3.5A [polypeptide binding]; other site
1311760001912	active site
1311760001913	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1311760001914	homodecamer interface [polypeptide binding]; other site
1311760001915	active site
1311760001916	putative catalytic site residues [active]
1311760001917	zinc binding site [ion binding]; other site
1311760001918	GTP-CH-I/GFRP interaction surface; other site
1311760001919	3-deoxy-D-manno-octulosonic-acid kinase; Reviewed; Region: PRK01723
1311760001920	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; pfam06293
1311760001921	antiporter inner membrane protein; Provisional; Region: PRK11670
1311760001922	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1311760001923	Walker A motif; other site
1311760001924	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1311760001925	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1311760001926	peptide binding site [polypeptide binding]; other site
1311760001927	hypothetical protein; Provisional; Region: PRK11111
1311760001928	periplasmic folding chaperone; Provisional; Region: PRK10788
1311760001929	SurA N-terminal domain; Region: SurA_N_3; cl07813
1311760001930	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1311760001931	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1311760001932	16S/18S rRNA binding site [nucleotide binding]; other site
1311760001933	S13e-L30e interaction site [polypeptide binding]; other site
1311760001934	25S rRNA binding site [nucleotide binding]; other site
1311760001935	Protein of unknown function (DUF808); Region: DUF808; pfam05661
1311760001936	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemY; COG3071
1311760001937	HemY protein N-terminus; Region: HemY_N; pfam07219
1311760001938	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760001939	TPR motif; other site
1311760001940	binding surface
1311760001941	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1311760001942	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1311760001943	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1311760001944	active site
1311760001945	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1311760001946	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1311760001947	domain interfaces; other site
1311760001948	active site
1311760001949	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1311760001950	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1311760001951	putative catalytic cysteine [active]
1311760001952	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1311760001953	putative active site [active]
1311760001954	metal binding site [ion binding]; metal-binding site
1311760001955	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1311760001956	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1311760001957	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1311760001958	Spore germination protein; Region: Spore_permease; cl17796
1311760001959	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1311760001960	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1311760001961	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1311760001962	catalytic site [active]
1311760001963	putative active site [active]
1311760001964	putative substrate binding site [chemical binding]; other site
1311760001965	dimer interface [polypeptide binding]; other site
1311760001966	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1311760001967	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1311760001968	active site
1311760001969	(T/H)XGH motif; other site
1311760001970	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1311760001971	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1311760001972	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1311760001973	putative protease; Provisional; Region: PRK15452
1311760001974	Peptidase family U32; Region: Peptidase_U32; pfam01136
1311760001975	Cytochrome b562; Region: Cytochrom_B562; pfam07361
1311760001976	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1311760001977	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1311760001978	putative active site [active]
1311760001979	putative PHP Thumb interface [polypeptide binding]; other site
1311760001980	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1311760001981	generic binding surface II; other site
1311760001982	generic binding surface I; other site
1311760001983	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1311760001984	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1311760001985	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1311760001986	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1311760001987	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1311760001988	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1311760001989	interface (dimer of trimers) [polypeptide binding]; other site
1311760001990	Substrate-binding/catalytic site; other site
1311760001991	Zn-binding sites [ion binding]; other site
1311760001992	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1311760001993	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1311760001994	dimer interface [polypeptide binding]; other site
1311760001995	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760001996	catalytic residue [active]
1311760001997	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1311760001998	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1311760001999	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1311760002000	RNA binding site [nucleotide binding]; other site
1311760002001	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1311760002002	multimer interface [polypeptide binding]; other site
1311760002003	Walker A motif; other site
1311760002004	ATP binding site [chemical binding]; other site
1311760002005	Walker B motif; other site
1311760002006	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1311760002007	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1311760002008	putative active site [active]
1311760002009	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1311760002010	putative active site [active]
1311760002011	F0F1 ATP synthase subunit B'; Validated; Region: PRK07353
1311760002012	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1311760002013	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1311760002014	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
1311760002015	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1311760002016	catalytic core [active]
1311760002017	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1311760002018	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
1311760002019	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1311760002020	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1311760002021	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1311760002022	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1311760002023	active site
1311760002024	phosphorylation site [posttranslational modification]
1311760002025	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1311760002026	active pocket/dimerization site; other site
1311760002027	active site
1311760002028	phosphorylation site [posttranslational modification]
1311760002029	acetylornithine aminotransferase; Provisional; Region: PRK02627
1311760002030	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1311760002031	inhibitor-cofactor binding pocket; inhibition site
1311760002032	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760002033	catalytic residue [active]
1311760002034	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
1311760002035	nucleotide binding site [chemical binding]; other site
1311760002036	homohexameric interface [polypeptide binding]; other site
1311760002037	N-acetyl-L-glutamate binding site [chemical binding]; other site
1311760002038	N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863
1311760002039	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1311760002040	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1311760002041	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1311760002042	putative C-terminal domain interface [polypeptide binding]; other site
1311760002043	putative GSH binding site (G-site) [chemical binding]; other site
1311760002044	putative dimer interface [polypeptide binding]; other site
1311760002045	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1311760002046	N-terminal domain interface [polypeptide binding]; other site
1311760002047	dimer interface [polypeptide binding]; other site
1311760002048	substrate binding pocket (H-site) [chemical binding]; other site
1311760002049	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1311760002050	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1311760002051	putative active site [active]
1311760002052	putative FMN binding site [chemical binding]; other site
1311760002053	putative substrate binding site [chemical binding]; other site
1311760002054	putative catalytic residue [active]
1311760002055	Nitroreductase family. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source...; Region: Nitroreductase; cd02136
1311760002056	putative FMN binding site [chemical binding]; other site
1311760002057	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1311760002058	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1311760002059	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1311760002060	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1311760002061	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760002062	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1311760002063	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1311760002064	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1311760002065	intersubunit interface [polypeptide binding]; other site
1311760002066	active site
1311760002067	catalytic residue [active]
1311760002068	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1311760002069	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1311760002070	Nucleoside recognition; Region: Gate; pfam07670
1311760002071	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1311760002072	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1311760002073	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1311760002074	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1311760002075	active site
1311760002076	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1311760002077	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1311760002078	active site
1311760002079	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1311760002080	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1311760002081	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
1311760002082	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1311760002083	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1311760002084	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1311760002085	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1311760002086	active site
1311760002087	homodimer interface [polypeptide binding]; other site
1311760002088	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1311760002089	ligand binding site; other site
1311760002090	tetramer interface; other site
1311760002091	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1311760002092	active site
1311760002093	catalytic triad [active]
1311760002094	oxyanion hole [active]
1311760002095	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1311760002096	NeuB family; Region: NeuB; pfam03102
1311760002097	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1311760002098	NeuB binding interface [polypeptide binding]; other site
1311760002099	putative substrate binding site [chemical binding]; other site
1311760002100	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1311760002101	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1311760002102	putative trimer interface [polypeptide binding]; other site
1311760002103	putative CoA binding site [chemical binding]; other site
1311760002104	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1311760002105	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1311760002106	putative active site [active]
1311760002107	primosome assembly protein PriA; Validated; Region: PRK05580
1311760002108	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760002109	ATP binding site [chemical binding]; other site
1311760002110	putative Mg++ binding site [ion binding]; other site
1311760002111	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1311760002112	nucleotide binding region [chemical binding]; other site
1311760002113	ATP-binding site [chemical binding]; other site
1311760002114	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1311760002115	EamA-like transporter family; Region: EamA; pfam00892
1311760002116	aminotransferase AlaT; Validated; Region: PRK09265
1311760002117	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1311760002118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760002119	homodimer interface [polypeptide binding]; other site
1311760002120	catalytic residue [active]
1311760002121	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
1311760002122	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1311760002123	Integrase core domain; Region: rve; pfam00665
1311760002124	Integrase core domain; Region: rve_3; pfam13683
1311760002125	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760002126	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760002127	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1311760002128	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760002129	FeS/SAM binding site; other site
1311760002130	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1311760002131	active site
1311760002132	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1311760002133	Ligand Binding Site [chemical binding]; other site
1311760002134	Membrane fusogenic activity; Region: BMFP; cl01115
1311760002135	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1311760002136	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1311760002137	active site
1311760002138	dimer interface [polypeptide binding]; other site
1311760002139	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1311760002140	dimer interface [polypeptide binding]; other site
1311760002141	active site
1311760002142	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1311760002143	AAA domain; Region: AAA_30; pfam13604
1311760002144	Family description; Region: UvrD_C_2; pfam13538
1311760002145	alanine racemase; Reviewed; Region: alr; PRK00053
1311760002146	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1311760002147	active site
1311760002148	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1311760002149	substrate binding site [chemical binding]; other site
1311760002150	catalytic residues [active]
1311760002151	dimer interface [polypeptide binding]; other site
1311760002152	superoxide dismutase; Provisional; Region: PRK10925
1311760002153	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1311760002154	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1311760002155	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1311760002156	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1311760002157	putative catalytic residues [active]
1311760002158	putative nucleotide binding site [chemical binding]; other site
1311760002159	putative aspartate binding site [chemical binding]; other site
1311760002160	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1311760002161	dimer interface [polypeptide binding]; other site
1311760002162	putative threonine allosteric regulatory site; other site
1311760002163	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1311760002164	putative threonine allosteric regulatory site; other site
1311760002165	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1311760002166	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1311760002167	homoserine kinase; Provisional; Region: PRK01212
1311760002168	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1311760002169	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1311760002170	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1311760002171	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1311760002172	active site
1311760002173	HIGH motif; other site
1311760002174	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1311760002175	KMSKS motif; other site
1311760002176	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1311760002177	tRNA binding surface [nucleotide binding]; other site
1311760002178	anticodon binding site; other site
1311760002179	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1311760002180	substrate binding site [chemical binding]; other site
1311760002181	Membrane transport protein; Region: Mem_trans; cl09117
1311760002182	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1311760002183	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1311760002184	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1311760002185	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1311760002186	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1311760002187	molybdopterin cofactor binding site; other site
1311760002188	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1311760002189	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1311760002190	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1311760002191	Cytochrome b subunit of formate dehydrogenase [Energy production and conversion]; Region: FdnI; COG2864
1311760002192	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1311760002193	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1311760002194	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1311760002195	glutathione reductase; Validated; Region: PRK06116
1311760002196	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1311760002197	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1311760002198	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1311760002199	hypothetical protein; Provisional; Region: PRK05208
1311760002200	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1311760002201	dimer interface [polypeptide binding]; other site
1311760002202	FMN binding site [chemical binding]; other site
1311760002203	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SapF; COG4167
1311760002204	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760002205	Walker A/P-loop; other site
1311760002206	ATP binding site [chemical binding]; other site
1311760002207	Q-loop/lid; other site
1311760002208	ABC transporter signature motif; other site
1311760002209	Walker B; other site
1311760002210	D-loop; other site
1311760002211	H-loop/switch region; other site
1311760002212	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1311760002213	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1311760002214	active site
1311760002215	intersubunit interface [polypeptide binding]; other site
1311760002216	zinc binding site [ion binding]; other site
1311760002217	Na+ binding site [ion binding]; other site
1311760002218	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1311760002219	Phosphoglycerate kinase; Region: PGK; pfam00162
1311760002220	substrate binding site [chemical binding]; other site
1311760002221	hinge regions; other site
1311760002222	ADP binding site [chemical binding]; other site
1311760002223	catalytic site [active]
1311760002224	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1311760002225	Na2 binding site [ion binding]; other site
1311760002226	putative substrate binding site 1 [chemical binding]; other site
1311760002227	Na binding site 1 [ion binding]; other site
1311760002228	putative substrate binding site 2 [chemical binding]; other site
1311760002229	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1311760002230	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1311760002231	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1311760002232	active site
1311760002233	dimer interface [polypeptide binding]; other site
1311760002234	metal binding site [ion binding]; metal-binding site
1311760002235	shikimate kinase; Reviewed; Region: aroK; PRK00131
1311760002236	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1311760002237	ADP binding site [chemical binding]; other site
1311760002238	magnesium binding site [ion binding]; other site
1311760002239	putative shikimate binding site; other site
1311760002240	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1311760002241	Transglycosylase; Region: Transgly; pfam00912
1311760002242	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1311760002243	Competence protein A; Region: Competence_A; pfam11104
1311760002244	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
1311760002245	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1311760002246	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1311760002247	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1311760002248	putative RNA binding site [nucleotide binding]; other site
1311760002249	thiamine monophosphate kinase; Provisional; Region: PRK05731
1311760002250	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1311760002251	ATP binding site [chemical binding]; other site
1311760002252	dimerization interface [polypeptide binding]; other site
1311760002253	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1311760002254	tetramer interfaces [polypeptide binding]; other site
1311760002255	binuclear metal-binding site [ion binding]; other site
1311760002256	LysE type translocator; Region: LysE; cl00565
1311760002257	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1311760002258	RuvA N terminal domain; Region: RuvA_N; pfam01330
1311760002259	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1311760002260	helix-hairpin-helix signature motif; other site
1311760002261	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1311760002262	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1311760002263	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760002264	Walker A motif; other site
1311760002265	ATP binding site [chemical binding]; other site
1311760002266	Walker B motif; other site
1311760002267	arginine finger; other site
1311760002268	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1311760002269	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002270	dimer interface [polypeptide binding]; other site
1311760002271	conserved gate region; other site
1311760002272	putative PBP binding loops; other site
1311760002273	ABC-ATPase subunit interface; other site
1311760002274	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1311760002275	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002276	dimer interface [polypeptide binding]; other site
1311760002277	conserved gate region; other site
1311760002278	putative PBP binding loops; other site
1311760002279	ABC-ATPase subunit interface; other site
1311760002280	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1311760002281	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1311760002282	substrate binding pocket [chemical binding]; other site
1311760002283	membrane-bound complex binding site; other site
1311760002284	hinge residues; other site
1311760002285	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1311760002286	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1311760002287	Walker A/P-loop; other site
1311760002288	ATP binding site [chemical binding]; other site
1311760002289	Q-loop/lid; other site
1311760002290	ABC transporter signature motif; other site
1311760002291	Walker B; other site
1311760002292	D-loop; other site
1311760002293	H-loop/switch region; other site
1311760002294	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1311760002295	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1311760002296	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1311760002297	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1311760002298	DsbD alpha interface [polypeptide binding]; other site
1311760002299	catalytic residues [active]
1311760002300	Protein of unknown function, DUF462; Region: DUF462; cl01190
1311760002301	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1311760002302	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1311760002303	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1311760002304	acyl-activating enzyme (AAE) consensus motif; other site
1311760002305	putative AMP binding site [chemical binding]; other site
1311760002306	putative active site [active]
1311760002307	putative CoA binding site [chemical binding]; other site
1311760002308	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1311760002309	homotrimer interaction site [polypeptide binding]; other site
1311760002310	putative active site [active]
1311760002311	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1311760002312	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1311760002313	homodimer interface [polypeptide binding]; other site
1311760002314	substrate-cofactor binding pocket; other site
1311760002315	catalytic residue [active]
1311760002316	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1311760002317	putative GSH binding site [chemical binding]; other site
1311760002318	catalytic residues [active]
1311760002319	recombination protein RecR; Reviewed; Region: recR; PRK00076
1311760002320	RecR protein; Region: RecR; pfam02132
1311760002321	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1311760002322	putative active site [active]
1311760002323	putative metal-binding site [ion binding]; other site
1311760002324	tetramer interface [polypeptide binding]; other site
1311760002325	hypothetical protein; Validated; Region: PRK00153
1311760002326	recF protein; Region: recf; TIGR00611
1311760002327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760002328	Walker A/P-loop; other site
1311760002329	ATP binding site [chemical binding]; other site
1311760002330	Q-loop/lid; other site
1311760002331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760002332	ABC transporter signature motif; other site
1311760002333	Walker B; other site
1311760002334	D-loop; other site
1311760002335	H-loop/switch region; other site
1311760002336	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1311760002337	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
1311760002338	arogenate dehydrogenase; Region: PLN02256
1311760002339	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1311760002340	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1311760002341	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1311760002342	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760002343	putative active site [active]
1311760002344	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1311760002345	pyruvate kinase; Provisional; Region: PRK05826
1311760002346	active site
1311760002347	domain interfaces; other site
1311760002348	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1311760002349	catalytic core [active]
1311760002350	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1311760002351	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1311760002352	FMN binding site [chemical binding]; other site
1311760002353	active site
1311760002354	catalytic residues [active]
1311760002355	substrate binding site [chemical binding]; other site
1311760002356	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1311760002357	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1311760002358	TonB-dependent lactoferrin and transferrin receptors; Region: TonB-tbp-lbp; TIGR01776
1311760002359	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1311760002360	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1311760002361	ligand-binding site [chemical binding]; other site
1311760002362	Transferrin binding protein-like solute binding protein; Region: Lipoprotein_5; pfam01298
1311760002363	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1311760002364	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1311760002365	dimer interface [polypeptide binding]; other site
1311760002366	catalytic site [active]
1311760002367	putative active site [active]
1311760002368	putative substrate binding site [chemical binding]; other site
1311760002369	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1311760002370	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1311760002371	dimer interface [polypeptide binding]; other site
1311760002372	active site
1311760002373	metal binding site [ion binding]; metal-binding site
1311760002374	glutathione binding site [chemical binding]; other site
1311760002375	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1311760002376	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1311760002377	catalytic center binding site [active]
1311760002378	ATP binding site [chemical binding]; other site
1311760002379	poly(A) polymerase; Region: pcnB; TIGR01942
1311760002380	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1311760002381	active site
1311760002382	NTP binding site [chemical binding]; other site
1311760002383	metal binding triad [ion binding]; metal-binding site
1311760002384	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1311760002385	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1311760002386	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1311760002387	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1311760002388	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1311760002389	hypothetical protein; Validated; Region: PRK06886
1311760002390	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1311760002391	active site
1311760002392	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
1311760002393	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1311760002394	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1311760002395	Ligand binding site; other site
1311760002396	oligomer interface; other site
1311760002397	thioredoxin reductase; Provisional; Region: PRK10262
1311760002398	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1311760002399	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1311760002400	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1311760002401	Dak1 domain; Region: Dak1; pfam02733
1311760002402	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1311760002403	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
1311760002404	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1311760002405	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1311760002406	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1311760002407	active site residue [active]
1311760002408	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
1311760002409	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1311760002410	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1311760002411	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1311760002412	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1311760002413	cell division protein ZipA; Provisional; Region: PRK01741
1311760002414	ZipA, C-terminal FtsZ-binding domain; Region: ZipA_C; pfam04354
1311760002415	FtsZ protein binding site [polypeptide binding]; other site
1311760002416	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1311760002417	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1311760002418	nucleotide binding pocket [chemical binding]; other site
1311760002419	K-X-D-G motif; other site
1311760002420	catalytic site [active]
1311760002421	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1311760002422	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1311760002423	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1311760002424	Dimer interface [polypeptide binding]; other site
1311760002425	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1311760002426	Domain of unknown function (DUF4189); Region: DUF4189; pfam13827
1311760002427	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1311760002428	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1311760002429	dimer interface [polypeptide binding]; other site
1311760002430	active site
1311760002431	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1311760002432	adenylate cyclase; Provisional; Region: cyaA; PRK09450
1311760002433	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1311760002434	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1311760002435	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1311760002436	TrkA-N domain; Region: TrkA_N; pfam02254
1311760002437	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1311760002438	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1311760002439	trimer interface; other site
1311760002440	sugar binding site [chemical binding]; other site
1311760002441	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1311760002442	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1311760002443	Walker A/P-loop; other site
1311760002444	ATP binding site [chemical binding]; other site
1311760002445	Q-loop/lid; other site
1311760002446	ABC transporter signature motif; other site
1311760002447	Walker B; other site
1311760002448	D-loop; other site
1311760002449	H-loop/switch region; other site
1311760002450	TOBE domain; Region: TOBE_2; pfam08402
1311760002451	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1311760002452	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1311760002453	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
1311760002454	anticodon binding site; other site
1311760002455	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002456	dimer interface [polypeptide binding]; other site
1311760002457	conserved gate region; other site
1311760002458	putative PBP binding loops; other site
1311760002459	ABC-ATPase subunit interface; other site
1311760002460	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1311760002461	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002462	dimer interface [polypeptide binding]; other site
1311760002463	conserved gate region; other site
1311760002464	putative PBP binding loops; other site
1311760002465	ABC-ATPase subunit interface; other site
1311760002466	alpha-amylase; Reviewed; Region: malS; PRK09505
1311760002467	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1311760002468	active site
1311760002469	catalytic site [active]
1311760002470	transcriptional regulator MalT; Provisional; Region: PRK04841
1311760002471	AAA ATPase domain; Region: AAA_16; pfam13191
1311760002472	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1311760002473	DNA binding residues [nucleotide binding]
1311760002474	dimerization interface [polypeptide binding]; other site
1311760002475	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1311760002476	homodimer interface [polypeptide binding]; other site
1311760002477	maltodextrin phosphorylase; Provisional; Region: PRK14985
1311760002478	active site pocket [active]
1311760002479	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1311760002480	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1311760002481	putative transporter; Validated; Region: PRK03818
1311760002482	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1311760002483	TrkA-C domain; Region: TrkA_C; pfam02080
1311760002484	TrkA-C domain; Region: TrkA_C; pfam02080
1311760002485	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1311760002486	Predicted permease [General function prediction only]; Region: COG2056
1311760002487	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1311760002488	Predicted membrane protein [Function unknown]; Region: COG1288; cl17886
1311760002489	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1311760002490	putative catalytic site [active]
1311760002491	putative phosphate binding site [ion binding]; other site
1311760002492	active site
1311760002493	metal binding site A [ion binding]; metal-binding site
1311760002494	DNA binding site [nucleotide binding]
1311760002495	putative AP binding site [nucleotide binding]; other site
1311760002496	putative metal binding site B [ion binding]; other site
1311760002497	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117
1311760002498	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1311760002499	OstA-like protein; Region: OstA; cl00844
1311760002500	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1311760002501	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1311760002502	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1311760002503	Walker A/P-loop; other site
1311760002504	ATP binding site [chemical binding]; other site
1311760002505	Q-loop/lid; other site
1311760002506	ABC transporter signature motif; other site
1311760002507	Walker B; other site
1311760002508	D-loop; other site
1311760002509	H-loop/switch region; other site
1311760002510	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1311760002511	active site
1311760002512	phosphorylation site [posttranslational modification]
1311760002513	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1311760002514	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1311760002515	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1311760002516	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1311760002517	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1311760002518	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1311760002519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760002520	Walker A/P-loop; other site
1311760002521	ATP binding site [chemical binding]; other site
1311760002522	Q-loop/lid; other site
1311760002523	ABC transporter signature motif; other site
1311760002524	Walker B; other site
1311760002525	D-loop; other site
1311760002526	H-loop/switch region; other site
1311760002527	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1311760002528	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1311760002529	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1311760002530	P loop; other site
1311760002531	GTP binding site [chemical binding]; other site
1311760002532	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1311760002533	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760002534	S-adenosylmethionine binding site [chemical binding]; other site
1311760002535	dsDNA-mimic protein; Reviewed; Region: PRK05094
1311760002536	Flavin Reductases; Region: FlaRed; cl00801
1311760002537	tellurite resistance protein TehB; Provisional; Region: PRK12335
1311760002538	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1311760002539	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760002540	S-adenosylmethionine binding site [chemical binding]; other site
1311760002541	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1311760002542	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1311760002543	dimerization interface [polypeptide binding]; other site
1311760002544	putative ATP binding site [chemical binding]; other site
1311760002545	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
1311760002546	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1311760002547	Aspartase; Region: Aspartase; cd01357
1311760002548	active sites [active]
1311760002549	tetramer interface [polypeptide binding]; other site
1311760002550	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
1311760002551	Part of AAA domain; Region: AAA_19; pfam13245
1311760002552	Family description; Region: UvrD_C_2; pfam13538
1311760002553	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1311760002554	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1311760002555	Walker A/P-loop; other site
1311760002556	ATP binding site [chemical binding]; other site
1311760002557	Q-loop/lid; other site
1311760002558	ABC transporter signature motif; other site
1311760002559	Walker B; other site
1311760002560	D-loop; other site
1311760002561	H-loop/switch region; other site
1311760002562	TOBE domain; Region: TOBE_2; pfam08402
1311760002563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002564	dimer interface [polypeptide binding]; other site
1311760002565	conserved gate region; other site
1311760002566	putative PBP binding loops; other site
1311760002567	ABC-ATPase subunit interface; other site
1311760002568	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1311760002569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002570	dimer interface [polypeptide binding]; other site
1311760002571	conserved gate region; other site
1311760002572	putative PBP binding loops; other site
1311760002573	ABC-ATPase subunit interface; other site
1311760002574	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1311760002575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002576	dimer interface [polypeptide binding]; other site
1311760002577	conserved gate region; other site
1311760002578	putative PBP binding loops; other site
1311760002579	ABC-ATPase subunit interface; other site
1311760002580	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1311760002581	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1311760002582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760002583	dimer interface [polypeptide binding]; other site
1311760002584	conserved gate region; other site
1311760002585	ABC-ATPase subunit interface; other site
1311760002586	ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]; Region: COG4172
1311760002587	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760002588	Walker A/P-loop; other site
1311760002589	ATP binding site [chemical binding]; other site
1311760002590	Q-loop/lid; other site
1311760002591	ABC transporter signature motif; other site
1311760002592	Walker B; other site
1311760002593	D-loop; other site
1311760002594	H-loop/switch region; other site
1311760002595	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1311760002596	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760002597	Walker A/P-loop; other site
1311760002598	ATP binding site [chemical binding]; other site
1311760002599	Q-loop/lid; other site
1311760002600	ABC transporter signature motif; other site
1311760002601	Walker B; other site
1311760002602	D-loop; other site
1311760002603	H-loop/switch region; other site
1311760002604	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1311760002605	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1311760002606	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1311760002607	N-terminal plug; other site
1311760002608	ligand-binding site [chemical binding]; other site
1311760002609	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
1311760002610	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1311760002611	intersubunit interface [polypeptide binding]; other site
1311760002612	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1311760002613	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760002614	ABC-ATPase subunit  interface; other site
1311760002615	dimer interface [polypeptide binding]; other site
