-- dump date 20140619_144206 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002418899.1 218528083 7114060 359..625 1 NC_011757.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 625 rpsT 7114060 rpsT Methylobacterium extorquens CM4 30S ribosomal protein S20 YP_002418899.1 359 D 440085 CDS YP_002418900.1 218528084 7114061 1438..2943 1 NC_011757.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 2943 dnaA 7114061 dnaA Methylobacterium extorquens CM4 chromosomal replication initiation protein YP_002418900.1 1438 D 440085 CDS YP_002418901.1 218528085 7114062 3266..4387 1 NC_011757.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4387 7114062 Mchl_0003 Methylobacterium extorquens CM4 DNA polymerase III subunit beta YP_002418901.1 3266 D 440085 CDS YP_002418902.1 218528086 7114063 4428..5585 1 NC_011757.1 KEGG: mex:Mext_0003 DNA replication and repair protein RecF; TIGRFAM: DNA replication and repair protein RecF; PFAM: SMC domain protein; SMART: ATPase AAA; DNA replication and repair protein RecF 5585 7114063 Mchl_0004 Methylobacterium extorquens CM4 DNA replication and repair protein RecF YP_002418902.1 4428 D 440085 CDS YP_002418903.1 218528087 7114064 5593..6204 1 NC_011757.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: mpo:Mpop_0005 lysine exporter protein (LysE/YggA); lysine exporter LysE/YggA 6204 7114064 Mchl_0005 Methylobacterium extorquens CM4 lysine exporter LysE/YggA YP_002418903.1 5593 D 440085 CDS YP_002418904.1 218528088 7114065 complement(6208..6432) 1 NC_011757.1 KEGG: mex:Mext_0005 transcription factor; hypothetical protein 6432 7114065 Mchl_0006 Methylobacterium extorquens CM4 hypothetical protein YP_002418904.1 6208 R 440085 CDS YP_002418905.1 218528089 7114066 6543..8390 1 NC_011757.1 KEGG: mex:Mext_0006 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase; HRDC domain protein; DEAD/DEAH box helicase; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; ATP-dependent DNA helicase RecQ 8390 7114066 Mchl_0007 Methylobacterium extorquens CM4 ATP-dependent DNA helicase RecQ YP_002418905.1 6543 D 440085 CDS YP_002418906.1 218528090 7114067 complement(8448..8786) 1 NC_011757.1 KEGG: mex:Mext_0007 hypothetical protein; hypothetical protein 8786 7114067 Mchl_0008 Methylobacterium extorquens CM4 hypothetical protein YP_002418906.1 8448 R 440085 CDS YP_002418907.1 218528091 7114068 9102..9788 1 NC_011757.1 KEGG: mex:Mext_0008 hypothetical protein; hypothetical protein 9788 7114068 Mchl_0009 Methylobacterium extorquens CM4 hypothetical protein YP_002418907.1 9102 D 440085 CDS YP_002418908.1 218528092 7114069 9896..12097 1 NC_011757.1 KEGG: mex:Mext_0009 RecD/TraA family helicase; TIGRFAM: helicase, RecD/TraA family; SMART: DNA-binding protein; ATPase AAA; RecD/TraA family helicase 12097 7114069 Mchl_0010 Methylobacterium extorquens CM4 RecD/TraA family helicase YP_002418908.1 9896 D 440085 CDS YP_002418909.1 218528093 7114070 12241..13425 1 NC_011757.1 KEGG: mex:Mext_0010 hypothetical protein; hypothetical protein 13425 7114070 Mchl_0011 Methylobacterium extorquens CM4 hypothetical protein YP_002418909.1 12241 D 440085 CDS YP_002418910.1 218528094 7114071 13616..15841 1 NC_011757.1 KEGG: mex:Mext_0011 phosphoribosylformylglycinamidine synthase II; TIGRFAM: phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; phosphoribosylformylglycinamidine synthase II 15841 7114071 Mchl_0012 Methylobacterium extorquens CM4 phosphoribosylformylglycinamidine synthase II YP_002418910.1 13616 D 440085 CDS YP_002418911.1 218528095 7114072 15868..16104 1 NC_011757.1 PFAM: BolA family protein; KEGG: mex:Mext_0012 BolA family protein; BolA family protein 16104 7114072 Mchl_0013 Methylobacterium extorquens CM4 BolA family protein YP_002418911.1 15868 D 440085 CDS YP_002418912.1 218528096 7114073 16178..16513 1 NC_011757.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: mex:Mext_0013 glutaredoxin-like protein; glutaredoxin-like protein 16513 7114073 Mchl_0014 Methylobacterium extorquens CM4 glutaredoxin-like protein YP_002418912.1 16178 D 440085 CDS YP_002418913.1 218528097 7114074 16586..17488 1 NC_011757.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_0014 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 17488 7114074 Mchl_0015 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002418913.1 16586 D 440085 CDS YP_002418914.1 218528098 7114075 17597..18481 1 NC_011757.1 PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: mex:Mext_0015 SMP-30/gluconolaconase/LRE domain-containing protein; SMP-30/gluconolaconase/LRE domain-containing protein 18481 7114075 Mchl_0016 Methylobacterium extorquens CM4 SMP-30/gluconolaconase/LRE domain-containing protein YP_002418914.1 17597 D 440085 CDS YP_002418915.1 218528099 7114076 18667..18882 1 NC_011757.1 KEGG: mex:Mext_0016 hypothetical protein; hypothetical protein 18882 7114076 Mchl_0017 Methylobacterium extorquens CM4 hypothetical protein YP_002418915.1 18667 D 440085 CDS YP_002418916.1 218528100 7114077 complement(18910..19746) 1 NC_011757.1 KEGG: mex:Mext_0017 hypothetical protein; hypothetical protein 19746 7114077 Mchl_0018 Methylobacterium extorquens CM4 hypothetical protein YP_002418916.1 18910 R 440085 CDS YP_002418917.1 218528101 7114078 complement(20115..22160) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; KEGG: mex:Mext_0018 ATPase domain-containing protein; PAS/PAC sensor hybrid histidine kinase 22160 7114078 Mchl_0019 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002418917.1 20115 R 440085 CDS YP_002418918.1 218528102 7114079 complement(22160..23722) 1 NC_011757.1 KEGG: mex:Mext_0019 non-specific serine/threonine protein kinase; PFAM: Circadian clock protein KaiC central region; KaiA binding; SMART: ATPase AAA; circadian clock protein KaiC 23722 7114079 Mchl_0020 Methylobacterium extorquens CM4 circadian clock protein KaiC YP_002418918.1 22160 R 440085 CDS YP_002418919.1 218528103 7114080 24073..25278 1 NC_011757.1 KEGG: mex:Mext_0020 hypothetical protein; hypothetical protein 25278 7114080 Mchl_0021 Methylobacterium extorquens CM4 hypothetical protein YP_002418919.1 24073 D 440085 CDS YP_002418920.1 218528104 7114081 complement(25309..26307) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_0021 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 26307 7114081 Mchl_0022 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002418920.1 25309 R 440085 CDS YP_002418921.1 218528105 7114082 complement(26430..27122) 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_0022 GntR domain-containing protein; GntR family transcriptional regulator 27122 7114082 Mchl_0023 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002418921.1 26430 R 440085 CDS YP_002418922.1 218528106 7114084 27765..29411 1 NC_011757.1 TIGRFAM: malonate decarboxylase, subunit alpha; KEGG: mex:Mext_0024 malonate decarboxylase, subunit alpha; malonate decarboxylase subunit alpha 29411 7114084 Mchl_0025 Methylobacterium extorquens CM4 malonate decarboxylase subunit alpha YP_002418922.1 27765 D 440085 CDS YP_002418923.1 218528107 7114085 29419..29727 1 NC_011757.1 acyl carrier protein of malonate decarboxylase; malonate decarboxylase subunit delta 29727 7114085 Mchl_0026 Methylobacterium extorquens CM4 malonate decarboxylase subunit delta YP_002418923.1 29419 D 440085 CDS YP_002418924.1 218528108 7114086 29730..30662 1 NC_011757.1 The subunit beta catalyzes the decarboxylation of the malonyl moiety on coenzyme A; malonate decarboxylase subunit beta 30662 7114086 Mchl_0027 Methylobacterium extorquens CM4 malonate decarboxylase subunit beta YP_002418924.1 29730 D 440085 CDS YP_002418925.1 218528109 7114087 30649..31365 1 NC_011757.1 TIGRFAM: malonate decarboxylase, subunit gamma; PFAM: malonate decarboxylase subunit gamma; KEGG: mex:Mext_0027 malonate decarboxylase, subunit gamma; malonate decarboxylase subunit gamma 31365 7114087 Mchl_0028 Methylobacterium extorquens CM4 malonate decarboxylase subunit gamma YP_002418925.1 30649 D 440085 CDS YP_002418926.1 218528110 7114088 31358..32017 1 NC_011757.1 TIGRFAM: holo-ACP synthase, malonate decarboxylase-specific; KEGG: mex:Mext_0028 hypothetical protein; holo-ACP synthase, malonate decarboxylase-specific 32017 7114088 Mchl_0029 Methylobacterium extorquens CM4 holo-ACP synthase, malonate decarboxylase-specific YP_002418926.1 31358 D 440085 CDS YP_002418927.1 218528111 7114089 32014..32874 1 NC_011757.1 KEGG: mex:Mext_0029 triphosphoribosyl-dephospho-CoA synthase MdcB; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase MdcB; PFAM: triphosphoribosyl-dephospho-CoA protein; triphosphoribosyl-dephospho-CoA synthase MdcB 32874 7114089 Mchl_0030 Methylobacterium extorquens CM4 triphosphoribosyl-dephospho-CoA synthase MdcB YP_002418927.1 32014 D 440085 CDS YP_002418928.1 218528112 7114090 32871..33794 1 NC_011757.1 KEGG: mex:Mext_0030 acyl transferase domain-containing protein; acyl transferase domain-containing protein 33794 7114090 Mchl_0031 Methylobacterium extorquens CM4 acyl transferase domain-containing protein YP_002418928.1 32871 D 440085 CDS YP_002418929.1 218528113 7114092 complement(36407..37297) 1 NC_011757.1 KEGG: met:M446_1613 general secretion pathway protein K; general secretion pathway protein K 37297 7114092 Mchl_0033 Methylobacterium extorquens CM4 general secretion pathway protein K YP_002418929.1 36407 R 440085 CDS YP_002418930.1 218528114 7114096 complement(38737..39381) 1 NC_011757.1 PFAM: electron transporter SCO1/SenC; KEGG: met:M446_1393 electron transporter SCO1/SenC; electron transporter SCO1/SenC 39381 7114096 Mchl_0037 Methylobacterium extorquens CM4 electron transporter SCO1/SenC YP_002418930.1 38737 R 440085 CDS YP_002418931.1 218528115 7114097 complement(39489..39758) 1 NC_011757.1 KEGG: met:M446_1394 hypothetical protein; hypothetical protein 39758 7114097 Mchl_0038 Methylobacterium extorquens CM4 hypothetical protein YP_002418931.1 39489 R 440085 CDS YP_002418932.1 218528116 7114098 complement(39881..42883) 1 NC_011757.1 PFAM: ricin B lectin; hypothetical protein; Domain of unknown function DUF1929; KEGG: met:M446_1395 galactose oxidase; Galactose oxidase 42883 7114098 Mchl_0039 Methylobacterium extorquens CM4 Galactose oxidase YP_002418932.1 39881 R 440085 CDS YP_002418933.1 218528117 7114099 complement(43010..43741) 1 NC_011757.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: mpo:Mpop_0070 IstB domain protein ATP-binding protein; IstB domain-containing protein ATP-binding protein 43741 7114099 Mchl_0040 Methylobacterium extorquens CM4 IstB domain-containing protein ATP-binding protein YP_002418933.1 43010 R 440085 CDS YP_002418934.1 218528118 7114100 complement(43741..45246) 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mpo:Mpop_0069 integrase catalytic region; integrase catalytic subunit 45246 7114100 Mchl_0041 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002418934.1 43741 R 440085 CDS YP_002418935.1 218528119 7114102 complement(45544..47052) 1 NC_011757.1 PFAM: phospholipase D/transphosphatidylase; KEGG: mex:Mext_0106 phospholipase D/transphosphatidylase; phospholipase D/transphosphatidylase 47052 7114102 Mchl_0043 Methylobacterium extorquens CM4 phospholipase D/transphosphatidylase YP_002418935.1 45544 R 440085 CDS YP_002418936.1 218528120 7114103 47937..50369 1 NC_011757.1 KEGG: bxe:Bxe_A2619 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 50369 7114103 Mchl_0044 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002418936.1 47937 D 440085 CDS YP_002418937.1 218528121 7114106 complement(51179..51424) 1 NC_011757.1 KEGG: mex:Mext_0057 hypothetical protein; hypothetical protein 51424 7114106 Mchl_0047 Methylobacterium extorquens CM4 hypothetical protein YP_002418937.1 51179 R 440085 CDS YP_002418938.1 218528122 7114107 complement(51543..52610) 1 NC_011757.1 PFAM: peptidase M20; peptidase M42 family protein; KEGG: mex:Mext_0058 peptidase M42 family protein; peptidase M42 family protein 52610 7114107 Mchl_0048 Methylobacterium extorquens CM4 peptidase M42 family protein YP_002418938.1 51543 R 440085 CDS YP_002418939.1 218528123 7114108 complement(53376..54644) 1 NC_011757.1 PFAM: transposase mutator type; KEGG: mrd:Mrad2831_2616 transposase mutator type; transposase mutator type 54644 7114108 Mchl_0049 Methylobacterium extorquens CM4 transposase mutator type YP_002418939.1 53376 R 440085 CDS YP_002418940.1 218528124 7114109 55017..55289 1 NC_011757.1 KEGG: mrd:Mrad2831_5711 hypothetical protein; hypothetical protein 55289 7114109 Mchl_0050 Methylobacterium extorquens CM4 hypothetical protein YP_002418940.1 55017 D 440085 CDS YP_002418941.1 218528125 7114111 56359..56604 1 NC_011757.1 KEGG: mex:Mext_3809 hypothetical protein; hypothetical protein 56604 7114111 Mchl_0052 Methylobacterium extorquens CM4 hypothetical protein YP_002418941.1 56359 D 440085 CDS YP_002418942.1 218528126 7114112 complement(56766..57083) 1 NC_011757.1 KEGG: mex:Mext_1866 hypothetical protein; hypothetical protein 57083 7114112 Mchl_0053 Methylobacterium extorquens CM4 hypothetical protein YP_002418942.1 56766 R 440085 CDS YP_002418943.1 218528127 7113897 complement(57564..57809) 1 NC_011757.1 hypothetical protein 57809 7113897 Mchl_0055 Methylobacterium extorquens CM4 hypothetical protein YP_002418943.1 57564 R 440085 CDS YP_002418944.1 218528128 7113980 complement(58062..58226) 1 NC_011757.1 hypothetical protein 58226 7113980 Mchl_0057 Methylobacterium extorquens CM4 hypothetical protein YP_002418944.1 58062 R 440085 CDS YP_002418945.1 218528129 7113982 complement(59438..59674) 1 NC_011757.1 KEGG: mex:Mext_0782 hypothetical protein; hypothetical protein 59674 7113982 Mchl_0059 Methylobacterium extorquens CM4 hypothetical protein YP_002418945.1 59438 R 440085 CDS YP_002418946.1 218528130 7113983 complement(59671..60825) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: response regulator receiver; KEGG: mex:Mext_0783 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 60825 7113983 Mchl_0060 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002418946.1 59671 R 440085 CDS YP_002418947.1 218528131 7113984 61094..61807 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_0075 hypothetical protein; cyclic nucleotide-binding protein 61807 7113984 Mchl_0061 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002418947.1 61094 D 440085 CDS YP_002418948.1 218528132 7113985 61807..62067 1 NC_011757.1 KEGG: mex:Mext_0785 hypothetical protein; hypothetical protein 62067 7113985 Mchl_0062 Methylobacterium extorquens CM4 hypothetical protein YP_002418948.1 61807 D 440085 CDS YP_002418949.1 218528133 7113986 complement(62361..64874) 1 NC_011757.1 KEGG: mrd:Mrad2831_4387 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; multi-sensor hybrid histidine kinase 64874 7113986 Mchl_0063 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002418949.1 62361 R 440085 CDS YP_002418950.1 218528134 7113987 complement(65143..65886) 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mrd:Mrad2831_1051 methyltransferase type 11; type 11 methyltransferase 65886 7113987 Mchl_0064 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002418950.1 65143 R 440085 CDS YP_002418951.1 218528135 7113988 65962..66474 1 NC_011757.1 KEGG: mpo:Mpop_3826 hypothetical protein; hypothetical protein 66474 7113988 Mchl_0065 Methylobacterium extorquens CM4 hypothetical protein YP_002418951.1 65962 D 440085 CDS YP_002418952.1 218528136 7113989 complement(66523..66729) 1 NC_011757.1 KEGG: mpo:Mpop_4881 hypothetical protein; hypothetical protein 66729 7113989 Mchl_0066 Methylobacterium extorquens CM4 hypothetical protein YP_002418952.1 66523 R 440085 CDS YP_002418953.1 218528137 7113990 67354..67593 1 NC_011757.1 KEGG: hypothetical protein; hypothetical protein 67593 7113990 Mchl_0067 Methylobacterium extorquens CM4 hypothetical protein YP_002418953.1 67354 D 440085 CDS YP_002418954.1 218528138 7113991 complement(67612..67905) 1 NC_011757.1 KEGG: mex:Mext_0117 hypothetical protein; hypothetical protein 67905 7113991 Mchl_0068 Methylobacterium extorquens CM4 hypothetical protein YP_002418954.1 67612 R 440085 CDS YP_002418955.1 218528139 7113992 complement(68105..68266) 1 NC_011757.1 hypothetical protein 68266 7113992 Mchl_0069 Methylobacterium extorquens CM4 hypothetical protein YP_002418955.1 68105 R 440085 CDS YP_002418956.1 218528140 7113994 complement(69036..69449) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mpo:Mpop_0480 isochorismatase hydrolase; isochorismatase hydrolase 69449 7113994 Mchl_0070 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002418956.1 69036 R 440085 CDS YP_002418957.1 218528141 7113996 complement(70657..70860) 1 NC_011757.1 KEGG: mex:Mext_0146 hypothetical protein; hypothetical protein 70860 7113996 Mchl_0072 Methylobacterium extorquens CM4 hypothetical protein YP_002418957.1 70657 R 440085 CDS YP_002418958.1 218528142 7113997 complement(70992..71453) 1 NC_011757.1 KEGG: mex:Mext_0147 hypothetical protein; hypothetical protein 71453 7113997 Mchl_0073 Methylobacterium extorquens CM4 hypothetical protein YP_002418958.1 70992 R 440085 CDS YP_002418959.1 218528143 7113999 72890..73093 1 NC_011757.1 KEGG: gdi:GDI0123 hypothetical protein; hypothetical protein 73093 7113999 Mchl_0075 Methylobacterium extorquens CM4 hypothetical protein YP_002418959.1 72890 D 440085 CDS YP_002418960.1 218528144 7114000 73189..73758 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_0081 integrase family protein; integrase family protein 73758 7114000 Mchl_0076 Methylobacterium extorquens CM4 integrase family protein YP_002418960.1 73189 D 440085 CDS YP_002418961.1 218528145 7114001 complement(73800..74081) 1 NC_011757.1 KEGG: mex:Mext_0084 hypothetical protein; hypothetical protein 74081 7114001 Mchl_0077 Methylobacterium extorquens CM4 hypothetical protein YP_002418961.1 73800 R 440085 CDS YP_002418962.1 218528146 7114002 complement(74139..75338) 1 NC_011757.1 KEGG: mex:Mext_0085 hypothetical protein; hypothetical protein 75338 7114002 Mchl_0078 Methylobacterium extorquens CM4 hypothetical protein YP_002418962.1 74139 R 440085 CDS YP_002418963.1 218528147 7114003 75406..75591 1 NC_011757.1 KEGG: mex:Mext_0168 hypothetical protein; hypothetical protein 75591 7114003 Mchl_0079 Methylobacterium extorquens CM4 hypothetical protein YP_002418963.1 75406 D 440085 CDS YP_002418964.1 218528148 7114004 75596..76063 1 NC_011757.1 KEGG: mex:Mext_0169 hypothetical protein; hypothetical protein 76063 7114004 Mchl_0080 Methylobacterium extorquens CM4 hypothetical protein YP_002418964.1 75596 D 440085 CDS YP_002418965.1 218528149 7114005 76187..76762 1 NC_011757.1 KEGG: mex:Mext_0088 hypothetical protein; hypothetical protein 76762 7114005 Mchl_0081 Methylobacterium extorquens CM4 hypothetical protein YP_002418965.1 76187 D 440085 CDS YP_002418966.1 218528150 7114006 76824..77417 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_0170 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 77417 7114006 Mchl_0082 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002418966.1 76824 D 440085 CDS YP_002418967.1 218528151 7114007 77462..77770 1 NC_011757.1 hypothetical protein 77770 7114007 Mchl_0083 Methylobacterium extorquens CM4 hypothetical protein YP_002418967.1 77462 D 440085 CDS YP_002418968.1 218528152 7114008 complement(77828..78730) 1 NC_011757.1 PFAM: restriction endonuclease; KEGG: xcb:XC_3184 Mrr restriction endonuclease; restriction endonuclease 78730 7114008 Mchl_0084 Methylobacterium extorquens CM4 restriction endonuclease YP_002418968.1 77828 R 440085 CDS YP_002418969.1 218528153 7114009 complement(79024..80214) 1 NC_011757.1 KEGG: nha:Nham_4025 hypothetical protein; hypothetical protein 80214 7114009 Mchl_0085 Methylobacterium extorquens CM4 hypothetical protein YP_002418969.1 79024 R 440085 CDS YP_002418970.1 218528154 7114010 complement(80614..81936) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_0101 integrase family protein; integrase family protein 81936 7114010 Mchl_0086 Methylobacterium extorquens CM4 integrase family protein YP_002418970.1 80614 R 440085 CDS YP_002418971.1 218528155 7114011 complement(82275..83273) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_0102 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 83273 7114011 Mchl_0087 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002418971.1 82275 R 440085 CDS YP_002418972.1 218528156 7114012 83582..83803 1 NC_011757.1 KEGG: mex:Mext_0103 hypothetical protein; hypothetical protein 83803 7114012 Mchl_0088 Methylobacterium extorquens CM4 hypothetical protein YP_002418972.1 83582 D 440085 CDS YP_002418973.1 218528157 7114013 complement(84326..85264) 1 NC_011757.1 PFAM: homocysteine S-methyltransferase; KEGG: amr:AM1_0903 homocysteine S-methyltransferase; homocysteine S-methyltransferase 85264 7114013 Mchl_0089 Methylobacterium extorquens CM4 homocysteine S-methyltransferase YP_002418973.1 84326 R 440085 CDS YP_002418974.1 218528158 7114015 complement(85733..86107) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: met:M446_6212 response regulator receiver protein; response regulator receiver protein 86107 7114015 Mchl_0091 Methylobacterium extorquens CM4 response regulator receiver protein YP_002418974.1 85733 R 440085 CDS YP_002418975.1 218528159 7114017 join(86874..87215,87215..87817) 1 NC_011757.1 KEGG: met:M446_6905 insertion sequence transposase protein; transposase 87817 7114017 Mchl_0093 Methylobacterium extorquens CM4 transposase YP_002418975.1 86874 D 440085 CDS YP_002418976.1 218528160 7114018 complement(87837..88613) 1 NC_011757.1 KEGG: mpo:Mpop_2180 hypothetical protein; hypothetical protein 88613 7114018 Mchl_0094 Methylobacterium extorquens CM4 hypothetical protein YP_002418976.1 87837 R 440085 CDS YP_002418977.1 218528161 7114019 complement(88687..89049) 1 NC_011757.1 KEGG: mex:Mext_0493 hypothetical protein; hypothetical protein 89049 7114019 Mchl_0095 Methylobacterium extorquens CM4 hypothetical protein YP_002418977.1 88687 R 440085 CDS YP_002418978.1 218528162 7114020 89405..89905 1 NC_011757.1 KEGG: mex:Mext_0110 hypothetical protein; hypothetical protein 89905 7114020 Mchl_0096 Methylobacterium extorquens CM4 hypothetical protein YP_002418978.1 89405 D 440085 CDS YP_002418979.1 218528163 7114021 90422..91237 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_0489 UspA domain-containing protein; UspA domain-containing protein 91237 7114021 Mchl_0097 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002418979.1 90422 D 440085 CDS YP_002418980.1 218528164 7114022 complement(91299..91457) 1 NC_011757.1 KEGG: bxe:Bxe_B2278 hypothetical protein; hypothetical protein 91457 7114022 Mchl_0098 Methylobacterium extorquens CM4 hypothetical protein YP_002418980.1 91299 R 440085 CDS YP_002418981.1 218528165 7114023 complement(91562..91825) 1 NC_011757.1 KEGG: mex:Mext_0766 hypothetical protein; hypothetical protein 91825 7114023 Mchl_0099 Methylobacterium extorquens CM4 hypothetical protein YP_002418981.1 91562 R 440085 CDS YP_002418982.1 218528166 7114024 92145..92657 1 NC_011757.1 KEGG: mpo:Mpop_3826 hypothetical protein; hypothetical protein 92657 7114024 Mchl_0100 Methylobacterium extorquens CM4 hypothetical protein YP_002418982.1 92145 D 440085 CDS YP_002418983.1 218528167 7114025 complement(92706..92912) 1 NC_011757.1 KEGG: mpo:Mpop_4881 hypothetical protein; hypothetical protein 92912 7114025 Mchl_0101 Methylobacterium extorquens CM4 hypothetical protein YP_002418983.1 92706 R 440085 CDS YP_002418984.1 218528168 7114026 93537..93776 1 NC_011757.1 KEGG: hypothetical protein; hypothetical protein 93776 7114026 Mchl_0102 Methylobacterium extorquens CM4 hypothetical protein YP_002418984.1 93537 D 440085 CDS YP_002418985.1 218528169 7114028 complement(95019..95285) 1 NC_011757.1 KEGG: mex:Mext_2419 hypothetical protein; hypothetical protein 95285 7114028 Mchl_0103 Methylobacterium extorquens CM4 hypothetical protein YP_002418985.1 95019 R 440085 CDS YP_002418986.1 218528170 7114031 complement(96287..96439) 1 NC_011757.1 hypothetical protein 96439 7114031 Mchl_0106 Methylobacterium extorquens CM4 hypothetical protein YP_002418986.1 96287 R 440085 CDS YP_002418987.1 218528171 7114032 96893..97009 1 NC_011757.1 hypothetical protein 97009 7114032 Mchl_0107 Methylobacterium extorquens CM4 hypothetical protein YP_002418987.1 96893 D 440085 CDS YP_002418988.1 218528172 7114033 complement(97281..104309) 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; Animal haem peroxidase; KEGG: rpe:RPE_1007 heme peroxidase; heme peroxidase 104309 7114033 Mchl_0108 Methylobacterium extorquens CM4 heme peroxidase YP_002418988.1 97281 R 440085 CDS YP_002418989.1 218528173 7114034 104722..105057 1 NC_011757.1 KEGG: mrd:Mrad2831_3884 hypothetical protein; hypothetical protein 105057 7114034 Mchl_0109 Methylobacterium extorquens CM4 hypothetical protein YP_002418989.1 104722 D 440085 CDS YP_002418990.1 218528174 7114035 105054..105320 1 NC_011757.1 KEGG: mpo:Mpop_4259 hypothetical protein; hypothetical protein 105320 7114035 Mchl_0110 Methylobacterium extorquens CM4 hypothetical protein YP_002418990.1 105054 D 440085 CDS YP_002418991.1 218528175 7114038 106596..108290 1 NC_011757.1 PFAM: acyltransferase 3; KEGG: bid:Bind_1595 acyltransferase 3; acyltransferase 3 108290 7114038 Mchl_0113 Methylobacterium extorquens CM4 acyltransferase 3 YP_002418991.1 106596 D 440085 CDS YP_002418992.1 218528176 7114039 108484..108855 1 NC_011757.1 KEGG: mrd:Mrad2831_6451 hypothetical protein; hypothetical protein 108855 7114039 Mchl_0114 Methylobacterium extorquens CM4 hypothetical protein YP_002418992.1 108484 D 440085 CDS YP_002418993.1 218528177 7114040 109025..110029 1 NC_011757.1 PFAM: peptidase M23; KEGG: swi:Swit_4002 peptidase M23B; peptidase M23 110029 7114040 Mchl_0115 Methylobacterium extorquens CM4 peptidase M23 YP_002418993.1 109025 D 440085 CDS YP_002418994.1 218528178 7114041 complement(110042..111049) 1 NC_011757.1 KEGG: bce:BC4487 superfamily I DNA/RNA helicase; hypothetical protein 111049 7114041 Mchl_0116 Methylobacterium extorquens CM4 hypothetical protein YP_002418994.1 110042 R 440085 CDS YP_002418995.1 218528179 7114042 complement(111214..112536) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_0101 integrase family protein; integrase family protein 112536 7114042 Mchl_0117 Methylobacterium extorquens CM4 integrase family protein YP_002418995.1 111214 R 440085 CDS YP_002418996.1 218528180 7114044 complement(112922..114163) 1 NC_011757.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 114163 7114044 Mchl_0118 Methylobacterium extorquens CM4 tryptophan synthase subunit beta YP_002418996.1 112922 R 440085 CDS YP_002418997.1 218528181 7114045 complement(114286..114933) 1 NC_011757.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mex:Mext_0177 phosphoribosylanthranilate isomerase; phosphoribosylanthranilate isomerase 114933 7114045 Mchl_0119 Methylobacterium extorquens CM4 phosphoribosylanthranilate isomerase YP_002418997.1 114286 R 440085 CDS YP_002418998.1 218528182 7114046 complement(114950..115318) 1 NC_011757.1 KEGG: mex:Mext_0178 hypothetical protein; hypothetical protein 115318 7114046 Mchl_0120 Methylobacterium extorquens CM4 hypothetical protein YP_002418998.1 114950 R 440085 CDS YP_002418999.1 218528183 7114047 complement(115544..115852) 1 NC_011757.1 TIGRFAM: integration host factor subunit beta; PFAM: histone family protein DNA-binding protein; KEGG: mex:Mext_0179 integration host factor subunit beta; integration host factor subunit beta 115852 7114047 Mchl_0121 Methylobacterium extorquens CM4 integration host factor subunit beta YP_002418999.1 115544 R 440085 CDS YP_002419000.1 218528184 7114048 complement(115894..116859) 1 NC_011757.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: mex:Mext_0180 signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 36K type 116859 7114048 Mchl_0122 Methylobacterium extorquens CM4 signal peptide peptidase SppA, 36K type YP_002419000.1 115894 R 440085 CDS YP_002419001.1 218528185 7114049 complement(117120..118445) 1 NC_011757.1 KEGG: mex:Mext_0181 hypothetical protein; hypothetical protein 118445 7114049 Mchl_0123 Methylobacterium extorquens CM4 hypothetical protein YP_002419001.1 117120 R 440085 CDS YP_002419002.1 218528186 7114050 complement(118538..120250) 1 NC_011757.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 120250 rpsA 7114050 rpsA Methylobacterium extorquens CM4 30S ribosomal protein S1 YP_002419002.1 118538 R 440085 CDS YP_002419003.1 218528187 7114051 complement(120665..121471) 1 NC_011757.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: mex:Mext_0183 RNA methyltransferase; TrmH family RNA methyltransferase 121471 7114051 Mchl_0125 Methylobacterium extorquens CM4 TrmH family RNA methyltransferase YP_002419003.1 120665 R 440085 CDS YP_002419004.1 218528188 7114055 123036..123974 1 NC_011757.1 PFAM: pirin; KEGG: mex:Mext_0185 pirin domain-containing protein; pirin 123974 7114055 Mchl_0128 Methylobacterium extorquens CM4 pirin YP_002419004.1 123036 D 440085 CDS YP_002419005.1 218528189 7114056 124077..125843 1 NC_011757.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mex:Mext_0186 potassium efflux system protein; potassium efflux system protein 125843 7114056 Mchl_0129 Methylobacterium extorquens CM4 potassium efflux system protein YP_002419005.1 124077 D 440085 CDS YP_002419006.1 218528190 7114057 126023..126742 1 NC_011757.1 PFAM: cytochrome C biogenesis protein transmembrane region; KEGG: mex:Mext_0187 cytochrome C biogenesis protein transmembrane region; cytochrome C biogenesis protein transmembrane region 126742 7114057 Mchl_0130 Methylobacterium extorquens CM4 cytochrome C biogenesis protein transmembrane region YP_002419006.1 126023 D 440085 CDS YP_002419007.1 218528191 7114058 126850..127464 1 NC_011757.1 PFAM: HhH-GPD family protein; KEGG: mex:Mext_0188 HhH-GPD family protein; HhH-GPD family protein 127464 7114058 Mchl_0131 Methylobacterium extorquens CM4 HhH-GPD family protein YP_002419007.1 126850 D 440085 CDS YP_002419008.1 218528192 7114059 complement(127470..127727) 1 NC_011757.1 KEGG: mex:Mext_0189 hypothetical protein; hypothetical protein 127727 7114059 Mchl_0132 Methylobacterium extorquens CM4 hypothetical protein YP_002419008.1 127470 R 440085 CDS YP_002419009.1 218528193 7117043 128055..128273 1 NC_011757.1 KEGG: mex:Mext_0190 hypothetical protein; hypothetical protein 128273 7117043 Mchl_0133 Methylobacterium extorquens CM4 hypothetical protein YP_002419009.1 128055 D 440085 CDS YP_002419010.1 218528194 7117617 complement(128389..130086) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0191 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 130086 7117617 Mchl_0134 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002419010.1 128389 R 440085 CDS YP_002419011.1 218528195 7117618 130470..132092 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_0192 ABC transporter; ABC transporter 132092 7117618 Mchl_0135 Methylobacterium extorquens CM4 ABC transporter YP_002419011.1 130470 D 440085 CDS YP_002419012.1 218528196 7117619 complement(132100..132456) 1 NC_011757.1 KEGG: mex:Mext_0193 hypothetical protein; hypothetical protein 132456 7117619 Mchl_0136 Methylobacterium extorquens CM4 hypothetical protein YP_002419012.1 132100 R 440085 CDS YP_002419013.1 218528197 7117620 complement(132466..132705) 1 NC_011757.1 KEGG: mex:Mext_0194 hypothetical protein; hypothetical protein 132705 7117620 Mchl_0137 Methylobacterium extorquens CM4 hypothetical protein YP_002419013.1 132466 R 440085 CDS YP_002419014.1 218528198 7117621 complement(132916..133560) 1 NC_011757.1 KEGG: mex:Mext_0195 hypothetical protein; hypothetical protein 133560 7117621 Mchl_0138 Methylobacterium extorquens CM4 hypothetical protein YP_002419014.1 132916 R 440085 CDS YP_002419015.1 218528199 7117622 complement(133571..134206) 1 NC_011757.1 KEGG: mex:Mext_0196 hypothetical protein; hypothetical protein 134206 7117622 Mchl_0139 Methylobacterium extorquens CM4 hypothetical protein YP_002419015.1 133571 R 440085 CDS YP_002419016.1 218528200 7117623 134307..135296 1 NC_011757.1 KEGG: mex:Mext_0197 hypothetical protein; hypothetical protein 135296 7117623 Mchl_0140 Methylobacterium extorquens CM4 hypothetical protein YP_002419016.1 134307 D 440085 CDS YP_002419017.1 218528201 7117624 complement(135317..136501) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_0198 glycosyl transferase group 1; group 1 glycosyl transferase 136501 7117624 Mchl_0141 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002419017.1 135317 R 440085 CDS YP_002419018.1 218528202 7117625 complement(136501..137541) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_0199 glycosyl transferase group 1; group 1 glycosyl transferase 137541 7117625 Mchl_0142 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002419018.1 136501 R 440085 CDS YP_002419019.1 218528203 7117626 137599..139653 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: glycosyl transferase group 1; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: mex:Mext_0200 HAD family hydrolase; HAD-superfamily hydrolase 139653 7117626 Mchl_0143 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002419019.1 137599 D 440085 CDS YP_002419020.1 218528204 7117627 139711..140565 1 NC_011757.1 KEGG: mex:Mext_0201 sugar transferase; sugar transferase 140565 7117627 Mchl_0144 Methylobacterium extorquens CM4 sugar transferase YP_002419020.1 139711 D 440085 CDS YP_002419021.1 218528205 7117628 140629..141777 1 NC_011757.1 KEGG: mex:Mext_0202 hypothetical protein; hypothetical protein 141777 7117628 Mchl_0145 Methylobacterium extorquens CM4 hypothetical protein YP_002419021.1 140629 D 440085 CDS YP_002419022.1 218528206 7117629 141827..142768 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_0203 glycosyl transferase; family 2 glycosyl transferase 142768 7117629 Mchl_0146 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419022.1 141827 D 440085 CDS YP_002419023.1 218528207 7117630 142765..143820 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_0204 glycosyl transferase group 1; group 1 glycosyl transferase 143820 7117630 Mchl_0147 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002419023.1 142765 D 440085 CDS YP_002419024.1 218528208 7117631 143865..144533 1 NC_011757.1 KEGG: mex:Mext_0205 hypothetical protein; hypothetical protein 144533 7117631 Mchl_0148 Methylobacterium extorquens CM4 hypothetical protein YP_002419024.1 143865 D 440085 CDS YP_002419025.1 218528209 7117633 145220..146329 1 NC_011757.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_0206 metal-dependent phosphohydrolase; response regulator receiver modulated metal dependent phosphohydrolase 146329 7117633 Mchl_0150 Methylobacterium extorquens CM4 response regulator receiver modulated metal dependent phosphohydrolase YP_002419025.1 145220 D 440085 CDS YP_002419026.1 218528210 7117634 146481..149177 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_0207 ABC transporter related; ABC transporter 149177 7117634 Mchl_0151 Methylobacterium extorquens CM4 ABC transporter YP_002419026.1 146481 D 440085 CDS YP_002419027.1 218528211 7117635 complement(149218..150174) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: mex:Mext_0208 ThiJ/PfpI domain-containing protein; AraC family transcriptional regulator 150174 7117635 Mchl_0152 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419027.1 149218 R 440085 CDS YP_002419028.1 218528212 7117636 150302..151090 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_0209 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 151090 7117636 Mchl_0153 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419028.1 150302 D 440085 CDS YP_002419029.1 218528213 7117637 151283..151729 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_0210 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 151729 7117637 Mchl_0154 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002419029.1 151283 D 440085 CDS YP_002419030.1 218528214 7117638 151740..153998 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_0211 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 153998 7117638 Mchl_0155 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002419030.1 151740 D 440085 CDS YP_002419031.1 218528215 7117639 154009..155016 1 NC_011757.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: mex:Mext_0212 C4-dicarboxylate transporter/malic acid transport protein; C4-dicarboxylate transporter/malic acid transport protein 155016 7117639 Mchl_0156 Methylobacterium extorquens CM4 C4-dicarboxylate transporter/malic acid transport protein YP_002419031.1 154009 D 440085 CDS YP_002419032.1 218528216 7117640 155248..156498 1 NC_011757.1 PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_0213 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 156498 7117640 Mchl_0157 Methylobacterium extorquens CM4 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_002419032.1 155248 D 440085 CDS YP_002419033.1 218528217 7117641 156514..157911 1 NC_011757.1 PFAM: FAD linked oxidase; KEGG: mex:Mext_0214 FAD linked oxidase domain-containing protein; FAD linked oxidase 157911 7117641 Mchl_0158 Methylobacterium extorquens CM4 FAD linked oxidase YP_002419033.1 156514 D 440085 CDS YP_002419034.1 218528218 7117642 158644..159303 1 NC_011757.1 KEGG: mex:Mext_0215 chaperone protein HtpG; chaperone protein HtpG 159303 7117642 Mchl_0159 Methylobacterium extorquens CM4 chaperone protein HtpG YP_002419034.1 158644 D 440085 CDS YP_002419035.1 218528219 7117643 159291..162101 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mex:Mext_0216 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 162101 7117643 Mchl_0160 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002419035.1 159291 D 440085 CDS YP_002419036.1 218528220 7117644 162098..163468 1 NC_011757.1 PFAM: polysulphide reductase NrfD; KEGG: mex:Mext_0217 polysulphide reductase NrfD; polysulfide reductase NrfD 163468 7117644 Mchl_0161 Methylobacterium extorquens CM4 polysulfide reductase NrfD YP_002419036.1 162098 D 440085 CDS YP_002419037.1 218528221 7117645 163465..163983 1 NC_011757.1 KEGG: mex:Mext_0218 hypothetical protein; hypothetical protein 163983 7117645 Mchl_0162 Methylobacterium extorquens CM4 hypothetical protein YP_002419037.1 163465 D 440085 CDS YP_002419038.1 218528222 7117646 163980..164507 1 NC_011757.1 KEGG: mex:Mext_0219 hypothetical protein; hypothetical protein 164507 7117646 Mchl_0163 Methylobacterium extorquens CM4 hypothetical protein YP_002419038.1 163980 D 440085 CDS YP_002419039.1 218528223 7117647 164504..165460 1 NC_011757.1 KEGG: mex:Mext_0220 hypothetical protein; hypothetical protein 165460 7117647 Mchl_0164 Methylobacterium extorquens CM4 hypothetical protein YP_002419039.1 164504 D 440085 CDS YP_002419040.1 218528224 7117648 165453..165974 1 NC_011757.1 KEGG: mex:Mext_0221 hypothetical protein; hypothetical protein 165974 7117648 Mchl_0165 Methylobacterium extorquens CM4 hypothetical protein YP_002419040.1 165453 D 440085 CDS YP_002419041.1 218528225 7117649 165974..167062 1 NC_011757.1 TIGRFAM: cytochrome C oxidase subunit II; PFAM: cytochrome C oxidase subunit II; cytochrome C class I; KEGG: mex:Mext_0222 cytochrome C oxidase subunit II; cytochrome C oxidase subunit II 167062 7117649 Mchl_0166 Methylobacterium extorquens CM4 cytochrome C oxidase subunit II YP_002419041.1 165974 D 440085 CDS YP_002419042.1 218528226 7117650 167094..168785 1 NC_011757.1 KEGG: mex:Mext_0223 cytochrome C oxidase subunit I; TIGRFAM: cytochrome C oxidase subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase subunit I 168785 7117650 Mchl_0167 Methylobacterium extorquens CM4 cytochrome C oxidase subunit I YP_002419042.1 167094 D 440085 CDS YP_002419043.1 218528227 7117651 168782..169471 1 NC_011757.1 PFAM: cytochrome C oxidase subunit III; KEGG: mex:Mext_0224 cytochrome C oxidase subunit III; cytochrome C oxidase subunit III 169471 7117651 Mchl_0168 Methylobacterium extorquens CM4 cytochrome C oxidase subunit III YP_002419043.1 168782 D 440085 CDS YP_002419044.1 218528228 7117652 169468..169770 1 NC_011757.1 TIGRFAM: caa(3)-type oxidase subunit IV; KEGG: mex:Mext_0225 caa(3)-type oxidase subunit IV; caa(3)-type oxidase subunit IV 169770 7117652 Mchl_0169 Methylobacterium extorquens CM4 caa(3)-type oxidase subunit IV YP_002419044.1 169468 D 440085 CDS YP_002419045.1 218528229 7117654 complement(170285..170569) 1 NC_011757.1 KEGG: mex:Mext_0227 hypothetical protein; hypothetical protein 170569 7117654 Mchl_0171 Methylobacterium extorquens CM4 hypothetical protein YP_002419045.1 170285 R 440085 CDS YP_002419046.1 218528230 7117655 170836..171366 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_0228 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 171366 7117655 Mchl_0172 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002419046.1 170836 D 440085 CDS YP_002419047.1 218528231 7117656 171369..172136 1 NC_011757.1 KEGG: mex:Mext_0229 hypothetical protein; transmembrane anti-sigma factor 172136 7117656 Mchl_0173 Methylobacterium extorquens CM4 transmembrane anti-sigma factor YP_002419047.1 171369 D 440085 CDS YP_002419048.1 218528232 7117657 172144..173256 1 NC_011757.1 PFAM: catalase; KEGG: mex:Mext_0230 catalase domain-containing protein; catalase 173256 7117657 Mchl_0174 Methylobacterium extorquens CM4 catalase YP_002419048.1 172144 D 440085 CDS YP_002419049.1 218528233 7117658 173253..173819 1 NC_011757.1 PFAM: cytochrome B561; KEGG: mex:Mext_0231 cytochrome b561; cytochrome B561 173819 7117658 Mchl_0175 Methylobacterium extorquens CM4 cytochrome B561 YP_002419049.1 173253 D 440085 CDS YP_002419050.1 218528234 7117659 173875..174096 1 NC_011757.1 hypothetical protein 174096 7117659 Mchl_0176 Methylobacterium extorquens CM4 hypothetical protein YP_002419050.1 173875 D 440085 CDS YP_002419051.1 218528235 7117660 174417..176132 1 NC_011757.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase A 176132 7117660 Mchl_0177 Methylobacterium extorquens CM4 potassium-transporting ATPase A YP_002419051.1 174417 D 440085 CDS YP_002419052.1 218528236 7117661 176134..176322 1 NC_011757.1 KEGG: mpo:Mpop_0953 hypothetical protein; hypothetical protein 176322 7117661 Mchl_0178 Methylobacterium extorquens CM4 hypothetical protein YP_002419052.1 176134 D 440085 CDS YP_002419053.1 218528237 7117662 176382..178472 1 NC_011757.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase subunit beta; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mex:Mext_0234 K+-transporting ATPase subunit beta; K+-transporting ATPase subunit beta 178472 7117662 Mchl_0179 Methylobacterium extorquens CM4 K+-transporting ATPase subunit beta YP_002419053.1 176382 D 440085 CDS YP_002419054.1 218528238 7117663 178496..179101 1 NC_011757.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase C 179101 7117663 Mchl_0180 Methylobacterium extorquens CM4 potassium-transporting ATPase C YP_002419054.1 178496 D 440085 CDS YP_002419055.1 218528239 7117664 179112..181829 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: mex:Mext_0236 osmosensitive K channel His kinase sensor; osmosensitive K+ channel signal transduction histidine kinase 181829 7117664 Mchl_0181 Methylobacterium extorquens CM4 osmosensitive K+ channel signal transduction histidine kinase YP_002419055.1 179112 D 440085 CDS YP_002419056.1 218528240 7117665 181826..182572 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_0237 response regulator receiver; transcriptional regulator 182572 7117665 Mchl_0182 Methylobacterium extorquens CM4 transcriptional regulator YP_002419056.1 181826 D 440085 CDS YP_002419057.1 218528241 7117666 complement(182791..183042) 1 NC_011757.1 KEGG: mex:Mext_0238 hypothetical protein; hypothetical protein 183042 7117666 Mchl_0183 Methylobacterium extorquens CM4 hypothetical protein YP_002419057.1 182791 R 440085 CDS YP_002419058.1 218528242 7117667 183234..184595 1 NC_011757.1 KEGG: mex:Mext_0239 TRAP-type uncharacterized transport system periplasmic component-like protein; TRAP-type transporter periplasmic component-like protein 184595 7117667 Mchl_0184 Methylobacterium extorquens CM4 TRAP-type transporter periplasmic component-like protein YP_002419058.1 183234 D 440085 CDS YP_002419059.1 218528243 7117669 complement(184900..185838) 1 NC_011757.1 KEGG: mex:Mext_0240 hypothetical protein; hypothetical protein 185838 7117669 Mchl_0186 Methylobacterium extorquens CM4 hypothetical protein YP_002419059.1 184900 R 440085 CDS YP_002419060.1 218528244 7117670 complement(185835..186623) 1 NC_011757.1 PFAM: methyltransferase ; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_0241 methyltransferase type 11; type 11 methyltransferase 186623 7117670 Mchl_0187 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002419060.1 185835 R 440085 CDS YP_002419061.1 218528245 7117671 complement(186620..187405) 1 NC_011757.1 PFAM: phosphoglycerate mutase; KEGG: mex:Mext_0242 phosphoglycerate mutase; phosphoglycerate mutase 187405 7117671 Mchl_0188 Methylobacterium extorquens CM4 phosphoglycerate mutase YP_002419061.1 186620 R 440085 CDS YP_002419062.1 218528246 7117672 complement(187402..188499) 1 NC_011757.1 PFAM: myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase GAPDH domain protein; KEGG: mex:Mext_0243 myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase 188499 7117672 Mchl_0189 Methylobacterium extorquens CM4 myo-inositol-1-phosphate synthase YP_002419062.1 187402 R 440085 CDS YP_002419063.1 218528247 7117673 complement(188499..189539) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_0244 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 189539 7117673 Mchl_0190 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002419063.1 188499 R 440085 CDS YP_002419064.1 218528248 7117674 complement(189551..190666) 1 NC_011757.1 KEGG: mex:Mext_0245 hypothetical protein; hypothetical protein 190666 7117674 Mchl_0191 Methylobacterium extorquens CM4 hypothetical protein YP_002419064.1 189551 R 440085 CDS YP_002419065.1 218528249 7117675 complement(190663..191769) 1 NC_011757.1 KEGG: mex:Mext_0246 hypothetical protein; hypothetical protein 191769 7117675 Mchl_0192 Methylobacterium extorquens CM4 hypothetical protein YP_002419065.1 190663 R 440085 CDS YP_002419066.1 218528250 7117676 complement(191766..192893) 1 NC_011757.1 KEGG: mex:Mext_0247 hypothetical protein; hypothetical protein 192893 7117676 Mchl_0193 Methylobacterium extorquens CM4 hypothetical protein YP_002419066.1 191766 R 440085 CDS YP_002419067.1 218528251 7117677 complement(192890..193996) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_0248 glycosyl transferase group 1; group 1 glycosyl transferase 193996 7117677 Mchl_0194 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002419067.1 192890 R 440085 CDS YP_002419068.1 218528252 7117678 complement(193987..195282) 1 NC_011757.1 PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mex:Mext_0249 radical SAM domain-containing protein; radical SAM protein 195282 7117678 Mchl_0195 Methylobacterium extorquens CM4 radical SAM protein YP_002419068.1 193987 R 440085 CDS YP_002419069.1 218528253 7117679 complement(195279..196370) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_0250 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 196370 7117679 Mchl_0196 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002419069.1 195279 R 440085 CDS YP_002419070.1 218528254 7117680 complement(196367..197479) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: mex:Mext_0251 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 197479 7117680 Mchl_0197 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002419070.1 196367 R 440085 CDS YP_002419071.1 218528255 7117683 198940..200178 1 NC_011757.1 PFAM: peptidase M16 domain protein; KEGG: mpo:Mpop_2284 peptidase M16 domain protein; peptidase M16 domain-containing protein 200178 7117683 Mchl_0200 Methylobacterium extorquens CM4 peptidase M16 domain-containing protein YP_002419071.1 198940 D 440085 CDS YP_002419072.1 218528256 7117684 200298..201404 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: met:M446_4177 redoxin domain-containing protein; redoxin 201404 7117684 Mchl_0201 Methylobacterium extorquens CM4 redoxin YP_002419072.1 200298 D 440085 CDS YP_002419073.1 218528257 7117685 201460..201939 1 NC_011757.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: sme:SMc01851 amino acid efflux protein; lysine exporter LysE/YggA 201939 7117685 Mchl_0202 Methylobacterium extorquens CM4 lysine exporter LysE/YggA YP_002419073.1 201460 D 440085 CDS YP_002419074.1 218528258 7117686 complement(202336..203262) 1 NC_011757.1 TIGRFAM: arginase; PFAM: arginase/agmatinase/formiminoglutamase; KEGG: met:M446_1825 arginase; arginase 203262 7117686 Mchl_0203 Methylobacterium extorquens CM4 arginase YP_002419074.1 202336 R 440085 CDS YP_002419075.1 218528259 7117687 complement(203265..204458) 1 NC_011757.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mpo:Mpop_4647 pyridoxal-5'-phosphate-dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein subunit beta 204458 7117687 Mchl_0204 Methylobacterium extorquens CM4 pyridoxal-5'-phosphate-dependent protein subunit beta YP_002419075.1 203265 R 440085 CDS YP_002419076.1 218528260 7117688 complement(204455..204871) 1 NC_011757.1 PFAM: Secretin/TonB short domain; KEGG: mpo:Mpop_4653 TonB-dependent receptor plug; Secretin/TonB short domain 204871 7117688 Mchl_0205 Methylobacterium extorquens CM4 Secretin/TonB short domain YP_002419076.1 204455 R 440085 CDS YP_002419077.1 218528261 7117689 complement(205082..206050) 1 NC_011757.1 PFAM: FecR protein; KEGG: met:M446_3438 anti-FecI sigma factor, FecR; anti-FecI sigma factor FecR 206050 7117689 Mchl_0206 Methylobacterium extorquens CM4 anti-FecI sigma factor FecR YP_002419077.1 205082 R 440085 CDS YP_002419078.1 218528262 7117690 complement(206069..206587) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_3437 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 206587 7117690 Mchl_0207 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002419078.1 206069 R 440085 CDS YP_002419079.1 218528263 7117692 complement(207983..209938) 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_3812 hypothetical protein; hypothetical protein 209938 7117692 Mchl_0209 Methylobacterium extorquens CM4 hypothetical protein YP_002419079.1 207983 R 440085 CDS YP_002419080.1 218528264 7117693 210118..211620 1 NC_011757.1 KEGG: mex:Mext_3813 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; LuxR family transcriptional regulator 211620 7117693 Mchl_0210 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002419080.1 210118 D 440085 CDS YP_002419081.1 218528265 7117694 211760..211942 1 NC_011757.1 hypothetical protein 211942 7117694 Mchl_0211 Methylobacterium extorquens CM4 hypothetical protein YP_002419081.1 211760 D 440085 CDS YP_002419082.1 218528266 7117695 212044..212304 1 NC_011757.1 PFAM: transglycosylase; KEGG: mex:Mext_3814 transglycosylase; transglycosylase 212304 7117695 Mchl_0212 Methylobacterium extorquens CM4 transglycosylase YP_002419082.1 212044 D 440085 CDS YP_002419083.1 218528267 7117696 212353..213327 1 NC_011757.1 KEGG: mex:Mext_3815 hypothetical protein; hypothetical protein 213327 7117696 Mchl_0213 Methylobacterium extorquens CM4 hypothetical protein YP_002419083.1 212353 D 440085 CDS YP_002419084.1 218528268 7117697 213324..213815 1 NC_011757.1 KEGG: mex:Mext_3816 hypothetical protein; hypothetical protein 213815 7117697 Mchl_0214 Methylobacterium extorquens CM4 hypothetical protein YP_002419084.1 213324 D 440085 CDS YP_002419085.1 218528269 7118841 213812..214696 1 NC_011757.1 KEGG: mex:Mext_3817 hypothetical protein; hypothetical protein 214696 7118841 Mchl_0215 Methylobacterium extorquens CM4 hypothetical protein YP_002419085.1 213812 D 440085 CDS YP_002419086.1 218528270 7118844 complement(215428..216336) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3801 carbonate dehydratase; LysR family transcriptional regulator 216336 7118844 Mchl_0217 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002419086.1 215428 R 440085 CDS YP_002419087.1 218528271 7118845 216431..217312 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_3802 aldo/keto reductase; aldo/keto reductase 217312 7118845 Mchl_0218 Methylobacterium extorquens CM4 aldo/keto reductase YP_002419087.1 216431 D 440085 CDS YP_002419088.1 218528272 7118846 217739..219208 1 NC_011757.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: mex:Mext_3803 diguanylate cyclase; PAS/PAC and GAF sensor-containing diguanylate cyclase 219208 7118846 Mchl_0219 Methylobacterium extorquens CM4 PAS/PAC and GAF sensor-containing diguanylate cyclase YP_002419088.1 217739 D 440085 CDS YP_002419089.1 218528273 7118847 complement(219563..221359) 1 NC_011757.1 PFAM: EAL domain protein; GAF domain protein; KEGG: mex:Mext_3804 EAL domain-containing protein; diguanylate phosphodiesterase 221359 7118847 Mchl_0220 Methylobacterium extorquens CM4 diguanylate phosphodiesterase YP_002419089.1 219563 R 440085 CDS YP_002419090.1 218528274 7118848 complement(221756..222064) 1 NC_011757.1 KEGG: mex:Mext_3805 hypothetical protein; hypothetical protein 222064 7118848 Mchl_0221 Methylobacterium extorquens CM4 hypothetical protein YP_002419090.1 221756 R 440085 CDS YP_002419091.1 218528275 7118849 222275..223318 1 NC_011757.1 PFAM: regulatory protein LysR; KEGG: mex:Mext_3806 regulatory protein LysR; transcriptional regulator of molybdate metabolism, LysR family 223318 7118849 Mchl_0222 Methylobacterium extorquens CM4 transcriptional regulator of molybdate metabolism, LysR family YP_002419091.1 222275 D 440085 CDS YP_002419092.1 218528276 7118850 223857..224921 1 NC_011757.1 KEGG: mex:Mext_3807 hypothetical protein; hypothetical protein 224921 7118850 Mchl_0223 Methylobacterium extorquens CM4 hypothetical protein YP_002419092.1 223857 D 440085 CDS YP_002419093.1 218528277 7118851 224967..226070 1 NC_011757.1 KEGG: mex:Mext_3808 hypothetical protein; hypothetical protein 226070 7118851 Mchl_0224 Methylobacterium extorquens CM4 hypothetical protein YP_002419093.1 224967 D 440085 CDS YP_002419094.1 218528278 7118852 complement(226183..226806) 1 NC_011757.1 KEGG: mrd:Mrad2831_4845 hypothetical protein; hypothetical protein 226806 7118852 Mchl_0225 Methylobacterium extorquens CM4 hypothetical protein YP_002419094.1 226183 R 440085 CDS YP_002419095.1 218528279 7118853 complement(227015..227473) 1 NC_011757.1 hypothetical protein 227473 7118853 Mchl_0226 Methylobacterium extorquens CM4 hypothetical protein YP_002419095.1 227015 R 440085 CDS YP_002419096.1 218528280 7118854 complement(227550..227810) 1 NC_011757.1 KEGG: mex:Mext_3810 hypothetical protein; hypothetical protein 227810 7118854 Mchl_0227 Methylobacterium extorquens CM4 hypothetical protein YP_002419096.1 227550 R 440085 CDS YP_002419097.1 218528281 7118855 complement(227934..228380) 1 NC_011757.1 KEGG: mex:Mext_3359 hypothetical protein; hypothetical protein 228380 7118855 Mchl_0228 Methylobacterium extorquens CM4 hypothetical protein YP_002419097.1 227934 R 440085 CDS YP_002419098.1 218528282 7118856 complement(228465..228668) 1 NC_011757.1 KEGG: mex:Mext_3360 hypothetical protein; hypothetical protein 228668 7118856 Mchl_0229 Methylobacterium extorquens CM4 hypothetical protein YP_002419098.1 228465 R 440085 CDS YP_002419099.1 218528283 7118857 complement(228707..229051) 1 NC_011757.1 KEGG: mex:Mext_3361 hypothetical protein; hypothetical protein 229051 7118857 Mchl_0230 Methylobacterium extorquens CM4 hypothetical protein YP_002419099.1 228707 R 440085 CDS YP_002419100.1 218528284 7118858 complement(229097..229399) 1 NC_011757.1 KEGG: mrd:Mrad2831_4908 hypothetical protein; hypothetical protein 229399 7118858 Mchl_0231 Methylobacterium extorquens CM4 hypothetical protein YP_002419100.1 229097 R 440085 CDS YP_002419101.1 218528285 7118861 complement(231053..232048) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rpc:RPC_2016 AraC family transcriptional regulator; AraC family transcriptional regulator 232048 7118861 Mchl_0234 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419101.1 231053 R 440085 CDS YP_002419102.1 218528286 7118862 complement(232097..232654) 1 NC_011757.1 PFAM: type IV pilus assembly PilZ; KEGG: met:M446_4427 type IV pilus assembly PilZ; type IV pilus assembly PilZ 232654 7118862 Mchl_0235 Methylobacterium extorquens CM4 type IV pilus assembly PilZ YP_002419102.1 232097 R 440085 CDS YP_002419103.1 218528287 7118863 complement(232654..233535) 1 NC_011757.1 KEGG: mva:Mvan_3112 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 233535 7118863 Mchl_0236 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002419103.1 232654 R 440085 CDS YP_002419104.1 218528288 7118864 complement(233537..234532) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rpc:RPC_2016 AraC family transcriptional regulator; AraC family transcriptional regulator 234532 7118864 Mchl_0237 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419104.1 233537 R 440085 CDS YP_002419105.1 218528289 7118865 234827..236125 1 NC_011757.1 KEGG: mpo:Mpop_1194 conserved hypothetical protein; flagellin C-ter domain; hypothetical protein 236125 7118865 Mchl_0238 Methylobacterium extorquens CM4 hypothetical protein YP_002419105.1 234827 D 440085 CDS YP_002419106.1 218528290 7118866 236306..236659 1 NC_011757.1 KEGG: mag:amb0529 hypothetical protein; hypothetical protein 236659 7118866 Mchl_0239 Methylobacterium extorquens CM4 hypothetical protein YP_002419106.1 236306 D 440085 CDS YP_002419107.1 218528291 7118867 236677..237588 1 NC_011757.1 KEGG: rpt:Rpal_2114 hypothetical protein; hypothetical protein 237588 7118867 Mchl_0240 Methylobacterium extorquens CM4 hypothetical protein YP_002419107.1 236677 D 440085 CDS YP_002419108.1 218528292 7118868 237619..238128 1 NC_011757.1 hypothetical protein 238128 7118868 Mchl_0241 Methylobacterium extorquens CM4 hypothetical protein YP_002419108.1 237619 D 440085 CDS YP_002419109.1 218528293 7118869 238298..240046 1 NC_011757.1 PFAM: flagellin domain protein; KEGG: met:M446_5135 flagellin domain-containing protein; flagellin domain-containing protein 240046 7118869 Mchl_0242 Methylobacterium extorquens CM4 flagellin domain-containing protein YP_002419109.1 238298 D 440085 CDS YP_002419110.1 218528294 7118870 complement(240257..241786) 1 NC_011757.1 PFAM: integrase family protein; KEGG: rpe:RPE_0558 phage integrase family protein; integrase family protein 241786 7118870 Mchl_0243 Methylobacterium extorquens CM4 integrase family protein YP_002419110.1 240257 R 440085 CDS YP_002419111.1 218528295 7118871 242065..243291 1 NC_011757.1 PFAM: integrase family protein; KEGG: mrd:Mrad2831_5749 integrase family protein; integrase family protein 243291 7118871 Mchl_0244 Methylobacterium extorquens CM4 integrase family protein YP_002419111.1 242065 D 440085 CDS YP_002419112.1 218528296 7118872 complement(243213..243455) 1 NC_011757.1 PFAM: regulatory protein MerR; Prophage CP4-57 regulatory; KEGG: mpo:Mpop_1340 DNA binding domain protein, excisionase family; prophage CP4-57 regulator 243455 7118872 Mchl_0245 Methylobacterium extorquens CM4 prophage CP4-57 regulator YP_002419112.1 243213 R 440085 CDS YP_002419113.1 218528297 7118873 243571..243789 1 NC_011757.1 KEGG: mpo:Mpop_5395 hypothetical protein; hypothetical protein 243789 7118873 Mchl_0246 Methylobacterium extorquens CM4 hypothetical protein YP_002419113.1 243571 D 440085 CDS YP_002419114.1 218528298 7118874 244015..244194 1 NC_011757.1 hypothetical protein 244194 7118874 Mchl_0247 Methylobacterium extorquens CM4 hypothetical protein YP_002419114.1 244015 D 440085 CDS YP_002419115.1 218528299 7118875 complement(244227..244442) 1 NC_011757.1 hypothetical protein 244442 7118875 Mchl_0248 Methylobacterium extorquens CM4 hypothetical protein YP_002419115.1 244227 R 440085 CDS YP_002419116.1 218528300 7118876 complement(244426..245298) 1 NC_011757.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: mag:amb1159 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase/FAD synthetase and related enzyme; phosphoadenosine phosphosulfate reductase 245298 7118876 Mchl_0249 Methylobacterium extorquens CM4 phosphoadenosine phosphosulfate reductase YP_002419116.1 244426 R 440085 CDS YP_002419117.1 218528301 7118877 complement(245322..245717) 1 NC_011757.1 KEGG: mpo:Mpop_2730 hypothetical protein; hypothetical protein 245717 7118877 Mchl_0250 Methylobacterium extorquens CM4 hypothetical protein YP_002419117.1 245322 R 440085 CDS YP_002419118.1 218528302 7118878 complement(245711..246061) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: nfa:nfa22390 transcriptional regulator; XRE family transcriptional regulator 246061 7118878 Mchl_0251 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419118.1 245711 R 440085 CDS YP_002419119.1 218528303 7118879 complement(246065..246496) 1 NC_011757.1 KEGG: mrd:Mrad2831_1232 HNH nuclease; hypothetical protein 246496 7118879 Mchl_0252 Methylobacterium extorquens CM4 hypothetical protein YP_002419119.1 246065 R 440085 CDS YP_002419120.1 218528304 7118880 complement(246493..246702) 1 NC_011757.1 hypothetical protein 246702 7118880 Mchl_0253 Methylobacterium extorquens CM4 hypothetical protein YP_002419120.1 246493 R 440085 CDS YP_002419121.1 218528305 7118881 complement(246699..246995) 1 NC_011757.1 hypothetical protein 246995 7118881 Mchl_0254 Methylobacterium extorquens CM4 hypothetical protein YP_002419121.1 246699 R 440085 CDS YP_002419122.1 218528306 7118882 complement(246997..247278) 1 NC_011757.1 KEGG: UCP2; uncoupling protein; hypothetical protein 247278 7118882 Mchl_0255 Methylobacterium extorquens CM4 hypothetical protein YP_002419122.1 246997 R 440085 CDS YP_002419123.1 218528307 7118883 complement(247285..247803) 1 NC_011757.1 hypothetical protein 247803 7118883 Mchl_0256 Methylobacterium extorquens CM4 hypothetical protein YP_002419123.1 247285 R 440085 CDS YP_002419124.1 218528308 7118884 complement(247870..248310) 1 NC_011757.1 KEGG: met:M446_0951 hypothetical protein; hypothetical protein 248310 7118884 Mchl_0257 Methylobacterium extorquens CM4 hypothetical protein YP_002419124.1 247870 R 440085 CDS YP_002419125.1 218528309 7118885 complement(248747..249439) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; peptidase S24 and S26 domain protein; KEGG: gbe:GbCGDNIH1_1593 transcriptional repressor; phage repressor 249439 7118885 Mchl_0258 Methylobacterium extorquens CM4 phage repressor YP_002419125.1 248747 R 440085 CDS YP_002419126.1 218528310 7118886 249528..249776 1 NC_011757.1 KEGG: ecp:ECP_1147 hypothetical protein; hypothetical protein 249776 7118886 Mchl_0259 Methylobacterium extorquens CM4 hypothetical protein YP_002419126.1 249528 D 440085 CDS YP_002419127.1 218528311 7118887 249784..249933 1 NC_011757.1 hypothetical protein 249933 7118887 Mchl_0260 Methylobacterium extorquens CM4 hypothetical protein YP_002419127.1 249784 D 440085 CDS YP_002419128.1 218528312 7118888 complement(249972..250244) 1 NC_011757.1 hypothetical protein 250244 7118888 Mchl_0261 Methylobacterium extorquens CM4 hypothetical protein YP_002419128.1 249972 R 440085 CDS YP_002419129.1 218528313 7118889 complement(250430..250678) 1 NC_011757.1 hypothetical protein 250678 7118889 Mchl_0262 Methylobacterium extorquens CM4 hypothetical protein YP_002419129.1 250430 R 440085 CDS YP_002419130.1 218528314 7118890 250900..251322 1 NC_011757.1 KEGG: mrd:Mrad2831_5725 hypothetical protein; hypothetical protein 251322 7118890 Mchl_0263 Methylobacterium extorquens CM4 hypothetical protein YP_002419130.1 250900 D 440085 CDS YP_002419131.1 218528315 7118891 251409..251972 1 NC_011757.1 PFAM: endodeoxyribonuclease RusA; KEGG: mex:Mext_2442 hypothetical protein; endodeoxyribonuclease RusA 251972 7118891 Mchl_0264 Methylobacterium extorquens CM4 endodeoxyribonuclease RusA YP_002419131.1 251409 D 440085 CDS YP_002419132.1 218528316 7118892 251969..252175 1 NC_011757.1 hypothetical protein 252175 7118892 Mchl_0265 Methylobacterium extorquens CM4 hypothetical protein YP_002419132.1 251969 D 440085 CDS YP_002419133.1 218528317 7118893 252172..252399 1 NC_011757.1 hypothetical protein 252399 7118893 Mchl_0266 Methylobacterium extorquens CM4 hypothetical protein YP_002419133.1 252172 D 440085 CDS YP_002419134.1 218528318 7118895 253192..253950 1 NC_011757.1 KEGG: mrd:Mrad2831_5718 hypothetical protein; hypothetical protein 253950 7118895 Mchl_0268 Methylobacterium extorquens CM4 hypothetical protein YP_002419134.1 253192 D 440085 CDS YP_002419135.1 218528319 7118896 253947..254333 1 NC_011757.1 KEGG: sth:STH2761 NrdR family transcriptional regulator; hypothetical protein 254333 7118896 Mchl_0269 Methylobacterium extorquens CM4 hypothetical protein YP_002419135.1 253947 D 440085 CDS YP_002419136.1 218528320 7118897 254501..254962 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_2438 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 254962 7118897 Mchl_0270 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002419136.1 254501 D 440085 CDS YP_002419137.1 218528321 7118898 255070..255783 1 NC_011757.1 hypothetical protein 255783 7118898 Mchl_0271 Methylobacterium extorquens CM4 hypothetical protein YP_002419137.1 255070 D 440085 CDS YP_002419138.1 218528322 7118899 complement(255988..258288) 1 NC_011757.1 KEGG: met:M446_2057 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; MHYT domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 258288 7118899 Mchl_0272 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002419138.1 255988 R 440085 CDS YP_002419139.1 218528323 7118900 complement(258518..258781) 1 NC_011757.1 KEGG: mrd:Mrad2831_0291 hypothetical protein; hypothetical protein 258781 7118900 Mchl_0273 Methylobacterium extorquens CM4 hypothetical protein YP_002419139.1 258518 R 440085 CDS YP_002419140.1 218528324 7118901 258869..259117 1 NC_011757.1 KEGG: mex:Mext_0103 hypothetical protein; hypothetical protein 259117 7118901 Mchl_0274 Methylobacterium extorquens CM4 hypothetical protein YP_002419140.1 258869 D 440085 CDS YP_002419141.1 218528325 7118902 259252..259470 1 NC_011757.1 KEGG: mrd:Mrad2831_5940 hypothetical protein; hypothetical protein 259470 7118902 Mchl_0275 Methylobacterium extorquens CM4 hypothetical protein YP_002419141.1 259252 D 440085 CDS YP_002419142.1 218528326 7118903 complement(259791..259931) 1 NC_011757.1 KEGG: mpo:Mpop_2771 hypothetical protein; hypothetical protein 259931 7118903 Mchl_0276 Methylobacterium extorquens CM4 hypothetical protein YP_002419142.1 259791 R 440085 CDS YP_002419143.1 218528327 7118904 260015..260167 1 NC_011757.1 hypothetical protein 260167 7118904 Mchl_0277 Methylobacterium extorquens CM4 hypothetical protein YP_002419143.1 260015 D 440085 CDS YP_002419144.1 218528328 7118905 260293..260931 1 NC_011757.1 KEGG: bph:Bphy_1890 hypothetical protein; hypothetical protein 260931 7118905 Mchl_0278 Methylobacterium extorquens CM4 hypothetical protein YP_002419144.1 260293 D 440085 CDS YP_002419145.1 218528329 7118906 260876..262954 1 NC_011757.1 PFAM: terminase GpA; KEGG: ecx:EcHS_A2094 phage terminase large subunit (GpA); terminase GpA 262954 7118906 Mchl_0279 Methylobacterium extorquens CM4 terminase GpA YP_002419145.1 260876 D 440085 CDS YP_002419146.1 218528330 7118907 262958..263212 1 NC_011757.1 hypothetical protein 263212 7118907 Mchl_0280 Methylobacterium extorquens CM4 hypothetical protein YP_002419146.1 262958 D 440085 CDS YP_002419147.1 218528331 7118908 263215..264834 1 NC_011757.1 TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: rso:RSc0857 bacteriophage-like protein; phage portal protein, lambda family 264834 7118908 Mchl_0281 Methylobacterium extorquens CM4 phage portal protein, lambda family YP_002419147.1 263215 D 440085 CDS YP_002419148.1 218528332 7118909 264831..265730 1 NC_011757.1 PFAM: peptidase S49; KEGG: rsq:Rsph17025_1752 peptidase S49; peptidase S49 265730 7118909 Mchl_0282 Methylobacterium extorquens CM4 peptidase S49 YP_002419148.1 264831 D 440085 CDS YP_002419149.1 218528333 7118910 265810..266394 1 NC_011757.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 266394 7118910 Mchl_0283 Methylobacterium extorquens CM4 hypothetical protein YP_002419149.1 265810 D 440085 CDS YP_002419150.1 218528334 7118911 266397..266777 1 NC_011757.1 KEGG: rso:RSc0859 bacteriophage-like protein; bacteriophage-like protein 266777 7118911 Mchl_0284 Methylobacterium extorquens CM4 bacteriophage-like protein YP_002419150.1 266397 D 440085 CDS YP_002419151.1 218528335 7118912 266781..267836 1 NC_011757.1 KEGG: rso:RSc0860 bacteriophage-like protein; bacteriophage-like protein 267836 7118912 Mchl_0285 Methylobacterium extorquens CM4 bacteriophage-like protein YP_002419151.1 266781 D 440085 CDS YP_002419152.1 218528336 7118913 267923..268201 1 NC_011757.1 hypothetical protein 268201 7118913 Mchl_0286 Methylobacterium extorquens CM4 hypothetical protein YP_002419152.1 267923 D 440085 CDS YP_002419153.1 218528337 7118914 268198..268563 1 NC_011757.1 KEGG: nwi:Nwi_0805 hypothetical protein; hypothetical protein 268563 7118914 Mchl_0287 Methylobacterium extorquens CM4 hypothetical protein YP_002419153.1 268198 D 440085 CDS YP_002419154.1 218528338 7118915 268560..269225 1 NC_011757.1 KEGG: nwi:Nwi_0802 hypothetical protein; hypothetical protein 269225 7118915 Mchl_0288 Methylobacterium extorquens CM4 hypothetical protein YP_002419154.1 268560 D 440085 CDS YP_002419155.1 218528339 7118916 269225..269659 1 NC_011757.1 KEGG: nwi:Nwi_0801 hypothetical protein; hypothetical protein 269659 7118916 Mchl_0289 Methylobacterium extorquens CM4 hypothetical protein YP_002419155.1 269225 D 440085 CDS YP_002419156.1 218528340 7118917 269684..270625 1 NC_011757.1 KEGG: nwi:Nwi_0800 hypothetical protein; hypothetical protein 270625 7118917 Mchl_0290 Methylobacterium extorquens CM4 hypothetical protein YP_002419156.1 269684 D 440085 CDS YP_002419157.1 218528341 7118918 270853..271272 1 NC_011757.1 KEGG: nwi:Nwi_0799 hypothetical protein; hypothetical protein 271272 7118918 Mchl_0291 Methylobacterium extorquens CM4 hypothetical protein YP_002419157.1 270853 D 440085 CDS YP_002419158.1 218528342 7118919 271326..271523 1 NC_011757.1 KEGG: nwi:Nwi_0798 hypothetical protein; hypothetical protein 271523 7118919 Mchl_0292 Methylobacterium extorquens CM4 hypothetical protein YP_002419158.1 271326 D 440085 CDS YP_002419159.1 218528343 7118920 271513..275007 1 NC_011757.1 KEGG: nwi:Nwi_0797 phage-related minor tail protein; hypothetical protein 275007 7118920 Mchl_0293 Methylobacterium extorquens CM4 hypothetical protein YP_002419159.1 271513 D 440085 CDS YP_002419160.1 218528344 7118921 275011..275385 1 NC_011757.1 KEGG: mpo:Mpop_2674 hypothetical protein; hypothetical protein 275385 7118921 Mchl_0294 Methylobacterium extorquens CM4 hypothetical protein YP_002419160.1 275011 D 440085 CDS YP_002419161.1 218528345 7118922 275390..275938 1 NC_011757.1 PFAM: Domain of unknown function DUF1833; KEGG: mag:amb0393 hypothetical protein; hypothetical protein 275938 7118922 Mchl_0295 Methylobacterium extorquens CM4 hypothetical protein YP_002419161.1 275390 D 440085 CDS YP_002419162.1 218528346 7118923 275935..276333 1 NC_011757.1 KEGG: mex:Mext_3535 NLP/P60 protein; NLP/P60 protein 276333 7118923 Mchl_0296 Methylobacterium extorquens CM4 NLP/P60 protein YP_002419162.1 275935 D 440085 CDS YP_002419163.1 218528347 7117044 complement(276361..276723) 1 NC_011757.1 KEGG: mex:Mext_3537 hypothetical protein; hypothetical protein 276723 7117044 Mchl_0297 Methylobacterium extorquens CM4 hypothetical protein YP_002419163.1 276361 R 440085 CDS YP_002419164.1 218528348 7118596 276953..281665 1 NC_011757.1 KEGG: mex:Mext_3534 hypothetical protein; hypothetical protein 281665 7118596 Mchl_0298 Methylobacterium extorquens CM4 hypothetical protein YP_002419164.1 276953 D 440085 CDS YP_002419165.1 218528349 7118597 281741..283072 1 NC_011757.1 KEGG: mrd:Mrad2831_4981 hypothetical protein; hypothetical protein 283072 7118597 Mchl_0299 Methylobacterium extorquens CM4 hypothetical protein YP_002419165.1 281741 D 440085 CDS YP_002419166.1 218528350 7118598 283072..283656 1 NC_011757.1 KEGG: azc:AZC_2161 hypothetical protein; hypothetical protein 283656 7118598 Mchl_0300 Methylobacterium extorquens CM4 hypothetical protein YP_002419166.1 283072 D 440085 CDS YP_002419167.1 218528351 7118599 283667..283963 1 NC_011757.1 hypothetical protein 283963 7118599 Mchl_0301 Methylobacterium extorquens CM4 hypothetical protein YP_002419167.1 283667 D 440085 CDS YP_002419168.1 218528352 7118600 complement(284057..284413) 1 NC_011757.1 KEGG: mpo:Mpop_3138 hypothetical protein; hypothetical protein 284413 7118600 Mchl_0302 Methylobacterium extorquens CM4 hypothetical protein YP_002419168.1 284057 R 440085 CDS YP_002419169.1 218528353 7118601 284581..285279 1 NC_011757.1 PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_4383 peptidoglycan binding domain-containing protein; peptidoglycan-binding protein 285279 7118601 Mchl_0303 Methylobacterium extorquens CM4 peptidoglycan-binding protein YP_002419169.1 284581 D 440085 CDS YP_002419170.1 218528354 7118602 285913..286476 1 NC_011757.1 KEGG: mex:Mext_4382 hypothetical protein; hypothetical protein 286476 7118602 Mchl_0304 Methylobacterium extorquens CM4 hypothetical protein YP_002419170.1 285913 D 440085 CDS YP_002419171.1 218528355 7118603 286490..287014 1 NC_011757.1 KEGG: xau:Xaut_3728 hypothetical protein; hypothetical protein 287014 7118603 Mchl_0305 Methylobacterium extorquens CM4 hypothetical protein YP_002419171.1 286490 D 440085 CDS YP_002419172.1 218528356 7118604 287014..287382 1 NC_011757.1 hypothetical protein 287382 7118604 Mchl_0306 Methylobacterium extorquens CM4 hypothetical protein YP_002419172.1 287014 D 440085 CDS YP_002419173.1 218528357 7118605 287382..287567 1 NC_011757.1 KEGG: mpo:Mpop_3761 hypothetical protein; hypothetical protein 287567 7118605 Mchl_0307 Methylobacterium extorquens CM4 hypothetical protein YP_002419173.1 287382 D 440085 CDS YP_002419174.1 218528358 7118606 287651..289276 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mrd:Mrad2831_2428 diguanylate cyclase/phosphodiesterase; diguanylate cyclase/phosphodiesterase 289276 7118606 Mchl_0308 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002419174.1 287651 D 440085 CDS YP_002419175.1 218528359 7118607 complement(289497..291206) 1 NC_011757.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: rpc:RPC_1770 cytidine/deoxycytidylate deaminase, zinc-binding region; zinc-binding CMP/dCMP deaminase 291206 7118607 Mchl_0309 Methylobacterium extorquens CM4 zinc-binding CMP/dCMP deaminase YP_002419175.1 289497 R 440085 CDS YP_002419176.1 218528360 7118608 291310..291483 1 NC_011757.1 hypothetical protein 291483 7118608 Mchl_0310 Methylobacterium extorquens CM4 hypothetical protein YP_002419176.1 291310 D 440085 CDS YP_002419177.1 218528361 7118609 complement(291544..291663) 1 NC_011757.1 hypothetical protein 291663 7118609 Mchl_0311 Methylobacterium extorquens CM4 hypothetical protein YP_002419177.1 291544 R 440085 CDS YP_002419178.1 218528362 7118610 complement(291676..291918) 1 NC_011757.1 KEGG: mex:Mext_0359 hypothetical protein; hypothetical protein 291918 7118610 Mchl_0312 Methylobacterium extorquens CM4 hypothetical protein YP_002419178.1 291676 R 440085 CDS YP_002419179.1 218528363 7118611 complement(291921..292175) 1 NC_011757.1 KEGG: mex:Mext_0360 hypothetical protein; hypothetical protein 292175 7118611 Mchl_0313 Methylobacterium extorquens CM4 hypothetical protein YP_002419179.1 291921 R 440085 CDS YP_002419180.1 218528364 7118612 292315..292770 1 NC_011757.1 PFAM: peptidase S24 and S26 domain protein; KEGG: mex:Mext_0361 peptidase S24/S26 domain-containing protein; peptidase S24 and S26 domain-containing protein 292770 7118612 Mchl_0314 Methylobacterium extorquens CM4 peptidase S24 and S26 domain-containing protein YP_002419180.1 292315 D 440085 CDS YP_002419181.1 218528365 7118613 292767..294098 1 NC_011757.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: mex:Mext_3517 DNA-directed DNA polymerase; DNA-directed DNA polymerase 294098 7118613 Mchl_0315 Methylobacterium extorquens CM4 DNA-directed DNA polymerase YP_002419181.1 292767 D 440085 CDS YP_002419182.1 218528366 7118615 complement(295697..296380) 1 NC_011757.1 PFAM: nuclease (SNase domain protein); KEGG: mex:Mext_0111 nuclease; nuclease 296380 7118615 Mchl_0317 Methylobacterium extorquens CM4 nuclease YP_002419182.1 295697 R 440085 CDS YP_002419183.1 218528367 7118616 complement(296675..296941) 1 NC_011757.1 KEGG: mpo:Mpop_4259 hypothetical protein; hypothetical protein 296941 7118616 Mchl_0318 Methylobacterium extorquens CM4 hypothetical protein YP_002419183.1 296675 R 440085 CDS YP_002419184.1 218528368 7118618 297241..298563 1 NC_011757.1 PFAM: ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_0275 recombination factor protein RarA; recombination factor protein RarA 298563 7118618 Mchl_0319 Methylobacterium extorquens CM4 recombination factor protein RarA YP_002419184.1 297241 D 440085 CDS YP_002419185.1 218528369 7118619 298599..300092 1 NC_011757.1 PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: mex:Mext_0276 carboxypeptidase Taq; carboxypeptidase Taq 300092 7118619 Mchl_0320 Methylobacterium extorquens CM4 carboxypeptidase Taq YP_002419185.1 298599 D 440085 CDS YP_002419186.1 218528370 7118620 300255..301502 1 NC_011757.1 KEGG: mex:Mext_0277 molecular chaperone, HSP70 class; molecular chaperone, HSP70 class 301502 7118620 Mchl_0321 Methylobacterium extorquens CM4 molecular chaperone, HSP70 class YP_002419186.1 300255 D 440085 CDS YP_002419187.1 218528371 7118621 301730..303136 1 NC_011757.1 KEGG: mex:Mext_0278 RluA family pseudouridine synthase; TIGRFAM: pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; pseudouridine synthase 303136 7118621 Mchl_0322 Methylobacterium extorquens CM4 pseudouridine synthase YP_002419187.1 301730 D 440085 CDS YP_002419188.1 218528372 7118622 303781..304482 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_0280 HAD family hydrolase; HAD-superfamily hydrolase 304482 7118622 Mchl_0323 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002419188.1 303781 D 440085 CDS YP_002419189.1 218528373 7118623 304543..305346 1 NC_011757.1 PFAM: ATP12 ATPase; KEGG: mex:Mext_0281 ATP12 ATPase; ATP12 ATPase 305346 7118623 Mchl_0324 Methylobacterium extorquens CM4 ATP12 ATPase YP_002419189.1 304543 D 440085 CDS YP_002419190.1 218528374 7118624 305518..305655 1 NC_011757.1 hypothetical protein 305655 7118624 Mchl_0325 Methylobacterium extorquens CM4 hypothetical protein YP_002419190.1 305518 D 440085 CDS YP_002419191.1 218528375 7118625 305940..307472 1 NC_011757.1 PFAM: carboxyl transferase; KEGG: mex:Mext_0282 carboxyl transferase; carboxyl transferase 307472 7118625 Mchl_0326 Methylobacterium extorquens CM4 carboxyl transferase YP_002419191.1 305940 D 440085 CDS YP_002419192.1 218528376 7118626 complement(307534..308088) 1 NC_011757.1 KEGG: mex:Mext_0283 hypothetical protein; hypothetical protein 308088 7118626 Mchl_0327 Methylobacterium extorquens CM4 hypothetical protein YP_002419192.1 307534 R 440085 CDS YP_002419193.1 218528377 7118628 308525..309172 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_0284 regulatory protein TetR; TetR family transcriptional regulator 309172 7118628 Mchl_0328 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002419193.1 308525 D 440085 CDS YP_002419194.1 218528378 7118629 309206..310225 1 NC_011757.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 310225 7118629 Mchl_0329 Methylobacterium extorquens CM4 ketol-acid reductoisomerase YP_002419194.1 309206 D 440085 CDS YP_002419195.1 218528379 7118630 310393..311046 1 NC_011757.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mex:Mext_0286 pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 311046 7118630 Mchl_0330 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002419195.1 310393 D 440085 CDS YP_002419196.1 218528380 7118631 311158..311982 1 NC_011757.1 KEGG: mex:Mext_0287 hypothetical protein; hypothetical protein 311982 7118631 Mchl_0331 Methylobacterium extorquens CM4 hypothetical protein YP_002419196.1 311158 D 440085 CDS YP_002419197.1 218528381 7118632 complement(312055..313353) 1 NC_011757.1 TIGRFAM: crotonyl-CoA reductase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_0288 crotonyl-CoA reductase; crotonyl-CoA reductase 313353 7118632 Mchl_0332 Methylobacterium extorquens CM4 crotonyl-CoA reductase YP_002419197.1 312055 R 440085 CDS YP_002419198.1 218528382 7118633 complement(313534..315006) 1 NC_011757.1 PFAM: catalase; KEGG: mex:Mext_0289 catalase; catalase 315006 7118633 Mchl_0333 Methylobacterium extorquens CM4 catalase YP_002419198.1 313534 R 440085 CDS YP_002419199.1 218528383 7118634 315373..317439 1 NC_011757.1 KEGG: mex:Mext_0290 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; methylmalonyl-CoA mutase, large subunit 317439 7118634 Mchl_0334 Methylobacterium extorquens CM4 methylmalonyl-CoA mutase, large subunit YP_002419199.1 315373 D 440085 CDS YP_002419200.1 218528384 7118635 complement(317549..318235) 1 NC_011757.1 KEGG: mex:Mext_0291 hypothetical protein; hypothetical protein 318235 7118635 Mchl_0335 Methylobacterium extorquens CM4 hypothetical protein YP_002419200.1 317549 R 440085 CDS YP_002419201.1 218528385 7118636 complement(318532..319278) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; KEGG: mex:Mext_0292 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 319278 7118636 Mchl_0336 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419201.1 318532 R 440085 CDS YP_002419202.1 218528386 7118637 319387..319716 1 NC_011757.1 SMART: regulatory protein ArsR; KEGG: mex:Mext_0293 regulatory protein ArsR; regulatory protein ArsR 319716 7118637 Mchl_0337 Methylobacterium extorquens CM4 regulatory protein ArsR YP_002419202.1 319387 D 440085 CDS YP_002419203.1 218528387 7118638 319868..320929 1 NC_011757.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 320929 7118638 Mchl_0338 Methylobacterium extorquens CM4 tryptophanyl-tRNA synthetase YP_002419203.1 319868 D 440085 CDS YP_002419204.1 218528388 7118639 complement(321045..321218) 1 NC_011757.1 KEGG: mex:Mext_0295 hypothetical protein; hypothetical protein 321218 7118639 Mchl_0339 Methylobacterium extorquens CM4 hypothetical protein YP_002419204.1 321045 R 440085 CDS YP_002419205.1 218528389 7118640 321391..321996 1 NC_011757.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 321996 leuD 7118640 leuD Methylobacterium extorquens CM4 isopropylmalate isomerase small subunit YP_002419205.1 321391 D 440085 CDS YP_002419206.1 218528390 7118641 complement(322004..322621) 1 NC_011757.1 PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: mex:Mext_0297 peptidase C15 pyroglutamyl peptidase I; peptidase C15 pyroglutamyl peptidase I 322621 7118641 Mchl_0341 Methylobacterium extorquens CM4 peptidase C15 pyroglutamyl peptidase I YP_002419206.1 322004 R 440085 CDS YP_002419207.1 218528391 7118642 complement(322618..323607) 1 NC_011757.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transporters, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transporter ATPase 323607 7118642 Mchl_0342 Methylobacterium extorquens CM4 arginine/ornithine transporter ATPase YP_002419207.1 322618 R 440085 CDS YP_002419208.1 218528392 7118643 323754..324788 1 NC_011757.1 PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: mex:Mext_0299 protein of unknown function DUF900 hydrolase family protein; hypothetical protein 324788 7118643 Mchl_0343 Methylobacterium extorquens CM4 hypothetical protein YP_002419208.1 323754 D 440085 CDS YP_002419209.1 218528393 7118644 324974..325321 1 NC_011757.1 KEGG: mex:Mext_0300 hypothetical protein; hypothetical protein 325321 7118644 Mchl_0344 Methylobacterium extorquens CM4 hypothetical protein YP_002419209.1 324974 D 440085 CDS YP_002419210.1 218528394 7118645 complement(325399..327279) 1 NC_011757.1 PFAM: peptidase S15; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: mex:Mext_0301 peptidase S9 prolyl oligopeptidase; peptidase S9 prolyl oligopeptidase active site domain-containing protein 327279 7118645 Mchl_0345 Methylobacterium extorquens CM4 peptidase S9 prolyl oligopeptidase active site domain-containing protein YP_002419210.1 325399 R 440085 CDS YP_002419211.1 218528395 7118646 complement(327348..328265) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_0302 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 328265 7118646 Mchl_0346 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002419211.1 327348 R 440085 CDS YP_002419212.1 218528396 7118647 328607..328861 1 NC_011757.1 KEGG: mex:Mext_0303 hypothetical protein; hypothetical protein 328861 7118647 Mchl_0347 Methylobacterium extorquens CM4 hypothetical protein YP_002419212.1 328607 D 440085 CDS YP_002419213.1 218528397 7118648 328993..330240 1 NC_011757.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: mex:Mext_0304 nuclease SbcCD, D subunit; nuclease SbcCD subunit D 330240 7118648 Mchl_0348 Methylobacterium extorquens CM4 nuclease SbcCD subunit D YP_002419213.1 328993 D 440085 CDS YP_002419214.1 218528398 7118649 330252..333998 1 NC_011757.1 PFAM: SMC domain protein; KEGG: mex:Mext_0305 SMC domain-containing protein; SMC domain-containing protein 333998 7118649 Mchl_0349 Methylobacterium extorquens CM4 SMC domain-containing protein YP_002419214.1 330252 D 440085 CDS YP_002419215.1 218528399 7118650 334260..335519 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0306 major facilitator transporter; major facilitator superfamily protein 335519 7118650 Mchl_0350 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419215.1 334260 D 440085 CDS YP_002419216.1 218528400 7118651 complement(335602..336369) 1 NC_011757.1 KEGG: mex:Mext_0307 competence protein F; competence protein F 336369 7118651 Mchl_0351 Methylobacterium extorquens CM4 competence protein F YP_002419216.1 335602 R 440085 CDS YP_002419217.1 218528401 7118652 complement(336456..336626) 1 NC_011757.1 KEGG: mex:Mext_0308 hypothetical protein; hypothetical protein 336626 7118652 Mchl_0352 Methylobacterium extorquens CM4 hypothetical protein YP_002419217.1 336456 R 440085 CDS YP_002419218.1 218528402 7118653 336830..337723 1 NC_011757.1 PFAM: methyltransferase type 11; KEGG: mex:Mext_0309 methyltransferase type 11; type 11 methyltransferase 337723 7118653 Mchl_0353 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002419218.1 336830 D 440085 CDS YP_002419219.1 218528403 7118654 337720..338076 1 NC_011757.1 PFAM: protein of unknown function DUF427; KEGG: mex:Mext_0310 hypothetical protein; hypothetical protein 338076 7118654 Mchl_0354 Methylobacterium extorquens CM4 hypothetical protein YP_002419219.1 337720 D 440085 CDS YP_002419220.1 218528404 7118655 complement(338085..339626) 1 NC_011757.1 KEGG: mex:Mext_0311 hypothetical protein; hypothetical protein 339626 7118655 Mchl_0355 Methylobacterium extorquens CM4 hypothetical protein YP_002419220.1 338085 R 440085 CDS YP_002419221.1 218528405 7118656 complement(339658..340074) 1 NC_011757.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: mex:Mext_0312 mutator MutT protein; mutator MutT protein 340074 7118656 Mchl_0356 Methylobacterium extorquens CM4 mutator MutT protein YP_002419221.1 339658 R 440085 CDS YP_002419222.1 218528406 7118657 complement(340071..340793) 1 NC_011757.1 PFAM: protein of unknown function DUF541; KEGG: mex:Mext_0313 hypothetical protein; hypothetical protein 340793 7118657 Mchl_0357 Methylobacterium extorquens CM4 hypothetical protein YP_002419222.1 340071 R 440085 CDS YP_002419223.1 218528407 7118658 complement(340790..342034) 1 NC_011757.1 KEGG: mex:Mext_0314 arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: arginine biosynthesis protein ArgJ; arginine biosynthesis bifunctional protein ArgJ 342034 7118658 Mchl_0358 Methylobacterium extorquens CM4 arginine biosynthesis bifunctional protein ArgJ YP_002419223.1 340790 R 440085 CDS YP_002419224.1 218528408 7118659 342415..342885 1 NC_011757.1 KEGG: mex:Mext_0315 sensor histidine kinase; sensor histidine kinase 342885 7118659 Mchl_0359 Methylobacterium extorquens CM4 sensor histidine kinase YP_002419224.1 342415 D 440085 CDS YP_002419225.1 218528409 7118660 342978..343532 1 NC_011757.1 PFAM: glutathione peroxidase; KEGG: mex:Mext_0316 glutathione peroxidase; glutathione peroxidase 343532 7118660 Mchl_0360 Methylobacterium extorquens CM4 glutathione peroxidase YP_002419225.1 342978 D 440085 CDS YP_002419226.1 218528410 7118661 complement(343549..343815) 1 NC_011757.1 KEGG: mrd:Mrad2831_2681 hypothetical protein; hypothetical protein 343815 7118661 Mchl_0361 Methylobacterium extorquens CM4 hypothetical protein YP_002419226.1 343549 R 440085 CDS YP_002419227.1 218528411 7118662 343875..344102 1 NC_011757.1 KEGG: mex:Mext_0317 hypothetical protein; hypothetical protein 344102 7118662 Mchl_0362 Methylobacterium extorquens CM4 hypothetical protein YP_002419227.1 343875 D 440085 CDS YP_002419228.1 218528412 7118663 344293..344535 1 NC_011757.1 KEGG: mex:Mext_0318 hypothetical protein; hypothetical protein 344535 7118663 Mchl_0363 Methylobacterium extorquens CM4 hypothetical protein YP_002419228.1 344293 D 440085 CDS YP_002419229.1 218528413 7118664 complement(344542..347649) 1 NC_011757.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 347649 7118664 Mchl_0364 Methylobacterium extorquens CM4 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002419229.1 344542 R 440085 CDS YP_002419230.1 218528414 7118665 complement(347737..351264) 1 NC_011757.1 KEGG: mex:Mext_0320 hypothetical protein; hypothetical protein 351264 7118665 Mchl_0365 Methylobacterium extorquens CM4 hypothetical protein YP_002419230.1 347737 R 440085 CDS YP_002419231.1 218528415 7118666 complement(351425..351676) 1 NC_011757.1 KEGG: mex:Mext_0321 hypothetical protein; hypothetical protein 351676 7118666 Mchl_0366 Methylobacterium extorquens CM4 hypothetical protein YP_002419231.1 351425 R 440085 CDS YP_002419232.1 218528416 7118667 351792..354179 1 NC_011757.1 PFAM: UvrD/REP helicase; KEGG: mex:Mext_0322 UvrD/REP helicase; UvrD/REP helicase 354179 7118667 Mchl_0367 Methylobacterium extorquens CM4 UvrD/REP helicase YP_002419232.1 351792 D 440085 CDS YP_002419233.1 218528417 7118668 354576..355292 1 NC_011757.1 PFAM: PhoH family protein; KEGG: mex:Mext_0323 PhoH family protein; PhoH family protein 355292 7118668 Mchl_0368 Methylobacterium extorquens CM4 PhoH family protein YP_002419233.1 354576 D 440085 CDS YP_002419234.1 218528418 7118669 complement(355363..356103) 1 NC_011757.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: mex:Mext_0324 MIP family channel protein; MIP family channel protein 356103 7118669 Mchl_0369 Methylobacterium extorquens CM4 MIP family channel protein YP_002419234.1 355363 R 440085 CDS YP_002419235.1 218528419 7118670 complement(356475..357368) 1 NC_011757.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: mex:Mext_0325 exonuclease RNase T and DNA polymerase III; exonuclease RNase T and DNA polymerase III 357368 7118670 Mchl_0370 Methylobacterium extorquens CM4 exonuclease RNase T and DNA polymerase III YP_002419235.1 356475 R 440085 CDS YP_002419236.1 218528420 7118671 357519..358733 1 NC_011757.1 KEGG: mpo:Mpop_0402 bicupin, oxalate decarboxylase family; TIGRFAM: bicupin, oxalate decarboxylase family; PFAM: Cupin domain protein; cupin; bicupin, oxalate decarboxylase family 358733 7118671 Mchl_0371 Methylobacterium extorquens CM4 bicupin, oxalate decarboxylase family YP_002419236.1 357519 D 440085 CDS YP_002419237.1 218528421 7118672 complement(358739..361696) 1 NC_011757.1 PFAM: glutamate-ammonia ligase adenylyltransferase; GlnD PII-uridylyltransferase; KEGG: mex:Mext_0326 (glutamate--ammonia-ligase) adenylyltransferase; (glutamate--ammonia-ligase) adenylyltransferase 361696 7118672 Mchl_0372 Methylobacterium extorquens CM4 (glutamate--ammonia-ligase) adenylyltransferase YP_002419237.1 358739 R 440085 CDS YP_002419238.1 218528422 7118673 complement(361938..362615) 1 NC_011757.1 KEGG: mex:Mext_0327 hypothetical protein; hypothetical protein 362615 7118673 Mchl_0373 Methylobacterium extorquens CM4 hypothetical protein YP_002419238.1 361938 R 440085 CDS YP_002419239.1 218528423 7118674 363052..363267 1 NC_011757.1 KEGG: mpo:Mpop_0404 hypothetical protein; hypothetical protein 363267 7118674 Mchl_0374 Methylobacterium extorquens CM4 hypothetical protein YP_002419239.1 363052 D 440085 CDS YP_002419240.1 218528424 7118675 complement(363275..364705) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_0328 ATPase domain-containing protein; histidine kinase 364705 7118675 Mchl_0375 Methylobacterium extorquens CM4 histidine kinase YP_002419240.1 363275 R 440085 CDS YP_002419241.1 218528425 7118676 complement(364702..365400) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_0329 response regulator receiver; transcriptional regulator 365400 7118676 Mchl_0376 Methylobacterium extorquens CM4 transcriptional regulator YP_002419241.1 364702 R 440085 CDS YP_002419242.1 218528426 7115100 complement(365427..365936) 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_0330 OsmC family protein; OsmC family protein 365936 7115100 Mchl_0377 Methylobacterium extorquens CM4 OsmC family protein YP_002419242.1 365427 R 440085 CDS YP_002419243.1 218528427 7116385 complement(366012..366791) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_0331 ABC transporter; ABC transporter 366791 7116385 Mchl_0378 Methylobacterium extorquens CM4 ABC transporter YP_002419243.1 366012 R 440085 CDS YP_002419244.1 218528428 7116386 complement(366799..367638) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0332 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 367638 7116386 Mchl_0379 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002419244.1 366799 R 440085 CDS YP_002419245.1 218528429 7116388 complement(368340..369314) 1 NC_011757.1 TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: NMT1/THI5 like domain protein; KEGG: mex:Mext_0334 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 369314 7116388 Mchl_0381 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002419245.1 368340 R 440085 CDS YP_002419246.1 218528430 7116389 369474..372260 1 NC_011757.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 372260 7116389 Mchl_0382 Methylobacterium extorquens CM4 PII uridylyl-transferase YP_002419246.1 369474 D 440085 CDS YP_002419247.1 218528431 7116390 372352..372960 1 NC_011757.1 PFAM: GrpE protein; KEGG: mex:Mext_0336 ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 372960 7116390 Mchl_0383 Methylobacterium extorquens CM4 ribulose-phosphate 3-epimerase YP_002419247.1 372352 D 440085 CDS YP_002419248.1 218528432 7116391 complement(373029..373886) 1 NC_011757.1 PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mex:Mext_0339 prephenate dehydratase; prephenate dehydratase 373886 7116391 Mchl_0384 Methylobacterium extorquens CM4 prephenate dehydratase YP_002419248.1 373029 R 440085 CDS YP_002419249.1 218528433 7116392 complement(373903..374646) 1 NC_011757.1 KEGG: mex:Mext_0340 3-deoxy-D-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; 3-deoxy-D-manno-octulosonate cytidylyltransferase 374646 7116392 Mchl_0385 Methylobacterium extorquens CM4 3-deoxy-D-manno-octulosonate cytidylyltransferase YP_002419249.1 373903 R 440085 CDS YP_002419250.1 218528434 7116393 374954..375871 1 NC_011757.1 PFAM: cytochrome C class I; KEGG: mex:Mext_0341 cytochrome c class I; cytochrome C class I 375871 7116393 Mchl_0386 Methylobacterium extorquens CM4 cytochrome C class I YP_002419250.1 374954 D 440085 CDS YP_002419251.1 218528435 7116394 376044..377957 1 NC_011757.1 PFAM: extracellular solute-binding protein family 5; KEGG: mex:Mext_0342 extracellular solute-binding protein; family 5 extracellular solute-binding protein 377957 7116394 Mchl_0387 Methylobacterium extorquens CM4 family 5 extracellular solute-binding protein YP_002419251.1 376044 D 440085 CDS YP_002419252.1 218528436 7116395 377954..379828 1 NC_011757.1 PFAM: extracellular solute-binding protein family 5; KEGG: mex:Mext_0343 extracellular solute-binding protein; family 5 extracellular solute-binding protein 379828 7116395 Mchl_0388 Methylobacterium extorquens CM4 family 5 extracellular solute-binding protein YP_002419252.1 377954 D 440085 CDS YP_002419253.1 218528437 7116396 379838..380935 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0344 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 380935 7116396 Mchl_0389 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002419253.1 379838 D 440085 CDS YP_002419254.1 218528438 7116397 381004..381507 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_0345 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 381507 7116397 Mchl_0390 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002419254.1 381004 D 440085 CDS YP_002419255.1 218528439 7116398 381621..383153 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_0346 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 383153 7116398 Mchl_0391 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002419255.1 381621 D 440085 CDS YP_002419256.1 218528440 7116399 383214..383996 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_0347 glycosyl transferase; family 2 glycosyl transferase 383996 7116399 Mchl_0392 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419256.1 383214 D 440085 CDS YP_002419257.1 218528441 7116401 384610..386070 1 NC_011757.1 KEGG: mpo:Mpop_1057 transcriptional regulator, LuxR family; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; LuxR family transcriptional regulator 386070 7116401 Mchl_0393 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002419257.1 384610 D 440085 CDS YP_002419258.1 218528442 7116402 386166..386321 1 NC_011757.1 KEGG: mpo:Mpop_1056 hypothetical protein; hypothetical protein 386321 7116402 Mchl_0394 Methylobacterium extorquens CM4 hypothetical protein YP_002419258.1 386166 D 440085 CDS YP_002419259.1 218528443 7116403 386380..386721 1 NC_011757.1 PFAM: CsbD family protein; KEGG: mex:Mext_0364 CsbD family protein; CsbD family protein 386721 7116403 Mchl_0395 Methylobacterium extorquens CM4 CsbD family protein YP_002419259.1 386380 D 440085 CDS YP_002419260.1 218528444 7116404 386766..387677 1 NC_011757.1 KEGG: mex:Mext_0365 hypothetical protein; hypothetical protein 387677 7116404 Mchl_0396 Methylobacterium extorquens CM4 hypothetical protein YP_002419260.1 386766 D 440085 CDS YP_002419261.1 218528445 7116405 387768..387971 1 NC_011757.1 PFAM: CsbD family protein; KEGG: mex:Mext_0366 CsbD family protein; CsbD family protein 387971 7116405 Mchl_0397 Methylobacterium extorquens CM4 CsbD family protein YP_002419261.1 387768 D 440085 CDS YP_002419262.1 218528446 7116406 388046..388429 1 NC_011757.1 KEGG: mex:Mext_0367 CsbD family protein; CsbD family protein 388429 7116406 Mchl_0398 Methylobacterium extorquens CM4 CsbD family protein YP_002419262.1 388046 D 440085 CDS YP_002419263.1 218528447 7116407 388453..388557 1 NC_011757.1 KEGG: mpo:Mpop_1051 hypothetical protein; hypothetical protein 388557 7116407 Mchl_0399 Methylobacterium extorquens CM4 hypothetical protein YP_002419263.1 388453 D 440085 CDS YP_002419264.1 218528448 7116408 complement(388650..389570) 1 NC_011757.1 PFAM: protein of unknown function UPF0187; KEGG: mex:Mext_0368 hypothetical protein; hypothetical protein 389570 7116408 Mchl_0400 Methylobacterium extorquens CM4 hypothetical protein YP_002419264.1 388650 R 440085 CDS YP_002419265.1 218528449 7116409 complement(389581..390756) 1 NC_011757.1 TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mex:Mext_0369 acetylornithine deacetylase (ArgE); acetylornithine deacetylase ArgE 390756 7116409 Mchl_0401 Methylobacterium extorquens CM4 acetylornithine deacetylase ArgE YP_002419265.1 389581 R 440085 CDS YP_002419266.1 218528450 7116410 complement(390753..391145) 1 NC_011757.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 391145 apaG 7116410 apaG Methylobacterium extorquens CM4 ApaG protein YP_002419266.1 390753 R 440085 CDS YP_002419267.1 218528451 7116411 391313..391762 1 NC_011757.1 KEGG: mex:Mext_0371 hypothetical protein; hypothetical protein 391762 7116411 Mchl_0403 Methylobacterium extorquens CM4 hypothetical protein YP_002419267.1 391313 D 440085 CDS YP_002419268.1 218528452 7116412 391759..392877 1 NC_011757.1 Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 392877 7116412 Mchl_0404 Methylobacterium extorquens CM4 2'-deoxycytidine 5'-triphosphate deaminase YP_002419268.1 391759 D 440085 CDS YP_002419269.1 218528453 7116413 complement(392925..393812) 1 NC_011757.1 PFAM: formate/nitrite transporter; KEGG: mex:Mext_0373 transporter, YfdC-like protein; formate/nitrite transporter 393812 7116413 Mchl_0405 Methylobacterium extorquens CM4 formate/nitrite transporter YP_002419269.1 392925 R 440085 CDS YP_002419270.1 218528454 7116414 complement(393924..394661) 1 NC_011757.1 PFAM: molybdopterin binding domain; KEGG: mex:Mext_0374 molybdopterin binding domain-containing protein; molybdopterin binding domain 394661 7116414 Mchl_0406 Methylobacterium extorquens CM4 molybdopterin binding domain YP_002419270.1 393924 R 440085 CDS YP_002419271.1 218528455 7116415 394745..395491 1 NC_011757.1 PFAM: sugar fermentation stimulation protein; KEGG: mex:Mext_0375 sugar fermentation stimulation protein; sugar fermentation stimulation protein 395491 7116415 Mchl_0407 Methylobacterium extorquens CM4 sugar fermentation stimulation protein YP_002419271.1 394745 D 440085 CDS YP_002419272.1 218528456 7116416 complement(395448..396389) 1 NC_011757.1 TIGRFAM: methyltransferase FkbM family; KEGG: mex:Mext_0376 FkbM family methyltransferase; FkbM family methyltransferase 396389 7116416 Mchl_0408 Methylobacterium extorquens CM4 FkbM family methyltransferase YP_002419272.1 395448 R 440085 CDS YP_002419273.1 218528457 7116417 396433..397209 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_0377 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 397209 7116417 Mchl_0409 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002419273.1 396433 D 440085 CDS YP_002419274.1 218528458 7116418 397348..397812 1 NC_011757.1 KEGG: mex:Mext_0378 hypothetical protein; hypothetical protein 397812 7116418 Mchl_0410 Methylobacterium extorquens CM4 hypothetical protein YP_002419274.1 397348 D 440085 CDS YP_002419275.1 218528459 7116419 complement(397836..398615) 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_0379 ABC-2 type transporter; ABC transporter 398615 7116419 Mchl_0411 Methylobacterium extorquens CM4 ABC transporter YP_002419275.1 397836 R 440085 CDS YP_002419276.1 218528460 7116420 complement(398612..399538) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_0380 ABC transporter; ABC transporter 399538 7116420 Mchl_0412 Methylobacterium extorquens CM4 ABC transporter YP_002419276.1 398612 R 440085 CDS YP_002419277.1 218528461 7116421 complement(399859..401856) 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mex:Mext_0381 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 401856 7116421 Mchl_0413 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002419277.1 399859 R 440085 CDS YP_002419278.1 218528462 7116422 402039..402797 1 NC_011757.1 KEGG: mex:Mext_0382 hypothetical protein; hypothetical protein 402797 7116422 Mchl_0414 Methylobacterium extorquens CM4 hypothetical protein YP_002419278.1 402039 D 440085 CDS YP_002419279.1 218528463 7116423 402794..403360 1 NC_011757.1 KEGG: mex:Mext_0383 hypothetical protein; hypothetical protein 403360 7116423 Mchl_0415 Methylobacterium extorquens CM4 hypothetical protein YP_002419279.1 402794 D 440085 CDS YP_002419280.1 218528464 7116424 403357..404367 1 NC_011757.1 KEGG: mex:Mext_0384 hypothetical protein; hypothetical protein 404367 7116424 Mchl_0416 Methylobacterium extorquens CM4 hypothetical protein YP_002419280.1 403357 D 440085 CDS YP_002419281.1 218528465 7116425 404376..404894 1 NC_011757.1 KEGG: mex:Mext_0385 molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein A 404894 7116425 Mchl_0417 Methylobacterium extorquens CM4 molybdopterin-guanine dinucleotide biosynthesis protein A YP_002419281.1 404376 D 440085 CDS YP_002419282.1 218528466 7116426 404891..405601 1 NC_011757.1 KEGG: mex:Mext_0386 hypothetical protein; hypothetical protein 405601 7116426 Mchl_0418 Methylobacterium extorquens CM4 hypothetical protein YP_002419282.1 404891 D 440085 CDS YP_002419283.1 218528467 7116427 405689..406324 1 NC_011757.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: mex:Mext_0387 cytoplasmic chaperone TorD family protein; cytoplasmic chaperone TorD family protein 406324 7116427 Mchl_0419 Methylobacterium extorquens CM4 cytoplasmic chaperone TorD family protein YP_002419283.1 405689 D 440085 CDS YP_002419284.1 218528468 7116428 406401..406646 1 NC_011757.1 TIGRFAM: formate dehydrogenase region TAT target; KEGG: mex:Mext_0388 formate dehydrogenase region TAT target; formate dehydrogenase region TAT target 406646 7116428 Mchl_0420 Methylobacterium extorquens CM4 formate dehydrogenase region TAT target YP_002419284.1 406401 D 440085 CDS YP_002419285.1 218528469 7116429 406654..409596 1 NC_011757.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mex:Mext_0389 molybdopterin oxidoreductase; molybdopterin oxidoreductase 409596 7116429 Mchl_0421 Methylobacterium extorquens CM4 molybdopterin oxidoreductase YP_002419285.1 406654 D 440085 CDS YP_002419286.1 218528470 7116430 409614..410210 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mpo:Mpop_0458 4Fe-4S ferredoxin iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 410210 7116430 Mchl_0422 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002419286.1 409614 D 440085 CDS YP_002419287.1 218528471 7116431 410279..411316 1 NC_011757.1 TIGRFAM: formate dehydrogenase, subunit gamma; KEGG: mex:Mext_0391 formate dehydrogenase, subunit gamma; formate dehydrogenase subunit gamma 411316 7116431 Mchl_0423 Methylobacterium extorquens CM4 formate dehydrogenase subunit gamma YP_002419287.1 410279 D 440085 CDS YP_002419288.1 218528472 7116432 411412..411651 1 NC_011757.1 KEGG: mex:Mext_0392 hypothetical protein; hypothetical protein 411651 7116432 Mchl_0424 Methylobacterium extorquens CM4 hypothetical protein YP_002419288.1 411412 D 440085 CDS YP_002419289.1 218528473 7116433 411696..412313 1 NC_011757.1 KEGG: mex:Mext_0393 hypothetical protein; hypothetical protein 412313 7116433 Mchl_0425 Methylobacterium extorquens CM4 hypothetical protein YP_002419289.1 411696 D 440085 CDS YP_002419290.1 218528474 7116434 complement(412351..412944) 1 NC_011757.1 KEGG: mex:Mext_0394 hypothetical protein; hypothetical protein 412944 7116434 Mchl_0426 Methylobacterium extorquens CM4 hypothetical protein YP_002419290.1 412351 R 440085 CDS YP_002419291.1 218528475 7116435 413264..413578 1 NC_011757.1 KEGG: mpo:Mpop_0463 hypothetical protein; hypothetical protein 413578 7116435 Mchl_0427 Methylobacterium extorquens CM4 hypothetical protein YP_002419291.1 413264 D 440085 CDS YP_002419292.1 218528476 7116436 413575..414210 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_0395 regulatory protein TetR; TetR family transcriptional regulator 414210 7116436 Mchl_0428 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002419292.1 413575 D 440085 CDS YP_002419293.1 218528477 7116437 414207..415448 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_0396 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 415448 7116437 Mchl_0429 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002419293.1 414207 D 440085 CDS YP_002419294.1 218528478 7116438 415498..418593 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_0397 acriflavin resistance protein; acriflavin resistance protein 418593 7116438 Mchl_0430 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002419294.1 415498 D 440085 CDS YP_002419295.1 218528479 7116439 complement(418831..419109) 1 NC_011757.1 KEGG: mex:Mext_0398 hypothetical protein; hypothetical protein 419109 7116439 Mchl_0431 Methylobacterium extorquens CM4 hypothetical protein YP_002419295.1 418831 R 440085 CDS YP_002419296.1 218528480 7116440 complement(419240..420331) 1 NC_011757.1 negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 420331 hrcA 7116440 hrcA Methylobacterium extorquens CM4 heat-inducible transcription repressor YP_002419296.1 419240 R 440085 CDS YP_002419297.1 218528481 7116441 420570..420872 1 NC_011757.1 KEGG: mex:Mext_0400 hypothetical protein; hypothetical protein 420872 7116441 Mchl_0433 Methylobacterium extorquens CM4 hypothetical protein YP_002419297.1 420570 D 440085 CDS YP_002419298.1 218528482 7116442 421037..421750 1 NC_011757.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 421750 rph 7116442 rph Methylobacterium extorquens CM4 ribonuclease PH YP_002419298.1 421037 D 440085 CDS YP_002419299.1 218528483 7116443 421747..422382 1 NC_011757.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 422382 7116443 Mchl_0435 Methylobacterium extorquens CM4 deoxyribonucleotide triphosphate pyrophosphatase YP_002419299.1 421747 D 440085 CDS YP_002419300.1 218528484 7116444 422614..423810 1 NC_011757.1 KEGG: mex:Mext_0403 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; oxygen-independent coproporphyrinogen III oxidase 423810 7116444 Mchl_0436 Methylobacterium extorquens CM4 oxygen-independent coproporphyrinogen III oxidase YP_002419300.1 422614 D 440085 CDS YP_002419301.1 218528485 7116445 complement(423815..425020) 1 NC_011757.1 KEGG: mex:Mext_0404 extracellular ligand-binding receptor; extracellular ligand-binding receptor 425020 7116445 Mchl_0437 Methylobacterium extorquens CM4 extracellular ligand-binding receptor YP_002419301.1 423815 R 440085 CDS YP_002419302.1 218528486 7116446 425141..426091 1 NC_011757.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mex:Mext_0405 uroporphyrin-III C/tetrapyrrole methyltransferase; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 426091 7116446 Mchl_0438 Methylobacterium extorquens CM4 uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_002419302.1 425141 D 440085 CDS YP_002419303.1 218528487 7116447 426075..426461 1 NC_011757.1 PFAM: protein of unknown function UPF0102; KEGG: mex:Mext_0406 hypothetical protein; hypothetical protein 426461 7116447 Mchl_0439 Methylobacterium extorquens CM4 hypothetical protein YP_002419303.1 426075 D 440085 CDS YP_002419304.1 218528488 7116448 complement(426491..426883) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_0407 response regulator receiver; response regulator receiver protein 426883 7116448 Mchl_0440 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419304.1 426491 R 440085 CDS YP_002419305.1 218528489 7116449 427176..428087 1 NC_011757.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; KEGG: mex:Mext_0408 substrate-binding region of ABC-type glycine betaine transporter; glycine betaine ABC transporter substrate-binding protein 428087 7116449 Mchl_0441 Methylobacterium extorquens CM4 glycine betaine ABC transporter substrate-binding protein YP_002419305.1 427176 D 440085 CDS YP_002419306.1 218528490 7116450 428084..429226 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0409 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 429226 7116450 Mchl_0442 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002419306.1 428084 D 440085 CDS YP_002419307.1 218528491 7116451 429223..429951 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0410 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 429951 7116451 Mchl_0443 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002419307.1 429223 D 440085 CDS YP_002419308.1 218528492 7116452 complement(429958..431067) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_0411 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 431067 7116452 Mchl_0444 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002419308.1 429958 R 440085 CDS YP_002419309.1 218528493 7116453 complement(431174..432091) 1 NC_011757.1 PFAM: Extensin family protein; KEGG: mex:Mext_0412 extensin family protein; Extensin family protein 432091 7116453 Mchl_0445 Methylobacterium extorquens CM4 Extensin family protein YP_002419309.1 431174 R 440085 CDS YP_002419310.1 218528494 7116454 432290..434389 1 NC_011757.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: mex:Mext_0413 peptidyl-dipeptidase DCP; peptidyl-dipeptidase Dcp 434389 7116454 Mchl_0446 Methylobacterium extorquens CM4 peptidyl-dipeptidase Dcp YP_002419310.1 432290 D 440085 CDS YP_002419311.1 218528495 7116455 complement(434499..436172) 1 NC_011757.1 PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: mex:Mext_0414 formate--tetrahydrofolate ligase; formate--tetrahydrofolate ligase 436172 7116455 Mchl_0447 Methylobacterium extorquens CM4 formate--tetrahydrofolate ligase YP_002419311.1 434499 R 440085 CDS YP_002419312.1 218528496 7116456 complement(436414..436635) 1 NC_011757.1 PFAM: Heavy metal transport/detoxification protein; KEGG: mex:Mext_0415 heavy metal transport/detoxification protein; Heavy metal transport/detoxification protein 436635 7116456 Mchl_0448 Methylobacterium extorquens CM4 Heavy metal transport/detoxification protein YP_002419312.1 436414 R 440085 CDS YP_002419313.1 218528497 7116457 436922..438400 1 NC_011757.1 PFAM: EAL domain protein; KEGG: mex:Mext_0416 EAL domain-containing protein; diguanylate phosphodiesterase 438400 7116457 Mchl_0449 Methylobacterium extorquens CM4 diguanylate phosphodiesterase YP_002419313.1 436922 D 440085 CDS YP_002419314.1 218528498 7116458 complement(438435..438662) 1 NC_011757.1 KEGG: mex:Mext_0417 hypothetical protein; hypothetical protein 438662 7116458 Mchl_0450 Methylobacterium extorquens CM4 hypothetical protein YP_002419314.1 438435 R 440085 CDS YP_002419315.1 218528499 7116459 complement(438833..439369) 1 NC_011757.1 KEGG: mex:Mext_0418 chemotaxis protein; chemotaxis phosphatase, CheZ 439369 7116459 Mchl_0451 Methylobacterium extorquens CM4 chemotaxis phosphatase, CheZ YP_002419315.1 438833 R 440085 CDS YP_002419316.1 218528500 7116460 complement(439553..439936) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mpo:Mpop_0489 response regulator receiver protein; response regulator receiver protein 439936 7116460 Mchl_0452 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419316.1 439553 R 440085 CDS YP_002419317.1 218528501 7116461 440243..441256 1 NC_011757.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; riboflavin kinase; KEGG: mex:Mext_0420 riboflavin biosynthesis protein RibF; riboflavin biosynthesis protein RibF 441256 7116461 Mchl_0453 Methylobacterium extorquens CM4 riboflavin biosynthesis protein RibF YP_002419317.1 440243 D 440085 CDS YP_002419318.1 218528502 7116462 complement(441447..442451) 1 NC_011757.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_0421 glyoxylate reductase; glyoxylate reductase 442451 7116462 Mchl_0454 Methylobacterium extorquens CM4 glyoxylate reductase YP_002419318.1 441447 R 440085 CDS YP_002419319.1 218528503 7116463 442778..443371 1 NC_011757.1 PFAM: protein of unknown function DUF1058; KEGG: mex:Mext_0422 hypothetical protein; hypothetical protein 443371 7116463 Mchl_0455 Methylobacterium extorquens CM4 hypothetical protein YP_002419319.1 442778 D 440085 CDS YP_002419320.1 218528504 7116464 complement(443475..443975) 1 NC_011757.1 PFAM: ferric-uptake regulator; KEGG: mex:Mext_0423 ferric-uptake regulator; Fur family ferric uptake regulator 443975 7116464 Mchl_0456 Methylobacterium extorquens CM4 Fur family ferric uptake regulator YP_002419320.1 443475 R 440085 CDS YP_002419321.1 218528505 7116465 444252..444791 1 NC_011757.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 444791 7116465 Mchl_0457 Methylobacterium extorquens CM4 3-hydroxydecanoyl-(acyl carrier protein) dehydratase YP_002419321.1 444252 D 440085 CDS YP_002419322.1 218528506 7114614 444951..446177 1 NC_011757.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 446177 7114614 Mchl_0458 Methylobacterium extorquens CM4 3-oxoacyl-(acyl carrier protein) synthase I YP_002419322.1 444951 D 440085 CDS YP_002419323.1 218528507 7114615 446331..446450 1 NC_011757.1 KEGG: mpo:Mpop_0496 hypothetical protein; hypothetical protein 446450 7114615 Mchl_0459 Methylobacterium extorquens CM4 hypothetical protein YP_002419323.1 446331 D 440085 CDS YP_002419324.1 218528508 7114616 446651..447481 1 NC_011757.1 KEGG: mex:Mext_0426 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 447481 7114616 Mchl_0460 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419324.1 446651 D 440085 CDS YP_002419325.1 218528509 7114617 447549..448310 1 NC_011757.1 KEGG: mex:Mext_0427 flagellar biosynthetic protein FliP; TIGRFAM: flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; flagellar biosynthetic protein FliP 448310 7114617 Mchl_0461 Methylobacterium extorquens CM4 flagellar biosynthetic protein FliP YP_002419325.1 447549 D 440085 CDS YP_002419326.1 218528510 7114618 448367..448768 1 NC_011757.1 PFAM: DoxX family protein; KEGG: mex:Mext_0428 DoxX family protein; DoxX family protein 448768 7114618 Mchl_0462 Methylobacterium extorquens CM4 DoxX family protein YP_002419326.1 448367 D 440085 CDS YP_002419327.1 218528511 7114619 complement(448772..452098) 1 NC_011757.1 KEGG: mex:Mext_0429 tetratricopeptide TPR_4 protein; tetratricopeptide TPR_4 protein 452098 7114619 Mchl_0463 Methylobacterium extorquens CM4 tetratricopeptide TPR_4 protein YP_002419327.1 448772 R 440085 CDS YP_002419328.1 218528512 7114620 complement(452238..452669) 1 NC_011757.1 KEGG: mex:Mext_0430 hypothetical protein; hypothetical protein 452669 7114620 Mchl_0464 Methylobacterium extorquens CM4 hypothetical protein YP_002419328.1 452238 R 440085 CDS YP_002419329.1 218528513 7114621 complement(452823..454970) 1 NC_011757.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: mex:Mext_0431 oligopeptidase B; oligopeptidase B 454970 7114621 Mchl_0465 Methylobacterium extorquens CM4 oligopeptidase B YP_002419329.1 452823 R 440085 CDS YP_002419330.1 218528514 7114622 455399..455836 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_0432 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 455836 7114622 Mchl_0466 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002419330.1 455399 D 440085 CDS YP_002419331.1 218528515 7114623 455982..456176 1 NC_011757.1 KEGG: mex:Mext_0433 hypothetical protein; hypothetical protein 456176 7114623 Mchl_0467 Methylobacterium extorquens CM4 hypothetical protein YP_002419331.1 455982 D 440085 CDS YP_002419332.1 218528516 7114624 456295..457137 1 NC_011757.1 KEGG: mex:Mext_0434 hypothetical protein; hypothetical protein 457137 7114624 Mchl_0468 Methylobacterium extorquens CM4 hypothetical protein YP_002419332.1 456295 D 440085 CDS YP_002419333.1 218528517 7114625 complement(457175..457603) 1 NC_011757.1 PFAM: Fe-S metabolism associated SufE; KEGG: mex:Mext_0435 Fe-S metabolism associated SufE; Fe-S metabolism associated SufE 457603 7114625 Mchl_0469 Methylobacterium extorquens CM4 Fe-S metabolism associated SufE YP_002419333.1 457175 R 440085 CDS YP_002419334.1 218528518 7114626 complement(457692..458771) 1 NC_011757.1 KEGG: mex:Mext_0436 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; hypothetical protein; SMART: PAC repeat-containing protein; signal transduction histidine kinase 458771 7114626 Mchl_0470 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002419334.1 457692 R 440085 CDS YP_002419335.1 218528519 7114627 complement(458924..462601) 1 NC_011757.1 KEGG: mex:Mext_0437 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; multi-sensor hybrid histidine kinase 462601 7114627 Mchl_0471 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002419335.1 458924 R 440085 CDS YP_002419336.1 218528520 7114628 463279..463788 1 NC_011757.1 KEGG: mex:Mext_0438 hypothetical protein; hypothetical protein 463788 7114628 Mchl_0472 Methylobacterium extorquens CM4 hypothetical protein YP_002419336.1 463279 D 440085 CDS YP_002419337.1 218528521 7114629 463904..464068 1 NC_011757.1 KEGG: mex:Mext_0439 hypothetical protein; hypothetical protein 464068 7114629 Mchl_0473 Methylobacterium extorquens CM4 hypothetical protein YP_002419337.1 463904 D 440085 CDS YP_002419338.1 218528522 7114630 complement(464115..464555) 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_0440 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 464555 7114630 Mchl_0474 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002419338.1 464115 R 440085 CDS YP_002419339.1 218528523 7114631 464978..465886 1 NC_011757.1 KEGG: mex:Mext_0541 hypothetical protein; hypothetical protein 465886 7114631 Mchl_0475 Methylobacterium extorquens CM4 hypothetical protein YP_002419339.1 464978 D 440085 CDS YP_002419340.1 218528524 7114632 465965..468601 1 NC_011757.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: mex:Mext_0542 aminopeptidase N; aminopeptidase N 468601 pepN 7114632 pepN Methylobacterium extorquens CM4 aminopeptidase N YP_002419340.1 465965 D 440085 CDS YP_002419341.1 218528525 7114633 468787..471147 1 NC_011757.1 KEGG: mex:Mext_0543 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor signal transduction histidine kinase 471147 7114633 Mchl_0477 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002419341.1 468787 D 440085 CDS YP_002419342.1 218528526 7114635 471554..472480 1 NC_011757.1 TIGRFAM: arginase; PFAM: arginase/agmatinase/formiminoglutamase; KEGG: mex:Mext_0544 arginase; arginase 472480 7114635 Mchl_0479 Methylobacterium extorquens CM4 arginase YP_002419342.1 471554 D 440085 CDS YP_002419343.1 218528527 7114636 complement(472516..473994) 1 NC_011757.1 KEGG: mex:Mext_0545 glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; glucose-6-phosphate 1-dehydrogenase 473994 7114636 Mchl_0480 Methylobacterium extorquens CM4 glucose-6-phosphate 1-dehydrogenase YP_002419343.1 472516 R 440085 CDS YP_002419344.1 218528528 7114637 complement(474265..474717) 1 NC_011757.1 KEGG: mex:Mext_0546 hypothetical protein; hypothetical protein 474717 7114637 Mchl_0481 Methylobacterium extorquens CM4 hypothetical protein YP_002419344.1 474265 R 440085 CDS YP_002419345.1 218528529 7114638 475093..475254 1 NC_011757.1 KEGG: mex:Mext_0547 hypothetical protein; hypothetical protein 475254 7114638 Mchl_0482 Methylobacterium extorquens CM4 hypothetical protein YP_002419345.1 475093 D 440085 CDS YP_002419346.1 218528530 7114639 complement(475334..475657) 1 NC_011757.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: mex:Mext_0548 CutA1 divalent ion tolerance protein; CutA1 divalent ion tolerance protein 475657 7114639 Mchl_0483 Methylobacterium extorquens CM4 CutA1 divalent ion tolerance protein YP_002419346.1 475334 R 440085 CDS YP_002419347.1 218528531 7114640 475763..476533 1 NC_011757.1 PFAM: ATP-NAD/AcoX kinase; KEGG: mex:Mext_0549 NAD(+) kinase; NAD(+) kinase 476533 7114640 Mchl_0484 Methylobacterium extorquens CM4 NAD(+) kinase YP_002419347.1 475763 D 440085 CDS YP_002419348.1 218528532 7114641 complement(476602..476814) 1 NC_011757.1 PFAM: protein of unknown function DUF1674; KEGG: mex:Mext_0550 hypothetical protein; hypothetical protein 476814 7114641 Mchl_0485 Methylobacterium extorquens CM4 hypothetical protein YP_002419348.1 476602 R 440085 CDS YP_002419349.1 218528533 7114642 476919..478283 1 NC_011757.1 PFAM: Fmu (Sun) domain protein; methyltransferase small; methyltransferase type 11; KEGG: mex:Mext_0551 Fmu (Sun) domain-containing protein; Fmu (Sun) domain-containing protein 478283 7114642 Mchl_0486 Methylobacterium extorquens CM4 Fmu (Sun) domain-containing protein YP_002419349.1 476919 D 440085 CDS YP_002419350.1 218528534 7114643 complement(478345..478509) 1 NC_011757.1 KEGG: mex:Mext_0552 hypothetical protein; hypothetical protein 478509 7114643 Mchl_0487 Methylobacterium extorquens CM4 hypothetical protein YP_002419350.1 478345 R 440085 CDS YP_002419351.1 218528535 7114644 478817..479890 1 NC_011757.1 KEGG: mex:Mext_0553 hypothetical protein; hypothetical protein 479890 7114644 Mchl_0488 Methylobacterium extorquens CM4 hypothetical protein YP_002419351.1 478817 D 440085 CDS YP_002419352.1 218528536 7114645 480260..481453 1 NC_011757.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: mex:Mext_0554 aminotransferase class I and II; class I and II aminotransferase 481453 7114645 Mchl_0489 Methylobacterium extorquens CM4 class I and II aminotransferase YP_002419352.1 480260 D 440085 CDS YP_002419353.1 218528537 7114646 complement(481514..481843) 1 NC_011757.1 KEGG: mex:Mext_0555 hypothetical protein; hypothetical protein 481843 7114646 Mchl_0490 Methylobacterium extorquens CM4 hypothetical protein YP_002419353.1 481514 R 440085 CDS YP_002419354.1 218528538 7114647 482189..483121 1 NC_011757.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: mex:Mext_0556 malonyl CoA-acyl carrier protein transacylase; malonyl CoA-acyl carrier protein transacylase 483121 7114647 Mchl_0491 Methylobacterium extorquens CM4 malonyl CoA-acyl carrier protein transacylase YP_002419354.1 482189 D 440085 CDS YP_002419355.1 218528539 7114648 483231..483971 1 NC_011757.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; KEGG: mex:Mext_0557 3-oxoacyl-(acyl-carrier-protein) reductase; 3-oxoacyl-(acyl-carrier-protein) reductase 483971 7114648 Mchl_0492 Methylobacterium extorquens CM4 3-oxoacyl-(acyl-carrier-protein) reductase YP_002419355.1 483231 D 440085 CDS YP_002419356.1 218528540 7114649 484235..484471 1 NC_011757.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 484471 acpP 7114649 acpP Methylobacterium extorquens CM4 acyl carrier protein YP_002419356.1 484235 D 440085 CDS YP_002419357.1 218528541 7114650 484610..485872 1 NC_011757.1 TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: beta-ketoacyl synthase; KEGG: mex:Mext_0559 3-oxoacyl-(acyl-carrier-protein) synthase 2; 3-oxoacyl-(acyl-carrier-protein) synthase 2 485872 7114650 Mchl_0494 Methylobacterium extorquens CM4 3-oxoacyl-(acyl-carrier-protein) synthase 2 YP_002419357.1 484610 D 440085 CDS YP_002419358.1 218528542 7114651 486135..487538 1 NC_011757.1 PFAM: aminodeoxychorismate lyase; KEGG: mex:Mext_0560 aminodeoxychorismate lyase; aminodeoxychorismate lyase 487538 7114651 Mchl_0495 Methylobacterium extorquens CM4 aminodeoxychorismate lyase YP_002419358.1 486135 D 440085 CDS YP_002419359.1 218528543 7114652 complement(487569..488315) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: mex:Mext_0561 HAD family hydrolase; HAD-superfamily hydrolase 488315 7114652 Mchl_0496 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002419359.1 487569 R 440085 CDS YP_002419360.1 218528544 7114653 complement(488299..490686) 1 NC_011757.1 PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: mex:Mext_0562 kojibiose phosphorylase; Kojibiose phosphorylase 490686 7114653 Mchl_0497 Methylobacterium extorquens CM4 Kojibiose phosphorylase YP_002419360.1 488299 R 440085 CDS YP_002419361.1 218528545 7114654 491553..492755 1 NC_011757.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: mex:Mext_0563 acetate kinase; acetate kinase 492755 7114654 Mchl_0498 Methylobacterium extorquens CM4 acetate kinase YP_002419361.1 491553 D 440085 CDS YP_002419362.1 218528546 7114655 492752..493783 1 NC_011757.1 PFAM: secretion protein HlyD; KEGG: mex:Mext_0564 secretion protein HlyD; secretion protein HlyD 493783 7114655 Mchl_0499 Methylobacterium extorquens CM4 secretion protein HlyD YP_002419362.1 492752 D 440085 CDS YP_002419363.1 218528547 7114656 493791..496529 1 NC_011757.1 PFAM: ABC transporter; ABC-2 type transporter; SMART: ATPase AAA; KEGG: mex:Mext_0565 ABC transporter; ABC transporter 496529 7114656 Mchl_0500 Methylobacterium extorquens CM4 ABC transporter YP_002419363.1 493791 D 440085 CDS YP_002419364.1 218528548 7114657 496531..497730 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_0566 ABC-2 type transporter; ABC transporter 497730 7114657 Mchl_0501 Methylobacterium extorquens CM4 ABC transporter YP_002419364.1 496531 D 440085 CDS YP_002419365.1 218528549 7114658 497810..500245 1 NC_011757.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mex:Mext_0567 phosphoketolase; phosphoketolase 500245 7114658 Mchl_0502 Methylobacterium extorquens CM4 phosphoketolase YP_002419365.1 497810 D 440085 CDS YP_002419366.1 218528550 7114659 500369..501499 1 NC_011757.1 PFAM: monooxygenase FAD-binding; KEGG: mex:Mext_0568 monooxygenase FAD-binding; FAD-binding monooxygenase 501499 7114659 Mchl_0503 Methylobacterium extorquens CM4 FAD-binding monooxygenase YP_002419366.1 500369 D 440085 CDS YP_002419367.1 218528551 7114660 501777..503384 1 NC_011757.1 KEGG: mrd:Mrad2831_5192 hypothetical protein; hypothetical protein 503384 7114660 Mchl_0504 Methylobacterium extorquens CM4 hypothetical protein YP_002419367.1 501777 D 440085 CDS YP_002419368.1 218528552 7114661 complement(503381..503581) 1 NC_011757.1 KEGG: mrd:Mrad2831_4144 hypothetical protein; hypothetical protein 503581 7114661 Mchl_0505 Methylobacterium extorquens CM4 hypothetical protein YP_002419368.1 503381 R 440085 CDS YP_002419369.1 218528553 7114662 503991..504407 1 NC_011757.1 hypothetical protein 504407 7114662 Mchl_0506 Methylobacterium extorquens CM4 hypothetical protein YP_002419369.1 503991 D 440085 CDS YP_002419370.1 218528554 7114663 504581..505591 1 NC_011757.1 KEGG: mpo:Mpop_0167 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 505591 7114663 Mchl_0507 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002419370.1 504581 D 440085 CDS YP_002419371.1 218528555 7114664 complement(505666..507564) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_5233 histidine kinase; histidine kinase 507564 7114664 Mchl_0508 Methylobacterium extorquens CM4 histidine kinase YP_002419371.1 505666 R 440085 CDS YP_002419372.1 218528556 7114665 complement(507561..508562) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: mrd:Mrad2831_5232 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 508562 7114665 Mchl_0509 Methylobacterium extorquens CM4 anti-sigma regulatory factor, serine/threonine protein kinase YP_002419372.1 507561 R 440085 CDS YP_002419373.1 218528557 7114666 complement(508565..508969) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mrd:Mrad2831_5231 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 508969 7114666 Mchl_0510 Methylobacterium extorquens CM4 anti-sigma regulatory factor, serine/threonine protein kinase YP_002419373.1 508565 R 440085 CDS YP_002419374.1 218528558 7114667 complement(508950..509351) 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; KEGG: mrd:Mrad2831_5230 anti-sigma-factor antagonist; anti-sigma-factor antagonist 509351 7114667 Mchl_0511 Methylobacterium extorquens CM4 anti-sigma-factor antagonist YP_002419374.1 508950 R 440085 CDS YP_002419375.1 218528559 7114668 complement(509356..510234) 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; KEGG: mrd:Mrad2831_5229 anti-sigma-factor antagonist; anti-sigma-factor antagonist 510234 7114668 Mchl_0512 Methylobacterium extorquens CM4 anti-sigma-factor antagonist YP_002419375.1 509356 R 440085 CDS YP_002419376.1 218528560 7114670 510659..510922 1 NC_011757.1 KEGG: mrd:Mrad2831_5546 hypothetical protein; hypothetical protein 510922 7114670 Mchl_0514 Methylobacterium extorquens CM4 hypothetical protein YP_002419376.1 510659 D 440085 CDS YP_002419377.1 218528561 7114671 complement(510941..512191) 1 NC_011757.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: mpo:Mpop_3728 signal transduction histidine kinase; signal transduction histidine kinase 512191 7114671 Mchl_0515 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002419377.1 510941 R 440085 CDS YP_002419378.1 218528562 7114672 512580..512954 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mpo:Mpop_0095 response regulator receiver protein; response regulator receiver protein 512954 7114672 Mchl_0516 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419378.1 512580 D 440085 CDS YP_002419379.1 218528563 7114673 complement(513038..515218) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: mpo:Mpop_0171 multi-sensor hybrid histidine kinase; histidine kinase 515218 7114673 Mchl_0517 Methylobacterium extorquens CM4 histidine kinase YP_002419379.1 513038 R 440085 CDS YP_002419380.1 218528564 7114674 complement(515378..516898) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mpo:Mpop_0175 diguanylate cyclase; diguanylate cyclase 516898 7114674 Mchl_0518 Methylobacterium extorquens CM4 diguanylate cyclase YP_002419380.1 515378 R 440085 CDS YP_002419381.1 218528565 7114675 517132..517377 1 NC_011757.1 KEGG: mpo:Mpop_0176 hypothetical protein; hypothetical protein 517377 7114675 Mchl_0519 Methylobacterium extorquens CM4 hypothetical protein YP_002419381.1 517132 D 440085 CDS YP_002419382.1 218528566 7114676 complement(517559..517858) 1 NC_011757.1 KEGG: mex:Mext_1918 hypothetical protein; hypothetical protein 517858 7114676 Mchl_0520 Methylobacterium extorquens CM4 hypothetical protein YP_002419382.1 517559 R 440085 CDS YP_002419383.1 218528567 7114678 518933..519484 1 NC_011757.1 PFAM: inorganic pyrophosphatase; KEGG: bid:Bind_2987 inorganic pyrophosphatase; inorganic pyrophosphatase 519484 7114678 Mchl_0522 Methylobacterium extorquens CM4 inorganic pyrophosphatase YP_002419383.1 518933 D 440085 CDS YP_002419384.1 218528568 7114679 519860..520225 1 NC_011757.1 KEGG: met:M446_1189 hypothetical protein; hypothetical protein 520225 7114679 Mchl_0523 Methylobacterium extorquens CM4 hypothetical protein YP_002419384.1 519860 D 440085 CDS YP_002419385.1 218528569 7114681 521087..521842 1 NC_011757.1 PFAM: EAL domain protein; KEGG: mex:Mext_3242 EAL domain-containing protein; diguanylate phosphodiesterase 521842 7114681 Mchl_0525 Methylobacterium extorquens CM4 diguanylate phosphodiesterase YP_002419385.1 521087 D 440085 CDS YP_002419386.1 218528570 7114682 complement(521953..522426) 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; KEGG: mex:Mext_0113 PAS sensor protein; PAS/PAC sensor protein 522426 7114682 Mchl_0526 Methylobacterium extorquens CM4 PAS/PAC sensor protein YP_002419386.1 521953 R 440085 CDS YP_002419387.1 218528571 7114683 522650..523102 1 NC_011757.1 PFAM: BLUF domain protein; KEGG: mex:Mext_0114 BLUF domain-containing protein; BLUF domain-containing protein 523102 7114683 Mchl_0527 Methylobacterium extorquens CM4 BLUF domain-containing protein YP_002419387.1 522650 D 440085 CDS YP_002419388.1 218528572 7114684 523107..523580 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mpo:Mpop_3155 response regulator receiver protein; response regulator receiver protein 523580 7114684 Mchl_0528 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419388.1 523107 D 440085 CDS YP_002419389.1 218528573 7114685 complement(523690..523821) 1 NC_011757.1 KEGG: mex:Mext_1129 hypothetical protein; hypothetical protein 523821 7114685 Mchl_0529 Methylobacterium extorquens CM4 hypothetical protein YP_002419389.1 523690 R 440085 CDS YP_002419390.1 218528574 7114686 523898..526285 1 NC_011757.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein; PAS fold-4 domain protein; KEGG: mpo:Mpop_0141 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase 526285 7114686 Mchl_0530 Methylobacterium extorquens CM4 PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase YP_002419390.1 523898 D 440085 CDS YP_002419391.1 218528575 7114687 526936..528108 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: met:M446_0110 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 528108 7114687 Mchl_0531 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES domain-containing protein YP_002419391.1 526936 D 440085 CDS YP_002419392.1 218528576 7114688 528180..528785 1 NC_011757.1 KEGG: met:M446_0111 hypothetical protein; hypothetical protein 528785 7114688 Mchl_0532 Methylobacterium extorquens CM4 hypothetical protein YP_002419392.1 528180 D 440085 CDS YP_002419393.1 218528577 7114689 528808..529932 1 NC_011757.1 KEGG: met:M446_0112 hypothetical protein; hypothetical protein 529932 7114689 Mchl_0533 Methylobacterium extorquens CM4 hypothetical protein YP_002419393.1 528808 D 440085 CDS YP_002419394.1 218528578 7114690 complement(530059..530844) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mfa:Mfla_0397 AraC family transcriptional regulator; AraC family transcriptional regulator 530844 7114690 Mchl_0534 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419394.1 530059 R 440085 CDS YP_002419395.1 218528579 7114691 531159..531626 1 NC_011757.1 KEGG: mpo:Mpop_4442 hypothetical protein; hypothetical protein 531626 7114691 Mchl_0535 Methylobacterium extorquens CM4 hypothetical protein YP_002419395.1 531159 D 440085 CDS YP_002419396.1 218528580 7114692 531619..532149 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mpo:Mpop_2952 MucR family transcriptional regulator; MucR family transcriptional regulator 532149 7114692 Mchl_0536 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002419396.1 531619 D 440085 CDS YP_002419397.1 218528581 7114853 complement(532426..533868) 1 NC_011757.1 KEGG: mpo:Mpop_3896 hypothetical protein; hypothetical protein 533868 7114853 Mchl_0537 Methylobacterium extorquens CM4 hypothetical protein YP_002419397.1 532426 R 440085 CDS YP_002419398.1 218528582 7114854 complement(534478..535569) 1 NC_011757.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_3509 metal-dependent phosphohydrolase; response regulator receiver modulated metal dependent phosphohydrolase 535569 7114854 Mchl_0538 Methylobacterium extorquens CM4 response regulator receiver modulated metal dependent phosphohydrolase YP_002419398.1 534478 R 440085 CDS YP_002419399.1 218528583 7117781 complement(536453..539722) 1 NC_011757.1 KEGG: mpo:Mpop_0149 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; multi-sensor hybrid histidine kinase 539722 7117781 Mchl_0540 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002419399.1 536453 R 440085 CDS YP_002419400.1 218528584 7117782 complement(540461..541036) 1 NC_011757.1 PFAM: TadE family protein; KEGG: mrd:Mrad2831_2082 TadE family protein; TadE family protein 541036 7117782 Mchl_0541 Methylobacterium extorquens CM4 TadE family protein YP_002419400.1 540461 R 440085 CDS YP_002419401.1 218528585 7117783 complement(541033..541614) 1 NC_011757.1 PFAM: TadE family protein; KEGG: mrd:Mrad2831_2083 TadE family protein; TadE family protein 541614 7117783 Mchl_0542 Methylobacterium extorquens CM4 TadE family protein YP_002419401.1 541033 R 440085 CDS YP_002419402.1 218528586 7117784 complement(541611..543167) 1 NC_011757.1 KEGG: pzu:PHZ_c1612 hypothetical protein; hypothetical protein 543167 7117784 Mchl_0543 Methylobacterium extorquens CM4 hypothetical protein YP_002419402.1 541611 R 440085 CDS YP_002419403.1 218528587 7117785 544671..545318 1 NC_011757.1 PFAM: protein of unknown function DUF159; KEGG: mex:Mext_3586 hypothetical protein; hypothetical protein 545318 7117785 Mchl_0544 Methylobacterium extorquens CM4 hypothetical protein YP_002419403.1 544671 D 440085 CDS YP_002419404.1 218528588 7117786 complement(545412..545603) 1 NC_011757.1 hypothetical protein 545603 7117786 Mchl_0545 Methylobacterium extorquens CM4 hypothetical protein YP_002419404.1 545412 R 440085 CDS YP_002419405.1 218528589 7117787 complement(545909..546226) 1 NC_011757.1 KEGG: mex:Mext_1866 hypothetical protein; hypothetical protein 546226 7117787 Mchl_0546 Methylobacterium extorquens CM4 hypothetical protein YP_002419405.1 545909 R 440085 CDS YP_002419406.1 218528590 7117789 complement(546707..546952) 1 NC_011757.1 hypothetical protein 546952 7117789 Mchl_0548 Methylobacterium extorquens CM4 hypothetical protein YP_002419406.1 546707 R 440085 CDS YP_002419407.1 218528591 7117792 548476..549072 1 NC_011757.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: mpo:Mpop_2198 transcriptional regulator, XRE family; XRE family transcriptional regulator 549072 7117792 Mchl_0551 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419407.1 548476 D 440085 CDS YP_002419408.1 218528592 7117795 complement(550690..551229) 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: gka:GK2787 thiol peroxidase (superoxide-inducible protein 8); redoxin 551229 7117795 Mchl_0554 Methylobacterium extorquens CM4 redoxin YP_002419408.1 550690 R 440085 CDS YP_002419409.1 218528593 7117796 complement(552207..553430) 1 NC_011757.1 KEGG: mex:Mext_2100 hypothetical protein; hypothetical protein 553430 7117796 Mchl_0555 Methylobacterium extorquens CM4 hypothetical protein YP_002419409.1 552207 R 440085 CDS YP_002419410.1 218528594 7117797 complement(553957..554820) 1 NC_011757.1 TIGRFAM: ferredoxin-type protein, NapH/MauN family; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pde:Pden_4738 ferredoxin-type protein, NapH/MauN family; ferredoxin-type protein, NapH/MauN family 554820 7117797 Mchl_0556 Methylobacterium extorquens CM4 ferredoxin-type protein, NapH/MauN family YP_002419410.1 553957 R 440085 CDS YP_002419411.1 218528595 7117798 complement(554820..555482) 1 NC_011757.1 TIGRFAM: MauM/NapG family ferredoxin-type protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pde:Pden_4737 MauM/NapG family ferredoxin-type protein; MauM/NapG family ferredoxin-type protein 555482 7117798 Mchl_0557 Methylobacterium extorquens CM4 MauM/NapG family ferredoxin-type protein YP_002419411.1 554820 R 440085 CDS YP_002419412.1 218528596 7117799 complement(555501..555845) 1 NC_011757.1 KEGG: mfa:Mfla_0553 hypothetical protein; hypothetical protein 555845 7117799 Mchl_0558 Methylobacterium extorquens CM4 hypothetical protein YP_002419412.1 555501 R 440085 CDS YP_002419413.1 218528597 7117800 complement(555859..556920) 1 NC_011757.1 PFAM: Di-haem cytochrome C peroxidase; KEGG: mfa:Mfla_0552 cytochrome-c peroxidase; cytochrome-c peroxidase 556920 7117800 Mchl_0559 Methylobacterium extorquens CM4 cytochrome-c peroxidase YP_002419413.1 555859 R 440085 CDS YP_002419414.1 218528598 7117801 complement(556954..557841) 1 NC_011757.1 KEGG: pde:Pden_4735 hypothetical protein; hypothetical protein 557841 7117801 Mchl_0560 Methylobacterium extorquens CM4 hypothetical protein YP_002419414.1 556954 R 440085 CDS YP_002419415.1 218528599 7117802 complement(557976..558335) 1 NC_011757.1 TIGRFAM: amicyanin; PFAM: blue (type 1) copper domain protein; KEGG: pde:Pden_4734 amicyanin; amicyanin 558335 7117802 Mchl_0561 Methylobacterium extorquens CM4 amicyanin YP_002419415.1 557976 R 440085 CDS YP_002419416.1 218528600 7117803 complement(558408..558968) 1 NC_011757.1 KEGG: pde:Pden_4733 methylamine dehydrogenase light chain; TIGRFAM: methylamine dehydrogenase light chain; PFAM: methylamine dehydrogenase light chain domain protein; methylamine dehydrogenase light chain 558968 7117803 Mchl_0562 Methylobacterium extorquens CM4 methylamine dehydrogenase light chain YP_002419416.1 558408 R 440085 CDS YP_002419417.1 218528601 7117804 complement(559026..559643) 1 NC_011757.1 TIGRFAM: methylamine dehydrogenase accessory protein MauD; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: pde:Pden_4732 methylamine dehydrogenase accessory protein MauD; methylamine dehydrogenase accessory protein MauD 559643 7117804 Mchl_0563 Methylobacterium extorquens CM4 methylamine dehydrogenase accessory protein MauD YP_002419417.1 559026 R 440085 CDS YP_002419418.1 218528602 7117805 complement(559649..560209) 1 NC_011757.1 PFAM: methylamine utilisation MauE; KEGG: pde:Pden_4731 methylamine utilisation MauE; methylamine utilisation MauE 560209 7117805 Mchl_0564 Methylobacterium extorquens CM4 methylamine utilisation MauE YP_002419418.1 559649 R 440085 CDS YP_002419419.1 218528603 7117806 complement(560209..561441) 1 NC_011757.1 KEGG: pde:Pden_4730 methylamine dehydrogenase heavy chain; TIGRFAM: methylamine dehydrogenase heavy chain; PFAM: methylamine dehydrogenase heavy subunit; methylamine dehydrogenase heavy chain 561441 7117806 Mchl_0565 Methylobacterium extorquens CM4 methylamine dehydrogenase heavy chain YP_002419419.1 560209 R 440085 CDS YP_002419420.1 218528604 7117807 complement(561508..562365) 1 NC_011757.1 KEGG: pde:Pden_4729 hypothetical protein; hypothetical protein 562365 7117807 Mchl_0566 Methylobacterium extorquens CM4 hypothetical protein YP_002419420.1 561508 R 440085 CDS YP_002419421.1 218528605 7117812 complement(563552..565888) 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mrd:Mrad2831_5661 TonB-dependent receptor; TonB-dependent receptor 565888 7117812 Mchl_0571 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002419421.1 563552 R 440085 CDS YP_002419422.1 218528606 7117813 complement(565993..567369) 1 NC_011757.1 PFAM: PepSY-associated TM helix domain protein; KEGG: mrd:Mrad2831_5663 PepSY-associated TM helix domain-containing protein; PepSY-associated TM helix domain-containing protein 567369 7117813 Mchl_0572 Methylobacterium extorquens CM4 PepSY-associated TM helix domain-containing protein YP_002419422.1 565993 R 440085 CDS YP_002419423.1 218528607 7117814 complement(567410..567778) 1 NC_011757.1 KEGG: mpo:Mpop_3046 hypothetical protein; hypothetical protein 567778 7117814 Mchl_0573 Methylobacterium extorquens CM4 hypothetical protein YP_002419423.1 567410 R 440085 CDS YP_002419424.1 218528608 7117815 complement(567932..568186) 1 NC_011757.1 hypothetical protein 568186 7117815 Mchl_0574 Methylobacterium extorquens CM4 hypothetical protein YP_002419424.1 567932 R 440085 CDS YP_002419425.1 218528609 7117816 568574..568705 1 NC_011757.1 KEGG: rec:RHECIAT_PA0000344 hypothetical protein; hypothetical protein 568705 7117816 Mchl_0575 Methylobacterium extorquens CM4 hypothetical protein YP_002419425.1 568574 D 440085 CDS YP_002419426.1 218528610 7117817 568751..569680 1 NC_011757.1 KEGG: rec:RHECIAT_PA0000344 hypothetical protein; hypothetical protein 569680 7117817 Mchl_0576 Methylobacterium extorquens CM4 hypothetical protein YP_002419426.1 568751 D 440085 CDS YP_002419427.1 218528611 7117818 569677..570021 1 NC_011757.1 KEGG: mrd:Mrad2831_5316 hypothetical protein; hypothetical protein 570021 7117818 Mchl_0577 Methylobacterium extorquens CM4 hypothetical protein YP_002419427.1 569677 D 440085 CDS YP_002419428.1 218528612 7117820 570810..571868 1 NC_011757.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: mex:Mext_0569 ABC transporter; ABC transporter 571868 7117820 Mchl_0578 Methylobacterium extorquens CM4 ABC transporter YP_002419428.1 570810 D 440085 CDS YP_002419429.1 218528613 7117821 571971..572996 1 NC_011757.1 PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_0570 extracellular solute-binding protein; family 1 extracellular solute-binding protein 572996 7117821 Mchl_0579 Methylobacterium extorquens CM4 family 1 extracellular solute-binding protein YP_002419429.1 571971 D 440085 CDS YP_002419430.1 218528614 7117822 573073..574725 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0571 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 574725 7117822 Mchl_0580 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002419430.1 573073 D 440085 CDS YP_002419431.1 218528615 7117823 complement(574733..574834) 1 NC_011757.1 KEGG: mpo:Mpop_0545 hypothetical protein; hypothetical protein 574834 7117823 Mchl_0581 Methylobacterium extorquens CM4 hypothetical protein YP_002419431.1 574733 R 440085 CDS YP_002419432.1 218528616 7117824 complement(575148..575402) 1 NC_011757.1 KEGG: mex:Mext_0572 hypothetical protein; hypothetical protein 575402 7117824 Mchl_0582 Methylobacterium extorquens CM4 hypothetical protein YP_002419432.1 575148 R 440085 CDS YP_002419433.1 218528617 7117825 complement(575673..576398) 1 NC_011757.1 PFAM: protein of unknown function DUF540; KEGG: mex:Mext_0573 hypothetical protein; hypothetical protein 576398 7117825 Mchl_0583 Methylobacterium extorquens CM4 hypothetical protein YP_002419433.1 575673 R 440085 CDS YP_002419434.1 218528618 7117826 576558..577523 1 NC_011757.1 PFAM: hypothetical protein; Kelch repeat protein; KEGG: mex:Mext_0574 kelch repeat-containing protein; hypothetical protein 577523 7117826 Mchl_0584 Methylobacterium extorquens CM4 hypothetical protein YP_002419434.1 576558 D 440085 CDS YP_002419435.1 218528619 7117827 577611..578939 1 NC_011757.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_0575 amine oxidase; amine oxidase 578939 7117827 Mchl_0585 Methylobacterium extorquens CM4 amine oxidase YP_002419435.1 577611 D 440085 CDS YP_002419436.1 218528620 7117828 579048..579683 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_0576 cyclic nucleotide-binding; cyclic nucleotide-binding protein 579683 7117828 Mchl_0586 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002419436.1 579048 D 440085 CDS YP_002419437.1 218528621 7117829 complement(579687..580106) 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_0577 cupin 2 domain-containing protein; cupin 580106 7117829 Mchl_0587 Methylobacterium extorquens CM4 cupin YP_002419437.1 579687 R 440085 CDS YP_002419438.1 218528622 7117830 580314..580517 1 NC_011757.1 KEGG: mpo:Mpop_0552 hypothetical protein; hypothetical protein 580517 7117830 Mchl_0588 Methylobacterium extorquens CM4 hypothetical protein YP_002419438.1 580314 D 440085 CDS YP_002419439.1 218528623 7117831 complement(580677..580790) 1 NC_011757.1 KEGG: mpo:Mpop_0553 hypothetical protein; hypothetical protein 580790 7117831 Mchl_0589 Methylobacterium extorquens CM4 hypothetical protein YP_002419439.1 580677 R 440085 CDS YP_002419440.1 218528624 7117832 complement(580944..581234) 1 NC_011757.1 KEGG: mex:Mext_0579 hypothetical protein; hypothetical protein 581234 7117832 Mchl_0590 Methylobacterium extorquens CM4 hypothetical protein YP_002419440.1 580944 R 440085 CDS YP_002419441.1 218528625 7117833 581512..581658 1 NC_011757.1 KEGG: mpo:Mpop_0555 hypothetical protein; hypothetical protein 581658 7117833 Mchl_0591 Methylobacterium extorquens CM4 hypothetical protein YP_002419441.1 581512 D 440085 CDS YP_002419442.1 218528626 7117834 581869..582936 1 NC_011757.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_0581 sulfate ABC transporter periplasmic sulfate-binding protein; sulfate ABC transporter periplasmic sulfate-binding protein 582936 7117834 Mchl_0592 Methylobacterium extorquens CM4 sulfate ABC transporter periplasmic sulfate-binding protein YP_002419442.1 581869 D 440085 CDS YP_002419443.1 218528627 7117835 582941..583795 1 NC_011757.1 TIGRFAM: sulfate ABC transporter inner membrane subunit; sulfate ABC transporter inner membrane subunit CysT; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0582 sulfate ABC transporter inner membrane subunit CysT; sulfate ABC transporter inner membrane subunit CysT 583795 7117835 Mchl_0593 Methylobacterium extorquens CM4 sulfate ABC transporter inner membrane subunit CysT YP_002419443.1 582941 D 440085 CDS YP_002419444.1 218528628 7117836 583788..584690 1 NC_011757.1 TIGRFAM: sulfate ABC transporter inner membrane subunit; sulfate ABC transporter inner membrane subunit CysW; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_0583 sulfate ABC transporter inner membrane subunit CysW; sulfate ABC transporter inner membrane subunit CysW 584690 7117836 Mchl_0594 Methylobacterium extorquens CM4 sulfate ABC transporter inner membrane subunit CysW YP_002419444.1 583788 D 440085 CDS YP_002419445.1 218528629 7117837 584695..585738 1 NC_011757.1 KEGG: mex:Mext_0584 sulfate ABC transporter ATPase subunit; TIGRFAM: sulfate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; sulfate ABC transporter ATPase 585738 7117837 Mchl_0595 Methylobacterium extorquens CM4 sulfate ABC transporter ATPase YP_002419445.1 584695 D 440085 CDS YP_002419446.1 218528630 7117844 complement(592203..592724) 1 NC_011757.1 KEGG: mex:Mext_0585 hypothetical protein; hypothetical protein 592724 7117844 Mchl_0596 Methylobacterium extorquens CM4 hypothetical protein YP_002419446.1 592203 R 440085 CDS YP_002419447.1 218528631 7117845 592856..593557 1 NC_011757.1 KEGG: mex:Mext_0586 endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD family protein; endonuclease III/Nth; endonuclease III 593557 7117845 Mchl_0597 Methylobacterium extorquens CM4 endonuclease III YP_002419447.1 592856 D 440085 CDS YP_002419448.1 218528632 7117846 593751..594545 1 NC_011757.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 594545 7117846 Mchl_0598 Methylobacterium extorquens CM4 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002419448.1 593751 D 440085 CDS YP_002419449.1 218528633 7117847 complement(594552..596207) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_0588 glycosyl transferase; family 2 glycosyl transferase 596207 7117847 Mchl_0599 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419449.1 594552 R 440085 CDS YP_002419450.1 218528634 7117848 complement(596204..598258) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_0589 glycosyl transferase; family 2 glycosyl transferase 598258 7117848 Mchl_0600 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419450.1 596204 R 440085 CDS YP_002419451.1 218528635 7117849 complement(598317..598949) 1 NC_011757.1 KEGG: mex:Mext_0590 hypothetical protein; hypothetical protein 598949 7117849 Mchl_0601 Methylobacterium extorquens CM4 hypothetical protein YP_002419451.1 598317 R 440085 CDS YP_002419452.1 218528636 7117850 complement(599010..599552) 1 NC_011757.1 PFAM: invasion associated locus B family protein; KEGG: mex:Mext_0591 invasion associated locus B family protein; invasion associated locus B family protein 599552 7117850 Mchl_0602 Methylobacterium extorquens CM4 invasion associated locus B family protein YP_002419452.1 599010 R 440085 CDS YP_002419453.1 218528637 7117851 599789..600208 1 NC_011757.1 KEGG: mex:Mext_0592 hypothetical protein; hypothetical protein 600208 7117851 Mchl_0603 Methylobacterium extorquens CM4 hypothetical protein YP_002419453.1 599789 D 440085 CDS YP_002419454.1 218528638 7117852 complement(600296..601021) 1 NC_011757.1 PFAM: protein of unknown function DUF45; KEGG: mex:Mext_0593 hypothetical protein; hypothetical protein 601021 7117852 Mchl_0604 Methylobacterium extorquens CM4 hypothetical protein YP_002419454.1 600296 R 440085 CDS YP_002419455.1 218528639 7117853 complement(601117..602361) 1 NC_011757.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: mex:Mext_0594 polyhydroxyalkanoate depolymerase, intracellular; polyhydroxyalkanoate depolymerase, intracellular 602361 7117853 Mchl_0605 Methylobacterium extorquens CM4 polyhydroxyalkanoate depolymerase, intracellular YP_002419455.1 601117 R 440085 CDS YP_002419456.1 218528640 7117854 602507..603901 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_0595 ATPase domain-containing protein; histidine kinase 603901 7117854 Mchl_0606 Methylobacterium extorquens CM4 histidine kinase YP_002419456.1 602507 D 440085 CDS YP_002419457.1 218528641 7117855 603938..604540 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_0596 response regulator receiver; response regulator receiver protein 604540 7117855 Mchl_0607 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419457.1 603938 D 440085 CDS YP_002419458.1 218528642 7117856 604722..604946 1 NC_011757.1 KEGG: mex:Mext_0597 hypothetical protein; hypothetical protein 604946 7117856 Mchl_0608 Methylobacterium extorquens CM4 hypothetical protein YP_002419458.1 604722 D 440085 CDS YP_002419459.1 218528643 7117857 605138..605377 1 NC_011757.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; KEGG: mex:Mext_0598 phosphoribosylformylglycinamidine synthase, PurS; phosphoribosylformylglycinamidine synthase PurS 605377 7117857 Mchl_0609 Methylobacterium extorquens CM4 phosphoribosylformylglycinamidine synthase PurS YP_002419459.1 605138 D 440085 CDS YP_002419460.1 218528644 7117858 605377..606057 1 NC_011757.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 606057 7117858 Mchl_0610 Methylobacterium extorquens CM4 phosphoribosylformylglycinamidine synthase I YP_002419460.1 605377 D 440085 CDS YP_002419461.1 218528645 7117859 complement(606182..606727) 1 NC_011757.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 606727 7117859 Mchl_0611 Methylobacterium extorquens CM4 adenine phosphoribosyltransferase YP_002419461.1 606182 R 440085 CDS YP_002419462.1 218528646 7117860 complement(606808..607602) 1 NC_011757.1 PFAM: inositol monophosphatase; KEGG: mex:Mext_0601 inositol-phosphate phosphatase; inositol-phosphate phosphatase 607602 7117860 Mchl_0612 Methylobacterium extorquens CM4 inositol-phosphate phosphatase YP_002419462.1 606808 R 440085 CDS YP_002419463.1 218528647 7117861 complement(607886..608503) 1 NC_011757.1 PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_0602 thiamine monophosphate synthase; thiamine monophosphate synthase 608503 7117861 Mchl_0613 Methylobacterium extorquens CM4 thiamine monophosphate synthase YP_002419463.1 607886 R 440085 CDS YP_002419464.1 218528648 7115430 complement(608510..609331) 1 NC_011757.1 PFAM: thiazole biosynthesis protein; KEGG: mex:Mext_0603 thiazole biosynthesis protein; thiazole biosynthesis protein 609331 7115430 Mchl_0614 Methylobacterium extorquens CM4 thiazole biosynthesis protein YP_002419464.1 608510 R 440085 CDS YP_002419465.1 218528649 7115431 complement(609334..609546) 1 NC_011757.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS; thiamine biosynthesis protein ThiS 609546 7115431 Mchl_0615 Methylobacterium extorquens CM4 thiamine biosynthesis protein ThiS YP_002419465.1 609334 R 440085 CDS YP_002419466.1 218528650 7115432 complement(609543..610778) 1 NC_011757.1 TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: mex:Mext_0605 glycine oxidase ThiO; glycine oxidase ThiO 610778 7115432 Mchl_0616 Methylobacterium extorquens CM4 glycine oxidase ThiO YP_002419466.1 609543 R 440085 CDS YP_002419467.1 218528651 7115433 complement(611103..612377) 1 NC_011757.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mex:Mext_0606 adenylyl cyclase class-3/4/guanylyl cyclase; adenylate/guanylate cyclase 612377 7115433 Mchl_0617 Methylobacterium extorquens CM4 adenylate/guanylate cyclase YP_002419467.1 611103 R 440085 CDS YP_002419468.1 218528652 7115434 612674..613042 1 NC_011757.1 KEGG: mex:Mext_0607 hypothetical protein; hypothetical protein 613042 7115434 Mchl_0618 Methylobacterium extorquens CM4 hypothetical protein YP_002419468.1 612674 D 440085 CDS YP_002419469.1 218528653 7115435 613334..614338 1 NC_011757.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_0608 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 614338 7115435 Mchl_0619 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419469.1 613334 D 440085 CDS YP_002419470.1 218528654 7115436 614347..615690 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0609 major facilitator transporter; major facilitator superfamily protein 615690 7115436 Mchl_0620 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419470.1 614347 D 440085 CDS YP_002419471.1 218528655 7115437 complement(615735..617735) 1 NC_011757.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 617735 7115437 Mchl_0621 Methylobacterium extorquens CM4 RNA polymerase sigma factor RpoD YP_002419471.1 615735 R 440085 CDS YP_002419472.1 218528656 7115438 complement(617937..619862) 1 NC_011757.1 synthesizes RNA primers at the replication forks; DNA primase 619862 dnaG 7115438 dnaG Methylobacterium extorquens CM4 DNA primase YP_002419472.1 617937 R 440085 CDS YP_002419473.1 218528657 7115439 619997..620983 1 NC_011757.1 PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: mex:Mext_0612 gluconolactonase; gluconolactonase 620983 7115439 Mchl_0623 Methylobacterium extorquens CM4 gluconolactonase YP_002419473.1 619997 D 440085 CDS YP_002419474.1 218528658 7115440 620980..622146 1 NC_011757.1 PFAM: major royal jelly protein; KEGG: mex:Mext_0613 hypothetical protein; hypothetical protein 622146 7115440 Mchl_0624 Methylobacterium extorquens CM4 hypothetical protein YP_002419474.1 620980 D 440085 CDS YP_002419475.1 218528659 7115441 complement(622335..622793) 1 NC_011757.1 KEGG: mex:Mext_0614 GatB/YqeY; GatB/YqeY 622793 7115441 Mchl_0625 Methylobacterium extorquens CM4 GatB/YqeY YP_002419475.1 622335 R 440085 CDS YP_002419476.1 218528660 7115442 622983..624233 1 NC_011757.1 TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; carbamoyl-phosphate synthase small chain; KEGG: mex:Mext_0615 carbamoyl-phosphate synthase, small subunit; carbamoyl-phosphate synthase, small subunit 624233 7115442 Mchl_0626 Methylobacterium extorquens CM4 carbamoyl-phosphate synthase, small subunit YP_002419476.1 622983 D 440085 CDS YP_002419477.1 218528661 7115443 624371..624745 1 NC_011757.1 KEGG: mex:Mext_0616 hypothetical protein; hypothetical protein 624745 7115443 Mchl_0627 Methylobacterium extorquens CM4 hypothetical protein YP_002419477.1 624371 D 440085 CDS YP_002419478.1 218528662 7115444 complement(624786..627461) 1 NC_011757.1 KEGG: mex:Mext_0617 hypothetical protein; hypothetical protein 627461 7115444 Mchl_0628 Methylobacterium extorquens CM4 hypothetical protein YP_002419478.1 624786 R 440085 CDS YP_002419479.1 218528663 7115445 627619..628008 1 NC_011757.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal body rod protein FlgB 628008 flgB 7115445 flgB Methylobacterium extorquens CM4 flagellar basal body rod protein FlgB YP_002419479.1 627619 D 440085 CDS YP_002419480.1 218528664 7115446 628005..628421 1 NC_011757.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgC 628421 flgC 7115446 flgC Methylobacterium extorquens CM4 flagellar basal body rod protein FlgC YP_002419480.1 628005 D 440085 CDS YP_002419481.1 218528665 7115447 628435..628788 1 NC_011757.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: mex:Mext_0620 flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex protein FliE 628788 7115447 Mchl_0631 Methylobacterium extorquens CM4 flagellar hook-basal body complex protein FliE YP_002419481.1 628435 D 440085 CDS YP_002419482.1 218528666 7115448 628881..629669 1 NC_011757.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgG 629669 flgG 7115448 flgG Methylobacterium extorquens CM4 flagellar basal body rod protein FlgG YP_002419482.1 628881 D 440085 CDS YP_002419483.1 218528667 7115449 629735..630229 1 NC_011757.1 TIGRFAM: flagella basal body P-ring formation protein FlgA; KEGG: mex:Mext_0622 FlgA, flagellar basal-body P-ring formation protein; flagella basal body P-ring formation protein FlgA 630229 7115449 Mchl_0633 Methylobacterium extorquens CM4 flagella basal body P-ring formation protein FlgA YP_002419483.1 629735 D 440085 CDS YP_002419484.1 218528668 7115450 630226..631353 1 NC_011757.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar basal body P-ring protein 631353 flgI 7115450 flgI Methylobacterium extorquens CM4 flagellar basal body P-ring protein YP_002419484.1 630226 D 440085 CDS YP_002419485.1 218528669 7115451 631353..631937 1 NC_011757.1 KEGG: mex:Mext_0624 hypothetical protein; hypothetical protein 631937 7115451 Mchl_0635 Methylobacterium extorquens CM4 hypothetical protein YP_002419485.1 631353 D 440085 CDS YP_002419486.1 218528670 7115452 631937..632644 1 NC_011757.1 PFAM: flagellar L-ring protein; KEGG: mex:Mext_0625 flagellar L-ring protein; flagellar L-ring protein 632644 7115452 Mchl_0636 Methylobacterium extorquens CM4 flagellar L-ring protein YP_002419486.1 631937 D 440085 CDS YP_002419487.1 218528671 7115453 632727..633209 1 NC_011757.1 PFAM: flagellar basal body-associated protein FliL; KEGG: mex:Mext_0626 flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 633209 7115453 Mchl_0637 Methylobacterium extorquens CM4 flagellar basal body-associated protein FliL YP_002419487.1 632727 D 440085 CDS YP_002419488.1 218528672 7115454 633206..633988 1 NC_011757.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagellum; flagellar biosynthesis protein FliP 633988 fliP 7115454 fliP Methylobacterium extorquens CM4 flagellar biosynthesis protein FliP YP_002419488.1 633206 D 440085 CDS YP_002419489.1 218528673 7115455 complement(634150..634380) 1 NC_011757.1 KEGG: mex:Mext_0628 hypothetical protein; hypothetical protein 634380 7115455 Mchl_0639 Methylobacterium extorquens CM4 hypothetical protein YP_002419489.1 634150 R 440085 CDS YP_002419490.1 218528674 7115456 634494..636173 1 NC_011757.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 636173 fliF 7115456 fliF Methylobacterium extorquens CM4 flagellar MS-ring protein YP_002419490.1 634494 D 440085 CDS YP_002419491.1 218528675 7115457 636173..636898 1 NC_011757.1 KEGG: mex:Mext_0630 hypothetical protein; hypothetical protein 636898 7115457 Mchl_0641 Methylobacterium extorquens CM4 hypothetical protein YP_002419491.1 636173 D 440085 CDS YP_002419492.1 218528676 7115458 636900..638288 1 NC_011757.1 PFAM: OmpA/MotB domain protein; KEGG: mex:Mext_0631 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 638288 7115458 Mchl_0642 Methylobacterium extorquens CM4 OmpA/MotB domain-containing protein YP_002419492.1 636900 D 440085 CDS YP_002419493.1 218528677 7115459 638285..639667 1 NC_011757.1 a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation; chemotaxis protein 639667 7115459 Mchl_0643 Methylobacterium extorquens CM4 chemotaxis protein YP_002419493.1 638285 D 440085 CDS YP_002419494.1 218528678 7115460 639707..641524 1 NC_011757.1 KEGG: mex:Mext_0633 hypothetical protein; hypothetical protein 641524 7115460 Mchl_0644 Methylobacterium extorquens CM4 hypothetical protein YP_002419494.1 639707 D 440085 CDS YP_002419495.1 218528679 7115461 641478..642146 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mex:Mext_0634 lytic transglycosylase catalytic; lytic transglycosylase 642146 7115461 Mchl_0645 Methylobacterium extorquens CM4 lytic transglycosylase YP_002419495.1 641478 D 440085 CDS YP_002419496.1 218528680 7115462 complement(642236..642937) 1 NC_011757.1 PFAM: transcriptional regulator; KEGG: mex:Mext_0635 transcriptional regulator domain-containing protein; transcriptional regulator 642937 7115462 Mchl_0646 Methylobacterium extorquens CM4 transcriptional regulator YP_002419496.1 642236 R 440085 CDS YP_002419497.1 218528681 7115463 complement(643159..643605) 1 NC_011757.1 KEGG: mex:Mext_0636 hypothetical protein; hypothetical protein 643605 7115463 Mchl_0647 Methylobacterium extorquens CM4 hypothetical protein YP_002419497.1 643159 R 440085 CDS YP_002419498.1 218528682 7115464 complement(643602..644663) 1 NC_011757.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar biosynthesis protein FlhB 644663 flhB 7115464 flhB Methylobacterium extorquens CM4 flagellar biosynthesis protein FlhB YP_002419498.1 643602 R 440085 CDS YP_002419499.1 218528683 7115465 complement(644707..645786) 1 NC_011757.1 PFAM: flagellar motor switch protein FliG; KEGG: mex:Mext_0638 flagellar motor switch protein FliG; flagellar motor switch protein FliG 645786 7115465 Mchl_0649 Methylobacterium extorquens CM4 flagellar motor switch protein FliG YP_002419499.1 644707 R 440085 CDS YP_002419500.1 218528684 7115466 complement(645809..646135) 1 NC_011757.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: mex:Mext_0639 flagellar motor switch protein FliN; flagellar motor switch protein FliN 646135 7115466 Mchl_0650 Methylobacterium extorquens CM4 flagellar motor switch protein FliN YP_002419500.1 645809 R 440085 CDS YP_002419501.1 218528685 7115467 646336..646608 1 NC_011757.1 KEGG: mex:Mext_0640 hypothetical protein; hypothetical protein 646608 7115467 Mchl_0651 Methylobacterium extorquens CM4 hypothetical protein YP_002419501.1 646336 D 440085 CDS YP_002419502.1 218528686 7115468 complement(646622..646918) 1 NC_011757.1 KEGG: mex:Mext_0641 hypothetical protein; hypothetical protein 646918 7115468 Mchl_0652 Methylobacterium extorquens CM4 hypothetical protein YP_002419502.1 646622 R 440085 CDS YP_002419503.1 218528687 7115469 complement(646902..647924) 1 NC_011757.1 PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: mex:Mext_0642 flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein 647924 7115469 Mchl_0653 Methylobacterium extorquens CM4 surface presentation of antigens (SPOA) protein YP_002419503.1 646902 R 440085 CDS YP_002419504.1 218528688 7115470 complement(647939..648814) 1 NC_011757.1 KEGG: mex:Mext_0643 chemotaxis MotA protein; chemotaxis MotA protein 648814 7115470 Mchl_0654 Methylobacterium extorquens CM4 chemotaxis MotA protein YP_002419504.1 647939 R 440085 CDS YP_002419505.1 218528689 7115471 649013..649573 1 NC_011757.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 649573 7115471 Mchl_0655 Methylobacterium extorquens CM4 ATP-dependent protease peptidase subunit YP_002419505.1 649013 D 440085 CDS YP_002419506.1 218528690 7115472 649684..650997 1 NC_011757.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 650997 hslU 7115472 hslU Methylobacterium extorquens CM4 ATP-dependent protease ATP-binding subunit HslU YP_002419506.1 649684 D 440085 CDS YP_002419507.1 218528691 7115473 651000..651890 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_0646 hypothetical protein; hypothetical protein 651890 7115473 Mchl_0657 Methylobacterium extorquens CM4 hypothetical protein YP_002419507.1 651000 D 440085 CDS YP_002419508.1 218528692 7115474 complement(651924..652985) 1 NC_011757.1 KEGG: mex:Mext_0647 hypothetical protein; hypothetical protein 652985 7115474 Mchl_0658 Methylobacterium extorquens CM4 hypothetical protein YP_002419508.1 651924 R 440085 CDS YP_002419509.1 218528693 7115475 complement(653035..654120) 1 NC_011757.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mex:Mext_0648 Rieske (2Fe-2S) domain-containing protein; Rieske (2Fe-2S) domain-containing protein 654120 7115475 Mchl_0659 Methylobacterium extorquens CM4 Rieske (2Fe-2S) domain-containing protein YP_002419509.1 653035 R 440085 CDS YP_002419510.1 218528694 7115476 complement(654485..654949) 1 NC_011757.1 KEGG: mex:Mext_0649 hypothetical protein; hypothetical protein 654949 7115476 Mchl_0660 Methylobacterium extorquens CM4 hypothetical protein YP_002419510.1 654485 R 440085 CDS YP_002419511.1 218528695 7115477 655290..655511 1 NC_011757.1 KEGG: mex:Mext_0650 hypothetical protein; hypothetical protein 655511 7115477 Mchl_0661 Methylobacterium extorquens CM4 hypothetical protein YP_002419511.1 655290 D 440085 CDS YP_002419512.1 218528696 7115478 655530..657092 1 NC_011757.1 KEGG: mex:Mext_0651 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle protein 657092 7115478 Mchl_0662 Methylobacterium extorquens CM4 signal recognition particle protein YP_002419512.1 655530 D 440085 CDS YP_002419513.1 218528697 7115479 657089..657436 1 NC_011757.1 TIGRFAM: chorismate mutase; PFAM: chorismate mutase; KEGG: mex:Mext_0652 chorismate mutase; chorismate mutase 657436 7115479 Mchl_0663 Methylobacterium extorquens CM4 chorismate mutase YP_002419513.1 657089 D 440085 CDS YP_002419514.1 218528698 7115480 657436..657798 1 NC_011757.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 657798 rpsP 7115480 rpsP Methylobacterium extorquens CM4 30S ribosomal protein S16 YP_002419514.1 657436 D 440085 CDS YP_002419515.1 218528699 7115481 657923..658594 1 NC_011757.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 658594 rimM 7115481 rimM Methylobacterium extorquens CM4 16S rRNA-processing protein RimM YP_002419515.1 657923 D 440085 CDS YP_002419516.1 218528700 7115482 complement(658602..659396) 1 NC_011757.1 KEGG: mex:Mext_0655 hypothetical protein; hypothetical protein 659396 7115482 Mchl_0666 Methylobacterium extorquens CM4 hypothetical protein YP_002419516.1 658602 R 440085 CDS YP_002419517.1 218528701 7115483 complement(659465..660196) 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_0656 methyltransferase type 11; type 11 methyltransferase 660196 7115483 Mchl_0667 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002419517.1 659465 R 440085 CDS YP_002419518.1 218528702 7115484 660306..660623 1 NC_011757.1 KEGG: mex:Mext_0657 hypothetical protein; hypothetical protein 660623 7115484 Mchl_0668 Methylobacterium extorquens CM4 hypothetical protein YP_002419518.1 660306 D 440085 CDS YP_002419519.1 218528703 7115485 660733..661455 1 NC_011757.1 KEGG: mex:Mext_0658 tRNA (guanine-N1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; tRNA (guanine-N1)-methyltransferase 661455 7115485 Mchl_0669 Methylobacterium extorquens CM4 tRNA (guanine-N1)-methyltransferase YP_002419519.1 660733 D 440085 CDS YP_002419520.1 218528704 7115486 661629..662804 1 NC_011757.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 662804 7115486 Mchl_0670 Methylobacterium extorquens CM4 phosphoserine aminotransferase YP_002419520.1 661629 D 440085 CDS YP_002419521.1 218528705 7115487 complement(662669..662944) 1 NC_011757.1 hypothetical protein 662944 7115487 Mchl_0671 Methylobacterium extorquens CM4 hypothetical protein YP_002419521.1 662669 R 440085 CDS YP_002419522.1 218528706 7115488 662962..664569 1 NC_011757.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 664569 7115488 Mchl_0672 Methylobacterium extorquens CM4 D-3-phosphoglycerate dehydrogenase YP_002419522.1 662962 D 440085 CDS YP_002419523.1 218528707 7115489 664694..664897 1 NC_011757.1 PFAM: Domain of unknown function DUF1902; KEGG: mex:Mext_0661 hypothetical protein; hypothetical protein 664897 7115489 Mchl_0673 Methylobacterium extorquens CM4 hypothetical protein YP_002419523.1 664694 D 440085 CDS YP_002419524.1 218528708 7115490 665040..666137 1 NC_011757.1 KEGG: mex:Mext_0662 aIF-2BI family translation initiation factor; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; translation initiation factor, aIF-2BI family 666137 7115490 Mchl_0674 Methylobacterium extorquens CM4 translation initiation factor, aIF-2BI family YP_002419524.1 665040 D 440085 CDS YP_002419525.1 218528709 7115491 complement(666149..666496) 1 NC_011757.1 KEGG: mex:Mext_0663 DNA-binding protein; DNA-binding protein 666496 7115491 Mchl_0675 Methylobacterium extorquens CM4 DNA-binding protein YP_002419525.1 666149 R 440085 CDS YP_002419526.1 218528710 7115492 complement(666562..667980) 1 NC_011757.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mex:Mext_0664 MATE efflux family protein; MATE efflux family protein 667980 7115492 Mchl_0676 Methylobacterium extorquens CM4 MATE efflux family protein YP_002419526.1 666562 R 440085 CDS YP_002419527.1 218528711 7115493 complement(668006..669862) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_0665 ABC transporter; ABC transporter 669862 7115493 Mchl_0677 Methylobacterium extorquens CM4 ABC transporter YP_002419527.1 668006 R 440085 CDS YP_002419528.1 218528712 7115494 669988..670437 1 NC_011757.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mex:Mext_0666 tRNA/rRNA methyltransferase (SpoU); tRNA/rRNA methyltransferase SpoU 670437 7115494 Mchl_0678 Methylobacterium extorquens CM4 tRNA/rRNA methyltransferase SpoU YP_002419528.1 669988 D 440085 CDS YP_002419529.1 218528713 7115495 670684..672381 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0667 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 672381 7115495 Mchl_0679 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002419529.1 670684 D 440085 CDS YP_002419530.1 218528714 7115496 672644..673783 1 NC_011757.1 PFAM: PspA/IM30 family protein; KEGG: mex:Mext_0668 PspA/IM30 family protein; phage shock protein PspA 673783 7115496 Mchl_0680 Methylobacterium extorquens CM4 phage shock protein PspA YP_002419530.1 672644 D 440085 CDS YP_002419531.1 218528715 7115497 673780..674448 1 NC_011757.1 PFAM: protein of unknown function DUF1449; KEGG: mex:Mext_0669 hypothetical protein; hypothetical protein 674448 7115497 Mchl_0681 Methylobacterium extorquens CM4 hypothetical protein YP_002419531.1 673780 D 440085 CDS YP_002419532.1 218528716 7115498 674486..676192 1 NC_011757.1 PFAM: band 7 protein; KEGG: rec:RHECIAT_CH0003358 hypothetical protein; band 7 protein 676192 7115498 Mchl_0682 Methylobacterium extorquens CM4 band 7 protein YP_002419532.1 674486 D 440085 CDS YP_002419533.1 218528717 7115499 676385..678571 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_0672 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 678571 7115499 Mchl_0683 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002419533.1 676385 D 440085 CDS YP_002419534.1 218528718 7115500 678615..679538 1 NC_011757.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 679538 7115500 Mchl_0684 Methylobacterium extorquens CM4 coproporphyrinogen III oxidase YP_002419534.1 678615 D 440085 CDS YP_002419535.1 218528719 7115501 679586..680707 1 NC_011757.1 KEGG: mex:Mext_0674 deoxyribonuclease; deoxyribonuclease 680707 7115501 Mchl_0685 Methylobacterium extorquens CM4 deoxyribonuclease YP_002419535.1 679586 D 440085 CDS YP_002419536.1 218528720 7115502 complement(680858..682135) 1 NC_011757.1 KEGG: mex:Mext_0675 aspartate aminotransferase; GntR family transcriptional regulator 682135 7115502 Mchl_0686 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002419536.1 680858 R 440085 CDS YP_002419537.1 218528721 7115503 682520..683200 1 NC_011757.1 PFAM: transcriptional regulator; KEGG: mex:Mext_0676 transcriptional regulator domain-containing protein; transcriptional regulator 683200 7115503 Mchl_0687 Methylobacterium extorquens CM4 transcriptional regulator YP_002419537.1 682520 D 440085 CDS YP_002419538.1 218528722 7115505 complement(685227..685526) 1 NC_011757.1 PFAM: type IV pilus assembly PilZ; KEGG: mex:Mext_0678 type IV pilus assembly PilZ; type IV pilus assembly PilZ 685526 7115505 Mchl_0689 Methylobacterium extorquens CM4 type IV pilus assembly PilZ YP_002419538.1 685227 R 440085 CDS YP_002419539.1 218528723 7115506 685729..686298 1 NC_011757.1 KEGG: mex:Mext_0679 hypothetical protein; hypothetical protein 686298 7115506 Mchl_0690 Methylobacterium extorquens CM4 hypothetical protein YP_002419539.1 685729 D 440085 CDS YP_002419540.1 218528724 7115507 686471..687724 1 NC_011757.1 PFAM: protein of unknown function DUF1217; KEGG: mex:Mext_0680 hypothetical protein; hypothetical protein 687724 7115507 Mchl_0691 Methylobacterium extorquens CM4 hypothetical protein YP_002419540.1 686471 D 440085 CDS YP_002419541.1 218528725 7115508 687730..688458 1 NC_011757.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: mex:Mext_0681 flagellar basal body rod protein; flagellar basal body rod protein 688458 7115508 Mchl_0692 Methylobacterium extorquens CM4 flagellar basal body rod protein YP_002419541.1 687730 D 440085 CDS YP_002419542.1 218528726 7115509 688463..689791 1 NC_011757.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 689791 fliI 7115509 fliI Methylobacterium extorquens CM4 flagellum-specific ATP synthase YP_002419542.1 688463 D 440085 CDS YP_002419543.1 218528727 7115510 689874..691085 1 NC_011757.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 691085 flgE 7115510 flgE Methylobacterium extorquens CM4 flagellar hook protein FlgE YP_002419543.1 689874 D 440085 CDS YP_002419544.1 218528728 7115511 691164..692627 1 NC_011757.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 692627 flgK 7115511 flgK Methylobacterium extorquens CM4 flagellar hook-associated protein FlgK YP_002419544.1 691164 D 440085 CDS YP_002419545.1 218528729 7118014 692635..693687 1 NC_011757.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL 693687 flgL 7118014 flgL Methylobacterium extorquens CM4 flagellar hook-associated protein FlgL YP_002419545.1 692635 D 440085 CDS YP_002419546.1 218528730 7116550 693728..694078 1 NC_011757.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF 694078 flaF 7116550 flaF Methylobacterium extorquens CM4 flagellar biosynthesis regulatory protein FlaF YP_002419546.1 693728 D 440085 CDS YP_002419547.1 218528731 7116551 694089..694610 1 NC_011757.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT 694610 flbT 7116551 flbT Methylobacterium extorquens CM4 flagellar biosynthesis repressor FlbT YP_002419547.1 694089 D 440085 CDS YP_002419548.1 218528732 7116552 694617..695033 1 NC_011757.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein 695033 flgD 7116552 flgD Methylobacterium extorquens CM4 flagellar basal body rod modification protein YP_002419548.1 694617 D 440085 CDS YP_002419549.1 218528733 7116553 695164..695430 1 NC_011757.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ 695430 fliQ 7116553 fliQ Methylobacterium extorquens CM4 flagellar biosynthesis protein FliQ YP_002419549.1 695164 D 440085 CDS YP_002419550.1 218528734 7116554 695761..697842 1 NC_011757.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 697842 flhA 7116554 flhA Methylobacterium extorquens CM4 flagellar biosynthesis protein FlhA YP_002419550.1 695761 D 440085 CDS YP_002419551.1 218528735 7116555 697839..698609 1 NC_011757.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium has one thick and several thin flagella; the Bradyrhizobium protein in this cluster are associated with the thin flagella; flagellar biosynthesis protein FliR 698609 fliR 7116555 fliR Methylobacterium extorquens CM4 flagellar biosynthesis protein FliR YP_002419551.1 697839 D 440085 CDS YP_002419552.1 218528736 7116556 698615..699025 1 NC_011757.1 KEGG: mex:Mext_0692 hypothetical protein; hypothetical protein 699025 7116556 Mchl_0703 Methylobacterium extorquens CM4 hypothetical protein YP_002419552.1 698615 D 440085 CDS YP_002419553.1 218528737 7116557 699101..699583 1 NC_011757.1 KEGG: mex:Mext_0693 hypothetical protein; hypothetical protein 699583 7116557 Mchl_0704 Methylobacterium extorquens CM4 hypothetical protein YP_002419553.1 699101 D 440085 CDS YP_002419554.1 218528738 7116558 699589..699921 1 NC_011757.1 KEGG: mex:Mext_0694 hypothetical protein; hypothetical protein 699921 7116558 Mchl_0705 Methylobacterium extorquens CM4 hypothetical protein YP_002419554.1 699589 D 440085 CDS YP_002419555.1 218528739 7116559 699925..700371 1 NC_011757.1 KEGG: mex:Mext_0695 hypothetical protein; hypothetical protein 700371 7116559 Mchl_0706 Methylobacterium extorquens CM4 hypothetical protein YP_002419555.1 699925 D 440085 CDS YP_002419556.1 218528740 7116560 700467..701360 1 NC_011757.1 PFAM: dihydrodipicolinate synthetase; KEGG: mex:Mext_0696 dihydrodipicolinate synthetase; dihydrodipicolinate synthetase 701360 7116560 Mchl_0707 Methylobacterium extorquens CM4 dihydrodipicolinate synthetase YP_002419556.1 700467 D 440085 CDS YP_002419557.1 218528741 7116561 701462..702448 1 NC_011757.1 KEGG: mex:Mext_0697 hypothetical protein; hypothetical protein 702448 7116561 Mchl_0708 Methylobacterium extorquens CM4 hypothetical protein YP_002419557.1 701462 D 440085 CDS YP_002419558.1 218528742 7116562 complement(702464..702805) 1 NC_011757.1 PFAM: protein of unknown function DUF1491; KEGG: mex:Mext_0698 hypothetical protein; hypothetical protein 702805 7116562 Mchl_0709 Methylobacterium extorquens CM4 hypothetical protein YP_002419558.1 702464 R 440085 CDS YP_002419559.1 218528743 7116563 complement(702901..703653) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_0699 peptidoglycan binding domain-containing protein; peptidoglycan-binding protein 703653 7116563 Mchl_0710 Methylobacterium extorquens CM4 peptidoglycan-binding protein YP_002419559.1 702901 R 440085 CDS YP_002419560.1 218528744 7116564 complement(703697..705637) 1 NC_011757.1 KEGG: mex:Mext_0700 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; SMART: PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 705637 7116564 Mchl_0711 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002419560.1 703697 R 440085 CDS YP_002419561.1 218528745 7116565 706016..706348 1 NC_011757.1 KEGG: mex:Mext_0701 hypothetical protein; hypothetical protein 706348 7116565 Mchl_0712 Methylobacterium extorquens CM4 hypothetical protein YP_002419561.1 706016 D 440085 CDS YP_002419562.1 218528746 7116566 706499..707542 1 NC_011757.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: mex:Mext_0702 cytochrome d ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 707542 7116566 Mchl_0713 Methylobacterium extorquens CM4 cytochrome d ubiquinol oxidase subunit II YP_002419562.1 706499 D 440085 CDS YP_002419563.1 218528747 7116567 707539..707637 1 NC_011757.1 KEGG: mpo:Mpop_0676 hypothetical protein; hypothetical protein 707637 7116567 Mchl_0714 Methylobacterium extorquens CM4 hypothetical protein YP_002419563.1 707539 D 440085 CDS YP_002419564.1 218528748 7116568 complement(707651..707776) 1 NC_011757.1 hypothetical protein 707776 7116568 Mchl_0715 Methylobacterium extorquens CM4 hypothetical protein YP_002419564.1 707651 R 440085 CDS YP_002419565.1 218528749 7116569 complement(707773..709002) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0703 major facilitator transporter; major facilitator superfamily protein 709002 7116569 Mchl_0716 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419565.1 707773 R 440085 CDS YP_002419566.1 218528750 7116570 complement(709062..710279) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0704 major facilitator transporter; major facilitator superfamily protein 710279 7116570 Mchl_0717 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419566.1 709062 R 440085 CDS YP_002419567.1 218528751 7116571 710387..710887 1 NC_011757.1 PFAM: helix-turn-helix HxlR type; KEGG: mex:Mext_0705 helix-turn-helix HxlR type; HxlR family transcriptional regulator 710887 7116571 Mchl_0718 Methylobacterium extorquens CM4 HxlR family transcriptional regulator YP_002419567.1 710387 D 440085 CDS YP_002419568.1 218528752 7116572 711138..713630 1 NC_011757.1 KEGG: mex:Mext_0706 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; penicillin-binding protein, 1A family 713630 7116572 Mchl_0719 Methylobacterium extorquens CM4 penicillin-binding protein, 1A family YP_002419568.1 711138 D 440085 CDS YP_002419569.1 218528753 7116573 713837..715534 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0707 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 715534 7116573 Mchl_0720 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002419569.1 713837 D 440085 CDS YP_002419570.1 218528754 7116574 complement(715648..717135) 1 NC_011757.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 717135 7116574 Mchl_0721 Methylobacterium extorquens CM4 AMP nucleosidase YP_002419570.1 715648 R 440085 CDS YP_002419571.1 218528755 7116575 717317..717823 1 NC_011757.1 PFAM: protein of unknown function UPF0066; KEGG: mex:Mext_0709 hypothetical protein; hypothetical protein 717823 7116575 Mchl_0722 Methylobacterium extorquens CM4 hypothetical protein YP_002419571.1 717317 D 440085 CDS YP_002419572.1 218528756 7116576 complement(717843..719198) 1 NC_011757.1 KEGG: mex:Mext_0710 cellulose biosynthesis protein CelD; cellulose biosynthesis protein CelD 719198 7116576 Mchl_0723 Methylobacterium extorquens CM4 cellulose biosynthesis protein CelD YP_002419572.1 717843 R 440085 CDS YP_002419573.1 218528757 7116577 complement(719362..720432) 1 NC_011757.1 PFAM: protein of unknown function DUF201; KEGG: mex:Mext_0711 hypothetical protein; hypothetical protein 720432 7116577 Mchl_0724 Methylobacterium extorquens CM4 hypothetical protein YP_002419573.1 719362 R 440085 CDS YP_002419574.1 218528758 7116578 complement(720676..721107) 1 NC_011757.1 PFAM: protein of unknown function DUF1810; KEGG: mex:Mext_0712 hypothetical protein; hypothetical protein 721107 7116578 Mchl_0725 Methylobacterium extorquens CM4 hypothetical protein YP_002419574.1 720676 R 440085 CDS YP_002419575.1 218528759 7116579 complement(721169..722062) 1 NC_011757.1 PFAM: histone deacetylase superfamily; KEGG: mex:Mext_0713 histone deacetylase superfamily protein; histone deacetylase superfamily protein 722062 7116579 Mchl_0726 Methylobacterium extorquens CM4 histone deacetylase superfamily protein YP_002419575.1 721169 R 440085 CDS YP_002419576.1 218528760 7116580 722178..723362 1 NC_011757.1 KEGG: mex:Mext_0714 ceramide glucosyltransferase; ceramide glucosyltransferase 723362 7116580 Mchl_0727 Methylobacterium extorquens CM4 ceramide glucosyltransferase YP_002419576.1 722178 D 440085 CDS YP_002419577.1 218528761 7116581 723864..725411 1 NC_011757.1 KEGG: mex:Mext_0715 chromosome segregation ATPase-like protein; chromosome segregation ATPase-like protein 725411 7116581 Mchl_0728 Methylobacterium extorquens CM4 chromosome segregation ATPase-like protein YP_002419577.1 723864 D 440085 CDS YP_002419578.1 218528762 7116582 725468..725959 1 NC_011757.1 KEGG: mex:Mext_0716 hypothetical protein; hypothetical protein 725959 7116582 Mchl_0729 Methylobacterium extorquens CM4 hypothetical protein YP_002419578.1 725468 D 440085 CDS YP_002419579.1 218528763 7116583 725977..726483 1 NC_011757.1 KEGG: mex:Mext_0717 hypothetical protein; hypothetical protein 726483 7116583 Mchl_0730 Methylobacterium extorquens CM4 hypothetical protein YP_002419579.1 725977 D 440085 CDS YP_002419580.1 218528764 7116584 726701..728077 1 NC_011757.1 TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region; KEGG: mex:Mext_0718 ethanolamine transproter; ethanolamine transporter 728077 7116584 Mchl_0731 Methylobacterium extorquens CM4 ethanolamine transporter YP_002419580.1 726701 D 440085 CDS YP_002419581.1 218528765 7116585 complement(728284..729210) 1 NC_011757.1 PFAM: fatty acid desaturase; KEGG: mex:Mext_0719 fatty acid desaturase; fatty acid desaturase 729210 7116585 Mchl_0732 Methylobacterium extorquens CM4 fatty acid desaturase YP_002419581.1 728284 R 440085 CDS YP_002419582.1 218528766 7116586 729300..729620 1 NC_011757.1 PFAM: regulatory protein ArsR; Helix-turn-helix type 11 domain protein; KEGG: mex:Mext_0720 regulatory protein ArsR; ArsR family transcriptional regulator 729620 7116586 Mchl_0733 Methylobacterium extorquens CM4 ArsR family transcriptional regulator YP_002419582.1 729300 D 440085 CDS YP_002419583.1 218528767 7116587 730227..730928 1 NC_011757.1 PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_0721 glutamine amidotransferase class-I; class I glutamine amidotransferase 730928 7116587 Mchl_0734 Methylobacterium extorquens CM4 class I glutamine amidotransferase YP_002419583.1 730227 D 440085 CDS YP_002419584.1 218528768 7116588 complement(730930..731946) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_0722 aldo/keto reductase; aldo/keto reductase 731946 7116588 Mchl_0735 Methylobacterium extorquens CM4 aldo/keto reductase YP_002419584.1 730930 R 440085 CDS YP_002419585.1 218528769 7116589 732095..733006 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator; KEGG: mex:Mext_0723 AraC-like transcriptional regulator; AraC family transcriptional regulator 733006 7116589 Mchl_0736 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002419585.1 732095 D 440085 CDS YP_002419586.1 218528770 7116592 734698..735279 1 NC_011757.1 KEGG: mex:Mext_0725 DedA family protein; DedA family protein 735279 7116592 Mchl_0738 Methylobacterium extorquens CM4 DedA family protein YP_002419586.1 734698 D 440085 CDS YP_002419587.1 218528771 7116593 735276..735800 1 NC_011757.1 PFAM: disulfide bond formation protein DsbB; KEGG: mex:Mext_0726 disulphide bond formation protein DsbB; disulfide bond formation protein DsbB 735800 7116593 Mchl_0739 Methylobacterium extorquens CM4 disulfide bond formation protein DsbB YP_002419587.1 735276 D 440085 CDS YP_002419588.1 218528772 7116594 complement(735764..736381) 1 NC_011757.1 PFAM: ParB-like nuclease; KEGG: mex:Mext_0727 ParB-like nuclease; ParB-like nuclease 736381 7116594 Mchl_0740 Methylobacterium extorquens CM4 ParB-like nuclease YP_002419588.1 735764 R 440085 CDS YP_002419589.1 218528773 7116595 736764..737954 1 NC_011757.1 PFAM: acyltransferase 3; KEGG: mex:Mext_0728 acyltransferase 3; acyltransferase 3 737954 7116595 Mchl_0741 Methylobacterium extorquens CM4 acyltransferase 3 YP_002419589.1 736764 D 440085 CDS YP_002419590.1 218528774 7116596 complement(737970..738392) 1 NC_011757.1 PFAM: protein of unknown function DUF55; KEGG: mex:Mext_0729 hypothetical protein; hypothetical protein 738392 7116596 Mchl_0742 Methylobacterium extorquens CM4 hypothetical protein YP_002419590.1 737970 R 440085 CDS YP_002419591.1 218528775 7116597 complement(738494..739507) 1 NC_011757.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 739507 gpsA 7116597 gpsA Methylobacterium extorquens CM4 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002419591.1 738494 R 440085 CDS YP_002419592.1 218528776 7116599 740400..741539 1 NC_011757.1 KEGG: mex:Mext_0731 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; hypothetical protein; SMART: PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 741539 7116599 Mchl_0745 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor YP_002419592.1 740400 D 440085 CDS YP_002419593.1 218528777 7116600 complement(741556..742599) 1 NC_011757.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 742599 7116600 Mchl_0746 Methylobacterium extorquens CM4 DNA-binding/iron metalloprotein/AP endonuclease YP_002419593.1 741556 R 440085 CDS YP_002419594.1 218528778 7116601 742777..743487 1 NC_011757.1 KEGG: mex:Mext_0733 uroporphyrinogen III synthase HEM4; uroporphyrinogen III synthase HEM4 743487 7116601 Mchl_0747 Methylobacterium extorquens CM4 uroporphyrinogen III synthase HEM4 YP_002419594.1 742777 D 440085 CDS YP_002419595.1 218528779 7116602 743643..745931 1 NC_011757.1 KEGG: mex:Mext_0734 hypothetical protein; hypothetical protein 745931 7116602 Mchl_0748 Methylobacterium extorquens CM4 hypothetical protein YP_002419595.1 743643 D 440085 CDS YP_002419596.1 218528780 7116603 746049..747584 1 NC_011757.1 PFAM: HemY domain protein; KEGG: mex:Mext_0735 HemY domain-containing protein; HemY domain-containing protein 747584 7116603 Mchl_0749 Methylobacterium extorquens CM4 HemY domain-containing protein YP_002419596.1 746049 D 440085 CDS YP_002419597.1 218528781 7116605 748223..748504 1 NC_011757.1 KEGG: mex:Mext_0807 hypothetical protein; hypothetical protein 748504 7116605 Mchl_0750 Methylobacterium extorquens CM4 hypothetical protein YP_002419597.1 748223 D 440085 CDS YP_002419598.1 218528782 7116606 complement(748535..748765) 1 NC_011757.1 KEGG: mex:Mext_0808 hypothetical protein; hypothetical protein 748765 7116606 Mchl_0751 Methylobacterium extorquens CM4 hypothetical protein YP_002419598.1 748535 R 440085 CDS YP_002419599.1 218528783 7116607 749239..751389 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0809 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 751389 7116607 Mchl_0752 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002419599.1 749239 D 440085 CDS YP_002419600.1 218528784 7116608 751513..752163 1 NC_011757.1 KEGG: mex:Mext_0810 hypothetical protein; hypothetical protein 752163 7116608 Mchl_0753 Methylobacterium extorquens CM4 hypothetical protein YP_002419600.1 751513 D 440085 CDS YP_002419601.1 218528785 7116609 753248..755392 1 NC_011757.1 PFAM: helicase; KEGG: mex:Mext_0811 helicase domain-containing protein; helicase 755392 7116609 Mchl_0754 Methylobacterium extorquens CM4 helicase YP_002419601.1 753248 D 440085 CDS YP_002419602.1 218528786 7116616 complement(761781..762950) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: mex:Mext_1007 NADH dehydrogenase; NADH dehydrogenase (ubiquinone) 762950 7116616 Mchl_0755 Methylobacterium extorquens CM4 NADH dehydrogenase (ubiquinone) YP_002419602.1 761781 R 440085 CDS YP_002419603.1 218528787 7116617 complement(763202..763870) 1 NC_011757.1 KEGG: mex:Mext_1008 hypothetical protein; hypothetical protein 763870 7116617 Mchl_0756 Methylobacterium extorquens CM4 hypothetical protein YP_002419603.1 763202 R 440085 CDS YP_002419604.1 218528788 7116618 764113..765282 1 NC_011757.1 PFAM: proton/sugar symporter LacY; major facilitator superfamily MFS_1; KEGG: mex:Mext_1009 major facilitator transporter; major facilitator superfamily protein 765282 7116618 Mchl_0757 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419604.1 764113 D 440085 CDS YP_002419605.1 218528789 7116619 765366..767543 1 NC_011757.