-- dump date   	20140619_145622
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
979556000001	benzoate transport; Region: 2A0115; TIGR00895
979556000002	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK07899
979556000003	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
979556000004	RNA binding site [nucleotide binding]; other site
979556000005	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
979556000006	RNA binding site [nucleotide binding]; other site
979556000007	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
979556000008	RNA binding site [nucleotide binding]; other site
979556000009	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
979556000010	RNA binding site [nucleotide binding]; other site
979556000011	domain interface; other site
979556000012	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
979556000013	N-acetyl-D-glucosamine binding site [chemical binding]; other site
979556000014	catalytic residue [active]
979556000015	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
979556000016	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
979556000017	ABC1 family; Region: ABC1; cl17513
979556000018	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556000019	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
979556000020	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
979556000021	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
979556000022	active site
979556000023	dimer interface [polypeptide binding]; other site
979556000024	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
979556000025	dimer interface [polypeptide binding]; other site
979556000026	active site
979556000027	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
979556000028	putative active site [active]
979556000029	putative CoA binding site [chemical binding]; other site
979556000030	nudix motif; other site
979556000031	metal binding site [ion binding]; metal-binding site
979556000032	G5 domain; Region: G5; pfam07501
979556000033	Sec-independent protein translocase protein (TatC); Region: TatC; pfam00902
979556000034	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
979556000035	twin arginine-targeting protein translocase, TatA/E family; Region: tatAE; TIGR01411
979556000036	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
979556000037	putative active site [active]
979556000038	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556000039	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
979556000040	active site
979556000041	phosphorylation site [posttranslational modification]
979556000042	intermolecular recognition site; other site
979556000043	dimerization interface [polypeptide binding]; other site
979556000044	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556000045	DNA binding site [nucleotide binding]
979556000046	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556000047	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556000048	dimer interface [polypeptide binding]; other site
979556000049	phosphorylation site [posttranslational modification]
979556000050	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556000051	ATP binding site [chemical binding]; other site
979556000052	Mg2+ binding site [ion binding]; other site
979556000053	G-X-G motif; other site
979556000054	ApbE family; Region: ApbE; pfam02424
979556000055	FMN-binding domain; Region: FMN_bind; cl01081
979556000056	Predicted ferric reductase [Inorganic ion transport and metabolism]; Region: COG4097
979556000057	Ferric reductase like transmembrane component; Region: Ferric_reduct; pfam01794
979556000058	NAD(P) binding domain of  ferredoxin reductase-like proteins catalyze electron transfer between an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) domain, which varies in orientation with respect to the NAD(P)...; Region: FNR_like_3; cd06198
979556000059	FAD binding pocket [chemical binding]; other site
979556000060	FAD binding motif [chemical binding]; other site
979556000061	phosphate binding motif [ion binding]; other site
979556000062	beta-alpha-beta structure motif; other site
979556000063	NAD binding pocket [chemical binding]; other site
979556000064	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556000065	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
979556000066	active site
979556000067	metal binding site [ion binding]; metal-binding site
979556000068	Predicted transcriptional regulator [Transcription]; Region: COG2378
979556000069	HTH domain; Region: HTH_11; pfam08279
979556000070	WYL domain; Region: WYL; pfam13280
979556000071	short chain dehydrogenase; Provisional; Region: PRK06197
979556000072	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556000073	NAD(P) binding site [chemical binding]; other site
979556000074	active site
979556000075	methionine sulfoxide reductase B; Provisional; Region: PRK00222
979556000076	SelR domain; Region: SelR; pfam01641
979556000077	methionine sulfoxide reductase A; Provisional; Region: PRK14054
979556000078	Low molecular weight phosphatase family; Region: LMWPc; cl00105
979556000079	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
979556000080	active site
979556000081	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556000082	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
979556000083	hydroxyglutarate oxidase; Provisional; Region: PRK11728
979556000084	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556000085	Coenzyme A binding pocket [chemical binding]; other site
979556000086	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556000087	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
979556000088	active site
979556000089	rhodanese superfamily protein; Provisional; Region: PRK05320
979556000090	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
979556000091	active site residue [active]
979556000092	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556000093	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
979556000094	active site
979556000095	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556000096	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
979556000097	putative catalytic site [active]
979556000098	putative metal binding site [ion binding]; other site
979556000099	putative phosphate binding site [ion binding]; other site
979556000100	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
979556000101	active site
979556000102	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
979556000103	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
979556000104	tetramer interface [polypeptide binding]; other site
979556000105	heme binding pocket [chemical binding]; other site
979556000106	NADPH binding site [chemical binding]; other site
979556000107	Protein of unknown function (DUF2945); Region: DUF2945; pfam11160
979556000108	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
979556000109	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
979556000110	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
979556000111	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
979556000112	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
979556000113	DNA-binding site [nucleotide binding]; DNA binding site
979556000114	RNA-binding motif; other site
979556000115	Fatty acid desaturase; Region: FA_desaturase; pfam00487
979556000116	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
979556000117	putative di-iron ligands [ion binding]; other site
979556000118	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
979556000119	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
979556000120	active site
979556000121	metal binding site [ion binding]; metal-binding site
979556000122	homotetramer interface [polypeptide binding]; other site
979556000123	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556000124	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556000125	active site
979556000126	phosphorylation site [posttranslational modification]
979556000127	intermolecular recognition site; other site
979556000128	dimerization interface [polypeptide binding]; other site
979556000129	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556000130	DNA binding site [nucleotide binding]
979556000131	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556000132	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
979556000133	dimerization interface [polypeptide binding]; other site
979556000134	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556000135	dimer interface [polypeptide binding]; other site
979556000136	phosphorylation site [posttranslational modification]
979556000137	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556000138	ATP binding site [chemical binding]; other site
979556000139	Mg2+ binding site [ion binding]; other site
979556000140	G-X-G motif; other site
979556000141	VanZ like family; Region: VanZ; pfam04892
979556000142	Protein of unknown function (DUF3054); Region: DUF3054; pfam11255
979556000143	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556000144	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556000145	DNA binding residues [nucleotide binding]
979556000146	ACT domain; Region: ACT_6; pfam13740
979556000147	Glycine cleavage system regulatory protein [Amino acid transport and metabolism]; Region: GcvR; COG2716
979556000148	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_2; cd04869
979556000149	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
979556000150	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
979556000151	Protein of unknown function (DUF2834); Region: DUF2834; pfam11196
979556000152	NADH(P)-binding; Region: NAD_binding_10; pfam13460
979556000153	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
979556000154	NADP binding site [chemical binding]; other site
979556000155	Predicted transcriptional regulators [Transcription]; Region: COG1733
979556000156	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
979556000157	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
979556000158	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
979556000159	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556000160	NADH(P)-binding; Region: NAD_binding_10; pfam13460
979556000161	NAD(P) binding site [chemical binding]; other site
979556000162	active site
979556000163	PPOX class probable F420-dependent enzyme; Region: Rv1155_F420; TIGR03618
979556000164	hypothetical protein; Provisional; Region: PRK04233
979556000165	5'-3' exonuclease, N-terminal resolvase-like domain; Region: 5_3_exonuc_N; pfam02739
979556000166	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
979556000167	active site
979556000168	metal binding site 1 [ion binding]; metal-binding site
979556000169	putative 5' ssDNA interaction site; other site
979556000170	metal binding site 3; metal-binding site
979556000171	metal binding site 2 [ion binding]; metal-binding site
979556000172	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
979556000173	putative DNA binding site [nucleotide binding]; other site
979556000174	putative metal binding site [ion binding]; other site
979556000175	hypothetical protein; Provisional; Region: PRK07945
979556000176	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
979556000177	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
979556000178	active site
979556000179	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
979556000180	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
979556000181	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
979556000182	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
979556000183	Subunit I/III interface [polypeptide binding]; other site
979556000184	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
979556000185	Cytochrome c; Region: Cytochrom_C; pfam00034
979556000186	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
979556000187	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
979556000188	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
979556000189	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
979556000190	iron-sulfur cluster [ion binding]; other site
979556000191	[2Fe-2S] cluster binding site [ion binding]; other site
979556000192	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
979556000193	heme bH binding site [chemical binding]; other site
979556000194	intrachain domain interface; other site
979556000195	heme bL binding site [chemical binding]; other site
979556000196	interchain domain interface [polypeptide binding]; other site
979556000197	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N_2; pfam13631
979556000198	Qo binding site; other site
979556000199	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
979556000200	active site residue [active]
979556000201	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
979556000202	Cytochrome c oxidase subunit IV; Region: Cyt_c_ox_IV; pfam12270
979556000203	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
979556000204	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
979556000205	D-pathway; other site
979556000206	Putative ubiquinol binding site [chemical binding]; other site
979556000207	Low-spin heme (heme b) binding site [chemical binding]; other site
979556000208	Putative water exit pathway; other site
979556000209	Binuclear center (heme o3/CuB) [ion binding]; other site
979556000210	K-pathway; other site
979556000211	Putative proton exit pathway; other site
979556000212	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
979556000213	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
979556000214	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
979556000215	hypothetical protein; Provisional; Region: PRK07907
979556000216	M20 Dipeptidases; Region: M20_Dipept_like; cd03893
979556000217	active site
979556000218	metal binding site [ion binding]; metal-binding site
979556000219	dimer interface [polypeptide binding]; other site
979556000220	Protein of unknown function (DUF3043); Region: DUF3043; pfam11241
979556000221	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
979556000222	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
979556000223	quinone interaction residues [chemical binding]; other site
979556000224	active site
979556000225	catalytic residues [active]
979556000226	FMN binding site [chemical binding]; other site
979556000227	substrate binding site [chemical binding]; other site
979556000228	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
979556000229	ATP cone domain; Region: ATP-cone; pfam03477
979556000230	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
979556000231	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
979556000232	NAD binding site [chemical binding]; other site
979556000233	dimerization interface [polypeptide binding]; other site
979556000234	product binding site; other site
979556000235	substrate binding site [chemical binding]; other site
979556000236	zinc binding site [ion binding]; other site
979556000237	catalytic residues [active]
979556000238	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
979556000239	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
979556000240	active site
979556000241	PHP Thumb interface [polypeptide binding]; other site
979556000242	metal binding site [ion binding]; metal-binding site
979556000243	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
979556000244	generic binding surface II; other site
979556000245	generic binding surface I; other site
979556000246	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
979556000247	nudix motif; other site
979556000248	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
979556000249	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556000250	RNA binding surface [nucleotide binding]; other site
979556000251	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
979556000252	active site
979556000253	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
979556000254	DivIVA protein; Region: DivIVA; pfam05103
979556000255	DivIVA domain; Region: DivI1A_domain; TIGR03544
979556000256	YGGT family; Region: YGGT; cl00508
979556000257	Protein of unknown function (DUF552); Region: DUF552; cl00775
979556000258	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
979556000259	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
979556000260	catalytic residue [active]
979556000261	cell division protein FtsZ; Validated; Region: PRK09330
979556000262	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
979556000263	nucleotide binding site [chemical binding]; other site
979556000264	SulA interaction site; other site
979556000265	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
979556000266	Cell division protein FtsQ; Region: FtsQ; pfam03799
979556000267	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
979556000268	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
979556000269	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
979556000270	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
979556000271	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
979556000272	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
979556000273	homodimer interface [polypeptide binding]; other site
979556000274	active site
979556000275	cell division protein FtsW; Region: ftsW; TIGR02614
979556000276	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01438
979556000277	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
979556000278	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
979556000279	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
979556000280	Mg++ binding site [ion binding]; other site
979556000281	putative catalytic motif [active]
979556000282	putative substrate binding site [chemical binding]; other site
979556000283	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
979556000284	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
979556000285	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
979556000286	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
979556000287	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
979556000288	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
979556000289	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
979556000290	MraW methylase family; Region: Methyltransf_5; cl17771
979556000291	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
979556000292	cell division protein MraZ; Reviewed; Region: PRK00326
979556000293	MraZ protein; Region: MraZ; pfam02381
979556000294	MraZ protein; Region: MraZ; pfam02381
979556000295	Protein of unknown function (DUF3040); Region: DUF3040; pfam11239
979556000296	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
979556000297	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
979556000298	substrate binding pocket [chemical binding]; other site
979556000299	chain length determination region; other site
979556000300	substrate-Mg2+ binding site; other site
979556000301	catalytic residues [active]
979556000302	aspartate-rich region 1; other site
979556000303	active site lid residues [active]
979556000304	aspartate-rich region 2; other site
979556000305	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
979556000306	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
979556000307	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556000308	Catalytic domain of Protein Kinases; Region: PKc; cd00180
979556000309	active site
979556000310	ATP binding site [chemical binding]; other site
979556000311	substrate binding site [chemical binding]; other site
979556000312	activation loop (A-loop); other site
979556000313	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
979556000314	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556000315	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556000316	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556000317	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
979556000318	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
979556000319	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
979556000320	putative acyl-acceptor binding pocket; other site
979556000321	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
979556000322	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556000323	nucleotide binding site [chemical binding]; other site
979556000324	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
979556000325	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
979556000326	acyl-activating enzyme (AAE) consensus motif; other site
979556000327	putative AMP binding site [chemical binding]; other site
979556000328	putative active site [active]
979556000329	putative CoA binding site [chemical binding]; other site
979556000330	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
979556000331	active site
979556000332	catalytic residues [active]
979556000333	metal binding site [ion binding]; metal-binding site
979556000334	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556000335	AAA domain; Region: AAA_31; pfam13614
979556000336	pyruvate carboxylase; Reviewed; Region: PRK12999
979556000337	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
979556000338	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556000339	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
979556000340	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
979556000341	active site
979556000342	catalytic residues [active]
979556000343	metal binding site [ion binding]; metal-binding site
979556000344	homodimer binding site [polypeptide binding]; other site
979556000345	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
979556000346	carboxyltransferase (CT) interaction site; other site
979556000347	biotinylation site [posttranslational modification]; other site
979556000348	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
979556000349	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
979556000350	Magnesium ion binding site [ion binding]; other site
979556000351	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
979556000352	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
979556000353	DNA binding residues [nucleotide binding]
979556000354	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
979556000355	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556000356	DNA binding residues [nucleotide binding]
979556000357	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
979556000358	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
979556000359	phosphopeptide binding site; other site
979556000360	CopC domain; Region: CopC; pfam04234
979556000361	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK07818
979556000362	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556000363	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
979556000364	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cd07374
979556000365	putative active site; other site
979556000366	putative metal binding residues [ion binding]; other site
979556000367	signature motif; other site
979556000368	putative triphosphate binding site [ion binding]; other site
979556000369	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
979556000370	catalytic triad [active]
979556000371	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
979556000372	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
979556000373	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
979556000374	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
979556000375	active site
979556000376	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556000377	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556000378	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
979556000379	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
979556000380	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
979556000381	CBD_II domain; Region: CBD_II; smart00637
979556000382	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
979556000383	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
979556000384	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
979556000385	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
979556000386	NAD(P) binding site [chemical binding]; other site
979556000387	catalytic residues [active]
979556000388	hypothetical protein; Provisional; Region: PRK06062
979556000389	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556000390	inhibitor-cofactor binding pocket; inhibition site
979556000391	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556000392	catalytic residue [active]
979556000393	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
979556000394	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
979556000395	tetrameric interface [polypeptide binding]; other site
979556000396	NAD binding site [chemical binding]; other site
979556000397	catalytic residues [active]
979556000398	substrate binding site [chemical binding]; other site
979556000399	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
979556000400	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
979556000401	putative DNA binding site [nucleotide binding]; other site
979556000402	putative Zn2+ binding site [ion binding]; other site
979556000403	AsnC family; Region: AsnC_trans_reg; pfam01037
979556000404	hypothetical protein; Provisional; Region: PRK06541
979556000405	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556000406	inhibitor-cofactor binding pocket; inhibition site
979556000407	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556000408	catalytic residue [active]
979556000409	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556000410	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
979556000411	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556000412	non-specific DNA binding site [nucleotide binding]; other site
979556000413	salt bridge; other site
979556000414	sequence-specific DNA binding site [nucleotide binding]; other site
979556000415	Cupin domain; Region: Cupin_2; pfam07883
979556000416	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556000417	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556000418	Walker A/P-loop; other site
979556000419	ATP binding site [chemical binding]; other site
979556000420	Q-loop/lid; other site
979556000421	ABC transporter signature motif; other site
979556000422	Walker B; other site
979556000423	D-loop; other site
979556000424	H-loop/switch region; other site
979556000425	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556000426	Walker A/P-loop; other site
979556000427	ATP binding site [chemical binding]; other site
979556000428	Q-loop/lid; other site
979556000429	ABC transporter signature motif; other site
979556000430	Walker B; other site
979556000431	D-loop; other site
979556000432	H-loop/switch region; other site
979556000433	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556000434	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
979556000435	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556000436	dimer interface [polypeptide binding]; other site
979556000437	conserved gate region; other site
979556000438	putative PBP binding loops; other site
979556000439	ABC-ATPase subunit interface; other site
979556000440	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556000441	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556000442	dimer interface [polypeptide binding]; other site
979556000443	conserved gate region; other site
979556000444	putative PBP binding loops; other site
979556000445	ABC-ATPase subunit interface; other site
979556000446	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556000447	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_11; cd08516
979556000448	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
979556000449	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
979556000450	Protein of unknown function (DUF3375); Region: DUF3375; pfam11855
979556000451	Domain of unknown function (DUF4194); Region: DUF4194; pfam13835
979556000452	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4913
979556000453	P-loop containing region of AAA domain; Region: AAA_29; pfam13555
979556000454	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
979556000455	Domain of unknown function (DUF222); Region: DUF222; pfam02720
979556000456	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556000457	active site
979556000458	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
979556000459	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
979556000460	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556000461	DNA-binding site [nucleotide binding]; DNA binding site
979556000462	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556000463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556000464	homodimer interface [polypeptide binding]; other site
979556000465	catalytic residue [active]
979556000466	Peptidase domain in the S53 family; Region: Peptidases_S53_like; cd05562
979556000467	putative active site [active]
979556000468	putative catalytic triad [active]
979556000469	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
979556000470	catalytic residues [active]
979556000471	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
979556000472	Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3458
979556000473	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556000474	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556000475	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
979556000476	TM-ABC transporter signature motif; other site
979556000477	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
979556000478	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556000479	TM-ABC transporter signature motif; other site
979556000480	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
979556000481	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
979556000482	Walker A/P-loop; other site
979556000483	ATP binding site [chemical binding]; other site
979556000484	Q-loop/lid; other site
979556000485	ABC transporter signature motif; other site
979556000486	Walker B; other site
979556000487	D-loop; other site
979556000488	H-loop/switch region; other site
979556000489	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
979556000490	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
979556000491	Walker A/P-loop; other site
979556000492	ATP binding site [chemical binding]; other site
979556000493	Q-loop/lid; other site
979556000494	ABC transporter signature motif; other site
979556000495	Walker B; other site
979556000496	D-loop; other site
979556000497	H-loop/switch region; other site
979556000498	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
979556000499	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556000500	AAA ATPase domain; Region: AAA_16; pfam13191
979556000501	Predicted ATPase [General function prediction only]; Region: COG3903
979556000502	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556000503	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556000504	DNA binding residues [nucleotide binding]
979556000505	dimerization interface [polypeptide binding]; other site
979556000506	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
979556000507	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556000508	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
979556000509	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
979556000510	NAD(P) binding site [chemical binding]; other site
979556000511	catalytic residues [active]
979556000512	Benzyl alcohol dehydrogenase; Region: benzyl_alcohol_DH; cd08278
979556000513	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
979556000514	catalytic Zn binding site [ion binding]; other site
979556000515	NAD binding site [chemical binding]; other site
979556000516	structural Zn binding site [ion binding]; other site
979556000517	Ion transport protein; Region: Ion_trans; pfam00520
979556000518	Ion channel; Region: Ion_trans_2; pfam07885
979556000519	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
979556000520	siderophore binding site; other site
979556000521	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
979556000522	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556000523	ABC-ATPase subunit  interface; other site
979556000524	dimer interface [polypeptide binding]; other site
979556000525	putative PBP binding regions; other site
979556000526	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556000527	ABC-ATPase subunit  interface; other site
979556000528	dimer interface [polypeptide binding]; other site
979556000529	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
979556000530	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
979556000531	Walker A/P-loop; other site
979556000532	ATP binding site [chemical binding]; other site
979556000533	Q-loop/lid; other site
979556000534	ABC transporter signature motif; other site
979556000535	Walker B; other site
979556000536	D-loop; other site
979556000537	H-loop/switch region; other site