1311760002616	putative PBP binding regions; other site
1311760002617	ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG4559
1311760002618	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1311760002619	Walker A/P-loop; other site
1311760002620	ATP binding site [chemical binding]; other site
1311760002621	Q-loop/lid; other site
1311760002622	ABC transporter signature motif; other site
1311760002623	Walker B; other site
1311760002624	D-loop; other site
1311760002625	H-loop/switch region; other site
1311760002626	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1311760002627	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1311760002628	active site
1311760002629	substrate binding site [chemical binding]; other site
1311760002630	cosubstrate binding site; other site
1311760002631	catalytic site [active]
1311760002632	Protein of unknown function, DUF399; Region: DUF399; pfam04187
1311760002633	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1311760002634	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1311760002635	dimer interface [polypeptide binding]; other site
1311760002636	active site
1311760002637	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1311760002638	folate binding site [chemical binding]; other site
1311760002639	methionine synthase; Provisional; Region: PRK01207
1311760002640	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1311760002641	substrate binding site [chemical binding]; other site
1311760002642	THF binding site; other site
1311760002643	zinc-binding site [ion binding]; other site
1311760002644	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
1311760002645	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
1311760002646	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1311760002647	putative methyltransferase; Provisional; Region: PRK10864
1311760002648	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1311760002649	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1311760002650	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1311760002651	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1311760002652	active site
1311760002653	dimerization interface [polypeptide binding]; other site
1311760002654	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1311760002655	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1311760002656	TPP-binding site; other site
1311760002657	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1311760002658	PYR/PP interface [polypeptide binding]; other site
1311760002659	dimer interface [polypeptide binding]; other site
1311760002660	TPP binding site [chemical binding]; other site
1311760002661	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1311760002662	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
1311760002663	Carbon starvation protein CstA; Region: CstA; pfam02554
1311760002664	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1311760002665	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1311760002666	active site
1311760002667	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
1311760002668	conserved cys residue [active]
1311760002669	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760002670	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1311760002671	putative substrate translocation pore; other site
1311760002672	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1311760002673	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1311760002674	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1311760002675	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1311760002676	active site
1311760002677	dimer interface [polypeptide binding]; other site
1311760002678	motif 1; other site
1311760002679	motif 2; other site
1311760002680	motif 3; other site
1311760002681	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1311760002682	anticodon binding site; other site
1311760002683	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1311760002684	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1311760002685	FtsX-like permease family; Region: FtsX; pfam02687
1311760002686	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1311760002687	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1311760002688	Walker A/P-loop; other site
1311760002689	ATP binding site [chemical binding]; other site
1311760002690	Q-loop/lid; other site
1311760002691	ABC transporter signature motif; other site
1311760002692	Walker B; other site
1311760002693	D-loop; other site
1311760002694	H-loop/switch region; other site
1311760002695	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1311760002696	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1311760002697	FtsX-like permease family; Region: FtsX; pfam02687
1311760002698	glycerate dehydrogenase; Provisional; Region: PRK06932
1311760002699	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1311760002700	putative ligand binding site [chemical binding]; other site
1311760002701	putative NAD binding site [chemical binding]; other site
1311760002702	catalytic site [active]
1311760002703	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1311760002704	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1311760002705	Uncharacterized conserved protein [Function unknown]; Region: COG2912
1311760002706	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1311760002707	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1311760002708	binding surface
1311760002709	TPR motif; other site
1311760002710	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1311760002711	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760002712	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
1311760002713	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1311760002714	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1311760002715	RF-1 domain; Region: RF-1; pfam00472
1311760002716	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1311760002717	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1311760002718	glutamine binding [chemical binding]; other site
1311760002719	catalytic triad [active]
1311760002720	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1311760002721	RmuC family; Region: RmuC; pfam02646
1311760002722	para-aminobenzoate synthase component I; Validated; Region: PRK07093
1311760002723	hypothetical protein; Provisional; Region: PRK07101
1311760002724	recombinase A; Provisional; Region: recA; PRK09354
1311760002725	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1311760002726	hexamer interface [polypeptide binding]; other site
1311760002727	Walker A motif; other site
1311760002728	ATP binding site [chemical binding]; other site
1311760002729	Walker B motif; other site
1311760002730	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1311760002731	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1311760002732	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760002733	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1311760002734	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760002735	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760002736	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1311760002737	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1311760002738	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1311760002739	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1311760002740	shikimate binding site; other site
1311760002741	NAD(P) binding site [chemical binding]; other site
1311760002742	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1311760002743	Part of AAA domain; Region: AAA_19; pfam13245
1311760002744	Family description; Region: UvrD_C_2; pfam13538
1311760002745	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1311760002746	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760002747	NAD(P) binding site [chemical binding]; other site
1311760002748	active site
1311760002749	arginine repressor; Provisional; Region: PRK05066
1311760002750	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1311760002751	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1311760002752	malate dehydrogenase; Provisional; Region: PRK05086
1311760002753	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1311760002754	NAD binding site [chemical binding]; other site
1311760002755	dimerization interface [polypeptide binding]; other site
1311760002756	Substrate binding site [chemical binding]; other site
1311760002757	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1311760002758	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1311760002759	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1311760002760	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760002761	motif I; other site
1311760002762	motif II; other site
1311760002763	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760002764	Uncharacterized membrane protein affecting hemolysin expression [General function prediction only]; Region: AhpA; COG3726
1311760002765	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1311760002766	rRNA binding site [nucleotide binding]; other site
1311760002767	predicted 30S ribosome binding site; other site
1311760002768	Predicted flavoproteins [General function prediction only]; Region: COG2081
1311760002769	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1311760002770	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1311760002771	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1311760002772	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1311760002773	Protein of unknown function (DUF3464); Region: DUF3464; pfam11947
1311760002774	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK06901
1311760002775	LexA regulated protein; Provisional; Region: PRK11675
1311760002776	flavodoxin FldA; Validated; Region: PRK09267
1311760002777	ferric uptake regulator; Provisional; Region: fur; PRK09462
1311760002778	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1311760002779	metal binding site 2 [ion binding]; metal-binding site
1311760002780	putative DNA binding helix; other site
1311760002781	metal binding site 1 [ion binding]; metal-binding site
1311760002782	dimer interface [polypeptide binding]; other site
1311760002783	structural Zn2+ binding site [ion binding]; other site
1311760002784	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1311760002785	mce related protein; Region: MCE; pfam02470
1311760002786	mce related protein; Region: MCE; pfam02470
1311760002787	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1311760002788	mce related protein; Region: MCE; pfam02470
1311760002789	mce related protein; Region: MCE; pfam02470
1311760002790	mce related protein; Region: MCE; pfam02470
1311760002791	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1311760002792	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1311760002793	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1311760002794	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1311760002795	Walker A/P-loop; other site
1311760002796	ATP binding site [chemical binding]; other site
1311760002797	Q-loop/lid; other site
1311760002798	ABC transporter signature motif; other site
1311760002799	Walker B; other site
1311760002800	D-loop; other site
1311760002801	H-loop/switch region; other site
1311760002802	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1311760002803	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1311760002804	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760002805	Walker A motif; other site
1311760002806	ATP binding site [chemical binding]; other site
1311760002807	Walker B motif; other site
1311760002808	arginine finger; other site
1311760002809	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1311760002810	DnaA box-binding interface [nucleotide binding]; other site
1311760002811	DNA polymerase III subunit beta; Validated; Region: PRK05643
1311760002812	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1311760002813	putative DNA binding surface [nucleotide binding]; other site
1311760002814	dimer interface [polypeptide binding]; other site
1311760002815	beta-clamp/clamp loader binding surface; other site
1311760002816	beta-clamp/translesion DNA polymerase binding surface; other site
1311760002817	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1311760002818	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1311760002819	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1311760002820	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1311760002821	dimer interface [polypeptide binding]; other site
1311760002822	motif 1; other site
1311760002823	active site
1311760002824	motif 2; other site
1311760002825	motif 3; other site
1311760002826	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1311760002827	anticodon binding site; other site
1311760002828	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1311760002829	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1311760002830	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1311760002831	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760002832	non-specific DNA binding site [nucleotide binding]; other site
1311760002833	salt bridge; other site
1311760002834	sequence-specific DNA binding site [nucleotide binding]; other site
1311760002835	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1311760002836	argininosuccinate lyase; Provisional; Region: PRK04833
1311760002837	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1311760002838	active sites [active]
1311760002839	tetramer interface [polypeptide binding]; other site
1311760002840	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1311760002841	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1311760002842	Ligand Binding Site [chemical binding]; other site
1311760002843	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1311760002844	active site
1311760002845	NTP binding site [chemical binding]; other site
1311760002846	metal binding triad [ion binding]; metal-binding site
1311760002847	antibiotic binding site [chemical binding]; other site
1311760002848	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
1311760002849	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
1311760002850	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1311760002851	ApbE family; Region: ApbE; pfam02424
1311760002852	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1311760002853	active site
1311760002854	NTP binding site [chemical binding]; other site
1311760002855	metal binding triad [ion binding]; metal-binding site
1311760002856	antibiotic binding site [chemical binding]; other site
1311760002857	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
1311760002858	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1311760002859	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1311760002860	FAD binding pocket [chemical binding]; other site
1311760002861	FAD binding motif [chemical binding]; other site
1311760002862	phosphate binding motif [ion binding]; other site
1311760002863	beta-alpha-beta structure motif; other site
1311760002864	NAD binding pocket [chemical binding]; other site
1311760002865	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1311760002866	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1311760002867	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1311760002868	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1311760002869	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
1311760002870	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
1311760002871	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1311760002872	E3 interaction surface; other site
1311760002873	lipoyl attachment site [posttranslational modification]; other site
1311760002874	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1311760002875	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1311760002876	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1311760002877	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1311760002878	CTP synthetase; Validated; Region: pyrG; PRK05380
1311760002879	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1311760002880	Catalytic site [active]
1311760002881	active site
1311760002882	UTP binding site [chemical binding]; other site
1311760002883	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1311760002884	active site
1311760002885	putative oxyanion hole; other site
1311760002886	catalytic triad [active]
1311760002887	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1311760002888	active site
1311760002889	homotetramer interface [polypeptide binding]; other site
1311760002890	homodimer interface [polypeptide binding]; other site
1311760002891	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1311760002892	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760002893	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1311760002894	substrate binding site [chemical binding]; other site
1311760002895	dimerization interface [polypeptide binding]; other site
1311760002896	dUMP phosphatase; Provisional; Region: PRK09449
1311760002897	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760002898	motif II; other site
1311760002899	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1311760002900	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760002901	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1311760002902	dimerization interface [polypeptide binding]; other site
1311760002903	substrate binding pocket [chemical binding]; other site
1311760002904	GTPase RsgA; Reviewed; Region: PRK12288
1311760002905	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1311760002906	RNA binding site [nucleotide binding]; other site
1311760002907	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1311760002908	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1311760002909	GTP/Mg2+ binding site [chemical binding]; other site
1311760002910	G4 box; other site
1311760002911	G5 box; other site
1311760002912	G1 box; other site
1311760002913	Switch I region; other site
1311760002914	G2 box; other site
1311760002915	G3 box; other site
1311760002916	Switch II region; other site
1311760002917	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1311760002918	RNA/DNA hybrid binding site [nucleotide binding]; other site
1311760002919	active site
1311760002920	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1311760002921	nucleotide binding site/active site [active]
1311760002922	HIT family signature motif; other site
1311760002923	catalytic residue [active]
1311760002924	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1311760002925	putative dimer interface [polypeptide binding]; other site
1311760002926	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1311760002927	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1311760002928	Peptidase M15; Region: Peptidase_M15_3; cl01194
1311760002929	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1311760002930	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1311760002931	carboxy-terminal protease; Provisional; Region: PRK11186
1311760002932	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1311760002933	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1311760002934	protein binding site [polypeptide binding]; other site
1311760002935	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1311760002936	Catalytic dyad [active]
1311760002937	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1311760002938	ProQ/FINO family; Region: ProQ; pfam04352
1311760002939	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1311760002940	DNA-binding site [nucleotide binding]; DNA binding site
1311760002941	RNA-binding motif; other site
1311760002942	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1311760002943	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760002944	putative substrate translocation pore; other site
1311760002945	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1311760002946	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1311760002947	Putative exonuclease, RdgC; Region: RdgC; pfam04381
1311760002948	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1311760002949	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760002950	motif I; other site
1311760002951	active site
1311760002952	Protein of unknown function (DUF998); Region: DUF998; pfam06197
1311760002953	acetylornithine deacetylase; Provisional; Region: PRK05111
1311760002954	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1311760002955	metal binding site [ion binding]; metal-binding site
1311760002956	putative dimer interface [polypeptide binding]; other site
1311760002957	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1311760002958	outer membrane lipoprotein; Provisional; Region: PRK11023
1311760002959	BON domain; Region: BON; pfam04972
1311760002960	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1311760002961	dimer interface [polypeptide binding]; other site
1311760002962	active site
1311760002963	hypothetical protein; Reviewed; Region: PRK12497
1311760002964	LppC putative lipoprotein; Region: LppC; pfam04348
1311760002965	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1311760002966	putative ligand binding site [chemical binding]; other site
1311760002967	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1311760002968	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1311760002969	putative SAM binding site [chemical binding]; other site
1311760002970	putative homodimer interface [polypeptide binding]; other site
1311760002971	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760002972	putative substrate translocation pore; other site
1311760002973	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1311760002974	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1311760002975	Na binding site [ion binding]; other site
1311760002976	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1311760002977	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1311760002978	Bacterial transcriptional regulator; Region: IclR; pfam01614
1311760002979	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1311760002980	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1311760002981	Cell division protein ZapA; Region: ZapA; pfam05164
1311760002982	hypothetical protein; Reviewed; Region: PRK01736
1311760002983	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1311760002984	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1311760002985	substrate binding site [chemical binding]; other site
1311760002986	active site
1311760002987	Protein of unknown function (DUF416); Region: DUF416; cl01166
1311760002988	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1311760002989	IHF dimer interface [polypeptide binding]; other site
1311760002990	IHF - DNA interface [nucleotide binding]; other site
1311760002991	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1311760002992	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1311760002993	homodimer interface [polypeptide binding]; other site
1311760002994	oligonucleotide binding site [chemical binding]; other site
1311760002995	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1311760002996	Isochorismatase family; Region: Isochorismatase; pfam00857
1311760002997	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1311760002998	catalytic triad [active]
1311760002999	conserved cis-peptide bond; other site
1311760003000	Cupin; Region: Cupin_6; pfam12852
1311760003001	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760003002	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1311760003003	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760003004	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1311760003005	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1311760003006	intersubunit interface [polypeptide binding]; other site
1311760003007	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1311760003008	metal binding site [ion binding]; metal-binding site
1311760003009	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1311760003010	alkylphosphonate utilization operon protein PhnA; Region: phnA; TIGR00686
1311760003011	PhnA protein; Region: PhnA; pfam03831
1311760003012	ribonuclease R; Region: RNase_R; TIGR02063
1311760003013	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1311760003014	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1311760003015	RNB domain; Region: RNB; pfam00773
1311760003016	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1311760003017	RNA binding site [nucleotide binding]; other site
1311760003018	cell division protein MraZ; Reviewed; Region: PRK00326
1311760003019	MraZ protein; Region: MraZ; pfam02381
1311760003020	MraZ protein; Region: MraZ; pfam02381
1311760003021	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1311760003022	MraW methylase family; Region: Methyltransf_5; pfam01795
1311760003023	Cell division protein [Cell division and chromosome partitioning]; Region: FtsL; COG3116
1311760003024	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1311760003025	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1311760003026	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1311760003027	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1311760003028	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1311760003029	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760003030	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1311760003031	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1311760003032	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1311760003033	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760003034	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1311760003035	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1311760003036	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1311760003037	Mg++ binding site [ion binding]; other site
1311760003038	putative catalytic motif [active]
1311760003039	putative substrate binding site [chemical binding]; other site
1311760003040	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1311760003041	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760003042	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1311760003043	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1311760003044	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1311760003045	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1311760003046	active site
1311760003047	homodimer interface [polypeptide binding]; other site
1311760003048	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1311760003049	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1311760003050	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760003051	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1311760003052	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1311760003053	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1311760003054	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1311760003055	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1311760003056	Cell division protein FtsQ; Region: FtsQ; pfam03799
1311760003057	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1311760003058	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1311760003059	nucleotide binding site [chemical binding]; other site
1311760003060	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1311760003061	Cell division protein FtsA; Region: FtsA; pfam14450
1311760003062	cell division protein FtsZ; Validated; Region: PRK09330
1311760003063	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1311760003064	nucleotide binding site [chemical binding]; other site
1311760003065	SulA interaction site; other site
1311760003066	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1311760003067	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1311760003068	recombination and repair protein; Provisional; Region: PRK10869
1311760003069	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1311760003070	Walker A/P-loop; other site
1311760003071	ATP binding site [chemical binding]; other site
1311760003072	Q-loop/lid; other site
1311760003073	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1311760003074	ABC transporter signature motif; other site
1311760003075	Walker B; other site
1311760003076	D-loop; other site
1311760003077	H-loop/switch region; other site
1311760003078	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1311760003079	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1311760003080	HIGH motif; other site
1311760003081	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1311760003082	active site
1311760003083	KMSKS motif; other site
1311760003084	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1311760003085	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1311760003086	substrate binding pocket [chemical binding]; other site
1311760003087	membrane-bound complex binding site; other site
1311760003088	hinge residues; other site
1311760003089	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1311760003090	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1311760003091	catalytic residue [active]
1311760003092	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1311760003093	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1311760003094	dimerization interface [polypeptide binding]; other site
1311760003095	active site
1311760003096	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1311760003097	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1311760003098	DNA polymerase III subunit chi; Validated; Region: PRK05728
1311760003099	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1311760003100	Coenzyme A binding pocket [chemical binding]; other site
1311760003101	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
1311760003102	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1311760003103	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1311760003104	HIGH motif; other site
1311760003105	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1311760003106	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1311760003107	active site
1311760003108	KMSKS motif; other site
1311760003109	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1311760003110	tRNA binding surface [nucleotide binding]; other site
1311760003111	anticodon binding site; other site
1311760003112	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1311760003113	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
1311760003114	active site
1311760003115	catalytic triad [active]
1311760003116	oxyanion hole [active]
1311760003117	6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG0362
1311760003118	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1311760003119	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1311760003120	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
1311760003121	aspartate racemase; Region: asp_race; TIGR00035
1311760003122	ORF6N domain; Region: ORF6N; pfam10543
1311760003123	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1311760003124	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1311760003125	putative active site [active]
1311760003126	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1311760003127	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1311760003128	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1311760003129	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1311760003130	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1311760003131	active site
1311760003132	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1311760003133	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1311760003134	dimer interface [polypeptide binding]; other site
1311760003135	ADP-ribose binding site [chemical binding]; other site
1311760003136	active site
1311760003137	nudix motif; other site
1311760003138	metal binding site [ion binding]; metal-binding site
1311760003139	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760003140	RNA binding surface [nucleotide binding]; other site
1311760003141	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1311760003142	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1311760003143	dimerization interface [polypeptide binding]; other site
1311760003144	domain crossover interface; other site
1311760003145	redox-dependent activation switch; other site
1311760003146	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1311760003147	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1311760003148	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1311760003149	metal binding site [ion binding]; metal-binding site
1311760003150	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1311760003151	dimer interface [polypeptide binding]; other site
1311760003152	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1311760003153	metal binding site [ion binding]; metal-binding site
1311760003154	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1311760003155	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1311760003156	substrate binding site [chemical binding]; other site
1311760003157	glutamase interaction surface [polypeptide binding]; other site
1311760003158	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1311760003159	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1311760003160	catalytic residues [active]
1311760003161	BRO family, N-terminal domain; Region: Bro-N; smart01040
1311760003162	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1311760003163	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1311760003164	putative active site [active]
1311760003165	oxyanion strand; other site
1311760003166	catalytic triad [active]
1311760003167	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1311760003168	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760003169	active site
1311760003170	motif I; other site
1311760003171	motif II; other site
1311760003172	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1311760003173	putative active site pocket [active]
1311760003174	4-fold oligomerization interface [polypeptide binding]; other site
1311760003175	metal binding residues [ion binding]; metal-binding site
1311760003176	3-fold/trimer interface [polypeptide binding]; other site
1311760003177	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1311760003178	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1311760003179	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760003180	homodimer interface [polypeptide binding]; other site
1311760003181	catalytic residue [active]
1311760003182	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1311760003183	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760003184	Coenzyme A binding pocket [chemical binding]; other site
1311760003185	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1311760003186	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1311760003187	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1311760003188	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760003189	S-adenosylmethionine binding site [chemical binding]; other site
1311760003190	DNA polymerase III subunit psi; Validated; Region: PRK06856
1311760003191	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1311760003192	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760003193	Coenzyme A binding pocket [chemical binding]; other site
1311760003194	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1311760003195	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1311760003196	G1 box; other site
1311760003197	putative GEF interaction site [polypeptide binding]; other site
1311760003198	GTP/Mg2+ binding site [chemical binding]; other site
1311760003199	Switch I region; other site
1311760003200	G2 box; other site
1311760003201	G3 box; other site
1311760003202	Switch II region; other site
1311760003203	G4 box; other site
1311760003204	G5 box; other site
1311760003205	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1311760003206	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1311760003207	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1311760003208	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1311760003209	catalytic residue [active]
1311760003210	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1311760003211	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760003212	active site
1311760003213	motif I; other site
1311760003214	motif II; other site
1311760003215	Protein of unknown function (DUF497); Region: DUF497; pfam04365
1311760003216	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
1311760003217	Protein of unknown function (DUF3144); Region: DUF3144; pfam11342
1311760003218	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1311760003219	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760003220	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1311760003221	DNA binding residues [nucleotide binding]
1311760003222	integrase; Provisional; Region: PRK09692
1311760003223	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1311760003224	active site
1311760003225	Int/Topo IB signature motif; other site
1311760003226	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1311760003227	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1311760003228	probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684
1311760003229	Terminase small subunit; Region: Terminase_2; pfam03592
1311760003230	Autotransporter beta-domain; Region: Autotransporter; cl17461
1311760003231	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1311760003232	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1311760003233	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1311760003234	trimer interface [polypeptide binding]; other site
1311760003235	active site
1311760003236	substrate binding site [chemical binding]; other site
1311760003237	CoA binding site [chemical binding]; other site
1311760003238	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1311760003239	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1311760003240	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1311760003241	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1311760003242	SecA binding site; other site
1311760003243	Preprotein binding site; other site
1311760003244	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1311760003245	active site residue [active]
1311760003246	trigger factor; Provisional; Region: tig; PRK01490
1311760003247	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1311760003248	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1311760003249	elongation factor Tu; Reviewed; Region: PRK00049
1311760003250	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1311760003251	G1 box; other site
1311760003252	GEF interaction site [polypeptide binding]; other site
1311760003253	GTP/Mg2+ binding site [chemical binding]; other site
1311760003254	Switch I region; other site
1311760003255	G2 box; other site
1311760003256	G3 box; other site
1311760003257	Switch II region; other site
1311760003258	G4 box; other site
1311760003259	G5 box; other site
1311760003260	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1311760003261	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1311760003262	Antibiotic Binding Site [chemical binding]; other site
1311760003263	elongation factor G; Reviewed; Region: PRK00007
1311760003264	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1311760003265	G1 box; other site
1311760003266	putative GEF interaction site [polypeptide binding]; other site
1311760003267	GTP/Mg2+ binding site [chemical binding]; other site
1311760003268	Switch I region; other site
1311760003269	G2 box; other site
1311760003270	G3 box; other site
1311760003271	Switch II region; other site
1311760003272	G4 box; other site
1311760003273	G5 box; other site
1311760003274	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1311760003275	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1311760003276	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1311760003277	30S ribosomal protein S7; Validated; Region: PRK05302
1311760003278	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1311760003279	S17 interaction site [polypeptide binding]; other site
1311760003280	S8 interaction site; other site
1311760003281	16S rRNA interaction site [nucleotide binding]; other site
1311760003282	streptomycin interaction site [chemical binding]; other site
1311760003283	23S rRNA interaction site [nucleotide binding]; other site
1311760003284	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1311760003285	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760003286	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1311760003287	putative active site [active]
1311760003288	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760003289	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1311760003290	putative active site [active]
1311760003291	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; cl01604
1311760003292	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1311760003293	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1311760003294	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1311760003295	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1311760003296	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1311760003297	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760003298	ATP binding site [chemical binding]; other site
1311760003299	putative Mg++ binding site [ion binding]; other site
1311760003300	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1311760003301	nucleotide binding region [chemical binding]; other site
1311760003302	ATP-binding site [chemical binding]; other site
1311760003303	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1311760003304	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1311760003305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760003306	S-adenosylmethionine binding site [chemical binding]; other site
1311760003307	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1311760003308	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1311760003309	Divergent AAA domain; Region: AAA_4; pfam04326
1311760003310	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1311760003311	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760003312	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1311760003313	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760003314	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1311760003315	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1311760003316	active site
1311760003317	DNA binding site [nucleotide binding]
1311760003318	Int/Topo IB signature motif; other site
1311760003319	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760003320	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1311760003321	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760003322	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