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 767543 7116619 Mchl_0758 Methylobacterium extorquens CM4 primosome assembly protein PriA YP_002419605.1 765366 D 440085 CDS YP_002419606.1 218528790 7116620 767628..767990 1 NC_011757.1 KEGG: mex:Mext_1011 hypothetical protein; hypothetical protein 767990 7116620 Mchl_0759 Methylobacterium extorquens CM4 hypothetical protein YP_002419606.1 767628 D 440085 CDS YP_002419607.1 218528791 7116621 complement(768080..768460) 1 NC_011757.1 KEGG: mex:Mext_1012 hypothetical protein; hypothetical protein 768460 7116621 Mchl_0760 Methylobacterium extorquens CM4 hypothetical protein YP_002419607.1 768080 R 440085 CDS YP_002419608.1 218528792 7116622 complement(768882..769133) 1 NC_011757.1 KEGG: mex:Mext_1013 hypothetical protein; hypothetical protein 769133 7116622 Mchl_0761 Methylobacterium extorquens CM4 hypothetical protein YP_002419608.1 768882 R 440085 CDS YP_002419609.1 218528793 7116623 complement(769251..770261) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1014 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 770261 7116623 Mchl_0762 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419609.1 769251 R 440085 CDS YP_002419610.1 218528794 7116624 complement(770407..771018) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_1015 isochorismatase hydrolase; isochorismatase hydrolase 771018 7116624 Mchl_0763 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002419610.1 770407 R 440085 CDS YP_002419611.1 218528795 7116625 complement(771051..772223) 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_1016 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 772223 7116625 Mchl_0764 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES domain-containing protein YP_002419611.1 771051 R 440085 CDS YP_002419612.1 218528796 7116626 complement(772353..773006) 1 NC_011757.1 KEGG: mex:Mext_1017 hypothetical protein; hypothetical protein 773006 7116626 Mchl_0765 Methylobacterium extorquens CM4 hypothetical protein YP_002419612.1 772353 R 440085 CDS YP_002419613.1 218528797 7116627 773182..774039 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1018 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 774039 7116627 Mchl_0766 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419613.1 773182 D 440085 CDS YP_002419614.1 218528798 7116628 774107..775099 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1019 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 775099 7116628 Mchl_0767 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419614.1 774107 D 440085 CDS YP_002419615.1 218528799 7116629 775182..775361 1 NC_011757.1 KEGG: mex:Mext_1020 hypothetical protein; hypothetical protein 775361 7116629 Mchl_0768 Methylobacterium extorquens CM4 hypothetical protein YP_002419615.1 775182 D 440085 CDS YP_002419616.1 218528800 7116630 complement(775499..777130) 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_1021 hypothetical protein; ABC transporter 777130 7116630 Mchl_0769 Methylobacterium extorquens CM4 ABC transporter YP_002419616.1 775499 R 440085 CDS YP_002419617.1 218528801 7115676 complement(777291..777770) 1 NC_011757.1 KEGG: mex:Mext_1022 hypothetical protein; hypothetical protein 777770 7115676 Mchl_0770 Methylobacterium extorquens CM4 hypothetical protein YP_002419617.1 777291 R 440085 CDS YP_002419618.1 218528802 7115764 783659..784378 1 NC_011757.1 KEGG:.; hypothetical protein 784378 7115764 Mchl_0771 Methylobacterium extorquens CM4 hypothetical protein YP_002419618.1 783659 D 440085 CDS YP_002419619.1 218528803 7115765 784861..787176 1 NC_011757.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: mex:Mext_0813 RNA-binding S1 domain-containing protein; RNA binding S1 domain-containing protein 787176 7115765 Mchl_0772 Methylobacterium extorquens CM4 RNA binding S1 domain-containing protein YP_002419619.1 784861 D 440085 CDS YP_002419620.1 218528804 7115766 complement(787163..787471) 1 NC_011757.1 KEGG: mex:Mext_0814 hypothetical protein; hypothetical protein 787471 7115766 Mchl_0773 Methylobacterium extorquens CM4 hypothetical protein YP_002419620.1 787163 R 440085 CDS YP_002419621.1 218528805 7115767 788030..788683 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_0815 ABC transporter related; ABC transporter 788683 7115767 Mchl_0774 Methylobacterium extorquens CM4 ABC transporter YP_002419621.1 788030 D 440085 CDS YP_002419622.1 218528806 7115768 788833..790077 1 NC_011757.1 KEGG: mex:Mext_0816 capsule polysaccharide export protein-like protein; capsule polysaccharide export protein-like protein 790077 7115768 Mchl_0775 Methylobacterium extorquens CM4 capsule polysaccharide export protein-like protein YP_002419622.1 788833 D 440085 CDS YP_002419623.1 218528807 7115769 complement(790086..790802) 1 NC_011757.1 KEGG: mex:Mext_0817 hypothetical protein; hypothetical protein 790802 7115769 Mchl_0776 Methylobacterium extorquens CM4 hypothetical protein YP_002419623.1 790086 R 440085 CDS YP_002419624.1 218528808 7115770 complement(790840..791148) 1 NC_011757.1 KEGG: mex:Mext_0818 hypothetical protein; hypothetical protein 791148 7115770 Mchl_0777 Methylobacterium extorquens CM4 hypothetical protein YP_002419624.1 790840 R 440085 CDS YP_002419625.1 218528809 7115771 791349..793490 1 NC_011757.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 793490 flhA 7115771 flhA Methylobacterium extorquens CM4 flagellar biosynthesis protein FlhA YP_002419625.1 791349 D 440085 CDS YP_002419626.1 218528810 7115772 793746..795422 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Cache type 2 domain protein; KEGG: mex:Mext_0820 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer with Cache sensor 795422 7115772 Mchl_0779 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer with Cache sensor YP_002419626.1 793746 D 440085 CDS YP_002419627.1 218528811 7115773 complement(795574..795714) 1 NC_011757.1 KEGG: mpo:Mpop_0742 hypothetical protein; hypothetical protein 795714 7115773 Mchl_0780 Methylobacterium extorquens CM4 hypothetical protein YP_002419627.1 795574 R 440085 CDS YP_002419628.1 218528812 7115774 complement(795947..796999) 1 NC_011757.1 KEGG: mex:Mext_0821 hypothetical protein; hypothetical protein 796999 7115774 Mchl_0781 Methylobacterium extorquens CM4 hypothetical protein YP_002419628.1 795947 R 440085 CDS YP_002419629.1 218528813 7115775 complement(797356..797760) 1 NC_011757.1 TIGRFAM: flagellar export protein FliJ; KEGG: mex:Mext_0822 flagellar export protein FliJ; flagellar export protein FliJ 797760 7115775 Mchl_0782 Methylobacterium extorquens CM4 flagellar export protein FliJ YP_002419629.1 797356 R 440085 CDS YP_002419630.1 218528814 7115776 complement(797856..799211) 1 NC_011757.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 799211 fliI 7115776 fliI Methylobacterium extorquens CM4 flagellum-specific ATP synthase YP_002419630.1 797856 R 440085 CDS YP_002419631.1 218528815 7115777 799650..800351 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_0824 response regulator receiver; transcriptional regulator 800351 7115777 Mchl_0784 Methylobacterium extorquens CM4 transcriptional regulator YP_002419631.1 799650 D 440085 CDS YP_002419632.1 218528816 7115778 complement(800428..800679) 1 NC_011757.1 KEGG: mex:Mext_0825 hypothetical protein; hypothetical protein 800679 7115778 Mchl_0785 Methylobacterium extorquens CM4 hypothetical protein YP_002419632.1 800428 R 440085 CDS YP_002419633.1 218528817 7115779 complement(800713..801339) 1 NC_011757.1 KEGG: mex:Mext_0826 chloramphenicol acetyltransferase; chloramphenicol acetyltransferase 801339 7115779 Mchl_0786 Methylobacterium extorquens CM4 chloramphenicol acetyltransferase YP_002419633.1 800713 R 440085 CDS YP_002419634.1 218528818 7115780 801415..803748 1 NC_011757.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 803748 7115780 Mchl_0787 Methylobacterium extorquens CM4 malic enzyme YP_002419634.1 801415 D 440085 CDS YP_002419635.1 218528819 7115781 803851..805290 1 NC_011757.1 PFAM: acetamidase/formamidase; KEGG: mex:Mext_0828 acetamidase/formamidase; acetamidase/formamidase 805290 7115781 Mchl_0788 Methylobacterium extorquens CM4 acetamidase/formamidase YP_002419635.1 803851 D 440085 CDS YP_002419636.1 218528820 7115782 complement(805464..805643) 1 NC_011757.1 KEGG: mex:Mext_0829 hypothetical protein; hypothetical protein 805643 7115782 Mchl_0789 Methylobacterium extorquens CM4 hypothetical protein YP_002419636.1 805464 R 440085 CDS YP_002419637.1 218528821 7115783 complement(805723..806607) 1 NC_011757.1 KEGG: mex:Mext_0830 hypothetical protein; hypothetical protein 806607 7115783 Mchl_0790 Methylobacterium extorquens CM4 hypothetical protein YP_002419637.1 805723 R 440085 CDS YP_002419638.1 218528822 7115784 complement(806604..808679) 1 NC_011757.1 PFAM: glycosyl transferase family 2; glycosyl transferase group 1; KEGG: mex:Mext_0831 glycosyl transferase; family 2 glycosyl transferase 808679 7115784 Mchl_0791 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419638.1 806604 R 440085 CDS YP_002419639.1 218528823 7115785 complement(808683..810704) 1 NC_011757.1 KEGG: mex:Mext_0832 hypothetical protein; hypothetical protein 810704 7115785 Mchl_0792 Methylobacterium extorquens CM4 hypothetical protein YP_002419639.1 808683 R 440085 CDS YP_002419640.1 218528824 7115786 complement(810704..811393) 1 NC_011757.1 KEGG: mex:Mext_0833 hypothetical protein; hypothetical protein 811393 7115786 Mchl_0793 Methylobacterium extorquens CM4 hypothetical protein YP_002419640.1 810704 R 440085 CDS YP_002419641.1 218528825 7115787 complement(811589..812974) 1 NC_011757.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mex:Mext_0834 hypothetical protein; hypothetical protein 812974 7115787 Mchl_0794 Methylobacterium extorquens CM4 hypothetical protein YP_002419641.1 811589 R 440085 CDS YP_002419642.1 218528826 7115788 813263..813787 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_0835 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 813787 7115788 Mchl_0795 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002419642.1 813263 D 440085 CDS YP_002419643.1 218528827 7115789 813784..814800 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mex:Mext_0836 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 814800 7115789 Mchl_0796 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002419643.1 813784 D 440085 CDS YP_002419644.1 218528828 7115790 814810..817071 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_0837 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 817071 7115790 Mchl_0797 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002419644.1 814810 D 440085 CDS YP_002419645.1 218528829 7115791 817348..817716 1 NC_011757.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: mpo:Mpop_0761 CrcB protein; CrcB protein 817716 7115791 Mchl_0798 Methylobacterium extorquens CM4 CrcB protein YP_002419645.1 817348 D 440085 CDS YP_002419646.1 218528830 7115792 817728..818165 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_0839 hypothetical protein; hypothetical protein 818165 7115792 Mchl_0799 Methylobacterium extorquens CM4 hypothetical protein YP_002419646.1 817728 D 440085 CDS YP_002419647.1 218528831 7115793 818165..818827 1 NC_011757.1 PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; KEGG: mex:Mext_0840 peptidase M15D VanX D-ala-D-ala dipeptidase; peptidase M15D vanX D-ala-D-ala dipeptidase 818827 7115793 Mchl_0800 Methylobacterium extorquens CM4 peptidase M15D vanX D-ala-D-ala dipeptidase YP_002419647.1 818165 D 440085 CDS YP_002419648.1 218528832 7115794 818996..819271 1 NC_011757.1 KEGG: mex:Mext_0841 hypothetical protein; hypothetical protein 819271 7115794 Mchl_0801 Methylobacterium extorquens CM4 hypothetical protein YP_002419648.1 818996 D 440085 CDS YP_002419649.1 218528833 7115795 819268..819594 1 NC_011757.1 KEGG: mex:Mext_0842 hypothetical protein; hypothetical protein 819594 7115795 Mchl_0802 Methylobacterium extorquens CM4 hypothetical protein YP_002419649.1 819268 D 440085 CDS YP_002419650.1 218528834 7115796 complement(819712..820353) 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_0844 regulatory protein MarR; MarR family transcriptional regulator 820353 7115796 Mchl_0803 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002419650.1 819712 R 440085 CDS YP_002419651.1 218528835 7115797 820600..822777 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_0845 glycosyl transferase; family 2 glycosyl transferase 822777 7115797 Mchl_0804 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002419651.1 820600 D 440085 CDS YP_002419652.1 218528836 7115798 822809..823576 1 NC_011757.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: nucleotidyl transferase; KEGG: mex:Mext_0846 glucose-1-phosphate cytidylyltransferase; glucose-1-phosphate cytidylyltransferase 823576 7115798 Mchl_0805 Methylobacterium extorquens CM4 glucose-1-phosphate cytidylyltransferase YP_002419652.1 822809 D 440085 CDS YP_002419653.1 218528837 7115799 823576..824670 1 NC_011757.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: mex:Mext_0847 CDP-glucose 4,6-dehydratase; CDP-glucose 4,6-dehydratase 824670 7115799 Mchl_0806 Methylobacterium extorquens CM4 CDP-glucose 4,6-dehydratase YP_002419653.1 823576 D 440085 CDS YP_002419654.1 218528838 7115800 824667..825896 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; methyltransferase domain protein; C-methyltransferase; KEGG: mex:Mext_0848 C-methyltransferase; C-methyltransferase 825896 7115800 Mchl_0807 Methylobacterium extorquens CM4 C-methyltransferase YP_002419654.1 824667 D 440085 CDS YP_002419655.1 218528839 7115801 826081..826614 1 NC_011757.1 PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; KEGG: mex:Mext_0849 dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose 3,5-epimerase 826614 7115801 Mchl_0808 Methylobacterium extorquens CM4 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002419655.1 826081 D 440085 CDS YP_002419656.1 218528840 7115802 826611..827651 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: mex:Mext_0850 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 827651 7115802 Mchl_0809 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002419656.1 826611 D 440085 CDS YP_002419657.1 218528841 7115803 complement(827626..828024) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_0851 response regulator receiver; response regulator receiver protein 828024 7115803 Mchl_0810 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419657.1 827626 R 440085 CDS YP_002419658.1 218528842 7115804 complement(828276..829526) 1 NC_011757.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: mex:Mext_0852 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 829526 7115804 Mchl_0811 Methylobacterium extorquens CM4 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002419658.1 828276 R 440085 CDS YP_002419659.1 218528843 7115805 complement(829722..832568) 1 NC_011757.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 832568 7115805 Mchl_0812 Methylobacterium extorquens CM4 glycine dehydrogenase YP_002419659.1 829722 R 440085 CDS YP_002419660.1 218528844 7115806 complement(832742..833104) 1 NC_011757.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 833104 7115806 Mchl_0813 Methylobacterium extorquens CM4 glycine cleavage system protein H YP_002419660.1 832742 R 440085 CDS YP_002419661.1 218528845 7115807 complement(833131..834309) 1 NC_011757.1 TIGRFAM: glycine cleavage system protein T; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; KEGG: mex:Mext_0855 glycine cleavage system protein T; glycine cleavage system protein T 834309 7115807 Mchl_0814 Methylobacterium extorquens CM4 glycine cleavage system protein T YP_002419661.1 833131 R 440085 CDS YP_002419662.1 218528846 7115808 complement(834618..834848) 1 NC_011757.1 KEGG: mex:Mext_0856 hypothetical protein; hypothetical protein 834848 7115808 Mchl_0815 Methylobacterium extorquens CM4 hypothetical protein YP_002419662.1 834618 R 440085 CDS YP_002419663.1 218528847 7115809 834955..836106 1 NC_011757.1 KEGG: mex:Mext_0857 8-amino-7-oxononanoate synthase; TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aminotransferase class I and II; 8-amino-7-oxononanoate synthase 836106 7115809 Mchl_0816 Methylobacterium extorquens CM4 8-amino-7-oxononanoate synthase YP_002419663.1 834955 D 440085 CDS YP_002419664.1 218528848 7115810 complement(836113..836973) 1 NC_011757.1 PFAM: NLP/P60 protein; KEGG: mex:Mext_0858 NLP/P60 protein; NLP/P60 protein 836973 7115810 Mchl_0817 Methylobacterium extorquens CM4 NLP/P60 protein YP_002419664.1 836113 R 440085 CDS YP_002419665.1 218528849 7115811 837286..837657 1 NC_011757.1 KEGG: mex:Mext_0859 hypothetical protein; hypothetical protein 837657 7115811 Mchl_0818 Methylobacterium extorquens CM4 hypothetical protein YP_002419665.1 837286 D 440085 CDS YP_002419666.1 218528850 7115812 complement(837718..838404) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_0860 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 838404 7115812 Mchl_0819 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419666.1 837718 R 440085 CDS YP_002419667.1 218528851 7115813 complement(838467..839183) 1 NC_011757.1 PFAM: MgtC/SapB transporter; KEGG: mex:Mext_0861 MgtC/SapB transporter; MgtC/SapB transporter 839183 7115813 Mchl_0820 Methylobacterium extorquens CM4 MgtC/SapB transporter YP_002419667.1 838467 R 440085 CDS YP_002419668.1 218528852 7115814 839475..840467 1 NC_011757.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase AAA; KEGG: mex:Mext_0862 ATPase; ATPase AAA 840467 7115814 Mchl_0821 Methylobacterium extorquens CM4 ATPase AAA YP_002419668.1 839475 D 440085 CDS YP_002419669.1 218528853 7115815 840473..841402 1 NC_011757.1 KEGG: mex:Mext_0863 hypothetical protein; hypothetical protein 841402 7115815 Mchl_0822 Methylobacterium extorquens CM4 hypothetical protein YP_002419669.1 840473 D 440085 CDS YP_002419670.1 218528854 7115817 841577..842038 1 NC_011757.1 KEGG: mex:Mext_0864 hypothetical protein; hypothetical protein 842038 7115817 Mchl_0824 Methylobacterium extorquens CM4 hypothetical protein YP_002419670.1 841577 D 440085 CDS YP_002419671.1 218528855 7115818 842044..843063 1 NC_011757.1 PFAM: von Willebrand factor type A; KEGG: mex:Mext_0865 von Willebrand factor type A; von Willebrand factor type A 843063 7115818 Mchl_0825 Methylobacterium extorquens CM4 von Willebrand factor type A YP_002419671.1 842044 D 440085 CDS YP_002419672.1 218528856 7115819 843075..843998 1 NC_011757.1 PFAM: von Willebrand factor type A; KEGG: mex:Mext_0866 von Willebrand factor type A; von Willebrand factor type A 843998 7115819 Mchl_0826 Methylobacterium extorquens CM4 von Willebrand factor type A YP_002419672.1 843075 D 440085 CDS YP_002419673.1 218528857 7115820 843998..844936 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_2 repeat protein; KEGG: mex:Mext_0867 hypotheticalprotein; hypothetical protein 844936 7115820 Mchl_0827 Methylobacterium extorquens CM4 hypothetical protein YP_002419673.1 843998 D 440085 CDS YP_002419674.1 218528858 7115821 844936..846252 1 NC_011757.1 KEGG: mex:Mext_0868 hypothetical protein; hypothetical protein 846252 7115821 Mchl_0828 Methylobacterium extorquens CM4 hypothetical protein YP_002419674.1 844936 D 440085 CDS YP_002419675.1 218528859 7115822 846340..847434 1 NC_011757.1 KEGG: mex:Mext_0869 hypothetical protein; hypothetical protein 847434 7115822 Mchl_0829 Methylobacterium extorquens CM4 hypothetical protein YP_002419675.1 846340 D 440085 CDS YP_002419676.1 218528860 7115823 847526..848527 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_0870 hypothetical protein; hypothetical protein 848527 7115823 Mchl_0830 Methylobacterium extorquens CM4 hypothetical protein YP_002419676.1 847526 D 440085 CDS YP_002419677.1 218528861 7115824 complement(848538..848828) 1 NC_011757.1 KEGG: mex:Mext_0871 hypothetical protein; hypothetical protein 848828 7115824 Mchl_0831 Methylobacterium extorquens CM4 hypothetical protein YP_002419677.1 848538 R 440085 CDS YP_002419678.1 218528862 7115825 complement(849097..850152) 1 NC_011757.1 KEGG: mex:Mext_0872 hypothetical protein; hypothetical protein 850152 7115825 Mchl_0832 Methylobacterium extorquens CM4 hypothetical protein YP_002419678.1 849097 R 440085 CDS YP_002419679.1 218528863 7115826 complement(850398..850814) 1 NC_011757.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B; KEGG: mex:Mext_0873 methionine-R-sulfoxide reductase; methionine-R-sulfoxide reductase 850814 7115826 Mchl_0833 Methylobacterium extorquens CM4 methionine-R-sulfoxide reductase YP_002419679.1 850398 R 440085 CDS YP_002419680.1 218528864 7115827 complement(850918..852084) 1 NC_011757.1 PFAM: ribonuclease BN; KEGG: mex:Mext_0874 ribonuclease BN; ribonuclease BN 852084 7115827 Mchl_0834 Methylobacterium extorquens CM4 ribonuclease BN YP_002419680.1 850918 R 440085 CDS YP_002419681.1 218528865 7115828 complement(852217..853683) 1 NC_011757.1 KEGG: mex:Mext_0875 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 853683 7115828 Mchl_0835 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002419681.1 852217 R 440085 CDS YP_002419682.1 218528866 7115829 complement(853888..855420) 1 NC_011757.1 catalyzes the formation of malonyl-CoA from malonate and CoA; malonyl-CoA synthase 855420 7115829 Mchl_0836 Methylobacterium extorquens CM4 malonyl-CoA synthase YP_002419682.1 853888 R 440085 CDS YP_002419683.1 218528867 7115830 complement(855564..856004) 1 NC_011757.1 KEGG: mex:Mext_0877 hypothetical protein; hypothetical protein 856004 7115830 Mchl_0837 Methylobacterium extorquens CM4 hypothetical protein YP_002419683.1 855564 R 440085 CDS YP_002419684.1 218528868 7115831 856345..857238 1 NC_011757.1 PFAM: Collagen triple helix repeat; KEGG: mex:Mext_0878 triple helix repeat-containing collagen; collagen 857238 7115831 Mchl_0838 Methylobacterium extorquens CM4 collagen YP_002419684.1 856345 D 440085 CDS YP_002419685.1 218528869 7115832 complement(857251..858474) 1 NC_011757.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; KEGG: mex:Mext_0879 hypothetical protein; hypothetical protein 858474 7115832 Mchl_0839 Methylobacterium extorquens CM4 hypothetical protein YP_002419685.1 857251 R 440085 CDS YP_002419686.1 218528870 7115833 858789..859814 1 NC_011757.1 PFAM: integral membrane protein TerC; KEGG: mex:Mext_0880 integral membrane protein TerC; integral membrane protein TerC 859814 7115833 Mchl_0840 Methylobacterium extorquens CM4 integral membrane protein TerC YP_002419686.1 858789 D 440085 CDS YP_002419687.1 218528871 7115834 859956..860258 1 NC_011757.1 KEGG: mex:Mext_0881 hypothetical protein; hypothetical protein 860258 7115834 Mchl_0841 Methylobacterium extorquens CM4 hypothetical protein YP_002419687.1 859956 D 440085 CDS YP_002419688.1 218528872 7115835 complement(860335..860913) 1 NC_011757.1 TIGRFAM: intracellular protease PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_0882 PfpI family intracellular peptidase; intracellular protease PfpI family 860913 7115835 Mchl_0842 Methylobacterium extorquens CM4 intracellular protease PfpI family YP_002419688.1 860335 R 440085 CDS YP_002419689.1 218528873 7115836 861097..861318 1 NC_011757.1 KEGG: mex:Mext_0883 hypothetical protein; hypothetical protein 861318 7115836 Mchl_0843 Methylobacterium extorquens CM4 hypothetical protein YP_002419689.1 861097 D 440085 CDS YP_002419690.1 218528874 7115837 861494..861928 1 NC_011757.1 KEGG: mex:Mext_0884 hypothetical protein; hypothetical protein 861928 7115837 Mchl_0844 Methylobacterium extorquens CM4 hypothetical protein YP_002419690.1 861494 D 440085 CDS YP_002419691.1 218528875 7115838 complement(861987..862376) 1 NC_011757.1 KEGG: mex:Mext_0885 hypothetical protein; hypothetical protein 862376 7115838 Mchl_0845 Methylobacterium extorquens CM4 hypothetical protein YP_002419691.1 861987 R 440085 CDS YP_002419692.1 218528876 7115842 862722..862931 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_0886 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 862931 7115842 Mchl_0846 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002419692.1 862722 D 440085 CDS YP_002419693.1 218528877 7115924 863139..863366 1 NC_011757.1 KEGG: mex:Mext_0887 hypothetical protein; hypothetical protein 863366 7115924 Mchl_0847 Methylobacterium extorquens CM4 hypothetical protein YP_002419693.1 863139 D 440085 CDS YP_002419694.1 218528878 7115925 complement(863536..863976) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_0888 hypothetical protein; hypothetical protein 863976 7115925 Mchl_0848 Methylobacterium extorquens CM4 hypothetical protein YP_002419694.1 863536 R 440085 CDS YP_002419695.1 218528879 7115926 complement(864080..865279) 1 NC_011757.1 KEGG: mex:Mext_0889 hypothetical protein; hypothetical protein 865279 7115926 Mchl_0849 Methylobacterium extorquens CM4 hypothetical protein YP_002419695.1 864080 R 440085 CDS YP_002419696.1 218528880 7115927 865448..866653 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0890 major facilitator transporter; major facilitator superfamily protein 866653 7115927 Mchl_0850 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419696.1 865448 D 440085 CDS YP_002419697.1 218528881 7115928 866899..868044 1 NC_011757.1 PFAM: protein of unknown function DUF140; KEGG: mex:Mext_0891 hypothetical protein; hypothetical protein 868044 7115928 Mchl_0851 Methylobacterium extorquens CM4 hypothetical protein YP_002419697.1 866899 D 440085 CDS YP_002419698.1 218528882 7115929 868079..868915 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_0892 ABC transporter; ABC transporter 868915 7115929 Mchl_0852 Methylobacterium extorquens CM4 ABC transporter YP_002419698.1 868079 D 440085 CDS YP_002419699.1 218528883 7115930 868987..870069 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_0893 hypothetical protein; hypothetical protein 870069 7115930 Mchl_0853 Methylobacterium extorquens CM4 hypothetical protein YP_002419699.1 868987 D 440085 CDS YP_002419700.1 218528884 7115931 870190..870813 1 NC_011757.1 PFAM: protein of unknown function DUF330; KEGG: mex:Mext_0894 hypothetical protein; hypothetical protein 870813 7115931 Mchl_0854 Methylobacterium extorquens CM4 hypothetical protein YP_002419700.1 870190 D 440085 CDS YP_002419701.1 218528885 7115932 complement(870857..871675) 1 NC_011757.1 PFAM: inositol monophosphatase; KEGG: mex:Mext_0895 inositol monophosphatase; inositol monophosphatase 871675 7115932 Mchl_0855 Methylobacterium extorquens CM4 inositol monophosphatase YP_002419701.1 870857 R 440085 CDS YP_002419702.1 218528886 7115933 872040..872540 1 NC_011757.1 KEGG: mex:Mext_0896 hypothetical protein; hypothetical protein 872540 7115933 Mchl_0856 Methylobacterium extorquens CM4 hypothetical protein YP_002419702.1 872040 D 440085 CDS YP_002419703.1 218528887 7115934 complement(872893..873843) 1 NC_011757.1 TIGRFAM: 4-hydroxybenzoate polyprenyl transferase; PFAM: UbiA prenyltransferase; KEGG: mex:Mext_0897 4-hydroxybenzoate polyprenyl transferase; 4-hydroxybenzoate polyprenyl transferase 873843 7115934 Mchl_0857 Methylobacterium extorquens CM4 4-hydroxybenzoate polyprenyl transferase YP_002419703.1 872893 R 440085 CDS YP_002419704.1 218528888 7115935 complement(873880..874482) 1 NC_011757.1 KEGG: mex:Mext_0898 signal peptide; signal peptide 874482 7115935 Mchl_0858 Methylobacterium extorquens CM4 signal peptide YP_002419704.1 873880 R 440085 CDS YP_002419705.1 218528889 7115936 874790..875542 1 NC_011757.1 PFAM: protein of unknown function DUF558; KEGG: mex:Mext_0899 hypothetical protein; hypothetical protein 875542 7115936 Mchl_0859 Methylobacterium extorquens CM4 hypothetical protein YP_002419705.1 874790 D 440085 CDS YP_002419706.1 218528890 7115937 875572..876555 1 NC_011757.1 PFAM: asparaginase/glutaminase; KEGG: mex:Mext_0900 asparaginase/glutaminase; asparaginase/glutaminase 876555 7115937 Mchl_0860 Methylobacterium extorquens CM4 asparaginase/glutaminase YP_002419706.1 875572 D 440085 CDS YP_002419707.1 218528891 7115938 876742..878112 1 NC_011757.1 KEGG: mex:Mext_0901 glutamate--cysteine ligase; TIGRFAM: glutamate/cysteine ligase; PFAM: glutamate--cysteine ligase; glutamate/cysteine ligase 878112 7115938 Mchl_0861 Methylobacterium extorquens CM4 glutamate/cysteine ligase YP_002419707.1 876742 D 440085 CDS YP_002419708.1 218528892 7115939 878224..878634 1 NC_011757.1 KEGG: mex:Mext_0902 hypothetical protein; hypothetical protein 878634 7115939 Mchl_0862 Methylobacterium extorquens CM4 hypothetical protein YP_002419708.1 878224 D 440085 CDS YP_002419709.1 218528893 7115940 878714..878980 1 NC_011757.1 PFAM: SirA family protein; KEGG: mex:Mext_0903 SirA family protein; SirA family protein 878980 7115940 Mchl_0863 Methylobacterium extorquens CM4 SirA family protein YP_002419709.1 878714 D 440085 CDS YP_002419710.1 218528894 7115941 879020..879586 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_0904 NUDIX hydrolase; NUDIX hydrolase 879586 7115941 Mchl_0864 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002419710.1 879020 D 440085 CDS YP_002419711.1 218528895 7115942 879684..879818 1 NC_011757.1 KEGG: mpo:Mpop_0833 hypothetical protein; hypothetical protein 879818 7115942 Mchl_0865 Methylobacterium extorquens CM4 hypothetical protein YP_002419711.1 879684 D 440085 CDS YP_002419712.1 218528896 7115943 880043..880441 1 NC_011757.1 KEGG: mex:Mext_0905 hypothetical protein; hypothetical protein 880441 7115943 Mchl_0866 Methylobacterium extorquens CM4 hypothetical protein YP_002419712.1 880043 D 440085 CDS YP_002419713.1 218528897 7115944 complement(880592..881032) 1 NC_011757.1 KEGG: mex:Mext_0906 hypothetical protein; hypothetical protein 881032 7115944 Mchl_0867 Methylobacterium extorquens CM4 hypothetical protein YP_002419713.1 880592 R 440085 CDS YP_002419714.1 218528898 7115945 complement(881278..881970) 1 NC_011757.1 KEGG: mex:Mext_0907 transmembrane signal peptide protein; transmembrane signal peptide protein 881970 7115945 Mchl_0868 Methylobacterium extorquens CM4 transmembrane signal peptide protein YP_002419714.1 881278 R 440085 CDS YP_002419715.1 218528899 7115946 complement(881967..882179) 1 NC_011757.1 PFAM: protein of unknown function DUF1289; KEGG: mex:Mext_0908 hypothetical protein; hypothetical protein 882179 7115946 Mchl_0869 Methylobacterium extorquens CM4 hypothetical protein YP_002419715.1 881967 R 440085 CDS YP_002419716.1 218528900 7115947 complement(882440..883117) 1 NC_011757.1 KEGG: mex:Mext_0909 hypothetical protein; hypothetical protein 883117 7115947 Mchl_0870 Methylobacterium extorquens CM4 hypothetical protein YP_002419716.1 882440 R 440085 CDS YP_002419717.1 218528901 7115948 complement(883132..883959) 1 NC_011757.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: mex:Mext_0910 cobalamin 5'-phosphate synthase; cobalamin 5'-phosphate synthase 883959 7115948 Mchl_0871 Methylobacterium extorquens CM4 cobalamin 5'-phosphate synthase YP_002419717.1 883132 R 440085 CDS YP_002419718.1 218528902 7115949 884127..885164 1 NC_011757.1 KEGG: mex:Mext_0911 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase 885164 7115949 Mchl_0872 Methylobacterium extorquens CM4 nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase YP_002419718.1 884127 D 440085 CDS YP_002419719.1 218528903 7115950 complement(885171..886712) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_0912 ATPase domain-containing protein; histidine kinase 886712 7115950 Mchl_0873 Methylobacterium extorquens CM4 histidine kinase YP_002419719.1 885171 R 440085 CDS YP_002419720.1 218528904 7115951 887055..887510 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_0913 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 887510 7115951 Mchl_0874 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002419720.1 887055 D 440085 CDS YP_002419721.1 218528905 7115952 887546..889741 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_0914 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 889741 7115952 Mchl_0875 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002419721.1 887546 D 440085 CDS YP_002419722.1 218528906 7115953 889922..893320 1 NC_011757.1 KEGG: mex:Mext_0915 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 893320 7115953 Mchl_0876 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002419722.1 889922 D 440085 CDS YP_002419723.1 218528907 7115954 complement(893409..894644) 1 NC_011757.1 PFAM: amidase; KEGG: mex:Mext_0916 amidase; amidase 894644 7115954 Mchl_0877 Methylobacterium extorquens CM4 amidase YP_002419723.1 893409 R 440085 CDS YP_002419724.1 218528908 7115955 894758..895747 1 NC_011757.1 PFAM: Extensin family protein; KEGG: mex:Mext_0917 extensin family protein; Extensin family protein 895747 7115955 Mchl_0878 Methylobacterium extorquens CM4 Extensin family protein YP_002419724.1 894758 D 440085 CDS YP_002419725.1 218528909 7115956 895928..896395 1 NC_011757.1 KEGG: mex:Mext_0918 hypothetical protein; hypothetical protein 896395 7115956 Mchl_0879 Methylobacterium extorquens CM4 hypothetical protein YP_002419725.1 895928 D 440085 CDS YP_002419726.1 218528910 7115957 896495..897169 1 NC_011757.1 PFAM: ribonuclease T2; KEGG: mex:Mext_0919 ribonuclease T2; ribonuclease T2 897169 7115957 Mchl_0880 Methylobacterium extorquens CM4 ribonuclease T2 YP_002419726.1 896495 D 440085 CDS YP_002419727.1 218528911 7115958 897223..898071 1 NC_011757.1 PFAM: protein of unknown function DUF519; KEGG: mex:Mext_0920 hypothetical protein; hypothetical protein 898071 7115958 Mchl_0881 Methylobacterium extorquens CM4 hypothetical protein YP_002419727.1 897223 D 440085 CDS YP_002419728.1 218528912 7115959 complement(898088..898357) 1 NC_011757.1 KEGG: mex:Mext_0921 hypothetical protein; hypothetical protein 898357 7115959 Mchl_0882 Methylobacterium extorquens CM4 hypothetical protein YP_002419728.1 898088 R 440085 CDS YP_002419729.1 218528913 7115960 complement(898372..898605) 1 NC_011757.1 KEGG: mex:Mext_0922 hypothetical protein; hypothetical protein 898605 7115960 Mchl_0883 Methylobacterium extorquens CM4 hypothetical protein YP_002419729.1 898372 R 440085 CDS YP_002419730.1 218528914 7115961 complement(898708..900141) 1 NC_011757.1 PFAM: FAD linked oxidase; KEGG: mex:Mext_0923 FAD linked oxidase domain-containing protein; FAD linked oxidase 900141 7115961 Mchl_0884 Methylobacterium extorquens CM4 FAD linked oxidase YP_002419730.1 898708 R 440085 CDS YP_002419731.1 218528915 7115962 900457..900819 1 NC_011757.1 PFAM: cytochrome C class I; KEGG: mex:Mext_0924 cytochrome c class I; cytochrome C class I 900819 7115962 Mchl_0885 Methylobacterium extorquens CM4 cytochrome C class I YP_002419731.1 900457 D 440085 CDS YP_002419732.1 218528916 7115963 complement(900916..901401) 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_0925 regulatory protein MarR; MarR family transcriptional regulator 901401 7115963 Mchl_0886 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002419732.1 900916 R 440085 CDS YP_002419733.1 218528917 7115964 complement(901947..902552) 1 NC_011757.1 KEGG: mex:Mext_0926 hypothetical protein; hypothetical protein 902552 7115964 Mchl_0887 Methylobacterium extorquens CM4 hypothetical protein YP_002419733.1 901947 R 440085 CDS YP_002419734.1 218528918 7115965 complement(902549..903280) 1 NC_011757.1 PFAM: protein of unknown function DUF1214; KEGG: mex:Mext_0927 hypothetical protein; hypothetical protein 903280 7115965 Mchl_0888 Methylobacterium extorquens CM4 hypothetical protein YP_002419734.1 902549 R 440085 CDS YP_002419735.1 218528919 7115966 complement(903291..905588) 1 NC_011757.1 KEGG: mex:Mext_0928 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; penicillin-binding protein, 1A family 905588 7115966 Mchl_0889 Methylobacterium extorquens CM4 penicillin-binding protein, 1A family YP_002419735.1 903291 R 440085 CDS YP_002419736.1 218528920 7115967 905899..906363 1 NC_011757.1 PFAM: protein of unknown function UPF0153; KEGG: mex:Mext_0929 hypothetical protein; hypothetical protein 906363 7115967 Mchl_0890 Methylobacterium extorquens CM4 hypothetical protein YP_002419736.1 905899 D 440085 CDS YP_002419737.1 218528921 7115968 complement(906373..907029) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_0930 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 907029 7115968 Mchl_0891 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002419737.1 906373 R 440085 CDS YP_002419738.1 218528922 7115969 907307..907858 1 NC_011757.1 PFAM: TadE family protein; KEGG: mex:Mext_0931 TadE family protein; TadE family protein 907858 7115969 Mchl_0892 Methylobacterium extorquens CM4 TadE family protein YP_002419738.1 907307 D 440085 CDS YP_002419739.1 218528923 7115970 907858..908691 1 NC_011757.1 KEGG: mex:Mext_0932 hypothetical protein; hypothetical protein 908691 7115970 Mchl_0893 Methylobacterium extorquens CM4 hypothetical protein YP_002419739.1 907858 D 440085 CDS YP_002419740.1 218528924 7115971 908676..910109 1 NC_011757.1 KEGG: mex:Mext_0933 hypothetical protein; hypothetical protein 910109 7115971 Mchl_0894 Methylobacterium extorquens CM4 hypothetical protein YP_002419740.1 908676 D 440085 CDS YP_002419741.1 218528925 7115972 910368..911582 1 NC_011757.1 PFAM: AFG1-family ATPase; KEGG: mex:Mext_0934 AFG1 family ATPase; AFG1-family ATPase 911582 7115972 Mchl_0895 Methylobacterium extorquens CM4 AFG1-family ATPase YP_002419741.1 910368 D 440085 CDS YP_002419742.1 218528926 7115973 complement(911579..912205) 1 NC_011757.1 TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); KEGG: mex:Mext_0935 DNA-3-methyladenine glycosylase; DNA-3-methyladenine glycosylase 912205 7115973 Mchl_0896 Methylobacterium extorquens CM4 DNA-3-methyladenine glycosylase YP_002419742.1 911579 R 440085 CDS YP_002419743.1 218528927 7115974 complement(912278..912964) 1 NC_011757.1 PFAM: ribonuclease H; KEGG: mex:Mext_0936 ribonuclease H; ribonuclease H 912964 7115974 Mchl_0897 Methylobacterium extorquens CM4 ribonuclease H YP_002419743.1 912278 R 440085 CDS YP_002419744.1 218528928 7115975 complement(913017..913802) 1 NC_011757.1 KEGG: mex:Mext_0937 hypothetical protein; hypothetical protein 913802 7115975 Mchl_0898 Methylobacterium extorquens CM4 hypothetical protein YP_002419744.1 913017 R 440085 CDS YP_002419745.1 218528929 7115976 complement(913799..914050) 1 NC_011757.1 KEGG: mpo:Mpop_0874 hypothetical protein; hypothetical protein 914050 7115976 Mchl_0899 Methylobacterium extorquens CM4 hypothetical protein YP_002419745.1 913799 R 440085 CDS YP_002419746.1 218528930 7115977 914515..914823 1 NC_011757.1 KEGG: mex:Mext_0938 hypothetical protein; hypothetical protein 914823 7115977 Mchl_0900 Methylobacterium extorquens CM4 hypothetical protein YP_002419746.1 914515 D 440085 CDS YP_002419747.1 218528931 7115978 915124..916086 1 NC_011757.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 916086 7115978 Mchl_0901 Methylobacterium extorquens CM4 glutathione synthetase YP_002419747.1 915124 D 440085 CDS YP_002419748.1 218528932 7115979 complement(916145..916300) 1 NC_011757.1 KEGG: mpo:Mpop_0877 hypothetical protein; hypothetical protein 916300 7115979 Mchl_0902 Methylobacterium extorquens CM4 hypothetical protein YP_002419748.1 916145 R 440085 CDS YP_002419749.1 218528933 7115980 complement(916958..918535) 1 NC_011757.1 PFAM: sodium/hydrogen exchanger; KEGG: mex:Mext_0940 sodium/hydrogen exchanger; sodium/hydrogen exchanger 918535 7115980 Mchl_0903 Methylobacterium extorquens CM4 sodium/hydrogen exchanger YP_002419749.1 916958 R 440085 CDS YP_002419750.1 218528934 7115981 complement(918633..919385) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD 919385 7115981 Mchl_0904 Methylobacterium extorquens CM4 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_002419750.1 918633 R 440085 CDS YP_002419751.1 218528935 7115982 complement(919382..920107) 1 NC_011757.1 PFAM: heat shock protein DnaJ domain protein; protein of unknown function DUF1332; KEGG: mex:Mext_0942 heat shock protein DnaJ domain-containing protein; hypothetical protein 920107 7115982 Mchl_0905 Methylobacterium extorquens CM4 hypothetical protein YP_002419751.1 919382 R 440085 CDS YP_002419752.1 218528936 7115983 complement(920309..921400) 1 NC_011757.1 KEGG: mpo:Mpop_0881 hypothetical protein; hypothetical protein 921400 7115983 Mchl_0906 Methylobacterium extorquens CM4 hypothetical protein YP_002419752.1 920309 R 440085 CDS YP_002419753.1 218528937 7115984 921531..921683 1 NC_011757.1 KEGG: mpo:Mpop_0883 hypothetical protein; hypothetical protein 921683 7115984 Mchl_0907 Methylobacterium extorquens CM4 hypothetical protein YP_002419753.1 921531 D 440085 CDS YP_002419754.1 218528938 7115985 922010..922210 1 NC_011757.1 KEGG: mpo:Mpop_0884 hypothetical protein; hypothetical protein 922210 7115985 Mchl_0908 Methylobacterium extorquens CM4 hypothetical protein YP_002419754.1 922010 D 440085 CDS YP_002419755.1 218528939 7115986 922584..923606 1 NC_011757.1 PFAM: dihydrouridine synthase; KEGG: mex:Mext_0946 tRNA-dihydrouridine synthase A; tRNA-dihydrouridine synthase A 923606 7115986 Mchl_0909 Methylobacterium extorquens CM4 tRNA-dihydrouridine synthase A YP_002419755.1 922584 D 440085 CDS YP_002419756.1 218528940 7115987 complement(923646..925790) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_0947 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 925790 7115987 Mchl_0910 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002419756.1 923646 R 440085 CDS YP_002419757.1 218528941 7115988 complement(926119..926571) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_0948 response regulator receiver; response regulator receiver protein 926571 7115988 Mchl_0911 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419757.1 926119 R 440085 CDS YP_002419758.1 218528942 7115989 complement(926633..927100) 1 NC_011757.1 PFAM: BLUF domain protein; KEGG: mex:Mext_0949 BLUF domain-containing protein; BLUF domain-containing protein 927100 7115989 Mchl_0912 Methylobacterium extorquens CM4 BLUF domain-containing protein YP_002419758.1 926633 R 440085 CDS YP_002419759.1 218528943 7115990 927334..928716 1 NC_011757.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: mex:Mext_0950 hypothetical protein; hypothetical protein 928716 7115990 Mchl_0913 Methylobacterium extorquens CM4 hypothetical protein YP_002419759.1 927334 D 440085 CDS YP_002419760.1 218528944 7115991 928743..930641 1 NC_011757.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: mex:Mext_0951 flagellar hook-associated protein FlgK; flagellar hook-associated protein FlgK 930641 7115991 Mchl_0914 Methylobacterium extorquens CM4 flagellar hook-associated protein FlgK YP_002419760.1 928743 D 440085 CDS YP_002419761.1 218528945 7115992 930656..932449 1 NC_011757.1 KEGG: mex:Mext_0952 hypothetical protein; hypothetical protein 932449 7115992 Mchl_0915 Methylobacterium extorquens CM4 hypothetical protein YP_002419761.1 930656 D 440085 CDS YP_002419762.1 218528946 7115993 complement(932549..933844) 1 NC_011757.1 KEGG: mex:Mext_0953 hypothetical protein; hypothetical protein 933844 7115993 Mchl_0916 Methylobacterium extorquens CM4 hypothetical protein YP_002419762.1 932549 R 440085 CDS YP_002419763.1 218528947 7115994 complement(934393..935283) 1 NC_011757.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: mex:Mext_0954 protein-(glutamine-N5) methyltransferase, release factor-specific; HemK family modification methylase 935283 7115994 Mchl_0917 Methylobacterium extorquens CM4 HemK family modification methylase YP_002419763.1 934393 R 440085 CDS YP_002419764.1 218528948 7115995 complement(935298..936383) 1 NC_011757.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 936383 prfA 7115995 prfA Methylobacterium extorquens CM4 peptide chain release factor 1 YP_002419764.1 935298 R 440085 CDS YP_002419765.1 218528949 7115996 complement(936578..937237) 1 NC_011757.1 KEGG: mex:Mext_0956 hypothetical protein; hypothetical protein 937237 7115996 Mchl_0919 Methylobacterium extorquens CM4 hypothetical protein YP_002419765.1 936578 R 440085 CDS YP_002419766.1 218528950 7115997 complement(937283..939544) 1 NC_011757.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: mex:Mext_0957 phosphoenolpyruvate-protein phosphotransferase; PTSINtr with GAF domain, PtsP 939544 7115997 Mchl_0920 Methylobacterium extorquens CM4 PTSINtr with GAF domain, PtsP YP_002419766.1 937283 R 440085 CDS YP_002419767.1 218528951 7115998 complement(939616..940851) 1 NC_011757.1 KEGG: mex:Mext_0958 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; aspartate kinase 940851 7115998 Mchl_0921 Methylobacterium extorquens CM4 aspartate kinase YP_002419767.1 939616 R 440085 CDS YP_002419768.1 218528952 7115999 941219..941956 1 NC_011757.1 KEGG: mex:Mext_0959 ubiquinone biosynthesis O-methyltransferase; TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12; ubiquinone biosynthesis O-methyltransferase 941956 7115999 Mchl_0922 Methylobacterium extorquens CM4 ubiquinone biosynthesis O-methyltransferase YP_002419768.1 941219 D 440085 CDS YP_002419769.1 218528953 7116000 942032..942604 1 NC_011757.1 PFAM: PEBP family protein; KEGG: mex:Mext_0960 PEBP family protein; PEBP family protein 942604 7116000 Mchl_0923 Methylobacterium extorquens CM4 PEBP family protein YP_002419769.1 942032 D 440085 CDS YP_002419770.1 218528954 7116001 942741..943721 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_0961 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 943721 7116001 Mchl_0924 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002419770.1 942741 D 440085 CDS YP_002419771.1 218528955 7116003 complement(943946..944515) 1 NC_011757.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 944515 ruvC 7116003 ruvC Methylobacterium extorquens CM4 Holliday junction resolvase YP_002419771.1 943946 R 440085 CDS YP_002419772.1 218528956 7116004 complement(944605..945246) 1 NC_011757.1 PFAM: YceI family protein; KEGG: mex:Mext_0963 YceI family protein; YceI family protein 945246 7116004 Mchl_0927 Methylobacterium extorquens CM4 YceI family protein YP_002419772.1 944605 R 440085 CDS YP_002419773.1 218528957 7114695 945333..945959 1 NC_011757.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 945959 ruvA 7114695 ruvA Methylobacterium extorquens CM4 Holliday junction DNA helicase RuvA YP_002419773.1 945333 D 440085 CDS YP_002419774.1 218528958 7114696 complement(945976..946272) 1 NC_011757.1 KEGG: mex:Mext_0965 hypothetical protein; hypothetical protein 946272 7114696 Mchl_0929 Methylobacterium extorquens CM4 hypothetical protein YP_002419774.1 945976 R 440085 CDS YP_002419775.1 218528959 7114697 946350..946730 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mpo:Mpop_0906 response regulator receiver protein; response regulator receiver protein 946730 7114697 Mchl_0930 Methylobacterium extorquens CM4 response regulator receiver protein YP_002419775.1 946350 D 440085 CDS YP_002419776.1 218528960 7114698 946786..948159 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: mex:Mext_0967 diguanylate cyclase; response regulator receiver modulated diguanylate cyclase 948159 7114698 Mchl_0931 Methylobacterium extorquens CM4 response regulator receiver modulated diguanylate cyclase YP_002419776.1 946786 D 440085 CDS YP_002419777.1 218528961 7114699 complement(948177..948650) 1 NC_011757.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mex:Mext_0968 rrf2 family transcriptional regulator; BadM/Rrf2 family transcriptional regulator 948650 7114699 Mchl_0932 Methylobacterium extorquens CM4 BadM/Rrf2 family transcriptional regulator YP_002419777.1 948177 R 440085 CDS YP_002419778.1 218528962 7114700 948745..949989 1 NC_011757.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 949989 7114700 Mchl_0933 Methylobacterium extorquens CM4 nitric oxide dioxygenase YP_002419778.1 948745 D 440085 CDS YP_002419779.1 218528963 7114701 complement(950017..950181) 1 NC_011757.1 KEGG: mex:Mext_0970 hypothetical protein; hypothetical protein 950181 7114701 Mchl_0934 Methylobacterium extorquens CM4 hypothetical protein YP_002419779.1 950017 R 440085 CDS YP_002419780.1 218528964 7114702 complement(950273..950599) 1 NC_011757.1 KEGG: mex:Mext_0971 hypothetical protein; hypothetical protein 950599 7114702 Mchl_0935 Methylobacterium extorquens CM4 hypothetical protein YP_002419780.1 950273 R 440085 CDS YP_002419781.1 218528965 7114703 complement(950589..950993) 1 NC_011757.1 KEGG: mex:Mext_0972 hypothetical protein; hypothetical protein 950993 7114703 Mchl_0936 Methylobacterium extorquens CM4 hypothetical protein YP_002419781.1 950589 R 440085 CDS YP_002419782.1 218528966 7114704 complement(951085..952065) 1 NC_011757.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: mex:Mext_0973 cysteine synthase A; cysteine synthase A 952065 7114704 Mchl_0937 Methylobacterium extorquens CM4 cysteine synthase A YP_002419782.1 951085 R 440085 CDS YP_002419783.1 218528967 7114705 complement(952422..952598) 1 NC_011757.1 KEGG: mex:Mext_0974 hypothetical protein; hypothetical protein 952598 7114705 Mchl_0938 Methylobacterium extorquens CM4 hypothetical protein YP_002419783.1 952422 R 440085 CDS YP_002419784.1 218528968 7114706 complement(952777..953280) 1 NC_011757.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: mex:Mext_0975 protein of unknown function DUF306 MetA and HslJ; hypothetical protein 953280 7114706 Mchl_0939 Methylobacterium extorquens CM4 hypothetical protein YP_002419784.1 952777 R 440085 CDS YP_002419785.1 218528969 7114707 953737..954015 1 NC_011757.1 KEGG: mex:Mext_0976 hypothetical protein; hypothetical protein 954015 7114707 Mchl_0940 Methylobacterium extorquens CM4 hypothetical protein YP_002419785.1 953737 D 440085 CDS YP_002419786.1 218528970 7114708 complement(954025..955266) 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_0977 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 955266 7114708 Mchl_0941 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002419786.1 954025 R 440085 CDS YP_002419787.1 218528971 7114709 complement(955263..956252) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_0978 LysR substrate-binding; LysR family transcriptional regulator 956252 7114709 Mchl_0942 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002419787.1 955263 R 440085 CDS YP_002419788.1 218528972 7114710 956461..957507 1 NC_011757.1 PFAM: inositol phosphatase/fructose-16-bisphosphatase; KEGG: mex:Mext_0979 inositol phosphatase/fructose-16-bisphosphatase; inositol phosphatase/fructose-16-bisphosphatase 957507 7114710 Mchl_0943 Methylobacterium extorquens CM4 inositol phosphatase/fructose-16-bisphosphatase YP_002419788.1 956461 D 440085 CDS YP_002419789.1 218528973 7114711 957655..958515 1 NC_011757.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: mex:Mext_0980 phosphoribulokinase; phosphoribulokinase 958515 7114711 Mchl_0944 Methylobacterium extorquens CM4 phosphoribulokinase YP_002419789.1 957655 D 440085 CDS YP_002419790.1 218528974 7114712 complement(958587..959546) 1 NC_011757.1 KEGG: mex:Mext_0981 hypothetical protein; hypothetical protein 959546 7114712 Mchl_0945 Methylobacterium extorquens CM4 hypothetical protein YP_002419790.1 958587 R 440085 CDS YP_002419791.1 218528975 7114713 complement(959660..960406) 1 NC_011757.1 PFAM: protein of unknown function DUF28; KEGG: mex:Mext_0982 hypothetical protein; hypothetical protein 960406 7114713 Mchl_0946 Methylobacterium extorquens CM4 hypothetical protein YP_002419791.1 959660 R 440085 CDS YP_002419792.1 218528976 7114714 complement(960894..961706) 1 NC_011757.1 KEGG: mex:Mext_0984 beta-lactamase-like protein; beta-lactamase-like protein 961706 7114714 Mchl_0947 Methylobacterium extorquens CM4 beta-lactamase-like protein YP_002419792.1 960894 R 440085 CDS YP_002419793.1 218528977 7114715 962138..962452 1 NC_011757.1 KEGG: mex:Mext_0985 hypothetical protein; hypothetical protein 962452 7114715 Mchl_0948 Methylobacterium extorquens CM4 hypothetical protein YP_002419793.1 962138 D 440085 CDS YP_002419794.1 218528978 7114716 complement(962476..963618) 1 NC_011757.1 KEGG: mex:Mext_0986 hypothetical protein; hypothetical protein 963618 7114716 Mchl_0949 Methylobacterium extorquens CM4 hypothetical protein YP_002419794.1 962476 R 440085 CDS YP_002419795.1 218528979 7114717 complement(963618..964994) 1 NC_011757.1 PFAM: polysaccharide biosynthesis protein; KEGG: mex:Mext_0987 polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 964994 7114717 Mchl_0950 Methylobacterium extorquens CM4 polysaccharide biosynthesis protein YP_002419795.1 963618 R 440085 CDS YP_002419796.1 218528980 7114718 complement(965113..966096) 1 NC_011757.1 KEGG: mex:Mext_0988 hypothetical protein; hypothetical protein 966096 7114718 Mchl_0951 Methylobacterium extorquens CM4 hypothetical protein YP_002419796.1 965113 R 440085 CDS YP_002419797.1 218528981 7114719 complement(966015..967154) 1 NC_011757.1 KEGG: mex:Mext_0989 OpgC protein; OpgC protein 967154 7114719 Mchl_0952 Methylobacterium extorquens CM4 OpgC protein YP_002419797.1 966015 R 440085 CDS YP_002419798.1 218528982 7114720 complement(967344..968105) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: mex:Mext_0990 HAD family hydrolase; HAD-superfamily hydrolase 968105 7114720 Mchl_0953 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002419798.1 967344 R 440085 CDS YP_002419799.1 218528983 7114721 complement(968099..968782) 1 NC_011757.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: mex:Mext_0991 ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 968782 7114721 Mchl_0954 Methylobacterium extorquens CM4 ribulose-phosphate 3-epimerase YP_002419799.1 968099 R 440085 CDS YP_002419800.1 218528984 7114722 complement(968972..969586) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mpo:Mpop_0933 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 969586 7114722 Mchl_0955 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002419800.1 968972 R 440085 CDS YP_002419801.1 218528985 7114723 complement(969586..971931) 1 NC_011757.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: mex:Mext_0993 ornithine decarboxylase; ornithine decarboxylase 971931 7114723 Mchl_0956 Methylobacterium extorquens CM4 ornithine decarboxylase YP_002419801.1 969586 R 440085 CDS YP_002419802.1 218528986 7114724 complement(972016..972336) 1 NC_011757.1 TIGRFAM: TonB family protein; KEGG: mex:Mext_0994 TonB family protein; TonB family protein 972336 7114724 Mchl_0957 Methylobacterium extorquens CM4 TonB family protein YP_002419802.1 972016 R 440085 CDS YP_002419803.1 218528987 7114725 complement(972646..973203) 1 NC_011757.1 TIGRFAM: molybdenum cofactor synthesis protein; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: mex:Mext_0995 molybdenum cofactor biosynthesis protein B; molybdenum cofactor biosynthesis protein B 973203 7114725 Mchl_0958 Methylobacterium extorquens CM4 molybdenum cofactor biosynthesis protein B YP_002419803.1 972646 R 440085 CDS YP_002419804.1 218528988 7114726 973366..974673 1 NC_011757.1 TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; adenylosuccinate lyase 974673 7114726 Mchl_0959 Methylobacterium extorquens CM4 adenylosuccinate lyase YP_002419804.1 973366 D 440085 CDS YP_002419805.1 218528989 7114727 974731..975588 1 NC_011757.1 PFAM: aminotransferase class IV; KEGG: mex:Mext_0997 aminotransferase class IV; class IV aminotransferase 975588 7114727 Mchl_0960 Methylobacterium extorquens CM4 class IV aminotransferase YP_002419805.1 974731 D 440085 CDS YP_002419806.1 218528990 7114728 975661..975978 1 NC_011757.1 KEGG: mex:Mext_0998 hypothetical protein; hypothetical protein 975978 7114728 Mchl_0961 Methylobacterium extorquens CM4 hypothetical protein YP_002419806.1 975661 D 440085 CDS YP_002419807.1 218528991 7114729 976166..977458 1 NC_011757.1 PFAM: adenylosuccinate synthetase; KEGG: mex:Mext_0999 adenylosuccinate synthase; adenylosuccinate synthase 977458 7114729 Mchl_0962 Methylobacterium extorquens CM4 adenylosuccinate synthase YP_002419807.1 976166 D 440085 CDS YP_002419808.1 218528992 7114730 977500..978981 1 NC_011757.1 KEGG: mex:Mext_1000 hypothetical protein; hypothetical protein 978981 7114730 Mchl_0963 Methylobacterium extorquens CM4 hypothetical protein YP_002419808.1 977500 D 440085 CDS YP_002419809.1 218528993 7114731 complement(979137..980030) 1 NC_011757.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 980030 7114731 Mchl_0964 Methylobacterium extorquens CM4 RNA polymerase factor sigma-32 YP_002419809.1 979137 R 440085 CDS YP_002419810.1 218528994 7114732 complement(980295..982301) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_1002 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 982301 7114732 Mchl_0965 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002419810.1 980295 R 440085 CDS YP_002419811.1 218528995 7114733 982736..983002 1 NC_011757.1 KEGG: mex:Mext_1003 hypothetical protein; hypothetical protein 983002 7114733 Mchl_0966 Methylobacterium extorquens CM4 hypothetical protein YP_002419811.1 982736 D 440085 CDS YP_002419812.1 218528996 7114734 complement(983039..983488) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_1004 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 983488 7114734 Mchl_0967 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002419812.1 983039 R 440085 CDS YP_002419813.1 218528997 7114735 complement(983704..984735) 1 NC_011757.1 KEGG: mex:Mext_1005 RluA family pseudouridine synthase; TIGRFAM: pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; pseudouridine synthase 984735 7114735 Mchl_0968 Methylobacterium extorquens CM4 pseudouridine synthase YP_002419813.1 983704 R 440085 CDS YP_002419814.1 218528998 7114736 complement(984732..986012) 1 NC_011757.1 PFAM: integrase family protein; KEGG: nwi:Nwi_0275 phage integrase; integrase family protein 986012 7114736 Mchl_0969 Methylobacterium extorquens CM4 integrase family protein YP_002419814.1 984732 R 440085 CDS YP_002419815.1 218528999 7114738 complement(986560..987663) 1 NC_011757.1 PFAM: integrase family protein; KEGG: nwi:Nwi_0275 phage integrase; integrase family protein 987663 7114738 Mchl_0970 Methylobacterium extorquens CM4 integrase family protein YP_002419815.1 986560 R 440085 CDS YP_002419816.1 218529000 7114739 complement(987654..987893) 1 NC_011757.1 KEGG: dsh:Dshi_0989 hypothetical protein; hypothetical protein 987893 7114739 Mchl_0971 Methylobacterium extorquens CM4 hypothetical protein YP_002419816.1 987654 R 440085 CDS YP_002419817.1 218529001 7114740 complement(988282..988968) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: gbe:GbCGDNIH1_1593 transcriptional repressor; XRE family transcriptional regulator 988968 7114740 Mchl_0972 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419817.1 988282 R 440085 CDS YP_002419818.1 218529002 7114741 complement(988994..989695) 1 NC_011757.1 KEGG: LOC100075123; similar to splicing coactivator subunit SRm300; hypothetical protein 989695 7114741 Mchl_0973 Methylobacterium extorquens CM4 hypothetical protein YP_002419818.1 988994 R 440085 CDS YP_002419819.1 218529003 7114742 complement(989790..992003) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mrd:Mrad2831_4099 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 992003 7114742 Mchl_0974 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002419819.1 989790 R 440085 CDS YP_002419820.1 218529004 7114743 992294..993259 1 NC_011757.1 PFAM: esterase; KEGG: azc:AZC_3250 esterase; esterase 993259 7114743 Mchl_0975 Methylobacterium extorquens CM4 esterase YP_002419820.1 992294 D 440085 CDS YP_002419821.1 218529005 7114744 994164..994613 1 NC_011757.1 hypothetical protein 994613 7114744 Mchl_0976 Methylobacterium extorquens CM4 hypothetical protein YP_002419821.1 994164 D 440085 CDS YP_002419822.1 218529006 7114745 994821..995648 1 NC_011757.1 KEGG: mpo:Mpop_3836 hypothetical protein; hypothetical protein 995648 7114745 Mchl_0977 Methylobacterium extorquens CM4 hypothetical protein YP_002419822.1 994821 D 440085 CDS YP_002419823.1 218529007 7114747 998569..1000605 1 NC_011757.1 PFAM: Resolvase domain; Recombinase; KEGG: mpo:Mpop_3843 resolvase domain; Resolvase domain 1000605 7114747 Mchl_0979 Methylobacterium extorquens CM4 Resolvase domain YP_002419823.1 998569 D 440085 CDS YP_002419824.1 218529008 7114748 1001033..1003156 1 NC_011757.1 PFAM: Resolvase domain; KEGG: mpo:Mpop_3842 resolvase domain; Resolvase domain 1003156 7114748 Mchl_0980 Methylobacterium extorquens CM4 Resolvase domain YP_002419824.1 1001033 D 440085 CDS YP_002419825.1 218529009 7114749 1003882..1004619 1 NC_011757.1 hypothetical protein 1004619 7114749 Mchl_0981 Methylobacterium extorquens CM4 hypothetical protein YP_002419825.1 1003882 D 440085 CDS YP_002419826.1 218529010 7114750 complement(1004656..1005159) 1 NC_011757.1 KEGG: mrd:Mrad2831_5193 metallophosphoesterase; metallophosphoesterase 1005159 7114750 Mchl_0982 Methylobacterium extorquens CM4 metallophosphoesterase YP_002419826.1 1004656 R 440085 CDS YP_002419827.1 218529011 7114751 1005311..1005553 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: pde:Pden_3837 helix-turn-helix domain protein; XRE family transcriptional regulator 1005553 7114751 Mchl_0983 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419827.1 1005311 D 440085 CDS YP_002419828.1 218529012 7114752 1006388..1007266 1 NC_011757.1 KEGG: mpo:Mpop_3836 hypothetical protein; hypothetical protein 1007266 7114752 Mchl_0984 Methylobacterium extorquens CM4 hypothetical protein YP_002419828.1 1006388 D 440085 CDS YP_002419829.1 218529013 7114753 1007263..1009314 1 NC_011757.1 PFAM: peptidase M41; ATPase AAA central domain protein; SMART: ATPase AAA; KEGG: mpo:Mpop_3837 ATPase AAA central domain protein; ATPase AAA 1009314 7114753 Mchl_0985 Methylobacterium extorquens CM4 ATPase AAA YP_002419829.1 1007263 D 440085 CDS YP_002419830.1 218529014 7114754 1009452..1009814 1 NC_011757.1 KEGG: mpo:Mpop_3838 hypothetical protein; hypothetical protein 1009814 7114754 Mchl_0986 Methylobacterium extorquens CM4 hypothetical protein YP_002419830.1 1009452 D 440085 CDS YP_002419831.1 218529015 7114758 complement(1010977..1011327) 1 NC_011757.1 hypothetical protein 1011327 7114758 Mchl_0990 Methylobacterium extorquens CM4 hypothetical protein YP_002419831.1 1010977 R 440085 CDS YP_002419832.1 218529016 7114759 complement(1011978..1012403) 1 NC_011757.1 KEGG: art:Arth_0448 hypothetical protein; hypothetical protein 1012403 7114759 Mchl_0991 Methylobacterium extorquens CM4 hypothetical protein YP_002419832.1 1011978 R 440085 CDS YP_002419833.1 218529017 7114761 1013224..1013691 1 NC_011757.1 KEGG: mrd:Mrad2831_2532 hypothetical protein; hypothetical protein 1013691 7114761 Mchl_0993 Methylobacterium extorquens CM4 hypothetical protein YP_002419833.1 1013224 D 440085 CDS YP_002419834.1 218529018 7114762 1013778..1015529 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: met:M446_0182 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 1015529 7114762 Mchl_0994 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002419834.1 1013778 D 440085 CDS YP_002419835.1 218529019 7114763 1015542..1018688 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: met:M446_0181 CzcA family heavy metal efflux protein; CzcA family heavy metal efflux pump 1018688 7114763 Mchl_0995 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002419835.1 1015542 D 440085 CDS YP_002419836.1 218529020 7114764 1018722..1019087 1 NC_011757.1 KEGG: mrd:Mrad2831_2535 hypothetical protein; hypothetical protein 1019087 7114764 Mchl_0996 Methylobacterium extorquens CM4 hypothetical protein YP_002419836.1 1018722 D 440085 CDS YP_002419837.1 218529021 7114765 1019110..1019556 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: met:M446_0179 hypothetical protein; hypothetical protein 1019556 7114765 Mchl_0997 Methylobacterium extorquens CM4 hypothetical protein YP_002419837.1 1019110 D 440085 CDS YP_002419838.1 218529022 7114766 1019748..1020080 1 NC_011757.1 KEGG: mpo:Mpop_0107 hypothetical protein; hypothetical protein 1020080 7114766 Mchl_0998 Methylobacterium extorquens CM4 hypothetical protein YP_002419838.1 1019748 D 440085 CDS YP_002419839.1 218529023 7114767 1020104..1020337 1 NC_011757.1 KEGG: mpo:Mpop_4128 hypothetical protein; hypothetical protein 1020337 7114767 Mchl_0999 Methylobacterium extorquens CM4 hypothetical protein YP_002419839.1 1020104 D 440085 CDS YP_002419840.1 218529024 7114768 1020503..1022932 1 NC_011757.1 KEGG: met:M446_0177 heavy metal translocating P-type ATPase; TIGRFAM: ATPase P; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein; ATPase P 1022932 7114768 Mchl_1000 Methylobacterium extorquens CM4 ATPase P YP_002419840.1 1020503 D 440085 CDS YP_002419841.1 218529025 7114769 1023006..1023167 1 NC_011757.1 KEGG: mpo:Mpop_0104 hypothetical protein; hypothetical protein 1023167 7114769 Mchl_1001 Methylobacterium extorquens CM4 hypothetical protein YP_002419841.1 1023006 D 440085 CDS YP_002419842.1 218529026 7114770 1023243..1023719 1 NC_011757.1 PFAM: protein of unknown function DUF411; KEGG: mpo:Mpop_4113 protein of unknown function DUF411; hypothetical protein 1023719 7114770 Mchl_1002 Methylobacterium extorquens CM4 hypothetical protein YP_002419842.1 1023243 D 440085 CDS YP_002419843.1 218529027 7114772 1025638..1027707 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mrd:Mrad2831_4063 TonB-dependent receptor plug; TonB-dependent receptor plug 1027707 7114772 Mchl_1004 Methylobacterium extorquens CM4 TonB-dependent receptor plug YP_002419843.1 1025638 D 440085 CDS YP_002419844.1 218529028 7114773 complement(1027609..1027851) 1 NC_011757.1 hypothetical protein 1027851 7114773 Mchl_1005 Methylobacterium extorquens CM4 hypothetical protein YP_002419844.1 1027609 R 440085 CDS YP_002419845.1 218529029 7114774 complement(1028378..1028593) 1 NC_011757.1 KEGG: mpo:Mpop_4115 hypothetical protein; hypothetical protein 1028593 7114774 Mchl_1006 Methylobacterium extorquens CM4 hypothetical protein YP_002419845.1 1028378 R 440085 CDS YP_002419846.1 218529030 7114775 complement(1029161..1029463) 1 NC_011757.1 PFAM: protein of unknown function DUF156; KEGG: mpo:Mpop_2536 protein of unknown function DUF156; hypothetical protein 1029463 7114775 Mchl_1007 Methylobacterium extorquens CM4 hypothetical protein YP_002419846.1 1029161 R 440085 CDS YP_002419847.1 218529031 7114776 1029858..1030121 1 NC_011757.1 PFAM: Heavy metal transport/detoxification protein; KEGG: mpo:Mpop_2540 heavy metal transport/detoxification protein; Heavy metal transport/detoxification protein 1030121 7114776 Mchl_1008 Methylobacterium extorquens CM4 Heavy metal transport/detoxification protein YP_002419847.1 1029858 D 440085 CDS YP_002419848.1 218529032 7118512 1030420..1031712 1 NC_011757.1 KEGG: mpo:Mpop_2541 hypothetical protein; hypothetical protein 1031712 7118512 Mchl_1009 Methylobacterium extorquens CM4 hypothetical protein YP_002419848.1 1030420 D 440085 CDS YP_002419849.1 218529033 7118513 1032163..1033620 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mpo:Mpop_2542 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 1033620 7118513 Mchl_1010 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002419849.1 1032163 D 440085 CDS YP_002419850.1 218529034 7118514 complement(1033613..1033870) 1 NC_011757.1 hypothetical protein 1033870 7118514 Mchl_1011 Methylobacterium extorquens CM4 hypothetical protein YP_002419850.1 1033613 R 440085 CDS YP_002419851.1 218529035 7118515 complement(1033921..1034805) 1 NC_011757.1 KEGG: mpo:Mpop_2553 hypothetical protein; hypothetical protein 1034805 7118515 Mchl_1012 Methylobacterium extorquens CM4 hypothetical protein YP_002419851.1 1033921 R 440085 CDS YP_002419852.1 218529036 7118516 complement(1034898..1035746) 1 NC_011757.1 PFAM: YHS domain protein; KEGG: mpo:Mpop_2554 heavy metal translocating P-type ATPase; YHS domain-containing protein 1035746 7118516 Mchl_1013 Methylobacterium extorquens CM4 YHS domain-containing protein YP_002419852.1 1034898 R 440085 CDS YP_002419853.1 218529037 7118517 complement(1035834..1036586) 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mpo:Mpop_2555 lytic transglycosylase catalytic; lytic transglycosylase 1036586 7118517 Mchl_1014 Methylobacterium extorquens CM4 lytic transglycosylase YP_002419853.1 1035834 R 440085 CDS YP_002419854.1 218529038 7118518 complement(1036725..1037129) 1 NC_011757.1 KEGG: mpo:Mpop_2577 hypothetical protein; hypothetical protein 1037129 7118518 Mchl_1015 Methylobacterium extorquens CM4 hypothetical protein YP_002419854.1 1036725 R 440085 CDS YP_002419855.1 218529039 7118519 complement(1037210..1037662) 1 NC_011757.1 KEGG: mpo:Mpop_2557 conserved hypothetical protein; exported protein; hypothetical protein 1037662 7118519 Mchl_1016 Methylobacterium extorquens CM4 hypothetical protein YP_002419855.1 1037210 R 440085 CDS YP_002419856.1 218529040 7118521 complement(1038324..1038794) 1 NC_011757.1 PFAM: protein of unknown function DUF411; KEGG: mpo:Mpop_2562 protein of unknown function DUF411; hypothetical protein 1038794 7118521 Mchl_1018 Methylobacterium extorquens CM4 hypothetical protein YP_002419856.1 1038324 R 440085 CDS YP_002419857.1 218529041 7118522 complement(1038850..1042014) 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_2563 heavy metal efflux pump, CzcA family; CzcA family heavy metal efflux pump 1042014 7118522 Mchl_1019 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002419857.1 1038850 R 440085 CDS YP_002419858.1 218529042 7118523 complement(1042011..1043537) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mpo:Mpop_2564 efflux transporter RND family, MFP subunit; efflux transporter RND family MFP subunit 1043537 7118523 Mchl_1020 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002419858.1 1042011 R 440085 CDS YP_002419859.1 218529043 7118524 complement(1043537..1044085) 1 NC_011757.1 KEGG: mpo:Mpop_2565 hypothetical protein; hypothetical protein 1044085 7118524 Mchl_1021 Methylobacterium extorquens CM4 hypothetical protein YP_002419859.1 1043537 R 440085 CDS YP_002419860.1 218529044 7118525 complement(1044868..1045152) 1 NC_011757.1 KEGG: mpo:Mpop_2567 hypothetical protein; hypothetical protein 1045152 7118525 Mchl_1022 Methylobacterium extorquens CM4 hypothetical protein YP_002419860.1 1044868 R 440085 CDS YP_002419861.1 218529045 7118526 1046011..1046283 1 NC_011757.1 KEGG: mpo:Mpop_2571 hypothetical protein; hypothetical protein 1046283 7118526 Mchl_1023 Methylobacterium extorquens CM4 hypothetical protein YP_002419861.1 1046011 D 440085 CDS YP_002419862.1 218529046 7118527 complement(1046328..1046978) 1 NC_011757.1 PFAM: protein of unknown function DUF1109; KEGG: mpo:Mpop_2572 protein of unknown function DUF1109; hypothetical protein 1046978 7118527 Mchl_1024 Methylobacterium extorquens CM4 hypothetical protein YP_002419862.1 1046328 R 440085 CDS YP_002419863.1 218529047 7118528 complement(1046975..1047529) 1 NC_011757.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1047529 7118528 Mchl_1025 Methylobacterium extorquens CM4 RNA polymerase sigma factor YP_002419863.1 1046975 R 440085 CDS YP_002419864.1 218529048 7118529 complement(1047998..1048213) 1 NC_011757.1 hypothetical protein 1048213 7118529 Mchl_1026 Methylobacterium extorquens CM4 hypothetical protein YP_002419864.1 1047998 R 440085 CDS YP_002419865.1 218529049 7118530 1048542..1048913 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: mpo:Mpop_2575 hypothetical protein; hypothetical protein 1048913 7118530 Mchl_1027 Methylobacterium extorquens CM4 hypothetical protein YP_002419865.1 1048542 D 440085 CDS YP_002419866.1 218529050 7118531 1050202..1050654 1 NC_011757.1 KEGG: mpo:Mpop_2557 conserved hypothetical protein; exported protein; hypothetical protein 1050654 7118531 Mchl_1028 Methylobacterium extorquens CM4 hypothetical protein YP_002419866.1 1050202 D 440085 CDS YP_002419867.1 218529051 7118532 1050735..1051139 1 NC_011757.1 KEGG: mpo:Mpop_2577 hypothetical protein; hypothetical protein 1051139 7118532 Mchl_1029 Methylobacterium extorquens CM4 hypothetical protein YP_002419867.1 1050735 D 440085 CDS YP_002419868.1 218529052 7118533 1051139..1052746 1 NC_011757.1 KEGG: mpo:Mpop_2578 outer membrane efflux protein; outer membrane efflux protein 1052746 7118533 Mchl_1030 Methylobacterium extorquens CM4 outer membrane efflux protein YP_002419868.1 1051139 D 440085 CDS YP_002419869.1 218529053 7118534 1052779..1054200 1 NC_011757.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: mpo:Mpop_2579 multicopper oxidase type 3; multicopper oxidase type 3 1054200 7118534 Mchl_1031 Methylobacterium extorquens CM4 multicopper oxidase type 3 YP_002419869.1 1052779 D 440085 CDS YP_002419870.1 218529054 7118535 1054375..1054659 1 NC_011757.1 KEGG: mpo:Mpop_2580 hypothetical protein; hypothetical protein 1054659 7118535 Mchl_1032 Methylobacterium extorquens CM4 hypothetical protein YP_002419870.1 1054375 D 440085 CDS YP_002419871.1 218529055 7118536 1054731..1055435 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: mpo:Mpop_2581 hypothetical protein; hypothetical protein 1055435 7118536 Mchl_1033 Methylobacterium extorquens CM4 hypothetical protein YP_002419871.1 1054731 D 440085 CDS YP_002419872.1 218529056 7118537 1055541..1056179 1 NC_011757.1 KEGG: mpo:Mpop_2582 cytochrome C family protein; cytochrome C family protein 1056179 7118537 Mchl_1034 Methylobacterium extorquens CM4 cytochrome C family protein YP_002419872.1 1055541 D 440085 CDS YP_002419873.1 218529057 7118538 1056313..1056693 1 NC_011757.1 KEGG: mpo:Mpop_2584 hypothetical protein; hypothetical protein 1056693 7118538 Mchl_1035 Methylobacterium extorquens CM4 hypothetical protein YP_002419873.1 1056313 D 440085 CDS YP_002419874.1 218529058 7118540 1057056..1057343 1 NC_011757.1 KEGG: hip:CGSHiEE_04655 hypothetical protein; hypothetical protein 1057343 7118540 Mchl_1037 Methylobacterium extorquens CM4 hypothetical protein YP_002419874.1 1057056 D 440085 CDS YP_002419875.1 218529059 7118543 1058436..1059101 1 NC_011757.1 KEGG: mrd:Mrad2831_6454 hypothetical protein; hypothetical protein 1059101 7118543 Mchl_1040 Methylobacterium extorquens CM4 hypothetical protein YP_002419875.1 1058436 D 440085 CDS YP_002419876.1 218529060 7118544 1059302..1059658 1 NC_011757.1 KEGG: rme:Rmet_3038 hypothetical protein; hypothetical protein 1059658 7118544 Mchl_1041 Methylobacterium extorquens CM4 hypothetical protein YP_002419876.1 1059302 D 440085 CDS YP_002419877.1 218529061 7118545 1059655..1060446 1 NC_011757.1 PFAM: MOFRL domain protein; KEGG: mpo:Mpop_4659 hydroxypyruvate reductase; hydroxypyruvate reductase 1060446 7118545 Mchl_1042 Methylobacterium extorquens CM4 hydroxypyruvate reductase YP_002419877.1 1059655 D 440085 CDS YP_002419878.1 218529062 7118546 1060471..1061898 1 NC_011757.1 KEGG: mrd:Mrad2831_3358 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; pyruvate kinase 1061898 7118546 Mchl_1043 Methylobacterium extorquens CM4 pyruvate kinase YP_002419878.1 1060471 D 440085 CDS YP_002419879.1 218529063 7118547 1062349..1062561 1 NC_011757.1 KEGG: mpo:Mpop_1896 hypothetical protein; hypothetical protein 1062561 7118547 Mchl_1044 Methylobacterium extorquens CM4 hypothetical protein YP_002419879.1 1062349 D 440085 CDS YP_002419880.1 218529064 7118548 complement(1062609..1063355) 1 NC_011757.1 TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_3863 arsenical resistance protein ArsH; arsenical resistance protein ArsH 1063355 7118548 Mchl_1045 Methylobacterium extorquens CM4 arsenical resistance protein ArsH YP_002419880.1 1062609 R 440085 CDS YP_002419881.1 218529065 7118549 1063406..1063765 1 NC_011757.1 SMART: regulatory protein ArsR; KEGG: mpo:Mpop_4055 ArsR family transcriptional regulator; ArsR family transcriptional regulator 1063765 7118549 Mchl_1046 Methylobacterium extorquens CM4 ArsR family transcriptional regulator YP_002419881.1 1063406 D 440085 CDS YP_002419882.1 218529066 7118550 1063758..1064285 1 NC_011757.1 PFAM: protein-tyrosine phosphatase, low molecular weight; KEGG: mpo:Mpop_4054 protein tyrosine phosphatase; protein-tyrosine phosphatase, low molecular weight 1064285 7118550 Mchl_1047 Methylobacterium extorquens CM4 protein-tyrosine phosphatase, low molecular weight YP_002419882.1 1063758 D 440085 CDS YP_002419883.1 218529067 7118551 1064285..1064710 1 NC_011757.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: mpo:Mpop_4053 arsenate reductase; arsenate reductase 1064710 7118551 Mchl_1048 Methylobacterium extorquens CM4 arsenate reductase YP_002419883.1 1064285 D 440085 CDS YP_002419884.1 218529068 7118552 1064720..1065787 1 NC_011757.1 TIGRFAM: arsenic resistance protein; PFAM: Bile acid:sodium symporter; KEGG: mpo:Mpop_4052 arsenic resistance protein; arsenic resistance protein 1065787 7118552 Mchl_1049 Methylobacterium extorquens CM4 arsenic resistance protein YP_002419884.1 1064720 D 440085 CDS YP_002419885.1 218529069 7118553 1065777..1066952 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1916 major facilitator transporter; major facilitator superfamily protein 1066952 7118553 Mchl_1050 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419885.1 1065777 D 440085 CDS YP_002419886.1 218529070 7118554 1067140..1067412 1 NC_011757.1 KEGG: bra:BRADO0700 hypothetical protein; hypothetical protein 1067412 7118554 Mchl_1051 Methylobacterium extorquens CM4 hypothetical protein YP_002419886.1 1067140 D 440085 CDS YP_002419887.1 218529071 7118555 1067543..1070701 1 NC_011757.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: nha:Nham_2657 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 1070701 7118555 Mchl_1052 Methylobacterium extorquens CM4 peptidase S8/S53 subtilisin kexin sedolisin YP_002419887.1 1067543 D 440085 CDS YP_002419888.1 218529072 7118557 1071109..1071384 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: mpo:Mpop_3816 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1071384 7118557 Mchl_1054 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002419888.1 1071109 D 440085 CDS YP_002419889.1 218529073 7118558 1071423..1072292 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mpo:Mpop_3817 integrase catalytic region; integrase catalytic subunit 1072292 7118558 Mchl_1055 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002419889.1 1071423 D 440085 CDS YP_002419890.1 218529074 7118560 complement(1072449..1073129) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_0458 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 1073129 7118560 Mchl_1057 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002419890.1 1072449 R 440085 CDS YP_002419891.1 218529075 7118561 complement(1073610..1075199) 1 NC_011757.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: rpt:Rpal_1106 filamentation induced by cAMP protein Fic; filamentation induced by cAMP protein Fic 1075199 7118561 Mchl_1058 Methylobacterium extorquens CM4 filamentation induced by cAMP protein Fic YP_002419891.1 1073610 R 440085 CDS YP_002419892.1 218529076 7118565 1076428..1076736 1 NC_011757.1 KEGG: mrd:Mrad2831_2559 cytochrome C biogenesis protein transmembrane region; cytochrome C biogenesis protein transmembrane region 1076736 7118565 Mchl_1062 Methylobacterium extorquens CM4 cytochrome C biogenesis protein transmembrane region YP_002419892.1 1076428 D 440085 CDS YP_002419893.1 218529077 7118566 complement(1078294..1079715) 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: nha:Nham_2969 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 1079715 7118566 Mchl_1063 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002419893.1 1078294 R 440085 CDS YP_002419894.1 218529078 7118567 1080386..1080964 1 NC_011757.1 KEGG: bvi:Bcep1808_7510 hypothetical protein; hypothetical protein 1080964 7118567 Mchl_1064 Methylobacterium extorquens CM4 hypothetical protein YP_002419894.1 1080386 D 440085 CDS YP_002419895.1 218529079 7118568 complement(1080874..1081683) 1 NC_011757.1 hypothetical protein 1081683 7118568 Mchl_1065 Methylobacterium extorquens CM4 hypothetical protein YP_002419895.1 1080874 R 440085 CDS YP_002419896.1 218529080 7118569 1082245..1082979 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mpo:Mpop_4076 transcriptional regulator; transcriptional regulator 1082979 7118569 Mchl_1066 Methylobacterium extorquens CM4 transcriptional regulator YP_002419896.1 1082245 D 440085 CDS YP_002419897.1 218529081 7118570 1082976..1084310 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mpo:Mpop_4077 integral membrane sensor signal transduction histidine kinase; histidine kinase 1084310 7118570 Mchl_1067 Methylobacterium extorquens CM4 histidine kinase YP_002419897.1 1082976 D 440085 CDS YP_002419898.1 218529082 7118571 1084407..1084661 1 NC_011757.1 KEGG: mpo:Mpop_4079 hypothetical protein; hypothetical protein 1084661 7118571 Mchl_1068 Methylobacterium extorquens CM4 hypothetical protein YP_002419898.1 1084407 D 440085 CDS YP_002419899.1 218529083 7118572 1085224..1085415 1 NC_011757.1 hypothetical protein 1085415 7118572 Mchl_1069 Methylobacterium extorquens CM4 hypothetical protein YP_002419899.1 1085224 D 440085 CDS YP_002419900.1 218529084 7118573 1085760..1086131 1 NC_011757.1 KEGG: mrd:Mrad2831_1404 hypothetical protein; hypothetical protein 1086131 7118573 Mchl_1070 Methylobacterium extorquens CM4 hypothetical protein YP_002419900.1 1085760 D 440085 CDS YP_002419901.1 218529085 7118574 1086256..1087620 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mpo:Mpop_4082 efflux transporter RND family, MFP subunit; efflux transporter RND family MFP subunit 1087620 7118574 Mchl_1071 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002419901.1 1086256 D 440085 CDS YP_002419902.1 218529086 7118575 1087632..1090880 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_4083 heavy metal efflux pump, CzcA family; CzcA family heavy metal efflux pump 1090880 7118575 Mchl_1072 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002419902.1 1087632 D 440085 CDS YP_002419903.1 218529087 7118576 1090886..1091440 1 NC_011757.1 KEGG: mpo:Mpop_4085 hypothetical protein; hypothetical protein 1091440 7118576 Mchl_1073 Methylobacterium extorquens CM4 hypothetical protein YP_002419903.1 1090886 D 440085 CDS YP_002419904.1 218529088 7118577 1091486..1092403 1 NC_011757.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mpo:Mpop_4086 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 1092403 7118577 Mchl_1074 Methylobacterium extorquens CM4 cation diffusion facilitator family transporter YP_002419904.1 1091486 D 440085 CDS YP_002419905.1 218529089 7118578 1092416..1092586 1 NC_011757.1 KEGG: mpo:Mpop_4087 hypothetical protein; hypothetical protein 1092586 7118578 Mchl_1075 Methylobacterium extorquens CM4 hypothetical protein YP_002419905.1 1092416 D 440085 CDS YP_002419906.1 218529090 7118579 1092909..1093163 1 NC_011757.1 KEGG: xau:Xaut_0674 hypothetical protein; hypothetical protein 1093163 7118579 Mchl_1076 Methylobacterium extorquens CM4 hypothetical protein YP_002419906.1 1092909 D 440085 CDS YP_002419907.1 218529091 7118580 1093402..1093542 1 NC_011757.1 hypothetical protein 1093542 7118580 Mchl_1077 Methylobacterium extorquens CM4 hypothetical protein YP_002419907.1 1093402 D 440085 CDS YP_002419908.1 218529092 7118581 complement(1093539..1095083) 1 NC_011757.1 KEGG: mes:Meso_4409 hypothetical protein; hypothetical protein 1095083 7118581 Mchl_1078 Methylobacterium extorquens CM4 hypothetical protein YP_002419908.1 1093539 R 440085 CDS YP_002419909.1 218529093 7118582 complement(1095286..1096026) 1 NC_011757.1 PFAM: protein of unknown function DUF1526; KEGG: mag:amb1131 hypothetical protein; hypothetical protein 1096026 7118582 Mchl_1079 Methylobacterium extorquens CM4 hypothetical protein YP_002419909.1 1095286 R 440085 CDS YP_002419910.1 218529094 7118583 complement(1096596..1096802) 1 NC_011757.1 hypothetical protein 1096802 7118583 Mchl_1080 Methylobacterium extorquens CM4 hypothetical protein YP_002419910.1 1096596 R 440085 CDS YP_002419911.1 218529095 7118585 complement(1097275..1098144) 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mpo:Mpop_3817 integrase catalytic region; integrase catalytic subunit 1098144 7118585 Mchl_1082 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002419911.1 1097275 R 440085 CDS YP_002419912.1 218529096 7118586 complement(1098183..1098458) 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: mpo:Mpop_3816 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1098458 7118586 Mchl_1083 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002419912.1 1098183 R 440085 CDS YP_002419913.1 218529097 7118587 complement(1098507..1098647) 1 NC_011757.1 KEGG: mrd:Mrad2831_4774 pentapeptide repeat-containing protein; pentapeptide repeat-containing protein 1098647 7118587 Mchl_1084 Methylobacterium extorquens CM4 pentapeptide repeat-containing protein YP_002419913.1 1098507 R 440085 CDS YP_002419914.1 218529098 7118588 1099221..1099511 1 NC_011757.1 KEGG: mpo:Mpop_3234 integrase family protein; integrase family protein 1099511 7118588 Mchl_1085 Methylobacterium extorquens CM4 integrase family protein YP_002419914.1 1099221 D 440085 CDS YP_002419915.1 218529099 7118589 1099508..1100062 1 NC_011757.1 KEGG: mpo:Mpop_3233 integrase family protein; hypothetical protein 1100062 7118589 Mchl_1086 Methylobacterium extorquens CM4 hypothetical protein YP_002419915.1 1099508 D 440085 CDS YP_002419916.1 218529100 7118590 complement(1100964..1101317) 1 NC_011757.1 KEGG: gur:Gura_4266 hypothetical protein; hypothetical protein 1101317 7118590 Mchl_1087 Methylobacterium extorquens CM4 hypothetical protein YP_002419916.1 1100964 R 440085 CDS YP_002419917.1 218529101 7118591 complement(1101432..1102391) 1 NC_011757.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: acr:Acry_3394 transposase IS116/IS110/IS902 family protein; transposase IS116/IS110/IS902 family protein 1102391 7118591 Mchl_1088 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002419917.1 1101432 R 440085 CDS YP_002419918.1 218529102 7118592 1102478..1103338 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mrd:Mrad2831_6485 integrase catalytic region; integrase catalytic subunit 1103338 7118592 Mchl_1089 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002419918.1 1102478 D 440085 CDS YP_002419919.1 218529103 7118593 join(1103497..1103838,1103838..1104458) 1 NC_011757.1 KEGG: mrd:Mrad2831_5182 transposase; transposase 1104458 7118593 Mchl_1090 Methylobacterium extorquens CM4 transposase YP_002419919.1 1103497 D 440085 CDS YP_002419920.1 218529104 7117210 complement(1105389..1105577) 1 NC_011757.1 KEGG: mpo:Mpop_4120 cytochrome C biogenesis protein transmembrane region; cytochrome C biogenesis protein transmembrane region 1105577 7117210 Mchl_1093 Methylobacterium extorquens CM4 cytochrome C biogenesis protein transmembrane region YP_002419920.1 1105389 R 440085 CDS YP_002419921.1 218529105 7117211 complement(1105718..1106791) 1 NC_011757.1 KEGG: mpo:Mpop_4119 protein of unknown function DUF949; hypothetical protein 1106791 7117211 Mchl_1094 Methylobacterium extorquens CM4 hypothetical protein YP_002419921.1 1105718 R 440085 CDS YP_002419922.1 218529106 7117212 complement(1106880..1107398) 1 NC_011757.1 TIGRFAM: lipoprotein signal peptidase; KEGG: mpo:Mpop_4118 peptidase A8 signal peptidase II; lipoprotein signal peptidase 1107398 7117212 Mchl_1095 Methylobacterium extorquens CM4 lipoprotein signal peptidase YP_002419922.1 1106880 R 440085 CDS YP_002419923.1 218529107 7117213 complement(1107398..1109593) 1 NC_011757.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: mpo:Mpop_4117 ATPase P; ATPase P 1109593 7117213 Mchl_1096 Methylobacterium extorquens CM4 ATPase P YP_002419923.1 1107398 R 440085 CDS YP_002419924.1 218529108 7117214 1109694..1110095 1 NC_011757.1 PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: mpo:Mpop_4116 MerR family transcriptional regulator; MerR family transcriptional regulator 1110095 7117214 Mchl_1097 Methylobacterium extorquens CM4 MerR family transcriptional regulator YP_002419924.1 1109694 D 440085 CDS YP_002419925.1 218529109 7117215 complement(1110772..1113192) 1 NC_011757.1 KEGG: mpo:Mpop_4130 copper-translocating P-type ATPase; TIGRFAM: ATPase P; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein; copper-translocating P-type ATPase 1113192 7117215 Mchl_1098 Methylobacterium extorquens CM4 copper-translocating P-type ATPase YP_002419925.1 1110772 R 440085 CDS YP_002419926.1 218529110 7117216 complement(1113260..1113742) 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: sme:SMa1024 hypothetical protein; hypothetical protein 1113742 7117216 Mchl_1099 Methylobacterium extorquens CM4 hypothetical protein YP_002419926.1 1113260 R 440085 CDS YP_002419927.1 218529111 7117217 complement(1113797..1114129) 1 NC_011757.1 KEGG: mpo:Mpop_2537 protein of unknown function DUF326; hypothetical protein 1114129 7117217 Mchl_1100 Methylobacterium extorquens CM4 hypothetical protein YP_002419927.1 1113797 R 440085 CDS YP_002419928.1 218529112 7117218 complement(1114309..1114707) 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: mpo:Mpop_0108 protein of unknown function DUF305; hypothetical protein 1114707 7117218 Mchl_1101 Methylobacterium extorquens CM4 hypothetical protein YP_002419928.1 1114309 R 440085 CDS YP_002419929.1 218529113 7117219 complement(1114734..1115099) 1 NC_011757.1 KEGG: mpo:Mpop_0109 hypothetical protein; hypothetical protein 1115099 7117219 Mchl_1102 Methylobacterium extorquens CM4 hypothetical protein YP_002419929.1 1114734 R 440085 CDS YP_002419930.1 218529114 7117220 complement(1115119..1118268) 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_0110 heavy metal efflux pump, CzcA family; CzcA family heavy metal efflux pump 1118268 7117220 Mchl_1103 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002419930.1 1115119 R 440085 CDS YP_002419931.1 218529115 7117221 complement(1118282..1120021) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: mpo:Mpop_4125 efflux transporter RND family, MFP subunit; efflux transporter RND family MFP subunit 1120021 7117221 Mchl_1104 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002419931.1 1118282 R 440085 CDS YP_002419932.1 218529116 7117222 complement(1120107..1120577) 1 NC_011757.1 KEGG: mpo:Mpop_0112 hypothetical protein; hypothetical protein 1120577 7117222 Mchl_1105 Methylobacterium extorquens CM4 hypothetical protein YP_002419932.1 1120107 R 440085 CDS YP_002419933.1 218529117 7117223 complement(1120669..1120881) 1 NC_011757.1 KEGG: mrd:Mrad2831_2531 heavy metal transport/detoxification protein; heavy metal transport/detoxification protein 1120881 7117223 Mchl_1106 Methylobacterium extorquens CM4 heavy metal transport/detoxification protein YP_002419933.1 1120669 R 440085 CDS YP_002419934.1 218529118 7117224 1121262..1122002 1 NC_011757.1 KEGG: mpo:Mpop_4114 hypothetical protein; hypothetical protein 1122002 7117224 Mchl_1107 Methylobacterium extorquens CM4 hypothetical protein YP_002419934.1 1121262 D 440085 CDS YP_002419935.1 218529119 7117225 complement(1122016..1122492) 1 NC_011757.1 PFAM: protein of unknown function DUF411; KEGG: mpo:Mpop_4113 protein of unknown function DUF411; hypothetical protein 1122492 7117225 Mchl_1108 Methylobacterium extorquens CM4 hypothetical protein YP_002419935.1 1122016 R 440085 CDS YP_002419936.1 218529120 7117226 complement(1122512..1125685) 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_4112 heavy metal efflux pump, CzcA family; CzcA family heavy metal efflux pump 1125685 7117226 Mchl_1109 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002419936.1 1122512 R 440085 CDS YP_002419937.1 218529121 7117228 1126106..1126372 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: dde:Dde_2906 Fis family transcriptional regulator; transposase IS3/IS911 family protein 1126372 7117228 Mchl_1111 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002419937.1 1126106 D 440085 CDS YP_002419938.1 218529122 7117229 1126423..1127205 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: bcj:BCAM1952 transposase; integrase catalytic subunit 1127205 7117229 Mchl_1112 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002419938.1 1126423 D 440085 CDS YP_002419939.1 218529123 7117230 1128136..1128330 1 NC_011757.1 hypothetical protein 1128330 7117230 Mchl_1113 Methylobacterium extorquens CM4 hypothetical protein YP_002419939.1 1128136 D 440085 CDS YP_002419940.1 218529124 7117231 complement(1128387..1128608) 1 NC_011757.1 hypothetical protein 1128608 7117231 Mchl_1114 Methylobacterium extorquens CM4 hypothetical protein YP_002419940.1 1128387 R 440085 CDS YP_002419941.1 218529125 7117232 1129021..1129425 1 NC_011757.1 KEGG: LOC100030415; hypothetical protein LOC100030415; hypothetical protein 1129425 7117232 Mchl_1115 Methylobacterium extorquens CM4 hypothetical protein YP_002419941.1 1129021 D 440085 CDS YP_002419942.1 218529126 7117235 complement(1129995..1130426) 1 NC_011757.1 KEGG: mpo:Mpop_4084 exported protein of unknown function; hypothetical protein 1130426 7117235 Mchl_1118 Methylobacterium extorquens CM4 hypothetical protein YP_002419942.1 1129995 R 440085 CDS YP_002419943.1 218529127 7117237 1132102..1132305 1 NC_011757.1 hypothetical protein 1132305 7117237 Mchl_1120 Methylobacterium extorquens CM4 hypothetical protein YP_002419943.1 1132102 D 440085 CDS YP_002419944.1 218529128 7117238 complement(1132225..1132494) 1 NC_011757.1 KEGG: mrd:Mrad2831_0880 hypothetical protein; hypothetical protein 1132494 7117238 Mchl_1121 Methylobacterium extorquens CM4 hypothetical protein YP_002419944.1 1132225 R 440085 CDS YP_002419945.1 218529129 7117239 complement(1132650..1133918) 1 NC_011757.1 PFAM: transposase mutator type; KEGG: mrd:Mrad2831_2616 transposase mutator type; transposase mutator type 1133918 7117239 Mchl_1122 Methylobacterium extorquens CM4 transposase mutator type YP_002419945.1 1132650 R 440085 CDS YP_002419946.1 218529130 7117241 1135126..1135407 1 NC_011757.1 PFAM: plasmid maintenance system killer; KEGG: mpo:Mpop_3936 plasmid maintenance system killer; plasmid maintenance system killer 1135407 7117241 Mchl_1124 Methylobacterium extorquens CM4 plasmid maintenance system killer YP_002419946.1 1135126 D 440085 CDS YP_002419947.1 218529131 7117242 1135480..1135839 1 NC_011757.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: mpo:Mpop_3935 plasmid maintenance system antidote protein, XRE family; XRE family transcriptional regulator 1135839 7117242 Mchl_1125 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419947.1 1135480 D 440085 CDS YP_002419948.1 218529132 7117243 1135843..1136205 1 NC_011757.1 hypothetical protein 1136205 7117243 Mchl_1126 Methylobacterium extorquens CM4 hypothetical protein YP_002419948.1 1135843 D 440085 CDS YP_002419949.1 218529133 7117244 1136234..1137166 1 NC_011757.1 KEGG: rpt:Rpal_3729 hypothetical protein; hypothetical protein 1137166 7117244 Mchl_1127 Methylobacterium extorquens CM4 hypothetical protein YP_002419949.1 1136234 D 440085 CDS YP_002419950.1 218529134 7117245 complement(1137229..1137741) 1 NC_011757.1 hypothetical protein 1137741 7117245 Mchl_1128 Methylobacterium extorquens CM4 hypothetical protein YP_002419950.1 1137229 R 440085 CDS YP_002419951.1 218529135 7117246 complement(1138139..1138387) 1 NC_011757.1 KEGG: mex:Mext_4519 hypothetical protein; hypothetical protein 1138387 7117246 Mchl_1129 Methylobacterium extorquens CM4 hypothetical protein YP_002419951.1 1138139 R 440085 CDS YP_002419952.1 218529136 7117249 1138976..1139269 1 NC_011757.1 KEGG: shl:Shal_1751 hypothetical protein; hypothetical protein 1139269 7117249 Mchl_1132 Methylobacterium extorquens CM4 hypothetical protein YP_002419952.1 1138976 D 440085 CDS YP_002419953.1 218529137 7117251 complement(1139989..1140882) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO4000 OprD regulatory protein; LysR family transcriptional regulator 1140882 7117251 Mchl_1134 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002419953.1 1139989 R 440085 CDS YP_002419954.1 218529138 7117252 1141015..1141410 1 NC_011757.1 PFAM: cupin; KEGG: bbt:BBta_2281 transcriptional regulator; cupin 1141410 7117252 Mchl_1135 Methylobacterium extorquens CM4 cupin YP_002419954.1 1141015 D 440085 CDS YP_002419955.1 218529139 7117253 1141508..1142734 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: bch:Bcen2424_6467 major facilitator transporter; major facilitator superfamily protein 1142734 7117253 Mchl_1136 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419955.1 1141508 D 440085 CDS YP_002419956.1 218529140 7117254 1142806..1143573 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bid:Bind_1760 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1143573 7117254 Mchl_1137 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002419956.1 1142806 D 440085 CDS YP_002419957.1 218529141 7117255 1143585..1144088 1 NC_011757.1 KEGG: ank:AnaeK_3353 hypothetical protein; hypothetical protein 1144088 7117255 Mchl_1138 Methylobacterium extorquens CM4 hypothetical protein YP_002419957.1 1143585 D 440085 CDS YP_002419958.1 218529142 7117259 complement(1146608..1147501) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO4000 OprD regulatory protein; LysR family transcriptional regulator 1147501 7117259 Mchl_1142 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002419958.1 1146608 R 440085 CDS YP_002419959.1 218529143 7117260 1147749..1148384 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; aldehyde dehydrogenase, conserved site; KEGG: mrd:Mrad2831_4261 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 1148384 7117260 Mchl_1143 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002419959.1 1147749 D 440085 CDS YP_002419960.1 218529144 7117261 1148381..1149331 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mrd:Mrad2831_4262 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 1149331 7117261 Mchl_1144 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002419960.1 1148381 D 440085 CDS YP_002419961.1 218529145 7117262 1149335..1151554 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mrd:Mrad2831_4263 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 1151554 7117262 Mchl_1145 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002419961.1 1149335 D 440085 CDS YP_002419962.1 218529146 7117263 1151564..1152058 1 NC_011757.1 PFAM: cupin; KEGG: bxe:Bxe_B1954 hypothetical protein; cupin 1152058 7117263 Mchl_1146 Methylobacterium extorquens CM4 cupin YP_002419962.1 1151564 D 440085 CDS YP_002419963.1 218529147 7117264 1152113..1152289 1 NC_011757.1 hypothetical protein 1152289 7117264 Mchl_1147 Methylobacterium extorquens CM4 hypothetical protein YP_002419963.1 1152113 D 440085 CDS YP_002419964.1 218529148 7117265 complement(1152326..1152820) 1 NC_011757.1 hypothetical protein 1152820 7117265 Mchl_1148 Methylobacterium extorquens CM4 hypothetical protein YP_002419964.1 1152326 R 440085 CDS YP_002419965.1 218529149 7117266 1153975..1155009 1 NC_011757.1 PFAM: GTPase EngC; KEGG: mex:Mext_1006 GTPase EngC; GTPase EngC 1155009 7117266 Mchl_1149 Methylobacterium extorquens CM4 GTPase EngC YP_002419965.1 1153975 D 440085 CDS YP_002419966.1 218529150 7117273 1161631..1163724 1 NC_011757.1 PFAM: peptidase M23; KEGG: mex:Mext_1023 peptidase M23B; peptidase M23 1163724 7117273 Mchl_1150 Methylobacterium extorquens CM4 peptidase M23 YP_002419966.1 1161631 D 440085 CDS YP_002419967.1 218529151 7117274 complement(1163747..1164259) 1 NC_011757.1 PFAM: protein of unknown function DUF1311; KEGG: mex:Mext_1024 hypothetical protein; hypothetical protein 1164259 7117274 Mchl_1151 Methylobacterium extorquens CM4 hypothetical protein YP_002419967.1 1163747 R 440085 CDS YP_002419968.1 218529152 7117275 complement(1164326..1165216) 1 NC_011757.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: mex:Mext_1025 glutamyl-tRNA synthetase class Ic; glutamyl-tRNA synthetase class Ic 1165216 7117275 Mchl_1152 Methylobacterium extorquens CM4 glutamyl-tRNA synthetase class Ic YP_002419968.1 1164326 R 440085 CDS YP_002419969.1 218529153 7117276 complement(1165249..1165548) 1 NC_011757.1 KEGG: mex:Mext_1026 hypothetical protein; hypothetical protein 1165548 7117276 Mchl_1153 Methylobacterium extorquens CM4 hypothetical protein YP_002419969.1 1165249 R 440085 CDS YP_002419970.1 218529154 7117277 1165772..1165990 1 NC_011757.1 KEGG: mpo:Mpop_0959 hypothetical protein; hypothetical protein 1165990 7117277 Mchl_1154 Methylobacterium extorquens CM4 hypothetical protein YP_002419970.1 1165772 D 440085 CDS YP_002419971.1 218529155 7117278 complement(1166013..1167893) 1 NC_011757.1 molecular chaperone; heat shock protein 90 1167893 7117278 Mchl_1155 Methylobacterium extorquens CM4 heat shock protein 90 YP_002419971.1 1166013 R 440085 CDS YP_002419972.1 218529156 7117279 complement(1168048..1168362) 1 NC_011757.1 KEGG: mex:Mext_1029 hypothetical protein; hypothetical protein 1168362 7117279 Mchl_1156 Methylobacterium extorquens CM4 hypothetical protein YP_002419972.1 1168048 R 440085 CDS YP_002419973.1 218529157 7117280 1168678..1170273 1 NC_011757.1 PFAM: gamma-glutamyltranspeptidase; KEGG: mex:Mext_1030 gamma-glutamyltransferase; gamma-glutamyltransferase 1170273 7117280 Mchl_1157 Methylobacterium extorquens CM4 gamma-glutamyltransferase YP_002419973.1 1168678 D 440085 CDS YP_002419974.1 218529158 7117281 1170376..1172013 1 NC_011757.1 PFAM: Dak kinase; Dak phosphatase; KEGG: mex:Mext_1031 glycerone kinase; glycerone kinase 1172013 7117281 Mchl_1158 Methylobacterium extorquens CM4 glycerone kinase YP_002419974.1 1170376 D 440085 CDS YP_002419975.1 218529159 7117282 1172022..1172870 1 NC_011757.1 PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_1032 methyltransferase type 11; type 11 methyltransferase 1172870 7117282 Mchl_1159 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002419975.1 1172022 D 440085 CDS YP_002419976.1 218529160 7117283 1172926..1174218 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1033 major facilitator transporter; major facilitator superfamily protein 1174218 7117283 Mchl_1160 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419976.1 1172926 D 440085 CDS YP_002419977.1 218529161 7117284 1174337..1175572 1 NC_011757.1 KEGG: mex:Mext_1034 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6y C5,15-methyltransferase subunit CbiE 1175572 7117284 Mchl_1161 Methylobacterium extorquens CM4 precorrin-6y C5,15-methyltransferase subunit CbiE YP_002419977.1 1174337 D 440085 CDS YP_002419978.1 218529162 7117285 1175551..1175976 1 NC_011757.1 KEGG: mex:Mext_1035 CobE protein; CobE protein 1175976 7117285 Mchl_1162 Methylobacterium extorquens CM4 CobE protein YP_002419978.1 1175551 D 440085 CDS YP_002419979.1 218529163 7117286 1176064..1177155 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_1036 diguanylate cyclase; diguanylate cyclase 1177155 7117286 Mchl_1163 Methylobacterium extorquens CM4 diguanylate cyclase YP_002419979.1 1176064 D 440085 CDS YP_002419980.1 218529164 7117287 complement(1177217..1178125) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1037 LysR substrate-binding; LysR family transcriptional regulator 1178125 7117287 Mchl_1164 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002419980.1 1177217 R 440085 CDS YP_002419981.1 218529165 7117288 1178235..1178678 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_1038 transmembrane pair domain-containing protein; hypothetical protein 1178678 7117288 Mchl_1165 Methylobacterium extorquens CM4 hypothetical protein YP_002419981.1 1178235 D 440085 CDS YP_002419982.1 218529166 7117289 1178759..1179559 1 NC_011757.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mex:Mext_1039 precorrin-4 C11-methyltransferase; precorrin-4 C11-methyltransferase 1179559 7117289 Mchl_1166 Methylobacterium extorquens CM4 precorrin-4 C11-methyltransferase YP_002419982.1 1178759 D 440085 CDS YP_002419983.1 218529167 7114694 1179556..1180881 1 NC_011757.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1180881 7114694 Mchl_1167 Methylobacterium extorquens CM4 cobyrinic acid a,c-diamide synthase YP_002419983.1 1179556 D 440085 CDS YP_002419984.1 218529168 7117862 complement(1181147..1181575) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_1041 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 1181575 7117862 Mchl_1168 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002419984.1 1181147 R 440085 CDS YP_002419985.1 218529169 7117863 1182026..1182361 1 NC_011757.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: mex:Mext_1042 antibiotic biosynthesis monooxygenase; antibiotic biosynthesis monooxygenase 1182361 7117863 Mchl_1169 Methylobacterium extorquens CM4 antibiotic biosynthesis monooxygenase YP_002419985.1 1182026 D 440085 CDS YP_002419986.1 218529170 7117864 complement(1182489..1183736) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1043 major facilitator transporter; major facilitator superfamily protein 1183736 7117864 Mchl_1170 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002419986.1 1182489 R 440085 CDS YP_002419987.1 218529171 7117865 1184167..1185672 1 NC_011757.1 TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: mex:Mext_1044 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 1185672 7117865 Mchl_1171 Methylobacterium extorquens CM4 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_002419987.1 1184167 D 440085 CDS YP_002419988.1 218529172 7117866 complement(1185676..1186269) 1 NC_011757.1 KEGG: mex:Mext_1045 Fe2+/Zn2+ uptake regulation protein-like protein; Fe2+/Zn2+ uptake regulation protein-like protein 1186269 7117866 Mchl_1172 Methylobacterium extorquens CM4 Fe2+/Zn2+ uptake regulation protein-like protein YP_002419988.1 1185676 R 440085 CDS YP_002419989.1 218529173 7117867 1186489..1186620 1 NC_011757.1 KEGG: mpo:Mpop_0976 hypothetical protein; hypothetical protein 1186620 7117867 Mchl_1173 Methylobacterium extorquens CM4 hypothetical protein YP_002419989.1 1186489 D 440085 CDS YP_002419990.1 218529174 7117868 1186617..1187516 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1046 ABC transporter; ABC transporter 1187516 7117868 Mchl_1174 Methylobacterium extorquens CM4 ABC transporter YP_002419990.1 1186617 D 440085 CDS YP_002419991.1 218529175 7117869 1187513..1188400 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_1047 ABC transporter; ABC transporter 1188400 7117869 Mchl_1175 Methylobacterium extorquens CM4 ABC transporter YP_002419991.1 1187513 D 440085 CDS YP_002419992.1 218529176 7117870 1188646..1188750 1 NC_011757.1 KEGG: mpo:Mpop_0996 hypothetical protein; hypothetical protein 1188750 7117870 Mchl_1176 Methylobacterium extorquens CM4 hypothetical protein YP_002419992.1 1188646 D 440085 CDS YP_002419993.1 218529177 7117871 1188956..1192477 1 NC_011757.1 KEGG: mex:Mext_1048 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III subunit alpha; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein; DNA polymerase III subunit alpha 1192477 7117871 Mchl_1177 Methylobacterium extorquens CM4 DNA polymerase III subunit alpha YP_002419993.1 1188956 D 440085 CDS YP_002419994.1 218529178 7117872 1192799..1193584 1 NC_011757.1 KEGG: mex:Mext_1049 hypothetical protein; hypothetical protein 1193584 7117872 Mchl_1178 Methylobacterium extorquens CM4 hypothetical protein YP_002419994.1 1192799 D 440085 CDS YP_002419995.1 218529179 7117873 complement(1193699..1194394) 1 NC_011757.1 PFAM: cation transport protein ChaC; AIG2 family protein; KEGG: mex:Mext_1050 cation transport protein ChaC; cation transport protein ChaC 1194394 7117873 Mchl_1179 Methylobacterium extorquens CM4 cation transport protein ChaC YP_002419995.1 1193699 R 440085 CDS YP_002419996.1 218529180 7117874 complement(1194648..1195040) 1 NC_011757.1 KEGG: mpo:Mpop_0992 hypothetical protein; hypothetical protein 1195040 7117874 Mchl_1180 Methylobacterium extorquens CM4 hypothetical protein YP_002419996.1 1194648 R 440085 CDS YP_002419997.1 218529181 7117875 1195169..1195909 1 NC_011757.1 TIGRFAM: DNA repair protein RecO; PFAM: recombination protein O RecO; KEGG: mex:Mext_1051 DNA repair protein RecO; DNA repair protein RecO 1195909 7117875 Mchl_1181 Methylobacterium extorquens CM4 DNA repair protein RecO YP_002419997.1 1195169 D 440085 CDS YP_002419998.1 218529182 7117876 1196031..1198277 1 NC_011757.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1198277 7117876 Mchl_1182 Methylobacterium extorquens CM4 DNA topoisomerase IV subunit A YP_002419998.1 1196031 D 440085 CDS YP_002419999.1 218529183 7117877 complement(1198354..1198629) 1 NC_011757.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1198629 infA 7117877 infA Methylobacterium extorquens CM4 translation initiation factor IF-1 YP_002419999.1 1198354 R 440085 CDS YP_002420000.1 218529184 7117878 complement(1198947..1200059) 1 NC_011757.1 PFAM: extracellular ligand-binding receptor; KEGG: mex:Mext_1054 extracellular ligand-binding receptor; extracellular ligand-binding receptor 1200059 7117878 Mchl_1184 Methylobacterium extorquens CM4 extracellular ligand-binding receptor YP_002420000.1 1198947 R 440085 CDS YP_002420001.1 218529185 7117879 1200229..1200552 1 NC_011757.1 PFAM: protein of unknown function DUF182; KEGG: mpo:Mpop_0987 protein of unknown function DUF182; hypothetical protein 1200552 7117879 Mchl_1185 Methylobacterium extorquens CM4 hypothetical protein YP_002420001.1 1200229 D 440085 CDS YP_002420002.1 218529186 7117880 1200619..1201347 1 NC_011757.1 KEGG: mex:Mext_1056 xanthine dehydrogenase accessory factor; xanthine dehydrogenase accessory factor 1201347 7117880 Mchl_1186 Methylobacterium extorquens CM4 xanthine dehydrogenase accessory factor YP_002420002.1 1200619 D 440085 CDS YP_002420003.1 218529187 7117881 1201352..1202362 1 NC_011757.1 PFAM: molybdopterin binding domain; KEGG: mex:Mext_1057 molybdopterin binding domain-containing protein; molybdopterin binding domain 1202362 7117881 Mchl_1187 Methylobacterium extorquens CM4 molybdopterin binding domain YP_002420003.1 1201352 D 440085 CDS YP_002420004.1 218529188 7117882 1202349..1202942 1 NC_011757.1 KEGG: mex:Mext_1058 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 1202942 7117882 Mchl_1188 Methylobacterium extorquens CM4 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_002420004.1 1202349 D 440085 CDS YP_002420005.1 218529189 7117883 complement(1202950..1203111) 1 NC_011757.1 KEGG: mex:Mext_1059 hypothetical protein; hypothetical protein 1203111 7117883 Mchl_1189 Methylobacterium extorquens CM4 hypothetical protein YP_002420005.1 1202950 R 440085 CDS YP_002420006.1 218529190 7117884 complement(1203316..1204182) 1 NC_011757.1 PFAM: formyl transferase; KEGG: mex:Mext_1060 formyl transferase domain-containing protein; formyl transferase 1204182 7117884 Mchl_1190 Methylobacterium extorquens CM4 formyl transferase YP_002420006.1 1203316 R 440085 CDS YP_002420007.1 218529191 7117885 1204347..1205081 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1061 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1205081 7117885 Mchl_1191 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002420007.1 1204347 D 440085 CDS YP_002420008.1 218529192 7117886 complement(1205140..1205901) 1 NC_011757.1 KEGG: mex:Mext_1062 hypothetical protein; hypothetical protein 1205901 7117886 Mchl_1192 Methylobacterium extorquens CM4 hypothetical protein YP_002420008.1 1205140 R 440085 CDS YP_002420009.1 218529193 7117887 1206153..1206785 1 NC_011757.1 PFAM: Exopolysaccharide synthesis ExoD; KEGG: mpo:Mpop_0979 exopolysaccharide synthesis ExoD; Exopolysaccharide synthesis ExoD 1206785 7117887 Mchl_1193 Methylobacterium extorquens CM4 Exopolysaccharide synthesis ExoD YP_002420009.1 1206153 D 440085 CDS YP_002420010.1 218529194 7117888 complement(1206990..1207700) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1064 ABC transporter; ABC transporter 1207700 7117888 Mchl_1194 Methylobacterium extorquens CM4 ABC transporter YP_002420010.1 1206990 R 440085 CDS YP_002420011.1 218529195 7117889 complement(1207716..1209035) 1 NC_011757.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: mex:Mext_1065 LolC/E family lipoprotein releasing system, transmembrane protein; lipoprotein releasing system, transmembrane protein, LolC/E family 1209035 7117889 Mchl_1195 Methylobacterium extorquens CM4 lipoprotein releasing system, transmembrane protein, LolC/E family YP_002420011.1 1207716 R 440085 CDS YP_002420012.1 218529196 7117890 complement(1209048..1210373) 1 NC_011757.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1210373 7117890 Mchl_1196 Methylobacterium extorquens CM4 prolyl-tRNA synthetase YP_002420012.1 1209048 R 440085 CDS YP_002420013.1 218529197 7117891 complement(1210849..1211190) 1 NC_011757.1 PFAM: protein of unknown function DUF1467; KEGG: mex:Mext_1068 hypothetical protein; hypothetical protein 1211190 7117891 Mchl_1197 Methylobacterium extorquens CM4 hypothetical protein YP_002420013.1 1210849 R 440085 CDS YP_002420014.1 218529198 7117892 complement(1211256..1211660) 1 NC_011757.1 KEGG: mex:Mext_1069 methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; methylmalonyl-CoA epimerase 1211660 7117892 Mchl_1198 Methylobacterium extorquens CM4 methylmalonyl-CoA epimerase YP_002420014.1 1211256 R 440085 CDS YP_002420015.1 218529199 7117893 complement(1211811..1213484) 1 NC_011757.1 PFAM: beta-lactamase; RNA-metabolising metallo-beta-lactamase; KEGG: mex:Mext_1070 beta-lactamase domain-containing protein; beta-lactamase 1213484 7117893 Mchl_1199 Methylobacterium extorquens CM4 beta-lactamase YP_002420015.1 1211811 R 440085 CDS YP_002420016.1 218529200 7117894 complement(1213504..1214343) 1 NC_011757.1 TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: mex:Mext_1071 biotin--acetyl-CoA-carboxylase ligase; biotin/acetyl-CoA-carboxylase ligase 1214343 7117894 Mchl_1200 Methylobacterium extorquens CM4 biotin/acetyl-CoA-carboxylase ligase YP_002420016.1 1213504 R 440085 CDS YP_002420017.1 218529201 7117895 complement(1214349..1215788) 1 NC_011757.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: mex:Mext_1072 proton-translocating NADH-quinone oxidoreductase, chain N; proton-translocating NADH-quinone oxidoreductase subunit N 1215788 7117895 Mchl_1201 Methylobacterium extorquens CM4 proton-translocating NADH-quinone oxidoreductase subunit N YP_002420017.1 1214349 R 440085 CDS YP_002420018.1 218529202 7117896 complement(1215785..1217368) 1 NC_011757.1 KEGG: mex:Mext_1073 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); proton-translocating NADH-quinone oxidoreductase subunit M 1217368 7117896 Mchl_1202 Methylobacterium extorquens CM4 proton-translocating NADH-quinone oxidoreductase subunit M YP_002420018.1 1215785 R 440085 CDS YP_002420019.1 218529203 7117897 complement(1217368..1219479) 1 NC_011757.1 KEGG: mex:Mext_1074 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); proton-translocating NADH-quinone oxidoreductase subunit L 1219479 7117897 Mchl_1203 Methylobacterium extorquens CM4 proton-translocating NADH-quinone oxidoreductase subunit L YP_002420019.1 1217368 R 440085 CDS YP_002420020.1 218529204 7117898 complement(1219538..1219843) 1 NC_011757.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: mpo:Mpop_1009 NADH-ubiquinone oxidoreductase chain 4L; NADH-ubiquinone oxidoreductase chain 4L 1219843 7117898 Mchl_1204 Methylobacterium extorquens CM4 NADH-ubiquinone oxidoreductase chain 4L YP_002420020.1 1219538 R 440085 CDS YP_002420021.1 218529205 7117899 complement(1219849..1220469) 1 NC_011757.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: mex:Mext_1076 NADH-ubiquinone/plastoquinone oxidoreductase chain 6; NADH-ubiquinone/plastoquinone oxidoreductase chain 6 1220469 7117899 Mchl_1205 Methylobacterium extorquens CM4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_002420021.1 1219849 R 440085 CDS YP_002420022.1 218529206 7117900 complement(1220679..1221167) 1 NC_011757.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1221167 7117900 Mchl_1206 Methylobacterium extorquens CM4 NADH dehydrogenase subunit I YP_002420022.1 1220679 R 440085 CDS YP_002420023.1 218529207 7117901 complement(1221252..1222274) 1 NC_011757.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1222274 7117901 Mchl_1207 Methylobacterium extorquens CM4 NADH dehydrogenase subunit H YP_002420023.1 1221252 R 440085 CDS YP_002420024.1 218529208 7117902 complement(1222287..1224353) 1 NC_011757.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 1224353 7117902 Mchl_1208 Methylobacterium extorquens CM4 NADH dehydrogenase subunit G YP_002420024.1 1222287 R 440085 CDS YP_002420025.1 218529209 7117903 complement(1224388..1225689) 1 NC_011757.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 1225689 7117903 Mchl_1209 Methylobacterium extorquens CM4 NADH dehydrogenase I subunit F YP_002420025.1 1224388 R 440085 CDS YP_002420026.1 218529210 7117904 complement(1225700..1226938) 1 NC_011757.1 KEGG: mex:Mext_1081 NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; NADH-quinone oxidoreductase subunit E 1226938 7117904 Mchl_1210 Methylobacterium extorquens CM4 NADH-quinone oxidoreductase subunit E YP_002420026.1 1225700 R 440085 CDS YP_002420027.1 218529211 7117905 complement(1226957..1228147) 1 NC_011757.1 KEGG: mex:Mext_1082 NADH dehydrogenase I, D subunit; TIGRFAM: NADH dehydrogenase I, D subunit; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase I subunit D 1228147 7117905 Mchl_1211 Methylobacterium extorquens CM4 NADH dehydrogenase I subunit D YP_002420027.1 1226957 R 440085 CDS YP_002420028.1 218529212 7117906 complement(1228159..1228818) 1 NC_011757.1 KEGG: mex:Mext_1083 NADH (or F420H2) dehydrogenase, subunit C; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH (or F420H2) dehydrogenase subunit C 1228818 7117906 Mchl_1212 Methylobacterium extorquens CM4 NADH (or F420H2) dehydrogenase subunit C YP_002420028.1 1228159 R 440085 CDS YP_002420029.1 218529213 7117907 complement(1228830..1229417) 1 NC_011757.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1229417 7117907 Mchl_1213 Methylobacterium extorquens CM4 NADH dehydrogenase subunit B YP_002420029.1 1228830 R 440085 CDS YP_002420030.1 218529214 7117908 complement(1229470..1229835) 1 NC_011757.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; KEGG: mpo:Mpop_1019 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NADH-ubiquinone/plastoquinone oxidoreductase chain 3 1229835 7117908 Mchl_1214 Methylobacterium extorquens CM4 NADH-ubiquinone/plastoquinone oxidoreductase chain 3 YP_002420030.1 1229470 R 440085 CDS YP_002420031.1 218529215 7117910 1230667..1231155 1 NC_011757.1 PFAM: SCP-like extracellular; KEGG: mex:Mext_1086 SCP-like extracellular; SCP-like extracellular 1231155 7117910 Mchl_1215 Methylobacterium extorquens CM4 SCP-like extracellular YP_002420031.1 1230667 D 440085 CDS YP_002420032.1 218529216 7117911 complement(1231201..1231641) 1 NC_011757.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: mex:Mext_1087 pseudoazurin; pseudoazurin 1231641 7117911 Mchl_1216 Methylobacterium extorquens CM4 pseudoazurin YP_002420032.1 1231201 R 440085 CDS YP_002420033.1 218529217 7117912 1231937..1235410 1 NC_011757.1 TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain oligomerisation; carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: mex:Mext_1088 carbamoyl-phosphate synthase, large subunit; carbamoyl-phosphate synthase, large subunit 1235410 7117912 Mchl_1217 Methylobacterium extorquens CM4 carbamoyl-phosphate synthase, large subunit YP_002420033.1 1231937 D 440085 CDS YP_002420034.1 218529218 7117913 1235541..1236023 1 NC_011757.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1236023 greA 7117913 greA Methylobacterium extorquens CM4 transcription elongation factor GreA YP_002420034.1 1235541 D 440085 CDS YP_002420035.1 218529219 7117914 1236029..1236529 1 NC_011757.1 KEGG: mex:Mext_1090 hypothetical protein; hypothetical protein 1236529 7117914 Mchl_1219 Methylobacterium extorquens CM4 hypothetical protein YP_002420035.1 1236029 D 440085 CDS YP_002420036.1 218529220 7117915 1236540..1237664 1 NC_011757.1 PFAM: protein of unknown function DUF1022; KEGG: mex:Mext_1091 hypothetical protein; hypothetical protein 1237664 7117915 Mchl_1220 Methylobacterium extorquens CM4 hypothetical protein YP_002420036.1 1236540 D 440085 CDS YP_002420037.1 218529221 7117916 1237815..1238789 1 NC_011757.1 KEGG: mex:Mext_1092 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase 1238789 7117916 Mchl_1221 Methylobacterium extorquens CM4 thioredoxin reductase YP_002420037.1 1237815 D 440085 CDS YP_002420038.1 218529222 7117917 1239130..1240020 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1093 LysR substrate-binding; LysR family transcriptional regulator 1240020 7117917 Mchl_1222 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420038.1 1239130 D 440085 CDS YP_002420039.1 218529223 7117918 1240137..1240592 1 NC_011757.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1240592 7117918 Mchl_1223 Methylobacterium extorquens CM4 3-dehydroquinate dehydratase YP_002420039.1 1240137 D 440085 CDS YP_002420040.1 218529224 7117919 1240611..1241081 1 NC_011757.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: mex:Mext_1095 acetyl-CoA carboxylase, biotin carboxyl carrier protein; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1241081 7117919 Mchl_1224 Methylobacterium extorquens CM4 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_002420040.1 1240611 D 440085 CDS YP_002420041.1 218529225 7117920 1241092..1242459 1 NC_011757.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: mex:Mext_1096 acetyl-CoA carboxylase, biotin carboxylase; acetyl-CoA carboxylase, biotin carboxylase 1242459 7117920 Mchl_1225 Methylobacterium extorquens CM4 acetyl-CoA carboxylase, biotin carboxylase YP_002420041.1 1241092 D 440085 CDS YP_002420042.1 218529226 7117921 1242544..1243218 1 NC_011757.1 KEGG: mex:Mext_1097 leucyltransferase; TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase; PFAM: leucyl/phenylalanyl-tRNA--protein transferase; leucyl/phenylalanyl-tRNA/protein transferase 1243218 7117921 Mchl_1226 Methylobacterium extorquens CM4 leucyl/phenylalanyl-tRNA/protein transferase YP_002420042.1 1242544 D 440085 CDS YP_002420043.1 218529227 7117922 complement(1243285..1243905) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1098 regulatory protein TetR; TetR family transcriptional regulator 1243905 7117922 Mchl_1227 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420043.1 1243285 R 440085 CDS YP_002420044.1 218529228 7117923 1243953..1244432 1 NC_011757.1 KEGG: mex:Mext_1099 hypothetical protein; hypothetical protein 1244432 7117923 Mchl_1228 Methylobacterium extorquens CM4 hypothetical protein YP_002420044.1 1243953 D 440085 CDS YP_002420045.1 218529229 7117924 complement(1244532..1245191) 1 NC_011757.1 KEGG: mex:Mext_1100 hypothetical protein; hypothetical protein 1245191 7117924 Mchl_1229 Methylobacterium extorquens CM4 hypothetical protein YP_002420045.1 1244532 R 440085 CDS YP_002420046.1 218529230 7117925 complement(1245369..1245785) 1 NC_011757.1 PFAM: NADH:ubiquinone oxidoreductase 17.2 kD subunit; KEGG: mex:Mext_1101 NADH:ubiquinone oxidoreductase 17.2 kD subunit; NADH:ubiquinone oxidoreductase 17.2 kD subunit 1245785 7117925 Mchl_1230 Methylobacterium extorquens CM4 NADH:ubiquinone oxidoreductase 17.2 kD subunit YP_002420046.1 1245369 R 440085 CDS YP_002420047.1 218529231 7117926 1246305..1250036 1 NC_011757.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1250036 7117926 Mchl_1231 Methylobacterium extorquens CM4 ribonucleotide-diphosphate reductase subunit alpha YP_002420047.1 1246305 D 440085 CDS YP_002420048.1 218529232 7117927 1250690..1252600 1 NC_011757.1 PFAM: K potassium transporter; KEGG: mpo:Mpop_0308 K potassium transporter; K potassium transporter 1252600 7117927 Mchl_1232 Methylobacterium extorquens CM4 K potassium transporter YP_002420048.1 1250690 D 440085 CDS YP_002420049.1 218529233 7117928 complement(1252659..1253195) 1 NC_011757.1 KEGG: mex:Mext_1123 hypothetical protein; hypothetical protein 1253195 7117928 Mchl_1233 Methylobacterium extorquens CM4 hypothetical protein YP_002420049.1 1252659 R 440085 CDS YP_002420050.1 218529234 7117930 complement(1253486..1254478) 1 NC_011757.1 KEGG: mex:Mext_1125 hypothetical protein; hypothetical protein 1254478 7117930 Mchl_1235 Methylobacterium extorquens CM4 hypothetical protein YP_002420050.1 1253486 R 440085 CDS YP_002420051.1 218529235 7117932 1255275..1256327 1 NC_011757.1 PFAM: Platelet-activating factor acetylhydrolase plasma/intracellular isoform II; KEGG: mex:Mext_1126 platelet-activating factor acetylhydrolase plasma/intracellular isoform II; Platelet-activating factor acetylhydrolase plasma/intracellular isoform II 1256327 7117932 Mchl_1237 Methylobacterium extorquens CM4 Platelet-activating factor acetylhydrolase plasma/intracellular isoform II YP_002420051.1 1255275 D 440085 CDS YP_002420052.1 218529236 7117933 1256363..1257496 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_1127 metallophosphoesterase; metallophosphoesterase 1257496 7117933 Mchl_1238 Methylobacterium extorquens CM4 metallophosphoesterase YP_002420052.1 1256363 D 440085 CDS YP_002420053.1 218529237 7117934 complement(1257898..1258257) 1 NC_011757.1 KEGG: mex:Mext_1128 hypothetical protein; hypothetical protein 1258257 7117934 Mchl_1239 Methylobacterium extorquens CM4 hypothetical protein YP_002420053.1 1257898 R 440085 CDS YP_002420054.1 218529238 7117935 1258465..1258695 1 NC_011757.1 hypothetical protein 1258695 7117935 Mchl_1240 Methylobacterium extorquens CM4 hypothetical protein YP_002420054.1 1258465 D 440085 CDS YP_002420055.1 218529239 7117936 complement(1259059..1259556) 1 NC_011757.1 PFAM: protein of unknown function DUF892; KEGG: mex:Mext_1129 hypothetical protein; hypothetical protein 1259556 7117936 Mchl_1241 Methylobacterium extorquens CM4 hypothetical protein YP_002420055.1 1259059 R 440085 CDS YP_002420056.1 218529240 7117937 complement(1259898..1261382) 1 NC_011757.1 KEGG: mex:Mext_1130 hypothetical protein; hypothetical protein 1261382 7117937 Mchl_1242 Methylobacterium extorquens CM4 hypothetical protein YP_002420056.1 1259898 R 440085 CDS YP_002420057.1 218529241 7117938 1261849..1262688 1 NC_011757.1 PFAM: formate/nitrite transporter; KEGG: mex:Mext_1131 formate/nitrite transporter; formate/nitrite transporter 1262688 7117938 Mchl_1243 Methylobacterium extorquens CM4 formate/nitrite transporter YP_002420057.1 1261849 D 440085 CDS YP_002420058.1 218529242 7117939 1262756..1264471 1 NC_011757.1 PFAM: tyrosine protein kinase; aminoglycoside phosphotransferase; protein phosphatase 2C-like; serine/threonine protein kinase-related; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: mex:Mext_1132 protein kinase; serine/threonine protein kinase 1264471 7117939 Mchl_1244 Methylobacterium extorquens CM4 serine/threonine protein kinase YP_002420058.1 1262756 D 440085 CDS YP_002420059.1 218529243 7117940 complement(1265355..1267373) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_1133 cellulose synthase (UDP-forming); cellulose synthase 1267373 7117940 Mchl_1245 Methylobacterium extorquens CM4 cellulose synthase YP_002420059.1 1265355 R 440085 CDS YP_002420060.1 218529244 7117941 complement(1267355..1268590) 1 NC_011757.1 KEGG: mex:Mext_1134 hypothetical protein; hypothetical protein 1268590 7117941 Mchl_1246 Methylobacterium extorquens CM4 hypothetical protein YP_002420060.1 1267355 R 440085 CDS YP_002420061.1 218529245 7117942 1268965..1269171 1 NC_011757.1 KEGG: mpo:Mpop_3719 hypothetical protein; hypothetical protein 1269171 7117942 Mchl_1247 Methylobacterium extorquens CM4 hypothetical protein YP_002420061.1 1268965 D 440085 CDS YP_002420062.1 218529246 7115429 complement(1269528..1269893) 1 NC_011757.1 PFAM: PRC-barrel domain protein; KEGG: mex:Mext_1105 PRC-barrel domain-containing protein; PRC-barrel domain-containing protein 1269893 7115429 Mchl_1248 Methylobacterium extorquens CM4 PRC-barrel domain-containing protein YP_002420062.1 1269528 R 440085 CDS YP_002420063.1 218529247 7115512 1271105..1271854 1 NC_011757.1 PFAM: ion transporter; ion transport 2 domain protein; KEGG: mex:Mext_1106 ion transport 2 domain-containing protein; ion transport 2 domain-containing protein 1271854 7115512 Mchl_1249 Methylobacterium extorquens CM4 ion transport 2 domain-containing protein YP_002420063.1 1271105 D 440085 CDS YP_002420064.1 218529248 7115513 complement(1271937..1272794) 1 NC_011757.1 KEGG: mex:Mext_1107 hypothetical protein; hypothetical protein 1272794 7115513 Mchl_1250 Methylobacterium extorquens CM4 hypothetical protein YP_002420064.1 1271937 R 440085 CDS YP_002420065.1 218529249 7115514 1272906..1273433 1 NC_011757.1 PFAM: protein of unknown function DUF421; KEGG: mex:Mext_1108 hypothetical protein; hypothetical protein 1273433 7115514 Mchl_1251 Methylobacterium extorquens CM4 hypothetical protein YP_002420065.1 1272906 D 440085 CDS YP_002420066.1 218529250 7115515 complement(1273796..1274182) 1 NC_011757.1 PFAM: endoribonuclease L-PSP; KEGG: mex:Mext_1109 endoribonuclease L-PSP; endoribonuclease L-PSP 1274182 7115515 Mchl_1252 Methylobacterium extorquens CM4 endoribonuclease L-PSP YP_002420066.1 1273796 R 440085 CDS YP_002420067.1 218529251 7115516 complement(1274281..1275381) 1 NC_011757.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: mex:Mext_1110 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 1275381 7115516 Mchl_1253 Methylobacterium extorquens CM4 NADH:flavin oxidoreductase/NADH oxidase YP_002420067.1 1274281 R 440085 CDS YP_002420068.1 218529252 7115517 1275487..1276410 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1111 carbonate dehydratase; LysR family transcriptional regulator 1276410 7115517 Mchl_1254 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420068.1 1275487 D 440085 CDS YP_002420069.1 218529253 7115518 1276709..1277272 1 NC_011757.1 KEGG: mex:Mext_1112 hypothetical protein; hypothetical protein 1277272 7115518 Mchl_1255 Methylobacterium extorquens CM4 hypothetical protein YP_002420069.1 1276709 D 440085 CDS YP_002420070.1 218529254 7115519 1277409..1278011 1 NC_011757.1 KEGG: hypothetical protein; hypothetical protein 1278011 7115519 Mchl_1256 Methylobacterium extorquens CM4 hypothetical protein YP_002420070.1 1277409 D 440085 CDS YP_002420071.1 218529255 7115520 1278134..1278616 1 NC_011757.1 KEGG: mex:Mext_1113 hypothetical protein; hypothetical protein 1278616 7115520 Mchl_1257 Methylobacterium extorquens CM4 hypothetical protein YP_002420071.1 1278134 D 440085 CDS YP_002420072.1 218529256 7115521 complement(1278646..1278744) 1 NC_011757.1 KEGG: mxa:MXAN_3681 hypothetical protein; hypothetical protein 1278744 7115521 Mchl_1258 Methylobacterium extorquens CM4 hypothetical protein YP_002420072.1 1278646 R 440085 CDS YP_002420073.1 218529257 7115522 complement(1279567..1280469) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mrd:Mrad2831_4570 LysR family transcriptional regulator; LysR family transcriptional regulator 1280469 7115522 Mchl_1259 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420073.1 1279567 R 440085 CDS YP_002420074.1 218529258 7115523 1280587..1281543 1 NC_011757.1 PFAM: NMT1/THI5 like domain protein; KEGG: mrd:Mrad2831_4569 NMT1/THI5-like domain-containing protein; NMT1/THI5 like domain-containing protein 1281543 7115523 Mchl_1260 Methylobacterium extorquens CM4 NMT1/THI5 like domain-containing protein YP_002420074.1 1280587 D 440085 CDS YP_002420075.1 218529259 7115524 1281540..1282421 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mrd:Mrad2831_4568 binding-protein-dependent transporters inner membrane component; binding-protein-dependent transporters inner membrane component 1282421 7115524 Mchl_1261 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420075.1 1281540 D 440085 CDS YP_002420076.1 218529260 7115525 1282414..1283193 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mrd:Mrad2831_4567 ABC transporter; ABC transporter 1283193 7115525 Mchl_1262 Methylobacterium extorquens CM4 ABC transporter YP_002420076.1 1282414 D 440085 CDS YP_002420077.1 218529261 7115526 1283193..1284023 1 NC_011757.1 KEGG: mpo:Mpop_3788 hypothetical protein; hypothetical protein 1284023 7115526 Mchl_1263 Methylobacterium extorquens CM4 hypothetical protein YP_002420077.1 1283193 D 440085 CDS YP_002420078.1 218529262 7115527 1284020..1285897 1 NC_011757.1 catalyzes the hydrolysis of allophanate; allophanate hydrolase 1285897 7115527 Mchl_1264 Methylobacterium extorquens CM4 allophanate hydrolase YP_002420078.1 1284020 D 440085 CDS YP_002420079.1 218529263 7115528 complement(1286156..1287199) 1 NC_011757.1 PFAM: ribonuclease BN; KEGG: mex:Mext_1115 ribonuclease BN; ribonuclease BN 1287199 7115528 Mchl_1265 Methylobacterium extorquens CM4 ribonuclease BN YP_002420079.1 1286156 R 440085 CDS YP_002420080.1 218529264 7115529 1287410..1288462 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: mex:Mext_1116 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 1288462 7115529 Mchl_1266 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002420080.1 1287410 D 440085 CDS YP_002420081.1 218529265 7115530 complement(1288637..1290139) 1 NC_011757.1 KEGG: mex:Mext_1117 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 1290139 7115530 Mchl_1267 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002420081.1 1288637 R 440085 CDS YP_002420082.1 218529266 7115531 complement(1290443..1291171) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1118 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1291171 7115531 Mchl_1268 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002420082.1 1290443 R 440085 CDS YP_002420083.1 218529267 7115532 complement(1291168..1291803) 1 NC_011757.1 PFAM: protein of unknown function DUF938; KEGG: mex:Mext_1119 hypothetical protein; hypothetical protein 1291803 7115532 Mchl_1269 Methylobacterium extorquens CM4 hypothetical protein YP_002420083.1 1291168 R 440085 CDS YP_002420084.1 218529268 7115533 complement(1292076..1292729) 1 NC_011757.1 KEGG: mex:Mext_1120 hypothetical protein; hypothetical protein 1292729 7115533 Mchl_1270 Methylobacterium extorquens CM4 hypothetical protein YP_002420084.1 1292076 R 440085 CDS YP_002420085.1 218529269 7115535 1293941..1294306 1 NC_011757.1 KEGG: mex:Mext_1135 hypothetical protein; hypothetical protein 1294306 7115535 Mchl_1272 Methylobacterium extorquens CM4 hypothetical protein YP_002420085.1 1293941 D 440085 CDS YP_002420086.1 218529270 7115536 1294436..1295317 1 NC_011757.1 KEGG: met:M446_1199 hypothetical protein; hypothetical protein 1295317 7115536 Mchl_1273 Methylobacterium extorquens CM4 hypothetical protein YP_002420086.1 1294436 D 440085 CDS YP_002420087.1 218529271 7115537 complement(1295544..1296590) 1 NC_011757.1 KEGG: mrd:Mrad2831_0784 adenylate/guanylate cyclase; adenylate/guanylate cyclase 1296590 7115537 Mchl_1274 Methylobacterium extorquens CM4 adenylate/guanylate cyclase YP_002420087.1 1295544 R 440085 CDS YP_002420088.1 218529272 7115538 complement(1296985..1297425) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_0032 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 1297425 7115538 Mchl_1275 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002420088.1 1296985 R 440085 CDS YP_002420089.1 218529273 7115539 complement(1297784..1298164) 1 NC_011757.1 KEGG: mex:Mext_0033 hypothetical protein; hypothetical protein 1298164 7115539 Mchl_1276 Methylobacterium extorquens CM4 hypothetical protein YP_002420089.1 1297784 R 440085 CDS YP_002420090.1 218529274 7115540 1298341..1299441 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_0034 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 1299441 7115540 Mchl_1277 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420090.1 1298341 D 440085 CDS YP_002420091.1 218529275 7115541 1300026..1301033 1 NC_011757.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_0035 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 1301033 7115541 Mchl_1278 Methylobacterium extorquens CM4 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_002420091.1 1300026 D 440085 CDS YP_002420092.1 218529276 7115542 1301037..1303409 1 NC_011757.1 PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: mex:Mext_0036 kojibiose phosphorylase; Kojibiose phosphorylase 1303409 7115542 Mchl_1279 Methylobacterium extorquens CM4 Kojibiose phosphorylase YP_002420092.1 1301037 D 440085 CDS YP_002420093.1 218529277 7115543 1303572..1305167 1 NC_011757.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; KEGG: mex:Mext_0037 YidE/YbjL duplication; hypothetical protein 1305167 7115543 Mchl_1280 Methylobacterium extorquens CM4 hypothetical protein YP_002420093.1 1303572 D 440085 CDS YP_002420094.1 218529278 7115544 complement(1305462..1307747) 1 NC_011757.1 PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: mex:Mext_0038 kojibiose phosphorylase; Kojibiose phosphorylase 1307747 7115544 Mchl_1281 Methylobacterium extorquens CM4 Kojibiose phosphorylase YP_002420094.1 1305462 R 440085 CDS YP_002420095.1 218529279 7115545 complement(1307740..1308468) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: mex:Mext_0039 HAD family hydrolase; HAD-superfamily hydrolase 1308468 7115545 Mchl_1282 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002420095.1 1307740 R 440085 CDS YP_002420096.1 218529280 7115546 complement(1308499..1310934) 1 NC_011757.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mex:Mext_0040 phosphoketolase; phosphoketolase 1310934 7115546 Mchl_1283 Methylobacterium extorquens CM4 phosphoketolase YP_002420096.1 1308499 R 440085 CDS YP_002420097.1 218529281 7115547 complement(1311076..1311543) 1 NC_011757.1 KEGG: mex:Mext_0041 hypothetical protein; hypothetical protein 1311543 7115547 Mchl_1284 Methylobacterium extorquens CM4 hypothetical protein YP_002420097.1 1311076 R 440085 CDS YP_002420098.1 218529282 7115548 complement(1311738..1311971) 1 NC_011757.1 KEGG: mex:Mext_0042 hypothetical protein; hypothetical protein 1311971 7115548 Mchl_1285 Methylobacterium extorquens CM4 hypothetical protein YP_002420098.1 1311738 R 440085 CDS YP_002420099.1 218529283 7115549 complement(1312230..1313312) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_0043 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 1313312 7115549 Mchl_1286 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420099.1 1312230 R 440085 CDS YP_002420100.1 218529284 7115550 complement(1313856..1314284) 1 NC_011757.1 KEGG: met:M446_1577 hypothetical protein; hypothetical protein 1314284 7115550 Mchl_1287 Methylobacterium extorquens CM4 hypothetical protein YP_002420100.1 1313856 R 440085 CDS YP_002420101.1 218529285 7115551 complement(1314305..1315426) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_0045 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 1315426 7115551 Mchl_1288 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420101.1 1314305 R 440085 CDS YP_002420102.1 218529286 7115552 1316189..1316620 1 NC_011757.1 KEGG: mex:Mext_0047 hypothetical protein; hypothetical protein 1316620 7115552 Mchl_1289 Methylobacterium extorquens CM4 hypothetical protein YP_002420102.1 1316189 D 440085 CDS YP_002420103.1 218529287 7115553 1316859..1317362 1 NC_011757.1 KEGG: mex:Mext_0048 hypothetical protein; hypothetical protein 1317362 7115553 Mchl_1290 Methylobacterium extorquens CM4 hypothetical protein YP_002420103.1 1316859 D 440085 CDS YP_002420104.1 218529288 7115554 complement(1317566..1319236) 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: mex:Mext_0049 sulfate transporter; sulfate transporter 1319236 7115554 Mchl_1291 Methylobacterium extorquens CM4 sulfate transporter YP_002420104.1 1317566 R 440085 CDS YP_002420105.1 218529289 7115555 1319750..1320175 1 NC_011757.1 KEGG: mex:Mext_0050 hypothetical protein; hypothetical protein 1320175 7115555 Mchl_1292 Methylobacterium extorquens CM4 hypothetical protein YP_002420105.1 1319750 D 440085 CDS YP_002420106.1 218529290 7115556 complement(1320356..1320877) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_0051 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 1320877 7115556 Mchl_1293 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002420106.1 1320356 R 440085 CDS YP_002420107.1 218529291 7115557 1321310..1322284 1 NC_011757.1 PFAM: phosphate acetyl/butaryl transferase; KEGG: mex:Mext_0052 phosphate butyryltransferase; phosphate acetyltransferase 1322284 7115557 Mchl_1294 Methylobacterium extorquens CM4 phosphate acetyltransferase YP_002420107.1 1321310 D 440085 CDS YP_002420108.1 218529292 7115558 1322288..1323496 1 NC_011757.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: mex:Mext_0053 acetate kinase; acetate kinase 1323496 7115558 Mchl_1295 Methylobacterium extorquens CM4 acetate kinase YP_002420108.1 1322288 D 440085 CDS YP_002420109.1 218529293 7115559 1323513..1324007 1 NC_011757.1 KEGG: mex:Mext_0054 hypothetical protein; hypothetical protein 1324007 7115559 Mchl_1296 Methylobacterium extorquens CM4 hypothetical protein YP_002420109.1 1323513 D 440085 CDS YP_002420110.1 218529294 7115560 complement(1324382..1325224) 1 NC_011757.1 PFAM: protein of unknown function DUF344; KEGG: mex:Mext_1138 hypothetical protein; hypothetical protein 1325224 7115560 Mchl_1297 Methylobacterium extorquens CM4 hypothetical protein YP_002420110.1 1324382 R 440085 CDS YP_002420111.1 218529295 7115561 complement(1325266..1328457) 1 NC_011757.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_1139 hydrophobe/amphiphile efflux-1 (HAE1) family protein; hydrophobe/amphiphile efflux-1 (HAE1) family transporter 1328457 7115561 Mchl_1298 Methylobacterium extorquens CM4 hydrophobe/amphiphile efflux-1 (HAE1) family transporter YP_002420111.1 1325266 R 440085 CDS YP_002420112.1 218529296 7115562 complement(1328463..1329587) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_1140 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 1329587 7115562 Mchl_1299 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002420112.1 1328463 R 440085 CDS YP_002420113.1 218529297 7115564 complement(1330046..1330495) 1 NC_011757.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: mex:Mext_1142 protein of unknown function DUF395 YeeE/YedE; hypothetical protein 1330495 7115564 Mchl_1301 Methylobacterium extorquens CM4 hypothetical protein YP_002420113.1 1330046 R 440085 CDS YP_002420114.1 218529298 7115565 complement(1330499..1330924) 1 NC_011757.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: mex:Mext_1143 protein of unknown function DUF395 YeeE/YedE; hypothetical protein 1330924 7115565 Mchl_1302 Methylobacterium extorquens CM4 hypothetical protein YP_002420114.1 1330499 R 440085 CDS YP_002420115.1 218529299 7115566 1331347..1333287 1 NC_011757.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; E1-E2 ATPase-associated domain protein; KEGG: met:M446_3593 heavy metal translocating P-type ATPase; ATPase P 1333287 7115566 Mchl_1303 Methylobacterium extorquens CM4 ATPase P YP_002420115.1 1331347 D 440085 CDS YP_002420116.1 218529300 7115567 complement(1333395..1333733) 1 NC_011757.1 PFAM: regulatory protein ArsR; transcriptional regulator TrmB; KEGG: mex:Mext_1145 regulatory protein ArsR; TrmB family transcriptional regulator 1333733 7115567 Mchl_1304 Methylobacterium extorquens CM4 TrmB family transcriptional regulator YP_002420116.1 1333395 R 440085 CDS YP_002420117.1 218529301 7115568 complement(1334149..1335129) 1 NC_011757.1 KEGG: mpo:Mpop_4661 nitrate ABC transporter ATPase subunits C and D; TIGRFAM: nitrate ABC transporter ATPases C and D; PFAM: ABC transporter; SMART: ATPase AAA; nitrate ABC transporter ATPases C and D 1335129 7115568 Mchl_1305 Methylobacterium extorquens CM4 nitrate ABC transporter ATPases C and D YP_002420117.1 1334149 R 440085 CDS YP_002420118.1 218529302 7115569 complement(1335138..1335977) 1 NC_011757.1 TIGRFAM: nitrate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1147 nitrate ABC transporter inner membrane subunit; nitrate ABC transporter inner membrane subunit 1335977 7115569 Mchl_1306 Methylobacterium extorquens CM4 nitrate ABC transporter inner membrane subunit YP_002420118.1 1335138 R 440085 CDS YP_002420119.1 218529303 7115570 complement(1335982..1337343) 1 NC_011757.1 KEGG: mex:Mext_1148 nitrate-binding ABC transporter substrate-binding protein; nitrate-binding ABC transporter substrate-binding protein 1337343 7115570 Mchl_1307 Methylobacterium extorquens CM4 nitrate-binding ABC transporter substrate-binding protein YP_002420119.1 1335982 R 440085 CDS YP_002420120.1 218529304 7115571 complement(1337509..1338843) 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rubredoxin-type Fe(Cys)4 protein; KEGG: mex:Mext_1149 rubredoxin-type Fe(Cys)4 protein; Rubredoxin-type Fe(Cys)4 protein 1338843 7115571 Mchl_1308 Methylobacterium extorquens CM4 Rubredoxin-type Fe(Cys)4 protein YP_002420120.1 1337509 R 440085 CDS YP_002420121.1 218529305 7115572 complement(1338840..1340033) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mex:Mext_1150 acyl-CoA dehydrogenase-like protein; acyl-CoA dehydrogenase domain-containing protein 1340033 7115572 Mchl_1309 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002420121.1 1338840 R 440085 CDS YP_002420122.1 218529306 7115573 complement(1340094..1340645) 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_1151 OsmC family protein; OsmC family protein 1340645 7115573 Mchl_1310 Methylobacterium extorquens CM4 OsmC family protein YP_002420122.1 1340094 R 440085 CDS YP_002420123.1 218529307 7115574 complement(1340858..1342474) 1 NC_011757.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_1152 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 1342474 7115574 Mchl_1311 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002420123.1 1340858 R 440085 CDS YP_002420124.1 218529308 7115575 complement(1342832..1343848) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: mex:Mext_1153 ThiJ/PfpI domain-containing protein; AraC family transcriptional regulator 1343848 7115575 Mchl_1312 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420124.1 1342832 R 440085 CDS YP_002420125.1 218529309 7115576 1343899..1344603 1 NC_011757.1 PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_1154 ThiJ/PfpI domain-containing protein; ThiJ/PfpI domain-containing protein 1344603 7115576 Mchl_1313 Methylobacterium extorquens CM4 ThiJ/PfpI domain-containing protein YP_002420125.1 1343899 D 440085 CDS YP_002420126.1 218529310 7115577 complement(1344678..1346246) 1 NC_011757.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: mex:Mext_1155 SSS family solute/sodium (Na+) symporter; SSS sodium solute transporter superfamily protein 1346246 7115577 Mchl_1314 Methylobacterium extorquens CM4 SSS sodium solute transporter superfamily protein YP_002420126.1 1344678 R 440085 CDS YP_002420127.1 218529311 7115578 complement(1346257..1346553) 1 NC_011757.1 PFAM: protein of unknown function DUF485; KEGG: mex:Mext_1156 hypothetical protein; hypothetical protein 1346553 7115578 Mchl_1315 Methylobacterium extorquens CM4 hypothetical protein YP_002420127.1 1346257 R 440085 CDS YP_002420128.1 218529312 7115579 complement(1346662..1347771) 1 NC_011757.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mex:Mext_1157 nitrilase; nitrilase 1347771 7115579 Mchl_1316 Methylobacterium extorquens CM4 nitrilase YP_002420128.1 1346662 R 440085 CDS YP_002420129.1 218529313 7115580 complement(1347874..1348770) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1158 LysR substrate-binding; LysR family transcriptional regulator 1348770 7115580 Mchl_1317 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420129.1 1347874 R 440085 CDS YP_002420130.1 218529314 7115581 1349427..1350140 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_1159 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 1350140 7115581 Mchl_1318 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002420130.1 1349427 D 440085 CDS YP_002420131.1 218529315 7115582 1350355..1350564 1 NC_011757.1 KEGG: mrd:Mrad2831_2336 hypothetical protein; hypothetical protein 1350564 7115582 Mchl_1319 Methylobacterium extorquens CM4 hypothetical protein YP_002420131.1 1350355 D 440085 CDS YP_002420132.1 218529316 7115583 complement(1350626..1350922) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_1160 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 1350922 7115583 Mchl_1320 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002420132.1 1350626 R 440085 CDS YP_002420133.1 218529317 7115584 1351282..1353045 1 NC_011757.1 KEGG: mex:Mext_1161 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; type I secretion system ATPase 1353045 7115584 Mchl_1321 Methylobacterium extorquens CM4 type I secretion system ATPase YP_002420133.1 1351282 D 440085 CDS YP_002420134.1 218529318 7115585 1353055..1354431 1 NC_011757.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD; KEGG: mex:Mext_1162 HlyD family type I secretion membrane fusion protein; HlyD family type I secretion membrane fusion protein 1354431 7115585 Mchl_1322 Methylobacterium extorquens CM4 HlyD family type I secretion membrane fusion protein YP_002420134.1 1353055 D 440085 CDS YP_002420135.1 218529319 7115586 1354510..1358916 1 NC_011757.1 KEGG: mex:Mext_1163 hypothetical protein; hypothetical protein 1358916 7115586 Mchl_1323 Methylobacterium extorquens CM4 hypothetical protein YP_002420135.1 1354510 D 440085 CDS YP_002420136.1 218529320 7115587 complement(1359067..1361025) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_1164 cellulose synthase (UDP-forming); cellulose synthase 1361025 7115587 Mchl_1324 Methylobacterium extorquens CM4 cellulose synthase YP_002420136.1 1359067 R 440085 CDS YP_002420137.1 218529321 7115588 complement(1361022..1362197) 1 NC_011757.1 KEGG: mex:Mext_1165 hypothetical protein; hypothetical protein 1362197 7115588 Mchl_1325 Methylobacterium extorquens CM4 hypothetical protein YP_002420137.1 1361022 R 440085 CDS YP_002420138.1 218529322 7115589 complement(1362233..1363987) 1 NC_011757.1 KEGG: mex:Mext_1166 hypothetical protein; hypothetical protein 1363987 7115589 Mchl_1326 Methylobacterium extorquens CM4 hypothetical protein YP_002420138.1 1362233 R 440085 CDS YP_002420139.1 218529323 7115590 complement(1365143..1365943) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1167 ABC transporter; ABC transporter 1365943 7115590 Mchl_1327 Methylobacterium extorquens CM4 ABC transporter YP_002420139.1 1365143 R 440085 CDS YP_002420140.1 218529324 7115591 complement(1365937..1366935) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1168 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 1366935 7115591 Mchl_1328 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420140.1 1365937 R 440085 CDS YP_002420141.1 218529325 7115592 complement(1366945..1368030) 1 NC_011757.1 KEGG: mex:Mext_1169 ABC transporter substrate-binding protein; ABC transporter substrate-binding protein 1368030 7115592 Mchl_1329 Methylobacterium extorquens CM4 ABC transporter substrate-binding protein YP_002420141.1 1366945 R 440085 CDS YP_002420142.1 218529326 7113652 1368570..1369715 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_1170 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 1369715 7113652 Mchl_1330 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002420142.1 1368570 D 440085 CDS YP_002420143.1 218529327 7116304 1369734..1370831 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_1171 alkanesulfonate monooxygenase; alkanesulfonate monooxygenase 1370831 7116304 Mchl_1331 Methylobacterium extorquens CM4 alkanesulfonate monooxygenase YP_002420143.1 1369734 D 440085 CDS YP_002420144.1 218529328 7116305 1370831..1371772 1 NC_011757.1 TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; SMART: extracellular solute-binding protein family 3; KEGG: mex:Mext_1172 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 1371772 7116305 Mchl_1332 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002420144.1 1370831 D 440085 CDS YP_002420145.1 218529329 7116306 1371799..1372341 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_1173 cupin 2 domain-containing protein; cupin 1372341 7116306 Mchl_1333 Methylobacterium extorquens CM4 cupin YP_002420145.1 1371799 D 440085 CDS YP_002420146.1 218529330 7116308 1373072..1373275 1 NC_011757.1 KEGG: mex:Mext_1175 hypothetical protein; hypothetical protein 1373275 7116308 Mchl_1335 Methylobacterium extorquens CM4 hypothetical protein YP_002420146.1 1373072 D 440085 CDS YP_002420147.1 218529331 7116309 1373361..1374206 1 NC_011757.1 KEGG: mex:Mext_1176 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; serine O-acetyltransferase 1374206 7116309 Mchl_1336 Methylobacterium extorquens CM4 serine O-acetyltransferase YP_002420147.1 1373361 D 440085 CDS YP_002420148.1 218529332 7116310 1374627..1376018 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_1177 cyclic nucleotide-binding; cyclic nucleotide-binding protein 1376018 7116310 Mchl_1337 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002420148.1 1374627 D 440085 CDS YP_002420149.1 218529333 7116311 1376005..1378029 1 NC_011757.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mex:Mext_1178 SufS subfamily cysteine desulfurase; SufS subfamily cysteine desulfurase 1378029 7116311 Mchl_1338 Methylobacterium extorquens CM4 SufS subfamily cysteine desulfurase YP_002420149.1 1376005 D 440085 CDS YP_002420150.1 218529334 7116312 1378567..1379544 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_1181 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1379544 7116312 Mchl_1339 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002420150.1 1378567 D 440085 CDS YP_002420151.1 218529335 7116313 1379763..1380632 1 NC_011757.1 KEGG: mex:Mext_1182 porin; porin 1380632 7116313 Mchl_1340 Methylobacterium extorquens CM4 porin YP_002420151.1 1379763 D 440085 CDS YP_002420152.1 218529336 7116314 1381022..1381273 1 NC_011757.1 KEGG: mex:Mext_1183 hypothetical protein; hypothetical protein 1381273 7116314 Mchl_1341 Methylobacterium extorquens CM4 hypothetical protein YP_002420152.1 1381022 D 440085 CDS YP_002420153.1 218529337 7116315 1381285..1381698 1 NC_011757.1 PFAM: protein of unknown function DUF1236; KEGG: mex:Mext_1184 hypothetical protein; hypothetical protein 1381698 7116315 Mchl_1342 Methylobacterium extorquens CM4 hypothetical protein YP_002420153.1 1381285 D 440085 CDS YP_002420154.1 218529338 7116316 complement(1381968..1382189) 1 NC_011757.1 hypothetical protein 1382189 7116316 Mchl_1343 Methylobacterium extorquens CM4 hypothetical protein YP_002420154.1 1381968 R 440085 CDS YP_002420155.1 218529339 7116318 1383040..1383249 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_1185 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 1383249 7116318 Mchl_1345 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002420155.1 1383040 D 440085 CDS YP_002420156.1 218529340 7116319 1383457..1383702 1 NC_011757.1 KEGG: mex:Mext_1186 signal peptide; signal peptide 1383702 7116319 Mchl_1346 Methylobacterium extorquens CM4 signal peptide YP_002420156.1 1383457 D 440085 CDS YP_002420157.1 218529341 7116320 complement(1383926..1384294) 1 NC_011757.1 KEGG: mex:Mext_1187 hypothetical protein; hypothetical protein 1384294 7116320 Mchl_1347 Methylobacterium extorquens CM4 hypothetical protein YP_002420157.1 1383926 R 440085 CDS YP_002420158.1 218529342 7116321 1384613..1386571 1 NC_011757.1 KEGG: mex:Mext_1188 hypothetical protein; hypothetical protein 1386571 7116321 Mchl_1348 Methylobacterium extorquens CM4 hypothetical protein YP_002420158.1 1384613 D 440085 CDS YP_002420159.1 218529343 7116322 complement(1386743..1387474) 1 NC_011757.1 KEGG: mex:Mext_1189 ABC-type Co2+ transport system, periplasmic component; cobalt ABC transporter periplasmic protein 1387474 7116322 Mchl_1349 Methylobacterium extorquens CM4 cobalt ABC transporter periplasmic protein YP_002420159.1 1386743 R 440085 CDS YP_002420160.1 218529344 7116323 complement(1387885..1390935) 1 NC_011757.1 KEGG: mex:Mext_1190 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 1390935 7116323 Mchl_1350 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002420160.1 1387885 R 440085 CDS YP_002420161.1 218529345 7116324 complement(1391117..1391725) 1 NC_011757.1 PFAM: membrane protein of uknown function UCP014873; KEGG: mex:Mext_1191 hypothetical protein; membrane protein 1391725 7116324 Mchl_1351 Methylobacterium extorquens CM4 membrane protein YP_002420161.1 1391117 R 440085 CDS YP_002420162.1 218529346 7116325 1392229..1394196 1 NC_011757.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 1394196 7116325 Mchl_1352 Methylobacterium extorquens CM4 myosin-cross-reactive antigen YP_002420162.1 1392229 D 440085 CDS YP_002420163.1 218529347 7116326 1394495..1395538 1 NC_011757.1 KEGG: mex:Mext_1193 hypothetical protein; hypothetical protein 1395538 7116326 Mchl_1353 Methylobacterium extorquens CM4 hypothetical protein YP_002420163.1 1394495 D 440085 CDS YP_002420164.1 218529348 7116327 1395822..1396286 1 NC_011757.1 involved in the assembly of the urease metallocenter; nickel donor; urease accessory protein UreE 1396286 ureE 7116327 ureE Methylobacterium extorquens CM4 urease accessory protein UreE YP_002420164.1 1395822 D 440085 CDS YP_002420165.1 218529349 7116328 1396291..1396971 1 NC_011757.1 PFAM: urease accessory protein UreF; KEGG: mex:Mext_1195 urease accessory protein UreF; urease accessory protein UreF 1396971 7116328 Mchl_1355 Methylobacterium extorquens CM4 urease accessory protein UreF YP_002420165.1 1396291 D 440085 CDS YP_002420166.1 218529350 7116329 1396985..1397680 1 NC_011757.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; bifunctional urease subunit gamma/beta 1397680 7116329 Mchl_1356 Methylobacterium extorquens CM4 bifunctional urease subunit gamma/beta YP_002420166.1 1396985 D 440085 CDS YP_002420167.1 218529351 7116330 1397696..1399408 1 NC_011757.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1399408 ureC 7116330 ureC Methylobacterium extorquens CM4 urease subunit alpha YP_002420167.1 1397696 D 440085 CDS YP_002420168.1 218529352 7116331 1399405..1400049 1 NC_011757.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: mex:Mext_1198 urease accessory protein UreG; urease accessory protein UreG 1400049 7116331 Mchl_1358 Methylobacterium extorquens CM4 urease accessory protein UreG YP_002420168.1 1399405 D 440085 CDS YP_002420169.1 218529353 7116332 1400049..1400933 1 NC_011757.1 PFAM: urease accessory protein UreD; KEGG: mex:Mext_1199 urease accessory protein UreD; urease accessory protein UreD 1400933 7116332 Mchl_1359 Methylobacterium extorquens CM4 urease accessory protein UreD YP_002420169.1 1400049 D 440085 CDS YP_002420170.1 218529354 7116333 1401123..1402364 1 NC_011757.1 TIGRFAM: urea ABC transporter urea binding protein; KEGG: mex:Mext_1200 UreA ABC transporter UreA binding protein; urea ABC transporter urea binding protein 1402364 7116333 Mchl_1360 Methylobacterium extorquens CM4 urea ABC transporter urea binding protein YP_002420170.1 1401123 D 440085 CDS YP_002420171.1 218529355 7116335 complement(1403576..1405774) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_1202 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 1405774 7116335 Mchl_1362 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002420171.1 1403576 R 440085 CDS YP_002420172.1 218529356 7116336 1406524..1407714 1 NC_011757.1 KEGG: mex:Mext_1203 hypothetical protein; hypothetical protein 1407714 7116336 Mchl_1363 Methylobacterium extorquens CM4 hypothetical protein YP_002420172.1 1406524 D 440085 CDS YP_002420173.1 218529357 7116337 complement(1407838..1408206) 1 NC_011757.1 KEGG: mex:Mext_1204 hypothetical protein; hypothetical protein 1408206 7116337 Mchl_1364 Methylobacterium extorquens CM4 hypothetical protein YP_002420173.1 1407838 R 440085 CDS YP_002420174.1 218529358 7116338 complement(1408239..1408682) 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_1205 OsmC family protein; OsmC family protein 1408682 7116338 Mchl_1365 Methylobacterium extorquens CM4 OsmC family protein YP_002420174.1 1408239 R 440085 CDS YP_002420175.1 218529359 7116339 1408949..1409398 1 NC_011757.1 KEGG: mex:Mext_1206 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor protein 1409398 7116339 Mchl_1366 Methylobacterium extorquens CM4 PAS/PAC sensor protein YP_002420175.1 1408949 D 440085 CDS YP_002420176.1 218529360 7116340 1409499..1410749 1 NC_011757.1 catalyzes the formation of oxalyl-CoA from oxalate and formyl-CoA; formyl-coenzyme A transferase 1410749 7116340 Mchl_1367 Methylobacterium extorquens CM4 formyl-coenzyme A transferase YP_002420176.1 1409499 D 440085 CDS YP_002420177.1 218529361 7116341 complement(1410989..1411708) 1 NC_011757.1 PFAM: phospholipase/carboxylesterase; KEGG: mex:Mext_1208 phospholipase/carboxylesterase; phospholipase/carboxylesterase 1411708 7116341 Mchl_1368 Methylobacterium extorquens CM4 phospholipase/carboxylesterase YP_002420177.1 1410989 R 440085 CDS YP_002420178.1 218529362 7116342 complement(1411974..1413725) 1 NC_011757.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 1413725 7116342 Mchl_1369 Methylobacterium extorquens CM4 oxalyl-CoA decarboxylase YP_002420178.1 1411974 R 440085 CDS YP_002420179.1 218529363 7116343 complement(1414201..1416546) 1 NC_011757.1 PFAM: Domain of unknown function DUF1929; KEGG: mex:Mext_1210 galactose oxidase; Galactose oxidase 1416546 7116343 Mchl_1370 Methylobacterium extorquens CM4 Galactose oxidase YP_002420179.1 1414201 R 440085 CDS YP_002420180.1 218529364 7116344 complement(1416844..1418169) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1211 major facilitator transporter; major facilitator superfamily protein 1418169 7116344 Mchl_1371 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002420180.1 1416844 R 440085 CDS YP_002420181.1 218529365 7116345 complement(1418434..1419744) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1212 major facilitator transporter; major facilitator superfamily protein 1419744 7116345 Mchl_1372 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002420181.1 1418434 R 440085 CDS YP_002420182.1 218529366 7116346 1420285..1420725 1 NC_011757.1 PFAM: CBS domain containing protein; KEGG: mex:Mext_1213 CBS domain-containing protein; signal transduction protein with CBS domains 1420725 7116346 Mchl_1373 Methylobacterium extorquens CM4 signal transduction protein with CBS domains YP_002420182.1 1420285 D 440085 CDS YP_002420183.1 218529367 7116347 1420880..1421173 1 NC_011757.1 KEGG: mex:Mext_1214 hypothetical protein; hypothetical protein 1421173 7116347 Mchl_1374 Methylobacterium extorquens CM4 hypothetical protein YP_002420183.1 1420880 D 440085 CDS YP_002420184.1 218529368 7116348 1421196..1423052 1 NC_011757.1 KEGG: mex:Mext_1215 hypothetical protein; hypothetical protein 1423052 7116348 Mchl_1375 Methylobacterium extorquens CM4 hypothetical protein YP_002420184.1 1421196 D 440085 CDS YP_002420185.1 218529369 7116349 1423272..1423439 1 NC_011757.1 KEGG: mex:Mext_1216 hypothetical protein; hypothetical protein 1423439 7116349 Mchl_1376 Methylobacterium extorquens CM4 hypothetical protein YP_002420185.1 1423272 D 440085 CDS YP_002420186.1 218529370 7116350 complement(1423421..1423645) 1 NC_011757.1 KEGG: mpo:Mpop_1156 hypothetical protein; hypothetical protein 1423645 7116350 Mchl_1377 Methylobacterium extorquens CM4 hypothetical protein YP_002420186.1 1423421 R 440085 CDS YP_002420187.1 218529371 7116351 complement(1423787..1425076) 1 NC_011757.1 TIGRFAM: formyl-CoA transferase; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: mex:Mext_1217 formyl-CoA transferase; formyl-CoA transferase 1425076 7116351 Mchl_1378 Methylobacterium extorquens CM4 formyl-CoA transferase YP_002420187.1 1423787 R 440085 CDS YP_002420188.1 218529372 7116352 1425497..1426180 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_1218 GntR domain-containing protein; GntR family transcriptional regulator 1426180 7116352 Mchl_1379 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002420188.1 1425497 D 440085 CDS YP_002420189.1 218529373 7116353 complement(1426310..1427410) 1 NC_011757.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: mex:Mext_1219 cobalamin synthesis protein P47K; cobalamin synthesis protein P47K 1427410 7116353 Mchl_1380 Methylobacterium extorquens CM4 cobalamin synthesis protein P47K YP_002420189.1 1426310 R 440085 CDS YP_002420190.1 218529374 7116354 complement(1427542..1429032) 1 NC_011757.1 PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: mex:Mext_1220 serine-type D-Ala-D-Ala carboxypeptidase; serine-type D-Ala-D-Ala carboxypeptidase 1429032 7116354 Mchl_1381 Methylobacterium extorquens CM4 serine-type D-Ala-D-Ala carboxypeptidase YP_002420190.1 1427542 R 440085 CDS YP_002420191.1 218529375 7116355 1429304..1429942 1 NC_011757.1 KEGG: mex:Mext_1221 hypothetical protein; hypothetical protein 1429942 7116355 Mchl_1382 Methylobacterium extorquens CM4 hypothetical protein YP_002420191.1 1429304 D 440085 CDS YP_002420192.1 218529376 7116356 1430106..1430543 1 NC_011757.1 KEGG: mex:Mext_1222 hypothetical protein; hypothetical protein 1430543 7116356 Mchl_1383 Methylobacterium extorquens CM4 hypothetical protein YP_002420192.1 1430106 D 440085 CDS YP_002420193.1 218529377 7116357 1430636..1430920 1 NC_011757.1 KEGG: mex:Mext_1223 hypothetical protein; hypothetical protein 1430920 7116357 Mchl_1384 Methylobacterium extorquens CM4 hypothetical protein YP_002420193.1 1430636 D 440085 CDS YP_002420194.1 218529378 7116358 complement(1431014..1432255) 1 NC_011757.1 PFAM: monooxygenase FAD-binding; KEGG: mex:Mext_1224 monooxygenase FAD-binding; FAD-binding monooxygenase 1432255 7116358 Mchl_1385 Methylobacterium extorquens CM4 FAD-binding monooxygenase YP_002420194.1 1431014 R 440085 CDS YP_002420195.1 218529379 7116359 1433088..1433444 1 NC_011757.1 TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mex:Mext_1225 queuosine biosynthesis protein QueD; queuosine biosynthesis protein QueD 1433444 7116359 Mchl_1386 Methylobacterium extorquens CM4 queuosine biosynthesis protein QueD YP_002420195.1 1433088 D 440085 CDS YP_002420196.1 218529380 7116360 1433447..1434178 1 NC_011757.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: mex:Mext_1226 ExsB protein; exsB protein 1434178 7116360 Mchl_1387 Methylobacterium extorquens CM4 exsB protein YP_002420196.1 1433447 D 440085 CDS YP_002420197.1 218529381 7116361 1434189..1434926 1 NC_011757.1 PFAM: LmbE family protein; KEGG: mex:Mext_1227 LmbE family protein; LmbE family protein 1434926 7116361 Mchl_1388 Methylobacterium extorquens CM4 LmbE family protein YP_002420197.1 1434189 D 440085 CDS YP_002420198.1 218529382 7116362 1435017..1435868 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_1228 glycosyl transferase; family 2 glycosyl transferase 1435868 7116362 Mchl_1389 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002420198.1 1435017 D 440085 CDS YP_002420199.1 218529383 7116363 1436262..1436444 1 NC_011757.1 KEGG: mex:Mext_1229 hypothetical protein; hypothetical protein 1436444 7116363 Mchl_1390 Methylobacterium extorquens CM4 hypothetical protein YP_002420199.1 1436262 D 440085 CDS YP_002420200.1 218529384 7116364 1436445..1436672 1 NC_011757.1 KEGG: mpo:Mpop_1168 hypothetical protein; hypothetical protein 1436672 7116364 Mchl_1391 Methylobacterium extorquens CM4 hypothetical protein YP_002420200.1 1436445 D 440085 CDS YP_002420201.1 218529385 7116365 1436735..1437028 1 NC_011757.1 KEGG: mex:Mext_1230 hypothetical protein; hypothetical protein 1437028 7116365 Mchl_1392 Methylobacterium extorquens CM4 hypothetical protein YP_002420201.1 1436735 D 440085 CDS YP_002420202.1 218529386 7116366 complement(1437176..1438225) 1 NC_011757.1 KEGG: mex:Mext_1231 hypothetical protein; hypothetical protein 1438225 7116366 Mchl_1393 Methylobacterium extorquens CM4 hypothetical protein YP_002420202.1 1437176 R 440085 CDS YP_002420203.1 218529387 7116367 complement(1438286..1439374) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_1232 glycosyl transferase; family 2 glycosyl transferase 1439374 7116367 Mchl_1394 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002420203.1 1438286 R 440085 CDS YP_002420204.1 218529388 7116368 complement(1439379..1440479) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1233 glycosyl transferase group 1; group 1 glycosyl transferase 1440479 7116368 Mchl_1395 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002420204.1 1439379 R 440085 CDS YP_002420205.1 218529389 7116369 complement(1440988..1441311) 1 NC_011757.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: mex:Mext_1234 HPr family phosphocarrier protein; phosphocarrier, HPr family 1441311 7116369 Mchl_1396 Methylobacterium extorquens CM4 phosphocarrier, HPr family YP_002420205.1 1440988 R 440085 CDS YP_002420206.1 218529390 7116370 complement(1441443..1441844) 1 NC_011757.1 PFAM: PTS system fructose subfamily IIA component; KEGG: mex:Mext_1235 PTS system fructose subfamily IIA component; PTS system fructose subfamily IIA component 1441844 7116370 Mchl_1397 Methylobacterium extorquens CM4 PTS system fructose subfamily IIA component YP_002420206.1 1441443 R 440085 CDS YP_002420207.1 218529391 7116371 complement(1441970..1442509) 1 NC_011757.1 KEGG: mex:Mext_1236 HPr kinase; HPr kinase 1442509 7116371 Mchl_1398 Methylobacterium extorquens CM4 HPr kinase YP_002420207.1 1441970 R 440085 CDS YP_002420208.1 218529392 7116372 complement(1442506..1444356) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_1237 ATPase domain-containing protein; histidine kinase 1444356 7116372 Mchl_1399 Methylobacterium extorquens CM4 histidine kinase YP_002420208.1 1442506 R 440085 CDS YP_002420209.1 218529393 7116373 complement(1444385..1445098) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mpo:Mpop_1179 transcriptional regulator; transcriptional regulator 1445098 7116373 Mchl_1400 Methylobacterium extorquens CM4 transcriptional regulator YP_002420209.1 1444385 R 440085 CDS YP_002420210.1 218529394 7116374 1445497..1446312 1 NC_011757.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mex:Mext_1239 pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 1446312 7116374 Mchl_1401 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002420210.1 1445497 D 440085 CDS YP_002420211.1 218529395 7116375 1446473..1448278 1 NC_011757.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1448278 7116375 Mchl_1402 Methylobacterium extorquens CM4 GTP-binding protein LepA YP_002420211.1 1446473 D 440085 CDS YP_002420212.1 218529396 7116376 1448718..1449971 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: mex:Mext_1241 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 1449971 7116376 Mchl_1403 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002420212.1 1448718 D 440085 CDS YP_002420213.1 218529397 7116377 1450063..1453233 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_1242 CzcA family heavy metal efflux protein; CzcA family heavy metal efflux pump 1453233 7116377 Mchl_1404 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002420213.1 1450063 D 440085 CDS YP_002420214.1 218529398 7116379 complement(1453688..1454761) 1 NC_011757.1 KEGG: mex:Mext_1244 hypothetical protein; hypothetical protein 1454761 7116379 Mchl_1406 Methylobacterium extorquens CM4 hypothetical protein YP_002420214.1 1453688 R 440085 CDS YP_002420215.1 218529399 7116380 complement(1454809..1457862) 1 NC_011757.1 PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: mex:Mext_1245 glycosyl transferase family protein; glycosyl transferase family protein 1457862 7116380 Mchl_1407 Methylobacterium extorquens CM4 glycosyl transferase family protein YP_002420215.1 1454809 R 440085 CDS YP_002420216.1 218529400 7116381 complement(1458080..1459279) 1 NC_011757.1 KEGG: mex:Mext_1247 hypothetical protein; hypothetical protein 1459279 7116381 Mchl_1408 Methylobacterium extorquens CM4 hypothetical protein YP_002420216.1 1458080 R 440085 CDS YP_002420217.1 218529401 7116382 1459483..1459899 1 NC_011757.1 PFAM: flagellar FlbT family protein; KEGG: mex:Mext_1248 flagellar FlbT family protein; flagellar FlbT family protein 1459899 7116382 Mchl_1409 Methylobacterium extorquens CM4 flagellar FlbT family protein YP_002420217.1 1459483 D 440085 CDS YP_002420218.1 218529402 7116383 complement(1459998..1460213) 1 NC_011757.1 KEGG: mex:Mext_1249 hypothetical protein; hypothetical protein 1460213 7116383 Mchl_1410 Methylobacterium extorquens CM4 hypothetical protein YP_002420218.1 1459998 R 440085 CDS YP_002420219.1 218529403 7116384 complement(1460308..1461471) 1 NC_011757.1 PFAM: acyltransferase 3; KEGG: mex:Mext_1250 acyltransferase 3; acyltransferase 3 1461471 7116384 Mchl_1411 Methylobacterium extorquens CM4 acyltransferase 3 YP_002420219.1 1460308 R 440085 CDS YP_002420220.1 218529404 7116548 1461775..1463160 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_1251 metal-dependent phosphohydrolase; metal dependent phosphohydrolase 1463160 7116548 Mchl_1412 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002420220.1 1461775 D 440085 CDS YP_002420221.1 218529405 7116631 complement(1463274..1463651) 1 NC_011757.1 KEGG: mex:Mext_1252 hypothetical protein; hypothetical protein 1463651 7116631 Mchl_1413 Methylobacterium extorquens CM4 hypothetical protein YP_002420221.1 1463274 R 440085 CDS YP_002420222.1 218529406 7116632 1463828..1464256 1 NC_011757.1 PFAM: protein of unknown function DUF442; KEGG: mex:Mext_1253 hypothetical protein; hypothetical protein 1464256 7116632 Mchl_1414 Methylobacterium extorquens CM4 hypothetical protein YP_002420222.1 1463828 D 440085 CDS YP_002420223.1 218529407 7116633 complement(1464375..1465127) 1 NC_011757.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 1465127 7116633 Mchl_1415 Methylobacterium extorquens CM4 methionine aminopeptidase YP_002420223.1 1464375 R 440085 CDS YP_002420224.1 218529408 7116634 1465736..1466395 1 NC_011757.1 KEGG: mex:Mext_1255 hypothetical protein; hypothetical protein 1466395 7116634 Mchl_1416 Methylobacterium extorquens CM4 hypothetical protein YP_002420224.1 1465736 D 440085 CDS YP_002420225.1 218529409 7116635 complement(1466430..1467347) 1 NC_011757.1 KEGG: mex:Mext_1256 hypothetical protein; hypothetical protein 1467347 7116635 Mchl_1417 Methylobacterium extorquens CM4 hypothetical protein YP_002420225.1 1466430 R 440085 CDS YP_002420226.1 218529410 7116636 complement(1467722..1468579) 1 NC_011757.1 PFAM: protein of unknown function DUF849; KEGG: mex:Mext_1257 hypothetical protein; hypothetical protein 1468579 7116636 Mchl_1418 Methylobacterium extorquens CM4 hypothetical protein YP_002420226.1 1467722 R 440085 CDS YP_002420227.1 218529411 7116637 complement(1468579..1469934) 1 NC_011757.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_1258 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 1469934 7116637 Mchl_1419 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002420227.1 1468579 R 440085 CDS YP_002420228.1 218529412 7116638 complement(1469924..1471789) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_1259 ATPase domain-containing protein; histidine kinase 1471789 7116638 Mchl_1420 Methylobacterium extorquens CM4 histidine kinase YP_002420228.1 1469924 R 440085 CDS YP_002420229.1 218529413 7116639 complement(1472053..1472934) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1260 ABC transporter; ABC transporter 1472934 7116639 Mchl_1421 Methylobacterium extorquens CM4 ABC transporter YP_002420229.1 1472053 R 440085 CDS YP_002420230.1 218529414 7116640 complement(1472943..1473764) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1261 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 1473764 7116640 Mchl_1422 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420230.1 1472943 R 440085 CDS YP_002420231.1 218529415 7116641 complement(1473777..1474757) 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_1262 NMT1/THI5-like domain-containing protein; family 3 extracellular solute-binding protein 1474757 7116641 Mchl_1423 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002420231.1 1473777 R 440085 CDS YP_002420232.1 218529416 7116642 complement(1475020..1475748) 1 NC_011757.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1475748 minC 7116642 minC Methylobacterium extorquens CM4 septum formation inhibitor YP_002420232.1 1475020 R 440085 CDS YP_002420233.1 218529417 7116643 complement(1475875..1477164) 1 NC_011757.1 KEGG: mex:Mext_1264 hypothetical protein; hypothetical protein 1477164 7116643 Mchl_1425 Methylobacterium extorquens CM4 hypothetical protein YP_002420233.1 1475875 R 440085 CDS YP_002420234.1 218529418 7116644 1477482..1479308 1 NC_011757.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: mex:Mext_1265 GTP-binding protein TypA; GTP-binding protein TypA 1479308 7116644 Mchl_1426 Methylobacterium extorquens CM4 GTP-binding protein TypA YP_002420234.1 1477482 D 440085 CDS YP_002420235.1 218529419 7116645 complement(1479451..1481139) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; CHASE3 domain protein; KEGG: mex:Mext_1266 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1481139 7116645 Mchl_1427 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002420235.1 1479451 R 440085 CDS YP_002420236.1 218529420 7116646 1481559..1482197 1 NC_011757.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1482197 minC 7116646 minC Methylobacterium extorquens CM4 septum formation inhibitor YP_002420236.1 1481559 D 440085 CDS YP_002420237.1 218529421 7116647 1482210..1483025 1 NC_011757.1 TIGRFAM: septum site-determining protein MinD; PFAM: cobyrinic acid ac-diamide synthase; KEGG: mex:Mext_1268 septum site-determining protein MinD; septum site-determining protein MinD 1483025 7116647 Mchl_1429 Methylobacterium extorquens CM4 septum site-determining protein MinD YP_002420237.1 1482210 D 440085 CDS YP_002420238.1 218529422 7116648 1483022..1483309 1 NC_011757.1 TIGRFAM: cell division topological specificity factor MinE; PFAM: septum formation topological specificity factor MinE; KEGG: mex:Mext_1269 cell division topological specificity factor MinE; cell division topological specificity factor MinE 1483309 7116648 Mchl_1430 Methylobacterium extorquens CM4 cell division topological specificity factor MinE YP_002420238.1 1483022 D 440085 CDS YP_002420239.1 218529423 7116650 complement(1483594..1484973) 1 NC_011757.1 PFAM: cytochrome P450; KEGG: mex:Mext_1270 cytochrome P450; cytochrome P450 1484973 7116650 Mchl_1432 Methylobacterium extorquens CM4 cytochrome P450 YP_002420239.1 1483594 R 440085 CDS YP_002420240.1 218529424 7116651 1485230..1486123 1 NC_011757.1 PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: mex:Mext_1271 SMP-30/gluconolaconase/LRE domain-containing protein; SMP-30/gluconolaconase/LRE domain-containing protein 1486123 7116651 Mchl_1433 Methylobacterium extorquens CM4 SMP-30/gluconolaconase/LRE domain-containing protein YP_002420240.1 1485230 D 440085 CDS YP_002420241.1 218529425 7116652 1486282..1488132 1 NC_011757.1 PFAM: glycoside hydrolase 15-related; KEGG: mpo:Mpop_1274 glycoside hydrolase 15-related; glycoside hydrolase 15-like protein 1488132 7116652 Mchl_1434 Methylobacterium extorquens CM4 glycoside hydrolase 15-like protein YP_002420241.1 1486282 D 440085 CDS YP_002420242.1 218529426 7116653 1488141..1489103 1 NC_011757.1 KEGG: mex:Mext_1273 dehydrogenase protein; dehydrogenase protein 1489103 7116653 Mchl_1435 Methylobacterium extorquens CM4 dehydrogenase protein YP_002420242.1 1488141 D 440085 CDS YP_002420243.1 218529427 7116654 1490128..1491573 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_1274 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 1491573 7116654 Mchl_1436 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002420243.1 1490128 D 440085 CDS YP_002420244.1 218529428 7116657 1492672..1494294 1 NC_011757.1 PFAM: extracellular solute-binding protein family 5; KEGG: mex:Mext_1277 extracellular solute-binding protein; family 5 extracellular solute-binding protein 1494294 7116657 Mchl_1439 Methylobacterium extorquens CM4 family 5 extracellular solute-binding protein YP_002420244.1 1492672 D 440085 CDS YP_002420245.1 218529429 7116658 1494453..1495406 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1278 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 1495406 7116658 Mchl_1440 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420245.1 1494453 D 440085 CDS YP_002420246.1 218529430 7116659 1495423..1496358 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1279 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 1496358 7116659 Mchl_1441 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420246.1 1495423 D 440085 CDS YP_002420247.1 218529431 7116660 1496355..1497410 1 NC_011757.1 KEGG: mex:Mext_1280 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase 1497410 7116660 Mchl_1442 Methylobacterium extorquens CM4 oligopeptide/dipeptide ABC transporter ATPase YP_002420247.1 1496355 D 440085 CDS YP_002420248.1 218529432 7116661 1497407..1498441 1 NC_011757.1 KEGG: mex:Mext_1281 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase 1498441 7116661 Mchl_1443 Methylobacterium extorquens CM4 oligopeptide/dipeptide ABC transporter ATPase YP_002420248.1 1497407 D 440085 CDS YP_002420249.1 218529433 7116662 complement(1498802..1500301) 1 NC_011757.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mex:Mext_1282 methylmalonate-semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase 1500301 7116662 Mchl_1444 Methylobacterium extorquens CM4 methylmalonate-semialdehyde dehydrogenase YP_002420249.1 1498802 R 440085 CDS YP_002420250.1 218529434 7116663 complement(1500367..1500843) 1 NC_011757.1 PFAM: cyclase/dehydrase; carbon monoxide dehydrogenase subunit G; KEGG: mex:Mext_1283 carbon monoxide dehydrogenase subunit G; carbon monoxide dehydrogenase subunit G 1500843 7116663 Mchl_1445 Methylobacterium extorquens CM4 carbon monoxide dehydrogenase subunit G YP_002420250.1 1500367 R 440085 CDS YP_002420251.1 218529435 7116664 complement(1500873..1501577) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1284 ABC transporter; ABC transporter 1501577 7116664 Mchl_1446 Methylobacterium extorquens CM4 ABC transporter YP_002420251.1 1500873 R 440085 CDS YP_002420252.1 218529436 7116665 complement(1501570..1502340) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1285 ABC transporter; ABC transporter 1502340 7116665 Mchl_1447 Methylobacterium extorquens CM4 ABC transporter YP_002420252.1 1501570 R 440085 CDS YP_002420253.1 218529437 7116666 complement(1502337..1503350) 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1286 inner-membrane translocator; inner-membrane translocator 1503350 7116666 Mchl_1448 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420253.1 1502337 R 440085 CDS YP_002420254.1 218529438 7116667 complement(1503362..1504252) 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1287 inner-membrane translocator; inner-membrane translocator 1504252 7116667 Mchl_1449 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420254.1 1503362 R 440085 CDS YP_002420255.1 218529439 7116668 complement(1504270..1505517) 1 NC_011757.1 PFAM: extracellular ligand-binding receptor; KEGG: mex:Mext_1288 extracellular ligand-binding receptor; extracellular ligand-binding receptor 1505517 7116668 Mchl_1450 Methylobacterium extorquens CM4 extracellular ligand-binding receptor YP_002420255.1 1504270 R 440085 CDS YP_002420256.1 218529440 7116669 complement(1505584..1507962) 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_1289 carbon-monoxide dehydrogenase (acceptor); carbon-monoxide dehydrogenase (acceptor) 1507962 7116669 Mchl_1451 Methylobacterium extorquens CM4 carbon-monoxide dehydrogenase (acceptor) YP_002420256.1 1505584 R 440085 CDS YP_002420257.1 218529441 7116670 complement(1507959..1508462) 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_1290 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 1508462 7116670 Mchl_1452 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002420257.1 1507959 R 440085 CDS YP_002420258.1 218529442 7116671 complement(1508459..1509337) 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: mex:Mext_1291 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 1509337 7116671 Mchl_1453 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002420258.1 1508459 R 440085 CDS YP_002420259.1 218529443 7116672 1509466..1510161 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1292 regulatory protein TetR; TetR family transcriptional regulator 1510161 7116672 Mchl_1454 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420259.1 1509466 D 440085 CDS YP_002420260.1 218529444 7116673 1510903..1512195 1 NC_011757.1 KEGG: mex:Mext_1293 amidase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; hydantoinase/carbamoylase family amidase 1512195 7116673 Mchl_1455 Methylobacterium extorquens CM4 hydantoinase/carbamoylase family amidase YP_002420260.1 1510903 D 440085 CDS YP_002420261.1 218529445 7116674 1512546..1513883 1 NC_011757.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase 1513883 7116674 Mchl_1456 Methylobacterium extorquens CM4 beta alanine--pyruvate transaminase YP_002420261.1 1512546 D 440085 CDS YP_002420262.1 218529446 7116677 complement(1515268..1515576) 1 NC_011757.1 KEGG: mex:Mext_1297 hypothetical protein; hypothetical protein 1515576 7116677 Mchl_1459 Methylobacterium extorquens CM4 hypothetical protein YP_002420262.1 1515268 R 440085 CDS YP_002420263.1 218529447 7116678 complement(1515850..1519185) 1 NC_011757.1 PFAM: helicase; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: mex:Mext_1298 DEAD/DEAH box helicase domain-containing protein; DEAD/DEAH box helicase 1519185 7116678 Mchl_1460 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002420263.1 1515850 R 440085 CDS YP_002420264.1 218529448 7116679 complement(1519464..1520702) 1 NC_011757.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: mex:Mext_1299 ammonium transporter; ammonium transporter 1520702 7116679 Mchl_1461 Methylobacterium extorquens CM4 ammonium transporter YP_002420264.1 1519464 R 440085 CDS YP_002420265.1 218529449 7116680 complement(1520796..1521809) 1 NC_011757.1 TIGRFAM: urea transporter; PFAM: Urea transporter; KEGG: mex:Mext_1300 UreA transporter; urea transporter 1521809 7116680 Mchl_1462 Methylobacterium extorquens CM4 urea transporter YP_002420265.1 1520796 R 440085 CDS YP_002420266.1 218529450 7116681 complement(1521825..1522760) 1 NC_011757.1 PFAM: urease accessory protein UreD; KEGG: mex:Mext_1301 urease accessory protein UreD; urease accessory protein UreD 1522760 7116681 Mchl_1463 Methylobacterium extorquens CM4 urease accessory protein UreD YP_002420266.1 1521825 R 440085 CDS YP_002420267.1 218529451 7116682 complement(1522765..1523412) 1 NC_011757.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: mex:Mext_1302 urease accessory protein UreG; urease accessory protein UreG 1523412 7116682 Mchl_1464 Methylobacterium extorquens CM4 urease accessory protein UreG YP_002420267.1 1522765 R 440085 CDS YP_002420268.1 218529452 7116683 complement(1523433..1524155) 1 NC_011757.1 PFAM: urease accessory protein UreF; KEGG: mex:Mext_1303 urease accessory protein UreF; urease accessory protein UreF 1524155 7116683 Mchl_1465 Methylobacterium extorquens CM4 urease accessory protein UreF YP_002420268.1 1523433 R 440085 CDS YP_002420269.1 218529453 7116684 complement(1524155..1524808) 1 NC_011757.1 PFAM: urease accessory protein UreE; KEGG: mex:Mext_1304 UreE urease accessory domain-containing protein; urease accessory protein UreE 1524808 7116684 Mchl_1466 Methylobacterium extorquens CM4 urease accessory protein UreE YP_002420269.1 1524155 R 440085 CDS YP_002420270.1 218529454 7116685 complement(1524832..1525215) 1 NC_011757.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1525215 ccrB 7116685 ccrB Methylobacterium extorquens CM4 camphor resistance protein CrcB YP_002420270.1 1524832 R 440085 CDS YP_002420271.1 218529455 7116686 complement(1525225..1525608) 1 NC_011757.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: mex:Mext_1306 CrcB protein; CrcB protein 1525608 7116686 Mchl_1468 Methylobacterium extorquens CM4 CrcB protein YP_002420271.1 1525225 R 440085 CDS YP_002420272.1 218529456 7116687 complement(1525670..1527388) 1 NC_011757.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1527388 ureC 7116687 ureC Methylobacterium extorquens CM4 urease subunit alpha YP_002420272.1 1525670 R 440085 CDS YP_002420273.1 218529457 7116688 complement(1527425..1527835) 1 NC_011757.1 KEGG: mex:Mext_1308 urease subunit beta; TIGRFAM: urease, subunit beta; PFAM: urease subunit beta; urease subunit beta 1527835 7116688 Mchl_1470 Methylobacterium extorquens CM4 urease subunit beta YP_002420273.1 1527425 R 440085 CDS YP_002420274.1 218529458 7116689 complement(1527860..1528162) 1 NC_011757.1 KEGG: mex:Mext_1309 urease subunit gamma; TIGRFAM: urease subunit gamma; PFAM: urease subunit gamma region; urease subunit gamma 1528162 7116689 Mchl_1471 Methylobacterium extorquens CM4 urease subunit gamma YP_002420274.1 1527860 R 440085 CDS YP_002420275.1 218529459 7116690 1528802..1530916 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_1310 TonB-dependent receptor plug; TonB-dependent receptor plug 1530916 7116690 Mchl_1472 Methylobacterium extorquens CM4 TonB-dependent receptor plug YP_002420275.1 1528802 D 440085 CDS YP_002420276.1 218529460 7116691 1530913..1531644 1 NC_011757.1 KEGG: mex:Mext_1311 ABC-type Co2+ transport system, periplasmic component; cobalt ABC transporter periplasmic protein 1531644 7116691 Mchl_1473 Methylobacterium extorquens CM4 cobalt ABC transporter periplasmic protein YP_002420276.1 1530913 D 440085 CDS YP_002420277.1 218529461 7116692 1532047..1532658 1 NC_011757.1 KEGG: mex:Mext_1312 hypothetical protein; hypothetical protein 1532658 7116692 Mchl_1474 Methylobacterium extorquens CM4 hypothetical protein YP_002420277.1 1532047 D 440085 CDS YP_002420278.1 218529462 7116694 1533213..1533554 1 NC_011757.1 KEGG: mex:Mext_1314 hypothetical protein; hypothetical protein 1533554 7116694 Mchl_1476 Methylobacterium extorquens CM4 hypothetical protein YP_002420278.1 1533213 D 440085 CDS YP_002420279.1 218529463 7116696 1534172..1534600 1 NC_011757.1 KEGG: mrd:Mrad2831_1299 hypothetical protein; hypothetical protein 1534600 7116696 Mchl_1477 Methylobacterium extorquens CM4 hypothetical protein YP_002420279.1 1534172 D 440085 CDS YP_002420280.1 218529464 7116697 complement(1534720..1535475) 1 NC_011757.1 PFAM: protein of unknown function DUF72; KEGG: mrd:Mrad2831_5900 hypothetical protein; hypothetical protein 1535475 7116697 Mchl_1478 Methylobacterium extorquens CM4 hypothetical protein YP_002420280.1 1534720 R 440085 CDS YP_002420281.1 218529465 7116698 complement(1536319..1537098) 1 NC_011757.1 KEGG: mrd:Mrad2831_4716 hypothetical protein; hypothetical protein 1537098 7116698 Mchl_1479 Methylobacterium extorquens CM4 hypothetical protein YP_002420281.1 1536319 R 440085 CDS YP_002420282.1 218529466 7116699 complement(1537285..1537962) 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: acr:Acry_1146 metal-dependent phosphohydrolase; metal dependent phosphohydrolase 1537962 7116699 Mchl_1480 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002420282.1 1537285 R 440085 CDS YP_002420283.1 218529467 7116700 1538081..1539046 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: bac:BamMC406_5748 transcriptional regulator, AraC family; AraC family transcriptional regulator 1539046 7116700 Mchl_1481 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420283.1 1538081 D 440085 CDS YP_002420284.1 218529468 7116701 complement(1539122..1539964) 1 NC_011757.1 KEGG: met:M446_0536 hypothetical protein; hypothetical protein 1539964 7116701 Mchl_1482 Methylobacterium extorquens CM4 hypothetical protein YP_002420284.1 1539122 R 440085 CDS YP_002420285.1 218529469 7116703 complement(1540615..1541013) 1 NC_011757.1 KEGG: mrd:Mrad2831_5275 hypothetical protein; hypothetical protein 1541013 7116703 Mchl_1484 Methylobacterium extorquens CM4 hypothetical protein YP_002420285.1 1540615 R 440085 CDS YP_002420286.1 218529470 7116704 complement(1541405..1541671) 1 NC_011757.1 KEGG: mex:Mext_1890 hypothetical protein; hypothetical protein 1541671 7116704 Mchl_1485 Methylobacterium extorquens CM4 hypothetical protein YP_002420286.1 1541405 R 440085 CDS YP_002420287.1 218529471 7116705 complement(1542105..1543526) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; KEGG: met:M446_5593 integral membrane sensor signal transduction histidine kinase; histidine kinase 1543526 7116705 Mchl_1486 Methylobacterium extorquens CM4 histidine kinase YP_002420287.1 1542105 R 440085 CDS YP_002420288.1 218529472 7116708 1545996..1546364 1 NC_011757.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: mex:Mext_0135 lipoprotein A; lipoprotein A 1546364 7116708 Mchl_1489 Methylobacterium extorquens CM4 lipoprotein A YP_002420288.1 1545996 D 440085 CDS YP_002420289.1 218529473 7116709 1546494..1547261 1 NC_011757.1 KEGG: mex:Mext_0134 hypothetical protein; hypothetical protein 1547261 7116709 Mchl_1490 Methylobacterium extorquens CM4 hypothetical protein YP_002420289.1 1546494 D 440085 CDS YP_002420290.1 218529474 7116710 1547365..1548060 1 NC_011757.1 hypothetical protein 1548060 7116710 Mchl_1491 Methylobacterium extorquens CM4 hypothetical protein YP_002420290.1 1547365 D 440085 CDS YP_002420291.1 218529475 7116711 1548057..1548338 1 NC_011757.1 KEGG: mpo:Mpop_4885 hypothetical protein; hypothetical protein 1548338 7116711 Mchl_1492 Methylobacterium extorquens CM4 hypothetical protein YP_002420291.1 1548057 D 440085 CDS YP_002420292.1 218529476 7115101 complement(1548446..1549558) 1 NC_011757.1 PFAM: regulatory protein LuxR; KEGG: met:M446_4636 LuxR family transcriptional regulator; LuxR family transcriptional regulator 1549558 7115101 Mchl_1493 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002420292.1 1548446 R 440085 CDS YP_002420293.1 218529477 7115104 complement(1549916..1550752) 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mex:Mext_3531 integrase catalytic region; integrase catalytic subunit 1550752 7115104 Mchl_1494 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002420293.1 1549916 R 440085 CDS YP_002420294.1 218529478 7115105 complement(1550776..1551057) 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: mex:Mext_3530 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1551057 7115105 Mchl_1495 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002420294.1 1550776 R 440085 CDS YP_002420295.1 218529479 7115106 complement(1551116..1551277) 1 NC_011757.1 hypothetical protein 1551277 7115106 Mchl_1496 Methylobacterium extorquens CM4 hypothetical protein YP_002420295.1 1551116 R 440085 CDS YP_002420296.1 218529480 7115107 complement(1551309..1551614) 1 NC_011757.1 KEGG: mpo:Mpop_1280 hypothetical protein; hypothetical protein 1551614 7115107 Mchl_1497 Methylobacterium extorquens CM4 hypothetical protein YP_002420296.1 1551309 R 440085 CDS YP_002420297.1 218529481 7115108 complement(1551625..1552302) 1 NC_011757.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mpo:Mpop_1281 Sel1 domain protein repeat-containing protein; Sel1 domain-containing protein repeat-containing protein 1552302 7115108 Mchl_1498 Methylobacterium extorquens CM4 Sel1 domain-containing protein repeat-containing protein YP_002420297.1 1551625 R 440085 CDS YP_002420298.1 218529482 7115109 complement(1552320..1553408) 1 NC_011757.1 KEGG: mpo:Mpop_1282 hypothetical protein; hypothetical protein 1553408 7115109 Mchl_1499 Methylobacterium extorquens CM4 hypothetical protein YP_002420298.1 1552320 R 440085 CDS YP_002420299.1 218529483 7115110 complement(1553557..1555989) 1 NC_011757.1 KEGG: mpo:Mpop_1283 large subunit of N,N-dimethylformamidase; large subunit of N,N-dimethylformamidase 1555989 7115110 Mchl_1500 Methylobacterium extorquens CM4 large subunit of N,N-dimethylformamidase YP_002420299.1 1553557 R 440085 CDS YP_002420300.1 218529484 7115111 complement(1556112..1556552) 1 NC_011757.1 KEGG: mpo:Mpop_1284 hypothetical protein; hypothetical protein 1556552 7115111 Mchl_1501 Methylobacterium extorquens CM4 hypothetical protein YP_002420300.1 1556112 R 440085 CDS YP_002420301.1 218529485 7115112 complement(1556922..1557620) 1 NC_011757.1 KEGG: mpo:Mpop_1285 UreA ABC transporter ATP-binding protein UrtE; TIGRFAM: urea ABC transporter ATP-binding protein UrtE; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein UrtE 1557620 7115112 Mchl_1502 Methylobacterium extorquens CM4 urea ABC transporter ATP-binding protein UrtE YP_002420301.1 1556922 R 440085 CDS YP_002420302.1 218529486 7115113 complement(1557623..1558363) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mpo:Mpop_1286 ABC transporter; ABC transporter 1558363 7115113 Mchl_1503 Methylobacterium extorquens CM4 ABC transporter YP_002420302.1 1557623 R 440085 CDS YP_002420303.1 218529487 7115114 complement(1558379..1559500) 1 NC_011757.1 TIGRFAM: urea ABC transporter permease UrtC; PFAM: inner-membrane translocator; KEGG: mpo:Mpop_1287 UreA ABC transporter permease UrtC; urea ABC transporter permease UrtC 1559500 7115114 Mchl_1504 Methylobacterium extorquens CM4 urea ABC transporter permease UrtC YP_002420303.1 1558379 R 440085 CDS YP_002420304.1 218529488 7115115 complement(1559550..1560434) 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mpo:Mpop_1288 inner-membrane translocator; inner-membrane translocator 1560434 7115115 Mchl_1505 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420304.1 1559550 R 440085 CDS YP_002420305.1 218529489 7115116 complement(1560502..1561812) 1 NC_011757.1 KEGG: mpo:Mpop_1289 substrate-binding component of ABC transporter; ABC transporter substrate-binding protein 1561812 7115116 Mchl_1506 Methylobacterium extorquens CM4 ABC transporter substrate-binding protein YP_002420305.1 1560502 R 440085 CDS YP_002420306.1 218529490 7115119 1562910..1563326 1 NC_011757.1 PFAM: protein of unknown function DUF1486; KEGG: mpo:Mpop_3619 protein of unknown function DUF1486; hypothetical protein 1563326 7115119 Mchl_1509 Methylobacterium extorquens CM4 hypothetical protein YP_002420306.1 1562910 D 440085 CDS YP_002420307.1 218529491 7115121 1564448..1565572 1 NC_011757.1 PFAM: glucose sorbosone dehydrogenase; KEGG: mex:Mext_1315 glucose sorbosone dehydrogenase; glucose sorbosone dehydrogenase 1565572 7115121 Mchl_1511 Methylobacterium extorquens CM4 glucose sorbosone dehydrogenase YP_002420307.1 1564448 D 440085 CDS YP_002420308.1 218529492 7115122 complement(1565606..1566541) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_1316 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 1566541 7115122 Mchl_1512 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002420308.1 1565606 R 440085 CDS YP_002420309.1 218529493 7115123 complement(1566934..1567140) 1 NC_011757.1 KEGG: mex:Mext_1317 hypothetical protein; hypothetical protein 1567140 7115123 Mchl_1513 Methylobacterium extorquens CM4 hypothetical protein YP_002420309.1 1566934 R 440085 CDS YP_002420310.1 218529494 7115124 1567621..1568286 1 NC_011757.1 KEGG: mex:Mext_1318 hypothetical protein; hypothetical protein 1568286 7115124 Mchl_1514 Methylobacterium extorquens CM4 hypothetical protein YP_002420310.1 1567621 D 440085 CDS YP_002420311.1 218529495 7115125 1568303..1569808 1 NC_011757.