979556000538	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
979556000539	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
979556000540	FAD binding pocket [chemical binding]; other site
979556000541	FAD binding motif [chemical binding]; other site
979556000542	phosphate binding motif [ion binding]; other site
979556000543	NAD binding pocket [chemical binding]; other site
979556000544	amidase; Provisional; Region: PRK08137
979556000545	Amidase; Region: Amidase; cl11426
979556000546	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
979556000547	dockerin binding interface; other site
979556000548	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
979556000549	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
979556000550	active site
979556000551	active site
979556000552	pyruvate dehydrogenase; Provisional; Region: PRK09124
979556000553	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
979556000554	PYR/PP interface [polypeptide binding]; other site
979556000555	tetramer interface [polypeptide binding]; other site
979556000556	dimer interface [polypeptide binding]; other site
979556000557	TPP binding site [chemical binding]; other site
979556000558	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
979556000559	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
979556000560	TPP-binding site [chemical binding]; other site
979556000561	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
979556000562	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556000563	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
979556000564	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556000565	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
979556000566	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556000567	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556000568	active site
979556000569	phosphorylation site [posttranslational modification]
979556000570	intermolecular recognition site; other site
979556000571	dimerization interface [polypeptide binding]; other site
979556000572	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556000573	DNA binding residues [nucleotide binding]
979556000574	dimerization interface [polypeptide binding]; other site
979556000575	Histidine kinase; Region: HisKA_3; pfam07730
979556000576	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
979556000577	ATP binding site [chemical binding]; other site
979556000578	Mg2+ binding site [ion binding]; other site
979556000579	G-X-G motif; other site
979556000580	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556000581	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556000582	Walker A/P-loop; other site
979556000583	ATP binding site [chemical binding]; other site
979556000584	Q-loop/lid; other site
979556000585	ABC transporter signature motif; other site
979556000586	Walker B; other site
979556000587	D-loop; other site
979556000588	H-loop/switch region; other site
979556000589	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
979556000590	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
979556000591	FtsX-like permease family; Region: FtsX; pfam02687
979556000592	hypothetical protein; Provisional; Region: PRK02237
979556000593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4307
979556000594	Uncharacterized protein conserved in bacteria (DUF2248); Region: DUF2248; pfam10005
979556000595	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556000596	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556000597	active site
979556000598	phosphorylation site [posttranslational modification]
979556000599	intermolecular recognition site; other site
979556000600	dimerization interface [polypeptide binding]; other site
979556000601	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556000602	DNA binding residues [nucleotide binding]
979556000603	Histidine kinase; Region: HisKA_3; pfam07730
979556000604	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
979556000605	ATP binding site [chemical binding]; other site
979556000606	Mg2+ binding site [ion binding]; other site
979556000607	G-X-G motif; other site
979556000608	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556000609	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556000610	DNA-binding site [nucleotide binding]; DNA binding site
979556000611	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
979556000612	2-isopropylmalate synthase; Validated; Region: PRK03739
979556000613	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
979556000614	active site
979556000615	catalytic residues [active]
979556000616	metal binding site [ion binding]; metal-binding site
979556000617	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
979556000618	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556000619	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556000620	NAD(P) binding site [chemical binding]; other site
979556000621	active site
979556000622	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556000623	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556000624	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
979556000625	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
979556000626	tetramer interface [polypeptide binding]; other site
979556000627	TPP-binding site [chemical binding]; other site
979556000628	heterodimer interface [polypeptide binding]; other site
979556000629	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
979556000630	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
979556000631	alpha subunit interface [polypeptide binding]; other site
979556000632	TPP binding site [chemical binding]; other site
979556000633	heterodimer interface [polypeptide binding]; other site
979556000634	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
979556000635	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
979556000636	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
979556000637	E3 interaction surface; other site
979556000638	lipoyl attachment site [posttranslational modification]; other site
979556000639	e3 binding domain; Region: E3_binding; pfam02817
979556000640	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
979556000641	MarR family; Region: MarR_2; cl17246
979556000642	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
979556000643	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
979556000644	Catalytic site [active]
979556000645	Protein of unknown function (Hypoth_ymh); Region: Hypoth_Ymh; pfam09509
979556000646	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
979556000647	DNA binding site [nucleotide binding]
979556000648	active site
979556000649	Int/Topo IB signature motif; other site
979556000650	radical SAM/SPASM domain, FxsB family; Region: SAM_SPASM_FxsB; TIGR04269
979556000651	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556000652	DNA binding residues [nucleotide binding]
979556000653	head completion protein; Provisional; Region: 4; PHA02552
979556000654	Protein of unknown function (DUF3892); Region: DUF3892; pfam13031
979556000655	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
979556000656	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
979556000657	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
979556000658	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556000659	ATP binding site [chemical binding]; other site
979556000660	Mg2+ binding site [ion binding]; other site
979556000661	G-X-G motif; other site
979556000662	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
979556000663	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
979556000664	cofactor binding site; other site
979556000665	DNA binding site [nucleotide binding]
979556000666	substrate interaction site [chemical binding]; other site
979556000667	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
979556000668	additional DNA contacts [nucleotide binding]; other site
979556000669	mismatch recognition site; other site
979556000670	active site
979556000671	zinc binding site [ion binding]; other site
979556000672	DNA intercalation site [nucleotide binding]; other site
979556000673	Abortive infection C-terminus; Region: Abi_C; pfam14355
979556000674	Family description; Region: UvrD_C_2; pfam13538
979556000675	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
979556000676	active site
979556000677	catalytic residues [active]
979556000678	Int/Topo IB signature motif; other site
979556000679	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556000680	Coenzyme A binding pocket [chemical binding]; other site
979556000681	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556000682	RNA binding surface [nucleotide binding]; other site
979556000683	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
979556000684	nudix motif; other site
979556000685	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
979556000686	Protein of unknown function (DUF805); Region: DUF805; pfam05656
979556000687	GTP-binding protein Der; Reviewed; Region: PRK03003
979556000688	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
979556000689	G1 box; other site
979556000690	GTP/Mg2+ binding site [chemical binding]; other site
979556000691	Switch I region; other site
979556000692	G2 box; other site
979556000693	Switch II region; other site
979556000694	G3 box; other site
979556000695	G4 box; other site
979556000696	G5 box; other site
979556000697	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
979556000698	G1 box; other site
979556000699	GTP/Mg2+ binding site [chemical binding]; other site
979556000700	Switch I region; other site
979556000701	G2 box; other site
979556000702	G3 box; other site
979556000703	Switch II region; other site
979556000704	G4 box; other site
979556000705	G5 box; other site
979556000706	cytidylate kinase; Provisional; Region: cmk; PRK00023
979556000707	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
979556000708	CMP-binding site; other site
979556000709	The sites determining sugar specificity; other site
979556000710	prephenate dehydrogenase; Validated; Region: PRK06545
979556000711	prephenate dehydrogenase; Validated; Region: PRK08507
979556000712	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
979556000713	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
979556000714	active site
979556000715	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
979556000716	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
979556000717	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
979556000718	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
979556000719	P-loop; other site
979556000720	Magnesium ion binding site [ion binding]; other site
979556000721	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
979556000722	Magnesium ion binding site [ion binding]; other site
979556000723	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556000724	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cl16915
979556000725	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
979556000726	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
979556000727	active site
979556000728	HIGH motif; other site
979556000729	dimer interface [polypeptide binding]; other site
979556000730	KMSKS motif; other site
979556000731	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556000732	RNA binding surface [nucleotide binding]; other site
979556000733	argininosuccinate lyase; Provisional; Region: PRK00855
979556000734	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
979556000735	active sites [active]
979556000736	tetramer interface [polypeptide binding]; other site
979556000737	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
979556000738	ornithine carbamoyltransferase; Provisional; Region: PRK00779
979556000739	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
979556000740	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
979556000741	acetylornithine aminotransferase; Provisional; Region: argD; PRK03244
979556000742	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556000743	inhibitor-cofactor binding pocket; inhibition site
979556000744	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556000745	catalytic residue [active]
979556000746	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
979556000747	feedback inhibition sensing region; other site
979556000748	homohexameric interface [polypeptide binding]; other site
979556000749	nucleotide binding site [chemical binding]; other site
979556000750	N-acetyl-L-glutamate binding site [chemical binding]; other site
979556000751	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
979556000752	heterotetramer interface [polypeptide binding]; other site
979556000753	active site pocket [active]
979556000754	cleavage site
979556000755	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
979556000756	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
979556000757	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
979556000758	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
979556000759	putative tRNA-binding site [nucleotide binding]; other site
979556000760	B3/4 domain; Region: B3_4; pfam03483
979556000761	tRNA synthetase B5 domain; Region: B5; smart00874
979556000762	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
979556000763	dimer interface [polypeptide binding]; other site
979556000764	motif 1; other site
979556000765	motif 3; other site
979556000766	motif 2; other site
979556000767	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
979556000768	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
979556000769	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
979556000770	dimer interface [polypeptide binding]; other site
979556000771	motif 1; other site
979556000772	active site
979556000773	motif 2; other site
979556000774	motif 3; other site
979556000775	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556000776	dimer interface [polypeptide binding]; other site
979556000777	conserved gate region; other site
979556000778	putative PBP binding loops; other site
979556000779	ABC-ATPase subunit interface; other site
979556000780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556000781	putative PBP binding loops; other site
979556000782	dimer interface [polypeptide binding]; other site
979556000783	ABC-ATPase subunit interface; other site
979556000784	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
979556000785	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
979556000786	substrate binding pocket [chemical binding]; other site
979556000787	membrane-bound complex binding site; other site
979556000788	hinge residues; other site
979556000789	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
979556000790	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
979556000791	Walker A/P-loop; other site
979556000792	ATP binding site [chemical binding]; other site
979556000793	Q-loop/lid; other site
979556000794	ABC transporter signature motif; other site
979556000795	Walker B; other site
979556000796	D-loop; other site
979556000797	H-loop/switch region; other site
979556000798	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
979556000799	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
979556000800	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
979556000801	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
979556000802	23S rRNA binding site [nucleotide binding]; other site
979556000803	L21 binding site [polypeptide binding]; other site
979556000804	L13 binding site [polypeptide binding]; other site
979556000805	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
979556000806	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
979556000807	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
979556000808	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
979556000809	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
979556000810	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
979556000811	catalytic residues [active]
979556000812	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
979556000813	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
979556000814	putative active site [active]
979556000815	oxyanion strand; other site
979556000816	catalytic triad [active]
979556000817	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
979556000818	putative active site pocket [active]
979556000819	4-fold oligomerization interface [polypeptide binding]; other site
979556000820	metal binding residues [ion binding]; metal-binding site
979556000821	3-fold/trimer interface [polypeptide binding]; other site
979556000822	histidinol-phosphate aminotransferase; Provisional; Region: PRK03317
979556000823	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556000824	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556000825	homodimer interface [polypeptide binding]; other site
979556000826	catalytic residue [active]
979556000827	LysM domain; Region: LysM; pfam01476
979556000828	LexA repressor; Validated; Region: PRK00215
979556000829	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
979556000830	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
979556000831	Catalytic site [active]
979556000832	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
979556000833	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
979556000834	Predicted ATPase [General function prediction only]; Region: COG1485
979556000835	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556000836	Walker A motif; other site
979556000837	ATP binding site [chemical binding]; other site
979556000838	Walker B motif; other site
979556000839	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
979556000840	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
979556000841	HflX GTPase family; Region: HflX; cd01878
979556000842	G1 box; other site
979556000843	GTP/Mg2+ binding site [chemical binding]; other site
979556000844	Switch I region; other site
979556000845	G2 box; other site
979556000846	G3 box; other site
979556000847	Switch II region; other site
979556000848	G4 box; other site
979556000849	G5 box; other site
979556000850	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556000851	S-adenosylmethionine binding site [chemical binding]; other site
979556000852	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
979556000853	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
979556000854	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
979556000855	putative acetyltransferase; Provisional; Region: PRK03624
979556000856	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556000857	Coenzyme A binding pocket [chemical binding]; other site
979556000858	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
979556000859	IPP transferase; Region: IPPT; pfam01715
979556000860	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14326
979556000861	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
979556000862	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
979556000863	FeS/SAM binding site; other site
979556000864	TRAM domain; Region: TRAM; cl01282
979556000865	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556000866	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556000867	DNA binding residues [nucleotide binding]
979556000868	dimerization interface [polypeptide binding]; other site
979556000869	RecX family; Region: RecX; pfam02631
979556000870	recombinase A; Provisional; Region: recA; PRK09354
979556000871	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
979556000872	hexamer interface [polypeptide binding]; other site
979556000873	Walker A motif; other site
979556000874	ATP binding site [chemical binding]; other site
979556000875	Walker B motif; other site
979556000876	Protein of unknown function (DUF3046); Region: DUF3046; pfam11248
979556000877	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556000878	non-specific DNA binding site [nucleotide binding]; other site
979556000879	salt bridge; other site
979556000880	sequence-specific DNA binding site [nucleotide binding]; other site
979556000881	Competence-damaged protein; Region: CinA; pfam02464
979556000882	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
979556000883	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
979556000884	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
979556000885	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
979556000886	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556000887	Coenzyme A binding pocket [chemical binding]; other site
979556000888	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
979556000889	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
979556000890	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
979556000891	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
979556000892	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
979556000893	dimer interface [polypeptide binding]; other site
979556000894	active site
979556000895	catalytic residue [active]
979556000896	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
979556000897	dimer interface [polypeptide binding]; other site
979556000898	ADP-ribose binding site [chemical binding]; other site
979556000899	active site
979556000900	nudix motif; other site
979556000901	metal binding site [ion binding]; metal-binding site
979556000902	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
979556000903	classical (c) SDRs; Region: SDR_c; cd05233
979556000904	NAD(P) binding site [chemical binding]; other site
979556000905	active site
979556000906	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
979556000907	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
979556000908	folate binding site [chemical binding]; other site
979556000909	NADP+ binding site [chemical binding]; other site
979556000910	thymidylate synthase; Reviewed; Region: thyA; PRK01827
979556000911	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
979556000912	dimerization interface [polypeptide binding]; other site
979556000913	active site
979556000914	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
979556000915	catalytic residues [active]
979556000916	Domain of unknown function (DUF4395); Region: DUF4395; pfam14340
979556000917	OsmC-like protein; Region: OsmC; cl00767
979556000918	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556000919	TIGR01777 family protein; Region: yfcH
979556000920	NAD(P) binding site [chemical binding]; other site
979556000921	active site
979556000922	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
979556000923	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
979556000924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556000925	S-adenosylmethionine binding site [chemical binding]; other site
979556000926	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556000927	catalytic core [active]
979556000928	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556000929	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556000930	active site
979556000931	catalytic tetrad [active]
979556000932	guanosine pentaphosphate synthetase I/polynucleotide phosphorylase; Region: pppGpp_PNP; TIGR02696
979556000933	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
979556000934	oligomer interface [polypeptide binding]; other site
979556000935	RNA binding site [nucleotide binding]; other site
979556000936	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
979556000937	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
979556000938	RNase E interface [polypeptide binding]; other site
979556000939	trimer interface [polypeptide binding]; other site
979556000940	active site
979556000941	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
979556000942	putative nucleic acid binding region [nucleotide binding]; other site
979556000943	G-X-X-G motif; other site
979556000944	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
979556000945	RNA binding site [nucleotide binding]; other site
979556000946	domain interface; other site
979556000947	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
979556000948	N-acetyl-D-glucosamine binding site [chemical binding]; other site
979556000949	catalytic residue [active]
979556000950	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556000951	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
979556000952	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
979556000953	active site
979556000954	catalytic triad [active]
979556000955	oxyanion hole [active]
979556000956	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
979556000957	Fructosamine kinase; Region: Fructosamin_kin; cl17579
979556000958	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
979556000959	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
979556000960	active site
979556000961	substrate binding site [chemical binding]; other site
979556000962	Mg2+ binding site [ion binding]; other site
979556000963	Methyltransferase domain; Region: Methyltransf_23; pfam13489
979556000964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556000965	S-adenosylmethionine binding site [chemical binding]; other site
979556000966	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
979556000967	LLM-partnered FMN reductase, CE1759 family; Region: LLM_duo_CE1759; TIGR04037
979556000968	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
979556000969	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556000970	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556000971	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
979556000972	Acyltransferase family; Region: Acyl_transf_3; pfam01757
979556000973	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
979556000974	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
979556000975	Predicted periplasmic lipoprotein involved in iron transport [Inorganic ion transport and metabolism]; Region: COG2822
979556000976	Imelysin; Region: Peptidase_M75; pfam09375
979556000977	Iron permease FTR1 family; Region: FTR1; cl00475
979556000978	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
979556000979	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
979556000980	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
979556000981	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
979556000982	16S/18S rRNA binding site [nucleotide binding]; other site
979556000983	S13e-L30e interaction site [polypeptide binding]; other site
979556000984	25S rRNA binding site [nucleotide binding]; other site
979556000985	Uncharacterized ACR, YggU family COG1872; Region: DUF167; pfam02594
979556000986	enterobactin exporter EntS; Provisional; Region: PRK10489
979556000987	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
979556000988	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
979556000989	molybdopterin cofactor binding site; other site
979556000990	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
979556000991	molybdopterin cofactor binding site; other site
979556000992	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
979556000993	EamA-like transporter family; Region: EamA; pfam00892
979556000994	Uncharacterized conserved protein [Function unknown]; Region: COG2353
979556000995	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
979556000996	Protease prsW family; Region: PrsW-protease; pfam13367
979556000997	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556000998	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556000999	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
979556001000	Aspartase; Region: Aspartase; cd01357
979556001001	active sites [active]
979556001002	tetramer interface [polypeptide binding]; other site
979556001003	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
979556001004	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
979556001005	active site
979556001006	metal binding site [ion binding]; metal-binding site
979556001007	hexamer interface [polypeptide binding]; other site
979556001008	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
979556001009	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
979556001010	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
979556001011	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
979556001012	phosphofructokinase; Region: PFK_mixed; TIGR02483
979556001013	active site
979556001014	ADP/pyrophosphate binding site [chemical binding]; other site
979556001015	dimerization interface [polypeptide binding]; other site
979556001016	allosteric effector site; other site
979556001017	fructose-1,6-bisphosphate binding site; other site
979556001018	DEAD-like helicases superfamily; Region: DEXDc; smart00487
979556001019	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556001020	ATP binding site [chemical binding]; other site
979556001021	putative Mg++ binding site [ion binding]; other site
979556001022	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556001023	nucleotide binding region [chemical binding]; other site
979556001024	ATP-binding site [chemical binding]; other site
979556001025	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
979556001026	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
979556001027	metal-binding site [ion binding]
979556001028	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
979556001029	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
979556001030	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
979556001031	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556001032	putative substrate translocation pore; other site
979556001033	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
979556001034	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
979556001035	active site
979556001036	Riboflavin kinase; Region: Flavokinase; smart00904
979556001037	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK03287
979556001038	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
979556001039	RNA binding site [nucleotide binding]; other site
979556001040	active site
979556001041	tRNA Pseudouridine synthase II, C terminal; Region: TruB_C; pfam09142
979556001042	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
979556001043	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
979556001044	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
979556001045	minor groove reading motif; other site
979556001046	helix-hairpin-helix signature motif; other site
979556001047	active site
979556001048	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
979556001049	CAAX protease self-immunity; Region: Abi; pfam02517
979556001050	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
979556001051	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
979556001052	translation initiation factor IF-2; Region: IF-2; TIGR00487
979556001053	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
979556001054	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
979556001055	G1 box; other site
979556001056	putative GEF interaction site [polypeptide binding]; other site
979556001057	GTP/Mg2+ binding site [chemical binding]; other site
979556001058	Switch I region; other site
979556001059	G2 box; other site
979556001060	G3 box; other site
979556001061	Switch II region; other site
979556001062	G4 box; other site
979556001063	G5 box; other site
979556001064	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
979556001065	Translation-initiation factor 2; Region: IF-2; pfam11987
979556001066	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
979556001067	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
979556001068	NusA N-terminal domain; Region: NusA_N; pfam08529
979556001069	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
979556001070	RNA binding site [nucleotide binding]; other site
979556001071	homodimer interface [polypeptide binding]; other site
979556001072	NusA-like KH domain; Region: KH_5; pfam13184
979556001073	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
979556001074	G-X-X-G motif; other site
979556001075	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
979556001076	Zn2+ binding site [ion binding]; other site
979556001077	Mg2+ binding site [ion binding]; other site
979556001078	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
979556001079	homodimer interface [polypeptide binding]; other site
979556001080	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
979556001081	active site pocket [active]
979556001082	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
979556001083	Secretory lipase; Region: LIP; pfam03583
979556001084	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556001085	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556001086	active site
979556001087	catalytic tetrad [active]
979556001088	prolyl-tRNA synthetase; Provisional; Region: PRK09194
979556001089	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
979556001090	dimer interface [polypeptide binding]; other site
979556001091	motif 1; other site
979556001092	active site
979556001093	motif 2; other site