1311760003323	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
1311760003324	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1311760003325	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1311760003326	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1311760003327	active pocket/dimerization site; other site
1311760003328	active site
1311760003329	phosphorylation site [posttranslational modification]
1311760003330	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1311760003331	active site
1311760003332	phosphorylation site [posttranslational modification]
1311760003333	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1311760003334	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
1311760003335	hypothetical protein; Provisional; Region: PRK02913
1311760003336	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1311760003337	triosephosphate isomerase; Provisional; Region: PRK14567
1311760003338	substrate binding site [chemical binding]; other site
1311760003339	dimer interface [polypeptide binding]; other site
1311760003340	catalytic triad [active]
1311760003341	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1311760003342	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1311760003343	Permutation of conserved domain; other site
1311760003344	active site
1311760003345	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1311760003346	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1311760003347	Predicted membrane protein [Function unknown]; Region: COG1238
1311760003348	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1311760003349	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1311760003350	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1311760003351	Peptidase family M23; Region: Peptidase_M23; pfam01551
1311760003352	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1311760003353	acyl carrier protein; Provisional; Region: acpP; PRK00982
1311760003354	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1311760003355	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1311760003356	substrate binding site [chemical binding]; other site
1311760003357	hexamer interface [polypeptide binding]; other site
1311760003358	metal binding site [ion binding]; metal-binding site
1311760003359	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1311760003360	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1311760003361	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1311760003362	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1311760003363	substrate binding pocket [chemical binding]; other site
1311760003364	membrane-bound complex binding site; other site
1311760003365	hinge residues; other site
1311760003366	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1311760003367	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760003368	dimer interface [polypeptide binding]; other site
1311760003369	conserved gate region; other site
1311760003370	putative PBP binding loops; other site
1311760003371	ABC-ATPase subunit interface; other site
1311760003372	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1311760003373	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1311760003374	Walker A/P-loop; other site
1311760003375	ATP binding site [chemical binding]; other site
1311760003376	Q-loop/lid; other site
1311760003377	ABC transporter signature motif; other site
1311760003378	Walker B; other site
1311760003379	D-loop; other site
1311760003380	H-loop/switch region; other site
1311760003381	YGGT family; Region: YGGT; pfam02325
1311760003382	YGGT family; Region: YGGT; pfam02325
1311760003383	hypothetical protein; Provisional; Region: PRK11702
1311760003384	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760003385	S-adenosylmethionine binding site [chemical binding]; other site
1311760003386	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1311760003387	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1311760003388	dimer interface [polypeptide binding]; other site
1311760003389	active site
1311760003390	CoA binding pocket [chemical binding]; other site
1311760003391	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1311760003392	dimer interface [polypeptide binding]; other site
1311760003393	allosteric magnesium binding site [ion binding]; other site
1311760003394	active site
1311760003395	aspartate-rich active site metal binding site; other site
1311760003396	Schiff base residues; other site
1311760003397	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
1311760003398	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1311760003399	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1311760003400	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1311760003401	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1311760003402	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1311760003403	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1311760003404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1311760003405	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1311760003406	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1311760003407	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760003408	S-adenosylmethionine binding site [chemical binding]; other site
1311760003409	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1311760003410	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1311760003411	Cl binding site [ion binding]; other site
1311760003412	oligomer interface [polypeptide binding]; other site
1311760003413	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1311760003414	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1311760003415	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1311760003416	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1311760003417	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1311760003418	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1311760003419	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1311760003420	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1311760003421	substrate binding site [chemical binding]; other site
1311760003422	oxyanion hole (OAH) forming residues; other site
1311760003423	trimer interface [polypeptide binding]; other site
1311760003424	penicillin-binding protein 1B; Region: PBP_1b; TIGR02071
1311760003425	Transglycosylase; Region: Transgly; pfam00912
1311760003426	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1311760003427	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1311760003428	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1311760003429	dimerization interface [polypeptide binding]; other site
1311760003430	DPS ferroxidase diiron center [ion binding]; other site
1311760003431	ion pore; other site
1311760003432	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1311760003433	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760003434	S-adenosylmethionine binding site [chemical binding]; other site
1311760003435	ornithine carbamoyltransferase; Provisional; Region: PRK01713
1311760003436	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1311760003437	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1311760003438	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1311760003439	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1311760003440	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1311760003441	Predicted membrane protein [Function unknown]; Region: COG2259
1311760003442	DNA utilization protein GntX; Provisional; Region: PRK11595
1311760003443	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760003444	active site
1311760003445	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760003446	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1311760003447	active site
1311760003448	motif I; other site
1311760003449	motif II; other site
1311760003450	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760003451	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1311760003452	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1311760003453	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1311760003454	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1311760003455	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1311760003456	substrate binding pocket [chemical binding]; other site
1311760003457	chain length determination region; other site
1311760003458	substrate-Mg2+ binding site; other site
1311760003459	catalytic residues [active]
1311760003460	aspartate-rich region 1; other site
1311760003461	active site lid residues [active]
1311760003462	aspartate-rich region 2; other site
1311760003463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1311760003464	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1311760003465	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1311760003466	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1311760003467	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1311760003468	NAD(P) binding site [chemical binding]; other site
1311760003469	homotetramer interface [polypeptide binding]; other site
1311760003470	homodimer interface [polypeptide binding]; other site
1311760003471	active site
1311760003472	Branched-chain amino acid permeases [Amino acid transport and metabolism]; Region: BrnQ; COG1114
1311760003473	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1311760003474	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1311760003475	DNA binding site [nucleotide binding]
1311760003476	catalytic residue [active]
1311760003477	H2TH interface [polypeptide binding]; other site
1311760003478	putative catalytic residues [active]
1311760003479	turnover-facilitating residue; other site
1311760003480	intercalation triad [nucleotide binding]; other site
1311760003481	8OG recognition residue [nucleotide binding]; other site
1311760003482	putative reading head residues; other site
1311760003483	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1311760003484	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1311760003485	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1311760003486	putative active site [active]
1311760003487	dimerization interface [polypeptide binding]; other site
1311760003488	putative tRNAtyr binding site [nucleotide binding]; other site
1311760003489	hypothetical protein; Reviewed; Region: PRK01637
1311760003490	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1311760003491	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1311760003492	putative catalytic cysteine [active]
1311760003493	DNA mismatch repair protein MutL; Region: mutl; TIGR00585
1311760003494	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760003495	ATP binding site [chemical binding]; other site
1311760003496	Mg2+ binding site [ion binding]; other site
1311760003497	G-X-G motif; other site
1311760003498	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1311760003499	ATP binding site [chemical binding]; other site
1311760003500	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1311760003501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1311760003502	RelB antitoxin; Region: RelB; cl01171
1311760003503	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1311760003504	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1311760003505	bacterial Hfq-like; Region: Hfq; cd01716
1311760003506	hexamer interface [polypeptide binding]; other site
1311760003507	Sm1 motif; other site
1311760003508	RNA binding site [nucleotide binding]; other site
1311760003509	Sm2 motif; other site
1311760003510	GTPase HflX; Provisional; Region: PRK11058
1311760003511	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1311760003512	HflX GTPase family; Region: HflX; cd01878
1311760003513	G1 box; other site
1311760003514	GTP/Mg2+ binding site [chemical binding]; other site
1311760003515	Switch I region; other site
1311760003516	G2 box; other site
1311760003517	G3 box; other site
1311760003518	Switch II region; other site
1311760003519	G4 box; other site
1311760003520	G5 box; other site
1311760003521	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1311760003522	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760003523	trimer interface [polypeptide binding]; other site
1311760003524	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760003525	trimer interface [polypeptide binding]; other site
1311760003526	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760003527	trimer interface [polypeptide binding]; other site
1311760003528	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1311760003529	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1311760003530	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1311760003531	YadA-like C-terminal region; Region: YadA; pfam03895
1311760003532	Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571
1311760003533	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
1311760003534	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1311760003535	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1311760003536	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1311760003537	nucleotide binding site [chemical binding]; other site
1311760003538	chaperone protein DnaJ; Provisional; Region: PRK10767
1311760003539	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1311760003540	HSP70 interaction site [polypeptide binding]; other site
1311760003541	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1311760003542	substrate binding site [polypeptide binding]; other site
1311760003543	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1311760003544	Zn binding sites [ion binding]; other site
1311760003545	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1311760003546	dimer interface [polypeptide binding]; other site
1311760003547	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1311760003548	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1311760003549	tetramer interface [polypeptide binding]; other site
1311760003550	heme binding pocket [chemical binding]; other site
1311760003551	NADPH binding site [chemical binding]; other site
1311760003552	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1311760003553	CPxP  motif; other site
1311760003554	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1311760003555	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1311760003556	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1311760003557	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1311760003558	metal binding site [ion binding]; metal-binding site
1311760003559	dimer interface [polypeptide binding]; other site
1311760003560	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1311760003561	ArsC family; Region: ArsC; pfam03960
1311760003562	putative catalytic residues [active]
1311760003563	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1311760003564	dihydropteroate synthase; Region: DHPS; TIGR01496
1311760003565	substrate binding pocket [chemical binding]; other site
1311760003566	dimer interface [polypeptide binding]; other site
1311760003567	inhibitor binding site; inhibition site
1311760003568	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1311760003569	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760003570	RNA binding surface [nucleotide binding]; other site
1311760003571	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1311760003572	active site
1311760003573	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1311760003574	Conserved TM helix; Region: TM_helix; pfam05552
1311760003575	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1311760003576	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1311760003577	Patatin-like phospholipase; Region: Patatin; pfam01734
1311760003578	active site
1311760003579	nucleophile elbow; other site
1311760003580	Predicted flavoprotein [General function prediction only]; Region: COG0431
1311760003581	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1311760003582	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1311760003583	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760003584	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1311760003585	dimerization interface [polypeptide binding]; other site
1311760003586	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1311760003587	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1311760003588	active site
1311760003589	FMN binding site [chemical binding]; other site
1311760003590	substrate binding site [chemical binding]; other site
1311760003591	homotetramer interface [polypeptide binding]; other site
1311760003592	catalytic residue [active]
1311760003593	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1311760003594	dimer interface [polypeptide binding]; other site
1311760003595	FMN binding site [chemical binding]; other site
1311760003596	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1311760003597	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1311760003598	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR2; cd08268
1311760003599	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1311760003600	putative NAD(P) binding site [chemical binding]; other site
1311760003601	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1311760003602	luciferase-type oxidoreductase, BA3436 family; Region: lucif_BA3436; TIGR03571
1311760003603	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1311760003604	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1311760003605	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1311760003606	putative NAD(P) binding site [chemical binding]; other site
1311760003607	putative substrate binding site [chemical binding]; other site
1311760003608	catalytic Zn binding site [ion binding]; other site
1311760003609	structural Zn binding site [ion binding]; other site
1311760003610	dimer interface [polypeptide binding]; other site
1311760003611	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1311760003612	S-formylglutathione hydrolase; Region: PLN02442
1311760003613	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1311760003614	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1311760003615	phosphate binding site [ion binding]; other site
1311760003616	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1311760003617	putative active site [active]
1311760003618	Ap4A binding site [chemical binding]; other site
1311760003619	nudix motif; other site
1311760003620	putative metal binding site [ion binding]; other site
1311760003621	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1311760003622	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1311760003623	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1311760003624	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1311760003625	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760003626	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760003627	motif II; other site
1311760003628	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1311760003629	PemK-like protein; Region: PemK; pfam02452
1311760003630	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1311760003631	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1311760003632	active site
1311760003633	HIGH motif; other site
1311760003634	dimer interface [polypeptide binding]; other site
1311760003635	KMSKS motif; other site
1311760003636	Peptidase family M48; Region: Peptidase_M48; pfam01435
1311760003637	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1311760003638	dimer interface [polypeptide binding]; other site
1311760003639	substrate binding site [chemical binding]; other site
1311760003640	metal binding sites [ion binding]; metal-binding site
1311760003641	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1311760003642	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1311760003643	dimerization interface [polypeptide binding]; other site
1311760003644	thymidylate kinase; Validated; Region: tmk; PRK00698
1311760003645	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1311760003646	TMP-binding site; other site
1311760003647	ATP-binding site [chemical binding]; other site
1311760003648	DNA polymerase III subunit delta'; Validated; Region: PRK06871
1311760003649	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1311760003650	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1311760003651	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1311760003652	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1311760003653	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1311760003654	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1311760003655	active site
1311760003656	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
1311760003657	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1311760003658	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1311760003659	putative active site [active]
1311760003660	putative metal binding site [ion binding]; other site
1311760003661	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1311760003662	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1311760003663	DNA-binding site [nucleotide binding]; DNA binding site
1311760003664	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1311760003665	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760003666	homodimer interface [polypeptide binding]; other site
1311760003667	catalytic residue [active]
1311760003668	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1311760003669	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1311760003670	active site
1311760003671	multimer interface [polypeptide binding]; other site
1311760003672	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1311760003673	predicted active site [active]
1311760003674	catalytic triad [active]
1311760003675	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1311760003676	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1311760003677	putative metal binding site [ion binding]; other site
1311760003678	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1311760003679	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1311760003680	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1311760003681	active site
1311760003682	HIGH motif; other site
1311760003683	KMSK motif region; other site
1311760003684	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1311760003685	tRNA binding surface [nucleotide binding]; other site
1311760003686	anticodon binding site; other site
1311760003687	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1311760003688	GTP1/OBG; Region: GTP1_OBG; pfam01018
1311760003689	Obg GTPase; Region: Obg; cd01898
1311760003690	G1 box; other site
1311760003691	GTP/Mg2+ binding site [chemical binding]; other site
1311760003692	Switch I region; other site
1311760003693	G2 box; other site
1311760003694	G3 box; other site
1311760003695	Switch II region; other site
1311760003696	G4 box; other site
1311760003697	G5 box; other site
1311760003698	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49); Region: G6PD_bact; pfam10786
1311760003699	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1311760003700	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1311760003701	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1311760003702	heme exporter protein CcmC; Region: ccmC; TIGR01191
1311760003703	heme exporter protein CcmB; Region: ccmB; TIGR01190
1311760003704	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1311760003705	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1311760003706	Walker A/P-loop; other site
1311760003707	ATP binding site [chemical binding]; other site
1311760003708	Q-loop/lid; other site
1311760003709	ABC transporter signature motif; other site
1311760003710	Walker B; other site
1311760003711	D-loop; other site
1311760003712	H-loop/switch region; other site
1311760003713	DNA replication initiation factor; Validated; Region: PRK06893
1311760003714	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1311760003715	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760003716	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1311760003717	peptide binding site [polypeptide binding]; other site
1311760003718	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1311760003719	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760003720	dimer interface [polypeptide binding]; other site
1311760003721	conserved gate region; other site
1311760003722	putative PBP binding loops; other site
1311760003723	ABC-ATPase subunit interface; other site
1311760003724	dipeptide transporter; Provisional; Region: PRK10913
1311760003725	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1311760003726	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760003727	dimer interface [polypeptide binding]; other site
1311760003728	conserved gate region; other site
1311760003729	putative PBP binding loops; other site
1311760003730	ABC-ATPase subunit interface; other site
1311760003731	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1311760003732	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760003733	Walker A/P-loop; other site
1311760003734	ATP binding site [chemical binding]; other site
1311760003735	Q-loop/lid; other site
1311760003736	ABC transporter signature motif; other site
1311760003737	Walker B; other site
1311760003738	D-loop; other site
1311760003739	H-loop/switch region; other site
1311760003740	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1311760003741	RNA polymerase sigma factor; Provisional; Region: PRK12530
1311760003742	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760003743	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1311760003744	DNA binding residues [nucleotide binding]
1311760003745	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1311760003746	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
1311760003747	Integrase core domain; Region: rve_3; pfam13683
1311760003748	Integrase core domain; Region: rve; pfam00665
1311760003749	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760003750	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760003751	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760003752	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1311760003753	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1311760003754	WzyE protein; Region: WzyE; cl11643
1311760003755	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1311760003756	glutamine synthetase; Provisional; Region: glnA; PRK09469
1311760003757	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1311760003758	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1311760003759	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1311760003760	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760003761	Coenzyme A binding pocket [chemical binding]; other site
1311760003762	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1311760003763	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1311760003764	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1311760003765	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1311760003766	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
1311760003767	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1311760003768	Mg++ binding site [ion binding]; other site
1311760003769	putative catalytic motif [active]
1311760003770	substrate binding site [chemical binding]; other site
1311760003771	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1311760003772	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1311760003773	inhibitor-cofactor binding pocket; inhibition site
1311760003774	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760003775	catalytic residue [active]
1311760003776	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1311760003777	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1311760003778	putative active site [active]
1311760003779	putative NTP binding site [chemical binding]; other site
1311760003780	putative nucleic acid binding site [nucleotide binding]; other site
1311760003781	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1311760003782	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1311760003783	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1311760003784	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1311760003785	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1311760003786	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1311760003787	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1311760003788	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1311760003789	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1311760003790	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1311760003791	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1311760003792	DNA binding site [nucleotide binding]
1311760003793	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1311760003794	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1311760003795	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1311760003796	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1311760003797	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1311760003798	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1311760003799	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1311760003800	RPB1 interaction site [polypeptide binding]; other site
1311760003801	RPB11 interaction site [polypeptide binding]; other site
1311760003802	RPB10 interaction site [polypeptide binding]; other site
1311760003803	RPB3 interaction site [polypeptide binding]; other site
1311760003804	DsrH like protein; Region: DsrH; cl17347
1311760003805	sulfur relay protein TusC/DsrF; Region: sulf_tusC_dsrF; TIGR03010
1311760003806	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1311760003807	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1311760003808	YheO-like PAS domain; Region: PAS_6; pfam08348
1311760003809	HTH domain; Region: HTH_22; pfam13309
1311760003810	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1311760003811	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1311760003812	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1311760003813	SlyX; Region: SlyX; cl01090
1311760003814	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1311760003815	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1311760003816	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1311760003817	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1311760003818	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760003819	FeS/SAM binding site; other site
1311760003820	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1311760003821	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1311760003822	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760003823	FeS/SAM binding site; other site
1311760003824	glycine radical enzyme, YjjI family; Region: glycyl_YjjI; TIGR04040
1311760003825	Pyruvate formate lyase; Region: PFL; pfam02901
1311760003826	Pleckstrin homology-like domain; Region: PH-like; cl17171
1311760003827	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1311760003828	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1311760003829	core dimer interface [polypeptide binding]; other site
1311760003830	peripheral dimer interface [polypeptide binding]; other site
1311760003831	L10 interface [polypeptide binding]; other site
1311760003832	L11 interface [polypeptide binding]; other site
1311760003833	putative EF-Tu interaction site [polypeptide binding]; other site
1311760003834	putative EF-G interaction site [polypeptide binding]; other site
1311760003835	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1311760003836	23S rRNA interface [nucleotide binding]; other site
1311760003837	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1311760003838	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK06816
1311760003839	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1311760003840	dimer interface [polypeptide binding]; other site
1311760003841	active site
1311760003842	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
1311760003843	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1311760003844	dimer interface [polypeptide binding]; other site
1311760003845	active site
1311760003846	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760003847	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
1311760003848	NAD(P) binding site [chemical binding]; other site
1311760003849	active site
1311760003850	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1311760003851	Divergent AAA domain; Region: AAA_4; pfam04326
1311760003852	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1311760003853	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
1311760003854	putative active site 1 [active]
1311760003855	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1311760003856	mRNA/rRNA interface [nucleotide binding]; other site
1311760003857	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1311760003858	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1311760003859	23S rRNA interface [nucleotide binding]; other site
1311760003860	L7/L12 interface [polypeptide binding]; other site
1311760003861	putative thiostrepton binding site; other site
1311760003862	L25 interface [polypeptide binding]; other site
1311760003863	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1311760003864	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1311760003865	putative homodimer interface [polypeptide binding]; other site
1311760003866	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1311760003867	heterodimer interface [polypeptide binding]; other site
1311760003868	homodimer interface [polypeptide binding]; other site
1311760003869	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1311760003870	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1311760003871	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760003872	DNA binding site [nucleotide binding]
1311760003873	domain linker motif; other site
1311760003874	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1311760003875	putative ligand binding site [chemical binding]; other site
1311760003876	putative dimerization interface [polypeptide binding]; other site
1311760003877	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1311760003878	active site
1311760003879	P-loop; other site
1311760003880	phosphorylation site [posttranslational modification]
1311760003881	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1311760003882	DNA protecting protein DprA; Region: dprA; TIGR00732
1311760003883	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1311760003884	active site
1311760003885	catalytic residues [active]
1311760003886	metal binding site [ion binding]; metal-binding site
1311760003887	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1311760003888	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1311760003889	NADP binding site [chemical binding]; other site
1311760003890	homopentamer interface [polypeptide binding]; other site
1311760003891	substrate binding site [chemical binding]; other site
1311760003892	active site
1311760003893	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1311760003894	active site 1 [active]
1311760003895	dimer interface [polypeptide binding]; other site
1311760003896	active site 2 [active]
1311760003897	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1311760003898	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1311760003899	Organiser of macrodomain of Terminus of chromosome; Region: MatP; pfam06303
1311760003900	outer membrane protein A; Reviewed; Region: PRK10808
1311760003901	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1311760003902	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1311760003903	ligand binding site [chemical binding]; other site
1311760003904	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1311760003905	FAD binding domain; Region: FAD_binding_4; pfam01565
1311760003906	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1311760003907	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1311760003908	CoenzymeA binding site [chemical binding]; other site
1311760003909	subunit interaction site [polypeptide binding]; other site
1311760003910	PHB binding site; other site
1311760003911	membrane protein insertase; Provisional; Region: PRK01318
1311760003912	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1311760003913	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1311760003914	dimer interface [polypeptide binding]; other site
1311760003915	catalytic triad [active]
1311760003916	peroxidatic and resolving cysteines [active]
1311760003917	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1311760003918	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1311760003919	putative acyl-acceptor binding pocket; other site
1311760003920	FtsI repressor; Provisional; Region: PRK10883
1311760003921	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1311760003922	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1311760003923	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1311760003924	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1311760003925	pyridoxamine kinase; Validated; Region: PRK05756
1311760003926	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1311760003927	dimer interface [polypeptide binding]; other site
1311760003928	pyridoxal binding site [chemical binding]; other site
1311760003929	ATP binding site [chemical binding]; other site
1311760003930	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1311760003931	Peptidase S8 family domain in Autotransporter serine proteases; Region: Peptidases_S8_Autotransporter_serine_protease_like; cd04848
1311760003932	catalytic triad [active]
1311760003933	putative active site [active]
1311760003934	autotransporter-associated beta strand repeat; Region: autotrns_rpt; TIGR02601
1311760003935	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1311760003936	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1311760003937	intersubunit interface [polypeptide binding]; other site
1311760003938	active site
1311760003939	Zn2+ binding site [ion binding]; other site
1311760003940	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1311760003941	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1311760003942	AP (apurinic/apyrimidinic) site pocket; other site
1311760003943	DNA interaction; other site
1311760003944	Metal-binding active site; metal-binding site
1311760003945	transcriptional repressor UlaR; Provisional; Region: PRK13509
1311760003946	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1311760003947	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760003948	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1311760003949	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1311760003950	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1311760003951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1311760003952	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1311760003953	active site
1311760003954	P-loop; other site
1311760003955	phosphorylation site [posttranslational modification]
1311760003956	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1311760003957	active site
1311760003958	phosphorylation site [posttranslational modification]
1311760003959	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1311760003960	active site
1311760003961	dimer interface [polypeptide binding]; other site
1311760003962	magnesium binding site [ion binding]; other site
1311760003963	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1311760003964	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1311760003965	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1311760003966	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1311760003967	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1311760003968	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1311760003969	Domain of unknown function DUF302; Region: DUF302; cl01364
1311760003970	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
1311760003971	Putative esterase; Region: Esterase; pfam00756
1311760003972	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1311760003973	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
1311760003974	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1311760003975	Flavodoxin; Region: Flavodoxin_1; pfam00258
1311760003976	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1311760003977	FAD binding pocket [chemical binding]; other site
1311760003978	conserved FAD binding motif [chemical binding]; other site
1311760003979	phosphate binding motif [ion binding]; other site
1311760003980	beta-alpha-beta structure motif; other site
1311760003981	NAD binding pocket [chemical binding]; other site
1311760003982	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1311760003983	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1311760003984	23S rRNA interface [nucleotide binding]; other site
1311760003985	putative translocon interaction site; other site
1311760003986	signal recognition particle (SRP54) interaction site; other site
1311760003987	L23 interface [polypeptide binding]; other site
1311760003988	trigger factor interaction site; other site
1311760003989	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1311760003990	23S rRNA interface [nucleotide binding]; other site
1311760003991	5S rRNA interface [nucleotide binding]; other site
1311760003992	putative antibiotic binding site [chemical binding]; other site
1311760003993	L25 interface [polypeptide binding]; other site
1311760003994	L27 interface [polypeptide binding]; other site
1311760003995	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1311760003996	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1311760003997	G-X-X-G motif; other site
1311760003998	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1311760003999	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1311760004000	protein-rRNA interface [nucleotide binding]; other site
1311760004001	putative translocon binding site; other site
1311760004002	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1311760004003	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1311760004004	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1311760004005	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1311760004006	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1311760004007	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1311760004008	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1311760004009	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1311760004010	TfoX N-terminal domain; Region: TfoX_N; cl17592