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: mex:Mext_1319 hypothetical protein; hypothetical protein 1569808 7115125 Mchl_1515 Methylobacterium extorquens CM4 hypothetical protein YP_002420311.1 1568303 D 440085 CDS YP_002420312.1 218529496 7115126 1569874..1570845 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1320 hypothetical protein; hypothetical protein 1570845 7115126 Mchl_1516 Methylobacterium extorquens CM4 hypothetical protein YP_002420312.1 1569874 D 440085 CDS YP_002420313.1 218529497 7115127 1571230..1571970 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_1321 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1571970 7115127 Mchl_1517 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002420313.1 1571230 D 440085 CDS YP_002420314.1 218529498 7115130 complement(1573090..1573728) 1 NC_011757.1 KEGG: mex:Mext_1322 phosphoglycerate mutase 1 family protein; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase; phosphoglycerate mutase 1 family 1573728 7115130 Mchl_1520 Methylobacterium extorquens CM4 phosphoglycerate mutase 1 family YP_002420314.1 1573090 R 440085 CDS YP_002420315.1 218529499 7115131 1574000..1574467 1 NC_011757.1 KEGG: mex:Mext_1323 hypothetical protein; hypothetical protein 1574467 7115131 Mchl_1521 Methylobacterium extorquens CM4 hypothetical protein YP_002420315.1 1574000 D 440085 CDS YP_002420316.1 218529500 7115132 complement(1574691..1574876) 1 NC_011757.1 KEGG: mex:Mext_1324 hypothetical protein; hypothetical protein 1574876 7115132 Mchl_1522 Methylobacterium extorquens CM4 hypothetical protein YP_002420316.1 1574691 R 440085 CDS YP_002420317.1 218529501 7115133 1575131..1575349 1 NC_011757.1 KEGG: mrd:Mrad2831_6030 hypothetical protein; hypothetical protein 1575349 7115133 Mchl_1523 Methylobacterium extorquens CM4 hypothetical protein YP_002420317.1 1575131 D 440085 CDS YP_002420318.1 218529502 7115134 1575365..1575544 1 NC_011757.1 hypothetical protein 1575544 7115134 Mchl_1524 Methylobacterium extorquens CM4 hypothetical protein YP_002420318.1 1575365 D 440085 CDS YP_002420319.1 218529503 7115135 1575896..1576438 1 NC_011757.1 KEGG: mex:Mext_1325 hypothetical protein; hypothetical protein 1576438 7115135 Mchl_1525 Methylobacterium extorquens CM4 hypothetical protein YP_002420319.1 1575896 D 440085 CDS YP_002420320.1 218529504 7115136 1576551..1577315 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1326 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1577315 7115136 Mchl_1526 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002420320.1 1576551 D 440085 CDS YP_002420321.1 218529505 7115137 1577401..1577580 1 NC_011757.1 KEGG: mrd:Mrad2831_4249 hypothetical protein; hypothetical protein 1577580 7115137 Mchl_1527 Methylobacterium extorquens CM4 hypothetical protein YP_002420321.1 1577401 D 440085 CDS YP_002420322.1 218529506 7115138 1577638..1577880 1 NC_011757.1 KEGG: mex:Mext_1327 hypothetical protein; hypothetical protein 1577880 7115138 Mchl_1528 Methylobacterium extorquens CM4 hypothetical protein YP_002420322.1 1577638 D 440085 CDS YP_002420323.1 218529507 7115139 complement(1577967..1578857) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: mex:Mext_1328 alpha/beta hydrolase domain-containing protein; alpha/beta hydrolase fold-3 domain-containing protein 1578857 7115139 Mchl_1529 Methylobacterium extorquens CM4 alpha/beta hydrolase fold-3 domain-containing protein YP_002420323.1 1577967 R 440085 CDS YP_002420324.1 218529508 7115140 complement(1579657..1583151) 1 NC_011757.1 KEGG: mex:Mext_1329 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; multi-sensor hybrid histidine kinase 1583151 7115140 Mchl_1530 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002420324.1 1579657 R 440085 CDS YP_002420325.1 218529509 7115141 1583676..1585091 1 NC_011757.1 PFAM: cytochrome P450; KEGG: mex:Mext_1330 cytochrome P450; cytochrome P450 1585091 7115141 Mchl_1531 Methylobacterium extorquens CM4 cytochrome P450 YP_002420325.1 1583676 D 440085 CDS YP_002420326.1 218529510 7115142 1585081..1587516 1 NC_011757.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; KEGG: mex:Mext_1331 diguanylate cyclase; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 1587516 7115142 Mchl_1532 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_002420326.1 1585081 D 440085 CDS YP_002420327.1 218529511 7115143 complement(1587688..1588518) 1 NC_011757.1 PFAM: protein of unknown function DUF1194; KEGG: mex:Mext_1332 hypothetical protein; hypothetical protein 1588518 7115143 Mchl_1533 Methylobacterium extorquens CM4 hypothetical protein YP_002420327.1 1587688 R 440085 CDS YP_002420328.1 218529512 7115144 complement(1588531..1589511) 1 NC_011757.1 PFAM: ApbE family lipoprotein; KEGG: mex:Mext_1333 ApbE family lipoprotein; ApbE family lipoprotein 1589511 7115144 Mchl_1534 Methylobacterium extorquens CM4 ApbE family lipoprotein YP_002420328.1 1588531 R 440085 CDS YP_002420329.1 218529513 7115145 complement(1589516..1591630) 1 NC_011757.1 PFAM: FMN-binding domain protein; KEGG: mex:Mext_1334 FMN-binding domain-containing protein; FMN-binding domain-containing protein 1591630 7115145 Mchl_1535 Methylobacterium extorquens CM4 FMN-binding domain-containing protein YP_002420329.1 1589516 R 440085 CDS YP_002420330.1 218529514 7115146 complement(1591627..1592715) 1 NC_011757.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: mpo:Mpop_4869 40-residue YVTN family beta-propeller repeat protein; 40-residue YVTN family beta-propeller repeat-containing protein 1592715 7115146 Mchl_1536 Methylobacterium extorquens CM4 40-residue YVTN family beta-propeller repeat-containing protein YP_002420330.1 1591627 R 440085 CDS YP_002420331.1 218529515 7115147 complement(1592688..1593914) 1 NC_011757.1 KEGG: mex:Mext_1336 hypothetical protein; hypothetical protein 1593914 7115147 Mchl_1537 Methylobacterium extorquens CM4 hypothetical protein YP_002420331.1 1592688 R 440085 CDS YP_002420332.1 218529516 7115148 1594076..1594498 1 NC_011757.1 KEGG: mex:Mext_1337 cytochrome C550; cytochrome C550 1594498 7115148 Mchl_1538 Methylobacterium extorquens CM4 cytochrome C550 YP_002420332.1 1594076 D 440085 CDS YP_002420333.1 218529517 7115149 1594513..1595382 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_1338 extracellular solute-binding protein; family 3 extracellular solute-binding protein 1595382 7115149 Mchl_1539 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002420333.1 1594513 D 440085 CDS YP_002420334.1 218529518 7115150 1595682..1597445 1 NC_011757.1 TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: pyrrolo-quinoline quinone; KEGG: mex:Mext_1339 methanol/ethanol family PQQ-dependent dehydrogenase; methanol/ethanol family PQQ-dependent dehydrogenase 1597445 7115150 Mchl_1540 Methylobacterium extorquens CM4 methanol/ethanol family PQQ-dependent dehydrogenase YP_002420334.1 1595682 D 440085 CDS YP_002420335.1 218529519 7115152 complement(1597767..1599263) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1340 major facilitator transporter; major facilitator superfamily protein 1599263 7115152 Mchl_1542 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002420335.1 1597767 R 440085 CDS YP_002420336.1 218529520 7115153 1599733..1599975 1 NC_011757.1 KEGG: mex:Mext_1341 hypothetical protein; hypothetical protein 1599975 7115153 Mchl_1543 Methylobacterium extorquens CM4 hypothetical protein YP_002420336.1 1599733 D 440085 CDS YP_002420337.1 218529521 7115154 complement(1600030..1600710) 1 NC_011757.1 KEGG: mex:Mext_1342 hypothetical protein; hypothetical protein 1600710 7115154 Mchl_1544 Methylobacterium extorquens CM4 hypothetical protein YP_002420337.1 1600030 R 440085 CDS YP_002420338.1 218529522 7115155 complement(1600772..1600948) 1 NC_011757.1 KEGG: mex:Mext_1344 hypothetical protein; hypothetical protein 1600948 7115155 Mchl_1545 Methylobacterium extorquens CM4 hypothetical protein YP_002420338.1 1600772 R 440085 CDS YP_002420339.1 218529523 7115156 complement(1600945..1601445) 1 NC_011757.1 KEGG: mex:Mext_1345 hypothetical protein; hypothetical protein 1601445 7115156 Mchl_1546 Methylobacterium extorquens CM4 hypothetical protein YP_002420339.1 1600945 R 440085 CDS YP_002420340.1 218529524 7115157 complement(1601510..1602277) 1 NC_011757.1 KEGG: mex:Mext_1346 hypothetical protein; hypothetical protein 1602277 7115157 Mchl_1547 Methylobacterium extorquens CM4 hypothetical protein YP_002420340.1 1601510 R 440085 CDS YP_002420341.1 218529525 7115158 1602340..1602666 1 NC_011757.1 KEGG: mex:Mext_1347 hypothetical protein; hypothetical protein 1602666 7115158 Mchl_1548 Methylobacterium extorquens CM4 hypothetical protein YP_002420341.1 1602340 D 440085 CDS YP_002420342.1 218529526 7115159 complement(1602685..1603194) 1 NC_011757.1 KEGG: mex:Mext_1348 hypothetical protein; hypothetical protein 1603194 7115159 Mchl_1549 Methylobacterium extorquens CM4 hypothetical protein YP_002420342.1 1602685 R 440085 CDS YP_002420343.1 218529527 7115160 complement(1603191..1605308) 1 NC_011757.1 PFAM: peptidase M48 Ste24p; KEGG: mex:Mext_1349 peptidase M48 Ste24p; peptidase M48 Ste24p 1605308 7115160 Mchl_1550 Methylobacterium extorquens CM4 peptidase M48 Ste24p YP_002420343.1 1603191 R 440085 CDS YP_002420344.1 218529528 7115161 complement(1606330..1606728) 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_1351 cupin 2 domain-containing protein; cupin 1606728 7115161 Mchl_1551 Methylobacterium extorquens CM4 cupin YP_002420344.1 1606330 R 440085 CDS YP_002420345.1 218529529 7115162 complement(1606762..1607508) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_1352 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 1607508 7115162 Mchl_1552 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002420345.1 1606762 R 440085 CDS YP_002420346.1 218529530 7115163 complement(1607628..1608542) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1353 carbonate dehydratase; LysR family transcriptional regulator 1608542 7115163 Mchl_1553 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420346.1 1607628 R 440085 CDS YP_002420347.1 218529531 7115164 complement(1608715..1609551) 1 NC_011757.1 PFAM: protein of unknown function DUF849; KEGG: mex:Mext_1354 hypothetical protein; hypothetical protein 1609551 7115164 Mchl_1554 Methylobacterium extorquens CM4 hypothetical protein YP_002420347.1 1608715 R 440085 CDS YP_002420348.1 218529532 7115165 1609720..1610532 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_1355 UspA domain-containing protein; UspA domain-containing protein 1610532 7115165 Mchl_1555 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002420348.1 1609720 D 440085 CDS YP_002420349.1 218529533 7115166 1610532..1610858 1 NC_011757.1 PFAM: cytochrome C class I; KEGG: mex:Mext_1356 cytochrome c class I; cytochrome C class I 1610858 7115166 Mchl_1556 Methylobacterium extorquens CM4 cytochrome C class I YP_002420349.1 1610532 D 440085 CDS YP_002420350.1 218529534 7115167 complement(1610934..1611686) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_1357 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 1611686 7115167 Mchl_1557 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002420350.1 1610934 R 440085 CDS YP_002420351.1 218529535 7115168 complement(1612081..1613706) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1358 ABC transporter; ABC transporter 1613706 7115168 Mchl_1558 Methylobacterium extorquens CM4 ABC transporter YP_002420351.1 1612081 R 440085 CDS YP_002420352.1 218529536 7115169 complement(1613706..1615349) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1359 ABC transporter; ABC transporter 1615349 7115169 Mchl_1559 Methylobacterium extorquens CM4 ABC transporter YP_002420352.1 1613706 R 440085 CDS YP_002420353.1 218529537 7115170 1615449..1617038 1 NC_011757.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: mex:Mext_1360 cytochrome bd ubiquinol oxidase subunit I; cytochrome bd ubiquinol oxidase subunit I 1617038 7115170 Mchl_1560 Methylobacterium extorquens CM4 cytochrome bd ubiquinol oxidase subunit I YP_002420353.1 1615449 D 440085 CDS YP_002420354.1 218529538 7115171 1617100..1618254 1 NC_011757.1 KEGG: mex:Mext_1361 cytochrome d ubiquinol oxidase subunit II; TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 1618254 7115171 Mchl_1561 Methylobacterium extorquens CM4 cytochrome d ubiquinol oxidase subunit II YP_002420354.1 1617100 D 440085 CDS YP_002420355.1 218529539 7115172 1618324..1618455 1 NC_011757.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: mex:Mext_1362 cyd operon protein YbgT; cyd operon protein YbgT 1618455 7115172 Mchl_1562 Methylobacterium extorquens CM4 cyd operon protein YbgT YP_002420355.1 1618324 D 440085 CDS YP_002420356.1 218529540 7115173 complement(1618492..1619244) 1 NC_011757.1 PFAM: regulatory protein DeoR; KEGG: mex:Mext_1363 regulatory protein DeoR; DeoR family transcriptional regulator 1619244 7115173 Mchl_1563 Methylobacterium extorquens CM4 DeoR family transcriptional regulator YP_002420356.1 1618492 R 440085 CDS YP_002420357.1 218529541 7115174 complement(1619395..1620978) 1 NC_011757.1 PFAM: amidase; KEGG: mex:Mext_1364 amidase; amidase 1620978 7115174 Mchl_1564 Methylobacterium extorquens CM4 amidase YP_002420357.1 1619395 R 440085 CDS YP_002420358.1 218529542 7115175 1621497..1623923 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_1365 response regulator receiver; response regulator receiver protein 1623923 7115175 Mchl_1565 Methylobacterium extorquens CM4 response regulator receiver protein YP_002420358.1 1621497 D 440085 CDS YP_002420359.1 218529543 7115176 1624056..1624868 1 NC_011757.1 KEGG: mex:Mext_1366 hypothetical protein; hypothetical protein 1624868 7115176 Mchl_1566 Methylobacterium extorquens CM4 hypothetical protein YP_002420359.1 1624056 D 440085 CDS YP_002420360.1 218529544 7115177 1625197..1627701 1 NC_011757.1 KEGG: mex:Mext_1367 cellulose synthase catalytic subunit (UDP-forming); TIGRFAM: cellulose synthase catalytic subunit (UDP-forming); PFAM: glycosyl transferase family 2; cellulose synthase catalytic subunit 1627701 7115177 Mchl_1567 Methylobacterium extorquens CM4 cellulose synthase catalytic subunit YP_002420360.1 1625197 D 440085 CDS YP_002420361.1 218529545 7115178 1627698..1630340 1 NC_011757.1 PFAM: cellulose synthase subunit B; KEGG: mex:Mext_1368 hypothetical protein; cellulose synthase subunit B 1630340 7115178 Mchl_1568 Methylobacterium extorquens CM4 cellulose synthase subunit B YP_002420361.1 1627698 D 440085 CDS YP_002420362.1 218529546 7115179 1630340..1631629 1 NC_011757.1 PFAM: glycoside hydrolase family 8; KEGG: mex:Mext_1369 cellulase; cellulase 1631629 7115179 Mchl_1569 Methylobacterium extorquens CM4 cellulase YP_002420362.1 1630340 D 440085 CDS YP_002420363.1 218529547 7115180 1631713..1633677 1 NC_011757.1 KEGG: mex:Mext_1370 hypothetical protein; hypothetical protein 1633677 7115180 Mchl_1570 Methylobacterium extorquens CM4 hypothetical protein YP_002420363.1 1631713 D 440085 CDS YP_002420364.1 218529548 7115181 1633674..1634687 1 NC_011757.1 KEGG: mex:Mext_1371 hypothetical protein; hypothetical protein 1634687 7115181 Mchl_1571 Methylobacterium extorquens CM4 hypothetical protein YP_002420364.1 1633674 D 440085 CDS YP_002420365.1 218529549 7118762 1642058..1642321 1 NC_011757.1 KEGG: mpo:Mpop_4257 hypothetical protein; hypothetical protein 1642321 7118762 Mchl_1573 Methylobacterium extorquens CM4 hypothetical protein YP_002420365.1 1642058 D 440085 CDS YP_002420366.1 218529550 7118763 1642414..1642650 1 NC_011757.1 hypothetical protein 1642650 7118763 Mchl_1574 Methylobacterium extorquens CM4 hypothetical protein YP_002420366.1 1642414 D 440085 CDS YP_002420367.1 218529551 7118764 complement(1642729..1643310) 1 NC_011757.1 hypothetical protein 1643310 7118764 Mchl_1575 Methylobacterium extorquens CM4 hypothetical protein YP_002420367.1 1642729 R 440085 CDS YP_002420368.1 218529552 7118765 complement(1643307..1643606) 1 NC_011757.1 hypothetical protein 1643606 7118765 Mchl_1576 Methylobacterium extorquens CM4 hypothetical protein YP_002420368.1 1643307 R 440085 CDS YP_002420369.1 218529553 7118766 complement(1643621..1644049) 1 NC_011757.1 KEGG: pfo:Pfl01_5446 hypothetical protein; hypothetical protein 1644049 7118766 Mchl_1577 Methylobacterium extorquens CM4 hypothetical protein YP_002420369.1 1643621 R 440085 CDS YP_002420370.1 218529554 7118767 complement(1644064..1644627) 1 NC_011757.1 KEGG: mex:Mext_4382 hypothetical protein; hypothetical protein 1644627 7118767 Mchl_1578 Methylobacterium extorquens CM4 hypothetical protein YP_002420370.1 1644064 R 440085 CDS YP_002420371.1 218529555 7118768 complement(1644816..1645514) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_4383 peptidoglycan binding domain-containing protein; peptidoglycan-binding protein 1645514 7118768 Mchl_1579 Methylobacterium extorquens CM4 peptidoglycan-binding protein YP_002420371.1 1644816 R 440085 CDS YP_002420372.1 218529556 7118769 complement(1645999..1649217) 1 NC_011757.1 KEGG: nar:Saro_2740 PE-PGRS family protein; hypothetical protein 1649217 7118769 Mchl_1580 Methylobacterium extorquens CM4 hypothetical protein YP_002420372.1 1645999 R 440085 CDS YP_002420373.1 218529557 7118770 complement(1649333..1649605) 1 NC_011757.1 hypothetical protein 1649605 7118770 Mchl_1581 Methylobacterium extorquens CM4 hypothetical protein YP_002420373.1 1649333 R 440085 CDS YP_002420374.1 218529558 7118771 complement(1649602..1649913) 1 NC_011757.1 hypothetical protein 1649913 7118771 Mchl_1582 Methylobacterium extorquens CM4 hypothetical protein YP_002420374.1 1649602 R 440085 CDS YP_002420375.1 218529559 7118772 complement(1649925..1653914) 1 NC_011757.1 KEGG: mex:Mext_3534 hypothetical protein; hypothetical protein 1653914 7118772 Mchl_1583 Methylobacterium extorquens CM4 hypothetical protein YP_002420375.1 1649925 R 440085 CDS YP_002420376.1 218529560 7118773 complement(1654533..1654931) 1 NC_011757.1 KEGG: mex:Mext_3535 NLP/P60 protein; NLP/P60 protein 1654931 7118773 Mchl_1584 Methylobacterium extorquens CM4 NLP/P60 protein YP_002420376.1 1654533 R 440085 CDS YP_002420377.1 218529561 7118774 complement(1654928..1655476) 1 NC_011757.1 PFAM: Domain of unknown function DUF1833; KEGG: mag:amb0393 hypothetical protein; hypothetical protein 1655476 7118774 Mchl_1585 Methylobacterium extorquens CM4 hypothetical protein YP_002420377.1 1654928 R 440085 CDS YP_002420378.1 218529562 7118775 complement(1655481..1655858) 1 NC_011757.1 hypothetical protein 1655858 7118775 Mchl_1586 Methylobacterium extorquens CM4 hypothetical protein YP_002420378.1 1655481 R 440085 CDS YP_002420379.1 218529563 7118776 complement(1655862..1659719) 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mpo:Mpop_5452 hypothetical protein; lytic transglycosylase 1659719 7118776 Mchl_1587 Methylobacterium extorquens CM4 lytic transglycosylase YP_002420379.1 1655862 R 440085 CDS YP_002420380.1 218529564 7118777 complement(1659726..1659986) 1 NC_011757.1 hypothetical protein 1659986 7118777 Mchl_1588 Methylobacterium extorquens CM4 hypothetical protein YP_002420380.1 1659726 R 440085 CDS YP_002420381.1 218529565 7118778 complement(1660061..1660486) 1 NC_011757.1 hypothetical protein 1660486 7118778 Mchl_1589 Methylobacterium extorquens CM4 hypothetical protein YP_002420381.1 1660061 R 440085 CDS YP_002420382.1 218529566 7118779 complement(1660483..1660677) 1 NC_011757.1 hypothetical protein 1660677 7118779 Mchl_1590 Methylobacterium extorquens CM4 hypothetical protein YP_002420382.1 1660483 R 440085 CDS YP_002420383.1 218529567 7118780 complement(1660674..1661606) 1 NC_011757.1 KEGG: mlo:mlr8533 hypothetical protein; hypothetical protein 1661606 7118780 Mchl_1591 Methylobacterium extorquens CM4 hypothetical protein YP_002420383.1 1660674 R 440085 CDS YP_002420384.1 218529568 7118781 complement(1661645..1662055) 1 NC_011757.1 KEGG: bra:BRADO3637 hypothetical protein; hypothetical protein 1662055 7118781 Mchl_1592 Methylobacterium extorquens CM4 hypothetical protein YP_002420384.1 1661645 R 440085 CDS YP_002420385.1 218529569 7118782 complement(1662057..1662740) 1 NC_011757.1 KEGG: bra:BRADO3636 hypothetical protein; hypothetical protein 1662740 7118782 Mchl_1593 Methylobacterium extorquens CM4 hypothetical protein YP_002420385.1 1662057 R 440085 CDS YP_002420386.1 218529570 7118783 complement(1662740..1663066) 1 NC_011757.1 KEGG: mlo:mlr8530 hypothetical protein; hypothetical protein 1663066 7118783 Mchl_1594 Methylobacterium extorquens CM4 hypothetical protein YP_002420386.1 1662740 R 440085 CDS YP_002420387.1 218529571 7118784 complement(1663063..1663743) 1 NC_011757.1 KEGG: mxa:MXAN_1217 hypothetical protein; hypothetical protein 1663743 7118784 Mchl_1595 Methylobacterium extorquens CM4 hypothetical protein YP_002420387.1 1663063 R 440085 CDS YP_002420388.1 218529572 7118785 complement(1663740..1663925) 1 NC_011757.1 hypothetical protein 1663925 7118785 Mchl_1596 Methylobacterium extorquens CM4 hypothetical protein YP_002420388.1 1663740 R 440085 CDS YP_002420389.1 218529573 7118786 complement(1664063..1664383) 1 NC_011757.1 hypothetical protein 1664383 7118786 Mchl_1597 Methylobacterium extorquens CM4 hypothetical protein YP_002420389.1 1664063 R 440085 CDS YP_002420390.1 218529574 7118787 complement(1664576..1665082) 1 NC_011757.1 hypothetical protein 1665082 7118787 Mchl_1598 Methylobacterium extorquens CM4 hypothetical protein YP_002420390.1 1664576 R 440085 CDS YP_002420391.1 218529575 7118788 complement(1665088..1665348) 1 NC_011757.1 KEGG: ppw:PputW619_1340 hypothetical protein; hypothetical protein 1665348 7118788 Mchl_1599 Methylobacterium extorquens CM4 hypothetical protein YP_002420391.1 1665088 R 440085 CDS YP_002420392.1 218529576 7118789 complement(1665412..1666713) 1 NC_011757.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: major capsid protein HK97; KEGG: bpm:BURPS1710b_1682 HK97 family phage major capsid protein; phage major capsid protein, HK97 family 1666713 7118789 Mchl_1600 Methylobacterium extorquens CM4 phage major capsid protein, HK97 family YP_002420392.1 1665412 R 440085 CDS YP_002420393.1 218529577 7118790 complement(1666725..1667447) 1 NC_011757.1 TIGRFAM: phage prohead protease HK97 family; PFAM: peptidase U35 phage prohead HK97; KEGG: nar:Saro_0648 prohead peptidase; phage prohead protease HK97 family 1667447 7118790 Mchl_1601 Methylobacterium extorquens CM4 phage prohead protease HK97 family YP_002420393.1 1666725 R 440085 CDS YP_002420394.1 218529578 7118791 complement(1667450..1668754) 1 NC_011757.1 TIGRFAM: phage portal protein, HK97 family; PFAM: portal protein; KEGG: bpm:BURPS1710b_1680 HK97 family phage portal protein; phage portal protein, HK97 family 1668754 7118791 Mchl_1602 Methylobacterium extorquens CM4 phage portal protein, HK97 family YP_002420394.1 1667450 R 440085 CDS YP_002420395.1 218529579 7118792 complement(1668774..1670447) 1 NC_011757.1 PFAM: terminase; KEGG: oan:Oant_0238 phage terminase; terminase 1670447 7118792 Mchl_1603 Methylobacterium extorquens CM4 terminase YP_002420395.1 1668774 R 440085 CDS YP_002420396.1 218529580 7118793 complement(1670764..1671345) 1 NC_011757.1 PFAM: terminase small subunit; KEGG: bpt:Bpet0975 hypothetical protein; terminase small subunit 1671345 7118793 Mchl_1604 Methylobacterium extorquens CM4 terminase small subunit YP_002420396.1 1670764 R 440085 CDS YP_002420397.1 218529581 7118794 1671548..1671916 1 NC_011757.1 hypothetical protein 1671916 7118794 Mchl_1605 Methylobacterium extorquens CM4 hypothetical protein YP_002420397.1 1671548 D 440085 CDS YP_002420398.1 218529582 7118795 complement(1671911..1672237) 1 NC_011757.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: mex:Mext_0765 HNH endonuclease; HNH endonuclease 1672237 7118795 Mchl_1606 Methylobacterium extorquens CM4 HNH endonuclease YP_002420398.1 1671911 R 440085 CDS YP_002420399.1 218529583 7118796 1672344..1672985 1 NC_011757.1 KEGG: aby:ABAYE2688 hypothetical protein; hypothetical protein 1672985 7118796 Mchl_1607 Methylobacterium extorquens CM4 hypothetical protein YP_002420399.1 1672344 D 440085 CDS YP_002420400.1 218529584 7118797 1673413..1673646 1 NC_011757.1 KEGG: mex:Mext_3541 hypothetical protein; hypothetical protein 1673646 7118797 Mchl_1608 Methylobacterium extorquens CM4 hypothetical protein YP_002420400.1 1673413 D 440085 CDS YP_002420401.1 218529585 7118798 complement(1673827..1674543) 1 NC_011757.1 hypothetical protein 1674543 7118798 Mchl_1609 Methylobacterium extorquens CM4 hypothetical protein YP_002420401.1 1673827 R 440085 CDS YP_002420402.1 218529586 7118799 complement(1674666..1675103) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mpo:Mpop_2952 MucR family transcriptional regulator; MucR family transcriptional regulator 1675103 7118799 Mchl_1610 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002420402.1 1674666 R 440085 CDS YP_002420403.1 218529587 7118800 complement(1675151..1675420) 1 NC_011757.1 KEGG: bxe:Bxe_A3081 hypothetical protein; hypothetical protein 1675420 7118800 Mchl_1611 Methylobacterium extorquens CM4 hypothetical protein YP_002420403.1 1675151 R 440085 CDS YP_002420404.1 218529588 7118801 complement(1675417..1675626) 1 NC_011757.1 hypothetical protein 1675626 7118801 Mchl_1612 Methylobacterium extorquens CM4 hypothetical protein YP_002420404.1 1675417 R 440085 CDS YP_002420405.1 218529589 7118802 complement(1675626..1675976) 1 NC_011757.1 hypothetical protein 1675976 7118802 Mchl_1613 Methylobacterium extorquens CM4 hypothetical protein YP_002420405.1 1675626 R 440085 CDS YP_002420406.1 218529590 7118803 complement(1675973..1676746) 1 NC_011757.1 KEGG: mpo:Mpop_1343 hypothetical protein; hypothetical protein 1676746 7118803 Mchl_1614 Methylobacterium extorquens CM4 hypothetical protein YP_002420406.1 1675973 R 440085 CDS YP_002420407.1 218529591 7118804 complement(1676804..1677562) 1 NC_011757.1 KEGG: mex:Mext_2440 hypothetical protein; hypothetical protein 1677562 7118804 Mchl_1615 Methylobacterium extorquens CM4 hypothetical protein YP_002420407.1 1676804 R 440085 CDS YP_002420408.1 218529592 7118805 complement(1678232..1678858) 1 NC_011757.1 PFAM: MT-A70 family protein; KEGG: ajs:Ajs_0426 MT-A70 family protein; MT-A70 family protein 1678858 7118805 Mchl_1616 Methylobacterium extorquens CM4 MT-A70 family protein YP_002420408.1 1678232 R 440085 CDS YP_002420409.1 218529593 7118806 complement(1678837..1679049) 1 NC_011757.1 KEGG: met:M446_4099 hypothetical protein; hypothetical protein 1679049 7118806 Mchl_1617 Methylobacterium extorquens CM4 hypothetical protein YP_002420409.1 1678837 R 440085 CDS YP_002420410.1 218529594 7118807 complement(1679042..1679245) 1 NC_011757.1 hypothetical protein 1679245 7118807 Mchl_1618 Methylobacterium extorquens CM4 hypothetical protein YP_002420410.1 1679042 R 440085 CDS YP_002420411.1 218529595 7118808 complement(1679242..1679799) 1 NC_011757.1 PFAM: endodeoxyribonuclease RusA; KEGG: mex:Mext_2442 hypothetical protein; endodeoxyribonuclease RusA 1679799 7118808 Mchl_1619 Methylobacterium extorquens CM4 endodeoxyribonuclease RusA YP_002420411.1 1679242 R 440085 CDS YP_002420412.1 218529596 7118809 complement(1679805..1680074) 1 NC_011757.1 KEGG: mpo:Mpop_2872 hypothetical protein; hypothetical protein 1680074 7118809 Mchl_1620 Methylobacterium extorquens CM4 hypothetical protein YP_002420412.1 1679805 R 440085 CDS YP_002420413.1 218529597 7118810 complement(1680187..1680609) 1 NC_011757.1 KEGG: mrd:Mrad2831_5725 hypothetical protein; hypothetical protein 1680609 7118810 Mchl_1621 Methylobacterium extorquens CM4 hypothetical protein YP_002420413.1 1680187 R 440085 CDS YP_002420414.1 218529598 7118811 1680885..1681133 1 NC_011757.1 hypothetical protein 1681133 7118811 Mchl_1622 Methylobacterium extorquens CM4 hypothetical protein YP_002420414.1 1680885 D 440085 CDS YP_002420415.1 218529599 7118812 complement(1681234..1681722) 1 NC_011757.1 hypothetical protein 1681722 7118812 Mchl_1623 Methylobacterium extorquens CM4 hypothetical protein YP_002420415.1 1681234 R 440085 CDS YP_002420416.1 218529600 7118813 complement(1681719..1681871) 1 NC_011757.1 hypothetical protein 1681871 7118813 Mchl_1624 Methylobacterium extorquens CM4 hypothetical protein YP_002420416.1 1681719 R 440085 CDS YP_002420417.1 218529601 7118814 complement(1681868..1682101) 1 NC_011757.1 KEGG: bja:bll5480 chaperone; chaperone 1682101 7118814 Mchl_1625 Methylobacterium extorquens CM4 chaperone YP_002420417.1 1681868 R 440085 CDS YP_002420418.1 218529602 7118815 1682198..1682932 1 NC_011757.1 PFAM: helix-turn-helix domain protein; peptidase S24 and S26 domain protein; KEGG: atc:AGR_C_784 hypothetical protein; phage repressor 1682932 7118815 Mchl_1626 Methylobacterium extorquens CM4 phage repressor YP_002420418.1 1682198 D 440085 CDS YP_002420419.1 218529603 7118816 1682934..1683242 1 NC_011757.1 hypothetical protein 1683242 7118816 Mchl_1627 Methylobacterium extorquens CM4 hypothetical protein YP_002420419.1 1682934 D 440085 CDS YP_002420420.1 218529604 7118817 complement(1683708..1683965) 1 NC_011757.1 KEGG: mrd:Mrad2831_5731 hypothetical protein; hypothetical protein 1683965 7118817 Mchl_1628 Methylobacterium extorquens CM4 hypothetical protein YP_002420420.1 1683708 R 440085 CDS YP_002420421.1 218529605 7118818 1684411..1684872 1 NC_011757.1 KEGG: mex:Mext_1589 hypothetical protein; hypothetical protein 1684872 7118818 Mchl_1629 Methylobacterium extorquens CM4 hypothetical protein YP_002420421.1 1684411 D 440085 CDS YP_002420422.1 218529606 7118819 1684937..1685443 1 NC_011757.1 hypothetical protein 1685443 7118819 Mchl_1630 Methylobacterium extorquens CM4 hypothetical protein YP_002420422.1 1684937 D 440085 CDS YP_002420423.1 218529607 7118820 1685450..1685731 1 NC_011757.1 hypothetical protein 1685731 7118820 Mchl_1631 Methylobacterium extorquens CM4 hypothetical protein YP_002420423.1 1685450 D 440085 CDS YP_002420424.1 218529608 7118821 1685731..1686021 1 NC_011757.1 hypothetical protein 1686021 7118821 Mchl_1632 Methylobacterium extorquens CM4 hypothetical protein YP_002420424.1 1685731 D 440085 CDS YP_002420425.1 218529609 7118822 1686018..1686227 1 NC_011757.1 hypothetical protein 1686227 7118822 Mchl_1633 Methylobacterium extorquens CM4 hypothetical protein YP_002420425.1 1686018 D 440085 CDS YP_002420426.1 218529610 7118823 1686224..1686655 1 NC_011757.1 KEGG: mrd:Mrad2831_1232 HNH nuclease; hypothetical protein 1686655 7118823 Mchl_1634 Methylobacterium extorquens CM4 hypothetical protein YP_002420426.1 1686224 D 440085 CDS YP_002420427.1 218529611 7118824 1686659..1687009 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: nfa:nfa22390 transcriptional regulator; XRE family transcriptional regulator 1687009 7118824 Mchl_1635 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002420427.1 1686659 D 440085 CDS YP_002420428.1 218529612 7118825 1687003..1687398 1 NC_011757.1 hypothetical protein 1687398 7118825 Mchl_1636 Methylobacterium extorquens CM4 hypothetical protein YP_002420428.1 1687003 D 440085 CDS YP_002420429.1 218529613 7118826 1688402..1688716 1 NC_011757.1 KEGG: rxy:Rxyl_0105 quinolinate synthetase; hypothetical protein 1688716 7118826 Mchl_1637 Methylobacterium extorquens CM4 hypothetical protein YP_002420429.1 1688402 D 440085 CDS YP_002420430.1 218529614 7118827 1688713..1689237 1 NC_011757.1 KEGG: dac:Daci_3228 hypothetical protein; hypothetical protein 1689237 7118827 Mchl_1638 Methylobacterium extorquens CM4 hypothetical protein YP_002420430.1 1688713 D 440085 CDS YP_002420431.1 218529615 7118828 1689234..1690466 1 NC_011757.1 hypothetical protein 1690466 7118828 Mchl_1639 Methylobacterium extorquens CM4 hypothetical protein YP_002420431.1 1689234 D 440085 CDS YP_002420432.1 218529616 7118829 1690468..1690716 1 NC_011757.1 hypothetical protein 1690716 7118829 Mchl_1640 Methylobacterium extorquens CM4 hypothetical protein YP_002420432.1 1690468 D 440085 CDS YP_002420433.1 218529617 7118830 1690713..1691324 1 NC_011757.1 KEGG: mucin-associated surface protein (MASP); hypothetical protein 1691324 7118830 Mchl_1641 Methylobacterium extorquens CM4 hypothetical protein YP_002420433.1 1690713 D 440085 CDS YP_002420434.1 218529618 7118831 1691325..1691660 1 NC_011757.1 hypothetical protein 1691660 7118831 Mchl_1642 Methylobacterium extorquens CM4 hypothetical protein YP_002420434.1 1691325 D 440085 CDS YP_002420435.1 218529619 7118832 1691653..1692015 1 NC_011757.1 KEGG: hypothetical protein; hypothetical protein 1692015 7118832 Mchl_1643 Methylobacterium extorquens CM4 hypothetical protein YP_002420435.1 1691653 D 440085 CDS YP_002420436.1 218529620 7118833 1692008..1692283 1 NC_011757.1 hypothetical protein 1692283 7118833 Mchl_1644 Methylobacterium extorquens CM4 hypothetical protein YP_002420436.1 1692008 D 440085 CDS YP_002420437.1 218529621 7118834 1692280..1692621 1 NC_011757.1 KEGG: bja:bll8082 hypothetical protein; hypothetical protein 1692621 7118834 Mchl_1645 Methylobacterium extorquens CM4 hypothetical protein YP_002420437.1 1692280 D 440085 CDS YP_002420438.1 218529622 7118835 1692687..1693679 1 NC_011757.1 PFAM: integrase family protein; KEGG: mrd:Mrad2831_4162 integrase family protein; integrase family protein 1693679 7118835 Mchl_1646 Methylobacterium extorquens CM4 integrase family protein YP_002420438.1 1692687 D 440085 CDS YP_002420439.1 218529623 7118837 1694938..1695207 1 NC_011757.1 hypothetical protein 1695207 7118837 Mchl_1648 Methylobacterium extorquens CM4 hypothetical protein YP_002420439.1 1694938 D 440085 CDS YP_002420440.1 218529624 7118838 complement(1695539..1696309) 1 NC_011757.1 KEGG: mex:Mext_1375 hypothetical protein; transmembrane anti-sigma factor 1696309 7118838 Mchl_1649 Methylobacterium extorquens CM4 transmembrane anti-sigma factor YP_002420440.1 1695539 R 440085 CDS YP_002420441.1 218529625 7116794 complement(1696395..1696958) 1 NC_011757.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; possibly involved in prevention of copper toxicity; RNA polymerase sigma factor 1696958 7116794 Mchl_1650 Methylobacterium extorquens CM4 RNA polymerase sigma factor YP_002420441.1 1696395 R 440085 CDS YP_002420442.1 218529626 7116796 complement(1697196..1698500) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_1377 peptidoglycan binding domain-containing protein; ErfK/YbiS/YcfS/YnhG family protein 1698500 7116796 Mchl_1651 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002420442.1 1697196 R 440085 CDS YP_002420443.1 218529627 7116797 1698785..1699198 1 NC_011757.1 KEGG: mpo:Mpop_1372 hypothetical protein; hypothetical protein 1699198 7116797 Mchl_1652 Methylobacterium extorquens CM4 hypothetical protein YP_002420443.1 1698785 D 440085 CDS YP_002420444.1 218529628 7116798 1699248..1700321 1 NC_011757.1 PFAM: protein of unknown function DUF461; nuclear export factor GLE1; KEGG: mex:Mext_1378 hypothetical protein; hypothetical protein 1700321 7116798 Mchl_1653 Methylobacterium extorquens CM4 hypothetical protein YP_002420444.1 1699248 D 440085 CDS YP_002420445.1 218529629 7116799 1700437..1700961 1 NC_011757.1 PFAM: protein of unknown function DUF461; KEGG: mex:Mext_1379 hypothetical protein; hypothetical protein 1700961 7116799 Mchl_1654 Methylobacterium extorquens CM4 hypothetical protein YP_002420445.1 1700437 D 440085 CDS YP_002420446.1 218529630 7116800 1700951..1701598 1 NC_011757.1 PFAM: electron transporter SCO1/SenC; KEGG: mex:Mext_1380 electron transporter SCO1/SenC; electron transporter SCO1/SenC 1701598 7116800 Mchl_1655 Methylobacterium extorquens CM4 electron transporter SCO1/SenC YP_002420446.1 1700951 D 440085 CDS YP_002420447.1 218529631 7116801 1701741..1702097 1 NC_011757.1 KEGG: mex:Mext_1381 hypothetical protein; hypothetical protein 1702097 7116801 Mchl_1656 Methylobacterium extorquens CM4 hypothetical protein YP_002420447.1 1701741 D 440085 CDS YP_002420448.1 218529632 7116802 1702140..1704287 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_1382 TonB-dependent receptor; TonB-dependent receptor 1704287 7116802 Mchl_1657 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002420448.1 1702140 D 440085 CDS YP_002420449.1 218529633 7116803 1704532..1706379 1 NC_011757.1 PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: mex:Mext_1383 peptidase C14 caspase catalytic subunit P20; peptidase C14 caspase catalytic subunit p20 1706379 7116803 Mchl_1658 Methylobacterium extorquens CM4 peptidase C14 caspase catalytic subunit p20 YP_002420449.1 1704532 D 440085 CDS YP_002420450.1 218529634 7116804 complement(1706530..1708002) 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_1384 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 1708002 7116804 Mchl_1659 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002420450.1 1706530 R 440085 CDS YP_002420451.1 218529635 7116805 complement(1708107..1708778) 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_1385 GntR domain-containing protein; GntR family transcriptional regulator 1708778 7116805 Mchl_1660 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002420451.1 1708107 R 440085 CDS YP_002420452.1 218529636 7116806 1708942..1709964 1 NC_011757.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: mex:Mext_1386 TRAP dicarboxylate transporter-DctP subunit; TRAP dicarboxylate transporter subunit DctP 1709964 7116806 Mchl_1661 Methylobacterium extorquens CM4 TRAP dicarboxylate transporter subunit DctP YP_002420452.1 1708942 D 440085 CDS YP_002420453.1 218529637 7116807 1709961..1710686 1 NC_011757.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: mex:Mext_1387 tripartite ATP-independent periplasmic transporter DctQ; tripartite ATP-independent periplasmic transporter DctQ component 1710686 7116807 Mchl_1662 Methylobacterium extorquens CM4 tripartite ATP-independent periplasmic transporter DctQ component YP_002420453.1 1709961 D 440085 CDS YP_002420454.1 218529638 7116808 1710683..1712035 1 NC_011757.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: mex:Mext_1388 TRAP dicarboxylate transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM 1712035 7116808 Mchl_1663 Methylobacterium extorquens CM4 TRAP dicarboxylate transporter subunit DctM YP_002420454.1 1710683 D 440085 CDS YP_002420455.1 218529639 7116809 1712203..1712400 1 NC_011757.1 KEGG: mex:Mext_1389 hypothetical protein; hypothetical protein 1712400 7116809 Mchl_1664 Methylobacterium extorquens CM4 hypothetical protein YP_002420455.1 1712203 D 440085 CDS YP_002420456.1 218529640 7116810 1713193..1713426 1 NC_011757.1 KEGG: mex:Mext_1390 hypothetical protein; hypothetical protein 1713426 7116810 Mchl_1665 Methylobacterium extorquens CM4 hypothetical protein YP_002420456.1 1713193 D 440085 CDS YP_002420457.1 218529641 7116811 1713494..1714540 1 NC_011757.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mex:Mext_1391 pyridoxal-5'-phosphate-dependent protein beta subunit; pyridoxal-5'-phosphate-dependent protein subunit beta 1714540 7116811 Mchl_1666 Methylobacterium extorquens CM4 pyridoxal-5'-phosphate-dependent protein subunit beta YP_002420457.1 1713494 D 440085 CDS YP_002420458.1 218529642 7116812 1714653..1714808 1 NC_011757.1 KEGG: mex:Mext_1392 hypothetical protein; hypothetical protein 1714808 7116812 Mchl_1667 Methylobacterium extorquens CM4 hypothetical protein YP_002420458.1 1714653 D 440085 CDS YP_002420459.1 218529643 7116813 complement(1714824..1716326) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_1393 peptidoglycan binding domain-containing protein; peptidoglycan-binding protein 1716326 7116813 Mchl_1668 Methylobacterium extorquens CM4 peptidoglycan-binding protein YP_002420459.1 1714824 R 440085 CDS YP_002420460.1 218529644 7116814 1716404..1716940 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_1394 hypothetical protein; hypothetical protein 1716940 7116814 Mchl_1669 Methylobacterium extorquens CM4 hypothetical protein YP_002420460.1 1716404 D 440085 CDS YP_002420461.1 218529645 7116815 1717053..1722371 1 NC_011757.1 PFAM: alpha-2-macroglobulin; alpha-2-macroglobulin 2; KEGG: mex:Mext_1395 alpha-2-macroglobulin domain-containing protein; alpha-2-macroglobulin 1722371 7116815 Mchl_1670 Methylobacterium extorquens CM4 alpha-2-macroglobulin YP_002420461.1 1717053 D 440085 CDS YP_002420462.1 218529646 7116816 1722376..1724577 1 NC_011757.1 TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: mex:Mext_1396 penicillin-binding protein 1C; penicillin-binding protein 1C 1724577 7116816 Mchl_1671 Methylobacterium extorquens CM4 penicillin-binding protein 1C YP_002420462.1 1722376 D 440085 CDS YP_002420463.1 218529647 7116817 1724715..1725035 1 NC_011757.1 PFAM: small multidrug resistance protein; KEGG: mex:Mext_1397 small multidrug resistance protein; small multidrug resistance protein 1725035 7116817 Mchl_1672 Methylobacterium extorquens CM4 small multidrug resistance protein YP_002420463.1 1724715 D 440085 CDS YP_002420464.1 218529648 7116818 complement(1725040..1725840) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_1398 helix-turn-helix domain-containing protein; helix-turn-helix domain-containing protein 1725840 7116818 Mchl_1673 Methylobacterium extorquens CM4 helix-turn-helix domain-containing protein YP_002420464.1 1725040 R 440085 CDS YP_002420465.1 218529649 7116819 complement(1725892..1726515) 1 NC_011757.1 TIGRFAM: sortase family protein; PFAM: peptidase C60 sortase A and B; KEGG: mex:Mext_1399 sortase family protein; sortase family protein 1726515 7116819 Mchl_1674 Methylobacterium extorquens CM4 sortase family protein YP_002420465.1 1725892 R 440085 CDS YP_002420466.1 218529650 7116820 complement(1726512..1728728) 1 NC_011757.1 PFAM: von Willebrand factor type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: mex:Mext_1400 vault protein inter-alpha-trypsin subunit; Vault protein inter-alpha-trypsin domain-containing protein 1728728 7116820 Mchl_1675 Methylobacterium extorquens CM4 Vault protein inter-alpha-trypsin domain-containing protein YP_002420466.1 1726512 R 440085 CDS YP_002420467.1 218529651 7116821 1728973..1729584 1 NC_011757.1 PFAM: phosphoglycerate mutase; KEGG: mex:Mext_1401 phosphoglycerate mutase; phosphoglycerate mutase 1729584 7116821 Mchl_1676 Methylobacterium extorquens CM4 phosphoglycerate mutase YP_002420467.1 1728973 D 440085 CDS YP_002420468.1 218529652 7116822 complement(1729672..1730484) 1 NC_011757.1 KEGG: mex:Mext_1402 hypothetical protein; hypothetical protein 1730484 7116822 Mchl_1677 Methylobacterium extorquens CM4 hypothetical protein YP_002420468.1 1729672 R 440085 CDS YP_002420469.1 218529653 7116823 complement(1730523..1731536) 1 NC_011757.1 PFAM: high-affinity nickel-transporter; KEGG: mex:Mext_1403 high-affinity nickel-transporter; high-affinity nickel-transporter 1731536 7116823 Mchl_1678 Methylobacterium extorquens CM4 high-affinity nickel-transporter YP_002420469.1 1730523 R 440085 CDS YP_002420470.1 218529654 7116824 complement(1731527..1732204) 1 NC_011757.1 PFAM: protein of unknown function DUF1007; KEGG: mex:Mext_1404 hypothetical protein; hypothetical protein 1732204 7116824 Mchl_1679 Methylobacterium extorquens CM4 hypothetical protein YP_002420470.1 1731527 R 440085 CDS YP_002420471.1 218529655 7116825 complement(1732319..1732780) 1 NC_011757.1 PFAM: cytochrome C biogenesis protein; KEGG: mex:Mext_1405 cytochrome C biogenesis protein; cytochrome C biogenesis protein 1732780 7116825 Mchl_1680 Methylobacterium extorquens CM4 cytochrome C biogenesis protein YP_002420471.1 1732319 R 440085 CDS YP_002420472.1 218529656 7116826 complement(1732777..1734777) 1 NC_011757.1 PFAM: cytochrome C assembly protein; KEGG: mex:Mext_1406 cytochrome C assembly protein; cytochrome C assembly protein 1734777 7116826 Mchl_1681 Methylobacterium extorquens CM4 cytochrome C assembly protein YP_002420472.1 1732777 R 440085 CDS YP_002420473.1 218529657 7116827 complement(1734824..1735345) 1 NC_011757.1 PFAM: CcmE/CycJ protein; KEGG: mex:Mext_1407 CcmE/CycJ protein; CcmE/CycJ protein 1735345 7116827 Mchl_1682 Methylobacterium extorquens CM4 CcmE/CycJ protein YP_002420473.1 1734824 R 440085 CDS YP_002420474.1 218529658 7116828 complement(1735508..1737079) 1 NC_011757.1 TIGRFAM: cytochrome C biogenesis protein CcmI; KEGG: mex:Mext_1408 cytochrome C biogenesis protein CcmI; cytochrome C biogenesis protein CcmI 1737079 7116828 Mchl_1683 Methylobacterium extorquens CM4 cytochrome C biogenesis protein CcmI YP_002420474.1 1735508 R 440085 CDS YP_002420475.1 218529659 7116829 complement(1737226..1738641) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: mex:Mext_1409 ATPase domain-containing protein; histidine kinase 1738641 7116829 Mchl_1684 Methylobacterium extorquens CM4 histidine kinase YP_002420475.1 1737226 R 440085 CDS YP_002420476.1 218529660 7116830 complement(1739028..1739705) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_1411 response regulator receiver; transcriptional regulator 1739705 7116830 Mchl_1685 Methylobacterium extorquens CM4 transcriptional regulator YP_002420476.1 1739028 R 440085 CDS YP_002420477.1 218529661 7116831 complement(1739744..1740283) 1 NC_011757.1 KEGG: mex:Mext_1412 hypothetical protein; hypothetical protein 1740283 7116831 Mchl_1686 Methylobacterium extorquens CM4 hypothetical protein YP_002420477.1 1739744 R 440085 CDS YP_002420478.1 218529662 7116832 complement(1740297..1740545) 1 NC_011757.1 KEGG: mex:Mext_1413 hypothetical protein; hypothetical protein 1740545 7116832 Mchl_1687 Methylobacterium extorquens CM4 hypothetical protein YP_002420478.1 1740297 R 440085 CDS YP_002420479.1 218529663 7116833 complement(1740568..1740921) 1 NC_011757.1 KEGG: mex:Mext_1414 hypothetical protein; hypothetical protein 1740921 7116833 Mchl_1688 Methylobacterium extorquens CM4 hypothetical protein YP_002420479.1 1740568 R 440085 CDS YP_002420480.1 218529664 7116834 complement(1740971..1741573) 1 NC_011757.1 KEGG: mex:Mext_1415 hypothetical protein; hypothetical protein 1741573 7116834 Mchl_1689 Methylobacterium extorquens CM4 hypothetical protein YP_002420480.1 1740971 R 440085 CDS YP_002420481.1 218529665 7116835 complement(1741607..1742170) 1 NC_011757.1 PFAM: glycoside hydrolase family 24; KEGG: mex:Mext_1416 glycoside hydrolase family protein; glycoside hydrolase family protein 1742170 7116835 Mchl_1690 Methylobacterium extorquens CM4 glycoside hydrolase family protein YP_002420481.1 1741607 R 440085 CDS YP_002420482.1 218529666 7116836 complement(1742289..1743371) 1 NC_011757.1 KEGG: mex:Mext_1417 hypothetical protein; hypothetical protein 1743371 7116836 Mchl_1691 Methylobacterium extorquens CM4 hypothetical protein YP_002420482.1 1742289 R 440085 CDS YP_002420483.1 218529667 7116837 complement(1743396..1747304) 1 NC_011757.1 KEGG: mex:Mext_1418 gene transfer agent (GTA) orfg15, like protein; gene transfer agent (GTA) orfg15,-like protein 1747304 7116837 Mchl_1692 Methylobacterium extorquens CM4 gene transfer agent (GTA) orfg15,-like protein YP_002420483.1 1743396 R 440085 CDS YP_002420484.1 218529668 7116838 complement(1747344..1747808) 1 NC_011757.1 TIGRFAM: phage cell wall peptidase, NlpC/P60 family; KEGG: mex:Mext_1419 NlpC/P60 family phage cell wall peptidase; phage cell wall peptidase, NlpC/P60 family 1747808 7116838 Mchl_1693 Methylobacterium extorquens CM4 phage cell wall peptidase, NlpC/P60 family YP_002420484.1 1747344 R 440085 CDS YP_002420485.1 218529669 7116839 complement(1747816..1748709) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1420 hypothetical protein; hypothetical protein 1748709 7116839 Mchl_1694 Methylobacterium extorquens CM4 hypothetical protein YP_002420485.1 1747816 R 440085 CDS YP_002420486.1 218529670 7116840 complement(1748720..1749361) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1421 hypothetical protein; hypothetical protein 1749361 7116840 Mchl_1695 Methylobacterium extorquens CM4 hypothetical protein YP_002420486.1 1748720 R 440085 CDS YP_002420487.1 218529671 7116841 complement(1749373..1749999) 1 NC_011757.1 KEGG: mex:Mext_1422 gene transfer agent (GTA) orfg11; gene transfer agent (GTA) orfg11 1749999 7116841 Mchl_1696 Methylobacterium extorquens CM4 gene transfer agent (GTA) orfg11 YP_002420487.1 1749373 R 440085 CDS YP_002420488.1 218529672 7116842 complement(1749999..1750229) 1 NC_011757.1 KEGG: mex:Mext_1423 hypothetical protein; hypothetical protein 1750229 7116842 Mchl_1697 Methylobacterium extorquens CM4 hypothetical protein YP_002420488.1 1749999 R 440085 CDS YP_002420489.1 218529673 7116843 complement(1750226..1750558) 1 NC_011757.1 KEGG: mex:Mext_1424 gene transfer agent (GTA) orfg10; gene transfer agent (GTA) orfg10 1750558 7116843 Mchl_1698 Methylobacterium extorquens CM4 gene transfer agent (GTA) orfg10 YP_002420489.1 1750226 R 440085 CDS YP_002420490.1 218529674 7116844 complement(1750555..1750965) 1 NC_011757.1 TIGRFAM: phage major tail protein, TP901-1 family; PFAM: major tail protein TP901-1; KEGG: mex:Mext_1425 TP901-1 family phage major tail protein; phage major tail protein, TP901-1 family 1750965 7116844 Mchl_1699 Methylobacterium extorquens CM4 phage major tail protein, TP901-1 family YP_002420490.1 1750555 R 440085 CDS YP_002420491.1 218529675 7116845 complement(1750995..1751411) 1 NC_011757.1 KEGG: mex:Mext_1426 hypothetical protein; hypothetical protein 1751411 7116845 Mchl_1700 Methylobacterium extorquens CM4 hypothetical protein YP_002420491.1 1750995 R 440085 CDS YP_002420492.1 218529676 7116846 complement(1751411..1751752) 1 NC_011757.1 TIGRFAM: phage head-tail adaptor; PFAM: head-tail adaptor protein; KEGG: mex:Mext_1427 phage head-tail adaptor; phage head-tail adaptor 1751752 7116846 Mchl_1701 Methylobacterium extorquens CM4 phage head-tail adaptor YP_002420492.1 1751411 R 440085 CDS YP_002420493.1 218529677 7116847 complement(1751775..1752350) 1 NC_011757.1 KEGG: mex:Mext_1428 phiE125 gp8 family protein; phiE125 gp8 family protein 1752350 7116847 Mchl_1702 Methylobacterium extorquens CM4 phiE125 gp8 family protein YP_002420493.1 1751775 R 440085 CDS YP_002420494.1 218529678 7116848 1752384..1753139 1 NC_011757.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mex:Mext_1429 peptidase S1 and S6 chymotrypsin/Hap; peptidase S1 and S6 chymotrypsin/Hap 1753139 7116848 Mchl_1703 Methylobacterium extorquens CM4 peptidase S1 and S6 chymotrypsin/Hap YP_002420494.1 1752384 D 440085 CDS YP_002420495.1 218529679 7116849 1753287..1754135 1 NC_011757.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mex:Mext_1430 peptidase S1 and S6 chymotrypsin/Hap; peptidase S1 and S6 chymotrypsin/Hap 1754135 7116849 Mchl_1704 Methylobacterium extorquens CM4 peptidase S1 and S6 chymotrypsin/Hap YP_002420495.1 1753287 D 440085 CDS YP_002420496.1 218529680 7116850 complement(1754142..1755407) 1 NC_011757.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: major capsid protein HK97; KEGG: mex:Mext_1431 HK97 family phage major capsid protein; phage major capsid protein, HK97 family 1755407 7116850 Mchl_1705 Methylobacterium extorquens CM4 phage major capsid protein, HK97 family YP_002420496.1 1754142 R 440085 CDS YP_002420497.1 218529681 7116851 complement(1755440..1755910) 1 NC_011757.1 TIGRFAM: phage prohead protease HK97 family; PFAM: peptidase U35 phage prohead HK97; KEGG: mex:Mext_1432 HK97 family phage prohead protease; phage prohead protease HK97 family 1755910 7116851 Mchl_1706 Methylobacterium extorquens CM4 phage prohead protease HK97 family YP_002420497.1 1755440 R 440085 CDS YP_002420498.1 218529682 7116852 complement(1755968..1757140) 1 NC_011757.1 TIGRFAM: phage portal protein, HK97 family; PFAM: portal protein; KEGG: mex:Mext_1433 HK97 family phage portal protein; phage portal protein, HK97 family 1757140 7116852 Mchl_1707 Methylobacterium extorquens CM4 phage portal protein, HK97 family YP_002420498.1 1755968 R 440085 CDS YP_002420499.1 218529683 7116853 complement(1757187..1758452) 1 NC_011757.1 PFAM: protein of unknown function DUF264; KEGG: mex:Mext_1434 hypothetical protein; hypothetical protein 1758452 7116853 Mchl_1708 Methylobacterium extorquens CM4 hypothetical protein YP_002420499.1 1757187 R 440085 CDS YP_002420500.1 218529684 7116854 complement(1758415..1758843) 1 NC_011757.1 KEGG: mpo:Mpop_1431 hypothetical protein; hypothetical protein 1758843 7116854 Mchl_1709 Methylobacterium extorquens CM4 hypothetical protein YP_002420500.1 1758415 R 440085 CDS YP_002420501.1 218529685 7116855 complement(1759269..1760030) 1 NC_011757.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mex:Mext_1435 precorrin-3B C17-methyltransferase; precorrin-3B C17-methyltransferase 1760030 7116855 Mchl_1710 Methylobacterium extorquens CM4 precorrin-3B C17-methyltransferase YP_002420501.1 1759269 R 440085 CDS YP_002420502.1 218529686 7116856 complement(1760027..1760824) 1 NC_011757.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mex:Mext_1436 precorrin-2 C20-methyltransferase; precorrin-2 C20-methyltransferase 1760824 7116856 Mchl_1711 Methylobacterium extorquens CM4 precorrin-2 C20-methyltransferase YP_002420502.1 1760027 R 440085 CDS YP_002420503.1 218529687 7116857 complement(1760824..1761456) 1 NC_011757.1 PFAM: precorrin-8X methylmutase CbiC/CobH; KEGG: mex:Mext_1437 precorrin-8X methylmutase; precorrin-8X methylmutase 1761456 7116857 Mchl_1712 Methylobacterium extorquens CM4 precorrin-8X methylmutase YP_002420503.1 1760824 R 440085 CDS YP_002420504.1 218529688 7116858 complement(1761463..1762749) 1 NC_011757.1 TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: mex:Mext_1438 precorrin-3B synthase; precorrin-3B synthase 1762749 7116858 Mchl_1713 Methylobacterium extorquens CM4 precorrin-3B synthase YP_002420504.1 1761463 R 440085 CDS YP_002420505.1 218529689 7116859 complement(1762746..1766177) 1 NC_011757.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1766177 cobN 7116859 cobN Methylobacterium extorquens CM4 cobaltochelatase subunit CobN YP_002420505.1 1762746 R 440085 CDS YP_002420506.1 218529690 7116860 complement(1766191..1767087) 1 NC_011757.1 KEGG: mex:Mext_1440 hypothetical protein; hypothetical protein 1767087 7116860 Mchl_1715 Methylobacterium extorquens CM4 hypothetical protein YP_002420506.1 1766191 R 440085 CDS YP_002420507.1 218529691 7116861 complement(1767084..1768118) 1 NC_011757.1 TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: mex:Mext_1441 cobalamin biosynthesis protein CobW; cobalamin biosynthesis protein CobW 1768118 7116861 Mchl_1716 Methylobacterium extorquens CM4 cobalamin biosynthesis protein CobW YP_002420507.1 1767084 R 440085 CDS YP_002420508.1 218529692 7116862 complement(1768115..1768579) 1 NC_011757.1 PFAM: protein of unknown function DUF1636; KEGG: mex:Mext_1442 hypothetical protein; hypothetical protein 1768579 7116862 Mchl_1717 Methylobacterium extorquens CM4 hypothetical protein YP_002420508.1 1768115 R 440085 CDS YP_002420509.1 218529693 7116863 complement(1768566..1769333) 1 NC_011757.1 TIGRFAM: cobalt transporter subunit CbtA; PFAM: Cobalt transporter subunit CbtA KEGG: mex:Mext_1443 cobalt transporter subunit CbtA; cobalt transporter subunit CbtA 1769333 7116863 Mchl_1718 Methylobacterium extorquens CM4 cobalt transporter subunit CbtA YP_002420509.1 1768566 R 440085 CDS YP_002420510.1 218529694 7116864 complement(1769364..1769546) 1 NC_011757.1 TIGRFAM: cobalt transporter subunit CbtB; PFAM: Cobalt transporter subunit CbtB KEGG: mex:Mext_1444 cobalt transporter subunit CbtB; cobalt transporter subunit CbtB 1769546 7116864 Mchl_1719 Methylobacterium extorquens CM4 cobalt transporter subunit CbtB YP_002420510.1 1769364 R 440085 CDS YP_002420511.1 218529695 7116865 complement(1769831..1770253) 1 NC_011757.1 KEGG: mex:Mext_1445 hypothetical protein; hypothetical protein 1770253 7116865 Mchl_1720 Methylobacterium extorquens CM4 hypothetical protein YP_002420511.1 1769831 R 440085 CDS YP_002420512.1 218529696 7116866 complement(1770240..1770731) 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_1446 regulatory protein MarR; MarR family transcriptional regulator 1770731 7116866 Mchl_1721 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002420512.1 1770240 R 440085 CDS YP_002420513.1 218529697 7116867 1770813..1771343 1 NC_011757.1 PFAM: cobalbumin biosynthesis protein; KEGG: mex:Mext_1447 adenosylcobinamide-phosphate guanylyltransferase; adenosylcobinamide-phosphate guanylyltransferase 1771343 7116867 Mchl_1722 Methylobacterium extorquens CM4 adenosylcobinamide-phosphate guanylyltransferase YP_002420513.1 1770813 D 440085 CDS YP_002420514.1 218529698 7116868 1771343..1771945 1 NC_011757.1 KEGG: mex:Mext_1448 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; cob(I)alamin adenosyltransferase 1771945 7116868 Mchl_1723 Methylobacterium extorquens CM4 cob(I)alamin adenosyltransferase YP_002420514.1 1771343 D 440085 CDS YP_002420515.1 218529699 7116869 1772512..1774053 1 NC_011757.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1774053 fumC 7116869 fumC Methylobacterium extorquens CM4 fumarate hydratase YP_002420515.1 1772512 D 440085 CDS YP_002420516.1 218529700 7116870 complement(1774168..1774707) 1 NC_011757.1 TIGRFAM: formaldehyde-activating enzyme; PFAM: formaldehyde-activating enzyme (Fae); KEGG: mex:Mext_1450 formaldehyde-activating enzyme; formaldehyde-activating enzyme 1774707 7116870 Mchl_1725 Methylobacterium extorquens CM4 formaldehyde-activating enzyme YP_002420516.1 1774168 R 440085 CDS YP_002420517.1 218529701 7116871 1774888..1775169 1 NC_011757.1 KEGG: mex:Mext_1451 hypothetical protein; hypothetical protein 1775169 7116871 Mchl_1726 Methylobacterium extorquens CM4 hypothetical protein YP_002420517.1 1774888 D 440085 CDS YP_002420518.1 218529702 7116872 complement(1775193..1775639) 1 NC_011757.1 KEGG: mex:Mext_1452 hypothetical protein; hypothetical protein 1775639 7116872 Mchl_1727 Methylobacterium extorquens CM4 hypothetical protein YP_002420518.1 1775193 R 440085 CDS YP_002420519.1 218529703 7116873 1775860..1776744 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_1453 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 1776744 7116873 Mchl_1728 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002420519.1 1775860 D 440085 CDS YP_002420520.1 218529704 7116874 1777040..1779121 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_1454 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1779121 7116874 Mchl_1729 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002420520.1 1777040 D 440085 CDS YP_002420521.1 218529705 7116875 complement(1779156..1782467) 1 NC_011757.1 KEGG: mex:Mext_1455 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 1782467 7116875 Mchl_1730 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002420521.1 1779156 R 440085 CDS YP_002420522.1 218529706 7116876 complement(1782590..1783492) 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: psp:PSPPH_1098 hypothetical protein; hypothetical protein 1783492 7116876 Mchl_1731 Methylobacterium extorquens CM4 hypothetical protein YP_002420522.1 1782590 R 440085 CDS YP_002420523.1 218529707 7114364 1783663..1784529 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B2299 transcription regulator, AraC family; AraC family transcriptional regulator 1784529 7114364 Mchl_1732 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420523.1 1783663 D 440085 CDS YP_002420524.1 218529708 7114528 complement(1784585..1786675) 1 NC_011757.1 PFAM: protein of unknown function DUF1355; KEGG: mex:Mext_1456 hypothetical protein; hypothetical protein 1786675 7114528 Mchl_1733 Methylobacterium extorquens CM4 hypothetical protein YP_002420524.1 1784585 R 440085 CDS YP_002420525.1 218529709 7114529 complement(1786866..1789703) 1 NC_011757.1 TIGRFAM: conserved hypothetical protein; KEGG: mex:Mext_1457 hypothetical protein; hypothetical protein 1789703 7114529 Mchl_1734 Methylobacterium extorquens CM4 hypothetical protein YP_002420525.1 1786866 R 440085 CDS YP_002420526.1 218529710 7114530 complement(1789717..1790631) 1 NC_011757.1 PFAM: protein of unknown function DUF58; KEGG: mex:Mext_1458 hypothetical protein; hypothetical protein 1790631 7114530 Mchl_1735 Methylobacterium extorquens CM4 hypothetical protein YP_002420526.1 1789717 R 440085 CDS YP_002420527.1 218529711 7114531 complement(1790643..1791653) 1 NC_011757.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase AAA; KEGG: mex:Mext_1459 ATPase; ATPase AAA 1791653 7114531 Mchl_1736 Methylobacterium extorquens CM4 ATPase AAA YP_002420527.1 1790643 R 440085 CDS YP_002420528.1 218529712 7114532 1791850..1792284 1 NC_011757.1 PFAM: thioesterase superfamily protein; KEGG: mex:Mext_1460 thioesterase superfamily protein; thioesterase 1792284 7114532 Mchl_1737 Methylobacterium extorquens CM4 thioesterase YP_002420528.1 1791850 D 440085 CDS YP_002420529.1 218529713 7114533 1792281..1792862 1 NC_011757.1 PFAM: protein of unknown function DUF1285; KEGG: mex:Mext_1461 hypothetical protein; hypothetical protein 1792862 7114533 Mchl_1738 Methylobacterium extorquens CM4 hypothetical protein YP_002420529.1 1792281 D 440085 CDS YP_002420530.1 218529714 7114534 1792859..1793542 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_1462 NUDIX hydrolase; NUDIX hydrolase 1793542 7114534 Mchl_1739 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002420530.1 1792859 D 440085 CDS YP_002420531.1 218529715 7114535 1793611..1793868 1 NC_011757.1 KEGG: mex:Mext_1463 hypothetical protein; hypothetical protein 1793868 7114535 Mchl_1740 Methylobacterium extorquens CM4 hypothetical protein YP_002420531.1 1793611 D 440085 CDS YP_002420532.1 218529716 7114536 1793865..1795151 1 NC_011757.1 PFAM: polynucleotide adenylyltransferase region; KEGG: mex:Mext_1464 polynucleotide adenylyltransferase region; polynucleotide adenylyltransferase region 1795151 7114536 Mchl_1741 Methylobacterium extorquens CM4 polynucleotide adenylyltransferase region YP_002420532.1 1793865 D 440085 CDS YP_002420533.1 218529717 7114537 complement(1795249..1795650) 1 NC_011757.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1795650 atpC 7114537 atpC Methylobacterium extorquens CM4 F0F1 ATP synthase subunit epsilon YP_002420533.1 1795249 R 440085 CDS YP_002420534.1 218529718 7114538 complement(1795677..1795928) 1 NC_011757.1 KEGG: mpo:Mpop_1464 hypothetical protein; hypothetical protein 1795928 7114538 Mchl_1743 Methylobacterium extorquens CM4 hypothetical protein YP_002420534.1 1795677 R 440085 CDS YP_002420535.1 218529719 7114539 complement(1795950..1797407) 1 NC_011757.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1797407 7114539 Mchl_1744 Methylobacterium extorquens CM4 F0F1 ATP synthase subunit beta YP_002420535.1 1795950 R 440085 CDS YP_002420536.1 218529720 7114540 complement(1797432..1798322) 1 NC_011757.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1798322 7114540 Mchl_1745 Methylobacterium extorquens CM4 F0F1 ATP synthase subunit gamma YP_002420536.1 1797432 R 440085 CDS YP_002420537.1 218529721 7114541 complement(1798490..1800019) 1 NC_011757.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1800019 7114541 Mchl_1746 Methylobacterium extorquens CM4 F0F1 ATP synthase subunit alpha YP_002420537.1 1798490 R 440085 CDS YP_002420538.1 218529722 7114542 complement(1800094..1800663) 1 NC_011757.1 TIGRFAM: ATP synthase F1 subunit delta; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: mpo:Mpop_1468 ATP synthase F1 subunit delta; ATP synthase F1 subunit delta 1800663 7114542 Mchl_1747 Methylobacterium extorquens CM4 ATP synthase F1 subunit delta YP_002420538.1 1800094 R 440085 CDS YP_002420539.1 218529723 7114543 complement(1800932..1802002) 1 NC_011757.1 PFAM: ferrochelatase; KEGG: mex:Mext_1470 ferrochelatase; ferrochelatase 1802002 7114543 Mchl_1748 Methylobacterium extorquens CM4 ferrochelatase YP_002420539.1 1800932 R 440085 CDS YP_002420540.1 218529724 7114544 1802194..1803165 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_1471 methyltransferase type 11; type 11 methyltransferase 1803165 7114544 Mchl_1749 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002420540.1 1802194 D 440085 CDS YP_002420541.1 218529725 7114545 1803173..1804675 1 NC_011757.1 PFAM: metallophosphoesterase; 5'-nucleotidase domain protein; KEGG: mex:Mext_1472 5'-nucleotidase; 5'-nucleotidase 1804675 7114545 Mchl_1750 Methylobacterium extorquens CM4 5'-nucleotidase YP_002420541.1 1803173 D 440085 CDS YP_002420542.1 218529726 7114546 1804843..1805547 1 NC_011757.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: mex:Mext_1473 uracil-DNA glycosylase superfamily protein; uracil-DNA glycosylase superfamily protein 1805547 7114546 Mchl_1751 Methylobacterium extorquens CM4 uracil-DNA glycosylase superfamily protein YP_002420542.1 1804843 D 440085 CDS YP_002420543.1 218529727 7114547 1805790..1806620 1 NC_011757.1 SMART: rhodanese; KEGG: mex:Mext_1474 rhodanese; rhodanese 1806620 7114547 Mchl_1752 Methylobacterium extorquens CM4 rhodanese YP_002420543.1 1805790 D 440085 CDS YP_002420544.1 218529728 7114548 1806623..1808026 1 NC_011757.1 TIGRFAM: chromate transporter chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: mex:Mext_1475 chromate transporter; chromate ion transporter (CHR) family chromate transporter 1808026 7114548 Mchl_1753 Methylobacterium extorquens CM4 chromate ion transporter (CHR) family chromate transporter YP_002420544.1 1806623 D 440085 CDS YP_002420545.1 218529729 7114549 complement(1808170..1808367) 1 NC_011757.1 KEGG: mex:Mext_1476 hypothetical protein; hypothetical protein 1808367 7114549 Mchl_1754 Methylobacterium extorquens CM4 hypothetical protein YP_002420545.1 1808170 R 440085 CDS YP_002420546.1 218529730 7114550 complement(1808501..1809403) 1 NC_011757.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: mex:Mext_1477 PpiC-type peptidyl-prolyl cis-trans isomerase; PpiC-type peptidyl-prolyl cis-trans isomerase 1809403 7114550 Mchl_1755 Methylobacterium extorquens CM4 PpiC-type peptidyl-prolyl cis-trans isomerase YP_002420546.1 1808501 R 440085 CDS YP_002420547.1 218529731 7114551 1809878..1812790 1 NC_011757.1 TIGRFAM: preprotein translocase, Secsubunit alpha; PFAM: SEC-C motif domain protein; SecA DEAD domain protein; SecA Wing and Scaffold; SecA preprotein cross-linking region; KEGG: mex:Mext_1478 preprotein translocase, Secsubunit alpha; preprotein translocase subunit SecA 1812790 7114551 Mchl_1756 Methylobacterium extorquens CM4 preprotein translocase subunit SecA YP_002420547.1 1809878 D 440085 CDS YP_002420548.1 218529732 7114552 1812798..1813208 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_1479 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 1813208 7114552 Mchl_1757 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002420548.1 1812798 D 440085 CDS YP_002420549.1 218529733 7114553 complement(1813213..1814376) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_1480 beta-lactamase; beta-lactamase 1814376 ampC 7114553 ampC Methylobacterium extorquens CM4 beta-lactamase YP_002420549.1 1813213 R 440085 CDS YP_002420550.1 218529734 7114554 1814500..1815414 1 NC_011757.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: mex:Mext_1481 4'-phosphopantetheinyl transferase; 4'-phosphopantetheinyl transferase 1815414 7114554 Mchl_1759 Methylobacterium extorquens CM4 4'-phosphopantetheinyl transferase YP_002420550.1 1814500 D 440085 CDS YP_002420551.1 218529735 7114555 1815411..1815866 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_1482 NUDIX hydrolase; NUDIX hydrolase 1815866 7114555 Mchl_1760 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002420551.1 1815411 D 440085 CDS YP_002420552.1 218529736 7114556 complement(1815901..1817169) 1 NC_011757.1 TIGRFAM: esterase, PHB depolymerase family; PFAM: esterase PHB depolymerase; KEGG: mex:Mext_1483 PHB depolymerase family esterase; esterase, PHB depolymerase family 1817169 7114556 Mchl_1761 Methylobacterium extorquens CM4 esterase, PHB depolymerase family YP_002420552.1 1815901 R 440085 CDS YP_002420553.1 218529737 7114557 complement(1817243..1817692) 1 NC_011757.1 KEGG: mex:Mext_1484 CopG family transcriptional regulator; CopG family transcriptional regulator 1817692 7114557 Mchl_1762 Methylobacterium extorquens CM4 CopG family transcriptional regulator YP_002420553.1 1817243 R 440085 CDS YP_002420554.1 218529738 7114558 complement(1817899..1818609) 1 NC_011757.1 KEGG: mex:Mext_1485 DNA polymerase III epsilon subunit; TIGRFAM: DNA polymerase III subunit epsilon; PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; DNA polymerase III subunit epsilon 1818609 7114558 Mchl_1763 Methylobacterium extorquens CM4 DNA polymerase III subunit epsilon YP_002420554.1 1817899 R 440085 CDS YP_002420555.1 218529739 7114559 1818732..1819016 1 NC_011757.1 PFAM: protein of unknown function DUF497; KEGG: mex:Mext_1486 hypothetical protein; hypothetical protein 1819016 7114559 Mchl_1764 Methylobacterium extorquens CM4 hypothetical protein YP_002420555.1 1818732 D 440085 CDS YP_002420556.1 218529740 7114560 1819000..1819335 1 NC_011757.1 SMART: helix-turn-helix domain protein; KEGG: mex:Mext_1487 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 1819335 7114560 Mchl_1765 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002420556.1 1819000 D 440085 CDS YP_002420557.1 218529741 7114561 complement(1819307..1819960) 1 NC_011757.1 KEGG: mex:Mext_1488 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; dephospho-CoA kinase 1819960 7114561 Mchl_1766 Methylobacterium extorquens CM4 dephospho-CoA kinase YP_002420557.1 1819307 R 440085 CDS YP_002420558.1 218529742 7114562 complement(1819957..1820823) 1 NC_011757.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: shikimate/quinate 5-dehydrogenase; shikimate dehydrogenase substrate binding domain protein; KEGG: mex:Mext_1489 shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 1820823 7114562 Mchl_1767 Methylobacterium extorquens CM4 shikimate 5-dehydrogenase YP_002420558.1 1819957 R 440085 CDS YP_002420559.1 218529743 7114563 complement(1820823..1821842) 1 NC_011757.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mex:Mext_1490 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 1821842 7114563 Mchl_1768 Methylobacterium extorquens CM4 cation diffusion facilitator family transporter YP_002420559.1 1820823 R 440085 CDS YP_002420560.1 218529744 7114564 complement(1821857..1822471) 1 NC_011757.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: mex:Mext_1491 maf protein; maf protein 1822471 7114564 Mchl_1769 Methylobacterium extorquens CM4 maf protein YP_002420560.1 1821857 R 440085 CDS YP_002420561.1 218529745 7114565 complement(1822488..1823624) 1 NC_011757.1 KEGG: mex:Mext_1492 capsular polysaccharide biosynthesis protein-like protein; capsular polysaccharide biosynthesis protein-like protein 1823624 7114565 Mchl_1770 Methylobacterium extorquens CM4 capsular polysaccharide biosynthesis protein-like protein YP_002420561.1 1822488 R 440085 CDS YP_002420562.1 218529746 7114566 complement(1823636..1824466) 1 NC_011757.1 PFAM: protein of unknown function DUF299; KEGG: mex:Mext_1493 hypothetical protein; hypothetical protein 1824466 7114566 Mchl_1771 Methylobacterium extorquens CM4 hypothetical protein YP_002420562.1 1823636 R 440085 CDS YP_002420563.1 218529747 7114567 1825214..1826296 1 NC_011757.1 KEGG: mex:Mext_1494 uroporphyrinogen decarboxylase; TIGRFAM: uroporphyrinogen decarboxylase; PFAM: uroporphyrinogen decarboxylase (URO-D); uroporphyrinogen decarboxylase 1826296 7114567 Mchl_1772 Methylobacterium extorquens CM4 uroporphyrinogen decarboxylase YP_002420563.1 1825214 D 440085 CDS YP_002420564.1 218529748 7114568 1826293..1826742 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mpo:Mpop_1495 NUDIX hydrolase; NUDIX hydrolase 1826742 7114568 Mchl_1773 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002420564.1 1826293 D 440085 CDS YP_002420565.1 218529749 7114569 1826735..1827175 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1495 hypothetical protein; hypothetical protein 1827175 7114569 Mchl_1774 Methylobacterium extorquens CM4 hypothetical protein YP_002420565.1 1826735 D 440085 CDS YP_002420566.1 218529750 7114570 1827261..1827602 1 NC_011757.1 KEGG: mex:Mext_1496 hypothetical protein; hypothetical protein 1827602 7114570 Mchl_1775 Methylobacterium extorquens CM4 hypothetical protein YP_002420566.1 1827261 D 440085 CDS YP_002420567.1 218529751 7114571 complement(1827751..1828728) 1 NC_011757.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1828728 hisG 7114571 hisG Methylobacterium extorquens CM4 ATP phosphoribosyltransferase YP_002420567.1 1827751 R 440085 CDS YP_002420568.1 218529752 7114572 complement(1828725..1829888) 1 NC_011757.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 1829888 hisZ 7114572 hisZ Methylobacterium extorquens CM4 ATP phosphoribosyltransferase regulatory subunit YP_002420568.1 1828725 R 440085 CDS YP_002420569.1 218529753 7114573 complement(1830034..1830921) 1 NC_011757.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_1499 HAD family hydrolase; HAD-superfamily hydrolase 1830921 7114573 Mchl_1778 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002420569.1 1830034 R 440085 CDS YP_002420570.1 218529754 7114574 complement(1831042..1831668) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1500 regulatory protein TetR; regulatory protein TetR 1831668 7114574 Mchl_1779 Methylobacterium extorquens CM4 regulatory protein TetR YP_002420570.1 1831042 R 440085 CDS YP_002420571.1 218529755 7114575 1831860..1835276 1 NC_011757.1 Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase 1835276 7114575 Mchl_1780 Methylobacterium extorquens CM4 acylglycerophosphoethanolamine acyltransferase YP_002420571.1 1831860 D 440085 CDS YP_002420572.1 218529756 7114576 1835421..1835822 1 NC_011757.1 PFAM: protein of unknown function DUF1044; KEGG: mex:Mext_1502 hypothetical protein; hypothetical protein 1835822 7114576 Mchl_1781 Methylobacterium extorquens CM4 hypothetical protein YP_002420572.1 1835421 D 440085 CDS YP_002420573.1 218529757 7114577 1835806..1836129 1 NC_011757.1 KEGG: mex:Mext_1503 DNA-binding protein; XRE family transcriptional regulator 1836129 7114577 Mchl_1782 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002420573.1 1835806 D 440085 CDS YP_002420574.1 218529758 7114578 1836276..1836962 1 NC_011757.1 PFAM: DSBA oxidoreductase; KEGG: mex:Mext_1504 DsbA oxidoreductase; DSBA oxidoreductase 1836962 7114578 Mchl_1783 Methylobacterium extorquens CM4 DSBA oxidoreductase YP_002420574.1 1836276 D 440085 CDS YP_002420575.1 218529759 7114579 complement(1836984..1837976) 1 NC_011757.1 PFAM: rubrerythrin; protein of unknown function DUF125 transmembrane; KEGG: mex:Mext_1505 rubrerythrin; rubrerythrin 1837976 7114579 Mchl_1784 Methylobacterium extorquens CM4 rubrerythrin YP_002420575.1 1836984 R 440085 CDS YP_002420576.1 218529760 7114580 complement(1838025..1839047) 1 NC_011757.1 KEGG: mex:Mext_1506 carbonic anhydrase; carbonic anhydrase 1839047 7114580 Mchl_1785 Methylobacterium extorquens CM4 carbonic anhydrase YP_002420576.1 1838025 R 440085 CDS YP_002420577.1 218529761 7114581 1839207..1839659 1 NC_011757.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: mex:Mext_1507 molybdopterin biosynthesis MoaE protein; molybdopterin biosynthesis MoaE protein 1839659 7114581 Mchl_1786 Methylobacterium extorquens CM4 molybdopterin biosynthesis MoaE protein YP_002420577.1 1839207 D 440085 CDS YP_002420578.1 218529762 7114582 1839751..1840929 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_1508 hypothetical protein; hypothetical protein 1840929 7114582 Mchl_1787 Methylobacterium extorquens CM4 hypothetical protein YP_002420578.1 1839751 D 440085 CDS YP_002420579.1 218529763 7114583 complement(1840980..1842632) 1 NC_011757.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1842632 7114583 Mchl_1788 Methylobacterium extorquens CM4 malate:quinone oxidoreductase YP_002420579.1 1840980 R 440085 CDS YP_002420580.1 218529764 7114584 complement(1842965..1844128) 1 NC_011757.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor type A; KEGG: mex:Mext_1510 von Willebrand factor A; von Willebrand factor A 1844128 7114584 Mchl_1789 Methylobacterium extorquens CM4 von Willebrand factor A YP_002420580.1 1842965 R 440085 CDS YP_002420581.1 218529765 7114585 complement(1844125..1846446) 1 NC_011757.1 KEGG: mpo:Mpop_1511 hypothetical protein; hypothetical protein 1846446 7114585 Mchl_1790 Methylobacterium extorquens CM4 hypothetical protein YP_002420581.1 1844125 R 440085 CDS YP_002420582.1 218529766 7114586 complement(1846455..1847555) 1 NC_011757.1 PFAM: ATPase associated with various cellular activities AAA_5; KEGG: mex:Mext_1512 ATPase; ATPase AAA 1847555 7114586 Mchl_1791 Methylobacterium extorquens CM4 ATPase AAA YP_002420582.1 1846455 R 440085 CDS YP_002420583.1 218529767 7114587 complement(1847552..1849135) 1 NC_011757.1 KEGG: mpo:Mpop_1513 hypothetical protein; hypothetical protein 1849135 7114587 Mchl_1792 Methylobacterium extorquens CM4 hypothetical protein YP_002420583.1 1847552 R 440085 CDS YP_002420584.1 218529768 7114588 complement(1849135..1850502) 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_1514 zinc finger SWIM domain-containing protein; hypothetical protein 1850502 7114588 Mchl_1793 Methylobacterium extorquens CM4 hypothetical protein YP_002420584.1 1849135 R 440085 CDS YP_002420585.1 218529769 7114589 complement(1850698..1852188) 1 NC_011757.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1852188 7114589 Mchl_1794 Methylobacterium extorquens CM4 glucose-6-phosphate 1-dehydrogenase YP_002420585.1 1850698 R 440085 CDS YP_002420586.1 218529770 7114590 1852334..1852582 1 NC_011757.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: mex:Mext_1516 addiction module antidote protein; CopG/Arc/MetJ family addiction module antidote protein 1852582 7114590 Mchl_1795 Methylobacterium extorquens CM4 CopG/Arc/MetJ family addiction module antidote protein YP_002420586.1 1852334 D 440085 CDS YP_002420587.1 218529771 7114591 1852579..1852869 1 NC_011757.1 PFAM: plasmid stabilization system; KEGG: mex:Mext_1517 plasmid stabilization system protein; plasmid stabilization system 1852869 7114591 Mchl_1796 Methylobacterium extorquens CM4 plasmid stabilization system YP_002420587.1 1852579 D 440085 CDS YP_002420588.1 218529772 7114592 1852927..1853589 1 NC_011757.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: mex:Mext_1518 uracil-DNA glycosylase superfamily protein; uracil-DNA glycosylase superfamily protein 1853589 7114592 Mchl_1797 Methylobacterium extorquens CM4 uracil-DNA glycosylase superfamily protein YP_002420588.1 1852927 D 440085 CDS YP_002420589.1 218529773 7114593 complement(1853597..1855123) 1 NC_011757.1 KEGG: mex:Mext_1519 hypothetical protein; hypothetical protein 1855123 7114593 Mchl_1798 Methylobacterium extorquens CM4 hypothetical protein YP_002420589.1 1853597 R 440085 CDS YP_002420590.1 218529774 7114594 1855448..1856146 1 NC_011757.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1856146 7114594 Mchl_1799 Methylobacterium extorquens CM4 orotidine 5'-phosphate decarboxylase YP_002420590.1 1855448 D 440085 CDS YP_002420591.1 218529775 7114595 1856149..1856493 1 NC_011757.1 PFAM: protein of unknown function DUF1330; KEGG: mex:Mext_1521 hypothetical protein; hypothetical protein 1856493 7114595 Mchl_1800 Methylobacterium extorquens CM4 hypothetical protein YP_002420591.1 1856149 D 440085 CDS YP_002420592.1 218529776 7114596 complement(1856513..1857136) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1522 regulatory protein TetR; TetR family transcriptional regulator 1857136 7114596 Mchl_1801 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420592.1 1856513 R 440085 CDS YP_002420593.1 218529777 7114597 complement(1857359..1857559) 1 NC_011757.1 KEGG: mex:Mext_1523 hypothetical protein; hypothetical protein 1857559 7114597 Mchl_1802 Methylobacterium extorquens CM4 hypothetical protein YP_002420593.1 1857359 R 440085 CDS YP_002420594.1 218529778 7114598 complement(1857762..1858268) 1 NC_011757.1 TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; KEGG: mex:Mext_1524 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut 1858268 7114598 Mchl_1803 Methylobacterium extorquens CM4 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut YP_002420594.1 1857762 R 440085 CDS YP_002420595.1 218529779 7114599 1858365..1859147 1 NC_011757.1 KEGG: mex:Mext_1525 NUDIX hydrolase; NUDIX hydrolase 1859147 7114599 Mchl_1804 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002420595.1 1858365 D 440085 CDS YP_002420596.1 218529780 7114600 1859153..1859677 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_1525 NUDIX hydrolase; NUDIX hydrolase 1859677 7114600 Mchl_1805 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002420596.1 1859153 D 440085 CDS YP_002420597.1 218529781 7114601 1859904..1860590 1 NC_011757.1 PFAM: carbonic anhydrase; KEGG: mex:Mext_1526 carbonate dehydratase; carbonate dehydratase 1860590 7114601 Mchl_1806 Methylobacterium extorquens CM4 carbonate dehydratase YP_002420597.1 1859904 D 440085 CDS YP_002420598.1 218529782 7114602 complement(1860808..1861731) 1 NC_011757.1 PFAM: inositol monophosphatase; KEGG: mex:Mext_1527 inositol monophosphatase; inositol monophosphatase 1861731 7114602 Mchl_1807 Methylobacterium extorquens CM4 inositol monophosphatase YP_002420598.1 1860808 R 440085 CDS YP_002420599.1 218529783 7114603 1862086..1862826 1 NC_011757.1 KEGG: mex:Mext_1528 hypothetical protein; hypothetical protein 1862826 7114603 Mchl_1808 Methylobacterium extorquens CM4 hypothetical protein YP_002420599.1 1862086 D 440085 CDS YP_002420600.1 218529784 7114604 1863004..1865754 1 NC_011757.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: mex:Mext_1529 ATPase domain-containing protein; CheA signal transduction histidine kinase 1865754 7114604 Mchl_1809 Methylobacterium extorquens CM4 CheA signal transduction histidine kinase YP_002420600.1 1863004 D 440085 CDS YP_002420601.1 218529785 7114605 1865787..1866266 1 NC_011757.1 PFAM: CheW domain protein; KEGG: mex:Mext_1530 CheW domain-containing protein; CheW protein 1866266 7114605 Mchl_1810 Methylobacterium extorquens CM4 CheW protein YP_002420601.1 1865787 D 440085 CDS YP_002420602.1 218529786 7114606 1866287..1866709 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_1531 response regulator receiver; response regulator receiver protein 1866709 7114606 Mchl_1811 Methylobacterium extorquens CM4 response regulator receiver protein YP_002420602.1 1866287 D 440085 CDS YP_002420603.1 218529787 7114607 1866776..1867924 1 NC_011757.1 PFAM: CheB methylesterase; response regulator receiver; KEGG: mex:Mext_1532 protein-glutamate methylesterase; response regulator receiver modulated CheB methylesterase 1867924 7114607 Mchl_1812 Methylobacterium extorquens CM4 response regulator receiver modulated CheB methylesterase YP_002420603.1 1866776 D 440085 CDS YP_002420604.1 218529788 7114608 1867924..1868781 1 NC_011757.1 PFAM: MCP methyltransferase CheR-type; KEGG: mex:Mext_1533 protein-glutamate O-methyltransferase; CheR-typeMCP methyltransferase 1868781 7114608 Mchl_1813 Methylobacterium extorquens CM4 CheR-typeMCP methyltransferase YP_002420604.1 1867924 D 440085 CDS YP_002420605.1 218529789 7113542 1868828..1869553 1 NC_011757.1 PFAM: allophanate hydrolase subunit 1; KEGG: mex:Mext_1534 allophanate hydrolase subunit 1; allophanate hydrolase subunit 1 1869553 7113542 Mchl_1814 Methylobacterium extorquens CM4 allophanate hydrolase subunit 1 YP_002420605.1 1868828 D 440085 CDS YP_002420606.1 218529790 7113543 1869550..1870569 1 NC_011757.1 KEGG: mex:Mext_1535 UreA amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; urea amidolyase-like protein 1870569 7113543 Mchl_1815 Methylobacterium extorquens CM4 urea amidolyase-like protein YP_002420606.1 1869550 D 440085 CDS YP_002420607.1 218529791 7113544 1870616..1871710 1 NC_011757.1 KEGG: mex:Mext_1536 UV damage repair endonuclease; UV damage repair endonuclease 1871710 7113544 Mchl_1816 Methylobacterium extorquens CM4 UV damage repair endonuclease YP_002420607.1 1870616 D 440085 CDS YP_002420608.1 218529792 7113545 1871831..1874563 1 NC_011757.1 KEGG: mex:Mext_1537 hypothetical protein; hypothetical protein 1874563 7113545 Mchl_1817 Methylobacterium extorquens CM4 hypothetical protein YP_002420608.1 1871831 D 440085 CDS YP_002420609.1 218529793 7113546 1874633..1874818 1 NC_011757.1 PFAM: Hypoxia induced protein conserved region; KEGG: mex:Mext_1538 hypoxia induced protein region; Hypoxia induced protein conserved region 1874818 7113546 Mchl_1818 Methylobacterium extorquens CM4 Hypoxia induced protein conserved region YP_002420609.1 1874633 D 440085 CDS YP_002420610.1 218529794 7113547 complement(1874851..1875354) 1 NC_011757.1 KEGG: mex:Mext_1539 hypothetical protein; hypothetical protein 1875354 7113547 Mchl_1819 Methylobacterium extorquens CM4 hypothetical protein YP_002420610.1 1874851 R 440085 CDS YP_002420611.1 218529795 7113548 1875606..1876244 1 NC_011757.1 KEGG: mex:Mext_1540 hypothetical protein; hypothetical protein 1876244 7113548 Mchl_1820 Methylobacterium extorquens CM4 hypothetical protein YP_002420611.1 1875606 D 440085 CDS YP_002420612.1 218529796 7113549 1876365..1876937 1 NC_011757.1 TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: mex:Mext_1541 ATP--cobalamin adenosyltransferase; ATP/cobalamin adenosyltransferase 1876937 7113549 Mchl_1821 Methylobacterium extorquens CM4 ATP/cobalamin adenosyltransferase YP_002420612.1 1876365 D 440085 CDS YP_002420613.1 218529797 7113550 1877100..1877849 1 NC_011757.1 PFAM: electron transfer flavoprotein alpha/beta-subunit; KEGG: mex:Mext_1542 electron transfer flavoprotein alpha/beta-subunit; electron transfer flavoprotein alpha/beta-subunit 1877849 7113550 Mchl_1822 Methylobacterium extorquens CM4 electron transfer flavoprotein alpha/beta-subunit YP_002420613.1 1877100 D 440085 CDS YP_002420614.1 218529798 7113551 1877930..1878883 1 NC_011757.1 PFAM: electron transfer flavoprotein alpha/beta-subunit ; electron transfer flavoprotein subunit alpha; KEGG: mex:Mext_1543 electron transfer flavoprotein subunit alpha; electron transfer flavoprotein subunit alpha 1878883 7113551 Mchl_1823 Methylobacterium extorquens CM4 electron transfer flavoprotein subunit alpha YP_002420614.1 1877930 D 440085 CDS YP_002420615.1 218529799 7113552 1879042..1879923 1 NC_011757.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: mex:Mext_1544 3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase 1879923 7113552 Mchl_1824 Methylobacterium extorquens CM4 3-hydroxybutyryl-CoA dehydrogenase YP_002420615.1 1879042 D 440085 CDS YP_002420616.1 218529800 7113553 complement(1880005..1880283) 1 NC_011757.1 KEGG: mex:Mext_1545 hypothetical protein; hypothetical protein 1880283 7113553 Mchl_1825 Methylobacterium extorquens CM4 hypothetical protein YP_002420616.1 1880005 R 440085 CDS YP_002420617.1 218529801 7113554 complement(1880475..1881485) 1 NC_011757.1 TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_1546 PIG3 family NAD(P)H quinone oxidoreductase; NAD(P)H quinone oxidoreductase, PIG3 family 1881485 7113554 Mchl_1826 Methylobacterium extorquens CM4 NAD(P)H quinone oxidoreductase, PIG3 family YP_002420617.1 1880475 R 440085 CDS YP_002420618.1 218529802 7113555 complement(1881630..1882280) 1 NC_011757.1 KEGG: mex:Mext_1547 uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; uracil phosphoribosyltransferase 1882280 7113555 Mchl_1827 Methylobacterium extorquens CM4 uracil phosphoribosyltransferase YP_002420618.1 1881630 R 440085 CDS YP_002420619.1 218529803 7113556 complement(1882377..1884470) 1 NC_011757.1 KEGG: mex:Mext_1549 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX 1884470 7113556 Mchl_1828 Methylobacterium extorquens CM4 glycogen debranching protein GlgX YP_002420619.1 1882377 R 440085 CDS YP_002420620.1 218529804 7113557 complement(1884553..1885977) 1 NC_011757.1 PFAM: glycosyl transferase family 20; KEGG: mex:Mext_1550 alpha,alpha-trehalose-phosphate synthase (UDP-forming); alpha,alpha-trehalose-phosphate synthase 1885977 7113557 Mchl_1829 Methylobacterium extorquens CM4 alpha,alpha-trehalose-phosphate synthase YP_002420620.1 1884553 R 440085 CDS YP_002420621.1 218529805 7113558 1886508..1886987 1 NC_011757.1 KEGG: mex:Mext_1551 hypothetical protein; hypothetical protein 1886987 7113558 Mchl_1830 Methylobacterium extorquens CM4 hypothetical protein YP_002420621.1 1886508 D 440085 CDS YP_002420622.1 218529806 7113559 1886999..1887406 1 NC_011757.1 PFAM: protein of unknown function DUF1469; KEGG: mex:Mext_1552 hypothetical protein; hypothetical protein 1887406 7113559 Mchl_1831 Methylobacterium extorquens CM4 hypothetical protein YP_002420622.1 1886999 D 440085 CDS YP_002420623.1 218529807 7113560 1887403..1887789 1 NC_011757.1 KEGG: mex:Mext_1553 hypothetical protein; hypothetical protein 1887789 7113560 Mchl_1832 Methylobacterium extorquens CM4 hypothetical protein YP_002420623.1 1887403 D 440085 CDS YP_002420624.1 218529808 7113561 1887854..1888690 1 NC_011757.1 KEGG: mex:Mext_1554 hypothetical protein; hypothetical protein 1888690 7113561 Mchl_1833 Methylobacterium extorquens CM4 hypothetical protein YP_002420624.1 1887854 D 440085 CDS YP_002420625.1 218529809 7113562 complement(1888770..1890281) 1 NC_011757.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1890281 hisS 7113562 hisS Methylobacterium extorquens CM4 histidyl-tRNA synthetase YP_002420625.1 1888770 R 440085 CDS YP_002420626.1 218529810 7113563 complement(1890365..1890736) 1 NC_011757.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: mex:Mext_1556 export-related chaperone CsaA; export-related chaperone CsaA 1890736 7113563 Mchl_1835 Methylobacterium extorquens CM4 export-related chaperone CsaA YP_002420626.1 1890365 R 440085 CDS YP_002420627.1 218529811 7113564 complement(1890832..1891350) 1 NC_011757.1 KEGG: mex:Mext_1557 hypothetical protein; hypothetical protein 1891350 7113564 Mchl_1836 Methylobacterium extorquens CM4 hypothetical protein YP_002420627.1 1890832 R 440085 CDS YP_002420628.1 218529812 7113565 complement(1891417..1892670) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1558 major facilitator transporter; major facilitator superfamily protein 1892670 7113565 Mchl_1837 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002420628.1 1891417 R 440085 CDS YP_002420629.1 218529813 7113566 complement(1892961..1893467) 1 NC_011757.1 TIGRFAM: protein-export protein SecB; PFAM: protein export chaperone SecB; KEGG: mex:Mext_1559 protein-export protein SecB; protein-export protein SecB 1893467 7113566 Mchl_1838 Methylobacterium extorquens CM4 protein-export protein SecB YP_002420629.1 1892961 R 440085 CDS YP_002420630.1 218529814 7113567 1893929..1894648 1 NC_011757.1 PFAM: import inner membrane translocase subunit Tim44; KEGG: mex:Mext_1560 import inner membrane translocase subunit Tim44; import inner membrane translocase subunit Tim44 1894648 7113567 Mchl_1839 Methylobacterium extorquens CM4 import inner membrane translocase subunit Tim44 YP_002420630.1 1893929 D 440085 CDS YP_002420631.1 218529815 7113568 1894661..1895917 1 NC_011757.1 PFAM: MltA domain protein; 3D domain protein; KEGG: mex:Mext_1561 MltA domain-containing protein; MltA domain-containing protein 1895917 7113568 Mchl_1840 Methylobacterium extorquens CM4 MltA domain-containing protein YP_002420631.1 1894661 D 440085 CDS YP_002420632.1 218529816 7113569 1895914..1896699 1 NC_011757.1 PFAM: Smr protein/MutS2; KEGG: mex:Mext_1562 Smr protein/MutS2; Smr protein/MutS2 1896699 7113569 Mchl_1841 Methylobacterium extorquens CM4 Smr protein/MutS2 YP_002420632.1 1895914 D 440085 CDS YP_002420633.1 218529817 7113570 1896952..1898295 1 NC_011757.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1898295 rho 7113570 rho Methylobacterium extorquens CM4 transcription termination factor Rho YP_002420633.1 1896952 D 440085 CDS YP_002420634.1 218529818 7113571 1898569..1900302 1 NC_011757.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1900302 7113571 Mchl_1843 Methylobacterium extorquens CM4 pyruvate dehydrogenase YP_002420634.1 1898569 D 440085 CDS YP_002420635.1 218529819 7113572 complement(1900415..1901335) 1 NC_011757.1 KEGG: mex:Mext_1565 hypothetical protein; hypothetical protein 1901335 7113572 Mchl_1844 Methylobacterium extorquens CM4 hypothetical protein YP_002420635.1 1900415 R 440085 CDS YP_002420636.1 218529820 7113573 complement(1901641..1902387) 1 NC_011757.1 PFAM: integral membrane protein TerC; KEGG: mex:Mext_1566 integral membrane protein TerC; integral membrane protein TerC 1902387 7113573 Mchl_1845 Methylobacterium extorquens CM4 integral membrane protein TerC YP_002420636.1 1901641 R 440085 CDS YP_002420637.1 218529821 7113574 complement(1902404..1903333) 1 NC_011757.1 similar to YegS from E. coli; lipid kinase 1903333 7113574 Mchl_1846 Methylobacterium extorquens CM4 lipid kinase YP_002420637.1 1902404 R 440085 CDS YP_002420638.1 218529822 7113575 1903911..1904726 1 NC_011757.1 KEGG: mex:Mext_1568 hypothetical protein; hypothetical protein 1904726 7113575 Mchl_1847 Methylobacterium extorquens CM4 hypothetical protein YP_002420638.1 1903911 D 440085 CDS YP_002420639.1 218529823 7113576 1905037..1906347 1 NC_011757.1 KEGG: mex:Mext_1569 hypothetical protein; hypothetical protein 1906347 7113576 Mchl_1848 Methylobacterium extorquens CM4 hypothetical protein YP_002420639.1 1905037 D 440085 CDS YP_002420640.1 218529824 7113577 complement(1906378..1907256) 1 NC_011757.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: mex:Mext_1570 acid phosphatase; acid phosphatase 1907256 7113577 Mchl_1849 Methylobacterium extorquens CM4 acid phosphatase YP_002420640.1 1906378 R 440085 CDS YP_002420641.1 218529825 7113578 complement(1907423..1908301) 1 NC_011757.1 KEGG: mpo:Mpop_1668 hypothetical protein; hypothetical protein 1908301 7113578 Mchl_1850 Methylobacterium extorquens CM4 hypothetical protein YP_002420641.1 1907423 R 440085 CDS YP_002420642.1 218529826 7113579 complement(1908310..1908606) 1 NC_011757.1 KEGG: mex:Mext_1572 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 1908606 7113579 Mchl_1851 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002420642.1 1908310 R 440085 CDS YP_002420643.1 218529827 7113580 complement(1908637..1909017) 1 NC_011757.1 KEGG: mex:Mext_1573 RelE-like cytotoxic translational repressor of toxin-antitoxin stability system; RelE-like cytotoxic translational repressor of toxin-antitoxin stability system 1909017 7113580 Mchl_1852 Methylobacterium extorquens CM4 RelE-like cytotoxic translational repressor of toxin-antitoxin stability system YP_002420643.1 1908637 R 440085 CDS YP_002420644.1 218529828 7113581 complement(1909074..1909916) 1 NC_011757.1 KEGG: mex:Mext_1574 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 1909916 7113581 Mchl_1853 Methylobacterium extorquens CM4 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_002420644.1 1909074 R 440085 CDS YP_002420645.1 218529829 7113582 complement(1910079..1910546) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_1575 cyclic nucleotide-binding; cyclic nucleotide-binding protein 1910546 7113582 Mchl_1854 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002420645.1 1910079 R 440085 CDS YP_002420646.1 218529830 7113583 complement(1910733..1911419) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_1576 response regulator receiver; transcriptional regulator 1911419 7113583 Mchl_1855 Methylobacterium extorquens CM4 transcriptional regulator YP_002420646.1 1910733 R 440085 CDS YP_002420647.1 218529831 7113584 1911710..1912303 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_1577 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 1912303 7113584 Mchl_1856 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002420647.1 1911710 D 440085 CDS YP_002420648.1 218529832 7113585 complement(1912343..1913086) 1 NC_011757.1 PFAM: alanine racemase domain protein; KEGG: mex:Mext_1578 alanine racemase domain-containing protein; alanine racemase domain-containing protein 1913086 7113585 Mchl_1857 Methylobacterium extorquens CM4 alanine racemase domain-containing protein YP_002420648.1 1912343 R 440085 CDS YP_002420649.1 218529833 7113586 1913395..1916022 1 NC_011757.1 TIGRFAM: leucyl-tRNA synthetase; KEGG: mex:Mext_1579 leucyl-tRNA synthetase; leucyl-tRNA synthetase 1916022 7113586 Mchl_1858 Methylobacterium extorquens CM4 leucyl-tRNA synthetase YP_002420649.1 1913395 D 440085 CDS YP_002420650.1 218529834 7113587 1916113..1917447 1 NC_011757.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1917447 trmE 7113587 trmE Methylobacterium extorquens CM4 tRNA modification GTPase TrmE YP_002420650.1 1916113 D 440085 CDS YP_002420651.1 218529835 7113588 complement(1917461..1918483) 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; KEGG: mex:Mext_1581 PAS sensor protein; PAS sensor protein 1918483 7113588 Mchl_1860 Methylobacterium extorquens CM4 PAS sensor protein YP_002420651.1 1917461 R 440085 CDS YP_002420652.1 218529836 7113589 1918836..1919117 1 NC_011757.1 KEGG: mex:Mext_1582 hypothetical protein; hypothetical protein 1919117 7113589 Mchl_1861 Methylobacterium extorquens CM4 hypothetical protein YP_002420652.1 1918836 D 440085 CDS YP_002420653.1 218529837 7113590 1919291..1921165 1 NC_011757.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1921165 7113590 Mchl_1862 Methylobacterium extorquens CM4 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002420653.1 1919291 D 440085 CDS YP_002420654.1 218529838 7113591 1921200..1921835 1 NC_011757.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: mex:Mext_1584 methyltransferase GidB; methyltransferase GidB 1921835 7113591 Mchl_1863 Methylobacterium extorquens CM4 methyltransferase GidB YP_002420654.1 1921200 D 440085 CDS YP_002420655.1 218529839 7113592 1921832..1922692 1 NC_011757.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: mex:Mext_1585 cobyrinic acid ac-diamide synthase; cobyrinic acid ac-diamide synthase 1922692 7113592 Mchl_1864 Methylobacterium extorquens CM4 cobyrinic acid ac-diamide synthase YP_002420655.1 1921832 D 440085 CDS YP_002420656.1 218529840 7113593 1922726..1923622 1 NC_011757.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: mex:Mext_1586 ParB-like partition protein; parB-like partition protein 1923622 7113593 Mchl_1865 Methylobacterium extorquens CM4 parB-like partition protein YP_002420656.1 1922726 D 440085 CDS YP_002420657.1 218529841 7113594 complement(1923764..1924795) 1 NC_011757.1 required for the assembly and function of the DNAX complex which are required for the assembly of the subunit beta onto primed DNA; DNA polymerase III subunit delta 1924795 holA 7113594 holA Methylobacterium extorquens CM4 DNA polymerase III subunit delta YP_002420657.1 1923764 R 440085 CDS YP_002420658.1 218529842 7113595 complement(1924806..1925372) 1 NC_011757.1 KEGG: mex:Mext_1588 hypothetical protein; hypothetical protein 1925372 7113595 Mchl_1867 Methylobacterium extorquens CM4 hypothetical protein YP_002420658.1 1924806 R 440085 CDS YP_002420659.1 218529843 7113596 1925758..1926102 1 NC_011757.1 KEGG: mex:Mext_1589 hypothetical protein; hypothetical protein 1926102 7113596 Mchl_1868 Methylobacterium extorquens CM4 hypothetical protein YP_002420659.1 1925758 D 440085 CDS YP_002420660.1 218529844 7113597 1926237..1927340 1 NC_011757.1 KEGG: mex:Mext_1590 hypothetical protein; hypothetical protein 1927340 7113597 Mchl_1869 Methylobacterium extorquens CM4 hypothetical protein YP_002420660.1 1926237 D 440085 CDS YP_002420661.1 218529845 7113598 1927393..1927689 1 NC_011757.1 KEGG: lch:Lcho_2218 hypothetical protein; hypothetical protein 1927689 7113598 Mchl_1870 Methylobacterium extorquens CM4 hypothetical protein YP_002420661.1 1927393 D 440085 CDS YP_002420662.1 218529846 7113599 1927676..1928035 1 NC_011757.1 KEGG: rle:pRL70167 hypothetical protein; hypothetical protein 1928035 7113599 Mchl_1871 Methylobacterium extorquens CM4 hypothetical protein YP_002420662.1 1927676 D 440085 CDS YP_002420663.1 218529847 7113600 complement(1928072..1929016) 1 NC_011757.1 KEGG: mex:Mext_1591 hypothetical protein; hypothetical protein 1929016 7113600 Mchl_1872 Methylobacterium extorquens CM4 hypothetical protein YP_002420663.1 1928072 R 440085 CDS YP_002420664.1 218529848 7113601 complement(1929034..1929972) 1 NC_011757.1 PFAM: prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase; prephenate dehydrogenase 1929972 7113601 Mchl_1873 Methylobacterium extorquens CM4 prephenate dehydrogenase YP_002420664.1 1929034 R 440085 CDS YP_002420665.1 218529849 7113602 complement(1929969..1931087) 1 NC_011757.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1931087 7113602 Mchl_1874 Methylobacterium extorquens CM4 histidinol-phosphate aminotransferase YP_002420665.1 1929969 R 440085 CDS YP_002420666.1 218529850 7113603 complement(1931201..1931698) 1 NC_011757.1 KEGG: mex:Mext_1594 hypothetical protein; hypothetical protein 1931698 7113603 Mchl_1875 Methylobacterium extorquens CM4 hypothetical protein YP_002420666.1 1931201 R 440085 CDS YP_002420667.1 218529851 7113604 complement(1931845..1934079) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_1595 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 1934079 7113604 Mchl_1876 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002420667.1 1931845 R 440085 CDS YP_002420668.1 218529852 7113605 complement(1934351..1936357) 1 NC_011757.1 PFAM: K potassium transporter; KEGG: mex:Mext_1596 K potassium transporter; K potassium transporter 1936357 7113605 Mchl_1877 Methylobacterium extorquens CM4 K potassium transporter YP_002420668.1 1934351 R 440085 CDS YP_002420669.1 218529853 7113606 complement(1936676..1938004) 1 NC_011757.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1938004 ispG 7113606 ispG Methylobacterium extorquens CM4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002420669.1 1936676 R 440085 CDS YP_002420670.1 218529854 7113607 1938336..1939580 1 NC_011757.1 PFAM: patatin; KEGG: mex:Mext_1598 patatin; patatin 1939580 7113607 Mchl_1879 Methylobacterium extorquens CM4 patatin YP_002420670.1 1938336 D 440085 CDS YP_002420671.1 218529855 7113608 1939672..1940736 1 NC_011757.1 PFAM: regulatory protein ArsR; UbiE/COQ5 methyltransferase; methyltransferase small; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_1599 methyltransferase type 11; ArsR family transcriptional regulator 1940736 7113608 Mchl_1880 Methylobacterium extorquens CM4 ArsR family transcriptional regulator YP_002420671.1 1939672 D 440085 CDS YP_002420672.1 218529856 7113609 1940836..1941768 1 NC_011757.1 KEGG: mex:Mext_1600 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 1941768 7113609 Mchl_1881 Methylobacterium extorquens CM4 5,10-methylenetetrahydrofolate reductase YP_002420672.1 1940836 D 440085 CDS YP_002420673.1 218529857 7113610 1941968..1945720 1 NC_011757.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 1945720 metH 7113610 metH Methylobacterium extorquens CM4 B12-dependent methionine synthase YP_002420673.1 1941968 D 440085 CDS YP_002420674.1 218529858 7113611 1945864..1946079 1 NC_011757.1 KEGG: mex:Mext_1602 hypothetical protein; hypothetical protein 1946079 7113611 Mchl_1883 Methylobacterium extorquens CM4 hypothetical protein YP_002420674.1 1945864 D 440085 CDS YP_002420675.1 218529859 7113612 complement(1946173..1947375) 1 NC_011757.1 KEGG: mex:Mext_1603 acyl-CoA N-acyltransferase related protein; acyl-CoA N-acyltransferase-like protein 1947375 7113612 Mchl_1884 Methylobacterium extorquens CM4 acyl-CoA N-acyltransferase-like protein YP_002420675.1 1946173 R 440085 CDS YP_002420676.1 218529860 7113613 1947582..1948634 1 NC_011757.1 PFAM: polysaccharide deacetylase; KEGG: mex:Mext_1604 polysaccharide deacetylase; polysaccharide deacetylase 1948634 7113613 Mchl_1885 Methylobacterium extorquens CM4 polysaccharide deacetylase YP_002420676.1 1947582 D 440085 CDS YP_002420677.1 218529861 7113614 complement(1948647..1949084) 1 NC_011757.1 KEGG: mex:Mext_1605 hypothetical protein; hypothetical protein 1949084 7113614 Mchl_1886 Methylobacterium extorquens CM4 hypothetical protein YP_002420677.1 1948647 R 440085 CDS YP_002420678.1 218529862 7113615 complement(1949220..1949426) 1 NC_011757.1 KEGG: mex:Mext_1606 hypothetical protein; hypothetical protein 1949426 7113615 Mchl_1887 Methylobacterium extorquens CM4 hypothetical protein YP_002420678.1 1949220 R 440085 CDS YP_002420679.1 218529863 7113616 1949756..1950904 1 NC_011757.1 PFAM: cytochrome oxidase assembly; KEGG: mex:Mext_1607 cytochrome oxidase assembly; cytochrome oxidase assembly 1950904 7113616 Mchl_1888 Methylobacterium extorquens CM4 cytochrome oxidase assembly YP_002420679.1 1949756 D 440085 CDS YP_002420680.1 218529864 7113617 1951205..1951885 1 NC_011757.1 PFAM: Hly-III family protein; KEGG: mex:Mext_1608 Hly-III family protein; Hly-III family protein 1951885 7113617 Mchl_1889 Methylobacterium extorquens CM4 Hly-III family protein YP_002420680.1 1951205 D 440085 CDS YP_002420681.1 218529865 7113618 complement(1952007..1952270) 1 NC_011757.1 KEGG: mpo:Mpop_1630 hypothetical protein; hypothetical protein 1952270 7113618 Mchl_1890 Methylobacterium extorquens CM4 hypothetical protein YP_002420681.1 1952007 R 440085 CDS YP_002420682.1 218529866 7113619 1952708..1954600 1 NC_011757.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 1954600 7113619 Mchl_1891 Methylobacterium extorquens CM4 thiamine biosynthesis protein ThiC YP_002420682.1 1952708 D 440085 CDS YP_002420683.1 218529867 7113620 1954817..1955164 1 NC_011757.1 KEGG: mex:Mext_1611 hypothetical protein; hypothetical protein 1955164 7113620 Mchl_1892 Methylobacterium extorquens CM4 hypothetical protein YP_002420683.1 1954817 D 440085 CDS YP_002420684.1 218529868 7113621 complement(1955341..1955715) 1 NC_011757.1 PFAM: flagellar FlaF family protein; KEGG: mex:Mext_1612 flagellar FlaF family protein; flagellar FlaF family protein 1955715 7113621 Mchl_1893 Methylobacterium extorquens CM4 flagellar FlaF family protein YP_002420684.1 1955341 R 440085 CDS YP_002420685.1 218529869 7113622 1955863..1956132 1 NC_011757.1 KEGG: mex:Mext_1613 hypothetical protein; hypothetical protein 1956132 7113622 Mchl_1894 Methylobacterium extorquens CM4 hypothetical protein YP_002420685.1 1955863 D 440085 CDS YP_002420686.1 218529870 7113623 complement(1956257..1956397) 1 NC_011757.1 KEGG: mpo:Mpop_1623 hypothetical protein; hypothetical protein 1956397 7113623 Mchl_1895 Methylobacterium extorquens CM4 hypothetical protein YP_002420686.1 1956257 R 440085 CDS YP_002420687.1 218529871 7116549 complement(1956582..1956908) 1 NC_011757.1 KEGG: mex:Mext_1614 hypothetical protein; hypothetical protein 1956908 7116549 Mchl_1896 Methylobacterium extorquens CM4 hypothetical protein YP_002420687.1 1956582 R 440085 CDS YP_002420688.1 218529872 7116712 complement(1957144..1957713) 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_1615 metallophosphoesterase; metallophosphoesterase 1957713 7116712 Mchl_1897 Methylobacterium extorquens CM4 metallophosphoesterase YP_002420688.1 1957144 R 440085 CDS YP_002420689.1 218529873 7116713 complement(1957771..1958871) 1 NC_011757.1 TIGRFAM: TonB family protein; KEGG: mex:Mext_1616 TonB family protein; TonB family protein 1958871 7116713 Mchl_1898 Methylobacterium extorquens CM4 TonB family protein YP_002420689.1 1957771 R 440085 CDS YP_002420690.1 218529874 7116714 complement(1958912..1959373) 1 NC_011757.1 TIGRFAM: protein TolR; PFAM: biopolymertransporter ExbD/TolR; KEGG: mex:Mext_1617 protein TolR; protein TolR 1959373 7116714 Mchl_1899 Methylobacterium extorquens CM4 protein TolR YP_002420690.1 1958912 R 440085 CDS YP_002420691.1 218529875 7116715 complement(1959458..1960159) 1 NC_011757.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: mex:Mext_1618 MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel 1960159 7116715 Mchl_1900 Methylobacterium extorquens CM4 MotA/TolQ/ExbB proton channel YP_002420691.1 1959458 R 440085 CDS YP_002420692.1 218529876 7116716 complement(1960231..1960713) 1 NC_011757.1 KEGG: mex:Mext_1619 hypothetical protein; hypothetical protein 1960713 7116716 Mchl_1901 Methylobacterium extorquens CM4 hypothetical protein YP_002420692.1 1960231 R 440085 CDS YP_002420693.1 218529877 7116717 1961282..1961713 1 NC_011757.1 PFAM: heat shock protein Hsp20; KEGG: mex:Mext_1620 heat shock protein HSP20; heat shock protein Hsp20 1961713 7116717 Mchl_1902 Methylobacterium extorquens CM4 heat shock protein Hsp20 YP_002420693.1 1961282 D 440085 CDS YP_002420694.1 218529878 7116718 1961887..1962168 1 NC_011757.1 PFAM: protein of unknown function DUF1150; KEGG: mex:Mext_1621 hypothetical protein; hypothetical protein 1962168 7116718 Mchl_1903 Methylobacterium extorquens CM4 hypothetical protein YP_002420694.1 1961887 D 440085 CDS YP_002420695.1 218529879 7116719 complement(1962200..1963051) 1 NC_011757.1 KEGG: mex:Mext_1622 hypothetical protein; hypothetical protein 1963051 7116719 Mchl_1904 Methylobacterium extorquens CM4 hypothetical protein YP_002420695.1 1962200 R 440085 CDS YP_002420696.1 218529880 7116720 1963111..1964340 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1623 glycosyl transferase group 1; group 1 glycosyl transferase 1964340 7116720 Mchl_1905 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002420696.1 1963111 D 440085 CDS YP_002420697.1 218529881 7116721 1964517..1965038 1 NC_011757.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1965038 infC 7116721 infC Methylobacterium extorquens CM4 translation initiation factor IF-3 YP_002420697.1 1964517 D 440085 CDS YP_002420698.1 218529882 7116722 complement(1965230..1967566) 1 NC_011757.1 PFAM: amylo-alpha-16-glucosidase; KEGG: mex:Mext_1625 amylo-alpha-16-glucosidase; amylo-alpha-16-glucosidase 1967566 7116722 Mchl_1907 Methylobacterium extorquens CM4 amylo-alpha-16-glucosidase YP_002420698.1 1965230 R 440085 CDS YP_002420699.1 218529883 7116723 complement(1967725..1968858) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1626 glycosyl transferase group 1; group 1 glycosyl transferase 1968858 7116723 Mchl_1908 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002420699.1 1967725 R 440085 CDS YP_002420700.1 218529884 7116724 1969313..1969516 1 NC_011757.1 PFAM: ribosomal protein L35; KEGG: mex:Mext_1627 50S ribosomal protein L35; 50S ribosomal protein L35 1969516 rpmI 7116724 rpmI Methylobacterium extorquens CM4 50S ribosomal protein L35 YP_002420700.1 1969313 D 440085 CDS YP_002420701.1 218529885 7116725 1969569..1969934 1 NC_011757.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1969934 rplT 7116725 rplT Methylobacterium extorquens CM4 50S ribosomal protein L20 YP_002420701.1 1969569 D 440085 CDS YP_002420702.1 218529886 7116726 1970118..1971197 1 NC_011757.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1971197 pheS 7116726 pheS Methylobacterium extorquens CM4 phenylalanyl-tRNA synthetase subunit alpha YP_002420702.1 1970118 D 440085 CDS YP_002420703.1 218529887 7116727 1971262..1973814 1 NC_011757.1 KEGG: mex:Mext_1630 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase subunit beta; phenylalanyl-tRNA synthetase subunit beta 1973814 7116727 Mchl_1912 Methylobacterium extorquens CM4 phenylalanyl-tRNA synthetase subunit beta YP_002420703.1 1971262 D 440085 CDS YP_002420704.1 218529888 7116728 1973840..1974715 1 NC_011757.1 PFAM: SEC-C motif domain protein; KEGG: mex:Mext_1631 SecC motif-containing protein; SEC-C motif domain-containing protein 1974715 7116728 Mchl_1913 Methylobacterium extorquens CM4 SEC-C motif domain-containing protein YP_002420704.1 1973840 D 440085 CDS YP_002420705.1 218529889 7116729 complement(1974663..1975490) 1 NC_011757.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein; UBA/THIF-type NAD/FAD binding protein 1975490 7116729 Mchl_1914 Methylobacterium extorquens CM4 UBA/THIF-type NAD/FAD binding protein YP_002420705.1 1974663 R 440085 CDS YP_002420706.1 218529890 7116730 1975756..1976922 1 NC_011757.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1976922 7116730 Mchl_1915 Methylobacterium extorquens CM4 succinyl-diaminopimelate desuccinylase YP_002420706.1 1975756 D 440085 CDS YP_002420707.1 218529891 7116731 complement(1976977..1977729) 1 NC_011757.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1977729 truA 7116731 truA Methylobacterium extorquens CM4 tRNA pseudouridine synthase A YP_002420707.1 1976977 R 440085 CDS YP_002420708.1 218529892 7116732 complement(1977743..1978672) 1 NC_011757.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: mex:Mext_1635 methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 1978672 7116732 Mchl_1917 Methylobacterium extorquens CM4 methionyl-tRNA formyltransferase YP_002420708.1 1977743 R 440085 CDS YP_002420709.1 218529893 7116733 complement(1978683..1979198) 1 NC_011757.1 KEGG: mex:Mext_1636 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase; peptide deformylase 1979198 7116733 Mchl_1918 Methylobacterium extorquens CM4 peptide deformylase YP_002420709.1 1978683 R 440085 CDS YP_002420710.1 218529894 7116734 complement(1979477..1980757) 1 NC_011757.1 KEGG: mex:Mext_1637 hypothetical protein; hypothetical protein 1980757 7116734 Mchl_1919 Methylobacterium extorquens CM4 hypothetical protein YP_002420710.1 1979477 R 440085 CDS YP_002420711.1 218529895 7116735 complement(1980878..1981483) 1 NC_011757.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1981483 recR 7116735 recR Methylobacterium extorquens CM4 recombination protein RecR YP_002420711.1 1980878 R 440085 CDS YP_002420712.1 218529896 7116736 1981811..1983430 1 NC_011757.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1983430 7116736 Mchl_1921 Methylobacterium extorquens CM4 phosphoenolpyruvate carboxykinase YP_002420712.1 1981811 D 440085 CDS YP_002420713.1 218529897 7116737 complement(1983476..1984753) 1 NC_011757.1 TIGRFAM:radical SAM protein; PFAM: radical SAM domain protein; KEGG: mex:Mext_1640 radical SAM protein; radical SAM enzyme, Cfr family 1984753 7116737 Mchl_1922 Methylobacterium extorquens CM4 radical SAM enzyme, Cfr family YP_002420713.1 1983476 R 440085 CDS YP_002420714.1 218529898 7116738 complement(1984870..1986609) 1 NC_011757.1 PFAM: shikimate kinase; 3-dehydroquinate synthase; KEGG: mex:Mext_1641 shikimate kinase, 3-dehydroquinate synthase; shikimate kinase., 3-dehydroquinate synthase 1986609 7116738 Mchl_1923 Methylobacterium extorquens CM4 shikimate kinase., 3-dehydroquinate synthase YP_002420714.1 1984870 R 440085 CDS YP_002420715.1 218529899 7116739 1986861..1987592 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1642 regulatory protein TetR; TetR family transcriptional regulator 1987592 7116739 Mchl_1924 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420715.1 1986861 D 440085 CDS YP_002420716.1 218529900 7116740 1987943..1988905 1 NC_011757.1 TIGRFAM: malate dehydrogenase, NAD-dependent; PFAM: lactate/malate dehydrogenase; KEGG: mex:Mext_1643 malate dehydrogenase, NAD-dependent; malate dehydrogenase, NAD-dependent 1988905 7116740 Mchl_1925 Methylobacterium extorquens CM4 malate dehydrogenase, NAD-dependent YP_002420716.1 1987943 D 440085 CDS YP_002420717.1 218529901 7116741 1988983..1990179 1 NC_011757.1 KEGG: mex:Mext_1644 succinyl-CoA synthetase, beta subunit; TIGRFAM: succinyl-CoA synthetase subunit beta; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; succinyl-CoA synthetase subunit beta 1990179 7116741 Mchl_1926 Methylobacterium extorquens CM4 succinyl-CoA synthetase subunit beta YP_002420717.1 1988983 D 440085 CDS YP_002420718.1 218529902 7116742 1990188..1991075 1 NC_011757.1 TIGRFAM: succinyl-CoA synthetase, subunit alpha; PFAM: CoA-binding protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: mex:Mext_1645 succinyl-CoA synthetase, subunit alpha; succinyl-CoA synthetase subunit alpha 1991075 7116742 Mchl_1927 Methylobacterium extorquens CM4 succinyl-CoA synthetase subunit alpha YP_002420718.1 1990188 D 440085 CDS YP_002420719.1 218529903 7116743 1991300..1994290 1 NC_011757.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1994290 sucA 7116743 sucA Methylobacterium extorquens CM4 2-oxoglutarate dehydrogenase E1 component YP_002420719.1 1991300 D 440085 CDS YP_002420720.1 218529904 7116744 1994374..1995702 1 NC_011757.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: mex:Mext_1647 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase 1995702 7116744 Mchl_1929 Methylobacterium extorquens CM4 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_002420720.1 1994374 D 440085 CDS YP_002420721.1 218529905 7116745 1995991..1997394 1 NC_011757.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1997394 7116745 Mchl_1930 Methylobacterium extorquens CM4 dihydrolipoamide dehydrogenase YP_002420721.1 1995991 D 440085 CDS YP_002420722.1 218529906 7116746 1997594..1999219 1 NC_011757.1 KEGG: mex:Mext_1649 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; histidine kinase 1999219 7116746 Mchl_1931 Methylobacterium extorquens CM4 histidine kinase YP_002420722.1 1997594 D 440085 CDS YP_002420723.1 218529907 7116747 1999279..1999899 1 NC_011757.1 KEGG: mex:Mext_1650 hypothetical protein; hypothetical protein 1999899 7116747 Mchl_1932 Methylobacterium extorquens CM4 hypothetical protein YP_002420723.1 1999279 D 440085 CDS YP_002420724.1 218529908 7116748 complement(1999881..2000510) 1 NC_011757.1 PFAM: sarcosine oxidase subunit gamma; KEGG: mex:Mext_1651 sarcosine oxidase subunit gamma; sarcosine oxidase subunit gamma 2000510 7116748 Mchl_1933 Methylobacterium extorquens CM4 sarcosine oxidase subunit gamma YP_002420724.1 1999881 R 440085 CDS YP_002420725.1 218529909 7116749 complement(2000503..2003529) 1 NC_011757.1 TIGRFAM: sarcosine oxidase subunit alpha family; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: mex:Mext_1652 sarcosine oxidase subunit alpha family protein; sarcosine oxidase subunit alpha family 2003529 7116749 Mchl_1934 Methylobacterium extorquens CM4 sarcosine oxidase subunit alpha family YP_002420725.1 2000503 R 440085 CDS YP_002420726.1 218529910 7116750 complement(2003526..2003813) 1 NC_011757.1 PFAM: sarcosine oxidase subunit delta heterotetrameric; KEGG: mex:Mext_1653 sarcosine oxidase subunit delta heterotetrameric; sarcosine oxidase subunit delta heterotetrameric 2003813 7116750 Mchl_1935 Methylobacterium extorquens CM4 sarcosine oxidase subunit delta heterotetrameric YP_002420726.1 2003526 R 440085 CDS YP_002420727.1 218529911 7116751 complement(2003931..2005181) 1 NC_011757.1 TIGRFAM: sarcosine oxidase subunit beta family; PFAM: FAD dependent oxidoreductase; KEGG: mex:Mext_1654 sarcosine oxidase subunit beta family protein; sarcosine oxidase subunit beta family 2005181 7116751 Mchl_1936 Methylobacterium extorquens CM4 sarcosine oxidase subunit beta family YP_002420727.1 2003931 R 440085 CDS YP_002420728.1 218529912 7116752 2005382..2006377 1 NC_011757.1 PFAM: ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_1655 ThiJ/PfpI domain-containing protein; AraC family transcriptional regulator 2006377 7116752 Mchl_1937 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002420728.1 2005382 D 440085 CDS YP_002420729.1 218529913 7116753 2006857..2007792 1 NC_011757.1 PFAM: glutamine amidotransferase class-II; KEGG: mex:Mext_1656 glutamine amidotransferase class-II; class II glutamine amidotransferase 2007792 7116753 Mchl_1938 Methylobacterium extorquens CM4 class II glutamine amidotransferase YP_002420729.1 2006857 D 440085 CDS YP_002420730.1 218529914 7116754 2007792..2008481 1 NC_011757.1 PFAM: glutamate synthase subunit alpha domain protein; KEGG: mex:Mext_1657 glutamate synthase subunit alpha; glutamate synthase subunit alpha domain-containing protein 2008481 7116754 Mchl_1939 Methylobacterium extorquens CM4 glutamate synthase subunit alpha domain-containing protein YP_002420730.1 2007792 D 440085 CDS YP_002420731.1 218529915 7116755 2008481..2009824 1 NC_011757.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: mex:Mext_1658 ferredoxin-dependent glutamate synthase; ferredoxin-dependent glutamate synthase 2009824 7116755 Mchl_1940 Methylobacterium extorquens CM4 ferredoxin-dependent glutamate synthase YP_002420731.1 2008481 D 440085 CDS YP_002420732.1 218529916 7116756 2009914..2011212 1 NC_011757.1 TIGRFAM: glutamine synthetaseII; PFAM: glutamine synthetase catalytic region; KEGG: mex:Mext_1659 glutamine synthetase, type III; glutamine synthetaseII 2011212 7116756 Mchl_1941 Methylobacterium extorquens CM4 glutamine synthetaseII YP_002420732.1 2009914 D 440085 CDS YP_002420733.1 218529917 7116757 2011400..2011906 1 NC_011757.1 KEGG: mex:Mext_1660 hypothetical protein; hypothetical protein 2011906 7116757 Mchl_1942 Methylobacterium extorquens CM4 hypothetical protein YP_002420733.1 2011400 D 440085 CDS YP_002420734.1 218529918 7116759 2012362..2012655 1 NC_011757.1 KEGG: mpo:Mpop_0195 hypothetical protein; hypothetical protein 2012655 7116759 Mchl_1943 Methylobacterium extorquens CM4 hypothetical protein YP_002420734.1 2012362 D 440085 CDS YP_002420735.1 218529919 7116760 complement(2012853..2013158) 1 NC_011757.1 hypothetical protein 2013158 7116760 Mchl_1944 Methylobacterium extorquens CM4 hypothetical protein YP_002420735.1 2012853 R 440085 CDS YP_002420736.1 218529920 7116761 complement(2013328..2013522) 1 NC_011757.1 hypothetical protein 2013522 7116761 Mchl_1945 Methylobacterium extorquens CM4 hypothetical protein YP_002420736.1 2013328 R 440085 CDS YP_002420737.1 218529921 7116762 complement(2013515..2013883) 1 NC_011757.1 hypothetical protein 2013883 7116762 Mchl_1946 Methylobacterium extorquens CM4 hypothetical protein YP_002420737.1 2013515 R 440085 CDS YP_002420738.1 218529922 7116763 complement(2013886..2014266) 1 NC_011757.1 KEGG: mrd:Mrad2831_5308 hypothetical protein; hypothetical protein 2014266 7116763 Mchl_1947 Methylobacterium extorquens CM4 hypothetical protein YP_002420738.1 2013886 R 440085 CDS YP_002420739.1 218529923 7116764 2014554..2015195 1 NC_011757.1 KEGG: mrd:Mrad2831_2658 hypothetical protein; hypothetical protein 2015195 7116764 Mchl_1948 Methylobacterium extorquens CM4 hypothetical protein YP_002420739.1 2014554 D 440085 CDS YP_002420740.1 218529924 7116765 complement(2015338..2016729) 1 NC_011757.1 PFAM: protein of unknown function DUF1311; KEGG: bcm:Bcenmc03_7075 lipoprotein-like protein; hypothetical protein 2016729 7116765 Mchl_1949 Methylobacterium extorquens CM4 hypothetical protein YP_002420740.1 2015338 R 440085 CDS YP_002420741.1 218529925 7116766 2016907..2017629 1 NC_011757.1 PFAM: cell wall hydrolase/autolysin; KEGG: mag:amb4081 N-acetylmuramoyl-L-alanine amidase; cell wall hydrolase/autolysin 2017629 7116766 Mchl_1950 Methylobacterium extorquens CM4 cell wall hydrolase/autolysin YP_002420741.1 2016907 D 440085 CDS YP_002420742.1 218529926 7116769 2019313..2020449 1 NC_011757.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: cti:pRALTA_0502 transposase, IS110 family; transposase IS116/IS110/IS902 family protein 2020449 7116769 Mchl_1953 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002420742.1 2019313 D 440085 CDS YP_002420743.1 218529927 7116777 complement(2028070..2029578) 1 NC_011757.1 KEGG: bbt:BBta_5464 caspase domain-containing protein; hypothetical protein 2029578 7116777 Mchl_1961 Methylobacterium extorquens CM4 hypothetical protein YP_002420743.1 2028070 R 440085 CDS YP_002420744.1 218529928 7116778 complement(2029581..2030624) 1 NC_011757.1 KEGG: dsh:Dshi_0899 hypothetical protein; hypothetical protein 2030624 7116778 Mchl_1962 Methylobacterium extorquens CM4 hypothetical protein YP_002420744.1 2029581 R 440085 CDS YP_002420745.1 218529929 7116779 complement(2030631..2033219) 1 NC_011757.1 KEGG: mlo:mll9170 virulence factor SrfC-like protein; virulence factor SrfC-like protein 2033219 7116779 Mchl_1963 Methylobacterium extorquens CM4 virulence factor SrfC-like protein YP_002420745.1 2030631 R 440085 CDS YP_002420746.1 218529930 7116780 complement(2033242..2036370) 1 NC_011757.1 PFAM: virulence protein SrfB; KEGG: mlo:mll9171 virulence factor SrfB-like protein; virulence protein SrfB 2036370 7116780 Mchl_1964 Methylobacterium extorquens CM4 virulence protein SrfB YP_002420746.1 2033242 R 440085 CDS YP_002420747.1 218529931 7116781 complement(2036378..2037838) 1 NC_011757.1 KEGG: rde:RD1_1019 hypothetical protein; hypothetical protein 2037838 7116781 Mchl_1965 Methylobacterium extorquens CM4 hypothetical protein YP_002420747.1 2036378 R 440085 CDS YP_002420748.1 218529932 7116782 complement(2037851..2039587) 1 NC_011757.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: dsh:Dshi_0895 peptidase S1 and S6 chymotrypsin/Hap; peptidase S1 and S6 chymotrypsin/Hap 2039587 7116782 Mchl_1966 Methylobacterium extorquens CM4 peptidase S1 and S6 chymotrypsin/Hap YP_002420748.1 2037851 R 440085 CDS YP_002420749.1 218529933 7116783 complement(2039939..2041219) 1 NC_011757.1 KEGG: nwi:Nwi_1274 peptidase C14, caspase catalytic subunit P20; hypothetical protein 2041219 7116783 Mchl_1967 Methylobacterium extorquens CM4 hypothetical protein YP_002420749.1 2039939 R 440085 CDS YP_002420750.1 218529934 7116787 2043229..2044653 1 NC_011757.1 hypothetical protein 2044653 7116787 Mchl_1971 Methylobacterium extorquens CM4 hypothetical protein YP_002420750.1 2043229 D 440085 CDS YP_002420751.1 218529935 7116788 2044658..2045320 1 NC_011757.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; KEGG: aoe:Clos_0160 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; N-acetylmuramoyl-L-alanine amidase family 2 2045320 7116788 Mchl_1972 Methylobacterium extorquens CM4 N-acetylmuramoyl-L-alanine amidase family 2 YP_002420751.1 2044658 D 440085 CDS YP_002420752.1 218529936 7116789 2046403..2046642 1 NC_011757.1 hypothetical protein 2046642 7116789 Mchl_1973 Methylobacterium extorquens CM4 hypothetical protein YP_002420752.1 2046403 D 440085 CDS YP_002420753.1 218529937 7116790 complement(2046753..2048210) 1 NC_011757.1 TIGRFAM: phage/plasmid primase, P4 family; PFAM: primase P4; KEGG: mrd:Mrad2831_5167 P4 family phage/plasmid primase; hypothetical protein 2048210 7116790 Mchl_1974 Methylobacterium extorquens CM4 hypothetical protein YP_002420753.1 2046753 R 440085 CDS YP_002420754.1 218529938 7116791 complement(2048222..2048497) 1 NC_011757.1 hypothetical protein 2048497 7116791 Mchl_1975 Methylobacterium extorquens CM4 hypothetical protein YP_002420754.1 2048222 R 440085 CDS YP_002420755.1 218529939 7116792 complement(2048494..2048709) 1 NC_011757.1 KEGG: mrd:Mrad2831_5164 hypothetical protein; hypothetical protein 2048709 7116792 Mchl_1976 Methylobacterium extorquens CM4 hypothetical protein YP_002420755.1 2048494 R 440085 CDS YP_002420756.1 218529940 7116795 complement(2048905..2050428) 1 NC_011757.1 KEGG: mrd:Mrad2831_5192 hypothetical protein; hypothetical protein 2050428 7116795 Mchl_1977 Methylobacterium extorquens CM4 hypothetical protein YP_002420756.1 2048905 R 440085 CDS YP_002420757.1 218529941 7118679 2051560..2062323 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; Animal haem peroxidase; KEGG: mex:Mext_1662 heme peroxidase; heme peroxidase 2062323 7118679 Mchl_1979 Methylobacterium extorquens CM4 heme peroxidase YP_002420757.1 2051560 D 440085 CDS YP_002420758.1 218529942 7118680 2062384..2064150 1 NC_011757.1 KEGG: mex:Mext_1663 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; type I secretion system ATPase 2064150 7118680 Mchl_1980 Methylobacterium extorquens CM4 type I secretion system ATPase YP_002420758.1 2062384 D 440085 CDS YP_002420759.1 218529943 7118681 2064147..2066351 1 NC_011757.1 KEGG: mex:Mext_1664 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 2066351 7118681 Mchl_1981 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002420759.1 2064147 D 440085 CDS YP_002420760.1 218529944 7118682 2066373..2067719 1 NC_011757.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD; KEGG: mex:Mext_1665 HlyD family type I secretion membrane fusion protein; HlyD family type I secretion membrane fusion protein 2067719 7118682 Mchl_1982 Methylobacterium extorquens CM4 HlyD family type I secretion membrane fusion protein YP_002420760.1 2066373 D 440085 CDS YP_002420761.1 218529945 7118683 2067891..2068430 1 NC_011757.1 KEGG: mex:Mext_1666 hypothetical protein; transcriptional regulator 2068430 7118683 Mchl_1983 Methylobacterium extorquens CM4 transcriptional regulator YP_002420761.1 2067891 D 440085 CDS YP_002420762.1 218529946 7118684 2068480..2069601 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mex:Mext_1667 ATPase domain-containing protein; histidine kinase 2069601 7118684 Mchl_1984 Methylobacterium extorquens CM4 histidine kinase YP_002420762.1 2068480 D 440085 CDS YP_002420763.1 218529947 7118685 2069594..2070262 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: mex:Mext_1668 response regulator receiver; LuxR family transcriptional regulator 2070262 7118685 Mchl_1985 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002420763.1 2069594 D 440085 CDS YP_002420764.1 218529948 7118687 complement(2070434..2071501) 1 NC_011757.1 KEGG: mex:Mext_1669 esterase/lipase-like protein; esterase/lipase-like protein 2071501 7118687 Mchl_1987 Methylobacterium extorquens CM4 esterase/lipase-like protein YP_002420764.1 2070434 R 440085 CDS YP_002420765.1 218529949 7118688 complement(2071601..2072410) 1 NC_011757.1 PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_1670 methyltransferase type 11; type 11 methyltransferase 2072410 7118688 Mchl_1988 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002420765.1 2071601 R 440085 CDS YP_002420766.1 218529950 7118689 2073066..2078879 1 NC_011757.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_1671 histidine kinase; GAF sensor hybrid histidine kinase 2078879 7118689 Mchl_1989 Methylobacterium extorquens CM4 GAF sensor hybrid histidine kinase YP_002420766.1 2073066 D 440085 CDS YP_002420767.1 218529951 7118690 2078876..2080963 1 NC_011757.1 KEGG: mex:Mext_1672 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; SMART: PAC repeat-containing protein; multi-sensor hybrid histidine kinase 2080963 7118690 Mchl_1990 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002420767.1 2078876 D 440085 CDS YP_002420768.1 218529952 7118691 complement(2081234..2082106) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; TrkA-N domain protein; NmrA family protein; KEGG: mex:Mext_1673 NmrA family protein; NmrA family protein 2082106 7118691 Mchl_1991 Methylobacterium extorquens CM4 NmrA family protein YP_002420768.1 2081234 R 440085 CDS YP_002420769.1 218529953 7118692 2082210..2083103 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1674 LysR substrate-binding; LysR family transcriptional regulator 2083103 7118692 Mchl_1992 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420769.1 2082210 D 440085 CDS YP_002420770.1 218529954 7118693 complement(2083227..2084273) 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_1675 luciferase family protein; monooxygenase 2084273 7118693 Mchl_1993 Methylobacterium extorquens CM4 monooxygenase YP_002420770.1 2083227 R 440085 CDS YP_002420771.1 218529955 7118695 complement(2084730..2085128) 1 NC_011757.1 PFAM: DoxX family protein; KEGG: mex:Mext_1676 DoxX family protein; DoxX family protein 2085128 7118695 Mchl_1995 Methylobacterium extorquens CM4 DoxX family protein YP_002420771.1 2084730 R 440085 CDS YP_002420772.1 218529956 7118696 2085254..2086144 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1677 LysR substrate-binding; LysR family transcriptional regulator 2086144 7118696 Mchl_1996 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420772.1 2085254 D 440085 CDS YP_002420773.1 218529957 7118697 complement(2086635..2087288) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_1678 isochorismatase hydrolase; isochorismatase hydrolase 2087288 7118697 Mchl_1997 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002420773.1 2086635 R 440085 CDS YP_002420774.1 218529958 7118698 complement(2087391..2088347) 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_1679 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 2088347 7118698 Mchl_1998 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002420774.1 2087391 R 440085 CDS YP_002420775.1 218529959 7118699 2088443..2089381 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1680 LysR substrate-binding; LysR family transcriptional regulator 2089381 7118699 Mchl_1999 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420775.1 2088443 D 440085 CDS YP_002420776.1 218529960 7118700 complement(2089967..2090341) 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_1681 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2090341 7118700 Mchl_2000 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002420776.1 2089967 R 440085 CDS YP_002420777.1 218529961 7118701 2091050..2091844 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_1682 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 2091844 7118701 Mchl_2001 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002420777.1 2091050 D 440085 CDS YP_002420778.1 218529962 7118702 2091907..2092785 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1683 LysR substrate-binding; LysR family transcriptional regulator 2092785 7118702 Mchl_2002 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420778.1 2091907 D 440085 CDS YP_002420779.1 218529963 7118703 2092869..2093165 1 NC_011757.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: mex:Mext_1684 antibiotic biosynthesis monooxygenase; antibiotic biosynthesis monooxygenase 2093165 7118703 Mchl_2003 Methylobacterium extorquens CM4 antibiotic biosynthesis monooxygenase YP_002420779.1 2092869 D 440085 CDS YP_002420780.1 218529964 7118704 complement(2093238..2093663) 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_1685 cupin 2 domain-containing protein; cupin 2093663 7118704 Mchl_2004 Methylobacterium extorquens CM4 cupin YP_002420780.1 2093238 R 440085 CDS YP_002420781.1 218529965 7118706 complement(2094116..2095132) 1 NC_011757.1 KEGG: mex:Mext_1687 zinc-binding alcohol dehydrogenase family protein; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; zinc-binding alcohol dehydrogenase family protein 2095132 7118706 Mchl_2006 Methylobacterium extorquens CM4 zinc-binding alcohol dehydrogenase family protein YP_002420781.1 2094116 R 440085 CDS YP_002420782.1 218529966 7118707 complement(2095160..2096071) 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_1688 hypothetical protein; hypothetical protein 2096071 7118707 Mchl_2007 Methylobacterium extorquens CM4 hypothetical protein YP_002420782.1 2095160 R 440085 CDS YP_002420783.1 218529967 7118708 2096733..2098457 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_1689 diguanylate cyclase; diguanylate cyclase 2098457 7118708 Mchl_2008 Methylobacterium extorquens CM4 diguanylate cyclase YP_002420783.1 2096733 D 440085 CDS YP_002420784.1 218529968 7118709 complement(2099497..2104917) 1 NC_011757.1 TIGRFAM: autotransporter-associated beta strand repeat protein; PFAM: amidase; KEGG: mex:Mext_1690 beta strand repeat-containing protein; autotransporter-associated beta strand repeat-containing protein 2104917 7118709 Mchl_2009 Methylobacterium extorquens CM4 autotransporter-associated beta strand repeat-containing protein YP_002420784.1 2099497 R 440085 CDS YP_002420785.1 218529969 7118710 2105563..2106963 1 NC_011757.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: mex:Mext_1691 xanthine permease; xanthine permease 2106963 7118710 Mchl_2010 Methylobacterium extorquens CM4 xanthine permease YP_002420785.1 2105563 D 440085 CDS YP_002420786.1 218529970 7118711 complement(2107090..2107497) 1 NC_011757.1 KEGG: mex:Mext_1692 hypothetical protein; hypothetical protein 2107497 7118711 Mchl_2011 Methylobacterium extorquens CM4 hypothetical protein YP_002420786.1 2107090 R 440085 CDS YP_002420787.1 218529971 7118712 complement(2107494..2108909) 1 NC_011757.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 2108909 7118712 Mchl_2012 Methylobacterium extorquens CM4 amidase YP_002420787.1 2107494 R 440085 CDS YP_002420788.1 218529972 7118713 complement(2108906..2109109) 1 NC_011757.1 KEGG: mex:Mext_1694 hypothetical protein; hypothetical protein 2109109 7118713 Mchl_2013 Methylobacterium extorquens CM4 hypothetical protein YP_002420788.1 2108906 R 440085 CDS YP_002420789.1 218529973 7118714 complement(2109212..2109892) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_1695 isochorismatase hydrolase; isochorismatase hydrolase 2109892 7118714 Mchl_2014 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002420789.1 2109212 R 440085 CDS YP_002420790.1 218529974 7118715 2110398..2111393 1 NC_011757.1 KEGG: mex:Mext_1696 signal peptide; signal peptide 2111393 7118715 Mchl_2015 Methylobacterium extorquens CM4 signal peptide YP_002420790.1 2110398 D 440085 CDS YP_002420791.1 218529975 7118716 2111419..2112783 1 NC_011757.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.; hydroxydechloroatrazine ethylaminohydrolase 2112783 7118716 Mchl_2016 Methylobacterium extorquens CM4 hydroxydechloroatrazine ethylaminohydrolase YP_002420791.1 2111419 D 440085 CDS YP_002420792.1 218529976 7118717 2112783..2114387 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1698 ABC transporter; ABC transporter 2114387 7118717 Mchl_2017 Methylobacterium extorquens CM4 ABC transporter YP_002420792.1 2112783 D 440085 CDS YP_002420793.1 218529977 7118718 2114449..2115540 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1699 inner-membrane translocator; inner-membrane translocator 2115540 7118718 Mchl_2018 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420793.1 2114449 D 440085 CDS YP_002420794.1 218529978 7118719 2115537..2116463 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1700 inner-membrane translocator; inner-membrane translocator 2116463 7118719 Mchl_2019 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420794.1 2115537 D 440085 CDS YP_002420795.1 218529979 7118720 2116662..2117768 1 NC_011757.1 PFAM: basic membrane lipoprotein; KEGG: mex:Mext_1701 basic membrane lipoprotein; basic membrane lipoprotein 2117768 7118720 Mchl_2020 Methylobacterium extorquens CM4 basic membrane lipoprotein YP_002420795.1 2116662 D 440085 CDS YP_002420796.1 218529980 7118721 2117942..2119099 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1702 inner-membrane translocator; inner-membrane translocator 2119099 7118721 Mchl_2021 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420796.1 2117942 D 440085 CDS YP_002420797.1 218529981 7118722 2119122..2120042 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_1703 inner-membrane translocator; inner-membrane translocator 2120042 7118722 Mchl_2022 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420797.1 2119122 D 440085 CDS YP_002420798.1 218529982 7118723 2120052..2121080 1 NC_011757.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 2121080 amiF 7118723 amiF Methylobacterium extorquens CM4 formamidase YP_002420798.1 2120052 D 440085 CDS YP_002420799.1 218529983 7118724 2121077..2121796 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_1705 isochorismatase hydrolase; isochorismatase hydrolase 2121796 7118724 Mchl_2024 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002420799.1 2121077 D 440085 CDS YP_002420800.1 218529984 7118725 2121804..2123366 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1706 ABC transporter; ABC transporter 2123366 7118725 Mchl_2025 Methylobacterium extorquens CM4 ABC transporter YP_002420800.1 2121804 D 440085 CDS YP_002420801.1 218529985 7118726 complement(2123682..2124494) 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_1707 hypothetical protein; hypothetical protein 2124494 7118726 Mchl_2026 Methylobacterium extorquens CM4 hypothetical protein YP_002420801.1 2123682 R 440085 CDS YP_002420802.1 218529986 7118727 2124622..2125902 1 NC_011757.1 PFAM: basic membrane lipoprotein; KEGG: mex:Mext_1708 basic membrane lipoprotein; basic membrane lipoprotein 2125902 7118727 Mchl_2027 Methylobacterium extorquens CM4 basic membrane lipoprotein YP_002420802.1 2124622 D 440085 CDS YP_002420803.1 218529987 7118728 complement(2125979..2126260) 1 NC_011757.1 KEGG: mex:Mext_1709 hypothetical protein; hypothetical protein 2126260 7118728 Mchl_2028 Methylobacterium extorquens CM4 hypothetical protein YP_002420803.1 2125979 R 440085 CDS YP_002420804.1 218529988 7118729 complement(2126332..2126538) 1 NC_011757.1 KEGG: mex:Mext_1710 hypothetical protein; hypothetical protein 2126538 7118729 Mchl_2029 Methylobacterium extorquens CM4 hypothetical protein YP_002420804.1 2126332 R 440085 CDS YP_002420805.1 218529989 7118730 complement(2126627..2128270) 1 NC_011757.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase domain protein; KEGG: mex:Mext_1711 peptidase S15; peptidase S15 2128270 7118730 Mchl_2030 Methylobacterium extorquens CM4 peptidase S15 YP_002420805.1 2126627 R 440085 CDS YP_002420806.1 218529990 7118731 complement(2128260..2129078) 1 NC_011757.1 PFAM: creatininase; KEGG: mex:Mext_1712 creatininase; creatininase 2129078 7118731 Mchl_2031 Methylobacterium extorquens CM4 creatininase YP_002420806.1 2128260 R 440085 CDS YP_002420807.1 218529991 7118732 complement(2129078..2130637) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_1713 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 2130637 7118732 Mchl_2032 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002420807.1 2129078 R 440085 CDS YP_002420808.1 218529992 7118733 complement(2130677..2131264) 1 NC_011757.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mex:Mext_1714 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 2131264 7118733 Mchl_2033 Methylobacterium extorquens CM4 NAD(P)H dehydrogenase (quinone) YP_002420808.1 2130677 R 440085 CDS YP_002420809.1 218529993 7118734 complement(2131261..2132649) 1 NC_011757.1 PFAM: FAD linked oxidase; KEGG: mex:Mext_1715 FAD linked oxidase domain-containing protein; FAD linked oxidase 2132649 7118734 Mchl_2034 Methylobacterium extorquens CM4 FAD linked oxidase YP_002420809.1 2131261 R 440085 CDS YP_002420810.1 218529994 7118735 complement(2132651..2133622) 1 NC_011757.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: mex:Mext_1716 2OG-Fe(II) oxygenase; 2OG-Fe(II) oxygenase 2133622 7118735 Mchl_2035 Methylobacterium extorquens CM4 2OG-Fe(II) oxygenase YP_002420810.1 2132651 R 440085 CDS YP_002420811.1 218529995 7118736 complement(2133635..2134603) 1 NC_011757.1 PFAM: NMT1/THI5 like domain protein; KEGG: mex:Mext_1717 NMT1/THI5-like domain-containing protein; NMT1/THI5 like domain-containing protein 2134603 7118736 Mchl_2036 Methylobacterium extorquens CM4 NMT1/THI5 like domain-containing protein YP_002420811.1 2133635 R 440085 CDS YP_002420812.1 218529996 7118737 complement(2134603..2135676) 1 NC_011757.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mex:Mext_1718 Rieske (2Fe-2S) domain-containing protein; Rieske (2Fe-2S) domain-containing protein 2135676 7118737 Mchl_2037 Methylobacterium extorquens CM4 Rieske (2Fe-2S) domain-containing protein YP_002420812.1 2134603 R 440085 CDS YP_002420813.1 218529997 7118738 complement(2135743..2136537) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1719 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 2136537 7118738 Mchl_2038 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420813.1 2135743 R 440085 CDS YP_002420814.1 218529998 7118739 complement(2136534..2137454) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1720 ABC transporter; ABC transporter 2137454 7118739 Mchl_2039 Methylobacterium extorquens CM4 ABC transporter YP_002420814.1 2136534 R 440085 CDS YP_002420815.1 218529999 7118740 complement(2137463..2138449) 1 NC_011757.1 PFAM: NMT1/THI5 like domain protein; KEGG: mex:Mext_1721 NMT1/THI5-like domain-containing protein; NMT1/THI5 like domain-containing protein 2138449 7118740 Mchl_2040 Methylobacterium extorquens CM4 NMT1/THI5 like domain-containing protein YP_002420815.1 2137463 R 440085 CDS YP_002420816.1 218530000 7118741 2138776..2139681 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1722 LysR substrate-binding; LysR family transcriptional regulator 2139681 7118741 Mchl_2041 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420816.1 2138776 D 440085 CDS YP_002420817.1 218530001 7118742 2139760..2141127 1 NC_011757.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase-like protein 2141127 7118742 Mchl_2042 Methylobacterium extorquens CM4 cytosine deaminase-like protein YP_002420817.1 2139760 D 440085 CDS YP_002420818.1 218530002 7118743 2141422..2141670 1 NC_011757.1 KEGG: mex:Mext_1724 hypothetical protein; hypothetical protein 2141670 7118743 Mchl_2043 Methylobacterium extorquens CM4 hypothetical protein YP_002420818.1 2141422 D 440085 CDS YP_002420819.1 218530003 7118744 2141939..2142169 1 NC_011757.1 KEGG: mex:Mext_1725 hypothetical protein; hypothetical protein 2142169 7118744 Mchl_2044 Methylobacterium extorquens CM4 hypothetical protein YP_002420819.1 2141939 D 440085 CDS YP_002420820.1 218530004 7118745 2142349..2143272 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1726 LysR substrate-binding; LysR family transcriptional regulator 2143272 7118745 Mchl_2045 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420820.1 2142349 D 440085 CDS YP_002420821.1 218530005 7118746 complement(2143300..2144658) 1 NC_011757.1 TIGRFAM: guanine deaminase; PFAM: amidohydrolase; amidohydrolase; KEGG: mex:Mext_1727 guanine deaminase; guanine deaminase 2144658 7118746 Mchl_2046 Methylobacterium extorquens CM4 guanine deaminase YP_002420821.1 2143300 R 440085 CDS YP_002420822.1 218530006 7118747 complement(2144655..2147435) 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_1728 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 2147435 7118747 Mchl_2047 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002420822.1 2144655 R 440085 CDS YP_002420823.1 218530007 7118748 complement(2147432..2148247) 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mex:Mext_1729 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 2148247 7118748 Mchl_2048 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002420823.1 2147432 R 440085 CDS YP_002420824.1 218530008 7118749 complement(2148572..2149576) 1 NC_011757.1 PFAM: NMT1/THI5 like domain protein; KEGG: mex:Mext_1730 NMT1/THI5-like domain-containing protein; NMT1/THI5 like domain-containing protein 2149576 7118749 Mchl_2049 Methylobacterium extorquens CM4 NMT1/THI5 like domain-containing protein YP_002420824.1 2148572 R 440085 CDS YP_002420825.1 218530009 7118750 complement(2149664..2150629) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1731 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 2150629 7118750 Mchl_2050 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420825.1 2149664 R 440085 CDS YP_002420826.1 218530010 7118751 complement(2150626..2151543) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1732 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 2151543 7118751 Mchl_2051 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002420826.1 2150626 R 440085 CDS YP_002420827.1 218530011 7118752 complement(2151533..2152387) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1733 ABC transporter; ABC transporter 2152387 7118752 Mchl_2052 Methylobacterium extorquens CM4 ABC transporter YP_002420827.1 2151533 R 440085 CDS YP_002420828.1 218530012 7118753 complement(2152586..2153191) 1 NC_011757.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: mex:Mext_1734 flavin reductase domain-containing protein; flavin reductase domain-containing FMN-binding protein 2153191 7118753 Mchl_2053 Methylobacterium extorquens CM4 flavin reductase domain-containing FMN-binding protein YP_002420828.1 2152586 R 440085 CDS YP_002420829.1 218530013 7118754 complement(2153222..2154004) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_1735 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 2154004 7118754 Mchl_2054 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002420829.1 2153222 R 440085 CDS YP_002420830.1 218530014 7118755 complement(2154009..2154401) 1 NC_011757.1 PFAM: endoribonuclease L-PSP; KEGG: mex:Mext_1736 endoribonuclease L-PSP; endoribonuclease L-PSP 2154401 7118755 Mchl_2055 Methylobacterium extorquens CM4 endoribonuclease L-PSP YP_002420830.1 2154009 R 440085 CDS YP_002420831.1 218530015 7118756 complement(2154414..2155160) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_1737 isochorismatase hydrolase; isochorismatase hydrolase 2155160 7118756 Mchl_2056 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002420831.1 2154414 R 440085 CDS YP_002420832.1 218530016 7118757 complement(2155160..2156290) 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_1738 luciferase family protein; monooxygenase 2156290 7118757 Mchl_2057 Methylobacterium extorquens CM4 monooxygenase YP_002420832.1 2155160 R 440085 CDS YP_002420833.1 218530017 7115839 complement(2156505..2157146) 1 NC_011757.1 PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: mex:Mext_1739 tetracycline transcriptional regulator YcdC domain-containing protein; TetR family transcriptional regulator 2157146 7115839 Mchl_2058 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420833.1 2156505 R 440085 CDS YP_002420834.1 218530018 7115843 complement(2157274..2157771) 1 NC_011757.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 2157771 7115843 Mchl_2059 Methylobacterium extorquens CM4 ureidoglycolate hydrolase YP_002420834.1 2157274 R 440085 CDS YP_002420835.1 218530019 7115844 complement(2157768..2158607) 1 NC_011757.1 TIGRFAM: allantoin catabolism protein; PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: mex:Mext_1741 hypothetical protein; hypothetical protein 2158607 7115844 Mchl_2060 Methylobacterium extorquens CM4 hypothetical protein YP_002420835.1 2157768 R 440085 CDS YP_002420836.1 218530020 7115845 complement(2158726..2159976) 1 NC_011757.1 PFAM: protein of unknown function DUF989; KEGG: mex:Mext_1742 hypothetical protein; hypothetical protein 2159976 7115845 Mchl_2061 Methylobacterium extorquens CM4 hypothetical protein YP_002420836.1 2158726 R 440085 CDS YP_002420837.1 218530021 7115846 2160111..2161043 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_1743 carbonate dehydratase; LysR family transcriptional regulator 2161043 7115846 Mchl_2062 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420837.1 2160111 D 440085 CDS YP_002420838.1 218530022 7115847 complement(2161076..2162488) 1 NC_011757.1 KEGG: mex:Mext_1744 urate catabolism protein; TIGRFAM: OHCU decarboxylase; urate catabolism protein; PFAM: polysaccharide deacetylase; urate catabolism protein 2162488 7115847 Mchl_2063 Methylobacterium extorquens CM4 urate catabolism protein YP_002420838.1 2161076 R 440085 CDS YP_002420839.1 218530023 7115848 2162725..2163117 1 NC_011757.1 TIGRFAM: hydroxyisourate hydrolase; PFAM: transthyretin; KEGG: mex:Mext_1745 hydroxyisourate hydrolase; hydroxyisourate hydrolase 2163117 7115848 Mchl_2064 Methylobacterium extorquens CM4 hydroxyisourate hydrolase YP_002420839.1 2162725 D 440085 CDS YP_002420840.1 218530024 7115849 complement(2163102..2163614) 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mpo:Mpop_1232 (2Fe-2S)-binding domain protein; (2Fe-2S)-binding domain-containing protein 2163614 7115849 Mchl_2065 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002420840.1 2163102 R 440085 CDS YP_002420841.1 218530025 7115850 complement(2163611..2166799) 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; molybdopterin dehydrogenase FAD-binding; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mpo:Mpop_1233 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 2166799 7115850 Mchl_2066 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002420841.1 2163611 R 440085 CDS YP_002420842.1 218530026 7115851 complement(2166852..2167712) 1 NC_011757.1 KEGG: mpo:Mpop_1234 hypothetical protein; hypothetical protein 2167712 7115851 Mchl_2067 Methylobacterium extorquens CM4 hypothetical protein YP_002420842.1 2166852 R 440085 CDS YP_002420843.1 218530027 7115852 complement(2167726..2169108) 1 NC_011757.1 PFAM: amidohydrolase; amidohydrolase; KEGG: mpo:Mpop_1235 amidohydrolase; amidohydrolase 2169108 7115852 Mchl_2068 Methylobacterium extorquens CM4 amidohydrolase YP_002420843.1 2167726 R 440085 CDS YP_002420844.1 218530028 7115853 complement(2169116..2170672) 1 NC_011757.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: mpo:Mpop_1236 glucose-methanol-choline oxidoreductase; glucose-methanol-choline oxidoreductase 2170672 7115853 Mchl_2069 Methylobacterium extorquens CM4 glucose-methanol-choline oxidoreductase YP_002420844.1 2169116 R 440085 CDS YP_002420845.1 218530029 7115854 complement(2170779..2171420) 1 NC_011757.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mpo:Mpop_1237 thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate TPP binding domain-containing protein 2171420 7115854 Mchl_2070 Methylobacterium extorquens CM4 thiamine pyrophosphate TPP binding domain-containing protein YP_002420845.1 2170779 R 440085 CDS YP_002420846.1 218530030 7115855 complement(2171417..2171917) 1 NC_011757.1 KEGG: mpo:Mpop_1238 sulfopyruvate decarboxylase; sulfopyruvate decarboxylase 2171917 7115855 Mchl_2071 Methylobacterium extorquens CM4 sulfopyruvate decarboxylase YP_002420846.1 2171417 R 440085 CDS YP_002420847.1 218530031 7115856 complement(2172027..2172944) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mpo:Mpop_1239 LysR family transcriptional regulator; LysR family transcriptional regulator 2172944 7115856 Mchl_2072 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002420847.1 2172027 R 440085 CDS YP_002420848.1 218530032 7115857 complement(2172963..2173604) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mpo:Mpop_1240 glutathione S-transferase domain; glutathione S-transferase domain-containing protein 2173604 7115857 Mchl_2073 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002420848.1 2172963 R 440085 CDS YP_002420849.1 218530033 7115858 complement(2173601..2174254) 1 NC_011757.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mpo:Mpop_1241 Rieske (2Fe-2S) domain protein; Rieske (2Fe-2S) domain-containing protein 2174254 7115858 Mchl_2074 Methylobacterium extorquens CM4 Rieske (2Fe-2S) domain-containing protein YP_002420849.1 2173601 R 440085 CDS YP_002420850.1 218530034 7115859 complement(2174247..2174528) 1 NC_011757.1 KEGG: mpo:Mpop_1242 hypothetical protein; hypothetical protein 2174528 7115859 Mchl_2075 Methylobacterium extorquens CM4 hypothetical protein YP_002420850.1 2174247 R 440085 CDS YP_002420851.1 218530035 7115860 2174889..2176004 1 NC_011757.1 PFAM: basic membrane lipoprotein; KEGG: mpo:Mpop_1243 basic membrane lipoprotein; basic membrane lipoprotein 2176004 7115860 Mchl_2076 Methylobacterium extorquens CM4 basic membrane lipoprotein YP_002420851.1 2174889 D 440085 CDS YP_002420852.1 218530036 7115861 2176004..2177593 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mpo:Mpop_1244 ABC transporter; ABC transporter 2177593 7115861 Mchl_2077 Methylobacterium extorquens CM4 ABC transporter YP_002420852.1 2176004 D 440085 CDS YP_002420853.1 218530037 7115862 2177590..2178642 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mpo:Mpop_1245 inner-membrane translocator; inner-membrane translocator 2178642 7115862 Mchl_2078 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420853.1 2177590 D 440085 CDS YP_002420854.1 218530038 7115863 2178669..2179604 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mpo:Mpop_1246 inner-membrane translocator; inner-membrane translocator 2179604 7115863 Mchl_2079 Methylobacterium extorquens CM4 inner-membrane translocator YP_002420854.1 2178669 D 440085 CDS YP_002420855.1 218530039 7115864 2179619..2181013 1 NC_011757.1 PFAM: amidohydrolase; amidohydrolase; KEGG: mpo:Mpop_1247 amidohydrolase; amidohydrolase 2181013 7115864 Mchl_2080 Methylobacterium extorquens CM4 amidohydrolase YP_002420855.1 2179619 D 440085 CDS YP_002420856.1 218530040 7115865 2181059..2181895 1 NC_011757.1 KEGG: mpo:Mpop_1248 hypothetical protein; hypothetical protein 2181895 7115865 Mchl_2081 Methylobacterium extorquens CM4 hypothetical protein YP_002420856.1 2181059 D 440085 CDS YP_002420857.1 218530041 7115866 2182377..2183369 1 NC_011757.1 PFAM: protein of unknown function DUF808; KEGG: mex:Mext_1746 hypothetical protein; hypothetical protein 2183369 7115866 Mchl_2082 Methylobacterium extorquens CM4 hypothetical protein YP_002420857.1 2182377 D 440085 CDS YP_002420858.1 218530042 7115867 2183618..2184748 1 NC_011757.1 PFAM: EAL domain protein; KEGG: mex:Mext_1747 EAL domain-containing protein; diguanylate phosphodiesterase 2184748 7115867 Mchl_2083 Methylobacterium extorquens CM4 diguanylate phosphodiesterase YP_002420858.1 2183618 D 440085 CDS YP_002420859.1 218530043 7115868 2184764..2186017 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_1748 diguanylate cyclase; diguanylate cyclase 2186017 7115868 Mchl_2084 Methylobacterium extorquens CM4 diguanylate cyclase YP_002420859.1 2184764 D 440085 CDS YP_002420860.1 218530044 7115869 2186244..2186924 1 NC_011757.1 PFAM: OmpW family protein; KEGG: mex:Mext_1749 OmpW family protein; OmpW family protein 2186924 7115869 Mchl_2085 Methylobacterium extorquens CM4 OmpW family protein YP_002420860.1 2186244 D 440085 CDS YP_002420861.1 218530045 7115870 complement(2187202..2187564) 1 NC_011757.1 KEGG: mex:Mext_1750 hypothetical protein; hypothetical protein 2187564 7115870 Mchl_2086 Methylobacterium extorquens CM4 hypothetical protein YP_002420861.1 2187202 R 440085 CDS YP_002420862.1 218530046 7115871 2187706..2187897 1 NC_011757.1 KEGG: mex:Mext_1751 hypothetical protein; hypothetical protein 2187897 7115871 Mchl_2087 Methylobacterium extorquens CM4 hypothetical protein YP_002420862.1 2187706 D 440085 CDS YP_002420863.1 218530047 7115872 2188308..2188604 1 NC_011757.1 KEGG: mex:Mext_1752 hypothetical protein; hypothetical protein 2188604 7115872 Mchl_2088 Methylobacterium extorquens CM4 hypothetical protein YP_002420863.1 2188308 D 440085 CDS YP_002420864.1 218530048 7115873 2188855..2189136 1 NC_011757.1 KEGG: mex:Mext_1753 hypothetical protein; hypothetical protein 2189136 7115873 Mchl_2089 Methylobacterium extorquens CM4 hypothetical protein YP_002420864.1 2188855 D 440085 CDS YP_002420865.1 218530049 7115874 2189281..2191101 1 NC_011757.1 KEGG: mex:Mext_1754 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; gamma-glutamyltransferase 2191101 7115874 Mchl_2090 Methylobacterium extorquens CM4 gamma-glutamyltransferase YP_002420865.1 2189281 D 440085 CDS YP_002420866.1 218530050 7115875 complement(2191098..2192024) 1 NC_011757.1 PFAM: aminoglycoside phosphotransferase; KEGG: mex:Mext_1755 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 2192024 7115875 Mchl_2091 Methylobacterium extorquens CM4 aminoglycoside phosphotransferase YP_002420866.1 2191098 R 440085 CDS YP_002420867.1 218530051 7115876 2192455..2193246 1 NC_011757.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: mex:Mext_1756 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 2193246 7115876 Mchl_2092 Methylobacterium extorquens CM4 phospholipid/glycerol acyltransferase YP_002420867.1 2192455 D 440085 CDS YP_002420868.1 218530052 7115877 2193336..2193620 1 NC_011757.1 PFAM: protein of unknown function DUF497; KEGG: mex:Mext_1757 hypothetical protein; hypothetical protein 2193620 7115877 Mchl_2093 Methylobacterium extorquens CM4 hypothetical protein YP_002420868.1 2193336 D 440085 CDS YP_002420869.1 218530053 7115878 2193574..2193903 1 NC_011757.1 KEGG: mex:Mext_1758 hypothetical protein; hypothetical protein 2193903 7115878 Mchl_2094 Methylobacterium extorquens CM4 hypothetical protein YP_002420869.1 2193574 D 440085 CDS YP_002420870.1 218530054 7115879 complement(2193961..2194650) 1 NC_011757.1 TIGRFAM: methionine biosynthesis protein MetW; PFAM: methionine biosynthesis MetW protein; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_1759 methionine biosynthesis protein MetW; methionine biosynthesis protein MetW 2194650 7115879 Mchl_2095 Methylobacterium extorquens CM4 methionine biosynthesis protein MetW YP_002420870.1 2193961 R 440085 CDS YP_002420871.1 218530055 7115880 complement(2194657..2195874) 1 NC_011757.1 KEGG: mex:Mext_1760 homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; homoserine O-acetyltransferase 2195874 7115880 Mchl_2096 Methylobacterium extorquens CM4 homoserine O-acetyltransferase YP_002420871.1 2194657 R 440085 CDS YP_002420872.1 218530056 7115881 2196279..2196782 1 NC_011757.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: methionine sulfoxide reductase B; KEGG: mex:Mext_1761 methionine-R-sulfoxide reductase; methionine-R-sulfoxide reductase 2196782 7115881 Mchl_2097 Methylobacterium extorquens CM4 methionine-R-sulfoxide reductase YP_002420872.1 2196279 D 440085 CDS YP_002420873.1 218530057 7115882 2196874..2197596 1 NC_011757.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; KEGG: mex:Mext_1762 peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 2197596 7115882 Mchl_2098 Methylobacterium extorquens CM4 peptide methionine sulfoxide reductase YP_002420873.1 2196874 D 440085 CDS YP_002420874.1 218530058 7115883 complement(2197642..2198139) 1 NC_011757.1 TIGRFAM: bacterioferritin; PFAM: rubrerythrin; Ferritin Dps family protein; KEGG: mex:Mext_1763 bacterioferritin; bacterioferritin 2198139 7115883 Mchl_2099 Methylobacterium extorquens CM4 bacterioferritin YP_002420874.1 2197642 R 440085 CDS YP_002420875.1 218530059 7115884 complement(2198180..2198470) 1 NC_011757.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: mex:Mext_1764 hypothetical protein; BFD domain-containing protein (2Fe-2S)-binding domain-containing protein 2198470 7115884 Mchl_2100 Methylobacterium extorquens CM4 BFD domain-containing protein (2Fe-2S)-binding domain-containing protein YP_002420875.1 2198180 R 440085 CDS YP_002420876.1 218530060 7115885 complement(2198812..2199675) 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_1765 UspA domain-containing protein; UspA domain-containing protein 2199675 7115885 Mchl_2101 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002420876.1 2198812 R 440085 CDS YP_002420877.1 218530061 7115886 complement(2199789..2200937) 1 NC_011757.1 PFAM: acyltransferase 3; KEGG: mex:Mext_1766 acyltransferase 3; acyltransferase 3 2200937 7115886 Mchl_2102 Methylobacterium extorquens CM4 acyltransferase 3 YP_002420877.1 2199789 R 440085 CDS YP_002420878.1 218530062 7115887 2201060..2201770 1 NC_011757.1 KEGG: mex:Mext_1767 hypothetical protein; hypothetical protein 2201770 7115887 Mchl_2103 Methylobacterium extorquens CM4 hypothetical protein YP_002420878.1 2201060 D 440085 CDS YP_002420879.1 218530063 7115888 complement(2202031..2203173) 1 NC_011757.1 PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mex:Mext_1768 radical SAM domain-containing protein; radical SAM protein 2203173 7115888 Mchl_2104 Methylobacterium extorquens CM4 radical SAM protein YP_002420879.1 2202031 R 440085 CDS YP_002420880.1 218530064 7115889 2203335..2203856 1 NC_011757.1 KEGG: mex:Mext_1769 hypothetical protein; hypothetical protein 2203856 7115889 Mchl_2105 Methylobacterium extorquens CM4 hypothetical protein YP_002420880.1 2203335 D 440085 CDS YP_002420881.1 218530065 7115890 complement(2203931..2204113) 1 NC_011757.1 KEGG: mex:Mext_1770 hypothetical protein; hypothetical protein 2204113 7115890 Mchl_2106 Methylobacterium extorquens CM4 hypothetical protein YP_002420881.1 2203931 R 440085 CDS YP_002420882.1 218530066 7115891 complement(2204356..2204523) 1 NC_011757.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2204523 rpmG 7115891 rpmG Methylobacterium extorquens CM4 50S ribosomal protein L33 YP_002420882.1 2204356 R 440085 CDS YP_002420883.1 218530067 7115892 complement(2204677..2205501) 1 NC_011757.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2205501 panB 7115892 panB Methylobacterium extorquens CM4 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002420883.1 2204677 R 440085 CDS YP_002420884.1 218530068 7115893 complement(2205928..2206323) 1 NC_011757.1 PFAM: thioredoxin domain; KEGG: mex:Mext_1773 thioredoxin domain-containing protein; thioredoxin domain 2206323 7115893 Mchl_2109 Methylobacterium extorquens CM4 thioredoxin domain YP_002420884.1 2205928 R 440085 CDS YP_002420885.1 218530069 7115894 complement(2206354..2206941) 1 NC_011757.1 KEGG: mex:Mext_1774 rhodanese; rhodanese 2206941 7115894 Mchl_2110 Methylobacterium extorquens CM4 rhodanese YP_002420885.1 2206354 R 440085 CDS YP_002420886.1 218530070 7115895 complement(2206959..2207774) 1 NC_011757.1 PFAM: Sulphur oxidation protein SoxZ; KEGG: mex:Mext_1775 sulphur oxidation protein SoxZ; sulfur oxidation protein SoxZ 2207774 7115895 Mchl_2111 Methylobacterium extorquens CM4 sulfur oxidation protein SoxZ YP_002420886.1 2206959 R 440085 CDS YP_002420887.1 218530071 7115896 complement(2207816..2208748) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_1776 beta-lactamase domain-containing protein; beta-lactamase 2208748 7115896 Mchl_2112 Methylobacterium extorquens CM4 beta-lactamase YP_002420887.1 2207816 R 440085 CDS YP_002420888.1 218530072 7115897 2208934..2209518 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_1777 regulatory protein TetR; TetR family transcriptional regulator 2209518 7115897 Mchl_2113 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002420888.1 2208934 D 440085 CDS YP_002420889.1 218530073 7115898 2209618..2210604 1 NC_011757.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: mex:Mext_1778 cobalamin synthesis protein P47K; cobalamin synthesis protein P47K 2210604 7115898 Mchl_2114 Methylobacterium extorquens CM4 cobalamin synthesis protein P47K YP_002420889.1 2209618 D 440085 CDS YP_002420890.1 218530074 7115899 complement(2210832..2210933) 1 NC_011757.1 hypothetical protein 2210933 7115899 Mchl_2115 Methylobacterium extorquens CM4 hypothetical protein YP_002420890.1 2210832 R 440085 CDS YP_002420891.1 218530075 7115900 complement(2211057..2211308) 1 NC_011757.1 KEGG: mex:Mext_1780 hypothetical protein; hypothetical protein 2211308 7115900 Mchl_2116 Methylobacterium extorquens CM4 hypothetical protein YP_002420891.1 2211057 R 440085 CDS YP_002420892.1 218530076 7115901 2211886..2213322 1 NC_011757.1 KEGG: mex:Mext_1781 hypothetical protein; hypothetical protein 2213322 7115901 Mchl_2117 Methylobacterium extorquens CM4 hypothetical protein YP_002420892.1 2211886 D 440085 CDS YP_002420893.1 218530077 7115902 2213319..2216696 1 NC_011757.1 KEGG: mex:Mext_1782 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; multi-sensor hybrid histidine kinase 2216696 7115902 Mchl_2118 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002420893.1 2213319 D 440085 CDS YP_002420894.1 218530078 7115903 2216797..2218245 1 NC_011757.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: mex:Mext_1783 protein of unknown function DUF463 YcjX family protein; hypothetical protein 2218245 7115903 Mchl_2119 Methylobacterium extorquens CM4 hypothetical protein YP_002420894.1 2216797 D 440085 CDS YP_002420895.1 218530079 7115904 2218242..2219264 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1784 hypothetical protein; hypothetical protein 2219264 7115904 Mchl_2120 Methylobacterium extorquens CM4 hypothetical protein YP_002420895.1 2218242 D 440085 CDS YP_002420896.1 218530080 7115905 complement(2219383..2219769) 1 NC_011757.1 KEGG: mex:Mext_1785 hypothetical protein; hypothetical protein 2219769 7115905 Mchl_2121 Methylobacterium extorquens CM4 hypothetical protein YP_002420896.1 2219383 R 440085 CDS YP_002420897.1 218530081 7115906 complement(2219978..2220529) 1 NC_011757.1 PFAM: protein of unknown function DUF1234; KEGG: mex:Mext_1786 hypothetical protein; hypothetical protein 2220529 7115906 Mchl_2122 Methylobacterium extorquens CM4 hypothetical protein YP_002420897.1 2219978 R 440085 CDS YP_002420898.1 218530082 7115907 complement(2220600..2221868) 1 NC_011757.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mex:Mext_1787 diaminopimelate decarboxylase; diaminopimelate decarboxylase 2221868 7115907 Mchl_2123 Methylobacterium extorquens CM4 diaminopimelate decarboxylase YP_002420898.1 2220600 R 440085 CDS YP_002420899.1 218530083 7115908 complement(2222068..2222418) 1 NC_011757.1 KEGG: mex:Mext_1788 hypothetical protein; hypothetical protein 2222418 7115908 Mchl_2124 Methylobacterium extorquens CM4 hypothetical protein YP_002420899.1 2222068 R 440085 CDS YP_002420900.1 218530084 7115909 complement(2222571..2222849) 1 NC_011757.1 KEGG: mex:Mext_1789 hypothetical protein; hypothetical protein 2222849 7115909 Mchl_2125 Methylobacterium extorquens CM4 hypothetical protein YP_002420900.1 2222571 R 440085 CDS YP_002420901.1 218530085 7115910 complement(2223040..2223762) 1 NC_011757.1 KEGG: mex:Mext_1790 hypothetical protein; hypothetical protein 2223762 7115910 Mchl_2126 Methylobacterium extorquens CM4 hypothetical protein YP_002420901.1 2223040 R 440085 CDS YP_002420902.1 218530086 7115911 complement(2223987..2224604) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1791 hypothetical protein; hypothetical protein 2224604 7115911 Mchl_2127 Methylobacterium extorquens CM4 hypothetical protein YP_002420902.1 2223987 R 440085 CDS YP_002420903.1 218530087 7115912 complement(2224959..2225609) 1 NC_011757.1 PFAM: ribonuclease HII/HIII; KEGG: mex:Mext_1792 ribonuclease H; ribonuclease H 2225609 7115912 Mchl_2128 Methylobacterium extorquens CM4 ribonuclease H YP_002420903.1 2224959 R 440085 CDS YP_002420904.1 218530088 7115913 complement(2225737..2226813) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1793 glycosyl transferase group 1; group 1 glycosyl transferase 2226813 7115913 Mchl_2129 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002420904.1 2225737 R 440085 CDS YP_002420905.1 218530089 7115914 complement(2226934..2227746) 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_1794 metallophosphoesterase; metallophosphoesterase 2227746 7115914 Mchl_2130 Methylobacterium extorquens CM4 metallophosphoesterase YP_002420905.1 2226934 R 440085 CDS YP_002420906.1 218530090 7115915 2228409..2229617 1 NC_011757.1 PFAM: aminotransferase class V; KEGG: mex:Mext_1795 serine--glyoxylate transaminase; class V aminotransferase 2229617 7115915 Mchl_2131 Methylobacterium extorquens CM4 class V aminotransferase YP_002420906.1 2228409 D 440085 CDS YP_002420907.1 218530091 7115916 2229898..2230842 1 NC_011757.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_1796 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 2230842 7115916 Mchl_2132 Methylobacterium extorquens CM4 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_002420907.1 2229898 D 440085 CDS YP_002420908.1 218530092 7115917 2230986..2231852 1 NC_011757.1 PFAM: methylene-tetrahydromethanopterin dehydrogenase; KEGG: mex:Mext_1797 methylenetetrahydrofolate dehydrogenase (NADP(+)); methylenetetrahydrofolate dehydrogenase (NADP(+)) 2231852 7115917 Mchl_2133 Methylobacterium extorquens CM4 methylenetetrahydrofolate dehydrogenase (NADP(+)) YP_002420908.1 2230986 D 440085 CDS YP_002420909.1 218530093 7115918 2231946..2232572 1 NC_011757.1 PFAM: formiminotransferase-cyclodeaminase; KEGG: mex:Mext_1798 formiminotransferase-cyclodeaminase; formiminotransferase-cyclodeaminase 2232572 7115918 Mchl_2134 Methylobacterium extorquens CM4 formiminotransferase-cyclodeaminase YP_002420909.1 2231946 D 440085 CDS YP_002420910.1 218530094 7115919 2233122..2234294 1 NC_011757.1 catalyzes the formation of malyl-CoA from malate and CoA; malate--CoA ligase subunit beta 2234294 7115919 Mchl_2135 Methylobacterium extorquens CM4 malate--CoA ligase subunit beta YP_002420910.1 2233122 D 440085 CDS YP_002420911.1 218530095 7115920 2234317..2235207 1 NC_011757.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 2235207 7115920 Mchl_2136 Methylobacterium extorquens CM4 succinyl-CoA synthetase subunit alpha YP_002420911.1 2234317 D 440085 CDS YP_002420912.1 218530096 7115921 2235492..2238260 1 NC_011757.1 PFAM: phosphoenolpyruvate carboxylase; KEGG: mex:Mext_1801 phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 2238260 7115921 Mchl_2137 Methylobacterium extorquens CM4 phosphoenolpyruvate carboxylase YP_002420912.1 2235492 D 440085 CDS YP_002420913.1 218530097 7115922 2238448..2239422 1 NC_011757.1 PFAM: HpcH/HpaI aldolase; KEGG: mex:Mext_1802 citrate (pro-3S)-lyase; citrate (pro-3S)-lyase 2239422 7115922 Mchl_2138 Methylobacterium extorquens CM4 citrate (pro-3S)-lyase YP_002420913.1 2238448 D 440085 CDS YP_002420914.1 218530098 7115923 complement(2239493..2240059) 1 NC_011757.1 PFAM: protein of unknown function DUF1003; KEGG: mex:Mext_1803 hypothetical protein; hypothetical protein 2240059 7115923 Mchl_2139 Methylobacterium extorquens CM4 hypothetical protein YP_002420914.1 2239493 R 440085 CDS YP_002420915.1 218530099 7116005 2240355..2241230 1 NC_011757.1 PFAM: dienelactone hydrolase; KEGG: mex:Mext_1804 carboxymethylenebutenolidase; carboxymethylenebutenolidase 2241230 7116005 Mchl_2140 Methylobacterium extorquens CM4 carboxymethylenebutenolidase YP_002420915.1 2240355 D 440085 CDS YP_002420916.1 218530100 7116087 complement(2241238..2241615) 1 NC_011757.1 PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mpo:Mpop_1757 transcriptional coactivator/pterin dehydratase; transcriptional coactivator/pterin dehydratase 2241615 7116087 Mchl_2141 Methylobacterium extorquens CM4 transcriptional coactivator/pterin dehydratase YP_002420916.1 2241238 R 440085 CDS YP_002420917.1 218530101 7116088 2241842..2242837 1 NC_011757.1 KEGG: mex:Mext_1806 ABC transporter periplasmic solute-binding protein; ABC transporter periplasmic protein 2242837 7116088 Mchl_2142 Methylobacterium extorquens CM4 ABC transporter periplasmic protein YP_002420917.1 2241842 D 440085 CDS YP_002420918.1 218530102 7116089 2242877..2243611 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_1807 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 2243611 7116089 Mchl_2143 Methylobacterium extorquens CM4 ABC transporter inner membrane protein YP_002420918.1 2242877 D 440085 CDS YP_002420919.1 218530103 7116090 2243592..2244365 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1808 ABC transporter; ABC transporter 2244365 7116090 Mchl_2144 Methylobacterium extorquens CM4 ABC transporter YP_002420919.1 2243592 D 440085 CDS YP_002420920.1 218530104 7116091 2245072..2246877 1 NC_011757.1 TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: pyrrolo-quinoline quinone; KEGG: mex:Mext_1809 methanol/ethanol family PQQ-dependent dehydrogenase; methanol/ethanol family PQQ-dependent dehydrogenase 2246877 7116091 Mchl_2145 Methylobacterium extorquens CM4 methanol/ethanol family PQQ-dependent dehydrogenase YP_002420920.1 2245072 D 440085 CDS YP_002420921.1 218530105 7116092 2247023..2247622 1 NC_011757.1 KEGG: mex:Mext_1810 hypothetical protein; hypothetical protein 2247622 7116092 Mchl_2146 Methylobacterium extorquens CM4 hypothetical protein YP_002420921.1 2247023 D 440085 CDS YP_002420922.1 218530106 7116093 2247622..2248476 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_1811 extracellular solute-binding protein; family 3 extracellular solute-binding protein 2248476 7116093 Mchl_2147 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002420922.1 2247622 D 440085 CDS YP_002420923.1 218530107 7116094 complement(2248582..2249058) 1 NC_011757.1 KEGG: mex:Mext_1812 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 2249058 7116094 Mchl_2148 Methylobacterium extorquens CM4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002420923.1 2248582 R 440085 CDS YP_002420924.1 218530108 7116095 complement(2249055..2249447) 1 NC_011757.1 TIGRFAM: dihydroneopterin aldolase; KEGG: mex:Mext_1813 dihydroneopterin aldolase; dihydroneopterin aldolase 2249447 7116095 Mchl_2149 Methylobacterium extorquens CM4 dihydroneopterin aldolase YP_002420924.1 2249055 R 440085 CDS YP_002420925.1 218530109 7116096 complement(2249440..2250309) 1 NC_011757.1 KEGG: mex:Mext_1814 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; dihydropteroate synthase 2250309 7116096 Mchl_2150 Methylobacterium extorquens CM4 dihydropteroate synthase YP_002420925.1 2249440 R 440085 CDS YP_002420926.1 218530110 7116097 complement(2250404..2250769) 1 NC_011757.1 KEGG: mpo:Mpop_1767 hypothetical protein; hypothetical protein 2250769 7116097 Mchl_2151 Methylobacterium extorquens CM4 hypothetical protein YP_002420926.1 2250404 R 440085 CDS YP_002420927.1 218530111 7116098 complement(2250750..2251484) 1 NC_011757.1 KEGG: mex:Mext_1816 hypothetical protein; hypothetical protein 2251484 7116098 Mchl_2152 Methylobacterium extorquens CM4 hypothetical protein YP_002420927.1 2250750 R 440085 CDS YP_002420928.1 218530112 7116099 complement(2251481..2252635) 1 NC_011757.1 TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: radical SAM protein; KEGG: mex:Mext_1817 pyrroloquinoline quinone biosynthesis protein PqqE; pyrroloquinoline quinone biosynthesis protein PqqE 2252635 7116099 Mchl_2153 Methylobacterium extorquens CM4 pyrroloquinoline quinone biosynthesis protein PqqE YP_002420928.1 2251481 R 440085 CDS YP_002420929.1 218530113 7116100 complement(2252632..2253750) 1 NC_011757.1 Required in the synthesis of PPQ, but its exact function is unknown; pyrroloquinoline quinone biosynthesis protein PqqC 2253750 7116100 Mchl_2154 Methylobacterium extorquens CM4 pyrroloquinoline quinone biosynthesis protein PqqC YP_002420929.1 2252632 R 440085 CDS YP_002420930.1 218530114 7116101 complement(2253917..2254816) 1 NC_011757.1 possibly involved in transport of pyrroloquinoline quinone transport; pyrroloquinoline quinone biosynthesis protein PqqB 2254816 7116101 Mchl_2155 Methylobacterium extorquens CM4 pyrroloquinoline quinone biosynthesis protein PqqB YP_002420930.1 2253917 R 440085 CDS YP_002420931.1 218530115 7116102 complement(2255289..2255996) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_1821 response regulator receiver; transcriptional regulator 2255996 7116102 Mchl_2156 Methylobacterium extorquens CM4 transcriptional regulator YP_002420931.1 2255289 R 440085 CDS YP_002420932.1 218530116 7116103 complement(2255993..2257630) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_1822 ATPase domain-containing protein; histidine kinase 2257630 7116103 Mchl_2157 Methylobacterium extorquens CM4 histidine kinase YP_002420932.1 2255993 R 440085 CDS YP_002420933.1 218530117 7116104 complement(2257739..2257945) 1 NC_011757.1 KEGG: mex:Mext_1823 hypothetical protein; hypothetical protein 2257945 7116104 Mchl_2158 Methylobacterium extorquens CM4 hypothetical protein YP_002420933.1 2257739 R 440085 CDS YP_002420934.1 218530118 7116105 complement(2258093..2258890) 1 NC_011757.1 TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase subunit alpha domain protein; KEGG: mex:Mext_1824 formylmethanofuran dehydrogenase subunit C; formylmethanofuran dehydrogenase subunit C 2258890 7116105 Mchl_2159 Methylobacterium extorquens CM4 formylmethanofuran dehydrogenase subunit C YP_002420934.1 2258093 R 440085 CDS YP_002420935.1 218530119 7116106 complement(2258887..2259822) 1 NC_011757.1 catalyzes the transfer of a formyl group from formylmethanofuran to tetrahydromethanopterin tetrahydromethanopterin; formylmethanofuran--tetrahydromethanopterin formyltransferase 2259822 7116106 Mchl_2160 Methylobacterium extorquens CM4 formylmethanofuran--tetrahydromethanopterin formyltransferase YP_002420935.1 2258887 R 440085 CDS YP_002420936.1 218530120 7116107 complement(2259848..2261494) 1 NC_011757.1 TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: amidohydrolase; KEGG: mex:Mext_1826 formylmethanofuran dehydrogenase subunit A; formylmethanofuran dehydrogenase subunit A 2261494 7116107 Mchl_2161 Methylobacterium extorquens CM4 formylmethanofuran dehydrogenase subunit A YP_002420936.1 2259848 R 440085 CDS YP_002420937.1 218530121 7116108 complement(2261488..2262576) 1 NC_011757.1 KEGG: mex:Mext_1827 tungsten-containing formylmethanofuran dehydrogenase, subunit B; tungsten-containing formylmethanofuran dehydrogenase subunit B 2262576 7116108 Mchl_2162 Methylobacterium extorquens CM4 tungsten-containing formylmethanofuran dehydrogenase subunit B YP_002420937.1 2261488 R 440085 CDS YP_002420938.1 218530122 7116109 2262981..2264003 1 NC_011757.1 TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: mex:Mext_1828 beta-ribofuranosylaminobenzene 5'-phosphate synthase; beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2264003 7116109 Mchl_2163 Methylobacterium extorquens CM4 beta-ribofuranosylaminobenzene 5'-phosphate synthase family YP_002420938.1 2262981 D 440085 CDS YP_002420939.1 218530123 7116110 2264114..2265007 1 NC_011757.1 PFAM: methylene-tetrahydromethanopterin dehydrogenase; KEGG: mex:Mext_1829 methylene-tetrahydromethanopterin dehydrogenase; methylene-tetrahydromethanopterin dehydrogenase 2265007 7116110 Mchl_2164 Methylobacterium extorquens CM4 methylene-tetrahydromethanopterin dehydrogenase YP_002420939.1 2264114 D 440085 CDS YP_002420940.1 218530124 7116111 2265004..2266242 1 NC_011757.1 PFAM: protein of unknown function DUF201; KEGG: mex:Mext_1830 hypothetical protein; hypothetical protein 2266242 7116111 Mchl_2165 Methylobacterium extorquens CM4 hypothetical protein YP_002420940.1 2265004 D 440085 CDS YP_002420941.1 218530125 7116112 2266172..2267143 1 NC_011757.1 catalyzes the reversible formation of methenyl-H(4)methanopterin from N(5)-formyl-H(4)methanopterin; N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase 2267143 7116112 Mchl_2166 Methylobacterium extorquens CM4 N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase YP_002420941.1 2266172 D 440085 CDS YP_002420942.1 218530126 7116113 2267421..2268335 1 NC_011757.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mex:Mext_1832 alpha-L-glutamate ligase; alpha-L-glutamate ligase, RimK family 2268335 7116113 Mchl_2167 Methylobacterium extorquens CM4 alpha-L-glutamate ligase, RimK family YP_002420942.1 2267421 D 440085 CDS YP_002420943.1 218530127 7116114 2268332..2269201 1 NC_011757.1 PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mex:Mext_1833 triphosphoribosyl-dephospho-CoA protein; triphosphoribosyl-dephospho-CoA protein 2269201 7116114 Mchl_2168 Methylobacterium extorquens CM4 triphosphoribosyl-dephospho-CoA protein YP_002420943.1 2268332 D 440085 CDS YP_002420944.1 218530128 7116115 2269459..2269971 1 NC_011757.1 TIGRFAM: formaldehyde-activating enzyme; PFAM: formaldehyde-activating enzyme (Fae); KEGG: mex:Mext_1834 formaldehyde-activating enzyme; formaldehyde-activating enzyme 2269971 7116115 Mchl_2169 Methylobacterium extorquens CM4 formaldehyde-activating enzyme YP_002420944.1 2269459 D 440085 CDS YP_002420945.1 218530129 7116116 complement(2270111..2270806) 1 NC_011757.1 PFAM: histidine biosynthesis protein; KEGG: mex:Mext_1835 histidine biosynthesis protein; histidine biosynthesis protein 2270806 7116116 Mchl_2170 Methylobacterium extorquens CM4 histidine biosynthesis protein YP_002420945.1 2270111 R 440085 CDS YP_002420946.1 218530130 7116117 2270810..2271844 1 NC_011757.1 TIGRFAM: H4MPT-linked C1 transfer pathway protein; PFAM: hydantoinase/oxoprolinase; KEGG: mex:Mext_1836 H4MPT-linked C1 transfer pathway protein; H4MPT-linked C1 transfer pathway protein 2271844 7116117 Mchl_2171 Methylobacterium extorquens CM4 H4MPT-linked C1 transfer pathway protein YP_002420946.1 2270810 D 440085 CDS YP_002420947.1 218530131 7116118 2271897..2272097 1 NC_011757.1 KEGG: mex:Mext_1837 hypothetical protein; hypothetical protein 2272097 7116118 Mchl_2172 Methylobacterium extorquens CM4 hypothetical protein YP_002420947.1 2271897 D 440085 CDS YP_002420948.1 218530132 7116119 complement(2272100..2273200) 1 NC_011757.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: mex:Mext_1838 YVTN beta-propeller repeat-containing protein; 40-residue YVTN family beta-propeller repeat-containing protein 2273200 7116119 Mchl_2173 Methylobacterium extorquens CM4 40-residue YVTN family beta-propeller repeat-containing protein YP_002420948.1 2272100 R 440085 CDS YP_002420949.1 218530133 7116120 complement(2273226..2273756) 1 NC_011757.1 KEGG: mex:Mext_1839 signal peptide; signal peptide 2273756 7116120 Mchl_2174 Methylobacterium extorquens CM4 signal peptide YP_002420949.1 2273226 R 440085 CDS YP_002420950.1 218530134 7116121 complement(2273823..2274356) 1 NC_011757.1 KEGG: mex:Mext_1840 hypothetical protein; hypothetical protein 2274356 7116121 Mchl_2175 Methylobacterium extorquens CM4 hypothetical protein YP_002420950.1 2273823 R 440085 CDS YP_002420951.1 218530135 7116122 complement(2274398..2274994) 1 NC_011757.1 PFAM: protein of unknown function DUF447; KEGG: mex:Mext_1841 hypothetical protein; hypothetical protein 2274994 7116122 Mchl_2176 Methylobacterium extorquens CM4 hypothetical protein YP_002420951.1 2274398 R 440085 CDS YP_002420952.1 218530136 7116123 complement(2275052..2276626) 1 NC_011757.1 PFAM: dihydropteroate synthase DHPS; KEGG: mex:Mext_1842 dihydropteroate synthase DhpS; dihydropteroate synthase DHPS 2276626 7116123 Mchl_2177 Methylobacterium extorquens CM4 dihydropteroate synthase DHPS YP_002420952.1 2275052 R 440085 CDS YP_002420953.1 218530137 7116124 complement(2276623..2277237) 1 NC_011757.1 PFAM: aspartate/glutamate/uridylate kinase; KEGG: mex:Mext_1843 aspartate/glutamate/uridylate kinase; aspartate/glutamate/uridylate kinase 2277237 7116124 Mchl_2178 Methylobacterium extorquens CM4 aspartate/glutamate/uridylate kinase YP_002420953.1 2276623 R 440085 CDS YP_002420954.1 218530138 7116125 complement(2277243..2277953) 1 NC_011757.1 PFAM: protein of unknown function DUF556; KEGG: mex:Mext_1844 hypothetical protein; hypothetical protein 2277953 7116125 Mchl_2179 Methylobacterium extorquens CM4 hypothetical protein YP_002420954.1 2277243 R 440085 CDS YP_002420955.1 218530139 7116126 complement(2277999..2278532) 1 NC_011757.1 KEGG: mex:Mext_1845 hypothetical protein; hypothetical protein 2278532 7116126 Mchl_2180 Methylobacterium extorquens CM4 hypothetical protein YP_002420955.1 2277999 R 440085 CDS YP_002420956.1 218530140 7116127 2278765..2280033 1 NC_011757.1 KEGG: mex:Mext_1846 hypothetical protein; hypothetical protein 2280033 7116127 Mchl_2181 Methylobacterium extorquens CM4 hypothetical protein YP_002420956.1 2278765 D 440085 CDS YP_002420957.1 218530141 7116128 2280200..2281186 1 NC_011757.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: mex:Mext_1847 YVTN beta-propeller repeat-containing protein; 40-residue YVTN family beta-propeller repeat-containing protein 2281186 7116128 Mchl_2182 Methylobacterium extorquens CM4 40-residue YVTN family beta-propeller repeat-containing protein YP_002420957.1 2280200 D 440085 CDS YP_002420958.1 218530142 7116129 2281279..2281713 1 NC_011757.1 KEGG: mex:Mext_1848 hypothetical protein; hypothetical protein 2281713 7116129 Mchl_2183 Methylobacterium extorquens CM4 hypothetical protein YP_002420958.1 2281279 D 440085 CDS YP_002420959.1 218530143 7116130 2281726..2282004 1 NC_011757.1 KEGG: mex:Mext_1849 hypothetical protein; hypothetical protein 2282004 7116130 Mchl_2184 Methylobacterium extorquens CM4 hypothetical protein YP_002420959.1 2281726 D 440085 CDS YP_002420960.1 218530144 7116131 2282001..2282750 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1850 ABC transporter; ABC transporter 2282750 7116131 Mchl_2185 Methylobacterium extorquens CM4 ABC transporter YP_002420960.1 2282001 D 440085 CDS YP_002420961.1 218530145 7116132 2282747..2283640 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_1851 ABC-2 type transporter; ABC transporter 2283640 7116132 Mchl_2186 Methylobacterium extorquens CM4 ABC transporter YP_002420961.1 2282747 D 440085 CDS YP_002420962.1 218530146 7116133 2283651..2284280 1 NC_011757.1 KEGG: mex:Mext_1852 hypothetical protein; hypothetical protein 2284280 7116133 Mchl_2187 Methylobacterium extorquens CM4 hypothetical protein YP_002420962.1 2283651 D 440085 CDS YP_002420963.1 218530147 7116134 2284817..2287342 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_1853 TonB-dependent receptor; TonB-dependent receptor 2287342 7116134 Mchl_2188 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002420963.1 2284817 D 440085 CDS YP_002420964.1 218530148 7116135 2287660..2288061 1 NC_011757.1 KEGG: mex:Mext_1854 hypothetical protein; signal transduction protein with EFhand domain 2288061 7116135 Mchl_2189 Methylobacterium extorquens CM4 signal transduction protein with EFhand domain YP_002420964.1 2287660 D 440085 CDS YP_002420965.1 218530149 7116136 2288264..2288623 1 NC_011757.1 KEGG: mex:Mext_1855 hypothetical protein; hypothetical protein 2288623 7116136 Mchl_2190 Methylobacterium extorquens CM4 hypothetical protein YP_002420965.1 2288264 D 440085 CDS YP_002420966.1 218530150 7116137 complement(2288727..2290283) 1 NC_011757.1 KEGG: mex:Mext_1856 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 2290283 7116137 Mchl_2191 Methylobacterium extorquens CM4 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_002420966.1 2288727 R 440085 CDS YP_002420967.1 218530151 7116138 complement(2290415..2291674) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1857 glycosyl transferase group 1; group 1 glycosyl transferase 2291674 7116138 Mchl_2192 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002420967.1 2290415 R 440085 CDS YP_002420968.1 218530152 7116139 complement(2291847..2292425) 1 NC_011757.1 PFAM: polysaccharide export protein; KEGG: mex:Mext_1858 polysaccharide export protein; polysaccharide export protein 2292425 7116139 Mchl_2193 Methylobacterium extorquens CM4 polysaccharide export protein YP_002420968.1 2291847 R 440085 CDS YP_002420969.1 218530153 7116140 2292647..2295061 1 NC_011757.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: mex:Mext_1859 lipopolysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 2295061 7116140 Mchl_2194 Methylobacterium extorquens CM4 lipopolysaccharide biosynthesis protein YP_002420969.1 2292647 D 440085 CDS YP_002420970.1 218530154 7116141 complement(2295616..2295939) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1860 hypothetical protein; hypothetical protein 2295939 7116141 Mchl_2195 Methylobacterium extorquens CM4 hypothetical protein YP_002420970.1 2295616 R 440085 CDS YP_002420971.1 218530155 7116142 complement(2296030..2297910) 1 NC_011757.1 KEGG: mex:Mext_1861 DNA polymerase III subunits gamma and tau; TIGRFAM: DNA polymerase III subunits gamma and tau; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; DNA polymerase III subunits gamma and tau 2297910 7116142 Mchl_2196 Methylobacterium extorquens CM4 DNA polymerase III subunits gamma and tau YP_002420971.1 2296030 R 440085 CDS YP_002420972.1 218530156 7116144 2298167..2298655 1 NC_011757.1 KEGG: mex:Mext_1862 hypothetical protein; hypothetical protein 2298655 7116144 Mchl_2197 Methylobacterium extorquens CM4 hypothetical protein YP_002420972.1 2298167 D 440085 CDS YP_002420973.1 218530157 7116145 complement(2298690..2298950) 1 NC_011757.1 KEGG: mex:Mext_1863 hypothetical protein; hypothetical protein 2298950 7116145 Mchl_2198 Methylobacterium extorquens CM4 hypothetical protein YP_002420973.1 2298690 R 440085 CDS YP_002420974.1 218530158 7116146 2299100..2300638 1 NC_011757.1 KEGG: mpo:Mpop_1815 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; Mg chelatase subunit ChlI 2300638 7116146 Mchl_2199 Methylobacterium extorquens CM4 Mg chelatase subunit ChlI YP_002420974.1 2299100 D 440085 CDS YP_002420975.1 218530159 7116147 2300937..2301545 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_1924 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 2301545 7116147 Mchl_2200 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002420975.1 2300937 D 440085 CDS YP_002420976.1 218530160 7116148 2301722..2302918 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_1925 hypothetical protein; hypothetical protein 2302918 7116148 Mchl_2201 Methylobacterium extorquens CM4 hypothetical protein YP_002420976.1 2301722 D 440085 CDS YP_002420977.1 218530161 7116149 2302950..2304293 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_1926 ATPase domain-containing protein; histidine kinase 2304293 7116149 Mchl_2202 Methylobacterium extorquens CM4 histidine kinase YP_002420977.1 2302950 D 440085 CDS YP_002420978.1 218530162 7116150 complement(2304316..2304639) 1 NC_011757.1 KEGG: mex:Mext_1927 hypothetical protein; hypothetical protein 2304639 7116150 Mchl_2203 Methylobacterium extorquens CM4 hypothetical protein YP_002420978.1 2304316 R 440085 CDS YP_002420979.1 218530163 7116151 complement(2304952..2305620) 1 NC_011757.1 PFAM: cysteine peptidase; KEGG: mex:Mext_1928 cysteine peptidase; cysteine peptidase 2305620 7116151 Mchl_2204 Methylobacterium extorquens CM4 cysteine peptidase YP_002420979.1 2304952 R 440085 CDS YP_002420980.1 218530164 7116152 2305864..2306283 1 NC_011757.1 PFAM: thioesterase superfamily protein; KEGG: mex:Mext_1929 thioesterase superfamily protein; thioesterase superfamily protein 2306283 7116152 Mchl_2205 Methylobacterium extorquens CM4 thioesterase superfamily protein YP_002420980.1 2305864 D 440085 CDS YP_002420981.1 218530165 7116153 complement(2306319..2307224) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: mex:Mext_1930 alpha/beta hydrolase domain-containing protein; alpha/beta hydrolase fold-3 domain-containing protein 2307224 7116153 Mchl_2206 Methylobacterium extorquens CM4 alpha/beta hydrolase fold-3 domain-containing protein YP_002420981.1 2306319 R 440085 CDS YP_002420982.1 218530166 7116154 complement(2307288..2308274) 1 NC_011757.1 PFAM: sporulation domain protein; lytic transglycosylase catalytic; KEGG: mex:Mext_1931 lytic transglycosylase catalytic; lytic transglycosylase 2308274 7116154 Mchl_2207 Methylobacterium extorquens CM4 lytic transglycosylase YP_002420982.1 2307288 R 440085 CDS YP_002420983.1 218530167 7116155 2308441..2310621 1 NC_011757.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mex:Mext_1932 molybdopterin oxidoreductase; molybdopterin oxidoreductase 2310621 7116155 Mchl_2208 Methylobacterium extorquens CM4 molybdopterin oxidoreductase YP_002420983.1 2308441 D 440085 CDS YP_002420984.1 218530168 7116156 2310728..2312356 1 NC_011757.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_1933 ABC transporter related; ABC transporter 2312356 7116156 Mchl_2209 Methylobacterium extorquens CM4 ABC transporter YP_002420984.1 2310728 D 440085 CDS YP_002420985.1 218530169 7116157 2312360..2313577 1 NC_011757.1 KEGG: mex:Mext_1934 phosphopentomutase; TIGRFAM: phosphopentomutase; PFAM: metalloenzyme domain protein; phosphopentomutase domain protein; phosphopentomutase 2313577 7116157 Mchl_2210 Methylobacterium extorquens CM4 phosphopentomutase YP_002420985.1 2312360 D 440085 CDS YP_002420986.1 218530170 7116158 complement(2313866..2315518) 1 NC_011757.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 2315518 7116158 Mchl_2211 Methylobacterium extorquens CM4 ABC transporter ATP-binding protein YP_002420986.1 2313866 R 440085 CDS YP_002420987.1 218530171 7116159 complement(2315754..2316032) 1 NC_011757.1 KEGG: mex:Mext_1936 hypothetical protein; hypothetical protein 2316032 7116159 Mchl_2212 Methylobacterium extorquens CM4 hypothetical protein YP_002420987.1 2315754 R 440085 CDS YP_002420988.1 218530172 7116160 complement(2316043..2316918) 1 NC_011757.1 PFAM: DNA/RNA non-specific endonuclease; KEGG: mex:Mext_1937 DNA/RNA non-specific endonuclease; DNA/RNA non-specific endonuclease 2316918 7116160 Mchl_2213 Methylobacterium extorquens CM4 DNA/RNA non-specific endonuclease YP_002420988.1 2316043 R 440085 CDS YP_002420989.1 218530173 7116161 complement(2316926..2317180) 1 NC_011757.1 KEGG: mex:Mext_1938 hypothetical protein; hypothetical protein 2317180 7116161 Mchl_2214 Methylobacterium extorquens CM4 hypothetical protein YP_002420989.1 2316926 R 440085 CDS YP_002420990.1 218530174 7116162 2317504..2319486 1 NC_011757.