979556001094	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
979556001095	putative deacylase active site [active]
979556001096	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
979556001097	active site
979556001098	motif 3; other site
979556001099	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
979556001100	anticodon binding site; other site
979556001101	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556001102	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556001103	DNA binding residues [nucleotide binding]
979556001104	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556001105	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556001106	DNA binding residues [nucleotide binding]
979556001107	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
979556001108	putative substrate binding pocket [chemical binding]; other site
979556001109	AC domain interface; other site
979556001110	catalytic triad [active]
979556001111	AB domain interface; other site
979556001112	interchain disulfide; other site
979556001113	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
979556001114	benzoate transporter; Region: benE; TIGR00843
979556001115	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
979556001116	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
979556001117	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
979556001118	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
979556001119	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
979556001120	Glutamine amidotransferase class-I; Region: GATase; pfam00117
979556001121	glutamine binding [chemical binding]; other site
979556001122	catalytic triad [active]
979556001123	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
979556001124	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
979556001125	active site
979556001126	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
979556001127	protein binding site [polypeptide binding]; other site
979556001128	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cd05709
979556001129	putative substrate binding region [chemical binding]; other site
979556001130	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
979556001131	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
979556001132	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
979556001133	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
979556001134	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556001135	DNA binding residues [nucleotide binding]
979556001136	drug binding residues [chemical binding]; other site
979556001137	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
979556001138	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
979556001139	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
979556001140	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
979556001141	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
979556001142	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
979556001143	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
979556001144	putative acyl-acceptor binding pocket; other site
979556001145	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
979556001146	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
979556001147	DAK2 domain; Region: Dak2; cl03685
979556001148	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
979556001149	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
979556001150	regulatory protein interface [polypeptide binding]; other site
979556001151	active site
979556001152	regulatory phosphorylation site [posttranslational modification]; other site
979556001153	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
979556001154	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
979556001155	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
979556001156	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556001157	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
979556001158	amphipathic channel; other site
979556001159	Asn-Pro-Ala signature motifs; other site
979556001160	glycerol kinase; Provisional; Region: glpK; PRK00047
979556001161	Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CsGK_like; cd07789
979556001162	N- and C-terminal domain interface [polypeptide binding]; other site
979556001163	active site
979556001164	MgATP binding site [chemical binding]; other site
979556001165	catalytic site [active]
979556001166	metal binding site [ion binding]; metal-binding site
979556001167	putative homotetramer interface [polypeptide binding]; other site
979556001168	glycerol binding site [chemical binding]; other site
979556001169	homodimer interface [polypeptide binding]; other site
979556001170	OsmC-like protein; Region: OsmC; cl00767
979556001171	L-asparaginase II; Region: Asparaginase_II; pfam06089
979556001172	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556001173	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
979556001174	active site
979556001175	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556001176	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556001177	active site
979556001178	catalytic tetrad [active]
979556001179	Protein of unknown function (DUF328); Region: DUF328; cl01143
979556001180	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
979556001181	gamma subunit interface [polypeptide binding]; other site
979556001182	epsilon subunit interface [polypeptide binding]; other site
979556001183	LBP interface [polypeptide binding]; other site
979556001184	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
979556001185	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
979556001186	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
979556001187	alpha subunit interaction interface [polypeptide binding]; other site
979556001188	Walker A motif; other site
979556001189	ATP binding site [chemical binding]; other site
979556001190	Walker B motif; other site
979556001191	inhibitor binding site; inhibition site
979556001192	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
979556001193	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
979556001194	core domain interface [polypeptide binding]; other site
979556001195	delta subunit interface [polypeptide binding]; other site
979556001196	epsilon subunit interface [polypeptide binding]; other site
979556001197	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
979556001198	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
979556001199	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
979556001200	beta subunit interaction interface [polypeptide binding]; other site
979556001201	Walker A motif; other site
979556001202	ATP binding site [chemical binding]; other site
979556001203	Walker B motif; other site
979556001204	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
979556001205	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
979556001206	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
979556001207	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
979556001208	ATP synthase subunit C; Region: ATP-synt_C; cl00466
979556001209	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
979556001210	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
979556001211	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
979556001212	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
979556001213	Mg++ binding site [ion binding]; other site
979556001214	putative catalytic motif [active]
979556001215	substrate binding site [chemical binding]; other site
979556001216	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
979556001217	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
979556001218	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
979556001219	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
979556001220	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
979556001221	dimer interface [polypeptide binding]; other site
979556001222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556001223	catalytic residue [active]
979556001224	serine O-acetyltransferase; Region: cysE; TIGR01172
979556001225	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
979556001226	trimer interface [polypeptide binding]; other site
979556001227	active site
979556001228	substrate binding site [chemical binding]; other site
979556001229	CoA binding site [chemical binding]; other site
979556001230	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
979556001231	Amidase; Region: Amidase; cl11426
979556001232	peptide chain release factor 1; Validated; Region: prfA; PRK00591
979556001233	This domain is found in peptide chain release factors; Region: PCRF; smart00937
979556001234	RF-1 domain; Region: RF-1; pfam00472
979556001235	transcription termination factor Rho; Provisional; Region: PRK12608
979556001236	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
979556001237	RNA binding site [nucleotide binding]; other site
979556001238	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
979556001239	multimer interface [polypeptide binding]; other site
979556001240	Walker A motif; other site
979556001241	ATP binding site [chemical binding]; other site
979556001242	Walker B motif; other site
979556001243	homoserine kinase; Provisional; Region: PRK01212
979556001244	threonine synthase; Reviewed; Region: PRK06721
979556001245	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
979556001246	homodimer interface [polypeptide binding]; other site
979556001247	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556001248	catalytic residue [active]
979556001249	homoserine dehydrogenase; Provisional; Region: PRK06349
979556001250	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
979556001251	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
979556001252	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
979556001253	diaminopimelate decarboxylase; Region: lysA; TIGR01048
979556001254	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
979556001255	active site
979556001256	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
979556001257	substrate binding site [chemical binding]; other site
979556001258	catalytic residues [active]
979556001259	dimer interface [polypeptide binding]; other site
979556001260	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556001261	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001262	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001263	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556001264	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001265	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556001266	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001267	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556001268	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001269	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001270	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556001271	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001272	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001273	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001274	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556001275	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556001276	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001277	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556001278	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
979556001279	MG2 domain; Region: A2M_N; pfam01835
979556001280	Peptidase M60-like family; Region: M60-like; pfam13402
979556001281	Protein of unknown function (DUF2993); Region: DUF2993; pfam11209
979556001282	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
979556001283	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
979556001284	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
979556001285	active site
979556001286	HIGH motif; other site
979556001287	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556001288	KMSK motif region; other site
979556001289	tRNA binding surface [nucleotide binding]; other site
979556001290	DALR anticodon binding domain; Region: DALR_1; smart00836
979556001291	anticodon binding site; other site
979556001292	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
979556001293	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
979556001294	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556001295	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
979556001296	active site
979556001297	ATP binding site [chemical binding]; other site
979556001298	substrate binding site [chemical binding]; other site
979556001299	activation loop (A-loop); other site
979556001300	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
979556001301	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
979556001302	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
979556001303	hypothetical protein; Reviewed; Region: PRK09588
979556001304	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556001305	MarR family; Region: MarR_2; pfam12802
979556001306	spore photoproduct lyase family protein; Region: lyase_spl_fam; TIGR03886
979556001307	Radical SAM superfamily; Region: Radical_SAM; pfam04055
979556001308	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
979556001309	N-terminal domain of the actinomycetal Nei2 and related DNA glycosylases; Region: AcNei2_N; cd08971
979556001310	putative DNA binding site [nucleotide binding]; other site
979556001311	catalytic residue [active]
979556001312	putative H2TH interface [polypeptide binding]; other site
979556001313	putative catalytic residues [active]
979556001314	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556001315	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
979556001316	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
979556001317	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556001318	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
979556001319	hydrophobic ligand binding site; other site
979556001320	GAF domain; Region: GAF; cl17456
979556001321	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556001322	dimer interface [polypeptide binding]; other site
979556001323	phosphorylation site [posttranslational modification]
979556001324	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556001325	ATP binding site [chemical binding]; other site
979556001326	Mg2+ binding site [ion binding]; other site
979556001327	G-X-G motif; other site
979556001328	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
979556001329	CAAX protease self-immunity; Region: Abi; pfam02517
979556001330	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556001331	S-adenosylmethionine binding site [chemical binding]; other site
979556001332	Protein of unknown function (DUF3097); Region: DUF3097; pfam11296
979556001333	Repair protein; Region: Repair_PSII; pfam04536
979556001334	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
979556001335	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
979556001336	active site
979556001337	Mn binding site [ion binding]; other site
979556001338	Siderophore-interacting protein; Region: SIP; pfam04954
979556001339	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
979556001340	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
979556001341	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
979556001342	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
979556001343	Uncharacterized conserved protein [Function unknown]; Region: COG2128
979556001344	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556001345	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
979556001346	catalytic site [active]
979556001347	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_6; cd08494
979556001348	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
979556001349	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556001350	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556001351	dimer interface [polypeptide binding]; other site
979556001352	conserved gate region; other site
979556001353	ABC-ATPase subunit interface; other site
979556001354	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
979556001355	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556001356	dimer interface [polypeptide binding]; other site
979556001357	conserved gate region; other site
979556001358	putative PBP binding loops; other site
979556001359	ABC-ATPase subunit interface; other site
979556001360	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556001361	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556001362	Walker A/P-loop; other site
979556001363	ATP binding site [chemical binding]; other site
979556001364	Q-loop/lid; other site
979556001365	ABC transporter signature motif; other site
979556001366	Walker B; other site
979556001367	D-loop; other site
979556001368	H-loop/switch region; other site
979556001369	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556001370	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556001371	Walker A/P-loop; other site
979556001372	ATP binding site [chemical binding]; other site
979556001373	Q-loop/lid; other site
979556001374	ABC transporter signature motif; other site
979556001375	Walker B; other site
979556001376	D-loop; other site
979556001377	H-loop/switch region; other site
979556001378	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556001379	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
979556001380	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
979556001381	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
979556001382	active site
979556001383	Zn binding site [ion binding]; other site
979556001384	HTH domain; Region: HTH_11; pfam08279
979556001385	WYL domain; Region: WYL; pfam13280
979556001386	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
979556001387	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
979556001388	ligand binding site [chemical binding]; other site
979556001389	active site
979556001390	UGI interface [polypeptide binding]; other site
979556001391	catalytic site [active]
979556001392	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
979556001393	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556001394	active site
979556001395	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
979556001396	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556001397	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
979556001398	NAD(P) binding site [chemical binding]; other site
979556001399	active site
979556001400	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK07812
979556001401	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
979556001402	homodimer interface [polypeptide binding]; other site
979556001403	substrate-cofactor binding pocket; other site
979556001404	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556001405	catalytic residue [active]
979556001406	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556001407	active site
979556001408	Domain of unknown function (DUF4259); Region: DUF4259; pfam14078
979556001409	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
979556001410	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
979556001411	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
979556001412	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556001413	putative substrate translocation pore; other site
979556001414	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
979556001415	ligand binding site [chemical binding]; other site
979556001416	FHA domain; Region: FHA; pfam00498
979556001417	phosphopeptide binding site; other site
979556001418	type VII secretion protein EccCa; Region: T7SS_EccC_a; TIGR03924
979556001419	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
979556001420	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
979556001421	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556001422	Walker A/P-loop; other site
979556001423	ATP binding site [chemical binding]; other site
979556001424	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556001425	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
979556001426	active site
979556001427	ATP binding site [chemical binding]; other site
979556001428	substrate binding site [chemical binding]; other site
979556001429	activation loop (A-loop); other site
979556001430	Domain of unknown function DUF77; Region: DUF77; pfam01910
979556001431	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
979556001432	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
979556001433	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
979556001434	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
979556001435	active site
979556001436	FMN binding site [chemical binding]; other site
979556001437	substrate binding site [chemical binding]; other site
979556001438	homotetramer interface [polypeptide binding]; other site
979556001439	catalytic residue [active]
979556001440	Domain of unknown function DUF21; Region: DUF21; pfam01595
979556001441	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
979556001442	FOG: CBS domain [General function prediction only]; Region: COG0517
979556001443	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
979556001444	Domain of unknown function DUF21; Region: DUF21; pfam01595
979556001445	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
979556001446	Transporter associated domain; Region: CorC_HlyC; smart01091
979556001447	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; cl01996
979556001448	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07807
979556001449	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
979556001450	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
979556001451	phosphate binding site [ion binding]; other site
979556001452	alpha-ketoglutarate decarboxylase; Reviewed; Region: kgd; PRK12270
979556001453	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
979556001454	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
979556001455	TPP-binding site [chemical binding]; other site
979556001456	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
979556001457	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
979556001458	hypothetical protein; Provisional; Region: PRK01346
979556001459	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
979556001460	mycothiol system anti-sigma-R factor; Region: antisig_RsrA; cl15806
979556001461	RNA polymerase sigma-70 factor, TIGR02947 family; Region: SigH_actino
979556001462	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556001463	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556001464	DNA binding residues [nucleotide binding]
979556001465	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
979556001466	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
979556001467	hinge; other site
979556001468	active site
979556001469	Predicted GTPases [General function prediction only]; Region: COG1162
979556001470	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
979556001471	GTPase/Zn-binding domain interface [polypeptide binding]; other site
979556001472	GTP/Mg2+ binding site [chemical binding]; other site
979556001473	G4 box; other site
979556001474	G5 box; other site
979556001475	G1 box; other site
979556001476	Switch I region; other site
979556001477	G2 box; other site
979556001478	G3 box; other site
979556001479	Switch II region; other site
979556001480	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
979556001481	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
979556001482	catalytic triad [active]
979556001483	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
979556001484	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
979556001485	Transcription factor WhiB; Region: Whib; pfam02467
979556001486	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
979556001487	PAS fold; Region: PAS_4; pfam08448
979556001488	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
979556001489	putative active site [active]
979556001490	heme pocket [chemical binding]; other site
979556001491	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
979556001492	Histidine kinase; Region: HisKA_2; pfam07568
979556001493	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556001494	ATP binding site [chemical binding]; other site
979556001495	Mg2+ binding site [ion binding]; other site
979556001496	G-X-G motif; other site
979556001497	Helix-turn-helix domain; Region: HTH_17; cl17695
979556001498	aminotransferase AlaT; Validated; Region: PRK09265
979556001499	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556001500	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556001501	homodimer interface [polypeptide binding]; other site
979556001502	catalytic residue [active]
979556001503	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
979556001504	DEAD/DEAH box helicase; Region: DEAD; pfam00270
979556001505	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
979556001506	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
979556001507	nucleotide binding region [chemical binding]; other site
979556001508	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
979556001509	30S subunit binding site; other site
979556001510	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
979556001511	active site
979556001512	lipoprotein LpqB; Provisional; Region: PRK13615
979556001513	Sporulation and spore germination; Region: Germane; pfam10646
979556001514	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556001515	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
979556001516	dimerization interface [polypeptide binding]; other site
979556001517	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556001518	dimer interface [polypeptide binding]; other site
979556001519	phosphorylation site [posttranslational modification]
979556001520	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556001521	ATP binding site [chemical binding]; other site
979556001522	Mg2+ binding site [ion binding]; other site
979556001523	G-X-G motif; other site
979556001524	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556001525	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556001526	active site
979556001527	phosphorylation site [posttranslational modification]
979556001528	intermolecular recognition site; other site
979556001529	dimerization interface [polypeptide binding]; other site
979556001530	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556001531	DNA binding site [nucleotide binding]
979556001532	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; cl01974
979556001533	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
979556001534	MoxR-like ATPases [General function prediction only]; Region: COG0714
979556001535	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556001536	Walker A motif; other site
979556001537	ATP binding site [chemical binding]; other site
979556001538	Walker B motif; other site
979556001539	arginine finger; other site
979556001540	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
979556001541	Protein of unknown function DUF58; Region: DUF58; pfam01882
979556001542	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09258
979556001543	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
979556001544	dimer interface [polypeptide binding]; other site
979556001545	active site
979556001546	CoA binding pocket [chemical binding]; other site
979556001547	haloalkane dehalogenase; Provisional; Region: PRK03592
979556001548	peptide synthase; Provisional; Region: PRK09274
979556001549	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556001550	acyl-activating enzyme (AAE) consensus motif; other site
979556001551	AMP binding site [chemical binding]; other site
979556001552	active site
979556001553	CoA binding site [chemical binding]; other site
979556001554	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
979556001555	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556001556	NAD(P) binding site [chemical binding]; other site
979556001557	active site
979556001558	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
979556001559	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
979556001560	dimer interface [polypeptide binding]; other site
979556001561	active site
979556001562	heme binding site [chemical binding]; other site
979556001563	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
979556001564	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
979556001565	metal binding site 2 [ion binding]; metal-binding site
979556001566	putative DNA binding helix; other site
979556001567	metal binding site 1 [ion binding]; metal-binding site
979556001568	dimer interface [polypeptide binding]; other site
979556001569	structural Zn2+ binding site [ion binding]; other site
979556001570	Integral membrane protein DUF95; Region: DUF95; pfam01944
979556001571	RDD family; Region: RDD; pfam06271
979556001572	Protein of unknown function (DUF3499); Region: DUF3499; pfam12005
979556001573	Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria; Region: MMP_TTHA0227_like_1; cd12954
979556001574	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
979556001575	Transcription factor WhiB; Region: Whib; pfam02467
979556001576	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
979556001577	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
979556001578	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
979556001579	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
979556001580	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
979556001581	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
979556001582	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556001583	active site
979556001584	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
979556001585	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_b; cd04185
979556001586	Probable Catalytic site; other site
979556001587	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
979556001588	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
979556001589	Walker A/P-loop; other site
979556001590	ATP binding site [chemical binding]; other site
979556001591	Q-loop/lid; other site
979556001592	ABC transporter signature motif; other site
979556001593	Walker B; other site
979556001594	D-loop; other site
979556001595	H-loop/switch region; other site
979556001596	ABC-2 type transporter; Region: ABC2_membrane; cl17235
979556001597	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
979556001598	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
979556001599	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556001600	UDP-galactopyranose mutase; Region: GLF; pfam03275
979556001601	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556001602	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
979556001603	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
979556001604	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
979556001605	Ligand binding site; other site
979556001606	Putative Catalytic site; other site
979556001607	DXD motif; other site
979556001608	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
979556001609	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556001610	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556001611	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
979556001612	Probable Catalytic site; other site
979556001613	metal-binding site
979556001614	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
979556001615	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
979556001616	active site
979556001617	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556001618	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
979556001619	NAD binding site [chemical binding]; other site
979556001620	putative substrate binding site 2 [chemical binding]; other site
979556001621	putative substrate binding site 1 [chemical binding]; other site
979556001622	active site
979556001623	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556001624	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556001625	NAD(P) binding site [chemical binding]; other site
979556001626	active site
979556001627	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
979556001628	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
979556001629	substrate binding site; other site
979556001630	tetramer interface; other site
979556001631	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
979556001632	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
979556001633	NAD binding site [chemical binding]; other site
979556001634	substrate binding site [chemical binding]; other site
979556001635	homodimer interface [polypeptide binding]; other site
979556001636	active site
979556001637	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
979556001638	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
979556001639	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
979556001640	NADP binding site [chemical binding]; other site