1311760004011	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1311760004012	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1311760004013	Class II fumarases; Region: Fumarase_classII; cd01362
1311760004014	active site
1311760004015	tetramer interface [polypeptide binding]; other site
1311760004016	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; pfam13627
1311760004017	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1311760004018	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1311760004019	active site
1311760004020	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1311760004021	substrate binding site [chemical binding]; other site
1311760004022	catalytic residues [active]
1311760004023	dimer interface [polypeptide binding]; other site
1311760004024	glutathionine S-transferase; Provisional; Region: PRK10542
1311760004025	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1311760004026	C-terminal domain interface [polypeptide binding]; other site
1311760004027	GSH binding site (G-site) [chemical binding]; other site
1311760004028	dimer interface [polypeptide binding]; other site
1311760004029	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1311760004030	dimer interface [polypeptide binding]; other site
1311760004031	N-terminal domain interface [polypeptide binding]; other site
1311760004032	substrate binding pocket (H-site) [chemical binding]; other site
1311760004033	protease TldD; Provisional; Region: tldD; PRK10735
1311760004034	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1311760004035	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1311760004036	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1311760004037	Iron-sulfur protein interface; other site
1311760004038	proximal quinone binding site [chemical binding]; other site
1311760004039	C-subunit interface; other site
1311760004040	distal quinone binding site; other site
1311760004041	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1311760004042	D-subunit interface [polypeptide binding]; other site
1311760004043	Iron-sulfur protein interface; other site
1311760004044	proximal quinone binding site [chemical binding]; other site
1311760004045	distal quinone binding site [chemical binding]; other site
1311760004046	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1311760004047	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1311760004048	catalytic loop [active]
1311760004049	iron binding site [ion binding]; other site
1311760004050	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1311760004051	L-aspartate oxidase; Provisional; Region: PRK06175
1311760004052	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1311760004053	poxB regulator PoxA; Provisional; Region: PRK09350
1311760004054	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1311760004055	motif 1; other site
1311760004056	dimer interface [polypeptide binding]; other site
1311760004057	active site
1311760004058	motif 2; other site
1311760004059	motif 3; other site
1311760004060	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1311760004061	EamA-like transporter family; Region: EamA; pfam00892
1311760004062	BCCT family transporter; Region: BCCT; pfam02028
1311760004063	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1311760004064	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1311760004065	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1311760004066	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1311760004067	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
1311760004068	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1311760004069	Flavodoxin domain; Region: Flavodoxin_5; cl17428
1311760004070	Cation transport protein; Region: TrkH; cl17365
1311760004071	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1311760004072	hypothetical protein; Provisional; Region: PRK11568
1311760004073	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1311760004074	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1311760004075	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1311760004076	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1311760004077	putative active site [active]
1311760004078	substrate binding site [chemical binding]; other site
1311760004079	putative cosubstrate binding site; other site
1311760004080	catalytic site [active]
1311760004081	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1311760004082	substrate binding site [chemical binding]; other site
1311760004083	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1311760004084	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760004085	Walker A/P-loop; other site
1311760004086	ATP binding site [chemical binding]; other site
1311760004087	Q-loop/lid; other site
1311760004088	ABC transporter signature motif; other site
1311760004089	Walker B; other site
1311760004090	D-loop; other site
1311760004091	H-loop/switch region; other site
1311760004092	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760004093	Walker A/P-loop; other site
1311760004094	ATP binding site [chemical binding]; other site
1311760004095	Q-loop/lid; other site
1311760004096	ABC transporter signature motif; other site
1311760004097	Walker B; other site
1311760004098	D-loop; other site
1311760004099	H-loop/switch region; other site
1311760004100	Protein of unknown function, DUF479; Region: DUF479; cl01203
1311760004101	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1311760004102	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760004103	ABC-ATPase subunit  interface; other site
1311760004104	dimer interface [polypeptide binding]; other site
1311760004105	putative PBP binding regions; other site
1311760004106	Integrase core domain; Region: rve; pfam00665
1311760004107	Integrase core domain; Region: rve_3; pfam13683
1311760004108	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1311760004109	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1311760004110	intersubunit interface [polypeptide binding]; other site
1311760004111	lipoyl synthase; Provisional; Region: PRK05481
1311760004112	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760004113	FeS/SAM binding site; other site
1311760004114	lipoate-protein ligase B; Provisional; Region: PRK14342
1311760004115	hypothetical protein; Provisional; Region: PRK04998
1311760004116	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1311760004117	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1311760004118	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1311760004119	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1311760004120	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1311760004121	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1311760004122	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1311760004123	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1311760004124	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1311760004125	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1311760004126	Oligomerisation domain; Region: Oligomerisation; cl00519
1311760004127	EamA-like transporter family; Region: EamA; cl17759
1311760004128	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1311760004129	EamA-like transporter family; Region: EamA; pfam00892
1311760004130	mannonate dehydratase; Provisional; Region: PRK03906
1311760004131	mannonate dehydratase; Region: uxuA; TIGR00695
1311760004132	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1311760004133	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1311760004134	DNA-binding site [nucleotide binding]; DNA binding site
1311760004135	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1311760004136	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1311760004137	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1311760004138	putative NAD(P) binding site [chemical binding]; other site
1311760004139	catalytic Zn binding site [ion binding]; other site
1311760004140	structural Zn binding site [ion binding]; other site
1311760004141	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1311760004142	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1311760004143	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1311760004144	DctM-like transporters; Region: DctM; pfam06808
1311760004145	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1311760004146	D-mannonate oxidoreductase; Provisional; Region: PRK08277
1311760004147	putative D-mannonate oxidoreductase, classical (c) SDR; Region: mannonate_red_SDR_c; cd08935
1311760004148	putative NAD(P) binding site [chemical binding]; other site
1311760004149	active site
1311760004150	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1311760004151	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1311760004152	substrate binding site [chemical binding]; other site
1311760004153	ATP binding site [chemical binding]; other site
1311760004154	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1311760004155	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1311760004156	active site
1311760004157	intersubunit interface [polypeptide binding]; other site
1311760004158	catalytic residue [active]
1311760004159	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1311760004160	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1311760004161	MutS domain I; Region: MutS_I; pfam01624
1311760004162	MutS domain II; Region: MutS_II; pfam05188
1311760004163	MutS domain III; Region: MutS_III; pfam05192
1311760004164	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1311760004165	Walker A/P-loop; other site
1311760004166	ATP binding site [chemical binding]; other site
1311760004167	Q-loop/lid; other site
1311760004168	ABC transporter signature motif; other site
1311760004169	Walker B; other site
1311760004170	D-loop; other site
1311760004171	H-loop/switch region; other site
1311760004172	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1311760004173	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1311760004174	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1311760004175	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1311760004176	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1311760004177	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1311760004178	catalytic residues [active]
1311760004179	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760004180	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760004181	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1311760004182	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1311760004183	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1311760004184	G1 box; other site
1311760004185	GTP/Mg2+ binding site [chemical binding]; other site
1311760004186	Switch I region; other site
1311760004187	G2 box; other site
1311760004188	Switch II region; other site
1311760004189	G3 box; other site
1311760004190	G4 box; other site
1311760004191	G5 box; other site
1311760004192	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1311760004193	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1311760004194	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1311760004195	Ligand Binding Site [chemical binding]; other site
1311760004196	TilS substrate binding domain; Region: TilS; pfam09179
1311760004197	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1311760004198	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1311760004199	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1311760004200	active site
1311760004201	Int/Topo IB signature motif; other site
1311760004202	glutamate racemase; Provisional; Region: PRK00865
1311760004203	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1311760004204	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1311760004205	Chorismate lyase; Region: Chor_lyase; cl01230
1311760004206	uridine phosphorylase; Provisional; Region: PRK11178
1311760004207	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1311760004208	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760004209	motif II; other site
1311760004210	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1311760004211	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1311760004212	active site
1311760004213	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1311760004214	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1311760004215	dimer interface [polypeptide binding]; other site
1311760004216	motif 1; other site
1311760004217	active site
1311760004218	motif 2; other site
1311760004219	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1311760004220	putative deacylase active site [active]
1311760004221	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1311760004222	active site
1311760004223	motif 3; other site
1311760004224	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1311760004225	anticodon binding site; other site
1311760004226	heat shock protein 90; Provisional; Region: PRK05218
1311760004227	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760004228	ATP binding site [chemical binding]; other site
1311760004229	Mg2+ binding site [ion binding]; other site
1311760004230	G-X-G motif; other site
1311760004231	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1311760004232	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1311760004233	oligomeric interface; other site
1311760004234	putative active site [active]
1311760004235	homodimer interface [polypeptide binding]; other site
1311760004236	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1311760004237	Pathogenicity locus; Region: Cdd1; pfam11731
1311760004238	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1311760004239	generic binding surface II; other site
1311760004240	ssDNA binding site; other site
1311760004241	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760004242	ATP binding site [chemical binding]; other site
1311760004243	putative Mg++ binding site [ion binding]; other site
1311760004244	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760004245	nucleotide binding region [chemical binding]; other site
1311760004246	ATP-binding site [chemical binding]; other site
1311760004247	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1311760004248	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1311760004249	active site
1311760004250	substrate binding site [chemical binding]; other site
1311760004251	metal binding site [ion binding]; metal-binding site
1311760004252	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1311760004253	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1311760004254	P-loop; other site
1311760004255	Magnesium ion binding site [ion binding]; other site
1311760004256	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1311760004257	Magnesium ion binding site [ion binding]; other site
1311760004258	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
1311760004259	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
1311760004260	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
1311760004261	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1311760004262	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1311760004263	active site
1311760004264	homodimer interface [polypeptide binding]; other site
1311760004265	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1311760004266	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1311760004267	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1311760004268	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1311760004269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4641
1311760004270	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1311760004271	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1311760004272	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1311760004273	active site
1311760004274	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1311760004275	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1311760004276	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4641
1311760004277	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1311760004278	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1311760004279	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1311760004280	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
1311760004281	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1311760004282	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1311760004283	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1311760004284	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1311760004285	Walker A/P-loop; other site
1311760004286	ATP binding site [chemical binding]; other site
1311760004287	Q-loop/lid; other site
1311760004288	ABC transporter signature motif; other site
1311760004289	Walker B; other site
1311760004290	D-loop; other site
1311760004291	H-loop/switch region; other site
1311760004292	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1311760004293	putative metal binding site [ion binding]; other site
1311760004294	hypothetical protein; Provisional; Region: PRK01752
1311760004295	SEC-C motif; Region: SEC-C; pfam02810
1311760004296	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1311760004297	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1311760004298	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1311760004299	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1311760004300	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1311760004301	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760004302	S-adenosylmethionine binding site [chemical binding]; other site
1311760004303	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1311760004304	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1311760004305	active site
1311760004306	catalytic tetrad [active]
1311760004307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760004308	putative substrate translocation pore; other site
1311760004309	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1311760004310	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1311760004311	active site
1311760004312	catalytic site [active]
1311760004313	metal binding site [ion binding]; metal-binding site
1311760004314	glycerol-3-phosphate transporter; Region: glpT; TIGR00712
1311760004315	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760004316	putative substrate translocation pore; other site
1311760004317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760004318	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1311760004319	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
1311760004320	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1311760004321	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1311760004322	putative N- and C-terminal domain interface [polypeptide binding]; other site
1311760004323	putative active site [active]
1311760004324	MgATP binding site [chemical binding]; other site
1311760004325	catalytic site [active]
1311760004326	metal binding site [ion binding]; metal-binding site
1311760004327	putative xylulose binding site [chemical binding]; other site
1311760004328	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1311760004329	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1311760004330	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1311760004331	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760004332	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760004333	TM-ABC transporter signature motif; other site
1311760004334	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1311760004335	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760004336	Walker A/P-loop; other site
1311760004337	ATP binding site [chemical binding]; other site
1311760004338	Q-loop/lid; other site
1311760004339	ABC transporter signature motif; other site
1311760004340	Walker B; other site
1311760004341	D-loop; other site
1311760004342	H-loop/switch region; other site
1311760004343	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760004344	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1311760004345	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1311760004346	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1311760004347	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1311760004348	DctM-like transporters; Region: DctM; pfam06808
1311760004349	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
1311760004350	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1311760004351	Domain of unknown function (DUF386); Region: DUF386; cl01047
1311760004352	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1311760004353	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1311760004354	substrate binding site [chemical binding]; other site
1311760004355	Mn binding site [ion binding]; other site
1311760004356	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1311760004357	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1311760004358	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1311760004359	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1311760004360	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1311760004361	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1311760004362	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1311760004363	IMP binding site; other site
1311760004364	dimer interface [polypeptide binding]; other site
1311760004365	interdomain contacts; other site
1311760004366	partial ornithine binding site; other site
1311760004367	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1311760004368	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1311760004369	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1311760004370	catalytic site [active]
1311760004371	subunit interface [polypeptide binding]; other site
1311760004372	F0F1 ATP synthase subunit I; Validated; Region: PRK06099
1311760004373	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1311760004374	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1311760004375	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1311760004376	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1311760004377	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1311760004378	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1311760004379	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1311760004380	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1311760004381	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1311760004382	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1311760004383	beta subunit interaction interface [polypeptide binding]; other site
1311760004384	Walker A motif; other site
1311760004385	ATP binding site [chemical binding]; other site
1311760004386	Walker B motif; other site
1311760004387	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1311760004388	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1311760004389	core domain interface [polypeptide binding]; other site
1311760004390	delta subunit interface [polypeptide binding]; other site
1311760004391	epsilon subunit interface [polypeptide binding]; other site
1311760004392	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1311760004393	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1311760004394	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1311760004395	alpha subunit interaction interface [polypeptide binding]; other site
1311760004396	Walker A motif; other site
1311760004397	ATP binding site [chemical binding]; other site
1311760004398	Walker B motif; other site
1311760004399	inhibitor binding site; inhibition site
1311760004400	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1311760004401	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1311760004402	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1311760004403	gamma subunit interface [polypeptide binding]; other site
1311760004404	epsilon subunit interface [polypeptide binding]; other site
1311760004405	LBP interface [polypeptide binding]; other site
1311760004406	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1311760004407	dimer interface [polypeptide binding]; other site
1311760004408	active site
1311760004409	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1311760004410	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1311760004411	dimerization interface [polypeptide binding]; other site
1311760004412	putative DNA binding site [nucleotide binding]; other site
1311760004413	putative Zn2+ binding site [ion binding]; other site
1311760004414	AsnC family; Region: AsnC_trans_reg; pfam01037
1311760004415	FMN-binding protein MioC; Provisional; Region: PRK09004
1311760004416	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760004417	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1311760004418	peptide binding site [polypeptide binding]; other site
1311760004419	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1311760004420	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1311760004421	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1311760004422	Phage tail tube protein; Region: Tail_tube; pfam10618
1311760004423	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
1311760004424	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760004425	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1311760004426	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760004427	sequence-specific DNA binding site [nucleotide binding]; other site
1311760004428	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760004429	salt bridge; other site
1311760004430	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760004431	Catalytic site [active]
1311760004432	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1311760004433	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1311760004434	inhibitor site; inhibition site
1311760004435	active site
1311760004436	dimer interface [polypeptide binding]; other site
1311760004437	catalytic residue [active]
1311760004438	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1311760004439	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1311760004440	nucleotide binding site [chemical binding]; other site
1311760004441	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1311760004442	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1311760004443	putative active site cavity [active]
1311760004444	selenocysteine synthase; Provisional; Region: PRK04311
1311760004445	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1311760004446	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1311760004447	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1311760004448	catalytic residue [active]
1311760004449	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1311760004450	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1311760004451	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1311760004452	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1311760004453	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1311760004454	G1 box; other site
1311760004455	putative GEF interaction site [polypeptide binding]; other site
1311760004456	GTP/Mg2+ binding site [chemical binding]; other site
1311760004457	Switch I region; other site
1311760004458	G2 box; other site
1311760004459	G3 box; other site
1311760004460	Switch II region; other site
1311760004461	G4 box; other site
1311760004462	G5 box; other site
1311760004463	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1311760004464	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1311760004465	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1311760004466	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1311760004467	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1311760004468	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
1311760004469	TRAP-type uncharacterized transport system, fused permease components [General function prediction only]; Region: COG4666
1311760004470	DctM-like transporters; Region: DctM; pfam06808
1311760004471	TRAP-type uncharacterized transport system, fused permease components [General function prediction only]; Region: COG4666
1311760004472	Domain of unknown function (DUF3394); Region: DUF3394; pfam11874
1311760004473	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1311760004474	Ligand Binding Site [chemical binding]; other site
1311760004475	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1311760004476	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
1311760004477	putative RNA binding site [nucleotide binding]; other site
1311760004478	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760004479	S-adenosylmethionine binding site [chemical binding]; other site
1311760004480	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1311760004481	TrkA-N domain; Region: TrkA_N; pfam02254
1311760004482	TrkA-C domain; Region: TrkA_C; pfam02080
1311760004483	TrkA-N domain; Region: TrkA_N; pfam02254
1311760004484	TrkA-C domain; Region: TrkA_C; pfam02080
1311760004485	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1311760004486	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1311760004487	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1311760004488	NAD binding site [chemical binding]; other site
1311760004489	catalytic residues [active]
1311760004490	substrate binding site [chemical binding]; other site
1311760004491	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1311760004492	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1311760004493	dimer interface [polypeptide binding]; other site
1311760004494	active site
1311760004495	metal binding site [ion binding]; metal-binding site
1311760004496	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1311760004497	active site turn [active]
1311760004498	phosphorylation site [posttranslational modification]
1311760004499	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1311760004500	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
1311760004501	putative ligand binding site [chemical binding]; other site
1311760004502	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760004503	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760004504	TM-ABC transporter signature motif; other site
1311760004505	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1311760004506	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760004507	Walker A/P-loop; other site
1311760004508	ATP binding site [chemical binding]; other site
1311760004509	Q-loop/lid; other site
1311760004510	ABC transporter signature motif; other site
1311760004511	Walker B; other site
1311760004512	D-loop; other site
1311760004513	H-loop/switch region; other site
1311760004514	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760004515	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1311760004516	intersubunit interface [polypeptide binding]; other site
1311760004517	active site
1311760004518	Zn2+ binding site [ion binding]; other site
1311760004519	Fucose dissimilation pathway protein FucU [Carbohydrate transport and metabolism]; Region: FucU; COG4154
1311760004520	L-fuculokinase; Provisional; Region: PRK10331
1311760004521	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1311760004522	nucleotide binding site [chemical binding]; other site
1311760004523	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1311760004524	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1311760004525	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1311760004526	trimer interface [polypeptide binding]; other site
1311760004527	substrate binding site [chemical binding]; other site
1311760004528	Mn binding site [ion binding]; other site
1311760004529	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1311760004530	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1311760004531	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760004532	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1311760004533	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1311760004534	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1311760004535	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1311760004536	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1311760004537	dimerization interface [polypeptide binding]; other site
1311760004538	ATP binding site [chemical binding]; other site
1311760004539	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1311760004540	dimerization interface [polypeptide binding]; other site
1311760004541	ATP binding site [chemical binding]; other site
1311760004542	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1311760004543	putative active site [active]
1311760004544	catalytic triad [active]
1311760004545	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1311760004546	Transposase IS200 like; Region: Y1_Tnp; cl00848
1311760004547	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
1311760004548	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
1311760004549	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760004550	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760004551	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1311760004552	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1311760004553	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1311760004554	Moco binding site; other site
1311760004555	metal coordination site [ion binding]; other site
1311760004556	RNA polymerase sigma-70 factor, TIGR02943 family; Region: Sig70_famx1
1311760004557	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760004558	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1311760004559	DNA binding residues [nucleotide binding]
1311760004560	putative oxidoreductase; Provisional; Region: PRK11579
1311760004561	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1311760004562	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1311760004563	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1311760004564	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1311760004565	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1311760004566	metal-binding site [ion binding]
1311760004567	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1311760004568	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1311760004569	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1311760004570	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1311760004571	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
1311760004572	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1311760004573	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760004574	NAD(P) binding site [chemical binding]; other site
1311760004575	active site
1311760004576	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1311760004577	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1311760004578	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760004579	motif II; other site
1311760004580	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1311760004581	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1311760004582	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760004583	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1311760004584	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1311760004585	putative active site [active]
1311760004586	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1311760004587	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1311760004588	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1311760004589	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1311760004590	active site
1311760004591	P-loop; other site
1311760004592	phosphorylation site [posttranslational modification]
1311760004593	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1311760004594	active site
1311760004595	phosphorylation site [posttranslational modification]
1311760004596	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1311760004597	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1311760004598	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1311760004599	Mannitol repressor; Region: MtlR; cl11450
1311760004600	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1311760004601	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1311760004602	transmembrane helices; other site
1311760004603	TrkA-C domain; Region: TrkA_C; pfam02080
1311760004604	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1311760004605	TrkA-C domain; Region: TrkA_C; pfam02080
1311760004606	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1311760004607	transcriptional repressor DicA; Reviewed; Region: PRK09706
1311760004608	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760004609	non-specific DNA binding site [nucleotide binding]; other site
1311760004610	salt bridge; other site
1311760004611	sequence-specific DNA binding site [nucleotide binding]; other site
1311760004612	Predicted transcriptional regulator [Transcription]; Region: Nlp; COG3423
1311760004613	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760004614	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760004615	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760004616	TM-ABC transporter signature motif; other site
1311760004617	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1311760004618	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760004619	Walker A/P-loop; other site
1311760004620	ATP binding site [chemical binding]; other site
1311760004621	Q-loop/lid; other site
1311760004622	ABC transporter signature motif; other site
1311760004623	Walker B; other site
1311760004624	D-loop; other site
1311760004625	H-loop/switch region; other site
1311760004626	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760004627	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1311760004628	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1311760004629	putative ligand binding site [chemical binding]; other site
1311760004630	xylose isomerase; Provisional; Region: PRK05474
1311760004631	xylose isomerase; Region: xylose_isom_A; TIGR02630
1311760004632	xylulokinase; Provisional; Region: PRK15027
1311760004633	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1311760004634	N- and C-terminal domain interface [polypeptide binding]; other site
1311760004635	active site
1311760004636	MgATP binding site [chemical binding]; other site
1311760004637	catalytic site [active]
1311760004638	metal binding site [ion binding]; metal-binding site
1311760004639	xylulose binding site [chemical binding]; other site
1311760004640	homodimer interface [polypeptide binding]; other site
1311760004641	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1311760004642	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
1311760004643	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1311760004644	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1311760004645	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1311760004646	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1311760004647	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1311760004648	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1311760004649	CrcB-like protein; Region: CRCB; cl09114
1311760004650	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1311760004651	amphipathic channel; other site
1311760004652	Asn-Pro-Ala signature motifs; other site
1311760004653	glycerol kinase; Provisional; Region: glpK; PRK00047
1311760004654	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1311760004655	N- and C-terminal domain interface [polypeptide binding]; other site
1311760004656	active site
1311760004657	MgATP binding site [chemical binding]; other site
1311760004658	catalytic site [active]
1311760004659	metal binding site [ion binding]; metal-binding site
1311760004660	glycerol binding site [chemical binding]; other site
1311760004661	homotetramer interface [polypeptide binding]; other site
1311760004662	homodimer interface [polypeptide binding]; other site
1311760004663	FBP binding site [chemical binding]; other site
1311760004664	protein IIAGlc interface [polypeptide binding]; other site
1311760004665	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1311760004666	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1311760004667	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1311760004668	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1311760004669	active site
1311760004670	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1311760004671	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760004672	dimer interface [polypeptide binding]; other site
1311760004673	conserved gate region; other site
1311760004674	putative PBP binding loops; other site
1311760004675	ABC-ATPase subunit interface; other site
1311760004676	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1311760004677	NMT1-like family; Region: NMT1_2; pfam13379
1311760004678	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1311760004679	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1311760004680	HlyD family secretion protein; Region: HlyD_3; pfam13437
1311760004681	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
1311760004682	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
1311760004683	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1311760004684	ATP-binding cassette domain of hemolysin B, subfamily C; Region: ABCC_Hemolysin; cd03252
1311760004685	Walker A/P-loop; other site
1311760004686	ATP binding site [chemical binding]; other site
1311760004687	Q-loop/lid; other site
1311760004688	ABC transporter signature motif; other site
1311760004689	Walker B; other site
1311760004690	D-loop; other site
1311760004691	H-loop/switch region; other site
1311760004692	RTX N-terminal domain; Region: RTX; pfam02382
1311760004693	RTX C-terminal domain; Region: RTX_C; pfam08339
1311760004694	RTX toxin acyltransferase family; Region: HlyC; pfam02794
1311760004695	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
1311760004696	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1311760004697	substrate binding pocket [chemical binding]; other site
1311760004698	membrane-bound complex binding site; other site
1311760004699	hinge residues; other site
1311760004700	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1311760004701	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1311760004702	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760004703	Walker A motif; other site
1311760004704	ATP binding site [chemical binding]; other site
1311760004705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760004706	Walker B motif; other site
1311760004707	arginine finger; other site
1311760004708	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1311760004709	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1311760004710	active site
1311760004711	HslU subunit interaction site [polypeptide binding]; other site