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2319486 7116162 Mchl_2215 Methylobacterium extorquens CM4 1-deoxy-D-xylulose-5-phosphate synthase YP_002420990.1 2317504 D 440085 CDS YP_002420991.1 218530175 7116163 2319695..2320720 1 NC_011757.1 TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_1940 hopanoid-associated sugar epimerase; hopanoid-associated sugar epimerase 2320720 7116163 Mchl_2216 Methylobacterium extorquens CM4 hopanoid-associated sugar epimerase YP_002420991.1 2319695 D 440085 CDS YP_002420992.1 218530176 7116164 2320717..2321616 1 NC_011757.1 TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: mex:Mext_1941 squalene synthase HpnC; squalene synthase HpnC 2321616 7116164 Mchl_2217 Methylobacterium extorquens CM4 squalene synthase HpnC YP_002420992.1 2320717 D 440085 CDS YP_002420993.1 218530177 7116165 2321613..2322464 1 NC_011757.1 TIGRFAM: squalene synthase HpnD; PFAM: Squalene/phytoene synthase; KEGG: mex:Mext_1942 squalene synthase HpnD; squalene synthase HpnD 2322464 7116165 Mchl_2218 Methylobacterium extorquens CM4 squalene synthase HpnD YP_002420993.1 2321613 D 440085 CDS YP_002420994.1 218530178 7116166 2322464..2323765 1 NC_011757.1 TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; KEGG: mex:Mext_1943 squalene-associated FAD-dependent desaturase; squalene-associated FAD-dependent desaturase 2323765 7116166 Mchl_2219 Methylobacterium extorquens CM4 squalene-associated FAD-dependent desaturase YP_002420994.1 2322464 D 440085 CDS YP_002420995.1 218530179 7116167 2323810..2325813 1 NC_011757.1 KEGG: mex:Mext_1944 squalene-hopene cyclase; TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: prenyltransferase/squalene oxidase; squalene-hopene cyclase 2325813 7116167 Mchl_2220 Methylobacterium extorquens CM4 squalene-hopene cyclase YP_002420995.1 2323810 D 440085 CDS YP_002420996.1 218530180 7114693 2325939..2326607 1 NC_011757.1 KEGG: mex:Mext_1945 hypothetical protein; hypothetical protein 2326607 7114693 Mchl_2221 Methylobacterium extorquens CM4 hypothetical protein YP_002420996.1 2325939 D 440085 CDS YP_002420997.1 218530181 7114778 complement(2326702..2328075) 1 NC_011757.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aminotransferase class I and II; aminotransferase class-III; KEGG: mex:Mext_1946 8-amino-7-oxononanoate synthase; 8-amino-7-oxononanoate synthase 2328075 7114778 Mchl_2222 Methylobacterium extorquens CM4 8-amino-7-oxononanoate synthase YP_002420997.1 2326702 R 440085 CDS YP_002420998.1 218530182 7114779 complement(2328072..2335478) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KR domain protein; beta-ketoacyl synthase ; acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase; beta-ketoacyl synthase 2335478 7114779 Mchl_2223 Methylobacterium extorquens CM4 beta-ketoacyl synthase YP_002420998.1 2328072 R 440085 CDS YP_002420999.1 218530183 7114780 complement(2335998..2337302) 1 NC_011757.1 KEGG: mex:Mext_1948 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; nucleotide sugar dehydrogenase 2337302 7114780 Mchl_2224 Methylobacterium extorquens CM4 nucleotide sugar dehydrogenase YP_002420999.1 2335998 R 440085 CDS YP_002421000.1 218530184 7114781 complement(2337402..2339555) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_1949 glycosyl transferase; family 2 glycosyl transferase 2339555 7114781 Mchl_2225 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002421000.1 2337402 R 440085 CDS YP_002421001.1 218530185 7114782 complement(2339562..2340608) 1 NC_011757.1 KEGG: mex:Mext_1950 hypothetical protein; hypothetical protein 2340608 7114782 Mchl_2226 Methylobacterium extorquens CM4 hypothetical protein YP_002421001.1 2339562 R 440085 CDS YP_002421002.1 218530186 7114784 complement(2341176..2342474) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_1951 major facilitator transporter; major facilitator superfamily protein 2342474 7114784 Mchl_2227 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421002.1 2341176 R 440085 CDS YP_002421003.1 218530187 7114785 2343094..2344476 1 NC_011757.1 PFAM: ethanolamine ammonia lyase large subunit; KEGG: mex:Mext_1952 ethanolamine ammonia lyase large subunit; ethanolamine ammonia lyase large subunit 2344476 7114785 Mchl_2228 Methylobacterium extorquens CM4 ethanolamine ammonia lyase large subunit YP_002421003.1 2343094 D 440085 CDS YP_002421004.1 218530188 7114786 2344473..2345267 1 NC_011757.1 PFAM: ethanolamine ammonia-lyase light chain; KEGG: mex:Mext_1953 ethanolamine ammonia-lyase; ethanolamine ammonia-lyase 2345267 7114786 Mchl_2229 Methylobacterium extorquens CM4 ethanolamine ammonia-lyase YP_002421004.1 2344473 D 440085 CDS YP_002421005.1 218530189 7114787 2345713..2347443 1 NC_011757.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2347443 7114787 Mchl_2230 Methylobacterium extorquens CM4 dihydroxy-acid dehydratase YP_002421005.1 2345713 D 440085 CDS YP_002421006.1 218530190 7114788 2347430..2348317 1 NC_011757.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mex:Mext_1955 Sel1 domain-containing protein; Sel1 domain-containing protein repeat-containing protein 2348317 7114788 Mchl_2231 Methylobacterium extorquens CM4 Sel1 domain-containing protein repeat-containing protein YP_002421006.1 2347430 D 440085 CDS YP_002421007.1 218530191 7114789 complement(2348349..2349143) 1 NC_011757.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase; KEGG: mex:Mext_1956 exodeoxyribonuclease III Xth; exodeoxyribonuclease III Xth 2349143 7114789 Mchl_2232 Methylobacterium extorquens CM4 exodeoxyribonuclease III Xth YP_002421007.1 2348349 R 440085 CDS YP_002421008.1 218530192 7114790 2349304..2349963 1 NC_011757.1 KEGG: mex:Mext_1957 hypothetical protein; hypothetical protein 2349963 7114790 Mchl_2233 Methylobacterium extorquens CM4 hypothetical protein YP_002421008.1 2349304 D 440085 CDS YP_002421009.1 218530193 7114791 complement(2350056..2351987) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_1958 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 2351987 7114791 Mchl_2234 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002421009.1 2350056 R 440085 CDS YP_002421010.1 218530194 7114792 complement(2352204..2352380) 1 NC_011757.1 PFAM: protein of unknown function DUF465; KEGG: mex:Mext_1959 hypothetical protein; hypothetical protein 2352380 7114792 Mchl_2235 Methylobacterium extorquens CM4 hypothetical protein YP_002421010.1 2352204 R 440085 CDS YP_002421011.1 218530195 7114793 2352632..2352853 1 NC_011757.1 PFAM: protein of unknown function DUF465; KEGG: mex:Mext_1960 hypothetical protein; hypothetical protein 2352853 7114793 Mchl_2236 Methylobacterium extorquens CM4 hypothetical protein YP_002421011.1 2352632 D 440085 CDS YP_002421012.1 218530196 7114794 complement(2353081..2353257) 1 NC_011757.1 KEGG: mex:Mext_1961 hypothetical protein; hypothetical protein 2353257 7114794 Mchl_2237 Methylobacterium extorquens CM4 hypothetical protein YP_002421012.1 2353081 R 440085 CDS YP_002421013.1 218530197 7114795 2353544..2354056 1 NC_011757.1 KEGG: mex:Mext_1962 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase, catalytic subunit 2354056 7114795 Mchl_2238 Methylobacterium extorquens CM4 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_002421013.1 2353544 D 440085 CDS YP_002421014.1 218530198 7114796 2354074..2355186 1 NC_011757.1 KEGG: mex:Mext_1963 phosphoribosylaminoimidazole carboxylase, ATPase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylaminoimidazole carboxylase, ATPase subunit 2355186 7114796 Mchl_2239 Methylobacterium extorquens CM4 phosphoribosylaminoimidazole carboxylase, ATPase subunit YP_002421014.1 2354074 D 440085 CDS YP_002421015.1 218530199 7114797 2355574..2356434 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: mex:Mext_1964 hypotheticalprotein; hypothetical protein 2356434 7114797 Mchl_2240 Methylobacterium extorquens CM4 hypothetical protein YP_002421015.1 2355574 D 440085 CDS YP_002421016.1 218530200 7114798 2356840..2357220 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_1965 response regulator receiver; response regulator receiver protein 2357220 7114798 Mchl_2241 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421016.1 2356840 D 440085 CDS YP_002421017.1 218530201 7114799 complement(2357291..2358286) 1 NC_011757.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 2358286 glpX 7114799 glpX Methylobacterium extorquens CM4 fructose 1,6-bisphosphatase II YP_002421017.1 2357291 R 440085 CDS YP_002421018.1 218530202 7114800 complement(2358523..2359845) 1 NC_011757.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 2359845 7114800 Mchl_2243 Methylobacterium extorquens CM4 homoserine dehydrogenase YP_002421018.1 2358523 R 440085 CDS YP_002421019.1 218530203 7114801 2360212..2360511 1 NC_011757.1 KEGG: mex:Mext_1968 hypothetical protein; hypothetical protein 2360511 7114801 Mchl_2244 Methylobacterium extorquens CM4 hypothetical protein YP_002421019.1 2360212 D 440085 CDS YP_002421020.1 218530204 7114802 complement(2360551..2361534) 1 NC_011757.1 KEGG: mex:Mext_1969 hypothetical protein; hypothetical protein 2361534 7114802 Mchl_2245 Methylobacterium extorquens CM4 hypothetical protein YP_002421020.1 2360551 R 440085 CDS YP_002421021.1 218530205 7114803 complement(2361642..2361998) 1 NC_011757.1 KEGG: mex:Mext_1970 hypothetical protein; hypothetical protein 2361998 7114803 Mchl_2246 Methylobacterium extorquens CM4 hypothetical protein YP_002421021.1 2361642 R 440085 CDS YP_002421022.1 218530206 7114804 complement(2362056..2363306) 1 NC_011757.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: mex:Mext_1971 Na+ dependent nucleoside transporter; Na+ dependent nucleoside transporter domain-containing protein 2363306 7114804 Mchl_2247 Methylobacterium extorquens CM4 Na+ dependent nucleoside transporter domain-containing protein YP_002421022.1 2362056 R 440085 CDS YP_002421023.1 218530207 7114805 complement(2363416..2364078) 1 NC_011757.1 KEGG: mex:Mext_1972 hypothetical protein; hypothetical protein 2364078 7114805 Mchl_2248 Methylobacterium extorquens CM4 hypothetical protein YP_002421023.1 2363416 R 440085 CDS YP_002421024.1 218530208 7114806 2364391..2364726 1 NC_011757.1 hypothetical protein 2364726 7114806 Mchl_2249 Methylobacterium extorquens CM4 hypothetical protein YP_002421024.1 2364391 D 440085 CDS YP_002421025.1 218530209 7114807 complement(2364780..2365928) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_1973 glycosyl transferase group 1; group 1 glycosyl transferase 2365928 7114807 Mchl_2250 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002421025.1 2364780 R 440085 CDS YP_002421026.1 218530210 7114808 2366012..2367214 1 NC_011757.1 KEGG: mex:Mext_1974 DNA topoisomerase I; DNA topoisomerase I 2367214 7114808 Mchl_2251 Methylobacterium extorquens CM4 DNA topoisomerase I YP_002421026.1 2366012 D 440085 CDS YP_002421027.1 218530211 7114809 complement(2367234..2368328) 1 NC_011757.1 PFAM: chemotaxis sensory transducer; KEGG: mex:Mext_1975 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2368328 7114809 Mchl_2252 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421027.1 2367234 R 440085 CDS YP_002421028.1 218530212 7114810 2368639..2370054 1 NC_011757.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: mex:Mext_1976 cytochrome bd ubiquinol oxidase subunit I; cytochrome bd ubiquinol oxidase subunit I 2370054 7114810 Mchl_2253 Methylobacterium extorquens CM4 cytochrome bd ubiquinol oxidase subunit I YP_002421028.1 2368639 D 440085 CDS YP_002421029.1 218530213 7114811 complement(2370147..2370854) 1 NC_011757.1 PFAM: regulatory protein LuxR; KEGG: mex:Mext_1977 regulatory protein LuxR; LuxR family transcriptional regulator 2370854 7114811 Mchl_2254 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002421029.1 2370147 R 440085 CDS YP_002421030.1 218530214 7114812 complement(2371036..2371932) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: mex:Mext_1978 diguanylate cyclase; response regulator receiver modulated diguanylate cyclase 2371932 7114812 Mchl_2255 Methylobacterium extorquens CM4 response regulator receiver modulated diguanylate cyclase YP_002421030.1 2371036 R 440085 CDS YP_002421031.1 218530215 7114813 complement(2372039..2372485) 1 NC_011757.1 KEGG: mex:Mext_1979 hypothetical protein; hypothetical protein 2372485 7114813 Mchl_2256 Methylobacterium extorquens CM4 hypothetical protein YP_002421031.1 2372039 R 440085 CDS YP_002421032.1 218530216 7114814 complement(2372650..2372898) 1 NC_011757.1 KEGG: mex:Mext_1980 hypothetical protein; hypothetical protein 2372898 7114814 Mchl_2257 Methylobacterium extorquens CM4 hypothetical protein YP_002421032.1 2372650 R 440085 CDS YP_002421033.1 218530217 7114815 2373352..2374182 1 NC_011757.1 PFAM: iron permease FTR1; KEGG: mex:Mext_1981 iron permease FTR1; iron permease FTR1 2374182 7114815 Mchl_2258 Methylobacterium extorquens CM4 iron permease FTR1 YP_002421033.1 2373352 D 440085 CDS YP_002421034.1 218530218 7114816 complement(2374291..2374764) 1 NC_011757.1 PFAM: protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_1982 low molecular weight phosphotyrosine protein phosphatase; protein-tyrosine phosphatase, low molecular weight 2374764 7114816 Mchl_2259 Methylobacterium extorquens CM4 protein-tyrosine phosphatase, low molecular weight YP_002421034.1 2374291 R 440085 CDS YP_002421035.1 218530219 7114817 complement(2375072..2375596) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_1983 hypothetical protein; hypothetical protein 2375596 7114817 Mchl_2260 Methylobacterium extorquens CM4 hypothetical protein YP_002421035.1 2375072 R 440085 CDS YP_002421036.1 218530220 7114818 complement(2375726..2377021) 1 NC_011757.1 PFAM: histidinol dehydrogenase; KEGG: mex:Mext_1984 histidinol dehydrogenase; histidinol dehydrogenase 2377021 7114818 Mchl_2261 Methylobacterium extorquens CM4 histidinol dehydrogenase YP_002421036.1 2375726 R 440085 CDS YP_002421037.1 218530221 7114819 complement(2377053..2377508) 1 NC_011757.1 KEGG: mex:Mext_1985 hypothetical protein; hypothetical protein 2377508 7114819 Mchl_2262 Methylobacterium extorquens CM4 hypothetical protein YP_002421037.1 2377053 R 440085 CDS YP_002421038.1 218530222 7114820 2377802..2378182 1 NC_011757.1 KEGG: mex:Mext_1986 hypothetical protein; hypothetical protein 2378182 7114820 Mchl_2263 Methylobacterium extorquens CM4 hypothetical protein YP_002421038.1 2377802 D 440085 CDS YP_002421039.1 218530223 7114821 complement(2378278..2379567) 1 NC_011757.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2379567 7114821 Mchl_2264 Methylobacterium extorquens CM4 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002421039.1 2378278 R 440085 CDS YP_002421040.1 218530224 7114822 complement(2379759..2379908) 1 NC_011757.1 KEGG: mpo:Mpop_1943 hypothetical protein; hypothetical protein 2379908 7114822 Mchl_2265 Methylobacterium extorquens CM4 hypothetical protein YP_002421040.1 2379759 R 440085 CDS YP_002421041.1 218530225 7114823 2380497..2381885 1 NC_011757.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 2381885 7114823 Mchl_2266 Methylobacterium extorquens CM4 5-aminolevulinate synthase YP_002421041.1 2380497 D 440085 CDS YP_002421042.1 218530226 7114824 2381925..2382131 1 NC_011757.1 KEGG: mex:Mext_1990 hypothetical protein; hypothetical protein 2382131 7114824 Mchl_2267 Methylobacterium extorquens CM4 hypothetical protein YP_002421042.1 2381925 D 440085 CDS YP_002421043.1 218530227 7114826 complement(2382602..2383156) 1 NC_011757.1 KEGG: mex:Mext_1992 hypothetical protein; hypothetical protein 2383156 7114826 Mchl_2269 Methylobacterium extorquens CM4 hypothetical protein YP_002421043.1 2382602 R 440085 CDS YP_002421044.1 218530228 7114827 2383362..2383667 1 NC_011757.1 PFAM: PhnA protein; KEGG: mpo:Mpop_1948 PhnA protein; PhnA protein 2383667 7114827 Mchl_2270 Methylobacterium extorquens CM4 PhnA protein YP_002421044.1 2383362 D 440085 CDS YP_002421045.1 218530229 7114828 complement(2383690..2384421) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_1994 beta-lactamase domain-containing protein; beta-lactamase 2384421 7114828 Mchl_2271 Methylobacterium extorquens CM4 beta-lactamase YP_002421045.1 2383690 R 440085 CDS YP_002421046.1 218530230 7114829 2384804..2385970 1 NC_011757.1 PFAM: regulatory protein LuxR; KEGG: mex:Mext_1995 regulatory protein LuxR; LuxR family transcriptional regulator 2385970 7114829 Mchl_2272 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002421046.1 2384804 D 440085 CDS YP_002421047.1 218530231 7114830 2386108..2387490 1 NC_011757.1 KEGG: mex:Mext_1996 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; phospho-2-dehydro-3-deoxyheptonate aldolase 2387490 7114830 Mchl_2273 Methylobacterium extorquens CM4 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002421047.1 2386108 D 440085 CDS YP_002421048.1 218530232 7114831 2387711..2387926 1 NC_011757.1 KEGG: mex:Mext_1997 hypothetical protein; hypothetical protein 2387926 7114831 Mchl_2274 Methylobacterium extorquens CM4 hypothetical protein YP_002421048.1 2387711 D 440085 CDS YP_002421049.1 218530233 7114832 complement(2388004..2388549) 1 NC_011757.1 KEGG: mex:Mext_1998 hypothetical protein; hypothetical protein 2388549 7114832 Mchl_2275 Methylobacterium extorquens CM4 hypothetical protein YP_002421049.1 2388004 R 440085 CDS YP_002421050.1 218530234 7114833 2388881..2389795 1 NC_011757.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: mex:Mext_1999 hypothetical protein; hypothetical protein 2389795 7114833 Mchl_2276 Methylobacterium extorquens CM4 hypothetical protein YP_002421050.1 2388881 D 440085 CDS YP_002421051.1 218530235 7114834 2389830..2390501 1 NC_011757.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2390501 gmk 7114834 gmk Methylobacterium extorquens CM4 guanylate kinase YP_002421051.1 2389830 D 440085 CDS YP_002421052.1 218530236 7114835 complement(2390548..2392296) 1 NC_011757.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: ATPase AAA; KEGG: mex:Mext_2001 ABC transporter related; ABC transporter 2392296 7114835 Mchl_2278 Methylobacterium extorquens CM4 ABC transporter YP_002421052.1 2390548 R 440085 CDS YP_002421053.1 218530237 7114836 complement(2392460..2392975) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2002 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 2392975 7114836 Mchl_2279 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421053.1 2392460 R 440085 CDS YP_002421054.1 218530238 7114837 complement(2393164..2393829) 1 NC_011757.1 KEGG: mex:Mext_2003 cob(II)yrinic acid a,c-diamide reductase; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; cob(II)yrinic acid a,c-diamide reductase 2393829 7114837 Mchl_2280 Methylobacterium extorquens CM4 cob(II)yrinic acid a,c-diamide reductase YP_002421054.1 2393164 R 440085 CDS YP_002421055.1 218530239 7114838 2394343..2394738 1 NC_011757.1 KEGG: mex:Mext_2004 hypothetical protein; hypothetical protein 2394738 7114838 Mchl_2281 Methylobacterium extorquens CM4 hypothetical protein YP_002421055.1 2394343 D 440085 CDS YP_002421056.1 218530240 7114839 complement(2394777..2396951) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2005 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 2396951 7114839 Mchl_2282 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002421056.1 2394777 R 440085 CDS YP_002421057.1 218530241 7114840 complement(2397456..2398076) 1 NC_011757.1 KEGG: mex:Mext_2006 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 2398076 7114840 Mchl_2283 Methylobacterium extorquens CM4 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_002421057.1 2397456 R 440085 CDS YP_002421058.1 218530242 7114841 complement(2398129..2399958) 1 NC_011757.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2399958 7114841 Mchl_2284 Methylobacterium extorquens CM4 phosphogluconate dehydratase YP_002421058.1 2398129 R 440085 CDS YP_002421059.1 218530243 7114842 complement(2400308..2401315) 1 NC_011757.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2401315 hslO 7114842 hslO Methylobacterium extorquens CM4 Hsp33-like chaperonin YP_002421059.1 2400308 R 440085 CDS YP_002421060.1 218530244 7114843 complement(2401575..2403686) 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_2010 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 2403686 7114843 Mchl_2286 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002421060.1 2401575 R 440085 CDS YP_002421061.1 218530245 7114844 complement(2404044..2404556) 1 NC_011757.1 KEGG: mex:Mext_2011 hypothetical protein; hypothetical protein 2404556 7114844 Mchl_2287 Methylobacterium extorquens CM4 hypothetical protein YP_002421061.1 2404044 R 440085 CDS YP_002421062.1 218530246 7114845 2404934..2405356 1 NC_011757.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2405356 ndk 7114845 ndk Methylobacterium extorquens CM4 nucleoside diphosphate kinase YP_002421062.1 2404934 D 440085 CDS YP_002421063.1 218530247 7114846 2405641..2406021 1 NC_011757.1 KEGG: mex:Mext_2013 hypothetical protein; hypothetical protein 2406021 7114846 Mchl_2289 Methylobacterium extorquens CM4 hypothetical protein YP_002421063.1 2405641 D 440085 CDS YP_002421064.1 218530248 7114847 complement(2406120..2407256) 1 NC_011757.1 PFAM: peptidase M48 Ste24p; KEGG: mex:Mext_2014 peptidase M48 Ste24p; peptidase M48 Ste24p 2407256 7114847 Mchl_2290 Methylobacterium extorquens CM4 peptidase M48 Ste24p YP_002421064.1 2406120 R 440085 CDS YP_002421065.1 218530249 7114848 complement(2407264..2407596) 1 NC_011757.1 KEGG: mex:Mext_2015 hypothetical protein; hypothetical protein 2407596 7114848 Mchl_2291 Methylobacterium extorquens CM4 hypothetical protein YP_002421065.1 2407264 R 440085 CDS YP_002421066.1 218530250 7114849 complement(2407632..2408552) 1 NC_011757.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: mex:Mext_2015 hypothetical protein; hypothetical protein 2408552 7114849 Mchl_2292 Methylobacterium extorquens CM4 hypothetical protein YP_002421066.1 2407632 R 440085 CDS YP_002421067.1 218530251 7114850 complement(2408941..2409174) 1 NC_011757.1 PFAM: protein of unknown function DUF466; KEGG: mex:Mext_2016 hypothetical protein; hypothetical protein 2409174 7114850 Mchl_2293 Methylobacterium extorquens CM4 hypothetical protein YP_002421067.1 2408941 R 440085 CDS YP_002421068.1 218530252 7114851 complement(2409182..2411239) 1 NC_011757.1 PFAM: carbon starvation protein CstA; KEGG: mex:Mext_2017 carbon starvation protein CstA; carbon starvation protein CstA 2411239 7114851 Mchl_2294 Methylobacterium extorquens CM4 carbon starvation protein CstA YP_002421068.1 2409182 R 440085 CDS YP_002421069.1 218530253 7114852 complement(2411539..2412165) 1 NC_011757.1 PFAM: protein of unknown function DUF477; KEGG: mex:Mext_2018 hypothetical protein; hypothetical protein 2412165 7114852 Mchl_2295 Methylobacterium extorquens CM4 hypothetical protein YP_002421069.1 2411539 R 440085 CDS YP_002421070.1 218530254 7116958 complement(2412155..2412940) 1 NC_011757.1 PFAM: protein of unknown function DUF477; KEGG: mex:Mext_2019 hypothetical protein; hypothetical protein 2412940 7116958 Mchl_2296 Methylobacterium extorquens CM4 hypothetical protein YP_002421070.1 2412155 R 440085 CDS YP_002421071.1 218530255 7116959 complement(2412960..2413595) 1 NC_011757.1 PFAM: LemA family protein; KEGG: mex:Mext_2020 LemA family protein; LemA family protein 2413595 7116959 Mchl_2297 Methylobacterium extorquens CM4 LemA family protein YP_002421071.1 2412960 R 440085 CDS YP_002421072.1 218530256 7116793 2413840..2414154 1 NC_011757.1 TIGRFAM: conserved hypothetical protein; PFAM: Selenoprotein W-related; KEGG: mex:Mext_2021 selenoprotein; hypothetical protein 2414154 7116793 Mchl_2298 Methylobacterium extorquens CM4 hypothetical protein YP_002421072.1 2413840 D 440085 CDS YP_002421073.1 218530257 7116877 2414254..2416395 1 NC_011757.1 KEGG: mex:Mext_2022 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; signal transduction histidine kinase 2416395 7116877 Mchl_2299 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002421073.1 2414254 D 440085 CDS YP_002421074.1 218530258 7116878 complement(2416427..2417263) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_2023 2,5-didehydrogluconate reductase; 2,5-didehydrogluconate reductase 2417263 7116878 Mchl_2300 Methylobacterium extorquens CM4 2,5-didehydrogluconate reductase YP_002421074.1 2416427 R 440085 CDS YP_002421075.1 218530259 7116879 complement(2417378..2418157) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_2024 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 2418157 7116879 Mchl_2301 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002421075.1 2417378 R 440085 CDS YP_002421076.1 218530260 7116880 complement(2418383..2419915) 1 NC_011757.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 2419915 glgA 7116880 glgA Methylobacterium extorquens CM4 glycogen synthase YP_002421076.1 2418383 R 440085 CDS YP_002421077.1 218530261 7116881 complement(2420443..2421789) 1 NC_011757.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: mpo:Mpop_1988 alpha amylase catalytic region; alpha amylase catalytic subunit 2421789 7116881 Mchl_2303 Methylobacterium extorquens CM4 alpha amylase catalytic subunit YP_002421077.1 2420443 R 440085 CDS YP_002421078.1 218530262 7116882 2422117..2424651 1 NC_011757.1 KEGG: mex:Mext_2028 glycogen/starch/alpha-glucan phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; glycogen/starch/alpha-glucan phosphorylase 2424651 7116882 Mchl_2304 Methylobacterium extorquens CM4 glycogen/starch/alpha-glucan phosphorylase YP_002421078.1 2422117 D 440085 CDS YP_002421079.1 218530263 7116883 complement(2424828..2425769) 1 NC_011757.1 KEGG: mex:Mext_2030 ferredoxin-NAD reductase component; ferredoxin-NAD reductase component 2425769 7116883 Mchl_2305 Methylobacterium extorquens CM4 ferredoxin-NAD reductase component YP_002421079.1 2424828 R 440085 CDS YP_002421080.1 218530264 7116884 complement(2425813..2426241) 1 NC_011757.1 KEGG: mex:Mext_2031 hypothetical protein; hypothetical protein 2426241 7116884 Mchl_2306 Methylobacterium extorquens CM4 hypothetical protein YP_002421080.1 2425813 R 440085 CDS YP_002421081.1 218530265 7116885 complement(2426362..2429514) 1 NC_011757.1 KEGG: mex:Mext_2032 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein; diguanylate cyclase/phosphodiesterase 2429514 7116885 Mchl_2307 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002421081.1 2426362 R 440085 CDS YP_002421082.1 218530266 7116886 2429593..2430624 1 NC_011757.1 PFAM: glycosyl transferase family 4; KEGG: mex:Mext_2033 glycosyl transferase; glycosyl transferase family protein 2430624 7116886 Mchl_2308 Methylobacterium extorquens CM4 glycosyl transferase family protein YP_002421082.1 2429593 D 440085 CDS YP_002421083.1 218530267 7116887 2430636..2431559 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: mex:Mext_2034 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 2431559 7116887 Mchl_2309 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002421083.1 2430636 D 440085 CDS YP_002421084.1 218530268 7116888 complement(2431564..2432175) 1 NC_011757.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: mex:Mext_2035 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 2432175 7116888 Mchl_2310 Methylobacterium extorquens CM4 NAD(P)H dehydrogenase (quinone) YP_002421084.1 2431564 R 440085 CDS YP_002421085.1 218530269 7116889 2432252..2432659 1 NC_011757.1 PFAM: helix-turn-helix HxlR type; KEGG: mex:Mext_2036 helix-turn-helix HxlR type; HxlR family transcriptional regulator 2432659 7116889 Mchl_2311 Methylobacterium extorquens CM4 HxlR family transcriptional regulator YP_002421085.1 2432252 D 440085 CDS YP_002421086.1 218530270 7116890 complement(2432679..2434652) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KR domain protein; KEGG: mex:Mext_2037 polysaccharide biosynthesis protein CapD; polysaccharide biosynthesis protein CapD 2434652 7116890 Mchl_2312 Methylobacterium extorquens CM4 polysaccharide biosynthesis protein CapD YP_002421086.1 2432679 R 440085 CDS YP_002421087.1 218530271 7116891 complement(2434756..2435607) 1 NC_011757.1 PFAM: protein of unknown function DUF1206; KEGG: mex:Mext_2038 hypothetical protein; hypothetical protein 2435607 7116891 Mchl_2313 Methylobacterium extorquens CM4 hypothetical protein YP_002421087.1 2434756 R 440085 CDS YP_002421088.1 218530272 7116892 complement(2435614..2435955) 1 NC_011757.1 KEGG: mex:Mext_2039 hypothetical protein; hypothetical protein 2435955 7116892 Mchl_2314 Methylobacterium extorquens CM4 hypothetical protein YP_002421088.1 2435614 R 440085 CDS YP_002421089.1 218530273 7116893 complement(2435981..2436547) 1 NC_011757.1 PFAM: protein of unknown function DUF820; KEGG: mex:Mext_2040 hypothetical protein; hypothetical protein 2436547 7116893 Mchl_2315 Methylobacterium extorquens CM4 hypothetical protein YP_002421089.1 2435981 R 440085 CDS YP_002421090.1 218530274 7116895 complement(2437266..2438714) 1 NC_011757.1 PFAM: homospermidine synthase; KEGG: mex:Mext_2042 homospermidine synthase; Homospermidine synthase 2438714 7116895 Mchl_2317 Methylobacterium extorquens CM4 Homospermidine synthase YP_002421090.1 2437266 R 440085 CDS YP_002421091.1 218530275 7116896 2438988..2439176 1 NC_011757.1 KEGG: mex:Mext_2043 hypothetical protein; hypothetical protein 2439176 7116896 Mchl_2318 Methylobacterium extorquens CM4 hypothetical protein YP_002421091.1 2438988 D 440085 CDS YP_002421092.1 218530276 7116897 complement(2439324..2439881) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_2044 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 2439881 7116897 Mchl_2319 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002421092.1 2439324 R 440085 CDS YP_002421093.1 218530277 7116898 complement(2440060..2441226) 1 NC_011757.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mex:Mext_2045 Orn/DAP/Arg decarboxylase 2; ornithine decarboxylase 2441226 7116898 Mchl_2320 Methylobacterium extorquens CM4 ornithine decarboxylase YP_002421093.1 2440060 R 440085 CDS YP_002421094.1 218530278 7116899 2441911..2443530 1 NC_011757.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 2443530 mdoG 7116899 mdoG Methylobacterium extorquens CM4 glucan biosynthesis protein G YP_002421094.1 2441911 D 440085 CDS YP_002421095.1 218530279 7116900 2443503..2444039 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_2047 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 2444039 7116900 Mchl_2322 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002421095.1 2443503 D 440085 CDS YP_002421096.1 218530280 7116901 2444183..2445271 1 NC_011757.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: mex:Mext_2048 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 2445271 7116901 Mchl_2323 Methylobacterium extorquens CM4 NADH:flavin oxidoreductase/NADH oxidase YP_002421096.1 2444183 D 440085 CDS YP_002421097.1 218530281 7116902 2445367..2446065 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase; KEGG: mex:Mext_2049 HAD family hydrolase; HAD-superfamily hydrolase 2446065 7116902 Mchl_2324 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002421097.1 2445367 D 440085 CDS YP_002421098.1 218530282 7116903 complement(2446059..2446556) 1 NC_011757.1 PFAM: SmpA/OmlA domain protein; KEGG: mex:Mext_2050 SmpA/OmlA domain-containing protein; SmpA/OmlA domain-containing protein 2446556 7116903 Mchl_2325 Methylobacterium extorquens CM4 SmpA/OmlA domain-containing protein YP_002421098.1 2446059 R 440085 CDS YP_002421099.1 218530283 7116904 2446714..2447280 1 NC_011757.1 KEGG: mex:Mext_2051 ubiquinol-cytochrome C chaperone; ubiquinol-cytochrome C chaperone 2447280 7116904 Mchl_2326 Methylobacterium extorquens CM4 ubiquinol-cytochrome C chaperone YP_002421099.1 2446714 D 440085 CDS YP_002421100.1 218530284 7116905 2447277..2447795 1 NC_011757.1 KEGG: mex:Mext_2052 hypothetical protein; hypothetical protein 2447795 7116905 Mchl_2327 Methylobacterium extorquens CM4 hypothetical protein YP_002421100.1 2447277 D 440085 CDS YP_002421101.1 218530285 7116906 2447960..2449018 1 NC_011757.1 TIGRFAM: fatty acid/phospholipid synthesis protein PlsX; PFAM: fatty acid synthesis plsX protein; KEGG: mex:Mext_2053 fatty acid/phospholipid synthesis protein PlsX; fatty acid/phospholipid synthesis protein PlsX 2449018 7116906 Mchl_2328 Methylobacterium extorquens CM4 fatty acid/phospholipid synthesis protein PlsX YP_002421101.1 2447960 D 440085 CDS YP_002421102.1 218530286 7116907 2449052..2450032 1 NC_011757.1 KEGG: mex:Mext_2054 3-oxoacyl-(acyl-carrier-protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III 2450032 7116907 Mchl_2329 Methylobacterium extorquens CM4 3-oxoacyl-(acyl-carrier-protein) synthase III YP_002421102.1 2449052 D 440085 CDS YP_002421103.1 218530287 7116908 2450241..2450567 1 NC_011757.1 PFAM: histone family protein DNA-binding protein; KEGG: mex:Mext_2055 histone family protein DNA-binding protein; histone family protein DNA-binding protein 2450567 7116908 Mchl_2330 Methylobacterium extorquens CM4 histone family protein DNA-binding protein YP_002421103.1 2450241 D 440085 CDS YP_002421104.1 218530288 7116909 2450621..2451103 1 NC_011757.1 PFAM: regulatory protein MerR; KEGG: mex:Mext_2056 regulatory protein MerR; MerR family transcriptional regulator 2451103 7116909 Mchl_2331 Methylobacterium extorquens CM4 MerR family transcriptional regulator YP_002421104.1 2450621 D 440085 CDS YP_002421105.1 218530289 7116910 2451246..2451665 1 NC_011757.1 KEGG: mex:Mext_2057 hypothetical protein; hypothetical protein 2451665 7116910 Mchl_2332 Methylobacterium extorquens CM4 hypothetical protein YP_002421105.1 2451246 D 440085 CDS YP_002421106.1 218530290 7116911 2451807..2452280 1 NC_011757.1 KEGG: mex:Mext_2058 hypothetical protein; hypothetical protein 2452280 7116911 Mchl_2333 Methylobacterium extorquens CM4 hypothetical protein YP_002421106.1 2451807 D 440085 CDS YP_002421107.1 218530291 7116912 2452540..2454492 1 NC_011757.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: mex:Mext_2059 serine protein kinase domain-containing protein; serine protein kinase, PrkA 2454492 7116912 Mchl_2334 Methylobacterium extorquens CM4 serine protein kinase, PrkA YP_002421107.1 2452540 D 440085 CDS YP_002421108.1 218530292 7116913 2454596..2455900 1 NC_011757.1 PFAM: protein of unknown function DUF444; KEGG: mex:Mext_2060 hypothetical protein; hypothetical protein 2455900 7116913 Mchl_2335 Methylobacterium extorquens CM4 hypothetical protein YP_002421108.1 2454596 D 440085 CDS YP_002421109.1 218530293 7116914 2455948..2457519 1 NC_011757.1 PFAM: SpoVR family protein; KEGG: mex:Mext_2061 hypothetical protein; SpoVR family protein 2457519 7116914 Mchl_2336 Methylobacterium extorquens CM4 SpoVR family protein YP_002421109.1 2455948 D 440085 CDS YP_002421110.1 218530294 7116915 complement(2457696..2458355) 1 NC_011757.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; KEGG: mex:Mext_2062 phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase 2458355 7116915 Mchl_2337 Methylobacterium extorquens CM4 phosphoribosylglycinamide formyltransferase YP_002421110.1 2457696 R 440085 CDS YP_002421111.1 218530295 7116916 complement(2458352..2459419) 1 NC_011757.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2459419 7116916 Mchl_2338 Methylobacterium extorquens CM4 phosphoribosylaminoimidazole synthetase YP_002421111.1 2458352 R 440085 CDS YP_002421112.1 218530296 7116917 2459751..2460863 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_2065 hypothetical protein; hypothetical protein 2460863 7116917 Mchl_2339 Methylobacterium extorquens CM4 hypothetical protein YP_002421112.1 2459751 D 440085 CDS YP_002421113.1 218530297 7116918 2460985..2461743 1 NC_011757.1 KEGG: mex:Mext_2066 chromosomal replication initiator DnaA; chromosomal replication initiator DnaA 2461743 7116918 Mchl_2340 Methylobacterium extorquens CM4 chromosomal replication initiator DnaA YP_002421113.1 2460985 D 440085 CDS YP_002421114.1 218530298 7116919 2461883..2464249 1 NC_011757.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2464249 7116919 Mchl_2341 Methylobacterium extorquens CM4 polyphosphate kinase YP_002421114.1 2461883 D 440085 CDS YP_002421115.1 218530299 7116920 2464403..2465956 1 NC_011757.1 PFAM: Ppx/GppA phosphatase; KEGG: mex:Mext_2068 Ppx/GppA phosphatase; Ppx/GppA phosphatase 2465956 7116920 Mchl_2342 Methylobacterium extorquens CM4 Ppx/GppA phosphatase YP_002421115.1 2464403 D 440085 CDS YP_002421116.1 218530300 7116921 complement(2466035..2466334) 1 NC_011757.1 KEGG: mex:Mext_2069 hypothetical protein; hypothetical protein 2466334 7116921 Mchl_2343 Methylobacterium extorquens CM4 hypothetical protein YP_002421116.1 2466035 R 440085 CDS YP_002421117.1 218530301 7116922 complement(2466851..2468053) 1 NC_011757.1 PFAM: aminotransferase class I and II; KEGG: mex:Mext_2070 aminotransferase class I and II; class I and II aminotransferase 2468053 7116922 Mchl_2344 Methylobacterium extorquens CM4 class I and II aminotransferase YP_002421117.1 2466851 R 440085 CDS YP_002421118.1 218530302 7116923 2468494..2470476 1 NC_011757.1 PFAM: coenzyme A transferase; KEGG: mex:Mext_2071 coenzyme A transferase; coenzyme A transferase 2470476 7116923 Mchl_2345 Methylobacterium extorquens CM4 coenzyme A transferase YP_002421118.1 2468494 D 440085 CDS YP_002421119.1 218530303 7116924 2470853..2472523 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_2072 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2472523 7116924 Mchl_2346 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421119.1 2470853 D 440085 CDS YP_002421120.1 218530304 7116925 2472761..2473828 1 NC_011757.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2473828 rpsB 7116925 rpsB Methylobacterium extorquens CM4 30S ribosomal protein S2 YP_002421120.1 2472761 D 440085 CDS YP_002421121.1 218530305 7116926 2473973..2474893 1 NC_011757.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2474893 tsf 7116926 tsf Methylobacterium extorquens CM4 elongation factor Ts YP_002421121.1 2473973 D 440085 CDS YP_002421122.1 218530306 7116927 2475060..2475782 1 NC_011757.1 TIGRFAM: uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: mex:Mext_2075 uridylate kinase; uridylate kinase 2475782 7116927 Mchl_2349 Methylobacterium extorquens CM4 uridylate kinase YP_002421122.1 2475060 D 440085 CDS YP_002421123.1 218530307 7116928 complement(2475892..2476431) 1 NC_011757.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 2476431 7116928 Mchl_2350 Methylobacterium extorquens CM4 inorganic pyrophosphatase YP_002421123.1 2475892 R 440085 CDS YP_002421124.1 218530308 7116929 complement(2476718..2477224) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_2077 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 2477224 7116929 Mchl_2351 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002421124.1 2476718 R 440085 CDS YP_002421125.1 218530309 7116930 2477362..2478087 1 NC_011757.1 KEGG: mex:Mext_2078 hypothetical protein; protein tyrosine/serine phosphatase 2478087 7116930 Mchl_2352 Methylobacterium extorquens CM4 protein tyrosine/serine phosphatase YP_002421125.1 2477362 D 440085 CDS YP_002421126.1 218530310 7116931 2478096..2479091 1 NC_011757.1 KEGG: mex:Mext_2079 hypothetical protein; hypothetical protein 2479091 7116931 Mchl_2353 Methylobacterium extorquens CM4 hypothetical protein YP_002421126.1 2478096 D 440085 CDS YP_002421127.1 218530311 7116932 complement(2479152..2480207) 1 NC_011757.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 2480207 lpxD 7116932 lpxD Methylobacterium extorquens CM4 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002421127.1 2479152 R 440085 CDS YP_002421128.1 218530312 7116933 complement(2480370..2482934) 1 NC_011757.1 TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: mex:Mext_2081 outer membrane protein assembly complex, YaeT protein; outer membrane protein assembly complex, YaeT protein 2482934 7116933 Mchl_2355 Methylobacterium extorquens CM4 outer membrane protein assembly complex, YaeT protein YP_002421128.1 2480370 R 440085 CDS YP_002421129.1 218530313 7116934 complement(2483295..2484455) 1 NC_011757.1 KEGG: mex:Mext_2082 membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; membrane-associated zinc metalloprotease 2484455 7116934 Mchl_2356 Methylobacterium extorquens CM4 membrane-associated zinc metalloprotease YP_002421129.1 2483295 R 440085 CDS YP_002421130.1 218530314 7116935 complement(2484672..2485850) 1 NC_011757.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2485850 7116935 Mchl_2357 Methylobacterium extorquens CM4 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002421130.1 2484672 R 440085 CDS YP_002421131.1 218530315 7116936 complement(2485865..2486725) 1 NC_011757.1 PFAM: phosphatidate cytidylyltransferase; KEGG: mex:Mext_2084 phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase 2486725 7116936 Mchl_2358 Methylobacterium extorquens CM4 phosphatidate cytidylyltransferase YP_002421131.1 2485865 R 440085 CDS YP_002421132.1 218530316 7116937 complement(2486725..2487504) 1 NC_011757.1 KEGG: mex:Mext_2085 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 2487504 7116937 Mchl_2359 Methylobacterium extorquens CM4 undecaprenyl diphosphate synthase YP_002421132.1 2486725 R 440085 CDS YP_002421133.1 218530317 7116938 complement(2487575..2488138) 1 NC_011757.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 2488138 frr 7116938 frr Methylobacterium extorquens CM4 ribosome recycling factor YP_002421133.1 2487575 R 440085 CDS YP_002421134.1 218530318 7116939 2488471..2489610 1 NC_011757.1 PFAM: CBS domain containing protein; HPP family protein; KEGG: mex:Mext_2087 HPP family protein?; CBS domain-containing membrane protein 2489610 7116939 Mchl_2361 Methylobacterium extorquens CM4 CBS domain-containing membrane protein YP_002421134.1 2488471 D 440085 CDS YP_002421135.1 218530319 7116940 2489781..2489876 1 NC_011757.1 KEGG: met:M446_6426 hypothetical protein; hypothetical protein 2489876 7116940 Mchl_2362 Methylobacterium extorquens CM4 hypothetical protein YP_002421135.1 2489781 D 440085 CDS YP_002421136.1 218530320 7116941 complement(2489949..2491229) 1 NC_011757.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_2088 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6 family Ubiquinone biosynthesis hydroxylase 2491229 7116941 Mchl_2363 Methylobacterium extorquens CM4 UbiH/UbiF/VisC/COQ6 family Ubiquinone biosynthesis hydroxylase YP_002421136.1 2489949 R 440085 CDS YP_002421137.1 218530321 7116942 2491622..2492566 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_2089 LysR substrate-binding; LysR family transcriptional regulator 2492566 7116942 Mchl_2364 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002421137.1 2491622 D 440085 CDS YP_002421138.1 218530322 7116943 2492812..2493561 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_2090 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2493561 7116943 Mchl_2365 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002421138.1 2492812 D 440085 CDS YP_002421139.1 218530323 7116944 2493579..2494439 1 NC_011757.1 PFAM: transketolase; KEGG: mex:Mext_2091 transketolase domain-containing protein; transketolase 2494439 7116944 Mchl_2366 Methylobacterium extorquens CM4 transketolase YP_002421139.1 2493579 D 440085 CDS YP_002421140.1 218530324 7116945 2494436..2495455 1 NC_011757.1 PFAM: transketolase; transketolase domain protein; KEGG: mex:Mext_2092 transketolase; transketolase 2495455 7116945 Mchl_2367 Methylobacterium extorquens CM4 transketolase YP_002421140.1 2494436 D 440085 CDS YP_002421141.1 218530325 7116946 2495618..2496634 1 NC_011757.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: mex:Mext_2093 TRAP dicarboxylate transporter DctP subunit; TRAP dicarboxylate transporter subunit DctP 2496634 7116946 Mchl_2368 Methylobacterium extorquens CM4 TRAP dicarboxylate transporter subunit DctP YP_002421141.1 2495618 D 440085 CDS YP_002421142.1 218530326 7116947 2496646..2498532 1 NC_011757.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: mex:Mext_2094 TRAP C4-dicarboxylate transporter permease DctM subunit; TRAP dicarboxylate transporter subunit DctM 2498532 7116947 Mchl_2369 Methylobacterium extorquens CM4 TRAP dicarboxylate transporter subunit DctM YP_002421142.1 2496646 D 440085 CDS YP_002421143.1 218530327 7116948 complement(2498614..2498790) 1 NC_011757.1 hypothetical protein 2498790 7116948 Mchl_2370 Methylobacterium extorquens CM4 hypothetical protein YP_002421143.1 2498614 R 440085 CDS YP_002421144.1 218530328 7116949 2499237..2500127 1 NC_011757.1 KEGG: mex:Mext_2095 hypothetical protein; hypothetical protein 2500127 7116949 Mchl_2371 Methylobacterium extorquens CM4 hypothetical protein YP_002421144.1 2499237 D 440085 CDS YP_002421145.1 218530329 7116950 complement(2500367..2508757) 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; Na-Ca exchanger/integrin-beta4; endonuclease/exonuclease/phosphatase; 5'-nucleotidase domain protein; KEGG: rpb:RPB_0803 5'-nucleotidase; 5'-nucleotidase domain-containing protein 2508757 7116950 Mchl_2372 Methylobacterium extorquens CM4 5'-nucleotidase domain-containing protein YP_002421145.1 2500367 R 440085 CDS YP_002421146.1 218530330 7116951 2509178..2510041 1 NC_011757.1 PFAM: acyl-CoA thioesterase; KEGG: mex:Mext_2097 acyl-CoA thioesterase II; Palmitoyl-CoA hydrolase 2510041 7116951 Mchl_2373 Methylobacterium extorquens CM4 Palmitoyl-CoA hydrolase YP_002421146.1 2509178 D 440085 CDS YP_002421147.1 218530331 7116952 2510304..2510642 1 NC_011757.1 PFAM: nitrogen regulatory protein P-II; KEGG: mex:Mext_2098 nitrogen regulatory protein P-II; nitrogen regulatory protein P-II 2510642 7116952 Mchl_2374 Methylobacterium extorquens CM4 nitrogen regulatory protein P-II YP_002421147.1 2510304 D 440085 CDS YP_002421148.1 218530332 7116953 2510775..2512271 1 NC_011757.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: mex:Mext_2099 ammonium transporter; ammonium transporter 2512271 7116953 Mchl_2375 Methylobacterium extorquens CM4 ammonium transporter YP_002421148.1 2510775 D 440085 CDS YP_002421149.1 218530333 7116954 2512613..2513875 1 NC_011757.1 KEGG: mex:Mext_2100 hypothetical protein; hypothetical protein 2513875 7116954 Mchl_2376 Methylobacterium extorquens CM4 hypothetical protein YP_002421149.1 2512613 D 440085 CDS YP_002421150.1 218530334 7116955 2514057..2516672 1 NC_011757.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: mex:Mext_2101 cell divisionFtsK/SpoIIIE; cell division FtsK/SpoIIIE 2516672 7116955 Mchl_2377 Methylobacterium extorquens CM4 cell division FtsK/SpoIIIE YP_002421150.1 2514057 D 440085 CDS YP_002421151.1 218530335 7116956 2516823..2518982 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2102 TonB-dependent receptor plug; TonB-dependent receptor 2518982 7116956 Mchl_2378 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002421151.1 2516823 D 440085 CDS YP_002421152.1 218530336 7116957 2519338..2521305 1 NC_011757.1 KEGG: mex:Mext_2103 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 2521305 7116957 Mchl_2379 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002421152.1 2519338 D 440085 CDS YP_002421153.1 218530337 7117780 complement(2521530..2521832) 1 NC_011757.1 KEGG: mex:Mext_2104 hypothetical protein; hypothetical protein 2521832 7117780 Mchl_2380 Methylobacterium extorquens CM4 hypothetical protein YP_002421153.1 2521530 R 440085 CDS YP_002421154.1 218530338 7113736 complement(2521850..2524168) 1 NC_011757.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: mex:Mext_2105 oxidoreductase alpha (molybdopterin) subunit; oxidoreductase alpha (molybdopterin) subunit 2524168 7113736 Mchl_2381 Methylobacterium extorquens CM4 oxidoreductase alpha (molybdopterin) subunit YP_002421154.1 2521850 R 440085 CDS YP_002421155.1 218530339 7113737 complement(2524691..2525767) 1 NC_011757.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2525767 7113737 Mchl_2382 Methylobacterium extorquens CM4 dihydroorotate dehydrogenase YP_002421155.1 2524691 R 440085 CDS YP_002421156.1 218530340 7113738 complement(2525764..2526114) 1 NC_011757.1 PFAM: protein of unknown function DUF952; KEGG: mex:Mext_2107 hypothetical protein; hypothetical protein 2526114 7113738 Mchl_2383 Methylobacterium extorquens CM4 hypothetical protein YP_002421156.1 2525764 R 440085 CDS YP_002421157.1 218530341 7113739 2526337..2526969 1 NC_011757.1 PFAM: peptidase S24 and S26 domain protein; KEGG: mex:Mext_2108 peptidase S24/S26 domain-containing protein; phage repressor 2526969 7113739 Mchl_2384 Methylobacterium extorquens CM4 phage repressor YP_002421157.1 2526337 D 440085 CDS YP_002421158.1 218530342 7113740 complement(2526980..2527309) 1 NC_011757.1 KEGG: mex:Mext_2109 hypothetical protein; hypothetical protein 2527309 7113740 Mchl_2385 Methylobacterium extorquens CM4 hypothetical protein YP_002421158.1 2526980 R 440085 CDS YP_002421159.1 218530343 7113741 complement(2527480..2527695) 1 NC_011757.1 KEGG: mpo:Mpop_2062 hypothetical protein; hypothetical protein 2527695 7113741 Mchl_2386 Methylobacterium extorquens CM4 hypothetical protein YP_002421159.1 2527480 R 440085 CDS YP_002421160.1 218530344 7113742 complement(2527831..2528691) 1 NC_011757.1 KEGG: mex:Mext_2111 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; serine O-acetyltransferase 2528691 7113742 Mchl_2387 Methylobacterium extorquens CM4 serine O-acetyltransferase YP_002421160.1 2527831 R 440085 CDS YP_002421161.1 218530345 7113743 complement(2528973..2529872) 1 NC_011757.1 consists of N-terminal helix-turn-helix domain and C-terminal shikimate kinase-like domain which may bind benzoyl-CoA; controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate; anaerobic benzoate catabolism transcriptional regulator 2529872 7113743 Mchl_2388 Methylobacterium extorquens CM4 anaerobic benzoate catabolism transcriptional regulator YP_002421161.1 2528973 R 440085 CDS YP_002421162.1 218530346 7113745 complement(2530536..2532809) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: mex:Mext_2113 ATPase domain-containing protein; histidine kinase 2532809 7113745 Mchl_2390 Methylobacterium extorquens CM4 histidine kinase YP_002421162.1 2530536 R 440085 CDS YP_002421163.1 218530347 7113746 complement(2532931..2533134) 1 NC_011757.1 KEGG: mex:Mext_2114 hypothetical protein; hypothetical protein 2533134 7113746 Mchl_2391 Methylobacterium extorquens CM4 hypothetical protein YP_002421163.1 2532931 R 440085 CDS YP_002421164.1 218530348 7113747 complement(2533146..2533430) 1 NC_011757.1 KEGG: mex:Mext_2115 hypothetical protein; hypothetical protein 2533430 7113747 Mchl_2392 Methylobacterium extorquens CM4 hypothetical protein YP_002421164.1 2533146 R 440085 CDS YP_002421165.1 218530349 7113748 complement(2533586..2534320) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_2116 response regulator receiver; transcriptional regulator 2534320 7113748 Mchl_2393 Methylobacterium extorquens CM4 transcriptional regulator YP_002421165.1 2533586 R 440085 CDS YP_002421166.1 218530350 7113749 2534735..2536516 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_2117 histidine kinase; response regulator receiver sensor signal transduction histidine kinase 2536516 7113749 Mchl_2394 Methylobacterium extorquens CM4 response regulator receiver sensor signal transduction histidine kinase YP_002421166.1 2534735 D 440085 CDS YP_002421167.1 218530351 7113750 complement(2536603..2536986) 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_2118 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2536986 7113750 Mchl_2395 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002421167.1 2536603 R 440085 CDS YP_002421168.1 218530352 7113752 complement(2537510..2538241) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_2120 cyclic nucleotide-binding; cyclic nucleotide-binding protein 2538241 7113752 Mchl_2397 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002421168.1 2537510 R 440085 CDS YP_002421169.1 218530353 7113753 complement(2538425..2539621) 1 NC_011757.1 PFAM: PepSY-associated TM helix domain protein; KEGG: mex:Mext_2121 PepSY-associated TM helix domain-containing protein; PepSY-associated TM helix domain-containing protein 2539621 7113753 Mchl_2398 Methylobacterium extorquens CM4 PepSY-associated TM helix domain-containing protein YP_002421169.1 2538425 R 440085 CDS YP_002421170.1 218530354 7113754 complement(2539676..2541856) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2122 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 2541856 7113754 Mchl_2399 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002421170.1 2539676 R 440085 CDS YP_002421171.1 218530355 7113755 2542201..2542701 1 NC_011757.1 KEGG: mex:Mext_2123 hypothetical protein; hypothetical protein 2542701 7113755 Mchl_2400 Methylobacterium extorquens CM4 hypothetical protein YP_002421171.1 2542201 D 440085 CDS YP_002421172.1 218530356 7113756 2542912..2543517 1 NC_011757.1 PFAM: oxidoreductase molybdopterin binding; KEGG: mex:Mext_2124 oxidoreductase molybdopterin binding; molybdopterin binding oxidoreductase 2543517 7113756 Mchl_2401 Methylobacterium extorquens CM4 molybdopterin binding oxidoreductase YP_002421172.1 2542912 D 440085 CDS YP_002421173.1 218530357 7113757 2543531..2544262 1 NC_011757.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: mex:Mext_2125 oxidoreductase FAD-binding subunit; oxidoreductase FAD-binding domain-containing protein 2544262 7113757 Mchl_2402 Methylobacterium extorquens CM4 oxidoreductase FAD-binding domain-containing protein YP_002421173.1 2543531 D 440085 CDS YP_002421174.1 218530358 7113758 complement(2544445..2544822) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_2126 hypothetical protein; hypothetical protein 2544822 7113758 Mchl_2403 Methylobacterium extorquens CM4 hypothetical protein YP_002421174.1 2544445 R 440085 CDS YP_002421175.1 218530359 7113759 complement(2545003..2545275) 1 NC_011757.1 KEGG: mpo:Mpop_2084 hypothetical protein; hypothetical protein 2545275 7113759 Mchl_2404 Methylobacterium extorquens CM4 hypothetical protein YP_002421175.1 2545003 R 440085 CDS YP_002421176.1 218530360 7113760 2545650..2547011 1 NC_011757.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 2547011 7113760 Mchl_2405 Methylobacterium extorquens CM4 3-phosphoshikimate 1-carboxyvinyltransferase YP_002421176.1 2545650 D 440085 CDS YP_002421177.1 218530361 7113761 2547008..2547676 1 NC_011757.1 KEGG: mex:Mext_2129 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; cytidylate kinase 2547676 7113761 Mchl_2406 Methylobacterium extorquens CM4 cytidylate kinase YP_002421177.1 2547008 D 440085 CDS YP_002421178.1 218530362 7113762 complement(2547688..2548005) 1 NC_011757.1 PFAM: protein of unknown function DUF167; KEGG: mex:Mext_2130 hypothetical protein; hypothetical protein 2548005 7113762 Mchl_2407 Methylobacterium extorquens CM4 hypothetical protein YP_002421178.1 2547688 R 440085 CDS YP_002421179.1 218530363 7113764 2548800..2550098 1 NC_011757.1 KEGG: mex:Mext_2131 hypothetical protein; hypothetical protein 2550098 7113764 Mchl_2408 Methylobacterium extorquens CM4 hypothetical protein YP_002421179.1 2548800 D 440085 CDS YP_002421180.1 218530364 7113765 2550135..2551397 1 NC_011757.1 PFAM: glycosyl transferase family 28; KEGG: mex:Mext_2132 glycosyl transferase; glycosyl transferase family protein 2551397 7113765 Mchl_2409 Methylobacterium extorquens CM4 glycosyl transferase family protein YP_002421180.1 2550135 D 440085 CDS YP_002421181.1 218530365 7113766 complement(2551404..2552180) 1 NC_011757.1 PFAM: creatininase; KEGG: mex:Mext_2133 creatininase; creatininase 2552180 7113766 Mchl_2410 Methylobacterium extorquens CM4 creatininase YP_002421181.1 2551404 R 440085 CDS YP_002421182.1 218530366 7113767 2552329..2553270 1 NC_011757.1 KEGG: mex:Mext_2134 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor-containing diguanylate cyclase 2553270 7113767 Mchl_2411 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase YP_002421182.1 2552329 D 440085 CDS YP_002421183.1 218530367 7113768 complement(2553254..2553670) 1 NC_011757.1 KEGG: mex:Mext_2135 hypothetical protein; hypothetical protein 2553670 7113768 Mchl_2412 Methylobacterium extorquens CM4 hypothetical protein YP_002421183.1 2553254 R 440085 CDS YP_002421184.1 218530368 7113769 complement(2553799..2554002) 1 NC_011757.1 PFAM: CsbD family protein; KEGG: mex:Mext_2136 CsbD family protein; CsbD family protein 2554002 7113769 Mchl_2413 Methylobacterium extorquens CM4 CsbD family protein YP_002421184.1 2553799 R 440085 CDS YP_002421185.1 218530369 7113770 2554307..2555617 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_2137 major facilitator transporter; major facilitator superfamily protein 2555617 7113770 Mchl_2414 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421185.1 2554307 D 440085 CDS YP_002421186.1 218530370 7113771 2555629..2556393 1 NC_011757.1 PFAM: fumarylacetoacetate hydrolase; KEGG: mex:Mext_2138 fumarylacetoacetate hydrolase; fumarylacetoacetate hydrolase 2556393 7113771 Mchl_2415 Methylobacterium extorquens CM4 fumarylacetoacetate hydrolase YP_002421186.1 2555629 D 440085 CDS YP_002421187.1 218530371 7113772 2556499..2557506 1 NC_011757.1 KEGG: mex:Mext_2139 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; ketopantoate reductase; 2-dehydropantoate 2-reductase 2557506 7113772 Mchl_2416 Methylobacterium extorquens CM4 2-dehydropantoate 2-reductase YP_002421187.1 2556499 D 440085 CDS YP_002421188.1 218530372 7113773 2557509..2559089 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_2140 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 2559089 7113773 Mchl_2417 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002421188.1 2557509 D 440085 CDS YP_002421189.1 218530373 7113774 complement(2559225..2559506) 1 NC_011757.1 KEGG: mex:Mext_2141 hypothetical protein; hypothetical protein 2559506 7113774 Mchl_2418 Methylobacterium extorquens CM4 hypothetical protein YP_002421189.1 2559225 R 440085 CDS YP_002421190.1 218530374 7113775 complement(2559507..2559761) 1 NC_011757.1 KEGG: mex:Mext_2142 hypothetical protein; hypothetical protein 2559761 7113775 Mchl_2419 Methylobacterium extorquens CM4 hypothetical protein YP_002421190.1 2559507 R 440085 CDS YP_002421191.1 218530375 7113776 complement(2559877..2560242) 1 NC_011757.1 KEGG: mex:Mext_2143 hypothetical protein; hypothetical protein 2560242 7113776 Mchl_2420 Methylobacterium extorquens CM4 hypothetical protein YP_002421191.1 2559877 R 440085 CDS YP_002421192.1 218530376 7113777 complement(2560373..2561575) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_2144 major facilitator transporter; major facilitator superfamily protein 2561575 7113777 Mchl_2421 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421192.1 2560373 R 440085 CDS YP_002421193.1 218530377 7113778 2561693..2562595 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_2145 LysR substrate-binding; LysR family transcriptional regulator 2562595 7113778 Mchl_2422 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002421193.1 2561693 D 440085 CDS YP_002421194.1 218530378 7113779 complement(2562579..2562968) 1 NC_011757.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: mex:Mext_2146 4-oxalocrotonate tautomerase; 4-oxalocrotonate tautomerase 2562968 7113779 Mchl_2423 Methylobacterium extorquens CM4 4-oxalocrotonate tautomerase YP_002421194.1 2562579 R 440085 CDS YP_002421195.1 218530379 7113780 2563229..2564119 1 NC_011757.1 PFAM: HpcH/HpaI aldolase; KEGG: mex:Mext_2147 citrate (pro-3S)-lyase; Citryl-CoA lyase 2564119 7113780 Mchl_2424 Methylobacterium extorquens CM4 Citryl-CoA lyase YP_002421195.1 2563229 D 440085 CDS YP_002421196.1 218530380 7113781 complement(2564189..2564578) 1 NC_011757.1 KEGG: mex:Mext_2148 hypothetical protein; hypothetical protein 2564578 7113781 Mchl_2425 Methylobacterium extorquens CM4 hypothetical protein YP_002421196.1 2564189 R 440085 CDS YP_002421197.1 218530381 7113782 complement(2564804..2565478) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_2149 HAD family hydrolase; HAD-superfamily hydrolase 2565478 7113782 Mchl_2426 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002421197.1 2564804 R 440085 CDS YP_002421198.1 218530382 7113783 2565631..2567043 1 NC_011757.1 KEGG: mex:Mext_2150 hypothetical protein; hypothetical protein 2567043 7113783 Mchl_2427 Methylobacterium extorquens CM4 hypothetical protein YP_002421198.1 2565631 D 440085 CDS YP_002421199.1 218530383 7113784 2567056..2567691 1 NC_011757.1 KEGG: mex:Mext_2151 hypothetical protein; hypothetical protein 2567691 7113784 Mchl_2428 Methylobacterium extorquens CM4 hypothetical protein YP_002421199.1 2567056 D 440085 CDS YP_002421200.1 218530384 7113785 complement(2567790..2568731) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_2152 LysR substrate-binding; LysR family transcriptional regulator 2568731 7113785 Mchl_2429 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002421200.1 2567790 R 440085 CDS YP_002421201.1 218530385 7113786 2568866..2569795 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_2153 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2569795 7113786 Mchl_2430 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002421201.1 2568866 D 440085 CDS YP_002421202.1 218530386 7113787 2569872..2570501 1 NC_011757.1 PFAM: phospholipase/carboxylesterase; KEGG: mex:Mext_2154 phospholipase/carboxylesterase; phospholipase/carboxylesterase 2570501 7113787 Mchl_2431 Methylobacterium extorquens CM4 phospholipase/carboxylesterase YP_002421202.1 2569872 D 440085 CDS YP_002421203.1 218530387 7113789 2571093..2571320 1 NC_011757.1 KEGG: mex:Mext_2155 hypothetical protein; hypothetical protein 2571320 7113789 Mchl_2433 Methylobacterium extorquens CM4 hypothetical protein YP_002421203.1 2571093 D 440085 CDS YP_002421204.1 218530388 7113790 2571869..2575348 1 NC_011757.1 KEGG: mex:Mext_2156 hypothetical protein; hypothetical protein 2575348 7113790 Mchl_2434 Methylobacterium extorquens CM4 hypothetical protein YP_002421204.1 2571869 D 440085 CDS YP_002421205.1 218530389 7113791 2575737..2576108 1 NC_011757.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2576108 rpsL 7113791 rpsL Methylobacterium extorquens CM4 30S ribosomal protein S12 YP_002421205.1 2575737 D 440085 CDS YP_002421206.1 218530390 7113792 2576215..2576685 1 NC_011757.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2576685 7113792 Mchl_2436 Methylobacterium extorquens CM4 30S ribosomal protein S7 YP_002421206.1 2576215 D 440085 CDS YP_002421207.1 218530391 7113793 2576749..2578824 1 NC_011757.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2578824 7113793 Mchl_2437 Methylobacterium extorquens CM4 elongation factor G YP_002421207.1 2576749 D 440085 CDS YP_002421208.1 218530392 7113794 2578878..2580068 1 NC_011757.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 2580068 7113794 Mchl_2438 Methylobacterium extorquens CM4 elongation factor Tu YP_002421208.1 2578878 D 440085 CDS YP_002421209.1 218530393 7113795 2580148..2580456 1 NC_011757.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2580456 rpsJ 7113795 rpsJ Methylobacterium extorquens CM4 30S ribosomal protein S10 YP_002421209.1 2580148 D 440085 CDS YP_002421210.1 218530394 7113796 2580507..2581247 1 NC_011757.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2581247 rplC 7113796 rplC Methylobacterium extorquens CM4 50S ribosomal protein L3 YP_002421210.1 2580507 D 440085 CDS YP_002421211.1 218530395 7113797 2581247..2581867 1 NC_011757.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2581867 rplD 7113797 rplD Methylobacterium extorquens CM4 50S ribosomal protein L4 YP_002421211.1 2581247 D 440085 CDS YP_002421212.1 218530396 7113798 2581864..2582160 1 NC_011757.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2582160 rplW 7113798 rplW Methylobacterium extorquens CM4 50S ribosomal protein L23 YP_002421212.1 2581864 D 440085 CDS YP_002421213.1 218530397 7113799 2582186..2583022 1 NC_011757.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2583022 rplB 7113799 rplB Methylobacterium extorquens CM4 50S ribosomal protein L2 YP_002421213.1 2582186 D 440085 CDS YP_002421214.1 218530398 7113800 2583028..2583306 1 NC_011757.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2583306 rpsS 7113800 rpsS Methylobacterium extorquens CM4 30S ribosomal protein S19 YP_002421214.1 2583028 D 440085 CDS YP_002421215.1 218530399 7113801 2583308..2583691 1 NC_011757.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2583691 rplV 7113801 rplV Methylobacterium extorquens CM4 50S ribosomal protein L22 YP_002421215.1 2583308 D 440085 CDS YP_002421216.1 218530400 7113802 2583703..2584449 1 NC_011757.1 KEGG: mex:Mext_2168 ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; ribosomal protein S3 domain; SMART: KH domain protein; 30S ribosomal protein S3 2584449 7113802 Mchl_2446 Methylobacterium extorquens CM4 30S ribosomal protein S3 YP_002421216.1 2583703 D 440085 CDS YP_002421217.1 218530401 7113803 2584483..2584896 1 NC_011757.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2584896 rplP 7113803 rplP Methylobacterium extorquens CM4 50S ribosomal protein L16 YP_002421217.1 2584483 D 440085 CDS YP_002421218.1 218530402 7113804 2584909..2585124 1 NC_011757.1 PFAM: ribosomal protein L29; KEGG: mpo:Mpop_2131 ribosomal protein L29; 50S ribosomal protein L29 2585124 7113804 Mchl_2448 Methylobacterium extorquens CM4 50S ribosomal protein L29 YP_002421218.1 2584909 D 440085 CDS YP_002421219.1 218530403 7113805 2585136..2585402 1 NC_011757.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2585402 rpsQ 7113805 rpsQ Methylobacterium extorquens CM4 30S ribosomal protein S17 YP_002421219.1 2585136 D 440085 CDS YP_002421220.1 218530404 7113806 2585814..2587202 1 NC_011757.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: mex:Mext_2172 ATPase central domain-containing protein; ATPase AAA 2587202 7113806 Mchl_2450 Methylobacterium extorquens CM4 ATPase AAA YP_002421220.1 2585814 D 440085 CDS YP_002421221.1 218530405 7113807 complement(2587414..2587872) 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_2173 NUDIX hydrolase; NUDIX hydrolase 2587872 7113807 Mchl_2451 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002421221.1 2587414 R 440085 CDS YP_002421222.1 218530406 7113808 complement(2588118..2588582) 1 NC_011757.1 PFAM: regulatory protein MarR; transcriptional regulator PadR family protein; KEGG: mex:Mext_2174 regulatory protein MarR; MarR family transcriptional regulator 2588582 7113808 Mchl_2452 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002421222.1 2588118 R 440085 CDS YP_002421223.1 218530407 7113809 complement(2588872..2589288) 1 NC_011757.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2589288 rplQ 7113809 rplQ Methylobacterium extorquens CM4 50S ribosomal protein L17 YP_002421223.1 2588872 R 440085 CDS YP_002421224.1 218530408 7113810 complement(2589523..2590542) 1 NC_011757.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2590542 7113810 Mchl_2454 Methylobacterium extorquens CM4 DNA-directed RNA polymerase subunit alpha YP_002421224.1 2589523 R 440085 CDS YP_002421225.1 218530409 7113811 complement(2590641..2591522) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_2177 beta-lactamase domain-containing protein; beta-lactamase 2591522 7113811 Mchl_2455 Methylobacterium extorquens CM4 beta-lactamase YP_002421225.1 2590641 R 440085 CDS YP_002421226.1 218530410 7113812 complement(2591560..2591949) 1 NC_011757.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2591949 7113812 Mchl_2456 Methylobacterium extorquens CM4 30S ribosomal protein S11 YP_002421226.1 2591560 R 440085 CDS YP_002421227.1 218530411 7113813 complement(2592120..2592488) 1 NC_011757.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2592488 rpsM 7113813 rpsM Methylobacterium extorquens CM4 30S ribosomal protein S13 YP_002421227.1 2592120 R 440085 CDS YP_002421228.1 218530412 7113814 complement(2592792..2593394) 1 NC_011757.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2593394 adk 7113814 adk Methylobacterium extorquens CM4 adenylate kinase YP_002421228.1 2592792 R 440085 CDS YP_002421229.1 218530413 7113815 complement(2593565..2594908) 1 NC_011757.1 TIGRFAM: preprotein translocase, SecY subunit; PFAM: SecY protein; KEGG: mex:Mext_2181 preprotein translocase, SecY subunit; preprotein translocase subunit SecY 2594908 7113815 Mchl_2459 Methylobacterium extorquens CM4 preprotein translocase subunit SecY YP_002421229.1 2593565 R 440085 CDS YP_002421230.1 218530414 7113816 complement(2595023..2595532) 1 NC_011757.1 late assembly protein; 50S ribosomal protein L15 2595532 rplO 7113816 rplO Methylobacterium extorquens CM4 50S ribosomal protein L15 YP_002421230.1 2595023 R 440085 CDS YP_002421231.1 218530415 7114362 complement(2595546..2595740) 1 NC_011757.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2595740 rpmD 7114362 rpmD Methylobacterium extorquens CM4 50S ribosomal protein L30 YP_002421231.1 2595546 R 440085 CDS YP_002421232.1 218530416 7114447 complement(2595752..2596330) 1 NC_011757.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2596330 rpsE 7114447 rpsE Methylobacterium extorquens CM4 30S ribosomal protein S5 YP_002421232.1 2595752 R 440085 CDS YP_002421233.1 218530417 7114448 complement(2596421..2596783) 1 NC_011757.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2596783 rplR 7114448 rplR Methylobacterium extorquens CM4 50S ribosomal protein L18 YP_002421233.1 2596421 R 440085 CDS YP_002421234.1 218530418 7114449 complement(2596795..2597328) 1 NC_011757.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2597328 rplF 7114449 rplF Methylobacterium extorquens CM4 50S ribosomal protein L6 YP_002421234.1 2596795 R 440085 CDS YP_002421235.1 218530419 7114450 complement(2597345..2597740) 1 NC_011757.1 PFAM: ribosomal protein S8; KEGG: mex:Mext_2187 ribosomal protein S8; 30S ribosomal protein S8 2597740 7114450 Mchl_2465 Methylobacterium extorquens CM4 30S ribosomal protein S8 YP_002421235.1 2597345 R 440085 CDS YP_002421236.1 218530420 7114451 complement(2597753..2598058) 1 NC_011757.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2598058 rpsN 7114451 rpsN Methylobacterium extorquens CM4 30S ribosomal protein S14 YP_002421236.1 2597753 R 440085 CDS YP_002421237.1 218530421 7114452 complement(2598100..2598666) 1 NC_011757.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2598666 7114452 Mchl_2467 Methylobacterium extorquens CM4 50S ribosomal protein L5 YP_002421237.1 2598100 R 440085 CDS YP_002421238.1 218530422 7114453 complement(2598659..2598973) 1 NC_011757.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2598973 rplX 7114453 rplX Methylobacterium extorquens CM4 50S ribosomal protein L24 YP_002421238.1 2598659 R 440085 CDS YP_002421239.1 218530423 7114454 complement(2598973..2599332) 1 NC_011757.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2599332 rplN 7114454 rplN Methylobacterium extorquens CM4 50S ribosomal protein L14 YP_002421239.1 2598973 R 440085 CDS YP_002421240.1 218530424 7114455 complement(2599695..2599976) 1 NC_011757.1 KEGG: mex:Mext_2192 hypothetical protein; hypothetical protein 2599976 7114455 Mchl_2470 Methylobacterium extorquens CM4 hypothetical protein YP_002421240.1 2599695 R 440085 CDS YP_002421241.1 218530425 7114456 complement(2600285..2600818) 1 NC_011757.1 PFAM: nuclease (SNase domain protein); KEGG: mex:Mext_2193 nuclease; nuclease 2600818 7114456 Mchl_2471 Methylobacterium extorquens CM4 nuclease YP_002421241.1 2600285 R 440085 CDS YP_002421242.1 218530426 7114457 2601421..2601801 1 NC_011757.1 KEGG: mex:Mext_2194 hypothetical protein; hypothetical protein 2601801 7114457 Mchl_2472 Methylobacterium extorquens CM4 hypothetical protein YP_002421242.1 2601421 D 440085 CDS YP_002421243.1 218530427 7114458 2601915..2603162 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_2195 diguanylate cyclase; diguanylate cyclase 2603162 7114458 Mchl_2473 Methylobacterium extorquens CM4 diguanylate cyclase YP_002421243.1 2601915 D 440085 CDS YP_002421244.1 218530428 7114459 2603253..2604323 1 NC_011757.1 KEGG: mex:Mext_2196 hypothetical protein; hypothetical protein 2604323 7114459 Mchl_2474 Methylobacterium extorquens CM4 hypothetical protein YP_002421244.1 2603253 D 440085 CDS YP_002421245.1 218530429 7114460 complement(2604388..2604900) 1 NC_011757.1 KEGG: mex:Mext_2197 hypothetical protein; hypothetical protein 2604900 7114460 Mchl_2475 Methylobacterium extorquens CM4 hypothetical protein YP_002421245.1 2604388 R 440085 CDS YP_002421246.1 218530430 7114461 complement(2605058..2605186) 1 NC_011757.1 KEGG: mex:Mext_2198 hypothetical protein; hypothetical protein 2605186 7114461 Mchl_2476 Methylobacterium extorquens CM4 hypothetical protein YP_002421246.1 2605058 R 440085 CDS YP_002421247.1 218530431 7114462 complement(2605235..2605531) 1 NC_011757.1 KEGG: mex:Mext_2199 hypothetical protein; hypothetical protein 2605531 7114462 Mchl_2477 Methylobacterium extorquens CM4 hypothetical protein YP_002421247.1 2605235 R 440085 CDS YP_002421248.1 218530432 7114463 2605815..2606072 1 NC_011757.1 KEGG: mex:Mext_2200 hypothetical protein; hypothetical protein 2606072 7114463 Mchl_2478 Methylobacterium extorquens CM4 hypothetical protein YP_002421248.1 2605815 D 440085 CDS YP_002421249.1 218530433 7114464 2606329..2606598 1 NC_011757.1 KEGG: mex:Mext_2202 hypothetical protein; hypothetical protein 2606598 7114464 Mchl_2479 Methylobacterium extorquens CM4 hypothetical protein YP_002421249.1 2606329 D 440085 CDS YP_002421250.1 218530434 7114466 complement(2606945..2608132) 1 NC_011757.1 PFAM: monooxygenase FAD-binding; KEGG: mex:Mext_2203 monooxygenase FAD-binding; FAD-binding monooxygenase 2608132 7114466 Mchl_2480 Methylobacterium extorquens CM4 FAD-binding monooxygenase YP_002421250.1 2606945 R 440085 CDS YP_002421251.1 218530435 7114467 complement(2608149..2608415) 1 NC_011757.1 KEGG: mex:Mext_2204 hypothetical protein; hypothetical protein 2608415 7114467 Mchl_2481 Methylobacterium extorquens CM4 hypothetical protein YP_002421251.1 2608149 R 440085 CDS YP_002421252.1 218530436 7114468 2608632..2609486 1 NC_011757.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: mex:Mext_2206 methionine aminopeptidase, type I; methionine aminopeptidase, type I 2609486 7114468 Mchl_2482 Methylobacterium extorquens CM4 methionine aminopeptidase, type I YP_002421252.1 2608632 D 440085 CDS YP_002421253.1 218530437 7114469 2609501..2610247 1 NC_011757.1 PFAM: DNA repair protein RadC; KEGG: mex:Mext_2207 DNA repair protein RadC; DNA repair protein RadC 2610247 7114469 Mchl_2483 Methylobacterium extorquens CM4 DNA repair protein RadC YP_002421253.1 2609501 D 440085 CDS YP_002421254.1 218530438 7114470 2610563..2612002 1 NC_011757.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: mex:Mext_2208 hypothetical protein; hypothetical protein 2612002 7114470 Mchl_2484 Methylobacterium extorquens CM4 hypothetical protein YP_002421254.1 2610563 D 440085 CDS YP_002421255.1 218530439 7114471 2612110..2613054 1 NC_011757.1 PFAM: protein of unknown function DUF403; KEGG: mex:Mext_2209 hypothetical protein; hypothetical protein 2613054 7114471 Mchl_2485 Methylobacterium extorquens CM4 hypothetical protein YP_002421255.1 2612110 D 440085 CDS YP_002421256.1 218530440 7114472 complement(2613155..2613409) 1 NC_011757.1 KEGG: mex:Mext_2210 hypothetical protein; hypothetical protein 2613409 7114472 Mchl_2486 Methylobacterium extorquens CM4 hypothetical protein YP_002421256.1 2613155 R 440085 CDS YP_002421257.1 218530441 7114473 complement(2613450..2613899) 1 NC_011757.1 KEGG: mex:Mext_2211 hypothetical protein; hypothetical protein 2613899 7114473 Mchl_2487 Methylobacterium extorquens CM4 hypothetical protein YP_002421257.1 2613450 R 440085 CDS YP_002421258.1 218530442 7114474 complement(2613907..2614284) 1 NC_011757.1 KEGG: mpo:Mpop_2169 hypothetical protein; hypothetical protein 2614284 7114474 Mchl_2488 Methylobacterium extorquens CM4 hypothetical protein YP_002421258.1 2613907 R 440085 CDS YP_002421259.1 218530443 7114475 complement(2614438..2614842) 1 NC_011757.1 KEGG: mex:Mext_2213 hypothetical protein; hypothetical protein 2614842 7114475 Mchl_2489 Methylobacterium extorquens CM4 hypothetical protein YP_002421259.1 2614438 R 440085 CDS YP_002421260.1 218530444 7114476 2615369..2616259 1 NC_011757.1 PFAM: transglutaminase; transglutaminase domain protein; KEGG: mex:Mext_2214 transglutaminase domain-containing protein; transglutaminase 2616259 7114476 Mchl_2490 Methylobacterium extorquens CM4 transglutaminase YP_002421260.1 2615369 D 440085 CDS YP_002421261.1 218530445 7114477 2616383..2617129 1 NC_011757.1 KEGG: mex:Mext_2215 proteasome-type protease; proteasome-type protease 2617129 7114477 Mchl_2491 Methylobacterium extorquens CM4 proteasome-type protease YP_002421261.1 2616383 D 440085 CDS YP_002421262.1 218530446 7114478 complement(2617244..2617951) 1 NC_011757.1 PFAM: silent information regulator protein Sir2; KEGG: mex:Mext_2216 silent information regulator protein Sir2; silent information regulator protein Sir2 2617951 7114478 Mchl_2492 Methylobacterium extorquens CM4 silent information regulator protein Sir2 YP_002421262.1 2617244 R 440085 CDS YP_002421263.1 218530447 7114479 complement(2617960..2619174) 1 NC_011757.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: mpo:Mpop_2174 protein of unknown function DUF21; hypothetical protein 2619174 7114479 Mchl_2493 Methylobacterium extorquens CM4 hypothetical protein YP_002421263.1 2617960 R 440085 CDS YP_002421264.1 218530448 7114480 2619541..2622720 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_2218 glycosyl transferase; family 2 glycosyl transferase 2622720 7114480 Mchl_2494 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002421264.1 2619541 D 440085 CDS YP_002421265.1 218530449 7114481 2622812..2623042 1 NC_011757.1 KEGG: mex:Mext_2219 hypothetical protein; hypothetical protein 2623042 7114481 Mchl_2495 Methylobacterium extorquens CM4 hypothetical protein YP_002421265.1 2622812 D 440085 CDS YP_002421266.1 218530450 7114482 complement(2623165..2623416) 1 NC_011757.1 KEGG: mex:Mext_2220 hypothetical protein; hypothetical protein 2623416 7114482 Mchl_2496 Methylobacterium extorquens CM4 hypothetical protein YP_002421266.1 2623165 R 440085 CDS YP_002421267.1 218530451 7114483 complement(2623700..2625166) 1 NC_011757.1 KEGG: mex:Mext_2221 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 2625166 7114483 Mchl_2497 Methylobacterium extorquens CM4 protease Do YP_002421267.1 2623700 R 440085 CDS YP_002421268.1 218530452 7114484 complement(2625511..2626263) 1 NC_011757.1 KEGG: mex:Mext_2222 hypothetical protein; hypothetical protein 2626263 7114484 Mchl_2498 Methylobacterium extorquens CM4 hypothetical protein YP_002421268.1 2625511 R 440085 CDS YP_002421269.1 218530453 7114485 complement(2626428..2626784) 1 NC_011757.1 TIGRFAM: phasin; KEGG: mex:Mext_2223 phasin; phasin 2626784 7114485 Mchl_2499 Methylobacterium extorquens CM4 phasin YP_002421269.1 2626428 R 440085 CDS YP_002421270.1 218530454 7114486 complement(2627013..2628317) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_2224 glycosyl transferase group 1; group 1 glycosyl transferase 2628317 7114486 Mchl_2500 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002421270.1 2627013 R 440085 CDS YP_002421271.1 218530455 7114487 2628532..2629803 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_2225 glycosyl transferase group 1; group 1 glycosyl transferase 2629803 7114487 Mchl_2501 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002421271.1 2628532 D 440085 CDS YP_002421272.1 218530456 7114488 2629891..2630070 1 NC_011757.1 KEGG: mex:Mext_2226 hypothetical protein; hypothetical protein 2630070 7114488 Mchl_2502 Methylobacterium extorquens CM4 hypothetical protein YP_002421272.1 2629891 D 440085 CDS YP_002421273.1 218530457 7114489 complement(2630105..2632522) 1 NC_011757.1 KEGG: mex:Mext_2227 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 2632522 7114489 Mchl_2503 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_002421273.1 2630105 R 440085 CDS YP_002421274.1 218530458 7114490 complement(2632669..2634357) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_2228 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 2634357 7114490 Mchl_2504 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002421274.1 2632669 R 440085 CDS YP_002421275.1 218530459 7114491 complement(2634520..2635443) 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_2229 hypothetical protein; hypothetical protein 2635443 7114491 Mchl_2505 Methylobacterium extorquens CM4 hypothetical protein YP_002421275.1 2634520 R 440085 CDS YP_002421276.1 218530460 7114492 2635518..2636465 1 NC_011757.1 PFAM: ribonuclease BN; KEGG: mex:Mext_2230 ribonuclease BN; ribonuclease BN 2636465 7114492 Mchl_2506 Methylobacterium extorquens CM4 ribonuclease BN YP_002421276.1 2635518 D 440085 CDS YP_002421277.1 218530461 7114493 complement(2636377..2637417) 1 NC_011757.1 KEGG: mex:Mext_2231 hypothetical protein; hypothetical protein 2637417 7114493 Mchl_2507 Methylobacterium extorquens CM4 hypothetical protein YP_002421277.1 2636377 R 440085 CDS YP_002421278.1 218530462 7114494 complement(2637604..2639013) 1 NC_011757.1 KEGG: mex:Mext_2232 sulfate adenylyltransferase, large subunit; TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; sulfate adenylyltransferase, large subunit 2639013 7114494 Mchl_2508 Methylobacterium extorquens CM4 sulfate adenylyltransferase, large subunit YP_002421278.1 2637604 R 440085 CDS YP_002421279.1 218530463 7114495 complement(2639013..2639942) 1 NC_011757.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2639942 7114495 Mchl_2509 Methylobacterium extorquens CM4 sulfate adenylyltransferase subunit 2 YP_002421279.1 2639013 R 440085 CDS YP_002421280.1 218530464 7114496 complement(2639942..2640751) 1 NC_011757.1 KEGG: mex:Mext_2234 adenylylsulfate reductase, thioredoxin dependent; TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; PFAM: phosphoadenosine phosphosulfate reductase; adenylylsulfate reductase, thioredoxin dependent 2640751 7114496 Mchl_2510 Methylobacterium extorquens CM4 adenylylsulfate reductase, thioredoxin dependent YP_002421280.1 2639942 R 440085 CDS YP_002421281.1 218530465 7114497 2641016..2641519 1 NC_011757.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: mex:Mext_2235 AsnC/Lrp family regulatory protein; AsnC family transcriptional regulator 2641519 7114497 Mchl_2511 Methylobacterium extorquens CM4 AsnC family transcriptional regulator YP_002421281.1 2641016 D 440085 CDS YP_002421282.1 218530466 7114498 2641620..2643407 1 NC_011757.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: mex:Mext_2236 flavodoxin/nitric oxide synthase; flavodoxin/nitric oxide synthase 2643407 7114498 Mchl_2512 Methylobacterium extorquens CM4 flavodoxin/nitric oxide synthase YP_002421282.1 2641620 D 440085 CDS YP_002421283.1 218530467 7114499 2643601..2645439 1 NC_011757.1 hemoprotein; NADPH dependent; with the subunit alpha (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 2645439 7114499 Mchl_2513 Methylobacterium extorquens CM4 sulfite reductase subunit beta YP_002421283.1 2643601 D 440085 CDS YP_002421284.1 218530468 7114500 complement(2645503..2647683) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2239 TonB-dependent receptor plug; TonB-dependent siderophore receptor 2647683 7114500 Mchl_2514 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002421284.1 2645503 R 440085 CDS YP_002421285.1 218530469 7114501 complement(2648016..2648873) 1 NC_011757.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 2648873 panC 7114501 panC Methylobacterium extorquens CM4 pantoate--beta-alanine ligase YP_002421285.1 2648016 R 440085 CDS YP_002421286.1 218530470 7114502 complement(2648948..2649307) 1 NC_011757.1 KEGG: mex:Mext_2241 hypothetical protein; hypothetical protein 2649307 7114502 Mchl_2516 Methylobacterium extorquens CM4 hypothetical protein YP_002421286.1 2648948 R 440085 CDS YP_002421287.1 218530471 7114503 complement(2649380..2649985) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: mex:Mext_2242 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 2649985 7114503 Mchl_2517 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002421287.1 2649380 R 440085 CDS YP_002421288.1 218530472 7114504 complement(2650362..2650931) 1 NC_011757.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: mex:Mext_2243 single-strand binding protein; single-strand binding protein 2650931 7114504 Mchl_2518 Methylobacterium extorquens CM4 single-strand binding protein YP_002421288.1 2650362 R 440085 CDS YP_002421289.1 218530473 7114505 complement(2651166..2652182) 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: mex:Mext_2244 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 2652182 7114505 Mchl_2519 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002421289.1 2651166 R 440085 CDS YP_002421290.1 218530474 7114506 2652275..2652682 1 NC_011757.1 KEGG: mex:Mext_2245 hypothetical protein; hypothetical protein 2652682 7114506 Mchl_2520 Methylobacterium extorquens CM4 hypothetical protein YP_002421290.1 2652275 D 440085 CDS YP_002421291.1 218530475 7114507 complement(2652735..2653301) 1 NC_011757.1 KEGG: mex:Mext_2246 hypothetical protein; hypothetical protein 2653301 7114507 Mchl_2521 Methylobacterium extorquens CM4 hypothetical protein YP_002421291.1 2652735 R 440085 CDS YP_002421292.1 218530476 7114508 2653531..2654304 1 NC_011757.1 KEGG: mex:Mext_2247 hypothetical protein; hypothetical protein 2654304 7114508 Mchl_2522 Methylobacterium extorquens CM4 hypothetical protein YP_002421292.1 2653531 D 440085 CDS YP_002421293.1 218530477 7114509 complement(2654470..2655588) 1 NC_011757.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: mex:Mext_2248 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 2655588 7114509 Mchl_2523 Methylobacterium extorquens CM4 NADH:flavin oxidoreductase/NADH oxidase YP_002421293.1 2654470 R 440085 CDS YP_002421294.1 218530478 7114510 2655758..2656747 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_2249 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 2656747 7114510 Mchl_2524 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002421294.1 2655758 D 440085 CDS YP_002421295.1 218530479 7114511 2656819..2657334 1 NC_011757.1 KEGG: mex:Mext_2250 hypothetical protein; hypothetical protein 2657334 7114511 Mchl_2525 Methylobacterium extorquens CM4 hypothetical protein YP_002421295.1 2656819 D 440085 CDS YP_002421296.1 218530480 7114512 2657570..2658478 1 NC_011757.1 PFAM: thioredoxin domain; KEGG: mex:Mext_2251 thioredoxin domain-containing protein; thioredoxin domain 2658478 7114512 Mchl_2526 Methylobacterium extorquens CM4 thioredoxin domain YP_002421296.1 2657570 D 440085 CDS YP_002421297.1 218530481 7114513 2658564..2659232 1 NC_011757.1 PFAM: peptidase S16; KEGG: mex:Mext_2252 peptidase S16 lon domain-containing protein; peptidase S16 2659232 7114513 Mchl_2527 Methylobacterium extorquens CM4 peptidase S16 YP_002421297.1 2658564 D 440085 CDS YP_002421298.1 218530482 7114514 2659290..2659496 1 NC_011757.1 PFAM: protein of unknown function DUF343; KEGG: mex:Mext_2253 hypothetical protein; hypothetical protein 2659496 7114514 Mchl_2528 Methylobacterium extorquens CM4 hypothetical protein YP_002421298.1 2659290 D 440085 CDS YP_002421299.1 218530483 7114515 complement(2659595..2660554) 1 NC_011757.1 PFAM: import inner membrane translocase subunit Tim44; KEGG: mex:Mext_2254 import inner membrane translocase subunit Tim44; import inner membrane translocase subunit Tim44 2660554 7114515 Mchl_2529 Methylobacterium extorquens CM4 import inner membrane translocase subunit Tim44 YP_002421299.1 2659595 R 440085 CDS YP_002421300.1 218530484 7114516 complement(2660755..2661867) 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; KEGG: mex:Mext_2255 PAS sensor protein; PAS/PAC sensor signal transduction histidine kinase 2661867 7114516 Mchl_2530 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002421300.1 2660755 R 440085 CDS YP_002421301.1 218530485 7114517 complement(2661989..2662693) 1 NC_011757.1 PFAM: cysteine peptidase; KEGG: mex:Mext_2256 cysteine peptidase; cysteine peptidase 2662693 7114517 Mchl_2531 Methylobacterium extorquens CM4 cysteine peptidase YP_002421301.1 2661989 R 440085 CDS YP_002421302.1 218530486 7114518 complement(2662900..2663559) 1 NC_011757.1 PFAM: cysteine peptidase; KEGG: mex:Mext_2257 cysteine peptidase; cysteine peptidase 2663559 7114518 Mchl_2532 Methylobacterium extorquens CM4 cysteine peptidase YP_002421302.1 2662900 R 440085 CDS YP_002421303.1 218530487 7114519 complement(2664028..2664651) 1 NC_011757.1 PFAM: type IV pilus assembly PilZ; KEGG: mex:Mext_2258 type IV pilus assembly PilZ; type IV pilus assembly PilZ 2664651 7114519 Mchl_2533 Methylobacterium extorquens CM4 type IV pilus assembly PilZ YP_002421303.1 2664028 R 440085 CDS YP_002421304.1 218530488 7114520 complement(2664860..2665480) 1 NC_011757.1 PFAM: protein of unknown function DUF1457; KEGG: mex:Mext_2259 hypothetical protein; hypothetical protein 2665480 7114520 Mchl_2534 Methylobacterium extorquens CM4 hypothetical protein YP_002421304.1 2664860 R 440085 CDS YP_002421305.1 218530489 7114521 2665721..2666545 1 NC_011757.1 PFAM: rhomboid family protein; KEGG: mex:Mext_2260 rhomboid family protein; rhomboid family protein 2666545 7114521 Mchl_2535 Methylobacterium extorquens CM4 rhomboid family protein YP_002421305.1 2665721 D 440085 CDS YP_002421306.1 218530490 7114522 2666787..2667674 1 NC_011757.1 KEGG: mex:Mext_2261 hypothetical protein; hypothetical protein 2667674 7114522 Mchl_2536 Methylobacterium extorquens CM4 hypothetical protein YP_002421306.1 2666787 D 440085 CDS YP_002421307.1 218530491 7114523 2668034..2668465 1 NC_011757.1 PFAM: CBS domain containing protein; KEGG: mex:Mext_2262 CBS domain-containing protein; signal transduction protein with CBS domains 2668465 7114523 Mchl_2537 Methylobacterium extorquens CM4 signal transduction protein with CBS domains YP_002421307.1 2668034 D 440085 CDS YP_002421308.1 218530492 7114524 complement(2668519..2669577) 1 NC_011757.1 PFAM: patatin; KEGG: mex:Mext_2263 patatin; patatin 2669577 7114524 Mchl_2538 Methylobacterium extorquens CM4 patatin YP_002421308.1 2668519 R 440085 CDS YP_002421309.1 218530493 7114525 complement(2669574..2669996) 1 NC_011757.1 PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: mex:Mext_2264 phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-AMP cyclohydrolase 2669996 7114525 Mchl_2539 Methylobacterium extorquens CM4 phosphoribosyl-AMP cyclohydrolase YP_002421309.1 2669574 R 440085 CDS YP_002421310.1 218530494 7114526 complement(2670016..2670825) 1 NC_011757.1 PFAM: GTP cyclohydrolase I; KEGG: mex:Mext_2265 GTP cyclohydrolase I; GTP cyclohydrolase I 2670825 7114526 Mchl_2540 Methylobacterium extorquens CM4 GTP cyclohydrolase I YP_002421310.1 2670016 R 440085 CDS YP_002421311.1 218530495 7114527 2671049..2671522 1 NC_011757.1 PFAM: nitrogen-fixing NifU domain protein; KEGG: mex:Mext_2266 NifU domain-containing protein; nitrogen-fixing NifU domain-containing protein 2671522 7114527 Mchl_2541 Methylobacterium extorquens CM4 nitrogen-fixing NifU domain-containing protein YP_002421311.1 2671049 D 440085 CDS YP_002421312.1 218530496 7115675 2671567..2671914 1 NC_011757.1 PFAM: protein of unknown function DUF37; KEGG: mex:Mext_2267 hypothetical protein; hypothetical protein 2671914 7115675 Mchl_2542 Methylobacterium extorquens CM4 hypothetical protein YP_002421312.1 2671567 D 440085 CDS YP_002421313.1 218530497 7117290 complement(2672074..2672841) 1 NC_011757.1 PFAM: protein of unknown function UPF0005; KEGG: mpo:Mpop_2225 protein of unknown function UPF0005; hypothetical protein 2672841 7117290 Mchl_2543 Methylobacterium extorquens CM4 hypothetical protein YP_002421313.1 2672074 R 440085 CDS YP_002421314.1 218530498 7117291 complement(2673059..2675641) 1 NC_011757.1 PFAM: protein of unknown function DUF214; KEGG: mex:Mext_2269 hypothetical protein; hypothetical protein 2675641 7117291 Mchl_2544 Methylobacterium extorquens CM4 hypothetical protein YP_002421314.1 2673059 R 440085 CDS YP_002421315.1 218530499 7117292 complement(2675754..2677169) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mex:Mext_2270 ATPase domain-containing protein; histidine kinase 2677169 7117292 Mchl_2545 Methylobacterium extorquens CM4 histidine kinase YP_002421315.1 2675754 R 440085 CDS YP_002421316.1 218530500 7117293 2677338..2678087 1 NC_011757.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2678087 7117293 Mchl_2546 Methylobacterium extorquens CM4 pyridoxine 5'-phosphate synthase YP_002421316.1 2677338 D 440085 CDS YP_002421317.1 218530501 7117294 2678084..2678494 1 NC_011757.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2678494 acpS 7117294 acpS Methylobacterium extorquens CM4 4'-phosphopantetheinyl transferase YP_002421317.1 2678084 D 440085 CDS YP_002421318.1 218530502 7117295 2678624..2679430 1 NC_011757.1 KEGG: mex:Mext_2273 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; signal peptidase I 2679430 7117295 Mchl_2548 Methylobacterium extorquens CM4 signal peptidase I YP_002421318.1 2678624 D 440085 CDS YP_002421319.1 218530503 7117296 2679491..2680261 1 NC_011757.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein; KEGG: mex:Mext_2274 ribonuclease III; ribonuclease III 2680261 7117296 Mchl_2549 Methylobacterium extorquens CM4 ribonuclease III YP_002421319.1 2679491 D 440085 CDS YP_002421320.1 218530504 7117297 2680282..2681262 1 NC_011757.1 TIGRFAM: small GTP-binding protein; GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; Miro domain protein; KEGG: mex:Mext_2275 GTP-binding protein Era; GTP-binding protein Era 2681262 7117297 Mchl_2550 Methylobacterium extorquens CM4 GTP-binding protein Era YP_002421320.1 2680282 D 440085 CDS YP_002421321.1 218530505 7117298 2681456..2682382 1 NC_011757.1 PFAM: methyltransferase small; KEGG: mex:Mext_2276 methyltransferase small; methyltransferase small 2682382 7117298 Mchl_2551 Methylobacterium extorquens CM4 methyltransferase small YP_002421321.1 2681456 D 440085 CDS YP_002421322.1 218530506 7117299 2682379..2683107 1 NC_011757.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: mex:Mext_2277 pseudouridine synthase; pseudouridine synthase 2683107 7117299 Mchl_2552 Methylobacterium extorquens CM4 pseudouridine synthase YP_002421322.1 2682379 D 440085 CDS YP_002421323.1 218530507 7117300 complement(2683112..2683735) 1 NC_011757.1 KEGG: mex:Mext_2278 hypothetical protein; hypothetical protein 2683735 7117300 Mchl_2553 Methylobacterium extorquens CM4 hypothetical protein YP_002421323.1 2683112 R 440085 CDS YP_002421324.1 218530508 7117301 2683977..2685155 1 NC_011757.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mex:Mext_2279 Sel1 domain-containing protein; Sel1 domain-containing protein repeat-containing protein 2685155 7117301 Mchl_2554 Methylobacterium extorquens CM4 Sel1 domain-containing protein repeat-containing protein YP_002421324.1 2683977 D 440085 CDS YP_002421325.1 218530509 7117302 2685359..2686150 1 NC_011757.1 KEGG: mex:Mext_2280 hypothetical protein; hypothetical protein 2686150 7117302 Mchl_2555 Methylobacterium extorquens CM4 hypothetical protein YP_002421325.1 2685359 D 440085 CDS YP_002421326.1 218530510 7117303 2686361..2686666 1 NC_011757.1 KEGG: mex:Mext_2281 hypothetical protein; hypothetical protein 2686666 7117303 Mchl_2556 Methylobacterium extorquens CM4 hypothetical protein YP_002421326.1 2686361 D 440085 CDS YP_002421327.1 218530511 7117304 complement(2686674..2688602) 1 NC_011757.1 PFAM: K potassium transporter; KEGG: mex:Mext_2282 K potassium transporter; K potassium transporter 2688602 7117304 Mchl_2557 Methylobacterium extorquens CM4 K potassium transporter YP_002421327.1 2686674 R 440085 CDS YP_002421328.1 218530512 7117305 complement(2688802..2689458) 1 NC_011757.1 KEGG: mex:Mext_2283 hypothetical protein; hypothetical protein 2689458 7117305 Mchl_2558 Methylobacterium extorquens CM4 hypothetical protein YP_002421328.1 2688802 R 440085 CDS YP_002421329.1 218530513 7117306 complement(2689486..2690073) 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_2284 NUDIX hydrolase; NUDIX hydrolase 2690073 7117306 Mchl_2559 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002421329.1 2689486 R 440085 CDS YP_002421330.1 218530514 7117307 complement(2690219..2691907) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_2285 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2691907 7117307 Mchl_2560 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421330.1 2690219 R 440085 CDS YP_002421331.1 218530515 7117308 complement(2692254..2693459) 1 NC_011757.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: mex:Mext_2286 protein of unknown function DUF610 YibQ; hypothetical protein 2693459 7117308 Mchl_2561 Methylobacterium extorquens CM4 hypothetical protein YP_002421331.1 2692254 R 440085 CDS YP_002421332.1 218530516 7117309 complement(2693611..2694933) 1 NC_011757.1 KEGG: mex:Mext_2287 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; carboxyl-terminal protease 2694933 7117309 Mchl_2562 Methylobacterium extorquens CM4 carboxyl-terminal protease YP_002421332.1 2693611 R 440085 CDS YP_002421333.1 218530517 7117310 complement(2694933..2696333) 1 NC_011757.1 PFAM: peptidase M23; KEGG: mex:Mext_2288 peptidase M23B; peptidase M23 2696333 7117310 Mchl_2563 Methylobacterium extorquens CM4 peptidase M23 YP_002421333.1 2694933 R 440085 CDS YP_002421334.1 218530518 7117311 complement(2696330..2696827) 1 NC_011757.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2696827 7117311 Mchl_2564 Methylobacterium extorquens CM4 rRNA large subunit methyltransferase YP_002421334.1 2696330 R 440085 CDS YP_002421335.1 218530519 7117312 2697075..2698385 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: mex:Mext_2290 general substrate transporter; general substrate transporter 2698385 7117312 Mchl_2565 Methylobacterium extorquens CM4 general substrate transporter YP_002421335.1 2697075 D 440085 CDS YP_002421336.1 218530520 7117313 2698666..2700615 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_2291 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 2700615 7117313 Mchl_2566 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002421336.1 2698666 D 440085 CDS YP_002421337.1 218530521 7117314 complement(2700620..2701246) 1 NC_011757.1 PFAM: DSBA oxidoreductase; KEGG: mex:Mext_2292 DsbA oxidoreductase; DSBA oxidoreductase 2701246 7117314 Mchl_2567 Methylobacterium extorquens CM4 DSBA oxidoreductase YP_002421337.1 2700620 R 440085 CDS YP_002421338.1 218530522 7117315 2701421..2702662 1 NC_011757.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 2702662 7117315 Mchl_2568 Methylobacterium extorquens CM4 argininosuccinate synthase YP_002421338.1 2701421 D 440085 CDS YP_002421339.1 218530523 7117317 complement(2703238..2703903) 1 NC_011757.1 KEGG: mex:Mext_2295 hypothetical protein; hypothetical protein 2703903 7117317 Mchl_2570 Methylobacterium extorquens CM4 hypothetical protein YP_002421339.1 2703238 R 440085 CDS YP_002421340.1 218530524 7117318 complement(2704099..2704800) 1 NC_011757.1 TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase; KEGG: mex:Mext_2296 phosphoglycolate phosphatase; phosphoglycolate phosphatase 2704800 7117318 Mchl_2571 Methylobacterium extorquens CM4 phosphoglycolate phosphatase YP_002421340.1 2704099 R 440085 CDS YP_002421341.1 218530525 7117319 2704984..2705493 1 NC_011757.1 KEGG: mex:Mext_2297 hypothetical protein; hypothetical protein 2705493 7117319 Mchl_2572 Methylobacterium extorquens CM4 hypothetical protein YP_002421341.1 2704984 D 440085 CDS YP_002421342.1 218530526 7117320 2705674..2706384 1 NC_011757.1 KEGG: mex:Mext_2298 ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; PFAM: ribose 5-phosphate isomerase; ribose 5-phosphate isomerase 2706384 7117320 Mchl_2573 Methylobacterium extorquens CM4 ribose 5-phosphate isomerase YP_002421342.1 2705674 D 440085 CDS YP_002421343.1 218530527 7117321 2706426..2707022 1 NC_011757.1 KEGG: mex:Mext_2299 hypothetical protein; hypothetical protein 2707022 7117321 Mchl_2574 Methylobacterium extorquens CM4 hypothetical protein YP_002421343.1 2706426 D 440085 CDS YP_002421344.1 218530528 7117322 2707077..2708363 1 NC_011757.1 PFAM: O-antigen polymerase; KEGG: mex:Mext_2300 O-antigen polymerase; O-antigen polymerase 2708363 7117322 Mchl_2575 Methylobacterium extorquens CM4 O-antigen polymerase YP_002421344.1 2707077 D 440085 CDS YP_002421345.1 218530529 7117323 2708375..2709760 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mex:Mext_2301 pyridine nucleotide-disulphide oxidoreductase dimerisation region; pyridine nucleotide-disulfide oxidoreductase dimerisation region 2709760 7117323 Mchl_2576 Methylobacterium extorquens CM4 pyridine nucleotide-disulfide oxidoreductase dimerisation region YP_002421345.1 2708375 D 440085 CDS YP_002421346.1 218530530 7117324 complement(2709762..2711171) 1 NC_011757.1 KEGG: mex:Mext_2302 TRAP-type uncharacterized transport system periplasmic component-like protein; TRAP-type transporter periplasmic component-like protein 2711171 7117324 Mchl_2577 Methylobacterium extorquens CM4 TRAP-type transporter periplasmic component-like protein YP_002421346.1 2709762 R 440085 CDS YP_002421347.1 218530531 7117325 2711420..2711902 1 NC_011757.1 KEGG: mex:Mext_2303 hypothetical protein; hypothetical protein 2711902 7117325 Mchl_2578 Methylobacterium extorquens CM4 hypothetical protein YP_002421347.1 2711420 D 440085 CDS YP_002421348.1 218530532 7117326 2711988..2712419 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_2304 OsmC family protein; OsmC family protein 2712419 7117326 Mchl_2579 Methylobacterium extorquens CM4 OsmC family protein YP_002421348.1 2711988 D 440085 CDS YP_002421349.1 218530533 7117327 2712526..2713737 1 NC_011757.1 KEGG: mex:Mext_2305 radical SAM domain-containing protein; radical SAM domain-containing protein 2713737 7117327 Mchl_2580 Methylobacterium extorquens CM4 radical SAM domain-containing protein YP_002421349.1 2712526 D 440085 CDS YP_002421350.1 218530534 7117328 2713737..2715194 1 NC_011757.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: mex:Mext_2306 uracil-DNA glycosylase superfamily protein; uracil-DNA glycosylase superfamily protein 2715194 7117328 Mchl_2581 Methylobacterium extorquens CM4 uracil-DNA glycosylase superfamily protein YP_002421350.1 2713737 D 440085 CDS YP_002421351.1 218530535 7117329 2715464..2716636 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_2307 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 2716636 7117329 Mchl_2582 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES domain-containing protein YP_002421351.1 2715464 D 440085 CDS YP_002421352.1 218530536 7117330 2716779..2717363 1 NC_011757.1 KEGG: mex:Mext_2308 hypothetical protein; hypothetical protein 2717363 7117330 Mchl_2583 Methylobacterium extorquens CM4 hypothetical protein YP_002421352.1 2716779 D 440085 CDS YP_002421353.1 218530537 7117331 complement(2717421..2719118) 1 NC_011757.1 KEGG: mex:Mext_2309 hypothetical protein; hypothetical protein 2719118 7117331 Mchl_2584 Methylobacterium extorquens CM4 hypothetical protein YP_002421353.1 2717421 R 440085 CDS YP_002421354.1 218530538 7117332 complement(2719115..2720233) 1 NC_011757.1 KEGG: mex:Mext_2310 hypothetical protein; hypothetical protein 2720233 7117332 Mchl_2585 Methylobacterium extorquens CM4 hypothetical protein YP_002421354.1 2719115 R 440085 CDS YP_002421355.1 218530539 7117333 2720413..2721075 1 NC_011757.1 PFAM: HpcH/HpaI aldolase; KEGG: mex:Mext_2311 HpcH/HpaI aldolase; HpcH/HpaI aldolase 2721075 7117333 Mchl_2586 Methylobacterium extorquens CM4 HpcH/HpaI aldolase YP_002421355.1 2720413 D 440085 CDS YP_002421356.1 218530540 7117334 2721114..2721701 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_2312 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 2721701 7117334 Mchl_2587 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002421356.1 2721114 D 440085 CDS YP_002421357.1 218530541 7117335 2721809..2722114 1 NC_011757.1 KEGG: mex:Mext_2313 hypothetical protein; hypothetical protein 2722114 7117335 Mchl_2588 Methylobacterium extorquens CM4 hypothetical protein YP_002421357.1 2721809 D 440085 CDS YP_002421358.1 218530542 7117336 2722287..2723279 1 NC_011757.1 PFAM: catalase; KEGG: mex:Mext_2314 catalase domain-containing protein; catalase 2723279 7117336 Mchl_2589 Methylobacterium extorquens CM4 catalase YP_002421358.1 2722287 D 440085 CDS YP_002421359.1 218530543 7117337 complement(2723308..2723571) 1 NC_011757.1 KEGG: mex:Mext_2315 hypothetical protein; hypothetical protein 2723571 7117337 Mchl_2590 Methylobacterium extorquens CM4 hypothetical protein YP_002421359.1 2723308 R 440085 CDS YP_002421360.1 218530544 7117338 complement(2723712..2724317) 1 NC_011757.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: mex:Mext_2316 hypothetical protein; flavin reductase domain-containing FMN-binding protein 2724317 7117338 Mchl_2591 Methylobacterium extorquens CM4 flavin reductase domain-containing FMN-binding protein YP_002421360.1 2723712 R 440085 CDS YP_002421361.1 218530545 7117339 complement(2724328..2724915) 1 NC_011757.1 PFAM: nitroreductase; KEGG: mex:Mext_2317 nitroreductase; nitroreductase 2724915 7117339 Mchl_2592 Methylobacterium extorquens CM4 nitroreductase YP_002421361.1 2724328 R 440085 CDS YP_002421362.1 218530546 7117340 2725073..2725993 1 NC_011757.1 KEGG: mex:Mext_2318 hypothetical protein; hypothetical protein 2725993 7117340 Mchl_2593 Methylobacterium extorquens CM4 hypothetical protein YP_002421362.1 2725073 D 440085 CDS YP_002421363.1 218530547 7117341 2725999..2726391 1 NC_011757.1 KEGG: mex:Mext_2319 hypothetical protein; hypothetical protein 2726391 7117341 Mchl_2594 Methylobacterium extorquens CM4 hypothetical protein YP_002421363.1 2725999 D 440085 CDS YP_002421364.1 218530548 7117342 complement(2726596..2726727) 1 NC_011757.1 KEGG: mpo:Mpop_2274 hypothetical protein; hypothetical protein 2726727 7117342 Mchl_2595 Methylobacterium extorquens CM4 hypothetical protein YP_002421364.1 2726596 R 440085 CDS YP_002421365.1 218530549 7117343 2726854..2728248 1 NC_011757.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: mex:Mext_2320 regulatory protein GntR HTH; GntR family transcriptional regulator 2728248 7117343 Mchl_2596 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002421365.1 2726854 D 440085 CDS YP_002421366.1 218530550 7117345 complement(2730621..2732648) 1 NC_011757.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2732648 thrS 7117345 thrS Methylobacterium extorquens CM4 threonyl-tRNA synthetase YP_002421366.1 2730621 R 440085 CDS YP_002421367.1 218530551 7117346 complement(2732973..2733743) 1 NC_011757.1 KEGG: mex:Mext_2322 hypothetical protein; hypothetical protein 2733743 7117346 Mchl_2599 Methylobacterium extorquens CM4 hypothetical protein YP_002421367.1 2732973 R 440085 CDS YP_002421368.1 218530552 7117347 complement(2733722..2734639) 1 NC_011757.1 PFAM: ROK family protein; KEGG: mex:Mext_2323 ROK family protein; ROK family protein 2734639 7117347 Mchl_2600 Methylobacterium extorquens CM4 ROK family protein YP_002421368.1 2733722 R 440085 CDS YP_002421369.1 218530553 7117348 complement(2734647..2736044) 1 NC_011757.1 PFAM: sodium:dicarboxylate symporter; KEGG: mex:Mext_2324 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter 2736044 7117348 Mchl_2601 Methylobacterium extorquens CM4 sodium:dicarboxylate symporter YP_002421369.1 2734647 R 440085 CDS YP_002421370.1 218530554 7117349 2736527..2739502 1 NC_011757.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 2739502 ileS 7117349 ileS Methylobacterium extorquens CM4 isoleucyl-tRNA synthetase YP_002421370.1 2736527 D 440085 CDS YP_002421371.1 218530555 7117350 2739499..2740014 1 NC_011757.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 2740014 7117350 Mchl_2603 Methylobacterium extorquens CM4 lipoprotein signal peptidase YP_002421371.1 2739499 D 440085 CDS YP_002421372.1 218530556 7117351 2740177..2740881 1 NC_011757.1 KEGG: mex:Mext_2327 hypothetical protein; hypothetical protein 2740881 7117351 Mchl_2604 Methylobacterium extorquens CM4 hypothetical protein YP_002421372.1 2740177 D 440085 CDS YP_002421373.1 218530557 7117352 2741074..2742456 1 NC_011757.1 PFAM: peptidase M16 domain protein; KEGG: mex:Mext_2328 peptidase M16 domain-containing protein; peptidase M16 domain-containing protein 2742456 7117352 Mchl_2605 Methylobacterium extorquens CM4 peptidase M16 domain-containing protein YP_002421373.1 2741074 D 440085 CDS YP_002421374.1 218530558 7117353 2742528..2743811 1 NC_011757.1 PFAM: peptidase M16 domain protein; KEGG: mex:Mext_2329 peptidase M16 domain-containing protein; peptidase M16 domain-containing protein 2743811 7117353 Mchl_2606 Methylobacterium extorquens CM4 peptidase M16 domain-containing protein YP_002421374.1 2742528 D 440085 CDS YP_002421375.1 218530559 7117354 2744022..2744225 1 NC_011757.1 PFAM: YcfA family protein; KEGG: nha:Nham_0566 YcfA-like; YcfA family protein 2744225 7117354 Mchl_2607 Methylobacterium extorquens CM4 YcfA family protein YP_002421375.1 2744022 D 440085 CDS YP_002421376.1 218530560 7117355 2744263..2744670 1 NC_011757.1 PFAM: CopG domain protein DNA-binding domain protein; protein of unknown function UPF0150; KEGG: nha:Nham_0567 hypothetical protein; hypothetical protein 2744670 7117355 Mchl_2608 Methylobacterium extorquens CM4 hypothetical protein YP_002421376.1 2744263 D 440085 CDS YP_002421377.1 218530561 7117356 2744753..2745685 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_2330 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2745685 7117356 Mchl_2609 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002421377.1 2744753 D 440085 CDS YP_002421378.1 218530562 7117357 2745855..2746628 1 NC_011757.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: mex:Mext_2331 oxidoreductase FAD/NAD(P)-binding subunit; oxidoreductase FAD/NAD(P)-binding domain-containing protein 2746628 7117357 Mchl_2610 Methylobacterium extorquens CM4 oxidoreductase FAD/NAD(P)-binding domain-containing protein YP_002421378.1 2745855 D 440085 CDS YP_002421379.1 218530563 7117358 2746923..2747600 1 NC_011757.1 TIGRFAM: dethiobiotin synthase; KEGG: mex:Mext_2332 dethiobiotin synthase; dethiobiotin synthase 2747600 7117358 Mchl_2611 Methylobacterium extorquens CM4 dethiobiotin synthase YP_002421379.1 2746923 D 440085 CDS YP_002421380.1 218530564 7117359 complement(2747607..2747966) 1 NC_011757.1 KEGG: mex:Mext_2333 PRC-barrel; PRC-barrel 2747966 7117359 Mchl_2612 Methylobacterium extorquens CM4 PRC-barrel YP_002421380.1 2747607 R 440085 CDS YP_002421381.1 218530565 7117360 complement(2748001..2748420) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_2334 response regulator receiver; response regulator receiver protein 2748420 7117360 Mchl_2613 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421381.1 2748001 R 440085 CDS YP_002421382.1 218530566 7117361 2748688..2749362 1 NC_011757.1 PFAM: protein of unknown function DUF1275; KEGG: mex:Mext_2335 hypothetical protein; hypothetical protein 2749362 7117361 Mchl_2614 Methylobacterium extorquens CM4 hypothetical protein YP_002421382.1 2748688 D 440085 CDS YP_002421383.1 218530567 7117362 2749380..2750387 1 NC_011757.1 SMART: hypothetical protein; KEGG: mex:Mext_2336 WD-40 repeat-containing protein; hypothetical protein 2750387 7117362 Mchl_2615 Methylobacterium extorquens CM4 hypothetical protein YP_002421383.1 2749380 D 440085 CDS YP_002421384.1 218530568 7117363 2750398..2750658 1 NC_011757.1 KEGG: mex:Mext_2337 hypothetical protein; hypothetical protein 2750658 7117363 Mchl_2616 Methylobacterium extorquens CM4 hypothetical protein YP_002421384.1 2750398 D 440085 CDS YP_002421385.1 218530569 7117364 2750725..2751255 1 NC_011757.1 KEGG: mex:Mext_2338 hypothetical protein; hypothetical protein 2751255 7117364 Mchl_2617 Methylobacterium extorquens CM4 hypothetical protein YP_002421385.1 2750725 D 440085 CDS YP_002421386.1 218530570 7117365 2751385..2752617 1 NC_011757.1 KEGG: mex:Mext_2339 hypothetical protein; hypothetical protein 2752617 7117365 Mchl_2618 Methylobacterium extorquens CM4 hypothetical protein YP_002421386.1 2751385 D 440085 CDS YP_002421387.1 218530571 7117366 complement(2752622..2753062) 1 NC_011757.1 PFAM: protein of unknown function DUF1025; KEGG: mex:Mext_2340 hypothetical protein; hypothetical protein 2753062 7117366 Mchl_2619 Methylobacterium extorquens CM4 hypothetical protein YP_002421387.1 2752622 R 440085 CDS YP_002421388.1 218530572 7117367 complement(2753059..2753805) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; pyrimidine 5'-nucleotidase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_2341 pyrimidine 5'-nucleotidase; pyrimidine 5'-nucleotidase 2753805 7117367 Mchl_2620 Methylobacterium extorquens CM4 pyrimidine 5'-nucleotidase YP_002421388.1 2753059 R 440085 CDS YP_002421389.1 218530573 7117368 complement(2753893..2754789) 1 NC_011757.1 TIGRFAM: acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: mex:Mext_2342 acetylglutamate kinase; acetylglutamate kinase 2754789 7117368 Mchl_2621 Methylobacterium extorquens CM4 acetylglutamate kinase YP_002421389.1 2753893 R 440085 CDS YP_002421390.1 218530574 7117369 2755189..2755413 1 NC_011757.1 KEGG: mex:Mext_2343 hypothetical protein; hypothetical protein 2755413 7117369 Mchl_2622 Methylobacterium extorquens CM4 hypothetical protein YP_002421390.1 2755189 D 440085 CDS YP_002421391.1 218530575 7117370 complement(2755436..2756212) 1 NC_011757.1 PFAM: MOSC domain containing protein; KEGG: mex:Mext_2344 MOSC domain-containing protein; MOSC domain-containing protein 2756212 7117370 Mchl_2623 Methylobacterium extorquens CM4 MOSC domain-containing protein YP_002421391.1 2755436 R 440085 CDS YP_002421392.1 218530576 7117372 2756349..2757143 1 NC_011757.1 PFAM: MOSC domain containing protein; KEGG: mex:Mext_2345 MOSC domain-containing protein; MOSC domain-containing protein 2757143 7117372 Mchl_2624 Methylobacterium extorquens CM4 MOSC domain-containing protein YP_002421392.1 2756349 D 440085 CDS YP_002421393.1 218530577 7117374 2757372..2759996 1 NC_011757.1 KEGG: mex:Mext_2346 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; Clp domain protein; ATPase AAA; ATPase AAA; SMART: ATPase AAA; ATP-dependent chaperone ClpB 2759996 7117374 Mchl_2625 Methylobacterium extorquens CM4 ATP-dependent chaperone ClpB YP_002421393.1 2757372 D 440085 CDS YP_002421394.1 218530578 7117375 2760174..2760848 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_2347 metallophosphoesterase; metallophosphoesterase 2760848 7117375 Mchl_2626 Methylobacterium extorquens CM4 metallophosphoesterase YP_002421394.1 2760174 D 440085 CDS YP_002421395.1 218530579 7117376 2760976..2762415 1 NC_011757.1 PFAM: short chain fatty acid transporter; KEGG: mex:Mext_2348 short chain fatty acid transporter; short chain fatty acid transporter 2762415 7117376 Mchl_2627 Methylobacterium extorquens CM4 short chain fatty acid transporter YP_002421395.1 2760976 D 440085 CDS YP_002421396.1 218530580 7117377 complement(2762677..2763048) 1 NC_011757.1 PFAM: protein of unknown function DUF423; KEGG: mex:Mext_2349 hypothetical protein; hypothetical protein 2763048 7117377 Mchl_2628 Methylobacterium extorquens CM4 hypothetical protein YP_002421396.1 2762677 R 440085 CDS YP_002421397.1 218530581 7117378 complement(2763045..2763704) 1 NC_011757.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 2763704 engB 7117378 engB Methylobacterium extorquens CM4 ribosome biogenesis GTP-binding protein YsxC YP_002421397.1 2763045 R 440085 CDS YP_002421398.1 218530582 7117379 complement(2763954..2765804) 1 NC_011757.1 TIGRFAM: YidC translocase/secretase; PFAM: 60 kDa inner membrane insertion protein; KEGG: mex:Mext_2351 60 kDa inner membrane insertion protein; YidC translocase/secretase 2765804 7117379 Mchl_2630 Methylobacterium extorquens CM4 YidC translocase/secretase YP_002421398.1 2763954 R 440085 CDS YP_002421399.1 218530583 7117380 complement(2765797..2766294) 1 NC_011757.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein; KEGG: mex:Mext_2352 ribonuclease P protein component; ribonuclease P protein component 2766294 7117380 Mchl_2631 Methylobacterium extorquens CM4 ribonuclease P protein component YP_002421399.1 2765797 R 440085 CDS YP_002421400.1 218530584 7117381 complement(2766370..2766504) 1 NC_011757.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2766504 rpmH 7117381 rpmH Methylobacterium extorquens CM4 50S ribosomal protein L34 YP_002421400.1 2766370 R 440085 CDS YP_002421401.1 218530585 7117382 2767171..2767704 1 NC_011757.1 PFAM: protein of unknown function DUF1465; KEGG: mex:Mext_2354 hypothetical protein; hypothetical protein 2767704 7117382 Mchl_2633 Methylobacterium extorquens CM4 hypothetical protein YP_002421401.1 2767171 D 440085 CDS YP_002421402.1 218530586 7117383 complement(2768038..2768292) 1 NC_011757.1 TIGRFAM: ribosomal protein L31; KEGG: mex:Mext_2355 ribosomal protein L31; 50S ribosomal protein L31 2768292 7117383 Mchl_2634 Methylobacterium extorquens CM4 50S ribosomal protein L31 YP_002421402.1 2768038 R 440085 CDS YP_002421403.1 218530587 7117384 2768589..2770445 1 NC_011757.1 KEGG: mex:Mext_2356 lipid ABC transporter ATPase/inner membrane protein; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: ATPase AAA; lipid A ABC exporter family, fused ATPase and inner membrane subunits 2770445 7117384 Mchl_2635 Methylobacterium extorquens CM4 lipid A ABC exporter family, fused ATPase and inner membrane subunits YP_002421403.1 2768589 D 440085 CDS YP_002421404.1 218530588 7117385 2770598..2771605 1 NC_011757.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2771605 7117385 Mchl_2636 Methylobacterium extorquens CM4 D-cysteine desulfhydrase YP_002421404.1 2770598 D 440085 CDS YP_002421405.1 218530589 7117386 complement(2771645..2772658) 1 NC_011757.1 PFAM: OmpA/MotB domain protein; KEGG: mex:Mext_2360 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 2772658 7117386 Mchl_2637 Methylobacterium extorquens CM4 OmpA/MotB domain-containing protein YP_002421405.1 2771645 R 440085 CDS YP_002421406.1 218530590 7117387 complement(2772659..2773654) 1 NC_011757.1 KEGG: mex:Mext_2361 hypothetical protein; hypothetical protein 2773654 7117387 Mchl_2638 Methylobacterium extorquens CM4 hypothetical protein YP_002421406.1 2772659 R 440085 CDS YP_002421407.1 218530591 7117388 complement(2773816..2774637) 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_2362 metallophosphoesterase; metallophosphoesterase 2774637 7117388 Mchl_2639 Methylobacterium extorquens CM4 metallophosphoesterase YP_002421407.1 2773816 R 440085 CDS YP_002421408.1 218530592 7117389 complement(2774703..2775293) 1 NC_011757.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: mex:Mext_2363 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 2775293 7117389 Mchl_2640 Methylobacterium extorquens CM4 5-formyltetrahydrofolate cyclo-ligase YP_002421408.1 2774703 R 440085 CDS YP_002421409.1 218530593 7117391 complement(2775541..2775912) 1 NC_011757.1 PFAM: protein of unknown function DUF710; KEGG: mex:Mext_2364 hypothetical protein; hypothetical protein 2775912 7117391 Mchl_2641 Methylobacterium extorquens CM4 hypothetical protein YP_002421409.1 2775541 R 440085 CDS YP_002421410.1 218530594 7117392 complement(2775936..2776256) 1 NC_011757.1 KEGG: mex:Mext_2365 hypothetical protein; hypothetical protein 2776256 7117392 Mchl_2642 Methylobacterium extorquens CM4 hypothetical protein YP_002421410.1 2775936 R 440085 CDS YP_002421411.1 218530595 7117393 2776719..2777726 1 NC_011757.1 KEGG: mex:Mext_2366 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2777726 7117393 Mchl_2643 Methylobacterium extorquens CM4 glyceraldehyde-3-phosphate dehydrogenase YP_002421411.1 2776719 D 440085 CDS YP_002421412.1 218530596 7117394 2777921..2778427 1 NC_011757.1 KEGG: mex:Mext_2367 hypothetical protein; hypothetical protein 2778427 7117394 Mchl_2644 Methylobacterium extorquens CM4 hypothetical protein YP_002421412.1 2777921 D 440085 CDS YP_002421413.1 218530597 7117395 2778443..2779645 1 NC_011757.1 PFAM: phosphoglycerate kinase; KEGG: mex:Mext_2368 phosphoglycerate kinase; phosphoglycerate kinase 2779645 7117395 Mchl_2645 Methylobacterium extorquens CM4 phosphoglycerate kinase YP_002421413.1 2778443 D 440085 CDS YP_002421414.1 218530598 7117396 2779798..2780865 1 NC_011757.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 2780865 7117396 Mchl_2646 Methylobacterium extorquens CM4 fructose-1,6-bisphosphate aldolase YP_002421414.1 2779798 D 440085 CDS YP_002421415.1 218530599 7117397 2780872..2781540 1 NC_011757.1 PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase; thiamine monophosphate synthase 2781540 7117397 Mchl_2647 Methylobacterium extorquens CM4 thiamine monophosphate synthase YP_002421415.1 2780872 D 440085 CDS YP_002421416.1 218530600 7117398 2781642..2782685 1 NC_011757.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mex:Mext_2371 Sel1 domain-containing protein; Sel1 domain-containing protein repeat-containing protein 2782685 7117398 Mchl_2648 Methylobacterium extorquens CM4 Sel1 domain-containing protein repeat-containing protein YP_002421416.1 2781642 D 440085 CDS YP_002421417.1 218530601 7117399 2782915..2784318 1 NC_011757.1 PFAM: amino acid permease-associated region; KEGG: mex:Mext_2372 amino acid permease-associated region; amino acid permease-associated protein 2784318 7117399 Mchl_2649 Methylobacterium extorquens CM4 amino acid permease-associated protein YP_002421417.1 2782915 D 440085 CDS YP_002421418.1 218530602 7117400 complement(2784329..2785852) 1 NC_011757.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: mex:Mext_2373 carbohydrate kinase, YjeF related protein; carbohydrate kinase 2785852 7117400 Mchl_2650 Methylobacterium extorquens CM4 carbohydrate kinase YP_002421418.1 2784329 R 440085 CDS YP_002421419.1 218530603 7117401 2786037..2786375 1 NC_011757.1 PFAM: nitrogen regulatory protein P-II; KEGG: mrd:Mrad2831_5130 nitrogen regulatory protein P-II; nitrogen regulatory protein P-II 2786375 7117401 Mchl_2651 Methylobacterium extorquens CM4 nitrogen regulatory protein P-II YP_002421419.1 2786037 D 440085 CDS YP_002421420.1 218530604 7117402 2786462..2787391 1 NC_011757.1 catalyzes the formation of glutamate from glutamine; glutaminase 2787391 7117402 Mchl_2652 Methylobacterium extorquens CM4 glutaminase YP_002421420.1 2786462 D 440085 CDS YP_002421421.1 218530605 7117403 complement(2787566..2788612) 1 NC_011757.1 PFAM: glutamine synthetase; glutamine synthetase beta-Grasp; KEGG: mex:Mext_2376 glutamate--ammonia ligase; glutamate--ammonia ligase 2788612 7117403 Mchl_2653 Methylobacterium extorquens CM4 glutamate--ammonia ligase YP_002421421.1 2787566 R 440085 CDS YP_002421422.1 218530606 7117404 2789188..2790597 1 NC_011757.1 TIGRFAM: glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: mex:Mext_2377 glutamine synthetase; glutamine synthetase 2790597 7117404 Mchl_2654 Methylobacterium extorquens CM4 glutamine synthetase YP_002421422.1 2789188 D 440085 CDS YP_002421423.1 218530607 7117405 2790730..2791308 1 NC_011757.1 PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_2378 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 2791308 7117405 Mchl_2655 Methylobacterium extorquens CM4 NADPH-dependent FMN reductase YP_002421423.1 2790730 D 440085 CDS YP_002421424.1 218530608 7117406 2791453..2791791 1 NC_011757.1 KEGG: mex:Mext_2379 hypothetical protein; hypothetical protein 2791791 7117406 Mchl_2656 Methylobacterium extorquens CM4 hypothetical protein YP_002421424.1 2791453 D 440085 CDS YP_002421425.1 218530609 7117407 2791950..2794316 1 NC_011757.1 KEGG: mex:Mext_2380 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; ribonuclease R 2794316 7117407 Mchl_2657 Methylobacterium extorquens CM4 ribonuclease R YP_002421425.1 2791950 D 440085 CDS YP_002421426.1 218530610 7117408 2794340..2794837 1 NC_011757.1 PFAM: protein of unknown function DUF983; KEGG: mex:Mext_2381 hypothetical protein; hypothetical protein 2794837 7117408 Mchl_2658 Methylobacterium extorquens CM4 hypothetical protein YP_002421426.1 2794340 D 440085 CDS YP_002421427.1 218530611 7117409 2794788..2795561 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_2382 NUDIX hydrolase; NUDIX hydrolase 2795561 7117409 Mchl_2659 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002421427.1 2794788 D 440085 CDS YP_002421428.1 218530612 7117410 2795683..2797647 1 NC_011757.1 KEGG: mex:Mext_2383 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; type IV pilus assembly PilZ; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 2797647 7117410 Mchl_2660 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor YP_002421428.1 2795683 D 440085 CDS YP_002421429.1 218530613 7117411 complement(2797709..2798578) 1 NC_011757.1 KEGG: mex:Mext_2384 hypothetical protein; hypothetical protein 2798578 7117411 Mchl_2661 Methylobacterium extorquens CM4 hypothetical protein YP_002421429.1 2797709 R 440085 CDS YP_002421430.1 218530614 7117412 complement(2798585..2799763) 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; hypothetical protein; KEGG: mex:Mext_2385 hypothetical protein; hypothetical protein 2799763 7117412 Mchl_2662 Methylobacterium extorquens CM4 hypothetical protein YP_002421430.1 2798585 R 440085 CDS YP_002421431.1 218530615 7117413 complement(2799760..2800452) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_2386 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 2800452 7117413 Mchl_2663 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002421431.1 2799760 R 440085 CDS YP_002421432.1 218530616 7117414 2800680..2801531 1 NC_011757.1 KEGG: mex:Mext_2387 undecaprenol kinase; TIGRFAM: undecaprenol kinase; PFAM: bacitracin resistance protein BacA; undecaprenol kinase 2801531 7117414 Mchl_2664 Methylobacterium extorquens CM4 undecaprenol kinase YP_002421432.1 2800680 D 440085 CDS YP_002421433.1 218530617 7117415 2801680..2803497 1 NC_011757.1 PFAM: methylmalonyl-CoA mutase; KEGG: mex:Mext_2388 methylmalonyl-CoA mutase; methylmalonyl-CoA mutase 2803497 7117415 Mchl_2665 Methylobacterium extorquens CM4 methylmalonyl-CoA mutase YP_002421433.1 2801680 D 440085 CDS YP_002421434.1 218530618 7117416 2803605..2803997 1 NC_011757.1 KEGG: mex:Mext_2389 hypothetical protein; hypothetical protein 2803997 7117416 Mchl_2666 Methylobacterium extorquens CM4 hypothetical protein YP_002421434.1 2803605 D 440085 CDS YP_002421435.1 218530619 7117417 2804172..2804639 1 NC_011757.1 KEGG: mex:Mext_2390 hypothetical protein; hypothetical protein 2804639 7117417 Mchl_2667 Methylobacterium extorquens CM4 hypothetical protein YP_002421435.1 2804172 D 440085 CDS YP_002421436.1 218530620 7117418 complement(2804662..2805105) 1 NC_011757.1 KEGG: mex:Mext_2391 hypothetical protein; hypothetical protein 2805105 7117418 Mchl_2668 Methylobacterium extorquens CM4 hypothetical protein YP_002421436.1 2804662 R 440085 CDS YP_002421437.1 218530621 7117419 2805280..2805831 1 NC_011757.1 KEGG: mex:Mext_2392 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 2805831 7117419 Mchl_2669 Methylobacterium extorquens CM4 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002421437.1 2805280 D 440085 CDS YP_002421438.1 218530622 7117420 2805965..2807023 1 NC_011757.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3691 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 2807023 7117420 Mchl_2670 Methylobacterium extorquens CM4 dTDP-glucose 4,6-dehydratase YP_002421438.1 2805965 D 440085 CDS YP_002421439.1 218530623 7117421 2807026..2807916 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3692 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 2807916 7117421 Mchl_2671 Methylobacterium extorquens CM4 dTDP-4-dehydrorhamnose reductase YP_002421439.1 2807026 D 440085 CDS YP_002421440.1 218530624 7117422 2807933..2808823 1 NC_011757.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; KEGG: mex:Mext_2395 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 2808823 7117422 Mchl_2672 Methylobacterium extorquens CM4 glucose-1-phosphate thymidylyltransferase YP_002421440.1 2807933 D 440085 CDS YP_002421441.1 218530625 7117423 complement(2808955..2809593) 1 NC_011757.1 KEGG: mex:Mext_2396 hypothetical protein; hypothetical protein 2809593 7117423 Mchl_2673 Methylobacterium extorquens CM4 hypothetical protein YP_002421441.1 2808955 R 440085 CDS YP_002421442.1 218530626 7117424 complement(2809684..2810553) 1 NC_011757.1 PFAM: secretion protein HlyD; KEGG: mex:Mext_2397 secretion protein HlyD; secretion protein HlyD 2810553 7117424 Mchl_2674 Methylobacterium extorquens CM4 secretion protein HlyD YP_002421442.1 2809684 R 440085 CDS YP_002421443.1 218530627 7117425 2810576..2811028 1 NC_011757.1 KEGG: mex:Mext_2412 radical SAM domain-containing protein; hypothetical protein 2811028 7117425 Mchl_2675 Methylobacterium extorquens CM4 hypothetical protein YP_002421443.1 2810576 D 440085 CDS YP_002421444.1 218530628 7117426 2811033..2811269 1 NC_011757.1 KEGG: mex:Mext_2413 radical SAM domain-containing protein; radical SAM domain-containing protein 2811269 7117426 Mchl_2676 Methylobacterium extorquens CM4 radical SAM domain-containing protein YP_002421444.1 2811033 D 440085 CDS YP_002421445.1 218530629 7117427 complement(2811338..2812777) 1 NC_011757.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: mex:Mext_2414 multicopper oxidase type 3; multicopper oxidase type 3 2812777 7117427 Mchl_2677 Methylobacterium extorquens CM4 multicopper oxidase type 3 YP_002421445.1 2811338 R 440085 CDS YP_002421446.1 218530630 7117429 2813159..2814595 1 NC_011757.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2814595 tig 7117429 tig Methylobacterium extorquens CM4 trigger factor YP_002421446.1 2813159 D 440085 CDS YP_002421447.1 218530631 7117430 2814727..2815353 1 NC_011757.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2815353 clpP 7117430 clpP Methylobacterium extorquens CM4 ATP-dependent Clp protease proteolytic subunit YP_002421447.1 2814727 D 440085 CDS YP_002421448.1 218530632 7117431 2815605..2816876 1 NC_011757.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2816876 clpX 7117431 clpX Methylobacterium extorquens CM4 ATP-dependent protease ATP-binding subunit ClpX YP_002421448.1 2815605 D 440085 CDS YP_002421449.1 218530633 7117432 2817144..2819564 1 NC_011757.1 KEGG: mex:Mext_2418 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent protease La 2819564 7117432 Mchl_2681 Methylobacterium extorquens CM4 ATP-dependent protease La YP_002421449.1 2817144 D 440085 CDS YP_002421450.1 218530634 7117434 2820001..2820108 1 NC_011757.1 KEGG: mpo:Mpop_2374 hypothetical protein; hypothetical protein 2820108 7117434 Mchl_2682 Methylobacterium extorquens CM4 hypothetical protein YP_002421450.1 2820001 D 440085 CDS YP_002421451.1 218530635 7117435 2820719..2821957 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_2461 glycosyl transferase group 1; group 1 glycosyl transferase 2821957 7117435 Mchl_2683 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002421451.1 2820719 D 440085 CDS YP_002421452.1 218530636 7117436 complement(2821969..2822916) 1 NC_011757.1 TIGRFAM: methyltransferase; KEGG: mex:Mext_2462 hypothetical protein; methyltransferase 2822916 7117436 Mchl_2684 Methylobacterium extorquens CM4 methyltransferase YP_002421452.1 2821969 R 440085 CDS YP_002421453.1 218530637 7117437 complement(2822913..2823938) 1 NC_011757.1 PFAM: methyltransferase small; methyltransferase type 12; KEGG: mex:Mext_2463 methyltransferase small; methyltransferase small 2823938 7117437 Mchl_2685 Methylobacterium extorquens CM4 methyltransferase small YP_002421453.1 2822913 R 440085 CDS YP_002421454.1 218530638 7117438 complement(2823941..2824696) 1 NC_011757.1 PFAM: protein of unknown function YqcI/YcgG; KEGG: mex:Mext_2464 hypothetical protein; hypothetical protein 2824696 7117438 Mchl_2686 Methylobacterium extorquens CM4 hypothetical protein YP_002421454.1 2823941 R 440085 CDS YP_002421455.1 218530639 7117439 complement(2824973..2825569) 1 NC_011757.1 KEGG: mex:Mext_2465 hypothetical protein; hypothetical protein 2825569 7117439 Mchl_2687 Methylobacterium extorquens CM4 hypothetical protein YP_002421455.1 2824973 R 440085 CDS YP_002421456.1 218530640 7117440 2825742..2827763 1 NC_011757.1 TIGRFAM: oligopeptide transporters, OPT superfamily; oligopeptide transporter OPT family; PFAM: oligopeptide transporter OPT superfamily protein; KEGG: mex:Mext_2466 OPT family oligopeptide transporter; oligopeptide transporter OPT family 2827763 7117440 Mchl_2688 Methylobacterium extorquens CM4 oligopeptide transporter OPT family YP_002421456.1 2825742 D 440085 CDS YP_002421457.1 218530641 7117441 2827832..2828626 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_2467 ABC-2 type transporter; ABC transporter 2828626 7117441 Mchl_2689 Methylobacterium extorquens CM4 ABC transporter YP_002421457.1 2827832 D 440085 CDS YP_002421458.1 218530642 7117443 complement(2829215..2829916) 1 NC_011757.1 KEGG: mex:Mext_2468 hypothetical protein; hypothetical protein 2829916 7117443 Mchl_2690 Methylobacterium extorquens CM4 hypothetical protein YP_002421458.1 2829215 R 440085 CDS YP_002421459.1 218530643 7117444 2830152..2831345 1 NC_011757.1 PFAM: ribonuclease BN; KEGG: mex:Mext_2469 ribonuclease BN; ribonuclease BN 2831345 7117444 Mchl_2691 Methylobacterium extorquens CM4 ribonuclease BN YP_002421459.1 2830152 D 440085 CDS YP_002421460.1 218530644 7117446 complement(2831693..2832085) 1 NC_011757.1 KEGG: mex:Mext_2470 hypothetical protein; hypothetical protein 2832085 7117446 Mchl_2693 Methylobacterium extorquens CM4 hypothetical protein YP_002421460.1 2831693 R 440085 CDS YP_002421461.1 218530645 7117447 2832590..2835733 1 NC_011757.1 KEGG: mex:Mext_2471 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; DNA polymerase I 2835733 7117447 Mchl_2694 Methylobacterium extorquens CM4 DNA polymerase I YP_002421461.1 2832590 D 440085 CDS YP_002421462.1 218530646 7117448 complement(2835917..2836579) 1 NC_011757.1 PFAM: endonuclease V; KEGG: mex:Mext_2472 deoxyribonuclease V; deoxyribonuclease V 2836579 7117448 Mchl_2695 Methylobacterium extorquens CM4 deoxyribonuclease V YP_002421462.1 2835917 R 440085 CDS YP_002421463.1 218530647 7117449 complement(2836593..2837690) 1 NC_011757.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2837690 7117449 Mchl_2696 Methylobacterium extorquens CM4 GTP-dependent nucleic acid-binding protein EngD YP_002421463.1 2836593 R 440085 CDS YP_002421464.1 218530648 7117450 complement(2837770..2838402) 1 NC_011757.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2838402 7117450 Mchl_2697 Methylobacterium extorquens CM4 peptidyl-tRNA hydrolase YP_002421464.1 2837770 R 440085 CDS YP_002421465.1 218530649 7117451 complement(2838504..2839190) 1 NC_011757.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 2839190 7117451 Mchl_2698 Methylobacterium extorquens CM4 50S ribosomal protein L25/general stress protein Ctc YP_002421465.1 2838504 R 440085 CDS YP_002421466.1 218530650 7117452 complement(2839471..2839950) 1 NC_011757.1 KEGG: mex:Mext_2476 hypothetical protein; hypothetical protein 2839950 7117452 Mchl_2699 Methylobacterium extorquens CM4 hypothetical protein YP_002421466.1 2839471 R 440085 CDS YP_002421467.1 218530651 7117453 2840302..2840487 1 NC_011757.1 PFAM: Flp/Fap pilin component; KEGG: mpo:Mpop_2405 Flp/Fap pilin component; Flp/Fap pilin component 2840487 7117453 Mchl_2700 Methylobacterium extorquens CM4 Flp/Fap pilin component YP_002421467.1 2840302 D 440085 CDS YP_002421468.1 218530652 7117454 2840756..2841253 1 NC_011757.1 PFAM: peptidase A24A prepilin type IV; KEGG: mpo:Mpop_2406 peptidase A24A prepilin type IV; peptidase A24A prepilin type IV 2841253 7117454 Mchl_2701 Methylobacterium extorquens CM4 peptidase A24A prepilin type IV YP_002421468.1 2840756 D 440085 CDS YP_002421469.1 218530653 7114609 2841495..2842280 1 NC_011757.1 TIGRFAM: Flp pilus assembly protein CpaB; PFAM: SAF domain protein; KEGG: mex:Mext_2479 Flp pilus assembly protein CpaB; Flp pilus assembly protein CpaB 2842280 7114609 Mchl_2702 Methylobacterium extorquens CM4 Flp pilus assembly protein CpaB YP_002421469.1 2841495 D 440085 CDS YP_002421470.1 218530654 7114610 2842292..2843791 1 NC_011757.1 PFAM: type II and III secretion system protein; transport-associated; KEGG: mex:Mext_2480 type II and III secretion system protein; type II and III secretion system protein 2843791 7114610 Mchl_2703 Methylobacterium extorquens CM4 type II and III secretion system protein YP_002421470.1 2842292 D 440085 CDS YP_002421471.1 218530655 7114611 2843817..2844563 1 NC_011757.1 pilus (Caulobacter type) biogenesis lipoprotein CpaD; TIGRFAM: pilus (Caulobacter type) biogenesis lipoprotein CpaD; PFAM: pilus biogenesis CpaD family protein; KEGG: mex:Mext_2481 pilus biogenesis lipoprotein CpaD; pilus biogenesis lipoprotein CpaD 2844563 7114611 Mchl_2704 Methylobacterium extorquens CM4 pilus biogenesis lipoprotein CpaD YP_002421471.1 2843817 D 440085 CDS YP_002421472.1 218530656 7114612 2844647..2845891 1 NC_011757.1 KEGG: mex:Mext_2482 pilus assembly protein CpaE; pilus assembly protein CpaE 2845891 7114612 Mchl_2705 Methylobacterium extorquens CM4 pilus assembly protein CpaE YP_002421472.1 2844647 D 440085 CDS YP_002421473.1 218530657 7114613 2845939..2847387 1 NC_011757.1 PFAM: type II secretion system protein E; KEGG: mex:Mext_2483 type II secretion system protein E; type II secretion system protein E 2847387 7114613 Mchl_2706 Methylobacterium extorquens CM4 type II secretion system protein E YP_002421473.1 2845939 D 440085 CDS YP_002421474.1 218530658 7114197 2847384..2848355 1 NC_011757.1 PFAM: type II secretion system protein; KEGG: mex:Mext_2484 type II secretion system protein; type II secretion system protein 2848355 7114197 Mchl_2707 Methylobacterium extorquens CM4 type II secretion system protein YP_002421474.1 2847384 D 440085 CDS YP_002421475.1 218530659 7113898 2848428..2849399 1 NC_011757.1 PFAM: type II secretion system protein; KEGG: mex:Mext_2485 type II secretion system protein; type II secretion system protein 2849399 7113898 Mchl_2708 Methylobacterium extorquens CM4 type II secretion system protein YP_002421475.1 2848428 D 440085 CDS YP_002421476.1 218530660 7113899 2849500..2850498 1 NC_011757.1 PFAM: MaoC domain protein dehydratase; KEGG: mex:Mext_2486 dehydratase; MaoC domain-containing protein dehydratase 2850498 7113899 Mchl_2709 Methylobacterium extorquens CM4 MaoC domain-containing protein dehydratase YP_002421476.1 2849500 D 440085 CDS YP_002421477.1 218530661 7113900 2850495..2851757 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: mex:Mext_2487 major facilitator transporter; major facilitator superfamily protein 2851757 7113900 Mchl_2710 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421477.1 2850495 D 440085 CDS YP_002421478.1 218530662 7113901 2851899..2852324 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_2488 OsmC family protein; OsmC family protein 2852324 7113901 Mchl_2711 Methylobacterium extorquens CM4 OsmC family protein YP_002421478.1 2851899 D 440085 CDS YP_002421479.1 218530663 7113902 complement(2852475..2853056) 1 NC_011757.1 PFAM: CoA-binding protein; KEGG: mex:Mext_2489 CoA-binding domain-containing protein; CoA-binding protein 2853056 7113902 Mchl_2712 Methylobacterium extorquens CM4 CoA-binding protein YP_002421479.1 2852475 R 440085 CDS YP_002421480.1 218530664 7113903 2853083..2853514 1 NC_011757.1 PFAM: thioesterase superfamily protein; KEGG: mex:Mext_2490 thioesterase superfamily protein; thioesterase superfamily protein 2853514 7113903 Mchl_2713 Methylobacterium extorquens CM4 thioesterase superfamily protein YP_002421480.1 2853083 D 440085 CDS YP_002421481.1 218530665 7113904 complement(2853570..2854889) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_2491 major facilitator transporter; major facilitator superfamily protein 2854889 7113904 Mchl_2714 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421481.1 2853570 R 440085 CDS YP_002421482.1 218530666 7113905 2855259..2856785 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_2492 diguanylate cyclase; diguanylate cyclase 2856785 7113905 Mchl_2715 Methylobacterium extorquens CM4 diguanylate cyclase YP_002421482.1 2855259 D 440085 CDS YP_002421483.1 218530667 7113906 complement(2856858..2857277) 1 NC_011757.1 PFAM: BA14K family protein; KEGG: mex:Mext_2493 BA14K family protein; BA14K family protein 2857277 7113906 Mchl_2716 Methylobacterium extorquens CM4 BA14K family protein YP_002421483.1 2856858 R 440085 CDS YP_002421484.1 218530668 7113907 complement(2857428..2858339) 1 NC_011757.1 KEGG: mex:Mext_2494 hypothetical protein; hypothetical protein 2858339 7113907 Mchl_2717 Methylobacterium extorquens CM4 hypothetical protein YP_002421484.1 2857428 R 440085 CDS YP_002421485.1 218530669 7113908 complement(2858387..2858719) 1 NC_011757.1 PFAM: CsbD family protein; KEGG: mex:Mext_2495 CsbD family protein; CsbD family protein 2858719 7113908 Mchl_2718 Methylobacterium extorquens CM4 CsbD family protein YP_002421485.1 2858387 R 440085 CDS YP_002421486.1 218530670 7113909 2859037..2859402 1 NC_011757.1 KEGG: mex:Mext_2496 hypothetical protein; hypothetical protein 2859402 7113909 Mchl_2719 Methylobacterium extorquens CM4 hypothetical protein YP_002421486.1 2859037 D 440085 CDS YP_002421487.1 218530671 7113910 2859512..2860141 1 NC_011757.1 PFAM: 3'-5' exonuclease; KEGG: mex:Mext_2497 3'-5' exonuclease; 3'-5' exonuclease 2860141 7113910 Mchl_2720 Methylobacterium extorquens CM4 3'-5' exonuclease YP_002421487.1 2859512 D 440085 CDS YP_002421488.1 218530672 7113911 2860412..2861170 1 NC_011757.1 PFAM: protein of unknown function DUF1239; KEGG: mex:Mext_2498 hypothetical protein; hypothetical protein 2861170 7113911 Mchl_2721 Methylobacterium extorquens CM4 hypothetical protein YP_002421488.1 2860412 D 440085 CDS YP_002421489.1 218530673 7113912 2861167..2861907 1 NC_011757.1 PFAM: OstA family protein; KEGG: mex:Mext_2499 OstA family protein; OstA family protein 2861907 7113912 Mchl_2722 Methylobacterium extorquens CM4 OstA family protein YP_002421489.1 2861167 D 440085 CDS YP_002421490.1 218530674 7113913 2861925..2862797 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_2500 ABC transporter; ABC transporter 2862797 7113913 Mchl_2723 Methylobacterium extorquens CM4 ABC transporter YP_002421490.1 2861925 D 440085 CDS YP_002421491.1 218530675 7113914 2863372..2864907 1 NC_011757.1 TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: mex:Mext_2501 RNA polymerase sigma-54 factor, RpoN; RNA polymerase sigma-54 subunit RpoN 2864907 7113914 Mchl_2724 Methylobacterium extorquens CM4 RNA polymerase sigma-54 subunit RpoN YP_002421491.1 2863372 D 440085 CDS YP_002421492.1 218530676 7113915 2865021..2865629 1 NC_011757.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: mex:Mext_2502 ribosomal subunit interface protein; sigma 54 modulation protein/ribosomal protein S30EA 2865629 7113915 Mchl_2725 Methylobacterium extorquens CM4 sigma 54 modulation protein/ribosomal protein S30EA YP_002421492.1 2865021 D 440085 CDS YP_002421493.1 218530677 7113916 2865828..2866295 1 NC_011757.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: mex:Mext_2503 PTS IIA-like nitrogen-regulatory protein PtsN; PTS IIA-like nitrogen-regulatory protein PtsN 2866295 7113916 Mchl_2726 Methylobacterium extorquens CM4 PTS IIA-like nitrogen-regulatory protein PtsN YP_002421493.1 2865828 D 440085 CDS YP_002421494.1 218530678 7113917 2866297..2866626 1 NC_011757.1 KEGG: mex:Mext_2504 hypothetical protein; hypothetical protein 2866626 7113917 Mchl_2727 Methylobacterium extorquens CM4 hypothetical protein YP_002421494.1 2866297 D 440085 CDS YP_002421495.1 218530679 7113918 2866762..2867775 1 NC_011757.1 KEGG: mex:Mext_2505 magnesium chelatase ATPase I; TIGRFAM: magnesium chelatase ATPase I; PFAM: magnesium chelatase ChlI subunit; SMART: ATPase AAA; magnesium chelatase ATPase I 2867775 7113918 Mchl_2728 Methylobacterium extorquens CM4 magnesium chelatase ATPase I YP_002421495.1 2866762 D 440085 CDS YP_002421496.1 218530680 7113919 complement(2867798..2868436) 1 NC_011757.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2868436 7113919 Mchl_2729 Methylobacterium extorquens CM4 phosphoglyceromutase YP_002421496.1 2867798 R 440085 CDS YP_002421497.1 218530681 7113920 complement(2868573..2869376) 1 NC_011757.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 2869376 7113920 Mchl_2730 Methylobacterium extorquens CM4 dihydrodipicolinate reductase YP_002421497.1 2868573 R 440085 CDS YP_002421498.1 218530682 7113921 complement(2869451..2870146) 1 NC_011757.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: mex:Mext_2508 multiple antibiotic resistance (MarC)-related protein; multiple antibiotic resistance (MarC)-like protein 2870146 7113921 Mchl_2731 Methylobacterium extorquens CM4 multiple antibiotic resistance (MarC)-like protein YP_002421498.1 2869451 R 440085 CDS YP_002421499.1 218530683 7113922 complement(2870184..2870936) 1 NC_011757.1 PFAM: methyltransferase type 11; KEGG: mpo:Mpop_2437 methyltransferase type 11; type 11 methyltransferase 2870936 7113922 Mchl_2732 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002421499.1 2870184 R 440085 CDS YP_002421500.1 218530684 7113923 2871150..2871929 1 NC_011757.1 KEGG: mex:Mext_2510 hydroxyacylglutathione hydrolase; TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein; hydroxyacylglutathione hydrolase 2871929 7113923 Mchl_2733 Methylobacterium extorquens CM4 hydroxyacylglutathione hydrolase YP_002421500.1 2871150 D 440085 CDS YP_002421501.1 218530685 7113924 2872115..2872342 1 NC_011757.1 KEGG: mex:Mext_2511 hypothetical protein; hypothetical protein 2872342 7113924 Mchl_2734 Methylobacterium extorquens CM4 hypothetical protein YP_002421501.1 2872115 D 440085 CDS YP_002421502.1 218530686 7113925 2872339..2873325 1 NC_011757.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase; KEGG: mex:Mext_2512 tyrosine recombinase XerD; tyrosine recombinase XerD 2873325 7113925 Mchl_2735 Methylobacterium extorquens CM4 tyrosine recombinase XerD YP_002421502.1 2872339 D 440085 CDS YP_002421503.1 218530687 7113926 2873496..2874713 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_2513 diguanylate cyclase; diguanylate cyclase 2874713 7113926 Mchl_2736 Methylobacterium extorquens CM4 diguanylate cyclase YP_002421503.1 2873496 D 440085 CDS YP_002421504.1 218530688 7113927 2874847..2877078 1 NC_011757.1 PFAM: glycoside hydrolase; KEGG: mex:Mext_2514 glycoside hydrolase family 3 protein; glycoside hydrolase 2877078 7113927 Mchl_2737 Methylobacterium extorquens CM4 glycoside hydrolase YP_002421504.1 2874847 D 440085 CDS YP_002421505.1 218530689 7113928 complement(2877085..2878287) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_2515 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 2878287 7113928 Mchl_2738 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002421505.1 2877085 R 440085 CDS YP_002421506.1 218530690 7113929 complement(2878325..2878849) 1 NC_011757.1 KEGG: mex:Mext_2516 hypothetical protein; hypothetical protein 2878849 7113929 Mchl_2739 Methylobacterium extorquens CM4 hypothetical protein YP_002421506.1 2878325 R 440085 CDS YP_002421507.1 218530691 7113930 complement(2878846..2880030) 1 NC_011757.1 PFAM: aminotransferase class V; aminotransferase class I and II; KEGG: mex:Mext_2517 hypothetical protein; hypothetical protein 2880030 7113930 Mchl_2740 Methylobacterium extorquens CM4 hypothetical protein YP_002421507.1 2878846 R 440085 CDS YP_002421508.1 218530692 7113931 2880468..2880641 1 NC_011757.1 KEGG: mpo:Mpop_2446 hypothetical protein; hypothetical protein 2880641 7113931 Mchl_2741 Methylobacterium extorquens CM4 hypothetical protein YP_002421508.1 2880468 D 440085 CDS YP_002421509.1 218530693 7113932 2880799..2882187 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_2519 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 2882187 7113932 Mchl_2742 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002421509.1 2880799 D 440085 CDS YP_002421510.1 218530694 7113933 2882200..2885337 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_2520 acriflavin resistance protein; acriflavin resistance protein 2885337 7113933 Mchl_2743 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002421510.1 2882200 D 440085 CDS YP_002421511.1 218530695 7113934 2885334..2888648 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_2521 acriflavin resistance protein; acriflavin resistance protein 2888648 7113934 Mchl_2744 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002421511.1 2885334 D 440085 CDS YP_002421512.1 218530696 7113935 2888815..2890317 1 NC_011757.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: mex:Mext_2522 RND efflux system outer membrane lipoprotein; NodT family RND efflux system outer membrane lipoprotein 2890317 7113935 Mchl_2745 Methylobacterium extorquens CM4 NodT family RND efflux system outer membrane lipoprotein YP_002421512.1 2888815 D 440085 CDS YP_002421513.1 218530697 7113936 2890432..2891940 1 NC_011757.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2891940 7113936 Mchl_2746 Methylobacterium extorquens CM4 glucose-6-phosphate 1-dehydrogenase YP_002421513.1 2890432 D 440085 CDS YP_002421514.1 218530698 7113937 complement(2892050..2893159) 1 NC_011757.1 KEGG: mpo:Mpop_2452 3-isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 2893159 7113937 Mchl_2747 Methylobacterium extorquens CM4 3-isopropylmalate dehydrogenase YP_002421514.1 2892050 R 440085 CDS YP_002421515.1 218530699 7113938 complement(2893268..2893585) 1 NC_011757.1 KEGG: mex:Mext_2525 hypothetical protein; hypothetical protein 2893585 7113938 Mchl_2748 Methylobacterium extorquens CM4 hypothetical protein YP_002421515.1 2893268 R 440085 CDS YP_002421516.1 218530700 7113939 2893832..2895367 1 NC_011757.1 KEGG: mex:Mext_2526 hypothetical protein; hypothetical protein 2895367 7113939 Mchl_2749 Methylobacterium extorquens CM4 hypothetical protein YP_002421516.1 2893832 D 440085 CDS YP_002421517.1 218530701 7113940 2895527..2897215 1 NC_011757.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mex:Mext_2527 thiamine pyrophosphate binding domain-containing protein; thiamine pyrophosphate TPP binding domain-containing protein 2897215 7113940 Mchl_2750 Methylobacterium extorquens CM4 thiamine pyrophosphate TPP binding domain-containing protein YP_002421517.1 2895527 D 440085 CDS YP_002421518.1 218530702 7113941 2897236..2897667 1 NC_011757.1 PFAM: thiol-disulphide oxidoreductase DCC; KEGG: mex:Mext_2528 thiol-disulphide oxidoreductase DCC; thiol-disulfide oxidoreductase DCC 2897667 7113941 Mchl_2751 Methylobacterium extorquens CM4 thiol-disulfide oxidoreductase DCC YP_002421518.1 2897236 D 440085 CDS YP_002421519.1 218530703 7113942 complement(2897835..2898797) 1 NC_011757.1 PFAM: polyprenyl synthetase; KEGG: mex:Mext_2529 polyprenyl synthetase; polyprenyl synthetase 2898797 7113942 Mchl_2752 Methylobacterium extorquens CM4 polyprenyl synthetase YP_002421519.1 2897835 R 440085 CDS YP_002421520.1 218530704 7113943 2898834..2899619 1 NC_011757.1 TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: glycosyl transferase family 51; KEGG: mex:Mext_2530 monofunctional biosynthetic peptidoglycan transglycosylase; monofunctional biosynthetic peptidoglycan transglycosylase 2899619 7113943 Mchl_2753 Methylobacterium extorquens CM4 monofunctional biosynthetic peptidoglycan transglycosylase YP_002421520.1 2898834 D 440085 CDS YP_002421521.1 218530705 7113944 complement(2899624..2901027) 1 NC_011757.1 PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: mex:Mext_2531 deoxyribodipyrimidine photo-lyase; deoxyribodipyrimidine photo-lyase 2901027 7113944 Mchl_2754 Methylobacterium extorquens CM4 deoxyribodipyrimidine photo-lyase YP_002421521.1 2899624 R 440085 CDS YP_002421522.1 218530706 7113945 complement(2901645..2902766) 1 NC_011757.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: mex:Mext_2532 TRAP dicarboxylate transporter-DctP subunit; TRAP dicarboxylate transporter subunit DctP 2902766 7113945 Mchl_2755 Methylobacterium extorquens CM4 TRAP dicarboxylate transporter subunit DctP YP_002421522.1 2901645 R 440085 CDS YP_002421523.1 218530707 7113946 2902901..2903476 1 NC_011757.1 KEGG: mex:Mext_2533 protein tyrosine phosphatase; protein tyrosine phosphatase 2903476 7113946 Mchl_2756 Methylobacterium extorquens CM4 protein tyrosine phosphatase YP_002421523.1 2902901 D 440085 CDS YP_002421524.1 218530708 7113947 complement(2903486..2904610) 1 NC_011757.1 PFAM: extracellular ligand-binding receptor; KEGG: mex:Mext_2534 extracellular ligand-binding receptor; extracellular ligand-binding receptor 2904610 7113947 Mchl_2757 Methylobacterium extorquens CM4 extracellular ligand-binding receptor YP_002421524.1 2903486 R 440085 CDS YP_002421525.1 218530709 7113948 complement(2904929..2906101) 1 NC_011757.1 PFAM: polysaccharide export protein; KEGG: mex:Mext_2535 polysaccharide export protein; polysaccharide export protein 2906101 7113948 Mchl_2758 Methylobacterium extorquens CM4 polysaccharide export protein YP_002421525.1 2904929 R 440085 CDS YP_002421526.1 218530710 7113949 complement(2906299..2907768) 1 NC_011757.1 PFAM: sulfatase; KEGG: mex:Mext_2536 sulfatase; sulfatase 2907768 7113949 Mchl_2759 Methylobacterium extorquens CM4 sulfatase YP_002421526.1 2906299 R 440085 CDS YP_002421527.1 218530711 7113950 complement(2907775..2909724) 1 NC_011757.1 PFAM: capsule polysaccharide biosynthesis protein; KEGG: mex:Mext_2537 capsule polysaccharide biosynthesis protein; capsule polysaccharide biosynthesis protein 2909724 7113950 Mchl_2760 Methylobacterium extorquens CM4 capsule polysaccharide biosynthesis protein YP_002421527.1 2907775 R 440085 CDS YP_002421528.1 218530712 7113951 2910087..2911394 1 NC_011757.1 PFAM: capsule polysaccharide biosynthesis protein; KEGG: mex:Mext_2538 capsule polysaccharide biosynthesis protein; capsule polysaccharide biosynthesis protein 2911394 7113951 Mchl_2761 Methylobacterium extorquens CM4 capsule polysaccharide biosynthesis protein YP_002421528.1 2910087 D 440085 CDS YP_002421529.1 218530713 7113952 2911451..2912218 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_2539 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 2912218 7113952 Mchl_2762 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002421529.1 2911451 D 440085 CDS YP_002421530.1 218530714 7113953 2912218..2913075 1 NC_011757.1 PFAM: formyl transferase; KEGG: mex:Mext_2540 formyl transferase domain-containing protein; formyl transferase 2913075 7113953 Mchl_2763 Methylobacterium extorquens CM4 formyl transferase YP_002421530.1 2912218 D 440085 CDS YP_002421531.1 218530715 7113954 complement(2913079..2914359) 1 NC_011757.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 2914359 7113954 Mchl_2764 Methylobacterium extorquens CM4 O-acetylhomoserine aminocarboxypropyltransferase YP_002421531.1 2913079 R 440085 CDS YP_002421532.1 218530716 7113955 2914764..2915312 1 NC_011757.1 TIGRFAM: ubiquinol-cytochrome C reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein; Ubiquinol-cytochrome C reductase iron-sulfur subunit; KEGG: mex:Mext_2542 ubiquinol-cytochrome C reductase, iron-sulfur subunit; ubiquinol-cytochrome C reductase, iron-sulfur subunit 2915312 7113955 Mchl_2765 Methylobacterium extorquens CM4 ubiquinol-cytochrome C reductase, iron-sulfur subunit YP_002421532.1 2914764 D 440085 CDS YP_002421533.1 218530717 7113956 2915347..2916639 1 NC_011757.1 PFAM: cytochrome b/b6 domain; KEGG: mex:Mext_2543 cytochrome b/b6 domain-containing protein; cytochrome b/b6 domain 2916639 7113956 Mchl_2766 Methylobacterium extorquens CM4 cytochrome b/b6 domain YP_002421533.1 2915347 D 440085 CDS YP_002421534.1 218530718 7113957 2916661..2917554 1 NC_011757.1 PFAM: cytochrome C1; KEGG: mex:Mext_2544 cytochrome C1; cytochrome C1 2917554 7113957 Mchl_2767 Methylobacterium extorquens CM4 cytochrome C1 YP_002421534.1 2916661 D 440085 CDS YP_002421535.1 218530719 7113958 2917766..2918641 1 NC_011757.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 2918641 7113958 Mchl_2768 Methylobacterium extorquens CM4 5'-methylthioadenosine phosphorylase YP_002421535.1 2917766 D 440085 CDS YP_002421536.1 218530720 7113959 complement(2918746..2919009) 1 NC_011757.1 KEGG: mex:Mext_2546 hypothetical protein; hypothetical protein 2919009 7113959 Mchl_2769 Methylobacterium extorquens CM4 hypothetical protein YP_002421536.1 2918746 R 440085 CDS YP_002421537.1 218530721 7113960 complement(2919044..2919949) 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_2547 metallophosphoesterase; metallophosphoesterase 2919949 7113960 Mchl_2770 Methylobacterium extorquens CM4 metallophosphoesterase YP_002421537.1 2919044 R 440085 CDS YP_002421538.1 218530722 7113961 2920160..2920747 1 NC_011757.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2920747 hisB 7113961 hisB Methylobacterium extorquens CM4 imidazoleglycerol-phosphate dehydratase YP_002421538.1 2920160 D 440085 CDS YP_002421539.1 218530723 7113962 2920770..2921273 1 NC_011757.1 KEGG: mex:Mext_2549 hypothetical protein; hypothetical protein 2921273 7113962 Mchl_2772 Methylobacterium extorquens CM4 hypothetical protein YP_002421539.1 2920770 D 440085 CDS YP_002421540.1 218530724 7113963 2921270..2921932 1 NC_011757.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2921932 hisH 7113963 hisH Methylobacterium extorquens CM4 imidazole glycerol phosphate synthase subunit HisH YP_002421540.1 2921270 D 440085 CDS YP_002421541.1 218530725 7113964 2921974..2922741 1 NC_011757.1 TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: mex:Mext_2551 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 2922741 7113964 Mchl_2774 Methylobacterium extorquens CM4 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_002421541.1 2921974 D 440085 CDS YP_002421542.1 218530726 7113965 2922789..2923565 1 NC_011757.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2923565 7113965 Mchl_2775 Methylobacterium extorquens CM4 imidazole glycerol phosphate synthase subunit HisF YP_002421542.1 2922789 D 440085 CDS YP_002421543.1 218530727 7113966 2923659..2924009 1 NC_011757.1 TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_2553 phosphoribosyl-ATP diphosphatase; phosphoribosyl-ATP diphosphatase 2924009 7113966 Mchl_2776 Methylobacterium extorquens CM4 phosphoribosyl-ATP diphosphatase YP_002421543.1 2923659 D 440085 CDS YP_002421544.1 218530728 7113967 2924006..2925019 1 NC_011757.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2925019 7113967 Mchl_2777 Methylobacterium extorquens CM4 pantothenate kinase YP_002421544.1 2924006 D 440085 CDS YP_002421545.1 218530729 7113968 complement(2925186..2926862) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_2555 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 2926862 7113968 Mchl_2778 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421545.1 2925186 R 440085 CDS YP_002421546.1 218530730 7113969 2927429..2928574 1 NC_011757.1 KEGG: mex:Mext_2556 hypothetical protein; hypothetical protein 2928574 7113969 Mchl_2779 Methylobacterium extorquens CM4 hypothetical protein YP_002421546.1 2927429 D 440085 CDS YP_002421547.1 218530731 7113970 2928766..2929287 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_2557 response regulator receiver; response regulator receiver protein 2929287 7113970 Mchl_2780 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421547.1 2928766 D 440085 CDS YP_002421548.1 218530732 7113971 2930057..2930728 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2558 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 2930728 7113971 Mchl_2781 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421548.1 2930057 D 440085 CDS YP_002421549.1 218530733 7113972 complement(2930849..2931175) 1 NC_011757.1 KEGG: mex:Mext_2559 hypothetical protein; hypothetical protein 2931175 7113972 Mchl_2782 Methylobacterium extorquens CM4 hypothetical protein YP_002421549.1 2930849 R 440085 CDS YP_002421550.1 218530734 7113973 complement(2931383..2931859) 1 NC_011757.1 TIGRFAM: phasin; PFAM: Phasin 2 family protein; KEGG: mex:Mext_2560 phasin; phasin 2931859 7113973 Mchl_2783 Methylobacterium extorquens CM4 phasin YP_002421550.1 2931383 R 440085 CDS YP_002421551.1 218530735 7113974 2932101..2934626 1 NC_011757.1 KEGG: mex:Mext_2561 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 2934626 7113974 Mchl_2784 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002421551.1 2932101 D 440085 CDS YP_002421552.1 218530736 7113975 2934886..2936844 1 NC_011757.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 2936844 7113975 Mchl_2785 Methylobacterium extorquens CM4 acetyl-CoA synthetase YP_002421552.1 2934886 D 440085 CDS YP_002421553.1 218530737 7113976 2937019..2937405 1 NC_011757.1 PFAM: protein of unknown function DUF485; KEGG: mex:Mext_2563 hypothetical protein; hypothetical protein 2937405 7113976 Mchl_2786 Methylobacterium extorquens CM4 hypothetical protein YP_002421553.1 2937019 D 440085 CDS YP_002421554.1 218530738 7113977 2937402..2939087 1 NC_011757.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: mex:Mext_2564 SSS family solute/sodium (Na+) symporter; SSS sodium solute transporter superfamily protein 2939087 7113977 Mchl_2787 Methylobacterium extorquens CM4 SSS sodium solute transporter superfamily protein YP_002421554.1 2937402 D 440085 CDS YP_002421555.1 218530739 7113978 2939346..2941082 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: mex:Mext_2565 major facilitator transporter; major facilitator superfamily protein 2941082 7113978 Mchl_2788 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002421555.1 2939346 D 440085 CDS YP_002421556.1 218530740 7114856 complement(2941296..2942894) 1 NC_011757.1 KEGG: mex:Mext_2566 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2942894 7114856 Mchl_2789 Methylobacterium extorquens CM4 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002421556.1 2941296 R 440085 CDS YP_002421557.1 218530741 7115019 complement(2943103..2944815) 1 NC_011757.1 PFAM: Heparinase II/III; KEGG: mex:Mext_2567 heparinase II/III family protein; Heparinase II/III 2944815 7115019 Mchl_2790 Methylobacterium extorquens CM4 Heparinase II/III YP_002421557.1 2943103 R 440085 CDS YP_002421558.1 218530742 7115020 complement(2945003..2945851) 1 NC_011757.1 PFAM: rhodanese; KEGG: mex:Mext_2568 rhodanese; rhodanese 2945851 7115020 Mchl_2791 Methylobacterium extorquens CM4 rhodanese YP_002421558.1 2945003 R 440085 CDS YP_002421559.1 218530743 7115021 2946124..2946360 1 NC_011757.1 KEGG: mex:Mext_2569 hypothetical protein; hypothetical protein 2946360 7115021 Mchl_2792 Methylobacterium extorquens CM4 hypothetical protein YP_002421559.1 2946124 D 440085 CDS YP_002421560.1 218530744 7115022 complement(2946471..2947556) 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_2570 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 2947556 7115022 Mchl_2793 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002421560.1 2946471 R 440085 CDS YP_002421561.1 218530745 7115023 2948216..2949748 1 NC_011757.1 PFAM: helicase; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: mex:Mext_2571 DEAD/DEAH box helicase domain-containing protein; DEAD/DEAH box helicase 2949748 7115023 Mchl_2794 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002421561.1 2948216 D 440085 CDS YP_002421562.1 218530746 7115024 2949923..2950108 1 NC_011757.1 PFAM: protein of unknown function DUF1508; KEGG: mpo:Mpop_2504 protein of unknown function DUF1508; hypothetical protein 2950108 7115024 Mchl_2795 Methylobacterium extorquens CM4 hypothetical protein YP_002421562.1 2949923 D 440085 CDS YP_002421563.1 218530747 7115025 2950235..2950519 1 NC_011757.1 KEGG: mex:Mext_2573 hypothetical protein; hypothetical protein 2950519 7115025 Mchl_2796 Methylobacterium extorquens CM4 hypothetical protein YP_002421563.1 2950235 D 440085 CDS YP_002421564.1 218530748 7115026 2950729..2950872 1 NC_011757.1 KEGG: mpo:Mpop_2506 hypothetical protein; hypothetical protein 2950872 7115026 Mchl_2797 Methylobacterium extorquens CM4 hypothetical protein YP_002421564.1 2950729 D 440085 CDS YP_002421565.1 218530749 7115027 2950958..2951377 1 NC_011757.1 PFAM: thioesterase superfamily protein; KEGG: mex:Mext_2575 thioesterase superfamily protein; thioesterase superfamily protein 2951377 7115027 Mchl_2798 Methylobacterium extorquens CM4 thioesterase superfamily protein YP_002421565.1 2950958 D 440085 CDS YP_002421566.1 218530750 7115028 2951542..2952186 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_2576 beta-lactamase domain-containing protein; beta-lactamase 2952186 7115028 Mchl_2799 Methylobacterium extorquens CM4 beta-lactamase YP_002421566.1 2951542 D 440085 CDS YP_002421567.1 218530751 7115029 2952425..2954872 1 NC_011757.1 KEGG: mex:Mext_2577 DNA gyrase subunit beta; TIGRFAM: DNA gyrase subunit beta; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; DNA topoisomerase type IIsubunit alpha B region 2 domain protein; SMART: DNA topoisomerase II; DNA gyrase subunit beta 2954872 7115029 Mchl_2800 Methylobacterium extorquens CM4 DNA gyrase subunit beta YP_002421567.1 2952425 D 440085 CDS YP_002421568.1 218530752 7115030 complement(2954936..2955643) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_2578 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 2955643 7115030 Mchl_2801 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002421568.1 2954936 R 440085 CDS YP_002421569.1 218530753 7115031 2956083..2956508 1 NC_011757.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: mex:Mext_2579 large conductance mechanosensitive channel protein; large conductance mechanosensitive channel protein 2956508 7115031 Mchl_2802 Methylobacterium extorquens CM4 large conductance mechanosensitive channel protein YP_002421569.1 2956083 D 440085 CDS YP_002421570.1 218530754 7115032 complement(2956515..2956805) 1 NC_011757.1 KEGG: mex:Mext_2580 hypothetical protein; hypothetical protein 2956805 7115032 Mchl_2803 Methylobacterium extorquens CM4 hypothetical protein YP_002421570.1 2956515 R 440085 CDS YP_002421571.1 218530755 7115033 complement(2957097..2957510) 1 NC_011757.1 PFAM: protein of unknown function DUF1236; KEGG: mex:Mext_2581 hypothetical protein; hypothetical protein 2957510 7115033 Mchl_2804 Methylobacterium extorquens CM4 hypothetical protein YP_002421571.1 2957097 R 440085 CDS YP_002421572.1 218530756 7115034 complement(2957693..2958874) 1 NC_011757.1 PFAM: aminotransferase class I and II; KEGG: mex:Mext_2582 aminotransferase class I and II; class I and II aminotransferase 2958874 7115034 Mchl_2805 Methylobacterium extorquens CM4 class I and II aminotransferase YP_002421572.1 2957693 R 440085 CDS YP_002421573.1 218530757 7115035 complement(2958996..2959187) 1 NC_011757.1 KEGG: mex:Mext_2583 hypothetical protein; hypothetical protein 2959187 7115035 Mchl_2806 Methylobacterium extorquens CM4 hypothetical protein YP_002421573.1 2958996 R 440085 CDS YP_002421574.1 218530758 7115036 complement(2959355..2960761) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_2584 ATPase domain-containing protein; histidine kinase 2960761 7115036 Mchl_2807 Methylobacterium extorquens CM4 histidine kinase YP_002421574.1 2959355 R 440085 CDS YP_002421575.1 218530759 7115037 complement(2960769..2961497) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_2585 response regulator receiver; transcriptional regulator 2961497 7115037 Mchl_2808 Methylobacterium extorquens CM4 transcriptional regulator YP_002421575.1 2960769 R 440085 CDS YP_002421576.1 218530760 7115038 complement(2961497..2962072) 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_2586 regulatory protein MarR; MarR family transcriptional regulator 2962072 7115038 Mchl_2809 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002421576.1 2961497 R 440085 CDS YP_002421577.1 218530761 7115039 2962281..2963168 1 NC_011757.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2963168 7115039 Mchl_2810 Methylobacterium extorquens CM4 branched-chain amino acid aminotransferase YP_002421577.1 2962281 D 440085 CDS YP_002421578.1 218530762 7115040 2963271..2963534 1 NC_011757.1 KEGG: mex:Mext_2588 hypothetical protein; hypothetical protein 2963534 7115040 Mchl_2811 Methylobacterium extorquens CM4 hypothetical protein YP_002421578.1 2963271 D 440085 CDS YP_002421579.1 218530763 7115041 2963856..2964026 1 NC_011757.1 PFAM: Flp/Fap pilin component; KEGG: mpo:Mpop_2617 Flp/Fap pilin component; Flp/Fap pilin component 2964026 7115041 Mchl_2812 Methylobacterium extorquens CM4 Flp/Fap pilin component YP_002421579.1 2963856 D 440085 CDS YP_002421580.1 218530764 7115042 complement(2964174..2964944) 1 NC_011757.1 KEGG: mex:Mext_2590 hypothetical protein; hypothetical protein 2964944 7115042 Mchl_2813 Methylobacterium extorquens CM4 hypothetical protein YP_002421580.1 2964174 R 440085 CDS YP_002421581.1 218530765 7115043 complement(2965182..2966663) 1 NC_011757.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: mex:Mext_2591 multi anti extrusion protein MatE; multi antimicrobial extrusion protein MatE 2966663 7115043 Mchl_2814 Methylobacterium extorquens CM4 multi antimicrobial extrusion protein MatE YP_002421581.1 2965182 R 440085 CDS YP_002421582.1 218530766 7115044 complement(2966656..2968554) 1 NC_011757.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mex:Mext_2592 potassium efflux system protein; potassium efflux system protein 2968554 7115044 Mchl_2815 Methylobacterium extorquens CM4 potassium efflux system protein YP_002421582.1 2966656 R 440085 CDS YP_002421583.1 218530767 7115045 2968907..2969929 1 NC_011757.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2969929 ispH 7115045 ispH Methylobacterium extorquens CM4 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002421583.1 2968907 D 440085 CDS YP_002421584.1 218530768 7115046 2970004..2970993 1 NC_011757.1 KEGG: mex:Mext_2594 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; homoserine kinase 2970993 7115046 Mchl_2817 Methylobacterium extorquens CM4 homoserine kinase YP_002421584.1 2970004 D 440085 CDS YP_002421585.1 218530769 7115047 complement(2971042..2971524) 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: mex:Mext_2595 redoxin domain-containing protein; redoxin 2971524 7115047 Mchl_2818 Methylobacterium extorquens CM4 redoxin YP_002421585.1 2971042 R 440085 CDS YP_002421586.1 218530770 7115048 2971648..2972256 1 NC_011757.1 PFAM: protein of unknown function DUF179; KEGG: mex:Mext_2596 hypothetical protein; hypothetical protein 2972256 7115048 Mchl_2819 Methylobacterium extorquens CM4 hypothetical protein YP_002421586.1 2971648 D 440085 CDS YP_002421587.1 218530771 7115049 complement(2972295..2973371) 1 NC_011757.1 KEGG: mex:Mext_2597 hypothetical protein; hypothetical protein 2973371 7115049 Mchl_2820 Methylobacterium extorquens CM4 hypothetical protein YP_002421587.1 2972295 R 440085 CDS YP_002421588.1 218530772 7115050 complement(2973540..2976215) 1 NC_011757.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2976215 alaS 7115050 alaS Methylobacterium extorquens CM4 alanyl-tRNA synthetase YP_002421588.1 2973540 R 440085 CDS YP_002421589.1 218530773 7115051 complement(2976310..2977017) 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_2599 helix-turn-helix type 11 domain-containing protein; hypothetical protein 2977017 7115051 Mchl_2822 Methylobacterium extorquens CM4 hypothetical protein YP_002421589.1 2976310 R 440085 CDS YP_002421590.1 218530774 7115052 2977092..2977694 1 NC_011757.1 KEGG: mex:Mext_2600 glutathione S-transferase; glutathione S-transferase 2977694 7115052 Mchl_2823 Methylobacterium extorquens CM4 glutathione S-transferase YP_002421590.1 2977092 D 440085 CDS YP_002421591.1 218530775 7115053 complement(2977777..2978877) 1 NC_011757.1 KEGG: mex:Mext_2601 RecA protein; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: ATPase AAA; recA protein 2978877 7115053 Mchl_2824 Methylobacterium extorquens CM4 recA protein YP_002421591.1 2977777 R 440085 CDS YP_002421592.1 218530776 7115054 complement(2979133..2981844) 1 NC_011757.1 KEGG: mex:Mext_2602 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 2981844 7115054 Mchl_2825 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002421592.1 2979133 R 440085 CDS YP_002421593.1 218530777 7115055 complement(2982003..2983067) 1 NC_011757.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: mex:Mext_2603 flagellar biosynthetic protein FlhB; flagellar biosynthetic protein FlhB 2983067 7115055 Mchl_2826 Methylobacterium extorquens CM4 flagellar biosynthetic protein FlhB YP_002421593.1 2982003 R 440085 CDS YP_002421594.1 218530778 7115056 complement(2983170..2983946) 1 NC_011757.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: mex:Mext_2604 flagellar biosynthetic protein FliR; flagellar biosynthetic protein FliR 2983946 7115056 Mchl_2827 Methylobacterium extorquens CM4 flagellar biosynthetic protein FliR YP_002421594.1 2983170 R 440085 CDS YP_002421595.1 218530779 7115057 complement(2983992..2984258) 1 NC_011757.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: mex:Mext_2605 flagellar biosynthetic protein FliQ; flagellar biosynthetic protein FliQ 2984258 7115057 Mchl_2828 Methylobacterium extorquens CM4 flagellar biosynthetic protein FliQ YP_002421595.1 2983992 R 440085 CDS YP_002421596.1 218530780 7115058 complement(2984340..2984663) 1 NC_011757.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: mex:Mext_2606 flagellar hook-basal body complex subunit FliE; flagellar hook-basal body complex subunit FliE 2984663 7115058 Mchl_2829 Methylobacterium extorquens CM4 flagellar hook-basal body complex subunit FliE YP_002421596.1 2984340 R 440085 CDS YP_002421597.1 218530781 7115059 complement(2984669..2985079) 1 NC_011757.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 2985079 flgC 7115059 flgC Methylobacterium extorquens CM4 flagellar basal body rod protein FlgC YP_002421597.1 2984669 R 440085 CDS YP_002421598.1 218530782 7115060 complement(2985114..2985530) 1 NC_011757.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar basal body rod protein FlgB 2985530 flgB 7115060 flgB Methylobacterium extorquens CM4 flagellar basal body rod protein FlgB YP_002421598.1 2985114 R 440085 CDS YP_002421599.1 218530783 7115061 2985769..2987076 1 NC_011757.1 KEGG: mex:Mext_2609 hypothetical protein; hypothetical protein 2987076 7115061 Mchl_2832 Methylobacterium extorquens CM4 hypothetical protein YP_002421599.1 2985769 D 440085 CDS YP_002421600.1 218530784 7115062 2987184..2988278 1 NC_011757.1 PFAM: FAD dependent oxidoreductase; KEGG: mex:Mext_2610 FAD dependent oxidoreductase; FAD dependent oxidoreductase 2988278 7115062 Mchl_2833 Methylobacterium extorquens CM4 FAD dependent oxidoreductase YP_002421600.1 2987184 D 440085 CDS YP_002421601.1 218530785 7115063 complement(2988281..2989120) 1 NC_011757.1 PFAM: transglutaminase; KEGG: mex:Mext_2611 transglutaminase domain-containing protein; transglutaminase 2989120 7115063 Mchl_2834 Methylobacterium extorquens CM4 transglutaminase YP_002421601.1 2988281 R 440085 CDS YP_002421602.1 218530786 7115064 2989318..2990124 1 NC_011757.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome C assembly protein; KEGG: mex:Mext_2612 heme exporter protein CcmC; heme exporter protein CcmC 2990124 7115064 Mchl_2835 Methylobacterium extorquens CM4 heme exporter protein CcmC YP_002421602.1 2989318 D 440085 CDS YP_002421603.1 218530787 7115065 2990262..2990414 1 NC_011757.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: mex:Mext_2613 heme exporter protein CcmD; heme exporter protein CcmD 2990414 7115065 Mchl_2836 Methylobacterium extorquens CM4 heme exporter protein CcmD YP_002421603.1 2990262 D 440085 CDS YP_002421604.1 218530788 7115066 2990411..2991031 1 NC_011757.1 TIGRFAM: periplasmic protein thiol/disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; thioredoxin domain; KEGG: mex:Mext_2614 periplasmic protein thiol--disulphide oxidoreductase DsbE; periplasmic protein thiol/disulfide oxidoreductase DsbE 2991031 7115066 Mchl_2837 Methylobacterium extorquens CM4 periplasmic protein thiol/disulfide oxidoreductase DsbE YP_002421604.1 2990411 D 440085 CDS YP_002421605.1 218530789 7115067 2991154..2991897 1 NC_011757.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: mex:Mext_2615 hypothetical protein; hypothetical protein 2991897 7115067 Mchl_2838 Methylobacterium extorquens CM4 hypothetical protein YP_002421605.1 2991154 D 440085 CDS YP_002421606.1 218530790 7115068 2991894..2993468 1 NC_011757.1 PFAM: protein of unknown function DUF162; KEGG: mex:Mext_2616 hypothetical protein; hypothetical protein 2993468 7115068 Mchl_2839 Methylobacterium extorquens CM4 hypothetical protein YP_002421606.1 2991894 D 440085 CDS YP_002421607.1 218530791 7115069 2993465..2994070 1 NC_011757.1 PFAM: protein of unknown function DUF162; KEGG: mex:Mext_2617 hypothetical protein; hypothetical protein 2994070 7115069 Mchl_2840 Methylobacterium extorquens CM4 hypothetical protein YP_002421607.1 2993465 D 440085 CDS YP_002421608.1 218530792 7115070 2994157..2995017 1 NC_011757.1 PFAM: transglutaminase; KEGG: mex:Mext_2618 transglutaminase domain-containing protein; transglutaminase 2995017 7115070 Mchl_2841 Methylobacterium extorquens CM4 transglutaminase YP_002421608.1 2994157 D 440085 CDS YP_002421609.1 218530793 7115071 2995432..2995893 1 NC_011757.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2995893 rplM 7115071 rplM Methylobacterium extorquens CM4 50S ribosomal protein L13 YP_002421609.1 2995432 D 440085 CDS YP_002421610.1 218530794 7115072 2995896..2996381 1 NC_011757.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2996381 rpsI 7115072 rpsI Methylobacterium extorquens CM4 30S ribosomal protein S9 YP_002421610.1 2995896 D 440085 CDS YP_002421611.1 218530795 7115073 2996464..2996838 1 NC_011757.1 KEGG: mex:Mext_2621 hypothetical protein; hypothetical protein 2996838 7115073 Mchl_2844 Methylobacterium extorquens CM4 hypothetical protein YP_002421611.1 2996464 D 440085 CDS YP_002421612.1 218530796 7115074 2996920..2997129 1 NC_011757.1 PFAM: TOBE domain protein; KEGG: mex:Mext_2622 TOBE domain-containing protein; TOBE domain-containing protein 2997129 7115074 Mchl_2845 Methylobacterium extorquens CM4 TOBE domain-containing protein YP_002421612.1 2996920 D 440085 CDS YP_002421613.1 218530797 7115075 complement(2997142..2998020) 1 NC_011757.1 PFAM: aldose 1-epimerase; KEGG: mex:Mext_2623 aldose 1-epimerase; aldose 1-epimerase 2998020 7115075 Mchl_2846 Methylobacterium extorquens CM4 aldose 1-epimerase YP_002421613.1 2997142 R 440085 CDS YP_002421614.1 218530798 7115076 complement(2998083..2999843) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_2624 ABC transporter; ABC transporter 2999843 7115076 Mchl_2847 Methylobacterium extorquens CM4 ABC transporter YP_002421614.1 2998083 R 440085 CDS YP_002421615.1 218530799 7115077 3000253..3000726 1 NC_011757.1 KEGG: mex:Mext_2625 hypothetical protein; hypothetical protein 3000726 7115077 Mchl_2848 Methylobacterium extorquens CM4 hypothetical protein YP_002421615.1 3000253 D 440085 CDS YP_002421616.1 218530800 7115078 3000856..3000954 1 NC_011757.1 KEGG: mpo:Mpop_2656 hypothetical protein; hypothetical protein 3000954 7115078 Mchl_2849 Methylobacterium extorquens CM4 hypothetical protein YP_002421616.1 3000856 D 440085 CDS YP_002421617.1 218530801 7115079 3001577..3001999 1 NC_011757.1 KEGG: mex:Mext_2626 hypothetical protein; hypothetical protein 3001999 7115079 Mchl_2850 Methylobacterium extorquens CM4 hypothetical protein YP_002421617.1 3001577 D 440085 CDS YP_002421618.1 218530802 7115081 complement(3002576..3002794) 1 NC_011757.1 PFAM: protein of unknown function DUF329; KEGG: mex:Mext_2627 hypothetical protein; hypothetical protein 3002794 7115081 Mchl_2851 Methylobacterium extorquens CM4 hypothetical protein YP_002421618.1 3002576 R 440085 CDS YP_002421619.1 218530803 7115082 complement(3002791..3003462) 1 NC_011757.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: mex:Mext_2628 maf protein; maf protein 3003462 7115082 Mchl_2852 Methylobacterium extorquens CM4 maf protein YP_002421619.1 3002791 R 440085 CDS YP_002421620.1 218530804 7115084 complement(3003762..3004070) 1 NC_011757.1 KEGG: mex:Mext_2629 hypothetical protein; hypothetical protein 3004070 7115084 Mchl_2853 Methylobacterium extorquens CM4 hypothetical protein YP_002421620.1 3003762 R 440085 CDS YP_002421621.1 218530805 7115085 complement(3004270..3004560) 1 NC_011757.1 KEGG: mex:Mext_2630 hypothetical protein; hypothetical protein 3004560 7115085 Mchl_2854 Methylobacterium extorquens CM4 hypothetical protein YP_002421621.1 3004270 R 440085 CDS YP_002421622.1 218530806 7115086 complement(3004725..3006968) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2631 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 3006968 7115086 Mchl_2855 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002421622.1 3004725 R 440085 CDS YP_002421623.1 218530807 7115087 3007654..3007785 1 NC_011757.1 KEGG: mpo:Mpop_2755 hypothetical protein; hypothetical protein 3007785 7115087 Mchl_2856 Methylobacterium extorquens CM4 hypothetical protein YP_002421623.1 3007654 D 440085 CDS YP_002421624.1 218530808 7115088 3007879..3008298 1 NC_011757.1 KEGG: mex:Mext_2632 hypothetical protein; hypothetical protein 3008298 7115088 Mchl_2857 Methylobacterium extorquens CM4 hypothetical protein YP_002421624.1 3007879 D 440085 CDS YP_002421625.1 218530809 7115089 3008429..3008692 1 NC_011757.1 KEGG: mex:Mext_2633 hypothetical protein; hypothetical protein 3008692 7115089 Mchl_2858 Methylobacterium extorquens CM4 hypothetical protein YP_002421625.1 3008429 D 440085 CDS YP_002421626.1 218530810 7115090 complement(3008736..3009401) 1 NC_011757.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: mex:Mext_2634 heme exporter protein CcmB; heme exporter protein CcmB 3009401 7115090 Mchl_2859 Methylobacterium extorquens CM4 heme exporter protein CcmB YP_002421626.1 3008736 R 440085 CDS YP_002421627.1 218530811 7115091 complement(3009401..3010048) 1 NC_011757.1 KEGG: mex:Mext_2635 heme exporter protein CcmA; TIGRFAM: heme exporter protein CcmA; PFAM: ABC transporter; SMART: ATPase AAA; heme exporter protein CcmA 3010048 7115091 Mchl_2860 Methylobacterium extorquens CM4 heme exporter protein CcmA YP_002421627.1 3009401 R 440085 CDS YP_002421628.1 218530812 7115092 3010266..3010463 1 NC_011757.1 KEGG: mex:Mext_2636 hypothetical protein; hypothetical protein 3010463 7115092 Mchl_2861 Methylobacterium extorquens CM4 hypothetical protein YP_002421628.1 3010266 D 440085 CDS YP_002421629.1 218530813 7115093 3010770..3013469 1 NC_011757.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: mex:Mext_2637 aconitate hydratase 1; aconitate hydratase 1 3013469 7115093 Mchl_2862 Methylobacterium extorquens CM4 aconitate hydratase 1 YP_002421629.1 3010770 D 440085 CDS YP_002421630.1 218530814 7115094 3013522..3013956 1 NC_011757.1 hypothetical protein 3013956 7115094 Mchl_2863 Methylobacterium extorquens CM4 hypothetical protein YP_002421630.1 3013522 D 440085 CDS YP_002421631.1 218530815 7115095 3014065..3014364 1 NC_011757.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: mex:Mext_2638 antibiotic biosynthesis monooxygenase; antibiotic biosynthesis monooxygenase 3014364 7115095 Mchl_2864 Methylobacterium extorquens CM4 antibiotic biosynthesis monooxygenase YP_002421631.1 3014065 D 440085 CDS YP_002421632.1 218530816 7115096 3014493..3015134 1 NC_011757.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: glutathione S-transferase domain; KEGG: mex:Mext_2639 maleylacetoacetate isomerase; maleylacetoacetate isomerase 3015134 7115096 Mchl_2865 Methylobacterium extorquens CM4 maleylacetoacetate isomerase YP_002421632.1 3014493 D 440085 CDS YP_002421633.1 218530817 7115097 3015291..3016622 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_2640 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 3016622 7115097 Mchl_2866 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002421633.1 3015291 D 440085 CDS YP_002421634.1 218530818 7115098 3016708..3017034 1 NC_011757.1 PFAM: ethyl tert-butyl ether degradation EthD; KEGG: mex:Mext_2641 ethyl tert-butyl ether degradation EthD; ethyl tert-butyl ether degradation EthD 3017034 7115098 Mchl_2867 Methylobacterium extorquens CM4 ethyl tert-butyl ether degradation EthD YP_002421634.1 3016708 D 440085 CDS YP_002421635.1 218530819 7115099 3017034..3017345 1 NC_011757.1 KEGG: mex:Mext_2642 hypothetical protein; hypothetical protein 3017345 7115099 Mchl_2868 Methylobacterium extorquens CM4 hypothetical protein YP_002421635.1 3017034 D 440085 CDS YP_002421636.1 218530820 7115674 complement(3017426..3018799) 1 NC_011757.1 PFAM: chemotaxis sensory transducer; KEGG: mex:Mext_2643 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3018799 7115674 Mchl_2869 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421636.1 3017426 R 440085 CDS YP_002421637.1 218530821 7115677 3019178..3020251 1 NC_011757.1 KEGG: mex:Mext_2644 quinolinate synthetase complex, A subunit; TIGRFAM: quinolinate synthetase complex, subunit alpha; PFAM: Quinolinate synthetase A; quinolinate synthetase complex subunit alpha 3020251 7115677 Mchl_2870 Methylobacterium extorquens CM4 quinolinate synthetase complex subunit alpha YP_002421637.1 3019178 D 440085 CDS YP_002421638.1 218530822 7115678 3020251..3021780 1 NC_011757.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mex:Mext_2645 L-aspartate oxidase; L-aspartate oxidase 3021780 7115678 Mchl_2871 Methylobacterium extorquens CM4 L-aspartate oxidase YP_002421638.1 3020251 D 440085 CDS YP_002421639.1 218530823 7115679 3021773..3022633 1 NC_011757.1 KEGG: mex:Mext_2646 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; nicotinate-nucleotide pyrophosphorylase 3022633 7115679 Mchl_2872 Methylobacterium extorquens CM4 nicotinate-nucleotide pyrophosphorylase YP_002421639.1 3021773 D 440085 CDS YP_002421640.1 218530824 7115680 3022949..3023617 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2647 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3023617 7115680 Mchl_2873 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421640.1 3022949 D 440085 CDS YP_002421641.1 218530825 7115681 complement(3023717..3023854) 1 NC_011757.1 KEGG: mpo:Mpop_2771 hypothetical protein; hypothetical protein 3023854 7115681 Mchl_2874 Methylobacterium extorquens CM4 hypothetical protein YP_002421641.1 3023717 R 440085 CDS YP_002421642.1 218530826 7115682 3024008..3024250 1 NC_011757.1 KEGG: mex:Mext_2648 hypothetical protein; hypothetical protein 3024250 7115682 Mchl_2875 Methylobacterium extorquens CM4 hypothetical protein YP_002421642.1 3024008 D 440085 CDS YP_002421643.1 218530827 7115683 complement(3024590..3025018) 1 NC_011757.1 PFAM: protein of unknown function DUF971; KEGG: mex:Mext_2649 hypothetical protein; hypothetical protein 3025018 7115683 Mchl_2876 Methylobacterium extorquens CM4 hypothetical protein YP_002421643.1 3024590 R 440085 CDS YP_002421644.1 218530828 7115684 3025162..3026196 1 NC_011757.1 KEGG: mex:Mext_2650 molybdenum cofactor biosynthesis protein A; TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: radical SAM domain protein; molybdenum cofactor synthesis protein; SMART: Elongator protein 3/MiaB/NifB; molybdenum cofactor biosynthesis protein A 3026196 7115684 Mchl_2877 Methylobacterium extorquens CM4 molybdenum cofactor biosynthesis protein A YP_002421644.1 3025162 D 440085 CDS YP_002421645.1 218530829 7115685 complement(3026203..3027123) 1 NC_011757.1 KEGG: mex:Mext_2651 hypothetical protein; hypothetical protein 3027123 7115685 Mchl_2878 Methylobacterium extorquens CM4 hypothetical protein YP_002421645.1 3026203 R 440085 CDS YP_002421646.1 218530830 7115686 complement(3027024..3028220) 1 NC_011757.1 PFAM: GSCFA domain protein; KEGG: mex:Mext_2652 GSCFA domain-containing protein; GSCFA domain-containing protein 3028220 7115686 Mchl_2879 Methylobacterium extorquens CM4 GSCFA domain-containing protein YP_002421646.1 3027024 R 440085 CDS YP_002421647.1 218530831 7115687 3028415..3029281 1 NC_011757.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mex:Mext_2653 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase 3029281 7115687 Mchl_2880 Methylobacterium extorquens CM4 6-phosphogluconate dehydrogenase YP_002421647.1 3028415 D 440085 CDS YP_002421648.1 218530832 7115688 complement(3029259..3030212) 1 NC_011757.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 3030212 miaA 7115688 miaA Methylobacterium extorquens CM4 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002421648.1 3029259 R 440085 CDS YP_002421649.1 218530833 7115689 3030224..3031120 1 NC_011757.1 KEGG: mex:Mext_2655 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; phosphoserine phosphatase SerB 3031120 7115689 Mchl_2882 Methylobacterium extorquens CM4 phosphoserine phosphatase SerB YP_002421649.1 3030224 D 440085 CDS YP_002421650.1 218530834 7115690 complement(3031229..3032764) 1 NC_011757.1 KEGG: mex:Mext_2656 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 3032764 7115690 Mchl_2883 Methylobacterium extorquens CM4 protease Do YP_002421650.1 3031229 R 440085 CDS YP_002421651.1 218530835 7115691 complement(3032876..3033817) 1 NC_011757.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: mex:Mext_2657 HflC protein; HflC protein 3033817 7115691 Mchl_2884 Methylobacterium extorquens CM4 HflC protein YP_002421651.1 3032876 R 440085 CDS YP_002421652.1 218530836 7115692 complement(3033814..3034962) 1 NC_011757.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: mex:Mext_2658 HflK protein; HflK protein 3034962 7115692 Mchl_2885 Methylobacterium extorquens CM4 HflK protein YP_002421652.1 3033814 R 440085 CDS YP_002421653.1 218530837 7115693 complement(3035255..3035755) 1 NC_011757.1 PFAM: dihydrofolate reductase region; KEGG: mex:Mext_2659 dihydrofolate reductase; dihydrofolate reductase 3035755 7115693 Mchl_2886 Methylobacterium extorquens CM4 dihydrofolate reductase YP_002421653.1 3035255 R 440085 CDS YP_002421654.1 218530838 7115694 complement(3035755..3036549) 1 NC_011757.1 PFAM: thymidylate synthase; KEGG: mex:Mext_2660 thymidylate synthase; Thymidylate synthase 3036549 7115694 Mchl_2887 Methylobacterium extorquens CM4 Thymidylate synthase YP_002421654.1 3035755 R 440085 CDS YP_002421655.1 218530839 7115695 complement(3036637..3037455) 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_2661 abortive infection protein; hypothetical protein 3037455 7115695 Mchl_2888 Methylobacterium extorquens CM4 hypothetical protein YP_002421655.1 3036637 R 440085 CDS YP_002421656.1 218530840 7115696 3037933..3038586 1 NC_011757.1 PFAM: protein of unknown function DUF1321; KEGG: mex:Mext_2662 hypothetical protein; hypothetical protein 3038586 7115696 Mchl_2889 Methylobacterium extorquens CM4 hypothetical protein YP_002421656.1 3037933 D 440085 CDS YP_002421657.1 218530841 7115697 complement(3038637..3040037) 1 NC_011757.1 PFAM: cytochrome P450; KEGG: mex:Mext_2663 cytochrome P450; cytochrome P450 3040037 7115697 Mchl_2890 Methylobacterium extorquens CM4 cytochrome P450 YP_002421657.1 3038637 R 440085 CDS YP_002421658.1 218530842 7115698 3040163..3041581 1 NC_011757.1 TIGRFAM: fumarate hydratase, class II; PFAM: fumarate lyase; fumarate hydratase class II; KEGG: mex:Mext_2664 fumarate hydratase, class II; fumarate hydratase, class II 3041581 7115698 Mchl_2891 Methylobacterium extorquens CM4 fumarate hydratase, class II YP_002421658.1 3040163 D 440085 CDS YP_002421659.1 218530843 7115699 3041642..3041830 1 NC_011757.1 KEGG: mex:Mext_2665 hypothetical protein; hypothetical protein 3041830 7115699 Mchl_2892 Methylobacterium extorquens CM4 hypothetical protein YP_002421659.1 3041642 D 440085 CDS YP_002421660.1 218530844 7115700 3041827..3042138 1 NC_011757.1 KEGG: mpo:Mpop_2788 hypothetical protein; hypothetical protein 3042138 7115700 Mchl_2893 Methylobacterium extorquens CM4 hypothetical protein YP_002421660.1 3041827 D 440085 CDS YP_002421661.1 218530845 7115701 complement(3042061..3042546) 1 NC_011757.1 PFAM: protein of unknown function DUF1052; KEGG: mex:Mext_2667 hypothetical protein; hypothetical protein 3042546 7115701 Mchl_2894 Methylobacterium extorquens CM4 hypothetical protein YP_002421661.1 3042061 R 440085 CDS YP_002421662.1 218530846 7115702 complement(3042616..3043410) 1 NC_011757.1 PFAM: periplasmic binding protein; KEGG: mex:Mext_2668 periplasmic binding protein; periplasmic binding protein 3043410 7115702 Mchl_2895 Methylobacterium extorquens CM4 periplasmic binding protein YP_002421662.1 3042616 R 440085 CDS YP_002421663.1 218530847 7115703 complement(3043417..3043938) 1 NC_011757.1 KEGG: mex:Mext_2669 hypothetical protein; hypothetical protein 3043938 7115703 Mchl_2896 Methylobacterium extorquens CM4 hypothetical protein YP_002421663.1 3043417 R 440085 CDS YP_002421664.1 218530848 7115704 3044157..3045008 1 NC_011757.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 3045008 7115704 Mchl_2897 Methylobacterium extorquens CM4 pyridoxamine kinase YP_002421664.1 3044157 D 440085 CDS YP_002421665.1 218530849 7115705 3045028..3045957 1 NC_011757.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: mex:Mext_2671 PhzF family phenazine biosynthesis protein; phenazine biosynthesis protein PhzF family 3045957 7115705 Mchl_2898 Methylobacterium extorquens CM4 phenazine biosynthesis protein PhzF family YP_002421665.1 3045028 D 440085 CDS YP_002421666.1 218530850 7115706 3045947..3046678 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_2672 NUDIX hydrolase; NUDIX hydrolase 3046678 7115706 Mchl_2899 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002421666.1 3045947 D 440085 CDS YP_002421667.1 218530851 7115707 complement(3046697..3047023) 1 NC_011757.1 KEGG: mex:Mext_2673 hypothetical protein; hypothetical protein 3047023 7115707 Mchl_2900 Methylobacterium extorquens CM4 hypothetical protein YP_002421667.1 3046697 R 440085 CDS YP_002421668.1 218530852 7115708 3047447..3049009 1 NC_011757.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 3049009 7115708 Mchl_2901 Methylobacterium extorquens CM4 2-isopropylmalate synthase YP_002421668.1 3047447 D 440085 CDS YP_002421669.1 218530853 7115709 3049201..3051036 1 NC_011757.1 KEGG: mex:Mext_2675 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; dihydroxy-acid dehydratase 3051036 7115709 Mchl_2902 Methylobacterium extorquens CM4 dihydroxy-acid dehydratase YP_002421669.1 3049201 D 440085 CDS YP_002421670.1 218530854 7115710 3051199..3052209 1 NC_011757.1 PFAM: protein of unknown function DUF1611; KEGG: mex:Mext_2676 hypothetical protein; hypothetical protein 3052209 7115710 Mchl_2903 Methylobacterium extorquens CM4 hypothetical protein YP_002421670.1 3051199 D 440085 CDS YP_002421671.1 218530855 7115711 3052223..3053203 1 NC_011757.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein; mandelate racemase/muconate lactonizing protein 3053203 7115711 Mchl_2904 Methylobacterium extorquens CM4 mandelate racemase/muconate lactonizing protein YP_002421671.1 3052223 D 440085 CDS YP_002421672.1 218530856 7115712 complement(3053213..3054331) 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mex:Mext_2678 lytic transglycosylase catalytic; lytic transglycosylase 3054331 7115712 Mchl_2905 Methylobacterium extorquens CM4 lytic transglycosylase YP_002421672.1 3053213 R 440085 CDS YP_002421673.1 218530857 7115713 3054647..3055840 1 NC_011757.1 PFAM: myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase GAPDH domain protein; KEGG: mex:Mext_2679 inositol-3-phosphate synthase; inositol-3-phosphate synthase 3055840 7115713 Mchl_2906 Methylobacterium extorquens CM4 inositol-3-phosphate synthase YP_002421673.1 3054647 D 440085 CDS YP_002421674.1 218530858 7115714 3055853..3056773 1 NC_011757.1 KEGG: mex:Mext_2680 hypothetical protein; hypothetical protein 3056773 7115714 Mchl_2907 Methylobacterium extorquens CM4 hypothetical protein YP_002421674.1 3055853 D 440085 CDS YP_002421675.1 218530859 7115715 3056805..3057986 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_2681 methyltransferase type 11; type 11 methyltransferase 3057986 7115715 Mchl_2908 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002421675.1 3056805 D 440085 CDS YP_002421676.1 218530860 7115716 3057986..3059014 1 NC_011757.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: mex:Mext_2682 oxidoreductase domain-containing protein; oxidoreductase domain-containing protein 3059014 7115716 Mchl_2909 Methylobacterium extorquens CM4 oxidoreductase domain-containing protein YP_002421676.1 3057986 D 440085 CDS YP_002421677.1 218530861 7115717 3059207..3060826 1 NC_011757.1 PFAM: protein of unknown function DUF181; KEGG: mex:Mext_2683 hypothetical protein; hypothetical protein 3060826 7115717 Mchl_2910 Methylobacterium extorquens CM4 hypothetical protein YP_002421677.1 3059207 D 440085 CDS YP_002421678.1 218530862 7115718 3060823..3061716 1 NC_011757.1 PFAM: xylose isomerase; KEGG: mex:Mext_2684 xylose isomerase domain-containing protein; xylose isomerase 3061716 7115718 Mchl_2911 Methylobacterium extorquens CM4 xylose isomerase YP_002421678.1 3060823 D 440085 CDS YP_002421679.1 218530863 7115719 3061713..3062951 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_2685 glycosyl transferase group 1; group 1 glycosyl transferase 3062951 7115719 Mchl_2912 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002421679.1 3061713 D 440085 CDS YP_002421680.1 218530864 7115720 3062948..3063709 1 NC_011757.1 PFAM: LmbE family protein; KEGG: mex:Mext_2686 LmbE family protein; LmbE family protein 3063709 7115720 Mchl_2913 Methylobacterium extorquens CM4 LmbE family protein YP_002421680.1 3062948 D 440085 CDS YP_002421681.1 218530865 7115721 3063693..3064319 1 NC_011757.