979556001641	active site
979556001642	putative substrate binding site [chemical binding]; other site
979556001643	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
979556001644	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
979556001645	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
979556001646	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
979556001647	Walker A/P-loop; other site
979556001648	ATP binding site [chemical binding]; other site
979556001649	Q-loop/lid; other site
979556001650	ABC transporter signature motif; other site
979556001651	Walker B; other site
979556001652	D-loop; other site
979556001653	H-loop/switch region; other site
979556001654	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
979556001655	putative carbohydrate binding site [chemical binding]; other site
979556001656	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556001657	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
979556001658	NAD(P) binding site [chemical binding]; other site
979556001659	active site
979556001660	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
979556001661	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556001662	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556001663	active site
979556001664	LGFP repeat; Region: LGFP; pfam08310
979556001665	LGFP repeat; Region: LGFP; pfam08310
979556001666	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
979556001667	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556001668	active site
979556001669	motif I; other site
979556001670	motif II; other site
979556001671	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
979556001672	active site
979556001673	dimer interface [polypeptide binding]; other site
979556001674	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
979556001675	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
979556001676	putative ribose interaction site [chemical binding]; other site
979556001677	putative ADP binding site [chemical binding]; other site
979556001678	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
979556001679	active site
979556001680	HIGH motif; other site
979556001681	nucleotide binding site [chemical binding]; other site
979556001682	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
979556001683	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556001684	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
979556001685	putative active site [active]
979556001686	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4641
979556001687	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
979556001688	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556001689	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556001690	Transcriptional regulator [Transcription]; Region: LytR; COG1316
979556001691	AIR carboxylase; Region: AIRC; pfam00731
979556001692	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
979556001693	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
979556001694	NAD binding site [chemical binding]; other site
979556001695	ATP-grasp domain; Region: ATP-grasp; pfam02222
979556001696	Bacterial PH domain; Region: DUF304; pfam03703
979556001697	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
979556001698	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
979556001699	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
979556001700	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
979556001701	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
979556001702	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
979556001703	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556001704	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556001705	Mg2+ binding site [ion binding]; other site
979556001706	G-X-G motif; other site
979556001707	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556001708	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556001709	DNA binding residues [nucleotide binding]
979556001710	TRAM domain; Region: TRAM; cl01282
979556001711	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
979556001712	Maf-like protein; Region: Maf; pfam02545
979556001713	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
979556001714	active site
979556001715	dimer interface [polypeptide binding]; other site
979556001716	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
979556001717	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
979556001718	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
979556001719	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
979556001720	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
979556001721	carboxyltransferase (CT) interaction site; other site
979556001722	biotinylation site [posttranslational modification]; other site
979556001723	flavoprotein disulfide reductase; Reviewed; Region: PRK07845
979556001724	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556001725	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556001726	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
979556001727	purine nucleoside phosphorylase; Provisional; Region: PRK08202
979556001728	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
979556001729	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
979556001730	active site
979556001731	substrate binding site [chemical binding]; other site
979556001732	metal binding site [ion binding]; metal-binding site
979556001733	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556001734	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556001735	DNA binding residues [nucleotide binding]
979556001736	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556001737	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556001738	active site
979556001739	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
979556001740	exosortase/archaeosortase family protein; Region: exo_archaeo; TIGR04178
979556001741	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
979556001742	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
979556001743	active site
979556001744	homodimer interface [polypeptide binding]; other site
979556001745	PRD domain; Region: PRD; pfam00874
979556001746	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
979556001747	active site
979556001748	P-loop; other site
979556001749	phosphorylation site [posttranslational modification]
979556001750	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
979556001751	active site
979556001752	phosphorylation site [posttranslational modification]
979556001753	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
979556001754	active site
979556001755	P-loop; other site
979556001756	phosphorylation site [posttranslational modification]
979556001757	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
979556001758	dimerization domain swap beta strand [polypeptide binding]; other site
979556001759	regulatory protein interface [polypeptide binding]; other site
979556001760	active site
979556001761	regulatory phosphorylation site [posttranslational modification]; other site
979556001762	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
979556001763	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
979556001764	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
979556001765	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
979556001766	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
979556001767	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
979556001768	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
979556001769	active site
979556001770	P-loop; other site
979556001771	phosphorylation site [posttranslational modification]
979556001772	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
979556001773	active site
979556001774	phosphorylation site [posttranslational modification]
979556001775	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
979556001776	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
979556001777	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
979556001778	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
979556001779	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
979556001780	putative active site [active]
979556001781	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
979556001782	adenosine deaminase; Provisional; Region: PRK09358
979556001783	active site
979556001784	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
979556001785	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
979556001786	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
979556001787	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
979556001788	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
979556001789	active site
979556001790	catalytic motif [active]
979556001791	Zn binding site [ion binding]; other site
979556001792	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556001793	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
979556001794	TM-ABC transporter signature motif; other site
979556001795	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556001796	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
979556001797	TM-ABC transporter signature motif; other site
979556001798	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
979556001799	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556001800	Walker A/P-loop; other site
979556001801	ATP binding site [chemical binding]; other site
979556001802	Q-loop/lid; other site
979556001803	ABC transporter signature motif; other site
979556001804	Walker B; other site
979556001805	D-loop; other site
979556001806	H-loop/switch region; other site
979556001807	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556001808	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556001809	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
979556001810	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
979556001811	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
979556001812	Substrate binding site; other site
979556001813	Cupin domain; Region: Cupin_2; cl17218
979556001814	Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase C (SdhC)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this subfamily reduce low potential...; Region: SQR_TypeA_SdhC_like; cd03501
979556001815	putative Iron-sulfur protein interface [polypeptide binding]; other site
979556001816	putative proximal heme binding site [chemical binding]; other site
979556001817	putative SdhD-like interface [polypeptide binding]; other site
979556001818	putative distal heme binding site [chemical binding]; other site
979556001819	Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase D (SdhD)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this subfamily reduce low potential...; Region: SQR_TypeA_SdhD_like; cd03500
979556001820	putative Iron-sulfur protein interface [polypeptide binding]; other site
979556001821	putative proximal heme binding site [chemical binding]; other site
979556001822	putative SdhC-like subunit interface [polypeptide binding]; other site
979556001823	putative distal heme binding site [chemical binding]; other site
979556001824	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08205
979556001825	L-aspartate oxidase; Provisional; Region: PRK06175
979556001826	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
979556001827	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
979556001828	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
979556001829	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
979556001830	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
979556001831	putative active site [active]
979556001832	putative catalytic site [active]
979556001833	putative DNA binding site [nucleotide binding]; other site
979556001834	putative phosphate binding site [ion binding]; other site
979556001835	metal binding site A [ion binding]; metal-binding site
979556001836	putative AP binding site [nucleotide binding]; other site
979556001837	putative metal binding site B [ion binding]; other site
979556001838	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
979556001839	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
979556001840	active site
979556001841	HIGH motif; other site
979556001842	dimer interface [polypeptide binding]; other site
979556001843	KMSKS motif; other site
979556001844	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
979556001845	Uncharacterized bacterial subgroup of the N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei  (endonuclease VIII) base-excision repair DNA glycosylases; Region: BaFpgNei_N_1; cd08973
979556001846	putative DNA binding site [nucleotide binding]; other site
979556001847	catalytic residue [active]
979556001848	putative H2TH interface [polypeptide binding]; other site
979556001849	putative catalytic residues [active]
979556001850	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556001851	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
979556001852	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
979556001853	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
979556001854	catalytic motif [active]
979556001855	Zn binding site [ion binding]; other site
979556001856	RibD C-terminal domain; Region: RibD_C; cl17279
979556001857	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
979556001858	Lumazine binding domain; Region: Lum_binding; pfam00677
979556001859	Lumazine binding domain; Region: Lum_binding; pfam00677
979556001860	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
979556001861	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
979556001862	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
979556001863	dimerization interface [polypeptide binding]; other site
979556001864	active site
979556001865	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
979556001866	homopentamer interface [polypeptide binding]; other site
979556001867	active site
979556001868	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556001869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556001870	putative substrate translocation pore; other site
979556001871	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556001872	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556001873	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
979556001874	Walker A/P-loop; other site
979556001875	ATP binding site [chemical binding]; other site
979556001876	Q-loop/lid; other site
979556001877	ABC transporter signature motif; other site
979556001878	Walker B; other site
979556001879	D-loop; other site
979556001880	H-loop/switch region; other site
979556001881	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
979556001882	active site
979556001883	substrate-binding site [chemical binding]; other site
979556001884	metal-binding site [ion binding]
979556001885	GTP binding site [chemical binding]; other site
979556001886	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556001887	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556001888	non-specific DNA binding site [nucleotide binding]; other site
979556001889	salt bridge; other site
979556001890	sequence-specific DNA binding site [nucleotide binding]; other site
979556001891	Predicted transcriptional regulator [General function prediction only]; Region: COG3800
979556001892	Domain of unknown function (DUF955); Region: DUF955; pfam06114
979556001893	NMT1/THI5 like; Region: NMT1; pfam09084
979556001894	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
979556001895	membrane-bound complex binding site; other site
979556001896	hinge residues; other site
979556001897	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
979556001898	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
979556001899	conserved cys residue [active]
979556001900	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556001901	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
979556001902	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
979556001903	Walker A/P-loop; other site
979556001904	ATP binding site [chemical binding]; other site
979556001905	Q-loop/lid; other site
979556001906	ABC transporter signature motif; other site
979556001907	Walker B; other site
979556001908	D-loop; other site
979556001909	H-loop/switch region; other site
979556001910	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
979556001911	GTP cyclohydrolase I; Provisional; Region: PLN03044
979556001912	active site
979556001913	Creatinine amidohydrolase; Region: Creatininase; pfam02633
979556001914	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556001915	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556001916	DNA binding site [nucleotide binding]
979556001917	domain linker motif; other site
979556001918	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556001919	dimerization interface [polypeptide binding]; other site
979556001920	ligand binding site [chemical binding]; other site
979556001921	succinic semialdehyde dehydrogenase; Region: PLN02278
979556001922	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
979556001923	tetramerization interface [polypeptide binding]; other site
979556001924	NAD(P) binding site [chemical binding]; other site
979556001925	catalytic residues [active]
979556001926	phenol 2-monooxygenase; Provisional; Region: PRK08294
979556001927	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556001928	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556001929	FAD-dependent Phenol hydoxylase (PHOX) family, C-terminal TRX-fold domain; composed of proteins similar to PHOX from the aerobic topsoil yeast Trichosporon cutaneum. PHOX is a flavoprotein monooxygenase that catalyzes the hydroxylation of phenol and...; Region: PHOX_C; cd02979
979556001930	dimer interface [polypeptide binding]; other site
979556001931	Transcriptional regulator [Transcription]; Region: IclR; COG1414
979556001932	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
979556001933	Double zinc ribbon; Region: DZR; pfam12773
979556001934	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
979556001935	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556001936	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556001937	MarR family; Region: MarR_2; pfam12802
979556001938	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556001939	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556001940	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556001941	nucleotide binding site [chemical binding]; other site
979556001942	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
979556001943	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556001944	Walker A/P-loop; other site
979556001945	ATP binding site [chemical binding]; other site
979556001946	Q-loop/lid; other site
979556001947	ABC transporter signature motif; other site
979556001948	Walker B; other site
979556001949	D-loop; other site
979556001950	H-loop/switch region; other site
979556001951	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
979556001952	ligand binding site [chemical binding]; other site
979556001953	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
979556001954	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556001955	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556001956	TM-ABC transporter signature motif; other site
979556001957	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
979556001958	active site
979556001959	catalytic triad [active]
979556001960	oxyanion hole [active]
979556001961	tyramine oxidase; Provisional; Region: tynA; PRK11504
979556001962	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
979556001963	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
979556001964	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
979556001965	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556001966	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556001967	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
979556001968	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
979556001969	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556001970	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556001971	classical (c) SDRs; Region: SDR_c; cd05233
979556001972	NAD(P) binding site [chemical binding]; other site
979556001973	active site
979556001974	classical (c) SDRs; Region: SDR_c; cd05233
979556001975	NAD(P) binding site [chemical binding]; other site
979556001976	active site
979556001977	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556001978	Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703
979556001979	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556001980	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556001981	TM-ABC transporter signature motif; other site
979556001982	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556001983	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556001984	Walker A/P-loop; other site
979556001985	ATP binding site [chemical binding]; other site
979556001986	Q-loop/lid; other site
979556001987	ABC transporter signature motif; other site
979556001988	Walker B; other site
979556001989	D-loop; other site
979556001990	H-loop/switch region; other site
979556001991	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556001992	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
979556001993	ligand binding site [chemical binding]; other site
979556001994	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
979556001995	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
979556001996	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
979556001997	active site
979556001998	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
979556001999	Streptomyces aureofaciens putative aldehyde dehydrogenase AldA (AAD23400)-like; Region: ALDH_AldA-AAD23400; cd07106
979556002000	NAD(P) binding site [chemical binding]; other site
979556002001	catalytic residues [active]
979556002002	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
979556002003	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
979556002004	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
979556002005	PYR/PP interface [polypeptide binding]; other site
979556002006	dimer interface [polypeptide binding]; other site
979556002007	TPP binding site [chemical binding]; other site
979556002008	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
979556002009	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
979556002010	TPP-binding site [chemical binding]; other site
979556002011	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556002012	Coenzyme A binding pocket [chemical binding]; other site
979556002013	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556002014	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
979556002015	Transcriptional regulators [Transcription]; Region: GntR; COG1802
979556002016	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556002017	DNA-binding site [nucleotide binding]; DNA binding site
979556002018	FCD domain; Region: FCD; pfam07729
979556002019	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
979556002020	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
979556002021	NAD binding site [chemical binding]; other site
979556002022	catalytic residues [active]
979556002023	3,4-dihydroxyphenylacetate 2,3-dioxygenase; Region: HpaD; TIGR02295
979556002024	N-terminal domain of 3,4-dihydroxyphenylacetate 2,3-dioxygenase (HPCD); belongs to the type I class II family of extradiol dioxygenases; Region: HPCD_N_class_II; cd07266
979556002025	tetramer interface [polypeptide binding]; other site
979556002026	C-terminal domain of 3,4-dihydroxyphenylacetate 2,3-dioxygenase (HPCD), which catalyses the second step in the degradation of 4-hydroxyphenylacetate to succinate and pyruvate; belongs to the type I class II family of extradiol dioxygenases; Region: HPCD_C_class_II; cd07256
979556002027	tetramer interface [polypeptide binding]; other site
979556002028	active site
979556002029	metal binding site [ion binding]; metal-binding site
979556002030	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
979556002031	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism]; Region: HpcH; COG3836
979556002032	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14193
979556002033	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
979556002034	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
979556002035	homodimer interface [polypeptide binding]; other site
979556002036	NADP binding site [chemical binding]; other site
979556002037	substrate binding site [chemical binding]; other site
979556002038	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
979556002039	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
979556002040	dimer interface [polypeptide binding]; other site
979556002041	active site
979556002042	glycine-pyridoxal phosphate binding site [chemical binding]; other site
979556002043	folate binding site [chemical binding]; other site
979556002044	Protein of unknown function (DUF2568); Region: DUF2568; pfam10823
979556002045	FAD binding domain; Region: FAD_binding_4; pfam01565
979556002046	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
979556002047	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
979556002048	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
979556002049	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
979556002050	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
979556002051	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
979556002052	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556002053	Coenzyme A binding pocket [chemical binding]; other site
979556002054	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
979556002055	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
979556002056	putative active site [active]
979556002057	Helix-turn-helix domain; Region: HTH_38; pfam13936
979556002058	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
979556002059	Homeodomain-like domain; Region: HTH_32; pfam13565
979556002060	Integrase core domain; Region: rve; pfam00665
979556002061	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556002062	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556002063	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556002064	Walker A/P-loop; other site
979556002065	ATP binding site [chemical binding]; other site
979556002066	Q-loop/lid; other site
979556002067	ABC transporter signature motif; other site
979556002068	Walker B; other site
979556002069	D-loop; other site
979556002070	H-loop/switch region; other site
979556002071	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556002072	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556002073	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556002074	Walker A/P-loop; other site
979556002075	ATP binding site [chemical binding]; other site
979556002076	Q-loop/lid; other site
979556002077	ABC transporter signature motif; other site
979556002078	Walker B; other site
979556002079	D-loop; other site
979556002080	H-loop/switch region; other site
979556002081	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
979556002082	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
979556002083	DNA binding site [nucleotide binding]
979556002084	active site
979556002085	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
979556002086	Helix-turn-helix domain; Region: HTH_18; pfam12833
979556002087	AlkA N-terminal domain; Region: AlkA_N; pfam06029
979556002088	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
979556002089	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
979556002090	minor groove reading motif; other site
979556002091	helix-hairpin-helix signature motif; other site
979556002092	substrate binding pocket [chemical binding]; other site
979556002093	active site
979556002094	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
979556002095	active site
979556002096	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556002097	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002098	dimer interface [polypeptide binding]; other site
979556002099	conserved gate region; other site
979556002100	putative PBP binding loops; other site
979556002101	ABC-ATPase subunit interface; other site
979556002102	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
979556002103	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002104	ABC-ATPase subunit interface; other site
979556002105	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556002106	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556002107	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556002108	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556002109	DNA binding site [nucleotide binding]
979556002110	domain linker motif; other site
979556002111	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556002112	ligand binding site [chemical binding]; other site
979556002113	dimerization interface [polypeptide binding]; other site
979556002114	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
979556002115	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
979556002116	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556002117	NAD binding site [chemical binding]; other site
979556002118	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
979556002119	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
979556002120	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
979556002121	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
979556002122	purine monophosphate binding site [chemical binding]; other site
979556002123	dimer interface [polypeptide binding]; other site
979556002124	putative catalytic residues [active]
979556002125	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
979556002126	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
979556002127	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
979556002128	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
979556002129	active site
979556002130	substrate binding site [chemical binding]; other site
979556002131	cosubstrate binding site; other site
979556002132	catalytic site [active]
979556002133	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
979556002134	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
979556002135	putative active site [active]
979556002136	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_C; cd03414
979556002137	putative active site [active]
979556002138	bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Validated; Region: PRK07239
979556002139	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
979556002140	active site
979556002141	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
979556002142	DNA binding site [nucleotide binding]
979556002143	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
979556002144	nitrite reductase subunit NirD; Provisional; Region: PRK14989
979556002145	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556002146	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
979556002147	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
979556002148	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
979556002149	Domain of unknown function (DUF385); Region: DUF385; pfam04075
979556002150	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
979556002151	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
979556002152	CoA binding domain; Region: CoA_binding; smart00881
979556002153	CoA-ligase; Region: Ligase_CoA; pfam00549
979556002154	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
979556002155	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
979556002156	CoA-ligase; Region: Ligase_CoA; pfam00549
979556002157	Zinc carboxypeptidase; Region: Peptidase_M14; pfam00246
979556002158	active site
979556002159	Zn binding site [ion binding]; other site
979556002160	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556002161	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556002162	active site
979556002163	phosphorylation site [posttranslational modification]
979556002164	intermolecular recognition site; other site
979556002165	dimerization interface [polypeptide binding]; other site
979556002166	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556002167	DNA binding residues [nucleotide binding]
979556002168	dimerization interface [polypeptide binding]; other site
979556002169	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556002170	Histidine kinase; Region: HisKA_3; pfam07730
979556002171	Domain of unknown function (DUF4375); Region: DUF4375; pfam14300
979556002172	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
979556002173	nucleoside/Zn binding site; other site
979556002174	dimer interface [polypeptide binding]; other site
979556002175	catalytic motif [active]
979556002176	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
979556002177	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556002178	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