1311760004712	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1311760004713	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1311760004714	EamA-like transporter family; Region: EamA; pfam00892
1311760004715	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1311760004716	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1311760004717	putative metal binding site [ion binding]; other site
1311760004718	adenine DNA glycosylase; Provisional; Region: PRK10880
1311760004719	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1311760004720	minor groove reading motif; other site
1311760004721	helix-hairpin-helix signature motif; other site
1311760004722	substrate binding pocket [chemical binding]; other site
1311760004723	active site
1311760004724	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1311760004725	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1311760004726	DNA binding and oxoG recognition site [nucleotide binding]
1311760004727	oxidative damage protection protein; Provisional; Region: PRK05408
1311760004728	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1311760004729	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1311760004730	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1311760004731	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1311760004732	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1311760004733	catalytic residue [active]
1311760004734	signal recognition particle protein; Provisional; Region: PRK10867
1311760004735	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1311760004736	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1311760004737	P loop; other site
1311760004738	GTP binding site [chemical binding]; other site
1311760004739	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1311760004740	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1311760004741	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1311760004742	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760004743	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1311760004744	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1311760004745	putative aldolase; Validated; Region: PRK08130
1311760004746	intersubunit interface [polypeptide binding]; other site
1311760004747	active site
1311760004748	Zn2+ binding site [ion binding]; other site
1311760004749	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
1311760004750	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1311760004751	Metal-binding active site; metal-binding site
1311760004752	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1311760004753	GntP family permease; Region: GntP_permease; pfam02447
1311760004754	Predicted peptidase [General function prediction only]; Region: COG4099
1311760004755	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1311760004756	putative heme utilization radical SAM enzyme HutW; Region: rSAM_HutW; TIGR04107
1311760004757	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760004758	FeS/SAM binding site; other site
1311760004759	putative heme utilization carrier protein HutX; Region: HutX; TIGR04108
1311760004760	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760004761	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1311760004762	NAD(P) binding site [chemical binding]; other site
1311760004763	active site
1311760004764	Dihaem cytochrome c; Region: DHC; pfam09626
1311760004765	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1311760004766	dimer interface [polypeptide binding]; other site
1311760004767	motif 1; other site
1311760004768	active site
1311760004769	motif 2; other site
1311760004770	motif 3; other site
1311760004771	Glutaredoxin-related protein [Posttranslational modification, protein turnover, chaperones]; Region: COG4545
1311760004772	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1311760004773	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1311760004774	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1311760004775	DALR anticodon binding domain; Region: DALR_1; pfam05746
1311760004776	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1311760004777	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1311760004778	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1311760004779	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1311760004780	YheO-like PAS domain; Region: PAS_6; pfam08348
1311760004781	HTH domain; Region: HTH_22; pfam13309
1311760004782	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1311760004783	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1311760004784	active site
1311760004785	Int/Topo IB signature motif; other site
1311760004786	Protein of unknown function (DUF454); Region: DUF454; cl01063
1311760004787	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1311760004788	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760004789	S-adenosylmethionine binding site [chemical binding]; other site
1311760004790	hypothetical protein; Provisional; Region: PRK11027
1311760004791	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1311760004792	Uncharacterized conserved protein [Function unknown]; Region: COG2938
1311760004793	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1311760004794	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1311760004795	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1311760004796	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1311760004797	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1311760004798	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1311760004799	MPT binding site; other site
1311760004800	trimer interface [polypeptide binding]; other site
1311760004801	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1311760004802	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
1311760004803	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760004804	binding surface
1311760004805	TPR motif; other site
1311760004806	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
1311760004807	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
1311760004808	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1311760004809	catalytic residues [active]
1311760004810	central insert; other site
1311760004811	pantothenate kinase; Provisional; Region: PRK05439
1311760004812	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1311760004813	ATP-binding site [chemical binding]; other site
1311760004814	CoA-binding site [chemical binding]; other site
1311760004815	Mg2+-binding site [ion binding]; other site
1311760004816	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1311760004817	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1311760004818	Antibiotic Binding Site [chemical binding]; other site
1311760004819	TOBE domain; Region: TOBE_2; pfam08402
1311760004820	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760004821	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760004822	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760004823	Catalytic site [active]
1311760004824	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1311760004825	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760004826	Integrase core domain; Region: rve; pfam00665
1311760004827	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1311760004828	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
1311760004829	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760004830	DNA binding site [nucleotide binding]
1311760004831	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
1311760004832	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
1311760004833	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760004834	non-specific DNA binding site [nucleotide binding]; other site
1311760004835	salt bridge; other site
1311760004836	sequence-specific DNA binding site [nucleotide binding]; other site
1311760004837	Mor transcription activator family; Region: Mor; cl02360
1311760004838	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1311760004839	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1311760004840	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1311760004841	Protein of unknown function (DUF2644); Region: DUF2644; pfam10841
1311760004842	Protein of unknown function (DUF2681); Region: DUF2681; pfam10883
1311760004843	Protein of unknown function (DUF1804); Region: DUF1804; pfam08822
1311760004844	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
1311760004845	Protein of unknown function (DUF935); Region: DUF935; pfam06074
1311760004846	Mu-like prophage protein gp29 [Function unknown]; Region: COG4383
1311760004847	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
1311760004848	Mu-like prophage protein gpG [General function prediction only]; Region: COG5005
1311760004849	Mu-like prophage I protein; Region: Mu-like_Pro; pfam10123
1311760004850	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; pfam10124
1311760004851	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
1311760004852	Domain of unknown function (DUF1834); Region: DUF1834; pfam08873
1311760004853	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
1311760004854	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
1311760004855	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1311760004856	Phage tail tube protein; Region: Tail_tube; pfam10618
1311760004857	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1311760004858	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
1311760004859	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
1311760004860	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
1311760004861	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1311760004862	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; cl15410
1311760004863	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1311760004864	Phage protein GP46; Region: GP46; cl01814
1311760004865	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1311760004866	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1311760004867	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1311760004868	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
1311760004869	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1311760004870	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1311760004871	Walker A/P-loop; other site
1311760004872	ATP binding site [chemical binding]; other site
1311760004873	Q-loop/lid; other site
1311760004874	ABC transporter signature motif; other site
1311760004875	Walker B; other site
1311760004876	D-loop; other site
1311760004877	H-loop/switch region; other site
1311760004878	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1311760004879	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760004880	dimer interface [polypeptide binding]; other site
1311760004881	conserved gate region; other site
1311760004882	putative PBP binding loops; other site
1311760004883	ABC-ATPase subunit interface; other site
1311760004884	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760004885	dimer interface [polypeptide binding]; other site
1311760004886	conserved gate region; other site
1311760004887	putative PBP binding loops; other site
1311760004888	ABC-ATPase subunit interface; other site
1311760004889	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1311760004890	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1311760004891	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1311760004892	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1311760004893	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760004894	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1311760004895	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1311760004896	glutaminase active site [active]
1311760004897	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1311760004898	dimer interface [polypeptide binding]; other site
1311760004899	active site
1311760004900	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1311760004901	dimer interface [polypeptide binding]; other site
1311760004902	active site
1311760004903	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1311760004904	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1311760004905	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1311760004906	RNA binding site [nucleotide binding]; other site
1311760004907	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1311760004908	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1311760004909	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1311760004910	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1311760004911	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1311760004912	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1311760004913	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1311760004914	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1311760004915	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1311760004916	23S rRNA interface [nucleotide binding]; other site
1311760004917	L21e interface [polypeptide binding]; other site
1311760004918	5S rRNA interface [nucleotide binding]; other site
1311760004919	L27 interface [polypeptide binding]; other site
1311760004920	L5 interface [polypeptide binding]; other site
1311760004921	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1311760004922	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1311760004923	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1311760004924	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1311760004925	23S rRNA binding site [nucleotide binding]; other site
1311760004926	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1311760004927	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1311760004928	SecY translocase; Region: SecY; pfam00344
1311760004929	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1311760004930	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1311760004931	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1311760004932	30S ribosomal protein S11; Validated; Region: PRK05309
1311760004933	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1311760004934	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1311760004935	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760004936	RNA binding surface [nucleotide binding]; other site
1311760004937	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1311760004938	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1311760004939	alphaNTD homodimer interface [polypeptide binding]; other site
1311760004940	alphaNTD - beta interaction site [polypeptide binding]; other site
1311760004941	alphaNTD - beta' interaction site [polypeptide binding]; other site
1311760004942	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1311760004943	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1311760004944	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1311760004945	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1311760004946	putative dimerization interface [polypeptide binding]; other site
1311760004947	putative ligand binding site [chemical binding]; other site
1311760004948	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760004949	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1311760004950	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760004951	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1311760004952	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1311760004953	putative ligand binding site [chemical binding]; other site
1311760004954	putative dimerization interface [polypeptide binding]; other site
1311760004955	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1311760004956	Shikimate kinase; Region: SKI; pfam01202
1311760004957	ATP-binding site [chemical binding]; other site
1311760004958	Gluconate-6-phosphate binding site [chemical binding]; other site
1311760004959	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1311760004960	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1311760004961	cell density-dependent motility repressor; Provisional; Region: PRK10082
1311760004962	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760004963	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1311760004964	dimerization interface [polypeptide binding]; other site
1311760004965	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1311760004966	aspartate racemase; Region: asp_race; TIGR00035
1311760004967	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1311760004968	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1311760004969	succinic semialdehyde dehydrogenase; Region: PLN02278
1311760004970	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1311760004971	tetramerization interface [polypeptide binding]; other site
1311760004972	NAD(P) binding site [chemical binding]; other site
1311760004973	catalytic residues [active]
1311760004974	KduI/IolB family; Region: KduI; cl01508
1311760004975	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1311760004976	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1311760004977	tetrameric interface [polypeptide binding]; other site
1311760004978	NAD binding site [chemical binding]; other site
1311760004979	catalytic residues [active]
1311760004980	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1311760004981	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1311760004982	ligand binding site [chemical binding]; other site
1311760004983	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1311760004984	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760004985	Walker A/P-loop; other site
1311760004986	ATP binding site [chemical binding]; other site
1311760004987	Q-loop/lid; other site
1311760004988	ABC transporter signature motif; other site
1311760004989	Walker B; other site
1311760004990	D-loop; other site
1311760004991	H-loop/switch region; other site
1311760004992	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760004993	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760004994	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760004995	TM-ABC transporter signature motif; other site
1311760004996	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1311760004997	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1311760004998	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1311760004999	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1311760005000	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1311760005001	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1311760005002	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1311760005003	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1311760005004	Metal-binding active site; metal-binding site
1311760005005	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1311760005006	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1311760005007	PYR/PP interface [polypeptide binding]; other site
1311760005008	dimer interface [polypeptide binding]; other site
1311760005009	TPP binding site [chemical binding]; other site
1311760005010	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1311760005011	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1311760005012	TPP-binding site; other site
1311760005013	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1311760005014	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1311760005015	substrate binding site [chemical binding]; other site
1311760005016	ATP binding site [chemical binding]; other site
1311760005017	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1311760005018	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1311760005019	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
1311760005020	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1311760005021	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1311760005022	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1311760005023	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1311760005024	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1311760005025	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1311760005026	putative active site [active]
1311760005027	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1311760005028	active site turn [active]
1311760005029	phosphorylation site [posttranslational modification]
1311760005030	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1311760005031	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1311760005032	RimM N-terminal domain; Region: RimM; pfam01782
1311760005033	PRC-barrel domain; Region: PRC; pfam05239
1311760005034	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1311760005035	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1311760005036	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cd11523
1311760005037	metal binding site [ion binding]; metal-binding site
1311760005038	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1311760005039	Cupin domain; Region: Cupin_2; cl17218
1311760005040	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1311760005041	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1311760005042	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1311760005043	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1311760005044	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1311760005045	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1311760005046	carboxyltransferase (CT) interaction site; other site
1311760005047	biotinylation site [posttranslational modification]; other site
1311760005048	Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane]; Region: OCH1; COG3774
1311760005049	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
1311760005050	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1311760005051	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1311760005052	active site
1311760005053	trimer interface [polypeptide binding]; other site
1311760005054	dimer interface [polypeptide binding]; other site
1311760005055	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1311760005056	Coenzyme A binding pocket [chemical binding]; other site
1311760005057	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1311760005058	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1311760005059	trimer interface [polypeptide binding]; other site
1311760005060	active site
1311760005061	substrate binding site [chemical binding]; other site
1311760005062	CoA binding site [chemical binding]; other site
1311760005063	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1311760005064	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1311760005065	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1311760005066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760005067	S-adenosylmethionine binding site [chemical binding]; other site
1311760005068	Sporulation related domain; Region: SPOR; pfam05036
1311760005069	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1311760005070	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1311760005071	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1311760005072	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760005073	Walker A motif; other site
1311760005074	ATP binding site [chemical binding]; other site
1311760005075	Part of AAA domain; Region: AAA_19; pfam13245
1311760005076	Family description; Region: UvrD_C_2; pfam13538
1311760005077	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760005078	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1311760005079	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1311760005080	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760005081	S-adenosylmethionine binding site [chemical binding]; other site
1311760005082	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1311760005083	non-specific DNA binding site [nucleotide binding]; other site
1311760005084	salt bridge; other site
1311760005085	sequence-specific DNA binding site [nucleotide binding]; other site
1311760005086	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1311760005087	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1311760005088	catalytic residues [active]
1311760005089	catalytic nucleophile [active]
1311760005090	Recombinase; Region: Recombinase; pfam07508
1311760005091	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1311760005092	ParB-like nuclease domain; Region: ParB; smart00470
1311760005093	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1311760005094	ParB-like nuclease domain; Region: ParBc; cl02129
1311760005095	RepB plasmid partitioning protein; Region: RepB; pfam07506
1311760005096	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760005097	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760005098	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760005099	Integrase core domain; Region: rve; pfam00665
1311760005100	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760005101	Integrase core domain; Region: rve_3; pfam13683
1311760005102	TniQ; Region: TniQ; pfam06527
1311760005103	Bacterial TniB protein; Region: TniB; pfam05621
1311760005104	AAA domain; Region: AAA_22; pfam13401
1311760005105	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760005106	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760005107	Integrase core domain; Region: rve; pfam00665
1311760005108	Integrase core domain; Region: rve_3; cl15866
1311760005109	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1311760005110	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
1311760005111	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
1311760005112	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1311760005113	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1311760005114	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1311760005115	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1311760005116	Putative serine esterase (DUF676); Region: DUF676; pfam05057
1311760005117	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1311760005118	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1311760005119	dimer interface [polypeptide binding]; other site
1311760005120	tetramer interface [polypeptide binding]; other site
1311760005121	PYR/PP interface [polypeptide binding]; other site
1311760005122	TPP binding site [chemical binding]; other site
1311760005123	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1311760005124	TPP-binding site; other site
1311760005125	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1311760005126	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1311760005127	Ligand binding site; other site
1311760005128	metal-binding site
1311760005129	Protein of unknown function (DUF406); Region: DUF406; pfam04175
1311760005130	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1311760005131	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1311760005132	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1311760005133	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1311760005134	ligand binding site [chemical binding]; other site
1311760005135	calcium binding site [ion binding]; other site
1311760005136	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1311760005137	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1311760005138	ligand binding site [chemical binding]; other site
1311760005139	calcium binding site [ion binding]; other site
1311760005140	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760005141	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1311760005142	Walker A/P-loop; other site
1311760005143	ATP binding site [chemical binding]; other site
1311760005144	Q-loop/lid; other site
1311760005145	ABC transporter signature motif; other site
1311760005146	Walker B; other site
1311760005147	D-loop; other site
1311760005148	H-loop/switch region; other site
1311760005149	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760005150	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760005151	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760005152	TM-ABC transporter signature motif; other site
1311760005153	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760005154	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1311760005155	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760005156	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760005157	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11905
1311760005158	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1311760005159	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1311760005160	Glutamate binding site [chemical binding]; other site
1311760005161	NAD binding site [chemical binding]; other site
1311760005162	catalytic residues [active]
1311760005163	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1311760005164	ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073
1311760005165	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1311760005166	inhibitor-cofactor binding pocket; inhibition site
1311760005167	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760005168	catalytic residue [active]
1311760005169	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3676
1311760005170	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760005171	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1311760005172	Plastocyanin [Energy production and conversion]; Region: PetE; COG3794
1311760005173	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
1311760005174	hypothetical protein; Provisional; Region: PRK10506
1311760005175	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
1311760005176	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1311760005177	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
1311760005178	protease3; Provisional; Region: PRK15101
1311760005179	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1311760005180	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1311760005181	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1311760005182	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760005183	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1311760005184	peptide binding site [polypeptide binding]; other site
1311760005185	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1311760005186	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1311760005187	N-terminal plug; other site
1311760005188	ligand-binding site [chemical binding]; other site
1311760005189	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1311760005190	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1311760005191	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1311760005192	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
1311760005193	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1311760005194	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1311760005195	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1311760005196	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1311760005197	FAD binding domain; Region: FAD_binding_4; pfam01565
1311760005198	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1311760005199	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1311760005200	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1311760005201	ligand binding site [chemical binding]; other site
1311760005202	flexible hinge region; other site
1311760005203	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1311760005204	putative switch regulator; other site
1311760005205	non-specific DNA interactions [nucleotide binding]; other site
1311760005206	DNA binding site [nucleotide binding]
1311760005207	sequence specific DNA binding site [nucleotide binding]; other site
1311760005208	putative cAMP binding site [chemical binding]; other site
1311760005209	hypothetical protein; Provisional; Region: PRK04966
1311760005210	division inhibitor protein; Provisional; Region: slmA; PRK09480
1311760005211	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1311760005212	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1311760005213	trimer interface [polypeptide binding]; other site
1311760005214	active site
1311760005215	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1311760005216	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1311760005217	Ligand binding site; other site
1311760005218	metal-binding site
1311760005219	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1311760005220	Src Homology 3 domain superfamily; Region: SH3; cl17036
1311760005221	peptide ligand binding site [polypeptide binding]; other site
1311760005222	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1311760005223	Flavoprotein; Region: Flavoprotein; pfam02441
1311760005224	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1311760005225	hypothetical protein; Reviewed; Region: PRK00024
1311760005226	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1311760005227	MPN+ (JAMM) motif; other site
1311760005228	Zinc-binding site [ion binding]; other site
1311760005229	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1311760005230	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1311760005231	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1311760005232	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1311760005233	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1311760005234	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1311760005235	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1311760005236	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1311760005237	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1311760005238	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
1311760005239	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1311760005240	inhibitor-cofactor binding pocket; inhibition site
1311760005241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760005242	catalytic residue [active]
1311760005243	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1311760005244	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760005245	catalytic residue [active]
1311760005246	Bacterial OB fold (BOF) protein; Region: BOF; cl01196
1311760005247	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1311760005248	ferredoxin-type protein NapF; Region: napF; TIGR00402
1311760005249	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1311760005250	4Fe-4S binding domain; Region: Fer4; cl02805
1311760005251	NapD protein; Region: NapD; pfam03927
1311760005252	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1311760005253	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1311760005254	[4Fe-4S] binding site [ion binding]; other site
1311760005255	molybdopterin cofactor binding site; other site
1311760005256	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1311760005257	molybdopterin cofactor binding site; other site
1311760005258	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1311760005259	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1311760005260	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1311760005261	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1311760005262	Nitrate reductase cytochrome c-type subunit (NapB); Region: NapB; pfam03892
1311760005263	periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; Region: napC_nirT; TIGR02161
1311760005264	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
1311760005265	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1311760005266	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1311760005267	active site
1311760005268	metal binding site [ion binding]; metal-binding site
1311760005269	hexamer interface [polypeptide binding]; other site
1311760005270	Periplasmic nitrate reductase protein NapE; Region: NapE; cl01848
1311760005271	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
1311760005272	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1311760005273	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1311760005274	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1311760005275	molybdopterin cofactor binding site [chemical binding]; other site
1311760005276	substrate binding site [chemical binding]; other site
1311760005277	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1311760005278	molybdopterin cofactor binding site; other site
1311760005279	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1311760005280	Lipoprotein GNA1870 C terminal like; Region: Lipoprot_C; pfam08794
1311760005281	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1311760005282	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760005283	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760005284	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760005285	Integrase core domain; Region: rve; pfam00665
1311760005286	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760005287	Integrase core domain; Region: rve_3; pfam13683
1311760005288	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1311760005289	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1311760005290	dimer interface [polypeptide binding]; other site
1311760005291	ADP-ribose binding site [chemical binding]; other site
1311760005292	active site
1311760005293	nudix motif; other site
1311760005294	metal binding site [ion binding]; metal-binding site
1311760005295	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1311760005296	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1311760005297	Predicted membrane protein [Function unknown]; Region: COG2510
1311760005298	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1311760005299	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09560
1311760005300	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1311760005301	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1311760005302	Na binding site [ion binding]; other site
1311760005303	Protein of unknown function (DUF997); Region: DUF997; pfam06196
1311760005304	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1311760005305	dimerization interface [polypeptide binding]; other site
1311760005306	DNA binding site [nucleotide binding]
1311760005307	corepressor binding sites; other site
1311760005308	VacJ like lipoprotein; Region: VacJ; cl01073
1311760005309	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1311760005310	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1311760005311	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1311760005312	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1311760005313	Virulence protein [General function prediction only]; Region: COG3943
1311760005314	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1311760005315	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1311760005316	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1311760005317	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1311760005318	trimer interface [polypeptide binding]; other site
1311760005319	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1311760005320	trimer interface [polypeptide binding]; other site
1311760005321	Haemagglutinin; Region: HIM; pfam05662
1311760005322	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1311760005323	YadA-like C-terminal region; Region: YadA; pfam03895
1311760005324	Domain of unknown function (DUF4298); Region: DUF4298; pfam14131
1311760005325	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1311760005326	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1311760005327	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1311760005328	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760005329	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1311760005330	dimerization interface [polypeptide binding]; other site
1311760005331	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
1311760005332	catalytic triad [active]
1311760005333	dimer interface [polypeptide binding]; other site
1311760005334	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1311760005335	threonine synthase; Validated; Region: PRK09225
1311760005336	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1311760005337	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1311760005338	catalytic residue [active]
1311760005339	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1311760005340	active site
1311760005341	dimer interfaces [polypeptide binding]; other site
1311760005342	catalytic residues [active]
1311760005343	TIGR01666 family membrane protein; Region: YCCS
1311760005344	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1311760005345	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1311760005346	HEXXH motif domain; Region: mod_HExxH; TIGR04267
1311760005347	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1311760005348	Paraquat-inducible protein A; Region: PqiA; pfam04403
1311760005349	Paraquat-inducible protein A; Region: PqiA; pfam04403
1311760005350	ketol-acid reductoisomerase; Validated; Region: PRK05225
1311760005351	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1311760005352	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1311760005353	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1311760005354	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1311760005355	ATP binding site [chemical binding]; other site
1311760005356	active site
1311760005357	substrate binding site [chemical binding]; other site
1311760005358	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1311760005359	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1311760005360	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1311760005361	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1311760005362	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1311760005363	NAD binding site [chemical binding]; other site
1311760005364	dimerization interface [polypeptide binding]; other site
1311760005365	product binding site; other site
1311760005366	substrate binding site [chemical binding]; other site
1311760005367	zinc binding site [ion binding]; other site
1311760005368	catalytic residues [active]
1311760005369	putative phosphate acyltransferase; Provisional; Region: PRK05331
1311760005370	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1311760005371	hypothetical protein; Provisional; Region: PRK11193
1311760005372	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1311760005373	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
1311760005374	Domain of unknown function DUF21; Region: DUF21; pfam01595
1311760005375	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1311760005376	Transporter associated domain; Region: CorC_HlyC; smart01091
1311760005377	uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334
1311760005378	Na2 binding site [ion binding]; other site
1311760005379	putative substrate binding site 1 [chemical binding]; other site
1311760005380	Na binding site 1 [ion binding]; other site
1311760005381	putative substrate binding site 2 [chemical binding]; other site
1311760005382	glutaredoxin 1; Provisional; Region: grxA; PRK11200