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: mex:Mext_2687 uracil-DNA glycosylase superfamily protein; uracil-DNA glycosylase superfamily protein 3064319 7115721 Mchl_2914 Methylobacterium extorquens CM4 uracil-DNA glycosylase superfamily protein YP_002421681.1 3063693 D 440085 CDS YP_002421682.1 218530866 7115722 3064531..3065562 1 NC_011757.1 KEGG: mex:Mext_2688 hypothetical protein; hypothetical protein 3065562 7115722 Mchl_2915 Methylobacterium extorquens CM4 hypothetical protein YP_002421682.1 3064531 D 440085 CDS YP_002421683.1 218530867 7115723 3065586..3066878 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; KEGG: mex:Mext_2689 histidine kinase; PAS/PAC sensor signal transduction histidine kinase 3066878 7115723 Mchl_2916 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002421683.1 3065586 D 440085 CDS YP_002421684.1 218530868 7115724 3067080..3069578 1 NC_011757.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: mex:Mext_2690 ATPase P; ATPase P 3069578 7115724 Mchl_2917 Methylobacterium extorquens CM4 ATPase P YP_002421684.1 3067080 D 440085 CDS YP_002421685.1 218530869 7115725 3069575..3070039 1 NC_011757.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: mex:Mext_2691 Cu(I)-responsive transcriptional regulator; MerR family transcriptional regulator 3070039 7115725 Mchl_2918 Methylobacterium extorquens CM4 MerR family transcriptional regulator YP_002421685.1 3069575 D 440085 CDS YP_002421686.1 218530870 7115726 3070127..3071293 1 NC_011757.1 KEGG: mex:Mext_2692 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; amidohydrolase 3071293 7115726 Mchl_2919 Methylobacterium extorquens CM4 amidohydrolase YP_002421686.1 3070127 D 440085 CDS YP_002421687.1 218530871 7115727 complement(3071348..3073027) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mpo:Mpop_2816 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3073027 7115727 Mchl_2920 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421687.1 3071348 R 440085 CDS YP_002421688.1 218530872 7115728 complement(3073189..3074214) 1 NC_011757.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; KEGG: mex:Mext_2695 tRNA pseudouridine synthase B; tRNA pseudouridine synthase B 3074214 7115728 Mchl_2921 Methylobacterium extorquens CM4 tRNA pseudouridine synthase B YP_002421688.1 3073189 R 440085 CDS YP_002421689.1 218530873 7115729 complement(3074423..3074860) 1 NC_011757.1 PFAM: ribosome-binding factor A; KEGG: mex:Mext_2696 ribosome-binding factor A; ribosome-binding factor A 3074860 7115729 Mchl_2922 Methylobacterium extorquens CM4 ribosome-binding factor A YP_002421689.1 3074423 R 440085 CDS YP_002421690.1 218530874 7115730 complement(3074963..3077932) 1 NC_011757.1 TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; GTP-binding protein HSR1-related; elongation factor Tu domain 2 protein; translation initiation factor IF-2 domain protein; Initiation factor 2 associated domain protein ; Miro domain protein; KEGG: mex:Mext_2697 translation initiation factor IF-2; translation initiation factor IF-2 3077932 7115730 Mchl_2923 Methylobacterium extorquens CM4 translation initiation factor IF-2 YP_002421690.1 3074963 R 440085 CDS YP_002421691.1 218530875 7115731 complement(3077997..3078740) 1 NC_011757.1 PFAM: protein of unknown function DUF448; KEGG: mex:Mext_2698 hypothetical protein; hypothetical protein 3078740 7115731 Mchl_2924 Methylobacterium extorquens CM4 hypothetical protein YP_002421691.1 3077997 R 440085 CDS YP_002421692.1 218530876 7115732 complement(3078782..3080419) 1 NC_011757.1 KEGG: mex:Mext_2699 transcription termination factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: RNA binding S1 domain protein; KH type 1 domain protein; NusA domain protein; SMART: KH domain protein; NusA antitermination factor 3080419 7115732 Mchl_2925 Methylobacterium extorquens CM4 NusA antitermination factor YP_002421692.1 3078782 R 440085 CDS YP_002421693.1 218530877 7115733 complement(3080533..3081288) 1 NC_011757.1 PFAM: protein of unknown function DUF150; KEGG: mex:Mext_2700 hypothetical protein; hypothetical protein 3081288 7115733 Mchl_2926 Methylobacterium extorquens CM4 hypothetical protein YP_002421693.1 3080533 R 440085 CDS YP_002421694.1 218530878 7115734 3081554..3082207 1 NC_011757.1 KEGG: mex:Mext_2701 streptogramin A acetyltransferase; streptogramin A acetyltransferase 3082207 7115734 Mchl_2927 Methylobacterium extorquens CM4 streptogramin A acetyltransferase YP_002421694.1 3081554 D 440085 CDS YP_002421695.1 218530879 7115735 complement(3082144..3082320) 1 NC_011757.1 hypothetical protein 3082320 7115735 Mchl_2928 Methylobacterium extorquens CM4 hypothetical protein YP_002421695.1 3082144 R 440085 CDS YP_002421696.1 218530880 7115736 complement(3082535..3083569) 1 NC_011757.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase NAD - binding; semialdehyde dehydrogenase dimerisation region; KEGG: mex:Mext_2702 aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 3083569 7115736 Mchl_2929 Methylobacterium extorquens CM4 aspartate-semialdehyde dehydrogenase YP_002421696.1 3082535 R 440085 CDS YP_002421697.1 218530881 7115737 3083936..3084778 1 NC_011757.1 KEGG: mex:Mext_2703 hypothetical protein; hypothetical protein 3084778 7115737 Mchl_2930 Methylobacterium extorquens CM4 hypothetical protein YP_002421697.1 3083936 D 440085 CDS YP_002421698.1 218530882 7115738 3084892..3085305 1 NC_011757.1 KEGG: mex:Mext_2704 hypothetical protein; hypothetical protein 3085305 7115738 Mchl_2931 Methylobacterium extorquens CM4 hypothetical protein YP_002421698.1 3084892 D 440085 CDS YP_002421699.1 218530883 7115739 complement(3085369..3085917) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_2705 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 3085917 7115739 Mchl_2932 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002421699.1 3085369 R 440085 CDS YP_002421700.1 218530884 7115740 complement(3086001..3086294) 1 NC_011757.1 KEGG: mex:Mext_2706 hypothetical protein; hypothetical protein 3086294 7115740 Mchl_2933 Methylobacterium extorquens CM4 hypothetical protein YP_002421700.1 3086001 R 440085 CDS YP_002421701.1 218530885 7115741 complement(3086413..3087633) 1 NC_011757.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: mex:Mext_2707 cobalamin synthesis protein P47K; cobalamin synthesis protein P47K 3087633 7115741 Mchl_2934 Methylobacterium extorquens CM4 cobalamin synthesis protein P47K YP_002421701.1 3086413 R 440085 CDS YP_002421702.1 218530886 7115742 3087859..3088485 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_2708 regulatory protein TetR; TetR family transcriptional regulator 3088485 7115742 Mchl_2935 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002421702.1 3087859 D 440085 CDS YP_002421703.1 218530887 7115743 3088652..3089131 1 NC_011757.1 KEGG: mex:Mext_2709 hypothetical protein; hypothetical protein 3089131 7115743 Mchl_2936 Methylobacterium extorquens CM4 hypothetical protein YP_002421703.1 3088652 D 440085 CDS YP_002421704.1 218530888 7115744 3089385..3091190 1 NC_011757.1 KEGG: mex:Mext_2710 malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; malto-oligosyltrehalose trehalohydrolase 3091190 7115744 Mchl_2937 Methylobacterium extorquens CM4 malto-oligosyltrehalose trehalohydrolase YP_002421704.1 3089385 D 440085 CDS YP_002421705.1 218530889 7115745 3091187..3096127 1 NC_011757.1 amylomaltase; acts to release glucose from maltodextrins; bifunctional 4-alpha-glucanotransferase/malto-oligosyltrehalose synthase 3096127 7115745 Mchl_2938 Methylobacterium extorquens CM4 bifunctional 4-alpha-glucanotransferase/malto-oligosyltrehalose synthase YP_002421705.1 3091187 D 440085 CDS YP_002421706.1 218530890 7115746 3096265..3099639 1 NC_011757.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: mex:Mext_2712 alpha amylase catalytic region; alpha amylase catalytic subunit 3099639 7115746 Mchl_2939 Methylobacterium extorquens CM4 alpha amylase catalytic subunit YP_002421706.1 3096265 D 440085 CDS YP_002421707.1 218530891 7115747 3099811..3103077 1 NC_011757.1 KEGG: mex:Mext_2713 trehalose synthase; TIGRFAM: trehalose synthase; trehalose synthase-fused maltokinase; PFAM: aminoglycoside phosphotransferase; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; trehalose synthase 3103077 7115747 Mchl_2940 Methylobacterium extorquens CM4 trehalose synthase YP_002421707.1 3099811 D 440085 CDS YP_002421708.1 218530892 7115748 3103140..3105494 1 NC_011757.1 KEGG: mex:Mext_2714 1,4-alpha-glucan branching enzyme; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; 1,4-alpha-glucan branching protein 3105494 7115748 Mchl_2941 Methylobacterium extorquens CM4 1,4-alpha-glucan branching protein YP_002421708.1 3103140 D 440085 CDS YP_002421709.1 218530893 7115749 complement(3105516..3105845) 1 NC_011757.1 PFAM: protein of unknown function UPF0060; KEGG: mex:Mext_2715 hypothetical protein; hypothetical protein 3105845 7115749 Mchl_2942 Methylobacterium extorquens CM4 hypothetical protein YP_002421709.1 3105516 R 440085 CDS YP_002421710.1 218530894 7115750 complement(3105940..3106212) 1 NC_011757.1 KEGG: mpo:Mpop_2838 hypothetical protein; hypothetical protein 3106212 7115750 Mchl_2943 Methylobacterium extorquens CM4 hypothetical protein YP_002421710.1 3105940 R 440085 CDS YP_002421711.1 218530895 7115751 3106317..3107432 1 NC_011757.1 KEGG: mex:Mext_2717 radical SAM domain-containing protein; radical SAM domain-containing protein 3107432 7115751 Mchl_2944 Methylobacterium extorquens CM4 radical SAM domain-containing protein YP_002421711.1 3106317 D 440085 CDS YP_002421712.1 218530896 7115752 complement(3107464..3108228) 1 NC_011757.1 PFAM: endonuclease III FCL domain protein; SMART: HhH-GPD family protein; KEGG: mex:Mext_2718 HhH-GPD family protein; endonuclease III FCL domain-containing protein 3108228 7115752 Mchl_2945 Methylobacterium extorquens CM4 endonuclease III FCL domain-containing protein YP_002421712.1 3107464 R 440085 CDS YP_002421713.1 218530897 7115753 complement(3108278..3109174) 1 NC_011757.1 PFAM: transcription activator effector binding; KEGG: mex:Mext_2719 transcription activator effector binding; transcription activator effector binding 3109174 7115753 Mchl_2946 Methylobacterium extorquens CM4 transcription activator effector binding YP_002421713.1 3108278 R 440085 CDS YP_002421714.1 218530898 7115754 3109248..3110138 1 NC_011757.1 PFAM: diaminopimelate epimerase; KEGG: mex:Mext_2720 diaminopimelate epimerase; diaminopimelate epimerase 3110138 7115754 Mchl_2947 Methylobacterium extorquens CM4 diaminopimelate epimerase YP_002421714.1 3109248 D 440085 CDS YP_002421715.1 218530899 7115755 3110135..3111367 1 NC_011757.1 KEGG: mex:Mext_2721 MiaB-like tRNA modifying enzyme; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: radical SAM protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein 3111367 7115755 Mchl_2948 Methylobacterium extorquens CM4 MiaB-like tRNA modifying protein YP_002421715.1 3110135 D 440085 CDS YP_002421716.1 218530900 7115756 complement(3111408..3112127) 1 NC_011757.1 PFAM: pseudouridine synthase; KEGG: mex:Mext_2722 pseudouridine synthase; pseudouridine synthase 3112127 7115756 Mchl_2949 Methylobacterium extorquens CM4 pseudouridine synthase YP_002421716.1 3111408 R 440085 CDS YP_002421717.1 218530901 7115757 3112201..3113667 1 NC_011757.1 KEGG: mex:Mext_2723 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; signal recognition particle-docking protein FtsY 3113667 7115757 Mchl_2950 Methylobacterium extorquens CM4 signal recognition particle-docking protein FtsY YP_002421717.1 3112201 D 440085 CDS YP_002421718.1 218530902 7118012 3113707..3114327 1 NC_011757.1 TIGRFAM: intracellular septation protein A; PFAM: Intracellular septation protein A; KEGG: mex:Mext_2724 intracellular septation protein A; intracellular septation protein A 3114327 7118012 Mchl_2951 Methylobacterium extorquens CM4 intracellular septation protein A YP_002421718.1 3113707 D 440085 CDS YP_002421719.1 218530903 7118147 complement(3114335..3115234) 1 NC_011757.1 PFAM: hydroxyneurosporene synthase; KEGG: mex:Mext_2725 hydroxyneurosporene synthase; hydroxyneurosporene synthase 3115234 7118147 Mchl_2952 Methylobacterium extorquens CM4 hydroxyneurosporene synthase YP_002421719.1 3114335 R 440085 CDS YP_002421720.1 218530904 7118148 complement(3115231..3116730) 1 NC_011757.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_2726 phytoene desaturase; phytoene desaturase 3116730 7118148 Mchl_2953 Methylobacterium extorquens CM4 phytoene desaturase YP_002421720.1 3115231 R 440085 CDS YP_002421721.1 218530905 7118149 3116836..3117702 1 NC_011757.1 PFAM: polyprenyl synthetase; KEGG: mex:Mext_2727 polyprenyl synthetase; polyprenyl synthetase 3117702 7118149 Mchl_2954 Methylobacterium extorquens CM4 polyprenyl synthetase YP_002421721.1 3116836 D 440085 CDS YP_002421722.1 218530906 7118150 3117712..3118869 1 NC_011757.1 PFAM: O-methyltransferase family 2; methyltransferase type 12; KEGG: mex:Mext_2728 O-methyltransferase family protein; O-methyltransferase family 2 3118869 7118150 Mchl_2955 Methylobacterium extorquens CM4 O-methyltransferase family 2 YP_002421722.1 3117712 D 440085 CDS YP_002421723.1 218530907 7118151 3118969..3119907 1 NC_011757.1 TIGRFAM: chlorophyll synthesis pathway, BchC; PFAM: alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_2729 chlorophyll synthesis pathway, BchC; chlorophyll synthesis pathway, BchC 3119907 7118151 Mchl_2956 Methylobacterium extorquens CM4 chlorophyll synthesis pathway, BchC YP_002421723.1 3118969 D 440085 CDS YP_002421724.1 218530908 7118152 3119904..3120908 1 NC_011757.1 KEGG: mex:Mext_2730 chlorophyllide reductase iron protein subunit X; TIGRFAM: chlorophyllide reductase iron protein subunit X; PFAM: NifH/frxC-family protein; chlorophyllide reductase iron protein subunit X 3120908 7118152 Mchl_2957 Methylobacterium extorquens CM4 chlorophyllide reductase iron protein subunit X YP_002421724.1 3119904 D 440085 CDS YP_002421725.1 218530909 7118153 3120912..3122438 1 NC_011757.1 TIGRFAM: chlorophyllide reductase subunit Y; PFAM: oxidoreductase/nitrogenase component 1; KEGG: mex:Mext_2731 chlorophyllide reductase subunit Y; chlorophyllide reductase subunit Y 3122438 7118153 Mchl_2958 Methylobacterium extorquens CM4 chlorophyllide reductase subunit Y YP_002421725.1 3120912 D 440085 CDS YP_002421726.1 218530910 7118154 3122438..3123904 1 NC_011757.1 TIGRFAM: chlorophyllide reductase subunit Z; PFAM: oxidoreductase/nitrogenase component 1; protein of unknown function DUF1197; KEGG: mex:Mext_2732 chlorophyllide reductase subunit Z; chlorophyllide reductase subunit Z 3123904 7118154 Mchl_2959 Methylobacterium extorquens CM4 chlorophyllide reductase subunit Z YP_002421726.1 3122438 D 440085 CDS YP_002421727.1 218530911 7118155 3123976..3124209 1 NC_011757.1 KEGG: mex:Mext_2733 hypothetical protein; hypothetical protein 3124209 7118155 Mchl_2960 Methylobacterium extorquens CM4 hypothetical protein YP_002421727.1 3123976 D 440085 CDS YP_002421728.1 218530912 7118156 3124379..3124609 1 NC_011757.1 PFAM: antenna complex alpha/subunit beta; KEGG: mex:Mext_2734 antenna complex alpha/subunit beta; antenna complex alpha/subunit beta 3124609 7118156 Mchl_2961 Methylobacterium extorquens CM4 antenna complex alpha/subunit beta YP_002421728.1 3124379 D 440085 CDS YP_002421729.1 218530913 7118157 3124621..3124809 1 NC_011757.1 PFAM: antenna complex alpha/subunit beta; KEGG: mex:Mext_2735 antenna complex alpha/subunit beta; antenna complex alpha/subunit beta 3124809 7118157 Mchl_2962 Methylobacterium extorquens CM4 antenna complex alpha/subunit beta YP_002421729.1 3124621 D 440085 CDS YP_002421730.1 218530914 7118158 3124885..3125709 1 NC_011757.1 TIGRFAM: photosynthetic reaction center L subunit; PFAM: photosynthetic reaction centre protein; KEGG: mex:Mext_2736 photosynthetic reaction center subunit L; photosynthetic reaction center subunit L 3125709 7118158 Mchl_2963 Methylobacterium extorquens CM4 photosynthetic reaction center subunit L YP_002421730.1 3124885 D 440085 CDS YP_002421731.1 218530915 7118159 3125832..3126809 1 NC_011757.1 TIGRFAM: photosynthetic reaction center, M subunit; PFAM: photosynthetic reaction centre protein; KEGG: mpo:Mpop_2859 photosynthetic reaction center, M subunit; photosynthetic reaction center subunit M 3126809 7118159 Mchl_2964 Methylobacterium extorquens CM4 photosynthetic reaction center subunit M YP_002421731.1 3125832 D 440085 CDS YP_002421732.1 218530916 7118161 3128314..3130062 1 NC_011757.1 KEGG: mex:Mext_2739 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; type I secretion system ATPase 3130062 7118161 Mchl_2966 Methylobacterium extorquens CM4 type I secretion system ATPase YP_002421732.1 3128314 D 440085 CDS YP_002421733.1 218530917 7118162 3130062..3131408 1 NC_011757.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD; KEGG: mex:Mext_2740 HlyD family type I secretion membrane fusion protein; HlyD family type I secretion membrane fusion protein 3131408 7118162 Mchl_2967 Methylobacterium extorquens CM4 HlyD family type I secretion membrane fusion protein YP_002421733.1 3130062 D 440085 CDS YP_002421734.1 218530918 7118163 3131561..3131686 1 NC_011757.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 3131686 rpmJ 7118163 rpmJ Methylobacterium extorquens CM4 50S ribosomal protein L36 YP_002421734.1 3131561 D 440085 CDS YP_002421735.1 218530919 7118164 3131764..3132372 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: mex:Mext_2742 hypotheticalprotein; hypothetical protein 3132372 7118164 Mchl_2969 Methylobacterium extorquens CM4 hypothetical protein YP_002421735.1 3131764 D 440085 CDS YP_002421736.1 218530920 7118165 3132383..3133378 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_2743 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 3133378 7118165 Mchl_2970 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002421736.1 3132383 D 440085 CDS YP_002421737.1 218530921 7118166 complement(3133430..3134866) 1 NC_011757.1 KEGG: mex:Mext_2744 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; pyruvate kinase 3134866 7118166 Mchl_2971 Methylobacterium extorquens CM4 pyruvate kinase YP_002421737.1 3133430 R 440085 CDS YP_002421738.1 218530922 7118167 3135234..3136091 1 NC_011757.1 KEGG: mex:Mext_2745 porin; porin 3136091 7118167 Mchl_2972 Methylobacterium extorquens CM4 porin YP_002421738.1 3135234 D 440085 CDS YP_002421739.1 218530923 7118168 complement(3136419..3136874) 1 NC_011757.1 PFAM: protein of unknown function DUF1036; KEGG: mex:Mext_2746 hypothetical protein; hypothetical protein 3136874 7118168 Mchl_2973 Methylobacterium extorquens CM4 hypothetical protein YP_002421739.1 3136419 R 440085 CDS YP_002421740.1 218530924 7118169 complement(3136927..3138240) 1 NC_011757.1 PFAM: MOFRL domain protein; KEGG: mex:Mext_2747 hydroxypyruvate reductase; hydroxypyruvate reductase 3138240 7118169 Mchl_2974 Methylobacterium extorquens CM4 hydroxypyruvate reductase YP_002421740.1 3136927 R 440085 CDS YP_002421741.1 218530925 7118170 3138468..3139241 1 NC_011757.1 PFAM: N-formylglutamate amidohydrolase; KEGG: mex:Mext_2748 N-formylglutamate amidohydrolase; N-formylglutamate amidohydrolase 3139241 7118170 Mchl_2975 Methylobacterium extorquens CM4 N-formylglutamate amidohydrolase YP_002421741.1 3138468 D 440085 CDS YP_002421742.1 218530926 7118171 3139312..3139620 1 NC_011757.1 PFAM: protein of unknown function DUF1244; KEGG: mex:Mext_2749 hypothetical protein; hypothetical protein 3139620 7118171 Mchl_2976 Methylobacterium extorquens CM4 hypothetical protein YP_002421742.1 3139312 D 440085 CDS YP_002421743.1 218530927 7118172 3139724..3139990 1 NC_011757.1 KEGG: mpo:Mpop_2872 hypothetical protein; hypothetical protein 3139990 7118172 Mchl_2977 Methylobacterium extorquens CM4 hypothetical protein YP_002421743.1 3139724 D 440085 CDS YP_002421744.1 218530928 7118173 complement(3140212..3141702) 1 NC_011757.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: mex:Mext_2751 hypothetical protein; hypothetical protein 3141702 7118173 Mchl_2978 Methylobacterium extorquens CM4 hypothetical protein YP_002421744.1 3140212 R 440085 CDS YP_002421745.1 218530929 7118174 complement(3141938..3143884) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2752 peptidoglycan binding domain-containing protein; ErfK/YbiS/YcfS/YnhG family protein 3143884 7118174 Mchl_2979 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421745.1 3141938 R 440085 CDS YP_002421746.1 218530930 7118175 complement(3144131..3145621) 1 NC_011757.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_2753 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 3145621 7118175 Mchl_2980 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002421746.1 3144131 R 440085 CDS YP_002421747.1 218530931 7118176 3145950..3147827 1 NC_011757.1 TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; oligopeptidase F; KEGG: mex:Mext_2754 PepF/M3 family oligoendopeptidase; oligoendopeptidase, pepF/M3 family 3147827 7118176 Mchl_2981 Methylobacterium extorquens CM4 oligoendopeptidase, pepF/M3 family YP_002421747.1 3145950 D 440085 CDS YP_002421748.1 218530932 7118177 3147896..3148120 1 NC_011757.1 TIGRFAM: addiction module antidote; PFAM: SpoVT/AbrB domain protein; KEGG: bra:BRADO1193 AbrB family transcriptional regulator; MazE family transcriptional regulator 3148120 7118177 Mchl_2982 Methylobacterium extorquens CM4 MazE family transcriptional regulator YP_002421748.1 3147896 D 440085 CDS YP_002421749.1 218530933 7118178 3148117..3148503 1 NC_011757.1 TIGRFAM: death-on-curing family protein; PFAM: filamentation induced by cAMP protein Fic; KEGG: mpo:Mpop_2879 death-on-curing family protein; death-on-curing family protein 3148503 7118178 Mchl_2983 Methylobacterium extorquens CM4 death-on-curing family protein YP_002421749.1 3148117 D 440085 CDS YP_002421750.1 218530934 7118179 3148596..3149966 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_2757 hypothetical protein; ABC transporter 3149966 7118179 Mchl_2984 Methylobacterium extorquens CM4 ABC transporter YP_002421750.1 3148596 D 440085 CDS YP_002421751.1 218530935 7118180 3150079..3150372 1 NC_011757.1 KEGG: mex:Mext_2758 hypothetical protein; hypothetical protein 3150372 7118180 Mchl_2985 Methylobacterium extorquens CM4 hypothetical protein YP_002421751.1 3150079 D 440085 CDS YP_002421752.1 218530936 7118181 3150484..3151623 1 NC_011757.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: mex:Mext_2759 NAD(P)(+) transhydrogenase (AB-specific); NAD(P)(+) transhydrogenase 3151623 7118181 Mchl_2986 Methylobacterium extorquens CM4 NAD(P)(+) transhydrogenase YP_002421752.1 3150484 D 440085 CDS YP_002421753.1 218530937 7118182 3151645..3152097 1 NC_011757.1 KEGG: mex:Mext_2760 PntAB, NAD(P) transhydrogenase, alpha2 subunit; PntAB, NAD(P) transhydrogenase, alpha2 subunit 3152097 7118182 Mchl_2987 Methylobacterium extorquens CM4 PntAB, NAD(P) transhydrogenase, alpha2 subunit YP_002421753.1 3151645 D 440085 CDS YP_002421754.1 218530938 7118183 3152102..3153502 1 NC_011757.1 PFAM: NAD(P) transhydrogenase subunit beta; KEGG: mex:Mext_2761 NAD(P)(+) transhydrogenase (AB-specific); NAD(P)(+) transhydrogenase 3153502 7118183 Mchl_2988 Methylobacterium extorquens CM4 NAD(P)(+) transhydrogenase YP_002421754.1 3152102 D 440085 CDS YP_002421755.1 218530939 7118184 3153597..3155432 1 NC_011757.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mex:Mext_2762 single-stranded-DNA-specific exonuclease RecJ; single-stranded-DNA-specific exonuclease RecJ 3155432 7118184 Mchl_2989 Methylobacterium extorquens CM4 single-stranded-DNA-specific exonuclease RecJ YP_002421755.1 3153597 D 440085 CDS YP_002421756.1 218530940 7118186 3155890..3156624 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_2763 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 3156624 7118186 Mchl_2990 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002421756.1 3155890 D 440085 CDS YP_002421757.1 218530941 7118187 3156676..3157380 1 NC_011757.1 PFAM: HWE histidine kinase; KEGG: mex:Mext_2764 HWE histidine kinase; signal transduction histidine kinase 3157380 7118187 Mchl_2991 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002421757.1 3156676 D 440085 CDS YP_002421758.1 218530942 7118188 3157584..3159569 1 NC_011757.1 PFAM: surface antigen (D15); KEGG: mex:Mext_2765 surface antigen (D15); surface antigen (D15) 3159569 7118188 Mchl_2992 Methylobacterium extorquens CM4 surface antigen (D15) YP_002421758.1 3157584 D 440085 CDS YP_002421759.1 218530943 7118189 3159570..3163961 1 NC_011757.1 PFAM: protein of unknown function DUF490; KEGG: mex:Mext_2766 hypothetical protein; hypothetical protein 3163961 7118189 Mchl_2993 Methylobacterium extorquens CM4 hypothetical protein YP_002421759.1 3159570 D 440085 CDS YP_002421760.1 218530944 7118190 3164431..3164691 1 NC_011757.1 KEGG: mpo:Mpop_2890 hypothetical protein; hypothetical protein 3164691 7118190 Mchl_2994 Methylobacterium extorquens CM4 hypothetical protein YP_002421760.1 3164431 D 440085 CDS YP_002421761.1 218530945 7118191 3164884..3165153 1 NC_011757.1 KEGG: mex:Mext_2768 hypothetical protein; hypothetical protein 3165153 7118191 Mchl_2995 Methylobacterium extorquens CM4 hypothetical protein YP_002421761.1 3164884 D 440085 CDS YP_002421762.1 218530946 7118192 complement(3165255..3165743) 1 NC_011757.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 3165743 7118192 Mchl_2996 Methylobacterium extorquens CM4 cyanate hydratase YP_002421762.1 3165255 R 440085 CDS YP_002421763.1 218530947 7118193 3166032..3167921 1 NC_011757.1 KEGG: mex:Mext_2770 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; ATPase AAA; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; ATPase AAA; PAS/PAC sensor protein 3167921 7118193 Mchl_2997 Methylobacterium extorquens CM4 PAS/PAC sensor protein YP_002421763.1 3166032 D 440085 CDS YP_002421764.1 218530948 7118194 3168006..3169610 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_2771 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 3169610 7118194 Mchl_2998 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002421764.1 3168006 D 440085 CDS YP_002421765.1 218530949 7118195 complement(3169635..3170693) 1 NC_011757.1 PFAM: Di-haem cytochrome C peroxidase; KEGG: mex:Mext_2772 cytochrome-c peroxidase; cytochrome-c peroxidase 3170693 7118195 Mchl_2999 Methylobacterium extorquens CM4 cytochrome-c peroxidase YP_002421765.1 3169635 R 440085 CDS YP_002421766.1 218530950 7118196 complement(3170863..3171234) 1 NC_011757.1 KEGG: mex:Mext_2773 hypothetical protein; hypothetical protein 3171234 7118196 Mchl_3000 Methylobacterium extorquens CM4 hypothetical protein YP_002421766.1 3170863 R 440085 CDS YP_002421767.1 218530951 7118197 3171418..3174282 1 NC_011757.1 KEGG: mex:Mext_2774 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 3174282 7118197 Mchl_3001 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_002421767.1 3171418 D 440085 CDS YP_002421768.1 218530952 7118198 3174517..3175374 1 NC_011757.1 PFAM: manganese containing catalase; KEGG: mex:Mext_2775 catalase; catalase 3175374 7118198 Mchl_3002 Methylobacterium extorquens CM4 catalase YP_002421768.1 3174517 D 440085 CDS YP_002421769.1 218530953 7118199 3175453..3175962 1 NC_011757.1 PFAM: protein of unknown function DUF892; KEGG: mex:Mext_2776 hypothetical protein; hypothetical protein 3175962 7118199 Mchl_3003 Methylobacterium extorquens CM4 hypothetical protein YP_002421769.1 3175453 D 440085 CDS YP_002421770.1 218530954 7118200 complement(3176152..3176823) 1 NC_011757.1 KEGG: mex:Mext_2777 hypothetical protein; hypothetical protein 3176823 7118200 Mchl_3004 Methylobacterium extorquens CM4 hypothetical protein YP_002421770.1 3176152 R 440085 CDS YP_002421771.1 218530955 7118201 3176912..3177163 1 NC_011757.1 KEGG: mex:Mext_2778 hypothetical protein; hypothetical protein 3177163 7118201 Mchl_3005 Methylobacterium extorquens CM4 hypothetical protein YP_002421771.1 3176912 D 440085 CDS YP_002421772.1 218530956 7118203 3177552..3179396 1 NC_011757.1 PFAM: CBS domain containing protein; chloride channel core; KEGG: mex:Mext_2779 chloride channel core; chloride channel core 3179396 7118203 Mchl_3006 Methylobacterium extorquens CM4 chloride channel core YP_002421772.1 3177552 D 440085 CDS YP_002421773.1 218530957 7118204 3179425..3179913 1 NC_011757.1 KEGG: mex:Mext_2780 hypothetical protein; hypothetical protein 3179913 7118204 Mchl_3007 Methylobacterium extorquens CM4 hypothetical protein YP_002421773.1 3179425 D 440085 CDS YP_002421774.1 218530958 7118205 3179924..3180772 1 NC_011757.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 3180772 7118205 Mchl_3008 Methylobacterium extorquens CM4 2-dehydro-3-deoxyphosphooctonate aldolase YP_002421774.1 3179924 D 440085 CDS YP_002421775.1 218530959 7118206 3180949..3181260 1 NC_011757.1 KEGG: mex:Mext_2782 transmembrane protein; transmembrane protein 3181260 7118206 Mchl_3009 Methylobacterium extorquens CM4 transmembrane protein YP_002421775.1 3180949 D 440085 CDS YP_002421776.1 218530960 7118207 3181325..3181573 1 NC_011757.1 hypothetical protein 3181573 7118207 Mchl_3010 Methylobacterium extorquens CM4 hypothetical protein YP_002421776.1 3181325 D 440085 CDS YP_002421777.1 218530961 7118208 complement(3181592..3182053) 1 NC_011757.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3182053 7118208 Mchl_3011 Methylobacterium extorquens CM4 7-cyano-7-deazaguanine reductase YP_002421777.1 3181592 R 440085 CDS YP_002421778.1 218530962 7118209 3182345..3183634 1 NC_011757.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3183634 eno 7118209 eno Methylobacterium extorquens CM4 phosphopyruvate hydratase YP_002421778.1 3182345 D 440085 CDS YP_002421779.1 218530963 7118210 3183770..3184081 1 NC_011757.1 PFAM: septum formation initiator; KEGG: mex:Mext_2785 septum formation initiator; septum formation initiator 3184081 7118210 Mchl_3013 Methylobacterium extorquens CM4 septum formation initiator YP_002421779.1 3183770 D 440085 CDS YP_002421780.1 218530964 7118211 3184257..3185306 1 NC_011757.1 KEGG: mex:Mext_2786 pyruvate dehydrogenase (acetyl-transferring) E1 component, subunit alpha; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, subunit alpha; PFAM: dehydrogenase E1 component; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha 3185306 7118211 Mchl_3014 Methylobacterium extorquens CM4 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha YP_002421780.1 3184257 D 440085 CDS YP_002421781.1 218530965 7118212 3185412..3186860 1 NC_011757.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 3186860 7118212 Mchl_3015 Methylobacterium extorquens CM4 pyruvate dehydrogenase subunit beta YP_002421781.1 3185412 D 440085 CDS YP_002421782.1 218530966 7118213 3186871..3187149 1 NC_011757.1 KEGG: mex:Mext_2788 hypothetical protein; hypothetical protein 3187149 7118213 Mchl_3016 Methylobacterium extorquens CM4 hypothetical protein YP_002421782.1 3186871 D 440085 CDS YP_002421783.1 218530967 7118214 3187183..3188595 1 NC_011757.1 KEGG: mex:Mext_2789 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 3188595 7118214 Mchl_3017 Methylobacterium extorquens CM4 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase YP_002421783.1 3187183 D 440085 CDS YP_002421784.1 218530968 7118215 3188758..3190197 1 NC_011757.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 3190197 7118215 Mchl_3018 Methylobacterium extorquens CM4 dihydrolipoamide dehydrogenase YP_002421784.1 3188758 D 440085 CDS YP_002421785.1 218530969 7118216 3190408..3190611 1 NC_011757.1 KEGG: mex:Mext_2791 hypothetical protein; hypothetical protein 3190611 7118216 Mchl_3019 Methylobacterium extorquens CM4 hypothetical protein YP_002421785.1 3190408 D 440085 CDS YP_002421786.1 218530970 7118217 complement(3190708..3191220) 1 NC_011757.1 KEGG: mex:Mext_2792 hypothetical protein; hypothetical protein 3191220 7118217 Mchl_3020 Methylobacterium extorquens CM4 hypothetical protein YP_002421786.1 3190708 R 440085 CDS YP_002421787.1 218530971 7118218 3191506..3192009 1 NC_011757.1 KEGG: mex:Mext_2793 endo-1,4-beta-glucanase; endo-1,4-beta-glucanase 3192009 7118218 Mchl_3021 Methylobacterium extorquens CM4 endo-1,4-beta-glucanase YP_002421787.1 3191506 D 440085 CDS YP_002421788.1 218530972 7118219 3192127..3192387 1 NC_011757.1 KEGG: mex:Mext_2794 hypothetical protein; hypothetical protein 3192387 7118219 Mchl_3022 Methylobacterium extorquens CM4 hypothetical protein YP_002421788.1 3192127 D 440085 CDS YP_002421789.1 218530973 7118220 3192466..3193110 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2795 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3193110 7118220 Mchl_3023 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421789.1 3192466 D 440085 CDS YP_002421790.1 218530974 7118221 complement(3193280..3194626) 1 NC_011757.1 KEGG: mex:Mext_2796 L-sorbosone dehydrogenase; L-sorbosone dehydrogenase 3194626 7118221 Mchl_3024 Methylobacterium extorquens CM4 L-sorbosone dehydrogenase YP_002421790.1 3193280 R 440085 CDS YP_002421791.1 218530975 7118222 complement(3194648..3194860) 1 NC_011757.1 KEGG: mex:Mext_2797 hypothetical protein; hypothetical protein 3194860 7118222 Mchl_3025 Methylobacterium extorquens CM4 hypothetical protein YP_002421791.1 3194648 R 440085 CDS YP_002421792.1 218530976 7118223 3195060..3195797 1 NC_011757.1 PFAM: cell wall hydrolase SleB; KEGG: mex:Mext_2798 cell wall hydrolase SleB; cell wall hydrolase SleB 3195797 7118223 Mchl_3026 Methylobacterium extorquens CM4 cell wall hydrolase SleB YP_002421792.1 3195060 D 440085 CDS YP_002421793.1 218530977 7118224 3195931..3196950 1 NC_011757.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 3196950 7118224 Mchl_3027 Methylobacterium extorquens CM4 lipoyl synthase YP_002421793.1 3195931 D 440085 CDS YP_002421794.1 218530978 7118225 3196957..3197415 1 NC_011757.1 PFAM: cyclase/dehydrase; KEGG: mex:Mext_2800 cyclase/dehydrase; cyclase/dehydrase 3197415 7118225 Mchl_3028 Methylobacterium extorquens CM4 cyclase/dehydrase YP_002421794.1 3196957 D 440085 CDS YP_002421795.1 218530979 7118226 complement(3197498..3197923) 1 NC_011757.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: mex:Mext_2801 AsnC/Lrp family regulatory protein; AsnC family transcriptional regulator 3197923 7118226 Mchl_3029 Methylobacterium extorquens CM4 AsnC family transcriptional regulator YP_002421795.1 3197498 R 440085 CDS YP_002421796.1 218530980 7118227 3198081..3199085 1 NC_011757.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 3199085 7118227 Mchl_3030 Methylobacterium extorquens CM4 ornithine cyclodeaminase YP_002421796.1 3198081 D 440085 CDS YP_002421797.1 218530981 7118228 3199397..3200437 1 NC_011757.1 PFAM: chalcone and stilbene synthase domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: mex:Mext_2803 beta-ketoacyl-acyl-carrier-protein synthase I; beta-ketoacyl-acyl-carrier-protein synthase I 3200437 7118228 Mchl_3031 Methylobacterium extorquens CM4 beta-ketoacyl-acyl-carrier-protein synthase I YP_002421797.1 3199397 D 440085 CDS YP_002421798.1 218530982 7118310 3200457..3200690 1 NC_011757.1 KEGG: mex:Mext_2804 hypothetical protein; hypothetical protein 3200690 7118310 Mchl_3032 Methylobacterium extorquens CM4 hypothetical protein YP_002421798.1 3200457 D 440085 CDS YP_002421799.1 218530983 7118311 3200691..3201737 1 NC_011757.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: mex:Mext_2805 beta-ketoacyl-acyl-carrier-protein synthase I; beta-ketoacyl-acyl-carrier-protein synthase I 3201737 7118311 Mchl_3033 Methylobacterium extorquens CM4 beta-ketoacyl-acyl-carrier-protein synthase I YP_002421799.1 3200691 D 440085 CDS YP_002421800.1 218530984 7118312 3201734..3202495 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_2806 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3202495 7118312 Mchl_3034 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002421800.1 3201734 D 440085 CDS YP_002421801.1 218530985 7118313 complement(3202424..3203572) 1 NC_011757.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mex:Mext_2807 Rieske (2Fe-2S) domain-containing protein; Rieske (2Fe-2S) domain-containing protein 3203572 7118313 Mchl_3035 Methylobacterium extorquens CM4 Rieske (2Fe-2S) domain-containing protein YP_002421801.1 3202424 R 440085 CDS YP_002421802.1 218530986 7118314 3203979..3204629 1 NC_011757.1 KEGG: mex:Mext_2808 hexapeptide transferase family protein; hexapeptide transferase family protein 3204629 7118314 Mchl_3036 Methylobacterium extorquens CM4 hexapeptide transferase family protein YP_002421802.1 3203979 D 440085 CDS YP_002421803.1 218530987 7118315 complement(3204820..3206973) 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_4; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: mex:Mext_2809 hypotheticalprotein; hypothetical protein 3206973 7118315 Mchl_3037 Methylobacterium extorquens CM4 hypothetical protein YP_002421803.1 3204820 R 440085 CDS YP_002421804.1 218530988 7118316 complement(3207160..3207498) 1 NC_011757.1 KEGG: mex:Mext_2810 hypothetical protein; hypothetical protein 3207498 7118316 Mchl_3038 Methylobacterium extorquens CM4 hypothetical protein YP_002421804.1 3207160 R 440085 CDS YP_002421805.1 218530989 7118317 complement(3207495..3209282) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_2811 ABC transporter; ABC transporter 3209282 7118317 Mchl_3039 Methylobacterium extorquens CM4 ABC transporter YP_002421805.1 3207495 R 440085 CDS YP_002421806.1 218530990 7118318 3210173..3210670 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_2813 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 3210670 7118318 Mchl_3040 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002421806.1 3210173 D 440085 CDS YP_002421807.1 218530991 7118319 3210667..3211716 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: mex:Mext_2814 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 3211716 7118319 Mchl_3041 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002421807.1 3210667 D 440085 CDS YP_002421808.1 218530992 7118320 3211709..3213952 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_2815 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 3213952 7118320 Mchl_3042 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002421808.1 3211709 D 440085 CDS YP_002421809.1 218530993 7118321 complement(3214040..3214567) 1 NC_011757.1 PFAM: damage inducible protein CinA; KEGG: mex:Mext_2816 CinA domain-containing protein; damage inducible protein CinA 3214567 7118321 Mchl_3043 Methylobacterium extorquens CM4 damage inducible protein CinA YP_002421809.1 3214040 R 440085 CDS YP_002421810.1 218530994 7118322 complement(3214564..3215898) 1 NC_011757.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MECDP-synthase; KEGG: mex:Mext_2817 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3215898 7118322 Mchl_3044 Methylobacterium extorquens CM4 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002421810.1 3214564 R 440085 CDS YP_002421811.1 218530995 7118323 3216026..3217054 1 NC_011757.1 TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; KEGG: mex:Mext_2818 NifR3 family TIM-barrel protein; hypothetical protein 3217054 7118323 Mchl_3045 Methylobacterium extorquens CM4 hypothetical protein YP_002421811.1 3216026 D 440085 CDS YP_002421812.1 218530996 7118324 3217054..3218187 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: mex:Mext_2819 PAS sensor protein; signal transduction histidine kinase, nitrogen specific, NtrB 3218187 7118324 Mchl_3046 Methylobacterium extorquens CM4 signal transduction histidine kinase, nitrogen specific, NtrB YP_002421812.1 3217054 D 440085 CDS YP_002421813.1 218530997 7118325 3218198..3219670 1 NC_011757.1 KEGG: mex:Mext_2820 nitrogen regulation protein NR(I); TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; Fis family transcriptional regulator 3219670 7118325 Mchl_3047 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002421813.1 3218198 D 440085 CDS YP_002421814.1 218530998 7118326 3219798..3221435 1 NC_011757.1 PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: mex:Mext_2821 helicase domain-containing protein; helicase 3221435 7118326 Mchl_3048 Methylobacterium extorquens CM4 helicase YP_002421814.1 3219798 D 440085 CDS YP_002421815.1 218530999 7118327 3221499..3223898 1 NC_011757.1 KEGG: mex:Mext_2822 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor signal transduction histidine kinase 3223898 7118327 Mchl_3049 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002421815.1 3221499 D 440085 CDS YP_002421816.1 218531000 7118328 3223895..3225265 1 NC_011757.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: mex:Mext_2823 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 3225265 7118328 Mchl_3050 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002421816.1 3223895 D 440085 CDS YP_002421817.1 218531001 7118329 3225574..3225828 1 NC_011757.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: mpo:Mpop_2942 RNA chaperone Hfq; RNA chaperone Hfq 3225828 7118329 Mchl_3051 Methylobacterium extorquens CM4 RNA chaperone Hfq YP_002421817.1 3225574 D 440085 CDS YP_002421818.1 218531002 7118330 3225926..3227341 1 NC_011757.1 TIGRFAM: GTP-binding proten HflX; PFAM: GTP-binding protein HSR1-related; KEGG: mex:Mext_2825 GTP-binding protein HflX; GTP-binding proten HflX 3227341 7118330 Mchl_3052 Methylobacterium extorquens CM4 GTP-binding proten HflX YP_002421818.1 3225926 D 440085 CDS YP_002421819.1 218531003 7118331 complement(3227488..3229056) 1 NC_011757.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: mex:Mext_2826 sulfate transporter; sulfate transporter 3229056 7118331 Mchl_3053 Methylobacterium extorquens CM4 sulfate transporter YP_002421819.1 3227488 R 440085 CDS YP_002421820.1 218531004 7118332 complement(3229066..3229842) 1 NC_011757.1 PFAM: carbonic anhydrase; KEGG: mex:Mext_2827 carbonate dehydratase; carbonate dehydratase 3229842 7118332 Mchl_3054 Methylobacterium extorquens CM4 carbonate dehydratase YP_002421820.1 3229066 R 440085 CDS YP_002421821.1 218531005 7118333 complement(3230118..3230429) 1 NC_011757.1 KEGG: mex:Mext_2828 hypothetical protein; hypothetical protein 3230429 7118333 Mchl_3055 Methylobacterium extorquens CM4 hypothetical protein YP_002421821.1 3230118 R 440085 CDS YP_002421822.1 218531006 7118334 complement(3231270..3231656) 1 NC_011757.1 PFAM: protein of unknown function DUF305; KEGG: mex:Mext_2829 hypothetical protein; hypothetical protein 3231656 7118334 Mchl_3056 Methylobacterium extorquens CM4 hypothetical protein YP_002421822.1 3231270 R 440085 CDS YP_002421823.1 218531007 7118335 complement(3231686..3232063) 1 NC_011757.1 KEGG: mex:Mext_2830 hypothetical protein; hypothetical protein 3232063 7118335 Mchl_3057 Methylobacterium extorquens CM4 hypothetical protein YP_002421823.1 3231686 R 440085 CDS YP_002421824.1 218531008 7118336 complement(3232090..3235290) 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_2831 acriflavin resistance protein; acriflavin resistance protein 3235290 7118336 Mchl_3058 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002421824.1 3232090 R 440085 CDS YP_002421825.1 218531009 7118337 complement(3235380..3237107) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: mex:Mext_2832 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 3237107 7118337 Mchl_3059 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002421825.1 3235380 R 440085 CDS YP_002421826.1 218531010 7118338 3238203..3238691 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_2834 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 3238691 7118338 Mchl_3060 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002421826.1 3238203 D 440085 CDS YP_002421827.1 218531011 7118339 3238830..3239330 1 NC_011757.1 PFAM: CheW domain protein; KEGG: mex:Mext_2835 CheW domain-containing protein; CheW protein 3239330 7118339 Mchl_3061 Methylobacterium extorquens CM4 CheW protein YP_002421827.1 3238830 D 440085 CDS YP_002421828.1 218531012 7118340 3239342..3240799 1 NC_011757.1 PFAM: MCP methyltransferase CheR-type; KEGG: mex:Mext_2836 protein-glutamate O-methyltransferase; CheR-typeMCP methyltransferase 3240799 7118340 Mchl_3062 Methylobacterium extorquens CM4 CheR-typeMCP methyltransferase YP_002421828.1 3239342 D 440085 CDS YP_002421829.1 218531013 7118341 3240796..3241353 1 NC_011757.1 PFAM: CheW domain protein; KEGG: mex:Mext_2837 CheW domain-containing protein; CheW protein 3241353 7118341 Mchl_3063 Methylobacterium extorquens CM4 CheW protein YP_002421829.1 3240796 D 440085 CDS YP_002421830.1 218531014 7118342 3241434..3243182 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_2838 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3243182 7118342 Mchl_3064 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002421830.1 3241434 D 440085 CDS YP_002421831.1 218531015 7118343 3243207..3245453 1 NC_011757.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: mex:Mext_2839 response regulator receiver; CheA signal transduction histidine kinase 3245453 7118343 Mchl_3065 Methylobacterium extorquens CM4 CheA signal transduction histidine kinase YP_002421831.1 3243207 D 440085 CDS YP_002421832.1 218531016 7118344 3245450..3246535 1 NC_011757.1 PFAM: CheB methylesterase; response regulator receiver; KEGG: mex:Mext_2840 protein-glutamate methylesterase; response regulator receiver modulated CheB methylesterase 3246535 7118344 Mchl_3066 Methylobacterium extorquens CM4 response regulator receiver modulated CheB methylesterase YP_002421832.1 3245450 D 440085 CDS YP_002421833.1 218531017 7118345 3246532..3248265 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_2841 ATPase domain-containing protein; response regulator receiver sensor signal transduction histidine kinase 3248265 7118345 Mchl_3067 Methylobacterium extorquens CM4 response regulator receiver sensor signal transduction histidine kinase YP_002421833.1 3246532 D 440085 CDS YP_002421834.1 218531018 7118346 3248262..3250130 1 NC_011757.1 KEGG: mex:Mext_2842 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 3250130 7118346 Mchl_3068 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002421834.1 3248262 D 440085 CDS YP_002421835.1 218531019 7118347 3250285..3250458 1 NC_011757.1 PFAM: metallothionein family 14; KEGG: mex:Mext_2843 metallothionein family protein; metallothionein family 14 3250458 7118347 Mchl_3069 Methylobacterium extorquens CM4 metallothionein family 14 YP_002421835.1 3250285 D 440085 CDS YP_002421836.1 218531020 7118348 complement(3250486..3251802) 1 NC_011757.1 PFAM: hypothetical protein; cytochrome C class I; KEGG: mex:Mext_2844 WD-40 repeat-containing protein; hypothetical protein 3251802 7118348 Mchl_3070 Methylobacterium extorquens CM4 hypothetical protein YP_002421836.1 3250486 R 440085 CDS YP_002421837.1 218531021 7118349 3252027..3253112 1 NC_011757.1 PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mex:Mext_2845 molybdopterin binding domain-containing protein; molybdopterin binding domain 3253112 7118349 Mchl_3071 Methylobacterium extorquens CM4 molybdopterin binding domain YP_002421837.1 3252027 D 440085 CDS YP_002421838.1 218531022 7118350 3253109..3255079 1 NC_011757.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mex:Mext_2846 molybdenum cofactor synthesis domain-containing protein; molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein 3255079 7118350 Mchl_3072 Methylobacterium extorquens CM4 molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein YP_002421838.1 3253109 D 440085 CDS YP_002421839.1 218531023 7118351 3255076..3255612 1 NC_011757.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: mex:Mext_2847 molybdopterin-guanine dinucleotide biosynthesis protein B; molybdopterin-guanine dinucleotide biosynthesis protein B 3255612 7118351 Mchl_3073 Methylobacterium extorquens CM4 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002421839.1 3255076 D 440085 CDS YP_002421840.1 218531024 7118352 3255616..3256866 1 NC_011757.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mex:Mext_2848 molybdenum cofactor synthesis domain-containing protein; molybdenum cofactor synthesis protein 3256866 7118352 Mchl_3074 Methylobacterium extorquens CM4 molybdenum cofactor synthesis protein YP_002421840.1 3255616 D 440085 CDS YP_002421841.1 218531025 7118353 complement(3256921..3257961) 1 NC_011757.1 PFAM: regulatory protein LysR; KEGG: mex:Mext_2849 regulatory protein LysR; transcriptional regulator of molybdate metabolism, LysR family 3257961 7118353 Mchl_3075 Methylobacterium extorquens CM4 transcriptional regulator of molybdate metabolism, LysR family YP_002421841.1 3256921 R 440085 CDS YP_002421842.1 218531026 7118354 3258087..3258782 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_2850 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 3258782 7118354 Mchl_3076 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002421842.1 3258087 D 440085 CDS YP_002421843.1 218531027 7118355 3258779..3259495 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_2851 ABC transporter; ABC transporter 3259495 7118355 Mchl_3077 Methylobacterium extorquens CM4 ABC transporter YP_002421843.1 3258779 D 440085 CDS YP_002421844.1 218531028 7118356 3259468..3260295 1 NC_011757.1 PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_2852 extracellular solute-binding protein; family 1 extracellular solute-binding protein 3260295 7118356 Mchl_3078 Methylobacterium extorquens CM4 family 1 extracellular solute-binding protein YP_002421844.1 3259468 D 440085 CDS YP_002421845.1 218531029 7118357 complement(3260461..3260697) 1 NC_011757.1 KEGG: mex:Mext_2853 hypothetical protein; hypothetical protein 3260697 7118357 Mchl_3079 Methylobacterium extorquens CM4 hypothetical protein YP_002421845.1 3260461 R 440085 CDS YP_002421846.1 218531030 7118358 complement(3260741..3261385) 1 NC_011757.1 PFAM: PRC-barrel domain protein; KEGG: mex:Mext_2854 PRC-barrel domain-containing protein; PRC-barrel domain-containing protein 3261385 7118358 Mchl_3080 Methylobacterium extorquens CM4 PRC-barrel domain-containing protein YP_002421846.1 3260741 R 440085 CDS YP_002421847.1 218531031 7118359 complement(3261454..3263130) 1 NC_011757.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 3263130 mdoG 7118359 mdoG Methylobacterium extorquens CM4 glucan biosynthesis protein G YP_002421847.1 3261454 R 440085 CDS YP_002421848.1 218531032 7118360 3263165..3265096 1 NC_011757.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 3265096 7118360 Mchl_3082 Methylobacterium extorquens CM4 glucosyltransferase MdoH YP_002421848.1 3263165 D 440085 CDS YP_002421849.1 218531033 7118361 complement(3265189..3265656) 1 NC_011757.1 KEGG: mex:Mext_2857 hypothetical protein; hypothetical protein 3265656 7118361 Mchl_3083 Methylobacterium extorquens CM4 hypothetical protein YP_002421849.1 3265189 R 440085 CDS YP_002421850.1 218531034 7118362 complement(3265746..3266963) 1 NC_011757.1 PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mex:Mext_2858 cystathionine gamma-synthase; cystathionine gamma-synthase 3266963 7118362 Mchl_3084 Methylobacterium extorquens CM4 cystathionine gamma-synthase YP_002421850.1 3265746 R 440085 CDS YP_002421851.1 218531035 7118363 3267061..3267576 1 NC_011757.1 PFAM: TspO/MBR family protein; KEGG: mex:Mext_2859 TspO/MBR family protein; TspO and MBR-like protein 3267576 7118363 Mchl_3085 Methylobacterium extorquens CM4 TspO and MBR-like protein YP_002421851.1 3267061 D 440085 CDS YP_002421852.1 218531036 7118364 complement(3267692..3268057) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_2860 response regulator receiver; response regulator receiver protein 3268057 7118364 Mchl_3086 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421852.1 3267692 R 440085 CDS YP_002421853.1 218531037 7118365 complement(3268221..3268790) 1 NC_011757.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 3268790 7118365 Mchl_3087 Methylobacterium extorquens CM4 hypoxanthine phosphoribosyltransferase YP_002421853.1 3268221 R 440085 CDS YP_002421854.1 218531038 7118366 complement(3268979..3269734) 1 NC_011757.1 TIGRFAM: MJ0042 family finger-like protein; KEGG: mex:Mext_2862 zinc finger-domain-containing protein; MJ0042 family finger-like protein 3269734 7118366 Mchl_3088 Methylobacterium extorquens CM4 MJ0042 family finger-like protein YP_002421854.1 3268979 R 440085 CDS YP_002421855.1 218531039 7118367 3269892..3270605 1 NC_011757.1 KEGG: mex:Mext_2863 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: ATPase AAA; cell division ATP-binding protein FtsE 3270605 7118367 Mchl_3089 Methylobacterium extorquens CM4 cell division ATP-binding protein FtsE YP_002421855.1 3269892 D 440085 CDS YP_002421856.1 218531040 7118368 3270602..3271582 1 NC_011757.1 KEGG: mex:Mext_2864 hypothetical protein; hypothetical protein 3271582 7118368 Mchl_3090 Methylobacterium extorquens CM4 hypothetical protein YP_002421856.1 3270602 D 440085 CDS YP_002421857.1 218531041 7118369 3271824..3272528 1 NC_011757.1 PFAM: protein of unknown function DUF218; KEGG: mex:Mext_2865 hypothetical protein; hypothetical protein 3272528 7118369 Mchl_3091 Methylobacterium extorquens CM4 hypothetical protein YP_002421857.1 3271824 D 440085 CDS YP_002421858.1 218531042 7118370 complement(3272622..3272996) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_2866 response regulator receiver; response regulator receiver protein 3272996 7118370 Mchl_3092 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421858.1 3272622 R 440085 CDS YP_002421859.1 218531043 7118371 3273268..3274401 1 NC_011757.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 3274401 7118371 Mchl_3093 Methylobacterium extorquens CM4 gamma-glutamyl kinase YP_002421859.1 3273268 D 440085 CDS YP_002421860.1 218531044 7118372 3274541..3275839 1 NC_011757.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 3275839 proA 7118372 proA Methylobacterium extorquens CM4 gamma-glutamyl phosphate reductase YP_002421860.1 3274541 D 440085 CDS YP_002421861.1 218531045 7118373 3275895..3276452 1 NC_011757.1 TIGRFAM: cytidyltransferase-related domain protein; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; KEGG: mex:Mext_2869 nicotinate (nicotinamide) nucleotide adenylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 3276452 7118373 Mchl_3095 Methylobacterium extorquens CM4 nicotinate (nicotinamide) nucleotide adenylyltransferase YP_002421861.1 3275895 D 440085 CDS YP_002421862.1 218531046 7118374 3276895..3277197 1 NC_011757.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: mex:Mext_2870 iojap-like protein; iojap-like protein 3277197 7118374 Mchl_3096 Methylobacterium extorquens CM4 iojap-like protein YP_002421862.1 3276895 D 440085 CDS YP_002421863.1 218531047 7118375 complement(3277206..3277901) 1 NC_011757.1 KEGG: mex:Mext_2871 hypothetical protein; hypothetical protein 3277901 7118375 Mchl_3097 Methylobacterium extorquens CM4 hypothetical protein YP_002421863.1 3277206 R 440085 CDS YP_002421864.1 218531048 7118376 complement(3277955..3278515) 1 NC_011757.1 KEGG: mex:Mext_2872 transcriptional regulator; transcriptional regulator 3278515 7118376 Mchl_3098 Methylobacterium extorquens CM4 transcriptional regulator YP_002421864.1 3277955 R 440085 CDS YP_002421865.1 218531049 7118377 complement(3278603..3279643) 1 NC_011757.1 PFAM: aldose 1-epimerase; KEGG: mex:Mext_2873 aldose 1-epimerase; aldose 1-epimerase 3279643 7118377 Mchl_3099 Methylobacterium extorquens CM4 aldose 1-epimerase YP_002421865.1 3278603 R 440085 CDS YP_002421866.1 218531050 7118378 complement(3279740..3281533) 1 NC_011757.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: ATPase AAA; KEGG: mex:Mext_2874 ABC transporter related; ABC transporter 3281533 7118378 Mchl_3100 Methylobacterium extorquens CM4 ABC transporter YP_002421866.1 3279740 R 440085 CDS YP_002421867.1 218531051 7118379 3281806..3282735 1 NC_011757.1 PFAM: periplasmic solute binding protein; KEGG: mex:Mext_2875 periplasmic solute binding protein; periplasmic solute binding protein 3282735 7118379 Mchl_3101 Methylobacterium extorquens CM4 periplasmic solute binding protein YP_002421867.1 3281806 D 440085 CDS YP_002421868.1 218531052 7118380 complement(3282858..3283118) 1 NC_011757.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: mpo:Mpop_2999 molybdopterin converting factor, subunit 1; molybdopterin converting factor subunit 1 3283118 7118380 Mchl_3102 Methylobacterium extorquens CM4 molybdopterin converting factor subunit 1 YP_002421868.1 3282858 R 440085 CDS YP_002421869.1 218531053 7118381 complement(3283164..3283763) 1 NC_011757.1 TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: mex:Mext_2877 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase 3283763 7118381 Mchl_3103 Methylobacterium extorquens CM4 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase YP_002421869.1 3283164 R 440085 CDS YP_002421870.1 218531054 7118382 complement(3283849..3285897) 1 NC_011757.1 TIGRFAM: excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain protein; UvrB/UvrC protein; KEGG: mex:Mext_2878 excinuclease ABC, C subunit; excinuclease ABC subunit C 3285897 7118382 Mchl_3104 Methylobacterium extorquens CM4 excinuclease ABC subunit C YP_002421870.1 3283849 R 440085 CDS YP_002421871.1 218531055 7118383 complement(3285993..3286718) 1 NC_011757.1 KEGG: mex:Mext_2879 hypothetical protein; chemotaxis phosphatase, CheZ 3286718 7118383 Mchl_3105 Methylobacterium extorquens CM4 chemotaxis phosphatase, CheZ YP_002421871.1 3285993 R 440085 CDS YP_002421872.1 218531056 7118384 3286948..3287670 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2880 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3287670 7118384 Mchl_3106 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421872.1 3286948 D 440085 CDS YP_002421873.1 218531057 7118385 complement(3287750..3288481) 1 NC_011757.1 KEGG: mex:Mext_2881 periplasmic ligand-binding sensor protein; periplasmic ligand-binding sensor protein 3288481 7118385 Mchl_3107 Methylobacterium extorquens CM4 periplasmic ligand-binding sensor protein YP_002421873.1 3287750 R 440085 CDS YP_002421874.1 218531058 7118386 complement(3288810..3289682) 1 NC_011757.1 KEGG: mex:Mext_2882 porin; porin 3289682 7118386 Mchl_3108 Methylobacterium extorquens CM4 porin YP_002421874.1 3288810 R 440085 CDS YP_002421875.1 218531059 7118387 complement(3290079..3290846) 1 NC_011757.1 PFAM: protein of unknown function DUF152; KEGG: mex:Mext_2883 hypothetical protein; hypothetical protein 3290846 7118387 Mchl_3109 Methylobacterium extorquens CM4 hypothetical protein YP_002421875.1 3290079 R 440085 CDS YP_002421876.1 218531060 7118388 complement(3290887..3291972) 1 NC_011757.1 PFAM: protein of unknown function DUF185; KEGG: mex:Mext_2884 hypothetical protein; hypothetical protein 3291972 7118388 Mchl_3110 Methylobacterium extorquens CM4 hypothetical protein YP_002421876.1 3290887 R 440085 CDS YP_002421877.1 218531061 7118389 complement(3291975..3292865) 1 NC_011757.1 PFAM: prolipoprotein diacylglyceryl transferase; KEGG: mex:Mext_2885 prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 3292865 7118389 Mchl_3111 Methylobacterium extorquens CM4 prolipoprotein diacylglyceryl transferase YP_002421877.1 3291975 R 440085 CDS YP_002421878.1 218531062 7118390 3293007..3293687 1 NC_011757.1 PFAM: MgtC/SapB transporter; KEGG: mex:Mext_2886 MgtC/SapB transporter; MgtC/SapB transporter 3293687 7118390 Mchl_3112 Methylobacterium extorquens CM4 MgtC/SapB transporter YP_002421878.1 3293007 D 440085 CDS YP_002421879.1 218531063 7118842 3293791..3295422 1 NC_011757.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 3295422 7118842 Mchl_3113 Methylobacterium extorquens CM4 phosphoglucomutase YP_002421879.1 3293791 D 440085 CDS YP_002421880.1 218531064 7115840 3295419..3296690 1 NC_011757.1 KEGG: mex:Mext_2888 hypothetical protein; hypothetical protein 3296690 7115840 Mchl_3114 Methylobacterium extorquens CM4 hypothetical protein YP_002421880.1 3295419 D 440085 CDS YP_002421881.1 218531065 7114114 complement(3296864..3297769) 1 NC_011757.1 PFAM: cell wall hydrolase SleB; KEGG: mex:Mext_2889 cell wall hydrolase SleB; cell wall hydrolase SleB 3297769 7114114 Mchl_3115 Methylobacterium extorquens CM4 cell wall hydrolase SleB YP_002421881.1 3296864 R 440085 CDS YP_002421882.1 218531066 7114115 complement(3297876..3298133) 1 NC_011757.1 KEGG: mex:Mext_2890 hypothetical protein; hypothetical protein 3298133 7114115 Mchl_3116 Methylobacterium extorquens CM4 hypothetical protein YP_002421882.1 3297876 R 440085 CDS YP_002421883.1 218531067 7114116 complement(3298319..3300985) 1 NC_011757.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 3300985 7114116 Mchl_3117 Methylobacterium extorquens CM4 pyruvate phosphate dikinase YP_002421883.1 3298319 R 440085 CDS YP_002421884.1 218531068 7114117 complement(3301203..3301355) 1 NC_011757.1 KEGG: mex:Mext_2892 hypothetical protein; hypothetical protein 3301355 7114117 Mchl_3118 Methylobacterium extorquens CM4 hypothetical protein YP_002421884.1 3301203 R 440085 CDS YP_002421885.1 218531069 7114118 complement(3301593..3302270) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2893 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3302270 7114118 Mchl_3119 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421885.1 3301593 R 440085 CDS YP_002421886.1 218531070 7114119 3302457..3302900 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_2894 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 3302900 7114119 Mchl_3120 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002421886.1 3302457 D 440085 CDS YP_002421887.1 218531071 7114120 3302983..3303243 1 NC_011757.1 KEGG: mex:Mext_2895 hypothetical protein; hypothetical protein 3303243 7114120 Mchl_3121 Methylobacterium extorquens CM4 hypothetical protein YP_002421887.1 3302983 D 440085 CDS YP_002421888.1 218531072 7114121 complement(3303289..3303738) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_2896 cyclic nucleotide-binding; cyclic nucleotide-binding protein 3303738 7114121 Mchl_3122 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002421888.1 3303289 R 440085 CDS YP_002421889.1 218531073 7114122 complement(3303913..3304143) 1 NC_011757.1 KEGG: mpo:Mpop_3020 hypothetical protein; hypothetical protein 3304143 7114122 Mchl_3123 Methylobacterium extorquens CM4 hypothetical protein YP_002421889.1 3303913 R 440085 CDS YP_002421890.1 218531074 7114123 3304334..3304522 1 NC_011757.1 KEGG: mex:Mext_2898 hypothetical protein; hypothetical protein 3304522 7114123 Mchl_3124 Methylobacterium extorquens CM4 hypothetical protein YP_002421890.1 3304334 D 440085 CDS YP_002421891.1 218531075 7114124 complement(3304645..3305118) 1 NC_011757.1 PFAM: regulatory protein MarR; transcriptional regulator TrmB; KEGG: mex:Mext_2899 regulatory protein MarR; TrmB family transcriptional regulator 3305118 7114124 Mchl_3125 Methylobacterium extorquens CM4 TrmB family transcriptional regulator YP_002421891.1 3304645 R 440085 CDS YP_002421892.1 218531076 7114125 3305243..3306022 1 NC_011757.1 KEGG: mex:Mext_2900 hypothetical protein; hypothetical protein 3306022 7114125 Mchl_3126 Methylobacterium extorquens CM4 hypothetical protein YP_002421892.1 3305243 D 440085 CDS YP_002421893.1 218531077 7114126 complement(3306042..3306974) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_2901 beta-lactamase domain-containing protein; beta-lactamase 3306974 7114126 Mchl_3127 Methylobacterium extorquens CM4 beta-lactamase YP_002421893.1 3306042 R 440085 CDS YP_002421894.1 218531078 7114127 complement(3307054..3308082) 1 NC_011757.1 KEGG: mex:Mext_2902 hypothetical protein; hypothetical protein 3308082 7114127 Mchl_3128 Methylobacterium extorquens CM4 hypothetical protein YP_002421894.1 3307054 R 440085 CDS YP_002421895.1 218531079 7114128 3308782..3308958 1 NC_011757.1 PFAM: protein of unknown function DUF1328; KEGG: mex:Mext_2903 hypothetical protein; hypothetical protein 3308958 7114128 Mchl_3129 Methylobacterium extorquens CM4 hypothetical protein YP_002421895.1 3308782 D 440085 CDS YP_002421896.1 218531080 7114129 complement(3309037..3309258) 1 NC_011757.1 KEGG: mpo:Mpop_3028 hypothetical protein; hypothetical protein 3309258 7114129 Mchl_3130 Methylobacterium extorquens CM4 hypothetical protein YP_002421896.1 3309037 R 440085 CDS YP_002421897.1 218531081 7114130 3309438..3310241 1 NC_011757.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 3310241 7114130 Mchl_3131 Methylobacterium extorquens CM4 two-component response regulator YP_002421897.1 3309438 D 440085 CDS YP_002421898.1 218531082 7114131 3310701..3311063 1 NC_011757.1 KEGG: mex:Mext_2906 hypothetical protein; hypothetical protein 3311063 7114131 Mchl_3132 Methylobacterium extorquens CM4 hypothetical protein YP_002421898.1 3310701 D 440085 CDS YP_002421899.1 218531083 7114132 complement(3311160..3311699) 1 NC_011757.1 PFAM: protein of unknown function UPF0153; KEGG: mex:Mext_2907 hypothetical protein; hypothetical protein 3311699 7114132 Mchl_3133 Methylobacterium extorquens CM4 hypothetical protein YP_002421899.1 3311160 R 440085 CDS YP_002421900.1 218531084 7114133 3311822..3313213 1 NC_011757.1 PFAM: aminotransferase class-III; KEGG: mex:Mext_2908 aminotransferase class-III; class III aminotransferase 3313213 7114133 Mchl_3134 Methylobacterium extorquens CM4 class III aminotransferase YP_002421900.1 3311822 D 440085 CDS YP_002421901.1 218531085 7114134 3313560..3313775 1 NC_011757.1 KEGG: mex:Mext_2909 hypothetical protein; hypothetical protein 3313775 7114134 Mchl_3135 Methylobacterium extorquens CM4 hypothetical protein YP_002421901.1 3313560 D 440085 CDS YP_002421902.1 218531086 7114135 3313813..3314727 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_2910 metallophosphoesterase; metallophosphoesterase 3314727 7114135 Mchl_3136 Methylobacterium extorquens CM4 metallophosphoesterase YP_002421902.1 3313813 D 440085 CDS YP_002421903.1 218531087 7114136 complement(3314743..3314961) 1 NC_011757.1 KEGG: mex:Mext_2911 hypothetical protein; hypothetical protein 3314961 7114136 Mchl_3137 Methylobacterium extorquens CM4 hypothetical protein YP_002421903.1 3314743 R 440085 CDS YP_002421904.1 218531088 7114137 complement(3315018..3315455) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_2912 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 3315455 7114137 Mchl_3138 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002421904.1 3315018 R 440085 CDS YP_002421905.1 218531089 7114138 complement(3315452..3316378) 1 NC_011757.1 PFAM: HhH-GPD family protein; AlkA domain protein; KEGG: mex:Mext_2913 alcohol dehydrogenase; AlkA domain-containing protein 3316378 7114138 Mchl_3139 Methylobacterium extorquens CM4 AlkA domain-containing protein YP_002421905.1 3315452 R 440085 CDS YP_002421906.1 218531090 7114139 complement(3316428..3316715) 1 NC_011757.1 KEGG: mex:Mext_2914 hypothetical protein; hypothetical protein 3316715 7114139 Mchl_3140 Methylobacterium extorquens CM4 hypothetical protein YP_002421906.1 3316428 R 440085 CDS YP_002421907.1 218531091 7114140 complement(3316877..3318031) 1 NC_011757.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: mex:Mext_2915 ribonuclease D; ribonuclease D 3318031 7114140 Mchl_3141 Methylobacterium extorquens CM4 ribonuclease D YP_002421907.1 3316877 R 440085 CDS YP_002421908.1 218531092 7114141 complement(3318127..3318516) 1 NC_011757.1 KEGG: mex:Mext_2916 hypothetical protein; hypothetical protein 3318516 7114141 Mchl_3142 Methylobacterium extorquens CM4 hypothetical protein YP_002421908.1 3318127 R 440085 CDS YP_002421909.1 218531093 7114142 3318686..3319942 1 NC_011757.1 PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: mex:Mext_2917 serine-type D-Ala-D-Ala carboxypeptidase; serine-type D-Ala-D-Ala carboxypeptidase 3319942 7114142 Mchl_3143 Methylobacterium extorquens CM4 serine-type D-Ala-D-Ala carboxypeptidase YP_002421909.1 3318686 D 440085 CDS YP_002421910.1 218531094 7114143 complement(3319982..3321880) 1 NC_011757.1 PFAM: AsmA family protein; KEGG: mex:Mext_2918 AsmA family protein; AsmA family protein 3321880 7114143 Mchl_3144 Methylobacterium extorquens CM4 AsmA family protein YP_002421910.1 3319982 R 440085 CDS YP_002421911.1 218531095 7114144 3322266..3323003 1 NC_011757.1 KEGG: mex:Mext_2919 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase subunit alpha; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit alpha 3323003 7114144 Mchl_3145 Methylobacterium extorquens CM4 3-oxoacid CoA-transferase subunit alpha YP_002421911.1 3322266 D 440085 CDS YP_002421912.1 218531096 7114145 3323112..3323771 1 NC_011757.1 KEGG: mex:Mext_2920 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase subunit beta; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit beta 3323771 7114145 Mchl_3146 Methylobacterium extorquens CM4 3-oxoacid CoA-transferase subunit beta YP_002421912.1 3323112 D 440085 CDS YP_002421913.1 218531097 7114146 3323943..3324350 1 NC_011757.1 KEGG: mex:Mext_2921 hypothetical protein; hypothetical protein 3324350 7114146 Mchl_3147 Methylobacterium extorquens CM4 hypothetical protein YP_002421913.1 3323943 D 440085 CDS YP_002421914.1 218531098 7114147 3324940..3326322 1 NC_011757.1 PFAM: PepSY-associated TM helix domain protein; KEGG: mex:Mext_2923 PepSY-associated TM helix domain-containing protein; PepSY-associated TM helix domain-containing protein 3326322 7114147 Mchl_3148 Methylobacterium extorquens CM4 PepSY-associated TM helix domain-containing protein YP_002421914.1 3324940 D 440085 CDS YP_002421915.1 218531099 7114148 3326383..3328713 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_2924 TonB-dependent receptor; TonB-dependent receptor 3328713 7114148 Mchl_3149 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002421915.1 3326383 D 440085 CDS YP_002421916.1 218531100 7114149 complement(3328795..3329751) 1 NC_011757.1 KEGG: mex:Mext_2925 hypothetical protein; hypothetical protein 3329751 7114149 Mchl_3150 Methylobacterium extorquens CM4 hypothetical protein YP_002421916.1 3328795 R 440085 CDS YP_002421917.1 218531101 7114150 complement(3329726..3330541) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_2926 ABC transporter; ABC transporter 3330541 7114150 Mchl_3151 Methylobacterium extorquens CM4 ABC transporter YP_002421917.1 3329726 R 440085 CDS YP_002421918.1 218531102 7114151 complement(3330538..3331578) 1 NC_011757.1 PFAM: transporter permease; KEGG: mex:Mext_2927 transporter permease; transporter permease 3331578 7114151 Mchl_3152 Methylobacterium extorquens CM4 transporter permease YP_002421918.1 3330538 R 440085 CDS YP_002421919.1 218531103 7114152 complement(3331575..3332408) 1 NC_011757.1 PFAM: periplasmic binding protein; KEGG: mex:Mext_2928 periplasmic binding protein; periplasmic binding protein 3332408 7114152 Mchl_3153 Methylobacterium extorquens CM4 periplasmic binding protein YP_002421919.1 3331575 R 440085 CDS YP_002421920.1 218531104 7114153 3332739..3333029 1 NC_011757.1 TIGRFAM: addiction module killer protein; PFAM: protein of unknown function DUF891; KEGG: xfn:XfasM23_1253 addiction module killer protein; addiction module killer protein 3333029 7114153 Mchl_3154 Methylobacterium extorquens CM4 addiction module killer protein YP_002421920.1 3332739 D 440085 CDS YP_002421921.1 218531105 7114154 3333032..3333331 1 NC_011757.1 TIGRFAM: addiction module antidote protein; KEGG: mpo:Mpop_4949 transcriptional regulator; transcriptional regulator 3333331 7114154 Mchl_3155 Methylobacterium extorquens CM4 transcriptional regulator YP_002421921.1 3333032 D 440085 CDS YP_002421922.1 218531106 7114155 complement(3333353..3334918) 1 NC_011757.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3334918 guaA 7114155 guaA Methylobacterium extorquens CM4 GMP synthase YP_002421922.1 3333353 R 440085 CDS YP_002421923.1 218531107 7114156 3335088..3335315 1 NC_011757.1 KEGG: mpo:Mpop_3114 hypothetical protein; hypothetical protein 3335315 7114156 Mchl_3157 Methylobacterium extorquens CM4 hypothetical protein YP_002421923.1 3335088 D 440085 CDS YP_002421924.1 218531108 7114157 complement(3335501..3336112) 1 NC_011757.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: mex:Mext_2932 phosphoesterase PA-phosphatase related; PA-phosphatase-like phosphoesterase 3336112 7114157 Mchl_3158 Methylobacterium extorquens CM4 PA-phosphatase-like phosphoesterase YP_002421924.1 3335501 R 440085 CDS YP_002421925.1 218531109 7114158 complement(3336223..3337251) 1 NC_011757.1 KEGG: mex:Mext_2933 hypothetical protein; hypothetical protein 3337251 7114158 Mchl_3159 Methylobacterium extorquens CM4 hypothetical protein YP_002421925.1 3336223 R 440085 CDS YP_002421926.1 218531110 7114159 complement(3337387..3338736) 1 NC_011757.1 PFAM: Fmu (Sun) domain protein; KEGG: mex:Mext_2934 Fmu (Sun) domain-containing protein; Fmu (Sun) domain-containing protein 3338736 7114159 Mchl_3160 Methylobacterium extorquens CM4 Fmu (Sun) domain-containing protein YP_002421926.1 3337387 R 440085 CDS YP_002421927.1 218531111 7114160 3338832..3339020 1 NC_011757.1 KEGG: mex:Mext_2935 hypothetical protein; hypothetical protein 3339020 7114160 Mchl_3161 Methylobacterium extorquens CM4 hypothetical protein YP_002421927.1 3338832 D 440085 CDS YP_002421928.1 218531112 7114161 complement(3339124..3340062) 1 NC_011757.1 KEGG: mex:Mext_2936 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; 2-dehydropantoate 2-reductase 3340062 7114161 Mchl_3162 Methylobacterium extorquens CM4 2-dehydropantoate 2-reductase YP_002421928.1 3339124 R 440085 CDS YP_002421929.1 218531113 7114162 3340269..3341153 1 NC_011757.1 KEGG: mex:Mext_2937 hypothetical protein; hypothetical protein 3341153 7114162 Mchl_3163 Methylobacterium extorquens CM4 hypothetical protein YP_002421929.1 3340269 D 440085 CDS YP_002421930.1 218531114 7114163 3341478..3342323 1 NC_011757.1 KEGG: mex:Mext_2938 hypothetical protein; hypothetical protein 3342323 7114163 Mchl_3164 Methylobacterium extorquens CM4 hypothetical protein YP_002421930.1 3341478 D 440085 CDS YP_002421931.1 218531115 7114164 3342605..3342724 1 NC_011757.1 KEGG: mpo:Mpop_3121 hypothetical protein; hypothetical protein 3342724 7114164 Mchl_3165 Methylobacterium extorquens CM4 hypothetical protein YP_002421931.1 3342605 D 440085 CDS YP_002421932.1 218531116 7114165 complement(3342852..3344342) 1 NC_011757.1 KEGG: mex:Mext_2939 inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase; inosine-5'-monophosphate dehydrogenase 3344342 7114165 Mchl_3166 Methylobacterium extorquens CM4 inosine-5'-monophosphate dehydrogenase YP_002421932.1 3342852 R 440085 CDS YP_002421933.1 218531117 7114166 3344606..3345772 1 NC_011757.1 PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; cell cycle protein 3345772 7114166 Mchl_3167 Methylobacterium extorquens CM4 cell cycle protein YP_002421933.1 3344606 D 440085 CDS YP_002421934.1 218531118 7114167 3345769..3346878 1 NC_011757.1 KEGG: mex:Mext_2941 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyl transferase family 28; glycosyltransferase 28 domain; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3346878 7114167 Mchl_3168 Methylobacterium extorquens CM4 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase YP_002421934.1 3345769 D 440085 CDS YP_002421935.1 218531119 7114168 3347020..3348426 1 NC_011757.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 3348426 murC 7114168 murC Methylobacterium extorquens CM4 UDP-N-acetylmuramate--L-alanine ligase YP_002421935.1 3347020 D 440085 CDS YP_002421936.1 218531120 7114169 complement(3348443..3348832) 1 NC_011757.1 KEGG: mex:Mext_2943 phage-related transcriptional regulator; phage-related transcriptional regulator 3348832 7114169 Mchl_3170 Methylobacterium extorquens CM4 phage-related transcriptional regulator YP_002421936.1 3348443 R 440085 CDS YP_002421937.1 218531121 7114170 complement(3348843..3349049) 1 NC_011757.1 KEGG: mex:Mext_2944 hypothetical protein; hypothetical protein 3349049 7114170 Mchl_3171 Methylobacterium extorquens CM4 hypothetical protein YP_002421937.1 3348843 R 440085 CDS YP_002421938.1 218531122 7114171 3349145..3350074 1 NC_011757.1 KEGG: mex:Mext_2945 UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD linked oxidase domain protein; UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; UDP-N-acetylenolpyruvoylglucosamine reductase 3350074 7114171 Mchl_3172 Methylobacterium extorquens CM4 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002421938.1 3349145 D 440085 CDS YP_002421939.1 218531123 7114172 3350118..3351041 1 NC_011757.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 3351041 ddl 7114172 ddl Methylobacterium extorquens CM4 D-alanine--D-alanine ligase YP_002421939.1 3350118 D 440085 CDS YP_002421940.1 218531124 7114173 3351008..3351946 1 NC_011757.1 PFAM: cell division protein FtsQ; polypeptide-transport-associated domain protein FtsQ-type; KEGG: mex:Mext_2947 polypeptide-transport-associated domain-containing protein; cell division protein FtsQ 3351946 7114173 Mchl_3174 Methylobacterium extorquens CM4 cell division protein FtsQ YP_002421940.1 3351008 D 440085 CDS YP_002421941.1 218531125 7114174 3352009..3353331 1 NC_011757.1 PFAM: cell division protein FtsA; KEGG: mpo:Mpop_3132 cell division protein FtsA; cell division protein FtsA 3353331 7114174 Mchl_3175 Methylobacterium extorquens CM4 cell division protein FtsA YP_002421941.1 3352009 D 440085 CDS YP_002421942.1 218531126 7114175 3353537..3355294 1 NC_011757.1 TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: mex:Mext_2949 cell division protein FtsZ; cell division protein FtsZ 3355294 7114175 Mchl_3176 Methylobacterium extorquens CM4 cell division protein FtsZ YP_002421942.1 3353537 D 440085 CDS YP_002421943.1 218531127 7114176 3355645..3356592 1 NC_011757.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3356592 lpxC 7114176 lpxC Methylobacterium extorquens CM4 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002421943.1 3355645 D 440085 CDS YP_002421944.1 218531128 7114177 3356758..3357633 1 NC_011757.1 TIGRFAM: outer membrane assembly lipoprotein YfiO; KEGG: mex:Mext_2951 lipoprotein; outer membrane assembly lipoprotein YfiO 3357633 7114177 Mchl_3178 Methylobacterium extorquens CM4 outer membrane assembly lipoprotein YfiO YP_002421944.1 3356758 D 440085 CDS YP_002421945.1 218531129 7114178 complement(3357902..3358888) 1 NC_011757.1 KEGG: mex:Mext_2953 hypothetical protein; hypothetical protein 3358888 7114178 Mchl_3179 Methylobacterium extorquens CM4 hypothetical protein YP_002421945.1 3357902 R 440085 CDS YP_002421946.1 218531130 7114179 3359055..3360755 1 NC_011757.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: mex:Mext_2954 DNA repair protein RecN; DNA repair protein RecN 3360755 7114179 Mchl_3180 Methylobacterium extorquens CM4 DNA repair protein RecN YP_002421946.1 3359055 D 440085 CDS YP_002421947.1 218531131 7114180 complement(3360916..3361209) 1 NC_011757.1 KEGG: mpo:Mpop_3139 hypothetical protein; hypothetical protein 3361209 7114180 Mchl_3181 Methylobacterium extorquens CM4 hypothetical protein YP_002421947.1 3360916 R 440085 CDS YP_002421948.1 218531132 7114181 complement(3361293..3361565) 1 NC_011757.1 PFAM: YiaAB two helix domain protein; KEGG: mex:Mext_2956 YiaAB two helix domain-containing protein; YiaAB helix domain-containing protein 3361565 7114181 Mchl_3182 Methylobacterium extorquens CM4 YiaAB helix domain-containing protein YP_002421948.1 3361293 R 440085 CDS YP_002421949.1 218531133 7114182 complement(3361597..3362289) 1 NC_011757.1 PFAM: PspA/IM30 family protein; KEGG: mex:Mext_2957 PspA/IM30 family protein; phage shock protein PspA 3362289 7114182 Mchl_3183 Methylobacterium extorquens CM4 phage shock protein PspA YP_002421949.1 3361597 R 440085 CDS YP_002421950.1 218531134 7114183 complement(3362431..3364746) 1 NC_011757.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: mex:Mext_2958 oxidoreductase alpha (molybdopterin) subunit; oxidoreductase alpha (molybdopterin) subunit 3364746 7114183 Mchl_3184 Methylobacterium extorquens CM4 oxidoreductase alpha (molybdopterin) subunit YP_002421950.1 3362431 R 440085 CDS YP_002421951.1 218531135 7114184 complement(3364849..3365925) 1 NC_011757.1 KEGG: mex:Mext_2959 hypothetical protein; hypothetical protein 3365925 7114184 Mchl_3185 Methylobacterium extorquens CM4 hypothetical protein YP_002421951.1 3364849 R 440085 CDS YP_002421952.1 218531136 7114185 3366271..3368190 1 NC_011757.1 KEGG: mex:Mext_2960 chaperone protein DnaK; TIGRFAM: chaperone protein DnaK; PFAM: heat shock protein 70; chaperone protein DnaK 3368190 7114185 Mchl_3186 Methylobacterium extorquens CM4 chaperone protein DnaK YP_002421952.1 3366271 D 440085 CDS YP_002421953.1 218531137 7114186 3368442..3369599 1 NC_011757.1 TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: mex:Mext_2961 chaperone protein DnaJ; chaperone protein DnaJ 3369599 7114186 Mchl_3187 Methylobacterium extorquens CM4 chaperone protein DnaJ YP_002421953.1 3368442 D 440085 CDS YP_002421954.1 218531138 7114187 3369758..3370414 1 NC_011757.1 KEGG: mex:Mext_2962 phospholipid N-methyltransferase; phospholipid N-methyltransferase 3370414 7114187 Mchl_3188 Methylobacterium extorquens CM4 phospholipid N-methyltransferase YP_002421954.1 3369758 D 440085 CDS YP_002421955.1 218531139 7114188 3370680..3371006 1 NC_011757.1 KEGG: mex:Mext_2963 hypothetical protein; hypothetical protein 3371006 7114188 Mchl_3189 Methylobacterium extorquens CM4 hypothetical protein YP_002421955.1 3370680 D 440085 CDS YP_002421956.1 218531140 7114189 complement(3371033..3372343) 1 NC_011757.1 KEGG: mex:Mext_2964 thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; thymidine phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; glycosyl transferase, family 3-like; thymidine phosphorylase 3372343 7114189 Mchl_3190 Methylobacterium extorquens CM4 thymidine phosphorylase YP_002421956.1 3371033 R 440085 CDS YP_002421957.1 218531141 7114190 complement(3372340..3373113) 1 NC_011757.1 KEGG: mex:Mext_2965 deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; deoxyribose-phosphate aldolase 3373113 7114190 Mchl_3191 Methylobacterium extorquens CM4 deoxyribose-phosphate aldolase YP_002421957.1 3372340 R 440085 CDS YP_002421958.1 218531142 7114191 complement(3373123..3373935) 1 NC_011757.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 3373935 7114191 Mchl_3192 Methylobacterium extorquens CM4 purine nucleoside phosphorylase YP_002421958.1 3373123 R 440085 CDS YP_002421959.1 218531143 7114192 complement(3373925..3374338) 1 NC_011757.1 TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: mex:Mext_2967 cytidine deaminase; cytidine deaminase 3374338 7114192 Mchl_3193 Methylobacterium extorquens CM4 cytidine deaminase YP_002421959.1 3373925 R 440085 CDS YP_002421960.1 218531144 7114193 3374483..3374707 1 NC_011757.1 KEGG: mex:Mext_2968 hypothetical protein; hypothetical protein 3374707 7114193 Mchl_3194 Methylobacterium extorquens CM4 hypothetical protein YP_002421960.1 3374483 D 440085 CDS YP_002421961.1 218531145 7114194 complement(3374790..3375773) 1 NC_011757.1 KEGG: mex:Mext_2969 tetraacyldisaccharide 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; tetraacyldisaccharide 4'-kinase 3375773 7114194 Mchl_3195 Methylobacterium extorquens CM4 tetraacyldisaccharide 4'-kinase YP_002421961.1 3374790 R 440085 CDS YP_002421962.1 218531146 7117373 complement(3375781..3377085) 1 NC_011757.1 PFAM: 3-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: mex:Mext_2970 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein 3377085 7117373 Mchl_3196 Methylobacterium extorquens CM4 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein YP_002421962.1 3375781 R 440085 CDS YP_002421963.1 218531147 7117536 complement(3377082..3377831) 1 NC_011757.1 PFAM: protein of unknown function DUF374; KEGG: mex:Mext_2971 hypothetical protein; hypothetical protein 3377831 7117536 Mchl_3197 Methylobacterium extorquens CM4 hypothetical protein YP_002421963.1 3377082 R 440085 CDS YP_002421964.1 218531148 7117537 3378069..3379016 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_2972 metallophosphoesterase; metallophosphoesterase 3379016 7117537 Mchl_3198 Methylobacterium extorquens CM4 metallophosphoesterase YP_002421964.1 3378069 D 440085 CDS YP_002421965.1 218531149 7117538 complement(3379032..3379508) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_2973 response regulator receiver; response regulator receiver protein 3379508 7117538 Mchl_3199 Methylobacterium extorquens CM4 response regulator receiver protein YP_002421965.1 3379032 R 440085 CDS YP_002421966.1 218531150 7117539 3379890..3380729 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_2974 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 3380729 7117539 Mchl_3200 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002421966.1 3379890 D 440085 CDS YP_002421967.1 218531151 7117540 3380857..3381102 1 NC_011757.1 KEGG: mex:Mext_2975 hypothetical protein; hypothetical protein 3381102 7117540 Mchl_3201 Methylobacterium extorquens CM4 hypothetical protein YP_002421967.1 3380857 D 440085 CDS YP_002421968.1 218531152 7117541 complement(3381162..3382571) 1 NC_011757.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: mex:Mext_2976 leucyl aminopeptidase; leucyl aminopeptidase 3382571 7117541 Mchl_3202 Methylobacterium extorquens CM4 leucyl aminopeptidase YP_002421968.1 3381162 R 440085 CDS YP_002421969.1 218531153 7117542 3382669..3383517 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_4; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: mex:Mext_2977 hypotheticalprotein; hypothetical protein 3383517 7117542 Mchl_3203 Methylobacterium extorquens CM4 hypothetical protein YP_002421969.1 3382669 D 440085 CDS YP_002421970.1 218531154 7117543 3383703..3384008 1 NC_011757.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3384008 rpmB 7117543 rpmB Methylobacterium extorquens CM4 50S ribosomal protein L28 YP_002421970.1 3383703 D 440085 CDS YP_002421971.1 218531155 7117544 3384122..3385051 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_2979 auxin efflux carrier; hypothetical protein 3385051 7117544 Mchl_3205 Methylobacterium extorquens CM4 hypothetical protein YP_002421971.1 3384122 D 440085 CDS YP_002421972.1 218531156 7117545 3385205..3386908 1 NC_011757.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 3386908 lysK 7117545 lysK Methylobacterium extorquens CM4 lysyl-tRNA synthetase YP_002421972.1 3385205 D 440085 CDS YP_002421973.1 218531157 7117546 complement(3387055..3387609) 1 NC_011757.1 KEGG: mex:Mext_2981 hypothetical protein; hypothetical protein 3387609 7117546 Mchl_3207 Methylobacterium extorquens CM4 hypothetical protein YP_002421973.1 3387055 R 440085 CDS YP_002421974.1 218531158 7117547 3387789..3388754 1 NC_011757.1 TIGRFAM: peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; KEGG: mex:Mext_2982 peptide chain release factor 2; peptide chain release factor 2 3388754 7117547 Mchl_3208 Methylobacterium extorquens CM4 peptide chain release factor 2 YP_002421974.1 3387789 D 440085 CDS YP_002421975.1 218531159 7117548 complement(3388899..3390077) 1 NC_011757.1 PFAM: peptidase M23; KEGG: mex:Mext_2983 peptidase M23B; peptidase M23 3390077 7117548 Mchl_3209 Methylobacterium extorquens CM4 peptidase M23 YP_002421975.1 3388899 R 440085 CDS YP_002421976.1 218531160 7117549 complement(3390252..3390719) 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: mex:Mext_2984 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen 3390719 7117549 Mchl_3210 Methylobacterium extorquens CM4 alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen YP_002421976.1 3390252 R 440085 CDS YP_002421977.1 218531161 7117550 3390870..3394325 1 NC_011757.1 KEGG: mex:Mext_2985 hypothetical protein; hypothetical protein 3394325 7117550 Mchl_3211 Methylobacterium extorquens CM4 hypothetical protein YP_002421977.1 3390870 D 440085 CDS YP_002421978.1 218531162 7117551 3394930..3396006 1 NC_011757.1 PFAM: fatty acid desaturase; KEGG: mex:Mext_2986 fatty acid desaturase; fatty acid desaturase 3396006 7117551 Mchl_3212 Methylobacterium extorquens CM4 fatty acid desaturase YP_002421978.1 3394930 D 440085 CDS YP_002421979.1 218531163 7117552 complement(3396072..3397343) 1 NC_011757.1 KEGG: mex:Mext_2987 tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; tyrosyl-tRNA synthetase 3397343 7117552 Mchl_3213 Methylobacterium extorquens CM4 tyrosyl-tRNA synthetase YP_002421979.1 3396072 R 440085 CDS YP_002421980.1 218531164 7117553 3397484..3398617 1 NC_011757.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 3398617 anmK 7117553 anmK Methylobacterium extorquens CM4 anhydro-N-acetylmuramic acid kinase YP_002421980.1 3397484 D 440085 CDS YP_002421981.1 218531165 7117554 3398627..3399220 1 NC_011757.1 KEGG: mex:Mext_2989 hypothetical protein; hypothetical protein 3399220 7117554 Mchl_3215 Methylobacterium extorquens CM4 hypothetical protein YP_002421981.1 3398627 D 440085 CDS YP_002421982.1 218531166 7117555 3399286..3400386 1 NC_011757.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3400386 7117555 Mchl_3216 Methylobacterium extorquens CM4 chorismate synthase YP_002421982.1 3399286 D 440085 CDS YP_002421983.1 218531167 7117556 3400515..3401594 1 NC_011757.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: mex:Mext_2991 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3401594 7117556 Mchl_3217 Methylobacterium extorquens CM4 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002421983.1 3400515 D 440085 CDS YP_002421984.1 218531168 7117557 complement(3401700..3402629) 1 NC_011757.1 PFAM: histone deacetylase superfamily; KEGG: mex:Mext_2993 histone deacetylase superfamily protein; histone deacetylase superfamily protein 3402629 7117557 Mchl_3218 Methylobacterium extorquens CM4 histone deacetylase superfamily protein YP_002421984.1 3401700 R 440085 CDS YP_002421985.1 218531169 7117558 3402930..3403568 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_2994 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3403568 7117558 Mchl_3219 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002421985.1 3402930 D 440085 CDS YP_002421986.1 218531170 7117559 3403684..3404199 1 NC_011757.1 KEGG: mex:Mext_2995 hypothetical protein; hypothetical protein 3404199 7117559 Mchl_3220 Methylobacterium extorquens CM4 hypothetical protein YP_002421986.1 3403684 D 440085 CDS YP_002421987.1 218531171 7117560 3404427..3406430 1 NC_011757.1 PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: mex:Mext_2996 carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthase L chain ATP-binding 3406430 7117560 Mchl_3221 Methylobacterium extorquens CM4 carbamoyl-phosphate synthase L chain ATP-binding YP_002421987.1 3404427 D 440085 CDS YP_002421988.1 218531172 7117561 3406619..3407050 1 NC_011757.1 PFAM: AIG2 family protein; KEGG: mex:Mext_2997 AIG2 family protein; AIG2 family protein 3407050 7117561 Mchl_3222 Methylobacterium extorquens CM4 AIG2 family protein YP_002421988.1 3406619 D 440085 CDS YP_002421989.1 218531173 7117562 3407324..3407608 1 NC_011757.1 PFAM: acylphosphatase; KEGG: mex:Mext_2998 acylphosphatase; acylphosphatase 3407608 7117562 Mchl_3223 Methylobacterium extorquens CM4 acylphosphatase YP_002421989.1 3407324 D 440085 CDS YP_002421990.1 218531174 7117563 3407710..3408423 1 NC_011757.1 PFAM: protein of unknown function DUF599; KEGG: mex:Mext_2999 hypothetical protein; hypothetical protein 3408423 7117563 Mchl_3224 Methylobacterium extorquens CM4 hypothetical protein YP_002421990.1 3407710 D 440085 CDS YP_002421991.1 218531175 7117564 3408413..3408676 1 NC_011757.1 KEGG: mex:Mext_3000 hypothetical protein; hypothetical protein 3408676 7117564 Mchl_3225 Methylobacterium extorquens CM4 hypothetical protein YP_002421991.1 3408413 D 440085 CDS YP_002421992.1 218531176 7117565 complement(3408684..3409481) 1 NC_011757.1 PFAM: protein of unknown function DUF218; KEGG: mex:Mext_3001 hypothetical protein; hypothetical protein 3409481 7117565 Mchl_3226 Methylobacterium extorquens CM4 hypothetical protein YP_002421992.1 3408684 R 440085 CDS YP_002421993.1 218531177 7117566 complement(3409543..3410166) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_3002 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 3410166 7117566 Mchl_3227 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002421993.1 3409543 R 440085 CDS YP_002421994.1 218531178 7117567 complement(3410163..3411224) 1 NC_011757.1 KEGG: mex:Mext_3003 lysine 2,3-aminomutase YodO family protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 3411224 7117567 Mchl_3228 Methylobacterium extorquens CM4 lysine 2,3-aminomutase YodO family protein YP_002421994.1 3410163 R 440085 CDS YP_002421995.1 218531179 7117568 complement(3411221..3412279) 1 NC_011757.1 PFAM: tRNA synthetase class II (D K and N); KEGG: mex:Mext_3004 tRNA synthetase class II (D K and N); tRNA synthetase class II (D K and N) 3412279 7117568 Mchl_3229 Methylobacterium extorquens CM4 tRNA synthetase class II (D K and N) YP_002421995.1 3411221 R 440085 CDS YP_002421996.1 218531180 7117569 3412403..3412969 1 NC_011757.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 3412969 7117569 Mchl_3230 Methylobacterium extorquens CM4 elongation factor P YP_002421996.1 3412403 D 440085 CDS YP_002421997.1 218531181 7117570 complement(3413145..3414131) 1 NC_011757.1 PFAM: protein of unknown function DUF1624; KEGG: mex:Mext_3006 hypothetical protein; hypothetical protein 3414131 7117570 Mchl_3231 Methylobacterium extorquens CM4 hypothetical protein YP_002421997.1 3413145 R 440085 CDS YP_002421998.1 218531182 7117571 3414554..3415099 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_3007 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 3415099 7117571 Mchl_3232 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002421998.1 3414554 D 440085 CDS YP_002421999.1 218531183 7117572 3415096..3415626 1 NC_011757.1 PFAM: protein of unknown function DUF192; KEGG: mex:Mext_3008 hypothetical protein; hypothetical protein 3415626 7117572 Mchl_3233 Methylobacterium extorquens CM4 hypothetical protein YP_002421999.1 3415096 D 440085 CDS YP_002422000.1 218531184 7117574 3417369..3418274 1 NC_011757.1 TIGRFAM: magnesium chelatase accessory protein; PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3010 magnesium chelatase accessory protein; magnesium chelatase accessory protein 3418274 7117574 Mchl_3235 Methylobacterium extorquens CM4 magnesium chelatase accessory protein YP_002422000.1 3417369 D 440085 CDS YP_002422001.1 218531185 7117575 3418319..3419845 1 NC_011757.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_3011 phytoene desaturase; phytoene desaturase 3419845 7117575 Mchl_3236 Methylobacterium extorquens CM4 phytoene desaturase YP_002422001.1 3418319 D 440085 CDS YP_002422002.1 218531186 7117576 3419826..3420884 1 NC_011757.1 PFAM: Squalene/phytoene synthase; KEGG: mex:Mext_3012 squalene/phytoene synthase; Squalene/phytoene synthase 3420884 7117576 Mchl_3237 Methylobacterium extorquens CM4 Squalene/phytoene synthase YP_002422002.1 3419826 D 440085 CDS YP_002422003.1 218531187 7117577 complement(3421158..3421772) 1 NC_011757.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: mex:Mext_3013 urease accessory protein UreG; urease accessory protein UreG 3421772 7117577 Mchl_3238 Methylobacterium extorquens CM4 urease accessory protein UreG YP_002422003.1 3421158 R 440085 CDS YP_002422004.1 218531188 7117578 complement(3421788..3422504) 1 NC_011757.1 PFAM: urease accessory protein UreF; KEGG: mex:Mext_3014 urease accessory protein UreF; urease accessory protein UreF 3422504 7117578 Mchl_3239 Methylobacterium extorquens CM4 urease accessory protein UreF YP_002422004.1 3421788 R 440085 CDS YP_002422005.1 218531189 7117579 complement(3422455..3422946) 1 NC_011757.1 PFAM: urease accessory protein UreE; KEGG: mex:Mext_3015 UreE urease accessory domain-containing protein; urease accessory protein UreE 3422946 7117579 Mchl_3240 Methylobacterium extorquens CM4 urease accessory protein UreE YP_002422005.1 3422455 R 440085 CDS YP_002422006.1 218531190 7117580 complement(3422951..3423436) 1 NC_011757.1 PFAM: protein of unknown function DUF29; KEGG: npu:Npun_R4412 hypothetical protein; hypothetical protein 3423436 7117580 Mchl_3241 Methylobacterium extorquens CM4 hypothetical protein YP_002422006.1 3422951 R 440085 CDS YP_002422007.1 218531191 7117581 complement(3423469..3425196) 1 NC_011757.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 3425196 ureC 7117581 ureC Methylobacterium extorquens CM4 urease subunit alpha YP_002422007.1 3423469 R 440085 CDS YP_002422008.1 218531192 7117582 complement(3425199..3425759) 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_3018 metal-dependent phosphohydrolase; metal dependent phosphohydrolase 3425759 7117582 Mchl_3243 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002422008.1 3425199 R 440085 CDS YP_002422009.1 218531193 7117583 complement(3425756..3426376) 1 NC_011757.1 KEGG: mex:Mext_3019 urease subunit gamma; TIGRFAM: urease subunit beta; urease subunit gamma; PFAM: urease subunit beta; urease subunit gamma region; urease subunit gamma 3426376 7117583 Mchl_3244 Methylobacterium extorquens CM4 urease subunit gamma YP_002422009.1 3425756 R 440085 CDS YP_002422010.1 218531194 7117584 complement(3426457..3427386) 1 NC_011757.1 PFAM: urease accessory protein UreD; KEGG: mex:Mext_3020 urease accessory protein UreD; urease accessory protein UreD 3427386 7117584 Mchl_3245 Methylobacterium extorquens CM4 urease accessory protein UreD YP_002422010.1 3426457 R 440085 CDS YP_002422011.1 218531195 7117585 3427596..3428114 1 NC_011757.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: mex:Mext_3021 flavin reductase domain-containing protein; flavin reductase domain-containing FMN-binding protein 3428114 7117585 Mchl_3246 Methylobacterium extorquens CM4 flavin reductase domain-containing FMN-binding protein YP_002422011.1 3427596 D 440085 CDS YP_002422012.1 218531196 7117586 complement(3428273..3428521) 1 NC_011757.1 KEGG: mex:Mext_3022 hypothetical protein; hypothetical protein 3428521 7117586 Mchl_3247 Methylobacterium extorquens CM4 hypothetical protein YP_002422012.1 3428273 R 440085 CDS YP_002422013.1 218531197 7117587 complement(3429134..3430492) 1 NC_011757.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.; hydroxydechloroatrazine ethylaminohydrolase 3430492 7117587 Mchl_3248 Methylobacterium extorquens CM4 hydroxydechloroatrazine ethylaminohydrolase YP_002422013.1 3429134 R 440085 CDS YP_002422014.1 218531198 7117588 3430870..3431490 1 NC_011757.1 KEGG: mex:Mext_3025 hypothetical protein; hypothetical protein 3431490 7117588 Mchl_3249 Methylobacterium extorquens CM4 hypothetical protein YP_002422014.1 3430870 D 440085 CDS YP_002422015.1 218531199 7117589 complement(3431567..3431800) 1 NC_011757.1 KEGG: mex:Mext_3026 hypothetical protein; hypothetical protein 3431800 7117589 Mchl_3250 Methylobacterium extorquens CM4 hypothetical protein YP_002422015.1 3431567 R 440085 CDS YP_002422016.1 218531200 7117590 3432356..3433369 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3027 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 3433369 7117590 Mchl_3251 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002422016.1 3432356 D 440085 CDS YP_002422017.1 218531201 7117591 3433603..3434919 1 NC_011757.1 KEGG: mex:Mext_3028 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; nucleotide sugar dehydrogenase 3434919 7117591 Mchl_3252 Methylobacterium extorquens CM4 nucleotide sugar dehydrogenase YP_002422017.1 3433603 D 440085 CDS YP_002422018.1 218531202 7117592 complement(3434975..3435319) 1 NC_011757.1 KEGG: mex:Mext_3029 hypothetical protein; hypothetical protein 3435319 7117592 Mchl_3253 Methylobacterium extorquens CM4 hypothetical protein YP_002422018.1 3434975 R 440085 CDS YP_002422019.1 218531203 7117593 3435877..3436104 1 NC_011757.1 KEGG: mex:Mext_3030 hypothetical protein; hypothetical protein 3436104 7117593 Mchl_3254 Methylobacterium extorquens CM4 hypothetical protein YP_002422019.1 3435877 D 440085 CDS YP_002422020.1 218531204 7117594 3436415..3436687 1 NC_011757.1 KEGG: mex:Mext_3031 hypothetical protein; hypothetical protein 3436687 7117594 Mchl_3255 Methylobacterium extorquens CM4 hypothetical protein YP_002422020.1 3436415 D 440085 CDS YP_002422021.1 218531205 7117595 complement(3436758..3438290) 1 NC_011757.1 TIGRFAM: threonine dehydratase, biosynthetic; PFAM: threonine dehydratase domain protein; pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: mex:Mext_3032 threonine dehydratase, biosynthetic; threonine dehydratase, biosynthetic 3438290 7117595 Mchl_3256 Methylobacterium extorquens CM4 threonine dehydratase, biosynthetic YP_002422021.1 3436758 R 440085 CDS YP_002422022.1 218531206 7117596 complement(3438391..3438981) 1 NC_011757.1 PFAM: type IV pilus assembly PilZ; KEGG: mex:Mext_3033 type IV pilus assembly PilZ; type IV pilus assembly PilZ 3438981 7117596 Mchl_3257 Methylobacterium extorquens CM4 type IV pilus assembly PilZ YP_002422022.1 3438391 R 440085 CDS YP_002422023.1 218531207 7117597 3439403..3439621 1 NC_011757.1 PFAM: SlyX family protein; KEGG: mex:Mext_3034 SlyX family protein; SlyX family protein 3439621 7117597 Mchl_3258 Methylobacterium extorquens CM4 SlyX family protein YP_002422023.1 3439403 D 440085 CDS YP_002422024.1 218531208 7117598 3439657..3439965 1 NC_011757.1 KEGG: mex:Mext_3035 hypothetical protein; hypothetical protein 3439965 7117598 Mchl_3259 Methylobacterium extorquens CM4 hypothetical protein YP_002422024.1 3439657 D 440085 CDS YP_002422025.1 218531209 7117599 complement(3439987..3440406) 1 NC_011757.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: mex:Mext_3036 RNA polymerase-binding protein DksA; TraR/DksA family transcriptional regulator 3440406 7117599 Mchl_3260 Methylobacterium extorquens CM4 TraR/DksA family transcriptional regulator YP_002422025.1 3439987 R 440085 CDS YP_002422026.1 218531210 7117600 complement(3440660..3441679) 1 NC_011757.1 KEGG: mex:Mext_3037 hypothetical protein; hypothetical protein 3441679 7117600 Mchl_3261 Methylobacterium extorquens CM4 hypothetical protein YP_002422026.1 3440660 R 440085 CDS YP_002422027.1 218531211 7117601 complement(3441681..3443054) 1 NC_011757.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: mex:Mext_3038 membrane bound O-acyl transferase MBOAT family protein; membrane bound O-acyl transferase MBOAT family protein 3443054 7117601 Mchl_3262 Methylobacterium extorquens CM4 membrane bound O-acyl transferase MBOAT family protein YP_002422027.1 3441681 R 440085 CDS YP_002422028.1 218531212 7117602 3443426..3443722 1 NC_011757.1 KEGG: mex:Mext_3039 hypothetical protein; hypothetical protein 3443722 7117602 Mchl_3263 Methylobacterium extorquens CM4 hypothetical protein YP_002422028.1 3443426 D 440085 CDS YP_002422029.1 218531213 7117603 complement(3443767..3444207) 1 NC_011757.1 KEGG: mex:Mext_3040 hypothetical protein; hypothetical protein 3444207 7117603 Mchl_3264 Methylobacterium extorquens CM4 hypothetical protein YP_002422029.1 3443767 R 440085 CDS YP_002422030.1 218531214 7117604 3444461..3445603 1 NC_011757.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 3445603 flgI 7117604 flgI Methylobacterium extorquens CM4 flagellar basal body P-ring protein YP_002422030.1 3444461 D 440085 CDS YP_002422031.1 218531215 7117605 3445630..3445989 1 NC_011757.1 KEGG: mex:Mext_3042 hypothetical protein; hypothetical protein 3445989 7117605 Mchl_3266 Methylobacterium extorquens CM4 hypothetical protein YP_002422031.1 3445630 D 440085 CDS YP_002422032.1 218531216 7117606 3445979..3446458 1 NC_011757.1 KEGG: mex:Mext_3043 hypothetical protein; hypothetical protein 3446458 7117606 Mchl_3267 Methylobacterium extorquens CM4 hypothetical protein YP_002422032.1 3445979 D 440085 CDS YP_002422033.1 218531217 7117607 3446797..3446973 1 NC_011757.1 KEGG: mex:Mext_3044 hypothetical protein; hypothetical protein 3446973 7117607 Mchl_3268 Methylobacterium extorquens CM4 hypothetical protein YP_002422033.1 3446797 D 440085 CDS YP_002422034.1 218531218 7117608 complement(3447202..3447954) 1 NC_011757.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 3447954 flgH 7117608 flgH Methylobacterium extorquens CM4 flagellar basal body L-ring protein YP_002422034.1 3447202 R 440085 CDS YP_002422035.1 218531219 7117609 complement(3448011..3449057) 1 NC_011757.1 TIGRFAM: flagella basal body P-ring formation protein FlgA; PFAM: SAF domain protein; KEGG: mex:Mext_3046 flagella basal body P-ring formation protein FlgA; flagella basal body P-ring formation protein FlgA 3449057 7117609 Mchl_3270 Methylobacterium extorquens CM4 flagella basal body P-ring formation protein FlgA YP_002422035.1 3448011 R 440085 CDS YP_002422036.1 218531220 7117610 complement(3449072..3449863) 1 NC_011757.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: mex:Mext_3047 flagellar basal-body rod protein FlgG; flagellar basal-body rod protein FlgG 3449863 7117610 Mchl_3271 Methylobacterium extorquens CM4 flagellar basal-body rod protein FlgG YP_002422036.1 3449072 R 440085 CDS YP_002422037.1 218531221 7117611 complement(3449890..3450630) 1 NC_011757.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagellum; flagellar basal body rod protein FlgF 3450630 flgF 7117611 flgF Methylobacterium extorquens CM4 flagellar basal body rod protein FlgF YP_002422037.1 3449890 R 440085 CDS YP_002422038.1 218531222 7117612 3450904..3451422 1 NC_011757.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 3451422 fliL 7117612 fliL Methylobacterium extorquens CM4 flagellar basal body-associated protein FliL YP_002422038.1 3450904 D 440085 CDS YP_002422039.1 218531223 7117613 3451502..3452722 1 NC_011757.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar motor switch protein FliM 3452722 fliM 7117613 fliM Methylobacterium extorquens CM4 flagellar motor switch protein FliM YP_002422039.1 3451502 D 440085 CDS YP_002422040.1 218531224 7117614 3452736..3453215 1 NC_011757.1 KEGG: mex:Mext_3051 hypothetical protein; hypothetical protein 3453215 7117614 Mchl_3275 Methylobacterium extorquens CM4 hypothetical protein YP_002422040.1 3452736 D 440085 CDS YP_002422041.1 218531225 7117615 3453212..3454009 1 NC_011757.1 KEGG: mex:Mext_3052 hypothetical protein; hypothetical protein 3454009 7117615 Mchl_3276 Methylobacterium extorquens CM4 hypothetical protein YP_002422041.1 3453212 D 440085 CDS YP_002422042.1 218531226 7117616 complement(3454013..3454507) 1 NC_011757.1 PFAM: glutathione peroxidase; KEGG: mex:Mext_3053 peroxiredoxin; peroxiredoxin 3454507 7117616 Mchl_3277 Methylobacterium extorquens CM4 peroxiredoxin YP_002422042.1 3454013 R 440085 CDS YP_002422043.1 218531227 7116547 3454838..3455527 1 NC_011757.1 PFAM: invasion associated locus B family protein; KEGG: mex:Mext_3054 invasion associated locus B family protein; invasion associated locus B family protein 3455527 7116547 Mchl_3278 Methylobacterium extorquens CM4 invasion associated locus B family protein YP_002422043.1 3454838 D 440085 CDS YP_002422044.1 218531228 7117046 3455574..3456815 1 NC_011757.1 TIGRFAM: lytic murein transglycosylase; PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_3055 lytic murein transglycosylase; lytic murein transglycosylase 3456815 7117046 Mchl_3279 Methylobacterium extorquens CM4 lytic murein transglycosylase YP_002422044.1 3455574 D 440085 CDS YP_002422045.1 218531229 7117047 3456822..3457406 1 NC_011757.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mex:Mext_3056 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 3457406 7117047 Mchl_3280 Methylobacterium extorquens CM4 NAD(P)H dehydrogenase (quinone) YP_002422045.1 3456822 D 440085 CDS YP_002422046.1 218531230 7117048 complement(3457446..3458330) 1 NC_011757.1 PFAM: elongation factor G domain protein; elongation factor G domain IV; KEGG: mex:Mext_3057 elongation factor G domain-containing protein; elongation factor G domain IV 3458330 7117048 Mchl_3281 Methylobacterium extorquens CM4 elongation factor G domain IV YP_002422046.1 3457446 R 440085 CDS YP_002422047.1 218531231 7117049 complement(3458559..3458954) 1 NC_011757.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: mex:Mext_3058 glutathione-dependent formaldehyde-activating GFA; glutathione-dependent formaldehyde-activating protein 3458954 7117049 Mchl_3282 Methylobacterium extorquens CM4 glutathione-dependent formaldehyde-activating protein YP_002422047.1 3458559 R 440085 CDS YP_002422048.1 218531232 7117050 complement(3459147..3460490) 1 NC_011757.1 PFAM: sodium:dicarboxylate symporter; KEGG: mex:Mext_3059 sodium:dicarboxylate symporter; sodium:dicarboxylate symporter 3460490 7117050 Mchl_3283 Methylobacterium extorquens CM4 sodium:dicarboxylate symporter YP_002422048.1 3459147 R 440085 CDS YP_002422049.1 218531233 7117051 3460802..3462679 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_3060 ATPase domain-containing protein; histidine kinase 3462679 7117051 Mchl_3284 Methylobacterium extorquens CM4 histidine kinase YP_002422049.1 3460802 D 440085 CDS YP_002422050.1 218531234 7117052 3462676..3464028 1 NC_011757.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: mex:Mext_3061 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 3464028 7117052 Mchl_3285 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002422050.1 3462676 D 440085 CDS YP_002422051.1 218531235 7117053 complement(3464042..3465100) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3062 diguanylate cyclase; diguanylate cyclase 3465100 7117053 Mchl_3286 Methylobacterium extorquens CM4 diguanylate cyclase YP_002422051.1 3464042 R 440085 CDS YP_002422052.1 218531236 7117054 complement(3465355..3468366) 1 NC_011757.1 KEGG: mex:Mext_3063 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase 3468366 7117054 Mchl_3287 Methylobacterium extorquens CM4 PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase YP_002422052.1 3465355 R 440085 CDS YP_002422053.1 218531237 7117055 complement(3468785..3470257) 1 NC_011757.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB/Yqey domain protein; GatB region; GatB central domain protein; KEGG: mex:Mext_3064 glutamyl-tRNA(Gln) amidotransferase subunit beta; glutamyl-tRNA(Gln) amidotransferase subunit beta 3470257 7117055 Mchl_3288 Methylobacterium extorquens CM4 glutamyl-tRNA(Gln) amidotransferase subunit beta YP_002422053.1 3468785 R 440085 CDS YP_002422054.1 218531238 7117056 complement(3470372..3470575) 1 NC_011757.1 KEGG: mpo:Mpop_3263 hypothetical protein; hypothetical protein 3470575 7117056 Mchl_3289 Methylobacterium extorquens CM4 hypothetical protein YP_002422054.1 3470372 R 440085 CDS YP_002422055.1 218531239 7117057 complement(3470572..3471459) 1 NC_011757.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mex:Mext_3065 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 3471459 7117057 Mchl_3290 Methylobacterium extorquens CM4 cation diffusion facilitator family transporter YP_002422055.1 3470572 R 440085 CDS YP_002422056.1 218531240 7117058 complement(3471533..3471796) 1 NC_011757.1 KEGG: mex:Mext_3066 hypothetical protein; hypothetical protein 3471796 7117058 Mchl_3291 Methylobacterium extorquens CM4 hypothetical protein YP_002422056.1 3471533 R 440085 CDS YP_002422057.1 218531241 7117059 complement(3471829..3472077) 1 NC_011757.1 KEGG: mex:Mext_3067 hypothetical protein; hypothetical protein 3472077 7117059 Mchl_3292 Methylobacterium extorquens CM4 hypothetical protein YP_002422057.1 3471829 R 440085 CDS YP_002422058.1 218531242 7117060 complement(3472144..3473604) 1 NC_011757.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_3068 monooxygenase FAD-binding; FAD-binding monooxygenase 3473604 7117060 Mchl_3293 Methylobacterium extorquens CM4 FAD-binding monooxygenase YP_002422058.1 3472144 R 440085 CDS YP_002422059.1 218531243 7117061 3473697..3474803 1 NC_011757.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3474803 queA 7117061 queA Methylobacterium extorquens CM4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002422059.1 3473697 D 440085 CDS YP_002422060.1 218531244 7117062 3474800..3475642 1 NC_011757.1 PFAM: DNA polymerase beta domain protein region; KEGG: mex:Mext_3070 hypothetical protein; DNA polymerase beta domain-containing protein 3475642 7117062 Mchl_3295 Methylobacterium extorquens CM4 DNA polymerase beta domain-containing protein YP_002422060.1 3474800 D 440085 CDS YP_002422061.1 218531245 7117063 3475639..3476790 1 NC_011757.1 KEGG: mex:Mext_3071 queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: queuine/other tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 3476790 7117063 Mchl_3296 Methylobacterium extorquens CM4 queuine tRNA-ribosyltransferase YP_002422061.1 3475639 D 440085 CDS YP_002422062.1 218531246 7117064 complement(3476814..3477071) 1 NC_011757.1 KEGG: mex:Mext_3072 hypothetical protein; hypothetical protein 3477071 7117064 Mchl_3297 Methylobacterium extorquens CM4 hypothetical protein YP_002422062.1 3476814 R 440085 CDS YP_002422063.1 218531247 7117065 complement(3477272..3478339) 1 NC_011757.1 KEGG: mex:Mext_3073 hypothetical protein; hypothetical protein 3478339 7117065 Mchl_3298 Methylobacterium extorquens CM4 hypothetical protein YP_002422063.1 3477272 R 440085 CDS YP_002422064.1 218531248 7117067 complement(3478771..3479037) 1 NC_011757.1 KEGG: mpo:Mpop_1338 hypothetical protein; hypothetical protein 3479037 7117067 Mchl_3299 Methylobacterium extorquens CM4 hypothetical protein YP_002422064.1 3478771 R 440085 CDS YP_002422065.1 218531249 7117069 complement(3479551..3480063) 1 NC_011757.1 KEGG: mrd:Mrad2831_5181 transposase of insertion sequence; transposase of insertion sequence 3480063 7117069 Mchl_3301 Methylobacterium extorquens CM4 transposase of insertion sequence YP_002422065.1 3479551 R 440085 CDS YP_002422066.1 218531250 7117071 3481314..3481982 1 NC_011757.1 KEGG: bpa:BPP2679 hypothetical protein; hypothetical protein 3481982 7117071 Mchl_3303 Methylobacterium extorquens CM4 hypothetical protein YP_002422066.1 3481314 D 440085 CDS YP_002422067.1 218531251 7117072 3482023..3484080 1 NC_011757.1 KEGG: xau:Xaut_0987 hypothetical protein; hypothetical protein 3484080 7117072 Mchl_3304 Methylobacterium extorquens CM4 hypothetical protein YP_002422067.1 3482023 D 440085 CDS YP_002422068.1 218531252 7117073 3484080..3484970 1 NC_011757.1 PFAM: OmpA/MotB domain protein; KEGG: xau:Xaut_0988 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 3484970 7117073 Mchl_3305 Methylobacterium extorquens CM4 OmpA/MotB domain-containing protein YP_002422068.1 3484080 D 440085 CDS YP_002422069.1 218531253 7117074 3484967..3486283 1 NC_011757.1 KEGG: xau:Xaut_0989 hypothetical protein; hypothetical protein 3486283 7117074 Mchl_3306 Methylobacterium extorquens CM4 hypothetical protein YP_002422069.1 3484967 D 440085 CDS YP_002422070.1 218531254 7117075 3486283..3489384 1 NC_011757.1 KEGG: lpf:lpl1068 hypothetical protein; PFAM: SNF2-related protein; helicase; SMART: DEAD-like helicases; non-specific serine/threonine protein kinase 3489384 7117075 Mchl_3307 Methylobacterium extorquens CM4 non-specific serine/threonine protein kinase YP_002422070.1 3486283 D 440085 CDS YP_002422071.1 218531255 7117076 3489548..3491719 1 NC_011757.1 PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: rpb:RPB_1590 AAA_5 ATPase; ATPase AAA 3491719 7117076 Mchl_3308 Methylobacterium extorquens CM4 ATPase AAA YP_002422071.1 3489548 D 440085 CDS YP_002422072.1 218531256 7117077 3491716..3492996 1 NC_011757.1 PFAM: IQ calmodulin-binding- domain protein; KEGG: rpb:RPB_1591 hypothetical protein; IQ calmodulin-binding- domain-containing protein 3492996 7117077 Mchl_3309 Methylobacterium extorquens CM4 IQ calmodulin-binding- domain-containing protein YP_002422072.1 3491716 D 440085 CDS YP_002422073.1 218531257 7117078 complement(3493254..3493424) 1 NC_011757.1 hypothetical protein 3493424 7117078 Mchl_3310 Methylobacterium extorquens CM4 hypothetical protein YP_002422073.1 3493254 R 440085 CDS YP_002422074.1 218531258 7117079 complement(3493971..3494942) 1 NC_011757.1 hypothetical protein 3494942 7117079 Mchl_3311 Methylobacterium extorquens CM4 hypothetical protein YP_002422074.1 3493971 R 440085 CDS YP_002422075.1 218531259 7117080 complement(3495023..3496888) 1 NC_011757.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: rle:pRL110096 hypothetical protein; hypothetical protein 3496888 7117080 Mchl_3312 Methylobacterium extorquens CM4 hypothetical protein YP_002422075.1 3495023 R 440085 CDS YP_002422076.1 218531260 7117081 complement(3496913..3498109) 1 NC_011757.1 KEGG: gbe:GbCGDNIH1_1519 hypothetical cytosolic protein; hypothetical protein 3498109 7117081 Mchl_3313 Methylobacterium extorquens CM4 hypothetical protein YP_002422076.1 3496913 R 440085 CDS YP_002422077.1 218531261 7117082 complement(3498102..3500177) 1 NC_011757.1 KEGG: nar:Saro_0264 hypothetical protein; hypothetical protein 3500177 7117082 Mchl_3314 Methylobacterium extorquens CM4 hypothetical protein YP_002422077.1 3498102 R 440085 CDS YP_002422078.1 218531262 7117083 complement(3500179..3502968) 1 NC_011757.1 KEGG: pap:PSPA7_5334 type II restriction enzyme, methylase subunit; type II restriction enzyme, methylase subunit 3502968 7117083 Mchl_3315 Methylobacterium extorquens CM4 type II restriction enzyme, methylase subunit YP_002422078.1 3500179 R 440085 CDS YP_002422079.1 218531263 7117084 complement(3507164..3507472) 1 NC_011757.1 hypothetical protein 3507472 7117084 Mchl_3316 Methylobacterium extorquens CM4 hypothetical protein YP_002422079.1 3507164 R 440085 CDS YP_002422080.1 218531264 7117085 complement(3507469..3507672) 1 NC_011757.1 hypothetical protein 3507672 7117085 Mchl_3317 Methylobacterium extorquens CM4 hypothetical protein YP_002422080.1 3507469 R 440085 CDS YP_002422081.1 218531265 7117086 complement(3507740..3508117) 1 NC_011757.1 hypothetical protein 3508117 7117086 Mchl_3318 Methylobacterium extorquens CM4 hypothetical protein YP_002422081.1 3507740 R 440085 CDS YP_002422082.1 218531266 7117087 complement(3508278..3508781) 1 NC_011757.1 KEGG: mpo:Mpop_1362 hypothetical protein; hypothetical protein 3508781 7117087 Mchl_3319 Methylobacterium extorquens CM4 hypothetical protein YP_002422082.1 3508278 R 440085 CDS YP_002422083.1 218531267 7117088 complement(3508778..3509029) 1 NC_011757.1 KEGG: mpo:Mpop_1363 hypothetical protein; hypothetical protein 3509029 7117088 Mchl_3320 Methylobacterium extorquens CM4 hypothetical protein YP_002422083.1 3508778 R 440085 CDS YP_002422084.1 218531268 7117089 complement(3509026..3509271) 1 NC_011757.1 KEGG: mpo:Mpop_1364 hypothetical protein; hypothetical protein 3509271 7117089 Mchl_3321 Methylobacterium extorquens CM4 hypothetical protein YP_002422084.1 3509026 R 440085 CDS YP_002422085.1 218531269 7117090 complement(3509282..3509932) 1 NC_011757.1 KEGG: mpo:Mpop_1365 hypothetical protein; hypothetical protein 3509932 7117090 Mchl_3322 Methylobacterium extorquens CM4 hypothetical protein YP_002422085.1 3509282 R 440085 CDS YP_002422086.1 218531270 7117091 3510069..3511190 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_3077 integrase family protein; integrase family protein 3511190 7117091 Mchl_3323 Methylobacterium extorquens CM4 integrase family protein YP_002422086.1 3510069 D 440085 CDS YP_002422087.1 218531271 7117092 3511474..3511611 1 NC_011757.1 hypothetical protein 3511611 7117092 Mchl_3324 Methylobacterium extorquens CM4 hypothetical protein YP_002422087.1 3511474 D 440085 CDS YP_002422088.1 218531272 7117093 3511622..3511837 1 NC_011757.1 KEGG: mex:Mext_0360 hypothetical protein; hypothetical protein 3511837 7117093 Mchl_3325 Methylobacterium extorquens CM4 hypothetical protein YP_002422088.1 3511622 D 440085 CDS YP_002422089.1 218531273 7117094 3511851..3512114 1 NC_011757.1 KEGG: mex:Mext_0153 hypothetical protein; hypothetical protein 3512114 7117094 Mchl_3326 Methylobacterium extorquens CM4 hypothetical protein YP_002422089.1 3511851 D 440085 CDS YP_002422090.1 218531274 7117095 3512258..3512416 1 NC_011757.1 hypothetical protein 3512416 7117095 Mchl_3327 Methylobacterium extorquens CM4 hypothetical protein YP_002422090.1 3512258 D 440085 CDS YP_002422091.1 218531275 7117096 complement(3512835..3513536) 1 NC_011757.1 hypothetical protein 3513536 7117096 Mchl_3328 Methylobacterium extorquens CM4 hypothetical protein YP_002422091.1 3512835 R 440085 CDS YP_002422092.1 218531276 7117097 complement(3514527..3514991) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mpo:Mpop_2952 MucR family transcriptional regulator; MucR family transcriptional regulator 3514991 7117097 Mchl_3329 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002422092.1 3514527 R 440085 CDS YP_002422093.1 218531277 7117098 complement(3515292..3515750) 1 NC_011757.1 hypothetical protein 3515750 7117098 Mchl_3330 Methylobacterium extorquens CM4 hypothetical protein YP_002422093.1 3515292 R 440085 CDS YP_002422094.1 218531278 7117099 complement(3515747..3516208) 1 NC_011757.1 hypothetical protein 3516208 7117099 Mchl_3331 Methylobacterium extorquens CM4 hypothetical protein YP_002422094.1 3515747 R 440085 CDS YP_002422095.1 218531279 7117100 complement(3516233..3516724) 1 NC_011757.1 KEGG: mex:Mext_0353 hypothetical protein; hypothetical protein 3516724 7117100 Mchl_3332 Methylobacterium extorquens CM4 hypothetical protein YP_002422095.1 3516233 R 440085 CDS YP_002422096.1 218531280 7117101 3516978..3519296 1 NC_011757.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; KEGG: ccr:CC_0740 sensory box/GGDEF family protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 3519296 7117101 Mchl_3333 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_002422096.1 3516978 D 440085 CDS YP_002422097.1 218531281 7117103 3521250..3524078 1 NC_011757.1 KEGG: met:M446_1053 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 3524078 7117103 Mchl_3335 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002422097.1 3521250 D 440085 CDS YP_002422098.1 218531282 7117104 3524427..3527624 1 NC_011757.1 KEGG: mex:Mext_0802 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 3527624 7117104 Mchl_3336 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002422098.1 3524427 D 440085 CDS YP_002422099.1 218531283 7117107 3529346..3530224 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; KEGG: mrd:Mrad2831_5229 anti-sigma-factor antagonist; anti-sigma-factor antagonist 3530224 7117107 Mchl_3339 Methylobacterium extorquens CM4 anti-sigma-factor antagonist YP_002422099.1 3529346 D 440085 CDS YP_002422100.1 218531284 7117108 3530229..3530630 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; KEGG: mrd:Mrad2831_5230 anti-sigma-factor antagonist; anti-sigma-factor antagonist 3530630 7117108 Mchl_3340 Methylobacterium extorquens CM4 anti-sigma-factor antagonist YP_002422100.1 3530229 D 440085 CDS YP_002422101.1 218531285 7117109 3530611..3531015 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mrd:Mrad2831_5231 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 3531015 7117109 Mchl_3341 Methylobacterium extorquens CM4 anti-sigma regulatory factor, serine/threonine protein kinase YP_002422101.1 3530611 D 440085 CDS YP_002422102.1 218531286 7117110 3531018..3532019 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: mrd:Mrad2831_5232 anti-sigma regulatory factor, serine/threonine protein kinase; anti-sigma regulatory factor, serine/threonine protein kinase 3532019 7117110 Mchl_3342 Methylobacterium extorquens CM4 anti-sigma regulatory factor, serine/threonine protein kinase YP_002422102.1 3531018 D 440085 CDS YP_002422103.1 218531287 7117111 3532016..3533914 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_5233 histidine kinase; histidine kinase 3533914 7117111 Mchl_3343 Methylobacterium extorquens CM4 histidine kinase YP_002422103.1 3532016 D 440085 CDS YP_002422104.1 218531288 7117112 complement(3533997..3535007) 1 NC_011757.1 KEGG: mex:Mext_1888 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 3535007 7117112 Mchl_3344 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002422104.1 3533997 R 440085 CDS YP_002422105.1 218531289 7117115 3537280..3538503 1 NC_011757.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 3538503 nhaA 7117115 nhaA Methylobacterium extorquens CM4 pH-dependent sodium/proton antiporter YP_002422105.1 3537280 D 440085 CDS YP_002422106.1 218531290 7117116 3538500..3539789 1 NC_011757.1 PFAM: formate C-acetyltransferase glycine radical; KEGG: mpo:Mpop_3748 hypothetical protein; formate C-acetyltransferase glycine radical 3539789 7117116 Mchl_3348 Methylobacterium extorquens CM4 formate C-acetyltransferase glycine radical YP_002422106.1 3538500 D 440085 CDS YP_002422107.1 218531291 7117117 3539921..3540358 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: scl:sce5286 methyltransferase; type 11 methyltransferase 3540358 7117117 Mchl_3349 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002422107.1 3539921 D 440085 CDS YP_002422108.1 218531292 7117118 complement(3540425..3540670) 1 NC_011757.1 hypothetical protein 3540670 7117118 Mchl_3350 Methylobacterium extorquens CM4 hypothetical protein YP_002422108.1 3540425 R 440085 CDS YP_002422109.1 218531293 7117119 complement(3540992..3542254) 1 NC_011757.1 PFAM: sodium/hydrogen exchanger; KEGG: mrd:Mrad2831_6040 sodium/hydrogen exchanger; sodium/hydrogen exchanger 3542254 7117119 Mchl_3351 Methylobacterium extorquens CM4 sodium/hydrogen exchanger YP_002422109.1 3540992 R 440085 CDS YP_002422110.1 218531294 7117120 3543038..3543559 1 NC_011757.1 PFAM: protein of unknown function DUF421; KEGG: pla:Plav_3285 membrane protein-like protein; hypothetical protein 3543559 7117120 Mchl_3352 Methylobacterium extorquens CM4 hypothetical protein YP_002422110.1 3543038 D 440085 CDS YP_002422111.1 218531295 7117123 complement(3544214..3545488) 1 NC_011757.1 PFAM: sodium/hydrogen exchanger; KEGG: rru:Rru_A1350 sodium/hydrogen exchanger; sodium/hydrogen exchanger 3545488 7117123 Mchl_3355 Methylobacterium extorquens CM4 sodium/hydrogen exchanger YP_002422111.1 3544214 R 440085 CDS YP_002422112.1 218531296 7117125 complement(3546034..3546663) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_0119 integrase family protein; integrase family protein 3546663 7117125 Mchl_3357 Methylobacterium extorquens CM4 integrase family protein YP_002422112.1 3546034 R 440085 CDS YP_002422113.1 218531297 7115841 complement(3547074..3548102) 1 NC_011757.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr5983 transposase; transposase IS116/IS110/IS902 family protein 3548102 7115841 Mchl_3359 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002422113.1 3547074 R 440085 CDS YP_002422114.1 218531298 7116006 3548957..3550243 1 NC_011757.1 KEGG: gbe:GbCGDNIH1_1776 hypothetical membrane associated protein; hypothetical protein 3550243 7116006 Mchl_3360 Methylobacterium extorquens CM4 hypothetical protein YP_002422114.1 3548957 D 440085 CDS YP_002422115.1 218531299 7116008 complement(3550813..3551118) 1 NC_011757.1 KEGG: nwi:Nwi_3091 hypothetical protein; hypothetical protein 3551118 7116008 Mchl_3362 Methylobacterium extorquens CM4 hypothetical protein YP_002422115.1 3550813 R 440085 CDS YP_002422116.1 218531300 7116009 complement(3551204..3551680) 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; KEGG: mex:Mext_0113 PAS sensor protein; PAS sensor protein 3551680 7116009 Mchl_3363 Methylobacterium extorquens CM4 PAS sensor protein YP_002422116.1 3551204 R 440085 CDS YP_002422117.1 218531301 7116010 3551902..3552354 1 NC_011757.1 PFAM: BLUF domain protein; KEGG: mex:Mext_0114 BLUF domain-containing protein; BLUF domain-containing protein 3552354 7116010 Mchl_3364 Methylobacterium extorquens CM4 BLUF domain-containing protein YP_002422117.1 3551902 D 440085 CDS YP_002422118.1 218531302 7116012 complement(3552751..3554493) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: met:M446_1292 integral membrane sensor hybrid histidine kinase; histidine kinase 3554493 7116012 Mchl_3366 Methylobacterium extorquens CM4 histidine kinase YP_002422118.1 3552751 R 440085 CDS YP_002422119.1 218531303 7116014 3556102..3557256 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: aav:Aave_4017 alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase GroES domain-containing protein 3557256 7116014 Mchl_3368 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES domain-containing protein YP_002422119.1 3556102 D 440085 CDS YP_002422120.1 218531304 7116015 3557268..3557789 1 NC_011757.1 KEGG: aav:Aave_4018 hypothetical protein; hypothetical protein 3557789 7116015 Mchl_3369 Methylobacterium extorquens CM4 hypothetical protein YP_002422120.1 3557268 D 440085 CDS YP_002422121.1 218531305 7116016 3559336..3559596 1 NC_011757.1 hypothetical protein 3559596 7116016 Mchl_3370 Methylobacterium extorquens CM4 hypothetical protein YP_002422121.1 3559336 D 440085 CDS YP_002422122.1 218531306 7116017 complement(3561258..3561569) 1 NC_011757.1 KEGG: mex:Mext_0064 hypothetical protein; hypothetical protein 3561569 7116017 Mchl_3371 Methylobacterium extorquens CM4 hypothetical protein YP_002422122.1 3561258 R 440085 CDS YP_002422123.1 218531307 7116018 complement(3561622..3562368) 1 NC_011757.1 KEGG: mex:Mext_0063 hypothetical protein; hypothetical protein 3562368 7116018 Mchl_3372 Methylobacterium extorquens CM4 hypothetical protein YP_002422123.1 3561622 R 440085 CDS YP_002422124.1 218531308 7116019 complement(3562398..3562652) 1 NC_011757.1 KEGG: mex:Mext_0062 isochorismatase hydrolase; hypothetical protein 3562652 7116019 Mchl_3373 Methylobacterium extorquens CM4 hypothetical protein YP_002422124.1 3562398 R 440085 CDS YP_002422125.1 218531309 7116020 3564285..3565055 1 NC_011757.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: mrd:Mrad2831_2421 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 3565055 7116020 Mchl_3374 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422125.1 3564285 D 440085 CDS YP_002422126.1 218531310 7116021 complement(3565037..3565234) 1 NC_011757.1 KEGG: mex:Mext_0076 hypothetical protein; hypothetical protein 3565234 7116021 Mchl_3375 Methylobacterium extorquens CM4 hypothetical protein YP_002422126.1 3565037 R 440085 CDS YP_002422127.1 218531311 7116022 complement(3565273..3565983) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_0788 cyclic nucleotide-binding; cyclic nucleotide-binding protein 3565983 7116022 Mchl_3376 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002422127.1 3565273 R 440085 CDS YP_002422128.1 218531312 7116023 3566301..3566522 1 NC_011757.1 KEGG: mex:Mext_0787 hypothetical protein; hypothetical protein 3566522 7116023 Mchl_3377 Methylobacterium extorquens CM4 hypothetical protein YP_002422128.1 3566301 D 440085 CDS YP_002422129.1 218531313 7116024 complement(3566644..3566859) 1 NC_011757.1 KEGG: mex:Mext_0785 hypothetical protein; hypothetical protein 3566859 7116024 Mchl_3378 Methylobacterium extorquens CM4 hypothetical protein YP_002422129.1 3566644 R 440085 CDS YP_002422130.1 218531314 7116027 3568293..3569129 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mex:Mext_3531 integrase catalytic region; integrase catalytic subunit 3569129 7116027 Mchl_3381 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002422130.1 3568293 D 440085 CDS YP_002422131.1 218531315 7116028 complement(3569997..3570284) 1 NC_011757.1 KEGG: mex:Mext_4708 hypothetical protein; hypothetical protein 3570284 7116028 Mchl_3382 Methylobacterium extorquens CM4 hypothetical protein YP_002422131.1 3569997 R 440085 CDS YP_002422132.1 218531316 7116029 complement(3570446..3570805) 1 NC_011757.1 KEGG: mpo:Mpop_3761 hypothetical protein; hypothetical protein 3570805 7116029 Mchl_3383 Methylobacterium extorquens CM4 hypothetical protein YP_002422132.1 3570446 R 440085 CDS YP_002422133.1 218531317 7116030 complement(3571558..3571659) 1 NC_011757.1 KEGG: mex:Mext_0782 hypothetical protein; hypothetical protein 3571659 7116030 Mchl_3384 Methylobacterium extorquens CM4 hypothetical protein YP_002422133.1 3571558 R 440085 CDS YP_002422134.1 218531318 7116031 complement(3571656..3572810) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: response regulator receiver; KEGG: mex:Mext_0783 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 3572810 7116031 Mchl_3385 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422134.1 3571656 R 440085 CDS YP_002422135.1 218531319 7116032 3573079..3573792 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_0075 hypothetical protein; cyclic nucleotide-binding protein 3573792 7116032 Mchl_3386 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002422135.1 3573079 D 440085 CDS YP_002422136.1 218531320 7116033 3573792..3574052 1 NC_011757.1 KEGG: mex:Mext_0785 hypothetical protein; hypothetical protein 3574052 7116033 Mchl_3387 Methylobacterium extorquens CM4 hypothetical protein YP_002422136.1 3573792 D 440085 CDS YP_002422137.1 218531321 7116035 complement(3574665..3575411) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mrd:Mrad2831_2433 Crp/FNR family transcriptional regulator; Crp/Fnr family transcriptional regulator 3575411 7116035 Mchl_3389 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422137.1 3574665 R 440085 CDS YP_002422138.1 218531322 7116036 3575989..3576348 1 NC_011757.1 hypothetical protein 3576348 7116036 Mchl_3390 Methylobacterium extorquens CM4 hypothetical protein YP_002422138.1 3575989 D 440085 CDS YP_002422139.1 218531323 7116037 complement(3576603..3577322) 1 NC_011757.1 hypothetical protein 3577322 7116037 Mchl_3391 Methylobacterium extorquens CM4 hypothetical protein YP_002422139.1 3576603 R 440085 CDS YP_002422140.1 218531324 7116038 complement(3577306..3577602) 1 NC_011757.1 hypothetical protein 3577602 7116038 Mchl_3392 Methylobacterium extorquens CM4 hypothetical protein YP_002422140.1 3577306 R 440085 CDS YP_002422141.1 218531325 7116039 complement(3577599..3577940) 1 NC_011757.1 hypothetical protein 3577940 7116039 Mchl_3393 Methylobacterium extorquens CM4 hypothetical protein YP_002422141.1 3577599 R 440085 CDS YP_002422142.1 218531326 7116040 complement(3578088..3578342) 1 NC_011757.1 KEGG: met:M446_6723 prophage CP4-57 regulatory; hypothetical protein 3578342 7116040 Mchl_3394 Methylobacterium extorquens CM4 hypothetical protein YP_002422142.1 3578088 R 440085 CDS YP_002422143.1 218531327 7116041 complement(3578396..3579151) 1 NC_011757.1 hypothetical protein 3579151 7116041 Mchl_3395 Methylobacterium extorquens CM4 hypothetical protein YP_002422143.1 3578396 R 440085 CDS YP_002422144.1 218531328 7116042 complement(3579148..3580392) 1 NC_011757.1 PFAM: integrase family protein; KEGG: rsq:Rsph17025_0112 phage integrase family protein; integrase family protein 3580392 7116042 Mchl_3396 Methylobacterium extorquens CM4 integrase family protein YP_002422144.1 3579148 R 440085 CDS YP_002422145.1 218531329 7116044 3580914..3582248 1 NC_011757.1 PFAM: tyrosine protein kinase; leucine-rich repeat protein; SMART: serine/threonine protein kinase; leucine-rich repeat-containing protein typical subtype; KEGG: mex:Mext_3080 serine/threonine protein kinase; serine/threonine protein kinase 3582248 7116044 Mchl_3397 Methylobacterium extorquens CM4 serine/threonine protein kinase YP_002422145.1 3580914 D 440085 CDS YP_002422146.1 218531330 7116045 3582348..3583886 1 NC_011757.1 PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: mex:Mext_3081 CHAD domain-containing protein; CHAD domain-containing protein 3583886 7116045 Mchl_3398 Methylobacterium extorquens CM4 CHAD domain-containing protein YP_002422146.1 3582348 D 440085 CDS YP_002422147.1 218531331 7116046 3584009..3584515 1 NC_011757.1 PFAM: adenylate cyclase; KEGG: mex:Mext_3082 adenylate cyclase; adenylate cyclase 3584515 7116046 Mchl_3399 Methylobacterium extorquens CM4 adenylate cyclase YP_002422147.1 3584009 D 440085 CDS YP_002422148.1 218531332 7116047 complement(3584525..3585406) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mrd:Mrad2831_2093 ECF subfamily RNA polymerase sigma-24 factor; ECF subfamily RNA polymerase sigma-24 subunit 3585406 7116047 Mchl_3400 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002422148.1 3584525 R 440085 CDS YP_002422149.1 218531333 7116048 complement(3585396..3585860) 1 NC_011757.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: bbr:BB3301 hypothetical protein; alkylhydroperoxidase-like protein 3585860 7116048 Mchl_3401 Methylobacterium extorquens CM4 alkylhydroperoxidase-like protein YP_002422149.1 3585396 R 440085 CDS YP_002422150.1 218531334 7116049 complement(3585894..3586328) 1 NC_011757.1 PFAM: cupin; KEGG: bpt:Bpet3859 Nectarin 1 precursor; cupin 3586328 7116049 Mchl_3402 Methylobacterium extorquens CM4 cupin YP_002422150.1 3585894 R 440085 CDS YP_002422151.1 218531335 7116050 3586523..3588250 1 NC_011757.1 PFAM: ferredoxin; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mex:Mext_3083 adenylyl cyclase class-3/4/guanylyl cyclase; adenylate/guanylate cyclase 3588250 7116050 Mchl_3403 Methylobacterium extorquens CM4 adenylate/guanylate cyclase YP_002422151.1 3586523 D 440085 CDS YP_002422152.1 218531336 7116051 complement(3588259..3589080) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3084 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 3589080 7116051 Mchl_3404 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422152.1 3588259 R 440085 CDS YP_002422153.1 218531337 7116052 complement(3589149..3590336) 1 NC_011757.1 PFAM: major royal jelly protein; KEGG: mpo:Mpop_3279 hypothetical protein; hypothetical protein 3590336 7116052 Mchl_3405 Methylobacterium extorquens CM4 hypothetical protein YP_002422153.1 3589149 R 440085 CDS YP_002422154.1 218531338 7116053 complement(3590427..3591521) 1 NC_011757.1 KEGG: mex:Mext_3086 catalase; catalase 3591521 7116053 Mchl_3406 Methylobacterium extorquens CM4 catalase YP_002422154.1 3590427 R 440085 CDS YP_002422155.1 218531339 7116054 3591723..3591965 1 NC_011757.1 KEGG: mpo:Mpop_3280 hypothetical protein; hypothetical protein 3591965 7116054 Mchl_3407 Methylobacterium extorquens CM4 hypothetical protein YP_002422155.1 3591723 D 440085 CDS YP_002422156.1 218531340 7116055 complement(3592045..3594177) 1 NC_011757.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 3594177 hppA 7116055 hppA Methylobacterium extorquens CM4 membrane-bound proton-translocating pyrophosphatase YP_002422156.1 3592045 R 440085 CDS YP_002422157.1 218531341 7116056 complement(3595005..3595352) 1 NC_011757.1 KEGG: mex:Mext_3089 hypothetical protein; hypothetical protein 3595352 7116056 Mchl_3409 Methylobacterium extorquens CM4 hypothetical protein YP_002422157.1 3595005 R 440085 CDS YP_002422158.1 218531342 7116057 complement(3595565..3595780) 1 NC_011757.1 KEGG: mex:Mext_3090 hypothetical protein; hypothetical protein 3595780 7116057 Mchl_3410 Methylobacterium extorquens CM4 hypothetical protein YP_002422158.1 3595565 R 440085 CDS YP_002422159.1 218531343 7116058 complement(3595998..3597218) 1 NC_011757.1 PFAM: aminotransferase class I and II; KEGG: mex:Mext_3091 aminotransferase; aminotransferase 3597218 7116058 Mchl_3411 Methylobacterium extorquens CM4 aminotransferase YP_002422159.1 3595998 R 440085 CDS YP_002422160.1 218531344 7116059 complement(3597364..3597729) 1 NC_011757.1 KEGG: mex:Mext_3092 hypothetical protein; hypothetical protein 3597729 7116059 Mchl_3412 Methylobacterium extorquens CM4 hypothetical protein YP_002422160.1 3597364 R 440085 CDS YP_002422161.1 218531345 7116060 3597857..3599674 1 NC_011757.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; poly-beta-hydroxybutyrate polymerase domain protein; KEGG: mex:Mext_3093 poly(R)-hydroxyalkanoic acid synthase, class I; poly(R)-hydroxyalkanoic acid synthase, class I 3599674 7116060 Mchl_3413 Methylobacterium extorquens CM4 poly(R)-hydroxyalkanoic acid synthase, class I YP_002422161.1 3597857 D 440085 CDS YP_002422162.1 218531346 7116061 3599800..3601617 1 NC_011757.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mex:Mext_3094 sodium/hydrogen exchanger; sodium/hydrogen exchanger 3601617 7116061 Mchl_3414 Methylobacterium extorquens CM4 sodium/hydrogen exchanger YP_002422162.1 3599800 D 440085 CDS YP_002422163.1 218531347 7116062 complement(3601630..3602814) 1 NC_011757.1 PFAM: regulatory protein LuxR; KEGG: mex:Mext_3095 regulatory protein LuxR; LuxR family transcriptional regulator 3602814 7116062 Mchl_3415 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002422163.1 3601630 R 440085 CDS YP_002422164.1 218531348 7116063 complement(3603070..3605160) 1 NC_011757.1 KEGG: mex:Mext_3096 glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase subunit beta; glycyl-tRNA synthetase subunit beta 3605160 7116063 Mchl_3416 Methylobacterium extorquens CM4 glycyl-tRNA synthetase subunit beta YP_002422164.1 3603070 R 440085 CDS YP_002422165.1 218531349 7116064 complement(3605316..3607202) 1 NC_011757.1 PFAM: protein of unknown function DUF839; KEGG: mex:Mext_3097 hypothetical protein; hypothetical protein 3607202 7116064 Mchl_3417 Methylobacterium extorquens CM4 hypothetical protein YP_002422165.1 3605316 R 440085 CDS YP_002422166.1 218531350 7116065 complement(3607397..3607840) 1 NC_011757.1 KEGG: mex:Mext_3098 hypothetical protein; hypothetical protein 3607840 7116065 Mchl_3418 Methylobacterium extorquens CM4 hypothetical protein YP_002422166.1 3607397 R 440085 CDS YP_002422167.1 218531351 7116066 complement(3607842..3608780) 1 NC_011757.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3608780 glyQ 7116066 glyQ Methylobacterium extorquens CM4 glycyl-tRNA synthetase subunit alpha YP_002422167.1 3607842 R 440085 CDS YP_002422168.1 218531352 7116067 complement(3608877..3609035) 1 NC_011757.1 KEGG: mex:Mext_3100 hypothetical protein; hypothetical protein 3609035 7116067 Mchl_3420 Methylobacterium extorquens CM4 hypothetical protein YP_002422168.1 3608877 R 440085 CDS YP_002422169.1 218531353 7116068 3609286..3609528 1 NC_011757.1 KEGG: mex:Mext_3101 hypothetical protein; hypothetical protein 3609528 7116068 Mchl_3421 Methylobacterium extorquens CM4 hypothetical protein YP_002422169.1 3609286 D 440085 CDS YP_002422170.1 218531354 7116069 complement(3609541..3610104) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_3102 regulatory protein TetR; TetR family transcriptional regulator 3610104 7116069 Mchl_3422 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002422170.1 3609541 R 440085 CDS YP_002422171.1 218531355 7116070 complement(3610108..3610572) 1 NC_011757.1 PFAM: protein of unknown function DUF1348; KEGG: mex:Mext_3103 hypothetical protein; hypothetical protein 3610572 7116070 Mchl_3423 Methylobacterium extorquens CM4 hypothetical protein YP_002422171.1 3610108 R 440085 CDS YP_002422172.1 218531356 7116071 complement(3610716..3611576) 1 NC_011757.1 PFAM: peptidase S49; KEGG: mex:Mext_3105 peptidase S49; peptidase S49 3611576 7116071 Mchl_3424 Methylobacterium extorquens CM4 peptidase S49 YP_002422172.1 3610716 R 440085 CDS YP_002422173.1 218531357 7116072 complement(3611801..3612553) 1 NC_011757.1 PFAM: methyltransferase small; methyltransferase type 12; KEGG: mex:Mext_3106 methyltransferase small; methyltransferase small 3612553 7116072 Mchl_3425 Methylobacterium extorquens CM4 methyltransferase small YP_002422173.1 3611801 R 440085 CDS YP_002422174.1 218531358 7116073 complement(3612565..3612792) 1 NC_011757.1 KEGG: mex:Mext_3107 hypothetical protein; hypothetical protein 3612792 7116073 Mchl_3426 Methylobacterium extorquens CM4 hypothetical protein YP_002422174.1 3612565 R 440085 CDS YP_002422175.1 218531359 7116074 3612987..3614009 1 NC_011757.1 PFAM: polyprenyl synthetase; KEGG: mex:Mext_3108 polyprenyl synthetase; polyprenyl synthetase 3614009 7116074 Mchl_3427 Methylobacterium extorquens CM4 polyprenyl synthetase YP_002422175.1 3612987 D 440085 CDS YP_002422176.1 218531360 7116075 complement(3614031..3614906) 1 NC_011757.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 3614906 7116075 Mchl_3428 Methylobacterium extorquens CM4 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002422176.1 3614031 R 440085 CDS YP_002422177.1 218531361 7116076 complement(3615040..3616683) 1 NC_011757.1 PFAM: porin; KEGG: mex:Mext_3110 porin; porin 3616683 7116076 Mchl_3429 Methylobacterium extorquens CM4 porin YP_002422177.1 3615040 R 440085 CDS YP_002422178.1 218531362 7116077 complement(3617624..3619525) 1 NC_011757.1 PFAM: hypotheticalprotein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: mex:Mext_3111 hypotheticalprotein; hypothetical protein 3619525 7116077 Mchl_3430 Methylobacterium extorquens CM4 hypothetical protein YP_002422178.1 3617624 R 440085 CDS YP_002422179.1 218531363 7116078 complement(3619652..3619957) 1 NC_011757.1 KEGG: mex:Mext_3112 hypothetical protein; hypothetical protein 3619957 7116078 Mchl_3431 Methylobacterium extorquens CM4 hypothetical protein YP_002422179.1 3619652 R 440085 CDS YP_002422180.1 218531364 7116079 complement(3620029..3620241) 1 NC_011757.1 KEGG: mex:Mext_3113 hypothetical protein; hypothetical protein 3620241 7116079 Mchl_3432 Methylobacterium extorquens CM4 hypothetical protein YP_002422180.1 3620029 R 440085 CDS YP_002422181.1 218531365 7116080 3620648..3620887 1 NC_011757.1 KEGG: mex:Mext_3114 hypothetical protein; hypothetical protein 3620887 7116080 Mchl_3433 Methylobacterium extorquens CM4 hypothetical protein YP_002422181.1 3620648 D 440085 CDS YP_002422182.1 218531366 7116081 3621034..3621357 1 NC_011757.1 KEGG: mex:Mext_3115 hypothetical protein; hypothetical protein 3621357 7116081 Mchl_3434 Methylobacterium extorquens CM4 hypothetical protein YP_002422182.1 3621034 D 440085 CDS YP_002422183.1 218531367 7116082 complement(3621408..3622742) 1 NC_011757.1 KEGG: mex:Mext_3116 Nrd protein; Nrd protein 3622742 7116082 Mchl_3435 Methylobacterium extorquens CM4 Nrd protein YP_002422183.1 3621408 R 440085 CDS YP_002422184.1 218531368 7116083 3622908..3623876 1 NC_011757.1 PFAM: band 7 protein; KEGG: mex:Mext_3117 band 7 protein; band 7 protein 3623876 7116083 Mchl_3436 Methylobacterium extorquens CM4 band 7 protein YP_002422184.1 3622908 D 440085 CDS YP_002422185.1 218531369 7116084 3624087..3625757 1 NC_011757.1 KEGG: mex:Mext_3118 cyclic peptide transporter; TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter; SMART: ATPase AAA; cyclic peptide transporter 3625757 7116084 Mchl_3437 Methylobacterium extorquens CM4 cyclic peptide transporter YP_002422185.1 3624087 D 440085 CDS YP_002422186.1 218531370 7116085 3625863..3626138 1 NC_011757.1 KEGG: mpo:Mpop_3314 hypothetical protein; hypothetical protein 3626138 7116085 Mchl_3438 Methylobacterium extorquens CM4 hypothetical protein YP_002422186.1 3625863 D 440085 CDS YP_002422187.1 218531371 7116086 3626135..3626536 1 NC_011757.1 PFAM: PilT protein domain protein; KEGG: mpo:Mpop_3315 PilT protein domain protein; PilT protein domain-containing protein 3626536 7116086 Mchl_3439 Methylobacterium extorquens CM4 PilT protein domain-containing protein YP_002422187.1 3626135 D 440085 CDS YP_002422188.1 218531372 7114196 complement(3626604..3628661) 1 NC_011757.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3628661 7114196 Mchl_3440 Methylobacterium extorquens CM4 DNA topoisomerase IV subunit B YP_002422188.1 3626604 R 440085 CDS YP_002422189.1 218531373 7114198 3629015..3629206 1 NC_011757.1 KEGG: mex:Mext_3120 hypothetical protein; hypothetical protein 3629206 7114198 Mchl_3441 Methylobacterium extorquens CM4 hypothetical protein YP_002422189.1 3629015 D 440085 CDS YP_002422190.1 218531374 7114199 complement(3629230..3630270) 1 NC_011757.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mex:Mext_3121 threonine aldolase; threonine aldolase 3630270 7114199 Mchl_3442 Methylobacterium extorquens CM4 threonine aldolase YP_002422190.1 3629230 R 440085 CDS YP_002422191.1 218531375 7114200 complement(3630412..3632178) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3122 ABC transporter; ABC transporter 3632178 7114200 Mchl_3443 Methylobacterium extorquens CM4 ABC transporter YP_002422191.1 3630412 R 440085 CDS YP_002422192.1 218531376 7114201 complement(3632384..3633739) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_3123 major facilitator transporter; major facilitator superfamily protein 3633739 7114201 Mchl_3444 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422192.1 3632384 R 440085 CDS YP_002422193.1 218531377 7114202 complement(3633736..3634548) 1 NC_011757.1 PFAM: PRC-barrel domain protein; KEGG: mex:Mext_3124 PRC-barrel domain-containing protein; PRC-barrel domain-containing protein 3634548 7114202 Mchl_3445 Methylobacterium extorquens CM4 PRC-barrel domain-containing protein YP_002422193.1 3633736 R 440085 CDS YP_002422194.1 218531378 7114203 3634762..3635136 1 NC_011757.1 KEGG: mex:Mext_3125 hypothetical protein; hypothetical protein 3635136 7114203 Mchl_3446 Methylobacterium extorquens CM4 hypothetical protein YP_002422194.1 3634762 D 440085 CDS YP_002422195.1 218531379 7114204 complement(3635174..3635614) 1 NC_011757.1 PFAM: PRC-barrel domain protein; KEGG: mex:Mext_3126 PRC-barrel domain-containing protein; PRC-barrel domain-containing protein 3635614 7114204 Mchl_3447 Methylobacterium extorquens CM4 PRC-barrel domain-containing protein YP_002422195.1 3635174 R 440085 CDS YP_002422196.1 218531380 7114205 3635934..3636266 1 NC_011757.1 PFAM: SWIB/MDM2 domain protein; KEGG: mex:Mext_3127 SWIB/MDM2 domain-containing protein; SWIB/MDM2 domain-containing protein 3636266 7114205 Mchl_3448 Methylobacterium extorquens CM4 SWIB/MDM2 domain-containing protein YP_002422196.1 3635934 D 440085 CDS YP_002422197.1 218531381 7114206 complement(3636356..3637147) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3128 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3637147 7114206 Mchl_3449 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422197.1 3636356 R 440085 CDS YP_002422198.1 218531382 7114207 complement(3637230..3638609) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_3129 major facilitator transporter; major facilitator superfamily protein 3638609 7114207 Mchl_3450 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422198.1 3637230 R 440085 CDS YP_002422199.1 218531383 7114208 3638838..3639860 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3130 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 3639860 7114208 Mchl_3451 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422199.1 3638838 D 440085 CDS YP_002422200.1 218531384 7114209 3639942..3640808 1 NC_011757.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mex:Mext_3131 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase 3640808 7114209 Mchl_3452 Methylobacterium extorquens CM4 6-phosphogluconate dehydrogenase YP_002422200.1 3639942 D 440085 CDS YP_002422201.1 218531385 7114210 complement(3640812..3641519) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_3132 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 3641519 7114210 Mchl_3453 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002422201.1 3640812 R 440085 CDS YP_002422202.1 218531386 7114211 3641793..3642008 1 NC_011757.1 KEGG: mpo:Mpop_3330 hypothetical protein; hypothetical protein 3642008 7114211 Mchl_3454 Methylobacterium extorquens CM4 hypothetical protein YP_002422202.1 3641793 D 440085 CDS YP_002422203.1 218531387 7114213 3642165..3642476 1 NC_011757.1 PFAM: ETC complex I subunit conserved region; KEGG: mex:Mext_3134 ETC complex I subunit region; ETC complex I subunit conserved region 3642476 7114213 Mchl_3455 Methylobacterium extorquens CM4 ETC complex I subunit conserved region YP_002422203.1 3642165 D 440085 CDS YP_002422204.1 218531388 7114214 complement(3642542..3643003) 1 NC_011757.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: mex:Mext_3135 CMP/dCMP deaminase zinc-binding; zinc-binding CMP/dCMP deaminase 3643003 7114214 Mchl_3456 Methylobacterium extorquens CM4 zinc-binding CMP/dCMP deaminase YP_002422204.1 3642542 R 440085 CDS YP_002422205.1 218531389 7114215 complement(3643018..3644082) 1 NC_011757.1 KEGG: mex:Mext_3136 radical SAM domain-containing protein; radical SAM domain-containing protein 3644082 7114215 Mchl_3457 Methylobacterium extorquens CM4 radical SAM domain-containing protein YP_002422205.1 3643018 R 440085 CDS YP_002422206.1 218531390 7114216 complement(3644142..3644933) 1 NC_011757.1 KEGG: mex:Mext_3137 hypothetical protein; hypothetical protein 3644933 7114216 Mchl_3458 Methylobacterium extorquens CM4 hypothetical protein YP_002422206.1 3644142 R 440085 CDS YP_002422207.1 218531391 7114217 3645160..3647436 1 NC_011757.1 KEGG: mex:Mext_3138 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; glycogen debranching protein GlgX 3647436 7114217 Mchl_3459 Methylobacterium extorquens CM4 glycogen debranching protein GlgX YP_002422207.1 3645160 D 440085 CDS YP_002422208.1 218531392 7114218 3647436..3647612 1 NC_011757.1 hypothetical protein 3647612 7114218 Mchl_3460 Methylobacterium extorquens CM4 hypothetical protein YP_002422208.1 3647436 D 440085 CDS YP_002422209.1 218531393 7114219 3647609..3649210 1 NC_011757.1 KEGG: mex:Mext_3139 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; histidine kinase 3649210 7114219 Mchl_3461 Methylobacterium extorquens CM4 histidine kinase YP_002422209.1 3647609 D 440085 CDS YP_002422210.1 218531394 7114220 3649237..3649554 1 NC_011757.1 KEGG: mex:Mext_3140 hypothetical protein; hypothetical protein 3649554 7114220 Mchl_3462 Methylobacterium extorquens CM4 hypothetical protein YP_002422210.1 3649237 D 440085 CDS YP_002422211.1 218531395 7114221 complement(3649608..3650822) 1 NC_011757.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 3650822 7114221 Mchl_3463 Methylobacterium extorquens CM4 isocitrate dehydrogenase YP_002422211.1 3649608 R 440085 CDS YP_002422212.1 218531396 7114222 complement(3650967..3651479) 1 NC_011757.1 KEGG: mex:Mext_3142 hypothetical protein; hypothetical protein 3651479 7114222 Mchl_3464 Methylobacterium extorquens CM4 hypothetical protein YP_002422212.1 3650967 R 440085 CDS YP_002422213.1 218531397 7114223 3651662..3652210 1 NC_011757.1 PFAM: formaldehyde-activating enzyme (Fae); KEGG: mex:Mext_3143 formaldehyde-activating protein; formaldehyde-activating enzyme (Fae) 3652210 7114223 Mchl_3465 Methylobacterium extorquens CM4 formaldehyde-activating enzyme (Fae) YP_002422213.1 3651662 D 440085 CDS YP_002422214.1 218531398 7114224 3652317..3652577 1 NC_011757.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: mlo:mlr9262 hypothetical protein; CopG/Arc/MetJ family addiction module antidote protein 3652577 7114224 Mchl_3466 Methylobacterium extorquens CM4 CopG/Arc/MetJ family addiction module antidote protein YP_002422214.1 3652317 D 440085 CDS YP_002422215.1 218531399 7114225 3652574..3652870 1 NC_011757.1 PFAM: plasmid stabilization system; KEGG: smd:Smed_6483 addiction module toxin, RelE/StbE family; plasmid stabilization system 3652870 7114225 Mchl_3467 Methylobacterium extorquens CM4 plasmid stabilization system YP_002422215.1 3652574 D 440085 CDS YP_002422216.1 218531400 7114226 3652902..3653639 1 NC_011757.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mex:Mext_3144 RNA methyltransferase; TrmH family RNA methyltransferase 3653639 7114226 Mchl_3468 Methylobacterium extorquens CM4 TrmH family RNA methyltransferase YP_002422216.1 3652902 D 440085 CDS YP_002422217.1 218531401 7114227 complement(3653643..3653984) 1 NC_011757.1 KEGG: mpo:Mpop_3342 hypothetical protein; hypothetical protein 3653984 7114227 Mchl_3469 Methylobacterium extorquens CM4 hypothetical protein YP_002422217.1 3653643 R 440085 CDS YP_002422218.1 218531402 7114228 complement(3654014..3655027) 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_3146 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 3655027 7114228 Mchl_3470 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002422218.1 3654014 R 440085 CDS YP_002422219.1 218531403 7114229 complement(3655160..3656845) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_3147 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3656845 7114229 Mchl_3471 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002422219.1 3655160 R 440085 CDS YP_002422220.1 218531404 7114230 complement(3657355..3657903) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_3148 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 3657903 7114230 Mchl_3472 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002422220.1 3657355 R 440085 CDS YP_002422221.1 218531405 7114231 complement(3657911..3659218) 1 NC_011757.1 KEGG: mex:Mext_3149 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; O-acetylhomoserine/O-acetylserine sulfhydrylase 3659218 7114231 Mchl_3473 Methylobacterium extorquens CM4 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_002422221.1 3657911 R 440085 CDS YP_002422222.1 218531406 7114232 complement(3659362..3659748) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_3150 response regulator receiver; response regulator receiver protein 3659748 7114232 Mchl_3474 Methylobacterium extorquens CM4 response regulator receiver protein YP_002422222.1 3659362 R 440085 CDS YP_002422223.1 218531407 7114233 complement(3659862..3661259) 1 NC_011757.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: mex:Mext_3151 hypothetical protein; hypothetical protein 3661259 7114233 Mchl_3475 Methylobacterium extorquens CM4 hypothetical protein YP_002422223.1 3659862 R 440085 CDS YP_002422224.1 218531408 7114234 complement(3661414..3661782) 1 NC_011757.1 KEGG: mex:Mext_3152 hypothetical protein; hypothetical protein 3661782 7114234 Mchl_3476 Methylobacterium extorquens CM4 hypothetical protein YP_002422224.1 3661414 R 440085 CDS YP_002422225.1 218531409 7114235 3661990..3662940 1 NC_011757.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: mex:Mext_3153 alpha/beta hydrolase domain-containing protein; alpha/beta hydrolase fold-3 domain-containing protein 3662940 7114235 Mchl_3477 Methylobacterium extorquens CM4 alpha/beta hydrolase fold-3 domain-containing protein YP_002422225.1 3661990 D 440085 CDS YP_002422226.1 218531410 7114236 3662980..3665490 1 NC_011757.1 PFAM: helicase; DEAD/DEAH box helicase domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: mex:Mext_3154 DEAD/DEAH box helicase domain-containing protein; DEAD/DEAH box helicase 3665490 7114236 Mchl_3478 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002422226.1 3662980 D 440085 CDS YP_002422227.1 218531411 7114237 3665532..3666245 1 NC_011757.1 KEGG: mex:Mext_3155 ICC-like phosphoesterase; ICC-like phosphoesterase 3666245 7114237 Mchl_3479 Methylobacterium extorquens CM4 ICC-like phosphoesterase YP_002422227.1 3665532 D 440085 CDS YP_002422228.1 218531412 7114238 complement(3666359..3666796) 1 NC_011757.1 KEGG: mex:Mext_3156 hypothetical protein; hypothetical protein 3666796 7114238 Mchl_3480 Methylobacterium extorquens CM4 hypothetical protein YP_002422228.1 3666359 R 440085 CDS YP_002422229.1 218531413 7114239 3667097..3668422 1 NC_011757.1 PFAM: chloride channel core; KEGG: mex:Mext_3157 chloride channel core; chloride channel core 3668422 7114239 Mchl_3481 Methylobacterium extorquens CM4 chloride channel core YP_002422229.1 3667097 D 440085 CDS YP_002422230.1 218531414 7114240 3668496..3668675 1 NC_011757.1 PFAM: protein of unknown function DUF1328; KEGG: mex:Mext_3158 hypothetical protein; hypothetical protein 3668675 7114240 Mchl_3482 Methylobacterium extorquens CM4 hypothetical protein YP_002422230.1 3668496 D 440085 CDS YP_002422231.1 218531415 7114241 3668691..3669536 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3159 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3669536 7114241 Mchl_3483 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422231.1 3668691 D 440085 CDS YP_002422232.1 218531416 7114242 complement(3669706..3670683) 1 NC_011757.1 KEGG: mex:Mext_3160 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; thiamine-monophosphate kinase 3670683 7114242 Mchl_3484 Methylobacterium extorquens CM4 thiamine-monophosphate kinase YP_002422232.1 3669706 R 440085 CDS YP_002422233.1 218531417 7114243 complement(3670689..3671204) 1 NC_011757.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: mex:Mext_3161 transcription antitermination factor NusB; NusB antitermination factor 3671204 7114243 Mchl_3485 Methylobacterium extorquens CM4 NusB antitermination factor YP_002422233.1 3670689 R 440085 CDS YP_002422234.1 218531418 7114244 complement(3671201..3671722) 1 NC_011757.1 KEGG: mex:Mext_3162 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase 3671722 7114244 Mchl_3486 Methylobacterium extorquens CM4 6,7-dimethyl-8-ribityllumazine synthase YP_002422234.1 3671201 R 440085 CDS YP_002422235.1 218531419 7114245 3672035..3673561 1 NC_011757.1 PFAM: UbiA prenyltransferase; KEGG: mex:Mext_3163 hypothetical protein; hypothetical protein 3673561 7114245 Mchl_3487 Methylobacterium extorquens CM4 hypothetical protein YP_002422235.1 3672035 D 440085 CDS YP_002422236.1 218531420 7114246 3673561..3673986 1 NC_011757.1 PFAM: GtrA family protein; KEGG: mex:Mext_3164 GtrA family protein; GtrA family protein 3673986 7114246 Mchl_3488 Methylobacterium extorquens CM4 GtrA family protein YP_002422236.1 3673561 D 440085 CDS YP_002422237.1 218531421 7114247 complement(3673974..3675194) 1 NC_011757.1 KEGG: mex:Mext_3165 hypothetical protein; hypothetical protein 3675194 7114247 Mchl_3489 Methylobacterium extorquens CM4 hypothetical protein YP_002422237.1 3673974 R 440085 CDS YP_002422238.1 218531422 7114248 3675489..3676010 1 NC_011757.1 KEGG: mex:Mext_3166 hypothetical protein; hypothetical protein 3676010 7114248 Mchl_3490 Methylobacterium extorquens CM4 hypothetical protein YP_002422238.1 3675489 D 440085 CDS YP_002422239.1 218531423 7114249 complement(3676024..3676662) 1 NC_011757.1 TIGRFAM: riboflavin synthase, subunit alpha; PFAM: Lumazine-binding protein; KEGG: mex:Mext_3167 riboflavin synthase, alpha subunit; riboflavin synthase subunit alpha 3676662 7114249 Mchl_3491 Methylobacterium extorquens CM4 riboflavin synthase subunit alpha YP_002422239.1 3676024 R 440085 CDS YP_002422240.1 218531424 7114250 complement(3676664..3677794) 1 NC_011757.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: mex:Mext_3168 riboflavin biosynthesis protein RibD; riboflavin biosynthesis protein RibD 3677794 7114250 Mchl_3492 Methylobacterium extorquens CM4 riboflavin biosynthesis protein RibD YP_002422240.1 3676664 R 440085 CDS YP_002422241.1 218531425 7114251 complement(3677791..3678348) 1 NC_011757.1 PFAM: ATP-cone domain protein; KEGG: mex:Mext_3169 ATP-cone domain-containing protein; NrdR family transcriptional regulator 3678348 nrdR 7114251 nrdR Methylobacterium extorquens CM4 NrdR family transcriptional regulator YP_002422241.1 3677791 R 440085 CDS YP_002422242.1 218531426 7114252 complement(3678430..3678981) 1 NC_011757.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mpo:Mpop_3365 transcriptional regulator, BadM/Rrf2 family; BadM/Rrf2 family transcriptional regulator 3678981 7114252 Mchl_3494 Methylobacterium extorquens CM4 BadM/Rrf2 family transcriptional regulator YP_002422242.1 3678430 R 440085 CDS YP_002422243.1 218531427 7114253 complement(3679135..3680439) 1 NC_011757.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3680439 glyA 7114253 glyA Methylobacterium extorquens CM4 serine hydroxymethyltransferase YP_002422243.1 3679135 R 440085 CDS YP_002422244.1 218531428 7114254 complement(3680806..3681294) 1 NC_011757.1 PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: mex:Mext_3172 H+transporting two-sector ATPase B/B' subunit; H+transporting two-sector ATPase B/B' subunit 3681294 7114254 Mchl_3496 Methylobacterium extorquens CM4 H+transporting two-sector ATPase B/B' subunit YP_002422244.1 3680806 R 440085 CDS YP_002422245.1 218531429 7114255 complement(3681382..3681987) 1 NC_011757.1 PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: mex:Mext_3173 H+transporting two-sector ATPase B/B' subunit; H+transporting two-sector ATPase B/B' subunit 3681987 7114255 Mchl_3497 Methylobacterium extorquens CM4 H+transporting two-sector ATPase B/B' subunit YP_002422245.1 3681382 R 440085 CDS YP_002422246.1 218531430 7114256 complement(3682185..3682412) 1 NC_011757.1 PFAM: H+transporting two-sector ATPase C subunit; KEGG: mex:Mext_3174 H+transporting two-sector ATPase C subunit; H+transporting two-sector ATPase C subunit 3682412 7114256 Mchl_3498 Methylobacterium extorquens CM4 H+transporting two-sector ATPase C subunit YP_002422246.1 3682185 R 440085 CDS YP_002422247.1 218531431 7114257 complement(3682473..3683228) 1 NC_011757.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 3683228 7114257 Mchl_3499 Methylobacterium extorquens CM4 F0F1 ATP synthase subunit A YP_002422247.1 3682473 R 440085 CDS YP_002422248.1 218531432 7114258 complement(3683349..3683717) 1 NC_011757.1 KEGG: mex:Mext_3176 hypothetical protein; hypothetical protein 3683717 7114258 Mchl_3500 Methylobacterium extorquens CM4 hypothetical protein YP_002422248.1 3683349 R 440085 CDS YP_002422249.1 218531433 7114259 complement(3683881..3684534) 1 NC_011757.1 KEGG: mex:Mext_3177 DsbA oxidoreductase; DsbA oxidoreductase 3684534 7114259 Mchl_3501 Methylobacterium extorquens CM4 DsbA oxidoreductase YP_002422249.1 3683881 R 440085 CDS YP_002422250.1 218531434 7114260 complement(3684809..3685285) 1 NC_011757.1 PFAM: protein of unknown function DUF721; KEGG: mex:Mext_3178 hypothetical protein; hypothetical protein 3685285 7114260 Mchl_3502 Methylobacterium extorquens CM4 hypothetical protein YP_002422250.1 3684809 R 440085 CDS YP_002422251.1 218531435 7114261 complement(3685418..3685741) 1 NC_011757.1 KEGG: mex:Mext_3179 hypothetical protein; hypothetical protein 3685741 7114261 Mchl_3503 Methylobacterium extorquens CM4 hypothetical protein YP_002422251.1 3685418 R 440085 CDS YP_002422252.1 218531436 7114262 3685777..3687102 1 NC_011757.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; A/G-specific adenine glycosylase MutY; KEGG: mex:Mext_3180 A/G-specific adenine glycosylase; A/G-specific adenine glycosylase 3687102 7114262 Mchl_3504 Methylobacterium extorquens CM4 A/G-specific adenine glycosylase YP_002422252.1 3685777 D 440085 CDS YP_002422253.1 218531437 7114263 complement(3687166..3688362) 1 NC_011757.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mex:Mext_3181 DNA methylase N-4/N-6 domain-containing protein; DNA methylase N-4/N-6 domain-containing protein 3688362 7114263 Mchl_3505 Methylobacterium extorquens CM4 DNA methylase N-4/N-6 domain-containing protein YP_002422253.1 3687166 R 440085 CDS YP_002422254.1 218531438 7114264 3688792..3689139 1 NC_011757.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: mex:Mext_3182 lipoprotein A; lipoprotein A 3689139 7114264 Mchl_3506 Methylobacterium extorquens CM4 lipoprotein A YP_002422254.1 3688792 D 440085 CDS YP_002422255.1 218531439 7114265 3689267..3689584 1 NC_011757.1 KEGG: mex:Mext_3183 hypothetical protein; hypothetical protein 3689584 7114265 Mchl_3507 Methylobacterium extorquens CM4 hypothetical protein YP_002422255.1 3689267 D 440085 CDS YP_002422256.1 218531440 7114266 3689692..3689913 1 NC_011757.1 KEGG: mex:Mext_3184 hypothetical protein; hypothetical protein 3689913 7114266 Mchl_3508 Methylobacterium extorquens CM4 hypothetical protein YP_002422256.1 3689692 D 440085 CDS YP_002422257.1 218531441 7114267 3690087..3691910 1 NC_011757.1 PFAM: SMC domain protein; ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3185 ABC transporter; ABC transporter 3691910 7114267 Mchl_3509 Methylobacterium extorquens CM4 ABC transporter YP_002422257.1 3690087 D 440085 CDS YP_002422258.1 218531442 7114268 3692237..3693898 1 NC_011757.1 PFAM: porin; KEGG: mex:Mext_3186 porin; porin 3693898 7114268 Mchl_3510 Methylobacterium extorquens CM4 porin YP_002422258.1 3692237 D 440085 CDS YP_002422259.1 218531443 7114269 3694115..3696121 1 NC_011757.1 KEGG: mex:Mext_3187 hypothetical protein; hypothetical protein 3696121 7114269 Mchl_3511 Methylobacterium extorquens CM4 hypothetical protein YP_002422259.1 3694115 D 440085 CDS YP_002422260.1 218531444 7114270 complement(3696164..3697399) 1 NC_011757.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mex:Mext_3188 adenylyl cyclase class-3/4/guanylyl cyclase; adenylate/guanylate cyclase 3697399 7114270 Mchl_3512 Methylobacterium extorquens CM4 adenylate/guanylate cyclase YP_002422260.1 3696164 R 440085 CDS YP_002422261.1 218531445 7114271 3697540..3698145 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: mex:Mext_3189 metal-dependent phosphohydrolase; metal dependent phosphohydrolase 3698145 7114271 Mchl_3513 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002422261.1 3697540 D 440085 CDS YP_002422262.1 218531446 7114272 complement(3698169..3700493) 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mex:Mext_3190 lytic transglycosylase catalytic; lytic transglycosylase 3700493 7114272 Mchl_3514 Methylobacterium extorquens CM4 lytic transglycosylase YP_002422262.1 3698169 R 440085 CDS YP_002422263.1 218531447 7114273 3700693..3701583 1 NC_011757.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3701583 7114273 Mchl_3515 Methylobacterium extorquens CM4 dihydrodipicolinate synthase YP_002422263.1 3700693 D 440085 CDS YP_002422264.1 218531448 7114274 3701686..3702159 1 NC_011757.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3702159 smpB 7114274 smpB Methylobacterium extorquens CM4 SsrA-binding protein YP_002422264.1 3701686 D 440085 CDS YP_002422265.1 218531449 7114275 complement(3702381..3703037) 1 NC_011757.1 PFAM: protein of unknown function DUF88; KEGG: mex:Mext_3193 hypothetical protein; hypothetical protein 3703037 7114275 Mchl_3517 Methylobacterium extorquens CM4 hypothetical protein YP_002422265.1 3702381 R 440085 CDS YP_002422266.1 218531450 7114276 complement(3703538..3704128) 1 NC_011757.1 TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mex:Mext_3194 orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 3704128 7114276 Mchl_3518 Methylobacterium extorquens CM4 orotate phosphoribosyltransferase YP_002422266.1 3703538 R 440085 CDS YP_002422267.1 218531451 7114277 complement(3704343..3704690) 1 NC_011757.1 KEGG: mex:Mext_3195 hypothetical protein; hypothetical protein 3704690 7114277 Mchl_3519 Methylobacterium extorquens CM4 hypothetical protein YP_002422267.1 3704343 R 440085 CDS YP_002422268.1 218531452 7114278 complement(3704805..3707036) 1 NC_011757.1 KEGG: mex:Mext_3196 RelA/SpoT family protein; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I SpoT/RelA 3707036 7114278 Mchl_3520 Methylobacterium extorquens CM4 (p)ppGpp synthetase I SpoT/RelA YP_002422268.1 3704805 R 440085 CDS YP_002422269.1 218531453 7113653 complement(3707407..3707817) 1 NC_011757.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas; DNA-directed RNA polymerase subunit omega 3707817 7113653 Mchl_3521 Methylobacterium extorquens CM4 DNA-directed RNA polymerase subunit omega YP_002422269.1 3707407 R 440085 CDS YP_002422270.1 218531454 7113655 3708021..3708587 1 NC_011757.1 PFAM: nitrogen-fixing NifU domain protein; Scaffold protein Nfu/NifU; KEGG: mex:Mext_3198 scaffold protein Nfu/NifU; Scaffold protein Nfu/NifU 3708587 7113655 Mchl_3522 Methylobacterium extorquens CM4 Scaffold protein Nfu/NifU YP_002422270.1 3708021 D 440085 CDS YP_002422271.1 218531455 7113656 3708745..3709425 1 NC_011757.1 PFAM: peptidase M22 glycoprotease; KEGG: mex:Mext_3199 peptidase M22 glycoprotease; peptidase M22 glycoprotease 3709425 7113656 Mchl_3523 Methylobacterium extorquens CM4 peptidase M22 glycoprotease YP_002422271.1 3708745 D 440085 CDS YP_002422272.1 218531456 7113657 3709422..3709943 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mpo:Mpop_3396 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 3709943 7113657 Mchl_3524 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002422272.1 3709422 D 440085 CDS YP_002422273.1 218531457 7113658 3709969..3710847 1 NC_011757.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: mex:Mext_3201 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 3710847 7113658 Mchl_3525 Methylobacterium extorquens CM4 phospholipid/glycerol acyltransferase YP_002422273.1 3709969 D 440085 CDS YP_002422274.1 218531458 7113659 complement(3710852..3711295) 1 NC_011757.1 PFAM: MEKHLA domain protein; KEGG: mex:Mext_3202 MEKHLA domain-containing protein; MEKHLA domain-containing protein 3711295 7113659 Mchl_3526 Methylobacterium extorquens CM4 MEKHLA domain-containing protein YP_002422274.1 3710852 R 440085 CDS YP_002422275.1 218531459 7113660 3711394..3711942 1 NC_011757.1 PFAM: membrane-flanked domain; KEGG: mex:Mext_3203 hypothetical protein; membrane-flanked domain 3711942 7113660 Mchl_3527 Methylobacterium extorquens CM4 membrane-flanked domain YP_002422275.1 3711394 D 440085 CDS YP_002422276.1 218531460 7113661 3712011..3713399 1 NC_011757.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3713399 7113661 Mchl_3528 Methylobacterium extorquens CM4 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002422276.1 3712011 D 440085 CDS YP_002422277.1 218531461 7113662 3713436..3714542 1 NC_011757.1 PFAM: PhoH family protein; KEGG: mex:Mext_3205 PhoH family protein; PhoH family protein 3714542 7113662 Mchl_3529 Methylobacterium extorquens CM4 PhoH family protein YP_002422277.1 3713436 D 440085 CDS YP_002422278.1 218531462 7113663 3714613..3715098 1 NC_011757.1 PFAM: protein of unknown function UPF0054; KEGG: mex:Mext_3206 hypothetical protein; hypothetical protein 3715098 7113663 Mchl_3530 Methylobacterium extorquens CM4 hypothetical protein YP_002422278.1 3714613 D 440085 CDS YP_002422279.1 218531463 7113664 3715135..3716283 1 NC_011757.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: mex:Mext_3207 CBS domain-containing protein; CBS domain-containing protein 3716283 7113664 Mchl_3531 Methylobacterium extorquens CM4 CBS domain-containing protein YP_002422279.1 3715135 D 440085 CDS YP_002422280.1 218531464 7113665 3716312..3718015 1 NC_011757.1 transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 3718015 lnt 7113665 lnt Methylobacterium extorquens CM4 apolipoprotein N-acyltransferase YP_002422280.1 3716312 D 440085 CDS YP_002422281.1 218531465 7113666 3718162..3718971 1 NC_011757.1 PFAM: BA14K family protein; KEGG: mex:Mext_3209 hypothetical protein; BA14K family protein 3718971 7113666 Mchl_3533 Methylobacterium extorquens CM4 BA14K family protein YP_002422281.1 3718162 D 440085 CDS YP_002422282.1 218531466 7113667 complement(3719082..3720674) 1 NC_011757.1 PFAM: catalase; KEGG: mex:Mext_3210 catalase; catalase 3720674 7113667 Mchl_3534 Methylobacterium extorquens CM4 catalase YP_002422282.1 3719082 R 440085 CDS YP_002422283.1 218531467 7113668 3720822..3721793 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3211 LysR substrate-binding; LysR family transcriptional regulator 3721793 7113668 Mchl_3535 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422283.1 3720822 D 440085 CDS YP_002422284.1 218531468 7113669 3721947..3723002 1 NC_011757.1 TIGRFAM: membrane protein AbrB duplication; PFAM: ammonia monooxygenase; KEGG: mex:Mext_3212 membrane protein AbrB duplication; membrane protein 3723002 7113669 Mchl_3536 Methylobacterium extorquens CM4 membrane protein YP_002422284.1 3721947 D 440085 CDS YP_002422285.1 218531469 7113670 3722999..3723343 1 NC_011757.1 PFAM: diacylglycerol kinase; KEGG: mex:Mext_3213 diacylglycerol kinase; diacylglycerol kinase 3723343 7113670 Mchl_3537 Methylobacterium extorquens CM4 diacylglycerol kinase YP_002422285.1 3722999 D 440085 CDS YP_002422286.1 218531470 7113671 complement(3723366..3723563) 1 NC_011757.1 KEGG: mex:Mext_3214 hypothetical protein; hypothetical protein 3723563 7113671 Mchl_3538 Methylobacterium extorquens CM4 hypothetical protein YP_002422286.1 3723366 R 440085 CDS YP_002422287.1 218531471 7113672 complement(3723560..3723760) 1 NC_011757.1 KEGG: mex:Mext_3215 hypothetical protein; hypothetical protein 3723760 7113672 Mchl_3539 Methylobacterium extorquens CM4 hypothetical protein YP_002422287.1 3723560 R 440085 CDS YP_002422288.1 218531472 7113673 3724035..3724592 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_3216 metallophosphoesterase; metallophosphoesterase 3724592 7113673 Mchl_3540 Methylobacterium extorquens CM4 metallophosphoesterase YP_002422288.1 3724035 D 440085 CDS YP_002422289.1 218531473 7113674 complement(3724602..3725462) 1 NC_011757.1 KEGG: mex:Mext_3217 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; glutamate racemase 3725462 7113674 Mchl_3541 Methylobacterium extorquens CM4 glutamate racemase YP_002422289.1 3724602 R 440085 CDS YP_002422290.1 218531474 7113675 3725688..3726950 1 NC_011757.1 PFAM: protein of unknown function DUF323; KEGG: mex:Mext_3218 hypothetical protein; hypothetical protein 3726950 7113675 Mchl_3542 Methylobacterium extorquens CM4 hypothetical protein YP_002422290.1 3725688 D 440085 CDS YP_002422291.1 218531475 7113676 3727008..3727985 1 NC_011757.1 TIGRFAM: methyltransferase; KEGG: mex:Mext_3219 hypothetical protein; methyltransferase 3727985 7113676 Mchl_3543 Methylobacterium extorquens CM4 methyltransferase YP_002422291.1 3727008 D 440085 CDS YP_002422292.1 218531476 7113677 3728260..3730401 1 NC_011757.1 KEGG: mex:Mext_3220 hypothetical protein; hypothetical protein 3730401 7113677 Mchl_3544 Methylobacterium extorquens CM4 hypothetical protein YP_002422292.1 3728260 D 440085 CDS YP_002422293.1 218531477 7113678 complement(3730451..3730891) 1 NC_011757.1 PFAM: protein of unknown function DUF779; KEGG: mex:Mext_3221 hypothetical protein; hypothetical protein 3730891 7113678 Mchl_3545 Methylobacterium extorquens CM4 hypothetical protein YP_002422293.1 3730451 R 440085 CDS YP_002422294.1 218531478 7113679 3731114..3733801 1 NC_011757.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: mex:Mext_3222 nitrate reductase; nitrate reductase 3733801 7113679 Mchl_3546 Methylobacterium extorquens CM4 nitrate reductase YP_002422294.1 3731114 D 440085 CDS YP_002422295.1 218531479 7113680 3733917..3735374 1 NC_011757.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mex:Mext_3223 uroporphyrin-III C-methyltransferase; uroporphyrin-III C-methyltransferase 3735374 7113680 Mchl_3547 Methylobacterium extorquens CM4 uroporphyrin-III C-methyltransferase YP_002422295.1 3733917 D 440085 CDS YP_002422296.1 218531480 7113681 3735660..3736262 1 NC_011757.1 PFAM: electron transporter SCO1/SenC; KEGG: mex:Mext_3224 electron transporter SCO1/SenC; electron transporter SCO1/SenC 3736262 7113681 Mchl_3548 Methylobacterium extorquens CM4 electron transporter SCO1/SenC YP_002422296.1 3735660 D 440085 CDS YP_002422297.1 218531481 7113682 complement(3736213..3738057) 1 NC_011757.1 KEGG: mex:Mext_3225 glycosyl transferase; glycosyl transferase 3738057 7113682 Mchl_3549 Methylobacterium extorquens CM4 glycosyl transferase YP_002422297.1 3736213 R 440085 CDS YP_002422298.1 218531482 7113683 3738178..3739101 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_3226 extracellular solute-binding protein; family 3 extracellular solute-binding protein 3739101 7113683 Mchl_3550 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002422298.1 3738178 D 440085 CDS YP_002422299.1 218531483 7113684 3739197..3739403 1 NC_011757.1 KEGG: mex:Mext_3227 hypothetical protein; hypothetical protein 3739403 7113684 Mchl_3551 Methylobacterium extorquens CM4 hypothetical protein YP_002422299.1 3739197 D 440085 CDS YP_002422300.1 218531484 7113685 complement(3739427..3739837) 1 NC_011757.1 KEGG: mex:Mext_3228 hypothetical protein; hypothetical protein 3739837 7113685 Mchl_3552 Methylobacterium extorquens CM4 hypothetical protein YP_002422300.1 3739427 R 440085 CDS YP_002422301.1 218531485 7113686 complement(3739931..3741838) 1 NC_011757.1 KEGG: mex:Mext_3229 cobalt chelatase, pCobT subunit; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase CobT subunit; SMART: von Willebrand factor type A; cobalt chelatase, pCobT subunit 3741838 7113686 Mchl_3553 Methylobacterium extorquens CM4 cobalt chelatase, pCobT subunit YP_002422301.1 3739931 R 440085 CDS YP_002422302.1 218531486 7113687 complement(3741959..3742942) 1 NC_011757.1 KEGG: mex:Mext_3230 cobalt chelatase, pCobS small subunit; TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities AAA_5; cobalt chelatase, pCobS small subunit 3742942 7113687 Mchl_3554 Methylobacterium extorquens CM4 cobalt chelatase, pCobS small subunit YP_002422302.1 3741959 R 440085 CDS YP_002422303.1 218531487 7113688 complement(3743282..3743989) 1 NC_011757.1 PFAM: heat shock protein DnaJ domain protein; KEGG: mex:Mext_3231 heat shock protein DnaJ domain-containing protein; heat shock protein DnaJ domain-containing protein 3743989 7113688 Mchl_3555 Methylobacterium extorquens CM4 heat shock protein DnaJ domain-containing protein YP_002422303.1 3743282 R 440085 CDS YP_002422304.1 218531488 7113689 3744157..3744435 1 NC_011757.1 PFAM: BolA family protein; KEGG: mex:Mext_3232 BolA family protein; BolA family protein 3744435 7113689 Mchl_3556 Methylobacterium extorquens CM4 BolA family protein YP_002422304.1 3744157 D 440085 CDS YP_002422305.1 218531489 7113690 3744467..3744889 1 NC_011757.1 PFAM: class I peptide chain release factor; KEGG: mex:Mext_3233 class I peptide chain release factor; class I peptide chain release factor 3744889 7113690 Mchl_3557 Methylobacterium extorquens CM4 class I peptide chain release factor YP_002422305.1 3744467 D 440085 CDS YP_002422306.1 218531490 7113691 complement(3744903..3745661) 1 NC_011757.1 PFAM: protein of unknown function DUF1275; KEGG: mex:Mext_3234 hypothetical protein; hypothetical protein 3745661 7113691 Mchl_3558 Methylobacterium extorquens CM4 hypothetical protein YP_002422306.1 3744903 R 440085 CDS YP_002422307.1 218531491 7113692 complement(3745697..3746692) 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_3235 methyltransferase type 12; type 12 methyltransferase 3746692 7113692 Mchl_3559 Methylobacterium extorquens CM4 type 12 methyltransferase YP_002422307.1 3745697 R 440085 CDS YP_002422308.1 218531492 7113693 3746738..3747796 1 NC_011757.1 KEGG: mex:Mext_3236 mRNA 3-end processing factor; mRNA 3-end processing factor 3747796 7113693 Mchl_3560 Methylobacterium extorquens CM4 mRNA 3-end processing factor YP_002422308.1 3746738 D 440085 CDS YP_002422309.1 218531493 7113694 3747793..3749637 1 NC_011757.1 PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mex:Mext_3237 ATP dependent DNA ligase; ATP dependent DNA ligase 3749637 7113694 Mchl_3561 Methylobacterium extorquens CM4 ATP dependent DNA ligase YP_002422309.1 3747793 D 440085 CDS YP_002422310.1 218531494 7113695 3749634..3750116 1 NC_011757.1 PFAM: protein of unknown function UPF0047; KEGG: mex:Mext_3238 hypothetical protein; hypothetical protein 3750116 7113695 Mchl_3562 Methylobacterium extorquens CM4 hypothetical protein YP_002422310.1 3749634 D 440085 CDS YP_002422311.1 218531495 7113696 complement(3750125..3750571) 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_3239 hypothetical protein; hypothetical protein 3750571 7113696 Mchl_3563 Methylobacterium extorquens CM4 hypothetical protein YP_002422311.1 3750125 R 440085 CDS YP_002422312.1 218531496 7113697 complement(3750694..3750858) 1 NC_011757.1 PFAM: protein of unknown function UPF0057; KEGG: mex:Mext_3240 hypothetical protein; hypothetical protein 3750858 7113697 Mchl_3564 Methylobacterium extorquens CM4 hypothetical protein YP_002422312.1 3750694 R 440085 CDS YP_002422313.1 218531497 7113698 complement(3750961..3753162) 1 NC_011757.1 PFAM: enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_3241 3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-binding 3-hydroxyacyl-CoA dehydrogenase 3753162 7113698 Mchl_3565 Methylobacterium extorquens CM4 NAD-binding 3-hydroxyacyl-CoA dehydrogenase YP_002422313.1 3750961 R 440085 CDS YP_002422314.1 218531498 7113699 3753284..3754081 1 NC_011757.1 PFAM: EAL domain protein; KEGG: mex:Mext_3242 EAL domain-containing protein; diguanylate phosphodiesterase 3754081 7113699 Mchl_3566 Methylobacterium extorquens CM4 diguanylate phosphodiesterase YP_002422314.1 3753284 D 440085 CDS YP_002422315.1 218531499 7113700 complement(3754157..3754654) 1 NC_011757.1 KEGG: mex:Mext_3243 hypothetical protein; hypothetical protein 3754654 7113700 Mchl_3567 Methylobacterium extorquens CM4 hypothetical protein YP_002422315.1 3754157 R 440085 CDS YP_002422316.1 218531500 7113701 complement(3754782..3755990) 1 NC_011757.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 3755990 7113701 Mchl_3568 Methylobacterium extorquens CM4 acetyl-CoA acetyltransferase YP_002422316.1 3754782 R 440085 CDS YP_002422317.1 218531501 7113702 complement(3756164..3757954) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mex:Mext_3245 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 3757954 7113702 Mchl_3569 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002422317.1 3756164 R 440085 CDS YP_002422318.1 218531502 7113703 3758265..3761597 1 NC_011757.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mex:Mext_3246 Sel1 domain-containing protein; Sel1 domain-containing protein repeat-containing protein 3761597 7113703 Mchl_3570 Methylobacterium extorquens CM4 Sel1 domain-containing protein repeat-containing protein YP_002422318.1 3758265 D 440085 CDS YP_002422319.1 218531503 7113704 3762048..3762374 1 NC_011757.1 KEGG: mex:Mext_3247 hypothetical protein; hypothetical protein 3762374 7113704 Mchl_3571 Methylobacterium extorquens CM4 hypothetical protein YP_002422319.1 3762048 D 440085 CDS YP_002422320.1 218531504 7113705 complement(3762432..3763376) 1 NC_011757.1 KEGG: mex:Mext_3248 hypothetical protein; hypothetical protein 3763376 7113705 Mchl_3572 Methylobacterium extorquens CM4 hypothetical protein YP_002422320.1 3762432 R 440085 CDS YP_002422321.1 218531505 7113706 3763514..3764032 1 NC_011757.1 KEGG: mex:Mext_3249 hypothetical protein; hypothetical protein 3764032 7113706 Mchl_3573 Methylobacterium extorquens CM4 hypothetical protein YP_002422321.1 3763514 D 440085 CDS YP_002422322.1 218531506 7113707 3764029..3764832 1 NC_011757.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: mex:Mext_3250 phosphoesterase PA-phosphatase related; PA-phosphatase-like phosphoesterase 3764832 7113707 Mchl_3574 Methylobacterium extorquens CM4 PA-phosphatase-like phosphoesterase YP_002422322.1 3764029 D 440085 CDS YP_002422323.1 218531507 7113708 3764888..3766195 1 NC_011757.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: mex:Mext_3251 oxidoreductase domain-containing protein; oxidoreductase domain-containing protein 3766195 7113708 Mchl_3575 Methylobacterium extorquens CM4 oxidoreductase domain-containing protein YP_002422323.1 3764888 D 440085 CDS YP_002422324.1 218531508 7113709 complement(3766309..3766455) 1 NC_011757.1 KEGG: mex:Mext_3252 hypothetical protein; hypothetical protein 3766455 7113709 Mchl_3576 Methylobacterium extorquens CM4 hypothetical protein YP_002422324.1 3766309 R 440085 CDS YP_002422325.1 218531509 7113710 complement(3766538..3767833) 1 NC_011757.1 PFAM: peptidase M16 domain protein; KEGG: mex:Mext_3253 processing peptidase; processing peptidase 3767833 7113710 Mchl_3577 Methylobacterium extorquens CM4 processing peptidase YP_002422325.1 3766538 R 440085 CDS YP_002422326.1 218531510 7113711 complement(3768055..3769467) 1 NC_011757.1 KEGG: mex:Mext_3254 threonine synthase; TIGRFAM: threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; threonine synthase 3769467 7113711 Mchl_3578 Methylobacterium extorquens CM4 threonine synthase YP_002422326.1 3768055 R 440085 CDS YP_002422327.1 218531511 7113712 complement(3769553..3769966) 1 NC_011757.1 KEGG: mex:Mext_3255 hypothetical protein; hypothetical protein 3769966 7113712 Mchl_3579 Methylobacterium extorquens CM4 hypothetical protein YP_002422327.1 3769553 R 440085 CDS YP_002422328.1 218531512 7113713 complement(3770063..3770833) 1 NC_011757.1 PFAM: Surfeit locus 1 family protein; KEGG: mex:Mext_3256 surfeit locus 1 family protein; Surfeit locus 1 family protein 3770833 7113713 Mchl_3580 Methylobacterium extorquens CM4 Surfeit locus 1 family protein YP_002422328.1 3770063 R 440085 CDS YP_002422329.1 218531513 7113714 complement(3770833..3771207) 1 NC_011757.1 PFAM: protein of unknown function DUF983; KEGG: mex:Mext_3257 hypothetical protein; hypothetical protein 3771207 7113714 Mchl_3581 Methylobacterium extorquens CM4 hypothetical protein YP_002422329.1 3770833 R 440085 CDS YP_002422330.1 218531514 7113715 complement(3771331..3772188) 1 NC_011757.1 PFAM: cytochrome C oxidase subunit III; KEGG: mex:Mext_3258 cytochrome C oxidase subunit III; cytochrome C oxidase subunit III 3772188 7113715 Mchl_3582 Methylobacterium extorquens CM4 cytochrome C oxidase subunit III YP_002422330.1 3771331 R 440085 CDS YP_002422331.1 218531515 7113716 complement(3772335..3772943) 1 NC_011757.1 PFAM: cytochrome C oxidase assembly protein CtaG/Cox11; KEGG: mex:Mext_3259 cytochrome C oxidase assembly protein CtaG/Cox11; cytochrome C oxidase assembly protein CtaG/Cox11 3772943 7113716 Mchl_3583 Methylobacterium extorquens CM4 cytochrome C oxidase assembly protein CtaG/Cox11 YP_002422331.1 3772335 R 440085 CDS YP_002422332.1 218531516 7113717 complement(3772956..3773120) 1 NC_011757.1 KEGG: mex:Mext_3260 protein CoxF; protein CoxF 3773120 7113717 Mchl_3584 Methylobacterium extorquens CM4 protein CoxF YP_002422332.1 3772956 R 440085 CDS YP_002422333.1 218531517 7113718 complement(3773129..3774082) 1 NC_011757.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 3774082 7113718 Mchl_3585 Methylobacterium extorquens CM4 protoheme IX farnesyltransferase YP_002422333.1 3773129 R 440085 CDS YP_002422334.1 218531518 7113719 complement(3774248..3775876) 1 NC_011757.1 KEGG: mex:Mext_3262 cytochrome C oxidase subunit I; TIGRFAM: cytochrome C oxidase subunit I; PFAM: cytochrome C oxidase subunit I; cytochrome C oxidase subunit I 3775876 7113719 Mchl_3586 Methylobacterium extorquens CM4 cytochrome C oxidase subunit I YP_002422334.1 3774248 R 440085 CDS YP_002422335.1 218531519 7113720 complement(3775954..3776793) 1 NC_011757.1 KEGG: mex:Mext_3263 cytochrome C oxidase subunit II; TIGRFAM: cytochrome C oxidase subunit II; PFAM: cytochrome C oxidase subunit II; cytochrome C oxidase subunit II transmembrane region; cytochrome C oxidase subunit II 3776793 7113720 Mchl_3587 Methylobacterium extorquens CM4 cytochrome C oxidase subunit II YP_002422335.1 3775954 R 440085 CDS YP_002422336.1 218531520 7113721 3777049..3777924 1 NC_011757.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase subunit FdhD; KEGG: mex:Mext_3264 formate dehydrogenase family accessory protein FdhD; formate dehydrogenase family accessory protein FdhD 3777924 7113721 Mchl_3588 Methylobacterium extorquens CM4 formate dehydrogenase family accessory protein FdhD YP_002422336.1 3777049 D 440085 CDS YP_002422337.1 218531521 7113722 complement(3777950..3779002) 1 NC_011757.1 KEGG: mex:Mext_3265 hypothetical protein; hypothetical protein 3779002 7113722 Mchl_3589 Methylobacterium extorquens CM4 hypothetical protein YP_002422337.1 3777950 R 440085 CDS YP_002422338.1 218531522 7113723 3779639..3784357 1 NC_011757.1 PFAM: glutamine amidotransferase class-II; glutamate synthase subunit alpha domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mex:Mext_3266 glutamate synthase (ferredoxin); glutamate synthase (ferredoxin) 3784357 7113723 Mchl_3590 Methylobacterium extorquens CM4 glutamate synthase (ferredoxin) YP_002422338.1 3779639 D 440085 CDS YP_002422339.1 218531523 7113724 3784481..3785914 1 NC_011757.1 glutamate synthase is composed of subunits alpha and beta; subunit beta is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the subunit alpha, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3785914 gltD 7113724 gltD Methylobacterium extorquens CM4 glutamate synthase subunit beta YP_002422339.1 3784481 D 440085 CDS YP_002422340.1 218531524 7113725 complement(3785993..3786940) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_3268 beta-lactamase domain-containing protein; beta-lactamase 3786940 7113725 Mchl_3592 Methylobacterium extorquens CM4 beta-lactamase YP_002422340.1 3785993 R 440085 CDS YP_002422341.1 218531525 7113726 3787119..3788459 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mex:Mext_3269 ATPase domain-containing protein; histidine kinase 3788459 7113726 Mchl_3593 Methylobacterium extorquens CM4 histidine kinase YP_002422341.1 3787119 D 440085 CDS YP_002422342.1 218531526 7113727 3788468..3789127 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_3270 response regulator receiver; LuxR family transcriptional regulator 3789127 7113727 Mchl_3594 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002422342.1 3788468 D 440085 CDS YP_002422343.1 218531527 7113728 complement(3789155..3790612) 1 NC_011757.1 PFAM: protein of unknown function DUF459; KEGG: mex:Mext_3271 hypothetical protein; hypothetical protein 3790612 7113728 Mchl_3595 Methylobacterium extorquens CM4 hypothetical protein YP_002422343.1 3789155 R 440085 CDS YP_002422344.1 218531528 7113729 complement(3790883..3792064) 1 NC_011757.1 TIGRFAM: lytic murein transglycosylase; PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_3272 lytic murein transglycosylase; lytic murein transglycosylase 3792064 7113729 Mchl_3596 Methylobacterium extorquens CM4 lytic murein transglycosylase YP_002422344.1 3790883 R 440085 CDS YP_002422345.1 218531529 7113730 complement(3792061..3793053) 1 NC_011757.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3273 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 3793053 7113730 Mchl_3597 Methylobacterium extorquens CM4 UDP-glucose 4-epimerase YP_002422345.1 3792061 R 440085 CDS YP_002422346.1 218531530 7113731 3793211..3794092 1 NC_011757.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: nucleotidyl transferase; KEGG: mex:Mext_3274 UTP-glucose-1-phosphate uridylyltransferase; UTP-glucose-1-phosphate uridylyltransferase 3794092 7113731 Mchl_3598 Methylobacterium extorquens CM4 UTP-glucose-1-phosphate uridylyltransferase YP_002422346.1 3793211 D 440085 CDS YP_002422347.1 218531531 7113732 complement(3794334..3795230) 1 NC_011757.1 PFAM: N-formylglutamate amidohydrolase; KEGG: mex:Mext_3275 N-formylglutamate amidohydrolase; N-formylglutamate amidohydrolase 3795230 7113732 Mchl_3599 Methylobacterium extorquens CM4 N-formylglutamate amidohydrolase YP_002422347.1 3794334 R 440085 CDS YP_002422348.1 218531532 7113733 3795537..3795893 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mpo:Mpop_3474 response regulator receiver protein; response regulator receiver protein 3795893 7113733 Mchl_3600 Methylobacterium extorquens CM4 response regulator receiver protein YP_002422348.1 3795537 D 440085 CDS YP_002422349.1 218531533 7113734 3796120..3796377 1 NC_011757.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: mex:Mext_3277 glutaredoxin 3; glutaredoxin 3 3796377 7113734 Mchl_3601 Methylobacterium extorquens CM4 glutaredoxin 3 YP_002422349.1 3796120 D 440085 CDS YP_002422350.1 218531534 7113735 3796374..3797219 1 NC_011757.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mex:Mext_3278 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 3797219 7113735 Mchl_3602 Methylobacterium extorquens CM4 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_002422350.1 3796374 D 440085 CDS YP_002422351.1 218531535 7115428 3797340..3797816 1 NC_011757.1 PFAM: protein of unknown function DUF1178; KEGG: mex:Mext_3279 hypothetical protein; hypothetical protein 3797816 7115428 Mchl_3603 Methylobacterium extorquens CM4 hypothetical protein YP_002422351.1 3797340 D 440085 CDS YP_002422352.1 218531536 7115593 complement(3797835..3798899) 1 NC_011757.1 KEGG: mex:Mext_3280 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 3798899 7115593 Mchl_3604 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002422352.1 3797835 R 440085 CDS YP_002422353.1 218531537 7115594 3799075..3799734 1 NC_011757.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; KEGG: mex:Mext_3281 peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 3799734 7115594 Mchl_3605 Methylobacterium extorquens CM4 peptide methionine sulfoxide reductase YP_002422353.1 3799075 D 440085 CDS YP_002422354.1 218531538 7115595 3799839..3800342 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_3282 hypothetical protein; hypothetical protein 3800342 7115595 Mchl_3606 Methylobacterium extorquens CM4 hypothetical protein YP_002422354.1 3799839 D 440085 CDS YP_002422355.1 218531539 7115596 complement(3800350..3801279) 1 NC_011757.