979556002179	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
979556002180	active site residue [active]
979556002181	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1937
979556002182	putative homotetramer interface [polypeptide binding]; other site
979556002183	putative homodimer interface [polypeptide binding]; other site
979556002184	putative allosteric switch controlling residues; other site
979556002185	putative metal binding site [ion binding]; other site
979556002186	putative homodimer-homodimer interface [polypeptide binding]; other site
979556002187	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
979556002188	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
979556002189	dimerization interface [polypeptide binding]; other site
979556002190	Phospholipid methyltransferase; Region: PEMT; cl17370
979556002191	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
979556002192	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556002193	Walker A/P-loop; other site
979556002194	ATP binding site [chemical binding]; other site
979556002195	Q-loop/lid; other site
979556002196	ABC transporter signature motif; other site
979556002197	Walker B; other site
979556002198	D-loop; other site
979556002199	H-loop/switch region; other site
979556002200	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
979556002201	active site
979556002202	putative substrate binding region [chemical binding]; other site
979556002203	Predicted flavoprotein [General function prediction only]; Region: COG0431
979556002204	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
979556002205	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556002206	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556002207	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
979556002208	homotrimer interaction site [polypeptide binding]; other site
979556002209	putative active site [active]
979556002210	Epoxide hydrolase N terminus; Region: EHN; pfam06441
979556002211	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556002212	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
979556002213	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
979556002214	metal binding site [ion binding]; metal-binding site
979556002215	Domain of unknown function (DUF955); Region: DUF955; cl01076
979556002216	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
979556002217	ADP-ribose binding site [chemical binding]; other site
979556002218	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
979556002219	active site
979556002220	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556002221	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
979556002222	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
979556002223	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
979556002224	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
979556002225	[4Fe-4S] binding site [ion binding]; other site
979556002226	molybdopterin cofactor binding site; other site
979556002227	This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex  and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508
979556002228	molybdopterin cofactor binding site; other site
979556002229	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
979556002230	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556002231	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
979556002232	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
979556002233	Peptidase domain in the S53 family; Region: Peptidases_S53_like; cd05562
979556002234	putative active site [active]
979556002235	putative catalytic triad [active]
979556002236	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
979556002237	catalytic residues [active]
979556002238	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
979556002239	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556002240	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
979556002241	putative deacylase active site [active]
979556002242	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556002243	acyl-coenzyme A oxidase; Region: PLN02526
979556002244	active site
979556002245	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
979556002246	Domain of unknown function DUF20; Region: UPF0118; pfam01594
979556002247	Adenylation domain of Mycobacterium tuberculosis LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigC; cd07905
979556002248	ATP-dependent DNA ligase; Reviewed; Region: ligC; PRK08224
979556002249	active site
979556002250	DNA binding site [nucleotide binding]
979556002251	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigC is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigC; cd07970
979556002252	DNA binding site [nucleotide binding]
979556002253	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
979556002254	nucleotide binding site [chemical binding]; other site
979556002255	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
979556002256	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
979556002257	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
979556002258	Part of AAA domain; Region: AAA_19; pfam13245
979556002259	Family description; Region: UvrD_C_2; pfam13538
979556002260	hypothetical protein; Provisional; Region: PRK11770
979556002261	Domain of unknown function (DUF307); Region: DUF307; pfam03733
979556002262	Domain of unknown function (DUF307); Region: DUF307; pfam03733
979556002263	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556002264	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
979556002265	active site
979556002266	MarR family; Region: MarR_2; cl17246
979556002267	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556002268	Transcriptional regulators [Transcription]; Region: GntR; COG1802
979556002269	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
979556002270	DNA-binding site [nucleotide binding]; DNA binding site
979556002271	FCD domain; Region: FCD; cl11656
979556002272	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556002273	dimerization interface [polypeptide binding]; other site
979556002274	putative DNA binding site [nucleotide binding]; other site
979556002275	putative Zn2+ binding site [ion binding]; other site
979556002276	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556002277	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556002278	NAD(P) binding site [chemical binding]; other site
979556002279	active site
979556002280	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556002281	RNA binding surface [nucleotide binding]; other site
979556002282	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556002283	dimerization interface [polypeptide binding]; other site
979556002284	putative DNA binding site [nucleotide binding]; other site
979556002285	putative Zn2+ binding site [ion binding]; other site
979556002286	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
979556002287	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
979556002288	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
979556002289	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556002290	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556002291	Walker A/P-loop; other site
979556002292	ATP binding site [chemical binding]; other site
979556002293	Q-loop/lid; other site
979556002294	ABC transporter signature motif; other site
979556002295	Walker B; other site
979556002296	D-loop; other site
979556002297	H-loop/switch region; other site
979556002298	Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]; Region: COG3380
979556002299	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556002300	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
979556002301	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
979556002302	active site
979556002303	catalytic site [active]
979556002304	Bax inhibitor 1 like; Region: BaxI_1; cl17691
979556002305	LigD_Pol_like_2: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD, subgroup 2. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required...; Region: LigD_Pol_like_2; cd04865
979556002306	nucleotide binding site [chemical binding]; other site
979556002307	WHG domain; Region: WHG; pfam13305
979556002308	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
979556002309	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556002310	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002311	GMP synthase; Reviewed; Region: guaA; PRK00074
979556002312	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
979556002313	AMP/PPi binding site [chemical binding]; other site
979556002314	candidate oxyanion hole; other site
979556002315	catalytic triad [active]
979556002316	potential glutamine specificity residues [chemical binding]; other site
979556002317	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
979556002318	ATP Binding subdomain [chemical binding]; other site
979556002319	Ligand Binding sites [chemical binding]; other site
979556002320	Dimerization subdomain; other site
979556002321	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
979556002322	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cl01321
979556002323	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK08649
979556002324	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
979556002325	active site
979556002326	Protein of unknown function (DUF1211); Region: DUF1211; pfam06736
979556002327	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
979556002328	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556002329	Walker A/P-loop; other site
979556002330	ATP binding site [chemical binding]; other site
979556002331	Q-loop/lid; other site
979556002332	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556002333	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556002334	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
979556002335	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
979556002336	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
979556002337	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
979556002338	active site
979556002339	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
979556002340	TM-ABC transporter signature motif; other site
979556002341	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
979556002342	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
979556002343	TM-ABC transporter signature motif; other site
979556002344	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
979556002345	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
979556002346	Walker A/P-loop; other site
979556002347	ATP binding site [chemical binding]; other site
979556002348	Q-loop/lid; other site
979556002349	ABC transporter signature motif; other site
979556002350	Walker B; other site
979556002351	D-loop; other site
979556002352	H-loop/switch region; other site
979556002353	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
979556002354	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
979556002355	Walker A/P-loop; other site
979556002356	ATP binding site [chemical binding]; other site
979556002357	Q-loop/lid; other site
979556002358	ABC transporter signature motif; other site
979556002359	Walker B; other site
979556002360	D-loop; other site
979556002361	H-loop/switch region; other site
979556002362	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
979556002363	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556002364	Predicted permeases [General function prediction only]; Region: RarD; COG2962
979556002365	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
979556002366	oligomerisation interface [polypeptide binding]; other site
979556002367	mobile loop; other site
979556002368	roof hairpin; other site
979556002369	UGMP family protein; Validated; Region: PRK09604
979556002370	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
979556002371	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
979556002372	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
979556002373	Glycoprotease family; Region: Peptidase_M22; pfam00814
979556002374	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556002375	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556002376	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556002377	dimer interface [polypeptide binding]; other site
979556002378	phosphorylation site [posttranslational modification]
979556002379	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556002380	ATP binding site [chemical binding]; other site
979556002381	G-X-G motif; other site
979556002382	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556002383	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556002384	active site
979556002385	phosphorylation site [posttranslational modification]
979556002386	intermolecular recognition site; other site
979556002387	dimerization interface [polypeptide binding]; other site
979556002388	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556002389	DNA binding site [nucleotide binding]
979556002390	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
979556002391	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
979556002392	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
979556002393	ligand binding site [chemical binding]; other site
979556002394	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
979556002395	alanine racemase; Reviewed; Region: alr; PRK00053
979556002396	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
979556002397	active site
979556002398	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
979556002399	dimer interface [polypeptide binding]; other site
979556002400	substrate binding site [chemical binding]; other site
979556002401	catalytic residues [active]
979556002402	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
979556002403	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
979556002404	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
979556002405	glutaminase active site [active]
979556002406	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
979556002407	dimer interface [polypeptide binding]; other site
979556002408	active site
979556002409	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
979556002410	dimer interface [polypeptide binding]; other site
979556002411	active site
979556002412	pantothenate kinase; Provisional; Region: PRK05439
979556002413	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
979556002414	ATP-binding site [chemical binding]; other site
979556002415	CoA-binding site [chemical binding]; other site
979556002416	Mg2+-binding site [ion binding]; other site
979556002417	exopolyphosphatase; Region: exo_poly_only; TIGR03706
979556002418	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
979556002419	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14318
979556002420	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
979556002421	active site
979556002422	substrate binding site [chemical binding]; other site
979556002423	metal binding site [ion binding]; metal-binding site
979556002424	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
979556002425	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
979556002426	23S rRNA interface [nucleotide binding]; other site
979556002427	L3 interface [polypeptide binding]; other site
979556002428	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556002429	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556002430	TAP-like protein; Region: Abhydrolase_4; pfam08386
979556002431	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556002432	MarR family; Region: MarR; pfam01047
979556002433	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
979556002434	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556002435	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556002436	active site
979556002437	phosphorylation site [posttranslational modification]
979556002438	intermolecular recognition site; other site
979556002439	dimerization interface [polypeptide binding]; other site
979556002440	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556002441	DNA binding residues [nucleotide binding]
979556002442	dimerization interface [polypeptide binding]; other site
979556002443	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556002444	OPT oligopeptide transporter protein; Region: OPT; cl14607
979556002445	Histidine kinase; Region: HisKA_3; pfam07730
979556002446	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
979556002447	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
979556002448	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
979556002449	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
979556002450	Bacterial sugar transferase; Region: Bac_transf; pfam02397
979556002451	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
979556002452	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
979556002453	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
979556002454	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
979556002455	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
979556002456	ABC1 family; Region: ABC1; pfam03109
979556002457	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
979556002458	active site
979556002459	ATP binding site [chemical binding]; other site
979556002460	Low molecular weight phosphatase family; Region: LMWPc; cl00105
979556002461	active site
979556002462	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556002463	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556002464	non-specific DNA binding site [nucleotide binding]; other site
979556002465	salt bridge; other site
979556002466	sequence-specific DNA binding site [nucleotide binding]; other site
979556002467	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
979556002468	Bacterial sugar transferase; Region: Bac_transf; pfam02397
979556002469	Chain length determinant protein; Region: Wzz; pfam02706
979556002470	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
979556002471	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556002472	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
979556002473	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556002474	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556002475	DNA binding residues [nucleotide binding]
979556002476	dimerization interface [polypeptide binding]; other site
979556002477	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556002478	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556002479	Walker A/P-loop; other site
979556002480	ATP binding site [chemical binding]; other site
979556002481	Q-loop/lid; other site
979556002482	ABC transporter signature motif; other site
979556002483	Walker B; other site
979556002484	D-loop; other site
979556002485	H-loop/switch region; other site
979556002486	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
979556002487	FtsX-like permease family; Region: FtsX; pfam02687
979556002488	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556002489	MarR family; Region: MarR; pfam01047
979556002490	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
979556002491	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
979556002492	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
979556002493	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556002494	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556002495	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002496	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
979556002497	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
979556002498	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556002499	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556002500	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
979556002501	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556002502	F420-dependent oxidoreductase, G6PDH family; Region: F420_G6P_family; TIGR03557
979556002503	Right handed beta helix region; Region: Beta_helix; pfam13229
979556002504	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556002505	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556002506	active site
979556002507	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
979556002508	PPOX class probable F420-dependent enzyme; Region: Rv1155_F420; TIGR03618
979556002509	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
979556002510	Predicted membrane protein [Function unknown]; Region: COG4270
979556002511	RNA polymerase sigma factor SigK; Reviewed; Region: PRK09646
979556002512	MarR family; Region: MarR; pfam01047
979556002513	Glycosyl hydrolases family 6; Region: Glyco_hydro_6; pfam01341
979556002514	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556002515	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556002516	active site
979556002517	phosphorylation site [posttranslational modification]
979556002518	intermolecular recognition site; other site
979556002519	dimerization interface [polypeptide binding]; other site
979556002520	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556002521	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556002522	DNA binding site [nucleotide binding]
979556002523	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556002524	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
979556002525	DXD motif; other site
979556002526	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
979556002527	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
979556002528	putative active site [active]
979556002529	heme pocket [chemical binding]; other site
979556002530	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556002531	dimer interface [polypeptide binding]; other site
979556002532	phosphorylation site [posttranslational modification]
979556002533	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556002534	ATP binding site [chemical binding]; other site
979556002535	Mg2+ binding site [ion binding]; other site
979556002536	G-X-G motif; other site
979556002537	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
979556002538	I-site; other site
979556002539	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
979556002540	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
979556002541	putative catalytic site [active]
979556002542	putative metal binding site [ion binding]; other site
979556002543	putative phosphate binding site [ion binding]; other site
979556002544	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
979556002545	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
979556002546	dimerization interface 3.5A [polypeptide binding]; other site
979556002547	active site
979556002548	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
979556002549	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
979556002550	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
979556002551	alphaNTD homodimer interface [polypeptide binding]; other site
979556002552	alphaNTD - beta interaction site [polypeptide binding]; other site
979556002553	alphaNTD - beta' interaction site [polypeptide binding]; other site
979556002554	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
979556002555	30S ribosomal protein S11; Validated; Region: PRK05309
979556002556	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
979556002557	30S ribosomal protein S13; Region: bact_S13; TIGR03631
979556002558	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
979556002559	rRNA binding site [nucleotide binding]; other site
979556002560	predicted 30S ribosome binding site; other site
979556002561	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
979556002562	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
979556002563	catalytic residues [active]
979556002564	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
979556002565	active site
979556002566	adenylate kinase; Reviewed; Region: adk; PRK00279
979556002567	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
979556002568	AMP-binding site [chemical binding]; other site
979556002569	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
979556002570	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
979556002571	SecY translocase; Region: SecY; pfam00344
979556002572	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
979556002573	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
979556002574	23S rRNA binding site [nucleotide binding]; other site
979556002575	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
979556002576	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
979556002577	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
979556002578	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
979556002579	5S rRNA interface [nucleotide binding]; other site
979556002580	L27 interface [polypeptide binding]; other site
979556002581	23S rRNA interface [nucleotide binding]; other site
979556002582	L5 interface [polypeptide binding]; other site
979556002583	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
979556002584	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
979556002585	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
979556002586	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
979556002587	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
979556002588	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
979556002589	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
979556002590	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
979556002591	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
979556002592	RNA binding site [nucleotide binding]; other site
979556002593	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
979556002594	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
979556002595	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
979556002596	23S rRNA interface [nucleotide binding]; other site
979556002597	putative translocon interaction site; other site
979556002598	signal recognition particle (SRP54) interaction site; other site
979556002599	L23 interface [polypeptide binding]; other site
979556002600	trigger factor interaction site; other site
979556002601	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
979556002602	23S rRNA interface [nucleotide binding]; other site
979556002603	5S rRNA interface [nucleotide binding]; other site
979556002604	putative antibiotic binding site [chemical binding]; other site
979556002605	L25 interface [polypeptide binding]; other site
979556002606	L27 interface [polypeptide binding]; other site
979556002607	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
979556002608	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
979556002609	G-X-X-G motif; other site
979556002610	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
979556002611	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
979556002612	protein-rRNA interface [nucleotide binding]; other site
979556002613	putative translocon binding site; other site
979556002614	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
979556002615	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
979556002616	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
979556002617	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
979556002618	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
979556002619	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
979556002620	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
979556002621	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
979556002622	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
979556002623	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
979556002624	Chain length determinant protein; Region: Wzz; cl15801
979556002625	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
979556002626	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556002627	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
979556002628	Low molecular weight phosphatase family; Region: LMWPc; cl00105
979556002629	active site
979556002630	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556002631	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
979556002632	NAD(P) binding site [chemical binding]; other site
979556002633	active site
979556002634	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
979556002635	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
979556002636	NADP-binding site; other site
979556002637	homotetramer interface [polypeptide binding]; other site
979556002638	substrate binding site [chemical binding]; other site
979556002639	homodimer interface [polypeptide binding]; other site
979556002640	active site
979556002641	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
979556002642	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002643	putative ADP-binding pocket [chemical binding]; other site
979556002644	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
979556002645	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002646	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002647	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
979556002648	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556002649	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
979556002650	active site
979556002651	Acyltransferase family; Region: Acyl_transf_3; pfam01757
979556002652	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
979556002653	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
979556002654	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
979556002655	VanZ like family; Region: VanZ; cl01971
979556002656	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
979556002657	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556002658	active site
979556002659	Predicted membrane protein [Function unknown]; Region: COG2246
979556002660	GtrA-like protein; Region: GtrA; pfam04138
979556002661	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
979556002662	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002663	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556002664	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
979556002665	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
979556002666	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
979556002667	trimer interface [polypeptide binding]; other site
979556002668	active site
979556002669	substrate binding site [chemical binding]; other site
979556002670	CoA binding site [chemical binding]; other site
979556002671	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556002672	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556002673	elongation factor Tu; Reviewed; Region: PRK00049
979556002674	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
979556002675	G1 box; other site
979556002676	GEF interaction site [polypeptide binding]; other site
979556002677	GTP/Mg2+ binding site [chemical binding]; other site
979556002678	Switch I region; other site
979556002679	G2 box; other site
979556002680	G3 box; other site
979556002681	Switch II region; other site
979556002682	G4 box; other site
979556002683	G5 box; other site
979556002684	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
979556002685	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
979556002686	Antibiotic Binding Site [chemical binding]; other site
979556002687	elongation factor G; Reviewed; Region: PRK00007
979556002688	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
979556002689	G1 box; other site
979556002690	putative GEF interaction site [polypeptide binding]; other site
979556002691	GTP/Mg2+ binding site [chemical binding]; other site
979556002692	Switch I region; other site
979556002693	G2 box; other site
979556002694	G3 box; other site
979556002695	Switch II region; other site
979556002696	G4 box; other site
979556002697	G5 box; other site
979556002698	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
979556002699	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
979556002700	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
979556002701	30S ribosomal protein S7; Validated; Region: PRK05302
979556002702	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
979556002703	S17 interaction site [polypeptide binding]; other site
979556002704	S8 interaction site; other site
979556002705	16S rRNA interaction site [nucleotide binding]; other site
979556002706	streptomycin interaction site [chemical binding]; other site
979556002707	23S rRNA interaction site [nucleotide binding]; other site
979556002708	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
979556002709	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
979556002710	phosphopeptide binding site; other site
979556002711	Transglutaminase/protease-like homologues; Region: TGc; smart00460
979556002712	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
979556002713	Protein of unknown function DUF58; Region: DUF58; pfam01882
979556002714	MoxR-like ATPases [General function prediction only]; Region: COG0714