1311760005383	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1311760005384	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1311760005385	ATP binding site [chemical binding]; other site
1311760005386	Mg++ binding site [ion binding]; other site
1311760005387	motif III; other site
1311760005388	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760005389	nucleotide binding region [chemical binding]; other site
1311760005390	ATP-binding site [chemical binding]; other site
1311760005391	Protein of unknown function (DUF406); Region: DUF406; pfam04175
1311760005392	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1311760005393	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1311760005394	catalytic residues [active]
1311760005395	hinge region; other site
1311760005396	alpha helical domain; other site
1311760005397	Protein of unknown function (DUF1040); Region: DUF1040; cl01176
1311760005398	putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB; Provisional; Region: PRK14489
1311760005399	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1311760005400	GTP binding site; other site
1311760005401	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1311760005402	Walker A motif; other site
1311760005403	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1311760005404	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
1311760005405	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1311760005406	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1311760005407	AMP binding site [chemical binding]; other site
1311760005408	metal binding site [ion binding]; metal-binding site
1311760005409	active site
1311760005410	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1311760005411	active site
1311760005412	phosphate binding residues; other site
1311760005413	catalytic residues [active]
1311760005414	Pirin-related protein [General function prediction only]; Region: COG1741
1311760005415	Pirin; Region: Pirin; pfam02678
1311760005416	hypothetical protein; Provisional; Region: PRK11212
1311760005417	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1311760005418	active site
1311760005419	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1311760005420	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760005421	Walker A/P-loop; other site
1311760005422	ATP binding site [chemical binding]; other site
1311760005423	Q-loop/lid; other site
1311760005424	ABC transporter signature motif; other site
1311760005425	Walker B; other site
1311760005426	D-loop; other site
1311760005427	H-loop/switch region; other site
1311760005428	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1311760005429	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760005430	dimer interface [polypeptide binding]; other site
1311760005431	conserved gate region; other site
1311760005432	putative PBP binding loops; other site
1311760005433	ABC-ATPase subunit interface; other site
1311760005434	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1311760005435	dimerization domain swap beta strand [polypeptide binding]; other site
1311760005436	regulatory protein interface [polypeptide binding]; other site
1311760005437	active site
1311760005438	regulatory phosphorylation site [posttranslational modification]; other site
1311760005439	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1311760005440	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1311760005441	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1311760005442	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1311760005443	PTS system glucose-specific transporter subunit; Provisional; Region: PRK09439
1311760005444	HPr interaction site; other site
1311760005445	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1311760005446	active site
1311760005447	phosphorylation site [posttranslational modification]
1311760005448	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1311760005449	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1311760005450	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760005451	FeS/SAM binding site; other site
1311760005452	TRAM domain; Region: TRAM; pfam01938
1311760005453	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1311760005454	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1311760005455	putative substrate binding site [chemical binding]; other site
1311760005456	putative ATP binding site [chemical binding]; other site
1311760005457	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1311760005458	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1311760005459	substrate binding [chemical binding]; other site
1311760005460	active site
1311760005461	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1311760005462	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
1311760005463	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760005464	DNA binding site [nucleotide binding]
1311760005465	domain linker motif; other site
1311760005466	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1311760005467	dimerization interface [polypeptide binding]; other site
1311760005468	ligand binding site [chemical binding]; other site
1311760005469	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1311760005470	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1311760005471	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1311760005472	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1311760005473	Zn2+ binding site [ion binding]; other site
1311760005474	Mg2+ binding site [ion binding]; other site
1311760005475	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1311760005476	synthetase active site [active]
1311760005477	NTP binding site [chemical binding]; other site
1311760005478	metal binding site [ion binding]; metal-binding site
1311760005479	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1311760005480	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1311760005481	Abi-like protein; Region: Abi_2; cl01988
1311760005482	ferrochelatase; Reviewed; Region: hemH; PRK00035
1311760005483	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1311760005484	C-terminal domain interface [polypeptide binding]; other site
1311760005485	active site
1311760005486	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1311760005487	active site
1311760005488	N-terminal domain interface [polypeptide binding]; other site
1311760005489	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1311760005490	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1311760005491	Haemolytic domain; Region: Haemolytic; pfam01809
1311760005492	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1311760005493	Chain length determinant protein [Cell envelope biogenesis, outer membrane]; Region: WzzB; COG3765
1311760005494	Chain length determinant protein; Region: Wzz; pfam02706
1311760005495	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
1311760005496	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1311760005497	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1311760005498	active site
1311760005499	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1311760005500	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1311760005501	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1311760005502	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1311760005503	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1311760005504	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1311760005505	metal binding triad [ion binding]; metal-binding site
1311760005506	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1311760005507	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1311760005508	NAD binding site [chemical binding]; other site
1311760005509	substrate binding site [chemical binding]; other site
1311760005510	homodimer interface [polypeptide binding]; other site
1311760005511	active site
1311760005512	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1311760005513	O-Antigen ligase; Region: Wzy_C; pfam04932
1311760005514	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1311760005515	putative active site [active]
1311760005516	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1311760005517	DNA primase; Validated; Region: dnaG; PRK05667
1311760005518	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1311760005519	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1311760005520	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1311760005521	active site
1311760005522	metal binding site [ion binding]; metal-binding site
1311760005523	interdomain interaction site; other site
1311760005524	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1311760005525	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1311760005526	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1311760005527	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1311760005528	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1311760005529	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1311760005530	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760005531	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1311760005532	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1311760005533	DNA binding residues [nucleotide binding]
1311760005534	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1311760005535	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1311760005536	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1311760005537	UbiA prenyltransferase family; Region: UbiA; pfam01040
1311760005538	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1311760005539	homodimer interaction site [polypeptide binding]; other site
1311760005540	cofactor binding site; other site
1311760005541	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1311760005542	Protein of unknown function (DUF541); Region: SIMPL; cl01077
1311760005543	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1311760005544	amphipathic channel; other site
1311760005545	Asn-Pro-Ala signature motifs; other site
1311760005546	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
1311760005547	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1311760005548	threonine dehydratase; Reviewed; Region: PRK09224
1311760005549	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1311760005550	tetramer interface [polypeptide binding]; other site
1311760005551	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760005552	catalytic residue [active]
1311760005553	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1311760005554	putative Ile/Val binding site [chemical binding]; other site
1311760005555	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1311760005556	putative Ile/Val binding site [chemical binding]; other site
1311760005557	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1311760005558	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1311760005559	active site
1311760005560	substrate binding site [chemical binding]; other site
1311760005561	metal binding site [ion binding]; metal-binding site
1311760005562	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1311760005563	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1311760005564	active site
1311760005565	dimer interface [polypeptide binding]; other site
1311760005566	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1311760005567	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1311760005568	ligand binding site [chemical binding]; other site
1311760005569	NAD binding site [chemical binding]; other site
1311760005570	tetramer interface [polypeptide binding]; other site
1311760005571	catalytic site [active]
1311760005572	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1311760005573	L-serine binding site [chemical binding]; other site
1311760005574	ACT domain interface; other site
1311760005575	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1311760005576	two-component response regulator; Provisional; Region: PRK11173
1311760005577	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1311760005578	active site
1311760005579	phosphorylation site [posttranslational modification]
1311760005580	intermolecular recognition site; other site
1311760005581	dimerization interface [polypeptide binding]; other site
1311760005582	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1311760005583	DNA binding site [nucleotide binding]
1311760005584	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1311760005585	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1311760005586	active site
1311760005587	metal binding site [ion binding]; metal-binding site
1311760005588	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1311760005589	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1311760005590	active site
1311760005591	nucleotide binding site [chemical binding]; other site
1311760005592	HIGH motif; other site
1311760005593	KMSKS motif; other site
1311760005594	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1311760005595	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1311760005596	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1311760005597	active site
1311760005598	Riboflavin kinase; Region: Flavokinase; smart00904
1311760005599	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1311760005600	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1311760005601	active site
1311760005602	HIGH motif; other site
1311760005603	nucleotide binding site [chemical binding]; other site
1311760005604	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1311760005605	active site
1311760005606	KMSKS motif; other site
1311760005607	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1311760005608	tRNA binding surface [nucleotide binding]; other site
1311760005609	anticodon binding site; other site
1311760005610	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1311760005611	Tannase and feruloyl esterase; Region: Tannase; pfam07519
1311760005612	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1311760005613	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1311760005614	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1311760005615	domain interface [polypeptide binding]; other site
1311760005616	putative active site [active]
1311760005617	catalytic site [active]
1311760005618	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1311760005619	domain interface [polypeptide binding]; other site
1311760005620	putative active site [active]
1311760005621	catalytic site [active]
1311760005622	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1311760005623	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1311760005624	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1311760005625	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1311760005626	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760005627	Walker A/P-loop; other site
1311760005628	ATP binding site [chemical binding]; other site
1311760005629	Q-loop/lid; other site
1311760005630	ABC transporter signature motif; other site
1311760005631	Walker B; other site
1311760005632	D-loop; other site
1311760005633	H-loop/switch region; other site
1311760005634	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1311760005635	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760005636	Walker A/P-loop; other site
1311760005637	ATP binding site [chemical binding]; other site
1311760005638	Q-loop/lid; other site
1311760005639	ABC transporter signature motif; other site
1311760005640	Walker B; other site
1311760005641	D-loop; other site
1311760005642	H-loop/switch region; other site
1311760005643	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1311760005644	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760005645	dimer interface [polypeptide binding]; other site
1311760005646	conserved gate region; other site
1311760005647	putative PBP binding loops; other site
1311760005648	ABC-ATPase subunit interface; other site
1311760005649	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1311760005650	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760005651	dimer interface [polypeptide binding]; other site
1311760005652	conserved gate region; other site
1311760005653	putative PBP binding loops; other site
1311760005654	ABC-ATPase subunit interface; other site
1311760005655	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760005656	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
1311760005657	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1311760005658	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1311760005659	G1 box; other site
1311760005660	putative GEF interaction site [polypeptide binding]; other site
1311760005661	GTP/Mg2+ binding site [chemical binding]; other site
1311760005662	Switch I region; other site
1311760005663	G2 box; other site
1311760005664	G3 box; other site
1311760005665	Switch II region; other site
1311760005666	G4 box; other site
1311760005667	G5 box; other site
1311760005668	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1311760005669	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1311760005670	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1311760005671	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1311760005672	putative active site [active]
1311760005673	catalytic residue [active]
1311760005674	GTP-binding protein YchF; Reviewed; Region: PRK09601
1311760005675	YchF GTPase; Region: YchF; cd01900
1311760005676	G1 box; other site
1311760005677	GTP/Mg2+ binding site [chemical binding]; other site
1311760005678	Switch I region; other site
1311760005679	G2 box; other site
1311760005680	Switch II region; other site
1311760005681	G3 box; other site
1311760005682	G4 box; other site
1311760005683	G5 box; other site
1311760005684	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1311760005685	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1311760005686	L-lactate permease; Region: Lactate_perm; cl00701
1311760005687	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1311760005688	Cysteine-rich domain; Region: CCG; pfam02754
1311760005689	Cysteine-rich domain; Region: CCG; pfam02754
1311760005690	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1311760005691	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1311760005692	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1311760005693	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1311760005694	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1311760005695	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1311760005696	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1311760005697	ribonuclease PH; Reviewed; Region: rph; PRK00173
1311760005698	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1311760005699	hexamer interface [polypeptide binding]; other site
1311760005700	active site
1311760005701	hypothetical protein; Provisional; Region: PRK11820
1311760005702	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1311760005703	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1311760005704	putative global regulator; Reviewed; Region: PRK09559
1311760005705	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1311760005706	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1311760005707	D-ribose pyranase; Provisional; Region: PRK11797
1311760005708	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1311760005709	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1311760005710	Walker A/P-loop; other site
1311760005711	ATP binding site [chemical binding]; other site
1311760005712	Q-loop/lid; other site
1311760005713	ABC transporter signature motif; other site
1311760005714	Walker B; other site
1311760005715	D-loop; other site
1311760005716	H-loop/switch region; other site
1311760005717	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1311760005718	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1311760005719	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1311760005720	TM-ABC transporter signature motif; other site
1311760005721	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1311760005722	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1311760005723	ligand binding site [chemical binding]; other site
1311760005724	dimerization interface [polypeptide binding]; other site
1311760005725	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1311760005726	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1311760005727	substrate binding site [chemical binding]; other site
1311760005728	dimer interface [polypeptide binding]; other site
1311760005729	ATP binding site [chemical binding]; other site
1311760005730	transcriptional repressor RbsR; Provisional; Region: PRK10423
1311760005731	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760005732	DNA binding site [nucleotide binding]
1311760005733	domain linker motif; other site
1311760005734	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1311760005735	dimerization interface [polypeptide binding]; other site
1311760005736	ligand binding site [chemical binding]; other site
1311760005737	transcriptional regulator NarP; Provisional; Region: PRK10403
1311760005738	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1311760005739	active site
1311760005740	phosphorylation site [posttranslational modification]
1311760005741	intermolecular recognition site; other site
1311760005742	dimerization interface [polypeptide binding]; other site
1311760005743	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1311760005744	DNA binding residues [nucleotide binding]
1311760005745	dimerization interface [polypeptide binding]; other site
1311760005746	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1311760005747	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1311760005748	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1311760005749	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1311760005750	putative RNA binding site [nucleotide binding]; other site
1311760005751	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760005752	S-adenosylmethionine binding site [chemical binding]; other site
1311760005753	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1311760005754	BRO family, N-terminal domain; Region: Bro-N; smart01040
1311760005755	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1311760005756	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1311760005757	active site
1311760005758	trimer interface [polypeptide binding]; other site
1311760005759	allosteric site; other site
1311760005760	active site lid [active]
1311760005761	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1311760005762	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1311760005763	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1311760005764	active site
1311760005765	dimer interface [polypeptide binding]; other site
1311760005766	Uncharacterized protein conserved in bacteria (DUF2322); Region: DUF2322; pfam10084
1311760005767	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1311760005768	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1311760005769	active site
1311760005770	HIGH motif; other site
1311760005771	dimer interface [polypeptide binding]; other site
1311760005772	KMSKS motif; other site
1311760005773	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760005774	RNA binding surface [nucleotide binding]; other site
1311760005775	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
1311760005776	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1311760005777	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1311760005778	active site
1311760005779	catalytic residues [active]
1311760005780	metal binding site [ion binding]; metal-binding site
1311760005781	homodimer binding site [polypeptide binding]; other site
1311760005782	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1311760005783	carboxyltransferase (CT) interaction site; other site
1311760005784	biotinylation site [posttranslational modification]; other site
1311760005785	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1311760005786	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1311760005787	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1311760005788	putative active site [active]
1311760005789	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1311760005790	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1311760005791	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1311760005792	DNA ligase; Provisional; Region: PRK09125
1311760005793	Adenylation domain of kDNA ligases and similar proteins; Region: Adenylation_kDNA_ligase_like; cd07896
1311760005794	DNA binding site [nucleotide binding]
1311760005795	active site
1311760005796	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of kDNA ligase-like ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_kDNA_ligase_like; cd08041
1311760005797	DNA binding site [nucleotide binding]
1311760005798	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1311760005799	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1311760005800	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1311760005801	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
1311760005802	G1 box; other site
1311760005803	GTP/Mg2+ binding site [chemical binding]; other site
1311760005804	Switch I region; other site
1311760005805	G2 box; other site
1311760005806	G3 box; other site
1311760005807	Switch II region; other site
1311760005808	G4 box; other site
1311760005809	G5 box; other site
1311760005810	RNase E inhibitor protein; Provisional; Region: PRK11191
1311760005811	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1311760005812	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1311760005813	CPxP  motif; other site
1311760005814	proline dipeptidase; Provisional; Region: PRK13607
1311760005815	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1311760005816	active site
1311760005817	phage T7 F exclusion suppressor FxsA; Reviewed; Region: fxsA; PRK11463
1311760005818	EamA-like transporter family; Region: EamA; pfam00892
1311760005819	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1311760005820	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1311760005821	active site
1311760005822	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1311760005823	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1311760005824	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1311760005825	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1311760005826	putative NADH binding site [chemical binding]; other site
1311760005827	putative active site [active]
1311760005828	nudix motif; other site
1311760005829	putative metal binding site [ion binding]; other site
1311760005830	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
1311760005831	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1311760005832	active site
1311760005833	dimer interface [polypeptide binding]; other site
1311760005834	catalytic residues [active]
1311760005835	effector binding site; other site
1311760005836	R2 peptide binding site; other site
1311760005837	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1311760005838	dimer interface [polypeptide binding]; other site
1311760005839	putative radical transfer pathway; other site
1311760005840	diiron center [ion binding]; other site
1311760005841	tyrosyl radical; other site
1311760005842	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1311760005843	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1311760005844	FMN binding site [chemical binding]; other site
1311760005845	active site
1311760005846	catalytic residues [active]
1311760005847	substrate binding site [chemical binding]; other site
1311760005848	Uncharacterized integral membrane protein (DUF2301); Region: DUF2301; cl02241
1311760005849	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1311760005850	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1311760005851	substrate binding site [chemical binding]; other site
1311760005852	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1311760005853	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1311760005854	substrate binding site [chemical binding]; other site
1311760005855	ligand binding site [chemical binding]; other site
1311760005856	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1311760005857	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1311760005858	peptide binding site [polypeptide binding]; other site
1311760005859	Acylphosphatase; Region: Acylphosphatase; cl00551
1311760005860	aminopeptidase N; Provisional; Region: pepN; PRK14015
1311760005861	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1311760005862	active site
1311760005863	Zn binding site [ion binding]; other site
1311760005864	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugZ; COG0748
1311760005865	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1311760005866	Haem utilisation ChuX/HutX; Region: ChuX_HutX; cl01509
1311760005867	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1311760005868	aromatic amino acid transport protein; Region: araaP; TIGR00837
1311760005869	transcription-repair coupling factor; Provisional; Region: PRK10689
1311760005870	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1311760005871	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760005872	ATP binding site [chemical binding]; other site
1311760005873	putative Mg++ binding site [ion binding]; other site
1311760005874	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760005875	nucleotide binding region [chemical binding]; other site
1311760005876	ATP-binding site [chemical binding]; other site
1311760005877	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1311760005878	Protein of unknown function (DUF497); Region: DUF497; pfam04365
1311760005879	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
1311760005880	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1311760005881	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1311760005882	oligomeric interface; other site
1311760005883	putative active site [active]
1311760005884	homodimer interface [polypeptide binding]; other site
1311760005885	peptidase T; Region: peptidase-T; TIGR01882
1311760005886	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1311760005887	metal binding site [ion binding]; metal-binding site
1311760005888	dimer interface [polypeptide binding]; other site
1311760005889	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1311760005890	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1311760005891	putative NAD(P) binding site [chemical binding]; other site
1311760005892	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1311760005893	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760005894	ABC-ATPase subunit  interface; other site
1311760005895	dimer interface [polypeptide binding]; other site
1311760005896	putative PBP binding regions; other site
1311760005897	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1311760005898	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760005899	ABC-ATPase subunit  interface; other site
1311760005900	dimer interface [polypeptide binding]; other site
1311760005901	putative PBP binding regions; other site
1311760005902	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1311760005903	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1311760005904	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1311760005905	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1311760005906	metal binding site [ion binding]; metal-binding site
1311760005907	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1311760005908	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760005909	FeS/SAM binding site; other site
1311760005910	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760005911	non-specific DNA binding site [nucleotide binding]; other site
1311760005912	salt bridge; other site
1311760005913	sequence-specific DNA binding site [nucleotide binding]; other site
1311760005914	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1311760005915	TPR repeat; Region: TPR_11; pfam13414
1311760005916	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1311760005917	binding surface
1311760005918	TPR motif; other site
1311760005919	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1311760005920	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1311760005921	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1311760005922	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1311760005923	RNA binding site [nucleotide binding]; other site
1311760005924	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1311760005925	putative FMN binding site [chemical binding]; other site
1311760005926	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
1311760005927	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1311760005928	tandem repeat interface [polypeptide binding]; other site
1311760005929	oligomer interface [polypeptide binding]; other site
1311760005930	active site residues [active]
1311760005931	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1311760005932	tandem repeat interface [polypeptide binding]; other site
1311760005933	oligomer interface [polypeptide binding]; other site
1311760005934	active site residues [active]
1311760005935	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1311760005936	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1311760005937	Na binding site [ion binding]; other site
1311760005938	HMP-P kinase/thiamin-monophosphate pyrophosphorylase; Region: PLN02898
1311760005939	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1311760005940	dimer interface [polypeptide binding]; other site
1311760005941	substrate binding site [chemical binding]; other site
1311760005942	ATP binding site [chemical binding]; other site
1311760005943	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1311760005944	thiamine phosphate binding site [chemical binding]; other site
1311760005945	active site
1311760005946	pyrophosphate binding site [ion binding]; other site
1311760005947	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760005948	metabolite-proton symporter; Region: 2A0106; TIGR00883
1311760005949	putative substrate translocation pore; other site
1311760005950	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1311760005951	substrate binding site [chemical binding]; other site
1311760005952	multimerization interface [polypeptide binding]; other site
1311760005953	ATP binding site [chemical binding]; other site
1311760005954	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK08271
1311760005955	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1311760005956	effector binding site; other site
1311760005957	active site
1311760005958	Zn binding site [ion binding]; other site
1311760005959	glycine loop; other site
1311760005960	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1311760005961	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1311760005962	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1311760005963	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1311760005964	PYR/PP interface [polypeptide binding]; other site
1311760005965	dimer interface [polypeptide binding]; other site
1311760005966	TPP binding site [chemical binding]; other site
1311760005967	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1311760005968	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1311760005969	TPP-binding site [chemical binding]; other site
1311760005970	dimer interface [polypeptide binding]; other site
1311760005971	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1311760005972	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1311760005973	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1311760005974	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1311760005975	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1311760005976	cytochrome c nitrate reductase biogenesis protein NrfE; Region: cyt_nit_nrfE; TIGR03145
1311760005977	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1311760005978	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1311760005979	cytochrome c nitrite reductase, accessory protein NrfF; Region: cyt_nit_nrfF; TIGR03147
1311760005980	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1311760005981	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1311760005982	binding surface
1311760005983	TPR motif; other site
1311760005984	serine endoprotease; Provisional; Region: PRK10942
1311760005985	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1311760005986	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1311760005987	protein binding site [polypeptide binding]; other site
1311760005988	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1311760005989	protein binding site [polypeptide binding]; other site
1311760005990	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1311760005991	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1311760005992	Walker A/P-loop; other site
1311760005993	ATP binding site [chemical binding]; other site
1311760005994	Q-loop/lid; other site
1311760005995	ABC transporter signature motif; other site
1311760005996	Walker B; other site
1311760005997	D-loop; other site
1311760005998	H-loop/switch region; other site
1311760005999	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1311760006000	conserved hypothetical integral membrane protein; Region: TIGR00056
1311760006001	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1311760006002	mce related protein; Region: MCE; pfam02470
1311760006003	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; cl01074
1311760006004	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1311760006005	anti sigma factor interaction site; other site
1311760006006	regulatory phosphorylation site [posttranslational modification]; other site
1311760006007	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1311760006008	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1311760006009	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1311760006010	hinge; other site
1311760006011	active site
1311760006012	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1311760006013	active site
1311760006014	putative DNA-binding cleft [nucleotide binding]; other site
1311760006015	dimer interface [polypeptide binding]; other site
1311760006016	hypothetical protein; Validated; Region: PRK00110
1311760006017	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1311760006018	nudix motif; other site
1311760006019	Uncharacterized conserved protein [Function unknown]; Region: COG1801
1311760006020	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1311760006021	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1311760006022	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760006023	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760006024	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760006025	Catalytic site [active]
1311760006026	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1311760006027	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760006028	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
1311760006029	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
1311760006030	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1311760006031	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
1311760006032	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
1311760006033	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
1311760006034	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
1311760006035	Phage P2 GpU; Region: Phage_P2_GpU; cl01391
1311760006036	Phage Tail Protein X; Region: Phage_tail_X; cl02088
1311760006037	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1311760006038	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1311760006039	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1311760006040	Baseplate J-like protein; Region: Baseplate_J; cl01294
1311760006041	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817
1311760006042	N-terminal domain of PARMER_03128; Region: PARMER_03128_N; cd12106
1311760006043	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1311760006044	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1311760006045	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1311760006046	dimer interface [polypeptide binding]; other site
1311760006047	anticodon binding site; other site
1311760006048	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1311760006049	homodimer interface [polypeptide binding]; other site
1311760006050	motif 1; other site
1311760006051	active site
1311760006052	motif 2; other site
1311760006053	GAD domain; Region: GAD; pfam02938
1311760006054	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1311760006055	active site
1311760006056	motif 3; other site
1311760006057	Predicted membrane protein [Function unknown]; Region: COG2431
1311760006058	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1311760006059	active site
1311760006060	DNA polymerase IV; Validated; Region: PRK02406
1311760006061	DNA binding site [nucleotide binding]
1311760006062	heat shock protein HtpX; Provisional; Region: PRK05457
1311760006063	Predicted membrane protein [Function unknown]; Region: COG1238
1311760006064	formate transporter FocA; Region: formate_focA; TIGR04060
1311760006065	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1311760006066	Pyruvate formate lyase 1; Region: PFL1; cd01678
1311760006067	coenzyme A binding site [chemical binding]; other site
1311760006068	active site
1311760006069	catalytic residues [active]
1311760006070	glycine loop; other site
1311760006071	Virulence protein [General function prediction only]; Region: COG3943
1311760006072	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1311760006073	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1311760006074	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760006075	FeS/SAM binding site; other site
1311760006076	oligopeptidase A; Provisional; Region: PRK10911
1311760006077	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1311760006078	active site
1311760006079	Zn binding site [ion binding]; other site
1311760006080	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1311760006081	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1311760006082	Prephenate dehydratase; Region: PDT; pfam00800
1311760006083	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1311760006084	putative L-Phe binding site [chemical binding]; other site
1311760006085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
1311760006086	adenylate kinase; Reviewed; Region: adk; PRK00279
1311760006087	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1311760006088	AMP-binding site [chemical binding]; other site
1311760006089	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1311760006090	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