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 3801279 mepA 7115596 mepA Methylobacterium extorquens CM4 penicillin-insensitive murein endopeptidase YP_002422355.1 3800350 R 440085 CDS YP_002422356.1 218531540 7115597 3801406..3801801 1 NC_011757.1 PFAM: PRC-barrel domain protein; KEGG: mex:Mext_3285 PRC-barrel domain-containing protein; PRC-barrel domain-containing protein 3801801 7115597 Mchl_3608 Methylobacterium extorquens CM4 PRC-barrel domain-containing protein YP_002422356.1 3801406 D 440085 CDS YP_002422357.1 218531541 7115598 complement(3801832..3802179) 1 NC_011757.1 KEGG: mex:Mext_3286 hypothetical protein; hypothetical protein 3802179 7115598 Mchl_3609 Methylobacterium extorquens CM4 hypothetical protein YP_002422357.1 3801832 R 440085 CDS YP_002422358.1 218531542 7115599 complement(3802265..3803506) 1 NC_011757.1 PFAM: Na+/H+ antiporter NhaA; KEGG: mex:Mext_3287 Na+/H+ antiporter NhaA; Na+/H+ antiporter NhaA 3803506 7115599 Mchl_3610 Methylobacterium extorquens CM4 Na+/H+ antiporter NhaA YP_002422358.1 3802265 R 440085 CDS YP_002422359.1 218531543 7115600 complement(3803578..3804219) 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: mex:Mext_3288 redoxin domain-containing protein; redoxin 3804219 7115600 Mchl_3611 Methylobacterium extorquens CM4 redoxin YP_002422359.1 3803578 R 440085 CDS YP_002422360.1 218531544 7115601 3804259..3805650 1 NC_011757.1 TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_3289 argininosuccinate lyase; argininosuccinate lyase 3805650 7115601 Mchl_3612 Methylobacterium extorquens CM4 argininosuccinate lyase YP_002422360.1 3804259 D 440085 CDS YP_002422361.1 218531545 7115602 3805747..3806058 1 NC_011757.1 KEGG: mex:Mext_3290 hypothetical protein; hypothetical protein 3806058 7115602 Mchl_3613 Methylobacterium extorquens CM4 hypothetical protein YP_002422361.1 3805747 D 440085 CDS YP_002422362.1 218531546 7115603 3806214..3806897 1 NC_011757.1 KEGG: mex:Mext_3291 hypothetical protein; hypothetical protein 3806897 7115603 Mchl_3614 Methylobacterium extorquens CM4 hypothetical protein YP_002422362.1 3806214 D 440085 CDS YP_002422363.1 218531547 7115604 complement(3807076..3807330) 1 NC_011757.1 KEGG: mex:Mext_3292 hypothetical protein; hypothetical protein 3807330 7115604 Mchl_3615 Methylobacterium extorquens CM4 hypothetical protein YP_002422363.1 3807076 R 440085 CDS YP_002422364.1 218531548 7115605 complement(3807772..3808458) 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_3293 HAD family hydrolase; HAD-superfamily hydrolase 3808458 7115605 Mchl_3616 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002422364.1 3807772 R 440085 CDS YP_002422365.1 218531549 7115606 3808731..3810500 1 NC_011757.1 PFAM: carbamoyltransferase; KEGG: mex:Mext_3294 carbamoyltransferase; carbamoyltransferase 3810500 7115606 Mchl_3617 Methylobacterium extorquens CM4 carbamoyltransferase YP_002422365.1 3808731 D 440085 CDS YP_002422366.1 218531550 7115607 complement(3810543..3810887) 1 NC_011757.1 KEGG: mex:Mext_3295 hypothetical protein; hypothetical protein 3810887 7115607 Mchl_3618 Methylobacterium extorquens CM4 hypothetical protein YP_002422366.1 3810543 R 440085 CDS YP_002422367.1 218531551 7115608 complement(3810984..3811658) 1 NC_011757.1 KEGG: mex:Mext_3296 haloacid dehalogenase, type II; TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; haloacid dehalogenase, type II 3811658 7115608 Mchl_3619 Methylobacterium extorquens CM4 haloacid dehalogenase, type II YP_002422367.1 3810984 R 440085 CDS YP_002422368.1 218531552 7115609 complement(3811696..3813225) 1 NC_011757.1 TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: mex:Mext_3297 integral membrane protein MviN; integral membrane protein MviN 3813225 7115609 Mchl_3620 Methylobacterium extorquens CM4 integral membrane protein MviN YP_002422368.1 3811696 R 440085 CDS YP_002422369.1 218531553 7115610 complement(3813526..3814125) 1 NC_011757.1 PFAM: manganese and iron superoxide dismutase; KEGG: mex:Mext_3298 superoxide dismutase; superoxide dismutase 3814125 7115610 Mchl_3621 Methylobacterium extorquens CM4 superoxide dismutase YP_002422369.1 3813526 R 440085 CDS YP_002422370.1 218531554 7115611 3814495..3815481 1 NC_011757.1 KEGG: mex:Mext_3299 hypothetical protein; hypothetical protein 3815481 7115611 Mchl_3622 Methylobacterium extorquens CM4 hypothetical protein YP_002422370.1 3814495 D 440085 CDS YP_002422371.1 218531555 7115612 complement(3815551..3817302) 1 NC_011757.1 KEGG: mex:Mext_3300 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 3817302 7115612 Mchl_3623 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002422371.1 3815551 R 440085 CDS YP_002422372.1 218531556 7115613 complement(3817410..3818369) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_3301 glycosyl transferase; family 2 glycosyl transferase 3818369 7115613 Mchl_3624 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002422372.1 3817410 R 440085 CDS YP_002422373.1 218531557 7115614 complement(3818366..3819295) 1 NC_011757.1 KEGG: mex:Mext_3302 rhamnosyltransferase; rhamnosyltransferase 3819295 7115614 Mchl_3625 Methylobacterium extorquens CM4 rhamnosyltransferase YP_002422373.1 3818366 R 440085 CDS YP_002422374.1 218531558 7115615 complement(3819344..3820846) 1 NC_011757.1 PFAM: peptidase M48 Ste24p; KEGG: mex:Mext_3303 peptidase M48 Ste24p; peptidase M48 Ste24p 3820846 7115615 Mchl_3626 Methylobacterium extorquens CM4 peptidase M48 Ste24p YP_002422374.1 3819344 R 440085 CDS YP_002422375.1 218531559 7115616 complement(3820853..3821704) 1 NC_011757.1 KEGG: mex:Mext_3304 hypothetical protein; hypothetical protein 3821704 7115616 Mchl_3627 Methylobacterium extorquens CM4 hypothetical protein YP_002422375.1 3820853 R 440085 CDS YP_002422376.1 218531560 7115617 3822438..3822845 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_3305 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 3822845 7115617 Mchl_3628 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002422376.1 3822438 D 440085 CDS YP_002422377.1 218531561 7115618 3823053..3824228 1 NC_011757.1 PFAM: S-adenosylmethionine synthetase; KEGG: mex:Mext_3306 methionine adenosyltransferase; methionine adenosyltransferase 3824228 7115618 Mchl_3629 Methylobacterium extorquens CM4 methionine adenosyltransferase YP_002422377.1 3823053 D 440085 CDS YP_002422378.1 218531562 7115619 3824238..3824975 1 NC_011757.1 KEGG: mex:Mext_3307 tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 3824975 7115619 Mchl_3630 Methylobacterium extorquens CM4 tRNA (guanine-N(7)-)-methyltransferase YP_002422378.1 3824238 D 440085 CDS YP_002422379.1 218531563 7115620 complement(3825224..3827956) 1 NC_011757.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 3827956 7115620 Mchl_3631 Methylobacterium extorquens CM4 DNA topoisomerase I YP_002422379.1 3825224 R 440085 CDS YP_002422380.1 218531564 7115621 complement(3828105..3829052) 1 NC_011757.1 PFAM: oxidoreductase molybdopterin binding; KEGG: mex:Mext_3309 oxidoreductase molybdopterin binding; molybdopterin binding oxidoreductase 3829052 7115621 Mchl_3632 Methylobacterium extorquens CM4 molybdopterin binding oxidoreductase YP_002422380.1 3828105 R 440085 CDS YP_002422381.1 218531565 7115622 complement(3829049..3829921) 1 NC_011757.1 KEGG: mex:Mext_3310 transmembrane b-type cytochrome protein; transmembrane b-type cytochrome protein 3829921 7115622 Mchl_3633 Methylobacterium extorquens CM4 transmembrane b-type cytochrome protein YP_002422381.1 3829049 R 440085 CDS YP_002422382.1 218531566 7115623 complement(3830041..3830352) 1 NC_011757.1 KEGG: mex:Mext_3311 hypothetical protein; hypothetical protein 3830352 7115623 Mchl_3634 Methylobacterium extorquens CM4 hypothetical protein YP_002422382.1 3830041 R 440085 CDS YP_002422383.1 218531567 7115624 3830627..3831574 1 NC_011757.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 3831574 pyrB 7115624 pyrB Methylobacterium extorquens CM4 aspartate carbamoyltransferase catalytic subunit YP_002422383.1 3830627 D 440085 CDS YP_002422384.1 218531568 7115625 3831580..3832884 1 NC_011757.1 KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase; PFAM: amidohydrolase; amidohydrolase; dihydroorotase 3832884 7115625 Mchl_3636 Methylobacterium extorquens CM4 dihydroorotase YP_002422384.1 3831580 D 440085 CDS YP_002422385.1 218531569 7115626 3832881..3833489 1 NC_011757.1 PFAM: protein of unknown function DUF205; KEGG: mex:Mext_3314 hypothetical protein; hypothetical protein 3833489 7115626 Mchl_3637 Methylobacterium extorquens CM4 hypothetical protein YP_002422385.1 3832881 D 440085 CDS YP_002422386.1 218531570 7115627 3833521..3834714 1 NC_011757.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: mex:Mext_3315 DNA protecting protein DprA; DNA protecting protein DprA 3834714 7115627 Mchl_3638 Methylobacterium extorquens CM4 DNA protecting protein DprA YP_002422386.1 3833521 D 440085 CDS YP_002422387.1 218531571 7115628 3834742..3834936 1 NC_011757.1 hypothetical protein 3834936 7115628 Mchl_3639 Methylobacterium extorquens CM4 hypothetical protein YP_002422387.1 3834742 D 440085 CDS YP_002422388.1 218531572 7115629 3835037..3835864 1 NC_011757.1 PFAM: lipolytic protein G-D-S-L family; KEGG: mex:Mext_3316 GDSL family lipase; G-D-S-L family lipolytic protein 3835864 7115629 Mchl_3640 Methylobacterium extorquens CM4 G-D-S-L family lipolytic protein YP_002422388.1 3835037 D 440085 CDS YP_002422389.1 218531573 7115630 3835861..3837012 1 NC_011757.1 KEGG: mex:Mext_3317 hypothetical protein; hypothetical protein 3837012 7115630 Mchl_3641 Methylobacterium extorquens CM4 hypothetical protein YP_002422389.1 3835861 D 440085 CDS YP_002422390.1 218531574 7115631 3837103..3837777 1 NC_011757.1 PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_3318 ThiJ/PfpI domain-containing protein; ThiJ/PfpI domain-containing protein 3837777 7115631 Mchl_3642 Methylobacterium extorquens CM4 ThiJ/PfpI domain-containing protein YP_002422390.1 3837103 D 440085 CDS YP_002422391.1 218531575 7115632 complement(3837774..3838271) 1 NC_011757.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; KEGG: mex:Mext_3319 Holliday junction resolvase YqgF; Holliday junction resolvase YqgF 3838271 7115632 Mchl_3643 Methylobacterium extorquens CM4 Holliday junction resolvase YqgF YP_002422391.1 3837774 R 440085 CDS YP_002422392.1 218531576 7115633 complement(3838268..3838846) 1 NC_011757.1 KEGG: mex:Mext_3320 hypothetical protein; hypothetical protein 3838846 7115633 Mchl_3644 Methylobacterium extorquens CM4 hypothetical protein YP_002422392.1 3838268 R 440085 CDS YP_002422393.1 218531577 7115634 3839007..3839183 1 NC_011757.1 KEGG: mex:Mext_3321 hypothetical protein; hypothetical protein 3839183 7115634 Mchl_3645 Methylobacterium extorquens CM4 hypothetical protein YP_002422393.1 3839007 D 440085 CDS YP_002422394.1 218531578 7115635 3839342..3839629 1 NC_011757.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: mex:Mext_3322 glutamyl-tRNA(Gln) amidotransferase subunit C; glutamyl-tRNA(Gln) amidotransferase subunit C 3839629 7115635 Mchl_3646 Methylobacterium extorquens CM4 glutamyl-tRNA(Gln) amidotransferase subunit C YP_002422394.1 3839342 D 440085 CDS YP_002422395.1 218531579 7115636 3839726..3841207 1 NC_011757.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 3841207 gatA 7115636 gatA Methylobacterium extorquens CM4 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002422395.1 3839726 D 440085 CDS YP_002422396.1 218531580 7115637 3841204..3841509 1 NC_011757.1 KEGG: mex:Mext_3324 hypothetical protein; hypothetical protein 3841509 7115637 Mchl_3648 Methylobacterium extorquens CM4 hypothetical protein YP_002422396.1 3841204 D 440085 CDS YP_002422397.1 218531581 7115638 complement(3841568..3841963) 1 NC_011757.1 PFAM: excinuclease ABC C subunit domain protein; KEGG: mpo:Mpop_3525 excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain-containing protein 3841963 7115638 Mchl_3649 Methylobacterium extorquens CM4 excinuclease ABC C subunit domain-containing protein YP_002422397.1 3841568 R 440085 CDS YP_002422398.1 218531582 7115639 complement(3842036..3845206) 1 NC_011757.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_3326 hydrophobe/amphiphile efflux-1 (HAE1) family protein; hydrophobe/amphiphile efflux-1 (HAE1) family transporter 3845206 7115639 Mchl_3650 Methylobacterium extorquens CM4 hydrophobe/amphiphile efflux-1 (HAE1) family transporter YP_002422398.1 3842036 R 440085 CDS YP_002422399.1 218531583 7115640 complement(3845285..3846610) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3327 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 3846610 7115640 Mchl_3651 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422399.1 3845285 R 440085 CDS YP_002422400.1 218531584 7115641 complement(3846990..3847418) 1 NC_011757.1 KEGG: mex:Mext_3328 hypothetical protein; hypothetical protein 3847418 7115641 Mchl_3652 Methylobacterium extorquens CM4 hypothetical protein YP_002422400.1 3846990 R 440085 CDS YP_002422401.1 218531585 7115642 3847653..3848252 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_3329 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 3848252 7115642 Mchl_3653 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002422401.1 3847653 D 440085 CDS YP_002422402.1 218531586 7115643 3848835..3850157 1 NC_011757.1 KEGG: mex:Mext_3330 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; O-acetylhomoserine/O-acetylserine sulfhydrylase 3850157 7115643 Mchl_3654 Methylobacterium extorquens CM4 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_002422402.1 3848835 D 440085 CDS YP_002422403.1 218531587 7115644 3850159..3851181 1 NC_011757.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: mex:Mext_3331 2OG-Fe(II) oxygenase; 2OG-Fe(II) oxygenase 3851181 7115644 Mchl_3655 Methylobacterium extorquens CM4 2OG-Fe(II) oxygenase YP_002422403.1 3850159 D 440085 CDS YP_002422404.1 218531588 7115645 3851178..3851363 1 NC_011757.1 hypothetical protein 3851363 7115645 Mchl_3656 Methylobacterium extorquens CM4 hypothetical protein YP_002422404.1 3851178 D 440085 CDS YP_002422405.1 218531589 7115647 complement(3851925..3852197) 1 NC_011757.1 PFAM: Usg family protein; KEGG: mex:Mext_3333 Usg family protein; Usg family protein 3852197 7115647 Mchl_3658 Methylobacterium extorquens CM4 Usg family protein YP_002422405.1 3851925 R 440085 CDS YP_002422406.1 218531590 7115648 complement(3852584..3854206) 1 NC_011757.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: mex:Mext_3334 chaperonin GroEL; chaperonin GroEL 3854206 7115648 Mchl_3659 Methylobacterium extorquens CM4 chaperonin GroEL YP_002422406.1 3852584 R 440085 CDS YP_002422407.1 218531591 7115649 complement(3854242..3854532) 1 NC_011757.1 PFAM: chaperonin Cpn10; KEGG: mex:Mext_3335 chaperonin Cpn10; chaperonin Cpn10 3854532 7115649 Mchl_3660 Methylobacterium extorquens CM4 chaperonin Cpn10 YP_002422407.1 3854242 R 440085 CDS YP_002422408.1 218531592 7115650 complement(3854796..3856019) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_3336 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 3856019 7115650 Mchl_3661 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase type 2 domain-containing protein YP_002422408.1 3854796 R 440085 CDS YP_002422409.1 218531593 7115651 complement(3856309..3858717) 1 NC_011757.1 KEGG: mex:Mext_3337 hypothetical protein; hypothetical protein 3858717 7115651 Mchl_3662 Methylobacterium extorquens CM4 hypothetical protein YP_002422409.1 3856309 R 440085 CDS YP_002422410.1 218531594 7115652 3858863..3859903 1 NC_011757.1 KEGG: mex:Mext_3338 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components-like protein; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 3859903 7115652 Mchl_3663 Methylobacterium extorquens CM4 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_002422410.1 3858863 D 440085 CDS YP_002422411.1 218531595 7115653 3859917..3861125 1 NC_011757.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: mex:Mext_3339 oxidoreductase molybdopterin binding; molybdopterin binding oxidoreductase 3861125 7115653 Mchl_3664 Methylobacterium extorquens CM4 molybdopterin binding oxidoreductase YP_002422411.1 3859917 D 440085 CDS YP_002422412.1 218531596 7115654 3861115..3861699 1 NC_011757.1 KEGG: mex:Mext_3340 cytochrome C, class I; cytochrome C, class I 3861699 7115654 Mchl_3665 Methylobacterium extorquens CM4 cytochrome C, class I YP_002422412.1 3861115 D 440085 CDS YP_002422413.1 218531597 7115655 3861696..3862664 1 NC_011757.1 KEGG: mex:Mext_3341 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 3862664 7115655 Mchl_3666 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002422413.1 3861696 D 440085 CDS YP_002422414.1 218531598 7115656 3862661..3863716 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_3342 alkanesulfonate monooxygenase; alkanesulfonate monooxygenase 3863716 7115656 Mchl_3667 Methylobacterium extorquens CM4 alkanesulfonate monooxygenase YP_002422414.1 3862661 D 440085 CDS YP_002422415.1 218531599 7115657 3863713..3865122 1 NC_011757.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: mex:Mext_3343 xanthine permease; xanthine permease 3865122 7115657 Mchl_3668 Methylobacterium extorquens CM4 xanthine permease YP_002422415.1 3863713 D 440085 CDS YP_002422416.1 218531600 7115658 complement(3865038..3865694) 1 NC_011757.1 PFAM: DSBA oxidoreductase; KEGG: mex:Mext_3344 DsbA oxidoreductase; DSBA oxidoreductase 3865694 7115658 Mchl_3669 Methylobacterium extorquens CM4 DSBA oxidoreductase YP_002422416.1 3865038 R 440085 CDS YP_002422417.1 218531601 7115659 complement(3865691..3866572) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3345 ABC transporter; ABC transporter 3866572 7115659 Mchl_3670 Methylobacterium extorquens CM4 ABC transporter YP_002422417.1 3865691 R 440085 CDS YP_002422418.1 218531602 7115660 complement(3866569..3867432) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3346 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 3867432 7115660 Mchl_3671 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422418.1 3866569 R 440085 CDS YP_002422419.1 218531603 7115661 complement(3867429..3868871) 1 NC_011757.1 KEGG: mex:Mext_3347 ABC transporter substrate-binding protein; ABC transporter substrate-binding protein 3868871 7115661 Mchl_3672 Methylobacterium extorquens CM4 ABC transporter substrate-binding protein YP_002422419.1 3867429 R 440085 CDS YP_002422420.1 218531604 7115662 3869207..3869971 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_3348 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 3869971 7115662 Mchl_3673 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422420.1 3869207 D 440085 CDS YP_002422421.1 218531605 7115663 complement(3870151..3871122) 1 NC_011757.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein; KEGG: mex:Mext_3349 heat domain-containing protein; HEAT domain-containing protein 3871122 7115663 Mchl_3674 Methylobacterium extorquens CM4 HEAT domain-containing protein YP_002422421.1 3870151 R 440085 CDS YP_002422422.1 218531606 7115664 complement(3871128..3871361) 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mex:Mext_3350 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 3871361 7115664 Mchl_3675 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002422422.1 3871128 R 440085 CDS YP_002422423.1 218531607 7115665 complement(3871376..3873124) 1 NC_011757.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mex:Mext_3351 oxidoreductase; oxidoreductase 3873124 7115665 Mchl_3676 Methylobacterium extorquens CM4 oxidoreductase YP_002422423.1 3871376 R 440085 CDS YP_002422424.1 218531608 7115666 complement(3873136..3873459) 1 NC_011757.1 PFAM: protein of unknown function DUF971; KEGG: mex:Mext_3352 hypothetical protein; hypothetical protein 3873459 7115666 Mchl_3677 Methylobacterium extorquens CM4 hypothetical protein YP_002422424.1 3873136 R 440085 CDS YP_002422425.1 218531609 7115667 complement(3873996..3874169) 1 NC_011757.1 KEGG: mex:Mext_3353 hypothetical protein; hypothetical protein 3874169 7115667 Mchl_3678 Methylobacterium extorquens CM4 hypothetical protein YP_002422425.1 3873996 R 440085 CDS YP_002422426.1 218531610 7115668 complement(3874580..3876583) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_3354 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 3876583 7115668 Mchl_3679 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002422426.1 3874580 R 440085 CDS YP_002422427.1 218531611 7115669 3876976..3878043 1 NC_011757.1 KEGG: mex:Mext_3355 hypothetical protein; hypothetical protein 3878043 7115669 Mchl_3680 Methylobacterium extorquens CM4 hypothetical protein YP_002422427.1 3876976 D 440085 CDS YP_002422428.1 218531612 7115670 complement(3878913..3879965) 1 NC_011757.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 3879965 amiE 7115670 amiE Methylobacterium extorquens CM4 acylamide amidohydrolase YP_002422428.1 3878913 R 440085 CDS YP_002422429.1 218531613 7115671 complement(3880040..3881500) 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_3373 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 3881500 7115671 Mchl_3682 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002422429.1 3880040 R 440085 CDS YP_002422430.1 218531614 7115672 complement(3881667..3881984) 1 NC_011757.1 TIGRFAM: regulatory protein, FmdB family; PFAM: regulatory protein FmdB; KEGG: mex:Mext_3374 FmdB family regulatory protein; FmdB family regulatory protein 3881984 7115672 Mchl_3683 Methylobacterium extorquens CM4 FmdB family regulatory protein YP_002422430.1 3881667 R 440085 CDS YP_002422431.1 218531615 7115673 complement(3882049..3883278) 1 NC_011757.1 PFAM: acetamidase/formamidase; KEGG: mex:Mext_3375 formamidase; formamidase 3883278 7115673 Mchl_3684 Methylobacterium extorquens CM4 formamidase YP_002422431.1 3882049 R 440085 CDS YP_002422432.1 218531616 7115102 complement(3883442..3884458) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3376 hypothetical protein; hypothetical protein 3884458 7115102 Mchl_3685 Methylobacterium extorquens CM4 hypothetical protein YP_002422432.1 3883442 R 440085 CDS YP_002422433.1 218531617 7115347 complement(3884470..3885216) 1 NC_011757.1 KEGG: mex:Mext_3377 UreA ABC transporter ATP-binding protein UrtE; TIGRFAM: urea ABC transporter ATP-binding protein UrtE; PFAM: ABC transporter; SMART: ATPase AAA; urea ABC transporter ATP-binding protein UrtE 3885216 7115347 Mchl_3686 Methylobacterium extorquens CM4 urea ABC transporter ATP-binding protein UrtE YP_002422433.1 3884470 R 440085 CDS YP_002422434.1 218531618 7115348 complement(3885230..3886018) 1 NC_011757.1 TIGRFAM: urea ABC transporter ATP-binding protein UrtD; PFAM: ABC transporter; KEGG: mex:Mext_3378 UreA ABC transporter ATP-binding protein UrtD; urea ABC transporter ATP-binding protein UrtD 3886018 7115348 Mchl_3687 Methylobacterium extorquens CM4 urea ABC transporter ATP-binding protein UrtD YP_002422434.1 3885230 R 440085 CDS YP_002422435.1 218531619 7115349 complement(3886030..3887211) 1 NC_011757.1 TIGRFAM: urea ABC transporter permease UrtC; PFAM: inner-membrane translocator; KEGG: mex:Mext_3379 UreA ABC transporter permease UrtC; urea ABC transporter permease UrtC 3887211 7115349 Mchl_3688 Methylobacterium extorquens CM4 urea ABC transporter permease UrtC YP_002422435.1 3886030 R 440085 CDS YP_002422436.1 218531620 7115350 complement(3887225..3888151) 1 NC_011757.1 TIGRFAM: urea ABC transporter permease UrtB; PFAM: inner-membrane translocator; KEGG: mex:Mext_3380 UreA ABC transporter permease UrtB; urea ABC transporter permease UrtB 3888151 7115350 Mchl_3689 Methylobacterium extorquens CM4 urea ABC transporter permease UrtB YP_002422436.1 3887225 R 440085 CDS YP_002422437.1 218531621 7115351 complement(3888395..3889648) 1 NC_011757.1 TIGRFAM: urea ABC transporter urea binding protein; KEGG: mex:Mext_3381 ABC transporter substrate-binding protein; urea ABC transporter urea binding protein 3889648 7115351 Mchl_3690 Methylobacterium extorquens CM4 urea ABC transporter urea binding protein YP_002422437.1 3888395 R 440085 CDS YP_002422438.1 218531622 7115352 3890106..3893321 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_3382 ATPase domain-containing protein; histidine kinase 3893321 7115352 Mchl_3691 Methylobacterium extorquens CM4 histidine kinase YP_002422438.1 3890106 D 440085 CDS YP_002422439.1 218531623 7115353 3893314..3894216 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_3383 response regulator receiver; LuxR family transcriptional regulator 3894216 7115353 Mchl_3692 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002422439.1 3893314 D 440085 CDS YP_002422440.1 218531624 7115354 3894692..3895495 1 NC_011757.1 PFAM: invasion associated locus B family protein; KEGG: mex:Mext_3384 invasion associated locus B family protein; invasion associated locus B family protein 3895495 7115354 Mchl_3693 Methylobacterium extorquens CM4 invasion associated locus B family protein YP_002422440.1 3894692 D 440085 CDS YP_002422441.1 218531625 7115355 3896046..3896804 1 NC_011757.1 catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase 3896804 7115355 Mchl_3694 Methylobacterium extorquens CM4 precorrin 6A synthase YP_002422441.1 3896046 D 440085 CDS YP_002422442.1 218531626 7115356 3897029..3898366 1 NC_011757.1 KEGG: mex:Mext_3386 hypothetical protein; hypothetical protein 3898366 7115356 Mchl_3695 Methylobacterium extorquens CM4 hypothetical protein YP_002422442.1 3897029 D 440085 CDS YP_002422443.1 218531627 7115357 complement(3898386..3898952) 1 NC_011757.1 KEGG: mex:Mext_3387 hypothetical protein; hypothetical protein 3898952 7115357 Mchl_3696 Methylobacterium extorquens CM4 hypothetical protein YP_002422443.1 3898386 R 440085 CDS YP_002422444.1 218531628 7115358 3899313..3900002 1 NC_011757.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: mex:Mext_3388 cobyrinic acid ac-diamide synthase; cobyrinic acid ac-diamide synthase 3900002 7115358 Mchl_3697 Methylobacterium extorquens CM4 cobyrinic acid ac-diamide synthase YP_002422444.1 3899313 D 440085 CDS YP_002422445.1 218531629 7115359 3899986..3900339 1 NC_011757.1 KEGG: mex:Mext_3389 hypothetical protein; hypothetical protein 3900339 7115359 Mchl_3698 Methylobacterium extorquens CM4 hypothetical protein YP_002422445.1 3899986 D 440085 CDS YP_002422446.1 218531630 7115360 3900663..3902030 1 NC_011757.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: mex:Mext_3390 lipoprotein A; lipoprotein A 3902030 7115360 Mchl_3699 Methylobacterium extorquens CM4 lipoprotein A YP_002422446.1 3900663 D 440085 CDS YP_002422447.1 218531631 7115361 complement(3902210..3904078) 1 NC_011757.1 KEGG: mex:Mext_3391 hypothetical protein; hypothetical protein 3904078 7115361 Mchl_3700 Methylobacterium extorquens CM4 hypothetical protein YP_002422447.1 3902210 R 440085 CDS YP_002422448.1 218531632 7115362 complement(3904301..3904627) 1 NC_011757.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: mex:Mext_3392 iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly accessory protein 3904627 7115362 Mchl_3701 Methylobacterium extorquens CM4 iron-sulfur cluster assembly accessory protein YP_002422448.1 3904301 R 440085 CDS YP_002422449.1 218531633 7115363 3904754..3906007 1 NC_011757.1 KEGG: mex:Mext_3393 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; deoxyguanosinetriphosphate triphosphohydrolase 3906007 7115363 Mchl_3702 Methylobacterium extorquens CM4 deoxyguanosinetriphosphate triphosphohydrolase YP_002422449.1 3904754 D 440085 CDS YP_002422450.1 218531634 7115364 complement(3906035..3906574) 1 NC_011757.1 KEGG: mex:Mext_3394 hypothetical protein; hypothetical protein 3906574 7115364 Mchl_3703 Methylobacterium extorquens CM4 hypothetical protein YP_002422450.1 3906035 R 440085 CDS YP_002422451.1 218531635 7115365 3906719..3907180 1 NC_011757.1 PFAM: thioesterase superfamily protein; KEGG: mex:Mext_3395 thioesterase superfamily protein; thioesterase superfamily protein 3907180 7115365 Mchl_3704 Methylobacterium extorquens CM4 thioesterase superfamily protein YP_002422451.1 3906719 D 440085 CDS YP_002422452.1 218531636 7115366 3907275..3909032 1 NC_011757.1 KEGG: mex:Mext_3396 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; arginyl-tRNA synthetase 3909032 7115366 Mchl_3705 Methylobacterium extorquens CM4 arginyl-tRNA synthetase YP_002422452.1 3907275 D 440085 CDS YP_002422453.1 218531637 7115367 3909062..3910480 1 NC_011757.1 PFAM: sporulation domain protein; KEGG: mex:Mext_3397 sporulation domain-containing protein; sporulation domain-containing protein 3910480 7115367 Mchl_3706 Methylobacterium extorquens CM4 sporulation domain-containing protein YP_002422453.1 3909062 D 440085 CDS YP_002422454.1 218531638 7115368 3910744..3911775 1 NC_011757.1 PFAM: glycoside hydrolase; KEGG: mex:Mext_3398 beta-N-acetylhexosaminidase; beta-N-acetylhexosaminidase 3911775 7115368 Mchl_3707 Methylobacterium extorquens CM4 beta-N-acetylhexosaminidase YP_002422454.1 3910744 D 440085 CDS YP_002422455.1 218531639 7115369 3912041..3912328 1 NC_011757.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 3912328 tatA 7115369 tatA Methylobacterium extorquens CM4 twin arginine translocase protein A YP_002422455.1 3912041 D 440085 CDS YP_002422456.1 218531640 7115370 3912473..3912934 1 NC_011757.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: mex:Mext_3400 twin-arginine translocation protein, TatB subunit; twin-arginine translocation protein subunit TatB 3912934 7115370 Mchl_3709 Methylobacterium extorquens CM4 twin-arginine translocation protein subunit TatB YP_002422456.1 3912473 D 440085 CDS YP_002422457.1 218531641 7115371 3912931..3913731 1 NC_011757.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: mex:Mext_3401 sec-independent protein translocase, TatC subunit; Sec-independent protein translocase subunit TatC 3913731 7115371 Mchl_3710 Methylobacterium extorquens CM4 Sec-independent protein translocase subunit TatC YP_002422457.1 3912931 D 440085 CDS YP_002422458.1 218531642 7115372 3913881..3914579 1 NC_011757.1 KEGG: mex:Mext_3402 hypothetical protein; hypothetical protein 3914579 7115372 Mchl_3711 Methylobacterium extorquens CM4 hypothetical protein YP_002422458.1 3913881 D 440085 CDS YP_002422459.1 218531643 7115373 complement(3914586..3915761) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_3403 major facilitator transporter; major facilitator superfamily protein 3915761 7115373 Mchl_3712 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422459.1 3914586 R 440085 CDS YP_002422460.1 218531644 7115374 3916171..3916740 1 NC_011757.1 PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_3404 NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 3916740 7115374 Mchl_3713 Methylobacterium extorquens CM4 NADPH-dependent FMN reductase YP_002422460.1 3916171 D 440085 CDS YP_002422461.1 218531645 7115375 3916742..3917725 1 NC_011757.1 KEGG: mex:Mext_3405 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 3917725 7115375 Mchl_3714 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002422461.1 3916742 D 440085 CDS YP_002422462.1 218531646 7115376 3917734..3918582 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3406 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 3918582 7115376 Mchl_3715 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422462.1 3917734 D 440085 CDS YP_002422463.1 218531647 7115377 3918622..3919413 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3407 ABC transporter; ABC transporter 3919413 7115377 Mchl_3716 Methylobacterium extorquens CM4 ABC transporter YP_002422463.1 3918622 D 440085 CDS YP_002422464.1 218531648 7115378 3919442..3920617 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_3408 alkanesulfonate monooxygenase; alkanesulfonate monooxygenase 3920617 7115378 Mchl_3717 Methylobacterium extorquens CM4 alkanesulfonate monooxygenase YP_002422464.1 3919442 D 440085 CDS YP_002422465.1 218531649 7115379 3920636..3921610 1 NC_011757.1 KEGG: mex:Mext_3409 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 3921610 7115379 Mchl_3718 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002422465.1 3920636 D 440085 CDS YP_002422466.1 218531650 7115380 3921712..3922674 1 NC_011757.1 KEGG: mex:Mext_3410 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein 3922674 7115380 Mchl_3719 Methylobacterium extorquens CM4 aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein YP_002422466.1 3921712 D 440085 CDS YP_002422467.1 218531651 7115381 3922709..3924091 1 NC_011757.1 KEGG: mex:Mext_3411 pyridine nucleotide-disulfide oxidoreductase family protein; pyridine nucleotide-disulfide oxidoreductase family protein 3924091 7115381 Mchl_3720 Methylobacterium extorquens CM4 pyridine nucleotide-disulfide oxidoreductase family protein YP_002422467.1 3922709 D 440085 CDS YP_002422468.1 218531652 7115382 3924427..3924636 1 NC_011757.1 KEGG: mex:Mext_3412 hypothetical protein; hypothetical protein 3924636 7115382 Mchl_3721 Methylobacterium extorquens CM4 hypothetical protein YP_002422468.1 3924427 D 440085 CDS YP_002422469.1 218531653 7115383 3924876..3925562 1 NC_011757.1 KEGG: mex:Mext_3413 hypothetical protein; hypothetical protein 3925562 7115383 Mchl_3722 Methylobacterium extorquens CM4 hypothetical protein YP_002422469.1 3924876 D 440085 CDS YP_002422470.1 218531654 7115384 complement(3925678..3926838) 1 NC_011757.1 KEGG: mex:Mext_3414 hypothetical protein; hypothetical protein 3926838 7115384 Mchl_3723 Methylobacterium extorquens CM4 hypothetical protein YP_002422470.1 3925678 R 440085 CDS YP_002422471.1 218531655 7115385 3927019..3930369 1 NC_011757.1 PFAM: transglutaminase; transglutaminase domain protein; KEGG: mex:Mext_3415 transglutaminase domain-containing protein; transglutaminase 3930369 7115385 Mchl_3724 Methylobacterium extorquens CM4 transglutaminase YP_002422471.1 3927019 D 440085 CDS YP_002422472.1 218531656 7115386 3930366..3932906 1 NC_011757.1 PFAM: protein of unknown function DUF403; protein of unknown function DUF404; protein of unknown function DUF407; KEGG: mex:Mext_3416 hypothetical protein; hypothetical protein 3932906 7115386 Mchl_3725 Methylobacterium extorquens CM4 hypothetical protein YP_002422472.1 3930366 D 440085 CDS YP_002422473.1 218531657 7115387 3932903..3933805 1 NC_011757.1 PFAM: transglutaminase; transglutaminase domain protein; KEGG: mex:Mext_3417 transglutaminase domain-containing protein; transglutaminase 3933805 7115387 Mchl_3726 Methylobacterium extorquens CM4 transglutaminase YP_002422473.1 3932903 D 440085 CDS YP_002422474.1 218531658 7115388 complement(3933819..3934373) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_3418 regulatory protein TetR; TetR family transcriptional regulator 3934373 7115388 Mchl_3727 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002422474.1 3933819 R 440085 CDS YP_002422475.1 218531659 7115389 3934569..3935309 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3419 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 3935309 7115389 Mchl_3728 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422475.1 3934569 D 440085 CDS YP_002422476.1 218531660 7115390 complement(3935349..3936734) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_3420 major facilitator transporter; major facilitator superfamily protein 3936734 7115390 Mchl_3729 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422476.1 3935349 R 440085 CDS YP_002422477.1 218531661 7115391 complement(3936845..3937432) 1 NC_011757.1 KEGG: mex:Mext_3421 hypothetical protein; hypothetical protein 3937432 7115391 Mchl_3730 Methylobacterium extorquens CM4 hypothetical protein YP_002422477.1 3936845 R 440085 CDS YP_002422478.1 218531662 7115392 3937677..3939488 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_3422 beta-lactamase; beta-lactamase 3939488 7115392 Mchl_3731 Methylobacterium extorquens CM4 beta-lactamase YP_002422478.1 3937677 D 440085 CDS YP_002422479.1 218531663 7115393 3939677..3941200 1 NC_011757.1 PFAM: aldehyde dehydrogenase; KEGG: mex:Mext_3423 aldehyde dehydrogenase; aldehyde dehydrogenase 3941200 7115393 Mchl_3732 Methylobacterium extorquens CM4 aldehyde dehydrogenase YP_002422479.1 3939677 D 440085 CDS YP_002422480.1 218531664 7115394 3941690..3943366 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_3424 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 3943366 7115394 Mchl_3733 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002422480.1 3941690 D 440085 CDS YP_002422481.1 218531665 7115395 complement(3943476..3944762) 1 NC_011757.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mex:Mext_3425 Orn/DAP/Arg decarboxylase 2; Orn/DAP/Arg decarboxylase 2 3944762 7115395 Mchl_3734 Methylobacterium extorquens CM4 Orn/DAP/Arg decarboxylase 2 YP_002422481.1 3943476 R 440085 CDS YP_002422482.1 218531666 7115396 complement(3944768..3946285) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_3426 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 3946285 7115396 Mchl_3735 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002422482.1 3944768 R 440085 CDS YP_002422483.1 218531667 7115397 complement(3946305..3946556) 1 NC_011757.1 KEGG: mex:Mext_3427 hypothetical protein; hypothetical protein 3946556 7115397 Mchl_3736 Methylobacterium extorquens CM4 hypothetical protein YP_002422483.1 3946305 R 440085 CDS YP_002422484.1 218531668 7115398 3946778..3947305 1 NC_011757.1 PFAM: DoxX family protein; KEGG: mex:Mext_3428 DoxX family protein; DoxX family protein 3947305 7115398 Mchl_3737 Methylobacterium extorquens CM4 DoxX family protein YP_002422484.1 3946778 D 440085 CDS YP_002422485.1 218531669 7115399 complement(3947262..3948743) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_3429 major facilitator transporter; major facilitator superfamily protein 3948743 7115399 Mchl_3738 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422485.1 3947262 R 440085 CDS YP_002422486.1 218531670 7115400 3949062..3949946 1 NC_011757.1 KEGG: mex:Mext_3430 hypothetical protein; hypothetical protein 3949946 7115400 Mchl_3739 Methylobacterium extorquens CM4 hypothetical protein YP_002422486.1 3949062 D 440085 CDS YP_002422487.1 218531671 7115401 complement(3950146..3951951) 1 NC_011757.1 PFAM: amidohydrolase; KEGG: mex:Mext_3431 adenine deaminase; adenine deaminase 3951951 7115401 Mchl_3740 Methylobacterium extorquens CM4 adenine deaminase YP_002422487.1 3950146 R 440085 CDS YP_002422488.1 218531672 7115402 complement(3952036..3952755) 1 NC_011757.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: mex:Mext_3432 ribosomal RNA methyltransferase RrmJ/FtsJ; ribosomal RNA methyltransferase RrmJ/FtsJ 3952755 7115402 Mchl_3741 Methylobacterium extorquens CM4 ribosomal RNA methyltransferase RrmJ/FtsJ YP_002422488.1 3952036 R 440085 CDS YP_002422489.1 218531673 7115403 complement(3952898..3954025) 1 NC_011757.1 PFAM: Ppx/GppA phosphatase; KEGG: mex:Mext_3433 Ppx/GppA phosphatase; Ppx/GppA phosphatase 3954025 7115403 Mchl_3742 Methylobacterium extorquens CM4 Ppx/GppA phosphatase YP_002422489.1 3952898 R 440085 CDS YP_002422490.1 218531674 7115404 complement(3954172..3955332) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_3434 glycosyl transferase; family 2 glycosyl transferase 3955332 7115404 Mchl_3743 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002422490.1 3954172 R 440085 CDS YP_002422491.1 218531675 7115405 complement(3955329..3956144) 1 NC_011757.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: mex:Mext_3435 phospholipid/glycerol acyltransferase; phospholipid/glycerol acyltransferase 3956144 7115405 Mchl_3744 Methylobacterium extorquens CM4 phospholipid/glycerol acyltransferase YP_002422491.1 3955329 R 440085 CDS YP_002422492.1 218531676 7115406 complement(3956155..3957693) 1 NC_011757.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_3436 phytoene desaturase; phytoene desaturase 3957693 7115406 Mchl_3745 Methylobacterium extorquens CM4 phytoene desaturase YP_002422492.1 3956155 R 440085 CDS YP_002422493.1 218531677 7115407 complement(3957792..3958652) 1 NC_011757.1 PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3437 glutamine amidotransferase class-I; class I glutamine amidotransferase 3958652 7115407 Mchl_3746 Methylobacterium extorquens CM4 class I glutamine amidotransferase YP_002422493.1 3957792 R 440085 CDS YP_002422494.1 218531678 7115408 complement(3958848..3960059) 1 NC_011757.1 PFAM: ABC transporter; KEGG: mex:Mext_3438 ABC-2 type transporter; ABC transporter 3960059 7115408 Mchl_3747 Methylobacterium extorquens CM4 ABC transporter YP_002422494.1 3958848 R 440085 CDS YP_002422495.1 218531679 7115409 complement(3960056..3961024) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3439 ABC transporter; ABC transporter 3961024 7115409 Mchl_3748 Methylobacterium extorquens CM4 ABC transporter YP_002422495.1 3960056 R 440085 CDS YP_002422496.1 218531680 7115410 complement(3961032..3961460) 1 NC_011757.1 KEGG: mex:Mext_3440 hypothetical protein; hypothetical protein 3961460 7115410 Mchl_3749 Methylobacterium extorquens CM4 hypothetical protein YP_002422496.1 3961032 R 440085 CDS YP_002422497.1 218531681 7115411 complement(3961460..3963052) 1 NC_011757.1 TIGRFAM: phytoene desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_3441 phytoene desaturase; phytoene desaturase 3963052 7115411 Mchl_3750 Methylobacterium extorquens CM4 phytoene desaturase YP_002422497.1 3961460 R 440085 CDS YP_002422498.1 218531682 7115412 complement(3963166..3964665) 1 NC_011757.1 KEGG: mex:Mext_3442 hypothetical protein; hypothetical protein 3964665 7115412 Mchl_3751 Methylobacterium extorquens CM4 hypothetical protein YP_002422498.1 3963166 R 440085 CDS YP_002422499.1 218531683 7115413 complement(3964778..3965587) 1 NC_011757.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mex:Mext_3443 tRNA/rRNA methyltransferase (SpoU); tRNA/rRNA methyltransferase SpoU 3965587 7115413 Mchl_3752 Methylobacterium extorquens CM4 tRNA/rRNA methyltransferase SpoU YP_002422499.1 3964778 R 440085 CDS YP_002422500.1 218531684 7115414 complement(3965657..3966130) 1 NC_011757.1 PFAM: MaoC domain protein dehydratase; KEGG: mex:Mext_3444 dehydratase; MaoC domain-containing protein dehydratase 3966130 7115414 Mchl_3753 Methylobacterium extorquens CM4 MaoC domain-containing protein dehydratase YP_002422500.1 3965657 R 440085 CDS YP_002422501.1 218531685 7115415 3966412..3967029 1 NC_011757.1 PFAM: cation efflux protein; KEGG: mex:Mext_3445 cation efflux protein; cation efflux protein 3967029 7115415 Mchl_3754 Methylobacterium extorquens CM4 cation efflux protein YP_002422501.1 3966412 D 440085 CDS YP_002422502.1 218531686 7115416 3967065..3967913 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_3446 metallophosphoesterase; metallophosphoesterase 3967913 7115416 Mchl_3755 Methylobacterium extorquens CM4 metallophosphoesterase YP_002422502.1 3967065 D 440085 CDS YP_002422503.1 218531687 7115417 3968006..3968227 1 NC_011757.1 KEGG: mex:Mext_3447 hypothetical protein; hypothetical protein 3968227 7115417 Mchl_3756 Methylobacterium extorquens CM4 hypothetical protein YP_002422503.1 3968006 D 440085 CDS YP_002422504.1 218531688 7115418 3968352..3969494 1 NC_011757.1 KEGG: mex:Mext_3448 hypothetical protein; hypothetical protein 3969494 7115418 Mchl_3757 Methylobacterium extorquens CM4 hypothetical protein YP_002422504.1 3968352 D 440085 CDS YP_002422505.1 218531689 7115419 3969545..3970156 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_3449 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 3970156 7115419 Mchl_3758 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002422505.1 3969545 D 440085 CDS YP_002422506.1 218531690 7115420 3970327..3970539 1 NC_011757.1 KEGG: mex:Mext_3450 hypothetical protein; hypothetical protein 3970539 7115420 Mchl_3759 Methylobacterium extorquens CM4 hypothetical protein YP_002422506.1 3970327 D 440085 CDS YP_002422507.1 218531691 7115421 complement(3970731..3971924) 1 NC_011757.1 PFAM: amidinotransferase; KEGG: mex:Mext_3451 non-specific serine/threonine protein kinase; non-specific serine/threonine protein kinase 3971924 7115421 Mchl_3760 Methylobacterium extorquens CM4 non-specific serine/threonine protein kinase YP_002422507.1 3970731 R 440085 CDS YP_002422508.1 218531692 7115422 3972136..3973269 1 NC_011757.1 TIGRFAM: membrane protein; PFAM: conserved hypothetical protein; KEGG: mex:Mext_3452 membrane protein; membrane protein 3973269 7115422 Mchl_3761 Methylobacterium extorquens CM4 membrane protein YP_002422508.1 3972136 D 440085 CDS YP_002422509.1 218531693 7115423 3973260..3973883 1 NC_011757.1 PFAM: toluene tolerance family protein; KEGG: mex:Mext_3453 toluene tolerance family protein; toluene tolerance family protein 3973883 7115423 Mchl_3762 Methylobacterium extorquens CM4 toluene tolerance family protein YP_002422509.1 3973260 D 440085 CDS YP_002422510.1 218531694 7115424 3974067..3975263 1 NC_011757.1 TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI; KEGG: mex:Mext_3454 glucosyltransferase; hopanoid biosynthesis associated glycosyl transferase protein HpnI 3975263 7115424 Mchl_3763 Methylobacterium extorquens CM4 hopanoid biosynthesis associated glycosyl transferase protein HpnI YP_002422510.1 3974067 D 440085 CDS YP_002422511.1 218531695 7115425 3975321..3976745 1 NC_011757.1 KEGG: mex:Mext_3455 hopanoid biosynthesis associated radical SAM protein HpnJ; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnJ; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; hopanoid biosynthesis associated radical SAM protein HpnJ 3976745 7115425 Mchl_3764 Methylobacterium extorquens CM4 hopanoid biosynthesis associated radical SAM protein HpnJ YP_002422511.1 3975321 D 440085 CDS YP_002422512.1 218531696 7115426 3976875..3977717 1 NC_011757.1 TIGRFAM: hopanoid biosynthesis associated protein HpnK; PFAM: YdjC family protein; KEGG: mex:Mext_3456 hopanoid biosynthesis associated protein HpnK; hopanoid biosynthesis associated protein HpnK 3977717 7115426 Mchl_3765 Methylobacterium extorquens CM4 hopanoid biosynthesis associated protein HpnK YP_002422512.1 3976875 D 440085 CDS YP_002422513.1 218531697 7115427 3977976..3978479 1 NC_011757.1 KEGG: mex:Mext_3457 hypothetical protein; hypothetical protein 3978479 7115427 Mchl_3766 Methylobacterium extorquens CM4 hypothetical protein YP_002422513.1 3977976 D 440085 CDS YP_002422514.1 218531698 7114195 complement(3978614..3981262) 1 NC_011757.1 TIGRFAM: hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: mpo:Mpop_3657 hopanoid biosynthesis associated RND transporter like protein HpnN; hopanoid biosynthesis associated RND transporter-like protein HpnN 3981262 7114195 Mchl_3767 Methylobacterium extorquens CM4 hopanoid biosynthesis associated RND transporter-like protein HpnN YP_002422514.1 3978614 R 440085 CDS YP_002422515.1 218531699 7116962 3982010..3983173 1 NC_011757.1 TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: radical SAM protein; KEGG: mex:Mext_3460 hopanoid biosynthesis associated radical SAM protein HpnH; hopanoid biosynthesis associated radical SAM protein HpnH 3983173 7116962 Mchl_3768 Methylobacterium extorquens CM4 hopanoid biosynthesis associated radical SAM protein HpnH YP_002422515.1 3982010 D 440085 CDS YP_002422516.1 218531700 7116963 complement(3983368..3984060) 1 NC_011757.1 TIGRFAM: hopanoid-associated phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: mex:Mext_3461 hypothetical protein; hopanoid-associated phosphorylase 3984060 7116963 Mchl_3769 Methylobacterium extorquens CM4 hopanoid-associated phosphorylase YP_002422516.1 3983368 R 440085 CDS YP_002422517.1 218531701 7116964 complement(3984072..3985238) 1 NC_011757.1 PFAM: polysaccharide export protein; KEGG: mex:Mext_3462 polysaccharide export protein; polysaccharide export protein 3985238 7116964 Mchl_3770 Methylobacterium extorquens CM4 polysaccharide export protein YP_002422517.1 3984072 R 440085 CDS YP_002422518.1 218531702 7116965 3985542..3986084 1 NC_011757.1 KEGG: mex:Mext_3463 carbohydrate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; thermoresistant glucokinase family carbohydrate kinase 3986084 7116965 Mchl_3771 Methylobacterium extorquens CM4 thermoresistant glucokinase family carbohydrate kinase YP_002422518.1 3985542 D 440085 CDS YP_002422519.1 218531703 7116966 3986093..3986896 1 NC_011757.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: mex:Mext_3464 Cof-like hydrolase; Cof-like hydrolase 3986896 7116966 Mchl_3772 Methylobacterium extorquens CM4 Cof-like hydrolase YP_002422519.1 3986093 D 440085 CDS YP_002422520.1 218531704 7116967 3987144..3988037 1 NC_011757.1 PFAM: lytic transglycosylase catalytic; KEGG: mex:Mext_3465 lytic transglycosylase catalytic; lytic transglycosylase 3988037 7116967 Mchl_3773 Methylobacterium extorquens CM4 lytic transglycosylase YP_002422520.1 3987144 D 440085 CDS YP_002422521.1 218531705 7116968 3988195..3988383 1 NC_011757.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 3988383 rpmF 7116968 rpmF Methylobacterium extorquens CM4 50S ribosomal protein L32 YP_002422521.1 3988195 D 440085 CDS YP_002422522.1 218531706 7116969 complement(3988466..3988714) 1 NC_011757.1 KEGG: mex:Mext_3467 hypothetical protein; hypothetical protein 3988714 7116969 Mchl_3775 Methylobacterium extorquens CM4 hypothetical protein YP_002422522.1 3988466 R 440085 CDS YP_002422523.1 218531707 7116970 complement(3988936..3989547) 1 NC_011757.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein; KEGG: mex:Mext_3468 polyhydroxyalkanoate synthesis repressor PhaR; polyhydroxyalkonate synthesis repressor, PhaR 3989547 7116970 Mchl_3776 Methylobacterium extorquens CM4 polyhydroxyalkonate synthesis repressor, PhaR YP_002422523.1 3988936 R 440085 CDS YP_002422524.1 218531708 7116971 3989873..3991057 1 NC_011757.1 KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase; acetyl-CoA acetyltransferase 3991057 7116971 Mchl_3777 Methylobacterium extorquens CM4 acetyl-CoA acetyltransferase YP_002422524.1 3989873 D 440085 CDS YP_002422525.1 218531709 7116972 3991330..3992058 1 NC_011757.1 TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3470 acetoacetyl-CoA reductase; acetoacetyl-CoA reductase 3992058 7116972 Mchl_3778 Methylobacterium extorquens CM4 acetoacetyl-CoA reductase YP_002422525.1 3991330 D 440085 CDS YP_002422526.1 218531710 7116973 3992214..3993188 1 NC_011757.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 3993188 7116973 Mchl_3779 Methylobacterium extorquens CM4 lipid A biosynthesis lauroyl acyltransferase YP_002422526.1 3992214 D 440085 CDS YP_002422527.1 218531711 7116974 complement(3993217..3994476) 1 NC_011757.1 PFAM: peptidase M29 aminopeptidase II; KEGG: mex:Mext_3472 peptidase M29 aminopeptidase II; peptidase M29 aminopeptidase II 3994476 7116974 Mchl_3780 Methylobacterium extorquens CM4 peptidase M29 aminopeptidase II YP_002422527.1 3993217 R 440085 CDS YP_002422528.1 218531712 7116975 complement(3994554..3994847) 1 NC_011757.1 KEGG: mex:Mext_3473 hypothetical protein; hypothetical protein 3994847 7116975 Mchl_3781 Methylobacterium extorquens CM4 hypothetical protein YP_002422528.1 3994554 R 440085 CDS YP_002422529.1 218531713 7116976 complement(3995225..3996676) 1 NC_011757.1 PFAM: FAD linked oxidase; KEGG: mex:Mext_3474 FAD linked oxidase domain-containing protein; FAD linked oxidase 3996676 7116976 Mchl_3782 Methylobacterium extorquens CM4 FAD linked oxidase YP_002422529.1 3995225 R 440085 CDS YP_002422530.1 218531714 7116977 3996884..3997579 1 NC_011757.1 PFAM: fumarylacetoacetate hydrolase; KEGG: mex:Mext_3475 fumarylacetoacetate hydrolase; fumarylacetoacetate hydrolase 3997579 7116977 Mchl_3783 Methylobacterium extorquens CM4 fumarylacetoacetate hydrolase YP_002422530.1 3996884 D 440085 CDS YP_002422531.1 218531715 7116978 3997627..3998103 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_3476 NUDIX hydrolase; NUDIX hydrolase 3998103 7116978 Mchl_3784 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002422531.1 3997627 D 440085 CDS YP_002422532.1 218531716 7116980 3998556..3999833 1 NC_011757.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: mex:Mext_3477 DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 3999833 7116980 Mchl_3785 Methylobacterium extorquens CM4 DegT/DnrJ/EryC1/StrS aminotransferase YP_002422532.1 3998556 D 440085 CDS YP_002422533.1 218531717 7116981 complement(3999989..4000717) 1 NC_011757.1 PFAM: Resolvase domain; KEGG: mex:Mext_3478 resolvase domain-containing protein; Resolvase domain 4000717 7116981 Mchl_3786 Methylobacterium extorquens CM4 Resolvase domain YP_002422533.1 3999989 R 440085 CDS YP_002422534.1 218531718 7116982 4000832..4001908 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3479 regulatory protein LysR; LysR family transcriptional regulator 4001908 7116982 Mchl_3787 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422534.1 4000832 D 440085 CDS YP_002422535.1 218531719 7116983 4002302..4003051 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_3480 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 4003051 7116983 Mchl_3788 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422535.1 4002302 D 440085 CDS YP_002422536.1 218531720 7116984 complement(4003234..4003512) 1 NC_011757.1 KEGG: mex:Mext_3481 hypothetical protein; hypothetical protein 4003512 7116984 Mchl_3789 Methylobacterium extorquens CM4 hypothetical protein YP_002422536.1 4003234 R 440085 CDS YP_002422537.1 218531721 7116985 4003832..4004095 1 NC_011757.1 KEGG: mex:Mext_3482 hypothetical protein; hypothetical protein 4004095 7116985 Mchl_3790 Methylobacterium extorquens CM4 hypothetical protein YP_002422537.1 4003832 D 440085 CDS YP_002422538.1 218531722 7116986 4004226..4004648 1 NC_011757.1 KEGG: mex:Mext_3483 hypothetical protein; hypothetical protein 4004648 7116986 Mchl_3791 Methylobacterium extorquens CM4 hypothetical protein YP_002422538.1 4004226 D 440085 CDS YP_002422539.1 218531723 7116987 complement(4004749..4005825) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_3484 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 4005825 7116987 Mchl_3792 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase type 2 domain-containing protein YP_002422539.1 4004749 R 440085 CDS YP_002422540.1 218531724 7116988 complement(4005831..4006388) 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_3485 OsmC family protein; OsmC family protein 4006388 7116988 Mchl_3793 Methylobacterium extorquens CM4 OsmC family protein YP_002422540.1 4005831 R 440085 CDS YP_002422541.1 218531725 7116989 complement(4006400..4007257) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3486 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4007257 7116989 Mchl_3794 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422541.1 4006400 R 440085 CDS YP_002422542.1 218531726 7116990 complement(4007254..4008480) 1 NC_011757.1 KEGG: mex:Mext_3487 twin-arginine translocation pathway signal; twin-arginine translocation pathway signal 4008480 7116990 Mchl_3795 Methylobacterium extorquens CM4 twin-arginine translocation pathway signal YP_002422542.1 4007254 R 440085 CDS YP_002422543.1 218531727 7116991 complement(4008503..4009258) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3488 ABC transporter; ABC transporter 4009258 7116991 Mchl_3796 Methylobacterium extorquens CM4 ABC transporter YP_002422543.1 4008503 R 440085 CDS YP_002422544.1 218531728 7116992 4009930..4011384 1 NC_011757.1 PFAM: carbohydrate-selective porin OprB; KEGG: mex:Mext_3489 carbohydrate-selective porin OprB; carbohydrate-selective porin OprB 4011384 7116992 Mchl_3797 Methylobacterium extorquens CM4 carbohydrate-selective porin OprB YP_002422544.1 4009930 D 440085 CDS YP_002422545.1 218531729 7116993 4011439..4012842 1 NC_011757.1 KEGG: mex:Mext_3490 monooxygenase; monooxygenase 4012842 7116993 Mchl_3798 Methylobacterium extorquens CM4 monooxygenase YP_002422545.1 4011439 D 440085 CDS YP_002422546.1 218531730 7116994 4012848..4013618 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3491 ABC transporter; ABC transporter 4013618 7116994 Mchl_3799 Methylobacterium extorquens CM4 ABC transporter YP_002422546.1 4012848 D 440085 CDS YP_002422547.1 218531731 7116995 4013629..4014510 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_3492 inner-membrane translocator; inner-membrane translocator 4014510 7116995 Mchl_3800 Methylobacterium extorquens CM4 inner-membrane translocator YP_002422547.1 4013629 D 440085 CDS YP_002422548.1 218531732 7116996 4014515..4015558 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_3493 inner-membrane translocator; inner-membrane translocator 4015558 7116996 Mchl_3801 Methylobacterium extorquens CM4 inner-membrane translocator YP_002422548.1 4014515 D 440085 CDS YP_002422549.1 218531733 7116997 4015593..4016966 1 NC_011757.1 KEGG: mex:Mext_3494 hypothetical protein; hypothetical protein 4016966 7116997 Mchl_3802 Methylobacterium extorquens CM4 hypothetical protein YP_002422549.1 4015593 D 440085 CDS YP_002422550.1 218531734 7116998 4016963..4017724 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3495 ABC transporter; ABC transporter 4017724 7116998 Mchl_3803 Methylobacterium extorquens CM4 ABC transporter YP_002422550.1 4016963 D 440085 CDS YP_002422551.1 218531735 7116999 4017756..4019018 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_3496 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 4019018 7116999 Mchl_3804 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase type 2 domain-containing protein YP_002422551.1 4017756 D 440085 CDS YP_002422552.1 218531736 7117000 4019659..4020135 1 NC_011757.1 PFAM: heat shock protein Hsp20; KEGG: mex:Mext_3498 heat shock protein HSP20; heat shock protein Hsp20 4020135 7117000 Mchl_3805 Methylobacterium extorquens CM4 heat shock protein Hsp20 YP_002422552.1 4019659 D 440085 CDS YP_002422553.1 218531737 7117002 4021094..4021906 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_3500 UspA domain-containing protein; UspA domain-containing protein 4021906 7117002 Mchl_3807 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002422553.1 4021094 D 440085 CDS YP_002422554.1 218531738 7117003 4022051..4022500 1 NC_011757.1 KEGG: mex:Mext_3501 hypothetical protein; hypothetical protein 4022500 7117003 Mchl_3808 Methylobacterium extorquens CM4 hypothetical protein YP_002422554.1 4022051 D 440085 CDS YP_002422555.1 218531739 7117004 complement(4022531..4022857) 1 NC_011757.1 PFAM: transport-associated; KEGG: mex:Mext_3502 transport-associated; transport-associated 4022857 7117004 Mchl_3809 Methylobacterium extorquens CM4 transport-associated YP_002422555.1 4022531 R 440085 CDS YP_002422556.1 218531740 7117005 complement(4022890..4023111) 1 NC_011757.1 KEGG: mex:Mext_3503 hypothetical protein; hypothetical protein 4023111 7117005 Mchl_3810 Methylobacterium extorquens CM4 hypothetical protein YP_002422556.1 4022890 R 440085 CDS YP_002422557.1 218531741 7117006 4023376..4024236 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_3504 UspA domain-containing protein; UspA domain-containing protein 4024236 7117006 Mchl_3811 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002422557.1 4023376 D 440085 CDS YP_002422558.1 218531742 7117007 complement(4024354..4025043) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_3505 regulatory protein Crp; Crp/Fnr family transcriptional regulator 4025043 7117007 Mchl_3812 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422558.1 4024354 R 440085 CDS YP_002422559.1 218531743 7117008 complement(4025580..4026188) 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: mex:Mext_3506 response regulator receiver; LuxR family transcriptional regulator 4026188 7117008 Mchl_3813 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002422559.1 4025580 R 440085 CDS YP_002422560.1 218531744 7117009 complement(4026192..4027739) 1 NC_011757.1 KEGG: mex:Mext_3507 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor signal transduction histidine kinase 4027739 7117009 Mchl_3814 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002422560.1 4026192 R 440085 CDS YP_002422561.1 218531745 7117010 4028082..4028942 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_3508 UspA domain-containing protein; UspA domain-containing protein 4028942 7117010 Mchl_3815 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002422561.1 4028082 D 440085 CDS YP_002422562.1 218531746 7117011 4029160..4030215 1 NC_011757.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_3509 metal-dependent phosphohydrolase; response regulator receiver modulated metal dependent phosphohydrolase 4030215 7117011 Mchl_3816 Methylobacterium extorquens CM4 response regulator receiver modulated metal dependent phosphohydrolase YP_002422562.1 4029160 D 440085 CDS YP_002422563.1 218531747 7117012 complement(4030346..4033075) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: mex:Mext_3510 ATPase domain-containing protein; Hpt sensor hybrid histidine kinase 4033075 7117012 Mchl_3817 Methylobacterium extorquens CM4 Hpt sensor hybrid histidine kinase YP_002422563.1 4030346 R 440085 CDS YP_002422564.1 218531748 7117013 complement(4033244..4034665) 1 NC_011757.1 KEGG: mex:Mext_3511 hypothetical protein; hypothetical protein 4034665 7117013 Mchl_3818 Methylobacterium extorquens CM4 hypothetical protein YP_002422564.1 4033244 R 440085 CDS YP_002422565.1 218531749 7117014 complement(4034864..4035472) 1 NC_011757.1 PFAM: TadE family protein; KEGG: mex:Mext_3512 TadE family protein; TadE family protein 4035472 7117014 Mchl_3819 Methylobacterium extorquens CM4 TadE family protein YP_002422565.1 4034864 R 440085 CDS YP_002422566.1 218531750 7117015 complement(4035469..4036062) 1 NC_011757.1 PFAM: TadE family protein; KEGG: mex:Mext_3513 TadE family protein; TadE family protein 4036062 7117015 Mchl_3820 Methylobacterium extorquens CM4 TadE family protein YP_002422566.1 4035469 R 440085 CDS YP_002422567.1 218531751 7117017 4037920..4038186 1 NC_011757.1 KEGG: mpo:Mpop_4259 hypothetical protein; hypothetical protein 4038186 7117017 Mchl_3822 Methylobacterium extorquens CM4 hypothetical protein YP_002422567.1 4037920 D 440085 CDS YP_002422568.1 218531752 7117018 4038224..4038901 1 NC_011757.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: gox:GOX1539 acetyltransferase; transferase 4038901 7117018 Mchl_3823 Methylobacterium extorquens CM4 transferase YP_002422568.1 4038224 D 440085 CDS YP_002422569.1 218531753 7117020 complement(4040537..4041169) 1 NC_011757.1 PFAM: adenylylsulfate kinase; KEGG: mrd:Mrad2831_1882 adenylyl-sulfate kinase; adenylyl-sulfate kinase 4041169 7117020 Mchl_3825 Methylobacterium extorquens CM4 adenylyl-sulfate kinase YP_002422569.1 4040537 R 440085 CDS YP_002422570.1 218531754 7117021 4041722..4041934 1 NC_011757.1 KEGG: mex:Mext_0808 hypothetical protein; hypothetical protein 4041934 7117021 Mchl_3826 Methylobacterium extorquens CM4 hypothetical protein YP_002422570.1 4041722 D 440085 CDS YP_002422571.1 218531755 7117022 complement(4041965..4042246) 1 NC_011757.1 KEGG: mex:Mext_0807 hypothetical protein; hypothetical protein 4042246 7117022 Mchl_3827 Methylobacterium extorquens CM4 hypothetical protein YP_002422571.1 4041965 R 440085 CDS YP_002422572.1 218531756 7117023 complement(4042611..4042754) 1 NC_011757.1 KEGG: mpo:Mpop_3761 hypothetical protein; hypothetical protein 4042754 7117023 Mchl_3828 Methylobacterium extorquens CM4 hypothetical protein YP_002422572.1 4042611 R 440085 CDS YP_002422573.1 218531757 7117024 complement(4042870..4043334) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_4463 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 4043334 7117024 Mchl_3829 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002422573.1 4042870 R 440085 CDS YP_002422574.1 218531758 7117025 complement(4043636..4044094) 1 NC_011757.1 hypothetical protein 4044094 7117025 Mchl_3830 Methylobacterium extorquens CM4 hypothetical protein YP_002422574.1 4043636 R 440085 CDS YP_002422575.1 218531759 7117026 complement(4044091..4044552) 1 NC_011757.1 hypothetical protein 4044552 7117026 Mchl_3831 Methylobacterium extorquens CM4 hypothetical protein YP_002422575.1 4044091 R 440085 CDS YP_002422576.1 218531760 7117027 complement(4044566..4044877) 1 NC_011757.1 KEGG: mex:Mext_4382 hypothetical protein; hypothetical protein 4044877 7117027 Mchl_3832 Methylobacterium extorquens CM4 hypothetical protein YP_002422576.1 4044566 R 440085 CDS YP_002422577.1 218531761 7117028 complement(4044874..4045305) 1 NC_011757.1 KEGG: mex:Mext_4382 hypothetical protein; hypothetical protein 4045305 7117028 Mchl_3833 Methylobacterium extorquens CM4 hypothetical protein YP_002422577.1 4044874 R 440085 CDS YP_002422578.1 218531762 7117029 complement(4045503..4046204) 1 NC_011757.1 PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_4383 peptidoglycan binding domain-containing protein; peptidoglycan-binding protein 4046204 7117029 Mchl_3834 Methylobacterium extorquens CM4 peptidoglycan-binding protein YP_002422578.1 4045503 R 440085 CDS YP_002422579.1 218531763 7117030 complement(4046698..4046994) 1 NC_011757.1 hypothetical protein 4046994 7117030 Mchl_3835 Methylobacterium extorquens CM4 hypothetical protein YP_002422579.1 4046698 R 440085 CDS YP_002422580.1 218531764 7117031 complement(4047005..4047589) 1 NC_011757.1 KEGG: azc:AZC_2161 hypothetical protein; hypothetical protein 4047589 7117031 Mchl_3836 Methylobacterium extorquens CM4 hypothetical protein YP_002422580.1 4047005 R 440085 CDS YP_002422581.1 218531765 7117032 complement(4047595..4048920) 1 NC_011757.1 KEGG: mrd:Mrad2831_4981 hypothetical protein; hypothetical protein 4048920 7117032 Mchl_3837 Methylobacterium extorquens CM4 hypothetical protein YP_002422581.1 4047595 R 440085 CDS YP_002422582.1 218531766 7117033 complement(4049497..4049832) 1 NC_011757.1 hypothetical protein 4049832 7117033 Mchl_3838 Methylobacterium extorquens CM4 hypothetical protein YP_002422582.1 4049497 R 440085 CDS YP_002422583.1 218531767 7117037 4051672..4051938 1 NC_011757.1 KEGG: mpo:Mpop_4259 hypothetical protein; hypothetical protein 4051938 7117037 Mchl_3841 Methylobacterium extorquens CM4 hypothetical protein YP_002422583.1 4051672 D 440085 CDS YP_002422584.1 218531768 7117038 4051963..4052847 1 NC_011757.1 KEGG: azc:AZC_0734 hypothetical protein; hypothetical protein 4052847 7117038 Mchl_3842 Methylobacterium extorquens CM4 hypothetical protein YP_002422584.1 4051963 D 440085 CDS YP_002422585.1 218531769 7117041 4053763..4054830 1 NC_011757.1 KEGG: mrd:Mrad2831_5645 hypothetical protein; hypothetical protein 4054830 7117041 Mchl_3845 Methylobacterium extorquens CM4 hypothetical protein YP_002422585.1 4053763 D 440085 CDS YP_002422586.1 218531770 7117042 4054988..4055200 1 NC_011757.1 KEGG: mpo:Mpop_3765 hypothetical protein; hypothetical protein 4055200 7117042 Mchl_3846 Methylobacterium extorquens CM4 hypothetical protein YP_002422586.1 4054988 D 440085 CDS YP_002422587.1 218531771 7114855 4055205..4055402 1 NC_011757.1 KEGG: mpo:Mpop_4256 hypothetical protein; hypothetical protein 4055402 7114855 Mchl_3847 Methylobacterium extorquens CM4 hypothetical protein YP_002422587.1 4055205 D 440085 CDS YP_002422588.1 218531772 7114857 4055559..4056362 1 NC_011757.1 PFAM: ABC transporter; KEGG: mpo:Mpop_2382 ABC-2 type transporter; ABC transporter 4056362 7114857 Mchl_3848 Methylobacterium extorquens CM4 ABC transporter YP_002422588.1 4055559 D 440085 CDS YP_002422589.1 218531773 7114858 complement(4056626..4058155) 1 NC_011757.1 KEGG: met:M446_0253 capsular polysaccharide biosynthesis protein-like protein; hypothetical protein 4058155 7114858 Mchl_3849 Methylobacterium extorquens CM4 hypothetical protein YP_002422589.1 4056626 R 440085 CDS YP_002422590.1 218531774 7114859 complement(4058196..4058336) 1 NC_011757.1 hypothetical protein 4058336 7114859 Mchl_3850 Methylobacterium extorquens CM4 hypothetical protein YP_002422590.1 4058196 R 440085 CDS YP_002422591.1 218531775 7114860 complement(4058764..4059972) 1 NC_011757.1 KEGG: mpo:Mpop_4886 hypothetical protein; hypothetical protein 4059972 7114860 Mchl_3851 Methylobacterium extorquens CM4 hypothetical protein YP_002422591.1 4058764 R 440085 CDS YP_002422592.1 218531776 7114861 complement(4060264..4060620) 1 NC_011757.1 KEGG: mrd:Mrad2831_5670 hypothetical protein; hypothetical protein 4060620 7114861 Mchl_3852 Methylobacterium extorquens CM4 hypothetical protein YP_002422592.1 4060264 R 440085 CDS YP_002422593.1 218531777 7114862 complement(4060625..4061041) 1 NC_011757.1 KEGG: mrd:Mrad2831_5671 hypothetical protein; hypothetical protein 4061041 7114862 Mchl_3853 Methylobacterium extorquens CM4 hypothetical protein YP_002422593.1 4060625 R 440085 CDS YP_002422594.1 218531778 7114863 complement(4061038..4061304) 1 NC_011757.1 KEGG: mrd:Mrad2831_5672 hypothetical protein; hypothetical protein 4061304 7114863 Mchl_3854 Methylobacterium extorquens CM4 hypothetical protein YP_002422594.1 4061038 R 440085 CDS YP_002422595.1 218531779 7114864 complement(4061307..4062140) 1 NC_011757.1 KEGG: eli:ELI_07940 bacteriophage-acquired protein; hypothetical protein 4062140 7114864 Mchl_3855 Methylobacterium extorquens CM4 hypothetical protein YP_002422595.1 4061307 R 440085 CDS YP_002422596.1 218531780 7114865 4062473..4063603 1 NC_011757.1 KEGG: mpo:Mpop_4404 capsular polysaccharide biosynthesis protein-like protein; capsular polysaccharide biosynthesis protein-like protein 4063603 7114865 Mchl_3856 Methylobacterium extorquens CM4 capsular polysaccharide biosynthesis protein-like protein YP_002422596.1 4062473 D 440085 CDS YP_002422597.1 218531781 7114866 complement(4063665..4063955) 1 NC_011757.1 PFAM: Rare lipoprotein A; KEGG: cyt:cce_3687 hypothetical protein; Rare lipoprotein A 4063955 7114866 Mchl_3857 Methylobacterium extorquens CM4 Rare lipoprotein A YP_002422597.1 4063665 R 440085 CDS YP_002422598.1 218531782 7114867 complement(4064039..4065484) 1 NC_011757.1 KEGG: mlo:mll4444 hypothetical protein; hypothetical protein 4065484 7114867 Mchl_3858 Methylobacterium extorquens CM4 hypothetical protein YP_002422598.1 4064039 R 440085 CDS YP_002422599.1 218531783 7114868 complement(4065481..4065774) 1 NC_011757.1 hypothetical protein 4065774 7114868 Mchl_3859 Methylobacterium extorquens CM4 hypothetical protein YP_002422599.1 4065481 R 440085 CDS YP_002422600.1 218531784 7114869 complement(4065869..4067128) 1 NC_011757.1 KEGG: swi:Swit_4452 hypothetical protein; hypothetical protein 4067128 7114869 Mchl_3860 Methylobacterium extorquens CM4 hypothetical protein YP_002422600.1 4065869 R 440085 CDS YP_002422601.1 218531785 7114870 complement(4067141..4068007) 1 NC_011757.1 KEGG: mca:MCA1228 TolA protein; hypothetical protein 4068007 7114870 Mchl_3861 Methylobacterium extorquens CM4 hypothetical protein YP_002422601.1 4067141 R 440085 CDS YP_002422602.1 218531786 7114871 complement(4068149..4068460) 1 NC_011757.1 hypothetical protein 4068460 7114871 Mchl_3862 Methylobacterium extorquens CM4 hypothetical protein YP_002422602.1 4068149 R 440085 CDS YP_002422603.1 218531787 7114872 complement(4068560..4069057) 1 NC_011757.1 hypothetical protein 4069057 7114872 Mchl_3863 Methylobacterium extorquens CM4 hypothetical protein YP_002422603.1 4068560 R 440085 CDS YP_002422604.1 218531788 7114873 complement(4069060..4069377) 1 NC_011757.1 KEGG: nar:Saro_3000 hypothetical protein; hypothetical protein 4069377 7114873 Mchl_3864 Methylobacterium extorquens CM4 hypothetical protein YP_002422604.1 4069060 R 440085 CDS YP_002422605.1 218531789 7114874 complement(4069377..4070162) 1 NC_011757.1 KEGG: bvi:Bcep1808_1171 hypothetical protein; hypothetical protein 4070162 7114874 Mchl_3865 Methylobacterium extorquens CM4 hypothetical protein YP_002422605.1 4069377 R 440085 CDS YP_002422606.1 218531790 7114875 4070199..4070441 1 NC_011757.1 KEGG: mpo:Mpop_2745 hypothetical protein; hypothetical protein 4070441 7114875 Mchl_3866 Methylobacterium extorquens CM4 hypothetical protein YP_002422606.1 4070199 D 440085 CDS YP_002422607.1 218531791 7114876 4070441..4070734 1 NC_011757.1 hypothetical protein 4070734 7114876 Mchl_3867 Methylobacterium extorquens CM4 hypothetical protein YP_002422607.1 4070441 D 440085 CDS YP_002422608.1 218531792 7114877 4070731..4070970 1 NC_011757.1 KEGG: met:M446_4072 hypothetical protein; hypothetical protein 4070970 7114877 Mchl_3868 Methylobacterium extorquens CM4 hypothetical protein YP_002422608.1 4070731 D 440085 CDS YP_002422609.1 218531793 7114878 4071240..4072385 1 NC_011757.1 PFAM: integrase family protein; KEGG: nha:Nham_3311 phage integrase; integrase family protein 4072385 7114878 Mchl_3869 Methylobacterium extorquens CM4 integrase family protein YP_002422609.1 4071240 D 440085 CDS YP_002422610.1 218531794 7114879 4072809..4073204 1 NC_011757.1 KEGG: mex:Mext_3583 hypothetical protein; hypothetical protein 4073204 7114879 Mchl_3870 Methylobacterium extorquens CM4 hypothetical protein YP_002422610.1 4072809 D 440085 CDS YP_002422611.1 218531795 7114880 complement(4073370..4073525) 1 NC_011757.1 hypothetical protein 4073525 7114880 Mchl_3871 Methylobacterium extorquens CM4 hypothetical protein YP_002422611.1 4073370 R 440085 CDS YP_002422612.1 218531796 7114881 complement(4073763..4073864) 1 NC_011757.1 hypothetical protein 4073864 7114881 Mchl_3872 Methylobacterium extorquens CM4 hypothetical protein YP_002422612.1 4073763 R 440085 CDS YP_002422613.1 218531797 7114882 4074013..4074231 1 NC_011757.1 KEGG: mpo:Mpop_1569 hypothetical protein; hypothetical protein 4074231 7114882 Mchl_3873 Methylobacterium extorquens CM4 hypothetical protein YP_002422613.1 4074013 D 440085 CDS YP_002422614.1 218531798 7114883 4074228..4074551 1 NC_011757.1 KEGG: mex:Mext_3584 hypothetical protein; hypothetical protein 4074551 7114883 Mchl_3874 Methylobacterium extorquens CM4 hypothetical protein YP_002422614.1 4074228 D 440085 CDS YP_002422615.1 218531799 7114884 complement(4074646..4075707) 1 NC_011757.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: mex:Mext_3585 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 4075707 7114884 Mchl_3875 Methylobacterium extorquens CM4 endonuclease/exonuclease/phosphatase YP_002422615.1 4074646 R 440085 CDS YP_002422616.1 218531800 7114885 complement(4075837..4076490) 1 NC_011757.1 PFAM: protein of unknown function DUF159; KEGG: mex:Mext_3586 hypothetical protein; hypothetical protein 4076490 7114885 Mchl_3876 Methylobacterium extorquens CM4 hypothetical protein YP_002422616.1 4075837 R 440085 CDS YP_002422617.1 218531801 7114886 complement(4076637..4077353) 1 NC_011757.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_3587 ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 4077353 7114886 Mchl_3877 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002422617.1 4076637 R 440085 CDS YP_002422618.1 218531802 7114887 4077736..4078098 1 NC_011757.1 KEGG: mex:Mext_3588 hypothetical protein; hypothetical protein 4078098 7114887 Mchl_3878 Methylobacterium extorquens CM4 hypothetical protein YP_002422618.1 4077736 D 440085 CDS YP_002422619.1 218531803 7114888 4078233..4078484 1 NC_011757.1 KEGG: mex:Mext_3589 hypothetical protein; hypothetical protein 4078484 7114888 Mchl_3879 Methylobacterium extorquens CM4 hypothetical protein YP_002422619.1 4078233 D 440085 CDS YP_002422620.1 218531804 7114889 4079236..4079475 1 NC_011757.1 KEGG: mex:Mext_3590 hypothetical protein; hypothetical protein 4079475 7114889 Mchl_3880 Methylobacterium extorquens CM4 hypothetical protein YP_002422620.1 4079236 D 440085 CDS YP_002422621.1 218531805 7114890 4079775..4080230 1 NC_011757.1 KEGG: mex:Mext_3591 hypothetical protein; hypothetical protein 4080230 7114890 Mchl_3881 Methylobacterium extorquens CM4 hypothetical protein YP_002422621.1 4079775 D 440085 CDS YP_002422622.1 218531806 7114891 4080319..4080528 1 NC_011757.1 KEGG: mpo:Mpop_4880 hypothetical protein; hypothetical protein 4080528 7114891 Mchl_3882 Methylobacterium extorquens CM4 hypothetical protein YP_002422622.1 4080319 D 440085 CDS YP_002422623.1 218531807 7114892 4080682..4080981 1 NC_011757.1 KEGG: mex:Mext_3592 hypothetical protein; hypothetical protein 4080981 7114892 Mchl_3883 Methylobacterium extorquens CM4 hypothetical protein YP_002422623.1 4080682 D 440085 CDS YP_002422624.1 218531808 7114893 complement(4081149..4081340) 1 NC_011757.1 KEGG: mex:Mext_3593 hypothetical protein; hypothetical protein 4081340 7114893 Mchl_3884 Methylobacterium extorquens CM4 hypothetical protein YP_002422624.1 4081149 R 440085 CDS YP_002422625.1 218531809 7114894 4081475..4081720 1 NC_011757.1 KEGG: mex:Mext_3594 hypothetical protein; hypothetical protein 4081720 7114894 Mchl_3885 Methylobacterium extorquens CM4 hypothetical protein YP_002422625.1 4081475 D 440085 CDS YP_002422626.1 218531810 7114895 complement(4081772..4081975) 1 NC_011757.1 KEGG: mpo:Mpop_4270 hypothetical protein; hypothetical protein 4081975 7114895 Mchl_3886 Methylobacterium extorquens CM4 hypothetical protein YP_002422626.1 4081772 R 440085 CDS YP_002422627.1 218531811 7114896 complement(4082077..4082385) 1 NC_011757.1 KEGG: mex:Mext_3595 hypothetical protein; hypothetical protein 4082385 7114896 Mchl_3887 Methylobacterium extorquens CM4 hypothetical protein YP_002422627.1 4082077 R 440085 CDS YP_002422628.1 218531812 7114897 complement(4082454..4082954) 1 NC_011757.1 transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 4082954 7114897 Mchl_3888 Methylobacterium extorquens CM4 manganese transport regulator MntR YP_002422628.1 4082454 R 440085 CDS YP_002422629.1 218531813 7114898 4083337..4084671 1 NC_011757.1 TIGRFAM: Mn2+/Fe2+ transporter NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: mex:Mext_3597 Mn2+/Fe2+ transporter; NRAMP family Mn2+/Fe2+ transporter 4084671 7114898 Mchl_3889 Methylobacterium extorquens CM4 NRAMP family Mn2+/Fe2+ transporter YP_002422629.1 4083337 D 440085 CDS YP_002422630.1 218531814 7114899 complement(4084684..4085574) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3598 LysR substrate-binding; LysR family transcriptional regulator 4085574 7114899 Mchl_3890 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422630.1 4084684 R 440085 CDS YP_002422631.1 218531815 7114900 4085752..4087077 1 NC_011757.1 PFAM: sodium/sulfate symporter; citrate transporter; KEGG: mex:Mext_3599 sodium/sulfate symporter; sodium/sulfate symporter 4087077 7114900 Mchl_3891 Methylobacterium extorquens CM4 sodium/sulfate symporter YP_002422631.1 4085752 D 440085 CDS YP_002422632.1 218531816 7114901 4087205..4087606 1 NC_011757.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mex:Mext_3600 succinate dehydrogenase, cytochrome b556 subunit; succinate dehydrogenase, cytochrome b556 subunit 4087606 7114901 Mchl_3892 Methylobacterium extorquens CM4 succinate dehydrogenase, cytochrome b556 subunit YP_002422632.1 4087205 D 440085 CDS YP_002422633.1 218531817 7114902 4087615..4088034 1 NC_011757.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mpo:Mpop_4277 succinate dehydrogenase, hydrophobic membrane anchor protein; succinate dehydrogenase, hydrophobic membrane anchor protein 4088034 7114902 Mchl_3893 Methylobacterium extorquens CM4 succinate dehydrogenase, hydrophobic membrane anchor protein YP_002422633.1 4087615 D 440085 CDS YP_002422634.1 218531818 7114903 4088064..4089881 1 NC_011757.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 4089881 sdhA 7114903 sdhA Methylobacterium extorquens CM4 succinate dehydrogenase flavoprotein subunit YP_002422634.1 4088064 D 440085 CDS YP_002422635.1 218531819 7114904 4089926..4090486 1 NC_011757.1 KEGG: mex:Mext_3603 hypothetical protein; hypothetical protein 4090486 7114904 Mchl_3895 Methylobacterium extorquens CM4 hypothetical protein YP_002422635.1 4089926 D 440085 CDS YP_002422636.1 218531820 7114905 4090543..4091367 1 NC_011757.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mex:Mext_3604 succinate dehydrogenase and fumarate reductase iron-sulfur protein; succinate dehydrogenase and fumarate reductase iron-sulfur protein 4091367 7114905 Mchl_3896 Methylobacterium extorquens CM4 succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_002422636.1 4090543 D 440085 CDS YP_002422637.1 218531821 7114906 4091611..4092171 1 NC_011757.1 KEGG: mex:Mext_3605 outer membrane lipoprotein omp19; outer membrane lipoprotein omp19 4092171 7114906 Mchl_3897 Methylobacterium extorquens CM4 outer membrane lipoprotein omp19 YP_002422637.1 4091611 D 440085 CDS YP_002422638.1 218531822 7114907 complement(4092287..4094230) 1 NC_011757.1 KEGG: mex:Mext_3606 hypothetical protein; hypothetical protein 4094230 7114907 Mchl_3898 Methylobacterium extorquens CM4 hypothetical protein YP_002422638.1 4092287 R 440085 CDS YP_002422639.1 218531823 7114908 4094313..4095335 1 NC_011757.1 KEGG: mex:Mext_3607 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KpsF/GutQ family protein 4095335 7114908 Mchl_3899 Methylobacterium extorquens CM4 KpsF/GutQ family protein YP_002422639.1 4094313 D 440085 CDS YP_002422640.1 218531824 7114909 4097389..4098561 1 NC_011757.1 hypothetical protein 4098561 7114909 Mchl_3900 Methylobacterium extorquens CM4 hypothetical protein YP_002422640.1 4097389 D 440085 CDS YP_002422641.1 218531825 7114910 complement(4098659..4099102) 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_3609 hypothetical protein; hypothetical protein 4099102 7114910 Mchl_3901 Methylobacterium extorquens CM4 hypothetical protein YP_002422641.1 4098659 R 440085 CDS YP_002422642.1 218531826 7114911 4099540..4100304 1 NC_011757.1 PFAM: enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_3610 enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase 4100304 7114911 Mchl_3902 Methylobacterium extorquens CM4 enoyl-CoA hydratase/isomerase YP_002422642.1 4099540 D 440085 CDS YP_002422643.1 218531827 7114912 4100313..4101164 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3611 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4101164 7114912 Mchl_3903 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422643.1 4100313 D 440085 CDS YP_002422644.1 218531828 7114913 4101161..4102015 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3612 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4102015 7114913 Mchl_3904 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422644.1 4101161 D 440085 CDS YP_002422645.1 218531829 7114914 4102041..4103045 1 NC_011757.1 TIGRFAM: magnesium and cobalt transporter CorA; PFAM: Mg+2 transporter protein CorA; KEGG: mex:Mext_3613 magnesium and cobalt transporter CorA; magnesium and cobalt transporter CorA 4103045 7114914 Mchl_3905 Methylobacterium extorquens CM4 magnesium and cobalt transporter CorA YP_002422645.1 4102041 D 440085 CDS YP_002422646.1 218531830 7114915 4103256..4103798 1 NC_011757.1 PFAM: protein of unknown function DUF892; KEGG: mex:Mext_3614 hypothetical protein; hypothetical protein 4103798 7114915 Mchl_3906 Methylobacterium extorquens CM4 hypothetical protein YP_002422646.1 4103256 D 440085 CDS YP_002422647.1 218531831 7114916 4104307..4106004 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0667 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4106004 7114916 Mchl_3907 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002422647.1 4104307 D 440085 CDS YP_002422648.1 218531832 7114917 complement(4106106..4106387) 1 NC_011757.1 KEGG: mex:Mext_3617 hypothetical protein; hypothetical protein 4106387 7114917 Mchl_3908 Methylobacterium extorquens CM4 hypothetical protein YP_002422648.1 4106106 R 440085 CDS YP_002422649.1 218531833 7114918 4107071..4107322 1 NC_011757.1 KEGG: mex:Mext_3618 hypothetical protein; hypothetical protein 4107322 7114918 Mchl_3909 Methylobacterium extorquens CM4 hypothetical protein YP_002422649.1 4107071 D 440085 CDS YP_002422650.1 218531834 7114919 complement(4107513..4107764) 1 NC_011757.1 KEGG: mex:Mext_3619 hypothetical protein; hypothetical protein 4107764 7114919 Mchl_3910 Methylobacterium extorquens CM4 hypothetical protein YP_002422650.1 4107513 R 440085 CDS YP_002422651.1 218531835 7114920 complement(4108069..4108473) 1 NC_011757.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: mex:Mext_3620 4-oxalocrotonate tautomerase; 4-oxalocrotonate tautomerase 4108473 7114920 Mchl_3911 Methylobacterium extorquens CM4 4-oxalocrotonate tautomerase YP_002422651.1 4108069 R 440085 CDS YP_002422652.1 218531836 7114921 4108572..4109420 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3621 regulatory protein LysR; LysR family transcriptional regulator 4109420 7114921 Mchl_3912 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422652.1 4108572 D 440085 CDS YP_002422653.1 218531837 7114922 4109720..4109914 1 NC_011757.1 KEGG: sus:acid_3821 CopG/Arc/MetJ family transcriptional regulator; CopG/Arc/MetJ family transcriptional regulator 4109914 7114922 Mchl_3913 Methylobacterium extorquens CM4 CopG/Arc/MetJ family transcriptional regulator YP_002422653.1 4109720 D 440085 CDS YP_002422654.1 218531838 7114923 4109920..4111974 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; KEGG: mex:Mext_3622 PAS sensor protein; multi-sensor hybrid histidine kinase 4111974 7114923 Mchl_3914 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002422654.1 4109920 D 440085 CDS YP_002422655.1 218531839 7114924 4112062..4112709 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_3623 regulatory protein TetR; TetR family transcriptional regulator 4112709 7114924 Mchl_3915 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002422655.1 4112062 D 440085 CDS YP_002422656.1 218531840 7114925 4112734..4113327 1 NC_011757.1 KEGG: mex:Mext_3624 hypothetical protein; hypothetical protein 4113327 7114925 Mchl_3916 Methylobacterium extorquens CM4 hypothetical protein YP_002422656.1 4112734 D 440085 CDS YP_002422657.1 218531841 7114926 4113393..4114109 1 NC_011757.1 KEGG: mex:Mext_3625 DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop; DNA-(apurinic or apyrimidinic site) lyase 4114109 7114926 Mchl_3917 Methylobacterium extorquens CM4 DNA-(apurinic or apyrimidinic site) lyase YP_002422657.1 4113393 D 440085 CDS YP_002422658.1 218531842 7114927 complement(4114218..4115138) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3626 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4115138 7114927 Mchl_3918 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422658.1 4114218 R 440085 CDS YP_002422659.1 218531843 7114928 4115262..4115834 1 NC_011757.1 PFAM: beta-Ig-H3/fasciclin; KEGG: mex:Mext_3627 beta-Ig-H3/fasciclin; beta-Ig-H3/fasciclin 4115834 7114928 Mchl_3919 Methylobacterium extorquens CM4 beta-Ig-H3/fasciclin YP_002422659.1 4115262 D 440085 CDS YP_002422660.1 218531844 7114929 4116080..4116916 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3628 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4116916 7114929 Mchl_3920 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422660.1 4116080 D 440085 CDS YP_002422661.1 218531845 7114930 complement(4116937..4117464) 1 NC_011757.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: mpo:Mpop_3911 glutathione-dependent formaldehyde-activating GFA; glutathione-dependent formaldehyde-activating protein 4117464 7114930 Mchl_3921 Methylobacterium extorquens CM4 glutathione-dependent formaldehyde-activating protein YP_002422661.1 4116937 R 440085 CDS YP_002422662.1 218531846 7114931 4117831..4118349 1 NC_011757.1 PFAM: GAF domain protein; KEGG: mex:Mext_3629 GAF domain-containing protein; GAF sensor protein 4118349 7114931 Mchl_3922 Methylobacterium extorquens CM4 GAF sensor protein YP_002422662.1 4117831 D 440085 CDS YP_002422663.1 218531847 7114932 4118410..4118628 1 NC_011757.1 KEGG: mex:Mext_3630 hypothetical protein; hypothetical protein 4118628 7114932 Mchl_3923 Methylobacterium extorquens CM4 hypothetical protein YP_002422663.1 4118410 D 440085 CDS YP_002422664.1 218531848 7114933 4118870..4119103 1 NC_011757.1 KEGG: mpo:Mpop_3914 hypothetical protein; hypothetical protein 4119103 7114933 Mchl_3924 Methylobacterium extorquens CM4 hypothetical protein YP_002422664.1 4118870 D 440085 CDS YP_002422665.1 218531849 7114934 4119108..4119356 1 NC_011757.1 KEGG: mex:Mext_3632 hypothetical protein; hypothetical protein 4119356 7114934 Mchl_3925 Methylobacterium extorquens CM4 hypothetical protein YP_002422665.1 4119108 D 440085 CDS YP_002422666.1 218531850 7114935 4119433..4120167 1 NC_011757.1 TIGRFAM: molybdate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3633 molybdate ABC transporter inner membrane subunit; molybdate ABC transporter inner membrane subunit 4120167 7114935 Mchl_3926 Methylobacterium extorquens CM4 molybdate ABC transporter inner membrane subunit YP_002422666.1 4119433 D 440085 CDS YP_002422667.1 218531851 7114936 complement(4120937..4121593) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_3634 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 4121593 7114936 Mchl_3927 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002422667.1 4120937 R 440085 CDS YP_002422668.1 218531852 7114937 4121779..4122873 1 NC_011757.1 KEGG: mex:Mext_3635 molybdate ABC transporter ATPase subunit; TIGRFAM: molybdate ABC transporter ATPase; PFAM: ABC transporter related; TOBE domain protein; SMART: ATPase AAA; molybdate ABC transporter ATPase 4122873 7114937 Mchl_3928 Methylobacterium extorquens CM4 molybdate ABC transporter ATPase YP_002422668.1 4121779 D 440085 CDS YP_002422669.1 218531853 7117127 4123437..4124141 1 NC_011757.1 KEGG: mex:Mext_3637 hypothetical protein; hypothetical protein 4124141 7117127 Mchl_3929 Methylobacterium extorquens CM4 hypothetical protein YP_002422669.1 4123437 D 440085 CDS YP_002422670.1 218531854 7117128 4124165..4125214 1 NC_011757.1 KEGG: mex:Mext_3638 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: pyridoxal phosphate biosynthetic protein PdxA; 4-hydroxythreonine-4-phosphate dehydrogenase 4125214 7117128 Mchl_3930 Methylobacterium extorquens CM4 4-hydroxythreonine-4-phosphate dehydrogenase YP_002422670.1 4124165 D 440085 CDS YP_002422671.1 218531855 7117129 4125223..4126113 1 NC_011757.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 4126113 ksgA 7117129 ksgA Methylobacterium extorquens CM4 dimethyladenosine transferase YP_002422671.1 4125223 D 440085 CDS YP_002422672.1 218531856 7117130 complement(4126771..4127817) 1 NC_011757.1 KEGG: mex:Mext_3640 hypothetical protein; hypothetical protein 4127817 7117130 Mchl_3932 Methylobacterium extorquens CM4 hypothetical protein YP_002422672.1 4126771 R 440085 CDS YP_002422673.1 218531857 7117131 complement(4127814..4129085) 1 NC_011757.1 PFAM: glycosyl transferase family 2; chitin synthase; KEGG: mex:Mext_3641 glycosyl transferase; family 2 glycosyl transferase 4129085 7117131 Mchl_3933 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002422673.1 4127814 R 440085 CDS YP_002422674.1 218531858 7117133 complement(4129602..4130717) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3642 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4130717 7117133 Mchl_3935 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422674.1 4129602 R 440085 CDS YP_002422675.1 218531859 7117134 complement(4130883..4132388) 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: mex:Mext_3643 sulfate transporter; sulfate transporter 4132388 7117134 Mchl_3936 Methylobacterium extorquens CM4 sulfate transporter YP_002422675.1 4130883 R 440085 CDS YP_002422676.1 218531860 7117135 complement(4132567..4133283) 1 NC_011757.1 PFAM: LrgB family protein; KEGG: mex:Mext_3644 LrgB family protein; LrgB family protein 4133283 7117135 Mchl_3937 Methylobacterium extorquens CM4 LrgB family protein YP_002422676.1 4132567 R 440085 CDS YP_002422677.1 218531861 7117136 complement(4133280..4133666) 1 NC_011757.1 PFAM: LrgA family protein; KEGG: mex:Mext_3645 LrgA family protein; LrgA family protein 4133666 7117136 Mchl_3938 Methylobacterium extorquens CM4 LrgA family protein YP_002422677.1 4133280 R 440085 CDS YP_002422678.1 218531862 7117137 complement(4133804..4134280) 1 NC_011757.1 PFAM: protein of unknown function DUF1332; KEGG: mex:Mext_3646 hypothetical protein; hypothetical protein 4134280 7117137 Mchl_3939 Methylobacterium extorquens CM4 hypothetical protein YP_002422678.1 4133804 R 440085 CDS YP_002422679.1 218531863 7117138 complement(4134541..4135269) 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_3647 methyltransferase type 11; type 11 methyltransferase 4135269 7117138 Mchl_3940 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002422679.1 4134541 R 440085 CDS YP_002422680.1 218531864 7117139 complement(4135297..4137927) 1 NC_011757.1 PFAM: OstA family protein; organic solvent tolerance protein; KEGG: mex:Mext_3648 organic solvent tolerance protein; organic solvent tolerance protein 4137927 7117139 Mchl_3941 Methylobacterium extorquens CM4 organic solvent tolerance protein YP_002422680.1 4135297 R 440085 CDS YP_002422681.1 218531865 7117140 complement(4137976..4139064) 1 NC_011757.1 PFAM: permease YjgP/YjgQ family protein; KEGG: mex:Mext_3649 permease YjgP/YjgQ family protein; permease YjgP/YjgQ family protein 4139064 7117140 Mchl_3942 Methylobacterium extorquens CM4 permease YjgP/YjgQ family protein YP_002422681.1 4137976 R 440085 CDS YP_002422682.1 218531866 7117141 complement(4139075..4140244) 1 NC_011757.1 PFAM: permease YjgP/YjgQ family protein; KEGG: mex:Mext_3650 permease YjgP/YjgQ family protein; permease YjgP/YjgQ family protein 4140244 7117141 Mchl_3943 Methylobacterium extorquens CM4 permease YjgP/YjgQ family protein YP_002422682.1 4139075 R 440085 CDS YP_002422683.1 218531867 7117142 4140536..4142029 1 NC_011757.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: mex:Mext_3651 leucyl aminopeptidase; leucyl aminopeptidase 4142029 7117142 Mchl_3944 Methylobacterium extorquens CM4 leucyl aminopeptidase YP_002422683.1 4140536 D 440085 CDS YP_002422684.1 218531868 7117143 4142026..4142826 1 NC_011757.1 KEGG: mex:Mext_3652 hypothetical protein; hypothetical protein 4142826 7117143 Mchl_3945 Methylobacterium extorquens CM4 hypothetical protein YP_002422684.1 4142026 D 440085 CDS YP_002422685.1 218531869 7117144 4142926..4144662 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_3653 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 4144662 7117144 Mchl_3946 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002422685.1 4142926 D 440085 CDS YP_002422686.1 218531870 7117145 4145126..4146307 1 NC_011757.1 PFAM: MscS Mechanosensitive ion channel; KEGG: mex:Mext_3654 MscS mechanosensitive ion channel; mechanosensitive ion channel MscS 4146307 7117145 Mchl_3947 Methylobacterium extorquens CM4 mechanosensitive ion channel MscS YP_002422686.1 4145126 D 440085 CDS YP_002422687.1 218531871 7117146 complement(4146373..4147152) 1 NC_011757.1 PFAM: DSBA oxidoreductase; KEGG: mex:Mext_3655 DsbA oxidoreductase; DSBA oxidoreductase 4147152 7117146 Mchl_3948 Methylobacterium extorquens CM4 DSBA oxidoreductase YP_002422687.1 4146373 R 440085 CDS YP_002422688.1 218531872 7117147 4147450..4148493 1 NC_011757.1 KEGG: mex:Mext_3656 metal dependent phophohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 4148493 7117147 Mchl_3949 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002422688.1 4147450 D 440085 CDS YP_002422689.1 218531873 7117148 4148592..4149932 1 NC_011757.1 PFAM: phosphate-selective porin O and P; KEGG: mex:Mext_3657 phosphate-selective porin O and P; phosphate-selective porin O and P 4149932 7117148 Mchl_3950 Methylobacterium extorquens CM4 phosphate-selective porin O and P YP_002422689.1 4148592 D 440085 CDS YP_002422690.1 218531874 7117149 4150011..4151174 1 NC_011757.1 PFAM: aminotransferase class I and II; KEGG: mex:Mext_3658 aminotransferase class I and II; class I and II aminotransferase 4151174 7117149 Mchl_3951 Methylobacterium extorquens CM4 class I and II aminotransferase YP_002422690.1 4150011 D 440085 CDS YP_002422691.1 218531875 7117150 complement(4151377..4154517) 1 NC_011757.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: ribonuclease E and G; KEGG: mex:Mext_3659 ribonuclease; Rne/Rng family ribonuclease 4154517 7117150 Mchl_3952 Methylobacterium extorquens CM4 Rne/Rng family ribonuclease YP_002422691.1 4151377 R 440085 CDS YP_002422692.1 218531876 7117151 4155204..4155389 1 NC_011757.1 KEGG: mex:Mext_3660 hypothetical protein; hypothetical protein 4155389 7117151 Mchl_3953 Methylobacterium extorquens CM4 hypothetical protein YP_002422692.1 4155204 D 440085 CDS YP_002422693.1 218531877 7117152 4155582..4156913 1 NC_011757.1 PFAM: cell wall hydrolase/autolysin; KEGG: mex:Mext_3661 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 4156913 7117152 Mchl_3954 Methylobacterium extorquens CM4 N-acetylmuramoyl-L-alanine amidase YP_002422693.1 4155582 D 440085 CDS YP_002422694.1 218531878 7117153 4157240..4159657 1 NC_011757.1 KEGG: mex:Mext_3662 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; penicillin-binding protein, 1A family 4159657 7117153 Mchl_3955 Methylobacterium extorquens CM4 penicillin-binding protein, 1A family YP_002422694.1 4157240 D 440085 CDS YP_002422695.1 218531879 7117154 4159950..4161062 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_3663 alkanesulfonate monooxygenase; alkanesulfonate monooxygenase 4161062 7117154 Mchl_3956 Methylobacterium extorquens CM4 alkanesulfonate monooxygenase YP_002422695.1 4159950 D 440085 CDS YP_002422696.1 218531880 7117155 4161248..4162507 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_3664 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 4162507 7117155 Mchl_3957 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase type 2 domain-containing protein YP_002422696.1 4161248 D 440085 CDS YP_002422697.1 218531881 7117156 4162666..4163316 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_3665 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 4163316 7117156 Mchl_3958 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002422697.1 4162666 D 440085 CDS YP_002422698.1 218531882 7117157 4163330..4164304 1 NC_011757.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mex:Mext_3666 molybdopterin dehydrogenase FAD-binding; FAD-binding molybdopterin dehydrogenase 4164304 7117157 Mchl_3959 Methylobacterium extorquens CM4 FAD-binding molybdopterin dehydrogenase YP_002422698.1 4163330 D 440085 CDS YP_002422699.1 218531883 7117158 4164316..4166553 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_3667 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 4166553 7117158 Mchl_3960 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002422699.1 4164316 D 440085 CDS YP_002422700.1 218531884 7117159 4166679..4166933 1 NC_011757.1 KEGG: mex:Mext_3668 hypothetical protein; hypothetical protein 4166933 7117159 Mchl_3961 Methylobacterium extorquens CM4 hypothetical protein YP_002422700.1 4166679 D 440085 CDS YP_002422701.1 218531885 7117160 4167043..4168383 1 NC_011757.1 PFAM: xanthine/uracil/vitamin C permease; KEGG: mex:Mext_3669 xanthine/uracil/vitamin C permease; xanthine/uracil/vitamin C permease 4168383 7117160 Mchl_3962 Methylobacterium extorquens CM4 xanthine/uracil/vitamin C permease YP_002422701.1 4167043 D 440085 CDS YP_002422702.1 218531886 7117161 4168527..4168718 1 NC_011757.1 KEGG: mpo:Mpop_3957 hypothetical protein; hypothetical protein 4168718 7117161 Mchl_3963 Methylobacterium extorquens CM4 hypothetical protein YP_002422702.1 4168527 D 440085 CDS YP_002422703.1 218531887 7117162 complement(4168707..4169738) 1 NC_011757.1 PFAM: monooxygenase; KEGG: mex:Mext_3670 luciferase family protein; monooxygenase 4169738 7117162 Mchl_3964 Methylobacterium extorquens CM4 monooxygenase YP_002422703.1 4168707 R 440085 CDS YP_002422704.1 218531888 7117163 4170331..4170555 1 NC_011757.1 KEGG: mex:Mext_3671 hypothetical protein; hypothetical protein 4170555 7117163 Mchl_3965 Methylobacterium extorquens CM4 hypothetical protein YP_002422704.1 4170331 D 440085 CDS YP_002422705.1 218531889 7117164 complement(4171023..4171229) 1 NC_011757.1 KEGG: mpo:Mpop_0104 hypothetical protein; hypothetical protein 4171229 7117164 Mchl_3966 Methylobacterium extorquens CM4 hypothetical protein YP_002422705.1 4171023 R 440085 CDS YP_002422706.1 218531890 7117166 complement(4172136..4173305) 1 NC_011757.1 KEGG: mex:Mext_3673 DHH superfamily phosphohydrolase; DHH superfamily phosphohydrolase 4173305 7117166 Mchl_3968 Methylobacterium extorquens CM4 DHH superfamily phosphohydrolase YP_002422706.1 4172136 R 440085 CDS YP_002422707.1 218531891 7117167 4173719..4175365 1 NC_011757.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 4175365 mdoG 7117167 mdoG Methylobacterium extorquens CM4 glucan biosynthesis protein G YP_002422707.1 4173719 D 440085 CDS YP_002422708.1 218531892 7117168 4175417..4177591 1 NC_011757.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 4177591 7117168 Mchl_3970 Methylobacterium extorquens CM4 glucosyltransferase MdoH YP_002422708.1 4175417 D 440085 CDS YP_002422709.1 218531893 7117173 4179371..4180933 1 NC_011757.1 PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: atu:Atu5094 ISL3 family transposase; transposase IS204/IS1001/IS1096/IS1165 family protein 4180933 7117173 Mchl_3974 Methylobacterium extorquens CM4 transposase IS204/IS1001/IS1096/IS1165 family protein YP_002422709.1 4179371 D 440085 CDS YP_002422710.1 218531894 7117176 complement(4182435..4183490) 1 NC_011757.1 KEGG: csc:Csac_0779 GDSL family lipase; hypothetical protein 4183490 7117176 Mchl_3977 Methylobacterium extorquens CM4 hypothetical protein YP_002422710.1 4182435 R 440085 CDS YP_002422711.1 218531895 7117177 complement(4183594..4184628) 1 NC_011757.1 PFAM: oxidoreductase domain protein; KEGG: scl:sce7613 oxidoreductase; oxidoreductase domain-containing protein 4184628 7117177 Mchl_3978 Methylobacterium extorquens CM4 oxidoreductase domain-containing protein YP_002422711.1 4183594 R 440085 CDS YP_002422712.1 218531896 7117178 4184792..4185874 1 NC_011757.1 PFAM: CBS domain containing protein; nucleotidyl transferase; KEGG: sru:SRU_0607 mannose-1-phosphate guanyltransferase; nucleotidyl transferase 4185874 7117178 Mchl_3979 Methylobacterium extorquens CM4 nucleotidyl transferase YP_002422712.1 4184792 D 440085 CDS YP_002422713.1 218531897 7117179 4185921..4186973 1 NC_011757.1 PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; KEGG: mag:amb0080 sialic acid synthase; N-acylneuraminate-9-phosphate synthase 4186973 7117179 Mchl_3980 Methylobacterium extorquens CM4 N-acylneuraminate-9-phosphate synthase YP_002422713.1 4185921 D 440085 CDS YP_002422714.1 218531898 7117180 4186973..4187650 1 NC_011757.1 KEGG: ajs:Ajs_0546 hypothetical protein; hypothetical protein 4187650 7117180 Mchl_3981 Methylobacterium extorquens CM4 hypothetical protein YP_002422714.1 4186973 D 440085 CDS YP_002422715.1 218531899 7117181 4187656..4188840 1 NC_011757.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: cvi:CV_4033 N-acetylglucosamine-6-phosphate 2-epimerase/N-acetylglucosamine-6-phosphatase; UDP-N-acetylglucosamine 2-epimerase 4188840 7117181 Mchl_3982 Methylobacterium extorquens CM4 UDP-N-acetylglucosamine 2-epimerase YP_002422715.1 4187656 D 440085 CDS YP_002422716.1 218531900 7117182 4188837..4189958 1 NC_011757.1 KEGG: mca:MCA2548 hypothetical protein; hypothetical protein 4189958 7117182 Mchl_3983 Methylobacterium extorquens CM4 hypothetical protein YP_002422716.1 4188837 D 440085 CDS YP_002422717.1 218531901 7117183 4189972..4190940 1 NC_011757.1 PFAM: polysaccharide deacetylase; KEGG: mgm:Mmc1_0148 polysaccharide deacetylase; polysaccharide deacetylase 4190940 7117183 Mchl_3984 Methylobacterium extorquens CM4 polysaccharide deacetylase YP_002422717.1 4189972 D 440085 CDS YP_002422718.1 218531902 7117184 4190930..4192168 1 NC_011757.1 PFAM: polysaccharide biosynthesis protein CapD; KEGG: bfr:BF1430 nucleoside-diphosphate sugar epimerase; polysaccharide biosynthesis protein CapD 4192168 7117184 Mchl_3985 Methylobacterium extorquens CM4 polysaccharide biosynthesis protein CapD YP_002422718.1 4190930 D 440085 CDS YP_002422719.1 218531903 7117185 4192204..4193355 1 NC_011757.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mag:amb0078 pyridoxal phosphate-dependent enzyme; DegT/DnrJ/EryC1/StrS aminotransferase 4193355 7117185 Mchl_3986 Methylobacterium extorquens CM4 DegT/DnrJ/EryC1/StrS aminotransferase YP_002422719.1 4192204 D 440085 CDS YP_002422720.1 218531904 7117186 4193481..4195124 1 NC_011757.1 hypothetical protein 4195124 7117186 Mchl_3987 Methylobacterium extorquens CM4 hypothetical protein YP_002422720.1 4193481 D 440085 CDS YP_002422721.1 218531905 7117187 4195163..4196086 1 NC_011757.1 PFAM: oxidoreductase domain protein; KEGG: dau:Daud_0025 oxidoreductase domain protein; oxidoreductase domain-containing protein 4196086 7117187 Mchl_3988 Methylobacterium extorquens CM4 oxidoreductase domain-containing protein YP_002422721.1 4195163 D 440085 CDS YP_002422722.1 218531906 7117188 4196062..4197534 1 NC_011757.1 KEGG: gbe:GbCGDNIH1_2152 glycosyltransferase; hypothetical protein 4197534 7117188 Mchl_3989 Methylobacterium extorquens CM4 hypothetical protein YP_002422722.1 4196062 D 440085 CDS YP_002422723.1 218531907 7117189 4197589..4198320 1 NC_011757.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: bja:blr5996 posttranslational modification protein; N-acylneuraminate cytidylyltransferase 4198320 7117189 Mchl_3990 Methylobacterium extorquens CM4 N-acylneuraminate cytidylyltransferase YP_002422723.1 4197589 D 440085 CDS YP_002422724.1 218531908 7117190 4198674..4200269 1 NC_011757.1 hypothetical protein 4200269 7117190 Mchl_3991 Methylobacterium extorquens CM4 hypothetical protein YP_002422724.1 4198674 D 440085 CDS YP_002422725.1 218531909 7117191 4200604..4204557 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: bxe:Bxe_A3797 hypothetical protein; family 2 glycosyl transferase 4204557 7117191 Mchl_3992 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002422725.1 4200604 D 440085 CDS YP_002422726.1 218531910 7117192 4204571..4205491 1 NC_011757.1 KEGG: mlo:mll8033 hypothetical protein; hypothetical protein 4205491 7117192 Mchl_3993 Methylobacterium extorquens CM4 hypothetical protein YP_002422726.1 4204571 D 440085 CDS YP_002422727.1 218531911 7117193 complement(4205794..4206837) 1 NC_011757.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: oan:Oant_4496 transposase IS116/IS110/IS902 family protein; transposase IS116/IS110/IS902 family protein 4206837 7117193 Mchl_3994 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002422727.1 4205794 R 440085 CDS YP_002422728.1 218531912 7117194 4207024..4207779 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mex:Mext_3531 integrase catalytic region; integrase catalytic subunit 4207779 7117194 Mchl_3995 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002422728.1 4207024 D 440085 CDS YP_002422729.1 218531913 7117195 complement(4207815..4208438) 1 NC_011757.1 KEGG: mex:Mext_2439 hypothetical protein; hypothetical protein 4208438 7117195 Mchl_3996 Methylobacterium extorquens CM4 hypothetical protein YP_002422729.1 4207815 R 440085 CDS YP_002422730.1 218531914 7117196 complement(4208435..4208995) 1 NC_011757.1 KEGG: mex:Mext_2440 hypothetical protein; hypothetical protein 4208995 7117196 Mchl_3997 Methylobacterium extorquens CM4 hypothetical protein YP_002422730.1 4208435 R 440085 CDS YP_002422731.1 218531915 7117197 4209182..4209937 1 NC_011757.1 KEGG: mem:Memar_0194 hypothetical protein; hypothetical protein 4209937 7117197 Mchl_3998 Methylobacterium extorquens CM4 hypothetical protein YP_002422731.1 4209182 D 440085 CDS YP_002422732.1 218531916 7117199 complement(4211006..4211671) 1 NC_011757.1 KEGG: fal:FRAAL1676 modular polyketide synthase; hypothetical protein 4211671 7117199 Mchl_4000 Methylobacterium extorquens CM4 hypothetical protein YP_002422732.1 4211006 R 440085 CDS YP_002422733.1 218531917 7117200 complement(4211749..4212633) 1 NC_011757.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; KEGG: mex:Mext_2395 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 4212633 7117200 Mchl_4001 Methylobacterium extorquens CM4 glucose-1-phosphate thymidylyltransferase YP_002422733.1 4211749 R 440085 CDS YP_002422734.1 218531918 7117201 complement(4212650..4213540) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3692 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 4213540 7117201 Mchl_4002 Methylobacterium extorquens CM4 dTDP-4-dehydrorhamnose reductase YP_002422734.1 4212650 R 440085 CDS YP_002422735.1 218531919 7117202 complement(4213543..4214601) 1 NC_011757.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_3691 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 4214601 7117202 Mchl_4003 Methylobacterium extorquens CM4 dTDP-glucose 4,6-dehydratase YP_002422735.1 4213543 R 440085 CDS YP_002422736.1 218531920 7117203 complement(4214735..4215289) 1 NC_011757.1 KEGG: mex:Mext_3690 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 4215289 7117203 Mchl_4004 Methylobacterium extorquens CM4 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002422736.1 4214735 R 440085 CDS YP_002422737.1 218531921 7117204 4215645..4218017 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: bpy:Bphyt_0883 glycosyl transferase family 2; family 2 glycosyl transferase 4218017 7117204 Mchl_4005 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002422737.1 4215645 D 440085 CDS YP_002422738.1 218531922 7114361 4220468..4220650 1 NC_011757.1 KEGG: mex:Mext_3718 hypothetical protein; hypothetical protein 4220650 7114361 Mchl_4010 Methylobacterium extorquens CM4 hypothetical protein YP_002422738.1 4220468 D 440085 CDS YP_002422739.1 218531923 7118016 4220894..4221109 1 NC_011757.1 KEGG: mrd:Mrad2831_4949 hypothetical protein; hypothetical protein 4221109 7118016 Mchl_4011 Methylobacterium extorquens CM4 hypothetical protein YP_002422739.1 4220894 D 440085 CDS YP_002422740.1 218531924 7118017 4221433..4221960 1 NC_011757.1 KEGG: mex:Mext_3719 hypothetical protein; hypothetical protein 4221960 7118017 Mchl_4012 Methylobacterium extorquens CM4 hypothetical protein YP_002422740.1 4221433 D 440085 CDS YP_002422741.1 218531925 7118018 complement(4222006..4222227) 1 NC_011757.1 KEGG: mex:Mext_3720 hypothetical protein; hypothetical protein 4222227 7118018 Mchl_4013 Methylobacterium extorquens CM4 hypothetical protein YP_002422741.1 4222006 R 440085 CDS YP_002422742.1 218531926 7118019 complement(4222450..4222665) 1 NC_011757.1 KEGG: mrd:Mrad2831_4166 hypothetical protein; hypothetical protein 4222665 7118019 Mchl_4014 Methylobacterium extorquens CM4 hypothetical protein YP_002422742.1 4222450 R 440085 CDS YP_002422743.1 218531927 7118020 complement(4222789..4224624) 1 NC_011757.1 catalyzes the hydrolysis of allophanate; allophanate hydrolase 4224624 7118020 Mchl_4015 Methylobacterium extorquens CM4 allophanate hydrolase YP_002422743.1 4222789 R 440085 CDS YP_002422744.1 218531928 7118021 complement(4224732..4224851) 1 NC_011757.1 hypothetical protein 4224851 7118021 Mchl_4016 Methylobacterium extorquens CM4 hypothetical protein YP_002422744.1 4224732 R 440085 CDS YP_002422745.1 218531929 7118022 complement(4224935..4228465) 1 NC_011757.1 KEGG: mex:Mext_3722 UreA carboxylase; TIGRFAM: urea amidolyase related protein; urea carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; allophanate hydrolase subunit 2; carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SMART: allophanate hydrolase subunit 1; urea carboxylase 4228465 7118022 Mchl_4017 Methylobacterium extorquens CM4 urea carboxylase YP_002422745.1 4224935 R 440085 CDS YP_002422746.1 218531930 7118023 complement(4228470..4229090) 1 NC_011757.1 TIGRFAM: urea carboxylase-associated protein 1; KEGG: mex:Mext_3723 hypothetical protein; urea carboxylase-associated protein 1 4229090 7118023 Mchl_4018 Methylobacterium extorquens CM4 urea carboxylase-associated protein 1 YP_002422746.1 4228470 R 440085 CDS YP_002422747.1 218531931 7118024 complement(4229105..4229914) 1 NC_011757.1 TIGRFAM: urea carboxylase-associated protein 2; KEGG: mex:Mext_3724 hypothetical protein; urea carboxylase-associated protein 2 4229914 7118024 Mchl_4019 Methylobacterium extorquens CM4 urea carboxylase-associated protein 2 YP_002422747.1 4229105 R 440085 CDS YP_002422748.1 218531932 7118025 complement(4230140..4230511) 1 NC_011757.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: mex:Mext_3725 protein of unknown function DUF861 cupin_3; hypothetical protein 4230511 7118025 Mchl_4020 Methylobacterium extorquens CM4 hypothetical protein YP_002422748.1 4230140 R 440085 CDS YP_002422749.1 218531933 7118026 complement(4230524..4231897) 1 NC_011757.1 TIGRFAM: glutamine synthetaseII; PFAM: glutamine synthetase catalytic region; KEGG: mex:Mext_3726 glutamine synthetase, type III; glutamine synthetaseII 4231897 7118026 Mchl_4021 Methylobacterium extorquens CM4 glutamine synthetaseII YP_002422749.1 4230524 R 440085 CDS YP_002422750.1 218531934 7118027 complement(4231899..4232699) 1 NC_011757.1 PFAM: creatininase; KEGG: mex:Mext_3727 creatininase; creatininase 4232699 7118027 Mchl_4022 Methylobacterium extorquens CM4 creatininase YP_002422750.1 4231899 R 440085 CDS YP_002422751.1 218531935 7118028 complement(4232696..4233646) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3728 ABC transporter; ABC transporter 4233646 7118028 Mchl_4023 Methylobacterium extorquens CM4 ABC transporter YP_002422751.1 4232696 R 440085 CDS YP_002422752.1 218531936 7118029 complement(4233643..4234704) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3729 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4234704 7118029 Mchl_4024 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422752.1 4233643 R 440085 CDS YP_002422753.1 218531937 7118030 complement(4234715..4235725) 1 NC_011757.1 KEGG: mex:Mext_3730 ABC transporter substrate-binding protein; ABC transporter substrate-binding protein 4235725 7118030 Mchl_4025 Methylobacterium extorquens CM4 ABC transporter substrate-binding protein YP_002422753.1 4234715 R 440085 CDS YP_002422754.1 218531938 7118031 4236727..4238055 1 NC_011757.1 KEGG: mex:Mext_3731 glycine betaine/L-proline ABC transporter ATPase; TIGRFAM: glycine betaine/L-proline ABC transporter ATPase; PFAM: CBS domain containing protein; ABC transporter related; SMART: ATPase AAA; glycine betaine/L-proline ABC transporter ATPase subunit 4238055 7118031 Mchl_4026 Methylobacterium extorquens CM4 glycine betaine/L-proline ABC transporter ATPase subunit YP_002422754.1 4236727 D 440085 CDS YP_002422755.1 218531939 7118032 4237971..4238822 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3732 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4238822 7118032 Mchl_4027 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422755.1 4237971 D 440085 CDS YP_002422756.1 218531940 7118033 4239008..4239844 1 NC_011757.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; KEGG: mex:Mext_3733 substrate-binding region of ABC-type glycine betaine transporter; glycine betaine ABC transporter substrate-binding protein 4239844 7118033 Mchl_4028 Methylobacterium extorquens CM4 glycine betaine ABC transporter substrate-binding protein YP_002422756.1 4239008 D 440085 CDS YP_002422757.1 218531941 7118034 4239925..4241274 1 NC_011757.1 KEGG: mex:Mext_3734 signal peptide; signal peptide 4241274 7118034 Mchl_4029 Methylobacterium extorquens CM4 signal peptide YP_002422757.1 4239925 D 440085 CDS YP_002422758.1 218531942 7118035 complement(4241468..4242499) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: mex:Mext_3735 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 4242499 7118035 Mchl_4030 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002422758.1 4241468 R 440085 CDS YP_002422759.1 218531943 7118036 4242936..4244189 1 NC_011757.1 TIGRFAM: sarcosine oxidase subunit beta family; PFAM: FAD dependent oxidoreductase; KEGG: mex:Mext_3736 sarcosine oxidase subunit beta family protein; sarcosine oxidase subunit beta family 4244189 7118036 Mchl_4031 Methylobacterium extorquens CM4 sarcosine oxidase subunit beta family YP_002422759.1 4242936 D 440085 CDS YP_002422760.1 218531944 7118037 4244209..4244505 1 NC_011757.1 TIGRFAM: sarcosine oxidase subunit delta family; PFAM: sarcosine oxidase subunit delta heterotetrameric; KEGG: mex:Mext_3737 sarcosine oxidase subunit delta family protein; sarcosine oxidase subunit delta family 4244505 7118037 Mchl_4032 Methylobacterium extorquens CM4 sarcosine oxidase subunit delta family YP_002422760.1 4244209 D 440085 CDS YP_002422761.1 218531945 7118038 4244507..4247494 1 NC_011757.1 TIGRFAM: sarcosine oxidase subunit alpha family; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; KEGG: mex:Mext_3738 sarcosine oxidase subunit alpha family protein; sarcosine oxidase subunit alpha family 4247494 7118038 Mchl_4033 Methylobacterium extorquens CM4 sarcosine oxidase subunit alpha family YP_002422761.1 4244507 D 440085 CDS YP_002422762.1 218531946 7118039 4247487..4248077 1 NC_011757.1 PFAM: sarcosine oxidase subunit gamma; KEGG: mex:Mext_3739 sarcosine oxidase subunit gamma; sarcosine oxidase subunit gamma 4248077 7118039 Mchl_4034 Methylobacterium extorquens CM4 sarcosine oxidase subunit gamma YP_002422762.1 4247487 D 440085 CDS YP_002422763.1 218531947 7118040 4248220..4249581 1 NC_011757.1 KEGG: mex:Mext_3740 L-serine dehydratase; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 4249581 7118040 Mchl_4035 Methylobacterium extorquens CM4 L-serine dehydratase YP_002422763.1 4248220 D 440085 CDS YP_002422764.1 218531948 7118041 4250009..4250230 1 NC_011757.1 KEGG: mex:Mext_3741 hypothetical protein; hypothetical protein 4250230 7118041 Mchl_4036 Methylobacterium extorquens CM4 hypothetical protein YP_002422764.1 4250009 D 440085 CDS YP_002422765.1 218531949 7118042 complement(4250530..4251039) 1 NC_011757.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: mex:Mext_3742 YbaK/prolyl-tRNA synthetase associated region; YbaK/prolyl-tRNA synthetase associated protein 4251039 7118042 Mchl_4037 Methylobacterium extorquens CM4 YbaK/prolyl-tRNA synthetase associated protein YP_002422765.1 4250530 R 440085 CDS YP_002422766.1 218531950 7118043 complement(4251053..4251847) 1 NC_011757.1 PFAM: electron transfer flavoprotein alpha/beta-subunit; KEGG: mex:Mext_3743 electron transfer flavoprotein beta-subunit; electron transfer flavoprotein alpha/beta-subunit 4251847 7118043 Mchl_4038 Methylobacterium extorquens CM4 electron transfer flavoprotein alpha/beta-subunit YP_002422766.1 4251053 R 440085 CDS YP_002422767.1 218531951 7118044 complement(4251844..4253064) 1 NC_011757.1 PFAM: electron transfer flavoprotein alpha/beta-subunit ; electron transfer flavoprotein subunit alpha; KEGG: mex:Mext_3744 electron transfer flavoprotein subunit alpha; electron transfer flavoprotein subunit alpha 4253064 7118044 Mchl_4039 Methylobacterium extorquens CM4 electron transfer flavoprotein subunit alpha YP_002422767.1 4251844 R 440085 CDS YP_002422768.1 218531952 7118045 complement(4253061..4254962) 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: mex:Mext_3745 hypothetical protein; hypothetical protein 4254962 7118045 Mchl_4040 Methylobacterium extorquens CM4 hypothetical protein YP_002422768.1 4253061 R 440085 CDS YP_002422769.1 218531953 7118046 complement(4255225..4257267) 1 NC_011757.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_3746 NADH:flavin oxidoreductase/NADH oxidase; NADH:flavin oxidoreductase/NADH oxidase 4257267 7118046 Mchl_4041 Methylobacterium extorquens CM4 NADH:flavin oxidoreductase/NADH oxidase YP_002422769.1 4255225 R 440085 CDS YP_002422770.1 218531954 7118047 complement(4257330..4258457) 1 NC_011757.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: mex:Mext_3747 oxidoreductase FAD-binding subunit; oxidoreductase FAD-binding domain-containing protein 4258457 7118047 Mchl_4042 Methylobacterium extorquens CM4 oxidoreductase FAD-binding domain-containing protein YP_002422770.1 4257330 R 440085 CDS YP_002422771.1 218531955 7118048 complement(4258461..4259720) 1 NC_011757.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: mex:Mext_3748 Rieske (2Fe-2S) domain-containing protein; Rieske (2Fe-2S) domain-containing protein 4259720 7118048 Mchl_4043 Methylobacterium extorquens CM4 Rieske (2Fe-2S) domain-containing protein YP_002422771.1 4258461 R 440085 CDS YP_002422772.1 218531956 7118049 complement(4259845..4260651) 1 NC_011757.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: mex:Mext_3749 histidinol-phosphate phosphatase; histidinol-phosphate phosphatase 4260651 7118049 Mchl_4044 Methylobacterium extorquens CM4 histidinol-phosphate phosphatase YP_002422772.1 4259845 R 440085 CDS YP_002422773.1 218531957 7118050 complement(4260655..4261590) 1 NC_011757.1 PFAM: choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: mex:Mext_3750 choline/ethanolamine kinase; choline/ethanolamine kinase 4261590 7118050 Mchl_4045 Methylobacterium extorquens CM4 choline/ethanolamine kinase YP_002422773.1 4260655 R 440085 CDS YP_002422774.1 218531958 7118051 complement(4261811..4262791) 1 NC_011757.1 PFAM: aminoglycoside phosphotransferase; KEGG: mex:Mext_3751 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 4262791 7118051 Mchl_4046 Methylobacterium extorquens CM4 aminoglycoside phosphotransferase YP_002422774.1 4261811 R 440085 CDS YP_002422775.1 218531959 7118052 complement(4262788..4264089) 1 NC_011757.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 4264089 7118052 Mchl_4047 Methylobacterium extorquens CM4 allantoate amidohydrolase YP_002422775.1 4262788 R 440085 CDS YP_002422776.1 218531960 7118053 complement(4264113..4265951) 1 NC_011757.1 KEGG: mex:Mext_3753 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; oligopeptide/dipeptide ABC transporter ATPase 4265951 7118053 Mchl_4048 Methylobacterium extorquens CM4 oligopeptide/dipeptide ABC transporter ATPase YP_002422776.1 4264113 R 440085 CDS YP_002422777.1 218531961 7118054 complement(4265951..4266874) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3754 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4266874 7118054 Mchl_4049 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422777.1 4265951 R 440085 CDS YP_002422778.1 218531962 7118055 complement(4266874..4267854) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3755 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4267854 7118055 Mchl_4050 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422778.1 4266874 R 440085 CDS YP_002422779.1 218531963 7118056 complement(4267947..4269518) 1 NC_011757.1 PFAM: extracellular solute-binding protein family 5; KEGG: mex:Mext_3756 extracellular solute-binding protein; family 5 extracellular solute-binding protein 4269518 7118056 Mchl_4051 Methylobacterium extorquens CM4 family 5 extracellular solute-binding protein YP_002422779.1 4267947 R 440085 CDS YP_002422780.1 218531964 7118057 complement(4269852..4272371) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB short domain; TonB-dependent receptor plug; KEGG: mex:Mext_3757 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 4272371 7118057 Mchl_4052 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002422780.1 4269852 R 440085 CDS YP_002422781.1 218531965 7118058 complement(4272542..4273516) 1 NC_011757.1 PFAM: FecR protein; KEGG: mex:Mext_3758 FecR protein; anti-FecI sigma factor FecR 4273516 7118058 Mchl_4053 Methylobacterium extorquens CM4 anti-FecI sigma factor FecR YP_002422781.1 4272542 R 440085 CDS YP_002422782.1 218531966 7118059 complement(4273614..4274156) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_3759 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 4274156 7118059 Mchl_4054 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002422782.1 4273614 R 440085 CDS YP_002422783.1 218531967 7118060 4275014..4276798 1 NC_011757.1 PFAM: IucA/IucC family protein; KEGG: mex:Mext_3760 IucA/IucC family protein; IucA/IucC family protein 4276798 7118060 Mchl_4055 Methylobacterium extorquens CM4 IucA/IucC family protein YP_002422783.1 4275014 D 440085 CDS YP_002422784.1 218531968 7118061 4276782..4279778 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; IucA/IucC family protein; KEGG: mex:Mext_3761 IucA/IucC family protein; IucA/IucC family protein 4279778 7118061 Mchl_4056 Methylobacterium extorquens CM4 IucA/IucC family protein YP_002422784.1 4276782 D 440085 CDS YP_002422785.1 218531969 7118062 4279775..4281076 1 NC_011757.1 KEGG: mex:Mext_3762 hypothetical protein; hypothetical protein 4281076 7118062 Mchl_4057 Methylobacterium extorquens CM4 hypothetical protein YP_002422785.1 4279775 D 440085 CDS YP_002422786.1 218531970 7118063 4281073..4281909 1 NC_011757.1 PFAM: xylose isomerase; KEGG: mex:Mext_3763 xylose isomerase domain-containing protein; xylose isomerase 4281909 7118063 Mchl_4058 Methylobacterium extorquens CM4 xylose isomerase YP_002422786.1 4281073 D 440085 CDS YP_002422787.1 218531971 7114363 4281938..4282216 1 NC_011757.1 KEGG: mex:Mext_3764 hypothetical protein; hypothetical protein 4282216 7114363 Mchl_4059 Methylobacterium extorquens CM4 hypothetical protein YP_002422787.1 4281938 D 440085 CDS YP_002422788.1 218531972 7114366 4282520..4283020 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_3765 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4283020 7114366 Mchl_4060 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002422788.1 4282520 D 440085 CDS YP_002422789.1 218531973 7114367 4283188..4283865 1 NC_011757.1 KEGG: mex:Mext_3766 hypothetical protein; hypothetical protein 4283865 7114367 Mchl_4061 Methylobacterium extorquens CM4 hypothetical protein YP_002422789.1 4283188 D 440085 CDS YP_002422790.1 218531974 7114368 complement(4283965..4284738) 1 NC_011757.1 KEGG: mex:Mext_3768 TetR family transcriptional regulator; TetR family transcriptional regulator 4284738 7114368 Mchl_4062 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002422790.1 4283965 R 440085 CDS YP_002422791.1 218531975 7114369 complement(4284809..4285642) 1 NC_011757.1 KEGG: mex:Mext_3769 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; pyrroline-5-carboxylate reductase 4285642 7114369 Mchl_4063 Methylobacterium extorquens CM4 pyrroline-5-carboxylate reductase YP_002422791.1 4284809 R 440085 CDS YP_002422792.1 218531976 7114370 complement(4285724..4286230) 1 NC_011757.1 PFAM: protein of unknown function DUF1790; KEGG: mex:Mext_3770 hypothetical protein; hypothetical protein 4286230 7114370 Mchl_4064 Methylobacterium extorquens CM4 hypothetical protein YP_002422792.1 4285724 R 440085 CDS YP_002422793.1 218531977 7114371 complement(4286547..4286828) 1 NC_011757.1 PFAM: protein of unknown function DUF526; KEGG: mex:Mext_3771 hypothetical protein; hypothetical protein 4286828 7114371 Mchl_4065 Methylobacterium extorquens CM4 hypothetical protein YP_002422793.1 4286547 R 440085 CDS YP_002422794.1 218531978 7114372 4287071..4287796 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_3772 response regulator receiver; transcriptional regulator 4287796 7114372 Mchl_4066 Methylobacterium extorquens CM4 transcriptional regulator YP_002422794.1 4287071 D 440085 CDS YP_002422795.1 218531979 7114373 4287793..4289268 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mex:Mext_3773 ATPase domain-containing protein; histidine kinase 4289268 7114373 Mchl_4067 Methylobacterium extorquens CM4 histidine kinase YP_002422795.1 4287793 D 440085 CDS YP_002422796.1 218531980 7114374 4289469..4290641 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3774 diguanylate cyclase; diguanylate cyclase 4290641 7114374 Mchl_4068 Methylobacterium extorquens CM4 diguanylate cyclase YP_002422796.1 4289469 D 440085 CDS YP_002422797.1 218531981 7114375 complement(4290770..4291426) 1 NC_011757.1 KEGG: mex:Mext_3775 glutathione-S-transferase protein; glutathione-S-transferase protein 4291426 7114375 Mchl_4069 Methylobacterium extorquens CM4 glutathione-S-transferase protein YP_002422797.1 4290770 R 440085 CDS YP_002422798.1 218531982 7114376 4291777..4292991 1 NC_011757.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: mex:Mext_3776 polyhydroxyalkanoate depolymerase, intracellular; polyhydroxyalkanoate depolymerase, intracellular 4292991 7114376 Mchl_4070 Methylobacterium extorquens CM4 polyhydroxyalkanoate depolymerase, intracellular YP_002422798.1 4291777 D 440085 CDS YP_002422799.1 218531983 7114377 4293426..4293743 1 NC_011757.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4293743 rpsU 7114377 rpsU Methylobacterium extorquens CM4 30S ribosomal protein S21 YP_002422799.1 4293426 D 440085 CDS YP_002422800.1 218531984 7114378 complement(4293844..4294233) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_3778 response regulator receiver; response regulator receiver protein 4294233 7114378 Mchl_4072 Methylobacterium extorquens CM4 response regulator receiver protein YP_002422800.1 4293844 R 440085 CDS YP_002422801.1 218531985 7114379 4294513..4295298 1 NC_011757.1 PFAM: glutamine amidotransferase class-II; KEGG: mex:Mext_3779 glutamine amidotransferase class-II; class II glutamine amidotransferase 4295298 7114379 Mchl_4073 Methylobacterium extorquens CM4 class II glutamine amidotransferase YP_002422801.1 4294513 D 440085 CDS YP_002422802.1 218531986 7114380 4295449..4296240 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_3780 hypothetical protein; hypothetical protein 4296240 7114380 Mchl_4074 Methylobacterium extorquens CM4 hypothetical protein YP_002422802.1 4295449 D 440085 CDS YP_002422803.1 218531987 7114381 complement(4296269..4297315) 1 NC_011757.1 PFAM: MaoC domain protein dehydratase; KEGG: mex:Mext_3781 dehydratase; MaoC domain-containing protein dehydratase 4297315 7114381 Mchl_4075 Methylobacterium extorquens CM4 MaoC domain-containing protein dehydratase YP_002422803.1 4296269 R 440085 CDS YP_002422804.1 218531988 7114382 complement(4297511..4297801) 1 NC_011757.1 PFAM: protein of unknown function YGGT; KEGG: mex:Mext_3782 protein of unknown function YGGT; hypothetical protein 4297801 7114382 Mchl_4076 Methylobacterium extorquens CM4 hypothetical protein YP_002422804.1 4297511 R 440085 CDS YP_002422805.1 218531989 7114384 4298338..4298835 1 NC_011757.1 KEGG: mrd:Mrad2831_0261 GTP diphosphokinase; GTP diphosphokinase 4298835 7114384 Mchl_4077 Methylobacterium extorquens CM4 GTP diphosphokinase YP_002422805.1 4298338 D 440085 CDS YP_002422806.1 218531990 7114386 4299352..4300173 1 NC_011757.1 hypothetical protein 4300173 7114386 Mchl_4079 Methylobacterium extorquens CM4 hypothetical protein YP_002422806.1 4299352 D 440085 CDS YP_002422807.1 218531991 7114387 complement(4300326..4300658) 1 NC_011757.1 KEGG: mex:Mext_0184 hypothetical protein; hypothetical protein 4300658 7114387 Mchl_4080 Methylobacterium extorquens CM4 hypothetical protein YP_002422807.1 4300326 R 440085 CDS YP_002422808.1 218531992 7114388 complement(4300666..4300899) 1 NC_011757.1 KEGG: mpo:Mpop_2918 hypothetical protein; hypothetical protein 4300899 7114388 Mchl_4081 Methylobacterium extorquens CM4 hypothetical protein YP_002422808.1 4300666 R 440085 CDS YP_002422809.1 218531993 7114389 complement(4301007..4301792) 1 NC_011757.1 PFAM: Gp37Gp68 family protein; KEGG: bra:BRADO0295 phage protein GP37/Gp68; Gp37Gp68 family protein 4301792 7114389 Mchl_4082 Methylobacterium extorquens CM4 Gp37Gp68 family protein YP_002422809.1 4301007 R 440085 CDS YP_002422810.1 218531994 7114390 complement(4301804..4302907) 1 NC_011757.1 KEGG: nha:Nham_0599 hypothetical protein; hypothetical protein 4302907 7114390 Mchl_4083 Methylobacterium extorquens CM4 hypothetical protein YP_002422810.1 4301804 R 440085 CDS YP_002422811.1 218531995 7114391 complement(4303078..4303602) 1 NC_011757.1 KEGG: mpo:Mpop_2387 hypothetical protein; hypothetical protein 4303602 7114391 Mchl_4084 Methylobacterium extorquens CM4 hypothetical protein YP_002422811.1 4303078 R 440085 CDS YP_002422812.1 218531996 7114392 complement(4303595..4304056) 1 NC_011757.1 PFAM: ribonuclease H; KEGG: pmy:Pmen_2066 ribonuclease H; ribonuclease H 4304056 7114392 Mchl_4085 Methylobacterium extorquens CM4 ribonuclease H YP_002422812.1 4303595 R 440085 CDS YP_002422813.1 218531997 7114393 complement(4304134..4308228) 1 NC_011757.1 PFAM: transglycosylase; KEGG: ppu:PP_2287 phage internal core protein; transglycosylase 4308228 7114393 Mchl_4086 Methylobacterium extorquens CM4 transglycosylase YP_002422813.1 4304134 R 440085 CDS YP_002422814.1 218531998 7114394 complement(4308351..4309079) 1 NC_011757.1 KEGG: sme:SMc02328 hypothetical unknown protein; hypothetical protein 4309079 7114394 Mchl_4087 Methylobacterium extorquens CM4 hypothetical protein YP_002422814.1 4308351 R 440085 CDS YP_002422815.1 218531999 7114395 4309571..4310356 1 NC_011757.1 KEGG: cti:RALTA_B0264 hypothetical protein; hypothetical protein 4310356 7114395 Mchl_4088 Methylobacterium extorquens CM4 hypothetical protein YP_002422815.1 4309571 D 440085 CDS YP_002422816.1 218532000 7114397 complement(4310710..4310952) 1 NC_011757.1 KEGG: mrd:Mrad2831_2237 hypothetical protein; hypothetical protein 4310952 7114397 Mchl_4090 Methylobacterium extorquens CM4 hypothetical protein YP_002422816.1 4310710 R 440085 CDS YP_002422817.1 218532001 7114398 complement(4311213..4311773) 1 NC_011757.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: mrd:Mrad2831_6517 resolvase domain-containing protein; Resolvase domain 4311773 7114398 Mchl_4091 Methylobacterium extorquens CM4 Resolvase domain YP_002422817.1 4311213 R 440085 CDS YP_002422818.1 218532002 7114399 4312114..4312599 1 NC_011757.1 KEGG: mpo:Mpop_0095 response regulator receiver protein; response regulator receiver protein 4312599 7114399 Mchl_4092 Methylobacterium extorquens CM4 response regulator receiver protein YP_002422818.1 4312114 D 440085 CDS YP_002422819.1 218532003 7114400 4312766..4313050 1 NC_011757.1 KEGG: mrd:Mrad2831_1399 lipoprotein; lipoprotein 4313050 7114400 Mchl_4093 Methylobacterium extorquens CM4 lipoprotein YP_002422819.1 4312766 D 440085 CDS YP_002422820.1 218532004 7114401 4313347..4313865 1 NC_011757.1 PFAM: HMG-I and HMG-Y DNA-binding domain protein; KEGG: mex:Mext_3719 hypothetical protein; HMG-I and HMG-Y DNA-binding domain-containing protein 4313865 7114401 Mchl_4094 Methylobacterium extorquens CM4 HMG-I and HMG-Y DNA-binding domain-containing protein YP_002422820.1 4313347 D 440085 CDS YP_002422821.1 218532005 7114402 complement(4314317..4314640) 1 NC_011757.1 KEGG: mex:Mext_3720 hypothetical protein; hypothetical protein 4314640 7114402 Mchl_4095 Methylobacterium extorquens CM4 hypothetical protein YP_002422821.1 4314317 R 440085 CDS YP_002422822.1 218532006 7114403 4316900..4317082 1 NC_011757.1 KEGG: mex:Mext_3718 hypothetical protein; hypothetical protein 4317082 7114403 Mchl_4096 Methylobacterium extorquens CM4 hypothetical protein YP_002422822.1 4316900 D 440085 CDS YP_002422823.1 218532007 7114404 complement(4317113..4318507) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mpo:Mpop_2395 integrase family protein; integrase family protein 4318507 7114404 Mchl_4097 Methylobacterium extorquens CM4 integrase family protein YP_002422823.1 4317113 R 440085 CDS YP_002422824.1 218532008 7114405 4318726..4320495 1 NC_011757.1 PFAM: integrase family protein; KEGG: rsp:RSP_2361 integrase/resolvase recombinase protein phage-related integrase; integrase family protein 4320495 7114405 Mchl_4098 Methylobacterium extorquens CM4 integrase family protein YP_002422824.1 4318726 D 440085 CDS YP_002422825.1 218532009 7114406 4320542..4321582 1 NC_011757.1 KEGG: shl:Shal_4055 hypothetical protein; hypothetical protein 4321582 7114406 Mchl_4099 Methylobacterium extorquens CM4 hypothetical protein YP_002422825.1 4320542 D 440085 CDS YP_002422826.1 218532010 7114407 4323013..4323855 1 NC_011757.1 PFAM: protein of unknown function DUF344; KEGG: mex:Mext_1138 hypothetical protein; hypothetical protein 4323855 7114407 Mchl_4100 Methylobacterium extorquens CM4 hypothetical protein YP_002422826.1 4323013 D 440085 CDS YP_002422827.1 218532011 7114408 4323907..4324224 1 NC_011757.1 KEGG: mex:Mext_1135 hypothetical protein; hypothetical protein 4324224 7114408 Mchl_4101 Methylobacterium extorquens CM4 hypothetical protein YP_002422827.1 4323907 D 440085 CDS YP_002422828.1 218532012 7114410 4324920..4326575 1 NC_011757.1 PFAM: sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: mex:Mext_0049 sulfate transporter; sulfate transporter 4326575 7114410 Mchl_4103 Methylobacterium extorquens CM4 sulfate transporter YP_002422828.1 4324920 D 440085 CDS YP_002422829.1 218532013 7114411 complement(4327088..4327453) 1 NC_011757.1 KEGG: mex:Mext_4255 hypothetical protein; hypothetical protein 4327453 7114411 Mchl_4104 Methylobacterium extorquens CM4 hypothetical protein YP_002422829.1 4327088 R 440085 CDS YP_002422830.1 218532014 7114412 4328340..4329512 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: met:M446_0110 alcohol dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 4329512 7114412 Mchl_4105 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES domain-containing protein YP_002422830.1 4328340 D 440085 CDS YP_002422831.1 218532015 7114413 4329584..4330189 1 NC_011757.1 KEGG: met:M446_0111 hypothetical protein; hypothetical protein 4330189 7114413 Mchl_4106 Methylobacterium extorquens CM4 hypothetical protein YP_002422831.1 4329584 D 440085 CDS YP_002422832.1 218532016 7114414 4330212..4331309 1 NC_011757.1 KEGG: met:M446_0112 hypothetical protein; hypothetical protein 4331309 7114414 Mchl_4107 Methylobacterium extorquens CM4 hypothetical protein YP_002422832.1 4330212 D 440085 CDS YP_002422833.1 218532017 7114415 4331977..4332585 1 NC_011757.1 KEGG: mex:Mext_4257 hypothetical protein; hypothetical protein 4332585 7114415 Mchl_4108 Methylobacterium extorquens CM4 hypothetical protein YP_002422833.1 4331977 D 440085 CDS YP_002422834.1 218532018 7114416 4332729..4332986 1 NC_011757.1 KEGG: mex:Mext_4256 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4332986 7114416 Mchl_4109 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002422834.1 4332729 D 440085 CDS YP_002422835.1 218532019 7114417 4333052..4334149 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_0043 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 4334149 7114417 Mchl_4110 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002422835.1 4333052 D 440085 CDS YP_002422836.1 218532020 7114418 4334146..4334376 1 NC_011757.1 KEGG: mex:Mext_0042 hypothetical protein; hypothetical protein 4334376 7114418 Mchl_4111 Methylobacterium extorquens CM4 hypothetical protein YP_002422836.1 4334146 D 440085 CDS YP_002422837.1 218532021 7114419 complement(4334529..4336250) 1 NC_011757.1 KEGG: mex:Mext_0123 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 4336250 7114419 Mchl_4112 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002422837.1 4334529 R 440085 CDS YP_002422838.1 218532022 7114420 4337237..4337947 1 NC_011757.1 KEGG: mmr:Mmar10_0158 hypothetical protein; hypothetical protein 4337947 7114420 Mchl_4113 Methylobacterium extorquens CM4 hypothetical protein YP_002422838.1 4337237 D 440085 CDS YP_002422839.1 218532023 7114421 complement(4338127..4338948) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3791 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4338948 7114421 Mchl_4114 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422839.1 4338127 R 440085 CDS YP_002422840.1 218532024 7114422 complement(4339141..4339440) 1 NC_011757.1 KEGG: mex:Mext_3792 hypothetical protein; hypothetical protein 4339440 7114422 Mchl_4115 Methylobacterium extorquens CM4 hypothetical protein YP_002422840.1 4339141 R 440085 CDS YP_002422841.1 218532025 7114423 4339667..4340116 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_3793 regulatory protein MarR; MarR family transcriptional regulator 4340116 7114423 Mchl_4116 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002422841.1 4339667 D 440085 CDS YP_002422842.1 218532026 7114424 complement(4340192..4340488) 1 NC_011757.1 KEGG: mex:Mext_3794 DoxX family protein; DoxX family protein 4340488 7114424 Mchl_4117 Methylobacterium extorquens CM4 DoxX family protein YP_002422842.1 4340192 R 440085 CDS YP_002422843.1 218532027 7114425 complement(4340599..4342005) 1 NC_011757.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mex:Mext_3795 MATE efflux family protein; MATE efflux family protein 4342005 7114425 Mchl_4118 Methylobacterium extorquens CM4 MATE efflux family protein YP_002422843.1 4340599 R 440085 CDS YP_002422844.1 218532028 7114426 complement(4342039..4342395) 1 NC_011757.1 KEGG: mex:Mext_3796 hypothetical protein; hypothetical protein 4342395 7114426 Mchl_4119 Methylobacterium extorquens CM4 hypothetical protein YP_002422844.1 4342039 R 440085 CDS YP_002422845.1 218532029 7114427 complement(4342559..4343101) 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_3797 regulatory protein TetR; TetR family transcriptional regulator 4343101 7114427 Mchl_4120 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002422845.1 4342559 R 440085 CDS YP_002422846.1 218532030 7114428 complement(4343341..4346448) 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_3798 acriflavin resistance protein; acriflavin resistance protein 4346448 7114428 Mchl_4121 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002422846.1 4343341 R 440085 CDS YP_002422847.1 218532031 7114429 complement(4346445..4347530) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3799 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4347530 7114429 Mchl_4122 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422847.1 4346445 R 440085 CDS YP_002422848.1 218532032 7114430 4347709..4347969 1 NC_011757.1 KEGG: azc:AZC_1282 hypothetical protein; hypothetical protein 4347969 7114430 Mchl_4123 Methylobacterium extorquens CM4 hypothetical protein YP_002422848.1 4347709 D 440085 CDS YP_002422849.1 218532033 7114433 4348721..4349140 1 NC_011757.1 KEGG: mex:Mext_3818 hypothetical protein; CopG/Arc/MetJ family transcriptional regulator 4349140 7114433 Mchl_4126 Methylobacterium extorquens CM4 CopG/Arc/MetJ family transcriptional regulator YP_002422849.1 4348721 D 440085 CDS YP_002422850.1 218532034 7114434 4349214..4350473 1 NC_011757.1 TIGRFAM: esterase, PHB depolymerase family; PFAM: esterase PHB depolymerase; KEGG: mex:Mext_3819 PHB depolymerase family esterase; esterase, PHB depolymerase family 4350473 7114434 Mchl_4127 Methylobacterium extorquens CM4 esterase, PHB depolymerase family YP_002422850.1 4349214 D 440085 CDS YP_002422851.1 218532035 7114436 complement(4350650..4351726) 1 NC_011757.1 PFAM: choloylglycine hydrolase; KEGG: mex:Mext_3821 choloylglycine hydrolase; choloylglycine hydrolase 4351726 7114436 Mchl_4129 Methylobacterium extorquens CM4 choloylglycine hydrolase YP_002422851.1 4350650 R 440085 CDS YP_002422852.1 218532036 7114437 4352193..4353098 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3822 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4353098 7114437 Mchl_4130 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422852.1 4352193 D 440085 CDS YP_002422853.1 218532037 7114438 complement(4353077..4353946) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_3823 LysR substrate-binding; LysR family transcriptional regulator 4353946 7114438 Mchl_4131 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422853.1 4353077 R 440085 CDS YP_002422854.1 218532038 7114439 4354044..4354262 1 NC_011757.1 KEGG: mpo:Mpop_0679 hypothetical protein; hypothetical protein 4354262 7114439 Mchl_4132 Methylobacterium extorquens CM4 hypothetical protein YP_002422854.1 4354044 D 440085 CDS YP_002422855.1 218532039 7114440 4354410..4355117 1 NC_011757.1 PFAM: protein of unknown function DUF1275; KEGG: mex:Mext_3824 hypothetical protein; hypothetical protein 4355117 7114440 Mchl_4133 Methylobacterium extorquens CM4 hypothetical protein YP_002422855.1 4354410 D 440085 CDS YP_002422856.1 218532040 7114441 4355564..4356367 1 NC_011757.1 PFAM: helix-turn-helix domain protein; GAF domain protein; KEGG: mex:Mext_3825 GAF domain-containing protein; XRE family transcriptional regulator 4356367 7114441 Mchl_4134 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002422856.1 4355564 D 440085 CDS YP_002422857.1 218532041 7114442 4356498..4358195 1 NC_011757.1 KEGG: mex:Mext_3826 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 4358195 7114442 Mchl_4135 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor YP_002422857.1 4356498 D 440085 CDS YP_002422858.1 218532042 7114443 4358530..4360020 1 NC_011757.1 KEGG: mex:Mext_3827 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 4360020 7114443 Mchl_4136 Methylobacterium extorquens CM4 protease Do YP_002422858.1 4358530 D 440085 CDS YP_002422859.1 218532043 7114444 4360684..4361043 1 NC_011757.1 inactive form; acid-resistance protein 4361043 7114444 Mchl_4137 Methylobacterium extorquens CM4 acid-resistance protein YP_002422859.1 4360684 D 440085 CDS YP_002422860.1 218532044 7114445 complement(4361588..4362955) 1 NC_011757.1 PFAM: chloride channel core; KEGG: mex:Mext_3829 chloride channel core; chloride channel core 4362955 7114445 Mchl_4138 Methylobacterium extorquens CM4 chloride channel core YP_002422860.1 4361588 R 440085 CDS YP_002422861.1 218532045 7114446 complement(4363083..4366214) 1 NC_011757.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_5127 transporter hydrophobe/amphiphile efflux-1 (HAE1) family; hydrophobe/amphiphile efflux-1 (HAE1) family transporter 4366214 7114446 Mchl_4139 Methylobacterium extorquens CM4 hydrophobe/amphiphile efflux-1 (HAE1) family transporter YP_002422861.1 4363083 R 440085 CDS YP_002422862.1 218532046 7115103 complement(4366322..4367632) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3832 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4367632 7115103 Mchl_4140 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422862.1 4366322 R 440085 CDS YP_002422863.1 218532047 7115266 complement(4367699..4367932) 1 NC_011757.1 hypothetical protein 4367932 7115266 Mchl_4141 Methylobacterium extorquens CM4 hypothetical protein YP_002422863.1 4367699 R 440085 CDS YP_002422864.1 218532048 7115267 complement(4368469..4369479) 1 NC_011757.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: mex:Mext_3833 cytochrome d ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 4369479 7115267 Mchl_4142 Methylobacterium extorquens CM4 cytochrome d ubiquinol oxidase subunit II YP_002422864.1 4368469 R 440085 CDS YP_002422865.1 218532049 7115268 complement(4369494..4370918) 1 NC_011757.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: mex:Mext_3834 cytochrome bd ubiquinol oxidase subunit I; cytochrome bd ubiquinol oxidase subunit I 4370918 7115268 Mchl_4143 Methylobacterium extorquens CM4 cytochrome bd ubiquinol oxidase subunit I YP_002422865.1 4369494 R 440085 CDS YP_002422866.1 218532050 7115269 complement(4371164..4371946) 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_3835 hypothetical protein; hypothetical protein 4371946 7115269 Mchl_4144 Methylobacterium extorquens CM4 hypothetical protein YP_002422866.1 4371164 R 440085 CDS YP_002422867.1 218532051 7115270 complement(4371943..4372371) 1 NC_011757.1 PFAM: regulatory protein ArsR; KEGG: mex:Mext_3836 regulatory protein ArsR; ArsR family transcriptional regulator 4372371 7115270 Mchl_4145 Methylobacterium extorquens CM4 ArsR family transcriptional regulator YP_002422867.1 4371943 R 440085 CDS YP_002422868.1 218532052 7115271 complement(4372368..4373261) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_3837 beta-lactamase domain-containing protein; beta-lactamase 4373261 7115271 Mchl_4146 Methylobacterium extorquens CM4 beta-lactamase YP_002422868.1 4372368 R 440085 CDS YP_002422869.1 218532053 7115272 complement(4373264..4373929) 1 NC_011757.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: mex:Mext_3838 peroxiredoxin; peroxiredoxin 4373929 7115272 Mchl_4147 Methylobacterium extorquens CM4 peroxiredoxin YP_002422869.1 4373264 R 440085 CDS YP_002422870.1 218532054 7115273 4374056..4375729 1 NC_011757.1 PFAM: protein of unknown function DUF442; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_3839 hypothetical protein; hypothetical protein 4375729 7115273 Mchl_4148 Methylobacterium extorquens CM4 hypothetical protein YP_002422870.1 4374056 D 440085 CDS YP_002422871.1 218532055 7115274 4375978..4377096 1 NC_011757.1 KEGG: mex:Mext_3840 tetratricopeptide TPR_4; tetratricopeptide TPR_4 4377096 7115274 Mchl_4149 Methylobacterium extorquens CM4 tetratricopeptide TPR_4 YP_002422871.1 4375978 D 440085 CDS YP_002422872.1 218532056 7115275 complement(4377170..4378036) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3841 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4378036 7115275 Mchl_4150 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422872.1 4377170 R 440085 CDS YP_002422873.1 218532057 7115276 4378203..4379252 1 NC_011757.1 PFAM: periplasmic binding protein; KEGG: mex:Mext_3842 periplasmic binding protein; periplasmic binding protein 4379252 7115276 Mchl_4151 Methylobacterium extorquens CM4 periplasmic binding protein YP_002422873.1 4378203 D 440085 CDS YP_002422874.1 218532058 7115277 4379249..4380298 1 NC_011757.1 PFAM: transporter permease; ABC-3 protein; KEGG: mex:Mext_3843 transporter permease; transporter permease 4380298 7115277 Mchl_4152 Methylobacterium extorquens CM4 transporter permease YP_002422874.1 4379249 D 440085 CDS YP_002422875.1 218532059 7115278 4380295..4381068 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3844 ABC transporter; ABC transporter 4381068 7115278 Mchl_4153 Methylobacterium extorquens CM4 ABC transporter YP_002422875.1 4380295 D 440085 CDS YP_002422876.1 218532060 7115279 complement(4381078..4381821) 1 NC_011757.1 PFAM: oxidoreductase molybdopterin binding; KEGG: mex:Mext_3845 oxidoreductase molybdopterin binding; molybdopterin binding oxidoreductase 4381821 7115279 Mchl_4154 Methylobacterium extorquens CM4 molybdopterin binding oxidoreductase YP_002422876.1 4381078 R 440085 CDS YP_002422877.1 218532061 7115280 complement(4381818..4382546) 1 NC_011757.1 KEGG: mex:Mext_3846 hypothetical protein; hypothetical protein 4382546 7115280 Mchl_4155 Methylobacterium extorquens CM4 hypothetical protein YP_002422877.1 4381818 R 440085 CDS YP_002422878.1 218532062 7115281 complement(4382560..4383156) 1 NC_011757.1 PFAM: NodS family protein; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_3847 methyltransferase type 12; type 12 methyltransferase 4383156 7115281 Mchl_4156 Methylobacterium extorquens CM4 type 12 methyltransferase YP_002422878.1 4382560 R 440085 CDS YP_002422879.1 218532063 7115282 complement(4383153..4384328) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_3848 acyl-CoA dehydrogenase type 2; acyl-CoA dehydrogenase type 2 domain-containing protein 4384328 7115282 Mchl_4157 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase type 2 domain-containing protein YP_002422879.1 4383153 R 440085 CDS YP_002422880.1 218532064 7115283 4384569..4384856 1 NC_011757.1 KEGG: mex:Mext_3849 hypothetical protein; hypothetical protein 4384856 7115283 Mchl_4158 Methylobacterium extorquens CM4 hypothetical protein YP_002422880.1 4384569 D 440085 CDS YP_002422881.1 218532065 7115284 4384871..4385107 1 NC_011757.1 KEGG: mex:Mext_3850 hypothetical protein; hypothetical protein 4385107 7115284 Mchl_4159 Methylobacterium extorquens CM4 hypothetical protein YP_002422881.1 4384871 D 440085 CDS YP_002422882.1 218532066 7115285 4385110..4385328 1 NC_011757.1 KEGG: mex:Mext_3851 hypothetical protein; hypothetical protein 4385328 7115285 Mchl_4160 Methylobacterium extorquens CM4 hypothetical protein YP_002422882.1 4385110 D 440085 CDS YP_002422883.1 218532067 7115286 complement(4385416..4386450) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_3852 aldo/keto reductase; aldo/keto reductase 4386450 7115286 Mchl_4161 Methylobacterium extorquens CM4 aldo/keto reductase YP_002422883.1 4385416 R 440085 CDS YP_002422884.1 218532068 7115287 4386763..4386990 1 NC_011757.1 KEGG: mex:Mext_3853 hypothetical protein; hypothetical protein 4386990 7115287 Mchl_4162 Methylobacterium extorquens CM4 hypothetical protein YP_002422884.1 4386763 D 440085 CDS YP_002422885.1 218532069 7115288 complement(4386996..4387595) 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_3854 isochorismatase hydrolase; isochorismatase hydrolase 4387595 7115288 Mchl_4163 Methylobacterium extorquens CM4 isochorismatase hydrolase YP_002422885.1 4386996 R 440085 CDS YP_002422886.1 218532070 7115289 complement(4387869..4389185) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3855 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4389185 7115289 Mchl_4164 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422886.1 4387869 R 440085 CDS YP_002422887.1 218532071 7115290 complement(4389178..4392408) 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_3856 acriflavin resistance protein; acriflavin resistance protein 4392408 7115290 Mchl_4165 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002422887.1 4389178 R 440085 CDS YP_002422888.1 218532072 7115291 complement(4392720..4394096) 1 NC_011757.1 KEGG: mex:Mext_3857 hypothetical protein; hypothetical protein 4394096 7115291 Mchl_4166 Methylobacterium extorquens CM4 hypothetical protein YP_002422888.1 4392720 R 440085 CDS YP_002422889.1 218532073 7115292 complement(4394093..4394830) 1 NC_011757.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_3858 NADP oxidoreductase coenzyme F420-dependent; NADP oxidoreductase coenzyme F420-dependent 4394830 7115292 Mchl_4167 Methylobacterium extorquens CM4 NADP oxidoreductase coenzyme F420-dependent YP_002422889.1 4394093 R 440085 CDS YP_002422890.1 218532074 7115293 complement(4394820..4395749) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_3859 aldo/keto reductase; aldo/keto reductase 4395749 7115293 Mchl_4168 Methylobacterium extorquens CM4 aldo/keto reductase YP_002422890.1 4394820 R 440085 CDS YP_002422891.1 218532075 7115294 complement(4395822..4396376) 1 NC_011757.1 TIGRFAM: methyltransferase; PFAM: protein of unknown function methylase KEGG: mex:Mext_3860 methyltransferase; methyltransferase 4396376 7115294 Mchl_4169 Methylobacterium extorquens CM4 methyltransferase YP_002422891.1 4395822 R 440085 CDS YP_002422892.1 218532076 7115295 complement(4396389..4398413) 1 NC_011757.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: mex:Mext_3861 RNA-binding S4 domain-containing protein; RNA-binding S4 domain-containing protein 4398413 7115295 Mchl_4170 Methylobacterium extorquens CM4 RNA-binding S4 domain-containing protein YP_002422892.1 4396389 R 440085 CDS YP_002422893.1 218532077 7115296 complement(4398504..4398680) 1 NC_011757.1 PFAM: protein of unknown function DUF1328; KEGG: mex:Mext_3862 hypothetical protein; hypothetical protein 4398680 7115296 Mchl_4171 Methylobacterium extorquens CM4 hypothetical protein YP_002422893.1 4398504 R 440085 CDS YP_002422894.1 218532078 7115297 complement(4398848..4399615) 1 NC_011757.1 TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_3863 arsenical resistance protein ArsH; arsenical resistance protein ArsH 4399615 7115297 Mchl_4172 Methylobacterium extorquens CM4 arsenical resistance protein ArsH YP_002422894.1 4398848 R 440085 CDS YP_002422895.1 218532079 7115298 4399666..4400025 1 NC_011757.1 SMART: regulatory protein ArsR; KEGG: mex:Mext_3864 regulatory protein ArsR; ArsR family transcriptional regulator 4400025 7115298 Mchl_4173 Methylobacterium extorquens CM4 ArsR family transcriptional regulator YP_002422895.1 4399666 D 440085 CDS YP_002422896.1 218532080 7115299 4400018..4400455 1 NC_011757.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: mex:Mext_3865 arsenate reductase; arsenate reductase 4400455 7115299 Mchl_4174 Methylobacterium extorquens CM4 arsenate reductase YP_002422896.1 4400018 D 440085 CDS YP_002422897.1 218532081 7115300 4400465..4401541 1 NC_011757.1 TIGRFAM: arsenic resistance protein; PFAM: Bile acid:sodium symporter; KEGG: mex:Mext_3866 arsenic resistance protein; arsenic resistance protein 4401541 7115300 Mchl_4175 Methylobacterium extorquens CM4 arsenic resistance protein YP_002422897.1 4400465 D 440085 CDS YP_002422898.1 218532082 7115301 complement(4401739..4403841) 1 NC_011757.1 KEGG: mex:Mext_3867 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 4403841 7115301 Mchl_4176 Methylobacterium extorquens CM4 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_002422898.1 4401739 R 440085 CDS YP_002422899.1 218532083 7115302 4404145..4405062 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_3868 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4405062 7115302 Mchl_4177 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002422899.1 4404145 D 440085 CDS YP_002422900.1 218532084 7115303 complement(4405067..4405768) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3869 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4405768 7115303 Mchl_4178 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002422900.1 4405067 R 440085 CDS YP_002422901.1 218532085 7115304 complement(4405860..4406303) 1 NC_011757.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: mex:Mext_3870 CMP/dCMP deaminase zinc-binding; zinc-binding CMP/dCMP deaminase 4406303 7115304 Mchl_4179 Methylobacterium extorquens CM4 zinc-binding CMP/dCMP deaminase YP_002422901.1 4405860 R 440085 CDS YP_002422902.1 218532086 7115305 complement(4406317..4407624) 1 NC_011757.1 KEGG: mex:Mext_3871 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; phosphoribosylamine/glycine ligase 4407624 7115305 Mchl_4180 Methylobacterium extorquens CM4 phosphoribosylamine/glycine ligase YP_002422902.1 4406317 R 440085 CDS YP_002422903.1 218532087 7115306 4407708..4408445 1 NC_011757.1 KEGG: mex:Mext_3872 hypothetical protein; hypothetical protein 4408445 7115306 Mchl_4181 Methylobacterium extorquens CM4 hypothetical protein YP_002422903.1 4407708 D 440085 CDS YP_002422904.1 218532088 7115307 4408523..4408747 1 NC_011757.1 KEGG: mpo:Mpop_4329 hypothetical protein; hypothetical protein 4408747 7115307 Mchl_4182 Methylobacterium extorquens CM4 hypothetical protein YP_002422904.1 4408523 D 440085 CDS YP_002422905.1 218532089 7115308 4408972..4410543 1 NC_011757.1 KEGG: mex:Mext_3873 exodeoxyribonuclease VII large subunit; TIGRFAM: exodeoxyribonuclease VII large subunit; PFAM: exonuclease VII large subunit; nucleic acid binding OB-fold tRNA/helicase-type; exodeoxyribonuclease VII large subunit 4410543 7115308 Mchl_4183 Methylobacterium extorquens CM4 exodeoxyribonuclease VII large subunit YP_002422905.1 4408972 D 440085 CDS YP_002422906.1 218532090 7115309 4410688..4410915 1 NC_011757.1 KEGG: mex:Mext_3874 hypothetical protein; hypothetical protein 4410915 7115309 Mchl_4184 Methylobacterium extorquens CM4 hypothetical protein YP_002422906.1 4410688 D 440085 CDS YP_002422907.1 218532091 7115310 4411083..4412027 1 NC_011757.1 KEGG: mex:Mext_3875 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; ribose-phosphate pyrophosphokinase 4412027 7115310 Mchl_4185 Methylobacterium extorquens CM4 ribose-phosphate pyrophosphokinase YP_002422907.1 4411083 D 440085 CDS YP_002422908.1 218532092 7115311 complement(4412149..4412613) 1 NC_011757.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: mex:Mext_3876 transcription elongation factor GreA/GreB domain-containing protein; GreA/GreB family elongation factor 4412613 7115311 Mchl_4186 Methylobacterium extorquens CM4 GreA/GreB family elongation factor YP_002422908.1 4412149 R 440085 CDS YP_002422909.1 218532093 7115312 complement(4412634..4413632) 1 NC_011757.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_3877 quinone oxidoreductase; YhdH/YhfP family quinone oxidoreductase 4413632 7115312 Mchl_4187 Methylobacterium extorquens CM4 YhdH/YhfP family quinone oxidoreductase YP_002422909.1 4412634 R 440085 CDS YP_002422910.1 218532094 7115313 complement(4413738..4414334) 1 NC_011757.1 KEGG: mex:Mext_3878 hypothetical protein; hypothetical protein 4414334 7115313 Mchl_4188 Methylobacterium extorquens CM4 hypothetical protein YP_002422910.1 4413738 R 440085 CDS YP_002422911.1 218532095 7115314 4414813..4415151 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mex:Mext_3879 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 4415151 7115314 Mchl_4189 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002422911.1 4414813 D 440085 CDS YP_002422912.1 218532096 7115315 4415670..4416260 1 NC_011757.1 PFAM: transcription factor CarD; KEGG: mex:Mext_3880 transcription factor CarD; CarD family transcriptional regulator 4416260 7115315 Mchl_4190 Methylobacterium extorquens CM4 CarD family transcriptional regulator YP_002422912.1 4415670 D 440085 CDS YP_002422913.1 218532097 7115316 4416543..4417415 1 NC_011757.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 4417415 rpoH2 7115316 rpoH2 Methylobacterium extorquens CM4 RNA polymerase factor sigma-32 YP_002422913.1 4416543 D 440085 CDS YP_002422914.1 218532098 7115317 complement(4417481..4418176) 1 NC_011757.1 KEGG: bpm:BURPS1710b_1763 hypothetical protein; hypothetical protein 4418176 7115317 Mchl_4192 Methylobacterium extorquens CM4 hypothetical protein YP_002422914.1 4417481 R 440085 CDS YP_002422915.1 218532099 7115320 complement(4418669..4420336) 1 NC_011757.1 PFAM: Resolvase domain; Recombinase; KEGG: nwi:Nwi_3138 resolvase; Resolvase domain 4420336 7115320 Mchl_4193 Methylobacterium extorquens CM4 Resolvase domain YP_002422915.1 4418669 R 440085 CDS YP_002422916.1 218532100 7115322 4421162..4421527 1 NC_011757.1 PFAM: protein of unknown function DUF971; KEGG: mrd:Mrad2831_6148 hypothetical protein; hypothetical protein 4421527 7115322 Mchl_4195 Methylobacterium extorquens CM4 hypothetical protein YP_002422916.1 4421162 D 440085 CDS YP_002422917.1 218532101 7115323 4421594..4423336 1 NC_011757.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; KEGG: mrd:Mrad2831_6149 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; oxidoreductase 4423336 7115323 Mchl_4196 Methylobacterium extorquens CM4 oxidoreductase YP_002422917.1 4421594 D 440085 CDS YP_002422918.1 218532102 7115324 4423378..4423611 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mrd:Mrad2831_6150 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 4423611 7115324 Mchl_4197 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002422918.1 4423378 D 440085 CDS YP_002422919.1 218532103 7115325 4423622..4424587 1 NC_011757.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein; KEGG: mrd:Mrad2831_6151 heat repeat-containing PBS lyase; HEAT domain-containing protein 4424587 7115325 Mchl_4198 Methylobacterium extorquens CM4 HEAT domain-containing protein YP_002422919.1 4423622 D 440085 CDS YP_002422920.1 218532104 7115326 4424739..4425521 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mrd:Mrad2831_6152 Crp/FNR family transcriptional regulator; cyclic nucleotide-binding protein 4425521 7115326 Mchl_4199 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002422920.1 4424739 D 440085 CDS YP_002422921.1 218532105 7115327 4425685..4427112 1 NC_011757.1 KEGG: mrd:Mrad2831_6153 ABC transporter substrate-binding protein; ABC transporter substrate-binding protein 4427112 7115327 Mchl_4200 Methylobacterium extorquens CM4 ABC transporter substrate-binding protein YP_002422921.1 4425685 D 440085 CDS YP_002422922.1 218532106 7115328 4427112..4428029 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mrd:Mrad2831_6154 binding-protein-dependent transporters inner membrane component; binding-protein-dependent transporters inner membrane component 4428029 7115328 Mchl_4201 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002422922.1 4427112 D 440085 CDS YP_002422923.1 218532107 7115329 4428077..4428937 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mrd:Mrad2831_6155 ABC transporter; ABC transporter 4428937 7115329 Mchl_4202 Methylobacterium extorquens CM4 ABC transporter YP_002422923.1 4428077 D 440085 CDS YP_002422924.1 218532108 7115330 4429045..4429383 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mrd:Mrad2831_6156 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 4429383 7115330 Mchl_4203 Methylobacterium extorquens CM4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_002422924.1 4429045 D 440085 CDS YP_002422925.1 218532109 7115331 4429411..4430184 1 NC_011757.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: mpo:Mpop_2286 oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain-containing protein 4430184 7115331 Mchl_4204 Methylobacterium extorquens CM4 oxidoreductase FAD/NAD(P)-binding domain-containing protein YP_002422925.1 4429411 D 440085 CDS YP_002422926.1 218532110 7115332 4430362..4430589 1 NC_011757.1 KEGG: mpo:Mpop_0212 hypothetical protein; hypothetical protein 4430589 7115332 Mchl_4205 Methylobacterium extorquens CM4 hypothetical protein YP_002422926.1 4430362 D 440085 CDS YP_002422927.1 218532111 7115333 complement(4430648..4431553) 1 NC_011757.1 PFAM: CoA-binding protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: rpe:RPE_3202 succinyl-CoA synthetase, alpha subunit; CoA-binding protein 4431553 7115333 Mchl_4206 Methylobacterium extorquens CM4 CoA-binding protein YP_002422927.1 4430648 R 440085 CDS YP_002422928.1 218532112 7115334 complement(4431550..4432704) 1 NC_011757.1 PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: rpe:RPE_3203 succinate--CoA ligase (ADP-forming); succinate--CoA ligase 4432704 7115334 Mchl_4207 Methylobacterium extorquens CM4 succinate--CoA ligase YP_002422928.1 4431550 R 440085 CDS YP_002422929.1 218532113 7115335 complement(4432701..4434143) 1 NC_011757.1 PFAM: aldehyde dehydrogenase; KEGG: rpe:RPE_3204 hypothetical protein; aldehyde dehydrogenase 4434143 7115335 Mchl_4208 Methylobacterium extorquens CM4 aldehyde dehydrogenase YP_002422929.1 4432701 R 440085 CDS YP_002422930.1 218532114 7115336 complement(4434204..4435511) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: pde:Pden_1011 major facilitator superfamily MFS_1; major facilitator superfamily protein 4435511 7115336 Mchl_4209 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422930.1 4434204 R 440085 CDS YP_002422931.1 218532115 7115337 4436045..4436257 1 NC_011757.1 hypothetical protein 4436257 7115337 Mchl_4210 Methylobacterium extorquens CM4 hypothetical protein YP_002422931.1 4436045 D 440085 CDS YP_002422932.1 218532116 7115338 4436675..4438354 1 NC_011757.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: cti:RALTA_B1541 choline dehydrogenase, a flavoprotein; glucose-methanol-choline oxidoreductase 4438354 7115338 Mchl_4211 Methylobacterium extorquens CM4 glucose-methanol-choline oxidoreductase YP_002422932.1 4436675 D 440085 CDS YP_002422933.1 218532117 7115339 4438351..4439727 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: cti:RALTA_B1542 shikimate and dehydroshikimate transporter (); MFS family transporter; major facilitator superfamily protein 4439727 7115339 Mchl_4212 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002422933.1 4438351 D 440085 CDS YP_002422934.1 218532118 7115340 4439820..4440890 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mpo:Mpop_0213 hypothetical protein; hypothetical protein 4440890 7115340 Mchl_4213 Methylobacterium extorquens CM4 hypothetical protein YP_002422934.1 4439820 D 440085 CDS YP_002422935.1 218532119 7115341 complement(4441041..4442816) 1 NC_011757.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source; sulfoacetaldehyde acetyltransferase 4442816 7115341 Mchl_4214 Methylobacterium extorquens CM4 sulfoacetaldehyde acetyltransferase YP_002422935.1 4441041 R 440085 CDS YP_002422936.1 218532120 7115342 4442985..4443761 1 NC_011757.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; KEGG: reu:Reut_B3754 regulatory protein, IclR; IclR family transcriptional regulator 4443761 7115342 Mchl_4215 Methylobacterium extorquens CM4 IclR family transcriptional regulator YP_002422936.1 4442985 D 440085 CDS YP_002422937.1 218532121 7115343 4443797..4444966 1 NC_011757.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: met:M446_6098 acetate kinase; acetate kinase 4444966 7115343 Mchl_4216 Methylobacterium extorquens CM4 acetate kinase YP_002422937.1 4443797 D 440085 CDS YP_002422938.1 218532122 7115344 complement(4444981..4445343) 1 NC_011757.1 KEGG: bpt:Bpet3233 hypothetical protein; hypothetical protein 4445343 7115344 Mchl_4217 Methylobacterium extorquens CM4 hypothetical protein YP_002422938.1 4444981 R 440085 CDS YP_002422939.1 218532123 7115345 complement(4445343..4446566) 1 NC_011757.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: sme:SMc04049 sulfite oxidase protein; molybdopterin binding oxidoreductase 4446566 7115345 Mchl_4218 Methylobacterium extorquens CM4 molybdopterin binding oxidoreductase YP_002422939.1 4445343 R 440085 CDS YP_002422940.1 218532124 7115346 complement(4446662..4448188) 1 NC_011757.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: jan:Jann_1159 hypothetical protein; hypothetical protein 4448188 7115346 Mchl_4219 Methylobacterium extorquens CM4 hypothetical protein YP_002422940.1 4446662 R 440085 CDS YP_002422941.1 218532125 7117371 complement(4448207..4448767) 1 NC_011757.1 KEGG: tfu:Tfu_1713 hypothetical protein; hypothetical protein 4448767 7117371 Mchl_4220 Methylobacterium extorquens CM4 hypothetical protein YP_002422941.1 4448207 R 440085 CDS YP_002422942.1 218532126 7117455 complement(4448769..4449725) 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: tle:Tlet_1456 uncharacterized protein UPF0065; hypothetical protein 4449725 7117455 Mchl_4221 Methylobacterium extorquens CM4 hypothetical protein YP_002422942.1 4448769 R 440085 CDS YP_002422943.1 218532127 7117456 4449862..4450743 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rpb:RPB_2839 LysR family transcriptional regulator; LysR family transcriptional regulator 4450743 7117456 Mchl_4222 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002422943.1 4449862 D 440085 CDS YP_002422944.1 218532128 7117460 4451535..4452647 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mxa:MXAN_1042 glycosyl transferase, group 1 family protein; group 1 glycosyl transferase 4452647 7117460 Mchl_4226 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002422944.1 4451535 D 440085 CDS YP_002422945.1 218532129 7117462 4454091..4455293 1 NC_011757.1 PFAM: polysaccharide biosynthesis protein; KEGG: psa:PST_2496 hypothetical protein; polysaccharide biosynthesis protein 4455293 7117462 Mchl_4228 Methylobacterium extorquens CM4 polysaccharide biosynthesis protein YP_002422945.1 4454091 D 440085 CDS YP_002422946.1 218532130 7117467 complement(4458373..4459254) 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: tbd:Tbd_0898 hypothetical protein; type 11 methyltransferase 4459254 7117467 Mchl_4233 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002422946.1 4458373 R 440085 CDS YP_002422947.1 218532131 7117470 4461544..4462032 1 NC_011757.1 KEGG: GI23660 gene product from transcript GI23660-RA; hypothetical protein 4462032 7117470 Mchl_4236 Methylobacterium extorquens CM4 hypothetical protein YP_002422947.1 4461544 D 440085 CDS YP_002422948.1 218532132 7117471 4462032..4463993 1 NC_011757.1 PFAM: glycoside hydrolase family 5; KEGG: azc:AZC_1128 hypothetical protein; glycoside hydrolase family protein 4463993 7117471 Mchl_4237 Methylobacterium extorquens CM4 glycoside hydrolase family protein YP_002422948.1 4462032 D 440085 CDS YP_002422949.1 218532133 7117473 complement(4464710..4465372) 1 NC_011757.1 PFAM: sugar transferase; KEGG: bid:Bind_1034 undecaprenyl-phosphate glucose phosphotransferase; sugar transferase 4465372 7117473 Mchl_4239 Methylobacterium extorquens CM4 sugar transferase YP_002422949.1 4464710 R 440085 CDS YP_002422950.1 218532134 7117477 complement(4468064..4469326) 1 NC_011757.1 hypothetical protein 4469326 7117477 Mchl_4243 Methylobacterium extorquens CM4 hypothetical protein YP_002422950.1 4468064 R 440085 CDS YP_002422951.1 218532135 7117481 complement(4472138..4473457) 1 NC_011757.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: bra:BRADO4751 hypothetical protein; lipopolysaccharide biosynthesis protein 4473457 7117481 Mchl_4247 Methylobacterium extorquens CM4 lipopolysaccharide biosynthesis protein YP_002422951.1 4472138 R 440085 CDS YP_002422952.1 218532136 7117482 complement(4473483..4474700) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: oan:Oant_0391 glycosyl transferase group 1; group 1 glycosyl transferase 4474700 7117482 Mchl_4248 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002422952.1 4473483 R 440085 CDS YP_002422953.1 218532137 7117483 complement(4474725..4475846) 1 NC_011757.1 PFAM: glycosyl transferase group 1; protein of unknown function DUF1972; KEGG: met:M446_1455 polysaccharide export protein; hypothetical protein 4475846 7117483 Mchl_4249 Methylobacterium extorquens CM4 hypothetical protein YP_002422953.1 4474725 R 440085 CDS YP_002422954.1 218532138 7117484 complement(4475916..4477082) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mae:Maeo_0395 glycosyl transferase group 1; group 1 glycosyl transferase 4477082 7117484 Mchl_4250 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002422954.1 4475916 R 440085 CDS YP_002422955.1 218532139 7117485 complement(4477840..4478094) 1 NC_011757.1 hypothetical protein 4478094 7117485 Mchl_4251 Methylobacterium extorquens CM4 hypothetical protein YP_002422955.1 4477840 R 440085 CDS YP_002422956.1 218532140 7117486 complement(4481038..4481436) 1 NC_011757.1 KEGG: met:M446_1177 integrase family protein; integrase family protein 4481436 7117486 Mchl_4252 Methylobacterium extorquens CM4 integrase family protein YP_002422956.1 4481038 R 440085 CDS YP_002422957.1 218532141 7117487 complement(4482078..4483502) 1 NC_011757.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 4483502 7117487 Mchl_4253 Methylobacterium extorquens CM4 tRNA (uracil-5-)-methyltransferase Gid YP_002422957.1 4482078 R 440085 CDS YP_002422958.1 218532142 7117488 4483796..4485418 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_3886 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 4485418 7117488 Mchl_4254 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002422958.1 4483796 D 440085 CDS YP_002422959.1 218532143 7117489 complement(4485457..4486431) 1 NC_011757.1 SMART: PDZ/DHR/GLGF domain protein; KEGG: mex:Mext_3887 PDZ/DHR/GLGF domain-containing protein; PDZ/DHR/GLGF domain-containing protein 4486431 7117489 Mchl_4255 Methylobacterium extorquens CM4 PDZ/DHR/GLGF domain-containing protein YP_002422959.1 4485457 R 440085 CDS YP_002422960.1 218532144 7117490 4486872..4487426 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_3888 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 4487426 7117490 Mchl_4256 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002422960.1 4486872 D 440085 CDS YP_002422961.1 218532145 7117491 4487423..4488202 1 NC_011757.1 KEGG: mex:Mext_3889 uncharacterized protein-like protein; hypothetical protein 4488202 7117491 Mchl_4257 Methylobacterium extorquens CM4 hypothetical protein YP_002422961.1 4487423 D 440085 CDS YP_002422962.1 218532146 7117492 complement(4488367..4489308) 1 NC_011757.1 KEGG: mex:Mext_3890 hypothetical protein; hypothetical protein 4489308 7117492 Mchl_4258 Methylobacterium extorquens CM4 hypothetical protein YP_002422962.1 4488367 R 440085 CDS YP_002422963.1 218532147 7117493 complement(4489862..4492939) 1 NC_011757.1 TIGRFAM: excinuclease ABC subunit A; PFAM: ABC transporter related; KEGG: mex:Mext_3891 excinuclease ABC subunit A; excinuclease ABC subunit A 4492939 7117493 Mchl_4259 Methylobacterium extorquens CM4 excinuclease ABC subunit A YP_002422963.1 4489862 R 440085 CDS YP_002422964.1 218532148 7117494 4493360..4494418 1 NC_011757.1 KEGG: mex:Mext_3892 methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 4494418 7117494 Mchl_4260 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002422964.1 4493360 D 440085 CDS YP_002422965.1 218532149 7117495 4494581..4496620 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; nitrate and nitrite sensing domain protein; KEGG: mex:Mext_3893 nitrate and nitrite sensing domain-containing protein; methyl-accepting chemotaxis sensory transducer 4496620 7117495 Mchl_4261 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002422965.1 4494581 D 440085 CDS YP_002422966.1 218532150 7117496 complement(4496740..4497945) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3894 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4497945 7117496 Mchl_4262 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422966.1 4496740 R 440085 CDS YP_002422967.1 218532151 7117497 4498100..4501264 1 NC_011757.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_3895 hydrophobe/amphiphile efflux-1 (HAE1) family protein; hydrophobe/amphiphile efflux-1 (HAE1) family transporter 4501264 7117497 Mchl_4263 Methylobacterium extorquens CM4 hydrophobe/amphiphile efflux-1 (HAE1) family transporter YP_002422967.1 4498100 D 440085 CDS YP_002422968.1 218532152 7117498 complement(4501275..4501676) 1 NC_011757.1 KEGG: mex:Mext_3896 hypothetical protein; response regulator receiver protein 4501676 7117498 Mchl_4264 Methylobacterium extorquens CM4 response regulator receiver protein YP_002422968.1 4501275 R 440085 CDS YP_002422969.1 218532153 7117499 complement(4501781..4504573) 1 NC_011757.1 KEGG: mex:Mext_3897 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 4504573 7117499 Mchl_4265 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002422969.1 4501781 R 440085 CDS YP_002422970.1 218532154 7117500 complement(4504799..4505560) 1 NC_011757.1 SMART: regulatory protein Crp; KEGG: mex:Mext_3898 regulatory protein Crp; Crp/Fnr family transcriptional regulator 4505560 7117500 Mchl_4266 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002422970.1 4504799 R 440085 CDS YP_002422971.1 218532155 7117501 complement(4505815..4506666) 1 NC_011757.1 PFAM: glycoside hydrolase family 25; KEGG: mex:Mext_3899 glycoside hydrolase family protein; glycoside hydrolase family protein 4506666 7117501 Mchl_4267 Methylobacterium extorquens CM4 glycoside hydrolase family protein YP_002422971.1 4505815 R 440085 CDS YP_002422972.1 218532156 7117502 4506863..4507315 1 NC_011757.1 PFAM: protein of unknown function DUF1130; KEGG: mex:Mext_3900 hypothetical protein; hypothetical protein 4507315 7117502 Mchl_4268 Methylobacterium extorquens CM4 hypothetical protein YP_002422972.1 4506863 D 440085 CDS YP_002422973.1 218532157 7117503 complement(4507370..4508605) 1 NC_011757.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: mex:Mext_3901 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase; UbiH/UbiF/VisC/COQ6 family Ubiquinone biosynthesis hydroxylase 4508605 7117503 Mchl_4269 Methylobacterium extorquens CM4 UbiH/UbiF/VisC/COQ6 family Ubiquinone biosynthesis hydroxylase YP_002422973.1 4507370 R 440085 CDS YP_002422974.1 218532158 7117504 4509018..4509221 1 NC_011757.1 KEGG: mpo:Mpop_4373 hypothetical protein; hypothetical protein 4509221 7117504 Mchl_4270 Methylobacterium extorquens CM4 hypothetical protein YP_002422974.1 4509018 D 440085 CDS YP_002422975.1 218532159 7117505 4509221..4509445 1 NC_011757.1 KEGG: mex:Mext_3902 hypothetical protein; hypothetical protein 4509445 7117505 Mchl_4271 Methylobacterium extorquens CM4 hypothetical protein YP_002422975.1 4509221 D 440085 CDS YP_002422976.1 218532160 7117506 4509619..4510590 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_3903 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 4510590 7117506 Mchl_4272 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002422976.1 4509619 D 440085 CDS YP_002422977.1 218532161 7117507 4510674..4511300 1 NC_011757.1 PFAM: isochorismatase hydrolase; KEGG: mex:Mext_3904 nicotinamidase; nicotinamidase 4511300 7117507 Mchl_4273 Methylobacterium extorquens CM4 nicotinamidase YP_002422977.1 4510674 D 440085 CDS YP_002422978.1 218532162 7117508 complement(4511470..4512327) 1 NC_011757.1 PFAM: aminotransferase class IV; KEGG: mex:Mext_3905 aminotransferase class IV; class IV aminotransferase 4512327 7117508 Mchl_4274 Methylobacterium extorquens CM4 class IV aminotransferase YP_002422978.1 4511470 R 440085 CDS YP_002422979.1 218532163 7117509 complement(4512314..4512943) 1 NC_011757.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3906 glutamine amidotransferase; glutamine amidotransferase 4512943 7117509 Mchl_4275 Methylobacterium extorquens CM4 glutamine amidotransferase YP_002422979.1 4512314 R 440085 CDS YP_002422980.1 218532164 7117510 complement(4512940..4514340) 1 NC_011757.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: anthranilate synthase component I domain protein; chorismate binding-like; KEGG: mex:Mext_3907 para-aminobenzoate synthase, subunit I; para-aminobenzoate synthase subunit I 4514340 7117510 Mchl_4276 Methylobacterium extorquens CM4 para-aminobenzoate synthase subunit I YP_002422980.1 4512940 R 440085 CDS YP_002422981.1 218532165 7117511 4514793..4516139 1 NC_011757.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 4516139 rimO 7117511 rimO Methylobacterium extorquens CM4 ribosomal protein S12 methylthiotransferase YP_002422981.1 4514793 D 440085 CDS YP_002422982.1 218532166 7117512 4516236..4516421 1 NC_011757.1 KEGG: mex:Mext_3911 hypothetical protein; hypothetical protein 4516421 7117512 Mchl_4278 Methylobacterium extorquens CM4 hypothetical protein YP_002422982.1 4516236 D 440085 CDS YP_002422983.1 218532167 7117513 4516428..4516850 1 NC_011757.1 KEGG: mex:Mext_3912 membrane protein-like protein; hypothetical protein 4516850 7117513 Mchl_4279 Methylobacterium extorquens CM4 hypothetical protein YP_002422983.1 4516428 D 440085 CDS YP_002422984.1 218532168 7117514 4516939..4517130 1 NC_011757.1 KEGG: mpo:Mpop_4385 hypothetical protein; hypothetical protein 4517130 7117514 Mchl_4280 Methylobacterium extorquens CM4 hypothetical protein YP_002422984.1 4516939 D 440085 CDS YP_002422985.1 218532169 7117515 complement(4517216..4518046) 1 NC_011757.1 TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein; MazG family protein 4518046 7117515 Mchl_4281 Methylobacterium extorquens CM4 MazG family protein YP_002422985.1 4517216 R 440085 CDS YP_002422986.1 218532170 7117516 4518812..4519909 1 NC_011757.1 PFAM: plasmid encoded RepA protein; KEGG: mex:Mext_3914 plasmid encoded RepA protein; plasmid encoded RepA protein 4519909 7117516 Mchl_4282 Methylobacterium extorquens CM4 plasmid encoded RepA protein YP_002422986.1 4518812 D 440085 CDS YP_002422987.1 218532171 7117517 4520390..4520944 1 NC_011757.1 KEGG: mex:Mext_3915 hypothetical protein; hypothetical protein 4520944 7117517 Mchl_4283 Methylobacterium extorquens CM4 hypothetical protein YP_002422987.1 4520390 D 440085 CDS YP_002422988.1 218532172 7117518 complement(4521155..4522468) 1 NC_011757.1 PFAM: patatin; KEGG: mex:Mext_3916 patatin; patatin 4522468 7117518 Mchl_4284 Methylobacterium extorquens CM4 patatin YP_002422988.1 4521155 R 440085 CDS YP_002422989.1 218532173 7117519 4522966..4524015 1 NC_011757.1 PFAM: HpcH/HpaI aldolase; KEGG: mex:Mext_3917 HpcH/HpaI aldolase; HpcH/HpaI aldolase 4524015 7117519 Mchl_4285 Methylobacterium extorquens CM4 HpcH/HpaI aldolase YP_002422989.1 4522966 D 440085 CDS YP_002422990.1 218532174 7117520 4524075..4524413 1 NC_011757.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: mex:Mext_3918 hemimethylated DNA binding protein; hemimethylated DNA binding protein 4524413 7117520 Mchl_4286 Methylobacterium extorquens CM4 hemimethylated DNA binding protein YP_002422990.1 4524075 D 440085 CDS YP_002422991.1 218532175 7117521 4524594..4525823 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3919 diguanylate cyclase; diguanylate cyclase 4525823 7117521 Mchl_4287 Methylobacterium extorquens CM4 diguanylate cyclase YP_002422991.1 4524594 D 440085 CDS YP_002422992.1 218532176 7117522 complement(4526000..4526182) 1 NC_011757.1 KEGG: mex:Mext_3920 hypothetical protein; hypothetical protein 4526182 7117522 Mchl_4288 Methylobacterium extorquens CM4 hypothetical protein YP_002422992.1 4526000 R 440085 CDS YP_002422993.1 218532177 7117523 4526465..4527673 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_3921 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4527673 7117523 Mchl_4289 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002422993.1 4526465 D 440085 CDS YP_002422994.1 218532178 7117524 4527684..4530824 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_3922 acriflavin resistance protein; acriflavin resistance protein 4530824 7117524 Mchl_4290 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002422994.1 4527684 D 440085 CDS YP_002422995.1 218532179 7117525 4531240..4532397 1 NC_011757.1 KEGG: mex:Mext_3923 metal dependent phophohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; metal dependent phosphohydrolase 4532397 7117525 Mchl_4291 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002422995.1 4531240 D 440085 CDS YP_002422996.1 218532180 7117526 complement(4532469..4533506) 1 NC_011757.1 TIGRFAM: agmatinase; PFAM: arginase/agmatinase/formiminoglutamase; KEGG: mex:Mext_3924 agmatinase; agmatinase 4533506 7117526 Mchl_4292 Methylobacterium extorquens CM4 agmatinase YP_002422996.1 4532469 R 440085 CDS YP_002422997.1 218532181 7117527 4533859..4534863 1 NC_011757.1 KEGG: mex:Mext_3925 hypothetical protein; hypothetical protein 4534863 7117527 Mchl_4293 Methylobacterium extorquens CM4 hypothetical protein YP_002422997.1 4533859 D 440085 CDS YP_002422998.1 218532182 7117528 complement(4534933..4535247) 1 NC_011757.1 KEGG: mex:Mext_3926 hypothetical protein; hypothetical protein 4535247 7117528 Mchl_4294 Methylobacterium extorquens CM4 hypothetical protein YP_002422998.1 4534933 R 440085 CDS YP_002422999.1 218532183 7117529 complement(4535448..4536740) 1 NC_011757.1 KEGG: mex:Mext_3927 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase 4536740 7117529 Mchl_4295 Methylobacterium extorquens CM4 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase YP_002422999.1 4535448 R 440085 CDS YP_002423000.1 218532184 7117530 complement(4536792..4538357) 1 NC_011757.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: aminoglycoside phosphotransferase; ABC transporter; KEGG: mex:Mext_3928 2-polyprenylphenol 6-hydroxylase; 2-polyprenylphenol 6-hydroxylase 4538357 7117530 Mchl_4296 Methylobacterium extorquens CM4 2-polyprenylphenol 6-hydroxylase YP_002423000.1 4536792 R 440085 CDS YP_002423001.1 218532185 7117531 complement(4538581..4539360) 1 NC_011757.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_3929 ubiquinone/menaquinone biosynthesis methyltransferase; ubiquinone/menaquinone biosynthesis methyltransferase 4539360 7117531 Mchl_4297 Methylobacterium extorquens CM4 ubiquinone/menaquinone biosynthesis methyltransferase YP_002423001.1 4538581 R 440085 CDS YP_002423002.1 218532186 7117532 complement(4539491..4539898) 1 NC_011757.1 KEGG: mex:Mext_3930 dihydrofolate reductase; dihydrofolate reductase 4539898 7117532 Mchl_4298 Methylobacterium extorquens CM4 dihydrofolate reductase YP_002423002.1 4539491 R 440085 CDS YP_002423003.1 218532187 7117533 complement(4539971..4540714) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3931 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4540714 7117533 Mchl_4299 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423003.1 4539971 R 440085 CDS YP_002423004.1 218532188 7117534 complement(4540720..4542195) 1 NC_011757.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 4542195 7117534 Mchl_4300 Methylobacterium extorquens CM4 amidophosphoribosyltransferase YP_002423004.1 4540720 R 440085 CDS YP_002423005.1 218532189 7117535 complement(4542448..4543041) 1 NC_011757.1 PFAM: colicin V production protein; KEGG: mex:Mext_3933 colicin V production protein; colicin V production protein 4543041 7117535 Mchl_4301 Methylobacterium extorquens CM4 colicin V production protein YP_002423005.1 4542448 R 440085 CDS YP_002423006.1 218532190 7118839 4543429..4544547 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_3934 beta-lactamase domain-containing protein; beta-lactamase 4544547 7118839 Mchl_4302 Methylobacterium extorquens CM4 beta-lactamase YP_002423006.1 4543429 D 440085 CDS YP_002423007.1 218532191 7116466 4544540..4545160 1 NC_011757.1 PFAM: electron transporter SCO1/SenC; KEGG: mex:Mext_3935 electron transporter SCO1/SenC; electron transporter SCO1/SenC 4545160 7116466 Mchl_4303 Methylobacterium extorquens CM4 electron transporter SCO1/SenC YP_002423007.1 4544540 D 440085 CDS YP_002423008.1 218532192 7116467 complement(4545167..4546597) 1 NC_011757.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4546597 7116467 Mchl_4304 Methylobacterium extorquens CM4 DNA repair protein RadA YP_002423008.1 4545167 R 440085 CDS YP_002423009.1 218532193 7116468 complement(4546780..4547808) 1 NC_011757.1 KEGG: mex:Mext_3937 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase 4547808 7116468 Mchl_4305 Methylobacterium extorquens CM4 alanine racemase YP_002423009.1 4546780 R 440085 CDS YP_002423010.1 218532194 7116469 complement(4547966..4549453) 1 NC_011757.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase; KEGG: mex:Mext_3938 replicative DNA helicase; replicative DNA helicase 4549453 7116469 Mchl_4306 Methylobacterium extorquens CM4 replicative DNA helicase YP_002423010.1 4547966 R 440085 CDS YP_002423011.1 218532195 7116470 complement(4549774..4550346) 1 NC_011757.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4550346 rplI 7116470 rplI Methylobacterium extorquens CM4 50S ribosomal protein L9 YP_002423011.1 4549774 R 440085 CDS YP_002423012.1 218532196 7116471 complement(4550384..4551442) 1 NC_011757.1 KEGG: mex:Mext_3940 hypothetical protein; hypothetical protein 4551442 7116471 Mchl_4308 Methylobacterium extorquens CM4 hypothetical protein YP_002423012.1 4550384 R 440085 CDS YP_002423013.1 218532197 7116472 complement(4551580..4551834) 1 NC_011757.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4551834 rpsR 7116472 rpsR Methylobacterium extorquens CM4 30S ribosomal protein S18 YP_002423013.1 4551580 R 440085 CDS YP_002423014.1 218532198 7116473 complement(4551837..4552292) 1 NC_011757.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4552292 rpsF 7116473 rpsF Methylobacterium extorquens CM4 30S ribosomal protein S6 YP_002423014.1 4551837 R 440085 CDS YP_002423015.1 218532199 7116474 complement(4552493..4553041) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_3943 gentamicin 3'-N-acetyltransferase; Gentamicin 3'-N-acetyltransferase 4553041 7116474 Mchl_4311 Methylobacterium extorquens CM4 Gentamicin 3'-N-acetyltransferase YP_002423015.1 4552493 R 440085 CDS YP_002423016.1 218532200 7116475 complement(4553051..4553425) 1 NC_011757.1 PFAM: protein of unknown function DUF1696; KEGG: mex:Mext_3944 hypothetical protein; hypothetical protein 4553425 7116475 Mchl_4312 Methylobacterium extorquens CM4 hypothetical protein YP_002423016.1 4553051 R 440085 CDS YP_002423017.1 218532201 7116476 complement(4553497..4553826) 1 NC_011757.1 KEGG: mex:Mext_3945 hypothetical protein; hypothetical protein 4553826 7116476 Mchl_4313 Methylobacterium extorquens CM4 hypothetical protein YP_002423017.1 4553497 R 440085 CDS YP_002423018.1 218532202 7116477 complement(4554236..4554616) 1 NC_011757.1 KEGG: mex:Mext_3946 hypothetical protein; hypothetical protein 4554616 7116477 Mchl_4314 Methylobacterium extorquens CM4 hypothetical protein YP_002423018.1 4554236 R 440085 CDS YP_002423019.1 218532203 7116478 complement(4554862..4555071) 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_3947 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 4555071 7116478 Mchl_4315 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002423019.1 4554862 R 440085 CDS YP_002423020.1 218532204 7116479 complement(4555645..4555905) 1 NC_011757.1 KEGG: mex:Mext_3948 hypothetical protein; hypothetical protein 4555905 7116479 Mchl_4316 Methylobacterium extorquens CM4 hypothetical protein YP_002423020.1 4555645 R 440085 CDS YP_002423021.1 218532205 7116480 4556357..4556887 1 NC_011757.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4556887 7116480 Mchl_4317 Methylobacterium extorquens CM4 peptide deformylase YP_002423021.1 4556357 D 440085 CDS YP_002423022.1 218532206 7116481 4557013..4557456 1 NC_011757.1 KEGG: mex:Mext_3950 hypothetical protein; hypothetical protein 4557456 7116481 Mchl_4318 Methylobacterium extorquens CM4 hypothetical protein YP_002423022.1 4557013 D 440085 CDS YP_002423023.1 218532207 7116482 complement(4557478..4559649) 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_3951 TonB-dependent receptor plug; TonB-dependent receptor plug 4559649 7116482 Mchl_4319 Methylobacterium extorquens CM4 TonB-dependent receptor plug YP_002423023.1 4557478 R 440085 CDS YP_002423024.1 218532208 7116483 4559938..4560783 1 NC_011757.1 KEGG: mex:Mext_3952 hypothetical protein; hypothetical protein 4560783 7116483 Mchl_4320 Methylobacterium extorquens CM4 hypothetical protein YP_002423024.1 4559938 D 440085 CDS YP_002423025.1 218532209 7116484 complement(4560800..4561309) 1 NC_011757.1 KEGG: mex:Mext_3953 hypothetical protein; hypothetical protein 4561309 7116484 Mchl_4321 Methylobacterium extorquens CM4 hypothetical protein YP_002423025.1 4560800 R 440085 CDS YP_002423026.1 218532210 7116485 4561661..4562152 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_3954 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4562152 7116485 Mchl_4322 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002423026.1 4561661 D 440085 CDS YP_002423027.1 218532211 7116486 4562233..4563624 1 NC_011757.1 PFAM: citrate transporter; KEGG: mex:Mext_3955 citrate transporter; citrate transporter 4563624 7116486 Mchl_4323 Methylobacterium extorquens CM4 citrate transporter YP_002423027.1 4562233 D 440085 CDS YP_002423028.1 218532212 7116487 4563785..4565101 1 NC_011757.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4565101 7116487 Mchl_4324 Methylobacterium extorquens CM4 C4-dicarboxylate transporter DctA YP_002423028.1 4563785 D 440085 CDS YP_002423029.1 218532213 7116488 4565218..4566279 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3957 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4566279 7116488 Mchl_4325 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002423029.1 4565218 D 440085 CDS YP_002423030.1 218532214 7116489 complement(4566306..4568012) 1 NC_011757.1 PFAM: fumarate lyase; delta crystallin domain protein; KEGG: mex:Mext_3958 fumarate lyase; fumarate lyase 4568012 7116489 Mchl_4326 Methylobacterium extorquens CM4 fumarate lyase YP_002423030.1 4566306 R 440085 CDS YP_002423031.1 218532215 7116490 complement(4568201..4569742) 1 NC_011757.1 KEGG: mex:Mext_3959 hypothetical protein; hypothetical protein 4569742 7116490 Mchl_4327 Methylobacterium extorquens CM4 hypothetical protein YP_002423031.1 4568201 R 440085 CDS YP_002423032.1 218532216 7116491 4570460..4572124 1 NC_011757.1 PFAM: porin; KEGG: mex:Mext_3960 porin; porin 4572124 7116491 Mchl_4328 Methylobacterium extorquens CM4 porin YP_002423032.1 4570460 D 440085 CDS YP_002423033.1 218532217 7116492 4572327..4573238 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_3961 extracellular solute-binding protein; family 3 extracellular solute-binding protein 4573238 7116492 Mchl_4329 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002423033.1 4572327 D 440085 CDS YP_002423034.1 218532218 7116493 4573273..4573995 1 NC_011757.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3962 polar amino acid ABC transporter inner membrane subunit; polar amino acid ABC transporter inner membrane subunit 4573995 7116493 Mchl_4330 Methylobacterium extorquens CM4 polar amino acid ABC transporter inner membrane subunit YP_002423034.1 4573273 D 440085 CDS YP_002423035.1 218532219 7116494 4573995..4574687 1 NC_011757.