979556002715	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556002716	Walker A motif; other site
979556002717	ATP binding site [chemical binding]; other site
979556002718	Walker B motif; other site
979556002719	arginine finger; other site
979556002720	Protein kinase domain; Region: Pkinase; pfam00069
979556002721	Catalytic domain of Protein Kinases; Region: PKc; cd00180
979556002722	active site
979556002723	ATP binding site [chemical binding]; other site
979556002724	substrate binding site [chemical binding]; other site
979556002725	activation loop (A-loop); other site
979556002726	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
979556002727	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
979556002728	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
979556002729	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
979556002730	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
979556002731	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
979556002732	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
979556002733	G-loop; other site
979556002734	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
979556002735	DNA binding site [nucleotide binding]
979556002736	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
979556002737	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
979556002738	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
979556002739	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
979556002740	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
979556002741	RPB10 interaction site [polypeptide binding]; other site
979556002742	RPB1 interaction site [polypeptide binding]; other site
979556002743	RPB11 interaction site [polypeptide binding]; other site
979556002744	RPB3 interaction site [polypeptide binding]; other site
979556002745	RPB12 interaction site [polypeptide binding]; other site
979556002746	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
979556002747	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
979556002748	Allophanate hydrolase subunit 2; Region: AHS2; pfam02626
979556002749	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
979556002750	putative active site [active]
979556002751	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556002752	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556002753	Walker A/P-loop; other site
979556002754	ATP binding site [chemical binding]; other site
979556002755	Q-loop/lid; other site
979556002756	ABC transporter signature motif; other site
979556002757	Walker B; other site
979556002758	D-loop; other site
979556002759	H-loop/switch region; other site
979556002760	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556002761	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556002762	Walker A/P-loop; other site
979556002763	ATP binding site [chemical binding]; other site
979556002764	Q-loop/lid; other site
979556002765	ABC transporter signature motif; other site
979556002766	Walker B; other site
979556002767	D-loop; other site
979556002768	H-loop/switch region; other site
979556002769	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556002770	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
979556002771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002772	dimer interface [polypeptide binding]; other site
979556002773	conserved gate region; other site
979556002774	putative PBP binding loops; other site
979556002775	ABC-ATPase subunit interface; other site
979556002776	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556002777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002778	dimer interface [polypeptide binding]; other site
979556002779	conserved gate region; other site
979556002780	putative PBP binding loops; other site
979556002781	ABC-ATPase subunit interface; other site
979556002782	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556002783	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
979556002784	peptide binding site [polypeptide binding]; other site
979556002785	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
979556002786	S-adenosylmethionine binding site [chemical binding]; other site
979556002787	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556002788	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556002789	active site
979556002790	phosphorylation site [posttranslational modification]
979556002791	intermolecular recognition site; other site
979556002792	dimerization interface [polypeptide binding]; other site
979556002793	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556002794	DNA binding residues [nucleotide binding]
979556002795	dimerization interface [polypeptide binding]; other site
979556002796	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556002797	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556002798	ATP binding site [chemical binding]; other site
979556002799	Mg2+ binding site [ion binding]; other site
979556002800	G-X-G motif; other site
979556002801	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556002802	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
979556002803	putative DNA binding site [nucleotide binding]; other site
979556002804	putative Zn2+ binding site [ion binding]; other site
979556002805	AsnC family; Region: AsnC_trans_reg; pfam01037
979556002806	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556002807	active site
979556002808	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
979556002809	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556002810	ATP binding site [chemical binding]; other site
979556002811	putative Mg++ binding site [ion binding]; other site
979556002812	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556002813	nucleotide binding region [chemical binding]; other site
979556002814	ATP-binding site [chemical binding]; other site
979556002815	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
979556002816	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
979556002817	tetramer interface [polypeptide binding]; other site
979556002818	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556002819	catalytic residue [active]
979556002820	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
979556002821	Zn binding site [ion binding]; other site
979556002822	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
979556002823	nudix motif; other site
979556002824	putative hydrolase; Provisional; Region: PRK11460
979556002825	Predicted esterase [General function prediction only]; Region: COG0400
979556002826	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
979556002827	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556002828	Walker A/P-loop; other site
979556002829	ATP binding site [chemical binding]; other site
979556002830	Q-loop/lid; other site
979556002831	ABC transporter signature motif; other site
979556002832	Walker B; other site
979556002833	D-loop; other site
979556002834	H-loop/switch region; other site
979556002835	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556002836	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556002837	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
979556002838	ATP binding site [chemical binding]; other site
979556002839	putative Mg++ binding site [ion binding]; other site
979556002840	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556002841	nucleotide binding region [chemical binding]; other site
979556002842	ATP-binding site [chemical binding]; other site
979556002843	DEAD/H associated; Region: DEAD_assoc; pfam08494
979556002844	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
979556002845	N-terminal domain of the actinomycetal Nei2 and related DNA glycosylases; Region: AcNei2_N; cd08971
979556002846	putative DNA binding site [nucleotide binding]; other site
979556002847	catalytic residue [active]
979556002848	putative H2TH interface [polypeptide binding]; other site
979556002849	putative catalytic residues [active]
979556002850	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556002851	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
979556002852	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
979556002853	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
979556002854	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
979556002855	dimerization interface [polypeptide binding]; other site
979556002856	putative hydrolase, CocE/NonD family; Region: /NonD; TIGR00976
979556002857	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; cl08482
979556002858	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
979556002859	catalytic triad [active]
979556002860	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
979556002861	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
979556002862	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
979556002863	catalytic site [active]
979556002864	active site
979556002865	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
979556002866	maltooligosyl trehalose synthase; Provisional; Region: PRK14511
979556002867	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
979556002868	active site
979556002869	catalytic site [active]
979556002870	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
979556002871	active site
979556002872	catalytic site [active]
979556002873	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
979556002874	synthetase active site [active]
979556002875	NTP binding site [chemical binding]; other site
979556002876	metal binding site [ion binding]; metal-binding site
979556002877	MarR family; Region: MarR_2; pfam12802
979556002878	MarR family; Region: MarR_2; pfam12802
979556002879	Protein of unknown function (DUF3072); Region: DUF3072; pfam11272
979556002880	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556002881	hypothetical protein; Provisional; Region: PRK06149
979556002882	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556002883	inhibitor-cofactor binding pocket; inhibition site
979556002884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556002885	catalytic residue [active]
979556002886	amino acid transporter; Region: 2A0306; TIGR00909
979556002887	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
979556002888	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
979556002889	active site
979556002890	tetracycline repressor protein TetR; Provisional; Region: PRK13756
979556002891	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556002892	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
979556002893	Domain of Unknown Function (DUF1206); Region: DUF1206; pfam06724
979556002894	Domain of Unknown Function (DUF1206); Region: DUF1206; pfam06724
979556002895	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
979556002896	active site
979556002897	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
979556002898	VbhA antitoxin and related proteins; Region: VbhA_like; cd11586
979556002899	FIC domain binding interface [polypeptide binding]; other site
979556002900	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
979556002901	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
979556002902	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
979556002903	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_5; cd09621
979556002904	putative ligand binding site [chemical binding]; other site
979556002905	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556002906	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556002907	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002908	dimer interface [polypeptide binding]; other site
979556002909	conserved gate region; other site
979556002910	putative PBP binding loops; other site
979556002911	ABC-ATPase subunit interface; other site
979556002912	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556002913	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556002914	dimer interface [polypeptide binding]; other site
979556002915	conserved gate region; other site
979556002916	putative PBP binding loops; other site
979556002917	ABC-ATPase subunit interface; other site
979556002918	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556002919	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556002920	NAD(P) binding site [chemical binding]; other site
979556002921	active site
979556002922	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
979556002923	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
979556002924	metal binding site [ion binding]; metal-binding site
979556002925	substrate binding pocket [chemical binding]; other site
979556002926	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
979556002927	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
979556002928	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556002929	substrate binding site [chemical binding]; other site
979556002930	ATP binding site [chemical binding]; other site
979556002931	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
979556002932	active site
979556002933	catalytic residues [active]
979556002934	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556002935	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556002936	DNA binding site [nucleotide binding]
979556002937	domain linker motif; other site
979556002938	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556002939	dimerization interface [polypeptide binding]; other site
979556002940	ligand binding site [chemical binding]; other site
979556002941	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
979556002942	pantoate--beta-alanine ligase; Region: panC; TIGR00018
979556002943	Pantoate-beta-alanine ligase; Region: PanC; cd00560
979556002944	active site
979556002945	ATP-binding site [chemical binding]; other site
979556002946	pantoate-binding site; other site
979556002947	HXXH motif; other site
979556002948	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
979556002949	oligomerization interface [polypeptide binding]; other site
979556002950	active site
979556002951	metal binding site [ion binding]; metal-binding site
979556002952	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
979556002953	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
979556002954	NAD(P) binding site [chemical binding]; other site
979556002955	LDH/MDH dimer interface [polypeptide binding]; other site
979556002956	substrate binding site [chemical binding]; other site
979556002957	DNA repair protein RadA; Provisional; Region: PRK11823
979556002958	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
979556002959	Walker A motif; other site
979556002960	ATP binding site [chemical binding]; other site
979556002961	Walker B motif; other site
979556002962	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556002963	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556002964	DNA-binding site [nucleotide binding]; DNA binding site
979556002965	FCD domain; Region: FCD; pfam07729
979556002966	short chain dehydrogenase; Provisional; Region: PRK06057
979556002967	classical (c) SDRs; Region: SDR_c; cd05233
979556002968	NAD(P) binding site [chemical binding]; other site
979556002969	active site
979556002970	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
979556002971	NAD(P)+ dependent aldehyde dehydrogenase family; Region: ALDH; cd07078
979556002972	NAD(P) binding site [chemical binding]; other site
979556002973	catalytic residues [active]
979556002974	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
979556002975	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
979556002976	catalytic triad [active]
979556002977	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
979556002978	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
979556002979	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556002980	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556002981	Coenzyme A binding pocket [chemical binding]; other site
979556002982	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
979556002983	Clp amino terminal domain; Region: Clp_N; pfam02861
979556002984	Clp amino terminal domain; Region: Clp_N; pfam02861
979556002985	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556002986	Walker A motif; other site
979556002987	ATP binding site [chemical binding]; other site
979556002988	Walker B motif; other site
979556002989	arginine finger; other site
979556002990	UvrB/uvrC motif; Region: UVR; pfam02151
979556002991	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556002992	Walker A motif; other site
979556002993	ATP binding site [chemical binding]; other site
979556002994	Walker B motif; other site
979556002995	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
979556002996	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556002997	non-specific DNA binding site [nucleotide binding]; other site
979556002998	salt bridge; other site
979556002999	sequence-specific DNA binding site [nucleotide binding]; other site
979556003000	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
979556003001	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
979556003002	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
979556003003	putative active site [active]
979556003004	catalytic site [active]
979556003005	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
979556003006	putative active site [active]
979556003007	catalytic site [active]
979556003008	Domain of unknown function (DUF4192); Region: DUF4192; pfam13830
979556003009	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
979556003010	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
979556003011	putative anticodon binding site; other site
979556003012	dimer interface [polypeptide binding]; other site
979556003013	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
979556003014	motif 1; other site
979556003015	dimer interface [polypeptide binding]; other site
979556003016	active site
979556003017	motif 2; other site
979556003018	motif 3; other site
979556003019	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556003020	pantoate--beta-alanine ligase; Region: panC; TIGR00018
979556003021	active site
979556003022	nucleotide binding site [chemical binding]; other site
979556003023	HIGH motif; other site
979556003024	KMSKS motif; other site
979556003025	Rossmann-like domain; Region: Rossmann-like; pfam10727
979556003026	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
979556003027	Bacterial PH domain; Region: DUF304; pfam03703
979556003028	Bacterial PH domain; Region: DUF304; cl01348
979556003029	Bacterial PH domain; Region: DUF304; pfam03703
979556003030	Uncharacterized conserved protein [Function unknown]; Region: COG3402
979556003031	Protein of unknown function (DUF3180); Region: DUF3180; pfam11377
979556003032	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
979556003033	catalytic center binding site [active]
979556003034	ATP binding site [chemical binding]; other site
979556003035	Dihydroneopterin aldolase; Region: FolB; pfam02152
979556003036	active site
979556003037	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
979556003038	dihydropteroate synthase; Region: DHPS; TIGR01496
979556003039	substrate binding pocket [chemical binding]; other site
979556003040	dimer interface [polypeptide binding]; other site
979556003041	inhibitor binding site; inhibition site
979556003042	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
979556003043	GTP cyclohydrolase I; Provisional; Region: PLN03044
979556003044	active site
979556003045	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
979556003046	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556003047	Walker A motif; other site
979556003048	ATP binding site [chemical binding]; other site
979556003049	Walker B motif; other site
979556003050	arginine finger; other site
979556003051	Peptidase family M41; Region: Peptidase_M41; pfam01434
979556003052	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556003053	active site
979556003054	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
979556003055	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
979556003056	Ligand Binding Site [chemical binding]; other site
979556003057	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
979556003058	dimer interface [polypeptide binding]; other site
979556003059	substrate binding site [chemical binding]; other site
979556003060	metal binding sites [ion binding]; metal-binding site
979556003061	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
979556003062	Peptidase family M23; Region: Peptidase_M23; pfam01551
979556003063	Homeodomain-like domain; Region: HTH_23; pfam13384
979556003064	Integrase core domain; Region: rve; pfam00665
979556003065	Integrase core domain; Region: rve_3; pfam13683
979556003066	DNA methylase; Region: N6_N4_Mtase; pfam01555
979556003067	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
979556003068	DGQHR domain; Region: DGQHR; TIGR03187
979556003069	DNA phosphorothioation-associated DGQHR protein 1; Region: DGQHR_dnd_1; TIGR04172
979556003070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003071	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556003072	putative substrate translocation pore; other site
979556003073	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003074	4-coumarate--CoA ligase; Region: PLN02246
979556003075	4-Coumarate-CoA Ligase (4CL); Region: 4CL; cd05904
979556003076	acyl-activating enzyme (AAE) consensus motif; other site
979556003077	active site
979556003078	putative CoA binding site [chemical binding]; other site
979556003079	AMP binding site [chemical binding]; other site
979556003080	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
979556003081	Chromate transporter; Region: Chromate_transp; pfam02417
979556003082	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556003083	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556003084	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
979556003085	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
979556003086	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
979556003087	Ligand binding site; other site
979556003088	Putative Catalytic site; other site
979556003089	DXD motif; other site
979556003090	Predicted membrane protein [Function unknown]; Region: COG2246
979556003091	GtrA-like protein; Region: GtrA; pfam04138
979556003092	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
979556003093	catalytic residues [active]
979556003094	kynureninase; Region: kynureninase; TIGR01814
979556003095	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556003096	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556003097	catalytic residue [active]
979556003098	MarR family; Region: MarR_2; cl17246
979556003099	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556003100	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556003101	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
979556003102	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
979556003103	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
979556003104	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
979556003105	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003106	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556003107	ligand binding site [chemical binding]; other site
979556003108	dimerization interface [polypeptide binding]; other site
979556003109	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
979556003110	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
979556003111	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
979556003112	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556003113	Walker A/P-loop; other site
979556003114	ATP binding site [chemical binding]; other site
979556003115	Q-loop/lid; other site
979556003116	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
979556003117	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556003118	Walker A/P-loop; other site
979556003119	ATP binding site [chemical binding]; other site
979556003120	Q-loop/lid; other site
979556003121	ABC transporter signature motif; other site
979556003122	Walker B; other site
979556003123	D-loop; other site
979556003124	H-loop/switch region; other site
979556003125	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
979556003126	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
979556003127	ATP binding site [chemical binding]; other site
979556003128	Mg++ binding site [ion binding]; other site
979556003129	motif III; other site
979556003130	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556003131	nucleotide binding region [chemical binding]; other site
979556003132	ATP-binding site [chemical binding]; other site
979556003133	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
979556003134	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
979556003135	active site pocket [active]
979556003136	oxyanion hole [active]
979556003137	catalytic triad [active]
979556003138	active site nucleophile [active]
979556003139	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
979556003140	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
979556003141	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
979556003142	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556003143	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003144	dimer interface [polypeptide binding]; other site
979556003145	conserved gate region; other site
979556003146	putative PBP binding loops; other site
979556003147	ABC-ATPase subunit interface; other site
979556003148	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003149	dimer interface [polypeptide binding]; other site
979556003150	conserved gate region; other site
979556003151	putative PBP binding loops; other site
979556003152	ABC-ATPase subunit interface; other site
979556003153	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003154	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556003155	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003156	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556003157	Domain of Unknown Function with PDB structure (DUF3863); Region: DUF3863; pfam12979
979556003158	Domain of Unknown Function with PDB structure (DUF3864); Region: DUF3864; pfam12980
979556003159	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
979556003160	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
979556003161	Fic/DOC family; Region: Fic; cl00960
979556003162	Predicted transcriptional regulator [Transcription]; Region: COG3905
979556003163	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556003164	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556003165	NAD(P) binding site [chemical binding]; other site
979556003166	active site
979556003167	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
979556003168	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
979556003169	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
979556003170	putative active site [active]
979556003171	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
979556003172	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
979556003173	NAD binding site [chemical binding]; other site
979556003174	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003175	active site
979556003176	glucose-6-phosphate isomerase; Provisional; Region: PRK04190
979556003177	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
979556003178	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
979556003179	intersubunit interface [polypeptide binding]; other site
979556003180	active site
979556003181	catalytic residue [active]
979556003182	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
979556003183	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
979556003184	NAD(P) binding site [chemical binding]; other site
979556003185	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
979556003186	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_2; cd07805
979556003187	N- and C-terminal domain interface [polypeptide binding]; other site
979556003188	active site
979556003189	MgATP binding site [chemical binding]; other site
979556003190	catalytic site [active]
979556003191	metal binding site [ion binding]; metal-binding site
979556003192	xylulose binding site [chemical binding]; other site
979556003193	putative homodimer interface [polypeptide binding]; other site
979556003194	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
979556003195	classical (c) SDRs; Region: SDR_c; cd05233
979556003196	NAD(P) binding site [chemical binding]; other site
979556003197	active site
979556003198	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
979556003199	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
979556003200	active site
979556003201	intersubunit interface [polypeptide binding]; other site
979556003202	catalytic residue [active]
979556003203	Fn3 associated; Region: Fn3_assoc; pfam13287
979556003204	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
979556003205	acyl-coenzyme A oxidase; Region: PLN02636
979556003206	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556003207	active site
979556003208	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
979556003209	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556003210	ATP binding site [chemical binding]; other site
979556003211	putative Mg++ binding site [ion binding]; other site
979556003212	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556003213	nucleotide binding region [chemical binding]; other site
979556003214	ATP-binding site [chemical binding]; other site
979556003215	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
979556003216	HRDC domain; Region: HRDC; pfam00570
979556003217	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
979556003218	Na binding site [ion binding]; other site
979556003219	CGNR zinc finger; Region: zf-CGNR; pfam11706
979556003220	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
979556003221	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556003222	active site
979556003223	phosphorylation site [posttranslational modification]
979556003224	intermolecular recognition site; other site
979556003225	dimerization interface [polypeptide binding]; other site
979556003226	LytTr DNA-binding domain; Region: LytTR; smart00850
979556003227	Histidine kinase; Region: His_kinase; pfam06580
979556003228	Protein of unknown function (DUF466); Region: DUF466; pfam04328
979556003229	carbon starvation protein A; Provisional; Region: PRK15015
979556003230	Carbon starvation protein CstA; Region: CstA; pfam02554
979556003231	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
979556003232	Predicted acetyltransferase [General function prediction only]; Region: COG2388
979556003233	Pirin-related protein [General function prediction only]; Region: COG1741
979556003234	Pirin; Region: Pirin; pfam02678
979556003235	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
979556003236	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
979556003237	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
979556003238	Walker A/P-loop; other site
979556003239	ATP binding site [chemical binding]; other site
979556003240	Q-loop/lid; other site
979556003241	ABC transporter signature motif; other site
979556003242	Walker B; other site
979556003243	D-loop; other site
979556003244	H-loop/switch region; other site
979556003245	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
979556003246	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
979556003247	Walker A/P-loop; other site
979556003248	ATP binding site [chemical binding]; other site
979556003249	Q-loop/lid; other site
979556003250	ABC transporter signature motif; other site
979556003251	Walker B; other site
979556003252	D-loop; other site
979556003253	H-loop/switch region; other site
979556003254	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
979556003255	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
979556003256	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
979556003257	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556003258	Walker A motif; other site
979556003259	ATP binding site [chemical binding]; other site
979556003260	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
979556003261	protein-splicing catalytic site; other site
979556003262	thioester formation/cholesterol transfer; other site
979556003263	Hint (Hedgehog/Intein) domain C-terminal region; Region: HintC; smart00305
979556003264	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
979556003265	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
979556003266	DEAD-like helicases superfamily; Region: DEXDc; smart00487
979556003267	ATP binding site [chemical binding]; other site
979556003268	putative Mg++ binding site [ion binding]; other site
979556003269	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556003270	nucleotide binding region [chemical binding]; other site
979556003271	ATP-binding site [chemical binding]; other site
979556003272	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