1311760006091	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1311760006092	ligand-binding site [chemical binding]; other site
1311760006093	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1311760006094	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1311760006095	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1311760006096	intersubunit interface [polypeptide binding]; other site
1311760006097	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1311760006098	Walker A/P-loop; other site
1311760006099	ATP binding site [chemical binding]; other site
1311760006100	ABC transporter; Region: ABC_tran; pfam00005
1311760006101	Q-loop/lid; other site
1311760006102	ABC transporter signature motif; other site
1311760006103	Walker B; other site
1311760006104	D-loop; other site
1311760006105	H-loop/switch region; other site
1311760006106	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1311760006107	AmpG-like permease; Region: 2A0125; TIGR00901
1311760006108	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1311760006109	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1311760006110	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1311760006111	substrate binding pocket [chemical binding]; other site
1311760006112	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1311760006113	B12 binding site [chemical binding]; other site
1311760006114	cobalt ligand [ion binding]; other site
1311760006115	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1311760006116	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1311760006117	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1311760006118	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1311760006119	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1311760006120	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760006121	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760006122	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1311760006123	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1311760006124	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1311760006125	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1311760006126	Walker A/P-loop; other site
1311760006127	ATP binding site [chemical binding]; other site
1311760006128	Q-loop/lid; other site
1311760006129	ABC transporter signature motif; other site
1311760006130	Walker B; other site
1311760006131	D-loop; other site
1311760006132	H-loop/switch region; other site
1311760006133	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1311760006134	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1311760006135	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760006136	putative PBP binding regions; other site
1311760006137	ABC-ATPase subunit  interface; other site
1311760006138	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
1311760006139	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
1311760006140	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1311760006141	FAD binding site [chemical binding]; other site
1311760006142	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1311760006143	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1311760006144	NAD binding site [chemical binding]; other site
1311760006145	homodimer interface [polypeptide binding]; other site
1311760006146	active site
1311760006147	substrate binding site [chemical binding]; other site
1311760006148	Trm112p-like protein; Region: Trm112p; cl01066
1311760006149	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1311760006150	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1311760006151	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1311760006152	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1311760006153	non-specific DNA binding site [nucleotide binding]; other site
1311760006154	salt bridge; other site
1311760006155	sequence-specific DNA binding site [nucleotide binding]; other site
1311760006156	Fic family protein [Function unknown]; Region: COG3177
1311760006157	Fic/DOC family; Region: Fic; pfam02661
1311760006158	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1311760006159	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
1311760006160	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760006161	Walker A motif; other site
1311760006162	ATP binding site [chemical binding]; other site
1311760006163	Walker B motif; other site
1311760006164	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1311760006165	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1311760006166	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1311760006167	oligomer interface [polypeptide binding]; other site
1311760006168	active site residues [active]
1311760006169	Fe-S metabolism associated domain; Region: SufE; cl00951
1311760006170	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1311760006171	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006172	S-adenosylmethionine binding site [chemical binding]; other site
1311760006173	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1311760006174	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1311760006175	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1311760006176	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1311760006177	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1311760006178	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1311760006179	glutamine binding [chemical binding]; other site
1311760006180	catalytic triad [active]
1311760006181	anthranilate synthase component I; Provisional; Region: PRK13564
1311760006182	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1311760006183	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1311760006184	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1311760006185	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1311760006186	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760006187	RNA binding surface [nucleotide binding]; other site
1311760006188	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1311760006189	probable active site [active]
1311760006190	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1311760006191	transmembrane helices; other site
1311760006192	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1311760006193	TrkA-C domain; Region: TrkA_C; pfam02080
1311760006194	TrkA-C domain; Region: TrkA_C; pfam02080
1311760006195	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1311760006196	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1311760006197	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1311760006198	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1311760006199	trimer interface [polypeptide binding]; other site
1311760006200	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760006201	trimer interface [polypeptide binding]; other site
1311760006202	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760006203	trimer interface [polypeptide binding]; other site
1311760006204	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1311760006205	trimer interface [polypeptide binding]; other site
1311760006206	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1311760006207	YadA-like C-terminal region; Region: YadA; pfam03895
1311760006208	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
1311760006209	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1311760006210	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1311760006211	Colicin pore forming domain; Region: Colicin; pfam01024
1311760006212	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1311760006213	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1311760006214	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1311760006215	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1311760006216	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1311760006217	primosomal replication protein N; Provisional; Region: PRK02801
1311760006218	generic binding surface II; other site
1311760006219	generic binding surface I; other site
1311760006220	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1311760006221	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1311760006222	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1311760006223	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1311760006224	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1311760006225	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1311760006226	active site
1311760006227	catalytic site [active]
1311760006228	substrate binding site [chemical binding]; other site
1311760006229	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1311760006230	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760006231	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760006232	ABC transporter; Region: ABC_tran_2; pfam12848
1311760006233	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760006234	electron transport complex protein RsxA; Provisional; Region: PRK05151
1311760006235	ferredoxin; Provisional; Region: PRK08764
1311760006236	Putative Fe-S cluster; Region: FeS; pfam04060
1311760006237	4Fe-4S binding domain; Region: Fer4; pfam00037
1311760006238	4Fe-4S binding domain; Region: Fer4; cl02805
1311760006239	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1311760006240	SLBB domain; Region: SLBB; pfam10531
1311760006241	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1311760006242	Predicted membrane protein [Function unknown]; Region: COG2860
1311760006243	UPF0126 domain; Region: UPF0126; pfam03458
1311760006244	UPF0126 domain; Region: UPF0126; pfam03458
1311760006245	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1311760006246	electron transport complex protein RnfG; Validated; Region: PRK01908
1311760006247	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1311760006248	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1311760006249	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1311760006250	putative acyl-acceptor binding pocket; other site
1311760006251	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760006252	active site
1311760006253	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1311760006254	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760006255	Walker A motif; other site
1311760006256	ATP binding site [chemical binding]; other site
1311760006257	Walker B motif; other site
1311760006258	arginine finger; other site
1311760006259	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1311760006260	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1311760006261	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1311760006262	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1311760006263	Walker A/P-loop; other site
1311760006264	ATP binding site [chemical binding]; other site
1311760006265	Q-loop/lid; other site
1311760006266	ABC transporter signature motif; other site
1311760006267	Walker B; other site
1311760006268	D-loop; other site
1311760006269	H-loop/switch region; other site
1311760006270	inner membrane transport permease; Provisional; Region: PRK15066
1311760006271	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1311760006272	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1311760006273	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1311760006274	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1311760006275	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760006276	dimer interface [polypeptide binding]; other site
1311760006277	conserved gate region; other site
1311760006278	putative PBP binding loops; other site
1311760006279	ABC-ATPase subunit interface; other site
1311760006280	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1311760006281	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760006282	Walker A/P-loop; other site
1311760006283	ATP binding site [chemical binding]; other site
1311760006284	Q-loop/lid; other site
1311760006285	ABC transporter signature motif; other site
1311760006286	Walker B; other site
1311760006287	D-loop; other site
1311760006288	H-loop/switch region; other site
1311760006289	TOBE domain; Region: TOBE; cl01440
1311760006290	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1311760006291	putative coenzyme Q binding site [chemical binding]; other site
1311760006292	hypothetical protein; Validated; Region: PRK01777
1311760006293	benzoate transport; Region: 2A0115; TIGR00895
1311760006294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760006295	putative substrate translocation pore; other site
1311760006296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760006297	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1311760006298	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1311760006299	metal binding site [ion binding]; metal-binding site
1311760006300	dimer interface [polypeptide binding]; other site
1311760006301	Lipoprotein GNA1870 C terminal like; Region: Lipoprot_C; pfam08794
1311760006302	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1311760006303	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1311760006304	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760006305	active site
1311760006306	Guanylate kinase; Region: Guanylate_kin; pfam00625
1311760006307	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1311760006308	catalytic site [active]
1311760006309	G-X2-G-X-G-K; other site
1311760006310	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1311760006311	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1311760006312	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1311760006313	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1311760006314	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1311760006315	molybdopterin cofactor binding site; other site
1311760006316	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1311760006317	putative molybdopterin cofactor binding site [chemical binding]; other site
1311760006318	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1311760006319	putative molybdopterin cofactor binding site; other site
1311760006320	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1311760006321	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1311760006322	4Fe-4S binding domain; Region: Fer4; pfam00037
1311760006323	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1311760006324	PIN domain; Region: PIN_3; cl17397
1311760006325	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1311760006326	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1311760006327	dimer interface [polypeptide binding]; other site
1311760006328	phosphorylation site [posttranslational modification]
1311760006329	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1311760006330	ATP binding site [chemical binding]; other site
1311760006331	Mg2+ binding site [ion binding]; other site
1311760006332	G-X-G motif; other site
1311760006333	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1311760006334	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1311760006335	active site
1311760006336	phosphorylation site [posttranslational modification]
1311760006337	intermolecular recognition site; other site
1311760006338	dimerization interface [polypeptide binding]; other site
1311760006339	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1311760006340	DNA binding residues [nucleotide binding]
1311760006341	dimerization interface [polypeptide binding]; other site
1311760006342	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1311760006343	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1311760006344	Ligand Binding Site [chemical binding]; other site
1311760006345	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1311760006346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006347	S-adenosylmethionine binding site [chemical binding]; other site
1311760006348	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
1311760006349	DNA gyrase subunit A; Validated; Region: PRK05560
1311760006350	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1311760006351	CAP-like domain; other site
1311760006352	active site
1311760006353	primary dimer interface [polypeptide binding]; other site
1311760006354	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006355	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006356	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006357	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006358	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006359	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1311760006360	ABC transporter ATPase component; Reviewed; Region: PRK11147
1311760006361	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1311760006362	Walker A/P-loop; other site
1311760006363	ATP binding site [chemical binding]; other site
1311760006364	ABC transporter signature motif; other site
1311760006365	Walker B; other site
1311760006366	D-loop; other site
1311760006367	H-loop/switch region; other site
1311760006368	ABC transporter; Region: ABC_tran_2; pfam12848
1311760006369	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1311760006370	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1311760006371	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1311760006372	putative ATP binding site [chemical binding]; other site
1311760006373	putative substrate interface [chemical binding]; other site
1311760006374	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1311760006375	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1311760006376	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1311760006377	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1311760006378	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1311760006379	putative active site [active]
1311760006380	putative metal-binding site [ion binding]; other site
1311760006381	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1311760006382	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1311760006383	Walker A/P-loop; other site
1311760006384	ATP binding site [chemical binding]; other site
1311760006385	Q-loop/lid; other site
1311760006386	ABC transporter signature motif; other site
1311760006387	Walker B; other site
1311760006388	D-loop; other site
1311760006389	H-loop/switch region; other site
1311760006390	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1311760006391	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760006392	dimer interface [polypeptide binding]; other site
1311760006393	conserved gate region; other site
1311760006394	ABC-ATPase subunit interface; other site
1311760006395	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1311760006396	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1311760006397	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1311760006398	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1311760006399	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1311760006400	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1311760006401	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1311760006402	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1311760006403	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1311760006404	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1311760006405	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1311760006406	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1311760006407	nucleophile elbow; other site
1311760006408	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1311760006409	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2; cl00208
1311760006410	CAS motifs; other site
1311760006411	active site
1311760006412	hypothetical protein; Provisional; Region: PRK04860
1311760006413	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1311760006414	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1311760006415	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1311760006416	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1311760006417	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1311760006418	AzlC protein; Region: AzlC; pfam03591
1311760006419	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1311760006420	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1311760006421	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1311760006422	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1311760006423	Protein export membrane protein; Region: SecD_SecF; pfam02355
1311760006424	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1311760006425	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1311760006426	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1311760006427	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1311760006428	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1311760006429	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1311760006430	active site
1311760006431	catalytic residues [active]
1311760006432	galactokinase; Provisional; Region: PRK05101
1311760006433	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1311760006434	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1311760006435	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1311760006436	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1311760006437	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1311760006438	dimer interface [polypeptide binding]; other site
1311760006439	active site
1311760006440	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
1311760006441	phosphodiesterase YaeI; Provisional; Region: PRK11340
1311760006442	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1311760006443	putative active site [active]
1311760006444	putative metal binding site [ion binding]; other site
1311760006445	Predicted permeases [General function prediction only]; Region: COG0679
1311760006446	peptide chain release factor 2; Provisional; Region: PRK08787
1311760006447	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1311760006448	RF-1 domain; Region: RF-1; pfam00472
1311760006449	WYL domain; Region: WYL; pfam13280
1311760006450	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1311760006451	active site
1311760006452	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1311760006453	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760006454	Helix-turn-helix domain; Region: HTH_28; pfam13518
1311760006455	Homeodomain-like domain; Region: HTH_32; pfam13565
1311760006456	Integrase core domain; Region: rve; pfam00665
1311760006457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1311760006458	Integrase core domain; Region: rve_3; pfam13683
1311760006459	selenophosphate synthetase; Provisional; Region: PRK00943
1311760006460	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1311760006461	dimerization interface [polypeptide binding]; other site
1311760006462	putative ATP binding site [chemical binding]; other site
1311760006463	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1311760006464	nudix motif; other site
1311760006465	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1311760006466	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1311760006467	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1311760006468	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
1311760006469	active site
1311760006470	FMN binding site [chemical binding]; other site
1311760006471	substrate binding site [chemical binding]; other site
1311760006472	catalytic residues [active]
1311760006473	homodimer interface [polypeptide binding]; other site
1311760006474	Uncharacterized protein conserved in bacteria (DUF2251); Region: DUF2251; pfam10008
1311760006475	enolase; Provisional; Region: eno; PRK00077
1311760006476	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1311760006477	dimer interface [polypeptide binding]; other site
1311760006478	metal binding site [ion binding]; metal-binding site
1311760006479	substrate binding pocket [chemical binding]; other site
1311760006480	23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522
1311760006481	beta-hexosaminidase; Provisional; Region: PRK05337
1311760006482	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1311760006483	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1311760006484	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1311760006485	putative DNA-binding cleft [nucleotide binding]; other site
1311760006486	putative DNA clevage site; other site
1311760006487	molecular lever; other site
1311760006488	LexA repressor; Validated; Region: PRK00215
1311760006489	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1311760006490	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760006491	Catalytic site [active]
1311760006492	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1311760006493	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1311760006494	putative acyl-acceptor binding pocket; other site
1311760006495	Predicted membrane protein [Function unknown]; Region: COG1584
1311760006496	Cupin; Region: Cupin_6; pfam12852
1311760006497	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760006498	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1311760006499	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1311760006500	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1311760006501	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1311760006502	active site residue [active]
1311760006503	Predicted membrane protein [Function unknown]; Region: COG3059
1311760006504	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1311760006505	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1311760006506	ATP-grasp domain; Region: ATP-grasp; pfam02222
1311760006507	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1311760006508	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1311760006509	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1311760006510	active site turn [active]
1311760006511	phosphorylation site [posttranslational modification]
1311760006512	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1311760006513	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1311760006514	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
1311760006515	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1311760006516	YccA-like proteins; Region: YccA_like; cd10433
1311760006517	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1311760006518	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1311760006519	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1311760006520	GIY-YIG motif/motif A; other site
1311760006521	active site
1311760006522	catalytic site [active]
1311760006523	putative DNA binding site [nucleotide binding]; other site
1311760006524	metal binding site [ion binding]; metal-binding site
1311760006525	UvrB/uvrC motif; Region: UVR; pfam02151
1311760006526	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1311760006527	Helix-hairpin-helix motif; Region: HHH; pfam00633
1311760006528	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1311760006529	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1311760006530	23S rRNA binding site [nucleotide binding]; other site
1311760006531	L21 binding site [polypeptide binding]; other site
1311760006532	L13 binding site [polypeptide binding]; other site
1311760006533	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1311760006534	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1311760006535	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1311760006536	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1311760006537	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1311760006538	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760006539	ATP binding site [chemical binding]; other site
1311760006540	putative Mg++ binding site [ion binding]; other site
1311760006541	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760006542	nucleotide binding region [chemical binding]; other site
1311760006543	ATP-binding site [chemical binding]; other site
1311760006544	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1311760006545	HRDC domain; Region: HRDC; pfam00570
1311760006546	frataxin-like protein; Provisional; Region: cyaY; PRK00446
1311760006547	putative iron binding site [ion binding]; other site
1311760006548	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1311760006549	UGMP family protein; Validated; Region: PRK09604
1311760006550	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1311760006551	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1311760006552	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1311760006553	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760006554	RNA binding surface [nucleotide binding]; other site
1311760006555	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1311760006556	active site
1311760006557	Entericidin EcnA/B family; Region: Entericidin; cl02322
1311760006558	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1311760006559	30S subunit binding site; other site
1311760006560	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1311760006561	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1311760006562	putative acyl-acceptor binding pocket; other site
1311760006563	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1311760006564	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1311760006565	dimer interface [polypeptide binding]; other site
1311760006566	active site
1311760006567	catalytic residue [active]
1311760006568	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1311760006569	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1311760006570	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1311760006571	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1311760006572	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1311760006573	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1311760006574	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1311760006575	purine monophosphate binding site [chemical binding]; other site
1311760006576	dimer interface [polypeptide binding]; other site
1311760006577	putative catalytic residues [active]
1311760006578	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1311760006579	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1311760006580	Predicted acetyltransferase [General function prediction only]; Region: COG2388
1311760006581	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1311760006582	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1311760006583	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1311760006584	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1311760006585	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1311760006586	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1311760006587	active site
1311760006588	multimer interface [polypeptide binding]; other site
1311760006589	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1311760006590	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1311760006591	active site
1311760006592	HIGH motif; other site
1311760006593	KMSKS motif; other site
1311760006594	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1311760006595	tRNA binding surface [nucleotide binding]; other site
1311760006596	anticodon binding site; other site
1311760006597	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1311760006598	dimer interface [polypeptide binding]; other site
1311760006599	putative tRNA-binding site [nucleotide binding]; other site
1311760006600	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1311760006601	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1311760006602	active site
1311760006603	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1311760006604	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1311760006605	RNA binding surface [nucleotide binding]; other site
1311760006606	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1311760006607	active site
1311760006608	uracil binding [chemical binding]; other site
1311760006609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760006610	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1311760006611	putative substrate translocation pore; other site
1311760006612	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1311760006613	TRAM domain; Region: TRAM; pfam01938
1311760006614	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006615	S-adenosylmethionine binding site [chemical binding]; other site
1311760006616	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK05318
1311760006617	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1311760006618	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1311760006619	ATP-dependent helicase HepA; Validated; Region: PRK04914
1311760006620	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760006621	ATP binding site [chemical binding]; other site
1311760006622	putative Mg++ binding site [ion binding]; other site
1311760006623	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760006624	nucleotide binding region [chemical binding]; other site
1311760006625	ATP-binding site [chemical binding]; other site
1311760006626	Protein of unknown function (DUF497); Region: DUF497; pfam04365
1311760006627	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1311760006628	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1311760006629	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1311760006630	active site
1311760006631	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1311760006632	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1311760006633	amidase catalytic site [active]
1311760006634	Zn binding residues [ion binding]; other site
1311760006635	substrate binding site [chemical binding]; other site
1311760006636	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1311760006637	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760006638	active site
1311760006639	cystathionine beta-lyase; Provisional; Region: PRK08114
1311760006640	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1311760006641	homodimer interface [polypeptide binding]; other site
1311760006642	substrate-cofactor binding pocket; other site
1311760006643	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760006644	catalytic residue [active]
1311760006645	disulfide bond formation protein B; Provisional; Region: PRK01749
1311760006646	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1311760006647	fatty acid metabolism regulator; Provisional; Region: PRK04984
1311760006648	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1311760006649	DNA-binding site [nucleotide binding]; DNA binding site
1311760006650	FadR C-terminal domain; Region: FadR_C; pfam07840
1311760006651	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1311760006652	PhoH-like protein; Region: PhoH; pfam02562
1311760006653	transketolase; Reviewed; Region: PRK12753
1311760006654	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1311760006655	TPP-binding site [chemical binding]; other site
1311760006656	dimer interface [polypeptide binding]; other site
1311760006657	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1311760006658	PYR/PP interface [polypeptide binding]; other site
1311760006659	dimer interface [polypeptide binding]; other site
1311760006660	TPP binding site [chemical binding]; other site
1311760006661	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1311760006662	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1311760006663	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760006664	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1311760006665	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760006666	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1311760006667	putative active site [active]
1311760006668	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1311760006669	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760006670	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1311760006671	putative dimerization interface [polypeptide binding]; other site
1311760006672	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1311760006673	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1311760006674	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760006675	Walker A motif; other site
1311760006676	ATP binding site [chemical binding]; other site
1311760006677	Walker B motif; other site
1311760006678	arginine finger; other site
1311760006679	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1311760006680	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1311760006681	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1311760006682	catalytic motif [active]
1311760006683	Zn binding site [ion binding]; other site
1311760006684	RibD C-terminal domain; Region: RibD_C; cl17279
1311760006685	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1311760006686	Lumazine binding domain; Region: Lum_binding; pfam00677
1311760006687	Lumazine binding domain; Region: Lum_binding; pfam00677
1311760006688	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1311760006689	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1311760006690	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1311760006691	dimerization interface [polypeptide binding]; other site
1311760006692	active site
1311760006693	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1311760006694	homopentamer interface [polypeptide binding]; other site
1311760006695	active site
1311760006696	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1311760006697	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1311760006698	putative active site [active]
1311760006699	catalytic triad [active]
1311760006700	putative dimer interface [polypeptide binding]; other site
1311760006701	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
1311760006702	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1311760006703	Transporter associated domain; Region: CorC_HlyC; smart01091
1311760006704	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
1311760006705	hypothetical protein; Provisional; Region: PRK03641
1311760006706	polysaccharide export protein Wza; Provisional; Region: PRK15078
1311760006707	methionine aminopeptidase; Provisional; Region: PLN03158
1311760006708	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1311760006709	endonuclease IV; Provisional; Region: PRK01060
1311760006710	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1311760006711	AP (apurinic/apyrimidinic) site pocket; other site
1311760006712	DNA interaction; other site
1311760006713	Metal-binding active site; metal-binding site
1311760006714	NlpC/P60 family; Region: NLPC_P60; pfam00877
1311760006715	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
1311760006716	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1311760006717	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1311760006718	ligand binding site [chemical binding]; other site
1311760006719	active site
1311760006720	UGI interface [polypeptide binding]; other site
1311760006721	catalytic site [active]
1311760006722	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1311760006723	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1311760006724	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1311760006725	Peptidase S8 family domain in Autotransporter serine proteases; Region: Peptidases_S8_Autotransporter_serine_protease_like; cd04848
1311760006726	catalytic triad [active]
1311760006727	putative active site [active]
1311760006728	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1311760006729	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1311760006730	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1311760006731	ATP binding site [chemical binding]; other site
1311760006732	putative Mg++ binding site [ion binding]; other site
1311760006733	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1311760006734	nucleotide binding region [chemical binding]; other site
1311760006735	ATP-binding site [chemical binding]; other site
1311760006736	Helicase associated domain (HA2); Region: HA2; pfam04408
1311760006737	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1311760006738	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1311760006739	Predicted membrane protein [Function unknown]; Region: COG2707
1311760006740	GrpE; Region: GrpE; pfam01025
1311760006741	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1311760006742	dimer interface [polypeptide binding]; other site
1311760006743	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1311760006744	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1311760006745	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1311760006746	multidrug efflux protein; Reviewed; Region: PRK01766
1311760006747	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1311760006748	cation binding site [ion binding]; other site
1311760006749	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1311760006750	Part of AAA domain; Region: AAA_19; pfam13245
1311760006751	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1311760006752	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1311760006753	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1311760006754	aminopeptidase B; Provisional; Region: PRK05015
1311760006755	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1311760006756	interface (dimer of trimers) [polypeptide binding]; other site
1311760006757	Substrate-binding/catalytic site; other site
1311760006758	Zn-binding sites [ion binding]; other site
1311760006759	Predicted secreted acid phosphatase [General function prediction only]; Region: COG2503
1311760006760	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1311760006761	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1311760006762	HlyD family secretion protein; Region: HlyD_3; pfam13437
1311760006763	putative hydrolase; Provisional; Region: PRK10976
1311760006764	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760006765	active site
1311760006766	motif I; other site
1311760006767	motif II; other site
1311760006768	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1311760006769	2-isopropylmalate synthase; Validated; Region: PRK00915
1311760006770	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1311760006771	active site
1311760006772	catalytic residues [active]
1311760006773	metal binding site [ion binding]; metal-binding site
1311760006774	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1311760006775	RNA polymerase sigma factor AlgU; Provisional; Region: algU; PRK11923
1311760006776	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1311760006777	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1311760006778	DNA binding residues [nucleotide binding]
1311760006779	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseA; COG3073
1311760006780	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1311760006781	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1311760006782	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1311760006783	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1311760006784	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