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_3963 polar amino acid ABC transporter inner membrane subunit; polar amino acid ABC transporter inner membrane subunit 4574687 7116494 Mchl_4331 Methylobacterium extorquens CM4 polar amino acid ABC transporter inner membrane subunit YP_002423035.1 4573995 D 440085 CDS YP_002423036.1 218532220 7116495 4574714..4575490 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3964 ABC transporter; ABC transporter 4575490 7116495 Mchl_4332 Methylobacterium extorquens CM4 ABC transporter YP_002423036.1 4574714 D 440085 CDS YP_002423037.1 218532221 7116496 complement(4575548..4576489) 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_3965 hypothetical protein; hypothetical protein 4576489 7116496 Mchl_4333 Methylobacterium extorquens CM4 hypothetical protein YP_002423037.1 4575548 R 440085 CDS YP_002423038.1 218532222 7116497 complement(4576525..4577793) 1 NC_011757.1 PFAM: Arsenical pump membrane protein; citrate transporter; KEGG: mex:Mext_3966 arsenical pump membrane protein; Arsenical pump membrane protein 4577793 7116497 Mchl_4334 Methylobacterium extorquens CM4 Arsenical pump membrane protein YP_002423038.1 4576525 R 440085 CDS YP_002423039.1 218532223 7116498 4578170..4578445 1 NC_011757.1 KEGG: mex:Mext_3967 hypothetical protein; hypothetical protein 4578445 7116498 Mchl_4335 Methylobacterium extorquens CM4 hypothetical protein YP_002423039.1 4578170 D 440085 CDS YP_002423040.1 218532224 7116499 complement(4578778..4579395) 1 NC_011757.1 PFAM: propeptide PepSY amd peptidase M4; KEGG: mex:Mext_3968 peptidase; propeptide PepSY amd peptidase M4 4579395 7116499 Mchl_4336 Methylobacterium extorquens CM4 propeptide PepSY amd peptidase M4 YP_002423040.1 4578778 R 440085 CDS YP_002423041.1 218532225 7116500 4579656..4580435 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_3969 NUDIX hydrolase; NUDIX hydrolase 4580435 7116500 Mchl_4337 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002423041.1 4579656 D 440085 CDS YP_002423042.1 218532226 7116501 4580437..4581417 1 NC_011757.1 PFAM: band 7 protein; KEGG: mex:Mext_3970 band 7 protein; band 7 protein 4581417 7116501 Mchl_4338 Methylobacterium extorquens CM4 band 7 protein YP_002423042.1 4580437 D 440085 CDS YP_002423043.1 218532227 7116502 4581429..4582322 1 NC_011757.1 KEGG: mex:Mext_3971 hypothetical protein; hypothetical protein 4582322 7116502 Mchl_4339 Methylobacterium extorquens CM4 hypothetical protein YP_002423043.1 4581429 D 440085 CDS YP_002423044.1 218532228 7116503 4582569..4586651 1 NC_011757.1 TIGRFAM: amino acid adenylation protein; non-ribosomal peptide synthetase; PFAM: AMP-dependent synthetase and ligase; transferase; KEGG: mex:Mext_3972 non-ribosomal peptide synthetase; non-ribosomal peptide synthetase 4586651 7116503 Mchl_4340 Methylobacterium extorquens CM4 non-ribosomal peptide synthetase YP_002423044.1 4582569 D 440085 CDS YP_002423045.1 218532229 7116504 4586730..4586942 1 NC_011757.1 KEGG: cch:Cag_1571 hypothetical protein; hypothetical protein 4586942 7116504 Mchl_4341 Methylobacterium extorquens CM4 hypothetical protein YP_002423045.1 4586730 D 440085 CDS YP_002423046.1 218532230 7116505 4586942..4587220 1 NC_011757.1 PFAM: virulence-associated protein D (VapD) conserved region; KEGG: cch:Cag_1570 virulence-associated protein D; virulence-associated protein D 4587220 7116505 Mchl_4342 Methylobacterium extorquens CM4 virulence-associated protein D YP_002423046.1 4586942 D 440085 CDS YP_002423047.1 218532231 7116506 complement(4587242..4587898) 1 NC_011757.1 KEGG: mex:Mext_3975 hypothetical protein; hypothetical protein 4587898 7116506 Mchl_4343 Methylobacterium extorquens CM4 hypothetical protein YP_002423047.1 4587242 R 440085 CDS YP_002423048.1 218532232 7116507 4588159..4589331 1 NC_011757.1 PFAM: aminotransferase class V; KEGG: mex:Mext_3976 aminotransferase class V; class V aminotransferase 4589331 7116507 Mchl_4344 Methylobacterium extorquens CM4 class V aminotransferase YP_002423048.1 4588159 D 440085 CDS YP_002423049.1 218532233 7116508 4589425..4590894 1 NC_011757.1 TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: mex:Mext_3977 FeS assembly protein SufB; FeS assembly protein SufB 4590894 7116508 Mchl_4345 Methylobacterium extorquens CM4 FeS assembly protein SufB YP_002423049.1 4589425 D 440085 CDS YP_002423050.1 218532234 7116509 4591182..4591934 1 NC_011757.1 KEGG: mex:Mext_3978 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; SMART: ATPase AAA; FeS assembly ATPase SufC 4591934 7116509 Mchl_4346 Methylobacterium extorquens CM4 FeS assembly ATPase SufC YP_002423050.1 4591182 D 440085 CDS YP_002423051.1 218532235 7116510 4591934..4593256 1 NC_011757.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: mex:Mext_3979 FeS assembly protein SufD; FeS assembly protein SufD 4593256 7116510 Mchl_4347 Methylobacterium extorquens CM4 FeS assembly protein SufD YP_002423051.1 4591934 D 440085 CDS YP_002423052.1 218532236 7116511 4593509..4594765 1 NC_011757.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mex:Mext_3980 SufS subfamily cysteine desulfurase; SufS subfamily cysteine desulfurase 4594765 7116511 Mchl_4348 Methylobacterium extorquens CM4 SufS subfamily cysteine desulfurase YP_002423052.1 4593509 D 440085 CDS YP_002423053.1 218532237 7116512 4594816..4595199 1 NC_011757.1 TIGRFAM: FeS assembly SUF system protein; PFAM: protein of unknown function DUF59; KEGG: mex:Mext_3981 FeS assembly SUF system protein; FeS assembly SUF system protein 4595199 7116512 Mchl_4349 Methylobacterium extorquens CM4 FeS assembly SUF system protein YP_002423053.1 4594816 D 440085 CDS YP_002423054.1 218532238 7116513 complement(4595249..4595854) 1 NC_011757.1 PFAM: protein of unknown function DUF820; KEGG: rpe:RPE_4873 protein of unknown function DUF820; hypothetical protein 4595854 7116513 Mchl_4350 Methylobacterium extorquens CM4 hypothetical protein YP_002423054.1 4595249 R 440085 CDS YP_002423055.1 218532239 7116514 4596012..4596392 1 NC_011757.1 TIGRFAM: FeS assembly scaffold SufA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: mex:Mext_3982 FeS assembly scaffold SufA; FeS assembly scaffold SufA 4596392 7116514 Mchl_4351 Methylobacterium extorquens CM4 FeS assembly scaffold SufA YP_002423055.1 4596012 D 440085 CDS YP_002423056.1 218532240 7116515 complement(4596489..4597598) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3983 diguanylate cyclase; diguanylate cyclase 4597598 7116515 Mchl_4352 Methylobacterium extorquens CM4 diguanylate cyclase YP_002423056.1 4596489 R 440085 CDS YP_002423057.1 218532241 7116516 complement(4597793..4599352) 1 NC_011757.1 PFAM: helicase; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: mex:Mext_3984 DEAD/DEAH box helicase domain-containing protein; DEAD/DEAH box helicase 4599352 7116516 Mchl_4353 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002423057.1 4597793 R 440085 CDS YP_002423058.1 218532242 7116517 complement(4599657..4599896) 1 NC_011757.1 KEGG: mex:Mext_3985 hypothetical protein; hypothetical protein 4599896 7116517 Mchl_4354 Methylobacterium extorquens CM4 hypothetical protein YP_002423058.1 4599657 R 440085 CDS YP_002423059.1 218532243 7116518 4600251..4601117 1 NC_011757.1 PFAM: porin; KEGG: mex:Mext_3986 porin; porin 4601117 7116518 Mchl_4355 Methylobacterium extorquens CM4 porin YP_002423059.1 4600251 D 440085 CDS YP_002423060.1 218532244 7116519 4601782..4602186 1 NC_011757.1 KEGG: mex:Mext_3987 hypothetical protein; hypothetical protein 4602186 7116519 Mchl_4356 Methylobacterium extorquens CM4 hypothetical protein YP_002423060.1 4601782 D 440085 CDS YP_002423061.1 218532245 7116520 4602344..4602616 1 NC_011757.1 KEGG: mex:Mext_3988 hypothetical protein; hypothetical protein 4602616 7116520 Mchl_4357 Methylobacterium extorquens CM4 hypothetical protein YP_002423061.1 4602344 D 440085 CDS YP_002423062.1 218532246 7116521 4602679..4603080 1 NC_011757.1 KEGG: mex:Mext_3989 hypothetical protein; hypothetical protein 4603080 7116521 Mchl_4358 Methylobacterium extorquens CM4 hypothetical protein YP_002423062.1 4602679 D 440085 CDS YP_002423063.1 218532247 7116522 4603280..4603570 1 NC_011757.1 KEGG: mex:Mext_3990 hypothetical protein; hypothetical protein 4603570 7116522 Mchl_4359 Methylobacterium extorquens CM4 hypothetical protein YP_002423063.1 4603280 D 440085 CDS YP_002423064.1 218532248 7116523 4603585..4604256 1 NC_011757.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_3991 HAD family hydrolase; HAD-superfamily hydrolase 4604256 7116523 Mchl_4360 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002423064.1 4603585 D 440085 CDS YP_002423065.1 218532249 7116524 4604404..4604601 1 NC_011757.1 KEGG: mex:Mext_3992 hypothetical protein; hypothetical protein 4604601 7116524 Mchl_4361 Methylobacterium extorquens CM4 hypothetical protein YP_002423065.1 4604404 D 440085 CDS YP_002423066.1 218532250 7116525 complement(4604725..4605417) 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_3993 ABC transporter; ABC transporter 4605417 7116525 Mchl_4362 Methylobacterium extorquens CM4 ABC transporter YP_002423066.1 4604725 R 440085 CDS YP_002423067.1 218532251 7116526 4605644..4606294 1 NC_011757.1 PFAM: lipolytic protein G-D-S-L family; KEGG: mex:Mext_3994 GDSL family lipase; G-D-S-L family lipolytic protein 4606294 7116526 Mchl_4363 Methylobacterium extorquens CM4 G-D-S-L family lipolytic protein YP_002423067.1 4605644 D 440085 CDS YP_002423068.1 218532252 7116527 4606301..4606867 1 NC_011757.1 TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: mex:Mext_3995 2'-5' RNA ligase; 2'-5' RNA ligase 4606867 7116527 Mchl_4364 Methylobacterium extorquens CM4 2'-5' RNA ligase YP_002423068.1 4606301 D 440085 CDS YP_002423069.1 218532253 7116529 4607145..4607525 1 NC_011757.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: mex:Mext_3996 preprotein translocase, SecE subunit; preprotein translocase subunit SecE 4607525 7116529 Mchl_4365 Methylobacterium extorquens CM4 preprotein translocase subunit SecE YP_002423069.1 4607145 D 440085 CDS YP_002423070.1 218532254 7116530 4607569..4608102 1 NC_011757.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: KOW domain protein; NGN domain protein; KEGG: mpo:Mpop_4478 NusG antitermination factor; NusG antitermination factor 4608102 7116530 Mchl_4366 Methylobacterium extorquens CM4 NusG antitermination factor YP_002423070.1 4607569 D 440085 CDS YP_002423071.1 218532255 7116531 4608331..4608780 1 NC_011757.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4608780 rplK 7116531 rplK Methylobacterium extorquens CM4 50S ribosomal protein L11 YP_002423071.1 4608331 D 440085 CDS YP_002423072.1 218532256 7116532 4608792..4609490 1 NC_011757.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4609490 rplA 7116532 rplA Methylobacterium extorquens CM4 50S ribosomal protein L1 YP_002423072.1 4608792 D 440085 CDS YP_002423073.1 218532257 7116533 complement(4609817..4611055) 1 NC_011757.1 PFAM: cytochrome P450; KEGG: mex:Mext_4000 cytochrome P450; cytochrome P450 4611055 7116533 Mchl_4369 Methylobacterium extorquens CM4 cytochrome P450 YP_002423073.1 4609817 R 440085 CDS YP_002423074.1 218532258 7116534 complement(4611060..4612322) 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_4001 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4612322 7116534 Mchl_4370 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002423074.1 4611060 R 440085 CDS YP_002423075.1 218532259 7116535 complement(4612319..4612540) 1 NC_011757.1 KEGG: mex:Mext_4002 ferredoxin protein; ferredoxin protein 4612540 7116535 Mchl_4371 Methylobacterium extorquens CM4 ferredoxin protein YP_002423075.1 4612319 R 440085 CDS YP_002423076.1 218532260 7116536 complement(4612695..4613780) 1 NC_011757.1 PFAM: acyltransferase 3; KEGG: mex:Mext_4003 acyltransferase 3; acyltransferase 3 4613780 7116536 Mchl_4372 Methylobacterium extorquens CM4 acyltransferase 3 YP_002423076.1 4612695 R 440085 CDS YP_002423077.1 218532261 7116537 complement(4613777..4614760) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_4004 glycosyl transferase; family 2 glycosyl transferase 4614760 7116537 Mchl_4373 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423077.1 4613777 R 440085 CDS YP_002423078.1 218532262 7116538 complement(4614810..4616624) 1 NC_011757.1 TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain protein; tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mex:Mext_4005 aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 4616624 7116538 Mchl_4374 Methylobacterium extorquens CM4 aspartyl-tRNA synthetase YP_002423078.1 4614810 R 440085 CDS YP_002423079.1 218532263 7116539 complement(4616702..4617709) 1 NC_011757.1 KEGG: mex:Mext_4006 biotin synthase; TIGRFAM: biotin synthase; PFAM: radical SAM protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; biotin synthase 4617709 7116539 Mchl_4375 Methylobacterium extorquens CM4 biotin synthase YP_002423079.1 4616702 R 440085 CDS YP_002423080.1 218532264 7116540 4617903..4618289 1 NC_011757.1 KEGG: mex:Mext_4007 hypothetical protein; hypothetical protein 4618289 7116540 Mchl_4376 Methylobacterium extorquens CM4 hypothetical protein YP_002423080.1 4617903 D 440085 CDS YP_002423081.1 218532265 7116541 complement(4618375..4619259) 1 NC_011757.1 PFAM: fumarylacetoacetate hydrolase; KEGG: mex:Mext_4008 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 4619259 7116541 Mchl_4377 Methylobacterium extorquens CM4 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_002423081.1 4618375 R 440085 CDS YP_002423082.1 218532266 7116542 4619513..4620838 1 NC_011757.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: mex:Mext_4009 membrane protein involved in aromatic hydrocarbon degradation; aromatic hydrocarbon degradation membrane protein 4620838 7116542 Mchl_4378 Methylobacterium extorquens CM4 aromatic hydrocarbon degradation membrane protein YP_002423082.1 4619513 D 440085 CDS YP_002423083.1 218532267 7116543 complement(4620996..4621796) 1 NC_011757.1 PFAM: prephenate dehydrogenase; KEGG: mex:Mext_4010 prephenate dehydrogenase; prephenate dehydrogenase 4621796 7116543 Mchl_4379 Methylobacterium extorquens CM4 prephenate dehydrogenase YP_002423083.1 4620996 R 440085 CDS YP_002423084.1 218532268 7116544 4622174..4624627 1 NC_011757.1 KEGG: mex:Mext_4011 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase 4624627 7116544 Mchl_4380 Methylobacterium extorquens CM4 PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase YP_002423084.1 4622174 D 440085 CDS YP_002423085.1 218532269 7116545 complement(4624728..4626371) 1 NC_011757.1 PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mex:Mext_4012 radical SAM domain-containing protein; radical SAM protein 4626371 7116545 Mchl_4381 Methylobacterium extorquens CM4 radical SAM protein YP_002423085.1 4624728 R 440085 CDS YP_002423086.1 218532270 7116546 4627145..4628653 1 NC_011757.1 PFAM: phosphate-selective porin O and P; KEGG: mex:Mext_4013 phosphate-selective porin O and P; phosphate-selective porin O and P 4628653 7116546 Mchl_4382 Methylobacterium extorquens CM4 phosphate-selective porin O and P YP_002423086.1 4627145 D 440085 CDS YP_002423087.1 218532271 7114777 complement(4628697..4628921) 1 NC_011757.1 KEGG: mpo:Mpop_4496 hypothetical protein; hypothetical protein 4628921 7114777 Mchl_4383 Methylobacterium extorquens CM4 hypothetical protein YP_002423087.1 4628697 R 440085 CDS YP_002423088.1 218532272 7117698 4629521..4630039 1 NC_011757.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4630039 rplJ 7117698 rplJ Methylobacterium extorquens CM4 50S ribosomal protein L10 YP_002423088.1 4629521 D 440085 CDS YP_002423089.1 218532273 7117699 4630097..4630474 1 NC_011757.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4630474 rplL 7117699 rplL Methylobacterium extorquens CM4 50S ribosomal protein L7/L12 YP_002423089.1 4630097 D 440085 CDS YP_002423090.1 218532274 7117700 4630736..4634866 1 NC_011757.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4634866 rpoB 7117700 rpoB Methylobacterium extorquens CM4 DNA-directed RNA polymerase subunit beta YP_002423090.1 4630736 D 440085 CDS YP_002423091.1 218532275 7117701 4635045..4639262 1 NC_011757.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4639262 7117701 Mchl_4387 Methylobacterium extorquens CM4 DNA-directed RNA polymerase subunit beta' YP_002423091.1 4635045 D 440085 CDS YP_002423092.1 218532276 7117702 complement(4639495..4640598) 1 NC_011757.1 PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_4019 extracellular solute-binding protein; family 1 extracellular solute-binding protein 4640598 7117702 Mchl_4388 Methylobacterium extorquens CM4 family 1 extracellular solute-binding protein YP_002423092.1 4639495 R 440085 CDS YP_002423093.1 218532277 7117703 complement(4640595..4640954) 1 NC_011757.1 PFAM: endoribonuclease L-PSP; KEGG: mex:Mext_4020 endoribonuclease L-PSP; endoribonuclease L-PSP 4640954 7117703 Mchl_4389 Methylobacterium extorquens CM4 endoribonuclease L-PSP YP_002423093.1 4640595 R 440085 CDS YP_002423094.1 218532278 7117704 4641205..4641471 1 NC_011757.1 PFAM: transglycosylase; KEGG: mex:Mext_4021 transglycosylase; transglycosylase 4641471 7117704 Mchl_4390 Methylobacterium extorquens CM4 transglycosylase YP_002423094.1 4641205 D 440085 CDS YP_002423095.1 218532279 7117705 complement(4641590..4642483) 1 NC_011757.1 PFAM: NmrA family protein; KEGG: mex:Mext_4022 NmrA family protein; NmrA family protein 4642483 7117705 Mchl_4391 Methylobacterium extorquens CM4 NmrA family protein YP_002423095.1 4641590 R 440085 CDS YP_002423096.1 218532280 7117706 4642561..4643052 1 NC_011757.1 PFAM: helix-turn-helix HxlR type; KEGG: mex:Mext_4023 helix-turn-helix HxlR type; HxlR family transcriptional regulator 4643052 7117706 Mchl_4392 Methylobacterium extorquens CM4 HxlR family transcriptional regulator YP_002423096.1 4642561 D 440085 CDS YP_002423097.1 218532281 7117707 complement(4643109..4643342) 1 NC_011757.1 KEGG: mex:Mext_4024 hypothetical protein; hypothetical protein 4643342 7117707 Mchl_4393 Methylobacterium extorquens CM4 hypothetical protein YP_002423097.1 4643109 R 440085 CDS YP_002423098.1 218532282 7117708 complement(4643424..4644065) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_4025 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 4644065 7117708 Mchl_4394 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002423098.1 4643424 R 440085 CDS YP_002423099.1 218532283 7117709 complement(4644158..4646428) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_4026 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 4646428 7117709 Mchl_4395 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002423099.1 4644158 R 440085 CDS YP_002423100.1 218532284 7117710 complement(4646649..4648886) 1 NC_011757.1 KEGG: mex:Mext_4027 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein; polynucleotide phosphorylase/polyadenylase 4648886 7117710 Mchl_4396 Methylobacterium extorquens CM4 polynucleotide phosphorylase/polyadenylase YP_002423100.1 4646649 R 440085 CDS YP_002423101.1 218532285 7117711 complement(4649156..4649425) 1 NC_011757.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 4649425 rpsO 7117711 rpsO Methylobacterium extorquens CM4 30S ribosomal protein S15 YP_002423101.1 4649156 R 440085 CDS YP_002423102.1 218532286 7117712 4649737..4651203 1 NC_011757.1 PFAM: amino acid permease-associated region; KEGG: mex:Mext_4029 amino acid permease-associated region; amino acid permease-associated protein 4651203 7117712 Mchl_4398 Methylobacterium extorquens CM4 amino acid permease-associated protein YP_002423102.1 4649737 D 440085 CDS YP_002423103.1 218532287 7117713 complement(4651266..4651376) 1 NC_011757.1 KEGG: mpo:Mpop_4511 hypothetical protein; hypothetical protein 4651376 7117713 Mchl_4399 Methylobacterium extorquens CM4 hypothetical protein YP_002423103.1 4651266 R 440085 CDS YP_002423104.1 218532288 7117714 complement(4651446..4652255) 1 NC_011757.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase; KEGG: mex:Mext_4030 exodeoxyribonuclease III Xth; exodeoxyribonuclease III Xth 4652255 7117714 Mchl_4400 Methylobacterium extorquens CM4 exodeoxyribonuclease III Xth YP_002423104.1 4651446 R 440085 CDS YP_002423105.1 218532289 7117715 complement(4652420..4652866) 1 NC_011757.1 PFAM: BLUF domain protein; KEGG: mex:Mext_4031 BLUF domain-containing protein; BLUF domain-containing protein 4652866 7117715 Mchl_4401 Methylobacterium extorquens CM4 BLUF domain-containing protein YP_002423105.1 4652420 R 440085 CDS YP_002423106.1 218532290 7117716 complement(4652883..4654574) 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; hypothetical protein; KEGG: mex:Mext_4032 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 4654574 7117716 Mchl_4402 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002423106.1 4652883 R 440085 CDS YP_002423107.1 218532291 7117717 complement(4654793..4655740) 1 NC_011757.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: mex:Mext_4033 outer membrane lipoprotein carrier protein LolA; outer membrane lipoprotein carrier protein LolA 4655740 7117717 Mchl_4403 Methylobacterium extorquens CM4 outer membrane lipoprotein carrier protein LolA YP_002423107.1 4654793 R 440085 CDS YP_002423108.1 218532292 7117718 complement(4655940..4659215) 1 NC_011757.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: ATPase AAA; KEGG: mex:Mext_4034 cell divisionFtsK/SpoIIIE; cell division FtsK/SpoIIIE 4659215 7117718 Mchl_4404 Methylobacterium extorquens CM4 cell division FtsK/SpoIIIE YP_002423108.1 4655940 R 440085 CDS YP_002423109.1 218532293 7117719 4659653..4661725 1 NC_011757.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 4661725 nadE 7117719 nadE Methylobacterium extorquens CM4 NAD synthetase YP_002423109.1 4659653 D 440085 CDS YP_002423110.1 218532294 7117720 complement(4661742..4662206) 1 NC_011757.1 LovR from Caulobacter crescentus is a response regulator part of a two-component signaling system that regulates photosensitive bacterial cell-surface and cell-cell attachment; response regulator 4662206 7117720 Mchl_4406 Methylobacterium extorquens CM4 response regulator YP_002423110.1 4661742 R 440085 CDS YP_002423111.1 218532295 7117721 complement(4662340..4663440) 1 NC_011757.1 KEGG: mex:Mext_4037 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 4663440 7117721 Mchl_4407 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002423111.1 4662340 R 440085 CDS YP_002423112.1 218532296 7117722 4663832..4665280 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4038 major facilitator transporter; major facilitator superfamily protein 4665280 7117722 Mchl_4408 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423112.1 4663832 D 440085 CDS YP_002423113.1 218532297 7117723 4665277..4666203 1 NC_011757.1 KEGG: mex:Mext_4039 hypothetical protein; hypothetical protein 4666203 7117723 Mchl_4409 Methylobacterium extorquens CM4 hypothetical protein YP_002423113.1 4665277 D 440085 CDS YP_002423114.1 218532298 7117724 complement(4666387..4667571) 1 NC_011757.1 KEGG: mex:Mext_4040 hypothetical protein; hypothetical protein 4667571 7117724 Mchl_4410 Methylobacterium extorquens CM4 hypothetical protein YP_002423114.1 4666387 R 440085 CDS YP_002423115.1 218532299 7117725 4667652..4668257 1 NC_011757.1 PFAM: NnrUfamily protein; KEGG: mex:Mext_4041 NnrU family protein; NnrU family protein 4668257 7117725 Mchl_4411 Methylobacterium extorquens CM4 NnrU family protein YP_002423115.1 4667652 D 440085 CDS YP_002423116.1 218532300 7117726 4668650..4669360 1 NC_011757.1 KEGG: mex:Mext_4042 hypothetical protein; hypothetical protein 4669360 7117726 Mchl_4412 Methylobacterium extorquens CM4 hypothetical protein YP_002423116.1 4668650 D 440085 CDS YP_002423117.1 218532301 7117727 4669447..4670787 1 NC_011757.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 4670787 engA 7117727 engA Methylobacterium extorquens CM4 GTP-binding protein EngA YP_002423117.1 4669447 D 440085 CDS YP_002423118.1 218532302 7117728 4670955..4671857 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_4044 hypothetical protein; hypothetical protein 4671857 7117728 Mchl_4414 Methylobacterium extorquens CM4 hypothetical protein YP_002423118.1 4670955 D 440085 CDS YP_002423119.1 218532303 7117729 complement(4671861..4672985) 1 NC_011757.1 PFAM: glutamate--cysteine ligase; KEGG: mex:Mext_4045 glutamate--cysteine ligase; glutamate--cysteine ligase 4672985 7117729 Mchl_4415 Methylobacterium extorquens CM4 glutamate--cysteine ligase YP_002423119.1 4671861 R 440085 CDS YP_002423120.1 218532304 7117730 4673226..4674125 1 NC_011757.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4674125 7117730 Mchl_4416 Methylobacterium extorquens CM4 formamidopyrimidine-DNA glycosylase YP_002423120.1 4673226 D 440085 CDS YP_002423121.1 218532305 7117731 4674346..4674549 1 NC_011757.1 KEGG: mex:Mext_4047 hypothetical protein; hypothetical protein 4674549 7117731 Mchl_4417 Methylobacterium extorquens CM4 hypothetical protein YP_002423121.1 4674346 D 440085 CDS YP_002423122.1 218532306 7117732 4674692..4675156 1 NC_011757.1 PFAM: protein of unknown function UPF0074; KEGG: mex:Mext_4048 hypothetical protein; BadM/Rrf2 family transcriptional regulator 4675156 7117732 Mchl_4418 Methylobacterium extorquens CM4 BadM/Rrf2 family transcriptional regulator YP_002423122.1 4674692 D 440085 CDS YP_002423123.1 218532307 7117733 4675146..4676054 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mex:Mext_4049 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4676054 7117733 Mchl_4419 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002423123.1 4675146 D 440085 CDS YP_002423124.1 218532308 7117734 4676349..4677908 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_4050 beta-lactamase; beta-lactamase 4677908 7117734 Mchl_4420 Methylobacterium extorquens CM4 beta-lactamase YP_002423124.1 4676349 D 440085 CDS YP_002423125.1 218532309 7117735 complement(4678000..4680351) 1 NC_011757.1 KEGG: mex:Mext_4051 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 4680351 7117735 Mchl_4421 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002423125.1 4678000 R 440085 CDS YP_002423126.1 218532310 7117736 complement(4680457..4681185) 1 NC_011757.1 KEGG: mex:Mext_4052 glutathione S-transferase-like protein; glutathione S-transferase-like protein 4681185 7117736 Mchl_4422 Methylobacterium extorquens CM4 glutathione S-transferase-like protein YP_002423126.1 4680457 R 440085 CDS YP_002423127.1 218532311 7117737 complement(4681205..4681882) 1 NC_011757.1 PFAM: protein of unknown function DUF937; KEGG: mex:Mext_4053 hypothetical protein; hypothetical protein 4681882 7117737 Mchl_4423 Methylobacterium extorquens CM4 hypothetical protein YP_002423127.1 4681205 R 440085 CDS YP_002423128.1 218532312 7117738 complement(4681972..4682268) 1 NC_011757.1 KEGG: mex:Mext_4054 hypothetical protein; hypothetical protein 4682268 7117738 Mchl_4424 Methylobacterium extorquens CM4 hypothetical protein YP_002423128.1 4681972 R 440085 CDS YP_002423129.1 218532313 7117739 complement(4682386..4685136) 1 NC_011757.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 4685136 7117739 Mchl_4425 Methylobacterium extorquens CM4 excinuclease ABC subunit B YP_002423129.1 4682386 R 440085 CDS YP_002423130.1 218532314 7117740 complement(4685346..4686254) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mpo:Mpop_4540 LysR family transcriptional regulator; LysR family transcriptional regulator 4686254 7117740 Mchl_4426 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423130.1 4685346 R 440085 CDS YP_002423131.1 218532315 7117741 4686376..4686771 1 NC_011757.1 PFAM: DoxX family protein; KEGG: mex:Mext_4059 DoxX family protein; DoxX family protein 4686771 7117741 Mchl_4427 Methylobacterium extorquens CM4 DoxX family protein YP_002423131.1 4686376 D 440085 CDS YP_002423132.1 218532316 7117742 4686797..4687279 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_4060 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 4687279 7117742 Mchl_4428 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002423132.1 4686797 D 440085 CDS YP_002423133.1 218532317 7117743 4687358..4688035 1 NC_011757.1 KEGG: mex:Mext_4061 hypothetical protein; hypothetical protein 4688035 7117743 Mchl_4429 Methylobacterium extorquens CM4 hypothetical protein YP_002423133.1 4687358 D 440085 CDS YP_002423134.1 218532318 7117744 4688022..4688465 1 NC_011757.1 KEGG: mex:Mext_4062 hypothetical protein; hypothetical protein 4688465 7117744 Mchl_4430 Methylobacterium extorquens CM4 hypothetical protein YP_002423134.1 4688022 D 440085 CDS YP_002423135.1 218532319 7117745 4688537..4689247 1 NC_011757.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 4689247 7117745 Mchl_4431 Methylobacterium extorquens CM4 undecaprenyl pyrophosphate synthase YP_002423135.1 4688537 D 440085 CDS YP_002423136.1 218532320 7117746 4689274..4689861 1 NC_011757.1 PFAM: ankyrin; KEGG: mex:Mext_4065 ankyrin; ankyrin 4689861 7117746 Mchl_4432 Methylobacterium extorquens CM4 ankyrin YP_002423136.1 4689274 D 440085 CDS YP_002423137.1 218532321 7117747 4689949..4691454 1 NC_011757.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: mex:Mext_4066 glycerol kinase; glycerol kinase 4691454 7117747 Mchl_4433 Methylobacterium extorquens CM4 glycerol kinase YP_002423137.1 4689949 D 440085 CDS YP_002423138.1 218532322 7117748 4691454..4692617 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_4067 hypothetical protein; hypothetical protein 4692617 7117748 Mchl_4434 Methylobacterium extorquens CM4 hypothetical protein YP_002423138.1 4691454 D 440085 CDS YP_002423139.1 218532323 7117749 4692823..4694508 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_4068 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 4694508 7117749 Mchl_4435 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423139.1 4692823 D 440085 CDS YP_002423140.1 218532324 7117750 complement(4694562..4695323) 1 NC_011757.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: mex:Mext_4069 glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 4695323 7117750 Mchl_4436 Methylobacterium extorquens CM4 glycerophosphoryl diester phosphodiesterase YP_002423140.1 4694562 R 440085 CDS YP_002423141.1 218532325 7117751 complement(4695320..4695793) 1 NC_011757.1 PFAM: endoribonuclease L-PSP; KEGG: mex:Mext_4070 endoribonuclease L-PSP; endoribonuclease L-PSP 4695793 7117751 Mchl_4437 Methylobacterium extorquens CM4 endoribonuclease L-PSP YP_002423141.1 4695320 R 440085 CDS YP_002423142.1 218532326 7117752 complement(4695873..4698044) 1 NC_011757.1 PFAM: ABC transporter transmembrane region; ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase; KEGG: mex:Mext_4071 ABC transporter; ABC transporter 4698044 7117752 Mchl_4438 Methylobacterium extorquens CM4 ABC transporter YP_002423142.1 4695873 R 440085 CDS YP_002423143.1 218532327 7117753 complement(4698041..4699330) 1 NC_011757.1 KEGG: mex:Mext_4072 secretion protein HlyD family protein; secretion protein HlyD 4699330 7117753 Mchl_4439 Methylobacterium extorquens CM4 secretion protein HlyD YP_002423143.1 4698041 R 440085 CDS YP_002423144.1 218532328 7117754 4699807..4700019 1 NC_011757.1 KEGG: mpo:Mpop_4554 hypothetical protein; hypothetical protein 4700019 7117754 Mchl_4440 Methylobacterium extorquens CM4 hypothetical protein YP_002423144.1 4699807 D 440085 CDS YP_002423145.1 218532329 7117755 4700365..4701267 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_4074 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 4701267 7117755 Mchl_4441 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002423145.1 4700365 D 440085 CDS YP_002423146.1 218532330 7117756 4701481..4702671 1 NC_011757.1 TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: mex:Mext_4075 acetylornithine and succinylornithine aminotransferase; acetylornithine and succinylornithine aminotransferase 4702671 7117756 Mchl_4442 Methylobacterium extorquens CM4 acetylornithine and succinylornithine aminotransferase YP_002423146.1 4701481 D 440085 CDS YP_002423147.1 218532331 7117757 4702700..4703650 1 NC_011757.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: mex:Mext_4076 ornithine carbamoyltransferase; ornithine carbamoyltransferase 4703650 7117757 Mchl_4443 Methylobacterium extorquens CM4 ornithine carbamoyltransferase YP_002423147.1 4702700 D 440085 CDS YP_002423148.1 218532332 7117758 complement(4703709..4703948) 1 NC_011757.1 KEGG: mex:Mext_1752 hypothetical protein; hypothetical protein 4703948 7117758 Mchl_4444 Methylobacterium extorquens CM4 hypothetical protein YP_002423148.1 4703709 R 440085 CDS YP_002423149.1 218532333 7117759 complement(4704107..4704574) 1 NC_011757.1 PFAM: activator of Hsp90 ATPase 1 family protein; KEGG: mex:Mext_4077 activator of HSP90 ATPase 1 family protein; activator of Hsp90 ATPase 1 family protein 4704574 7117759 Mchl_4445 Methylobacterium extorquens CM4 activator of Hsp90 ATPase 1 family protein YP_002423149.1 4704107 R 440085 CDS YP_002423150.1 218532334 7117760 complement(4704594..4705016) 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: mex:Mext_4078 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 4705016 7117760 Mchl_4446 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002423150.1 4704594 R 440085 CDS YP_002423151.1 218532335 7117761 4705302..4706108 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4079 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4706108 7117761 Mchl_4447 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423151.1 4705302 D 440085 CDS YP_002423152.1 218532336 7117762 4706112..4707494 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mex:Mext_4080 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4707494 7117762 Mchl_4448 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002423152.1 4706112 D 440085 CDS YP_002423153.1 218532337 7117763 4707718..4710345 1 NC_011757.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; Phytochrome central region domain protein; PAS fold-2 domain protein; PAS fold domain protein; KEGG: mex:Mext_4081 histidine kinase dimerisation/phosphoacceptor; multi-sensor signal transduction histidine kinase 4710345 7117763 Mchl_4449 Methylobacterium extorquens CM4 multi-sensor signal transduction histidine kinase YP_002423153.1 4707718 D 440085 CDS YP_002423154.1 218532338 7117764 4710353..4710910 1 NC_011757.1 PFAM: Haem oxygenase-like; KEGG: mex:Mext_4082 heme oxygenase; heme oxygenase-like protein 4710910 7117764 Mchl_4450 Methylobacterium extorquens CM4 heme oxygenase-like protein YP_002423154.1 4710353 D 440085 CDS YP_002423155.1 218532339 7117765 complement(4710973..4712136) 1 NC_011757.1 KEGG: mex:Mext_4083 hypothetical protein; hypothetical protein 4712136 7117765 Mchl_4451 Methylobacterium extorquens CM4 hypothetical protein YP_002423155.1 4710973 R 440085 CDS YP_002423156.1 218532340 7117766 complement(4712129..4712623) 1 NC_011757.1 KEGG: mex:Mext_4084 hypothetical protein; hypothetical protein 4712623 7117766 Mchl_4452 Methylobacterium extorquens CM4 hypothetical protein YP_002423156.1 4712129 R 440085 CDS YP_002423157.1 218532341 7117767 4712879..4714225 1 NC_011757.1 KEGG: mex:Mext_4085 capsule polysaccharide export protein-like protein; capsule polysaccharide export protein-like protein 4714225 7117767 Mchl_4453 Methylobacterium extorquens CM4 capsule polysaccharide export protein-like protein YP_002423157.1 4712879 D 440085 CDS YP_002423158.1 218532342 7117768 4714380..4714664 1 NC_011757.1 KEGG: mex:Mext_4086 hypothetical protein; hypothetical protein 4714664 7117768 Mchl_4454 Methylobacterium extorquens CM4 hypothetical protein YP_002423158.1 4714380 D 440085 CDS YP_002423159.1 218532343 7117769 4714856..4715836 1 NC_011757.1 KEGG: mex:Mext_4087 hypothetical protein; hypothetical protein 4715836 7117769 Mchl_4455 Methylobacterium extorquens CM4 hypothetical protein YP_002423159.1 4714856 D 440085 CDS YP_002423160.1 218532344 7117770 complement(4715869..4717242) 1 NC_011757.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_4088 sigma-54 factor interaction domain-containing protein; Fis family transcriptional regulator 4717242 7117770 Mchl_4456 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002423160.1 4715869 R 440085 CDS YP_002423161.1 218532345 7117771 complement(4717396..4717743) 1 NC_011757.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: mex:Mext_4089 flagellar motor switch protein FliN; flagellar motor switch protein FliN 4717743 7117771 Mchl_4457 Methylobacterium extorquens CM4 flagellar motor switch protein FliN YP_002423161.1 4717396 R 440085 CDS YP_002423162.1 218532346 7117772 complement(4717749..4718375) 1 NC_011757.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 4718375 fliH 7117772 fliH Methylobacterium extorquens CM4 flagellar assembly protein H YP_002423162.1 4717749 R 440085 CDS YP_002423163.1 218532347 7117773 complement(4718372..4719427) 1 NC_011757.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 4719427 fliG 7117773 fliG Methylobacterium extorquens CM4 flagellar motor switch protein G YP_002423163.1 4718372 R 440085 CDS YP_002423164.1 218532348 7117774 complement(4719471..4721093) 1 NC_011757.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 4721093 fliF 7117774 fliF Methylobacterium extorquens CM4 flagellar MS-ring protein YP_002423164.1 4719471 R 440085 CDS YP_002423165.1 218532349 7117775 complement(4721354..4721629) 1 NC_011757.1 PFAM: protein of unknown function DUF1153; KEGG: mex:Mext_4093 hypothetical protein; hypothetical protein 4721629 7117775 Mchl_4461 Methylobacterium extorquens CM4 hypothetical protein YP_002423165.1 4721354 R 440085 CDS YP_002423166.1 218532350 7117776 complement(4721771..4722451) 1 NC_011757.1 PFAM: flagellar hook capping protein; KEGG: mex:Mext_4094 flagellar hook capping protein; flagellar hook capping protein 4722451 7117776 Mchl_4462 Methylobacterium extorquens CM4 flagellar hook capping protein YP_002423166.1 4721771 R 440085 CDS YP_002423167.1 218532351 7117777 complement(4722461..4723852) 1 NC_011757.1 PFAM: flagellar hook-length control protein; KEGG: mex:Mext_4095 flagellar hook-length control protein; flagellar hook-length control protein 4723852 7117777 Mchl_4463 Methylobacterium extorquens CM4 flagellar hook-length control protein YP_002423167.1 4722461 R 440085 CDS YP_002423168.1 218532352 7117778 4724111..4725343 1 NC_011757.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 4725343 mnmA 7117778 mnmA Methylobacterium extorquens CM4 tRNA-specific 2-thiouridylase MnmA YP_002423168.1 4724111 D 440085 CDS YP_002423169.1 218532353 7118145 4725599..4726255 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_4097 phosphatidylethanolamine N-methyltransferase; phosphatidylethanolamine N-methyltransferase 4726255 7118145 Mchl_4465 Methylobacterium extorquens CM4 phosphatidylethanolamine N-methyltransferase YP_002423169.1 4725599 D 440085 CDS YP_002423170.1 218532354 7118431 4726294..4727142 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_4098 hypothetical protein; hypothetical protein 4727142 7118431 Mchl_4466 Methylobacterium extorquens CM4 hypothetical protein YP_002423170.1 4726294 D 440085 CDS YP_002423171.1 218532355 7118432 4727316..4728800 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: mex:Mext_4099 ATPase domain-containing protein; histidine kinase 4728800 7118432 Mchl_4467 Methylobacterium extorquens CM4 histidine kinase YP_002423171.1 4727316 D 440085 CDS YP_002423172.1 218532356 7118433 complement(4728865..4729605) 1 NC_011757.1 PFAM: carbonic anhydrase; KEGG: mex:Mext_4100 carbonic anhydrase; carbonic anhydrase 4729605 7118433 Mchl_4468 Methylobacterium extorquens CM4 carbonic anhydrase YP_002423172.1 4728865 R 440085 CDS YP_002423173.1 218532357 7118434 complement(4729914..4731491) 1 NC_011757.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4101 EmrB/QacA family drug resistance transporter; EmrB/QacA subfamily drug resistance transporter 4731491 7118434 Mchl_4469 Methylobacterium extorquens CM4 EmrB/QacA subfamily drug resistance transporter YP_002423173.1 4729914 R 440085 CDS YP_002423174.1 218532358 7118435 complement(4731703..4732908) 1 NC_011757.1 PFAM: secretion protein HlyD; KEGG: mex:Mext_4102 secretion protein HlyD; secretion protein HlyD 4732908 7118435 Mchl_4470 Methylobacterium extorquens CM4 secretion protein HlyD YP_002423174.1 4731703 R 440085 CDS YP_002423175.1 218532359 7118436 4733049..4733711 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_4103 regulatory protein TetR; TetR family transcriptional regulator 4733711 7118436 Mchl_4471 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002423175.1 4733049 D 440085 CDS YP_002423176.1 218532360 7118437 complement(4733718..4735481) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_4104 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 4735481 7118437 Mchl_4472 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002423176.1 4733718 R 440085 CDS YP_002423177.1 218532361 7118438 4735591..4736580 1 NC_011757.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC domain; KEGG: mex:Mext_4105 SUA5/YciO/YrdC/YwlC family protein; Sua5/YciO/YrdC/YwlC family protein 4736580 7118438 Mchl_4473 Methylobacterium extorquens CM4 Sua5/YciO/YrdC/YwlC family protein YP_002423177.1 4735591 D 440085 CDS YP_002423178.1 218532362 7118439 complement(4736624..4737220) 1 NC_011757.1 KEGG: mex:Mext_4106 hypothetical protein; hypothetical protein 4737220 7118439 Mchl_4474 Methylobacterium extorquens CM4 hypothetical protein YP_002423178.1 4736624 R 440085 CDS YP_002423179.1 218532363 7118440 complement(4737488..4739251) 1 NC_011757.1 KEGG: mex:Mext_4107 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 4739251 7118440 Mchl_4475 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002423179.1 4737488 R 440085 CDS YP_002423180.1 218532364 7118441 complement(4739241..4739576) 1 NC_011757.1 PFAM: KaiB domain protein; KEGG: mex:Mext_4108 KaiB domain-containing protein; KaiB domain-containing protein 4739576 7118441 Mchl_4476 Methylobacterium extorquens CM4 KaiB domain-containing protein YP_002423180.1 4739241 R 440085 CDS YP_002423181.1 218532365 7118442 complement(4739573..4739965) 1 NC_011757.1 PFAM: KaiB domain protein; KEGG: mex:Mext_4109 KaiB domain-containing protein; KaiB domain-containing protein 4739965 7118442 Mchl_4477 Methylobacterium extorquens CM4 KaiB domain-containing protein YP_002423181.1 4739573 R 440085 CDS YP_002423182.1 218532366 7118443 complement(4739962..4741689) 1 NC_011757.1 acts as a promotor non-specific transcription repressor; circadian clock protein KaiC 4741689 7118443 Mchl_4478 Methylobacterium extorquens CM4 circadian clock protein KaiC YP_002423182.1 4739962 R 440085 CDS YP_002423183.1 218532367 7118444 complement(4741679..4741909) 1 NC_011757.1 KEGG: mex:Mext_4111 hypothetical protein; hypothetical protein 4741909 7118444 Mchl_4479 Methylobacterium extorquens CM4 hypothetical protein YP_002423183.1 4741679 R 440085 CDS YP_002423184.1 218532368 7118445 4742106..4742492 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4112 response regulator receiver; response regulator receiver protein 4742492 7118445 Mchl_4480 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423184.1 4742106 D 440085 CDS YP_002423185.1 218532369 7118446 complement(4742515..4743861) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; KEGG: mex:Mext_4113 ATPase domain-containing protein; histidine kinase 4743861 7118446 Mchl_4481 Methylobacterium extorquens CM4 histidine kinase YP_002423185.1 4742515 R 440085 CDS YP_002423186.1 218532370 7118447 complement(4743858..4744523) 1 NC_011757.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_4114 response regulator receiver; transcriptional regulator 4744523 7118447 Mchl_4482 Methylobacterium extorquens CM4 transcriptional regulator YP_002423186.1 4743858 R 440085 CDS YP_002423187.1 218532371 7118448 complement(4744548..4744880) 1 NC_011757.1 KEGG: mex:Mext_4115 hypothetical protein; hypothetical protein 4744880 7118448 Mchl_4483 Methylobacterium extorquens CM4 hypothetical protein YP_002423187.1 4744548 R 440085 CDS YP_002423188.1 218532372 7118449 4745047..4745682 1 NC_011757.1 SMART: nuclease (SNase domain protein); KEGG: mex:Mext_4116 nuclease; nuclease 4745682 7118449 Mchl_4484 Methylobacterium extorquens CM4 nuclease YP_002423188.1 4745047 D 440085 CDS YP_002423189.1 218532373 7118450 complement(4745698..4745991) 1 NC_011757.1 KEGG: mex:Mext_4117 hypothetical protein; hypothetical protein 4745991 7118450 Mchl_4485 Methylobacterium extorquens CM4 hypothetical protein YP_002423189.1 4745698 R 440085 CDS YP_002423190.1 218532374 7118451 complement(4745991..4746341) 1 NC_011757.1 KEGG: mex:Mext_4118 iron uptake protein; iron uptake protein 4746341 7118451 Mchl_4486 Methylobacterium extorquens CM4 iron uptake protein YP_002423190.1 4745991 R 440085 CDS YP_002423191.1 218532375 7118452 complement(4746338..4747930) 1 NC_011757.1 KEGG: mex:Mext_4119 PepSY-associated TM helix domain-containing protein; PepSY-associated TM helix domain-containing protein 4747930 7118452 Mchl_4487 Methylobacterium extorquens CM4 PepSY-associated TM helix domain-containing protein YP_002423191.1 4746338 R 440085 CDS YP_002423192.1 218532376 7118453 complement(4747927..4748241) 1 NC_011757.1 KEGG: mex:Mext_4120 iron uptake protein; iron uptake protein 4748241 7118453 Mchl_4488 Methylobacterium extorquens CM4 iron uptake protein YP_002423192.1 4747927 R 440085 CDS YP_002423193.1 218532377 7118454 complement(4748251..4750608) 1 NC_011757.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mex:Mext_4121 TonB-dependent siderophore receptor; TonB-dependent siderophore receptor 4750608 7118454 Mchl_4489 Methylobacterium extorquens CM4 TonB-dependent siderophore receptor YP_002423193.1 4748251 R 440085 CDS YP_002423194.1 218532378 7118455 complement(4750850..4751128) 1 NC_011757.1 KEGG: mex:Mext_4122 hypothetical protein; hypothetical protein 4751128 7118455 Mchl_4490 Methylobacterium extorquens CM4 hypothetical protein YP_002423194.1 4750850 R 440085 CDS YP_002423195.1 218532379 7118456 4751775..4751966 1 NC_011757.1 KEGG: mpo:Mpop_4605 hypothetical protein; hypothetical protein 4751966 7118456 Mchl_4491 Methylobacterium extorquens CM4 hypothetical protein YP_002423195.1 4751775 D 440085 CDS YP_002423196.1 218532380 7118457 4752482..4758043 1 NC_011757.1 KEGG: mex:Mext_4124 hypothetical protein; hypothetical protein 4758043 7118457 Mchl_4492 Methylobacterium extorquens CM4 hypothetical protein YP_002423196.1 4752482 D 440085 CDS YP_002423197.1 218532381 7118458 4758121..4759644 1 NC_011757.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: mex:Mext_4125 phosphoglucomutase/phosphomannomutase alpha/beta/subunit; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 4759644 7118458 Mchl_4493 Methylobacterium extorquens CM4 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_002423197.1 4758121 D 440085 CDS YP_002423198.1 218532382 7118459 4760054..4761547 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_4126 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 4761547 7118459 Mchl_4494 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002423198.1 4760054 D 440085 CDS YP_002423199.1 218532383 7118460 4761924..4763351 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_4127 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 4763351 7118460 Mchl_4495 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002423199.1 4761924 D 440085 CDS YP_002423200.1 218532384 7118461 complement(4763505..4763762) 1 NC_011757.1 KEGG: mex:Mext_4128 hypothetical protein; hypothetical protein 4763762 7118461 Mchl_4496 Methylobacterium extorquens CM4 hypothetical protein YP_002423200.1 4763505 R 440085 CDS YP_002423201.1 218532385 7118462 complement(4763762..4765966) 1 NC_011757.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: mex:Mext_4129 lipopolysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 4765966 7118462 Mchl_4497 Methylobacterium extorquens CM4 lipopolysaccharide biosynthesis protein YP_002423201.1 4763762 R 440085 CDS YP_002423202.1 218532386 7118463 complement(4766037..4767560) 1 NC_011757.1 KEGG: mex:Mext_4130 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 4767560 7118463 Mchl_4498 Methylobacterium extorquens CM4 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_002423202.1 4766037 R 440085 CDS YP_002423203.1 218532387 7118464 complement(4767621..4768622) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: mex:Mext_4131 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4768622 7118464 Mchl_4499 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002423203.1 4767621 R 440085 CDS YP_002423204.1 218532388 7118465 complement(4769001..4769780) 1 NC_011757.1 KEGG: mex:Mext_4132 WecB/TagA/CpsF family glycosyl transferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; WecB/TagA/CpsF family glycosyl transferase 4769780 7118465 Mchl_4500 Methylobacterium extorquens CM4 WecB/TagA/CpsF family glycosyl transferase YP_002423204.1 4769001 R 440085 CDS YP_002423205.1 218532389 7118466 complement(4769777..4770778) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_4133 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 4770778 7118466 Mchl_4501 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002423205.1 4769777 R 440085 CDS YP_002423206.1 218532390 7118467 4771235..4772602 1 NC_011757.1 PFAM: polysaccharide export protein; KEGG: mex:Mext_4134 polysaccharide export protein; polysaccharide export protein 4772602 7118467 Mchl_4502 Methylobacterium extorquens CM4 polysaccharide export protein YP_002423206.1 4771235 D 440085 CDS YP_002423207.1 218532391 7118468 4772655..4774064 1 NC_011757.1 KEGG: mex:Mext_4135 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4774064 7118468 Mchl_4503 Methylobacterium extorquens CM4 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002423207.1 4772655 D 440085 CDS YP_002423208.1 218532392 7118469 4774074..4774463 1 NC_011757.1 KEGG: mex:Mext_4136 hypothetical protein; hypothetical protein 4774463 7118469 Mchl_4504 Methylobacterium extorquens CM4 hypothetical protein YP_002423208.1 4774074 D 440085 CDS YP_002423209.1 218532393 7118470 complement(4774647..4775324) 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_4137 response regulator receiver; LuxR family transcriptional regulator 4775324 7118470 Mchl_4505 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423209.1 4774647 R 440085 CDS YP_002423210.1 218532394 7118471 complement(4775321..4775908) 1 NC_011757.1 KEGG: mex:Mext_4138 hypothetical protein; hypothetical protein 4775908 7118471 Mchl_4506 Methylobacterium extorquens CM4 hypothetical protein YP_002423210.1 4775321 R 440085 CDS YP_002423211.1 218532395 7118472 complement(4775905..4776849) 1 NC_011757.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: mex:Mext_4139 YVTN beta-propeller repeat-containing protein; 40-residue YVTN family beta-propeller repeat-containing protein 4776849 7118472 Mchl_4507 Methylobacterium extorquens CM4 40-residue YVTN family beta-propeller repeat-containing protein YP_002423211.1 4775905 R 440085 CDS YP_002423212.1 218532396 7118473 complement(4776874..4777404) 1 NC_011757.1 KEGG: mex:Mext_4140 MxaD protein; MxaD protein 4777404 7118473 Mchl_4508 Methylobacterium extorquens CM4 MxaD protein YP_002423212.1 4776874 R 440085 CDS YP_002423213.1 218532397 7118474 complement(4777404..4778399) 1 NC_011757.1 SMART: von Willebrand factor type A; KEGG: mex:Mext_4141 von Willebrand factor type A; von Willebrand factor type A 4778399 7118474 Mchl_4509 Methylobacterium extorquens CM4 von Willebrand factor type A YP_002423213.1 4777404 R 440085 CDS YP_002423214.1 218532398 7118475 complement(4778396..4779022) 1 NC_011757.1 KEGG: mex:Mext_4142 hypothetical protein; hypothetical protein 4779022 7118475 Mchl_4510 Methylobacterium extorquens CM4 hypothetical protein YP_002423214.1 4778396 R 440085 CDS YP_002423215.1 218532399 7118476 complement(4779022..4780089) 1 NC_011757.1 SMART: von Willebrand factor type A; KEGG: mex:Mext_4143 von Willebrand factor type A; von Willebrand factor type A 4780089 7118476 Mchl_4511 Methylobacterium extorquens CM4 von Willebrand factor type A YP_002423215.1 4779022 R 440085 CDS YP_002423216.1 218532400 7118477 complement(4780094..4781017) 1 NC_011757.1 KEGG: mex:Mext_4144 MxaA protein; MxaA protein 4781017 7118477 Mchl_4512 Methylobacterium extorquens CM4 MxaA protein YP_002423216.1 4780094 R 440085 CDS YP_002423217.1 218532401 7118478 complement(4781023..4781892) 1 NC_011757.1 KEGG: mex:Mext_4145 hypothetical protein; hypothetical protein 4781892 7118478 Mchl_4513 Methylobacterium extorquens CM4 hypothetical protein YP_002423217.1 4781023 R 440085 CDS YP_002423218.1 218532402 7118479 complement(4781889..4782920) 1 NC_011757.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase AAA; SMART: AAA ATPase; KEGG: mex:Mext_4146 ATPase; ATPase AAA 4782920 7118479 Mchl_4514 Methylobacterium extorquens CM4 ATPase AAA YP_002423218.1 4781889 R 440085 CDS YP_002423219.1 218532403 7118480 complement(4783069..4783359) 1 NC_011757.1 PFAM: methanol dehydrogenase subunit beta; KEGG: mex:Mext_4147 methanol dehydrogenase subunit beta; methanol dehydrogenase subunit beta 4783359 7118480 Mchl_4515 Methylobacterium extorquens CM4 methanol dehydrogenase subunit beta YP_002423219.1 4783069 R 440085 CDS YP_002423220.1 218532404 7118481 complement(4783465..4784058) 1 NC_011757.1 PFAM: cytochrome C class I; KEGG: mex:Mext_4148 cytochrome c class I; cytochrome C class I 4784058 7118481 Mchl_4516 Methylobacterium extorquens CM4 cytochrome C class I YP_002423220.1 4783465 R 440085 CDS YP_002423221.1 218532405 7118482 complement(4784201..4785103) 1 NC_011757.1 PFAM: extracellular solute-binding protein family 3; KEGG: mex:Mext_4149 extracellular solute-binding protein; family 3 extracellular solute-binding protein 4785103 7118482 Mchl_4517 Methylobacterium extorquens CM4 family 3 extracellular solute-binding protein YP_002423221.1 4784201 R 440085 CDS YP_002423222.1 218532406 7118483 complement(4785368..4787248) 1 NC_011757.1 TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: pyrrolo-quinoline quinone; KEGG: mex:Mext_4150 methanol/ethanol family PQQ-dependent dehydrogenase; methanol/ethanol family PQQ-dependent dehydrogenase 4787248 7118483 Mchl_4518 Methylobacterium extorquens CM4 methanol/ethanol family PQQ-dependent dehydrogenase YP_002423222.1 4785368 R 440085 CDS YP_002423223.1 218532407 7118484 4787619..4788524 1 NC_011757.1 KEGG: mex:Mext_4151 hypothetical protein; hypothetical protein 4788524 7118484 Mchl_4519 Methylobacterium extorquens CM4 hypothetical protein YP_002423223.1 4787619 D 440085 CDS YP_002423224.1 218532408 7118485 4788674..4788871 1 NC_011757.1 KEGG: mex:Mext_4152 hypothetical protein; hypothetical protein 4788871 7118485 Mchl_4520 Methylobacterium extorquens CM4 hypothetical protein YP_002423224.1 4788674 D 440085 CDS YP_002423225.1 218532409 7118486 complement(4788901..4789635) 1 NC_011757.1 KEGG: mex:Mext_4153 hypothetical protein; hypothetical protein 4789635 7118486 Mchl_4521 Methylobacterium extorquens CM4 hypothetical protein YP_002423225.1 4788901 R 440085 CDS YP_002423226.1 218532410 7118487 4789954..4790853 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_4154 beta-lactamase domain-containing protein; beta-lactamase 4790853 7118487 Mchl_4522 Methylobacterium extorquens CM4 beta-lactamase YP_002423226.1 4789954 D 440085 CDS YP_002423227.1 218532411 7118488 4790865..4791392 1 NC_011757.1 KEGG: mex:Mext_4155 hypothetical protein; hypothetical protein 4791392 7118488 Mchl_4523 Methylobacterium extorquens CM4 hypothetical protein YP_002423227.1 4790865 D 440085 CDS YP_002423228.1 218532412 7118489 4791389..4791568 1 NC_011757.1 KEGG: mpo:Mpop_4638 hypothetical protein; hypothetical protein 4791568 7118489 Mchl_4524 Methylobacterium extorquens CM4 hypothetical protein YP_002423228.1 4791389 D 440085 CDS YP_002423229.1 218532413 7118490 4791787..4793172 1 NC_011757.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; transferase hexapeptide repeat containing protein; nucleotidyl transferase; KEGG: mex:Mext_4156 UDP-N-acetylglucosamine pyrophosphorylase; UDP-N-acetylglucosamine pyrophosphorylase 4793172 7118490 Mchl_4525 Methylobacterium extorquens CM4 UDP-N-acetylglucosamine pyrophosphorylase YP_002423229.1 4791787 D 440085 CDS YP_002423230.1 218532414 7118491 4793357..4795183 1 NC_011757.1 TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase class-II; sugar isomerase (SIS); KEGG: mex:Mext_4157 glucosamine--fructose-6-phosphate aminotransferase, isomerizing; glucosamine/fructose-6-phosphate aminotransferase 4795183 7118491 Mchl_4526 Methylobacterium extorquens CM4 glucosamine/fructose-6-phosphate aminotransferase YP_002423230.1 4793357 D 440085 CDS YP_002423231.1 218532415 7118492 complement(4795245..4795679) 1 NC_011757.1 PFAM: protein of unknown function DUF336; KEGG: mex:Mext_4158 hypothetical protein; hypothetical protein 4795679 7118492 Mchl_4527 Methylobacterium extorquens CM4 hypothetical protein YP_002423231.1 4795245 R 440085 CDS YP_002423232.1 218532416 7118493 4795861..4796706 1 NC_011757.1 PFAM: protein of unknown function DUF502; KEGG: mex:Mext_4159 hypothetical protein; hypothetical protein 4796706 7118493 Mchl_4528 Methylobacterium extorquens CM4 hypothetical protein YP_002423232.1 4795861 D 440085 CDS YP_002423233.1 218532417 7118494 complement(4796729..4797055) 1 NC_011757.1 KEGG: mex:Mext_4160 hypothetical protein; hypothetical protein 4797055 7118494 Mchl_4529 Methylobacterium extorquens CM4 hypothetical protein YP_002423233.1 4796729 R 440085 CDS YP_002423234.1 218532418 7118495 complement(4797411..4799600) 1 NC_011757.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4799600 7118495 Mchl_4530 Methylobacterium extorquens CM4 ATP-dependent DNA helicase RecG YP_002423234.1 4797411 R 440085 CDS YP_002423235.1 218532419 7118496 4799792..4800088 1 NC_011757.1 PFAM: protein of unknown function DUF339; KEGG: mex:Mext_4162 hypothetical protein; hypothetical protein 4800088 7118496 Mchl_4531 Methylobacterium extorquens CM4 hypothetical protein YP_002423235.1 4799792 D 440085 CDS YP_002423236.1 218532420 7118497 4800302..4803892 1 NC_011757.1 KEGG: mex:Mext_4163 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase; SMART: DEAD-like helicases; transcription-repair coupling factor 4803892 7118497 Mchl_4532 Methylobacterium extorquens CM4 transcription-repair coupling factor YP_002423236.1 4800302 D 440085 CDS YP_002423237.1 218532421 7118498 4804269..4804478 1 NC_011757.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: mex:Mext_4164 cold-shock protein DNA-binding; cold-shock DNA-binding domain-containing protein 4804478 7118498 Mchl_4533 Methylobacterium extorquens CM4 cold-shock DNA-binding domain-containing protein YP_002423237.1 4804269 D 440085 CDS YP_002423238.1 218532422 7118499 4804581..4804949 1 NC_011757.1 KEGG: mex:Mext_4165 hypothetical protein; hypothetical protein 4804949 7118499 Mchl_4534 Methylobacterium extorquens CM4 hypothetical protein YP_002423238.1 4804581 D 440085 CDS YP_002423239.1 218532423 7118500 4805128..4805325 1 NC_011757.1 KEGG: mex:Mext_4166 hypothetical protein; hypothetical protein 4805325 7118500 Mchl_4535 Methylobacterium extorquens CM4 hypothetical protein YP_002423239.1 4805128 D 440085 CDS YP_002423240.1 218532424 7118501 complement(4805392..4805733) 1 NC_011757.1 KEGG: mpo:Mpop_4680 hypothetical protein; hypothetical protein 4805733 7118501 Mchl_4536 Methylobacterium extorquens CM4 hypothetical protein YP_002423240.1 4805392 R 440085 CDS YP_002423241.1 218532425 7118502 complement(4805992..4807392) 1 NC_011757.1 KEGG: mex:Mext_4168 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein 4807392 7118502 Mchl_4537 Methylobacterium extorquens CM4 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein YP_002423241.1 4805992 R 440085 CDS YP_002423242.1 218532426 7118503 4807690..4808943 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_4169 ATPase domain-containing protein; histidine kinase 4808943 7118503 Mchl_4538 Methylobacterium extorquens CM4 histidine kinase YP_002423242.1 4807690 D 440085 CDS YP_002423243.1 218532427 7118504 4809144..4809506 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4170 response regulator receiver; response regulator receiver protein 4809506 7118504 Mchl_4539 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423243.1 4809144 D 440085 CDS YP_002423244.1 218532428 7118505 complement(4809562..4811193) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_4171 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 4811193 7118505 Mchl_4540 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002423244.1 4809562 R 440085 CDS YP_002423245.1 218532429 7118506 complement(4811332..4811526) 1 NC_011757.1 KEGG: mpo:Mpop_4685 hypothetical protein; hypothetical protein 4811526 7118506 Mchl_4541 Methylobacterium extorquens CM4 hypothetical protein YP_002423245.1 4811332 R 440085 CDS YP_002423246.1 218532430 7118507 4811776..4813584 1 NC_011757.1 PFAM: glycosyl transferase family 39; KEGG: mex:Mext_4173 glycosyl transferase; glycosyl transferase family protein 4813584 7118507 Mchl_4542 Methylobacterium extorquens CM4 glycosyl transferase family protein YP_002423246.1 4811776 D 440085 CDS YP_002423247.1 218532431 7118508 4813581..4814354 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_4174 glycosyl transferase; family 2 glycosyl transferase 4814354 7118508 Mchl_4543 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423247.1 4813581 D 440085 CDS YP_002423248.1 218532432 7118509 4814359..4814688 1 NC_011757.1 PFAM: lipid A biosynthesis domain protein; KEGG: mex:Mext_4175 lipid A biosynthesis domain-containing protein; lipid A biosynthesis domain-containing protein 4814688 7118509 Mchl_4544 Methylobacterium extorquens CM4 lipid A biosynthesis domain-containing protein YP_002423248.1 4814359 D 440085 CDS YP_002423249.1 218532433 7118510 4814704..4815171 1 NC_011757.1 KEGG: mex:Mext_4176 hypothetical protein; hypothetical protein 4815171 7118510 Mchl_4545 Methylobacterium extorquens CM4 hypothetical protein YP_002423249.1 4814704 D 440085 CDS YP_002423250.1 218532434 7118511 complement(4815172..4816683) 1 NC_011757.1 KEGG: mex:Mext_4177 cyclohexanone monooxygenase; cyclohexanone monooxygenase 4816683 7118511 Mchl_4546 Methylobacterium extorquens CM4 cyclohexanone monooxygenase YP_002423250.1 4815172 R 440085 CDS YP_002423251.1 218532435 7116961 complement(4816680..4817594) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: mex:Mext_4178 alpha/beta hydrolase domain-containing protein; alpha/beta hydrolase fold-3 domain-containing protein 4817594 7116961 Mchl_4547 Methylobacterium extorquens CM4 alpha/beta hydrolase fold-3 domain-containing protein YP_002423251.1 4816680 R 440085 CDS YP_002423252.1 218532436 7117943 complement(4817597..4818421) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4179 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4818421 7117943 Mchl_4548 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423252.1 4817597 R 440085 CDS YP_002423253.1 218532437 7117944 complement(4818429..4819925) 1 NC_011757.1 PFAM: protein of unknown function UPF0061; KEGG: mex:Mext_4180 hypothetical protein; hypothetical protein 4819925 7117944 Mchl_4549 Methylobacterium extorquens CM4 hypothetical protein YP_002423253.1 4818429 R 440085 CDS YP_002423254.1 218532438 7117945 4820033..4820272 1 NC_011757.1 PFAM: protein of unknown function DUF433; KEGG: mpo:Mpop_4945 protein of unknown function DUF433; hypothetical protein 4820272 7117945 Mchl_4550 Methylobacterium extorquens CM4 hypothetical protein YP_002423254.1 4820033 D 440085 CDS YP_002423255.1 218532439 7117946 4820279..4820680 1 NC_011757.1 KEGG: rrs:RoseRS_0674 hypothetical protein; hypothetical protein 4820680 7117946 Mchl_4551 Methylobacterium extorquens CM4 hypothetical protein YP_002423255.1 4820279 D 440085 CDS YP_002423256.1 218532440 7117947 4820628..4821629 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_4181 hypothetical protein; hypothetical protein 4821629 7117947 Mchl_4552 Methylobacterium extorquens CM4 hypothetical protein YP_002423256.1 4820628 D 440085 CDS YP_002423257.1 218532441 7117948 4821911..4822966 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: mex:Mext_4182 histidine kinase dimerisation/phosphoacceptor; signal transduction histidine kinase 4822966 7117948 Mchl_4553 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002423257.1 4821911 D 440085 CDS YP_002423258.1 218532442 7117949 4823327..4824130 1 NC_011757.1 PFAM: lipolytic protein G-D-S-L family; KEGG: mex:Mext_4183 GDSL family lipase; G-D-S-L family lipolytic protein 4824130 7117949 Mchl_4554 Methylobacterium extorquens CM4 G-D-S-L family lipolytic protein YP_002423258.1 4823327 D 440085 CDS YP_002423259.1 218532443 7117950 4824198..4824590 1 NC_011757.1 KEGG: mex:Mext_4184 hypothetical protein; hypothetical protein 4824590 7117950 Mchl_4555 Methylobacterium extorquens CM4 hypothetical protein YP_002423259.1 4824198 D 440085 CDS YP_002423260.1 218532444 7117951 complement(4824699..4825517) 1 NC_011757.1 KEGG: mex:Mext_4185 beta-lactamase-like protein; beta-lactamase-like protein 4825517 7117951 Mchl_4556 Methylobacterium extorquens CM4 beta-lactamase-like protein YP_002423260.1 4824699 R 440085 CDS YP_002423261.1 218532445 7117952 complement(4825534..4826331) 1 NC_011757.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: mex:Mext_4186 TatD family hydrolase; hydrolase, TatD family 4826331 7117952 Mchl_4557 Methylobacterium extorquens CM4 hydrolase, TatD family YP_002423261.1 4825534 R 440085 CDS YP_002423262.1 218532446 7117953 complement(4826381..4827949) 1 NC_011757.1 TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); KEGG: mex:Mext_4187 methionyl-tRNA synthetase; methionyl-tRNA synthetase 4827949 7117953 Mchl_4558 Methylobacterium extorquens CM4 methionyl-tRNA synthetase YP_002423262.1 4826381 R 440085 CDS YP_002423263.1 218532447 7117954 complement(4828175..4828390) 1 NC_011757.1 KEGG: mex:Mext_4188 hypothetical protein; hypothetical protein 4828390 7117954 Mchl_4559 Methylobacterium extorquens CM4 hypothetical protein YP_002423263.1 4828175 R 440085 CDS YP_002423264.1 218532448 7117955 4828688..4828888 1 NC_011757.1 KEGG: mex:Mext_4189 hypothetical protein; hypothetical protein 4828888 7117955 Mchl_4560 Methylobacterium extorquens CM4 hypothetical protein YP_002423264.1 4828688 D 440085 CDS YP_002423265.1 218532449 7117956 complement(4828936..4830018) 1 NC_011757.1 KEGG: mex:Mext_4190 DNA-directed DNA polymerase; DNA-directed DNA polymerase 4830018 7117956 Mchl_4561 Methylobacterium extorquens CM4 DNA-directed DNA polymerase YP_002423265.1 4828936 R 440085 CDS YP_002423266.1 218532450 7117957 complement(4830008..4830742) 1 NC_011757.1 PFAM: thymidylate kinase; KEGG: mex:Mext_4191 dTMP kinase; dTMP kinase 4830742 7117957 Mchl_4562 Methylobacterium extorquens CM4 dTMP kinase YP_002423266.1 4830008 R 440085 CDS YP_002423267.1 218532451 7117958 complement(4830797..4831576) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4192 ornithine carbamoyltransferase; ornithine carbamoyltransferase 4831576 7117958 Mchl_4563 Methylobacterium extorquens CM4 ornithine carbamoyltransferase YP_002423267.1 4830797 R 440085 CDS YP_002423268.1 218532452 7117959 complement(4831573..4832577) 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4193 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4832577 7117959 Mchl_4564 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002423268.1 4831573 R 440085 CDS YP_002423269.1 218532453 7117960 complement(4832574..4833659) 1 NC_011757.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: mex:Mext_4194 ABC transporter; ABC transporter 4833659 7117960 Mchl_4565 Methylobacterium extorquens CM4 ABC transporter YP_002423269.1 4832574 R 440085 CDS YP_002423270.1 218532454 7117961 complement(4833748..4834452) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_4195 cyclic nucleotide-binding; cyclic nucleotide-binding protein 4834452 7117961 Mchl_4566 Methylobacterium extorquens CM4 cyclic nucleotide-binding protein YP_002423270.1 4833748 R 440085 CDS YP_002423271.1 218532455 7117962 4835252..4837954 1 NC_011757.1 KEGG: mex:Mext_4197 hypothetical protein; hypothetical protein 4837954 7117962 Mchl_4567 Methylobacterium extorquens CM4 hypothetical protein YP_002423271.1 4835252 D 440085 CDS YP_002423272.1 218532456 7117963 4838348..4838737 1 NC_011757.1 KEGG: mex:Mext_4198 hypothetical protein; hypothetical protein 4838737 7117963 Mchl_4568 Methylobacterium extorquens CM4 hypothetical protein YP_002423272.1 4838348 D 440085 CDS YP_002423273.1 218532457 7117964 complement(4838775..4840076) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4199 major facilitator transporter; major facilitator superfamily protein 4840076 7117964 Mchl_4569 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423273.1 4838775 R 440085 CDS YP_002423274.1 218532458 7117965 complement(4840166..4841341) 1 NC_011757.1 PFAM: aminotransferase class V; KEGG: mex:Mext_4200 aminotransferase class V; serine--glyoxylate transaminase 4841341 7117965 Mchl_4570 Methylobacterium extorquens CM4 serine--glyoxylate transaminase YP_002423274.1 4840166 R 440085 CDS YP_002423275.1 218532459 7117966 4841493..4842284 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_4201 regulatory protein GntR HTH; GntR family transcriptional regulator 4842284 7117966 Mchl_4571 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002423275.1 4841493 D 440085 CDS YP_002423276.1 218532460 7117967 4842340..4843116 1 NC_011757.1 KEGG: mex:Mext_4202 hydroxypyruvate isomerase; TIGRFAM: hydroxypyruvate isomerase; PFAM: xylose isomerase; hydroxypyruvate isomerase 4843116 7117967 Mchl_4572 Methylobacterium extorquens CM4 hydroxypyruvate isomerase YP_002423276.1 4842340 D 440085 CDS YP_002423277.1 218532461 7117968 complement(4843232..4844104) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_4203 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4844104 7117968 Mchl_4573 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423277.1 4843232 R 440085 CDS YP_002423278.1 218532462 7117969 complement(4844181..4847153) 1 NC_011757.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; FAD linked oxidase; KEGG: mex:Mext_4204 D-lactate dehydrogenase (cytochrome); D-lactate dehydrogenase (cytochrome) 4847153 7117969 Mchl_4574 Methylobacterium extorquens CM4 D-lactate dehydrogenase (cytochrome) YP_002423278.1 4844181 R 440085 CDS YP_002423279.1 218532463 7117970 complement(4847335..4848699) 1 NC_011757.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: mex:Mext_4205 polyhydroxyalkanoate depolymerase, intracellular; polyhydroxyalkanoate depolymerase, intracellular 4848699 7117970 Mchl_4575 Methylobacterium extorquens CM4 polyhydroxyalkanoate depolymerase, intracellular YP_002423279.1 4847335 R 440085 CDS YP_002423280.1 218532464 7117971 complement(4849000..4850433) 1 NC_011757.1 PFAM: aldehyde dehydrogenase; KEGG: mex:Mext_4206 aldehyde dehydrogenase; aldehyde dehydrogenase 4850433 7117971 Mchl_4576 Methylobacterium extorquens CM4 aldehyde dehydrogenase YP_002423280.1 4849000 R 440085 CDS YP_002423281.1 218532465 7117973 4851240..4852715 1 NC_011757.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: rpc:RPC_0674 lipopolysaccharide biosynthesis; lipopolysaccharide biosynthesis protein 4852715 7117973 Mchl_4578 Methylobacterium extorquens CM4 lipopolysaccharide biosynthesis protein YP_002423281.1 4851240 D 440085 CDS YP_002423282.1 218532466 7117974 4852797..4854143 1 NC_011757.1 PFAM: O-antigen polymerase; KEGG: rsh:Rsph17029_3696 O-antigen polymerase; O-antigen polymerase 4854143 7117974 Mchl_4579 Methylobacterium extorquens CM4 O-antigen polymerase YP_002423282.1 4852797 D 440085 CDS YP_002423283.1 218532467 7117976 complement(4854709..4855014) 1 NC_011757.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: mex:Mext_4210 surface presentation of antigens (SpoA) protein; surface presentation of antigens (SPOA) protein 4855014 7117976 Mchl_4580 Methylobacterium extorquens CM4 surface presentation of antigens (SPOA) protein YP_002423283.1 4854709 R 440085 CDS YP_002423284.1 218532468 7117977 4855073..4855807 1 NC_011757.1 TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; KEGG: mex:Mext_4211 lipoate-protein ligase B; lipoate-protein ligase B 4855807 7117977 Mchl_4581 Methylobacterium extorquens CM4 lipoate-protein ligase B YP_002423284.1 4855073 D 440085 CDS YP_002423285.1 218532469 7117978 complement(4855934..4857094) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_4212 glycosyl transferase; family 2 glycosyl transferase 4857094 7117978 Mchl_4582 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423285.1 4855934 R 440085 CDS YP_002423286.1 218532470 7117979 4857340..4857786 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_4213 hypothetical protein; hypothetical protein 4857786 7117979 Mchl_4583 Methylobacterium extorquens CM4 hypothetical protein YP_002423286.1 4857340 D 440085 CDS YP_002423287.1 218532471 7117980 complement(4857808..4859766) 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_4214 hypothetical protein; hypothetical protein 4859766 7117980 Mchl_4584 Methylobacterium extorquens CM4 hypothetical protein YP_002423287.1 4857808 R 440085 CDS YP_002423288.1 218532472 7117981 complement(4859995..4860369) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4215 response regulator receiver; response regulator receiver protein 4860369 7117981 Mchl_4585 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423288.1 4859995 R 440085 CDS YP_002423289.1 218532473 7117982 4860542..4861903 1 NC_011757.1 PFAM: pentapeptide repeat protein; KEGG: mex:Mext_4216 pentapeptide repeat-containing protein; pentapeptide repeat-containing protein 4861903 7117982 Mchl_4586 Methylobacterium extorquens CM4 pentapeptide repeat-containing protein YP_002423289.1 4860542 D 440085 CDS YP_002423290.1 218532474 7117983 4861987..4864398 1 NC_011757.1 KEGG: mex:Mext_4217 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 4864398 7117983 Mchl_4587 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002423290.1 4861987 D 440085 CDS YP_002423291.1 218532475 7117985 4866050..4866937 1 NC_011757.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_4219 hypothetical protein; hypothetical protein 4866937 7117985 Mchl_4589 Methylobacterium extorquens CM4 hypothetical protein YP_002423291.1 4866050 D 440085 CDS YP_002423292.1 218532476 7117986 complement(4866950..4867684) 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: mex:Mext_4220 response regulator receiver; LuxR family transcriptional regulator 4867684 7117986 Mchl_4590 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423292.1 4866950 R 440085 CDS YP_002423293.1 218532477 7117987 complement(4867810..4868373) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_4221 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 4868373 7117987 Mchl_4591 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002423293.1 4867810 R 440085 CDS YP_002423294.1 218532478 7117988 4868515..4868958 1 NC_011757.1 PFAM: protein of unknown function DUF983; KEGG: mex:Mext_4222 hypothetical protein; hypothetical protein 4868958 7117988 Mchl_4592 Methylobacterium extorquens CM4 hypothetical protein YP_002423294.1 4868515 D 440085 CDS YP_002423295.1 218532479 7117989 complement(4869031..4870770) 1 NC_011757.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: mex:Mext_4223 L-lactate transport; L-lactate transport 4870770 7117989 Mchl_4593 Methylobacterium extorquens CM4 L-lactate transport YP_002423295.1 4869031 R 440085 CDS YP_002423296.1 218532480 7117990 4871143..4872066 1 NC_011757.1 PFAM: manganese containing catalase; KEGG: mex:Mext_4224 manganese containing catalase; manganese containing catalase 4872066 7117990 Mchl_4594 Methylobacterium extorquens CM4 manganese containing catalase YP_002423296.1 4871143 D 440085 CDS YP_002423297.1 218532481 7117991 complement(4872131..4873027) 1 NC_011757.1 PFAM: Squalene/phytoene synthase; KEGG: mex:Mext_4225 squalene/phytoene synthase; Squalene/phytoene synthase 4873027 7117991 Mchl_4595 Methylobacterium extorquens CM4 Squalene/phytoene synthase YP_002423297.1 4872131 R 440085 CDS YP_002423298.1 218532482 7117992 complement(4873161..4873556) 1 NC_011757.1 PFAM: protein of unknown function DUF498; KEGG: mex:Mext_4226 hypothetical protein; hypothetical protein 4873556 7117992 Mchl_4596 Methylobacterium extorquens CM4 hypothetical protein YP_002423298.1 4873161 R 440085 CDS YP_002423299.1 218532483 7117993 complement(4873681..4874625) 1 NC_011757.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: mex:Mext_4227 protein-export membrane protein SecF; protein-export membrane protein SecF 4874625 7117993 Mchl_4597 Methylobacterium extorquens CM4 protein-export membrane protein SecF YP_002423299.1 4873681 R 440085 CDS YP_002423300.1 218532484 7117994 complement(4874725..4876323) 1 NC_011757.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: mex:Mext_4228 protein-export membrane protein SecD; protein-export membrane protein SecD 4876323 7117994 Mchl_4598 Methylobacterium extorquens CM4 protein-export membrane protein SecD YP_002423300.1 4874725 R 440085 CDS YP_002423301.1 218532485 7117995 complement(4876391..4876723) 1 NC_011757.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mex:Mext_4229 preprotein translocase, YajC subunit; preprotein translocase subunit YajC 4876723 7117995 Mchl_4599 Methylobacterium extorquens CM4 preprotein translocase subunit YajC YP_002423301.1 4876391 R 440085 CDS YP_002423302.1 218532486 7117996 4877209..4878099 1 NC_011757.1 PFAM: protein of unknown function DUF815; KEGG: mex:Mext_4230 hypothetical protein; hypothetical protein 4878099 7117996 Mchl_4600 Methylobacterium extorquens CM4 hypothetical protein YP_002423302.1 4877209 D 440085 CDS YP_002423303.1 218532487 7117997 complement(4878223..4879590) 1 NC_011757.1 PFAM: peptidase M23; KEGG: mex:Mext_4231 peptidase M23B; peptidase M23 4879590 7117997 Mchl_4601 Methylobacterium extorquens CM4 peptidase M23 YP_002423303.1 4878223 R 440085 CDS YP_002423304.1 218532488 7117998 complement(4879794..4880492) 1 NC_011757.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; KEGG: mex:Mext_4232 protein-L-isoaspartate(D-aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 4880492 7117998 Mchl_4602 Methylobacterium extorquens CM4 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_002423304.1 4879794 R 440085 CDS YP_002423305.1 218532489 7117999 complement(4880517..4881281) 1 NC_011757.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 4881281 surE 7117999 surE Methylobacterium extorquens CM4 stationary phase survival protein SurE YP_002423305.1 4880517 R 440085 CDS YP_002423306.1 218532490 7118000 complement(4881281..4882567) 1 NC_011757.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 4882567 7118000 Mchl_4604 Methylobacterium extorquens CM4 seryl-tRNA synthetase YP_002423306.1 4881281 R 440085 CDS YP_002423307.1 218532491 7118001 complement(4883445..4883963) 1 NC_011757.1 PFAM: regulatory protein MarR; KEGG: mex:Mext_4235 regulatory protein MarR; MarR family transcriptional regulator 4883963 7118001 Mchl_4605 Methylobacterium extorquens CM4 MarR family transcriptional regulator YP_002423307.1 4883445 R 440085 CDS YP_002423308.1 218532492 7118002 complement(4884125..4884592) 1 NC_011757.1 KEGG: mex:Mext_4236 hypothetical protein; hypothetical protein 4884592 7118002 Mchl_4606 Methylobacterium extorquens CM4 hypothetical protein YP_002423308.1 4884125 R 440085 CDS YP_002423309.1 218532493 7118003 complement(4884589..4885923) 1 NC_011757.1 PFAM: enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_4237 enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase 4885923 7118003 Mchl_4607 Methylobacterium extorquens CM4 enoyl-CoA hydratase/isomerase YP_002423309.1 4884589 R 440085 CDS YP_002423310.1 218532494 7118004 4886407..4887462 1 NC_011757.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 4887462 7118004 Mchl_4608 Methylobacterium extorquens CM4 delta-aminolevulinic acid dehydratase YP_002423310.1 4886407 D 440085 CDS YP_002423311.1 218532495 7118005 4887488..4887889 1 NC_011757.1 KEGG: mex:Mext_4239 hypothetical protein; hypothetical protein 4887889 7118005 Mchl_4609 Methylobacterium extorquens CM4 hypothetical protein YP_002423311.1 4887488 D 440085 CDS YP_002423312.1 218532496 7118006 4888003..4888497 1 NC_011757.1 PFAM: RDD domain containing protein; KEGG: mex:Mext_4240 RDD domain-containing protein; RDD domain-containing protein 4888497 7118006 Mchl_4610 Methylobacterium extorquens CM4 RDD domain-containing protein YP_002423312.1 4888003 D 440085 CDS YP_002423313.1 218532497 7118007 4888636..4889382 1 NC_011757.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 4889382 7118007 Mchl_4611 Methylobacterium extorquens CM4 arginyl-tRNA-protein transferase YP_002423313.1 4888636 D 440085 CDS YP_002423314.1 218532498 7118008 4889469..4889795 1 NC_011757.1 TIGRFAM: addiction module killer protein; PFAM: protein of unknown function DUF891; KEGG: mex:Mext_4242 addiction module killer protein; addiction module killer protein 4889795 7118008 Mchl_4612 Methylobacterium extorquens CM4 addiction module killer protein YP_002423314.1 4889469 D 440085 CDS YP_002423315.1 218532499 7118009 4889795..4890112 1 NC_011757.1 KEGG: mex:Mext_4243 hypothetical protein; transcriptional regulator 4890112 7118009 Mchl_4613 Methylobacterium extorquens CM4 transcriptional regulator YP_002423315.1 4889795 D 440085 CDS YP_002423316.1 218532500 7118010 complement(4890147..4890710) 1 NC_011757.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: mex:Mext_4244 hexapaptide repeat-containing transferase; transferase 4890710 7118010 Mchl_4614 Methylobacterium extorquens CM4 transferase YP_002423316.1 4890147 R 440085 CDS YP_002423317.1 218532501 7118011 complement(4890737..4891642) 1 NC_011757.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: mex:Mext_4245 protein of unknown function zinc metallopeptidase; hypothetical protein 4891642 7118011 Mchl_4615 Methylobacterium extorquens CM4 hypothetical protein YP_002423317.1 4890737 R 440085 CDS YP_002423318.1 218532502 7117779 complement(4891748..4892752) 1 NC_011757.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: uracil-DNA glycosylase superfamily; KEGG: mex:Mext_4246 phage SPO1 DNA polymerase-related protein; phage SPO1 DNA polymerase-like protein 4892752 7117779 Mchl_4616 Methylobacterium extorquens CM4 phage SPO1 DNA polymerase-like protein YP_002423318.1 4891748 R 440085 CDS YP_002423319.1 218532503 7115185 4892973..4894646 1 NC_011757.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: mex:Mext_4247 electron-transferring-flavoprotein dehydrogenase; electron-transferring-flavoprotein dehydrogenase 4894646 7115185 Mchl_4617 Methylobacterium extorquens CM4 electron-transferring-flavoprotein dehydrogenase YP_002423319.1 4892973 D 440085 CDS YP_002423320.1 218532504 7115186 complement(4894740..4895729) 1 NC_011757.1 PFAM: peptidase S58 DmpA; KEGG: mex:Mext_4248 peptidase S58 DmpA; peptidase S58 DmpA 4895729 7115186 Mchl_4618 Methylobacterium extorquens CM4 peptidase S58 DmpA YP_002423320.1 4894740 R 440085 CDS YP_002423321.1 218532505 7115187 complement(4895726..4896610) 1 NC_011757.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_4249 transporter DMT superfamily protein; RarD protein, DMT superfamily transporter 4896610 7115187 Mchl_4619 Methylobacterium extorquens CM4 RarD protein, DMT superfamily transporter YP_002423321.1 4895726 R 440085 CDS YP_002423322.1 218532506 7115188 complement(4896668..4896955) 1 NC_011757.1 KEGG: mex:Mext_4250 hypothetical protein; hypothetical protein 4896955 7115188 Mchl_4620 Methylobacterium extorquens CM4 hypothetical protein YP_002423322.1 4896668 R 440085 CDS YP_002423323.1 218532507 7115189 4897014..4897262 1 NC_011757.1 KEGG: mex:Mext_4251 hypothetical protein; hypothetical protein 4897262 7115189 Mchl_4621 Methylobacterium extorquens CM4 hypothetical protein YP_002423323.1 4897014 D 440085 CDS YP_002423324.1 218532508 7115190 4897359..4898546 1 NC_011757.1 TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mex:Mext_4252 cystathionine beta-lyase; cystathionine beta-lyase 4898546 7115190 Mchl_4622 Methylobacterium extorquens CM4 cystathionine beta-lyase YP_002423324.1 4897359 D 440085 CDS YP_002423325.1 218532509 7115191 4898946..4900394 1 NC_011757.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: met:M446_6753 hypothetical protein; hypothetical protein 4900394 7115191 Mchl_4623 Methylobacterium extorquens CM4 hypothetical protein YP_002423325.1 4898946 D 440085 CDS YP_002423326.1 218532510 7115192 complement(4900581..4901177) 1 NC_011757.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mex:Mext_4258 pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 4901177 7115192 Mchl_4624 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002423326.1 4900581 R 440085 CDS YP_002423327.1 218532511 7115193 4901585..4904863 1 NC_011757.1 KEGG: mex:Mext_4259 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC sensor hybrid histidine kinase 4904863 7115193 Mchl_4625 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002423327.1 4901585 D 440085 CDS YP_002423328.1 218532512 7115194 complement(4904897..4907125) 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_4260 glycosyl transferase; family 2 glycosyl transferase 4907125 7115194 Mchl_4626 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423328.1 4904897 R 440085 CDS YP_002423329.1 218532513 7115195 complement(4907234..4907560) 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_4261 cupin 2 domain-containing protein; cupin 4907560 7115195 Mchl_4627 Methylobacterium extorquens CM4 cupin YP_002423329.1 4907234 R 440085 CDS YP_002423330.1 218532514 7115196 4907683..4907844 1 NC_011757.1 KEGG: predicted protein; hypothetical protein 4907844 7115196 Mchl_4628 Methylobacterium extorquens CM4 hypothetical protein YP_002423330.1 4907683 D 440085 CDS YP_002423331.1 218532515 7115197 4907849..4908499 1 NC_011757.1 KEGG: mex:Mext_4262 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; methyltransferase small; methyltransferase type 11; methyltransferase type 12; protein-L-isoaspartate O-methyltransferase 4908499 7115197 Mchl_4629 Methylobacterium extorquens CM4 protein-L-isoaspartate O-methyltransferase YP_002423331.1 4907849 D 440085 CDS YP_002423332.1 218532516 7115198 4908691..4909179 1 NC_011757.1 PFAM: heat shock protein Hsp20; KEGG: mex:Mext_4263 heat shock protein HSP20; heat shock protein Hsp20 4909179 7115198 Mchl_4630 Methylobacterium extorquens CM4 heat shock protein Hsp20 YP_002423332.1 4908691 D 440085 CDS YP_002423333.1 218532517 7115199 4909284..4909781 1 NC_011757.1 KEGG: mex:Mext_4264 hypothetical protein; hypothetical protein 4909781 7115199 Mchl_4631 Methylobacterium extorquens CM4 hypothetical protein YP_002423333.1 4909284 D 440085 CDS YP_002423334.1 218532518 7115200 complement(4909844..4911829) 1 NC_011757.1 TIGRFAM: DNA mismatch repair protein MutL; PFAM: ATP-binding region ATPase domain protein; DNA mismatch repair protein domain protein; MutL dimerisation; KEGG: mex:Mext_4265 DNA mismatch repair protein MutL; DNA mismatch repair protein MutL 4911829 7115200 Mchl_4632 Methylobacterium extorquens CM4 DNA mismatch repair protein MutL YP_002423334.1 4909844 R 440085 CDS YP_002423335.1 218532519 7115201 complement(4912046..4913272) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_4266 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 4913272 7115201 Mchl_4633 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002423335.1 4912046 R 440085 CDS YP_002423336.1 218532520 7115202 4913412..4915277 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_4267 ABC transporter; ABC transporter 4915277 7115202 Mchl_4634 Methylobacterium extorquens CM4 ABC transporter YP_002423336.1 4913412 D 440085 CDS YP_002423337.1 218532521 7115203 4915677..4916708 1 NC_011757.1 KEGG: mex:Mext_4268 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4916708 7115203 Mchl_4635 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002423337.1 4915677 D 440085 CDS YP_002423338.1 218532522 7115204 complement(4916684..4917400) 1 NC_011757.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: mex:Mext_4269 deaminase-reductase domain-containing protein; bifunctional deaminase-reductase domain-containing protein 4917400 7115204 Mchl_4636 Methylobacterium extorquens CM4 bifunctional deaminase-reductase domain-containing protein YP_002423338.1 4916684 R 440085 CDS YP_002423339.1 218532523 7115205 4917549..4918001 1 NC_011757.1 PFAM: OsmC family protein; KEGG: mex:Mext_4270 OsmC family protein; OsmC family protein 4918001 7115205 Mchl_4637 Methylobacterium extorquens CM4 OsmC family protein YP_002423339.1 4917549 D 440085 CDS YP_002423340.1 218532524 7115206 4918071..4918508 1 NC_011757.1 PFAM: protein of unknown function DUF336; KEGG: mex:Mext_4271 hypothetical protein; hypothetical protein 4918508 7115206 Mchl_4638 Methylobacterium extorquens CM4 hypothetical protein YP_002423340.1 4918071 D 440085 CDS YP_002423341.1 218532525 7115207 4918875..4920473 1 NC_011757.1 PFAM: extracellular solute-binding protein family 5; KEGG: mex:Mext_4272 extracellular solute-binding protein; family 5 extracellular solute-binding protein 4920473 7115207 Mchl_4639 Methylobacterium extorquens CM4 family 5 extracellular solute-binding protein YP_002423341.1 4918875 D 440085 CDS YP_002423342.1 218532526 7115208 4920470..4921393 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4273 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4921393 7115208 Mchl_4640 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002423342.1 4920470 D 440085 CDS YP_002423343.1 218532527 7115209 4921390..4922481 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4274 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transporters inner membrane component 4922481 7115209 Mchl_4641 Methylobacterium extorquens CM4 binding-protein-dependent transporters inner membrane component YP_002423343.1 4921390 D 440085 CDS YP_002423344.1 218532528 7115210 complement(4922489..4922806) 1 NC_011757.1 KEGG: mex:Mext_4275 hypothetical protein; hypothetical protein 4922806 7115210 Mchl_4642 Methylobacterium extorquens CM4 hypothetical protein YP_002423344.1 4922489 R 440085 CDS YP_002423345.1 218532529 7115211 4922911..4924389 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: mex:Mext_4276 major facilitator transporter; major facilitator superfamily protein 4924389 7115211 Mchl_4643 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423345.1 4922911 D 440085 CDS YP_002423346.1 218532530 7115212 complement(4924483..4925073) 1 NC_011757.1 KEGG: mex:Mext_4277 hypothetical protein; hypothetical protein 4925073 7115212 Mchl_4644 Methylobacterium extorquens CM4 hypothetical protein YP_002423346.1 4924483 R 440085 CDS YP_002423347.1 218532531 7115213 complement(4925213..4925911) 1 NC_011757.1 PFAM: protein of unknown function DUF1013; KEGG: mex:Mext_4278 hypothetical protein; hypothetical protein 4925911 7115213 Mchl_4645 Methylobacterium extorquens CM4 hypothetical protein YP_002423347.1 4925213 R 440085 CDS YP_002423348.1 218532532 7115214 complement(4926143..4927081) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4279 LysR substrate-binding; LysR family transcriptional regulator 4927081 7115214 Mchl_4646 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423348.1 4926143 R 440085 CDS YP_002423349.1 218532533 7115215 4927282..4927881 1 NC_011757.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 4927881 7115215 Mchl_4647 Methylobacterium extorquens CM4 TrpR binding protein WrbA YP_002423349.1 4927282 D 440085 CDS YP_002423350.1 218532534 7115216 complement(4927943..4930090) 1 NC_011757.1 KEGG: mex:Mext_4281 thiol:disulfide interchange protein; thiol:disulfide interchange protein 4930090 7115216 Mchl_4648 Methylobacterium extorquens CM4 thiol:disulfide interchange protein YP_002423350.1 4927943 R 440085 CDS YP_002423351.1 218532535 7115217 complement(4930283..4933033) 1 NC_011757.1 TIGRFAM: DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS domain protein; MutS III domain protein; MutS II domain protein; MutS IV domain protein; KEGG: mex:Mext_4282 DNA mismatch repair protein MutS; DNA mismatch repair protein MutS 4933033 7115217 Mchl_4649 Methylobacterium extorquens CM4 DNA mismatch repair protein MutS YP_002423351.1 4930283 R 440085 CDS YP_002423352.1 218532536 7115218 complement(4933221..4933538) 1 NC_011757.1 KEGG: mex:Mext_4283 hypothetical protein; hypothetical protein 4933538 7115218 Mchl_4650 Methylobacterium extorquens CM4 hypothetical protein YP_002423352.1 4933221 R 440085 CDS YP_002423353.1 218532537 7115219 4933720..4936221 1 NC_011757.1 KEGG: mex:Mext_4284 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase; helicase-associated domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases; ATP-dependent helicase HrpB 4936221 7115219 Mchl_4651 Methylobacterium extorquens CM4 ATP-dependent helicase HrpB YP_002423353.1 4933720 D 440085 CDS YP_002423354.1 218532538 7115220 complement(4936178..4936903) 1 NC_011757.1 KEGG: mex:Mext_4285 hypothetical protein; hypothetical protein 4936903 7115220 Mchl_4652 Methylobacterium extorquens CM4 hypothetical protein YP_002423354.1 4936178 R 440085 CDS YP_002423355.1 218532539 7115221 4937104..4937475 1 NC_011757.1 KEGG: mex:Mext_4286 hypothetical protein; hypothetical protein 4937475 7115221 Mchl_4653 Methylobacterium extorquens CM4 hypothetical protein YP_002423355.1 4937104 D 440085 CDS YP_002423356.1 218532540 7115222 complement(4937490..4937885) 1 NC_011757.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_4287 glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 4937885 7115222 Mchl_4654 Methylobacterium extorquens CM4 glyoxalase/bleomycin resistance protein/dioxygenase YP_002423356.1 4937490 R 440085 CDS YP_002423357.1 218532541 7115223 4938008..4939105 1 NC_011757.1 TIGRFAM: tyrosine recombinase XerC; PFAM: integrase family protein; integrase; KEGG: mex:Mext_4288 tyrosine recombinase XerC; tyrosine recombinase XerC 4939105 7115223 Mchl_4655 Methylobacterium extorquens CM4 tyrosine recombinase XerC YP_002423357.1 4938008 D 440085 CDS YP_002423358.1 218532542 7115224 4939205..4939339 1 NC_011757.1 KEGG: mpo:Mpop_4806 hypothetical protein; hypothetical protein 4939339 7115224 Mchl_4656 Methylobacterium extorquens CM4 hypothetical protein YP_002423358.1 4939205 D 440085 CDS YP_002423359.1 218532543 7115225 complement(4939421..4940017) 1 NC_011757.1 PFAM: phosphoglycerate mutase; KEGG: mex:Mext_4289 phosphoglycerate mutase; phosphoglycerate mutase 4940017 7115225 Mchl_4657 Methylobacterium extorquens CM4 phosphoglycerate mutase YP_002423359.1 4939421 R 440085 CDS YP_002423360.1 218532544 7115226 4940193..4941197 1 NC_011757.1 PFAM: protein of unknown function DUF344; KEGG: mex:Mext_4290 hypothetical protein; hypothetical protein 4941197 7115226 Mchl_4658 Methylobacterium extorquens CM4 hypothetical protein YP_002423360.1 4940193 D 440085 CDS YP_002423361.1 218532545 7115227 4941287..4942444 1 NC_011757.1 KEGG: mrd:Mrad2831_5526 hypothetical protein; hypothetical protein 4942444 7115227 Mchl_4659 Methylobacterium extorquens CM4 hypothetical protein YP_002423361.1 4941287 D 440085 CDS YP_002423362.1 218532546 7115228 4942446..4943108 1 NC_011757.1 PFAM: MOSC domain containing protein; KEGG: mex:Mext_4291 MOSC domain-containing protein; MOSC domain-containing protein 4943108 7115228 Mchl_4660 Methylobacterium extorquens CM4 MOSC domain-containing protein YP_002423362.1 4942446 D 440085 CDS YP_002423363.1 218532547 7115229 complement(4943139..4943966) 1 NC_011757.1 KEGG: mex:Mext_4292 enoyl-acyl carrier protein reductase; enoyl-acyl carrier protein reductase 4943966 7115229 Mchl_4661 Methylobacterium extorquens CM4 enoyl-acyl carrier protein reductase YP_002423363.1 4943139 R 440085 CDS YP_002423364.1 218532548 7115230 complement(4944211..4945161) 1 NC_011757.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: mex:Mext_4293 heat shock protein DnaJ domain-containing protein; heat shock protein DnaJ domain-containing protein 4945161 7115230 Mchl_4662 Methylobacterium extorquens CM4 heat shock protein DnaJ domain-containing protein YP_002423364.1 4944211 R 440085 CDS YP_002423365.1 218532549 7115231 complement(4945307..4945849) 1 NC_011757.1 KEGG: mex:Mext_4294 hypothetical protein; hypothetical protein 4945849 7115231 Mchl_4663 Methylobacterium extorquens CM4 hypothetical protein YP_002423365.1 4945307 R 440085 CDS YP_002423366.1 218532550 7115232 4945935..4946579 1 NC_011757.1 KEGG: mex:Mext_4295 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase 4946579 7115232 Mchl_4664 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase YP_002423366.1 4945935 D 440085 CDS YP_002423367.1 218532551 7115233 complement(4946628..4947011) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4296 response regulator receiver; response regulator receiver protein 4947011 7115233 Mchl_4665 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423367.1 4946628 R 440085 CDS YP_002423368.1 218532552 7115234 4947295..4948047 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_4297 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 4948047 7115234 Mchl_4666 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423368.1 4947295 D 440085 CDS YP_002423369.1 218532553 7115235 4948040..4949185 1 NC_011757.1 KEGG: mex:Mext_4298 hypothetical protein; hypothetical protein 4949185 7115235 Mchl_4667 Methylobacterium extorquens CM4 hypothetical protein YP_002423369.1 4948040 D 440085 CDS YP_002423370.1 218532554 7115236 4949182..4949667 1 NC_011757.1 PFAM: NUDIX hydrolase; KEGG: mex:Mext_4299 NUDIX hydrolase; NUDIX hydrolase 4949667 7115236 Mchl_4668 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002423370.1 4949182 D 440085 CDS YP_002423371.1 218532555 7115237 4949664..4950113 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_4300 hypothetical protein; hypothetical protein 4950113 7115237 Mchl_4669 Methylobacterium extorquens CM4 hypothetical protein YP_002423371.1 4949664 D 440085 CDS YP_002423372.1 218532556 7115238 4950451..4950705 1 NC_011757.1 KEGG: mex:Mext_4301 hypothetical protein; hypothetical protein 4950705 7115238 Mchl_4670 Methylobacterium extorquens CM4 hypothetical protein YP_002423372.1 4950451 D 440085 CDS YP_002423373.1 218532557 7115239 complement(4950904..4952460) 1 NC_011757.1 KEGG: mex:Mext_4302 hypothetical protein; hypothetical protein 4952460 7115239 Mchl_4671 Methylobacterium extorquens CM4 hypothetical protein YP_002423373.1 4950904 R 440085 CDS YP_002423374.1 218532558 7115240 complement(4952761..4954098) 1 NC_011757.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 4954098 7115240 Mchl_4672 Methylobacterium extorquens CM4 dihydroorotase YP_002423374.1 4952761 R 440085 CDS YP_002423375.1 218532559 7115241 4954200..4955054 1 NC_011757.1 TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; KEGG: mex:Mext_4304 folate-binding protein YgfZ; folate-binding protein YgfZ 4955054 7115241 Mchl_4673 Methylobacterium extorquens CM4 folate-binding protein YgfZ YP_002423375.1 4954200 D 440085 CDS YP_002423376.1 218532560 7115242 4955051..4955680 1 NC_011757.1 PFAM: methyladenine glycosylase; KEGG: mex:Mext_4305 DNA-3-methyladenine glycosylase I; DNA-3-methyladenine glycosylase I 4955680 7115242 Mchl_4674 Methylobacterium extorquens CM4 DNA-3-methyladenine glycosylase I YP_002423376.1 4955051 D 440085 CDS YP_002423377.1 218532561 7115243 4955677..4956303 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: mex:Mext_4306 metal-dependent phosphohydrolase; metal dependent phosphohydrolase 4956303 7115243 Mchl_4675 Methylobacterium extorquens CM4 metal dependent phosphohydrolase YP_002423377.1 4955677 D 440085 CDS YP_002423378.1 218532562 7115244 4956318..4956830 1 NC_011757.1 KEGG: mex:Mext_4307 hypothetical protein; hypothetical protein 4956830 7115244 Mchl_4676 Methylobacterium extorquens CM4 hypothetical protein YP_002423378.1 4956318 D 440085 CDS YP_002423379.1 218532563 7115245 4956930..4957196 1 NC_011757.1 TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; KEGG: mex:Mext_4308 exodeoxyribonuclease VII small subunit; exodeoxyribonuclease VII small subunit 4957196 7115245 Mchl_4677 Methylobacterium extorquens CM4 exodeoxyribonuclease VII small subunit YP_002423379.1 4956930 D 440085 CDS YP_002423380.1 218532564 7115246 4957286..4959262 1 NC_011757.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 4959262 7115246 Mchl_4678 Methylobacterium extorquens CM4 1-deoxy-D-xylulose-5-phosphate synthase YP_002423380.1 4957286 D 440085 CDS YP_002423381.1 218532565 7115247 complement(4959308..4959913) 1 NC_011757.1 PFAM: superoxide dismutase copper/zinc binding; KEGG: mex:Mext_4310 superoxide dismutase copper/zinc binding; superoxide dismutase copper/zinc binding 4959913 7115247 Mchl_4679 Methylobacterium extorquens CM4 superoxide dismutase copper/zinc binding YP_002423381.1 4959308 R 440085 CDS YP_002423382.1 218532566 7115248 4960273..4961025 1 NC_011757.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: mex:Mext_4311 hemolysin A; hemolysin A 4961025 7115248 Mchl_4680 Methylobacterium extorquens CM4 hemolysin A YP_002423382.1 4960273 D 440085 CDS YP_002423383.1 218532567 7115249 4961025..4962320 1 NC_011757.1 PFAM: (uracil-5)-methyltransferase; KEGG: mex:Mext_4312 (uracil-5)-methyltransferase; (uracil-5)-methyltransferase 4962320 7115249 Mchl_4681 Methylobacterium extorquens CM4 (uracil-5)-methyltransferase YP_002423383.1 4961025 D 440085 CDS YP_002423384.1 218532568 7115250 complement(4962394..4963638) 1 NC_011757.1 KEGG: mex:Mext_4313 capsular polysaccharide biosynthesis protein-like protein; capsular polysaccharide biosynthesis protein-like protein 4963638 7115250 Mchl_4682 Methylobacterium extorquens CM4 capsular polysaccharide biosynthesis protein-like protein YP_002423384.1 4962394 R 440085 CDS YP_002423385.1 218532569 7115251 4963954..4964949 1 NC_011757.1 KEGG: mex:Mext_4314 hypothetical protein; hypothetical protein 4964949 7115251 Mchl_4683 Methylobacterium extorquens CM4 hypothetical protein YP_002423385.1 4963954 D 440085 CDS YP_002423386.1 218532570 7115252 complement(4964962..4965693) 1 NC_011757.1 PFAM: protein of unknown function DUF159; KEGG: mex:Mext_4315 hypothetical protein; hypothetical protein 4965693 7115252 Mchl_4684 Methylobacterium extorquens CM4 hypothetical protein YP_002423386.1 4964962 R 440085 CDS YP_002423387.1 218532571 7115253 4965862..4967082 1 NC_011757.1 PFAM: protein of unknown function DUF482; KEGG: mex:Mext_4316 hypothetical protein; hypothetical protein 4967082 7115253 Mchl_4685 Methylobacterium extorquens CM4 hypothetical protein YP_002423387.1 4965862 D 440085 CDS YP_002423388.1 218532572 7115254 4967079..4968236 1 NC_011757.1 KEGG: mex:Mext_4317 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; amidohydrolase 4968236 7115254 Mchl_4686 Methylobacterium extorquens CM4 amidohydrolase YP_002423388.1 4967079 D 440085 CDS YP_002423389.1 218532573 7115255 4968487..4969572 1 NC_011757.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: mex:Mext_4318 methylated-DNA--protein-cysteine methyltransferase; AraC family transcriptional regulator 4969572 7115255 Mchl_4687 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002423389.1 4968487 D 440085 CDS YP_002423390.1 218532574 7115256 complement(4969577..4970599) 1 NC_011757.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mex:Mext_4319 cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 4970599 7115256 Mchl_4688 Methylobacterium extorquens CM4 cation diffusion facilitator family transporter YP_002423390.1 4969577 R 440085 CDS YP_002423391.1 218532575 7115257 4970721..4971149 1 NC_011757.1 PFAM: histidine triad (HIT) protein; KEGG: mex:Mext_4320 histidine triad (HIT) protein; histidine triad (HIT) protein 4971149 7115257 Mchl_4689 Methylobacterium extorquens CM4 histidine triad (HIT) protein YP_002423391.1 4970721 D 440085 CDS YP_002423392.1 218532576 7115258 complement(4971206..4971652) 1 NC_011757.1 PFAM: type IV pilus assembly PilZ; KEGG: mex:Mext_4321 type IV pilus assembly PilZ; type IV pilus assembly PilZ 4971652 7115258 Mchl_4690 Methylobacterium extorquens CM4 type IV pilus assembly PilZ YP_002423392.1 4971206 R 440085 CDS YP_002423393.1 218532577 7115259 complement(4971734..4971982) 1 NC_011757.1 KEGG: mex:Mext_4322 hypothetical protein; hypothetical protein 4971982 7115259 Mchl_4691 Methylobacterium extorquens CM4 hypothetical protein YP_002423393.1 4971734 R 440085 CDS YP_002423394.1 218532578 7115260 complement(4972248..4974131) 1 NC_011757.1 PFAM: glycoside hydrolase 15-related; KEGG: mex:Mext_4323 glycoside hydrolase 15-related; glycoside hydrolase 15-like protein 4974131 7115260 Mchl_4692 Methylobacterium extorquens CM4 glycoside hydrolase 15-like protein YP_002423394.1 4972248 R 440085 CDS YP_002423395.1 218532579 7115261 complement(4974223..4974501) 1 NC_011757.1 KEGG: mex:Mext_4324 hypothetical protein; hypothetical protein 4974501 7115261 Mchl_4693 Methylobacterium extorquens CM4 hypothetical protein YP_002423395.1 4974223 R 440085 CDS YP_002423396.1 218532580 7115262 complement(4974564..4975730) 1 NC_011757.1 KEGG: mex:Mext_4325 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 4975730 7115262 Mchl_4694 Methylobacterium extorquens CM4 N-acetylglucosamine-6-phosphate deacetylase YP_002423396.1 4974564 R 440085 CDS YP_002423397.1 218532581 7115263 complement(4975828..4976838) 1 NC_011757.1 PFAM: sugar isomerase (SIS); KEGG: mex:Mext_4326 glutamine--fructose-6-phosphate transaminase (isomerizing); glutamine--fructose-6-phosphate transaminase 4976838 7115263 Mchl_4695 Methylobacterium extorquens CM4 glutamine--fructose-6-phosphate transaminase YP_002423397.1 4975828 R 440085 CDS YP_002423398.1 218532582 7115264 complement(4976835..4977722) 1 NC_011757.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 4977722 murQ 7115264 murQ Methylobacterium extorquens CM4 N-acetylmuramic acid-6-phosphate etherase YP_002423398.1 4976835 R 440085 CDS YP_002423399.1 218532583 7115265 4977817..4978803 1 NC_011757.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: mex:Mext_4328 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 4978803 7115265 Mchl_4697 Methylobacterium extorquens CM4 endonuclease/exonuclease/phosphatase YP_002423399.1 4977817 D 440085 CDS YP_002423400.1 218532584 7118015 4978882..4979949 1 NC_011757.1 PFAM: asparaginase/glutaminase; KEGG: mex:Mext_4329 asparaginase; asparaginase 4979949 7118015 Mchl_4698 Methylobacterium extorquens CM4 asparaginase YP_002423400.1 4978882 D 440085 CDS YP_002423401.1 218532585 7118064 complement(4980066..4981607) 1 NC_011757.1 PFAM: phospholipase D/transphosphatidylase; KEGG: mex:Mext_4330 phospholipase D/transphosphatidylase; phospholipase D/transphosphatidylase 4981607 7118064 Mchl_4699 Methylobacterium extorquens CM4 phospholipase D/transphosphatidylase YP_002423401.1 4980066 R 440085 CDS YP_002423402.1 218532586 7118065 complement(4981672..4982370) 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_4331 hypothetical protein; hypothetical protein 4982370 7118065 Mchl_4700 Methylobacterium extorquens CM4 hypothetical protein YP_002423402.1 4981672 R 440085 CDS YP_002423403.1 218532587 7118066 complement(4982516..4982926) 1 NC_011757.1 KEGG: mex:Mext_4332 hypothetical protein; hypothetical protein 4982926 7118066 Mchl_4701 Methylobacterium extorquens CM4 hypothetical protein YP_002423403.1 4982516 R 440085 CDS YP_002423404.1 218532588 7118067 complement(4983142..4983831) 1 NC_011757.1 PFAM: Surfeit locus 1 family protein; KEGG: mex:Mext_4333 surfeit locus 1 family protein; Surfeit locus 1 family protein 4983831 7118067 Mchl_4702 Methylobacterium extorquens CM4 Surfeit locus 1 family protein YP_002423404.1 4983142 R 440085 CDS YP_002423405.1 218532589 7118068 complement(4983929..4984309) 1 NC_011757.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: mex:Mext_4334 cytochrome o ubiquinol oxidase subunit IV; cytochrome o ubiquinol oxidase subunit IV 4984309 7118068 Mchl_4703 Methylobacterium extorquens CM4 cytochrome o ubiquinol oxidase subunit IV YP_002423405.1 4983929 R 440085 CDS YP_002423406.1 218532590 7118069 complement(4984306..4984953) 1 NC_011757.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome C oxidase subunit III; KEGG: mex:Mext_4335 cytochrome o ubiquinol oxidase subunit III; cytochrome o ubiquinol oxidase subunit III 4984953 7118069 Mchl_4704 Methylobacterium extorquens CM4 cytochrome o ubiquinol oxidase subunit III YP_002423406.1 4984306 R 440085 CDS YP_002423407.1 218532591 7118070 complement(4984962..4986965) 1 NC_011757.1 KEGG: mex:Mext_4336 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome c oxidase subunit I; cytochrome o ubiquinol oxidase subunit I 4986965 7118070 Mchl_4705 Methylobacterium extorquens CM4 cytochrome o ubiquinol oxidase subunit I YP_002423407.1 4984962 R 440085 CDS YP_002423408.1 218532592 7118071 complement(4987005..4988168) 1 NC_011757.1 TIGRFAM: ubiquinol oxidase subunit II; PFAM: cytochrome C oxidase subunit II; COX aromatic rich domain protein; KEGG: mex:Mext_4337 ubiquinol oxidase subunit II; ubiquinol oxidase subunit II 4988168 7118071 Mchl_4706 Methylobacterium extorquens CM4 ubiquinol oxidase subunit II YP_002423408.1 4987005 R 440085 CDS YP_002423409.1 218532593 7118072 complement(4988363..4989697) 1 NC_011757.1 KEGG: mex:Mext_4338 ABC transporter transmembrane protein; ABC transporter transmembrane protein 4989697 7118072 Mchl_4707 Methylobacterium extorquens CM4 ABC transporter transmembrane protein YP_002423409.1 4988363 R 440085 CDS YP_002423410.1 218532594 7118073 complement(4989989..4993051) 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_4339 acriflavin resistance protein; acriflavin resistance protein 4993051 7118073 Mchl_4708 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002423410.1 4989989 R 440085 CDS YP_002423411.1 218532595 7118074 complement(4993120..4994271) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_4340 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4994271 7118074 Mchl_4709 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002423411.1 4993120 R 440085 CDS YP_002423412.1 218532596 7118075 complement(4994268..4995419) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_4341 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 4995419 7118075 Mchl_4710 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002423412.1 4994268 R 440085 CDS YP_002423413.1 218532597 7118076 4995639..4996199 1 NC_011757.1 PFAM: regulatory protein TetR; KEGG: mex:Mext_4342 regulatory protein TetR; TetR family transcriptional regulator 4996199 7118076 Mchl_4711 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002423413.1 4995639 D 440085 CDS YP_002423414.1 218532598 7118077 complement(4996519..4997229) 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_4343 response regulator receiver; LuxR family transcriptional regulator 4997229 7118077 Mchl_4712 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423414.1 4996519 R 440085 CDS YP_002423415.1 218532599 7118078 complement(4997231..4998445) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mex:Mext_4344 ATPase domain-containing protein; histidine kinase 4998445 7118078 Mchl_4713 Methylobacterium extorquens CM4 histidine kinase YP_002423415.1 4997231 R 440085 CDS YP_002423416.1 218532600 7118079 4999139..4999789 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_4345 regulatory protein LuxR; LuxR family transcriptional regulator 4999789 7118079 Mchl_4714 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423416.1 4999139 D 440085 CDS YP_002423417.1 218532601 7118080 4999983..5000744 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_4346 regulatory protein LuxR; LuxR family transcriptional regulator 5000744 7118080 Mchl_4715 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423417.1 4999983 D 440085 CDS YP_002423418.1 218532602 7118081 5000839..5001657 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: mex:Mext_4347 glycosyl transferase; family 2 glycosyl transferase 5001657 7118081 Mchl_4716 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423418.1 5000839 D 440085 CDS YP_002423419.1 218532603 7118082 5001827..5003011 1 NC_011757.1 KEGG: mex:Mext_4348 hypothetical protein; hypothetical protein 5003011 7118082 Mchl_4717 Methylobacterium extorquens CM4 hypothetical protein YP_002423419.1 5001827 D 440085 CDS YP_002423420.1 218532604 7118084 5003425..5005233 1 NC_011757.1 PFAM: integrase family protein; KEGG: mag:amb4434 integrase; integrase family protein 5005233 7118084 Mchl_4718 Methylobacterium extorquens CM4 integrase family protein YP_002423420.1 5003425 D 440085 CDS YP_002423421.1 218532605 7118085 complement(5005422..5005682) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: bja:bsr0038 transcriptional regulator; XRE family transcriptional regulator 5005682 7118085 Mchl_4719 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002423421.1 5005422 R 440085 CDS YP_002423422.1 218532606 7118086 5005790..5007040 1 NC_011757.1 PFAM: beta-lactamase; KEGG: dvl:Dvul_0859 beta-lactamase domain-containing protein; beta-lactamase 5007040 7118086 Mchl_4720 Methylobacterium extorquens CM4 beta-lactamase YP_002423422.1 5005790 D 440085 CDS YP_002423423.1 218532607 7118087 5007019..5008116 1 NC_011757.1 KEGG: bja:bll0880 hypothetical protein; hypothetical protein 5008116 7118087 Mchl_4721 Methylobacterium extorquens CM4 hypothetical protein YP_002423423.1 5007019 D 440085 CDS YP_002423424.1 218532608 7118088 5008425..5009255 1 NC_011757.1 hypothetical protein 5009255 7118088 Mchl_4722 Methylobacterium extorquens CM4 hypothetical protein YP_002423424.1 5008425 D 440085 CDS YP_002423425.1 218532609 7118089 5009283..5009720 1 NC_011757.1 KEGG: sus:acid_0788 hypothetical protein; hypothetical protein 5009720 7118089 Mchl_4723 Methylobacterium extorquens CM4 hypothetical protein YP_002423425.1 5009283 D 440085 CDS YP_002423426.1 218532610 7118090 5009738..5010439 1 NC_011757.1 hypothetical protein 5010439 7118090 Mchl_4724 Methylobacterium extorquens CM4 hypothetical protein YP_002423426.1 5009738 D 440085 CDS YP_002423427.1 218532611 7118091 complement(5010541..5010684) 1 NC_011757.1 hypothetical protein 5010684 7118091 Mchl_4725 Methylobacterium extorquens CM4 hypothetical protein YP_002423427.1 5010541 R 440085 CDS YP_002423428.1 218532612 7118092 complement(5010840..5011826) 1 NC_011757.1 KEGG: shn:Shewana3_2964 hypothetical protein; hypothetical protein 5011826 7118092 Mchl_4726 Methylobacterium extorquens CM4 hypothetical protein YP_002423428.1 5010840 R 440085 CDS YP_002423429.1 218532613 7118093 5012365..5012631 1 NC_011757.1 PFAM: protein of unknown function DUF156; KEGG: mpo:Mpop_1883 protein of unknown function DUF156; hypothetical protein 5012631 7118093 Mchl_4727 Methylobacterium extorquens CM4 hypothetical protein YP_002423429.1 5012365 D 440085 CDS YP_002423430.1 218532614 7118094 5012639..5013973 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mpo:Mpop_1884 major facilitator superfamily MFS_1; major facilitator superfamily protein 5013973 7118094 Mchl_4728 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423430.1 5012639 D 440085 CDS YP_002423431.1 218532615 7118095 5014098..5014532 1 NC_011757.1 KEGG: mpo:Mpop_1885 DNA polymerase III subunits gamma and tau; DNA polymerase III subunits gamma and tau 5014532 7118095 Mchl_4729 Methylobacterium extorquens CM4 DNA polymerase III subunits gamma and tau YP_002423431.1 5014098 D 440085 CDS YP_002423432.1 218532616 7118096 5014589..5016316 1 NC_011757.1 KEGG: mpo:Mpop_1886 efflux transporter RND family, MFP subunit; efflux transporter RND family MFP subunit 5016316 7118096 Mchl_4730 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002423432.1 5014589 D 440085 CDS YP_002423433.1 218532617 7118097 5016325..5019438 1 NC_011757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mpo:Mpop_1887 heavy metal efflux pump, CzcA family; CzcA family heavy metal efflux pump 5019438 7118097 Mchl_4731 Methylobacterium extorquens CM4 CzcA family heavy metal efflux pump YP_002423433.1 5016325 D 440085 CDS YP_002423434.1 218532618 7118098 5019456..5019833 1 NC_011757.1 KEGG: mpo:Mpop_1888 hypothetical protein; hypothetical protein 5019833 7118098 Mchl_4732 Methylobacterium extorquens CM4 hypothetical protein YP_002423434.1 5019456 D 440085 CDS YP_002423435.1 218532619 7118099 5019969..5020184 1 NC_011757.1 KEGG: nha:Nham_3588 hypothetical protein; hypothetical protein 5020184 7118099 Mchl_4733 Methylobacterium extorquens CM4 hypothetical protein YP_002423435.1 5019969 D 440085 CDS YP_002423436.1 218532620 7118100 complement(5020283..5020945) 1 NC_011757.1 KEGG: mex:Mext_1125 hypothetical protein; hypothetical protein 5020945 7118100 Mchl_4734 Methylobacterium extorquens CM4 hypothetical protein YP_002423436.1 5020283 R 440085 CDS YP_002423437.1 218532621 7118101 5021247..5022077 1 NC_011757.1 SMART: rhodanese; KEGG: mpo:Mpop_1890 rhodanese domain protein; rhodanese 5022077 7118101 Mchl_4735 Methylobacterium extorquens CM4 rhodanese YP_002423437.1 5021247 D 440085 CDS YP_002423438.1 218532622 7118102 5022074..5023489 1 NC_011757.1 TIGRFAM: chromate transporter chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: mex:Mext_1475 chromate transporter; chromate ion transporter (CHR) family chromate transporter 5023489 7118102 Mchl_4736 Methylobacterium extorquens CM4 chromate ion transporter (CHR) family chromate transporter YP_002423438.1 5022074 D 440085 CDS YP_002423439.1 218532623 7118103 5023489..5024133 1 NC_011757.1 KEGG: mpo:Mpop_1892 hypothetical protein; hypothetical protein 5024133 7118103 Mchl_4737 Methylobacterium extorquens CM4 hypothetical protein YP_002423439.1 5023489 D 440085 CDS YP_002423440.1 218532624 7118104 5024130..5024522 1 NC_011757.1 KEGG: mpo:Mpop_1893 hypothetical protein; hypothetical protein 5024522 7118104 Mchl_4738 Methylobacterium extorquens CM4 hypothetical protein YP_002423440.1 5024130 D 440085 CDS YP_002423441.1 218532625 7118105 5024564..5025526 1 NC_011757.1 PFAM: protein of unknown function LppY and LpqO; KEGG: mpo:Mpop_1894 protein of unknown function LppY and LpqO; hypothetical protein 5025526 7118105 Mchl_4739 Methylobacterium extorquens CM4 hypothetical protein YP_002423441.1 5024564 D 440085 CDS YP_002423442.1 218532626 7118106 5025532..5026578 1 NC_011757.1 KEGG: mpo:Mpop_1895 hypothetical protein; hypothetical protein 5026578 7118106 Mchl_4740 Methylobacterium extorquens CM4 hypothetical protein YP_002423442.1 5025532 D 440085 CDS YP_002423443.1 218532627 7118107 5026630..5026911 1 NC_011757.1 hypothetical protein 5026911 7118107 Mchl_4741 Methylobacterium extorquens CM4 hypothetical protein YP_002423443.1 5026630 D 440085 CDS YP_002423444.1 218532628 7118108 5027468..5028682 1 NC_011757.1 KEGG: met:M446_1502 hypothetical protein; hypothetical protein 5028682 7118108 Mchl_4742 Methylobacterium extorquens CM4 hypothetical protein YP_002423444.1 5027468 D 440085 CDS YP_002423445.1 218532629 7118109 5029129..5029629 1 NC_011757.1 hypothetical protein 5029629 7118109 Mchl_4743 Methylobacterium extorquens CM4 hypothetical protein YP_002423445.1 5029129 D 440085 CDS YP_002423446.1 218532630 7118110 5029905..5035538 1 NC_011757.1 KEGG: rec:RHECIAT_CH0003310 superfamily I DNA and RNA helicase protein; superfamily I DNA and RNA helicase protein 5035538 7118110 Mchl_4744 Methylobacterium extorquens CM4 superfamily I DNA and RNA helicase protein YP_002423446.1 5029905 D 440085 CDS YP_002423447.1 218532631 7118111 5035682..5036275 1 NC_011757.1 hypothetical protein 5036275 7118111 Mchl_4745 Methylobacterium extorquens CM4 hypothetical protein YP_002423447.1 5035682 D 440085 CDS YP_002423448.1 218532632 7118112 complement(5036968..5037822) 1 NC_011757.1 hypothetical protein 5037822 7118112 Mchl_4746 Methylobacterium extorquens CM4 hypothetical protein YP_002423448.1 5036968 R 440085 CDS YP_002423449.1 218532633 7118113 complement(5037960..5038250) 1 NC_011757.1 hypothetical protein 5038250 7118113 Mchl_4747 Methylobacterium extorquens CM4 hypothetical protein YP_002423449.1 5037960 R 440085 CDS YP_002423450.1 218532634 7118114 complement(5038607..5039395) 1 NC_011757.1 hypothetical protein 5039395 7118114 Mchl_4748 Methylobacterium extorquens CM4 hypothetical protein YP_002423450.1 5038607 R 440085 CDS YP_002423451.1 218532635 7118115 5039549..5040532 1 NC_011757.1 PFAM: domain of unknown function DUF1738; KEGG: mex:Mext_3581 hypothetical protein; hypothetical protein 5040532 7118115 Mchl_4749 Methylobacterium extorquens CM4 hypothetical protein YP_002423451.1 5039549 D 440085 CDS YP_002423452.1 218532636 7118116 5040529..5041134 1 NC_011757.1 hypothetical protein 5041134 7118116 Mchl_4750 Methylobacterium extorquens CM4 hypothetical protein YP_002423452.1 5040529 D 440085 CDS YP_002423453.1 218532637 7118117 5041675..5042685 1 NC_011757.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_4349 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 5042685 7118117 Mchl_4751 Methylobacterium extorquens CM4 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_002423453.1 5041675 D 440085 CDS YP_002423454.1 218532638 7118118 complement(5042714..5043667) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4350 LysR substrate-binding; LysR family transcriptional regulator 5043667 7118118 Mchl_4752 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423454.1 5042714 R 440085 CDS YP_002423455.1 218532639 7118119 5043841..5044089 1 NC_011757.1 KEGG: mex:Mext_4351 hypothetical protein; hypothetical protein 5044089 7118119 Mchl_4753 Methylobacterium extorquens CM4 hypothetical protein YP_002423455.1 5043841 D 440085 CDS YP_002423456.1 218532640 7118120 5044143..5044895 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_4352 hypothetical protein; hypothetical protein 5044895 7118120 Mchl_4754 Methylobacterium extorquens CM4 hypothetical protein YP_002423456.1 5044143 D 440085 CDS YP_002423457.1 218532641 7118121 complement(5044965..5045861) 1 NC_011757.1 KEGG: mex:Mext_4353 hypothetical protein; hypothetical protein 5045861 7118121 Mchl_4755 Methylobacterium extorquens CM4 hypothetical protein YP_002423457.1 5044965 R 440085 CDS YP_002423458.1 218532642 7118122 complement(5045873..5046847) 1 NC_011757.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_4354 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 5046847 7118122 Mchl_4756 Methylobacterium extorquens CM4 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_002423458.1 5045873 R 440085 CDS YP_002423459.1 218532643 7118123 5047122..5048531 1 NC_011757.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 5048531 7118123 Mchl_4757 Methylobacterium extorquens CM4 isopropylmalate isomerase large subunit YP_002423459.1 5047122 D 440085 CDS YP_002423460.1 218532644 7118125 complement(5048714..5049931) 1 NC_011757.1 PFAM: integrase family protein; KEGG: dsh:Dshi_0988 integrase family protein; integrase family protein 5049931 7118125 Mchl_4758 Methylobacterium extorquens CM4 integrase family protein YP_002423460.1 5048714 R 440085 CDS YP_002423461.1 218532645 7118126 complement(5049946..5050230) 1 NC_011757.1 KEGG: jan:Jann_2864 hypothetical protein; hypothetical protein 5050230 7118126 Mchl_4759 Methylobacterium extorquens CM4 hypothetical protein YP_002423461.1 5049946 R 440085 CDS YP_002423462.1 218532646 7118127 5051408..5051839 1 NC_011757.1 hypothetical protein 5051839 7118127 Mchl_4760 Methylobacterium extorquens CM4 hypothetical protein YP_002423462.1 5051408 D 440085 CDS YP_002423463.1 218532647 7118128 5051903..5052166 1 NC_011757.1 hypothetical protein 5052166 7118128 Mchl_4761 Methylobacterium extorquens CM4 hypothetical protein YP_002423463.1 5051903 D 440085 CDS YP_002423464.1 218532648 7118129 5052910..5054010 1 NC_011757.1 KEGG: rsq:Rsph17025_4201 hypothetical protein; hypothetical protein 5054010 7118129 Mchl_4762 Methylobacterium extorquens CM4 hypothetical protein YP_002423464.1 5052910 D 440085 CDS YP_002423465.1 218532649 7118130 5054010..5054240 1 NC_011757.1 KEGG: bvi:Bcep1808_6235 hypothetical protein; hypothetical protein 5054240 7118130 Mchl_4763 Methylobacterium extorquens CM4 hypothetical protein YP_002423465.1 5054010 D 440085 CDS YP_002423466.1 218532650 7118131 5054237..5054719 1 NC_011757.1 KEGG: similar to DnaJ (Hsp40) homolog, subfamily B; hypothetical protein 5054719 7118131 Mchl_4764 Methylobacterium extorquens CM4 hypothetical protein YP_002423466.1 5054237 D 440085 CDS YP_002423467.1 218532651 7118132 5054716..5054844 1 NC_011757.1 hypothetical protein 5054844 7118132 Mchl_4765 Methylobacterium extorquens CM4 hypothetical protein YP_002423467.1 5054716 D 440085 CDS YP_002423468.1 218532652 7118133 complement(5054953..5056176) 1 NC_011757.1 KEGG: ckl:CKL_3898 hypothetical protein; hypothetical protein 5056176 7118133 Mchl_4766 Methylobacterium extorquens CM4 hypothetical protein YP_002423468.1 5054953 R 440085 CDS YP_002423469.1 218532653 7118134 complement(5056301..5056510) 1 NC_011757.1 hypothetical protein 5056510 7118134 Mchl_4767 Methylobacterium extorquens CM4 hypothetical protein YP_002423469.1 5056301 R 440085 CDS YP_002423470.1 218532654 7118135 5056931..5057164 1 NC_011757.1 hypothetical protein 5057164 7118135 Mchl_4768 Methylobacterium extorquens CM4 hypothetical protein YP_002423470.1 5056931 D 440085 CDS YP_002423471.1 218532655 7118136 5057276..5057791 1 NC_011757.1 hypothetical protein 5057791 7118136 Mchl_4769 Methylobacterium extorquens CM4 hypothetical protein YP_002423471.1 5057276 D 440085 CDS YP_002423472.1 218532656 7118137 5057999..5058418 1 NC_011757.1 hypothetical protein 5058418 7118137 Mchl_4770 Methylobacterium extorquens CM4 hypothetical protein YP_002423472.1 5057999 D 440085 CDS YP_002423473.1 218532657 7118138 5058651..5058899 1 NC_011757.1 KEGG: mex:Mext_4519 hypothetical protein; hypothetical protein 5058899 7118138 Mchl_4771 Methylobacterium extorquens CM4 hypothetical protein YP_002423473.1 5058651 D 440085 CDS YP_002423474.1 218532658 7118139 5059448..5060377 1 NC_011757.1 PFAM: intradiol ring-cleavage dioxygenase; KEGG: bbt:BBta_7382 intradiol ring-cleavage dioxygenase; intradiol ring-cleavage dioxygenase 5060377 7118139 Mchl_4772 Methylobacterium extorquens CM4 intradiol ring-cleavage dioxygenase YP_002423474.1 5059448 D 440085 CDS YP_002423475.1 218532659 7118140 5060579..5061253 1 NC_011757.1 KEGG: mrd:Mrad2831_4030 hypothetical protein; hypothetical protein 5061253 7118140 Mchl_4773 Methylobacterium extorquens CM4 hypothetical protein YP_002423475.1 5060579 D 440085 CDS YP_002423476.1 218532660 7118141 complement(5061475..5062140) 1 NC_011757.1 KEGG: met:M446_4499 hypothetical protein; hypothetical protein 5062140 7118141 Mchl_4774 Methylobacterium extorquens CM4 hypothetical protein YP_002423476.1 5061475 R 440085 CDS YP_002423477.1 218532661 7118142 5062369..5063031 1 NC_011757.1 PFAM: adenylylsulfate kinase; KEGG: mrd:Mrad2831_1882 adenylyl-sulfate kinase; adenylyl-sulfate kinase 5063031 7118142 Mchl_4775 Methylobacterium extorquens CM4 adenylyl-sulfate kinase YP_002423477.1 5062369 D 440085 CDS YP_002423478.1 218532662 7118143 complement(5063205..5063933) 1 NC_011757.1 KEGG: mrd:Mrad2831_1350 GDSL family lipase; GDSL family lipase 5063933 7118143 Mchl_4776 Methylobacterium extorquens CM4 GDSL family lipase YP_002423478.1 5063205 R 440085 CDS YP_002423479.1 218532663 7118144 complement(5064229..5064960) 1 NC_011757.1 PFAM: porin; KEGG: mpo:Mpop_0836 porin; porin 5064960 7118144 Mchl_4777 Methylobacterium extorquens CM4 porin YP_002423479.1 5064229 R 440085 CDS YP_002423480.1 218532664 7118013 complement(5064990..5065154) 1 NC_011757.1 KEGG: mpo:Mpop_0837 hypothetical protein; hypothetical protein 5065154 7118013 Mchl_4778 Methylobacterium extorquens CM4 hypothetical protein YP_002423480.1 5064990 R 440085 CDS YP_002423481.1 218532665 7118229 complement(5065151..5065420) 1 NC_011757.1 hypothetical protein 5065420 7118229 Mchl_4779 Methylobacterium extorquens CM4 hypothetical protein YP_002423481.1 5065151 R 440085 CDS YP_002423482.1 218532666 7118230 5065587..5066462 1 NC_011757.1 KEGG: mpo:Mpop_0839 hypothetical protein; hypothetical protein 5066462 7118230 Mchl_4780 Methylobacterium extorquens CM4 hypothetical protein YP_002423482.1 5065587 D 440085 CDS YP_002423483.1 218532667 7118231 5066459..5067775 1 NC_011757.1 KEGG: mpo:Mpop_0840 hypothetical protein; hypothetical protein 5067775 7118231 Mchl_4781 Methylobacterium extorquens CM4 hypothetical protein YP_002423483.1 5066459 D 440085 CDS YP_002423484.1 218532668 7118232 complement(5067778..5068617) 1 NC_011757.1 KEGG: acr:Acry_2758 hypothetical protein; hypothetical protein 5068617 7118232 Mchl_4782 Methylobacterium extorquens CM4 hypothetical protein YP_002423484.1 5067778 R 440085 CDS YP_002423485.1 218532669 7118233 complement(5068727..5071261) 1 NC_011757.1 TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: mex:Mext_2081 outer membrane protein assembly complex, YaeT protein; outer membrane protein assembly complex, YaeT protein 5071261 7118233 Mchl_4783 Methylobacterium extorquens CM4 outer membrane protein assembly complex, YaeT protein YP_002423485.1 5068727 R 440085 CDS YP_002423486.1 218532670 7118234 5072656..5073096 1 NC_011757.1 KEGG: mpo:Mpop_0721 peptidase C14 caspase catalytic subunit P20; peptidase C14 caspase catalytic subunit P20 5073096 7118234 Mchl_4784 Methylobacterium extorquens CM4 peptidase C14 caspase catalytic subunit P20 YP_002423486.1 5072656 D 440085 CDS YP_002423487.1 218532671 7118235 complement(5073218..5073694) 1 NC_011757.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; KEGG: mex:Mext_0113 PAS sensor protein; PAS sensor protein 5073694 7118235 Mchl_4785 Methylobacterium extorquens CM4 PAS sensor protein YP_002423487.1 5073218 R 440085 CDS YP_002423488.1 218532672 7118236 5073916..5074368 1 NC_011757.1 PFAM: BLUF domain protein; KEGG: mex:Mext_0114 BLUF domain-containing protein; BLUF domain-containing protein 5074368 7118236 Mchl_4786 Methylobacterium extorquens CM4 BLUF domain-containing protein YP_002423488.1 5073916 D 440085 CDS YP_002423489.1 218532673 7118238 complement(5074765..5076822) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: met:M446_1292 integral membrane sensor hybrid histidine kinase; histidine kinase 5076822 7118238 Mchl_4788 Methylobacterium extorquens CM4 histidine kinase YP_002423489.1 5074765 R 440085 CDS YP_002423490.1 218532674 7118239 complement(5077244..5079631) 1 NC_011757.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: mpo:Mpop_0141 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase 5079631 7118239 Mchl_4789 Methylobacterium extorquens CM4 PAS/PAC and MHYT sensor-containing diguanylate cyclase/phosphodiesterase YP_002423490.1 5077244 R 440085 CDS YP_002423491.1 218532675 7118240 complement(5079944..5080573) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_0119 integrase family protein; integrase family protein 5080573 7118240 Mchl_4790 Methylobacterium extorquens CM4 integrase family protein YP_002423491.1 5079944 R 440085 CDS YP_002423492.1 218532676 7118241 complement(5080921..5082612) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: met:M446_6605 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5082612 7118241 Mchl_4791 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423492.1 5080921 R 440085 CDS YP_002423493.1 218532677 7118243 complement(5084312..5085625) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_0121 major facilitator transporter; major facilitator superfamily protein 5085625 7118243 Mchl_4793 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423493.1 5084312 R 440085 CDS YP_002423494.1 218532678 7118244 complement(5085872..5086162) 1 NC_011757.1 KEGG: ote:Oter_3027 integral membrane protein; hypothetical protein 5086162 7118244 Mchl_4794 Methylobacterium extorquens CM4 hypothetical protein YP_002423494.1 5085872 R 440085 CDS YP_002423495.1 218532679 7118245 5086868..5087272 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_0155 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 5087272 7118245 Mchl_4795 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002423495.1 5086868 D 440085 CDS YP_002423496.1 218532680 7118247 5087911..5088378 1 NC_011757.1 KEGG: mex:Mext_0110 hypothetical protein; hypothetical protein 5088378 7118247 Mchl_4797 Methylobacterium extorquens CM4 hypothetical protein YP_002423496.1 5087911 D 440085 CDS YP_002423497.1 218532681 7118248 complement(5088992..5089354) 1 NC_011757.1 SMART: response regulator receiver; KEGG: mex:Mext_0109 response regulator receiver; response regulator receiver protein 5089354 7118248 Mchl_4798 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423497.1 5088992 R 440085 CDS YP_002423498.1 218532682 7118249 complement(5089351..5091213) 1 NC_011757.1 KEGG: mex:Mext_0108 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 5091213 7118249 Mchl_4799 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002423498.1 5089351 R 440085 CDS YP_002423499.1 218532683 7118250 5092824..5095370 1 NC_011757.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mrd:Mrad2831_2714 TonB-dependent receptor; TonB-dependent receptor 5095370 7118250 Mchl_4800 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002423499.1 5092824 D 440085 CDS YP_002423500.1 218532684 7118251 complement(5096018..5097055) 1 NC_011757.1 KEGG: met:M446_0104 hypothetical protein; hypothetical protein 5097055 7118251 Mchl_4801 Methylobacterium extorquens CM4 hypothetical protein YP_002423500.1 5096018 R 440085 CDS YP_002423501.1 218532685 7118252 complement(5097052..5099010) 1 NC_011757.1 KEGG: met:M446_0104 hypothetical protein; hypothetical protein 5099010 7118252 Mchl_4802 Methylobacterium extorquens CM4 hypothetical protein YP_002423501.1 5097052 R 440085 CDS YP_002423502.1 218532686 7118253 complement(5098995..5100152) 1 NC_011757.1 PFAM: glycoside hydrolase family 8; KEGG: met:M446_0105 cellulase; cellulase 5100152 7118253 Mchl_4803 Methylobacterium extorquens CM4 cellulase YP_002423502.1 5098995 R 440085 CDS YP_002423503.1 218532687 7118254 complement(5100152..5102683) 1 NC_011757.1 PFAM: cellulose synthase subunit B; KEGG: met:M446_0106 hypothetical protein; cellulose synthase subunit B 5102683 7118254 Mchl_4804 Methylobacterium extorquens CM4 cellulose synthase subunit B YP_002423503.1 5100152 R 440085 CDS YP_002423504.1 218532688 7118255 complement(5102732..5105146) 1 NC_011757.1 KEGG: met:M446_0107 cellulose synthase catalytic subunit (UDP-forming); TIGRFAM: cellulose synthase catalytic subunit (UDP-forming); PFAM: glycosyl transferase family 2; cellulose synthase catalytic subunit 5105146 7118255 Mchl_4805 Methylobacterium extorquens CM4 cellulose synthase catalytic subunit YP_002423504.1 5102732 R 440085 CDS YP_002423505.1 218532689 7118256 complement(5105215..5105952) 1 NC_011757.1 KEGG: met:M446_0108 hypothetical protein; hypothetical protein 5105952 7118256 Mchl_4806 Methylobacterium extorquens CM4 hypothetical protein YP_002423505.1 5105215 R 440085 CDS YP_002423506.1 218532690 7118257 complement(5106163..5108541) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: met:M446_0109 response regulator receiver protein; response regulator receiver protein 5108541 7118257 Mchl_4807 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423506.1 5106163 R 440085 CDS YP_002423507.1 218532691 7118259 complement(5109841..5110926) 1 NC_011757.1 PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: mlo:mll5961 transposase; transposase IS204/IS1001/IS1096/IS1165 family protein 5110926 7118259 Mchl_4809 Methylobacterium extorquens CM4 transposase IS204/IS1001/IS1096/IS1165 family protein YP_002423507.1 5109841 R 440085 CDS YP_002423508.1 218532692 7118260 5111035..5111331 1 NC_011757.1 KEGG: mpo:Mpop_3985 hypothetical protein; hypothetical protein 5111331 7118260 Mchl_4810 Methylobacterium extorquens CM4 hypothetical protein YP_002423508.1 5111035 D 440085 CDS YP_002423509.1 218532693 7118261 5111481..5111981 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mpo:Mpop_1345 MucR family transcriptional regulator; MucR family transcriptional regulator 5111981 7118261 Mchl_4811 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002423509.1 5111481 D 440085 CDS YP_002423510.1 218532694 7118262 complement(5112434..5116705) 1 NC_011757.1 KEGG: mex:Mext_0136 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase 5116705 7118262 Mchl_4812 Methylobacterium extorquens CM4 PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase YP_002423510.1 5112434 R 440085 CDS YP_002423511.1 218532695 7118263 5116882..5117163 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: mex:Mext_3530 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 5117163 7118263 Mchl_4813 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002423511.1 5116882 D 440085 CDS YP_002423512.1 218532696 7118264 5117271..5118023 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mex:Mext_3531 integrase catalytic region; integrase catalytic subunit 5118023 7118264 Mchl_4814 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002423512.1 5117271 D 440085 CDS YP_002423513.1 218532697 7118265 5118624..5119019 1 NC_011757.1 PFAM: protein of unknown function DUF1469; KEGG: met:M446_6820 hypothetical protein; hypothetical protein 5119019 7118265 Mchl_4815 Methylobacterium extorquens CM4 hypothetical protein YP_002423513.1 5118624 D 440085 CDS YP_002423514.1 218532698 7118266 5119016..5120389 1 NC_011757.1 KEGG: met:M446_0738 hypothetical protein; hypothetical protein 5120389 7118266 Mchl_4816 Methylobacterium extorquens CM4 hypothetical protein YP_002423514.1 5119016 D 440085 CDS YP_002423515.1 218532699 7118267 5120669..5121484 1 NC_011757.1 PFAM: UspA domain protein; KEGG: mex:Mext_0489 UspA domain-containing protein; UspA domain-containing protein 5121484 7118267 Mchl_4817 Methylobacterium extorquens CM4 UspA domain-containing protein YP_002423515.1 5120669 D 440085 CDS YP_002423516.1 218532700 7118268 5122317..5123075 1 NC_011757.1 PFAM: chemotaxis sensory transducer; KEGG: mpo:Mpop_3344 methyl-accepting chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5123075 7118268 Mchl_4818 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423516.1 5122317 D 440085 CDS YP_002423517.1 218532701 7118269 complement(5123577..5123933) 1 NC_011757.1 KEGG: mrd:Mrad2831_0060 hypothetical protein; hypothetical protein 5123933 7118269 Mchl_4819 Methylobacterium extorquens CM4 hypothetical protein YP_002423517.1 5123577 R 440085 CDS YP_002423518.1 218532702 7118270 5124394..5124654 1 NC_011757.1 KEGG: mrd:Mrad2831_2038 hypothetical protein; hypothetical protein 5124654 7118270 Mchl_4820 Methylobacterium extorquens CM4 hypothetical protein YP_002423518.1 5124394 D 440085 CDS YP_002423519.1 218532703 7118271 complement(5124817..5125089) 1 NC_011757.1 KEGG: mrd:Mrad2831_4949 hypothetical protein; hypothetical protein 5125089 7118271 Mchl_4821 Methylobacterium extorquens CM4 hypothetical protein YP_002423519.1 5124817 R 440085 CDS YP_002423520.1 218532704 7118272 5126199..5126558 1 NC_011757.1 KEGG: mpo:Mpop_2346 hypothetical protein; hypothetical protein 5126558 7118272 Mchl_4822 Methylobacterium extorquens CM4 hypothetical protein YP_002423520.1 5126199 D 440085 CDS YP_002423521.1 218532705 7118273 complement(5126764..5127306) 1 NC_011757.1 KEGG: bpy:Bphyt_4763 hypothetical protein; hypothetical protein 5127306 7118273 Mchl_4823 Methylobacterium extorquens CM4 hypothetical protein YP_002423521.1 5126764 R 440085 CDS YP_002423522.1 218532706 7118274 complement(5128691..5128831) 1 NC_011757.1 hypothetical protein 5128831 7118274 Mchl_4824 Methylobacterium extorquens CM4 hypothetical protein YP_002423522.1 5128691 R 440085 CDS YP_002423523.1 218532707 7118275 complement(5129004..5129111) 1 NC_011757.1 hypothetical protein 5129111 7118275 Mchl_4825 Methylobacterium extorquens CM4 hypothetical protein YP_002423523.1 5129004 R 440085 CDS YP_002423524.1 218532708 7118276 5129239..5129397 1 NC_011757.1 KEGG: mpo:Mpop_0877 hypothetical protein; hypothetical protein 5129397 7118276 Mchl_4826 Methylobacterium extorquens CM4 hypothetical protein YP_002423524.1 5129239 D 440085 CDS YP_002423525.1 218532709 7118277 5129399..5130358 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: cak:Caul_5148 AraC family transcriptional regulator; AraC family transcriptional regulator 5130358 7118277 Mchl_4827 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002423525.1 5129399 D 440085 CDS YP_002423526.1 218532710 7118278 complement(5130636..5130779) 1 NC_011757.1 KEGG: bpt:Bpet3011 tautomerase; tautomerase 5130779 7118278 Mchl_4828 Methylobacterium extorquens CM4 tautomerase YP_002423526.1 5130636 R 440085 CDS YP_002423527.1 218532711 7118279 complement(5131041..5138069) 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; Animal haem peroxidase; KEGG: rpe:RPE_1007 heme peroxidase; heme peroxidase 5138069 7118279 Mchl_4829 Methylobacterium extorquens CM4 heme peroxidase YP_002423527.1 5131041 R 440085 CDS YP_002423528.1 218532712 7118284 5139318..5139740 1 NC_011757.1 KEGG: mpo:Mpop_4256 hypothetical protein; hypothetical protein 5139740 7118284 Mchl_4833 Methylobacterium extorquens CM4 hypothetical protein YP_002423528.1 5139318 D 440085 CDS YP_002423529.1 218532713 7118285 5139824..5140231 1 NC_011757.1 PFAM: helix-turn-helix domain protein; KEGG: mex:Mext_3522 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 5140231 7118285 Mchl_4834 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002423529.1 5139824 D 440085 CDS YP_002423530.1 218532714 7118286 5140343..5140588 1 NC_011757.1 hypothetical protein 5140588 7118286 Mchl_4835 Methylobacterium extorquens CM4 hypothetical protein YP_002423530.1 5140343 D 440085 CDS YP_002423531.1 218532715 7118288 5146360..5147043 1 NC_011757.1 PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_4361 ThiJ/PfpI domain-containing protein; ThiJ/PfpI domain-containing protein 5147043 7118288 Mchl_4837 Methylobacterium extorquens CM4 ThiJ/PfpI domain-containing protein YP_002423531.1 5146360 D 440085 CDS YP_002423532.1 218532716 7118289 5147158..5148567 1 NC_011757.1 PFAM: amidase; KEGG: msm:MSMEG_3970 glutamyl-tRNA(Gln) amidotransferase subunit A; amidase 5148567 7118289 Mchl_4838 Methylobacterium extorquens CM4 amidase YP_002423532.1 5147158 D 440085 CDS YP_002423533.1 218532717 7118290 complement(5148826..5149512) 1 NC_011757.1 PFAM: peptidase membrane zinc metallopeptidase KEGG: mex:Mext_4363 peptidase membrane zinc metallopeptidase; peptidase membrane zinc metallopeptidase 5149512 7118290 Mchl_4839 Methylobacterium extorquens CM4 peptidase membrane zinc metallopeptidase YP_002423533.1 5148826 R 440085 CDS YP_002423534.1 218532718 7118291 complement(5149736..5151352) 1 NC_011757.1 PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: mex:Mext_4364 thioredoxin-disulfide reductase; cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5151352 7118291 Mchl_4840 Methylobacterium extorquens CM4 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002423534.1 5149736 R 440085 CDS YP_002423535.1 218532719 7118292 complement(5151649..5152554) 1 NC_011757.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mex:Mext_4365 helix-turn-helix domain-containing protein; AraC family transcriptional regulator 5152554 7118292 Mchl_4841 Methylobacterium extorquens CM4 AraC family transcriptional regulator YP_002423535.1 5151649 R 440085 CDS YP_002423536.1 218532720 7118293 5152709..5153287 1 NC_011757.1 KEGG: mex:Mext_4366 hypothetical protein; hypothetical protein 5153287 7118293 Mchl_4842 Methylobacterium extorquens CM4 hypothetical protein YP_002423536.1 5152709 D 440085 CDS YP_002423537.1 218532721 7118294 complement(5153468..5154730) 1 NC_011757.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_4367 amine oxidase; amine oxidase 5154730 7118294 Mchl_4843 Methylobacterium extorquens CM4 amine oxidase YP_002423537.1 5153468 R 440085 CDS YP_002423538.1 218532722 7118295 5155035..5155763 1 NC_011757.1 PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_4368 ThiJ/PfpI domain-containing protein; ThiJ/PfpI domain-containing protein 5155763 7118295 Mchl_4844 Methylobacterium extorquens CM4 ThiJ/PfpI domain-containing protein YP_002423538.1 5155035 D 440085 CDS YP_002423539.1 218532723 7118296 complement(5156195..5156623) 1 NC_011757.1 KEGG: mex:Mext_4369 hypothetical protein; hypothetical protein 5156623 7118296 Mchl_4845 Methylobacterium extorquens CM4 hypothetical protein YP_002423539.1 5156195 R 440085 CDS YP_002423540.1 218532724 7118297 5156835..5157860 1 NC_011757.1 KEGG: mex:Mext_4370 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components-like protein; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 5157860 7118297 Mchl_4846 Methylobacterium extorquens CM4 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_002423540.1 5156835 D 440085 CDS YP_002423541.1 218532725 7118298 5157880..5158632 1 NC_011757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4371 binding-protein-dependent transport systems inner membrane component; ABC transporter inner membrane protein 5158632 7118298 Mchl_4847 Methylobacterium extorquens CM4 ABC transporter inner membrane protein YP_002423541.1 5157880 D 440085 CDS YP_002423542.1 218532726 7118299 5158629..5159390 1 NC_011757.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_4372 ABC transporter; ABC transporter 5159390 7118299 Mchl_4848 Methylobacterium extorquens CM4 ABC transporter YP_002423542.1 5158629 D 440085 CDS YP_002423543.1 218532727 7118300 5159504..5159938 1 NC_011757.1 KEGG: mex:Mext_4373 hypothetical protein; hypothetical protein 5159938 7118300 Mchl_4849 Methylobacterium extorquens CM4 hypothetical protein YP_002423543.1 5159504 D 440085 CDS YP_002423544.1 218532728 7118301 5160078..5160269 1 NC_011757.1 KEGG: mex:Mext_4374 hypothetical protein; hypothetical protein 5160269 7118301 Mchl_4850 Methylobacterium extorquens CM4 hypothetical protein YP_002423544.1 5160078 D 440085 CDS YP_002423545.1 218532729 7118302 complement(5160573..5162192) 1 NC_011757.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: mex:Mext_4375 peptide chain release factor 3; peptide chain release factor 3 5162192 7118302 Mchl_4851 Methylobacterium extorquens CM4 peptide chain release factor 3 YP_002423545.1 5160573 R 440085 CDS YP_002423546.1 218532730 7118303 complement(5162299..5163042) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4376 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5163042 7118303 Mchl_4852 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423546.1 5162299 R 440085 CDS YP_002423547.1 218532731 7118305 complement(5163672..5164160) 1 NC_011757.1 KEGG: mex:Mext_4390 hypothetical protein; hypothetical protein 5164160 7118305 Mchl_4853 Methylobacterium extorquens CM4 hypothetical protein YP_002423547.1 5163672 R 440085 CDS YP_002423548.1 218532732 7118307 complement(5165588..5166778) 1 NC_011757.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5166778 7118307 Mchl_4855 Methylobacterium extorquens CM4 elongation factor Tu YP_002423548.1 5165588 R 440085 CDS YP_002423549.1 218532733 7118308 complement(5166901..5167176) 1 NC_011757.1 PFAM: RNA-binding S4 domain protein; KEGG: mex:Mext_4393 RNA-binding S4 domain-containing protein; RNA-binding S4 domain-containing protein 5167176 7118308 Mchl_4856 Methylobacterium extorquens CM4 RNA-binding S4 domain-containing protein YP_002423549.1 5166901 R 440085 CDS YP_002423550.1 218532734 7118309 complement(5167253..5170663) 1 NC_011757.1 PFAM: helicase; KEGG: mex:Mext_4394 helicase domain-containing protein; helicase 5170663 7118309 Mchl_4857 Methylobacterium extorquens CM4 helicase YP_002423550.1 5167253 R 440085 CDS YP_002423551.1 218532735 7114279 complement(5170853..5171197) 1 NC_011757.1 KEGG: mex:Mext_4395 hypothetical protein; hypothetical protein 5171197 7114279 Mchl_4858 Methylobacterium extorquens CM4 hypothetical protein YP_002423551.1 5170853 R 440085 CDS YP_002423552.1 218532736 7114280 complement(5171413..5172309) 1 NC_011757.1 KEGG: mex:Mext_4396 hypothetical protein; hypothetical protein 5172309 7114280 Mchl_4859 Methylobacterium extorquens CM4 hypothetical protein YP_002423552.1 5171413 R 440085 CDS YP_002423553.1 218532737 7114281 5172574..5173119 1 NC_011757.1 PFAM: Heme NO binding domain protein; KEGG: mex:Mext_4397 heme NO binding domain-containing protein; heme NO binding domain-containing protein 5173119 7114281 Mchl_4860 Methylobacterium extorquens CM4 heme NO binding domain-containing protein YP_002423553.1 5172574 D 440085 CDS YP_002423554.1 218532738 7114282 5173127..5174671 1 NC_011757.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_4398 diguanylate cyclase; diguanylate cyclase/phosphodiesterase 5174671 7114282 Mchl_4861 Methylobacterium extorquens CM4 diguanylate cyclase/phosphodiesterase YP_002423554.1 5173127 D 440085 CDS YP_002423555.1 218532739 7114283 complement(5174685..5175686) 1 NC_011757.1 PFAM: glucokinase; KEGG: mex:Mext_4399 glucokinase; glucokinase 5175686 7114283 Mchl_4862 Methylobacterium extorquens CM4 glucokinase YP_002423555.1 5174685 R 440085 CDS YP_002423556.1 218532740 7114284 complement(5175777..5176532) 1 NC_011757.1 KEGG: mex:Mext_4400 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: trehalose-phosphatase; HAD-superfamily hydrolase 5176532 7114284 Mchl_4863 Methylobacterium extorquens CM4 HAD-superfamily hydrolase YP_002423556.1 5175777 R 440085 CDS YP_002423557.1 218532741 7114285 5176619..5177113 1 NC_011757.1 PFAM: protein of unknown function DUF427; KEGG: mex:Mext_4401 hypothetical protein; hypothetical protein 5177113 7114285 Mchl_4864 Methylobacterium extorquens CM4 hypothetical protein YP_002423557.1 5176619 D 440085 CDS YP_002423558.1 218532742 7114286 5177374..5178591 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_4402 beta-lactamase; beta-lactamase 5178591 7114286 Mchl_4865 Methylobacterium extorquens CM4 beta-lactamase YP_002423558.1 5177374 D 440085 CDS YP_002423559.1 218532743 7114287 5178762..5180741 1 NC_011757.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: mex:Mext_4403 choline/carnitine/betaine transporter; choline/carnitine/betaine transporter 5180741 7114287 Mchl_4866 Methylobacterium extorquens CM4 choline/carnitine/betaine transporter YP_002423559.1 5178762 D 440085 CDS YP_002423560.1 218532744 7114288 5181236..5181709 1 NC_011757.1 PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: mex:Mext_4404 NADH dehydrogenase (ubiquinone) 24 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit 5181709 7114288 Mchl_4867 Methylobacterium extorquens CM4 NADH dehydrogenase (ubiquinone) 24 kDa subunit YP_002423560.1 5181236 D 440085 CDS YP_002423561.1 218532745 7114289 5181706..5183265 1 NC_011757.1 PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mex:Mext_4405 NADH dehydrogenase (quinone); NADH dehydrogenase (quinone) 5183265 7114289 Mchl_4868 Methylobacterium extorquens CM4 NADH dehydrogenase (quinone) YP_002423561.1 5181706 D 440085 CDS YP_002423562.1 218532746 7114290 5183278..5186130 1 NC_011757.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; 4Fe-4S ferredoxin iron-sulphur binding, conserved site; KEGG: mex:Mext_4406 formate dehydrogenase, alpha subunit; formate dehydrogenase subunit alpha 5186130 7114290 Mchl_4869 Methylobacterium extorquens CM4 formate dehydrogenase subunit alpha YP_002423562.1 5183278 D 440085 CDS YP_002423563.1 218532747 7114291 5186238..5186528 1 NC_011757.1 KEGG: mex:Mext_4407 hypothetical protein; hypothetical protein 5186528 7114291 Mchl_4870 Methylobacterium extorquens CM4 hypothetical protein YP_002423563.1 5186238 D 440085 CDS YP_002423564.1 218532748 7114292 5186620..5187555 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4408 LysR substrate-binding; LysR family transcriptional regulator 5187555 7114292 Mchl_4871 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423564.1 5186620 D 440085 CDS YP_002423565.1 218532749 7114293 complement(5187628..5188074) 1 NC_011757.1 KEGG: mex:Mext_4409 hypothetical protein; hypothetical protein 5188074 7114293 Mchl_4872 Methylobacterium extorquens CM4 hypothetical protein YP_002423565.1 5187628 R 440085 CDS YP_002423566.1 218532750 7114294 complement(5188142..5189176) 1 NC_011757.1 TIGRFAM: small GTP-binding protein; GTP-binding protein Obg/CgtA; PFAM: GTP-binding protein HSR1-related; GTP1/OBG sub domain protein; KEGG: mex:Mext_4410 GTP-binding protein Obg/CgtA; GTP-binding protein Obg/CgtA 5189176 7114294 Mchl_4873 Methylobacterium extorquens CM4 GTP-binding protein Obg/CgtA YP_002423566.1 5188142 R 440085 CDS YP_002423567.1 218532751 7114295 complement(5189213..5189692) 1 NC_011757.1 KEGG: mex:Mext_4411 hypothetical protein; hypothetical protein 5189692 7114295 Mchl_4874 Methylobacterium extorquens CM4 hypothetical protein YP_002423567.1 5189213 R 440085 CDS YP_002423568.1 218532752 7114296 complement(5189689..5190288) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mex:Mext_4412 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 5190288 7114296 Mchl_4875 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002423568.1 5189689 R 440085 CDS YP_002423569.1 218532753 7114297 complement(5190477..5190743) 1 NC_011757.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 5190743 rpmA 7114297 rpmA Methylobacterium extorquens CM4 50S ribosomal protein L27 YP_002423569.1 5190477 R 440085 CDS YP_002423570.1 218532754 7114298 complement(5190792..5191184) 1 NC_011757.1 PFAM: ribosomal protein L21; KEGG: mex:Mext_4414 ribosomal protein L21; 50S ribosomal protein L21 5191184 rplU 7114298 rplU Methylobacterium extorquens CM4 50S ribosomal protein L21 YP_002423570.1 5190792 R 440085 CDS YP_002423571.1 218532755 7114299 complement(5191380..5192945) 1 NC_011757.1 PFAM: protein of unknown function DUF853 NPT hydrolase KEGG: mex:Mext_4415 protein of unknown function DUF853 NPT hydrolase; hypothetical protein 5192945 7114299 Mchl_4878 Methylobacterium extorquens CM4 hypothetical protein YP_002423571.1 5191380 R 440085 CDS YP_002423572.1 218532756 7114300 5193100..5193486 1 NC_011757.1 KEGG: mex:Mext_4416 hypothetical protein; hypothetical protein 5193486 7114300 Mchl_4879 Methylobacterium extorquens CM4 hypothetical protein YP_002423572.1 5193100 D 440085 CDS YP_002423573.1 218532757 7114301 5193699..5194697 1 NC_011757.1 KEGG: mex:Mext_4417 hypothetical protein; hypothetical protein 5194697 7114301 Mchl_4880 Methylobacterium extorquens CM4 hypothetical protein YP_002423573.1 5193699 D 440085 CDS YP_002423574.1 218532758 7114302 5194774..5195943 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4418 major facilitator transporter; major facilitator superfamily protein 5195943 7114302 Mchl_4881 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423574.1 5194774 D 440085 CDS YP_002423575.1 218532759 7114303 5196045..5196173 1 NC_011757.1 KEGG: mpo:Mpop_4928 hypothetical protein; hypothetical protein 5196173 7114303 Mchl_4882 Methylobacterium extorquens CM4 hypothetical protein YP_002423575.1 5196045 D 440085 CDS YP_002423576.1 218532760 7114304 5196527..5196775 1 NC_011757.1 KEGG: mex:Mext_4419 hypothetical protein; hypothetical protein 5196775 7114304 Mchl_4883 Methylobacterium extorquens CM4 hypothetical protein YP_002423576.1 5196527 D 440085 CDS YP_002423577.1 218532761 7114305 complement(5196788..5197981) 1 NC_011757.1 PFAM: patatin; KEGG: mex:Mext_4420 patatin; patatin 5197981 7114305 Mchl_4884 Methylobacterium extorquens CM4 patatin YP_002423577.1 5196788 R 440085 CDS YP_002423578.1 218532762 7114306 5198439..5198990 1 NC_011757.1 KEGG: mex:Mext_4421 hypothetical protein; hypothetical protein 5198990 7114306 Mchl_4885 Methylobacterium extorquens CM4 hypothetical protein YP_002423578.1 5198439 D 440085 CDS YP_002423579.1 218532763 7114307 5199195..5199410 1 NC_011757.1 KEGG: mex:Mext_4422 hypothetical protein; hypothetical protein 5199410 7114307 Mchl_4886 Methylobacterium extorquens CM4 hypothetical protein YP_002423579.1 5199195 D 440085 CDS YP_002423580.1 218532764 7114308 5199407..5199925 1 NC_011757.1 KEGG: mex:Mext_4423 hypothetical protein; hypothetical protein 5199925 7114308 Mchl_4887 Methylobacterium extorquens CM4 hypothetical protein YP_002423580.1 5199407 D 440085 CDS YP_002423581.1 218532765 7114309 5200002..5200901 1 NC_011757.1 PFAM: diacylglycerol kinase; KEGG: mex:Mext_4424 diacylglycerol kinase; diacylglycerol kinase 5200901 7114309 Mchl_4888 Methylobacterium extorquens CM4 diacylglycerol kinase YP_002423581.1 5200002 D 440085 CDS YP_002423582.1 218532766 7114310 5200898..5201782 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_4425 metallophosphoesterase; metallophosphoesterase 5201782 7114310 Mchl_4889 Methylobacterium extorquens CM4 metallophosphoesterase YP_002423582.1 5200898 D 440085 CDS YP_002423583.1 218532767 7114311 complement(5201810..5203270) 1 NC_011757.1 PFAM: Na+/solute symporter; KEGG: mex:Mext_4426 Na+/solute symporter; Na+/solute symporter 5203270 7114311 Mchl_4890 Methylobacterium extorquens CM4 Na+/solute symporter YP_002423583.1 5201810 R 440085 CDS YP_002423584.1 218532768 7114312 complement(5203267..5203470) 1 NC_011757.1 KEGG: mex:Mext_4427 hypothetical protein; hypothetical protein 5203470 7114312 Mchl_4891 Methylobacterium extorquens CM4 hypothetical protein YP_002423584.1 5203267 R 440085 CDS YP_002423585.1 218532769 7114313 complement(5203650..5205752) 1 NC_011757.1 KEGG: mex:Mext_4428 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAS/PAC sensor hybrid histidine kinase 5205752 7114313 Mchl_4892 Methylobacterium extorquens CM4 PAS/PAC sensor hybrid histidine kinase YP_002423585.1 5203650 R 440085 CDS YP_002423586.1 218532770 7114314 complement(5205956..5206405) 1 NC_011757.1 KEGG: mex:Mext_4429 hypothetical protein; hypothetical protein 5206405 7114314 Mchl_4893 Methylobacterium extorquens CM4 hypothetical protein YP_002423586.1 5205956 R 440085 CDS YP_002423587.1 218532771 7114315 complement(5206467..5207213) 1 NC_011757.1 PFAM: nucleotidyl transferase; KEGG: mex:Mext_4430 nucleotidyl transferase; nucleotidyl transferase 5207213 7114315 Mchl_4894 Methylobacterium extorquens CM4 nucleotidyl transferase YP_002423587.1 5206467 R 440085 CDS YP_002423588.1 218532772 7114316 complement(5207247..5208875) 1 NC_011757.1 PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: mex:Mext_4431 hypothetical protein; hypothetical protein 5208875 7114316 Mchl_4895 Methylobacterium extorquens CM4 hypothetical protein YP_002423588.1 5207247 R 440085 CDS YP_002423589.1 218532773 7114317 complement(5209135..5211663) 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; SMART: PAS domain containing protein; KEGG: mex:Mext_4432 ATPase domain-containing protein; PAS/PAC sensor signal transduction histidine kinase 5211663 7114317 Mchl_4896 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002423589.1 5209135 R 440085 CDS YP_002423590.1 218532774 7114318 complement(5212153..5213559) 1 NC_011757.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 5213559 7114318 Mchl_4897 Methylobacterium extorquens CM4 S-adenosyl-L-homocysteine hydrolase YP_002423590.1 5212153 R 440085 CDS YP_002423591.1 218532775 7114319 complement(5213729..5215417) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_4434 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5215417 7114319 Mchl_4898 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002423591.1 5213729 R 440085 CDS YP_002423592.1 218532776 7114320 complement(5215495..5216106) 1 NC_011757.1 PFAM: nitroreductase; KEGG: mex:Mext_4435 nitroreductase; nitroreductase 5216106 7114320 Mchl_4899 Methylobacterium extorquens CM4 nitroreductase YP_002423592.1 5215495 R 440085 CDS YP_002423593.1 218532777 7114321 5216350..5217150 1 NC_011757.1 PFAM: enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_4436 enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase 5217150 7114321 Mchl_4900 Methylobacterium extorquens CM4 enoyl-CoA hydratase/isomerase YP_002423593.1 5216350 D 440085 CDS YP_002423594.1 218532778 7114322 5217257..5218036 1 NC_011757.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: mex:Mext_4437 endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 5218036 7114322 Mchl_4901 Methylobacterium extorquens CM4 endonuclease/exonuclease/phosphatase YP_002423594.1 5217257 D 440085 CDS YP_002423595.1 218532779 7114323 complement(5217927..5219363) 1 NC_011757.1 PFAM: phospholipase D/transphosphatidylase; KEGG: mex:Mext_4438 phospholipase D/transphosphatidylase; phospholipase D/transphosphatidylase 5219363 7114323 Mchl_4902 Methylobacterium extorquens CM4 phospholipase D/transphosphatidylase YP_002423595.1 5217927 R 440085 CDS YP_002423596.1 218532780 7114324 5219589..5222732 1 NC_011757.1 TIGRFAM: double-strand break repair protein AddB; KEGG: mex:Mext_4439 double-strand break repair protein AddB; double-strand break repair protein AddB 5222732 7114324 Mchl_4903 Methylobacterium extorquens CM4 double-strand break repair protein AddB YP_002423596.1 5219589 D 440085 CDS YP_002423597.1 218532781 7114325 5222729..5226172 1 NC_011757.1 TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: mex:Mext_4440 double-strand break repair helicase AddA; double-strand break repair helicase AddA 5226172 7114325 Mchl_4904 Methylobacterium extorquens CM4 double-strand break repair helicase AddA YP_002423597.1 5222729 D 440085 CDS YP_002423598.1 218532782 7114326 complement(5226269..5227555) 1 NC_011757.1 PFAM: glucose sorbosone dehydrogenase; KEGG: mex:Mext_4441 glucose sorbosone dehydrogenase; glucose sorbosone dehydrogenase 5227555 7114326 Mchl_4905 Methylobacterium extorquens CM4 glucose sorbosone dehydrogenase YP_002423598.1 5226269 R 440085 CDS YP_002423599.1 218532783 7114327 5227931..5228251 1 NC_011757.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: mex:Mext_4442 thioredoxin; thioredoxin 5228251 7114327 Mchl_4906 Methylobacterium extorquens CM4 thioredoxin YP_002423599.1 5227931 D 440085 CDS YP_002423600.1 218532784 7114328 complement(5228409..5229299) 1 NC_011757.1 KEGG: mex:Mext_4443 porin; porin 5229299 7114328 Mchl_4907 Methylobacterium extorquens CM4 porin YP_002423600.1 5228409 R 440085 CDS YP_002423601.1 218532785 7114329 complement(5229688..5231013) 1 NC_011757.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: mex:Mext_4444 FolC bifunctional protein; FolC bifunctional protein 5231013 7114329 Mchl_4908 Methylobacterium extorquens CM4 FolC bifunctional protein YP_002423601.1 5229688 R 440085 CDS YP_002423602.1 218532786 7114330 complement(5231046..5231969) 1 NC_011757.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, subunit beta; KEGG: mex:Mext_4445 acetyl-CoA carboxylase, carboxyl transferase subunit beta; acetyl-CoA carboxylase, carboxyl transferase subunit beta 5231969 7114330 Mchl_4909 Methylobacterium extorquens CM4 acetyl-CoA carboxylase, carboxyl transferase subunit beta YP_002423602.1 5231046 R 440085 CDS YP_002423603.1 218532787 7114331 complement(5232080..5232922) 1 NC_011757.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 5232922 trpA 7114331 trpA Methylobacterium extorquens CM4 tryptophan synthase subunit alpha YP_002423603.1 5232080 R 440085 CDS YP_002423604.1 218532788 7114332 complement(5233094..5234053) 1 NC_011757.1 PFAM: NUDIX hydrolase; NADH pyrophosphatase-like ; Zinc ribbon NADH pyrophosphatase; KEGG: mex:Mext_4447 NUDIX hydrolase; NUDIX hydrolase 5234053 7114332 Mchl_4911 Methylobacterium extorquens CM4 NUDIX hydrolase YP_002423604.1 5233094 R 440085 CDS YP_002423605.1 218532789 7114333 complement(5234064..5234480) 1 NC_011757.1 PFAM: histidine triad (HIT) protein; KEGG: mex:Mext_4448 histidine triad (HIT) protein; histidine triad (HIT) protein 5234480 7114333 Mchl_4912 Methylobacterium extorquens CM4 histidine triad (HIT) protein YP_002423605.1 5234064 R 440085 CDS YP_002423606.1 218532790 7114334 5234657..5235721 1 NC_011757.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mex:Mext_4449 metal-dependent phosphohydrolase; response regulator receiver modulated metal dependent phosphohydrolase 5235721 7114334 Mchl_4913 Methylobacterium extorquens CM4 response regulator receiver modulated metal dependent phosphohydrolase YP_002423606.1 5234657 D 440085 CDS YP_002423607.1 218532791 7114335 5236060..5237766 1 NC_011757.1 PFAM: helicase; DbpA RNA-binding domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: mex:Mext_4450 DEAD/DEAH box helicase domain-containing protein; DEAD/DEAH box helicase 5237766 7114335 Mchl_4914 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002423607.1 5236060 D 440085 CDS YP_002423608.1 218532792 7114336 complement(5237863..5238753) 1 NC_011757.1 KEGG: mex:Mext_4451 hypothetical protein; hypothetical protein 5238753 7114336 Mchl_4915 Methylobacterium extorquens CM4 hypothetical protein YP_002423608.1 5237863 R 440085 CDS YP_002423609.1 218532793 7114337 5239181..5240710 1 NC_011757.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mex:Mext_4452 ATPase domain-containing protein; histidine kinase 5240710 7114337 Mchl_4916 Methylobacterium extorquens CM4 histidine kinase YP_002423609.1 5239181 D 440085 CDS YP_002423610.1 218532794 7114338 5240745..5241410 1 NC_011757.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mex:Mext_4453 response regulator receiver; LuxR family transcriptional regulator 5241410 7114338 Mchl_4917 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423610.1 5240745 D 440085 CDS YP_002423611.1 218532795 7114339 5241438..5242121 1 NC_011757.1 PFAM: TENA/THI-4 domain protein; KEGG: mex:Mext_4454 TenA/THI-4 domain-containing protein; TenA family transcriptional regulator 5242121 7114339 Mchl_4918 Methylobacterium extorquens CM4 TenA family transcriptional regulator YP_002423611.1 5241438 D 440085 CDS YP_002423612.1 218532796 7114340 5242286..5243776 1 NC_011757.1 PFAM: amino acid permease-associated region; KEGG: mex:Mext_4455 amino acid permease-associated region; amino acid permease-associated protein 5243776 7114340 Mchl_4919 Methylobacterium extorquens CM4 amino acid permease-associated protein YP_002423612.1 5242286 D 440085 CDS YP_002423613.1 218532797 7114341 complement(5243976..5244881) 1 NC_011757.1 PFAM: beta-lactamase; KEGG: mex:Mext_4456 beta-lactamase domain-containing protein; beta-lactamase 5244881 7114341 Mchl_4920 Methylobacterium extorquens CM4 beta-lactamase YP_002423613.1 5243976 R 440085 CDS YP_002423614.1 218532798 7114342 complement(5245073..5246293) 1 NC_011757.1 KEGG: mex:Mext_4457 hypothetical protein; hypothetical protein 5246293 7114342 Mchl_4921 Methylobacterium extorquens CM4 hypothetical protein YP_002423614.1 5245073 R 440085 CDS YP_002423615.1 218532799 7114343 complement(5246389..5248992) 1 NC_011757.1 KEGG: mex:Mext_4458 ABC-type multidrug transporter ATPase and permeases-like protein; multidrug ABC transporter ATPase/permease 5248992 7114343 Mchl_4922 Methylobacterium extorquens CM4 multidrug ABC transporter ATPase/permease YP_002423615.1 5246389 R 440085 CDS YP_002423616.1 218532800 7114344 5249429..5251357 1 NC_011757.1 KEGG: mex:Mext_4459 hypothetical protein; hypothetical protein 5251357 7114344 Mchl_4923 Methylobacterium extorquens CM4 hypothetical protein YP_002423616.1 5249429 D 440085 CDS YP_002423617.1 218532801 7114345 5251354..5252583 1 NC_011757.1 KEGG: mex:Mext_4460 hypothetical protein; hypothetical protein 5252583 7114345 Mchl_4924 Methylobacterium extorquens CM4 hypothetical protein YP_002423617.1 5251354 D 440085 CDS YP_002423618.1 218532802 7114346 5252642..5253463 1 NC_011757.1 PFAM: glutamine amidotransferase class-II; KEGG: mex:Mext_4461 glutamine amidotransferase class-II; class II glutamine amidotransferase 5253463 7114346 Mchl_4925 Methylobacterium extorquens CM4 class II glutamine amidotransferase YP_002423618.1 5252642 D 440085 CDS YP_002423619.1 218532803 7114347 5253711..5254445 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_4462 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 5254445 7114347 Mchl_4926 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002423619.1 5253711 D 440085 CDS YP_002423620.1 218532804 7114348 complement(5255155..5255688) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_4463 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 5255688 7114348 Mchl_4927 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002423620.1 5255155 R 440085 CDS YP_002423621.1 218532805 7114349 complement(5256060..5256458) 1 NC_011757.1 KEGG: mex:Mext_4464 hypothetical protein; hypothetical protein 5256458 7114349 Mchl_4928 Methylobacterium extorquens CM4 hypothetical protein YP_002423621.1 5256060 R 440085 CDS YP_002423622.1 218532806 7114350 5256694..5257869 1 NC_011757.1 KEGG: mex:Mext_4465 hypothetical protein; hypothetical protein 5257869 7114350 Mchl_4929 Methylobacterium extorquens CM4 hypothetical protein YP_002423622.1 5256694 D 440085 CDS YP_002423623.1 218532807 7114351 complement(5258028..5258348) 1 NC_011757.1 PFAM: ferredoxin; KEGG: mex:Mext_4466 ferredoxin; ferredoxin 5258348 7114351 Mchl_4930 Methylobacterium extorquens CM4 ferredoxin YP_002423623.1 5258028 R 440085 CDS YP_002423624.1 218532808 7114352 complement(5258564..5259121) 1 NC_011757.1 PFAM: Hpt domain protein; KEGG: mex:Mext_4467 Hpt domain-containing protein; CheA signal transduction histidine kinase 5259121 7114352 Mchl_4931 Methylobacterium extorquens CM4 CheA signal transduction histidine kinase YP_002423624.1 5258564 R 440085 CDS YP_002423625.1 218532809 7114353 5259270..5267663 1 NC_011757.1 PFAM: Apolipoprotein A1/A4/E; KEGG: mex:Mext_4468 hypothetical protein; Apolipoprotein A1/A4/E 5267663 7114353 Mchl_4932 Methylobacterium extorquens CM4 Apolipoprotein A1/A4/E YP_002423625.1 5259270 D 440085 CDS YP_002423626.1 218532810 7114354 complement(5267819..5268448) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: mex:Mext_4469 helix-turn-helix domain-containing protein; XRE family transcriptional regulator 5268448 7114354 Mchl_4933 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002423626.1 5267819 R 440085 CDS YP_002423627.1 218532811 7114355 complement(5268625..5269431) 1 NC_011757.1 KEGG: mex:Mext_4470 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; phosphomethylpyrimidine kinase 5269431 7114355 Mchl_4934 Methylobacterium extorquens CM4 phosphomethylpyrimidine kinase YP_002423627.1 5268625 R 440085 CDS YP_002423628.1 218532812 7114356 complement(5269479..5270204) 1 NC_011757.1 PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_4471 thiamine-phosphate diphosphorylase; thiamine-phosphate diphosphorylase 5270204 7114356 Mchl_4935 Methylobacterium extorquens CM4 thiamine-phosphate diphosphorylase YP_002423628.1 5269479 R 440085 CDS YP_002423629.1 218532813 7114357 5270330..5271436 1 NC_011757.1 KEGG: mex:Mext_4472 hypothetical protein; hypothetical protein 5271436 7114357 Mchl_4936 Methylobacterium extorquens CM4 hypothetical protein YP_002423629.1 5270330 D 440085 CDS YP_002423630.1 218532814 7114358 complement(5271501..5271776) 1 NC_011757.1 KEGG: mex:Mext_4473 hypothetical protein; hypothetical protein 5271776 7114358 Mchl_4937 Methylobacterium extorquens CM4 hypothetical protein YP_002423630.1 5271501 R 440085 CDS YP_002423631.1 218532815 7114359 complement(5272094..5272624) 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_4474 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 5272624 7114359 Mchl_4938 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002423631.1 5272094 R 440085 CDS YP_002423632.1 218532816 7114360 complement(5273560..5274504) 1 NC_011757.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 5274504 7114360 Mchl_4939 Methylobacterium extorquens CM4 N-acetyl-gamma-glutamyl-phosphate reductase YP_002423632.1 5273560 R 440085 CDS YP_002423633.1 218532817 7116960 5274758..5275297 1 NC_011757.1 KEGG: mex:Mext_4476 hypothetical protein; hypothetical protein 5275297 7116960 Mchl_4940 Methylobacterium extorquens CM4 hypothetical protein YP_002423633.1 5274758 D 440085 CDS YP_002423634.1 218532818 7114938 complement(5275351..5276160) 1 NC_011757.1 TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_4477 molybdenum ABC transporter periplasmic molybdate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 5276160 7114938 Mchl_4941 Methylobacterium extorquens CM4 molybdenum ABC transporter periplasmic molybdate-binding protein YP_002423634.1 5275351 R 440085 CDS YP_002423635.1 218532819 7114939 complement(5276329..5276499) 1 NC_011757.1 KEGG: mex:Mext_4478 hypothetical protein; hypothetical protein 5276499 7114939 Mchl_4942 Methylobacterium extorquens CM4 hypothetical protein YP_002423635.1 5276329 R 440085 CDS YP_002423636.1 218532820 7114940 complement(5276592..5276792) 1 NC_011757.1 KEGG: mpo:Mpop_4992 hypothetical protein; hypothetical protein 5276792 7114940 Mchl_4943 Methylobacterium extorquens CM4 hypothetical protein YP_002423636.1 5276592 R 440085 CDS YP_002423637.1 218532821 7114941 5277117..5278034 1 NC_011757.1 PFAM: ribosomal L11 methyltransferase; KEGG: mex:Mext_4479 ribosomal L11 methyltransferase; ribosomal L11 methyltransferase 5278034 7114941 Mchl_4944 Methylobacterium extorquens CM4 ribosomal L11 methyltransferase YP_002423637.1 5277117 D 440085 CDS YP_002423638.1 218532822 7114942 5278276..5280114 1 NC_011757.1 PFAM: creatinase; peptidase M24; KEGG: mex:Mext_4480 peptidase M24; peptidase M24 5280114 7114942 Mchl_4945 Methylobacterium extorquens CM4 peptidase M24 YP_002423638.1 5278276 D 440085 CDS YP_002423639.1 218532823 7114943 5280111..5280590 1 NC_011757.1 PFAM: protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_4481 low molecular weight phosphotyrosine protein phosphatase; protein tyrosine phosphatase 5280590 7114943 Mchl_4946 Methylobacterium extorquens CM4 protein tyrosine phosphatase YP_002423639.1 5280111 D 440085 CDS YP_002423640.1 218532824 7114944 5280587..5281393 1 NC_011757.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: mex:Mext_4482 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5281393 7114944 Mchl_4947 Methylobacterium extorquens CM4 aminoglycoside phosphotransferase YP_002423640.1 5280587 D 440085 CDS YP_002423641.1 218532825 7114945 complement(5281559..5283673) 1 NC_011757.1 PFAM: ABC transporter; SbmABacA family protein; ABC transporter; SMART: ATPase AAA; KEGG: mex:Mext_4485 ABC transporter; ABC transporter 5283673 7114945 Mchl_4948 Methylobacterium extorquens CM4 ABC transporter YP_002423641.1 5281559 R 440085 CDS YP_002423642.1 218532826 7114946 complement(5283946..5284275) 1 NC_011757.1 KEGG: mex:Mext_4486 hypothetical protein; hypothetical protein 5284275 7114946 Mchl_4949 Methylobacterium extorquens CM4 hypothetical protein YP_002423642.1 5283946 R 440085 CDS YP_002423643.1 218532827 7114947 5284509..5285222 1 NC_011757.1 KEGG: mex:Mext_4487 hypothetical protein; hypothetical protein 5285222 7114947 Mchl_4950 Methylobacterium extorquens CM4 hypothetical protein YP_002423643.1 5284509 D 440085 CDS YP_002423644.1 218532828 7114948 complement(5285230..5286150) 1 NC_011757.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mex:Mext_4488 pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 5286150 7114948 Mchl_4951 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002423644.1 5285230 R 440085 CDS YP_002423645.1 218532829 7114949 complement(5286147..5286773) 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_4489 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 5286773 7114949 Mchl_4952 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002423645.1 5286147 R 440085 CDS YP_002423646.1 218532830 7114950 5286918..5287823 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4490 LysR substrate-binding; LysR family transcriptional regulator 5287823 7114950 Mchl_4953 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423646.1 5286918 D 440085 CDS YP_002423647.1 218532831 7114951 complement(5287853..5289457) 1 NC_011757.1 Catalyzes the reduction of sulfite to sulfide, an essential step in the anaerobic sulfate-respiration pathway; sulfite reductase 5289457 7114951 Mchl_4954 Methylobacterium extorquens CM4 sulfite reductase YP_002423647.1 5287853 R 440085 CDS YP_002423648.1 218532832 7114952 complement(5289454..5291244) 1 NC_011757.1 ferredoxin-dependent assimilatory nitrite reductase; ferredoxin-nitrite reductase 5291244 nirA 7114952 nirA Methylobacterium extorquens CM4 ferredoxin-nitrite reductase YP_002423648.1 5289454 R 440085 CDS YP_002423649.1 218532833 7114953 complement(5291256..5292476) 1 NC_011757.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: mex:Mext_4493 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5292476 7114953 Mchl_4956 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002423649.1 5291256 R 440085 CDS YP_002423650.1 218532834 7114954 complement(5292502..5293296) 1 NC_011757.1 KEGG: mex:Mext_4494 nitrate ABC transporter ATPase subunits C and D; TIGRFAM: nitrate ABC transporter ATPases C and D; PFAM: ABC transporter; SMART: ATPase AAA; nitrate ABC transporter ATPases C and D 5293296 7114954 Mchl_4957 Methylobacterium extorquens CM4 nitrate ABC transporter ATPases C and D YP_002423650.1 5292502 R 440085 CDS YP_002423651.1 218532835 7114955 complement(5293309..5294166) 1 NC_011757.1 TIGRFAM: nitrate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4495 nitrate ABC transporter inner membrane subunit; nitrate ABC transporter inner membrane subunit 5294166 7114955 Mchl_4958 Methylobacterium extorquens CM4 nitrate ABC transporter inner membrane subunit YP_002423651.1 5293309 R 440085 CDS YP_002423652.1 218532836 7114956 complement(5294166..5295458) 1 NC_011757.1 KEGG: mex:Mext_4496 twin-arginine translocation pathway signal; twin-arginine translocation pathway signal 5295458 7114956 Mchl_4959 Methylobacterium extorquens CM4 twin-arginine translocation pathway signal YP_002423652.1 5294166 R 440085 CDS YP_002423653.1 218532837 7114957 complement(5295787..5296803) 1 NC_011757.1 KEGG: mex:Mext_4497 nitrate transporter; nitrate transporter 5296803 7114957 Mchl_4960 Methylobacterium extorquens CM4 nitrate transporter YP_002423653.1 5295787 R 440085 CDS YP_002423654.1 218532838 7114958 complement(5296800..5297387) 1 NC_011757.1 PFAM: response regulator receiver; ANTAR domain protein; KEGG: mex:Mext_4498 ANTAR domain-containing protein; response regulator receiver and ANTAR domain-containing protein 5297387 7114958 Mchl_4961 Methylobacterium extorquens CM4 response regulator receiver and ANTAR domain-containing protein YP_002423654.1 5296800 R 440085 CDS YP_002423655.1 218532839 7114959 5297640..5298260 1 NC_011757.1 KEGG: mex:Mext_4499 hypothetical protein; hypothetical protein 5298260 7114959 Mchl_4962 Methylobacterium extorquens CM4 hypothetical protein YP_002423655.1 5297640 D 440085 CDS YP_002423656.1 218532840 7114960 5298482..5300341 1 NC_011757.1 PFAM: glycoside hydrolase 15-related; KEGG: mex:Mext_4500 glycoside hydrolase 15-related; glycoside hydrolase 15-like protein 5300341 7114960 Mchl_4963 Methylobacterium extorquens CM4 glycoside hydrolase 15-like protein YP_002423656.1 5298482 D 440085 CDS YP_002423657.1 218532841 7114961 5300392..5302467 1 NC_011757.1 TIGRFAM: transketolase; PFAM: transketolase domain protein; transketolase; KEGG: mex:Mext_4501 transketolase; transketolase 5302467 7114961 Mchl_4964 Methylobacterium extorquens CM4 transketolase YP_002423657.1 5300392 D 440085 CDS YP_002423658.1 218532842 7114962 5302687..5305512 1 NC_011757.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; catalyzes isomerization of glucose 6-phosphate and fructose 6-phosphate; bifunctional transaldolase/phosoglucose isomerase 5305512 7114962 Mchl_4965 Methylobacterium extorquens CM4 bifunctional transaldolase/phosoglucose isomerase YP_002423658.1 5302687 D 440085 CDS YP_002423659.1 218532843 7114963 complement(5305811..5306455) 1 NC_011757.1 PFAM: hypothetical protein; KEGG: mex:Mext_4503 hypothetical protein; hypothetical protein 5306455 7114963 Mchl_4966 Methylobacterium extorquens CM4 hypothetical protein YP_002423659.1 5305811 R 440085 CDS YP_002423660.1 218532844 7114964 complement(5306552..5306821) 1 NC_011757.1 KEGG: mex:Mext_4504 hypothetical protein; hypothetical protein 5306821 7114964 Mchl_4967 Methylobacterium extorquens CM4 hypothetical protein YP_002423660.1 5306552 R 440085 CDS YP_002423661.1 218532845 7114965 complement(5306890..5308350) 1 NC_011757.1 KEGG: mex:Mext_4505 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 5308350 7114965 Mchl_4968 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor YP_002423661.1 5306890 R 440085 CDS YP_002423662.1 218532846 7114966 complement(5308773..5309645) 1 NC_011757.1 KEGG: mex:Mext_4506 hypothetical protein; hypothetical protein 5309645 7114966 Mchl_4969 Methylobacterium extorquens CM4 hypothetical protein YP_002423662.1 5308773 R 440085 CDS YP_002423663.1 218532847 7114967 complement(5309829..5310863) 1 NC_011757.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4507 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5310863 7114967 Mchl_4970 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423663.1 5309829 R 440085 CDS YP_002423664.1 218532848 7114968 complement(5311030..5314239) 1 NC_011757.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_4508 hydrophobe/amphiphile efflux-1 (HAE1) family protein; hydrophobe/amphiphile efflux-1 (HAE1) family transporter 5314239 7114968 Mchl_4971 Methylobacterium extorquens CM4 hydrophobe/amphiphile efflux-1 (HAE1) family transporter YP_002423664.1 5311030 R 440085 CDS YP_002423665.1 218532849 7114969 complement(5314402..5315547) 1 NC_011757.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mex:Mext_4509 RND family efflux transporter MFP subunit; efflux transporter RND family MFP subunit 5315547 7114969 Mchl_4972 Methylobacterium extorquens CM4 efflux transporter RND family MFP subunit YP_002423665.1 5314402 R 440085 CDS YP_002423666.1 218532850 7114970 complement(5315667..5315990) 1 NC_011757.1 PFAM: rhodanese; KEGG: mex:Mext_4510 rhodanese; rhodanese 5315990 7114970 Mchl_4973 Methylobacterium extorquens CM4 rhodanese YP_002423666.1 5315667 R 440085 CDS YP_002423667.1 218532851 7114971 complement(5316039..5317409) 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_4511 glycosyl transferase group 1; group 1 glycosyl transferase 5317409 7114971 Mchl_4974 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002423667.1 5316039 R 440085 CDS YP_002423668.1 218532852 7114972 complement(5317474..5318022) 1 NC_011757.1 KEGG: mex:Mext_4512 hypothetical protein; hypothetical protein 5318022 7114972 Mchl_4975 Methylobacterium extorquens CM4 hypothetical protein YP_002423668.1 5317474 R 440085 CDS YP_002423669.1 218532853 7114973 complement(5318195..5318830) 1 NC_011757.1 PFAM: autoinducer synthesis protein; KEGG: mex:Mext_4513 autoinducer synthesis protein; autoinducer synthesis protein 5318830 7114973 Mchl_4976 Methylobacterium extorquens CM4 autoinducer synthesis protein YP_002423669.1 5318195 R 440085 CDS YP_002423670.1 218532854 7114974 complement(5319310..5320041) 1 NC_011757.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: mex:Mext_4514 autoinducer-binding domain-containing protein; LuxR family transcriptional regulator 5320041 7114974 Mchl_4977 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002423670.1 5319310 R 440085 CDS YP_002423671.1 218532855 7114976 complement(5320604..5321563) 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4518 LysR substrate-binding; LysR family transcriptional regulator 5321563 7114976 Mchl_4978 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423671.1 5320604 R 440085 CDS YP_002423672.1 218532856 7114977 5321660..5321911 1 NC_011757.1 KEGG: mex:Mext_4519 hypothetical protein; hypothetical protein 5321911 7114977 Mchl_4979 Methylobacterium extorquens CM4 hypothetical protein YP_002423672.1 5321660 D 440085 CDS YP_002423673.1 218532857 7114978 complement(5322054..5325248) 1 NC_011757.1 PFAM: acriflavin resistance protein; KEGG: mex:Mext_4520 acriflavin resistance protein; acriflavin resistance protein 5325248 7114978 Mchl_4980 Methylobacterium extorquens CM4 acriflavin resistance protein YP_002423673.1 5322054 R 440085 CDS YP_002423674.1 218532858 7114979 complement(5325251..5326357) 1 NC_011757.1 KEGG: mex:Mext_4521 hypothetical protein; hypothetical protein 5326357 7114979 Mchl_4981 Methylobacterium extorquens CM4 hypothetical protein YP_002423674.1 5325251 R 440085 CDS YP_002423675.1 218532859 7114980 5326594..5327007 1 NC_011757.1 KEGG: mex:Mext_4522 hypothetical protein; hypothetical protein 5327007 7114980 Mchl_4982 Methylobacterium extorquens CM4 hypothetical protein YP_002423675.1 5326594 D 440085 CDS YP_002423676.1 218532860 7114981 5327108..5327629 1 NC_011757.1 KEGG: mex:Mext_4523 hypothetical protein; hypothetical protein 5327629 7114981 Mchl_4983 Methylobacterium extorquens CM4 hypothetical protein YP_002423676.1 5327108 D 440085 CDS YP_002423677.1 218532861 7114982 complement(5327642..5329480) 1 NC_011757.1 PFAM: pyrrolo-quinoline quinone; KEGG: mex:Mext_4524 pyrrolo-quinoline quinone; pyrrolo-quinoline quinone 5329480 7114982 Mchl_4984 Methylobacterium extorquens CM4 pyrrolo-quinoline quinone YP_002423677.1 5327642 R 440085 CDS YP_002423678.1 218532862 7114983 5329671..5329943 1 NC_011757.1 KEGG: mex:Mext_4525 hypothetical protein; hypothetical protein 5329943 7114983 Mchl_4985 Methylobacterium extorquens CM4 hypothetical protein YP_002423678.1 5329671 D 440085 CDS YP_002423679.1 218532863 7114984 complement(5329988..5331133) 1 NC_011757.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: mex:Mext_4526 histidine kinase dimerisation/phosphoacceptor; signal transduction histidine kinase 5331133 7114984 Mchl_4986 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002423679.1 5329988 R 440085 CDS YP_002423680.1 218532864 7114985 complement(5331334..5331720) 1 NC_011757.1 KEGG: mex:Mext_4527 hypothetical protein; hypothetical protein 5331720 7114985 Mchl_4987 Methylobacterium extorquens CM4 hypothetical protein YP_002423680.1 5331334 R 440085 CDS YP_002423681.1 218532865 7114986 complement(5331862..5334213) 1 NC_011757.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_4528 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 5334213 7114986 Mchl_4988 Methylobacterium extorquens CM4 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_002423681.1 5331862 R 440085 CDS YP_002423682.1 218532866 7114987 complement(5334210..5334695) 1 NC_011757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_4529 2Fe-2S iron-sulfur cluster binding domain-containing protein; (2Fe-2S)-binding domain-containing protein 5334695 7114987 Mchl_4989 Methylobacterium extorquens CM4 (2Fe-2S)-binding domain-containing protein YP_002423682.1 5334210 R 440085 CDS YP_002423683.1 218532867 7114988 complement(5335112..5335456) 1 NC_011757.1 KEGG: mex:Mext_4530 hypothetical protein; hypothetical protein 5335456 7114988 Mchl_4990 Methylobacterium extorquens CM4 hypothetical protein YP_002423683.1 5335112 R 440085 CDS YP_002423684.1 218532868 7114989 complement(5335712..5335909) 1 NC_011757.1 KEGG: mex:Mext_4531 hypothetical protein; hypothetical protein 5335909 7114989 Mchl_4991 Methylobacterium extorquens CM4 hypothetical protein YP_002423684.1 5335712 R 440085 CDS YP_002423685.1 218532869 7114990 5336256..5336501 1 NC_011757.1 KEGG: mex:Mext_4532 hypothetical protein; hypothetical protein 5336501 7114990 Mchl_4992 Methylobacterium extorquens CM4 hypothetical protein YP_002423685.1 5336256 D 440085 CDS YP_002423686.1 218532870 7114991 complement(5336663..5339611) 1 NC_011757.1 KEGG: mex:Mext_4533 phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 5339611 7114991 Mchl_4993 Methylobacterium extorquens CM4 phosphoenolpyruvate carboxylase YP_002423686.1 5336663 R 440085 CDS YP_002423687.1 218532871 7114992 5339738..5340304 1 NC_011757.1 KEGG: mex:Mext_4534 hypothetical protein; hypothetical protein 5340304 7114992 Mchl_4994 Methylobacterium extorquens CM4 hypothetical protein YP_002423687.1 5339738 D 440085 CDS YP_002423688.1 218532872 7114993 5340301..5341173 1 NC_011757.1 KEGG: mex:Mext_4535 hypothetical protein; hypothetical protein 5341173 7114993 Mchl_4995 Methylobacterium extorquens CM4 hypothetical protein YP_002423688.1 5340301 D 440085 CDS YP_002423689.1 218532873 7114994 5341191..5342855 1 NC_011757.1 PFAM: saccharopine dehydrogenase; KEGG: mex:Mext_4536 saccharopine dehydrogenase; saccharopine dehydrogenase 5342855 7114994 Mchl_4996 Methylobacterium extorquens CM4 saccharopine dehydrogenase YP_002423689.1 5341191 D 440085 CDS YP_002423690.1 218532874 7114995 5342852..5343292 1 NC_011757.1 PFAM: protein of unknown function DUF985; KEGG: mex:Mext_4537 hypothetical protein; hypothetical protein 5343292 7114995 Mchl_4997 Methylobacterium extorquens CM4 hypothetical protein YP_002423690.1 5342852 D 440085 CDS YP_002423691.1 218532875 7114996 5343427..5344644 1 NC_011757.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: mex:Mext_4538 oxidoreductase domain-containing protein; oxidoreductase domain-containing protein 5344644 7114996 Mchl_4998 Methylobacterium extorquens CM4 oxidoreductase domain-containing protein YP_002423691.1 5343427 D 440085 CDS YP_002423692.1 218532876 7114997 5344743..5345186 1 NC_011757.1 PFAM: protein of unknown function DUF606; KEGG: mex:Mext_4539 hypothetical protein; hypothetical protein 5345186 7114997 Mchl_4999 Methylobacterium extorquens CM4 hypothetical protein YP_002423692.1 5344743 D 440085 CDS YP_002423693.1 218532877 7114998 5345519..5346406 1 NC_011757.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mex:Mext_4540 LysR substrate-binding; LysR family transcriptional regulator 5346406 7114998 Mchl_5000 Methylobacterium extorquens CM4 LysR family transcriptional regulator YP_002423693.1 5345519 D 440085 CDS YP_002423694.1 218532878 7114999 complement(5346412..5347434) 1 NC_011757.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_4541 alcohol dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 5347434 7114999 Mchl_5001 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain-containing protein YP_002423694.1 5346412 R 440085 CDS YP_002423695.1 218532879 7115000 5347715..5351005 1 NC_011757.1 KEGG: mex:Mext_4542 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; hypothetical protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; signal transduction histidine kinase 5351005 7115000 Mchl_5002 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002423695.1 5347715 D 440085 CDS YP_002423696.1 218532880 7115001 complement(5351073..5351357) 1 NC_011757.1 PFAM: SH3 type 3 domain protein; KEGG: mex:Mext_4543 SH3 type 3 domain-containing protein; SH3 type 3 domain-containing protein 5351357 7115001 Mchl_5003 Methylobacterium extorquens CM4 SH3 type 3 domain-containing protein YP_002423696.1 5351073 R 440085 CDS YP_002423697.1 218532881 7115002 complement(5351369..5352142) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4544 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5352142 7115002 Mchl_5004 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423697.1 5351369 R 440085 CDS YP_002423698.1 218532882 7115003 complement(5352139..5353425) 1 NC_011757.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-(acyl carrier protein) synthase II 5353425 7115003 Mchl_5005 Methylobacterium extorquens CM4 3-oxoacyl-(acyl carrier protein) synthase II YP_002423698.1 5352139 R 440085 CDS YP_002423699.1 218532883 7115004 complement(5353556..5354716) 1 NC_011757.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 5354716 7115004 Mchl_5006 Methylobacterium extorquens CM4 3-oxoacyl-(acyl carrier protein) synthase II YP_002423699.1 5353556 R 440085 CDS YP_002423700.1 218532884 7115005 complement(5354713..5355177) 1 NC_011757.1 PFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: mex:Mext_4547 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ 5355177 7115005 Mchl_5007 Methylobacterium extorquens CM4 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ YP_002423700.1 5354713 R 440085 CDS YP_002423701.1 218532885 7115006 complement(5355206..5355502) 1 NC_011757.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein 5355502 7115006 Mchl_5008 Methylobacterium extorquens CM4 acyl carrier protein YP_002423701.1 5355206 R 440085 CDS YP_002423702.1 218532886 7115007 complement(5355708..5356196) 1 NC_011757.1 KEGG: mex:Mext_4549 hypothetical protein; hypothetical protein 5356196 7115007 Mchl_5009 Methylobacterium extorquens CM4 hypothetical protein YP_002423702.1 5355708 R 440085 CDS YP_002423703.1 218532887 7115008 5356381..5356680 1 NC_011757.1 KEGG: mex:Mext_4550 GGDEF family protein; response regulator receiver protein 5356680 7115008 Mchl_5010 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423703.1 5356381 D 440085 CDS YP_002423704.1 218532888 7115009 5356757..5357836 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_4551 hypothetical protein; hypothetical protein 5357836 7115009 Mchl_5011 Methylobacterium extorquens CM4 hypothetical protein YP_002423704.1 5356757 D 440085 CDS YP_002423705.1 218532889 7115010 complement(5357841..5358710) 1 NC_011757.1 KEGG: mex:Mext_4552 hypothetical protein; hypothetical protein 5358710 7115010 Mchl_5012 Methylobacterium extorquens CM4 hypothetical protein YP_002423705.1 5357841 R 440085 CDS YP_002423706.1 218532890 7115011 5358940..5359374 1 NC_011757.1 KEGG: mex:Mext_4553 hypothetical protein; hypothetical protein 5359374 7115011 Mchl_5013 Methylobacterium extorquens CM4 hypothetical protein YP_002423706.1 5358940 D 440085 CDS YP_002423707.1 218532891 7115012 5359379..5359792 1 NC_011757.1 PFAM: cupin; KEGG: mex:Mext_4554 cupin 2 domain-containing protein; cupin 5359792 7115012 Mchl_5014 Methylobacterium extorquens CM4 cupin YP_002423707.1 5359379 D 440085 CDS YP_002423708.1 218532892 7115013 5359838..5360134 1 NC_011757.1 KEGG: mex:Mext_4555 hypothetical protein; hypothetical protein 5360134 7115013 Mchl_5015 Methylobacterium extorquens CM4 hypothetical protein YP_002423708.1 5359838 D 440085 CDS YP_002423709.1 218532893 7115014 complement(5360209..5360679) 1 NC_011757.1 PFAM: heat shock protein Hsp20; KEGG: mex:Mext_4556 heat shock protein HSP20; heat shock protein Hsp20 5360679 7115014 Mchl_5016 Methylobacterium extorquens CM4 heat shock protein Hsp20 YP_002423709.1 5360209 R 440085 CDS YP_002423710.1 218532894 7115015 5360862..5361854 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_4557 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 5361854 7115015 Mchl_5017 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002423710.1 5360862 D 440085 CDS YP_002423711.1 218532895 7115016 5362561..5364852 1 NC_011757.1 PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_4558 hemolysin-type calcium-binding region; hemolysin-type calcium-binding region 5364852 7115016 Mchl_5018 Methylobacterium extorquens CM4 hemolysin-type calcium-binding region YP_002423711.1 5362561 D 440085 CDS YP_002423712.1 218532896 7115017 complement(5365016..5365807) 1 NC_011757.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: mex:Mext_4559 histidinol-phosphate phosphatase; histidinol-phosphate phosphatase 5365807 7115017 Mchl_5019 Methylobacterium extorquens CM4 histidinol-phosphate phosphatase YP_002423712.1 5365016 R 440085 CDS YP_002423713.1 218532897 7115018 complement(5365863..5367902) 1 NC_011757.1 PFAM: protein of unknown function UPF0118; KEGG: mex:Mext_4560 hypothetical protein; hypothetical protein 5367902 7115018 Mchl_5020 Methylobacterium extorquens CM4 hypothetical protein YP_002423713.1 5365863 R 440085 CDS YP_002423714.1 218532898 7113624 complement(5368132..5368914) 1 NC_011757.1 PFAM: LamB/YcsF family protein; KEGG: mex:Mext_4561 LamB/YcsF family protein; LamB/YcsF family protein 5368914 7113624 Mchl_5021 Methylobacterium extorquens CM4 LamB/YcsF family protein YP_002423714.1 5368132 R 440085 CDS YP_002423715.1 218532899 7113625 complement(5368925..5370223) 1 NC_011757.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 5370223 7113625 Mchl_5022 Methylobacterium extorquens CM4 nicotinate phosphoribosyltransferase YP_002423715.1 5368925 R 440085 CDS YP_002423716.1 218532900 7113626 complement(5370383..5370886) 1 NC_011757.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mex:Mext_4563 pyridoxamine 5'-phosphate oxidase-related FMN-binding; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 5370886 7113626 Mchl_5023 Methylobacterium extorquens CM4 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002423716.1 5370383 R 440085 CDS YP_002423717.1 218532901 7113627 5371054..5371326 1 NC_011757.1 KEGG: mex:Mext_4564 hypothetical protein; hypothetical protein 5371326 7113627 Mchl_5024 Methylobacterium extorquens CM4 hypothetical protein YP_002423717.1 5371054 D 440085 CDS YP_002423718.1 218532902 7113628 5371418..5372545 1 NC_011757.1 PFAM: Mrp protein; KEGG: mex:Mext_4565 MRP protein-like protein; Mrp protein 5372545 7113628 Mchl_5025 Methylobacterium extorquens CM4 Mrp protein YP_002423718.1 5371418 D 440085 CDS YP_002423719.1 218532903 7113629 5372542..5373198 1 NC_011757.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: mex:Mext_4566 molybdopterin-guanine dinucleotide biosynthesis protein A; molybdopterin-guanine dinucleotide biosynthesis protein A 5373198 7113629 Mchl_5026 Methylobacterium extorquens CM4 molybdopterin-guanine dinucleotide biosynthesis protein A YP_002423719.1 5372542 D 440085 CDS YP_002423720.1 218532904 7113630 5373526..5376261 1 NC_011757.1 TIGRFAM: DNA gyrase subunit alpha; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; KEGG: mex:Mext_4567 DNA gyrase subunit alpha; DNA gyrase subunit alpha 5376261 7113630 Mchl_5027 Methylobacterium extorquens CM4 DNA gyrase subunit alpha YP_002423720.1 5373526 D 440085 CDS YP_002423721.1 218532905 7113631 5376483..5377307 1 NC_011757.1 KEGG: mex:Mext_4568 porin; porin 5377307 7113631 Mchl_5028 Methylobacterium extorquens CM4 porin YP_002423721.1 5376483 D 440085 CDS YP_002423722.1 218532906 7113632 5377451..5377954 1 NC_011757.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 5377954 coaD 7113632 coaD Methylobacterium extorquens CM4 phosphopantetheine adenylyltransferase YP_002423722.1 5377451 D 440085 CDS YP_002423723.1 218532907 7113633 5377996..5378538 1 NC_011757.