979556003273	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
979556003274	active site
979556003275	catalytic residues [active]
979556003276	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
979556003277	Protein export membrane protein; Region: SecD_SecF; cl14618
979556003278	CrcB-like protein; Region: CRCB; cl09114
979556003279	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
979556003280	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556003281	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
979556003282	hydrophobic ligand binding site; other site
979556003283	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
979556003284	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556003285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
979556003286	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556003287	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556003288	MFS/sugar transport protein; Region: MFS_2; pfam13347
979556003289	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
979556003290	Methylomonas sp. 4,4'-diapolycopene-dialdehyde dehydrogenase-like; Region: ALDH_DDALDH; cd07099
979556003291	NAD(P) binding site [chemical binding]; other site
979556003292	catalytic residues [active]
979556003293	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596
979556003294	intersubunit interface [polypeptide binding]; other site
979556003295	active site
979556003296	Zn2+ binding site [ion binding]; other site
979556003297	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
979556003298	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556003299	substrate binding site [chemical binding]; other site
979556003300	ATP binding site [chemical binding]; other site
979556003301	CrcB-like protein; Region: CRCB; pfam02537
979556003302	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
979556003303	Cation efflux family; Region: Cation_efflux; pfam01545
979556003304	Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569
979556003305	Eukaryotic DNA topoisomerase I, catalytic core; Region: Topoisom_I; pfam01028
979556003306	active site
979556003307	DNA binding site [nucleotide binding]
979556003308	Int/Topo IB signature motif; other site
979556003309	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
979556003310	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
979556003311	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556003312	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556003313	putative DNA binding site [nucleotide binding]; other site
979556003314	dimerization interface [polypeptide binding]; other site
979556003315	putative Zn2+ binding site [ion binding]; other site
979556003316	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
979556003317	Ligand Binding Site [chemical binding]; other site
979556003318	Protein of unknown function (DUF3073); Region: DUF3073; pfam11273
979556003319	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
979556003320	amidophosphoribosyltransferase; Provisional; Region: PRK09246
979556003321	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
979556003322	active site
979556003323	tetramer interface [polypeptide binding]; other site
979556003324	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556003325	active site
979556003326	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
979556003327	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
979556003328	dimerization interface [polypeptide binding]; other site
979556003329	putative ATP binding site [chemical binding]; other site
979556003330	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
979556003331	putative active site [active]
979556003332	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
979556003333	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
979556003334	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
979556003335	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
979556003336	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
979556003337	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556003338	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
979556003339	substrate binding site [chemical binding]; other site
979556003340	ATP binding site [chemical binding]; other site
979556003341	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
979556003342	active site
979556003343	intersubunit interface [polypeptide binding]; other site
979556003344	catalytic residue [active]
979556003345	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
979556003346	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
979556003347	metal binding site [ion binding]; metal-binding site
979556003348	substrate binding pocket [chemical binding]; other site
979556003349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003350	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556003351	putative substrate translocation pore; other site
979556003352	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
979556003353	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
979556003354	putative NAD(P) binding site [chemical binding]; other site
979556003355	catalytic Zn binding site [ion binding]; other site
979556003356	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
979556003357	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
979556003358	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
979556003359	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003360	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556003361	DNA binding site [nucleotide binding]
979556003362	domain linker motif; other site
979556003363	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556003364	dimerization interface [polypeptide binding]; other site
979556003365	ligand binding site [chemical binding]; other site
979556003366	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
979556003367	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
979556003368	active site
979556003369	TDP-binding site; other site
979556003370	acceptor substrate-binding pocket; other site
979556003371	homodimer interface [polypeptide binding]; other site
979556003372	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556003373	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556003374	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
979556003375	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556003376	dimer interface [polypeptide binding]; other site
979556003377	phosphorylation site [posttranslational modification]
979556003378	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556003379	ATP binding site [chemical binding]; other site
979556003380	Mg2+ binding site [ion binding]; other site
979556003381	G-X-G motif; other site
979556003382	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003383	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556003384	putative substrate translocation pore; other site
979556003385	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003386	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556003387	Transcriptional regulator PadR-like family; Region: PadR; cl17335
979556003388	BCCT family transporter; Region: BCCT; pfam02028
979556003389	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
979556003390	active site
979556003391	ATP binding site [chemical binding]; other site
979556003392	substrate binding site [chemical binding]; other site
979556003393	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
979556003394	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003395	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556003396	DNA binding site [nucleotide binding]
979556003397	domain linker motif; other site
979556003398	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
979556003399	putative dimerization interface [polypeptide binding]; other site
979556003400	putative ligand binding site [chemical binding]; other site
979556003401	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003402	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003403	dimer interface [polypeptide binding]; other site
979556003404	conserved gate region; other site
979556003405	putative PBP binding loops; other site
979556003406	ABC-ATPase subunit interface; other site
979556003407	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556003408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003409	dimer interface [polypeptide binding]; other site
979556003410	conserved gate region; other site
979556003411	putative PBP binding loops; other site
979556003412	ABC-ATPase subunit interface; other site
979556003413	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
979556003414	active site
979556003415	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556003416	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
979556003417	putative substrate binding site [chemical binding]; other site
979556003418	putative ATP binding site [chemical binding]; other site
979556003419	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
979556003420	active site
979556003421	catalytic site [active]
979556003422	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
979556003423	Cna protein B-type domain; Region: Cna_B; pfam05738
979556003424	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
979556003425	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556003426	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556003427	DNA binding residues [nucleotide binding]
979556003428	dimerization interface [polypeptide binding]; other site
979556003429	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14853
979556003430	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
979556003431	nudix motif; other site
979556003432	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
979556003433	active site
979556003434	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556003435	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
979556003436	DNA binding residues [nucleotide binding]
979556003437	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
979556003438	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003439	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556003440	DNA binding site [nucleotide binding]
979556003441	domain linker motif; other site
979556003442	Ligand binding domain of a transcription regulator of cellulose genes, CelR, which is highly homologous to the LacI-GalR family of bacterial transcription regulators; Region: PBP1_CelR; cd06295
979556003443	putative dimerization interface [polypeptide binding]; other site
979556003444	putative ligand binding site [chemical binding]; other site
979556003445	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
979556003446	beta-galactosidase; Region: BGL; TIGR03356
979556003447	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556003448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003449	dimer interface [polypeptide binding]; other site
979556003450	conserved gate region; other site
979556003451	putative PBP binding loops; other site
979556003452	ABC-ATPase subunit interface; other site
979556003453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003454	dimer interface [polypeptide binding]; other site
979556003455	conserved gate region; other site
979556003456	ABC-ATPase subunit interface; other site
979556003457	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003458	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556003459	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; cl00789
979556003460	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
979556003461	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
979556003462	putative active site [active]
979556003463	catalytic triad [active]
979556003464	transcriptional regulator protein; Region: phnR; TIGR03337
979556003465	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556003466	DNA-binding site [nucleotide binding]; DNA binding site
979556003467	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
979556003468	Carboxylesterase family; Region: COesterase; pfam00135
979556003469	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556003470	substrate binding pocket [chemical binding]; other site
979556003471	catalytic triad [active]
979556003472	Ureidoglycolate hydrolase; Region: Ureidogly_hydro; cl01250
979556003473	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
979556003474	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556003475	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Region: 2-Hacid_dh; pfam00389
979556003476	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_7; cd12166
979556003477	putative ligand binding site [chemical binding]; other site
979556003478	putative NAD binding site [chemical binding]; other site
979556003479	catalytic site [active]
979556003480	Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; Region: MltB; COG2951
979556003481	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
979556003482	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556003483	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556003484	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556003485	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556003486	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556003487	TM-ABC transporter signature motif; other site
979556003488	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556003489	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556003490	Walker A/P-loop; other site
979556003491	ATP binding site [chemical binding]; other site
979556003492	Q-loop/lid; other site
979556003493	ABC transporter signature motif; other site
979556003494	Walker B; other site
979556003495	D-loop; other site
979556003496	H-loop/switch region; other site
979556003497	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556003498	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
979556003499	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
979556003500	putative ligand binding site [chemical binding]; other site
979556003501	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556003502	active site
979556003503	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
979556003504	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
979556003505	XdhC Rossmann domain; Region: XdhC_C; pfam13478
979556003506	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003507	active site
979556003508	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
979556003509	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556003510	non-specific DNA binding site [nucleotide binding]; other site
979556003511	salt bridge; other site
979556003512	sequence-specific DNA binding site [nucleotide binding]; other site
979556003513	Cupin domain; Region: Cupin_2; pfam07883
979556003514	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
979556003515	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
979556003516	FMN-binding pocket [chemical binding]; other site
979556003517	flavin binding motif; other site
979556003518	phosphate binding motif [ion binding]; other site
979556003519	beta-alpha-beta structure motif; other site
979556003520	NAD binding pocket [chemical binding]; other site
979556003521	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
979556003522	catalytic loop [active]
979556003523	iron binding site [ion binding]; other site
979556003524	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
979556003525	catalytic loop [active]
979556003526	iron binding site [ion binding]; other site
979556003527	cytosine deaminase; Provisional; Region: PRK05985
979556003528	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
979556003529	active site
979556003530	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
979556003531	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
979556003532	Walker A/P-loop; other site
979556003533	ATP binding site [chemical binding]; other site
979556003534	Q-loop/lid; other site
979556003535	ABC transporter signature motif; other site
979556003536	Walker B; other site
979556003537	D-loop; other site
979556003538	H-loop/switch region; other site
979556003539	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
979556003540	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003541	dimer interface [polypeptide binding]; other site
979556003542	conserved gate region; other site
979556003543	putative PBP binding loops; other site
979556003544	ABC-ATPase subunit interface; other site
979556003545	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
979556003546	FAD binding domain; Region: FAD_binding_4; pfam01565
979556003547	Creatinine amidohydrolase; Region: Creatininase; pfam02633
979556003548	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
979556003549	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556003550	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
979556003551	classical (c) SDRs; Region: SDR_c; cd05233
979556003552	NAD(P) binding site [chemical binding]; other site
979556003553	active site
979556003554	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
979556003555	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
979556003556	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
979556003557	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003558	active site
979556003559	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556003560	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
979556003561	classical (c) SDRs; Region: SDR_c; cd05233
979556003562	NAD(P) binding site [chemical binding]; other site
979556003563	active site
979556003564	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
979556003565	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
979556003566	hypothetical protein; Provisional; Region: PRK07906
979556003567	putative metal binding site [ion binding]; other site
979556003568	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
979556003569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003570	dimer interface [polypeptide binding]; other site
979556003571	conserved gate region; other site
979556003572	putative PBP binding loops; other site
979556003573	ABC-ATPase subunit interface; other site
979556003574	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
979556003575	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
979556003576	Walker A/P-loop; other site
979556003577	ATP binding site [chemical binding]; other site
979556003578	Q-loop/lid; other site
979556003579	ABC transporter signature motif; other site
979556003580	Walker B; other site
979556003581	D-loop; other site
979556003582	H-loop/switch region; other site
979556003583	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556003584	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
979556003585	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
979556003586	substrate binding pocket [chemical binding]; other site
979556003587	membrane-bound complex binding site; other site
979556003588	hinge residues; other site
979556003589	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
979556003590	Uncharacterized conserved protein [Function unknown]; Region: COG0397
979556003591	hypothetical protein; Validated; Region: PRK00029
979556003592	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
979556003593	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556003594	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003595	putative substrate translocation pore; other site
979556003596	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
979556003597	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556003598	Coenzyme A binding pocket [chemical binding]; other site
979556003599	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
979556003600	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
979556003601	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
979556003602	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
979556003603	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
979556003604	active site
979556003605	non-prolyl cis peptide bond; other site
979556003606	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556003607	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556003608	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
979556003609	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556003610	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556003611	Walker A/P-loop; other site
979556003612	ATP binding site [chemical binding]; other site
979556003613	Q-loop/lid; other site
979556003614	ABC transporter signature motif; other site
979556003615	Walker B; other site
979556003616	D-loop; other site
979556003617	H-loop/switch region; other site
979556003618	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
979556003619	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556003620	Walker A/P-loop; other site
979556003621	ATP binding site [chemical binding]; other site
979556003622	Q-loop/lid; other site
979556003623	ABC transporter signature motif; other site
979556003624	Walker B; other site
979556003625	D-loop; other site
979556003626	H-loop/switch region; other site
979556003627	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556003628	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556003629	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003630	ABC-ATPase subunit interface; other site
979556003631	putative PBP binding loops; other site
979556003632	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556003633	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556003634	Fatty acid desaturase; Region: FA_desaturase; pfam00487
979556003635	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
979556003636	putative di-iron ligands [ion binding]; other site
979556003637	GAF domain; Region: GAF; pfam01590
979556003638	ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; Region: ANTAR; smart01012
979556003639	amino acid transporter; Region: 2A0306; TIGR00909
979556003640	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
979556003641	putative substrate binding site [chemical binding]; other site
979556003642	putative ATP binding site [chemical binding]; other site
979556003643	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556003644	catalytic core [active]
979556003645	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556003646	Histidine kinase; Region: HisKA_3; pfam07730
979556003647	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556003648	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556003649	active site
979556003650	phosphorylation site [posttranslational modification]
979556003651	intermolecular recognition site; other site
979556003652	dimerization interface [polypeptide binding]; other site
979556003653	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556003654	DNA binding residues [nucleotide binding]
979556003655	dimerization interface [polypeptide binding]; other site
979556003656	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
979556003657	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
979556003658	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
979556003659	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
979556003660	hydrophobic ligand binding site; other site
979556003661	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556003662	Coenzyme A binding pocket [chemical binding]; other site
979556003663	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
979556003664	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
979556003665	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
979556003666	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
979556003667	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
979556003668	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
979556003669	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556003670	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556003671	homodimer interface [polypeptide binding]; other site
979556003672	catalytic residue [active]
979556003673	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556003674	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556003675	Walker A/P-loop; other site
979556003676	ATP binding site [chemical binding]; other site
979556003677	Q-loop/lid; other site
979556003678	ABC transporter signature motif; other site
979556003679	Walker B; other site
979556003680	D-loop; other site
979556003681	H-loop/switch region; other site
979556003682	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556003683	Walker A/P-loop; other site
979556003684	ATP binding site [chemical binding]; other site
979556003685	Q-loop/lid; other site
979556003686	ABC transporter signature motif; other site
979556003687	Walker B; other site
979556003688	D-loop; other site
979556003689	H-loop/switch region; other site
979556003690	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556003691	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556003692	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003693	dimer interface [polypeptide binding]; other site
979556003694	conserved gate region; other site
979556003695	putative PBP binding loops; other site
979556003696	ABC-ATPase subunit interface; other site
979556003697	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556003698	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556003699	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003700	dimer interface [polypeptide binding]; other site
979556003701	conserved gate region; other site
979556003702	putative PBP binding loops; other site
979556003703	ABC-ATPase subunit interface; other site
979556003704	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556003705	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
979556003706	FAD binding domain; Region: FAD_binding_4; pfam01565
979556003707	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
979556003708	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556003709	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
979556003710	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
979556003711	active site
979556003712	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
979556003713	non-prolyl cis peptide bond; other site
979556003714	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
979556003715	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556003716	MarR family; Region: MarR_2; cl17246
979556003717	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
979556003718	hydrophobic ligand binding site; other site
979556003719	Methylene-tetrahydrofolate reductase C terminal; Region: MTHFR_C; pfam12225
979556003720	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
979556003721	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
979556003722	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
979556003723	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
979556003724	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
979556003725	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
979556003726	catalytic loop [active]
979556003727	iron binding site [ion binding]; other site
979556003728	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
979556003729	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
979556003730	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; cl03161
979556003731	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
979556003732	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
979556003733	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
979556003734	allantoate amidohydrolase; Reviewed; Region: PRK09290
979556003735	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
979556003736	active site
979556003737	metal binding site [ion binding]; metal-binding site
979556003738	dimer interface [polypeptide binding]; other site
979556003739	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
979556003740	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556003741	catalytic residue [active]
979556003742	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
979556003743	Amidase; Region: Amidase; cl11426
979556003744	indole-3-acetamide amidohydrolase; Region: PLN02722
979556003745	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
979556003746	allantoinase; Region: allantoinase; TIGR03178
979556003747	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003748	active site
979556003749	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
979556003750	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
979556003751	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
979556003752	Na binding site [ion binding]; other site
979556003753	putative substrate binding site [chemical binding]; other site
979556003754	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556003755	non-specific DNA binding site [nucleotide binding]; other site
979556003756	salt bridge; other site
979556003757	sequence-specific DNA binding site [nucleotide binding]; other site
979556003758	Cupin domain; Region: Cupin_2; pfam07883
979556003759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4861
979556003760	Uncharacterized protein conserved in bacteria (DUF2186); Region: DUF2186; pfam09952
979556003761	Predicted nucleotidyltransferase [General function prediction    only]; Region: COG4849
979556003762	Bacillus subtilis YvnB and related proteins, metallophosphatase domain; Region: MPP_YvnB; cd07399
979556003763	putative active site [active]
979556003764	putative metal binding site [ion binding]; other site
979556003765	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
979556003766	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
979556003767	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cl15820
979556003768	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556003769	OHCU decarboxylase; Region: OHCU_decarbox; cl01251
979556003770	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
979556003771	active site
979556003772	homotetramer interface [polypeptide binding]; other site
979556003773	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
979556003774	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556003775	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
979556003776	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003777	active site
979556003778	amino acid transporter; Region: 2A0306; TIGR00909
979556003779	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556003780	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556003781	active site
979556003782	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins; Region: AmyAc_OligoGlu_TS; cd11332
979556003783	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
979556003784	active site
979556003785	catalytic site [active]
979556003786	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
979556003787	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003788	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556003789	DNA binding site [nucleotide binding]
979556003790	domain linker motif; other site
979556003791	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556003792	ligand binding site [chemical binding]; other site
979556003793	dimerization interface [polypeptide binding]; other site
979556003794	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
979556003795	Septum formation; Region: Septum_form; pfam13845
979556003796	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
979556003797	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556003798	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like6; cd05664
979556003799	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
979556003800	metal binding site [ion binding]; metal-binding site
979556003801	putative dimer interface [polypeptide binding]; other site
979556003802	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
979556003803	putative metal binding site [ion binding]; other site
979556003804	Carbohydrate Binding Module family 35 (CBM35); appended mainly to enzymes that bind alpha-D-galactose (CBM35-Gal), including glycoside hydrolase (GH) families GH31 and GH43; Region: CBM35_galactosidase-like; cd04081
979556003805	Ca binding site [ion binding]; other site
979556003806	Melibiase; Region: Melibiase; pfam02065
979556003807	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003808	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556003809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003810	dimer interface [polypeptide binding]; other site
979556003811	conserved gate region; other site
979556003812	ABC-ATPase subunit interface; other site
979556003813	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556003814	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003815	dimer interface [polypeptide binding]; other site
979556003816	conserved gate region; other site
979556003817	putative PBP binding loops; other site