1311760006785	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1311760006786	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1311760006787	acyl-activating enzyme (AAE) consensus motif; other site
1311760006788	putative AMP binding site [chemical binding]; other site
1311760006789	putative active site [active]
1311760006790	putative CoA binding site [chemical binding]; other site
1311760006791	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760006792	active site
1311760006793	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1311760006794	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006795	S-adenosylmethionine binding site [chemical binding]; other site
1311760006796	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1311760006797	SurA N-terminal domain; Region: SurA_N; pfam09312
1311760006798	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1311760006799	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1311760006800	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760006801	active site
1311760006802	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1311760006803	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1311760006804	putative ribose interaction site [chemical binding]; other site
1311760006805	putative ADP binding site [chemical binding]; other site
1311760006806	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1311760006807	active site
1311760006808	nucleotide binding site [chemical binding]; other site
1311760006809	HIGH motif; other site
1311760006810	KMSKS motif; other site
1311760006811	GTP-binding protein Der; Reviewed; Region: PRK00093
1311760006812	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1311760006813	G1 box; other site
1311760006814	GTP/Mg2+ binding site [chemical binding]; other site
1311760006815	Switch I region; other site
1311760006816	G2 box; other site
1311760006817	Switch II region; other site
1311760006818	G3 box; other site
1311760006819	G4 box; other site
1311760006820	G5 box; other site
1311760006821	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1311760006822	G1 box; other site
1311760006823	GTP/Mg2+ binding site [chemical binding]; other site
1311760006824	Switch I region; other site
1311760006825	G2 box; other site
1311760006826	G3 box; other site
1311760006827	Switch II region; other site
1311760006828	G4 box; other site
1311760006829	G5 box; other site
1311760006830	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1311760006831	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1311760006832	tRNA; other site
1311760006833	putative tRNA binding site [nucleotide binding]; other site
1311760006834	putative NADP binding site [chemical binding]; other site
1311760006835	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1311760006836	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1311760006837	HD domain; Region: HD_4; pfam13328
1311760006838	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1311760006839	synthetase active site [active]
1311760006840	NTP binding site [chemical binding]; other site
1311760006841	metal binding site [ion binding]; metal-binding site
1311760006842	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1311760006843	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1311760006844	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1311760006845	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1311760006846	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1311760006847	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1311760006848	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1311760006849	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
1311760006850	L-aspartate oxidase; Provisional; Region: PRK06175
1311760006851	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1311760006852	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760006853	Walker A/P-loop; other site
1311760006854	ATP binding site [chemical binding]; other site
1311760006855	Q-loop/lid; other site
1311760006856	ABC transporter signature motif; other site
1311760006857	Walker B; other site
1311760006858	D-loop; other site
1311760006859	H-loop/switch region; other site
1311760006860	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1311760006861	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1311760006862	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1311760006863	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760006864	dimer interface [polypeptide binding]; other site
1311760006865	conserved gate region; other site
1311760006866	putative PBP binding loops; other site
1311760006867	ABC-ATPase subunit interface; other site
1311760006868	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1311760006869	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760006870	Walker A/P-loop; other site
1311760006871	ATP binding site [chemical binding]; other site
1311760006872	Q-loop/lid; other site
1311760006873	ABC transporter signature motif; other site
1311760006874	Walker B; other site
1311760006875	D-loop; other site
1311760006876	H-loop/switch region; other site
1311760006877	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1311760006878	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1311760006879	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1311760006880	dimer interface [polypeptide binding]; other site
1311760006881	conserved gate region; other site
1311760006882	putative PBP binding loops; other site
1311760006883	ABC-ATPase subunit interface; other site
1311760006884	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1311760006885	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1311760006886	HemN family oxidoreductase; Provisional; Region: PRK05660
1311760006887	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760006888	FeS/SAM binding site; other site
1311760006889	HemN C-terminal domain; Region: HemN_C; pfam06969
1311760006890	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1311760006891	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1311760006892	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1311760006893	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1311760006894	catalytic triad [active]
1311760006895	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1311760006896	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1311760006897	active site
1311760006898	motif I; other site
1311760006899	motif II; other site
1311760006900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1311760006901	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1311760006902	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1311760006903	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1311760006904	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1311760006905	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1311760006906	putative active site [active]
1311760006907	HemK family putative methylases; Region: hemK_fam; TIGR00536
1311760006908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006909	S-adenosylmethionine binding site [chemical binding]; other site
1311760006910	hypothetical protein; Provisional; Region: PRK04946
1311760006911	Smr domain; Region: Smr; pfam01713
1311760006912	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1311760006913	putative deacylase active site [active]
1311760006914	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1311760006915	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1311760006916	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1311760006917	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1311760006918	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1311760006919	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760006920	Integrase core domain; Region: rve; pfam00665
1311760006921	Integrase core domain; Region: rve_3; pfam13683
1311760006922	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1311760006923	AAA domain; Region: AAA_31; pfam13614
1311760006924	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1311760006925	P-loop; other site
1311760006926	Magnesium ion binding site [ion binding]; other site
1311760006927	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1311760006928	Magnesium ion binding site [ion binding]; other site
1311760006929	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
1311760006930	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1311760006931	catalytic residue [active]
1311760006932	TraU protein; Region: TraU; cl06067
1311760006933	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
1311760006934	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1311760006935	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760006936	Walker A/P-loop; other site
1311760006937	ATP binding site [chemical binding]; other site
1311760006938	Q-loop/lid; other site
1311760006939	ABC transporter signature motif; other site
1311760006940	Walker B; other site
1311760006941	D-loop; other site
1311760006942	H-loop/switch region; other site
1311760006943	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1311760006944	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1311760006945	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1311760006946	Walker A/P-loop; other site
1311760006947	ATP binding site [chemical binding]; other site
1311760006948	Q-loop/lid; other site
1311760006949	ABC transporter signature motif; other site
1311760006950	Walker B; other site
1311760006951	D-loop; other site
1311760006952	H-loop/switch region; other site
1311760006953	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1311760006954	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1311760006955	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1311760006956	active site
1311760006957	zinc binding site [ion binding]; other site
1311760006958	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1311760006959	AAA domain; Region: AAA_26; pfam13500
1311760006960	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1311760006961	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760006962	S-adenosylmethionine binding site [chemical binding]; other site
1311760006963	Protein of unknown function (DUF452); Region: DUF452; pfam04301
1311760006964	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1311760006965	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1311760006966	substrate-cofactor binding pocket; other site
1311760006967	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760006968	catalytic residue [active]
1311760006969	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06173
1311760006970	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1311760006971	inhibitor-cofactor binding pocket; inhibition site
1311760006972	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1311760006973	catalytic residue [active]
1311760006974	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1311760006975	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1311760006976	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1311760006977	gamma-glutamyl kinase; Provisional; Region: PRK05429
1311760006978	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1311760006979	nucleotide binding site [chemical binding]; other site
1311760006980	homotetrameric interface [polypeptide binding]; other site
1311760006981	putative phosphate binding site [ion binding]; other site
1311760006982	putative allosteric binding site; other site
1311760006983	PUA domain; Region: PUA; pfam01472
1311760006984	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1311760006985	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1311760006986	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
1311760006987	N-terminal domain of PARMER_03128; Region: PARMER_03128_N; cd12106
1311760006988	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817
1311760006989	Baseplate J-like protein; Region: Baseplate_J; cl01294
1311760006990	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1311760006991	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1311760006992	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1311760006993	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1311760006994	Phage Tail Protein X; Region: Phage_tail_X; cl02088
1311760006995	Phage P2 GpU; Region: Phage_P2_GpU; cl01391
1311760006996	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
1311760006997	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
1311760006998	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
1311760006999	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
1311760007000	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760007001	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
1311760007002	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
1311760007003	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1311760007004	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1311760007005	Predicted transcriptional regulator [Transcription]; Region: COG2932
1311760007006	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1311760007007	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1311760007008	Catalytic site [active]
1311760007009	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1311760007010	Putative helicase; Region: TraI_2; pfam07514
1311760007011	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1311760007012	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
1311760007013	Winged helix-turn helix; Region: HTH_29; pfam13551
1311760007014	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549
1311760007015	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1311760007016	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1311760007017	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1311760007018	Putative helicase; Region: TraI_2; pfam07514
1311760007019	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1311760007020	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1311760007021	active site
1311760007022	catalytic residues [active]
1311760007023	DNA binding site [nucleotide binding]
1311760007024	Int/Topo IB signature motif; other site
1311760007025	ThiF family; Region: ThiF; pfam00899
1311760007026	ATP binding site [chemical binding]; other site
1311760007027	substrate interface [chemical binding]; other site
1311760007028	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1311760007029	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1311760007030	Walker A/P-loop; other site
1311760007031	ATP binding site [chemical binding]; other site
1311760007032	Q-loop/lid; other site
1311760007033	ABC transporter signature motif; other site
1311760007034	Walker B; other site
1311760007035	D-loop; other site
1311760007036	H-loop/switch region; other site
1311760007037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1311760007038	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1311760007039	putative substrate translocation pore; other site
1311760007040	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1311760007041	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1311760007042	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1311760007043	DNA binding site [nucleotide binding]
1311760007044	active site
1311760007045	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1311760007046	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1311760007047	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
1311760007048	Rrf2 family protein; Region: rrf2_super; TIGR00738
1311760007049	cysteine desulfurase; Provisional; Region: PRK14012
1311760007050	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1311760007051	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1311760007052	catalytic residue [active]
1311760007053	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1311760007054	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1311760007055	trimerization site [polypeptide binding]; other site
1311760007056	active site
1311760007057	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1311760007058	co-chaperone HscB; Provisional; Region: hscB; PRK01773
1311760007059	DnaJ domain; Region: DnaJ; pfam00226
1311760007060	HSP70 interaction site [polypeptide binding]; other site
1311760007061	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1311760007062	Protein of unknown function DUF2625; Region: DUF2625; pfam10946
1311760007063	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1311760007064	putative active site [active]
1311760007065	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1311760007066	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1311760007067	nucleotide binding site [chemical binding]; other site
1311760007068	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1311760007069	SBD interface [polypeptide binding]; other site
1311760007070	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1311760007071	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1311760007072	catalytic loop [active]
1311760007073	iron binding site [ion binding]; other site
1311760007074	Iron-sulphur cluster assembly; Region: Fe-S_assembly; cl01123
1311760007075	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1311760007076	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1311760007077	gating phenylalanine in ion channel; other site
1311760007078	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1311760007079	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1311760007080	active site
1311760007081	NTP binding site [chemical binding]; other site
1311760007082	metal binding triad [ion binding]; metal-binding site
1311760007083	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1311760007084	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1311760007085	Zn2+ binding site [ion binding]; other site
1311760007086	Mg2+ binding site [ion binding]; other site
1311760007087	endonuclease III; Provisional; Region: PRK10702
1311760007088	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1311760007089	minor groove reading motif; other site
1311760007090	helix-hairpin-helix signature motif; other site
1311760007091	substrate binding pocket [chemical binding]; other site
1311760007092	active site
1311760007093	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1311760007094	hypothetical protein; Provisional; Region: PRK10621
1311760007095	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1311760007096	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1311760007097	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1311760007098	folate binding site [chemical binding]; other site
1311760007099	NADP+ binding site [chemical binding]; other site
1311760007100	DNA repair protein RadA; Provisional; Region: PRK11823
1311760007101	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1311760007102	Walker A motif/ATP binding site; other site
1311760007103	ATP binding site [chemical binding]; other site
1311760007104	Walker B motif; other site
1311760007105	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1311760007106	putative major pilin subunit; Provisional; Region: PRK10574
1311760007107	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1311760007108	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1311760007109	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1311760007110	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1311760007111	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1311760007112	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1311760007113	CoA-binding site [chemical binding]; other site
1311760007114	ATP-binding [chemical binding]; other site
1311760007115	Domain of unknown function (DUF329); Region: DUF329; pfam03884
1311760007116	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1311760007117	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1311760007118	Lipopolysaccharide-assembly; Region: LptE; cl01125
1311760007119	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1311760007120	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1311760007121	HIGH motif; other site
1311760007122	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1311760007123	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1311760007124	active site
1311760007125	KMSKS motif; other site
1311760007126	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1311760007127	tRNA binding surface [nucleotide binding]; other site
1311760007128	seryl-tRNA synthetase; Provisional; Region: PRK05431
1311760007129	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1311760007130	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1311760007131	dimer interface [polypeptide binding]; other site
1311760007132	active site
1311760007133	motif 1; other site
1311760007134	motif 2; other site
1311760007135	motif 3; other site
1311760007136	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1311760007137	SmpB-tmRNA interface; other site
1311760007138	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1311760007139	salt bridge; other site
1311760007140	non-specific DNA binding site [nucleotide binding]; other site
1311760007141	sequence-specific DNA binding site [nucleotide binding]; other site
1311760007142	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1311760007143	YcjX-like family, DUF463; Region: DUF463; pfam04317
1311760007144	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1311760007145	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1311760007146	putative active site [active]
1311760007147	putative metal binding residues [ion binding]; other site
1311760007148	signature motif; other site
1311760007149	putative triphosphate binding site [ion binding]; other site
1311760007150	hypothetical protein; Provisional; Region: PRK05114
1311760007151	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1311760007152	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1311760007153	probable active site [active]
1311760007154	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1311760007155	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1311760007156	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1311760007157	active site
1311760007158	ribulose/triose binding site [chemical binding]; other site
1311760007159	phosphate binding site [ion binding]; other site
1311760007160	substrate (anthranilate) binding pocket [chemical binding]; other site
1311760007161	product (indole) binding pocket [chemical binding]; other site
1311760007162	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1311760007163	active site
1311760007164	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1311760007165	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1311760007166	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1311760007167	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1311760007168	active site
1311760007169	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1311760007170	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1311760007171	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1311760007172	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1311760007173	trimer interface [polypeptide binding]; other site
1311760007174	active site
1311760007175	UDP-GlcNAc binding site [chemical binding]; other site
1311760007176	lipid binding site [chemical binding]; lipid-binding site
1311760007177	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1311760007178	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1311760007179	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760007180	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760007181	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760007182	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760007183	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1311760007184	Surface antigen; Region: Bac_surface_Ag; pfam01103
1311760007185	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1311760007186	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1311760007187	active site
1311760007188	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1311760007189	protein binding site [polypeptide binding]; other site
1311760007190	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1311760007191	protein binding site [polypeptide binding]; other site
1311760007192	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1311760007193	putative substrate binding region [chemical binding]; other site
1311760007194	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1311760007195	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1311760007196	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1311760007197	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1311760007198	catalytic residue [active]
1311760007199	putative FPP diphosphate  binding site; other site
1311760007200	putative FPP binding hydrophobic cleft; other site
1311760007201	dimer interface [polypeptide binding]; other site
1311760007202	putative IPP diphosphate binding site; other site
1311760007203	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1311760007204	biotin synthase; Region: bioB; TIGR00433
1311760007205	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1311760007206	FeS/SAM binding site; other site
1311760007207	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1311760007208	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1311760007209	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1311760007210	active site
1311760007211	substrate-binding site [chemical binding]; other site
1311760007212	metal-binding site [ion binding]
1311760007213	ATP binding site [chemical binding]; other site
1311760007214	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1311760007215	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1311760007216	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1311760007217	substrate binding site; other site
1311760007218	dimer interface; other site
1311760007219	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1311760007220	homotrimer interaction site [polypeptide binding]; other site
1311760007221	zinc binding site [ion binding]; other site
1311760007222	CDP-binding sites; other site
1311760007223	Repair protein; Region: Repair_PSII; pfam04536
1311760007224	Repair protein; Region: Repair_PSII; cl01535
1311760007225	LemA family; Region: LemA; pfam04011
1311760007226	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1311760007227	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1311760007228	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1311760007229	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1311760007230	active site
1311760007231	P-loop; other site
1311760007232	phosphorylation site [posttranslational modification]
1311760007233	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
1311760007234	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1311760007235	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1311760007236	putative substrate binding site [chemical binding]; other site
1311760007237	putative ATP binding site [chemical binding]; other site
1311760007238	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK13779
1311760007239	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1311760007240	active site
1311760007241	phosphorylation site [posttranslational modification]
1311760007242	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1311760007243	dimerization domain swap beta strand [polypeptide binding]; other site
1311760007244	regulatory protein interface [polypeptide binding]; other site
1311760007245	active site
1311760007246	regulatory phosphorylation site [posttranslational modification]; other site
1311760007247	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1311760007248	dimerization domain swap beta strand [polypeptide binding]; other site
1311760007249	regulatory protein interface [polypeptide binding]; other site
1311760007250	active site
1311760007251	regulatory phosphorylation site [posttranslational modification]; other site
1311760007252	glycogen branching enzyme; Provisional; Region: PRK05402
1311760007253	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1311760007254	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1311760007255	active site
1311760007256	catalytic site [active]
1311760007257	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1311760007258	glycogen debranching enzyme; Provisional; Region: PRK03705
1311760007259	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1311760007260	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1311760007261	active site
1311760007262	catalytic site [active]
1311760007263	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1311760007264	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1311760007265	ligand binding site; other site
1311760007266	oligomer interface; other site
1311760007267	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1311760007268	dimer interface [polypeptide binding]; other site
1311760007269	N-terminal domain interface [polypeptide binding]; other site
1311760007270	sulfate 1 binding site; other site
1311760007271	glycogen synthase; Provisional; Region: glgA; PRK00654
1311760007272	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1311760007273	ADP-binding pocket [chemical binding]; other site
1311760007274	homodimer interface [polypeptide binding]; other site
1311760007275	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1311760007276	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1311760007277	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1311760007278	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1311760007279	ligand binding site [chemical binding]; other site
1311760007280	homodimer interface [polypeptide binding]; other site
1311760007281	NAD(P) binding site [chemical binding]; other site
1311760007282	trimer interface B [polypeptide binding]; other site
1311760007283	trimer interface A [polypeptide binding]; other site
1311760007284	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1311760007285	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1311760007286	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1311760007287	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1311760007288	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1311760007289	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1311760007290	putative dimerization interface [polypeptide binding]; other site
1311760007291	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1311760007292	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1311760007293	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1311760007294	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1311760007295	Predicted phage phi-C31 gp36 major capsid-like protein [General function prediction only]; Region: COG4653
1311760007296	Phage capsid family; Region: Phage_capsid; pfam05065
1311760007297	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1311760007298	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1311760007299	integrase; Provisional; Region: PRK09692
1311760007300	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1311760007301	active site
1311760007302	Int/Topo IB signature motif; other site
1311760007303	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1311760007304	DNA topoisomerase III; Provisional; Region: PRK07726
1311760007305	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1311760007306	active site
1311760007307	putative interdomain interaction site [polypeptide binding]; other site
1311760007308	putative metal-binding site [ion binding]; other site
1311760007309	putative nucleotide binding site [chemical binding]; other site
1311760007310	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1311760007311	domain I; other site
1311760007312	DNA binding groove [nucleotide binding]
1311760007313	phosphate binding site [ion binding]; other site
1311760007314	domain II; other site
1311760007315	domain III; other site
1311760007316	nucleotide binding site [chemical binding]; other site
1311760007317	catalytic site [active]
1311760007318	domain IV; other site
1311760007319	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1311760007320	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1311760007321	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1311760007322	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1311760007323	Tetramer interface [polypeptide binding]; other site
1311760007324	active site
1311760007325	FMN-binding site [chemical binding]; other site
1311760007326	hypothetical protein; Provisional; Region: PRK11281
1311760007327	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1311760007328	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1311760007329	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1311760007330	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1311760007331	acyl-activating enzyme (AAE) consensus motif; other site
1311760007332	putative AMP binding site [chemical binding]; other site
1311760007333	putative active site [active]
1311760007334	putative CoA binding site [chemical binding]; other site
1311760007335	SeqA protein; Region: SeqA; pfam03925
1311760007336	acyl-CoA esterase; Provisional; Region: PRK10673
1311760007337	PGAP1-like protein; Region: PGAP1; pfam07819
1311760007338	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1311760007339	S-adenosylmethionine binding site [chemical binding]; other site
1311760007340	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1311760007341	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1311760007342	DNA binding site [nucleotide binding]
1311760007343	domain linker motif; other site
1311760007344	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1311760007345	dimerization interface [polypeptide binding]; other site
1311760007346	ligand binding site [chemical binding]; other site
1311760007347	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1311760007348	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1311760007349	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1311760007350	trimer interface [polypeptide binding]; other site
1311760007351	active site
1311760007352	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1311760007353	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1311760007354	Sugar specificity; other site
1311760007355	Pyrimidine base specificity; other site
1311760007356	ATP-binding site [chemical binding]; other site
1311760007357	Lysine efflux permease [General function prediction only]; Region: COG1279
1311760007358	rod shape-determining protein MreB; Provisional; Region: PRK13927
1311760007359	MreB and similar proteins; Region: MreB_like; cd10225
1311760007360	nucleotide binding site [chemical binding]; other site
1311760007361	Mg binding site [ion binding]; other site
1311760007362	putative protofilament interaction site [polypeptide binding]; other site
1311760007363	RodZ interaction site [polypeptide binding]; other site
1311760007364	rod shape-determining protein MreC; Provisional; Region: PRK13922
1311760007365	rod shape-determining protein MreC; Region: MreC; pfam04085
1311760007366	rod shape-determining protein MreD; Region: MreD; cl01087
1311760007367	recombination factor protein RarA; Reviewed; Region: PRK13342
1311760007368	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1311760007369	Walker A motif; other site
1311760007370	ATP binding site [chemical binding]; other site
1311760007371	Walker B motif; other site
1311760007372	arginine finger; other site
1311760007373	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1311760007374	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1311760007375	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1311760007376	ABC-ATPase subunit  interface; other site
1311760007377	dimer interface [polypeptide binding]; other site
1311760007378	putative PBP binding regions; other site
1311760007379	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1311760007380	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1311760007381	putative active site [active]
1311760007382	putative dimer interface [polypeptide binding]; other site
1311760007383	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1311760007384	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1311760007385	substrate binding pocket [chemical binding]; other site
1311760007386	chain length determination region; other site
1311760007387	substrate-Mg2+ binding site; other site
1311760007388	catalytic residues [active]
1311760007389	aspartate-rich region 1; other site
1311760007390	active site lid residues [active]
1311760007391	aspartate-rich region 2; other site
1311760007392	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1311760007393	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1311760007394	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1311760007395	MOSC domain; Region: MOSC; pfam03473
1311760007396	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1311760007397	Sulfatase; Region: Sulfatase; pfam00884
1311760007398	fructokinase; Reviewed; Region: PRK09557
1311760007399	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1311760007400	nucleotide binding site [chemical binding]; other site
1311760007401	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1311760007402	active site
1311760007403	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1311760007404	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1311760007405	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1311760007406	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1311760007407	putative metal binding site; other site
1311760007408	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1311760007409	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1311760007410	putative active site [active]
1311760007411	argininosuccinate synthase; Validated; Region: PRK05370
1311760007412	argininosuccinate synthase; Provisional; Region: PRK13820
1311760007413	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1311760007414	RNA/DNA hybrid binding site [nucleotide binding]; other site
1311760007415	active site
1311760007416	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1311760007417	Colicin V production protein; Region: Colicin_V; cl00567
1311760007418	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1311760007419	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1311760007420	active site
1311760007421	tetramer interface [polypeptide binding]; other site
1311760007422	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1311760007423	active site
1311760007424	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1311760007425	MltA specific insert domain; Region: MltA; smart00925
1311760007426	3D domain; Region: 3D; pfam06725
1311760007427	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1311760007428	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1311760007429	generic binding surface II; other site
1311760007430	generic binding surface I; other site
1311760007431	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1311760007432	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1311760007433	P-loop; other site
1311760007434	Magnesium ion binding site [ion binding]; other site
1311760007435	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1311760007436	replicative DNA helicase; Region: DnaB; TIGR00665
1311760007437	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1311760007438	Walker A motif; other site
1311760007439	ATP binding site [chemical binding]; other site
1311760007440	Walker B motif; other site
1311760007441	DNA binding loops [nucleotide binding]
1311760007442	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
1311760007443	ParB-like nuclease domain; Region: ParBc; pfam02195
1311760007444	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
1311760007445	Domain of unknown function (DUF1845); Region: DUF1845; pfam08900
1311760007446	Protein of unknown function (DUF3158); Region: DUF3158; pfam11358
1311760007447	DNA topoisomerase III; Provisional; Region: PRK07726
1311760007448	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1311760007449	active site
1311760007450	putative interdomain interaction site [polypeptide binding]; other site
1311760007451	putative metal-binding site [ion binding]; other site
1311760007452	putative nucleotide binding site [chemical binding]; other site
1311760007453	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1311760007454	domain I; other site
1311760007455	DNA binding groove [nucleotide binding]
1311760007456	phosphate binding site [ion binding]; other site
1311760007457	domain II; other site
1311760007458	domain III; other site
1311760007459	nucleotide binding site [chemical binding]; other site
1311760007460	catalytic site [active]
1311760007461	domain IV; other site
1311760007462	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1311760007463	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
1311760007464	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
1311760007465	PcfJ-like protein; Region: PcfJ; pfam14284
1311760007466	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
1311760007467	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1311760007468	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1311760007469	catalytic residue [active]
1311760007470	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
1311760007471	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
1311760007472	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
1311760007473	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
1311760007474	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
1311760007475	Protein of unknown function (DUF2976); Region: DUF2976; pfam11190
1311760007476	Protein of unknown function (DUF3487); Region: DUF3487; pfam11990
1311760007477	Protein of unknown function (DUF2895); Region: DUF2895; pfam11444
1311760007478	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
1311760007479	TraK protein; Region: TraK; pfam06586
1311760007480	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
1311760007481	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
1311760007482	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
1311760007483	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1311760007484	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
1311760007485	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
1311760007486	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
1311760007487	Protein of unknown function (DUF1525); Region: DUF1525; pfam07511