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: mex:Mext_4570 peptidyl-prolyl cis-trans isomerase cyclophilin type; cyclophilin type peptidyl-prolyl cis-trans isomerase 5378538 7113633 Mchl_5030 Methylobacterium extorquens CM4 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_002423723.1 5377996 D 440085 CDS YP_002423724.1 218532908 7113634 5378598..5379044 1 NC_011757.1 KEGG: mex:Mext_4571 hypothetical protein; hypothetical protein 5379044 7113634 Mchl_5031 Methylobacterium extorquens CM4 hypothetical protein YP_002423724.1 5378598 D 440085 CDS YP_002423725.1 218532909 7113635 5379048..5379509 1 NC_011757.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: mex:Mext_4572 peptidyl-prolyl cis-trans isomerase cyclophilin type; cyclophilin type peptidyl-prolyl cis-trans isomerase 5379509 7113635 Mchl_5032 Methylobacterium extorquens CM4 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_002423725.1 5379048 D 440085 CDS YP_002423726.1 218532910 7113636 complement(5379579..5379983) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4573 response regulator receiver; response regulator receiver protein 5379983 7113636 Mchl_5033 Methylobacterium extorquens CM4 response regulator receiver protein YP_002423726.1 5379579 R 440085 CDS YP_002423727.1 218532911 7113637 5380376..5381137 1 NC_011757.1 KEGG: mex:Mext_4574 hypothetical protein; hypothetical protein 5381137 7113637 Mchl_5034 Methylobacterium extorquens CM4 hypothetical protein YP_002423727.1 5380376 D 440085 CDS YP_002423728.1 218532912 7113638 5381151..5382554 1 NC_011757.1 KEGG: mex:Mext_4575 hypothetical protein; hypothetical protein 5382554 7113638 Mchl_5035 Methylobacterium extorquens CM4 hypothetical protein YP_002423728.1 5381151 D 440085 CDS YP_002423729.1 218532913 7113639 5382631..5385846 1 NC_011757.1 KEGG: mex:Mext_4576 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III subunit alpha; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein; DNA polymerase III subunit alpha 5385846 7113639 Mchl_5036 Methylobacterium extorquens CM4 DNA polymerase III subunit alpha YP_002423729.1 5382631 D 440085 CDS YP_002423730.1 218532914 7113640 5386000..5386212 1 NC_011757.1 KEGG: mex:Mext_4577 hypothetical protein; hypothetical protein 5386212 7113640 Mchl_5037 Methylobacterium extorquens CM4 hypothetical protein YP_002423730.1 5386000 D 440085 CDS YP_002423731.1 218532915 7113641 5386438..5387463 1 NC_011757.1 PFAM: patatin; KEGG: mex:Mext_4578 patatin; patatin 5387463 7113641 Mchl_5038 Methylobacterium extorquens CM4 patatin YP_002423731.1 5386438 D 440085 CDS YP_002423732.1 218532916 7113642 complement(5387628..5388398) 1 NC_011757.1 PFAM: ion transporter; ion transport 2 domain protein; KEGG: mex:Mext_4579 ion transport 2 domain-containing protein; ion transport 2 domain-containing protein 5388398 7113642 Mchl_5039 Methylobacterium extorquens CM4 ion transport 2 domain-containing protein YP_002423732.1 5387628 R 440085 CDS YP_002423733.1 218532917 7113643 complement(5388426..5388566) 1 NC_011757.1 hypothetical protein 5388566 7113643 Mchl_5040 Methylobacterium extorquens CM4 hypothetical protein YP_002423733.1 5388426 R 440085 CDS YP_002423734.1 218532918 7113644 5388914..5389219 1 NC_011757.1 KEGG: mex:Mext_4580 hypothetical protein; hypothetical protein 5389219 7113644 Mchl_5041 Methylobacterium extorquens CM4 hypothetical protein YP_002423734.1 5388914 D 440085 CDS YP_002423735.1 218532919 7113645 5389283..5391001 1 NC_011757.1 PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mex:Mext_4581 respiratory-chain NADH dehydrogenase domain-containing protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit 5391001 7113645 Mchl_5042 Methylobacterium extorquens CM4 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit YP_002423735.1 5389283 D 440085 CDS YP_002423736.1 218532920 7113646 5391054..5394023 1 NC_011757.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mex:Mext_4582 formate dehydrogenase, subunit alpha; formate dehydrogenase subunit alpha 5394023 7113646 Mchl_5043 Methylobacterium extorquens CM4 formate dehydrogenase subunit alpha YP_002423736.1 5391054 D 440085 CDS YP_002423737.1 218532921 7113647 complement(5394282..5395634) 1 NC_011757.1 PFAM: polysaccharide biosynthesis protein; KEGG: mex:Mext_4583 polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 5395634 7113647 Mchl_5044 Methylobacterium extorquens CM4 polysaccharide biosynthesis protein YP_002423737.1 5394282 R 440085 CDS YP_002423738.1 218532922 7113648 complement(5395649..5396647) 1 NC_011757.1 KEGG: mex:Mext_4584 hypothetical protein; hypothetical protein 5396647 7113648 Mchl_5045 Methylobacterium extorquens CM4 hypothetical protein YP_002423738.1 5395649 R 440085 CDS YP_002423739.1 218532923 7113649 5396852..5397682 1 NC_011757.1 PFAM: polysaccharide deacetylase; KEGG: mex:Mext_4585 polysaccharide deacetylase; polysaccharide deacetylase 5397682 7113649 Mchl_5046 Methylobacterium extorquens CM4 polysaccharide deacetylase YP_002423739.1 5396852 D 440085 CDS YP_002423740.1 218532924 7113650 5397820..5398950 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_4586 glycosyl transferase group 1; group 1 glycosyl transferase 5398950 7113650 Mchl_5047 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002423740.1 5397820 D 440085 CDS YP_002423741.1 218532925 7113651 5399381..5399899 1 NC_011757.1 KEGG: mex:Mext_4587 hypothetical protein; hypothetical protein 5399899 7113651 Mchl_5048 Methylobacterium extorquens CM4 hypothetical protein YP_002423741.1 5399381 D 440085 CDS YP_002423742.1 218532926 7118840 complement(5400013..5402052) 1 NC_011757.1 KEGG: mex:Mext_4588 hypothetical protein; hypothetical protein 5402052 7118840 Mchl_5049 Methylobacterium extorquens CM4 hypothetical protein YP_002423742.1 5400013 R 440085 CDS YP_002423743.1 218532927 7118924 complement(5402049..5404172) 1 NC_011757.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: mex:Mext_4589 lipopolysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 5404172 7118924 Mchl_5050 Methylobacterium extorquens CM4 lipopolysaccharide biosynthesis protein YP_002423743.1 5402049 R 440085 CDS YP_002423744.1 218532928 7118925 complement(5404351..5405721) 1 NC_011757.1 KEGG: mex:Mext_4590 hypothetical protein; hypothetical protein 5405721 7118925 Mchl_5051 Methylobacterium extorquens CM4 hypothetical protein YP_002423744.1 5404351 R 440085 CDS YP_002423745.1 218532929 7118926 complement(5406063..5407007) 1 NC_011757.1 KEGG: mex:Mext_4591 hypothetical protein; hypothetical protein 5407007 7118926 Mchl_5052 Methylobacterium extorquens CM4 hypothetical protein YP_002423745.1 5406063 R 440085 CDS YP_002423746.1 218532930 7118927 complement(5407283..5408026) 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4592 short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 5408026 7118927 Mchl_5053 Methylobacterium extorquens CM4 short-chain dehydrogenase/reductase SDR YP_002423746.1 5407283 R 440085 CDS YP_002423747.1 218532931 7118928 complement(5408023..5409384) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_4593 AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase 5409384 7118928 Mchl_5054 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002423747.1 5408023 R 440085 CDS YP_002423748.1 218532932 7118929 complement(5409390..5409647) 1 NC_011757.1 KEGG: mex:Mext_4594 acyl carrier protein; acyl carrier protein 5409647 7118929 Mchl_5055 Methylobacterium extorquens CM4 acyl carrier protein YP_002423748.1 5409390 R 440085 CDS YP_002423749.1 218532933 7118930 complement(5409698..5410615) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: mex:Mext_4595 alpha/beta hydrolase domain-containing protein; alpha/beta hydrolase fold-3 domain-containing protein 5410615 7118930 Mchl_5056 Methylobacterium extorquens CM4 alpha/beta hydrolase fold-3 domain-containing protein YP_002423749.1 5409698 R 440085 CDS YP_002423750.1 218532934 7118931 complement(5410633..5411565) 1 NC_011757.1 KEGG: mex:Mext_4596 hypothetical protein; hypothetical protein 5411565 7118931 Mchl_5057 Methylobacterium extorquens CM4 hypothetical protein YP_002423750.1 5410633 R 440085 CDS YP_002423751.1 218532935 7118932 complement(5411739..5412941) 1 NC_011757.1 PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_4597 acyl-CoA dehydrogenase domain-containing protein; acyl-CoA dehydrogenase domain-containing protein 5412941 7118932 Mchl_5058 Methylobacterium extorquens CM4 acyl-CoA dehydrogenase domain-containing protein YP_002423751.1 5411739 R 440085 CDS YP_002423752.1 218532936 7118933 complement(5413037..5413306) 1 NC_011757.1 KEGG: mex:Mext_4598 hypothetical protein; hypothetical protein 5413306 7118933 Mchl_5059 Methylobacterium extorquens CM4 hypothetical protein YP_002423752.1 5413037 R 440085 CDS YP_002423753.1 218532937 7118934 complement(5413440..5414012) 1 NC_011757.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: mex:Mext_4599 flavin reductase domain-containing protein; flavin reductase domain-containing FMN-binding protein 5414012 7118934 Mchl_5060 Methylobacterium extorquens CM4 flavin reductase domain-containing FMN-binding protein YP_002423753.1 5413440 R 440085 CDS YP_002423754.1 218532938 7118935 5414322..5416025 1 NC_011757.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mex:Mext_4600 acetolactate synthase 2 catalytic subunit; thiamine pyrophosphate protein 5416025 7118935 Mchl_5061 Methylobacterium extorquens CM4 thiamine pyrophosphate protein YP_002423754.1 5414322 D 440085 CDS YP_002423755.1 218532939 7118936 5416157..5416480 1 NC_011757.1 KEGG: mex:Mext_4601 hypothetical protein; hypothetical protein 5416480 7118936 Mchl_5062 Methylobacterium extorquens CM4 hypothetical protein YP_002423755.1 5416157 D 440085 CDS YP_002423756.1 218532940 7118937 complement(5416525..5417391) 1 NC_011757.1 PFAM: aminotransferase class IV; KEGG: mex:Mext_4602 aminotransferase; aminotransferase 5417391 7118937 Mchl_5063 Methylobacterium extorquens CM4 aminotransferase YP_002423756.1 5416525 R 440085 CDS YP_002423757.1 218532941 7118938 complement(5417418..5417867) 1 NC_011757.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: mex:Mext_4603 protein of unknown function DUF861 cupin_3; hypothetical protein 5417867 7118938 Mchl_5064 Methylobacterium extorquens CM4 hypothetical protein YP_002423757.1 5417418 R 440085 CDS YP_002423758.1 218532942 7118939 5418346..5419638 1 NC_011757.1 KEGG: mex:Mext_4604 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; O-acetylhomoserine/O-acetylserine sulfhydrylase 5419638 7118939 Mchl_5065 Methylobacterium extorquens CM4 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_002423758.1 5418346 D 440085 CDS YP_002423759.1 218532943 7118940 5419672..5420667 1 NC_011757.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5420667 7118940 Mchl_5066 Methylobacterium extorquens CM4 homoserine O-succinyltransferase YP_002423759.1 5419672 D 440085 CDS YP_002423760.1 218532944 7118941 5420679..5422511 1 NC_011757.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase 5422511 7118941 Mchl_5067 Methylobacterium extorquens CM4 long-chain-acyl-CoA synthetase YP_002423760.1 5420679 D 440085 CDS YP_002423761.1 218532945 7118942 complement(5422650..5423969) 1 NC_011757.1 KEGG: mex:Mext_4607 hypothetical protein; hypothetical protein 5423969 7118942 Mchl_5068 Methylobacterium extorquens CM4 hypothetical protein YP_002423761.1 5422650 R 440085 CDS YP_002423762.1 218532946 7118943 5424223..5426559 1 NC_011757.1 KEGG: mex:Mext_4608 hypothetical protein; hypothetical protein 5426559 7118943 Mchl_5069 Methylobacterium extorquens CM4 hypothetical protein YP_002423762.1 5424223 D 440085 CDS YP_002423763.1 218532947 7118944 5426556..5427479 1 NC_011757.1 KEGG: mex:Mext_4609 hypothetical protein; hypothetical protein 5427479 7118944 Mchl_5070 Methylobacterium extorquens CM4 hypothetical protein YP_002423763.1 5426556 D 440085 CDS YP_002423764.1 218532948 7118945 5428098..5429495 1 NC_011757.1 KEGG: acr:Acry_1166 triple helix repeat-containing collagen; triple helix repeat-containing collagen 5429495 7118945 Mchl_5071 Methylobacterium extorquens CM4 triple helix repeat-containing collagen YP_002423764.1 5428098 D 440085 CDS YP_002423765.1 218532949 7118946 5429688..5430359 1 NC_011757.1 KEGG: acr:Acry_0615 glycosyl transferase, group 1; hypothetical protein 5430359 7118946 Mchl_5072 Methylobacterium extorquens CM4 hypothetical protein YP_002423765.1 5429688 D 440085 CDS YP_002423766.1 218532950 7118947 5430627..5431736 1 NC_011757.1 PFAM: glycosyl transferase family 2; KEGG: met:M446_3495 glycosyl transferase; family 2 glycosyl transferase 5431736 7118947 Mchl_5073 Methylobacterium extorquens CM4 family 2 glycosyl transferase YP_002423766.1 5430627 D 440085 CDS YP_002423767.1 218532951 7118949 complement(5432416..5434482) 1 NC_011757.1 PFAM: radical SAM protein; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mex:Mext_4610 radical SAM domain-containing protein; radical SAM protein 5434482 7118949 Mchl_5075 Methylobacterium extorquens CM4 radical SAM protein YP_002423767.1 5432416 R 440085 CDS YP_002423768.1 218532952 7118950 complement(5434606..5434947) 1 NC_011757.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: mex:Mext_4611 monovalent cation/proton antiporter, MnhG/PhaG subunit; monovalent cation/proton antiporter, MnhG/PhaG subunit 5434947 7118950 Mchl_5076 Methylobacterium extorquens CM4 monovalent cation/proton antiporter, MnhG/PhaG subunit YP_002423768.1 5434606 R 440085 CDS YP_002423769.1 218532953 7118951 complement(5434944..5435228) 1 NC_011757.1 PFAM: multiple resistance and pH regulation protein F; KEGG: mex:Mext_4612 multiple resistance and pH regulation protein F; multiple resistance and pH regulation protein F 5435228 7118951 Mchl_5077 Methylobacterium extorquens CM4 multiple resistance and pH regulation protein F YP_002423769.1 5434944 R 440085 CDS YP_002423770.1 218532954 7118952 complement(5435225..5435713) 1 NC_011757.1 PFAM: cation antiporter; KEGG: mex:Mext_4613 cation antiporter; cation antiporter 5435713 7118952 Mchl_5078 Methylobacterium extorquens CM4 cation antiporter YP_002423770.1 5435225 R 440085 CDS YP_002423771.1 218532955 7118953 complement(5435710..5437365) 1 NC_011757.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 5437365 7118953 Mchl_5079 Methylobacterium extorquens CM4 monovalent cation/H+ antiporter subunit D YP_002423771.1 5435710 R 440085 CDS YP_002423772.1 218532956 7118954 complement(5437362..5437730) 1 NC_011757.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 5437730 7118954 Mchl_5080 Methylobacterium extorquens CM4 monovalent cation/H+ antiporter subunit C YP_002423772.1 5437362 R 440085 CDS YP_002423773.1 218532957 7118955 complement(5437730..5440669) 1 NC_011757.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; monovalent cation/H+ antiporter subunit A 5440669 7118955 Mchl_5081 Methylobacterium extorquens CM4 monovalent cation/H+ antiporter subunit A YP_002423773.1 5437730 R 440085 CDS YP_002423774.1 218532958 7118956 complement(5441105..5441326) 1 NC_011757.1 KEGG: mex:Mext_4617 hypothetical protein; hypothetical protein 5441326 7118956 Mchl_5082 Methylobacterium extorquens CM4 hypothetical protein YP_002423774.1 5441105 R 440085 CDS YP_002423775.1 218532959 7118957 5441788..5443125 1 NC_011757.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: mex:Mext_4618 nucleotide sugar dehydrogenase; nucleotide sugar dehydrogenase 5443125 7118957 Mchl_5083 Methylobacterium extorquens CM4 nucleotide sugar dehydrogenase YP_002423775.1 5441788 D 440085 CDS YP_002423776.1 218532960 7118958 5443122..5444093 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mex:Mext_4619 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 5444093 7118958 Mchl_5084 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002423776.1 5443122 D 440085 CDS YP_002423777.1 218532961 7118959 5444104..5445042 1 NC_011757.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: mex:Mext_4620 NAD-dependent epimerase/dehydratase; NAD-dependent epimerase/dehydratase 5445042 7118959 Mchl_5085 Methylobacterium extorquens CM4 NAD-dependent epimerase/dehydratase YP_002423777.1 5444104 D 440085 CDS YP_002423778.1 218532962 7118960 5445035..5445910 1 NC_011757.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: mex:Mext_4621 WecB/TagA/CpsF family glycosyl transferase; WecB/TagA/CpsF family glycosyl transferase 5445910 7118960 Mchl_5086 Methylobacterium extorquens CM4 WecB/TagA/CpsF family glycosyl transferase YP_002423778.1 5445035 D 440085 CDS YP_002423779.1 218532963 7118961 5445922..5447094 1 NC_011757.1 PFAM: glycosyl transferase group 1; KEGG: mex:Mext_4622 glycosyl transferase group 1; group 1 glycosyl transferase 5447094 7118961 Mchl_5087 Methylobacterium extorquens CM4 group 1 glycosyl transferase YP_002423779.1 5445922 D 440085 CDS YP_002423780.1 218532964 7118962 complement(5447259..5447426) 1 NC_011757.1 KEGG: mex:Mext_4623 hypothetical protein; hypothetical protein 5447426 7118962 Mchl_5088 Methylobacterium extorquens CM4 hypothetical protein YP_002423780.1 5447259 R 440085 CDS YP_002423781.1 218532965 7118963 complement(5447542..5450112) 1 NC_011757.1 PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: mex:Mext_4624 aspartate racemase; aspartate racemase 5450112 7118963 Mchl_5089 Methylobacterium extorquens CM4 aspartate racemase YP_002423781.1 5447542 R 440085 CDS YP_002423782.1 218532966 7118964 complement(5450124..5453585) 1 NC_011757.1 TIGRFAM: amino acid adenylation protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: mex:Mext_4625 amino acid adenylation domain-containing protein; amino acid adenylation protein 5453585 7118964 Mchl_5090 Methylobacterium extorquens CM4 amino acid adenylation protein YP_002423782.1 5450124 R 440085 CDS YP_002423783.1 218532967 7118965 complement(5453914..5455134) 1 NC_011757.1 KEGG: mex:Mext_4626 hypothetical protein; hypothetical protein 5455134 7118965 Mchl_5091 Methylobacterium extorquens CM4 hypothetical protein YP_002423783.1 5453914 R 440085 CDS YP_002423784.1 218532968 7118966 complement(5455274..5455804) 1 NC_011757.1 PFAM: phosphoglycerate mutase; KEGG: mex:Mext_4627 phosphoglycerate mutase; phosphohistidine phosphatase SixA 5455804 7118966 Mchl_5092 Methylobacterium extorquens CM4 phosphohistidine phosphatase SixA YP_002423784.1 5455274 R 440085 CDS YP_002423785.1 218532969 7118967 complement(5455801..5456781) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_4628 aldo/keto reductase; aldo/keto reductase 5456781 7118967 Mchl_5093 Methylobacterium extorquens CM4 aldo/keto reductase YP_002423785.1 5455801 R 440085 CDS YP_002423786.1 218532970 7118968 complement(5456840..5457691) 1 NC_011757.1 PFAM: ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mex:Mext_4631 ATPase central domain-containing protein; ATPase AAA 5457691 7118968 Mchl_5094 Methylobacterium extorquens CM4 ATPase AAA YP_002423786.1 5456840 R 440085 CDS YP_002423787.1 218532971 7118969 complement(5457787..5458440) 1 NC_011757.1 KEGG: mex:Mext_4632 hypothetical protein; hypothetical protein 5458440 7118969 Mchl_5095 Methylobacterium extorquens CM4 hypothetical protein YP_002423787.1 5457787 R 440085 CDS YP_002423788.1 218532972 7118970 complement(5458567..5459805) 1 NC_011757.1 KEGG: mex:Mext_4633 hypothetical protein; hypothetical protein 5459805 7118970 Mchl_5096 Methylobacterium extorquens CM4 hypothetical protein YP_002423788.1 5458567 R 440085 CDS YP_002423789.1 218532973 7118971 5460108..5462000 1 NC_011757.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mex:Mext_4634 sodium/hydrogen exchanger; sodium/hydrogen exchanger 5462000 7118971 Mchl_5097 Methylobacterium extorquens CM4 sodium/hydrogen exchanger YP_002423789.1 5460108 D 440085 CDS YP_002423790.1 218532974 7118972 complement(5462035..5463402) 1 NC_011757.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 5463402 murD 7118972 murD Methylobacterium extorquens CM4 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002423790.1 5462035 R 440085 CDS YP_002423791.1 218532975 7118973 complement(5463427..5464509) 1 NC_011757.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 5464509 mraY 7118973 mraY Methylobacterium extorquens CM4 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002423791.1 5463427 R 440085 CDS YP_002423792.1 218532976 7118974 complement(5464615..5466078) 1 NC_011757.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: mex:Mext_4637 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase 5466078 7118974 Mchl_5100 Methylobacterium extorquens CM4 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase YP_002423792.1 5464615 R 440085 CDS YP_002423793.1 218532977 7118975 complement(5466075..5467553) 1 NC_011757.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: mex:Mext_4638 UDP-N-acetylmuramyl-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase 5467553 7118975 Mchl_5101 Methylobacterium extorquens CM4 UDP-N-acetylmuramyl-tripeptide synthetase YP_002423793.1 5466075 R 440085 CDS YP_002423794.1 218532978 7118976 complement(5467613..5469490) 1 NC_011757.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: mex:Mext_4639 peptidoglycan glycosyltransferase; peptidoglycan glycosyltransferase 5469490 7118976 Mchl_5102 Methylobacterium extorquens CM4 peptidoglycan glycosyltransferase YP_002423794.1 5467613 R 440085 CDS YP_002423795.1 218532979 7118977 complement(5469498..5469929) 1 NC_011757.1 KEGG: mex:Mext_4640 hypothetical protein; hypothetical protein 5469929 7118977 Mchl_5103 Methylobacterium extorquens CM4 hypothetical protein YP_002423795.1 5469498 R 440085 CDS YP_002423796.1 218532980 7118978 complement(5469926..5470987) 1 NC_011757.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: mex:Mext_4641 S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW 5470987 mraW 7118978 mraW Methylobacterium extorquens CM4 S-adenosyl-methyltransferase MraW YP_002423796.1 5469926 R 440085 CDS YP_002423797.1 218532981 7118980 complement(5471890..5474334) 1 NC_011757.1 KEGG: mex:Mext_4642 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; NAD-dependent DNA ligase adenylation; SMART: NAD-dependent DNA ligase; DNA ligase, NAD-dependent 5474334 7118980 Mchl_5105 Methylobacterium extorquens CM4 DNA ligase, NAD-dependent YP_002423797.1 5471890 R 440085 CDS YP_002423798.1 218532982 7118981 5474452..5474772 1 NC_011757.1 KEGG: mex:Mext_4643 hypothetical protein; hypothetical protein 5474772 7118981 Mchl_5106 Methylobacterium extorquens CM4 hypothetical protein YP_002423798.1 5474452 D 440085 CDS YP_002423799.1 218532983 7118982 5474816..5475382 1 NC_011757.1 PFAM: protein of unknown function DUF820; KEGG: mex:Mext_4644 hypothetical protein; hypothetical protein 5475382 7118982 Mchl_5107 Methylobacterium extorquens CM4 hypothetical protein YP_002423799.1 5474816 D 440085 CDS YP_002423800.1 218532984 7118983 5475459..5476472 1 NC_011757.1 PFAM: PfkB domain protein; KEGG: mex:Mext_4645 ribokinase-like domain-containing protein; PfkB domain-containing protein 5476472 7118983 Mchl_5108 Methylobacterium extorquens CM4 PfkB domain-containing protein YP_002423800.1 5475459 D 440085 CDS YP_002423801.1 218532985 7118984 complement(5476525..5476947) 1 NC_011757.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: mex:Mext_4646 peptidylprolyl isomerase FKBP-type; FKBP-type peptidylprolyl isomerase 5476947 7118984 Mchl_5109 Methylobacterium extorquens CM4 FKBP-type peptidylprolyl isomerase YP_002423801.1 5476525 R 440085 CDS YP_002423802.1 218532986 7118985 complement(5477015..5477482) 1 NC_011757.1 KEGG: mex:Mext_4647 hypothetical protein; hypothetical protein 5477482 7118985 Mchl_5110 Methylobacterium extorquens CM4 hypothetical protein YP_002423802.1 5477015 R 440085 CDS YP_002423803.1 218532987 7118986 5477823..5479043 1 NC_011757.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: mex:Mext_4648 L-carnitine dehydratase/bile acid-inducible protein F; L-carnitine dehydratase/bile acid-inducible protein F 5479043 7118986 Mchl_5111 Methylobacterium extorquens CM4 L-carnitine dehydratase/bile acid-inducible protein F YP_002423803.1 5477823 D 440085 CDS YP_002423804.1 218532988 7118987 5479067..5479891 1 NC_011757.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 5479891 7118987 Mchl_5112 Methylobacterium extorquens CM4 enoyl-CoA hydratase YP_002423804.1 5479067 D 440085 CDS YP_002423805.1 218532989 7118988 complement(5479923..5480615) 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_4650 regulatory protein GntR HTH; GntR family transcriptional regulator 5480615 7118988 Mchl_5113 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002423805.1 5479923 R 440085 CDS YP_002423806.1 218532990 7118989 5480880..5481923 1 NC_011757.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mex:Mext_4651 aromatic amino acid beta-eliminating lyase/threonine aldolase; aromatic amino acid beta-eliminating lyase/threonine aldolase 5481923 7118989 Mchl_5114 Methylobacterium extorquens CM4 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_002423806.1 5480880 D 440085 CDS YP_002423807.1 218532991 7118990 complement(5482054..5482599) 1 NC_011757.1 KEGG: mex:Mext_4652 hypothetical protein; hypothetical protein 5482599 7118990 Mchl_5115 Methylobacterium extorquens CM4 hypothetical protein YP_002423807.1 5482054 R 440085 CDS YP_002423808.1 218532992 7118991 complement(5482683..5483810) 1 NC_011757.1 PFAM: glutamate--cysteine ligase; KEGG: mex:Mext_4653 glutamate--cysteine ligase; glutamate--cysteine ligase 5483810 7118991 Mchl_5116 Methylobacterium extorquens CM4 glutamate--cysteine ligase YP_002423808.1 5482683 R 440085 CDS YP_002423809.1 218532993 7118992 complement(5483880..5484251) 1 NC_011757.1 KEGG: mex:Mext_4654 hypothetical protein; hypothetical protein 5484251 7118992 Mchl_5117 Methylobacterium extorquens CM4 hypothetical protein YP_002423809.1 5483880 R 440085 CDS YP_002423810.1 218532994 7118993 complement(5484248..5485969) 1 NC_011757.1 PFAM: peptidase S10 serine carboxypeptidase; KEGG: mex:Mext_4655 peptidase S10 serine carboxypeptidase; peptidase S10 serine carboxypeptidase 5485969 7118993 Mchl_5118 Methylobacterium extorquens CM4 peptidase S10 serine carboxypeptidase YP_002423810.1 5484248 R 440085 CDS YP_002423811.1 218532995 7118994 complement(5485975..5486427) 1 NC_011757.1 PFAM: DNA polymerase III chi subunit HolC; KEGG: mex:Mext_4656 DNA polymerase III chi subunit HolC; DNA polymerase III chi subunit HolC 5486427 7118994 Mchl_5119 Methylobacterium extorquens CM4 DNA polymerase III chi subunit HolC YP_002423811.1 5485975 R 440085 CDS YP_002423812.1 218532996 7118995 5486589..5486882 1 NC_011757.1 KEGG: mex:Mext_4657 hypothetical protein; hypothetical protein 5486882 7118995 Mchl_5120 Methylobacterium extorquens CM4 hypothetical protein YP_002423812.1 5486589 D 440085 CDS YP_002423813.1 218532997 7118996 complement(5486961..5488124) 1 NC_011757.1 PFAM: glutathionylspermidine synthase; KEGG: mex:Mext_4658 glutathionylspermidine synthase; glutathionylspermidine synthase 5488124 7118996 Mchl_5121 Methylobacterium extorquens CM4 glutathionylspermidine synthase YP_002423813.1 5486961 R 440085 CDS YP_002423814.1 218532998 7118997 complement(5488124..5488756) 1 NC_011757.1 PFAM: protein of unknown function DUF1190; KEGG: mex:Mext_4659 integral membrane protein-like protein; hypothetical protein 5488756 7118997 Mchl_5122 Methylobacterium extorquens CM4 hypothetical protein YP_002423814.1 5488124 R 440085 CDS YP_002423815.1 218532999 7118998 complement(5488761..5489159) 1 NC_011757.1 PFAM: protein of unknown function DUF350; KEGG: mex:Mext_4660 hypothetical protein; hypothetical protein 5489159 7118998 Mchl_5123 Methylobacterium extorquens CM4 hypothetical protein YP_002423815.1 5488761 R 440085 CDS YP_002423816.1 218533000 7118999 complement(5489177..5490805) 1 NC_011757.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 5490805 pyrG 7118999 pyrG Methylobacterium extorquens CM4 CTP synthetase YP_002423816.1 5489177 R 440085 CDS YP_002423817.1 218533001 7119000 complement(5490998..5491465) 1 NC_011757.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: mex:Mext_4662 preprotein translocase, SecG subunit; preprotein translocase subunit SecG 5491465 7119000 Mchl_5125 Methylobacterium extorquens CM4 preprotein translocase subunit SecG YP_002423817.1 5490998 R 440085 CDS YP_002423818.1 218533002 7119001 5491768..5492049 1 NC_011757.1 KEGG: mex:Mext_4663 hypothetical protein; hypothetical protein 5492049 7119001 Mchl_5126 Methylobacterium extorquens CM4 hypothetical protein YP_002423818.1 5491768 D 440085 CDS YP_002423819.1 218533003 7119002 5492070..5492534 1 NC_011757.1 KEGG: mex:Mext_4664 hypothetical protein; hypothetical protein 5492534 7119002 Mchl_5127 Methylobacterium extorquens CM4 hypothetical protein YP_002423819.1 5492070 D 440085 CDS YP_002423820.1 218533004 7119003 complement(5492559..5492828) 1 NC_011757.1 KEGG: mex:Mext_4665 hypothetical protein; hypothetical protein 5492828 7119003 Mchl_5128 Methylobacterium extorquens CM4 hypothetical protein YP_002423820.1 5492559 R 440085 CDS YP_002423821.1 218533005 7119004 complement(5493067..5493831) 1 NC_011757.1 PFAM: triosephosphate isomerase; KEGG: mex:Mext_4666 triose-phosphate isomerase; triose-phosphate isomerase 5493831 7119004 Mchl_5129 Methylobacterium extorquens CM4 triose-phosphate isomerase YP_002423821.1 5493067 R 440085 CDS YP_002423822.1 218533006 7116168 5494065..5495969 1 NC_011757.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: mex:Mext_4667 PpiC-type peptidyl-prolyl cis-trans isomerase; PpiC-type peptidyl-prolyl cis-trans isomerase 5495969 7116168 Mchl_5130 Methylobacterium extorquens CM4 PpiC-type peptidyl-prolyl cis-trans isomerase YP_002423822.1 5494065 D 440085 CDS YP_002423823.1 218533007 7116169 5495978..5497498 1 NC_011757.1 KEGG: mex:Mext_4668 anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: anthranilate synthase component I domain protein; chorismate binding-like; anthranilate synthase component I 5497498 7116169 Mchl_5131 Methylobacterium extorquens CM4 anthranilate synthase component I YP_002423823.1 5495978 D 440085 CDS YP_002423824.1 218533008 7116170 complement(5497560..5499254) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_4669 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5499254 7116170 Mchl_5132 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423824.1 5497560 R 440085 CDS YP_002423825.1 218533009 7116171 5499531..5500133 1 NC_011757.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_4670 glutamine amidotransferase; glutamine amidotransferase 5500133 7116171 Mchl_5133 Methylobacterium extorquens CM4 glutamine amidotransferase YP_002423825.1 5499531 D 440085 CDS YP_002423826.1 218533010 7116172 5500222..5501235 1 NC_011757.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 5501235 trpD 7116172 trpD Methylobacterium extorquens CM4 anthranilate phosphoribosyltransferase YP_002423826.1 5500222 D 440085 CDS YP_002423827.1 218533011 7116173 5501269..5502126 1 NC_011757.1 PFAM: indole-3-glycerol phosphate synthase; KEGG: mex:Mext_4672 indole-3-glycerol-phosphate synthase; indole-3-glycerol-phosphate synthase 5502126 7116173 Mchl_5135 Methylobacterium extorquens CM4 indole-3-glycerol-phosphate synthase YP_002423827.1 5501269 D 440085 CDS YP_002423828.1 218533012 7116174 5502123..5502608 1 NC_011757.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: mex:Mext_4673 molybdenum cofactor biosynthesis protein C; molybdenum cofactor biosynthesis protein C 5502608 7116174 Mchl_5136 Methylobacterium extorquens CM4 molybdenum cofactor biosynthesis protein C YP_002423828.1 5502123 D 440085 CDS YP_002423829.1 218533013 7116175 5502605..5503831 1 NC_011757.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mex:Mext_4674 molybdenum cofactor synthesis domain-containing protein; molybdenum cofactor synthesis protein 5503831 7116175 Mchl_5137 Methylobacterium extorquens CM4 molybdenum cofactor synthesis protein YP_002423829.1 5502605 D 440085 CDS YP_002423830.1 218533014 7116176 5503925..5504161 1 NC_011757.1 KEGG: mpo:Mpop_5215 RelE-like cytotoxic translational repressor of toxin-antitoxin stability system; RelE-like cytotoxic translational repressor of toxin-antitoxin stability system 5504161 7116176 Mchl_5138 Methylobacterium extorquens CM4 RelE-like cytotoxic translational repressor of toxin-antitoxin stability system YP_002423830.1 5503925 D 440085 CDS YP_002423831.1 218533015 7116177 5504262..5504555 1 NC_011757.1 SMART: helix-turn-helix domain protein; KEGG: mpo:Mpop_5216 XRE family transcriptional regulator; XRE family transcriptional regulator 5504555 7116177 Mchl_5139 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002423831.1 5504262 D 440085 CDS YP_002423832.1 218533016 7116178 5504728..5505189 1 NC_011757.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 5505189 fabZ 7116178 fabZ Methylobacterium extorquens CM4 (3R)-hydroxymyristoyl-ACP dehydratase YP_002423832.1 5504728 D 440085 CDS YP_002423833.1 218533017 7116179 5505195..5506001 1 NC_011757.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 5506001 7116179 Mchl_5141 Methylobacterium extorquens CM4 UDP-N-acetylglucosamine acyltransferase YP_002423833.1 5505195 D 440085 CDS YP_002423834.1 218533018 7116180 5506013..5506861 1 NC_011757.1 PFAM: protein of unknown function DUF1009; KEGG: mex:Mext_4677 hypothetical protein; hypothetical protein 5506861 7116180 Mchl_5142 Methylobacterium extorquens CM4 hypothetical protein YP_002423834.1 5506013 D 440085 CDS YP_002423835.1 218533019 7116181 5506858..5508018 1 NC_011757.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 5508018 lpxB 7116181 lpxB Methylobacterium extorquens CM4 lipid-A-disaccharide synthase YP_002423835.1 5506858 D 440085 CDS YP_002423836.1 218533020 7116182 5508015..5508494 1 NC_011757.1 PFAM: protein of unknown function DUF188; KEGG: mex:Mext_4679 hypothetical protein; hypothetical protein 5508494 7116182 Mchl_5144 Methylobacterium extorquens CM4 hypothetical protein YP_002423836.1 5508015 D 440085 CDS YP_002423837.1 218533021 7116183 complement(5508635..5509924) 1 NC_011757.1 KEGG: mex:Mext_4680 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: citrate synthase; citrate synthase I 5509924 7116183 Mchl_5145 Methylobacterium extorquens CM4 citrate synthase I YP_002423837.1 5508635 R 440085 CDS YP_002423838.1 218533022 7116184 complement(5510400..5511824) 1 NC_011757.1 TIGRFAM: glutamyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase class Ic; KEGG: mex:Mext_4681 glutamyl-tRNA synthetase; glutamyl-tRNA synthetase 5511824 7116184 Mchl_5146 Methylobacterium extorquens CM4 glutamyl-tRNA synthetase YP_002423838.1 5510400 R 440085 CDS YP_002423839.1 218533023 7116185 5511992..5514250 1 NC_011757.1 PFAM: ComEC/Rec2-related protein; KEGG: mex:Mext_4682 ComEC/Rec2-related protein; ComEC/Rec2-like protein 5514250 7116185 Mchl_5147 Methylobacterium extorquens CM4 ComEC/Rec2-like protein YP_002423839.1 5511992 D 440085 CDS YP_002423840.1 218533024 7116186 complement(5514244..5514966) 1 NC_011757.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 5514966 7116186 Mchl_5148 Methylobacterium extorquens CM4 LexA repressor YP_002423840.1 5514244 R 440085 CDS YP_002423841.1 218533025 7116187 complement(5515132..5515704) 1 NC_011757.1 PFAM: protein of unknown function DUF1236; KEGG: mex:Mext_4684 hypothetical protein; hypothetical protein 5515704 7116187 Mchl_5149 Methylobacterium extorquens CM4 hypothetical protein YP_002423841.1 5515132 R 440085 CDS YP_002423842.1 218533026 7116188 5516371..5517726 1 NC_011757.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: mex:Mext_4685 general substrate transporter; general substrate transporter 5517726 7116188 Mchl_5150 Methylobacterium extorquens CM4 general substrate transporter YP_002423842.1 5516371 D 440085 CDS YP_002423843.1 218533027 7116189 complement(5517841..5518665) 1 NC_011757.1 PFAM: protein of unknown function DUF849; KEGG: mex:Mext_4686 hypothetical protein; hypothetical protein 5518665 7116189 Mchl_5151 Methylobacterium extorquens CM4 hypothetical protein YP_002423843.1 5517841 R 440085 CDS YP_002423844.1 218533028 7116190 complement(5518679..5519758) 1 NC_011757.1 KEGG: mex:Mext_4687 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase 5519758 7116190 Mchl_5152 Methylobacterium extorquens CM4 tartrate dehydrogenase YP_002423844.1 5518679 R 440085 CDS YP_002423845.1 218533029 7116191 complement(5519898..5520359) 1 NC_011757.1 KEGG: mex:Mext_4688 hypothetical protein; hypothetical protein 5520359 7116191 Mchl_5153 Methylobacterium extorquens CM4 hypothetical protein YP_002423845.1 5519898 R 440085 CDS YP_002423846.1 218533030 7116192 complement(5520470..5521348) 1 NC_011757.1 PFAM: aldo/keto reductase; KEGG: mex:Mext_4689 aldo/keto reductase; aldo/keto reductase 5521348 7116192 Mchl_5154 Methylobacterium extorquens CM4 aldo/keto reductase YP_002423846.1 5520470 R 440085 CDS YP_002423847.1 218533031 7116193 complement(5521430..5522155) 1 NC_011757.1 KEGG: mex:Mext_4690 hypothetical protein; hypothetical protein 5522155 7116193 Mchl_5155 Methylobacterium extorquens CM4 hypothetical protein YP_002423847.1 5521430 R 440085 CDS YP_002423848.1 218533032 7116194 complement(5522351..5524348) 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_4691 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5524348 7116194 Mchl_5156 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423848.1 5522351 R 440085 CDS YP_002423849.1 218533033 7116195 complement(5524726..5526237) 1 NC_011757.1 KEGG: mex:Mext_4692 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 5526237 7116195 Mchl_5157 Methylobacterium extorquens CM4 protease Do YP_002423849.1 5524726 R 440085 CDS YP_002423850.1 218533034 7116196 complement(5526351..5527103) 1 NC_011757.1 KEGG: mex:Mext_4693 hypothetical protein; hypothetical protein 5527103 7116196 Mchl_5158 Methylobacterium extorquens CM4 hypothetical protein YP_002423850.1 5526351 R 440085 CDS YP_002423851.1 218533035 7116197 complement(5527100..5529820) 1 NC_011757.1 TIGRFAM: valyl-tRNA synthetase; KEGG: mex:Mext_4694 valyl-tRNA synthetase; valyl-tRNA synthetase 5529820 7116197 Mchl_5159 Methylobacterium extorquens CM4 valyl-tRNA synthetase YP_002423851.1 5527100 R 440085 CDS YP_002423852.1 218533036 7116198 complement(5530144..5530740) 1 NC_011757.1 KEGG: mex:Mext_4695 hypothetical protein; hypothetical protein 5530740 7116198 Mchl_5160 Methylobacterium extorquens CM4 hypothetical protein YP_002423852.1 5530144 R 440085 CDS YP_002423853.1 218533037 7116199 complement(5530866..5532332) 1 NC_011757.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: mex:Mext_4696 TolC family type I secretion outer membrane protein; TolC family type I secretion outer membrane protein 5532332 7116199 Mchl_5161 Methylobacterium extorquens CM4 TolC family type I secretion outer membrane protein YP_002423853.1 5530866 R 440085 CDS YP_002423854.1 218533038 7116200 complement(5532900..5533550) 1 NC_011757.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; KEGG: mex:Mext_4697 protein-L-isoaspartate(D-aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 5533550 7116200 Mchl_5162 Methylobacterium extorquens CM4 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_002423854.1 5532900 R 440085 CDS YP_002423855.1 218533039 7116204 5535292..5535594 1 NC_011757.1 KEGG: mex:Mext_4699 hypothetical protein; hypothetical protein 5535594 7116204 Mchl_5164 Methylobacterium extorquens CM4 hypothetical protein YP_002423855.1 5535292 D 440085 CDS YP_002423856.1 218533040 7116206 complement(5536563..5536793) 1 NC_011757.1 KEGG: mex:Mext_4701 hypothetical protein; hypothetical protein 5536793 7116206 Mchl_5166 Methylobacterium extorquens CM4 hypothetical protein YP_002423856.1 5536563 R 440085 CDS YP_002423857.1 218533041 7116207 complement(5537392..5537646) 1 NC_011757.1 KEGG: mex:Mext_3583 hypothetical protein; hypothetical protein 5537646 7116207 Mchl_5167 Methylobacterium extorquens CM4 hypothetical protein YP_002423857.1 5537392 R 440085 CDS YP_002423858.1 218533042 7116208 complement(5537795..5538019) 1 NC_011757.1 KEGG: mex:Mext_4702 hypothetical protein; hypothetical protein 5538019 7116208 Mchl_5168 Methylobacterium extorquens CM4 hypothetical protein YP_002423858.1 5537795 R 440085 CDS YP_002423859.1 218533043 7116209 complement(5538551..5538925) 1 NC_011757.1 KEGG: mex:Mext_4703 hypothetical protein; hypothetical protein 5538925 7116209 Mchl_5169 Methylobacterium extorquens CM4 hypothetical protein YP_002423859.1 5538551 R 440085 CDS YP_002423860.1 218533044 7116210 complement(5539101..5539376) 1 NC_011757.1 KEGG: mex:Mext_4704 hypothetical protein; hypothetical protein 5539376 7116210 Mchl_5170 Methylobacterium extorquens CM4 hypothetical protein YP_002423860.1 5539101 R 440085 CDS YP_002423861.1 218533045 7116211 complement(5539404..5539652) 1 NC_011757.1 KEGG: mex:Mext_4705 hypothetical protein; hypothetical protein 5539652 7116211 Mchl_5171 Methylobacterium extorquens CM4 hypothetical protein YP_002423861.1 5539404 R 440085 CDS YP_002423862.1 218533046 7116212 complement(5539852..5540019) 1 NC_011757.1 KEGG: mex:Mext_4706 hypothetical protein; hypothetical protein 5540019 7116212 Mchl_5172 Methylobacterium extorquens CM4 hypothetical protein YP_002423862.1 5539852 R 440085 CDS YP_002423863.1 218533047 7116213 complement(5540088..5540984) 1 NC_011757.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: hydroxyethylthiazole kinase; protein of unknown function UPF0031; KEGG: mex:Mext_4707 carbohydrate kinase, YjeF related protein; carbohydrate kinase 5540984 7116213 Mchl_5173 Methylobacterium extorquens CM4 carbohydrate kinase YP_002423863.1 5540088 R 440085 CDS YP_002423864.1 218533048 7116214 5541213..5541503 1 NC_011757.1 KEGG: mex:Mext_4708 hypothetical protein; hypothetical protein 5541503 7116214 Mchl_5174 Methylobacterium extorquens CM4 hypothetical protein YP_002423864.1 5541213 D 440085 CDS YP_002423865.1 218533049 7116215 5541577..5541939 1 NC_011757.1 KEGG: mex:Mext_4709 hypothetical protein; hypothetical protein 5541939 7116215 Mchl_5175 Methylobacterium extorquens CM4 hypothetical protein YP_002423865.1 5541577 D 440085 CDS YP_002423866.1 218533050 7116216 5542118..5542369 1 NC_011757.1 KEGG: mex:Mext_4710 hypothetical protein; hypothetical protein 5542369 7116216 Mchl_5176 Methylobacterium extorquens CM4 hypothetical protein YP_002423866.1 5542118 D 440085 CDS YP_002423867.1 218533051 7116217 5542500..5542667 1 NC_011757.1 KEGG: mpo:Mpop_5249 hypothetical protein; hypothetical protein 5542667 7116217 Mchl_5177 Methylobacterium extorquens CM4 hypothetical protein YP_002423867.1 5542500 D 440085 CDS YP_002423868.1 218533052 7116218 5543241..5543447 1 NC_011757.1 KEGG: mex:Mext_4711 hypothetical protein; hypothetical protein 5543447 7116218 Mchl_5178 Methylobacterium extorquens CM4 hypothetical protein YP_002423868.1 5543241 D 440085 CDS YP_002423869.1 218533053 7116219 complement(5543488..5543763) 1 NC_011757.1 KEGG: mex:Mext_4712 hypothetical protein; hypothetical protein 5543763 7116219 Mchl_5179 Methylobacterium extorquens CM4 hypothetical protein YP_002423869.1 5543488 R 440085 CDS YP_002423870.1 218533054 7116220 5544183..5545223 1 NC_011757.1 TIGRFAM: phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: mex:Mext_4713 phosphate ABC transporter periplasmic phosphate-binding protein; phosphate ABC transporter periplasmic phosphate-binding protein 5545223 7116220 Mchl_5180 Methylobacterium extorquens CM4 phosphate ABC transporter periplasmic phosphate-binding protein YP_002423870.1 5544183 D 440085 CDS YP_002423871.1 218533055 7116221 5545338..5546312 1 NC_011757.1 TIGRFAM: phosphate ABC transporter inner membrane subunit PstC; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mex:Mext_4714 phosphate ABC transporter inner membrane subunit PstC; phosphate ABC transporter inner membrane subunit PstC 5546312 7116221 Mchl_5181 Methylobacterium extorquens CM4 phosphate ABC transporter inner membrane subunit PstC YP_002423871.1 5545338 D 440085 CDS YP_002423872.1 218533056 7116222 5546357..5547250 1 NC_011757.1 TIGRFAM: phosphate ABC transporter inner membrane subunit PstA; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mpo:Mpop_5254 phosphate ABC transporter inner membrane subunit PstA; phosphate ABC transporter inner membrane subunit PstA 5547250 7116222 Mchl_5182 Methylobacterium extorquens CM4 phosphate ABC transporter inner membrane subunit PstA YP_002423872.1 5546357 D 440085 CDS YP_002423873.1 218533057 7116223 5547292..5548107 1 NC_011757.1 KEGG: mex:Mext_4716 phosphate ABC transporter ATPase subunit; TIGRFAM: phosphate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA; phosphate ABC transporter ATPase 5548107 7116223 Mchl_5183 Methylobacterium extorquens CM4 phosphate ABC transporter ATPase YP_002423873.1 5547292 D 440085 CDS YP_002423874.1 218533058 7116224 5548239..5548952 1 NC_011757.1 TIGRFAM: phosphate transporter regulatory protein PhoU; PFAM: PhoU family protein; KEGG: mex:Mext_4717 phosphate transporter regulatory protein PhoU; phosphate uptake regulator PhoU 5548952 7116224 Mchl_5184 Methylobacterium extorquens CM4 phosphate uptake regulator PhoU YP_002423874.1 5548239 D 440085 CDS YP_002423875.1 218533059 7116225 5549042..5549746 1 NC_011757.1 TIGRFAM: phosphate regulon transcriptional regulator PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_4718 phosphate regulon transcriptional regulator PhoB; winged helix family two component transcriptional regulator PhoB 5549746 7116225 Mchl_5185 Methylobacterium extorquens CM4 winged helix family two component transcriptional regulator PhoB YP_002423875.1 5549042 D 440085 CDS YP_002423876.1 218533060 7116226 complement(5549975..5550514) 1 NC_011757.1 PFAM: GcrA cell cycle regulator; KEGG: mex:Mext_4719 GcrA cell cycle regulator; GcrA cell cycle regulator 5550514 7116226 Mchl_5186 Methylobacterium extorquens CM4 GcrA cell cycle regulator YP_002423876.1 5549975 R 440085 CDS YP_002423877.1 218533061 7116227 5551026..5551892 1 NC_011757.1 PFAM: Domain of unknown function DUF1849; KEGG: mex:Mext_4720 hypothetical protein; hypothetical protein 5551892 7116227 Mchl_5187 Methylobacterium extorquens CM4 hypothetical protein YP_002423877.1 5551026 D 440085 CDS YP_002423878.1 218533062 7116228 complement(5551903..5553180) 1 NC_011757.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 5553180 7116228 Mchl_5188 Methylobacterium extorquens CM4 DNA polymerase IV YP_002423878.1 5551903 R 440085 CDS YP_002423879.1 218533063 7116229 5553237..5554058 1 NC_011757.1 KEGG: mex:Mext_4722 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 5554058 7116229 Mchl_5189 Methylobacterium extorquens CM4 precorrin-6x reductase YP_002423879.1 5553237 D 440085 CDS YP_002423880.1 218533064 7116230 5554084..5555586 1 NC_011757.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: mex:Mext_4723 cobyric acid synthase CobQ; cobyric acid synthase CobQ 5555586 7116230 Mchl_5190 Methylobacterium extorquens CM4 cobyric acid synthase CobQ YP_002423880.1 5554084 D 440085 CDS YP_002423881.1 218533065 7116231 complement(5555657..5556658) 1 NC_011757.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; KEGG: mex:Mext_4724 cobalamin biosynthesis protein CobD; cobalamin biosynthesis protein CobD 5556658 7116231 Mchl_5191 Methylobacterium extorquens CM4 cobalamin biosynthesis protein CobD YP_002423881.1 5555657 R 440085 CDS YP_002423882.1 218533066 7116232 5556664..5557680 1 NC_011757.1 TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: mex:Mext_4725 L-threonine-O-3-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase 5557680 7116232 Mchl_5192 Methylobacterium extorquens CM4 L-threonine-O-3-phosphate decarboxylase YP_002423882.1 5556664 D 440085 CDS YP_002423883.1 218533067 7116233 complement(5557673..5558857) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4726 major facilitator transporter; major facilitator superfamily protein 5558857 7116233 Mchl_5193 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423883.1 5557673 R 440085 CDS YP_002423884.1 218533068 7116234 5559264..5559467 1 NC_011757.1 KEGG: mex:Mext_4727 hypothetical protein; hypothetical protein 5559467 7116234 Mchl_5194 Methylobacterium extorquens CM4 hypothetical protein YP_002423884.1 5559264 D 440085 CDS YP_002423885.1 218533069 7116235 5559669..5561078 1 NC_011757.1 PFAM: malonyl-CoA decarboxylase; KEGG: mex:Mext_4728 malonyl-CoA decarboxylase; malonyl-CoA decarboxylase 5561078 7116235 Mchl_5195 Methylobacterium extorquens CM4 malonyl-CoA decarboxylase YP_002423885.1 5559669 D 440085 CDS YP_002423886.1 218533070 7116236 5561215..5561571 1 NC_011757.1 PFAM: CsbD family protein; KEGG: mex:Mext_4729 CsbD family protein; CsbD family protein 5561571 7116236 Mchl_5196 Methylobacterium extorquens CM4 CsbD family protein YP_002423886.1 5561215 D 440085 CDS YP_002423887.1 218533071 7116237 complement(5561725..5562510) 1 NC_011757.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_4730 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase 5562510 7116237 Mchl_5197 Methylobacterium extorquens CM4 3-hydroxybutyrate dehydrogenase YP_002423887.1 5561725 R 440085 CDS YP_002423888.1 218533072 7116238 5562715..5563677 1 NC_011757.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 5563677 7116238 Mchl_5198 Methylobacterium extorquens CM4 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002423888.1 5562715 D 440085 CDS YP_002423889.1 218533073 7116239 5563674..5564387 1 NC_011757.1 PFAM: protein of unkown function DUF1796 papain-like cysteine peptidase; KEGG: mex:Mext_4732 hypothetical protein; hypothetical protein 5564387 7116239 Mchl_5199 Methylobacterium extorquens CM4 hypothetical protein YP_002423889.1 5563674 D 440085 CDS YP_002423890.1 218533074 7116240 5564535..5565923 1 NC_011757.1 KEGG: mex:Mext_4733 hypothetical protein; hypothetical protein 5565923 7116240 Mchl_5200 Methylobacterium extorquens CM4 hypothetical protein YP_002423890.1 5564535 D 440085 CDS YP_002423891.1 218533075 7116241 5566122..5566526 1 NC_011757.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 5566526 rplS 7116241 rplS Methylobacterium extorquens CM4 50S ribosomal protein L19 YP_002423891.1 5566122 D 440085 CDS YP_002423892.1 218533076 7116242 5566582..5567040 1 NC_011757.1 PFAM: DNA polymerase beta domain protein region; KEGG: mpo:Mpop_5274 hypothetical protein; DNA polymerase beta domain-containing protein 5567040 7116242 Mchl_5202 Methylobacterium extorquens CM4 DNA polymerase beta domain-containing protein YP_002423892.1 5566582 D 440085 CDS YP_002423893.1 218533077 7116243 complement(5567316..5568512) 1 NC_011757.1 TIGRFAM: lytic murein transglycosylase; PFAM: peptidoglycan-binding protein; KEGG: mex:Mext_4736 lytic murein transglycosylase; lytic murein transglycosylase 5568512 7116243 Mchl_5203 Methylobacterium extorquens CM4 lytic murein transglycosylase YP_002423893.1 5567316 R 440085 CDS YP_002423894.1 218533078 7116244 5568965..5569582 1 NC_011757.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 5569582 rpsD 7116244 rpsD Methylobacterium extorquens CM4 30S ribosomal protein S4 YP_002423894.1 5568965 D 440085 CDS YP_002423895.1 218533079 7116245 complement(5569711..5570763) 1 NC_011757.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: mex:Mext_4738 2-nitropropane dioxygenase NPD; 2-nitropropane dioxygenase NPD 5570763 7116245 Mchl_5205 Methylobacterium extorquens CM4 2-nitropropane dioxygenase NPD YP_002423895.1 5569711 R 440085 CDS YP_002423896.1 218533080 7116246 complement(5570865..5571707) 1 NC_011757.1 KEGG: mex:Mext_4739 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-diacylglycerol/serine O-phosphatidyltransferase 5571707 7116246 Mchl_5206 Methylobacterium extorquens CM4 CDP-diacylglycerol/serine O-phosphatidyltransferase YP_002423896.1 5570865 R 440085 CDS YP_002423897.1 218533081 7116247 complement(5571782..5572492) 1 NC_011757.1 KEGG: mex:Mext_4740 phosphatidylserine decarboxylase related protein; TIGRFAM: phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related; phosphatidylserine decarboxylase-like protein 5572492 7116247 Mchl_5207 Methylobacterium extorquens CM4 phosphatidylserine decarboxylase-like protein YP_002423897.1 5571782 R 440085 CDS YP_002423898.1 218533082 7113654 complement(5572568..5574559) 1 NC_011757.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: ATPase AAA; KEGG: mex:Mext_4741 ABC transporter related; ABC transporter 5574559 7113654 Mchl_5208 Methylobacterium extorquens CM4 ABC transporter YP_002423898.1 5572568 R 440085 CDS YP_002423899.1 218533083 7113817 complement(5574618..5576153) 1 NC_011757.1 PFAM: peptidoglycan-binding LysM; KEGG: mex:Mext_4742 peptidoglycan-binding LysM; peptidoglycan-binding LysM 5576153 7113817 Mchl_5209 Methylobacterium extorquens CM4 peptidoglycan-binding LysM YP_002423899.1 5574618 R 440085 CDS YP_002423900.1 218533084 7113818 5576370..5576972 1 NC_011757.1 PFAM: conserved hypothetical protein; KEGG: mex:Mext_4743 hypothetical protein; hypothetical protein 5576972 7113818 Mchl_5210 Methylobacterium extorquens CM4 hypothetical protein YP_002423900.1 5576370 D 440085 CDS YP_002423901.1 218533085 7113819 5576972..5577763 1 NC_011757.1 KEGG: mex:Mext_4744 hypothetical protein; hypothetical protein 5577763 7113819 Mchl_5211 Methylobacterium extorquens CM4 hypothetical protein YP_002423901.1 5576972 D 440085 CDS YP_002423902.1 218533086 7113820 complement(5577819..5579207) 1 NC_011757.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 5579207 cysS 7113820 cysS Methylobacterium extorquens CM4 cysteinyl-tRNA synthetase YP_002423902.1 5577819 R 440085 CDS YP_002423903.1 218533087 7113821 5579536..5579859 1 NC_011757.1 KEGG: mex:Mext_4746 hypothetical protein; hypothetical protein 5579859 7113821 Mchl_5213 Methylobacterium extorquens CM4 hypothetical protein YP_002423903.1 5579536 D 440085 CDS YP_002423904.1 218533088 7113822 complement(5579873..5580427) 1 NC_011757.1 PFAM: CreA family protein; KEGG: mex:Mext_4747 CreA family protein; CreA family protein 5580427 7113822 Mchl_5214 Methylobacterium extorquens CM4 CreA family protein YP_002423904.1 5579873 R 440085 CDS YP_002423905.1 218533089 7113823 5580501..5581601 1 NC_011757.1 KEGG: mex:Mext_4748 hypothetical protein; hypothetical protein 5581601 7113823 Mchl_5215 Methylobacterium extorquens CM4 hypothetical protein YP_002423905.1 5580501 D 440085 CDS YP_002423906.1 218533090 7113824 5581765..5583936 1 NC_011757.1 PFAM: OmpA/MotB domain protein; KEGG: mex:Mext_4749 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 5583936 7113824 Mchl_5216 Methylobacterium extorquens CM4 OmpA/MotB domain-containing protein YP_002423906.1 5581765 D 440085 CDS YP_002423907.1 218533091 7113825 5584111..5585325 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4750 major facilitator transporter; major facilitator superfamily protein 5585325 7113825 Mchl_5217 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002423907.1 5584111 D 440085 CDS YP_002423908.1 218533092 7113826 5585414..5585905 1 NC_011757.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: mex:Mext_4751 3-demethylubiquinone-9 3-methyltransferase; 3-demethylubiquinone-9 3-methyltransferase 5585905 7113826 Mchl_5218 Methylobacterium extorquens CM4 3-demethylubiquinone-9 3-methyltransferase YP_002423908.1 5585414 D 440085 CDS YP_002423909.1 218533093 7113827 5585902..5586681 1 NC_011757.1 PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: mex:Mext_4752 methyltransferase type 11; type 11 methyltransferase 5586681 7113827 Mchl_5219 Methylobacterium extorquens CM4 type 11 methyltransferase YP_002423909.1 5585902 D 440085 CDS YP_002423910.1 218533094 7113828 complement(5586678..5588027) 1 NC_011757.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 5588027 7113828 Mchl_5220 Methylobacterium extorquens CM4 glutamyl-tRNA synthetase YP_002423910.1 5586678 R 440085 CDS YP_002423911.1 218533095 7113829 complement(5588084..5589163) 1 NC_011757.1 PFAM: secretion protein HlyD; KEGG: mex:Mext_4754 secretion protein HlyD; secretion protein HlyD 5589163 7113829 Mchl_5221 Methylobacterium extorquens CM4 secretion protein HlyD YP_002423911.1 5588084 R 440085 CDS YP_002423912.1 218533096 7113830 complement(5589160..5589354) 1 NC_011757.1 PFAM: protein of unknown function DUF1656; KEGG: mex:Mext_4755 hypothetical protein; hypothetical protein 5589354 7113830 Mchl_5222 Methylobacterium extorquens CM4 hypothetical protein YP_002423912.1 5589160 R 440085 CDS YP_002423913.1 218533097 7113831 complement(5589363..5591399) 1 NC_011757.1 PFAM: fusaric acid resistance protein conserved region; KEGG: mex:Mext_4756 fusaric acid resistance protein region; fusaric acid resistance protein conserved region 5591399 7113831 Mchl_5223 Methylobacterium extorquens CM4 fusaric acid resistance protein conserved region YP_002423913.1 5589363 R 440085 CDS YP_002423914.1 218533098 7113832 complement(5591396..5591830) 1 NC_011757.1 KEGG: mex:Mext_4757 hypothetical protein; hypothetical protein 5591830 7113832 Mchl_5224 Methylobacterium extorquens CM4 hypothetical protein YP_002423914.1 5591396 R 440085 CDS YP_002423915.1 218533099 7113833 complement(5591993..5592274) 1 NC_011757.1 KEGG: mex:Mext_4758 hypothetical protein; hypothetical protein 5592274 7113833 Mchl_5225 Methylobacterium extorquens CM4 hypothetical protein YP_002423915.1 5591993 R 440085 CDS YP_002423916.1 218533100 7113834 5592634..5593269 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_4759 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 5593269 7113834 Mchl_5226 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002423916.1 5592634 D 440085 CDS YP_002423917.1 218533101 7113835 complement(5594172..5595512) 1 NC_011757.1 TIGRFAM: Tol-Pal system beta propeller repeat protein TolB; PFAM: TolB domain protein; hypothetical protein; KEGG: mex:Mext_4760 beta-propeller repeat-containing to-pal system protein TolB; Tol-Pal system beta propeller repeat-containing protein TolB 5595512 7113835 Mchl_5227 Methylobacterium extorquens CM4 Tol-Pal system beta propeller repeat-containing protein TolB YP_002423917.1 5594172 R 440085 CDS YP_002423918.1 218533102 7113836 complement(5595591..5597006) 1 NC_011757.1 TIGRFAM: protein TolA; PFAM: Tol-Pal system TolA; KEGG: mex:Mext_4761 protein TolA; protein TolA 5597006 7113836 Mchl_5228 Methylobacterium extorquens CM4 protein TolA YP_002423918.1 5595591 R 440085 CDS YP_002423919.1 218533103 7113837 complement(5597021..5597470) 1 NC_011757.1 PFAM: biopolymertransporter ExbD/TolR; KEGG: mex:Mext_4762 biopolymer transporter ExbD/TolR; biopolymertransporter ExbD/TolR 5597470 7113837 Mchl_5229 Methylobacterium extorquens CM4 biopolymertransporter ExbD/TolR YP_002423919.1 5597021 R 440085 CDS YP_002423920.1 218533104 7113838 complement(5597520..5598236) 1 NC_011757.1 TIGRFAM: protein TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: mex:Mext_4763 protein TolQ; protein TolQ 5598236 7113838 Mchl_5230 Methylobacterium extorquens CM4 protein TolQ YP_002423920.1 5597520 R 440085 CDS YP_002423921.1 218533105 7113839 5598676..5599926 1 NC_011757.1 PFAM: chemotaxis sensory transducer; KEGG: mex:Mext_4764 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5599926 7113839 Mchl_5231 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002423921.1 5598676 D 440085 CDS YP_002423922.1 218533106 7113840 complement(5599913..5600344) 1 NC_011757.1 TIGRFAM: tol-pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: mex:Mext_4765 tol-pal system-associated acyl-CoA thioesterase; tol-pal system-associated acyl-CoA thioesterase 5600344 7113840 Mchl_5232 Methylobacterium extorquens CM4 tol-pal system-associated acyl-CoA thioesterase YP_002423922.1 5599913 R 440085 CDS YP_002423923.1 218533107 7113841 complement(5600515..5601231) 1 NC_011757.1 KEGG: mex:Mext_4766 hypothetical protein; hypothetical protein 5601231 7113841 Mchl_5233 Methylobacterium extorquens CM4 hypothetical protein YP_002423923.1 5600515 R 440085 CDS YP_002423924.1 218533108 7113842 complement(5601537..5602478) 1 NC_011757.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_4767 metallophosphoesterase; metallophosphoesterase 5602478 7113842 Mchl_5234 Methylobacterium extorquens CM4 metallophosphoesterase YP_002423924.1 5601537 R 440085 CDS YP_002423925.1 218533109 7113843 complement(5602471..5603541) 1 NC_011757.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 5603541 ruvB 7113843 ruvB Methylobacterium extorquens CM4 Holliday junction DNA helicase RuvB YP_002423925.1 5602471 R 440085 CDS YP_002423926.1 218533110 7113844 5603997..5605757 1 NC_011757.1 PFAM: peptidoglycan-binding protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: mex:Mext_4769 peptidoglycan binding domain-containing protein; ErfK/YbiS/YcfS/YnhG family protein 5605757 7113844 Mchl_5236 Methylobacterium extorquens CM4 ErfK/YbiS/YcfS/YnhG family protein YP_002423926.1 5603997 D 440085 CDS YP_002423927.1 218533111 7113845 5605904..5606431 1 NC_011757.1 PFAM: ferritin; KEGG: mex:Mext_4770 ferritin Dps family protein; ferritin 5606431 7113845 Mchl_5237 Methylobacterium extorquens CM4 ferritin YP_002423927.1 5605904 D 440085 CDS YP_002423928.1 218533112 7113846 complement(5606541..5609243) 1 NC_011757.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: mex:Mext_4771 GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 5609243 7113846 Mchl_5238 Methylobacterium extorquens CM4 GCN5-like N-acetyltransferase YP_002423928.1 5606541 R 440085 CDS YP_002423929.1 218533113 7113847 5609588..5610238 1 NC_011757.1 PFAM: class II aldolase/adducin family protein; KEGG: mex:Mext_4772 L-fuculose-phosphate aldolase; L-fuculose-phosphate aldolase 5610238 7113847 Mchl_5239 Methylobacterium extorquens CM4 L-fuculose-phosphate aldolase YP_002423929.1 5609588 D 440085 CDS YP_002423930.1 218533114 7113848 5610831..5611358 1 NC_011757.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mex:Mext_4773 ROSMUCR transcriptional regulator; MucR family transcriptional regulator 5611358 7113848 Mchl_5240 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002423930.1 5610831 D 440085 CDS YP_002423931.1 218533115 7113849 5611578..5612360 1 NC_011757.1 PFAM: restriction endonuclease; KEGG: mex:Mext_4774 restriction endonuclease; restriction endonuclease 5612360 7113849 Mchl_5241 Methylobacterium extorquens CM4 restriction endonuclease YP_002423931.1 5611578 D 440085 CDS YP_002423932.1 218533116 7113850 complement(5612363..5613664) 1 NC_011757.1 PFAM: PepSY-associated TM helix domain protein; KEGG: mex:Mext_4775 PepSY-associated TM helix domain-containing protein; PepSY-associated TM helix domain-containing protein 5613664 7113850 Mchl_5242 Methylobacterium extorquens CM4 PepSY-associated TM helix domain-containing protein YP_002423932.1 5612363 R 440085 CDS YP_002423933.1 218533117 7113851 5614143..5616326 1 NC_011757.1 KEGG: mex:Mext_4776 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; penicillin-binding protein, 1A family 5616326 7113851 Mchl_5243 Methylobacterium extorquens CM4 penicillin-binding protein, 1A family YP_002423933.1 5614143 D 440085 CDS YP_002423934.1 218533118 7113852 5616621..5617688 1 NC_011757.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mex:Mext_4777 adenylyl cyclase class-3/4/guanylyl cyclase; adenylate/guanylate cyclase 5617688 7113852 Mchl_5244 Methylobacterium extorquens CM4 adenylate/guanylate cyclase YP_002423934.1 5616621 D 440085 CDS YP_002423935.1 218533119 7113853 complement(5617707..5618105) 1 NC_011757.1 KEGG: mex:Mext_4778 hypothetical protein; hypothetical protein 5618105 7113853 Mchl_5245 Methylobacterium extorquens CM4 hypothetical protein YP_002423935.1 5617707 R 440085 CDS YP_002423936.1 218533120 7113854 5618408..5619307 1 NC_011757.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: mex:Mext_4779 cobyrinic acid ac-diamide synthase; cobyrinic acid ac-diamide synthase 5619307 7113854 Mchl_5246 Methylobacterium extorquens CM4 cobyrinic acid ac-diamide synthase YP_002423936.1 5618408 D 440085 CDS YP_002423937.1 218533121 7113855 5619297..5619821 1 NC_011757.1 KEGG: mex:Mext_4780 hypothetical protein; hypothetical protein 5619821 7113855 Mchl_5247 Methylobacterium extorquens CM4 hypothetical protein YP_002423937.1 5619297 D 440085 CDS YP_002423938.1 218533122 7113856 complement(5619846..5620190) 1 NC_011757.1 KEGG: mex:Mext_4781 hypothetical protein; hypothetical protein 5620190 7113856 Mchl_5248 Methylobacterium extorquens CM4 hypothetical protein YP_002423938.1 5619846 R 440085 CDS YP_002423939.1 218533123 7113857 complement(5620326..5621966) 1 NC_011757.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: mex:Mext_4782 chaperonin GroEL; chaperonin GroEL 5621966 7113857 Mchl_5249 Methylobacterium extorquens CM4 chaperonin GroEL YP_002423939.1 5620326 R 440085 CDS YP_002423940.1 218533124 7113858 complement(5622059..5622349) 1 NC_011757.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 5622349 groES 7113858 groES Methylobacterium extorquens CM4 co-chaperonin GroES YP_002423940.1 5622059 R 440085 CDS YP_002423941.1 218533125 7113859 5622564..5623568 1 NC_011757.1 PFAM: Mg+2 transporter protein CorA; KEGG: mex:Mext_4784 Mg+2 transporter protein CorA; Mg+2 transporter protein CorA 5623568 7113859 Mchl_5251 Methylobacterium extorquens CM4 Mg+2 transporter protein CorA YP_002423941.1 5622564 D 440085 CDS YP_002423942.1 218533126 7113860 complement(5623612..5624253) 1 NC_011757.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: mex:Mext_4785 multiple antibiotic resistance (MarC)-related protein; multiple antibiotic resistance (MarC)-like protein 5624253 7113860 Mchl_5252 Methylobacterium extorquens CM4 multiple antibiotic resistance (MarC)-like protein YP_002423942.1 5623612 R 440085 CDS YP_002423943.1 218533127 7113861 5624430..5625890 1 NC_011757.1 KEGG: mex:Mext_4786 O-antigen and teichoic acid-like export protein; O-antigen and teichoic acid-like export protein 5625890 7113861 Mchl_5253 Methylobacterium extorquens CM4 O-antigen and teichoic acid-like export protein YP_002423943.1 5624430 D 440085 CDS YP_002423944.1 218533128 7113862 5626023..5627213 1 NC_011757.1 PFAM: FAD linked oxidase; KEGG: mex:Mext_4787 FAD linked oxidase domain-containing protein; FAD linked oxidase 5627213 7113862 Mchl_5254 Methylobacterium extorquens CM4 FAD linked oxidase YP_002423944.1 5626023 D 440085 CDS YP_002423945.1 218533129 7113863 complement(5627227..5628867) 1 NC_011757.1 PFAM: phosphate transporter; KEGG: mex:Mext_4788 phosphate transporter; phosphate transporter 5628867 7113863 Mchl_5255 Methylobacterium extorquens CM4 phosphate transporter YP_002423945.1 5627227 R 440085 CDS YP_002423946.1 218533130 7113864 5629194..5629403 1 NC_011757.1 KEGG: mex:Mext_4789 hypothetical protein; hypothetical protein 5629403 7113864 Mchl_5256 Methylobacterium extorquens CM4 hypothetical protein YP_002423946.1 5629194 D 440085 CDS YP_002423947.1 218533131 7113865 5629503..5629688 1 NC_011757.1 KEGG: mex:Mext_4790 hypothetical protein; hypothetical protein 5629688 7113865 Mchl_5257 Methylobacterium extorquens CM4 hypothetical protein YP_002423947.1 5629503 D 440085 CDS YP_002423948.1 218533132 7113866 5629697..5629999 1 NC_011757.1 KEGG: mex:Mext_4791 hypothetical protein; hypothetical protein 5629999 7113866 Mchl_5258 Methylobacterium extorquens CM4 hypothetical protein YP_002423948.1 5629697 D 440085 CDS YP_002423949.1 218533133 7113867 5629996..5631513 1 NC_011757.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 5631513 glpD 7113867 glpD Methylobacterium extorquens CM4 glycerol-3-phosphate dehydrogenase YP_002423949.1 5629996 D 440085 CDS YP_002423950.1 218533134 7113868 complement(5631501..5632934) 1 NC_011757.1 KEGG: mex:Mext_4793 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 5632934 7113868 Mchl_5260 Methylobacterium extorquens CM4 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002423950.1 5631501 R 440085 CDS YP_002423951.1 218533135 7113869 complement(5633128..5635293) 1 NC_011757.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 5635293 7113869 Mchl_5261 Methylobacterium extorquens CM4 methylmalonyl-CoA mutase YP_002423951.1 5633128 R 440085 CDS YP_002423952.1 218533136 7113870 complement(5635399..5635899) 1 NC_011757.1 KEGG: mex:Mext_4795 hypothetical protein; hypothetical protein 5635899 7113870 Mchl_5262 Methylobacterium extorquens CM4 hypothetical protein YP_002423952.1 5635399 R 440085 CDS YP_002423953.1 218533137 7113871 5636015..5636944 1 NC_011757.1 PFAM: protein of unknown function DUF817; KEGG: mex:Mext_4796 hypothetical protein; hypothetical protein 5636944 7113871 Mchl_5263 Methylobacterium extorquens CM4 hypothetical protein YP_002423953.1 5636015 D 440085 CDS YP_002423954.1 218533138 7113872 complement(5636937..5637152) 1 NC_011757.1 KEGG: mex:Mext_4797 hypothetical protein; hypothetical protein 5637152 7113872 Mchl_5264 Methylobacterium extorquens CM4 hypothetical protein YP_002423954.1 5636937 R 440085 CDS YP_002423955.1 218533139 7113873 5637668..5638813 1 NC_011757.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: mex:Mext_4798 2-alkenal reductase; 2-alkenal reductase 5638813 7113873 Mchl_5265 Methylobacterium extorquens CM4 2-alkenal reductase YP_002423955.1 5637668 D 440085 CDS YP_002423956.1 218533140 7113874 5638883..5639578 1 NC_011757.1 PFAM: heat shock protein DnaJ domain protein; KEGG: mex:Mext_4799 heat shock protein DnaJ domain-containing protein; heat shock protein DnaJ domain-containing protein 5639578 7113874 Mchl_5266 Methylobacterium extorquens CM4 heat shock protein DnaJ domain-containing protein YP_002423956.1 5638883 D 440085 CDS YP_002423957.1 218533141 7113875 complement(5639808..5641292) 1 NC_011757.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; sporulation domain protein; KEGG: mex:Mext_4800 serine-type D-Ala-D-Ala carboxypeptidase; serine-type D-Ala-D-Ala carboxypeptidase 5641292 7113875 Mchl_5267 Methylobacterium extorquens CM4 serine-type D-Ala-D-Ala carboxypeptidase YP_002423957.1 5639808 R 440085 CDS YP_002423958.1 218533142 7113876 5641726..5642121 1 NC_011757.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: mpo:Mpop_5344 ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS 5642121 7113876 Mchl_5268 Methylobacterium extorquens CM4 ATP-dependent Clp protease adaptor protein ClpS YP_002423958.1 5641726 D 440085 CDS YP_002423959.1 218533143 7113877 5642144..5644627 1 NC_011757.1 KEGG: mex:Mext_4802 ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: ATPase AAA; Clp domain protein; ATPase AAA; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; ATP-dependent Clp protease ATP-binding subunit clpA 5644627 7113877 Mchl_5269 Methylobacterium extorquens CM4 ATP-dependent Clp protease ATP-binding subunit clpA YP_002423959.1 5642144 D 440085 CDS YP_002423960.1 218533144 7113878 5644763..5645035 1 NC_011757.1 KEGG: mex:Mext_4803 hypothetical protein; hypothetical protein 5645035 7113878 Mchl_5270 Methylobacterium extorquens CM4 hypothetical protein YP_002423960.1 5644763 D 440085 CDS YP_002423961.1 218533145 7113879 complement(5645048..5646265) 1 NC_011757.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 5646265 7113879 Mchl_5271 Methylobacterium extorquens CM4 5-aminolevulinate synthase YP_002423961.1 5645048 R 440085 CDS YP_002423962.1 218533146 7113880 complement(5646321..5647130) 1 NC_011757.1 TIGRFAM: photosynthetic complex assembly protein 2; KEGG: mex:Mext_4805 hypothetical protein; photosynthetic complex assembly protein 2 5647130 7113880 Mchl_5272 Methylobacterium extorquens CM4 photosynthetic complex assembly protein 2 YP_002423962.1 5646321 R 440085 CDS YP_002423963.1 218533147 7113881 complement(5647132..5648226) 1 NC_011757.1 oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis; magnesium-protoporphyrin IX monomethyl ester cyclase 5648226 7113881 Mchl_5273 Methylobacterium extorquens CM4 magnesium-protoporphyrin IX monomethyl ester cyclase YP_002423963.1 5647132 R 440085 CDS YP_002423964.1 218533148 7113882 complement(5648223..5648549) 1 NC_011757.1 KEGG: mex:Mext_4807 hypothetical protein; hypothetical protein 5648549 7113882 Mchl_5274 Methylobacterium extorquens CM4 hypothetical protein YP_002423964.1 5648223 R 440085 CDS YP_002423965.1 218533149 7113883 complement(5648549..5649019) 1 NC_011757.1 TIGRFAM: photosynthetic complex assembly protein; KEGG: mex:Mext_4808 hypothetical protein; photosynthetic complex assembly protein 5649019 7113883 Mchl_5275 Methylobacterium extorquens CM4 photosynthetic complex assembly protein YP_002423965.1 5648549 R 440085 CDS YP_002423966.1 218533150 7113884 complement(5649035..5649751) 1 NC_011757.1 KEGG: mex:Mext_4809 photosynthetic complex assembly protein; photosynthetic complex assembly protein 5649751 7113884 Mchl_5276 Methylobacterium extorquens CM4 photosynthetic complex assembly protein YP_002423966.1 5649035 R 440085 CDS YP_002423967.1 218533151 7113885 complement(5649763..5650536) 1 NC_011757.1 TIGRFAM: photosynthetic reaction center H subunit; PFAM: Photosynthetic reaction centre H subunit; KEGG: mex:Mext_4810 photosynthetic reaction center subunit H; photosynthetic reaction center H subunit 5650536 7113885 Mchl_5277 Methylobacterium extorquens CM4 photosynthetic reaction center H subunit YP_002423967.1 5649763 R 440085 CDS YP_002423968.1 218533152 7113886 complement(5650550..5651995) 1 NC_011757.1 PFAM: PUCC protein; major facilitator superfamily MFS_1; KEGG: mex:Mext_4811 PucC protein; PUCC protein 5651995 7113886 Mchl_5278 Methylobacterium extorquens CM4 PUCC protein YP_002423968.1 5650550 R 440085 CDS YP_002423969.1 218533153 7113887 complement(5651992..5652723) 1 NC_011757.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine; Mg-protoporphyrin IX methyl transferase 5652723 7113887 Mchl_5279 Methylobacterium extorquens CM4 Mg-protoporphyrin IX methyl transferase YP_002423969.1 5651992 R 440085 CDS YP_002423970.1 218533154 7113888 complement(5652723..5653616) 1 NC_011757.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production; protochlorophyllide reductase iron-sulfur ATP-binding protein 5653616 chlL 7113888 chlL Methylobacterium extorquens CM4 protochlorophyllide reductase iron-sulfur ATP-binding protein YP_002423970.1 5652723 R 440085 CDS YP_002423971.1 218533155 7113889 complement(5653613..5657329) 1 NC_011757.1 involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; the enzyme from Rhodobacter capsulatus contains an Fe-S cluster; part of a complex with BchI, BchD, and BchH; magnesium chelatase subunit H 5657329 bchH 7113889 bchH Methylobacterium extorquens CM4 magnesium chelatase subunit H YP_002423971.1 5653613 R 440085 CDS YP_002423972.1 218533156 7113890 complement(5657304..5658899) 1 NC_011757.1 light-independent reduction of protochlorophyllide to form chlorophyllide a; light-independent protochlorophyllide reductase subunit B 5658899 7113890 Mchl_5282 Methylobacterium extorquens CM4 light-independent protochlorophyllide reductase subunit B YP_002423972.1 5657304 R 440085 CDS YP_002423973.1 218533157 7113891 complement(5658905..5660173) 1 NC_011757.1 light-independent reduction of protochlorophyllide to form chlorophyllide a; light-independent protochlorophyllide reductase subunit N 5660173 7113891 Mchl_5283 Methylobacterium extorquens CM4 light-independent protochlorophyllide reductase subunit N YP_002423973.1 5658905 R 440085 CDS YP_002423974.1 218533158 7113892 complement(5660170..5660673) 1 NC_011757.1 PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: mex:Mext_4817 2-vinyl bacteriochlorophyllide hydratase; 2-vinyl bacteriochlorophyllide hydratase 5660673 7113892 Mchl_5284 Methylobacterium extorquens CM4 2-vinyl bacteriochlorophyllide hydratase YP_002423974.1 5660170 R 440085 CDS YP_002423975.1 218533159 7113893 5660930..5661817 1 NC_011757.1 KEGG: mex:Mext_4818 cobalamin B12-binding; cobalamin B12-binding 5661817 7113893 Mchl_5285 Methylobacterium extorquens CM4 cobalamin B12-binding YP_002423975.1 5660930 D 440085 CDS YP_002423976.1 218533160 7113894 5661863..5663305 1 NC_011757.1 KEGG: mex:Mext_4819 transcriptional regulator PpsR; TIGRFAM: transcriptional regulator PpsR; PFAM: helix-turn-helix Fis-type; PAS fold domain protein; SMART: PAS domain containing protein; Fis family transcriptional regulator 5663305 7113894 Mchl_5286 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002423976.1 5661863 D 440085 CDS YP_002423977.1 218533161 7113895 5663428..5664315 1 NC_011757.1 TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: mex:Mext_4820 bacteriochlorophyll/chlorophyll a synthase; bacteriochlorophyll/chlorophyll a synthase 5664315 7113895 Mchl_5287 Methylobacterium extorquens CM4 bacteriochlorophyll/chlorophyll a synthase YP_002423977.1 5663428 D 440085 CDS YP_002423978.1 218533162 7113896 5664312..5665688 1 NC_011757.1 PFAM: PUCC protein; major facilitator superfamily MFS_1; KEGG: mex:Mext_4821 PucC protein; PUCC protein 5665688 7113896 Mchl_5288 Methylobacterium extorquens CM4 PUCC protein YP_002423978.1 5664312 D 440085 CDS YP_002423979.1 218533163 7118146 5665693..5666886 1 NC_011757.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_4822 geranylgeranyl reductase; geranylgeranyl reductase 5666886 7118146 Mchl_5289 Methylobacterium extorquens CM4 geranylgeranyl reductase YP_002423979.1 5665693 D 440085 CDS YP_002423980.1 218533164 7118391 5666883..5667380 1 NC_011757.1 PFAM: TspO/MBR family protein; KEGG: mex:Mext_4823 TspO/MBR family protein; TspO and MBR-like protein 5667380 7118391 Mchl_5290 Methylobacterium extorquens CM4 TspO and MBR-like protein YP_002423980.1 5666883 D 440085 CDS YP_002423981.1 218533165 7118392 5667384..5667749 1 NC_011757.1 KEGG: mex:Mext_4824 hypothetical protein; hypothetical protein 5667749 7118392 Mchl_5291 Methylobacterium extorquens CM4 hypothetical protein YP_002423981.1 5667384 D 440085 CDS YP_002423982.1 218533166 7118393 5667793..5669388 1 NC_011757.1 PFAM: cytochrome C class I; KEGG: mex:Mext_4825 gluconate 2-dehydrogenase (acceptor); gluconate 2-dehydrogenase (acceptor) 5669388 7118393 Mchl_5292 Methylobacterium extorquens CM4 gluconate 2-dehydrogenase (acceptor) YP_002423982.1 5667793 D 440085 CDS YP_002423983.1 218533167 7118394 5669563..5670555 1 NC_011757.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 5670555 7118394 Mchl_5293 Methylobacterium extorquens CM4 6-phosphogluconate dehydrogenase YP_002423983.1 5669563 D 440085 CDS YP_002423984.1 218533168 7118395 5670552..5671283 1 NC_011757.1 TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: mex:Mext_4827 6-phosphogluconolactonase; 6-phosphogluconolactonase 5671283 7118395 Mchl_5294 Methylobacterium extorquens CM4 6-phosphogluconolactonase YP_002423984.1 5670552 D 440085 CDS YP_002423985.1 218533169 7118396 5671396..5671962 1 NC_011757.1 KEGG: mex:Mext_4828 hypothetical protein; hypothetical protein 5671962 7118396 Mchl_5295 Methylobacterium extorquens CM4 hypothetical protein YP_002423985.1 5671396 D 440085 CDS YP_002423986.1 218533170 7118397 complement(5672075..5673847) 1 NC_011757.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABC transporter 5673847 7118397 Mchl_5296 Methylobacterium extorquens CM4 cyclic beta-1,2-glucan ABC transporter YP_002423986.1 5672075 R 440085 CDS YP_002423987.1 218533171 7118398 5674118..5674891 1 NC_011757.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: mex:Mext_4830 MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel 5674891 7118398 Mchl_5297 Methylobacterium extorquens CM4 MotA/TolQ/ExbB proton channel YP_002423987.1 5674118 D 440085 CDS YP_002423988.1 218533172 7118399 5674906..5675739 1 NC_011757.1 PFAM: OmpA/MotB domain protein; KEGG: mex:Mext_4831 OmpA/MotB domain-containing protein; OmpA/MotB domain-containing protein 5675739 7118399 Mchl_5298 Methylobacterium extorquens CM4 OmpA/MotB domain-containing protein YP_002423988.1 5674906 D 440085 CDS YP_002423989.1 218533173 7118400 complement(5675761..5676267) 1 NC_011757.1 PFAM: SCP-like extracellular; KEGG: mpo:Mpop_5377 SCP-like extracellular; SCP-like extracellular 5676267 7118400 Mchl_5299 Methylobacterium extorquens CM4 SCP-like extracellular YP_002423989.1 5675761 R 440085 CDS YP_002423990.1 218533174 7118401 complement(5676393..5679122) 1 NC_011757.1 PFAM: MscS Mechanosensitive ion channel; KEGG: mex:Mext_4833 MscS mechanosensitive ion channel; mechanosensitive ion channel MscS 5679122 7118401 Mchl_5300 Methylobacterium extorquens CM4 mechanosensitive ion channel MscS YP_002423990.1 5676393 R 440085 CDS YP_002423991.1 218533175 7118402 5679834..5680382 1 NC_011757.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: mex:Mext_4834 HNH endonuclease; HNH endonuclease 5680382 7118402 Mchl_5301 Methylobacterium extorquens CM4 HNH endonuclease YP_002423991.1 5679834 D 440085 CDS YP_002423992.1 218533176 7118403 complement(5680390..5680641) 1 NC_011757.1 KEGG: mpo:Mpop_5380 hypothetical protein; hypothetical protein 5680641 7118403 Mchl_5302 Methylobacterium extorquens CM4 hypothetical protein YP_002423992.1 5680390 R 440085 CDS YP_002423993.1 218533177 7118404 complement(5680668..5681567) 1 NC_011757.1 PFAM: porin; KEGG: mpo:Mpop_5381 outer membrane insertion C-terminal signal; porin 5681567 7118404 Mchl_5303 Methylobacterium extorquens CM4 porin YP_002423993.1 5680668 R 440085 CDS YP_002423994.1 218533178 7118405 complement(5681806..5682663) 1 NC_011757.1 PFAM: porin opacity type; porin; KEGG: mex:Mext_4836 porin opacity type; porin opacity type 5682663 7118405 Mchl_5304 Methylobacterium extorquens CM4 porin opacity type YP_002423994.1 5681806 R 440085 CDS YP_002423995.1 218533179 7118406 complement(5682844..5683707) 1 NC_011757.1 KEGG: mex:Mext_4837 hypothetical protein; hypothetical protein 5683707 7118406 Mchl_5305 Methylobacterium extorquens CM4 hypothetical protein YP_002423995.1 5682844 R 440085 CDS YP_002423996.1 218533180 7118407 complement(5683971..5685311) 1 NC_011757.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 5685311 glmM 7118407 glmM Methylobacterium extorquens CM4 phosphoglucosamine mutase YP_002423996.1 5683971 R 440085 CDS YP_002423997.1 218533181 7118408 complement(5685498..5686247) 1 NC_011757.1 PFAM: protein of unknown function DUF81; KEGG: mex:Mext_4839 hypothetical protein; hypothetical protein 5686247 7118408 Mchl_5307 Methylobacterium extorquens CM4 hypothetical protein YP_002423997.1 5685498 R 440085 CDS YP_002423998.1 218533182 7118409 complement(5686363..5688291) 1 NC_011757.1 KEGG: mex:Mext_4840 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent metalloprotease FtsH 5688291 7118409 Mchl_5308 Methylobacterium extorquens CM4 ATP-dependent metalloprotease FtsH YP_002423998.1 5686363 R 440085 CDS YP_002423999.1 218533183 7118410 complement(5688429..5689472) 1 NC_011757.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: mex:Mext_4841 tRNA(Ile)-lysidine synthetase; tRNA(Ile)-lysidine synthetase 5689472 7118410 Mchl_5309 Methylobacterium extorquens CM4 tRNA(Ile)-lysidine synthetase YP_002423999.1 5688429 R 440085 CDS YP_002424000.1 218533184 7118411 complement(5689469..5690494) 1 NC_011757.1 TIGRFAM: tol-pal system protein YbgF; KEGG: mex:Mext_4842 tol-pal system protein YbgF; tol-pal system protein YbgF 5690494 7118411 Mchl_5310 Methylobacterium extorquens CM4 tol-pal system protein YbgF YP_002424000.1 5689469 R 440085 CDS YP_002424001.1 218533185 7118412 complement(5690668..5691180) 1 NC_011757.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: mex:Mext_4843 peptidoglycan-associated lipoprotein; peptidoglycan-associated lipoprotein 5691180 7118412 Mchl_5311 Methylobacterium extorquens CM4 peptidoglycan-associated lipoprotein YP_002424001.1 5690668 R 440085 CDS YP_002424002.1 218533186 7118413 complement(5691564..5691917) 1 NC_011757.1 KEGG: mex:Mext_4844 hypothetical protein; hypothetical protein 5691917 7118413 Mchl_5312 Methylobacterium extorquens CM4 hypothetical protein YP_002424002.1 5691564 R 440085 CDS YP_002424003.1 218533187 7118414 5692020..5692418 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4845 response regulator receiver; response regulator receiver protein 5692418 7118414 Mchl_5313 Methylobacterium extorquens CM4 response regulator receiver protein YP_002424003.1 5692020 D 440085 CDS YP_002424004.1 218533188 7118415 complement(5692514..5693410) 1 NC_011757.1 KEGG: mex:Mext_4846 hypothetical protein; hypothetical protein 5693410 7118415 Mchl_5314 Methylobacterium extorquens CM4 hypothetical protein YP_002424004.1 5692514 R 440085 CDS YP_002424005.1 218533189 7118416 5693584..5694645 1 NC_011757.1 PFAM: GSCFA domain protein; KEGG: mex:Mext_4847 GSCFA domain-containing protein; GSCFA domain-containing protein 5694645 7118416 Mchl_5315 Methylobacterium extorquens CM4 GSCFA domain-containing protein YP_002424005.1 5693584 D 440085 CDS YP_002424006.1 218533190 7118417 complement(5694793..5695722) 1 NC_011757.1 KEGG: mex:Mext_4848 porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: porphobilinogen deaminase; porphobilinogen deaminase 5695722 7118417 Mchl_5316 Methylobacterium extorquens CM4 porphobilinogen deaminase YP_002424006.1 5694793 R 440085 CDS YP_002424007.1 218533191 7118419 complement(5696052..5697116) 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_4388 integrase family protein; integrase family protein 5697116 7118419 Mchl_5317 Methylobacterium extorquens CM4 integrase family protein YP_002424007.1 5696052 R 440085 CDS YP_002424008.1 218533192 7118421 complement(5700531..5702783) 1 NC_011757.1 KEGG: met:M446_5543 RecD/TraA family helicase; TIGRFAM: helicase, RecD/TraA family; SMART: DNA-binding protein; ATPase AAA; RecD/TraA family helicase 5702783 7118421 Mchl_5319 Methylobacterium extorquens CM4 RecD/TraA family helicase YP_002424008.1 5700531 R 440085 CDS YP_002424009.1 218533193 7118422 complement(5703035..5703244) 1 NC_011757.1 hypothetical protein 5703244 7118422 Mchl_5320 Methylobacterium extorquens CM4 hypothetical protein YP_002424009.1 5703035 R 440085 CDS YP_002424010.1 218533194 7118423 complement(5703232..5703528) 1 NC_011757.1 hypothetical protein 5703528 7118423 Mchl_5321 Methylobacterium extorquens CM4 hypothetical protein YP_002424010.1 5703232 R 440085 CDS YP_002424011.1 218533195 7118424 5703745..5703906 1 NC_011757.1 hypothetical protein 5703906 7118424 Mchl_5322 Methylobacterium extorquens CM4 hypothetical protein YP_002424011.1 5703745 D 440085 CDS YP_002424012.1 218533196 7118425 complement(5703944..5704627) 1 NC_011757.1 hypothetical protein 5704627 7118425 Mchl_5323 Methylobacterium extorquens CM4 hypothetical protein YP_002424012.1 5703944 R 440085 CDS YP_002424013.1 218533197 7118426 complement(5704786..5704977) 1 NC_011757.1 hypothetical protein 5704977 7118426 Mchl_5324 Methylobacterium extorquens CM4 hypothetical protein YP_002424013.1 5704786 R 440085 CDS YP_002424014.1 218533198 7118427 5705085..5705219 1 NC_011757.1 hypothetical protein 5705219 7118427 Mchl_5325 Methylobacterium extorquens CM4 hypothetical protein YP_002424014.1 5705085 D 440085 CDS YP_002424015.1 218533199 7118428 complement(5705163..5705291) 1 NC_011757.1 hypothetical protein 5705291 7118428 Mchl_5326 Methylobacterium extorquens CM4 hypothetical protein YP_002424015.1 5705163 R 440085 CDS YP_002424016.1 218533200 7118429 complement(5705288..5705770) 1 NC_011757.1 KEGG: mrd:Mrad2831_2006 heat shock protein DnaJ domain-containing protein; heat shock protein DnaJ domain-containing protein 5705770 7118429 Mchl_5327 Methylobacterium extorquens CM4 heat shock protein DnaJ domain-containing protein YP_002424016.1 5705288 R 440085 CDS YP_002424017.1 218533201 7118430 complement(5705767..5705994) 1 NC_011757.1 KEGG: bvi:Bcep1808_6235 hypothetical protein; hypothetical protein 5705994 7118430 Mchl_5328 Methylobacterium extorquens CM4 hypothetical protein YP_002424017.1 5705767 R 440085 CDS YP_002424018.1 218533202 7119005 complement(5705994..5707184) 1 NC_011757.1 KEGG: rsq:Rsph17025_4201 hypothetical protein; hypothetical protein 5707184 7119005 Mchl_5329 Methylobacterium extorquens CM4 hypothetical protein YP_002424018.1 5705994 R 440085 CDS YP_002424019.1 218533203 7114365 5708243..5708908 1 NC_011757.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: rpb:RPB_3655 SAM binding protein; type 12 methyltransferase 5708908 7114365 Mchl_5330 Methylobacterium extorquens CM4 type 12 methyltransferase YP_002424019.1 5708243 D 440085 CDS YP_002424020.1 218533204 7116248 complement(5709063..5709461) 1 NC_011757.1 KEGG: mrd:Mrad2831_5275 hypothetical protein; hypothetical protein 5709461 7116248 Mchl_5331 Methylobacterium extorquens CM4 hypothetical protein YP_002424020.1 5709063 R 440085 CDS YP_002424021.1 218533205 7116249 5710008..5711189 1 NC_011757.1 KEGG: ava:Ava_1781 hypothetical protein; hypothetical protein 5711189 7116249 Mchl_5332 Methylobacterium extorquens CM4 hypothetical protein YP_002424021.1 5710008 D 440085 CDS YP_002424022.1 218533206 7116251 5713665..5714729 1 NC_011757.1 PFAM: integrase family protein; KEGG: mex:Mext_4388 integrase family protein; integrase family protein 5714729 7116251 Mchl_5334 Methylobacterium extorquens CM4 integrase family protein YP_002424022.1 5713665 D 440085 CDS YP_002424023.1 218533207 7116252 5715442..5716545 1 NC_011757.1 KEGG: nha:Nham_3713 hypothetical protein; hypothetical protein 5716545 7116252 Mchl_5335 Methylobacterium extorquens CM4 hypothetical protein YP_002424023.1 5715442 D 440085 CDS YP_002424024.1 218533208 7116253 complement(5717226..5718842) 1 NC_011757.1 KEGG: mex:Mext_4849 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; gamma-glutamyltransferase 5718842 7116253 Mchl_5336 Methylobacterium extorquens CM4 gamma-glutamyltransferase YP_002424024.1 5717226 R 440085 CDS YP_002424025.1 218533209 7116254 complement(5719016..5719909) 1 NC_011757.1 PFAM: polysaccharide deacetylase; KEGG: mex:Mext_4850 polysaccharide deacetylase; polysaccharide deacetylase 5719909 7116254 Mchl_5337 Methylobacterium extorquens CM4 polysaccharide deacetylase YP_002424025.1 5719016 R 440085 CDS YP_002424026.1 218533210 7116255 complement(5719951..5722422) 1 NC_011757.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: ATPase AAA; KEGG: mex:Mext_4851 ABC transporter; ABC transporter 5722422 7116255 Mchl_5338 Methylobacterium extorquens CM4 ABC transporter YP_002424026.1 5719951 R 440085 CDS YP_002424027.1 218533211 7116256 complement(5722425..5723294) 1 NC_011757.1 PFAM: inner-membrane translocator; KEGG: mex:Mext_4852 inner-membrane translocator; inner-membrane translocator 5723294 7116256 Mchl_5339 Methylobacterium extorquens CM4 inner-membrane translocator YP_002424027.1 5722425 R 440085 CDS YP_002424028.1 218533212 7116257 complement(5723344..5724534) 1 NC_011757.1 PFAM: extracellular ligand-binding receptor; KEGG: mex:Mext_4853 extracellular ligand-binding receptor; extracellular ligand-binding receptor 5724534 7116257 Mchl_5340 Methylobacterium extorquens CM4 extracellular ligand-binding receptor YP_002424028.1 5723344 R 440085 CDS YP_002424029.1 218533213 7116258 5724745..5725155 1 NC_011757.1 KEGG: mex:Mext_4854 hypothetical protein; hypothetical protein 5725155 7116258 Mchl_5341 Methylobacterium extorquens CM4 hypothetical protein YP_002424029.1 5724745 D 440085 CDS YP_002424030.1 218533214 7116259 complement(5725160..5725861) 1 NC_011757.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: mex:Mext_4855 GntR domain-containing protein; GntR family transcriptional regulator 5725861 7116259 Mchl_5342 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002424030.1 5725160 R 440085 CDS YP_002424031.1 218533215 7116260 complement(5726294..5726749) 1 NC_011757.1 KEGG: mex:Mext_4857 hypothetical protein; hypothetical protein 5726749 7116260 Mchl_5343 Methylobacterium extorquens CM4 hypothetical protein YP_002424031.1 5726294 R 440085 CDS YP_002424032.1 218533216 7116261 complement(5727705..5727974) 1 NC_011757.1 hypothetical protein 5727974 7116261 Mchl_5344 Methylobacterium extorquens CM4 hypothetical protein YP_002424032.1 5727705 R 440085 CDS YP_002424033.1 218533217 7116262 complement(5728154..5729170) 1 NC_011757.1 PFAM: helix-turn-helix domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; KEGG: mex:Mext_4859 PAS domain-containing protein; PAS fold-3 domain-containing protein 5729170 7116262 Mchl_5345 Methylobacterium extorquens CM4 PAS fold-3 domain-containing protein YP_002424033.1 5728154 R 440085 CDS YP_002424034.1 218533218 7116263 complement(5729567..5730901) 1 NC_011757.1 PFAM: major facilitator superfamily MFS_1; KEGG: mex:Mext_4861 major facilitator transporter; major facilitator superfamily protein 5730901 7116263 Mchl_5346 Methylobacterium extorquens CM4 major facilitator superfamily protein YP_002424034.1 5729567 R 440085 CDS YP_002424035.1 218533219 7116264 5731183..5731686 1 NC_011757.1 PFAM: protein of unknown function DUF892; KEGG: mex:Mext_4862 hypothetical protein; hypothetical protein 5731686 7116264 Mchl_5347 Methylobacterium extorquens CM4 hypothetical protein YP_002424035.1 5731183 D 440085 CDS YP_002424036.1 218533220 7116265 5731858..5733351 1 NC_011757.1 PFAM: protein of unknown function UPF0061; KEGG: mex:Mext_4863 hypothetical protein; hypothetical protein 5733351 7116265 Mchl_5348 Methylobacterium extorquens CM4 hypothetical protein YP_002424036.1 5731858 D 440085 CDS YP_002424037.1 218533221 7116266 5734017..5735792 1 NC_011757.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mex:Mext_4864 acetolactate synthase large subunit; acetolactate synthase, large subunit, biosynthetic type 5735792 7116266 Mchl_5349 Methylobacterium extorquens CM4 acetolactate synthase, large subunit, biosynthetic type YP_002424037.1 5734017 D 440085 CDS YP_002424038.1 218533222 7116267 complement(5735853..5736764) 1 NC_011757.1 KEGG: mex:Mext_4865 hypothetical protein; hypothetical protein 5736764 7116267 Mchl_5350 Methylobacterium extorquens CM4 hypothetical protein YP_002424038.1 5735853 R 440085 CDS YP_002424039.1 218533223 7116268 5736871..5737413 1 NC_011757.1 TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; acetolactate synthase small subunit; KEGG: mex:Mext_4866 acetolactate synthase, small subunit; acetolactate synthase, small subunit 5737413 7116268 Mchl_5351 Methylobacterium extorquens CM4 acetolactate synthase, small subunit YP_002424039.1 5736871 D 440085 CDS YP_002424040.1 218533224 7116269 5737476..5738120 1 NC_011757.1 PFAM: glutathione S-transferase domain; KEGG: mex:Mext_4867 glutathione S-transferase domain-containing protein; glutathione S-transferase domain-containing protein 5738120 7116269 Mchl_5352 Methylobacterium extorquens CM4 glutathione S-transferase domain-containing protein YP_002424040.1 5737476 D 440085 CDS YP_002424041.1 218533225 7116270 5738344..5740113 1 NC_011757.1 KEGG: mex:Mext_4868 asparagine synthase amidotransferase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase family amidotransferase; PFAM: glutamine amidotransferase class-II; asparagine synthase; asparagine synthase family amidotransferase 5740113 7116270 Mchl_5353 Methylobacterium extorquens CM4 asparagine synthase family amidotransferase YP_002424041.1 5738344 D 440085 CDS YP_002424042.1 218533226 7116271 5740269..5741108 1 NC_011757.1 PFAM: glutamine amidotransferase class-II; KEGG: mex:Mext_4869 glutamine amidotransferase class-II; class II glutamine amidotransferase 5741108 7116271 Mchl_5354 Methylobacterium extorquens CM4 class II glutamine amidotransferase YP_002424042.1 5740269 D 440085 CDS YP_002424043.1 218533227 7116272 complement(5741256..5742002) 1 NC_011757.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_4870 sigma-70 family RNA polymerase sigma factor; ECF subfamily RNA polymerase sigma-24 subunit 5742002 7116272 Mchl_5355 Methylobacterium extorquens CM4 ECF subfamily RNA polymerase sigma-24 subunit YP_002424043.1 5741256 R 440085 CDS YP_002424044.1 218533228 7116273 5742290..5744251 1 NC_011757.1 KEGG: mex:Mext_4871 hypothetical protein; hypothetical protein 5744251 7116273 Mchl_5356 Methylobacterium extorquens CM4 hypothetical protein YP_002424044.1 5742290 D 440085 CDS YP_002424045.1 218533229 7116274 5744406..5744672 1 NC_011757.1 KEGG: mex:Mext_4872 hypothetical protein; hypothetical protein 5744672 7116274 Mchl_5357 Methylobacterium extorquens CM4 hypothetical protein YP_002424045.1 5744406 D 440085 CDS YP_002424046.1 218533230 7116275 complement(5744893..5745939) 1 NC_011757.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: mex:Mext_4873 histidine kinase dimerisation/phosphoacceptor; signal transduction histidine kinase 5745939 7116275 Mchl_5358 Methylobacterium extorquens CM4 signal transduction histidine kinase YP_002424046.1 5744893 R 440085 CDS YP_002424047.1 218533231 7116276 complement(5745936..5746382) 1 NC_011757.1 PFAM: response regulator receiver; KEGG: mex:Mext_4874 response regulator receiver; response regulator receiver protein 5746382 7116276 Mchl_5359 Methylobacterium extorquens CM4 response regulator receiver protein YP_002424047.1 5745936 R 440085 CDS YP_002424048.1 218533232 7116277 complement(5746385..5748283) 1 NC_011757.1 KEGG: mex:Mext_4875 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; MHYT domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein; PAS/PAC sensor signal transduction histidine kinase 5748283 7116277 Mchl_5360 Methylobacterium extorquens CM4 PAS/PAC sensor signal transduction histidine kinase YP_002424048.1 5746385 R 440085 CDS YP_002424049.1 218533233 7116278 5748610..5749509 1 NC_011757.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: mex:Mext_4876 cyclic nucleotide-binding; Crp/Fnr family transcriptional regulator 5749509 7116278 Mchl_5361 Methylobacterium extorquens CM4 Crp/Fnr family transcriptional regulator YP_002424049.1 5748610 D 440085 CDS YP_002424050.1 218533234 7116279 complement(5749559..5751490) 1 NC_011757.1 KEGG: mex:Mext_4877 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; response regulator receiver; GAF domain protein; Sigma-70 region 4 type 2; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; LuxR family transcriptional regulator 5751490 7116279 Mchl_5362 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002424050.1 5749559 R 440085 CDS YP_002424051.1 218533235 7116280 5752410..5752847 1 NC_011757.1 hypothetical protein 5752847 7116280 Mchl_5363 Methylobacterium extorquens CM4 hypothetical protein YP_002424051.1 5752410 D 440085 CDS YP_002424052.1 218533236 7116283 5755109..5755282 1 NC_011757.1 KEGG: met:M446_0726 hypothetical protein; hypothetical protein 5755282 7116283 Mchl_5366 Methylobacterium extorquens CM4 hypothetical protein YP_002424052.1 5755109 D 440085 CDS YP_002424053.1 218533237 7116284 complement(5756975..5757145) 1 NC_011757.1 hypothetical protein 5757145 7116284 Mchl_5367 Methylobacterium extorquens CM4 hypothetical protein YP_002424053.1 5756975 R 440085 CDS YP_002424054.1 218533238 7116285 complement(5757698..5759005) 1 NC_011757.1 KEGG: mpo:Mpop_5454 hypothetical protein; hypothetical protein 5759005 7116285 Mchl_5368 Methylobacterium extorquens CM4 hypothetical protein YP_002424054.1 5757698 R 440085 CDS YP_002424055.1 218533239 7116286 complement(5759059..5759661) 1 NC_011757.1 KEGG: vei:Veis_3747 hypothetical protein; hypothetical protein 5759661 7116286 Mchl_5369 Methylobacterium extorquens CM4 hypothetical protein YP_002424055.1 5759059 R 440085 CDS YP_002424056.1 218533240 7116287 complement(5759658..5760254) 1 NC_011757.1 hypothetical protein 5760254 7116287 Mchl_5370 Methylobacterium extorquens CM4 hypothetical protein YP_002424056.1 5759658 R 440085 CDS YP_002424057.1 218533241 7116288 complement(5760487..5761131) 1 NC_011757.1 KEGG: ypg:YpAngola_0075 hypothetical protein; hypothetical protein 5761131 7116288 Mchl_5371 Methylobacterium extorquens CM4 hypothetical protein YP_002424057.1 5760487 R 440085 CDS YP_002424058.1 218533242 7116289 complement(5761142..5761774) 1 NC_011757.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: bov:BOV_0279 recombinase; Resolvase domain 5761774 7116289 Mchl_5372 Methylobacterium extorquens CM4 Resolvase domain YP_002424058.1 5761142 R 440085 CDS YP_002424059.1 218533243 7116290 5762226..5763923 1 NC_011757.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mex:Mext_0141 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 5763923 7116290 Mchl_5373 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002424059.1 5762226 D 440085 CDS YP_002424060.1 218533244 7116291 5763923..5764246 1 NC_011757.1 KEGG: mex:Mext_0140 hypothetical protein; hypothetical protein 5764246 7116291 Mchl_5374 Methylobacterium extorquens CM4 hypothetical protein YP_002424060.1 5763923 D 440085 CDS YP_002424061.1 218533245 7116292 5765018..5765281 1 NC_011757.1 KEGG: mpo:Mpop_0307 hypothetical protein; hypothetical protein 5765281 7116292 Mchl_5375 Methylobacterium extorquens CM4 hypothetical protein YP_002424061.1 5765018 D 440085 CDS YP_002424062.1 218533246 7116293 complement(5765382..5765702) 1 NC_011757.1 KEGG: mpo:Mpop_3310 hypothetical protein; hypothetical protein 5765702 7116293 Mchl_5376 Methylobacterium extorquens CM4 hypothetical protein YP_002424062.1 5765382 R 440085 CDS YP_002424063.1 218533247 7116294 complement(5766046..5767044) 1 NC_011757.1 PFAM: alpha/beta hydrolase fold; KEGG: mex:Mext_0102 alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 5767044 7116294 Mchl_5377 Methylobacterium extorquens CM4 alpha/beta hydrolase fold protein YP_002424063.1 5766046 R 440085 CDS YP_002424064.1 218533248 7116295 complement(5767281..5768150) 1 NC_011757.1 PFAM: integrase catalytic region; KEGG: mpo:Mpop_3817 integrase catalytic region; integrase catalytic subunit 5768150 7116295 Mchl_5378 Methylobacterium extorquens CM4 integrase catalytic subunit YP_002424064.1 5767281 R 440085 CDS YP_002424065.1 218533249 7116296 complement(5768189..5768464) 1 NC_011757.1 PFAM: transposase IS3/IS911 family protein; KEGG: mpo:Mpop_3816 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 5768464 7116296 Mchl_5379 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424065.1 5768189 R 440085 CDS YP_002424066.1 218533250 7116297 5768649..5771321 1 NC_011757.1 KEGG: mpo:Mpop_4105 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; multi-sensor hybrid histidine kinase 5771321 7116297 Mchl_5380 Methylobacterium extorquens CM4 multi-sensor hybrid histidine kinase YP_002424066.1 5768649 D 440085 CDS YP_002424067.1 218533251 7116298 complement(5771525..5773249) 1 NC_011757.1 PFAM: AMP-dependent synthetase and ligase; KEGG: azc:AZC_2874 AMP-dependent synthetase; AMP-dependent synthetase and ligase 5773249 7116298 Mchl_5381 Methylobacterium extorquens CM4 AMP-dependent synthetase and ligase YP_002424067.1 5771525 R 440085 CDS YP_002424068.1 218533252 7116299 5773394..5774368 1 NC_011757.1 hypothetical protein 5774368 7116299 Mchl_5382 Methylobacterium extorquens CM4 hypothetical protein YP_002424068.1 5773394 D 440085 CDS YP_002424069.1 218533253 7116300 5774365..5774952 1 NC_011757.1 hypothetical protein 5774952 7116300 Mchl_5383 Methylobacterium extorquens CM4 hypothetical protein YP_002424069.1 5774365 D 440085 CDS YP_002424070.1 218533254 7116301 complement(5775035..5775829) 1 NC_011757.1 KEGG: vei:Veis_3747 hypothetical protein; hypothetical protein 5775829 7116301 Mchl_5384 Methylobacterium extorquens CM4 hypothetical protein YP_002424070.1 5775035 R 440085 CDS YP_002424071.1 218533255 7116302 complement(5776005..5777804) 1 NC_011757.1 PFAM: integrase family protein; KEGG: ret:RHE_CH00241 recombinase protein, phage integrase family; integrase family protein 5777804 7116302 Mchl_5385 Methylobacterium extorquens CM4 integrase family protein YP_002424071.1 5776005 R 440085 CDS YP_002424072.1 218533257 7119086 44..1483 1 NC_011758.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: mrd:Mrad2831_5257 YVTN beta-propeller repeat-containing protein; 40-residue YVTN family beta-propeller repeat protein 1483 7119086 Mchl_5386 Methylobacterium extorquens CM4 40-residue YVTN family beta-propeller repeat protein YP_002424072.1 44 D 440085 CDS YP_002424073.1 218533258 7119087 complement(1533..1853) 1 NC_011758.1 KEGG: mrd:Mrad2831_4216 sulfite:cytochrome C oxidoreductase subunit B; sulfite:cytochrome C oxidoreductase subunit B 1853 7119087 Mchl_5387 Methylobacterium extorquens CM4 sulfite:cytochrome C oxidoreductase subunit B YP_002424073.1 1533 R 440085 CDS YP_002424074.1 218533259 7119088 complement(1867..3078) 1 NC_011758.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: mrd:Mrad2831_4215 oxidoreductase molybdopterin binding; oxidoreductase molybdopterin binding 3078 7119088 Mchl_5388 Methylobacterium extorquens CM4 oxidoreductase molybdopterin binding YP_002424074.1 1867 R 440085 CDS YP_002424075.1 218533260 7119089 complement(3198..3899) 1 NC_011758.1 KEGG: xau:Xaut_2673 transmembrane anti-sigma factor; transmembrane anti-sigma factor 3899 7119089 Mchl_5389 Methylobacterium extorquens CM4 transmembrane anti-sigma factor YP_002424075.1 3198 R 440085 CDS YP_002424076.1 218533261 7119090 complement(3899..4459) 1 NC_011758.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: xau:Xaut_2674 ECF subfamily RNA polymerase sigma-24 factor; RNA polymerase, sigma-24 subunit, ECF subfamily 4459 7119090 Mchl_5390 Methylobacterium extorquens CM4 RNA polymerase, sigma-24 subunit, ECF subfamily YP_002424076.1 3899 R 440085 CDS YP_002424077.1 218533262 7119091 complement(4842..6287) 1 NC_011758.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: mpo:Mpop_0054 GntR family transcriptional regulator with aminotransferase domain; GntR family transcriptional regulator 6287 7119091 Mchl_5391 Methylobacterium extorquens CM4 GntR family transcriptional regulator YP_002424077.1 4842 R 440085 CDS YP_002424078.1 218533263 7119092 6628..7110 1 NC_011758.1 KEGG: mpo:Mpop_0055 hypothetical protein; hypothetical protein 7110 7119092 Mchl_5392 Methylobacterium extorquens CM4 hypothetical protein YP_002424078.1 6628 D 440085 CDS YP_002424079.1 218533264 7119093 7191..8267 1 NC_011758.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mpo:Mpop_0056 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 8267 7119093 Mchl_5393 Methylobacterium extorquens CM4 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_002424079.1 7191 D 440085 CDS YP_002424080.1 218533265 7119094 8221..9324 1 NC_011758.1 PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mpo:Mpop_0057 radical SAM protein; radical SAM protein 9324 7119094 Mchl_5394 Methylobacterium extorquens CM4 radical SAM protein YP_002424080.1 8221 D 440085 CDS YP_002424081.1 218533266 7119095 9321..9866 1 NC_011758.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mpo:Mpop_0058 GCN5-related N-acetyltransferase; GCN5-related N-acetyltransferase 9866 7119095 Mchl_5395 Methylobacterium extorquens CM4 GCN5-related N-acetyltransferase YP_002424081.1 9321 D 440085 CDS YP_002424082.1 218533267 7119096 9866..10861 1 NC_011758.1 PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mpo:Mpop_0059 AIR synthase related protein; AIR synthase related protein 10861 7119096 Mchl_5396 Methylobacterium extorquens CM4 AIR synthase related protein YP_002424082.1 9866 D 440085 CDS YP_002424083.1 218533268 7119097 10858..12033 1 NC_011758.1 PFAM: glycosyl transferase group 1; KEGG: mpo:Mpop_0061 glycosyl transferase group 1; glycosyl transferase group 1 12033 7119097 Mchl_5397 Methylobacterium extorquens CM4 glycosyl transferase group 1 YP_002424083.1 10858 D 440085 CDS YP_002424084.1 218533269 7119098 12026..12307 1 NC_011758.1 KEGG: mpo:Mpop_0062 hypothetical protein; hypothetical protein 12307 7119098 Mchl_5398 Methylobacterium extorquens CM4 hypothetical protein YP_002424084.1 12026 D 440085 CDS YP_002424085.1 218533270 7119099 12346..13614 1 NC_011758.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mpo:Mpop_0063 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase 13614 7119099 Mchl_5399 Methylobacterium extorquens CM4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_002424085.1 12346 D 440085 CDS YP_002424086.1 218533271 7119100 13894..14505 1 NC_011758.1 PFAM: cobalamin synthesis CobW domain protein; KEGG: mrd:Mrad2831_0862 cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein 14505 7119100 Mchl_5400 Methylobacterium extorquens CM4 cobalamin synthesis CobW domain protein YP_002424086.1 13894 D 440085 CDS YP_002424087.1 218533272 7119101 15580..15933 1 NC_011758.1 hypothetical protein 15933 7119101 Mchl_5401 Methylobacterium extorquens CM4 hypothetical protein YP_002424087.1 15580 D 440085 CDS YP_002424088.1 218533273 7119102 16058..16516 1 NC_011758.1 KEGG: rpt:Rpal_1148 hypothetical protein; hypothetical protein 16516 7119102 Mchl_5402 Methylobacterium extorquens CM4 hypothetical protein YP_002424088.1 16058 D 440085 CDS YP_002424089.1 218533274 7119103 17416..18255 1 NC_011758.1 PFAM: resolvase; Recombinase; KEGG: nha:Nham_3864 recombinase; resolvase 18255 7119103 Mchl_5403 Methylobacterium extorquens CM4 resolvase YP_002424089.1 17416 D 440085 CDS YP_002424090.1 218533275 7119104 18620..20836 1 NC_011758.1 PFAM: resolvase; Recombinase; KEGG: mpo:Mpop_3842 resolvase domain; Recombinase 20836 7119104 Mchl_5404 Methylobacterium extorquens CM4 Recombinase YP_002424090.1 18620 D 440085 CDS YP_002424091.1 218533276 7119105 complement(20860..22173) 1 NC_011758.1 PFAM: chloride channel core; KEGG: met:M446_6166 chloride channel core; chloride channel core 22173 7119105 Mchl_5405 Methylobacterium extorquens CM4 chloride channel core YP_002424091.1 20860 R 440085 CDS YP_002424092.1 218533277 7119106 complement(22845..23594) 1 NC_011758.1 SMART: TIR protein; KEGG: mex:Mext_1920 TIR protein; TIR protein 23594 7119106 Mchl_5406 Methylobacterium extorquens CM4 TIR protein YP_002424092.1 22845 R 440085 CDS YP_002424093.1 218533278 7119107 complement(23597..23758) 1 NC_011758.1 hypothetical protein 23758 7119107 Mchl_5407 Methylobacterium extorquens CM4 hypothetical protein YP_002424093.1 23597 R 440085 CDS YP_002424094.1 218533279 7119108 complement(24059..25825) 1 NC_011758.1 KEGG: cbk:CLL_A2630 sec-C motif domain protein; hypothetical protein 25825 7119108 Mchl_5408 Methylobacterium extorquens CM4 hypothetical protein YP_002424094.1 24059 R 440085 CDS YP_002424095.1 218533280 7119109 complement(25970..26215) 1 NC_011758.1 hypothetical protein 26215 7119109 Mchl_5409 Methylobacterium extorquens CM4 hypothetical protein YP_002424095.1 25970 R 440085 CDS YP_002424096.1 218533281 7119111 complement(27357..29516) 1 NC_011758.1 PFAM: protein of unknown function DUF323; KEGG: sco:SCO0305 hypothetical protein; hypothetical protein 29516 7119111 Mchl_5411 Methylobacterium extorquens CM4 hypothetical protein YP_002424096.1 27357 R 440085 CDS YP_002424097.1 218533282 7119195 complement(29628..32981) 1 NC_011758.1 PFAM: UvrD/REP helicase; KEGG: rpa:RPA2215 ATP-dependent exodeoxyribonuclease (subunit A); UvrD/REP helicase 32981 7119195 Mchl_5412 Methylobacterium extorquens CM4 UvrD/REP helicase YP_002424097.1 29628 R 440085 CDS YP_002424098.1 218533283 7119196 complement(32981..35641) 1 NC_011758.1 KEGG: xau:Xaut_2986 hypothetical protein; hypothetical protein 35641 7119196 Mchl_5413 Methylobacterium extorquens CM4 hypothetical protein YP_002424098.1 32981 R 440085 CDS YP_002424099.1 218533284 7119197 complement(35914..38181) 1 NC_011758.1 PFAM: helicase; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: rpe:RPE_2448 DEAD/DEAH box helicase; DEAD/DEAH box helicase 38181 7119197 Mchl_5414 Methylobacterium extorquens CM4 DEAD/DEAH box helicase YP_002424099.1 35914 R 440085 CDS YP_002424100.1 218533285 7119198 complement(38156..39481) 1 NC_011758.1 KEGG: rpb:RPB_2542 hypothetical protein; hypothetical protein 39481 7119198 Mchl_5415 Methylobacterium extorquens CM4 hypothetical protein YP_002424100.1 38156 R 440085 CDS YP_002424101.1 218533286 7119199 complement(39487..41730) 1 NC_011758.1 KEGG: nha:Nham_2000 hypothetical protein; hypothetical protein 41730 7119199 Mchl_5416 Methylobacterium extorquens CM4 hypothetical protein YP_002424101.1 39487 R 440085 CDS YP_002424102.1 218533287 7119200 complement(41684..42637) 1 NC_011758.1 KEGG: LOC771139; hypothetical protein LOC771139; hypothetical protein 42637 7119200 Mchl_5417 Methylobacterium extorquens CM4 hypothetical protein YP_002424102.1 41684 R 440085 CDS YP_002424103.1 218533288 7119201 complement(42687..43184) 1 NC_011758.1 hypothetical protein 43184 7119201 Mchl_5418 Methylobacterium extorquens CM4 hypothetical protein YP_002424103.1 42687 R 440085 CDS YP_002424104.1 218533289 7119202 complement(43297..43812) 1 NC_011758.1 hypothetical protein 43812 7119202 Mchl_5419 Methylobacterium extorquens CM4 hypothetical protein YP_002424104.1 43297 R 440085 CDS YP_002424105.1 218533290 7119203 44996..45385 1 NC_011758.1 hypothetical protein 45385 7119203 Mchl_5420 Methylobacterium extorquens CM4 hypothetical protein YP_002424105.1 44996 D 440085 CDS YP_002424106.1 218533291 7119204 46428..46925 1 NC_011758.1 hypothetical protein 46925 7119204 Mchl_5421 Methylobacterium extorquens CM4 hypothetical protein YP_002424106.1 46428 D 440085 CDS YP_002424107.1 218533292 7119207 complement(48133..48327) 1 NC_011758.1 hypothetical protein 48327 7119207 Mchl_5424 Methylobacterium extorquens CM4 hypothetical protein YP_002424107.1 48133 R 440085 CDS YP_002424108.1 218533293 7119208 complement(48328..49563) 1 NC_011758.1 KEGG: rle:pRL100078 hypothetical protein; hypothetical protein 49563 7119208 Mchl_5425 Methylobacterium extorquens CM4 hypothetical protein YP_002424108.1 48328 R 440085 CDS YP_002424109.1 218533294 7119209 49705..49989 1 NC_011758.1 hypothetical protein 49989 7119209 Mchl_5426 Methylobacterium extorquens CM4 hypothetical protein YP_002424109.1 49705 D 440085 CDS YP_002424110.1 218533295 7119210 complement(49964..50875) 1 NC_011758.1 hypothetical protein 50875 7119210 Mchl_5427 Methylobacterium extorquens CM4 hypothetical protein YP_002424110.1 49964 R 440085 CDS YP_002424111.1 218533296 7119211 complement(51152..52996) 1 NC_011758.1 PFAM: alpha amylase; SMART: alpha amylase catalytic sub domain; KEGG: mba:Mbar_A1790 alpha-amylase; alpha amylase 52996 7119211 Mchl_5428 Methylobacterium extorquens CM4 alpha amylase YP_002424111.1 51152 R 440085 CDS YP_002424112.1 218533297 7119212 complement(53292..54203) 1 NC_011758.1 KEGG: rsq:Rsph17025_4384 hypothetical protein; hypothetical protein 54203 7119212 Mchl_5429 Methylobacterium extorquens CM4 hypothetical protein YP_002424112.1 53292 R 440085 CDS YP_002424113.1 218533298 7119213 complement(54238..55821) 1 NC_011758.1 KEGG: rsq:Rsph17025_4383 type I restriction-modification system methyltransferase subunit-like protein; type I restriction-modification system methyltransferase subunit-like protein 55821 7119213 Mchl_5430 Methylobacterium extorquens CM4 type I restriction-modification system methyltransferase subunit-like protein YP_002424113.1 54238 R 440085 CDS YP_002424114.1 218533299 7119214 56175..57365 1 NC_011758.1 KEGG: rha:RHA1_ro09119 hypothetical protein; hypothetical protein 57365 7119214 Mchl_5431 Methylobacterium extorquens CM4 hypothetical protein YP_002424114.1 56175 D 440085 CDS YP_002424115.1 218533300 7119215 57362..58309 1 NC_011758.1 KEGG: rfr:Rfer_1067 hypothetical protein; hypothetical protein 58309 7119215 Mchl_5432 Methylobacterium extorquens CM4 hypothetical protein YP_002424115.1 57362 D 440085 CDS YP_002424116.1 218533301 7119216 58625..59275 1 NC_011758.1 PFAM: Domain of unknown function DUF1863; KEGG: pca:Pcar_2917 hypothetical protein; hypothetical protein 59275 7119216 Mchl_5433 Methylobacterium extorquens CM4 hypothetical protein YP_002424116.1 58625 D 440085 CDS YP_002424117.1 218533302 7119217 59646..60887 1 NC_011758.1 SMART: TIR protein; KEGG: nwi:Nwi_0257 hypothetical protein; TIR protein 60887 7119217 Mchl_5434 Methylobacterium extorquens CM4 TIR protein YP_002424117.1 59646 D 440085 CDS YP_002424118.1 218533303 7119219 61517..62251 1 NC_011758.1 PFAM: protein of unknown function DUF1275; KEGG: mpo:Mpop_2916 protein of unknown function DUF1275; hypothetical protein 62251 7119219 Mchl_5436 Methylobacterium extorquens CM4 hypothetical protein YP_002424118.1 61517 D 440085 CDS YP_002424119.1 218533304 7119220 complement(62546..63961) 1 NC_011758.1 PFAM: integrase; KEGG: mpo:Mpop_2395 integrase; integrase 63961 7119220 Mchl_5437 Methylobacterium extorquens CM4 integrase YP_002424119.1 62546 R 440085 CDS YP_002424120.1 218533305 7119222 complement(64860..66080) 1 NC_011758.1 PFAM: transposase mutator type; KEGG: nha:Nham_3015 transposase, mutator type; transposase mutator type 66080 7119222 Mchl_5439 Methylobacterium extorquens CM4 transposase mutator type YP_002424120.1 64860 R 440085 CDS YP_002424121.1 218533306 7119223 complement(66102..66836) 1 NC_011758.1 PFAM: transposase IS111A/IS1328/IS1533; KEGG: mex:Mext_3686 transposase IS116/IS110/IS902 family protein; transposase IS111A/IS1328/IS1533 66836 7119223 Mchl_5440 Methylobacterium extorquens CM4 transposase IS111A/IS1328/IS1533 YP_002424121.1 66102 R 440085 CDS YP_002424122.1 218533307 7119224 67086..68285 1 NC_011758.1 PFAM: transposase mutator type; KEGG: met:M446_7018 hypothetical protein; transposase mutator type 68285 7119224 Mchl_5441 Methylobacterium extorquens CM4 transposase mutator type YP_002424122.1 67086 D 440085 CDS YP_002424123.1 218533308 7119227 complement(69469..71268) 1 NC_011758.1 TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: pyrrolo-quinoline quinone; KEGG: mex:Mext_1809 methanol/ethanol family PQQ-dependent dehydrogenase; PQQ-dependent dehydrogenase, methanol/ethanol family 71268 7119227 Mchl_5444 Methylobacterium extorquens CM4 PQQ-dependent dehydrogenase, methanol/ethanol family YP_002424123.1 69469 R 440085 CDS YP_002424124.1 218533309 7119228 71459..72895 1 NC_011758.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: bbt:BBta_5349 two-component sensor histidine kinase; histidine kinase 72895 7119228 Mchl_5445 Methylobacterium extorquens CM4 histidine kinase YP_002424124.1 71459 D 440085 CDS YP_002424125.1 218533310 7119229 72892..73548 1 NC_011758.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: mpo:Mpop_3468 two component transcriptional regulator, LuxR family; LuxR family transcriptional regulator 73548 7119229 Mchl_5446 Methylobacterium extorquens CM4 LuxR family transcriptional regulator YP_002424125.1 72892 D 440085 CDS YP_002424126.1 218533311 7119230 complement(73838..74671) 1 NC_011758.1 PFAM: integrase; KEGG: nwi:Nwi_2918 integrase, catalytic region; integrase 74671 7119230 Mchl_5447 Methylobacterium extorquens CM4 integrase YP_002424126.1 73838 R 440085 CDS YP_002424127.1 218533312 7119231 complement(74749..75639) 1 NC_011758.1 PFAM: integrase; KEGG: gdi:GDI0980 integrase; integrase 75639 7119231 Mchl_5448 Methylobacterium extorquens CM4 integrase YP_002424127.1 74749 R 440085 CDS YP_002424128.1 218533313 7119232 complement(75636..75920) 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: sal:Sala_0416 transposase IS3/IS911; transposase IS3/IS911 family protein 75920 7119232 Mchl_5449 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424128.1 75636 R 440085 CDS YP_002424129.1 218533314 7119234 complement(76970..77950) 1 NC_011758.1 PFAM: integrase; transposase IS3/IS911 family protein; KEGG: nwi:Nwi_3112 helix-turn-helix, fis-type; integrase 77950 7119234 Mchl_5451 Methylobacterium extorquens CM4 integrase YP_002424129.1 76970 R 440085 CDS YP_002424130.1 218533315 7119235 complement(77947..78321) 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_3087 transposase; transposase IS3/IS911 family protein 78321 7119235 Mchl_5452 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424130.1 77947 R 440085 CDS YP_002424131.1 218533316 7119236 78681..79760 1 NC_011758.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: ecp:ECP_4551 transposase; transposase IS116/IS110/IS902 family protein 79760 7119236 Mchl_5453 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002424131.1 78681 D 440085 CDS YP_002424132.1 218533317 7119238 complement(80197..81336) 1 NC_011758.1 PFAM: CBS domain containing protein; HPP family protein; KEGG: mex:Mext_2087 HPP family protein?; hypothetical protein 81336 7119238 Mchl_5455 Methylobacterium extorquens CM4 hypothetical protein YP_002424132.1 80197 R 440085 CDS YP_002424133.1 218533318 7119239 81523..81843 1 NC_011758.1 hypothetical protein 81843 7119239 Mchl_5456 Methylobacterium extorquens CM4 hypothetical protein YP_002424133.1 81523 D 440085 CDS YP_002424134.1 218533319 7119240 complement(82319..82855) 1 NC_011758.1 KEGG: mex:Mext_2817 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 82855 7119240 Mchl_5457 Methylobacterium extorquens CM4 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002424134.1 82319 R 440085 CDS YP_002424135.1 218533320 7119241 complement(82852..83814) 1 NC_011758.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: mlo:mlr2177 hypothetical protein; pseudouridine synthase 83814 7119241 Mchl_5458 Methylobacterium extorquens CM4 pseudouridine synthase YP_002424135.1 82852 R 440085 CDS YP_002424136.1 218533321 7119242 complement(83825..85087) 1 NC_011758.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: oan:Oant_0300 Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase 85087 7119242 Mchl_5459 Methylobacterium extorquens CM4 Glu/Leu/Phe/Val dehydrogenase YP_002424136.1 83825 R 440085 CDS YP_002424137.1 218533322 7119243 complement(85214..86371) 1 NC_011758.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 86371 7119243 Mchl_5460 Methylobacterium extorquens CM4 phosphoserine aminotransferase YP_002424137.1 85214 R 440085 CDS YP_002424138.1 218533323 7119244 complement(86455..87714) 1 NC_011758.1 TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; KEGG: mpo:Mpop_1834 squalene-associated FAD-dependent desaturase; squalene-associated FAD-dependent desaturase 87714 7119244 Mchl_5461 Methylobacterium extorquens CM4 squalene-associated FAD-dependent desaturase YP_002424138.1 86455 R 440085 CDS YP_002424139.1 218533324 7119245 complement(87722..89158) 1 NC_011758.1 PFAM: homospermidine synthase; KEGG: mex:Mext_2042 homospermidine synthase; homospermidine synthase 89158 7119245 Mchl_5462 Methylobacterium extorquens CM4 homospermidine synthase YP_002424139.1 87722 R 440085 CDS YP_002424140.1 218533325 7119246 complement(89257..89706) 1 NC_011758.1 KEGG: mex:Mext_3358 hypothetical protein; GreA/GreB family elongation factor 89706 7119246 Mchl_5463 Methylobacterium extorquens CM4 GreA/GreB family elongation factor YP_002424140.1 89257 R 440085 CDS YP_002424141.1 218533326 7119247 90596..91009 1 NC_011758.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: mpo:Mpop_4181 GreA/GreB family elongation factor; GreA/GreB family elongation factor 91009 7119247 Mchl_5464 Methylobacterium extorquens CM4 GreA/GreB family elongation factor YP_002424141.1 90596 D 440085 CDS YP_002424142.1 218533327 7119249 complement(93094..93348) 1 NC_011758.1 hypothetical protein 93348 7119249 Mchl_5466 Methylobacterium extorquens CM4 hypothetical protein YP_002424142.1 93094 R 440085 CDS YP_002424143.1 218533328 7119250 complement(93602..94045) 1 NC_011758.1 KEGG: noc:Noc_1918 transcription elongation factor; GreA/GreB family elongation factor 94045 7119250 Mchl_5467 Methylobacterium extorquens CM4 GreA/GreB family elongation factor YP_002424143.1 93602 R 440085 CDS YP_002424144.1 218533329 7119251 complement(94073..94495) 1 NC_011758.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: mex:Mext_3357 transcription elongation factor GreA/GreB domain-containing protein; GreA/GreB family elongation factor 94495 7119251 Mchl_5468 Methylobacterium extorquens CM4 GreA/GreB family elongation factor YP_002424144.1 94073 R 440085 CDS YP_002424145.1 218533330 7119252 complement(94511..94663) 1 NC_011758.1 hypothetical protein 94663 7119252 Mchl_5469 Methylobacterium extorquens CM4 hypothetical protein YP_002424145.1 94511 R 440085 CDS YP_002424146.1 218533331 7119253 95293..95532 1 NC_011758.1 hypothetical protein 95532 7119253 Mchl_5470 Methylobacterium extorquens CM4 hypothetical protein YP_002424146.1 95293 D 440085 CDS YP_002424147.1 218533332 7119254 96233..96430 1 NC_011758.1 hypothetical protein 96430 7119254 Mchl_5471 Methylobacterium extorquens CM4 hypothetical protein YP_002424147.1 96233 D 440085 CDS YP_002424148.1 218533333 7119255 96470..97399 1 NC_011758.1 PFAM: UspA domain protein; KEGG: pla:Plav_3480 UspA domain-containing protein; UspA domain protein 97399 7119255 Mchl_5472 Methylobacterium extorquens CM4 UspA domain protein YP_002424148.1 96470 D 440085 CDS YP_002424149.1 218533334 7119256 97460..98110 1 NC_011758.1 KEGG: mpo:Mpop_3736 sigma 54 modulation protein/ribosomal protein S30EA; hypothetical protein 98110 7119256 Mchl_5473 Methylobacterium extorquens CM4 hypothetical protein YP_002424149.1 97460 D 440085 CDS YP_002424150.1 218533335 7119257 98107..98304 1 NC_011758.1 hypothetical protein 98304 7119257 Mchl_5474 Methylobacterium extorquens CM4 hypothetical protein YP_002424150.1 98107 D 440085 CDS YP_002424151.1 218533336 7119262 join(100233..100724,100724..101293) 1 NC_011758.1 KEGG: rle:pRL70033 hypothetical protein; transposase 101293 7119262 Mchl_5479 Methylobacterium extorquens CM4 transposase YP_002424151.1 100233 D 440085 CDS YP_002424152.1 218533337 7119263 101486..105400 1 NC_011758.1 KEGG: rru:Rru_A0502 hypothetical protein; hypothetical protein 105400 7119263 Mchl_5480 Methylobacterium extorquens CM4 hypothetical protein YP_002424152.1 101486 D 440085 CDS YP_002424153.1 218533338 7119266 106307..106774 1 NC_011758.1 KEGG: gdi:GDI2860 integrase; integrase 106774 7119266 Mchl_5483 Methylobacterium extorquens CM4 integrase YP_002424153.1 106307 D 440085 CDS YP_002424154.1 218533339 7119267 106971..107255 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: sal:Sala_0416 transposase IS3/IS911; transposase IS3/IS911 family protein 107255 7119267 Mchl_5484 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424154.1 106971 D 440085 CDS YP_002424155.1 218533340 7119268 107252..108142 1 NC_011758.1 PFAM: integrase; KEGG: gdi:GDI0980 integrase; integrase 108142 7119268 Mchl_5485 Methylobacterium extorquens CM4 integrase YP_002424155.1 107252 D 440085 CDS YP_002424156.1 218533341 7119269 108226..108474 1 NC_011758.1 KEGG: mrd:Mrad2831_6417 resolvase domain-containing protein; hypothetical protein 108474 7119269 Mchl_5486 Methylobacterium extorquens CM4 hypothetical protein YP_002424156.1 108226 D 440085 CDS YP_002424157.1 218533342 7119270 complement(108477..109943) 1 NC_011758.1 KEGG: nwi:Nwi_3121 hypothetical protein; hypothetical protein 109943 7119270 Mchl_5487 Methylobacterium extorquens CM4 hypothetical protein YP_002424157.1 108477 R 440085 CDS YP_002424158.1 218533343 7119271 complement(110278..112821) 1 NC_011758.1 KEGG: nwi:Nwi_2088 hypothetical protein; hypothetical protein 112821 7119271 Mchl_5488 Methylobacterium extorquens CM4 hypothetical protein YP_002424158.1 110278 R 440085 CDS YP_002424159.1 218533344 7119272 complement(112874..113884) 1 NC_011758.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: met:M446_0961 ATPase central domain-containing protein; ATPase AAA 113884 7119272 Mchl_5489 Methylobacterium extorquens CM4 ATPase AAA YP_002424159.1 112874 R 440085 CDS YP_002424160.1 218533345 7119274 complement(116385..118322) 1 NC_011758.1 TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: prenyltransferase/squalene oxidase; KEGG: gbe:GbCGDNIH1_2107 squalene--hopene cyclase; squalene-hopene cyclase 118322 7119274 Mchl_5491 Methylobacterium extorquens CM4 squalene-hopene cyclase YP_002424160.1 116385 R 440085 CDS YP_002424161.1 218533346 7119275 complement(118428..118961) 1 NC_011758.1 PFAM: regulatory protein TetR; KEGG: mrd:Mrad2831_0286 TetR family transcriptional regulator; TetR family transcriptional regulator 118961 7119275 Mchl_5492 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002424161.1 118428 R 440085 CDS YP_002424162.1 218533347 7119276 119117..119461 1 NC_011758.1 PFAM: small multidrug resistance protein; KEGG: hne:HNE_0908 SMR family multidrug efflux pump; small multidrug resistance protein 119461 7119276 Mchl_5493 Methylobacterium extorquens CM4 small multidrug resistance protein YP_002424162.1 119117 D 440085 CDS YP_002424163.1 218533348 7119194 119464..119889 1 NC_011758.1 PFAM: regulatory protein TetR; KEGG: rpd:RPD_3328 regulatory protein, TetR; TetR family transcriptional regulator 119889 7119194 Mchl_5494 Methylobacterium extorquens CM4 TetR family transcriptional regulator YP_002424163.1 119464 D 440085 CDS YP_002424164.1 218533349 7119277 120081..121235 1 NC_011758.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: mrd:Mrad2831_0285 RND family efflux transporter MFP subunit; efflux transporter RND family, MFP subunit 121235 7119277 Mchl_5495 Methylobacterium extorquens CM4 efflux transporter RND family, MFP subunit YP_002424164.1 120081 D 440085 CDS YP_002424165.1 218533350 7119278 121255..124416 1 NC_011758.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mrd:Mrad2831_0284 hydrophobe/amphiphile efflux-1 (HAE1) family protein; transporter hydrophobe/amphiphile efflux-1 (HAE1) family 124416 7119278 Mchl_5496 Methylobacterium extorquens CM4 transporter hydrophobe/amphiphile efflux-1 (HAE1) family YP_002424165.1 121255 D 440085 CDS YP_002424166.1 218533351 7119280 complement(125326..127356) 1 NC_011758.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mpo:Mpop_3694 integral membrane sensor signal transduction histidine kinase; histidine kinase 127356 7119280 Mchl_5498 Methylobacterium extorquens CM4 histidine kinase YP_002424166.1 125326 R 440085 CDS YP_002424167.1 218533352 7119281 complement(127344..128714) 1 NC_011758.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: mpo:Mpop_3695 two component, sigma54 specific, transcriptional regulator, fis family; Fis family transcriptional regulator 128714 7119281 Mchl_5499 Methylobacterium extorquens CM4 Fis family transcriptional regulator YP_002424167.1 127344 R 440085 CDS YP_002424168.1 218533353 7119282 complement(128844..130481) 1 NC_011758.1 PFAM: major facilitator superfamily MFS_1; KEGG: mpo:Mpop_3696 major facilitator superfamily MFS_1; major facilitator superfamily MFS_1 130481 7119282 Mchl_5500 Methylobacterium extorquens CM4 major facilitator superfamily MFS_1 YP_002424168.1 128844 R 440085 CDS YP_002424169.1 218533354 7119283 130967..133162 1 NC_011758.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mpo:Mpop_3697 TonB-dependent receptor; TonB-dependent receptor 133162 7119283 Mchl_5501 Methylobacterium extorquens CM4 TonB-dependent receptor YP_002424169.1 130967 D 440085 CDS YP_002424170.1 218533355 7119284 join(133327..133644,133644..134093) 1 NC_011758.1 KEGG: mex:Mext_0768 transposase; hypothetical protein 134093 7119284 Mchl_5502 Methylobacterium extorquens CM4 hypothetical protein YP_002424170.1 133327 D 440085 CDS YP_002424171.1 218533356 7119285 134214..134600 1 NC_011758.1 KEGG: mpo:Mpop_3698 hypothetical protein; hypothetical protein 134600 7119285 Mchl_5503 Methylobacterium extorquens CM4 hypothetical protein YP_002424171.1 134214 D 440085 CDS YP_002424172.1 218533357 7119286 134597..135490 1 NC_011758.1 PFAM: Di-haem cytochrome C peroxidase; KEGG: mpo:Mpop_3699 cytochrome-c peroxidase; Di-heme cytochrome C peroxidase 135490 7119286 Mchl_5504 Methylobacterium extorquens CM4 Di-heme cytochrome C peroxidase YP_002424172.1 134597 D 440085 CDS YP_002424173.1 218533358 7119287 complement(135543..136523) 1 NC_011758.1 PFAM: integrase; transposase IS3/IS911 family protein; KEGG: nwi:Nwi_3112 helix-turn-helix, fis-type; integrase 136523 7119287 Mchl_5505 Methylobacterium extorquens CM4 integrase YP_002424173.1 135543 R 440085 CDS YP_002424174.1 218533359 7119288 complement(136520..136894) 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_3087 transposase; transposase IS3/IS911 family protein 136894 7119288 Mchl_5506 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424174.1 136520 R 440085 CDS YP_002424175.1 218533360 7119289 137274..137627 1 NC_011758.1 KEGG: mrd:Mrad2831_6176 hypothetical protein; hypothetical protein 137627 7119289 Mchl_5507 Methylobacterium extorquens CM4 hypothetical protein YP_002424175.1 137274 D 440085 CDS YP_002424176.1 218533361 7119290 complement(137680..138192) 1 NC_011758.1 KEGG: azc:AZC_3125 hypothetical protein; hypothetical protein 138192 7119290 Mchl_5508 Methylobacterium extorquens CM4 hypothetical protein YP_002424176.1 137680 R 440085 CDS YP_002424177.1 218533362 7119291 complement(138597..139586) 1 NC_011758.1 KEGG: mpo:Mpop_3704 hypothetical protein; hypothetical protein 139586 7119291 Mchl_5509 Methylobacterium extorquens CM4 hypothetical protein YP_002424177.1 138597 R 440085 CDS YP_002424178.1 218533363 7119292 complement(139688..140941) 1 NC_011758.1 KEGG: mpo:Mpop_3705 hypothetical protein; hypothetical protein 140941 7119292 Mchl_5510 Methylobacterium extorquens CM4 hypothetical protein YP_002424178.1 139688 R 440085 CDS YP_002424179.1 218533364 7119293 complement(141034..141378) 1 NC_011758.1 TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein LysR; KEGG: mpo:Mpop_3706 ModE family transcriptional regulator; ModE family transcriptional regulator 141378 7119293 Mchl_5511 Methylobacterium extorquens CM4 ModE family transcriptional regulator YP_002424179.1 141034 R 440085 CDS YP_002424180.1 218533365 7119294 complement(141474..142742) 1 NC_011758.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mpo:Mpop_3707 molybdenum cofactor synthesis domain protein; molybdenum cofactor synthesis protein 142742 7119294 Mchl_5512 Methylobacterium extorquens CM4 molybdenum cofactor synthesis protein YP_002424180.1 141474 R 440085 CDS YP_002424181.1 218533366 7119295 142862..143917 1 NC_011758.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: gdi:GDI2530 NADP-dependent alcohol dehydrogenase C; alcohol dehydrogenase zinc-binding domain protein 143917 7119295 Mchl_5513 Methylobacterium extorquens CM4 alcohol dehydrogenase zinc-binding domain protein YP_002424181.1 142862 D 440085 CDS YP_002424182.1 218533367 7119296 143954..144751 1 NC_011758.1 TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: mpo:Mpop_3709 molybdenum ABC transporter periplasmic molybdate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 144751 7119296 Mchl_5514 Methylobacterium extorquens CM4 molybdenum ABC transporter periplasmic molybdate-binding protein YP_002424182.1 143954 D 440085 CDS YP_002424183.1 218533368 7119297 144748..145440 1 NC_011758.1 TIGRFAM: molybdate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: mpo:Mpop_3710 molybdate ABC transporter inner membrane subunit; molybdate ABC transporter inner membrane subunit 145440 7119297 Mchl_5515 Methylobacterium extorquens CM4 molybdate ABC transporter inner membrane subunit YP_002424183.1 144748 D 440085 CDS YP_002424184.1 218533369 7119298 145468..146544 1 NC_011758.1 KEGG: mpo:Mpop_3711 molybdate ABC transporter ATPase subunit; TIGRFAM: molybdate ABC transporter ATPase; PFAM: ABC transporter related; TOBE domain protein; SMART: ATPase AAA; molybdate ABC transporter ATPase 146544 7119298 Mchl_5516 Methylobacterium extorquens CM4 molybdate ABC transporter ATPase YP_002424184.1 145468 D 440085 CDS YP_002424185.1 218533370 7119299 146704..146913 1 NC_011758.1 PFAM: TOBE domain protein; KEGG: mpo:Mpop_3712 TOBE domain protein; TOBE domain protein 146913 7119299 Mchl_5517 Methylobacterium extorquens CM4 TOBE domain protein YP_002424185.1 146704 D 440085 CDS YP_002424186.1 218533371 7119301 147418..148011 1 NC_011758.1 PFAM: resolvase; Resolvase helix-turn-helix domain protein; KEGG: mrd:Mrad2831_6417 resolvase domain-containing protein; resolvase 148011 7119301 Mchl_5519 Methylobacterium extorquens CM4 resolvase YP_002424186.1 147418 D 440085 CDS YP_002424187.1 218533372 7119302 complement(148125..148979) 1 NC_011758.1 KEGG: mrd:Mrad2831_5044 hypothetical protein; hypothetical protein 148979 7119302 Mchl_5520 Methylobacterium extorquens CM4 hypothetical protein YP_002424187.1 148125 R 440085 CDS YP_002424188.1 218533373 7119303 complement(149203..149712) 1 NC_011758.1 PFAM: acetone carboxylase subunit gamma; KEGG: azc:AZC_2921 acetone carboxylase subunit gamma; acetone carboxylase subunit gamma 149712 7119303 Mchl_5521 Methylobacterium extorquens CM4 acetone carboxylase subunit gamma YP_002424188.1 149203 R 440085 CDS YP_002424189.1 218533374 7119304 complement(149801..152131) 1 NC_011758.1 PFAM: hydantoinase B/oxoprolinase; KEGG: azc:AZC_2922 acetone carboxylase subunit alpha; hydantoinase B/oxoprolinase 152131 7119304 Mchl_5522 Methylobacterium extorquens CM4 hydantoinase B/oxoprolinase YP_002424189.1 149801 R 440085 CDS YP_002424190.1 218533375 7119305 complement(152169..154322) 1 NC_011758.1 PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: azc:AZC_2923 acetone carboxylase subunit beta; 5-oxoprolinase (ATP-hydrolyzing) 154322 7119305 Mchl_5523 Methylobacterium extorquens CM4 5-oxoprolinase (ATP-hydrolyzing) YP_002424190.1 152169 R 440085 CDS YP_002424191.1 218533376 7119306 complement(154558..156480) 1 NC_011758.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: azc:AZC_2924 sigma54 specific transcriptional regulator; GAF modulated sigma54 specific transcriptional regulator, Fis family 156480 7119306 Mchl_5524 Methylobacterium extorquens CM4 GAF modulated sigma54 specific transcriptional regulator, Fis family YP_002424191.1 154558 R 440085 CDS YP_002424192.1 218533377 7119308 complement(157559..158341) 1 NC_011758.1 PFAM: integrase; KEGG: bcj:BCAM1952 transposase; integrase 158341 7119308 Mchl_5526 Methylobacterium extorquens CM4 integrase YP_002424192.1 157559 R 440085 CDS YP_002424193.1 218533378 7119309 complement(158392..158658) 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: dde:Dde_2906 Fis family transcriptional regulator; transposase IS3/IS911 family protein 158658 7119309 Mchl_5527 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424193.1 158392 R 440085 CDS YP_002424194.1 218533379 7119310 158724..159278 1 NC_011758.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mpo:Mpop_1933 response regulator receiver modulated diguanylate cyclase; diguanylate cyclase 159278 7119310 Mchl_5528 Methylobacterium extorquens CM4 diguanylate cyclase YP_002424194.1 158724 D 440085 CDS YP_002424195.1 218533380 7119311 complement(159275..159697) 1 NC_011758.1 KEGG: mrd:Mrad2831_6409 hypothetical protein; hypothetical protein 159697 7119311 Mchl_5529 Methylobacterium extorquens CM4 hypothetical protein YP_002424195.1 159275 R 440085 CDS YP_002424196.1 218533381 7119312 159975..160145 1 NC_011758.1 KEGG: mlo:msr9708 hypothetical protein; hypothetical protein 160145 7119312 Mchl_5530 Methylobacterium extorquens CM4 hypothetical protein YP_002424196.1 159975 D 440085 CDS YP_002424197.1 218533382 7119313 160360..160872 1 NC_011758.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mrd:Mrad2831_4324 MucR family transcriptional regulator; MucR family transcriptional regulator 160872 7119313 Mchl_5531 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002424197.1 160360 D 440085 CDS YP_002424198.1 218533383 7119314 161423..161740 1 NC_011758.1 PFAM: protein of unknown function DUF736; KEGG: pde:Pden_1518 protein of unknown function DUF736; hypothetical protein 161740 7119314 Mchl_5532 Methylobacterium extorquens CM4 hypothetical protein YP_002424198.1 161423 D 440085 CDS YP_002424199.1 218533384 7119315 161810..162067 1 NC_011758.1 KEGG: rpc:RPC_2516 hypothetical protein; hypothetical protein 162067 7119315 Mchl_5533 Methylobacterium extorquens CM4 hypothetical protein YP_002424199.1 161810 D 440085 CDS YP_002424200.1 218533385 7119316 complement(162217..162936) 1 NC_011758.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: rba:RB4967 DeoR family transcriptional regulator; hypothetical protein 162936 7119316 Mchl_5534 Methylobacterium extorquens CM4 hypothetical protein YP_002424200.1 162217 R 440085 CDS YP_002424201.1 218533386 7119317 163023..163418 1 NC_011758.1 PFAM: endoribonuclease L-PSP; KEGG: nfa:nfa26270 endoribonuclease; endoribonuclease L-PSP 163418 7119317 Mchl_5535 Methylobacterium extorquens CM4 endoribonuclease L-PSP YP_002424201.1 163023 D 440085 CDS YP_002424202.1 218533387 7119318 complement(163531..163794) 1 NC_011758.1 KEGG: syf:Synpcc7942_2103 hypothetical protein; hypothetical protein 163794 7119318 Mchl_5536 Methylobacterium extorquens CM4 hypothetical protein YP_002424202.1 163531 R 440085 CDS YP_002424203.1 218533388 7119320 164269..164559 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: mlo:msr5972 transposase; transposase IS3/IS911 family protein 164559 7119320 Mchl_5538 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424203.1 164269 D 440085 CDS YP_002424204.1 218533389 7119321 164556..165167 1 NC_011758.1 KEGG: mlo:mlr6150 transposase; transposase 165167 7119321 Mchl_5539 Methylobacterium extorquens CM4 transposase YP_002424204.1 164556 D 440085 CDS YP_002424205.1 218533390 7119322 165415..166494 1 NC_011758.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: ecp:ECP_4551 transposase; transposase IS116/IS110/IS902 family protein 166494 7119322 Mchl_5540 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002424205.1 165415 D 440085 CDS YP_002424206.1 218533391 7119324 complement(166792..167652) 1 NC_011758.1 PFAM: aminoglycoside phosphotransferase; KEGG: mex:Mext_1755 aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 167652 7119324 Mchl_5542 Methylobacterium extorquens CM4 aminoglycoside phosphotransferase YP_002424206.1 166792 R 440085 CDS YP_002424207.1 218533392 7119325 167882..168052 1 NC_011758.1 hypothetical protein 168052 7119325 Mchl_5543 Methylobacterium extorquens CM4 hypothetical protein YP_002424207.1 167882 D 440085 CDS YP_002424208.1 218533393 7119326 complement(168076..169326) 1 NC_011758.1 PFAM: glycosyl transferase family 28; KEGG: mpo:Mpop_2090 glycosyl transferase family 28; glycosyl transferase family 28 169326 7119326 Mchl_5544 Methylobacterium extorquens CM4 glycosyl transferase family 28 YP_002424208.1 168076 R 440085 CDS YP_002424209.1 218533394 7119327 complement(169323..170636) 1 NC_011758.1 KEGG: mpo:Mpop_2089 hypothetical protein; hypothetical protein 170636 7119327 Mchl_5545 Methylobacterium extorquens CM4 hypothetical protein YP_002424209.1 169323 R 440085 CDS YP_002424210.1 218533395 7119328 complement(170926..171351) 1 NC_011758.1 KEGG: mrd:Mrad2831_6474 hypothetical protein; hypothetical protein 171351 7119328 Mchl_5546 Methylobacterium extorquens CM4 hypothetical protein YP_002424210.1 170926 R 440085 CDS YP_002424211.1 218533396 7119329 171559..171771 1 NC_011758.1 KEGG: oan:Oant_4758 hypothetical protein; hypothetical protein 171771 7119329 Mchl_5547 Methylobacterium extorquens CM4 hypothetical protein YP_002424211.1 171559 D 440085 CDS YP_002424212.1 218533397 7119330 171787..172101 1 NC_011758.1 KEGG: mes:Meso_4589 hypothetical protein; hypothetical protein 172101 7119330 Mchl_5548 Methylobacterium extorquens CM4 hypothetical protein YP_002424212.1 171787 D 440085 CDS YP_002424213.1 218533398 7119331 172098..172484 1 NC_011758.1 KEGG: mes:Meso_3818 hypothetical protein; hypothetical protein 172484 7119331 Mchl_5549 Methylobacterium extorquens CM4 hypothetical protein YP_002424213.1 172098 D 440085 CDS YP_002424214.1 218533399 7119332 172551..172805 1 NC_011758.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: xau:Xaut_5007 prevent-host-death family protein; prevent-host-death family protein 172805 7119332 Mchl_5550 Methylobacterium extorquens CM4 prevent-host-death family protein YP_002424214.1 172551 D 440085 CDS YP_002424215.1 218533400 7119333 172789..173340 1 NC_011758.1 KEGG: rle:pRL100319 hypothetical protein; hypothetical protein 173340 7119333 Mchl_5551 Methylobacterium extorquens CM4 hypothetical protein YP_002424215.1 172789 D 440085 CDS YP_002424216.1 218533401 7119334 173413..173583 1 NC_011758.1 KEGG: sal:Sala_2631 hypothetical protein; hypothetical protein 173583 7119334 Mchl_5552 Methylobacterium extorquens CM4 hypothetical protein YP_002424216.1 173413 D 440085 CDS YP_002424217.1 218533402 7119335 173717..173959 1 NC_011758.1 KEGG: mpo:Mpop_1378 hypothetical protein; hypothetical protein 173959 7119335 Mchl_5553 Methylobacterium extorquens CM4 hypothetical protein YP_002424217.1 173717 D 440085 CDS YP_002424218.1 218533403 7119336 173963..174364 1 NC_011758.1 PFAM: PilT protein; KEGG: mpo:Mpop_1379 PilT protein; PilT protein 174364 7119336 Mchl_5554 Methylobacterium extorquens CM4 PilT protein YP_002424218.1 173963 D 440085 CDS YP_002424219.1 218533404 7119337 174776..175132 1 NC_011758.1 PFAM: protein of unknown function DUF736; KEGG: gdi:GDI2877 hypothetical protein; hypothetical protein 175132 7119337 Mchl_5555 Methylobacterium extorquens CM4 hypothetical protein YP_002424219.1 174776 D 440085 CDS YP_002424220.1 218533405 7119338 175476..177167 1 NC_011758.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: rru:Rru_A0755 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 177167 7119338 Mchl_5556 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002424220.1 175476 D 440085 CDS YP_002424221.1 218533406 7119339 complement(177559..178767) 1 NC_011758.1 PFAM: transposase mutator type; KEGG: mpo:Mpop_5445 transposase mutator type; transposase mutator type 178767 7119339 Mchl_5557 Methylobacterium extorquens CM4 transposase mutator type YP_002424221.1 177559 R 440085 CDS YP_002424222.1 218533407 7119340 178970..179986 1 NC_011758.1 PFAM: domain of unknown function DUF1738; KEGG: mrd:Mrad2831_6049 hypothetical protein; hypothetical protein 179986 7119340 Mchl_5558 Methylobacterium extorquens CM4 hypothetical protein YP_002424222.1 178970 D 440085 CDS YP_002424223.1 218533408 7119341 179986..180765 1 NC_011758.1 KEGG: mes:Meso_3816 hypothetical protein; hypothetical protein 180765 7119341 Mchl_5559 Methylobacterium extorquens CM4 hypothetical protein YP_002424223.1 179986 D 440085 CDS YP_002424224.1 218533409 7119342 complement(180777..181334) 1 NC_011758.1 hypothetical protein 181334 7119342 Mchl_5560 Methylobacterium extorquens CM4 hypothetical protein YP_002424224.1 180777 R 440085 CDS YP_002424225.1 218533410 7119343 complement(181433..181591) 1 NC_011758.1 hypothetical protein 181591 7119343 Mchl_5561 Methylobacterium extorquens CM4 hypothetical protein YP_002424225.1 181433 R 440085 CDS YP_002424226.1 218533411 7119344 complement(181658..181930) 1 NC_011758.1 hypothetical protein 181930 7119344 Mchl_5562 Methylobacterium extorquens CM4 hypothetical protein YP_002424226.1 181658 R 440085 CDS YP_002424227.1 218533412 7119345 182426..182890 1 NC_011758.1 hypothetical protein 182890 7119345 Mchl_5563 Methylobacterium extorquens CM4 hypothetical protein YP_002424227.1 182426 D 440085 CDS YP_002424228.1 218533413 7119346 183007..185286 1 NC_011758.1 SMART: ParB domain protein nuclease; KEGG: rpa:RPA2251 plasmid stabilization protein; ParB domain protein nuclease 185286 7119346 Mchl_5564 Methylobacterium extorquens CM4 ParB domain protein nuclease YP_002424228.1 183007 D 440085 CDS YP_002424229.1 218533414 7119347 185471..185785 1 NC_011758.1 KEGG: bbt:BBta_7412 hypothetical protein; hypothetical protein 185785 7119347 Mchl_5565 Methylobacterium extorquens CM4 hypothetical protein YP_002424229.1 185471 D 440085 CDS YP_002424230.1 218533415 7119348 complement(185797..186771) 1 NC_011758.1 PFAM: ROSMUCR transcriptional regulator; KEGG: mrd:Mrad2831_3868 MucR family transcriptional regulator; MucR family transcriptional regulator 186771 7119348 Mchl_5566 Methylobacterium extorquens CM4 MucR family transcriptional regulator YP_002424230.1 185797 R 440085 CDS YP_002424231.1 218533416 7119349 187004..191380 1 NC_011758.1 KEGG: mes:Meso_3828 probably methylase/helicase; probably methylase/helicase 191380 7119349 Mchl_5567 Methylobacterium extorquens CM4 probably methylase/helicase YP_002424231.1 187004 D 440085 CDS YP_002424232.1 218533417 7119350 191406..192464 1 NC_011758.1 KEGG: mrd:Mrad2831_6058 hypothetical protein; hypothetical protein 192464 7119350 Mchl_5568 Methylobacterium extorquens CM4 hypothetical protein YP_002424232.1 191406 D 440085 CDS YP_002424233.1 218533418 7119351 192799..193728 1 NC_011758.1 KEGG: mrd:Mrad2831_6059 hypothetical protein; hypothetical protein 193728 7119351 Mchl_5569 Methylobacterium extorquens CM4 hypothetical protein YP_002424233.1 192799 D 440085 CDS YP_002424234.1 218533419 7119352 complement(193725..194192) 1 NC_011758.1 hypothetical protein 194192 7119352 Mchl_5570 Methylobacterium extorquens CM4 hypothetical protein YP_002424234.1 193725 R 440085 CDS YP_002424235.1 218533420 7119353 195014..195187 1 NC_011758.1 KEGG: mrd:Mrad2831_6064 hypothetical protein; hypothetical protein 195187 7119353 Mchl_5571 Methylobacterium extorquens CM4 hypothetical protein YP_002424235.1 195014 D 440085 CDS YP_002424236.1 218533421 7119354 complement(195391..197415) 1 NC_011758.1 VirD4 family; conjugal transfer coupling protein TraG 197415 7119354 Mchl_5572 Methylobacterium extorquens CM4 conjugal transfer coupling protein TraG YP_002424236.1 195391 R 440085 CDS YP_002424237.1 218533422 7119355 complement(197412..197609) 1 NC_011758.1 PFAM: Conjugal transfer TraD family protein; KEGG: mrd:Mrad2831_6101 conjugal transfer protein TraD; conjugal transfer protein TraD 197609 7119355 Mchl_5573 Methylobacterium extorquens CM4 conjugal transfer protein TraD YP_002424237.1 197412 R 440085 CDS YP_002424238.1 218533423 7119356 complement(197593..197871) 1 NC_011758.1 KEGG: mrd:Mrad2831_6102 hypothetical protein; hypothetical protein 197871 7119356 Mchl_5574 Methylobacterium extorquens CM4 hypothetical protein YP_002424238.1 197593 R 440085 CDS YP_002424239.1 218533424 7119357 198365..202102 1 NC_011758.1 TIGRFAM: Ti-type conjugative transfer relaxase TraA; PFAM: MobA/MobL protein; KEGG: rle:pRL80122 conjugal transfer protein TraA; Ti-type conjugative transfer relaxase TraA 202102 7119357 Mchl_5575 Methylobacterium extorquens CM4 Ti-type conjugative transfer relaxase TraA YP_002424239.1 198365 D 440085 CDS YP_002424240.1 218533425 7119112 202258..202608 1 NC_011758.1 KEGG: gox:GOX2661 hypothetical protein; hypothetical protein 202608 7119112 Mchl_5576 Methylobacterium extorquens CM4 hypothetical protein YP_002424240.1 202258 D 440085 CDS YP_002424241.1 218533426 7119113 202605..203222 1 NC_011758.1 hypothetical protein 203222 7119113 Mchl_5577 Methylobacterium extorquens CM4 hypothetical protein YP_002424241.1 202605 D 440085 CDS YP_002424242.1 218533427 7119114 203451..203738 1 NC_011758.1 hypothetical protein 203738 7119114 Mchl_5578 Methylobacterium extorquens CM4 hypothetical protein YP_002424242.1 203451 D 440085 CDS YP_002424243.1 218533428 7119115 203735..205033 1 NC_011758.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: dsy:DSY2769 hypothetical protein; filamentation induced by cAMP protein Fic 205033 7119115 Mchl_5579 Methylobacterium extorquens CM4 filamentation induced by cAMP protein Fic YP_002424243.1 203735 D 440085 CDS YP_002424244.1 218533429 7119116 205030..205944 1 NC_011758.1 KEGG: pau:PA14_12280 apolipoprotein N-acyltransferase; hypothetical protein 205944 7119116 Mchl_5580 Methylobacterium extorquens CM4 hypothetical protein YP_002424244.1 205030 D 440085 CDS YP_002424245.1 218533430 7119117 complement(join(206019..206492,206492..206824)) 1 NC_011758.1 KEGG: mrd:Mrad2831_6465 hypothetical protein; hypothetical protein 206824 7119117 Mchl_5581 Methylobacterium extorquens CM4 hypothetical protein YP_002424245.1 206019 R 440085 CDS YP_002424246.1 218533431 7119118 complement(207108..208283) 1 NC_011758.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: rpa:RPA2080 zinc-containing dehydrogenase; alcohol dehydrogenase GroES 208283 7119118 Mchl_5582 Methylobacterium extorquens CM4 alcohol dehydrogenase GroES YP_002424246.1 207108 R 440085 CDS YP_002424247.1 218533432 7119121 210800..211429 1 NC_011758.1 PFAM: phosphoglycerate mutase; KEGG: swi:Swit_5116 phosphoglycerate mutase; phosphoglycerate mutase 211429 7119121 Mchl_5585 Methylobacterium extorquens CM4 phosphoglycerate mutase YP_002424247.1 210800 D 440085 CDS YP_002424248.1 218533433 7119123 213468..214121 1 NC_011758.1 KEGG: met:M446_6984 hypothetical protein; hypothetical protein 214121 7119123 Mchl_5587 Methylobacterium extorquens CM4 hypothetical protein YP_002424248.1 213468 D 440085 CDS YP_002424249.1 218533434 7119124 214121..214453 1 NC_011758.1 hypothetical protein 214453 7119124 Mchl_5588 Methylobacterium extorquens CM4 hypothetical protein YP_002424249.1 214121 D 440085 CDS YP_002424250.1 218533435 7119126 complement(join(214586..215059,215059..215391)) 1 NC_011758.1 KEGG: mrd:Mrad2831_6465 hypothetical protein; hypothetical protein 215391 7119126 Mchl_5590 Methylobacterium extorquens CM4 hypothetical protein YP_002424250.1 214586 R 440085 CDS YP_002424251.1 218533436 7119127 complement(215441..215857) 1 NC_011758.1 KEGG: bvi:Bcep1808_7364 hypothetical protein; hypothetical protein 215857 7119127 Mchl_5591 Methylobacterium extorquens CM4 hypothetical protein YP_002424251.1 215441 R 440085 CDS YP_002424252.1 218533437 7119128 complement(215854..218841) 1 NC_011758.1 KEGG: lpf:lpl0498 hypothetical protein; hypothetical protein 218841 7119128 Mchl_5592 Methylobacterium extorquens CM4 hypothetical protein YP_002424252.1 215854 R 440085 CDS YP_002424253.1 218533438 7119129 complement(218838..219308) 1 NC_011758.1 hypothetical protein 219308 7119129 Mchl_5593 Methylobacterium extorquens CM4 hypothetical protein YP_002424253.1 218838 R 440085 CDS YP_002424254.1 218533439 7119130 complement(219320..219574) 1 NC_011758.1 hypothetical protein 219574 7119130 Mchl_5594 Methylobacterium extorquens CM4 hypothetical protein YP_002424254.1 219320 R 440085 CDS YP_002424255.1 218533440 7119131 complement(219571..220854) 1 NC_011758.1 KEGG: lpc:LPC_2892 IcmE (DotG); hypothetical protein 220854 7119131 Mchl_5595 Methylobacterium extorquens CM4 hypothetical protein YP_002424255.1 219571 R 440085 CDS YP_002424256.1 218533441 7119132 complement(220866..222053) 1 NC_011758.1 KEGG: bvi:Bcep1808_7368 IcmK-like type IV secretion system protein; hypothetical protein 222053 7119132 Mchl_5596 Methylobacterium extorquens CM4 hypothetical protein YP_002424256.1 220866 R 440085 CDS YP_002424257.1 218533442 7119133 complement(222050..222706) 1 NC_011758.1 KEGG: bvi:Bcep1808_7369 hypothetical protein; hypothetical protein 222706 7119133 Mchl_5597 Methylobacterium extorquens CM4 hypothetical protein YP_002424257.1 222050 R 440085 CDS YP_002424258.1 218533443 7119134 complement(222703..222978) 1 NC_011758.1 hypothetical protein 222978 7119134 Mchl_5598 Methylobacterium extorquens CM4 hypothetical protein YP_002424258.1 222703 R 440085 CDS YP_002424259.1 218533444 7119135 complement(222980..223756) 1 NC_011758.1 KEGG: acb:A1S_0640 hypothetical protein; hypothetical protein 223756 7119135 Mchl_5599 Methylobacterium extorquens CM4 hypothetical protein YP_002424259.1 222980 R 440085 CDS YP_002424260.1 218533445 7119136 224338..224904 1 NC_011758.1 KEGG: ypi:YpsIP31758_B0118 type IV secretion system protein IcmC/DotIE; hypothetical protein 224904 7119136 Mchl_5600 Methylobacterium extorquens CM4 hypothetical protein YP_002424260.1 224338 D 440085 CDS YP_002424261.1 218533446 7119137 complement(224921..225442) 1 NC_011758.1 hypothetical protein 225442 7119137 Mchl_5601 Methylobacterium extorquens CM4 hypothetical protein YP_002424261.1 224921 R 440085 CDS YP_002424262.1 218533447 7119138 225686..226840 1 NC_011758.1 KEGG: bvi:Bcep1808_7385 DotC protein; hypothetical protein 226840 7119138 Mchl_5602 Methylobacterium extorquens CM4 hypothetical protein YP_002424262.1 225686 D 440085 CDS YP_002424263.1 218533448 7119139 226844..228025 1 NC_011758.1 PFAM: type II secretion system protein E; KEGG: cbd:CBUD_0350 Dot/Icm secretion system ATPase DotB; type II secretion system protein E 228025 7119139 Mchl_5603 Methylobacterium extorquens CM4 type II secretion system protein E YP_002424263.1 226844 D 440085 CDS YP_002424264.1 218533449 7119140 228006..228644 1 NC_011758.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: bvi:Bcep1808_7376 hypothetical protein; hypothetical protein 228644 7119140 Mchl_5604 Methylobacterium extorquens CM4 hypothetical protein YP_002424264.1 228006 D 440085 CDS YP_002424265.1 218533450 7119141 228641..228886 1 NC_011758.1 hypothetical protein 228886 7119141 Mchl_5605 Methylobacterium extorquens CM4 hypothetical protein YP_002424265.1 228641 D 440085 CDS YP_002424266.1 218533451 7119142 228871..229548 1 NC_011758.1 KEGG: bvi:Bcep1808_7328 hypothetical protein; hypothetical protein 229548 7119142 Mchl_5606 Methylobacterium extorquens CM4 hypothetical protein YP_002424266.1 228871 D 440085 CDS YP_002424267.1 218533452 7119143 229545..229943 1 NC_011758.1 hypothetical protein 229943 7119143 Mchl_5607 Methylobacterium extorquens CM4 hypothetical protein YP_002424267.1 229545 D 440085 CDS YP_002424268.1 218533453 7119144 229940..230890 1 NC_011758.1 PFAM: peptidase M23; KEGG: pvi:Cvib_1676 peptidase M23B; peptidase M23 230890 7119144 Mchl_5608 Methylobacterium extorquens CM4 peptidase M23 YP_002424268.1 229940 D 440085 CDS YP_002424269.1 218533454 7119145 230887..231651 1 NC_011758.1 KEGG: bvi:Bcep1808_7327 hypothetical protein; hypothetical protein 231651 7119145 Mchl_5609 Methylobacterium extorquens CM4 hypothetical protein YP_002424269.1 230887 D 440085 CDS YP_002424270.1 218533455 7119146 231648..232670 1 NC_011758.1 KEGG: bvi:Bcep1808_7326 hypothetical protein; hypothetical protein 232670 7119146 Mchl_5610 Methylobacterium extorquens CM4 hypothetical protein YP_002424270.1 231648 D 440085 CDS YP_002424271.1 218533456 7119147 232667..233653 1 NC_011758.1 KEGG: bvi:Bcep1808_7325 hypothetical protein; hypothetical protein 233653 7119147 Mchl_5611 Methylobacterium extorquens CM4 hypothetical protein YP_002424271.1 232667 D 440085 CDS YP_002424272.1 218533457 7119148 233662..235920 1 NC_011758.1 KEGG: rme:Rmet_2827 TraY/DotA-like type IV secretion system protein; hypothetical protein 235920 7119148 Mchl_5612 Methylobacterium extorquens CM4 hypothetical protein YP_002424272.1 233662 D 440085 CDS YP_002424273.1 218533458 7119149 235924..237246 1 NC_011758.1 hypothetical protein 237246 7119149 Mchl_5613 Methylobacterium extorquens CM4 hypothetical protein YP_002424273.1 235924 D 440085 CDS YP_002424274.1 218533459 7119150 237350..237976 1 NC_011758.1 KEGG: bja:bll8291 transposase; transposase 237976 7119150 Mchl_5614 Methylobacterium extorquens CM4 transposase YP_002424274.1 237350 D 440085 CDS YP_002424275.1 218533460 7119151 237990..239216 1 NC_011758.1 TIGRFAM: plasmid partitioning protein RepA; PFAM: regulatory protein MerR; cobyrinic acid ac-diamide synthase; KEGG: mrd:Mrad2831_5912 plasmid partitioning protein RepA; plasmid partitioning protein RepA 239216 7119151 Mchl_5615 Methylobacterium extorquens CM4 plasmid partitioning protein RepA YP_002424275.1 237990 D 440085 CDS YP_002424276.1 218533461 7119152 239213..240217 1 NC_011758.1 TIGRFAM: parB-like partition protein; plasmid partitioning protein RepB; PFAM: ParB domain protein nuclease; RepB plasmid partition; KEGG: mrd:Mrad2831_5913 plasmid partitioning protein RepB; plasmid partitioning protein RepB 240217 7119152 Mchl_5616 Methylobacterium extorquens CM4 plasmid partitioning protein RepB YP_002424276.1 239213 D 440085 CDS YP_002424277.1 218533462 7119153 240422..241633 1 NC_011758.1 PFAM: replication protein C; KEGG: mes:Meso_4192 replication protein C; replication initiation protein RepC 241633 7119153 Mchl_5617 Methylobacterium extorquens CM4 replication initiation protein RepC YP_002424277.1 240422 D 440085 CDS YP_002424278.1 218533463 7119158 join(243536..244027,244027..244596) 1 NC_011758.1 KEGG: rle:pRL70033 hypothetical protein; transposase 244596 7119158 Mchl_5622 Methylobacterium extorquens CM4 transposase YP_002424278.1 243536 D 440085 CDS YP_002424279.1 218533464 7119160 245135..246649 1 NC_011758.1 PFAM: integrase; KEGG: bja:bll5000 transposase; integrase 246649 7119160 Mchl_5624 Methylobacterium extorquens CM4 integrase YP_002424279.1 245135 D 440085 CDS YP_002424280.1 218533465 7119161 246646..247470 1 NC_011758.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: bja:bll4999 transposase; transposase 247470 7119161 Mchl_5625 Methylobacterium extorquens CM4 transposase YP_002424280.1 246646 D 440085 CDS YP_002424281.1 218533466 7119162 247666..248919 1 NC_011758.1 KEGG: met:M446_6861 transposase; transposase 248919 7119162 Mchl_5626 Methylobacterium extorquens CM4 transposase YP_002424281.1 247666 D 440085 CDS YP_002424282.1 218533467 7119163 join(249082..249399,249399..249848) 1 NC_011758.1 KEGG: mex:Mext_0768 transposase; hypothetical protein 249848 7119163 Mchl_5627 Methylobacterium extorquens CM4 hypothetical protein YP_002424282.1 249082 D 440085 CDS YP_002424283.1 218533468 7119164 249897..250493 1 NC_011758.1 PFAM: resolvase; Resolvase helix-turn-helix domain protein; KEGG: mrd:Mrad2831_6417 resolvase domain-containing protein; resolvase 250493 7119164 Mchl_5628 Methylobacterium extorquens CM4 resolvase YP_002424283.1 249897 D 440085 CDS YP_002424284.1 218533469 7119165 250577..250867 1 NC_011758.1 PFAM: protein of unknown function DUF497; KEGG: cyt:cce_4967 hypothetical protein; hypothetical protein 250867 7119165 Mchl_5629 Methylobacterium extorquens CM4 hypothetical protein YP_002424284.1 250577 D 440085 CDS YP_002424285.1 218533470 7119166 250851..251105 1 NC_011758.1 KEGG: ccr:CC_0488 hypothetical protein; hypothetical protein 251105 7119166 Mchl_5630 Methylobacterium extorquens CM4 hypothetical protein YP_002424285.1 250851 D 440085 CDS YP_002424286.1 218533471 7119168 join(252845..253177,253177..253650) 1 NC_011758.1 KEGG: scl:sce5216 transposase, probable; hypothetical protein 253650 7119168 Mchl_5632 Methylobacterium extorquens CM4 hypothetical protein YP_002424286.1 252845 D 440085 CDS YP_002424287.1 218533472 7119169 complement(253765..254808) 1 NC_011758.1 KEGG: mst:Msp_0767 helicase; hypothetical protein 254808 7119169 Mchl_5633 Methylobacterium extorquens CM4 hypothetical protein YP_002424287.1 253765 R 440085 CDS YP_002424288.1 218533473 7119170 complement(254817..257630) 1 NC_011758.1 KEGG: pla:Plav_2607 methylase; methylase 257630 7119170 Mchl_5634 Methylobacterium extorquens CM4 methylase YP_002424288.1 254817 R 440085 CDS YP_002424289.1 218533474 7119171 complement(257810..258550) 1 NC_011758.1 hypothetical protein 258550 7119171 Mchl_5635 Methylobacterium extorquens CM4 hypothetical protein YP_002424289.1 257810 R 440085 CDS YP_002424290.1 218533475 7119172 complement(join(258609..259040,259040..259366)) 1 NC_011758.1 KEGG: mpo:Mpop_3783 hypothetical protein; hypothetical protein 259366 7119172 Mchl_5636 Methylobacterium extorquens CM4 hypothetical protein YP_002424290.1 258609 R 440085 CDS YP_002424291.1 218533476 7119175 259870..261075 1 NC_011758.1 PFAM: major royal jelly protein; KEGG: mrd:Mrad2831_5890 hypothetical protein; major royal jelly protein 261075 7119175 Mchl_5639 Methylobacterium extorquens CM4 major royal jelly protein YP_002424291.1 259870 D 440085 CDS YP_002424292.1 218533477 7119177 261916..263193 1 NC_011758.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: oan:Oant_4628 transposase IS116/IS110/IS902 family protein; transposase IS116/IS110/IS902 family protein 263193 7119177 Mchl_5641 Methylobacterium extorquens CM4 transposase IS116/IS110/IS902 family protein YP_002424292.1 261916 D 440085 CDS YP_002424293.1 218533478 7119178 263326..263610 1 NC_011758.1 PFAM: transposase IS3/IS911 family protein; KEGG: sal:Sala_0416 transposase IS3/IS911; transposase IS3/IS911 family protein 263610 7119178 Mchl_5642 Methylobacterium extorquens CM4 transposase IS3/IS911 family protein YP_002424293.1 263326 D 440085 CDS YP_002424294.1 218533479 7119179 263607..264497 1 NC_011758.1 PFAM: integrase; KEGG: gdi:GDI0980 integrase; integrase 264497 7119179 Mchl_5643 Methylobacterium extorquens CM4 integrase YP_002424294.1 263607 D 440085 CDS YP_002424295.1 218533480 7119180 complement(264707..265096) 1 NC_011758.1 PFAM: PilT protein; KEGG: ccr:CC_0841 hypothetical protein; PilT protein 265096 7119180 Mchl_5644 Methylobacterium extorquens CM4 PilT protein YP_002424295.1 264707 R 440085 CDS YP_002424296.1 218533481 7119181 complement(265089..265388) 1 NC_011758.1 TIGRFAM: AbrB family transcriptional regulator; KEGG: gox:GOX2681 hypothetical protein; AbrB family transcriptional regulator 265388 7119181 Mchl_5645 Methylobacterium extorquens CM4 AbrB family transcriptional regulator YP_002424296.1 265089 R 440085 CDS YP_002424297.1 218533482 7119182 265577..266638 1 NC_011758.1 PFAM: integrase; KEGG: mrd:Mrad2831_6128 integrase; integrase 266638 7119182 Mchl_5646 Methylobacterium extorquens CM4 integrase YP_002424297.1 265577 D 440085 CDS YP_002424298.1 218533483 7119183 complement(267083..268171) 1 NC_011758.1 TIGRFAM: addiction module antidote protein, HigA family; SMART: helix-turn-helix domain protein; KEGG: rru:Rru_A0006 plasmid maintenance system antidote protein; XRE family transcripitonal regulator 268171 7119183 Mchl_5647 Methylobacterium extorquens CM4 XRE family transcripitonal regulator YP_002424298.1 267083 R 440085 CDS YP_002424299.1 218533484 7119184 268467..270011 1 NC_011758.1 KEGG: ccr:CC_2700 hypothetical protein; hypothetical protein 270011 7119184 Mchl_5648 Methylobacterium extorquens CM4 hypothetical protein YP_002424299.1 268467 D 440085 CDS YP_002424300.1 218533485 7119185 270015..270800 1 NC_011758.1 KEGG: ccr:CC_2701 hypothetical protein; hypothetical protein 270800 7119185 Mchl_5649 Methylobacterium extorquens CM4 hypothetical protein YP_002424300.1 270015 D 440085 CDS YP_002424301.1 218533486 7119186 270811..271713 1 NC_011758.1 PFAM: cyclic nucleotide-binding; KEGG: mrd:Mrad2831_6138 cyclic nucleotide-binding; cyclic nucleotide-binding 271713 7119186 Mchl_5650 Methylobacterium extorquens CM4 cyclic nucleotide-binding YP_002424301.1 270811 D 440085 CDS YP_002424302.1 218533487 7119187 272002..273888 1 NC_011758.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: rpc:RPC_1792 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 273888 7119187 Mchl_5651 Methylobacterium extorquens CM4 peptidase S8/S53 subtilisin kexin sedolisin YP_002424302.1 272002 D 440085 CDS YP_002424303.1 218533488 7119188 273901..275142 1 NC_011758.1 KEGG: rpc:RPC_1793 hypothetical protein; hypothetical protein 275142 7119188 Mchl_5652 Methylobacterium extorquens CM4 hypothetical protein YP_002424303.1 273901 D 440085 CDS YP_002424304.1 218533489 7119189 276005..277591 1 NC_011758.1 KEGG: rpb:RPB_3790 hypothetical protein; hypothetical protein 277591 7119189 Mchl_5653 Methylobacterium extorquens CM4 hypothetical protein YP_002424304.1 276005 D 440085 CDS YP_002424305.1 218533490 7119190 277666..279204 1 NC_011758.1 PFAM: integrase; KEGG: acr:Acry_3593 integrase catalytic subunit; integrase 279204 7119190 Mchl_5654 Methylobacterium extorquens CM4 integrase YP_002424305.1 277666 D 440085 CDS YP_002424306.1 218533491 7119191 279216..279959 1 NC_011758.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding domain protein; KEGG: nha:Nham_2786 IstB-like ATP-binding protein; IstB domain protein ATP-binding protein 279959 7119191 Mchl_5655 Methylobacterium extorquens CM4 IstB domain protein ATP-binding protein YP_002424306.1 279216 D 440085 CDS YP_002424307.1 218533492 7119192 280709..282358 1 NC_011758.1 KEGG: gur:Gura_2918 hypothetical protein; hypothetical protein 282358 7119192 Mchl_5656 Methylobacterium extorquens CM4 hypothetical protein YP_002424307.1 280709 D 440085 CDS YP_002424308.1 218533493 7119193 282361..284340 1 NC_011758.1 hypothetical protein 284340 7119193 Mchl_5657 Methylobacterium extorquens CM4 hypothetical protein YP_002424308.1 282361 D 440085 CDS YP_002424309.1 218533494 7119007 284496..285119 1 NC_011758.1 hypothetical protein 285119 7119007 Mchl_5658 Methylobacterium extorquens CM4 hypothetical protein YP_002424309.1 284496 D 440085 CDS YP_002424310.1 218533495 7119008 complement(285217..289176) 1 NC_011758.1 KEGG: eca:ECA0413 hypothetical protein; hypothetical protein 289176 7119008 Mchl_5659 Methylobacterium extorquens CM4 hypothetical protein YP_002424310.1 285217 R 440085 CDS YP_002424311.1 218533496 7119009 289206..290303 1 NC_011758.1 PFAM: transposase IS4 family protein; KEGG: nha:Nham_1266 transposase, IS4; transposase IS4 family protein 290303 7119009 Mchl_5660 Methylobacterium extorquens CM4 transposase IS4 family protein YP_002424311.1 289206 D 440085 CDS YP_002424312.1 218533497 7119010 290300..290626 1 NC_011758.1 KEGG: met:M446_2802 hypothetical protein; hypothetical protein 290626 7119010 Mchl_5661 Methylobacterium extorquens CM4 hypothetical protein YP_002424312.1 290300 D 440085 CDS YP_002424313.1 218533498 7119011 290920..292248 1 NC_011758.1 KEGG: met:M446_6572 hypothetical protein; hypothetical protein 292248 7119011 Mchl_5662 Methylobacterium extorquens CM4 hypothetical protein YP_002424313.1 290920 D 440085 CDS YP_002424314.1 218533499 7119012 complement(292469..293899) 1 NC_011758.1 KEGG: xau:Xaut_1068 hypothetical protein; hypothetical protein 293899 7119012 Mchl_5663 Methylobacterium extorquens CM4 hypothetical protein YP_002424314.1 292469 R 440085 CDS YP_002424315.1 218533500 7119013 complement(293913..297461) 1 NC_011758.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: pen:PSEEN4433 subtilisin-like serine protease; peptidase S8/S53 subtilisin kexin sedolisin 297461 7119013 Mchl_5664 Methylobacterium extorquens CM4 peptidase S8/S53 subtilisin kexin sedolisin YP_002424315.1 293913 R 440085 CDS YP_002424316.1 218533501 7119015 complement(297893..299113) 1 NC_011758.1 KEGG: bbt:BBta_7549 hypothetical protein; hypothetical protein 299113 7119015 Mchl_5666 Methylobacterium extorquens CM4 hypothetical protein YP_002424316.1 297893 R 440085 CDS YP_002424317.1 218533502 7119016 complement(299590..300135) 1 NC_011758.1 PFAM: metallophosphoesterase; KEGG: mex:Mext_1922 metallophosphoesterase; metallophosphoesterase 300135 7119016 Mchl_5667 Methylobacterium extorquens CM4 metallophosphoesterase YP_002424317.1 299590 R 440085 CDS YP_002424318.1 218533503 7119017 complement(300224..301273) 1 NC_011758.1 KEGG: mpo:Mpop_2589 hypothetical protein; hypothetical protein 301273 7119017 Mchl_5668 Methylobacterium extorquens CM4 hypothetical protein YP_002424318.1 300224 R 440085 CDS YP_002424319.1 218533504 7119018 complement(301288..303387) 1 NC_011758.1 PFAM: peptidase M41; ATPase AAA central domain protein; SMART: ATPase AAA; KEGG: mrd:Mrad2831_4675 ATPase central domain-containing protein; ATPase AAA 303387 7119018 Mchl_5669 Methylobacterium extorquens CM4 ATPase AAA YP_002424319.1 301288 R 440085 CDS YP_002424320.1 218533505 7119019 complement(303448..304467) 1 NC_011758.1 KEGG: mpo:Mpop_4063 metallophosphoesterase; metallophosphoesterase 304467 7119019 Mchl_5670 Methylobacterium extorquens CM4 metallophosphoesterase YP_002424320.1 303448 R 440085 CDS YP_002424321.1 218533506 7119020 complement(304546..305034) 1 NC_011758.1 KEGG: mpo:Mpop_2594 hypothetical protein; hypothetical protein 305034 7119020 Mchl_5671 Methylobacterium extorquens CM4 hypothetical protein YP_002424321.1 304546 R 440085 CDS YP_002424322.1 218533507 7119021 complement(305165..306178) 1 NC_011758.1 KEGG: mpo:Mpop_2595 hypothetical protein; hypothetical protein 306178 7119021 Mchl_5672 Methylobacterium extorquens CM4 hypothetical protein YP_002424322.1 305165 R 440085 CDS YP_002424323.1 218533508 7119023 complement(306752..309673) 1 NC_011758.1 SMART: hypothetical protein; KEGG: sco:SCO5953 hypothetical protein; hypothetical protein 309673 7119023 Mchl_5674 Methylobacterium extorquens CM4 hypothetical protein YP_002424323.1 306752 R 440085 CDS YP_002424324.1 218533509 7119024 complement(309770..312754) 1 NC_011758.1 SMART: hypothetical protein; pyrrolo-quinoline quinone; KEGG: mmi:MMAR_3405 regulatory protein; pyrrolo-quinoline quinone 312754 7119024 Mchl_5675 Methylobacterium extorquens CM4 pyrrolo-quinoline quinone YP_002424324.1 309770 R 440085 CDS YP_002424325.1 218533510 7119025 313514..315502 1 NC_011758.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mpo:Mpop_3807 TonB-dependent receptor plug; TonB-dependent receptor plug 315502 7119025 Mchl_5676 Methylobacterium extorquens CM4 TonB-dependent receptor plug YP_002424325.1 313514 D 440085 CDS YP_002424326.1 218533511 7119026 315513..316385 1 NC_011758.1 PFAM: periplasmic binding protein; KEGG: mpo:Mpop_3806 periplasmic binding protein; periplasmic binding protein 316385 7119026 Mchl_5677 Methylobacterium extorquens CM4 periplasmic binding protein YP_002424326.1 315513 D 440085 CDS YP_002424327.1 218533512 7119027 316382..317410 1 NC_011758.1 PFAM: transporter permease; KEGG: mex:Mext_2927 transporter permease; transporter permease 317410 7119027 Mchl_5678 Methylobacterium extorquens CM4 transporter permease YP_002424327.1 316382 D 440085 CDS YP_002424328.1 218533513 7119028 317407..318219 1 NC_011758.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: mrd:Mrad2831_6080 ABC transporter; ABC transporter 318219 7119028 Mchl_5679 Methylobacterium extorquens CM4 ABC transporter YP_002424328.1 317407 D 440085 CDS YP_002424329.1 218533514 7119029 318206..319174 1 NC_011758.1 KEGG: mpo:Mpop_3803 hypothetical protein; hypothetical protein 319174 7119029 Mchl_5680 Methylobacterium extorquens CM4 hypothetical protein YP_002424329.1 318206 D 440085 CDS YP_002424330.1 218533515 7119030 319171..319695 1 NC_011758.1 KEGG: mpo:Mpop_3802 hypothetical protein; hypothetical protein 319695 7119030 Mchl_5681 Methylobacterium extorquens CM4 hypothetical protein YP_002424330.1 319171 D 440085 CDS YP_002424331.1 218533516 7119031 319845..321863 1 NC_011758.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mrd:Mrad2831_4063 TonB-dependent receptor plug; TonB-dependent receptor plug 321863 7119031 Mchl_5682 Methylobacterium extorquens CM4 TonB-dependent receptor plug YP_002424331.1 319845 D 440085 CDS YP_002424332.1 218533517 7119032 323442..324728 1 NC_011758.1 PFAM: MOFRL domain protein; KEGG: mex:Mext_2747 hydroxypyruvate reductase; hydroxypyruvate reductase 324728 7119032 Mchl_5683 Methylobacterium extorquens CM4 hydroxypyruvate reductase YP_002424332.1 323442 D 440085 CDS YP_002424333.1 218533518 7119034 complement(325222..326004) 1 NC_011758.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mpo:Mpop_0969 precorrin-4 C11-methyltransferase; precorrin-4 C11-methyltransferase 326004 7119034 Mchl_5685 Methylobacterium extorquens CM4 precorrin-4 C11-methyltransferase YP_002424333.1 325222 R 440085 CDS YP_002424334.1 218533519 7119035 complement(326001..326369) 1 NC_011758.1 KEGG: mex:Mext_1035 CobE protein; CobE protein 326369 7119035 Mchl_5686 Methylobacterium extorquens CM4 CobE protein YP_002424334.1 326001 R 440085 CDS YP_002424335.1 218533520 7119036 complement(326366..327607) 1 NC_011758.1 KEGG: mrd:Mrad2831_3121 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 327607 7119036 Mchl_5687 Methylobacterium extorquens CM4 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_002424335.1 326366 R 440085 CDS YP_002424336.1 218533521 7119037 327636..328388 1 NC_011758.1 KEGG: mrd:Mrad2831_3120 precorrin-6A reductase; TIGRFAM: precorrin-6x reductase; PFAM: precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 328388 7119037 Mchl_5688 Methylobacterium extorquens CM4 precorrin-6x reductase YP_002424336.1 327636 D 440085 CDS YP_002424337.1 218533522 7119038 complement(328427..329197) 1 NC_011758.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2442 precorrin-3B C17-methyltransferase; precorrin-3B C17-methyltransferase 329197 7119038 Mchl_5689 Methylobacterium extorquens CM4 precorrin-3B C17-methyltransferase YP_002424337.1 328427 R 440085 CDS YP_002424338.1 218533523 7119039 complement(329194..329961) 1 NC_011758.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mpo:Mpop_1433 precorrin-2 C20-methyltransferase; precorrin-2 C20-methyltransferase 329961 7119039 Mchl_5690 Methylobacterium extorquens CM4 precorrin-2 C20-methyltransferase YP_002424338.1 329194 R 440085 CDS YP_002424339.1 218533524 7119040 complement(329961..330593) 1 NC_011758.1 PFAM: precorrin-8X methylmutase CbiC/CobH; KEGG: mpo:Mpop_1434 precorrin-8X methylmutase; precorrin-8X methylmutase 330593 7119040 Mchl_5691 Methylobacterium extorquens CM4 precorrin-8X methylmutase YP_002424339.1 329961 R 440085 CDS YP_002424340.1 218533525 7119041 complement(330676..331311) 1 NC_011758.1 KEGG: mrd:Mrad2831_3114 cobalamin biosynthesis protein CobW; hypothetical protein 331311 7119041 Mchl_5692 Methylobacterium extorquens CM4 hypothetical protein YP_002424340.1 330676 R 440085 CDS YP_002424341.1 218533526 7119042 complement(331665..332594) 1 NC_011758.1 KEGG: mrd:Mrad2831_1569 hypothetical protein; hypothetical protein 332594 7119042 Mchl_5693 Methylobacterium extorquens CM4 hypothetical protein YP_002424341.1 331665 R 440085 CDS YP_002424342.1 218533527 7119043 complement(333494..334726) 1 NC_011758.1 KEGG: reu:Reut_A2713 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; amidohydrolase; imidazolonepropionase 334726 7119043 Mchl_5694 Methylobacterium extorquens CM4 imidazolonepropionase YP_002424342.1 333494 R 440085 CDS YP_002424343.1 218533528 7119046 complement(335161..337014) 1 NC_011758.1 TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: uroporphyrinogen decarboxylase (URO-D); methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: mta:Moth_1447 cobalamin B12-binding; methyltransferase MtaA/CmuA family 337014 7119046 Mchl_5697 Methylobacterium extorquens CM4 methyltransferase MtaA/CmuA family YP_002424343.1 335161 R 440085 CDS YP_002424344.1 218533529 7119047 complement(337039..338136) 1 NC_011758.1 hypothetical protein 338136 7119047 Mchl_5698 Methylobacterium extorquens CM4 hypothetical protein YP_002424344.1 337039 R 440085 CDS YP_002424345.1 218533530 7119048 339062..339925 1 NC_011758.1 TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein; KEGG: azc:AZC_1492 formyltetrahydrofolate deformylase; formyltetrahydrofolate deformylase 339925 7119048 Mchl_5699 Methylobacterium extorquens CM4 formyltetrahydrofolate deformylase YP_002424345.1 339062 D 440085 CDS YP_002424346.1 218533531 7119049 340046..340966 1 NC_011758.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: pde:Pden_2614 methenyltetrahydrofolate cyclohydrolase; methenyltetrahydrofolate cyclohydrolase 340966 7119049 Mchl_5700 Methylobacterium extorquens CM4 methenyltetrahydrofolate cyclohydrolase YP_002424346.1 340046 D 440085 CDS YP_002424347.1 218533532 7119050 340969..342372 1 NC_011758.1 KEGG: met:M446_0475 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; FolC bifunctional protein 342372 7119050 Mchl_5701 Methylobacterium extorquens CM4 FolC bifunctional protein YP_002424347.1 340969 D 440085 CDS YP_002424348.1 218533533 7119051 342409..343437 1 NC_011758.1 KEGG: ret:RHE_CH02443 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase 343437 7119051 Mchl_5702 Methylobacterium extorquens CM4 nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase YP_002424348.1 342409 D 440085 CDS YP_002424349.1 218533534 7119055 complement(345064..345654) 1 NC_011758.1 KEGG: mpo:Mpop_4062 hypothetical protein; hypothetical protein 345654 7119055 Mchl_5706 Methylobacterium extorquens CM4 hypothetical protein YP_002424349.1 345064 R 440085 CDS YP_002424350.1 218533535 7119056 complement(345916..346932) 1 NC_011758.1 KEGG: mpo:Mpop_4063 metallophosphoesterase; metallophosphoesterase 346932 7119056 Mchl_5707 Methylobacterium extorquens CM4 metallophosphoesterase YP_002424350.1 345916 R 440085 CDS YP_002424351.1 218533536 7119057 complement(347120..348394) 1 NC_011758.1 PFAM: metallophosphoesterase; KEGG: mpo:Mpop_4064 metallophosphoesterase; metallophosphoesterase 348394 7119057 Mchl_5708 Methylobacterium extorquens CM4 metallophosphoesterase YP_002424351.1 347120 R 440085 CDS YP_002424352.1 218533537 7119058 complement(348527..349504) 1 NC_011758.1 KEGG: mpo:Mpop_4065 hypothetical protein; hypothetical protein 349504 7119058 Mchl_5709 Methylobacterium extorquens CM4 hypothetical protein YP_002424352.1 348527 R 440085 CDS YP_002424353.1 218533538 7119059 349689..350048 1 NC_011758.1 KEGG: mpo:Mpop_2596 transcriptional regulator, XRE family; XRE family transcriptional regulator 350048 7119059 Mchl_5710 Methylobacterium extorquens CM4 XRE family transcriptional regulator YP_002424353.1 349689 D 440085 CDS YP_002424354.1 218533539 7119061 complement(350477..351928) 1 NC_011758.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mrd:Mrad2831_1242 integral membrane sensor signal transduction histidine kinase; histidine kinase 351928 7119061 Mchl_5712 Methylobacterium extorquens CM4 histidine kinase YP_002424354.1 350477 R 440085 CDS YP_002424355.1 218533540 7119062 complement(351921..352598) 1 NC_011758.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mrd:Mrad2831_1241 two component transcriptional regulator; transcriptional regulator 352598 7119062 Mchl_5713 Methylobacterium extorquens CM4 transcriptional regulator YP_002424355.1 351921 R 440085 CDS YP_002424356.1 218533541 7119063 352876..354138 1 NC_011758.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: mrd:Mrad2831_1239 RND family efflux transporter MFP subunit; efflux transporter RND family, MFP subunit 354138 7119063 Mchl_5714 Methylobacterium extorquens CM4 efflux transporter RND family, MFP subunit YP_002424356.1 352876 D 440085 CDS YP_002424357.1 218533542 7119064 354143..357280 1 NC_011758.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: mrd:Mrad2831_1238 CzcA family heavy metal efflux protein; heavy metal efflux pump, CzcA family 357280 7119064 Mchl_5715 Methylobacterium extorquens CM4 heavy metal efflux pump, CzcA family YP_002424357.1 354143 D 440085 CDS YP_002424358.1 218533543 7119065 357273..357608 1 NC_011758.1 hypothetical protein 357608 7119065 Mchl_5716 Methylobacterium extorquens CM4 hypothetical protein YP_002424358.1 357273 D 440085 CDS YP_002424359.1 218533544 7119066 358452..359561 1 NC_011758.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: azo:azo0308 probable phenylacetic acid degradation NADH oxidoreductase PaaE; oxidoreductase FAD/NAD(P)-binding domain protein 359561 7119066 Mchl_5717 Methylobacterium extorquens CM4 oxidoreductase FAD/NAD(P)-binding domain protein YP_002424359.1 358452 D 440085 CDS YP_002424360.1 218533545 7119067 359554..360711 1 NC_011758.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: aeh:Mlg_1275 C4-dicarboxylate transporter/malic acid transport protein; C4-dicarboxylate transporter/malic acid transport protein 360711 7119067 Mchl_5718 Methylobacterium extorquens CM4 C4-dicarboxylate transporter/malic acid transport protein YP_002424360.1 359554 D 440085 CDS YP_002424361.1 218533546 7119068 360898..361890 1 NC_011758.1 KEGG: mmi:MMAR_4261 hypothetical protein; hypothetical protein 361890 7119068 Mchl_5719 Methylobacterium extorquens CM4 hypothetical protein YP_002424361.1 360898 D 440085 CDS YP_002424362.1 218533547 7119069 362249..363580 1 NC_011758.1 PFAM: chemotaxis sensory transducer; KEGG: azc:AZC_0666 chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 363580 7119069 Mchl_5720 Methylobacterium extorquens CM4 methyl-accepting chemotaxis sensory transducer YP_002424362.1 362249 D 440085 CDS YP_002424363.1 218533548 7119070 363577..364188 1 NC_011758.1 PFAM: cobalbumin biosynthesis protein; KEGG: mrd:Mrad2831_1469 adenosylcobinamide-phosphate guanylyltransferase; adenosylcobinamide-phosphate guanylyltransferase 364188 7119070 Mchl_5721 Methylobacterium extorquens CM4 adenosylcobinamide-phosphate guanylyltransferase YP_002424363.1 363577 D 440085 CDS YP_002424364.1 218533549 7119071 364185..364787 1 NC_011758.1 KEGG: mrd:Mrad2831_1470 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; cob(I)alamin adenosyltransferase 364787 7119071 Mchl_5722 Methylobacterium extorquens CM4 cob(I)alamin adenosyltransferase YP_002424364.1 364185 D 440085 CDS YP_002424365.1 218533550 7119072 364822..366276 1 NC_011758.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: mrd:Mrad2831_1471 cobyric acid synthase CobQ; cobyric acid synthase CobQ 366276 7119072 Mchl_5723 Methylobacterium extorquens CM4 cobyric acid synthase CobQ YP_002424365.1 364822 D 440085 CDS YP_002424366.1 218533551 7119073 complement(366284..367276) 1 NC_011758.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; KEGG: mex:Mext_4724 cobalamin biosynthesis protein CobD; cobalamin biosynthesis protein CobD 367276 7119073 Mchl_5724 Methylobacterium extorquens CM4 cobalamin biosynthesis protein CobD YP_002424366.1 366284 R 440085 CDS YP_002424367.1 218533552 7119074 complement(367687..368346) 1 NC_011758.1 PFAM: regulatory protein MerR; KEGG: afe:Lferr_2140 MerR family transcriptional regulator; MerR family transcriptional regulator 368346 7119074 Mchl_5725 Methylobacterium extorquens CM4 MerR family transcriptional regulator YP_002424367.1 367687 R 440085 CDS YP_002424368.1 218533553 7119075 368508..369470 1 NC_011758.1 PFAM: methylenetetrahydrofolate reductase; KEGG: jan:Jann_1978 metfprotein-like; methylenetetrahydrofolate reductase 369470 7119075 Mchl_5726 Methylobacterium extorquens CM4 methylenetetrahydrofolate reductase YP_002424368.1 368508 D 440085 CDS YP_002424369.1 218533554 7119076 369704..370639 1 NC_011758.1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of mtrA; tetrahydromethanopterin S-methyltransferase subunit H 370639 7119076 Mchl_5727 Methylobacterium extorquens CM4 tetrahydromethanopterin S-methyltransferase subunit H YP_002424369.1 369704 D 440085 CDS YP_002424370.1 218533555 7119077 370636..371772 1 NC_011758.1 KEGG: dsy:DSY1510 hypothetical protein; hypothetical protein 371772 7119077 Mchl_5728 Methylobacterium extorquens CM4 hypothetical protein YP_002424370.1 370636 D 440085 CDS YP_002424371.1 218533556 7119078 complement(371887..372972) 1 NC_011758.1 TIGRFAM: cobalamin biosynthesis protein CbiD; PFAM: cobalamin (vitamin B12) biosynthesis CbiD protein; KEGG: met:M446_2454 cobalamin biosynthesis protein CbiD; cobalamin biosynthesis protein CbiD 372972 7119078 Mchl_5729 Methylobacterium extorquens CM4 cobalamin biosynthesis protein CbiD YP_002424371.1 371887 R 440085 CDS YP_002424372.1 218533557 7119079 complement(372969..374528) 1 NC_011758.1 TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: xau:Xaut_5025 aminotransferase class I and II; L-threonine-O-3-phosphate decarboxylase 374528 7119079 Mchl_5730 Methylobacterium extorquens CM4 L-threonine-O-3-phosphate decarboxylase YP_002424372.1 372969 R 440085 CDS YP_002424373.1 218533558 7119080 375103..375906 1 NC_011758.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pla:Plav_1055 uroporphyrin-III C-methyltransferase; uroporphyrin-III C-methyltransferase 375906 7119080 Mchl_5731 Methylobacterium extorquens CM4 uroporphyrin-III C-methyltransferase YP_002424373.1 375103 D 440085 CDS YP_002424374.1 218533559 7119081 375948..376655 1 NC_011758.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: smd:Smed_1562 cob(II)yrinic acid a,c-diamide reductase; cob(II)yrinic acid a,c-diamide reductase 376655 7119081 Mchl_5732 Methylobacterium extorquens CM4 cob(II)yrinic acid a,c-diamide reductase YP_002424374.1 375948 D 440085 CDS YP_002424375.1 218533560 7119083 complement(378297..379097) 1 NC_011758.1 KEGG: mrd:Mrad2831_5261 transmembrane anti-sigma factor; transmembrane anti-sigma factor 379097 7119083 Mchl_5734 Methylobacterium extorquens CM4 transmembrane anti-sigma factor YP_002424375.1 378297 R 440085 CDS YP_002424376.1 218533561 7119084 complement(379094..379606) 1 NC_011758.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: mrd:Mrad2831_5260 ECF subfamily RNA polymerase sigma-24 factor; RNA polymerase, sigma-24 subunit, ECF subfamily 379606 7119084 Mchl_5735 Methylobacterium extorquens CM4 RNA polymerase, sigma-24 subunit, ECF subfamily YP_002424376.1 379094 R 440085 CDS YP_002424377.1 218533562 7119085 379803..380201 1 NC_011758.1 PFAM: protein of unknown function DUF305; KEGG: mrd:Mrad2831_5258 hypothetical protein; hypothetical protein 380201 7119085 Mchl_5736 Methylobacterium extorquens CM4 hypothetical protein YP_002424377.1 379803 D 440085 CDS YP_002424479.1 218534718 7119647 complement(105..884) 1 NC_011760.1 KEGG: mpo:Mpop_5430 hypothetical protein; hypothetical protein 884 7119647 Mchl_5737 Methylobacterium extorquens CM4 hypothetical protein YP_002424479.1 105 R 440085 CDS YP_002424480.1 218534719 7119609 1232..1576 1 NC_011760.1 KEGG: cak:Caul_4863 hypothetical protein; hypothetical protein 1576 7119609 Mchl_5738 Methylobacterium extorquens CM4 hypothetical protein YP_002424480.1 1232 D 440085 CDS YP_002424481.1 218534720 7119610 1580..1993 1 NC_011760.1 KEGG: mpo:Mpop_3482 hypothetical protein; hypothetical protein 1993 7119610 Mchl_5739 Methylobacterium extorquens CM4 hypothetical protein YP_002424481.1 1580 D 440085 CDS YP_002424482.1 218534721 7119611 2105..2536 1 NC_011760.1 KEGG: mrd:Mrad2831_6451 hypothetical protein; hypothetical protein 2536 7119611 Mchl_5740 Methylobacterium extorquens CM4 hypothetical protein YP_002424482.1 2105 D 440085 CDS YP_002424483.1 218534722 7119612 complement(2599..3918) 1 NC_011760.1 KEGG: met:M446_5137 flagellin domain-containing protein; flagellin domain-containing protein 3918 7119612 Mchl_5741 Methylobacterium extorquens CM4 flagellin domain-containing protein YP_002424483.1 2599 R 440085 CDS YP_002424484.1 218534723 7119613 complement(4260..4631) 1 NC_011760.1 KEGG: met:M446_5138 flagellar biosynthesis repressor FlbT; flagellar biosynthesis repressor FlbT 4631 7119613 Mchl_5742 Methylobacterium extorquens CM4 flagellar biosynthesis repressor FlbT YP_002424484.1 4260 R 440085 CDS YP_002424485.1 218534724 7119615 complement(4932..5465) 1 NC_011760.1 KEGG: rec:RHECIAT_CH0001128 hypothetical protein; hypothetical protein 5465 7119615 Mchl_5744 Methylobacterium extorquens CM4 hypothetical protein YP_002424485.1 4932 R 440085 CDS YP_002424486.1 218534725 7119616 5776..6024 1 NC_011760.1 KEGG: mpo:Mpop_5031 hypothetical protein; hypothetical protein 6024 7119616 Mchl_5745 Methylobacterium extorquens CM4 hypothetical protein YP_002424486.1 5776 D 440085 CDS YP_002424487.1 218534726 7119617 6886..7176 1 NC_011760.1 KEGG: mex:Mext_0496 hypothetical protein; hypothetical protein 7176 7119617 Mchl_5746 Methylobacterium extorquens CM4 hypothetical protein YP_002424487.1 6886 D 440085 CDS YP_002424488.1 218534727 7119618 complement(7337..8467) 1 NC_011760.1 KEGG: rle:RL2313 hypothetical protein; hypothetical protein 8467 7119618 Mchl_5747 Methylobacterium extorquens CM4 hypothetical protein YP_002424488.1 7337 R 440085 CDS YP_002424489.1 218534728 7119619 complement(8467..8751) 1 NC_011760.1 hypothetical protein 8751 7119619 Mchl_5748 Methylobacterium extorquens CM4 hypothetical protein YP_002424489.1 8467 R 440085 CDS YP_002424490.1 218534729 7119620 complement(8757..9038) 1 NC_011760.1 KEGG: bbt:BBta_1498 hypothetical protein; hypothetical protein 9038 7119620 Mchl_5749 Methylobacterium extorquens CM4 hypothetical protein YP_002424490.1 8757 R 440085 CDS YP_002424491.1 218534730 7119621 9143..9445 1 NC_011760.1 KEGG: met:M446_3327 hypothetical protein; hypothetical protein 9445 7119621 Mchl_5750 Methylobacterium extorquens CM4 hypothetical protein YP_002424491.1 9143 D 440085 CDS YP_002424492.1 218534731 7119622 9494..9934 1 NC_011760.1 KEGG: bte:BTH_II2324 1A family penicillin-binding protein; 1A family penicillin-binding protein 9934 7119622 Mchl_5751 Methylobacterium extorquens CM4 1A family penicillin-binding protein YP_002424492.1 9494 D 440085 CDS YP_002424493.1 218534732 7119623 10015..10551 1 NC_011760.1 hypothetical protein 10551 7119623 Mchl_5752 Methylobacterium extorquens CM4 hypothetical protein YP_002424493.1 10015 D 440085 CDS YP_002424494.1 218534733 7119624 10598..11338 1 NC_011760.1 hypothetical protein 11338 7119624 Mchl_5753 Methylobacterium extorquens CM4 hypothetical protein YP_002424494.1 10598 D 440085 CDS YP_002424495.1 218534734 7119625 11405..11944 1 NC_011760.1 KEGG: kpn:KPN_01966 electron transport complex protein RnfC; hypothetical protein 11944 7119625 Mchl_5754 Methylobacterium extorquens CM4 hypothetical protein YP_002424495.1 11405 D 440085 CDS YP_002424496.1 218534735 7119626 11948..12226 1 NC_011760.1 KEGG: mex:Mext_2448 hypothetical protein; hypothetical protein 12226 7119626 Mchl_5755 Methylobacterium extorquens CM4 hypothetical protein YP_002424496.1 11948 D 440085 CDS YP_002424497.1 218534736 7119627 complement(12221..12379) 1 NC_011760.1 KEGG: mpo:Mpop_0877 hypothetical protein; hypothetical protein 12379 7119627 Mchl_5756 Methylobacterium extorquens CM4 hypothetical protein YP_002424497.1 12221 R 440085 CDS YP_002424498.1 218534737 7119628 12761..13408 1 NC_011760.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: met:M446_3124 cobyrinic acid ac-diamide synthase; Cobyrinic acid ac-diamide synthase 13408 7119628 Mchl_5757 Methylobacterium extorquens CM4 Cobyrinic acid ac-diamide synthase YP_002424498.1 12761 D 440085 CDS YP_002424499.1 218534738 7119629 13603..13761 1 NC_011760.1 hypothetical protein 13761 7119629 Mchl_5758 Methylobacterium extorquens CM4 hypothetical protein YP_002424499.1 13603 D 440085 CDS YP_002424500.1 218534739 7119630 13772..14074 1 NC_011760.1 hypothetical protein 14074 7119630 Mchl_5759 Methylobacterium extorquens CM4 hypothetical protein YP_002424500.1 13772 D 440085 CDS YP_002424501.1 218534740 7119631 14221..15096 1 NC_011760.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sru:SRU_1506 tyrosine recombinase XerC; integrase family protein 15096 7119631 Mchl_5760 Methylobacterium extorquens CM4 integrase family protein YP_002424501.1 14221 D 440085 CDS YP_002424502.1 218534741 7119633 complement(16035..17297) 1 NC_011760.1 KEGG: mpo:Mpop_1194 conserved hypothetical protein; putative flagellin C-ter domain; conserved hypothetical protein; putative flagellin C-ter domain 17297 7119633 Mchl_5762 Methylobacterium extorquens CM4 conserved hypothetical protein; putative flagellin C-ter domain YP_002424502.1 16035 R 440085 CDS YP_002424503.1 218534742 7119634 17461..17865 1 NC_011760.1 PFAM: flagellar FlbT family protein; KEGG: met:M446_0687 flagellar FlbT family protein; flagellar FlbT family protein 17865 7119634 Mchl_5763 Methylobacterium extorquens CM4 flagellar FlbT family protein YP_002424503.1 17461 D 440085 CDS YP_002424504.1 218534743 7119635 complement(18067..18306) 1 NC_011760.1 hypothetical protein 18306 7119635 Mchl_5764 Methylobacterium extorquens CM4 hypothetical protein YP_002424504.1 18067 R 440085 CDS YP_002424505.1 218534744 7119636 complement(18303..18500) 1 NC_011760.1 hypothetical protein 18500 7119636 Mchl_5765 Methylobacterium extorquens CM4 hypothetical protein YP_002424505.1 18303 R 440085 CDS YP_002424506.1 218534745 7119637 complement(18497..18703) 1 NC_011760.1 hypothetical protein 18703 7119637 Mchl_5766 Methylobacterium extorquens CM4 hypothetical protein YP_002424506.1 18497 R 440085 CDS YP_002424507.1 218534746 7119638 complement(18700..18882) 1 NC_011760.1 hypothetical protein 18882 7119638 Mchl_5767 Methylobacterium extorquens CM4 hypothetical protein YP_002424507.1 18700 R 440085 CDS YP_002424508.1 218534747 7119639 complement(18866..19108) 1 NC_011760.1 hypothetical protein 19108 7119639 Mchl_5768 Methylobacterium extorquens CM4 hypothetical protein YP_002424508.1 18866 R 440085 CDS YP_002424509.1 218534748 7119640 complement(19105..19527) 1 NC_011760.1 KEGG: met:M446_0803 hypothetical protein; hypothetical protein 19527 7119640 Mchl_5769 Methylobacterium extorquens CM4 hypothetical protein YP_002424509.1 19105 R 440085 CDS YP_002424510.1 218534749 7119641 complement(19583..19822) 1 NC_011760.1 hypothetical protein 19822 7119641 Mchl_5770 Methylobacterium extorquens CM4 hypothetical protein YP_002424510.1 19583 R 440085 CDS YP_002424511.1 218534750 7119642 complement(19819..20070) 1 NC_011760.1 KEGG: mex:Mext_1871 hypothetical protein; hypothetical protein 20070 7119642 Mchl_5771 Methylobacterium extorquens CM4 hypothetical protein YP_002424511.1 19819 R 440085 CDS YP_002424512.1 218534751 7119643 complement(20113..20448) 1 NC_011760.1 KEGG: mrd:Mrad2831_1256 hypothetical protein; hypothetical protein 20448 7119643 Mchl_5772 Methylobacterium extorquens CM4 hypothetical protein YP_002424512.1 20113 R 440085 CDS YP_002424513.1 218534752 7119644 complement(20445..20714) 1 NC_011760.1 KEGG: met:M446_0800 hypothetical protein; hypothetical protein 20714 7119644 Mchl_5773 Methylobacterium extorquens CM4 hypothetical protein YP_002424513.1 20445 R 440085 CDS YP_002424514.1 218534753 7119645 complement(20711..22327) 1 NC_011760.1 KEGG: mag:amb0657 hypothetical protein; hypothetical protein 22327 7119645 Mchl_5774 Methylobacterium extorquens CM4 hypothetical protein YP_002424514.1 20711 R 440085 CDS YP_002424515.1 218534754 7119646 complement(22383..22610) 1 NC_011760.1 hypothetical protein 22610 7119646 Mchl_5775 Methylobacterium extorquens CM4 hypothetical protein YP_002424515.1 22383 R 440085 CDS