979556003818	ABC-ATPase subunit interface; other site
979556003819	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556003820	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556003821	DNA binding site [nucleotide binding]
979556003822	domain linker motif; other site
979556003823	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556003824	ligand binding site [chemical binding]; other site
979556003825	dimerization interface (open form) [polypeptide binding]; other site
979556003826	dimerization interface (closed form) [polypeptide binding]; other site
979556003827	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
979556003828	CopC domain; Region: CopC; cl01012
979556003829	Reeler-like domain of YcnI and similar proteins; Region: YcnI_like; cd08545
979556003830	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
979556003831	acyltransferase, WS/DGAT/MGAT; Region: acyl_WS_DGAT; TIGR02946
979556003832	Wax ester synthase-like Acyl-CoA acyltransferase domain; Region: WES_acyltransf; pfam03007
979556003833	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556003834	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556003835	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556003836	K+ potassium transporter; Region: K_trans; cl15781
979556003837	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
979556003838	hypothetical protein; Provisional; Region: PRK09256
979556003839	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
979556003840	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
979556003841	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
979556003842	Soluble P-type ATPase [General function prediction only]; Region: COG4087
979556003843	K+-transporting ATPase, c chain [Inorganic ion transport and metabolism]; Region: KdpC; COG2156
979556003844	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
979556003845	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
979556003846	Ligand Binding Site [chemical binding]; other site
979556003847	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
979556003848	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556003849	ATP binding site [chemical binding]; other site
979556003850	Mg2+ binding site [ion binding]; other site
979556003851	G-X-G motif; other site
979556003852	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
979556003853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556003854	active site
979556003855	phosphorylation site [posttranslational modification]
979556003856	intermolecular recognition site; other site
979556003857	dimerization interface [polypeptide binding]; other site
979556003858	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556003859	DNA binding site [nucleotide binding]
979556003860	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
979556003861	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
979556003862	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556003863	catalytic residue [active]
979556003864	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
979556003865	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
979556003866	trimerization site [polypeptide binding]; other site
979556003867	active site
979556003868	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
979556003869	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
979556003870	putative hydrophobic ligand binding site [chemical binding]; other site
979556003871	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
979556003872	hydrophobic ligand binding site; other site
979556003873	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556003874	dimerization interface [polypeptide binding]; other site
979556003875	putative DNA binding site [nucleotide binding]; other site
979556003876	putative Zn2+ binding site [ion binding]; other site
979556003877	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
979556003878	SnoaL-like domain; Region: SnoaL_2; pfam12680
979556003879	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
979556003880	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556003881	putative DNA binding site [nucleotide binding]; other site
979556003882	putative Zn2+ binding site [ion binding]; other site
979556003883	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
979556003884	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3002
979556003885	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
979556003886	YcfA-like protein; Region: YcfA; cl00752
979556003887	Protein of unknown function (DUF429); Region: DUF429; cl12046
979556003888	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
979556003889	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556003890	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
979556003891	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556003892	putative substrate translocation pore; other site
979556003893	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
979556003894	active site
979556003895	catalytic site [active]
979556003896	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
979556003897	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
979556003898	active site
979556003899	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
979556003900	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
979556003901	Citrate synthase; Region: Citrate_synt; pfam00285
979556003902	oxalacetate binding site [chemical binding]; other site
979556003903	citrylCoA binding site [chemical binding]; other site
979556003904	coenzyme A binding site [chemical binding]; other site
979556003905	catalytic triad [active]
979556003906	Helix-turn-helix domain; Region: HTH_17; pfam12728
979556003907	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
979556003908	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
979556003909	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
979556003910	coenzyme A binding site [chemical binding]; other site
979556003911	citrylCoA binding site [chemical binding]; other site
979556003912	oxalacetate binding site [chemical binding]; other site
979556003913	catalytic triad [active]
979556003914	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
979556003915	PIN domain; Region: PIN; pfam01850
979556003916	putative active site [active]
979556003917	MobA-like NTP transferase domain; Region: NTP_transf_3; pfam12804
979556003918	active site
979556003919	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
979556003920	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
979556003921	dimer interface [polypeptide binding]; other site
979556003922	putative functional site; other site
979556003923	putative MPT binding site; other site
979556003924	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
979556003925	Domain of unknown function (DUF1990); Region: DUF1990; pfam09348
979556003926	Asp23 family; Region: Asp23; pfam03780
979556003927	Asp23 family; Region: Asp23; pfam03780
979556003928	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
979556003929	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
979556003930	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
979556003931	putative molybdopterin cofactor binding site [chemical binding]; other site
979556003932	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
979556003933	putative molybdopterin cofactor binding site; other site
979556003934	hypothetical protein; Provisional; Region: PRK06185
979556003935	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556003936	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
979556003937	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
979556003938	dimerization interface [polypeptide binding]; other site
979556003939	ATP binding site [chemical binding]; other site
979556003940	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
979556003941	dimerization interface [polypeptide binding]; other site
979556003942	ATP binding site [chemical binding]; other site
979556003943	Epoxide hydrolase N terminus; Region: EHN; pfam06441
979556003944	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556003945	Protein of unknown function (DUF3253); Region: DUF3253; pfam11625
979556003946	Uncharacterized conserved protein (COG2071); Region: DUF2071; pfam09844
979556003947	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
979556003948	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
979556003949	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003950	dimer interface [polypeptide binding]; other site
979556003951	conserved gate region; other site
979556003952	putative PBP binding loops; other site
979556003953	ABC-ATPase subunit interface; other site
979556003954	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
979556003955	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
979556003956	Walker A/P-loop; other site
979556003957	ATP binding site [chemical binding]; other site
979556003958	Q-loop/lid; other site
979556003959	ABC transporter signature motif; other site
979556003960	Walker B; other site
979556003961	D-loop; other site
979556003962	H-loop/switch region; other site
979556003963	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
979556003964	chorismate mutase; Provisional; Region: PRK09239
979556003965	Domain of unknown function DUF20; Region: UPF0118; pfam01594
979556003966	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
979556003967	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556003968	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
979556003969	active site
979556003970	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556003971	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556003972	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556003973	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556003974	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
979556003975	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
979556003976	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
979556003977	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003978	dimer interface [polypeptide binding]; other site
979556003979	conserved gate region; other site
979556003980	putative PBP binding loops; other site
979556003981	ABC-ATPase subunit interface; other site
979556003982	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556003983	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556003984	dimer interface [polypeptide binding]; other site
979556003985	conserved gate region; other site
979556003986	putative PBP binding loops; other site
979556003987	ABC-ATPase subunit interface; other site
979556003988	Uncharacterized conserved protein [Function unknown]; Region: COG5476
979556003989	Protein of unknown function (DUF1485); Region: DUF1485; pfam07364
979556003990	MlrC C-terminus; Region: MlrC_C; pfam07171
979556003991	CutC family; Region: CutC; cl01218
979556003992	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556003993	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556003994	nucleotide binding site [chemical binding]; other site
979556003995	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
979556003996	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
979556003997	active site
979556003998	trimer interface [polypeptide binding]; other site
979556003999	allosteric site; other site
979556004000	active site lid [active]
979556004001	hexamer (dimer of trimers) interface [polypeptide binding]; other site
979556004002	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
979556004003	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556004004	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556004005	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
979556004006	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004007	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556004008	DNA binding site [nucleotide binding]
979556004009	domain linker motif; other site
979556004010	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556004011	dimerization interface [polypeptide binding]; other site
979556004012	ligand binding site [chemical binding]; other site
979556004013	Integrase core domain; Region: rve; pfam00665
979556004014	Integrase core domain; Region: rve_3; pfam13683
979556004015	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556004016	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556004017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004018	conserved gate region; other site
979556004019	putative PBP binding loops; other site
979556004020	ABC-ATPase subunit interface; other site
979556004021	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556004022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004023	dimer interface [polypeptide binding]; other site
979556004024	conserved gate region; other site
979556004025	putative PBP binding loops; other site
979556004026	ABC-ATPase subunit interface; other site
979556004027	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
979556004028	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
979556004029	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
979556004030	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
979556004031	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
979556004032	GDP-binding site [chemical binding]; other site
979556004033	ACT binding site; other site
979556004034	IMP binding site; other site
979556004035	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
979556004036	active site
979556004037	argininosuccinate synthase; Validated; Region: PRK05370
979556004038	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556004039	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
979556004040	Predicted membrane protein [Function unknown]; Region: COG1511
979556004041	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
979556004042	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
979556004043	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
979556004044	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
979556004045	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
979556004046	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556004047	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556004048	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556004049	HAMP domain; Region: HAMP; pfam00672
979556004050	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556004051	dimer interface [polypeptide binding]; other site
979556004052	phosphorylation site [posttranslational modification]
979556004053	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556004054	ATP binding site [chemical binding]; other site
979556004055	Mg2+ binding site [ion binding]; other site
979556004056	G-X-G motif; other site
979556004057	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556004058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556004059	active site
979556004060	phosphorylation site [posttranslational modification]
979556004061	intermolecular recognition site; other site
979556004062	dimerization interface [polypeptide binding]; other site
979556004063	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556004064	DNA binding site [nucleotide binding]
979556004065	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
979556004066	FtsX-like permease family; Region: FtsX; pfam02687
979556004067	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556004068	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
979556004069	Walker A/P-loop; other site
979556004070	ATP binding site [chemical binding]; other site
979556004071	Q-loop/lid; other site
979556004072	ABC transporter signature motif; other site
979556004073	Walker B; other site
979556004074	D-loop; other site
979556004075	H-loop/switch region; other site
979556004076	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
979556004077	hydrophobic ligand binding site; other site
979556004078	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
979556004079	FAD binding domain; Region: FAD_binding_2; pfam00890
979556004080	Na+/H+ antiporter subunit; Region: PhaG_MnhG_YufB; pfam03334
979556004081	Multiple resistance and pH regulation protein F (MrpF / PhaF); Region: MrpF_PhaF; cl09154
979556004082	Na+/H+ ion antiporter subunit; Region: MNHE; pfam01899
979556004083	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK12665
979556004084	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
979556004085	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK07946
979556004086	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12644
979556004087	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
979556004088	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
979556004089	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
979556004090	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004091	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556004092	DNA binding site [nucleotide binding]
979556004093	domain linker motif; other site
979556004094	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556004095	hypothetical protein; Provisional; Region: PRK03298
979556004096	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
979556004097	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
979556004098	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
979556004099	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
979556004100	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
979556004101	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
979556004102	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556004103	motif II; other site
979556004104	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
979556004105	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
979556004106	DNA-binding site [nucleotide binding]; DNA binding site
979556004107	RNA-binding motif; other site
979556004108	Transcriptional regulators [Transcription]; Region: GntR; COG1802
979556004109	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556004110	DNA-binding site [nucleotide binding]; DNA binding site
979556004111	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
979556004112	putative catalytic site [active]
979556004113	putative phosphate binding site [ion binding]; other site
979556004114	putative metal binding site [ion binding]; other site
979556004115	Domain of unknown function (DUF368); Region: DUF368; pfam04018
979556004116	Protein of unknown function (DUF2662); Region: DUF3662; pfam12401
979556004117	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
979556004118	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
979556004119	phosphopeptide binding site; other site
979556004120	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
979556004121	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
979556004122	phosphopeptide binding site; other site
979556004123	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
979556004124	active site
979556004125	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
979556004126	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
979556004127	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556004128	Catalytic domain of Protein Kinases; Region: PKc; cd00180
979556004129	active site
979556004130	ATP binding site [chemical binding]; other site
979556004131	substrate binding site [chemical binding]; other site
979556004132	activation loop (A-loop); other site
979556004133	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
979556004134	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556004135	active site
979556004136	ATP binding site [chemical binding]; other site
979556004137	substrate binding site [chemical binding]; other site
979556004138	activation loop (A-loop); other site
979556004139	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556004140	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556004141	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
979556004142	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
979556004143	Glutamine amidotransferase class-I; Region: GATase; pfam00117
979556004144	glutamine binding [chemical binding]; other site
979556004145	catalytic triad [active]
979556004146	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_5; cd05830
979556004147	active site
979556004148	catalytic site [active]
979556004149	Uncharacterized protein family (UPF0233); Region: UPF0233; pfam06781
979556004150	Rhomboid family; Region: Rhomboid; pfam01694
979556004151	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
979556004152	active site
979556004153	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cd04332
979556004154	putative deacylase active site [active]
979556004155	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
979556004156	nudix motif; other site
979556004157	Transmembrane domain of unknown function (DUF3566); Region: DUF3566; pfam12089
979556004158	DNA gyrase subunit A; Validated; Region: PRK05560
979556004159	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
979556004160	CAP-like domain; other site
979556004161	active site
979556004162	primary dimer interface [polypeptide binding]; other site
979556004163	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004164	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004165	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004166	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004167	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004168	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556004169	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
979556004170	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556004171	Mg2+ binding site [ion binding]; other site
979556004172	G-X-G motif; other site
979556004173	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
979556004174	anchoring element; other site
979556004175	dimer interface [polypeptide binding]; other site
979556004176	ATP binding site [chemical binding]; other site
979556004177	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
979556004178	active site
979556004179	putative metal-binding site [ion binding]; other site
979556004180	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
979556004181	Protein of unknown function (DUF721); Region: DUF721; cl02324
979556004182	recombination protein F; Reviewed; Region: recF; PRK00064
979556004183	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
979556004184	Walker A/P-loop; other site
979556004185	ATP binding site [chemical binding]; other site
979556004186	Q-loop/lid; other site
979556004187	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556004188	ABC transporter signature motif; other site
979556004189	Walker B; other site
979556004190	D-loop; other site
979556004191	H-loop/switch region; other site
979556004192	DNA polymerase III subunit beta; Validated; Region: PRK07761
979556004193	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
979556004194	putative DNA binding surface [nucleotide binding]; other site
979556004195	dimer interface [polypeptide binding]; other site
979556004196	beta-clamp/clamp loader binding surface; other site
979556004197	beta-clamp/translesion DNA polymerase binding surface; other site
979556004198	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
979556004199	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556004200	Walker A motif; other site
979556004201	ATP binding site [chemical binding]; other site
979556004202	Walker B motif; other site
979556004203	arginine finger; other site
979556004204	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
979556004205	DnaA box-binding interface [nucleotide binding]; other site
979556004206	Ribosomal protein L34; Region: Ribosomal_L34; cl00370
979556004207	Ribonuclease P; Region: Ribonuclease_P; cl00457
979556004208	Haemolytic domain; Region: Haemolytic; cl00506
979556004209	putative inner membrane protein translocase component YidC; Provisional; Region: PRK01315
979556004210	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
979556004211	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
979556004212	R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich...; Region: R3H; cd02325
979556004213	RxxxH motif; other site
979556004214	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
979556004215	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
979556004216	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
979556004217	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
979556004218	P-loop; other site
979556004219	Magnesium ion binding site [ion binding]; other site
979556004220	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
979556004221	Magnesium ion binding site [ion binding]; other site
979556004222	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
979556004223	ParB-like nuclease domain; Region: ParBc; pfam02195
979556004224	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
979556004225	catalytic residues [active]
979556004226	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
979556004227	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556004228	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556004229	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
979556004230	MviN-like protein; Region: MVIN; pfam03023
979556004231	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
979556004232	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556004233	S-adenosylmethionine binding site [chemical binding]; other site
979556004234	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
979556004235	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
979556004236	active site
979556004237	NTP binding site [chemical binding]; other site
979556004238	metal binding triad [ion binding]; metal-binding site
979556004239	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
979556004240	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
979556004241	Zn2+ binding site [ion binding]; other site
979556004242	Mg2+ binding site [ion binding]; other site
979556004243	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556004244	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
979556004245	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
979556004246	D-arabinose dehydrogenase; Region: arabinose_DH_like; cd05284
979556004247	NAD binding site [chemical binding]; other site
979556004248	substrate binding site [chemical binding]; other site
979556004249	catalytic Zn binding site [ion binding]; other site
979556004250	structural Zn binding site [ion binding]; other site
979556004251	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
979556004252	DNA binding site [nucleotide binding]
979556004253	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
979556004254	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
979556004255	NAD(P) binding site [chemical binding]; other site
979556004256	catalytic residues [active]
979556004257	Protein of unknown function (DUF779); Region: DUF779; pfam05610
979556004258	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556004259	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556004260	active site
979556004261	phosphorylation site [posttranslational modification]
979556004262	intermolecular recognition site; other site
979556004263	dimerization interface [polypeptide binding]; other site
979556004264	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556004265	DNA binding residues [nucleotide binding]
979556004266	dimerization interface [polypeptide binding]; other site
979556004267	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556004268	Histidine kinase; Region: HisKA_3; pfam07730
979556004269	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
979556004270	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
979556004271	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556004272	Walker A/P-loop; other site
979556004273	ATP binding site [chemical binding]; other site
979556004274	Q-loop/lid; other site
979556004275	ABC transporter signature motif; other site
979556004276	Walker B; other site
979556004277	D-loop; other site
979556004278	H-loop/switch region; other site
979556004279	Alpha/beta hydrolase; Region: Abhydrolase_8; pfam06259
979556004280	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
979556004281	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556004282	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
979556004283	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556004284	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556004285	catalytic residue [active]
979556004286	dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021
979556004287	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
979556004288	active site
979556004289	dimer interface [polypeptide binding]; other site
979556004290	non-prolyl cis peptide bond; other site
979556004291	insertion regions; other site
979556004292	Phosphotransferase enzyme family; Region: APH; pfam01636
979556004293	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
979556004294	substrate binding site [chemical binding]; other site
979556004295	putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family; Region: LLM_KPN_01858; TIGR04027
979556004296	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
979556004297	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004298	3-hydroxybutyrate dehydrogenase; Region: PHB_DH; TIGR01963
979556004299	NAD(P) binding site [chemical binding]; other site
979556004300	active site
979556004301	IncA protein; Region: IncA; pfam04156
979556004302	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
979556004303	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
979556004304	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
979556004305	dimer interface [polypeptide binding]; other site
979556004306	ssDNA binding site [nucleotide binding]; other site
979556004307	tetramer (dimer of dimers) interface [polypeptide binding]; other site
979556004308	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
979556004309	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
979556004310	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
979556004311	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
979556004312	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556004313	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
979556004314	active site
979556004315	Cupin superfamily (DUF985); Region: Cupin_5; cl01418
979556004316	replicative DNA helicase; Region: DnaB; TIGR00665
979556004317	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
979556004318	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
979556004319	Walker A motif; other site
979556004320	ATP binding site [chemical binding]; other site
979556004321	Walker B motif; other site
979556004322	DNA binding loops [nucleotide binding]
979556004323	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
979556004324	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
979556004325	putative metal binding site [ion binding]; other site
979556004326	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
979556004327	active site
979556004328	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
979556004329	dimerization interface [polypeptide binding]; other site
979556004330	active site
979556004331	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556004332	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
979556004333	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
979556004334	conserved cys residue [active]
979556004335	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556004336	Domain of unknown function (DUF4386); Region: DUF4386; pfam14329
979556004337	BLMT, a bleomycin resistance protein encoded on the transposon Tn5, and similar proteins; Region: BLMT_like; cd08350
979556004338	dimer interface [polypeptide binding]; other site
979556004339	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556004340	ligand binding site [chemical binding]; other site
979556004341	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
979556004342	GIY-YIG motif/motif A; other site
979556004343	active site
979556004344	catalytic site [active]
979556004345	TIGR03086 family protein; Region: TIGR03086
979556004346	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556004347	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556004348	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
979556004349	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004350	NmrA-like family; Region: NmrA; pfam05368
979556004351	NAD(P) binding site [chemical binding]; other site
979556004352	active site
979556004353	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
979556004354	Part of AAA domain; Region: AAA_19; pfam13245
979556004355	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
979556004356	AAA domain; Region: AAA_12; pfam13087
979556004357	Protein of unknown function (DUF3320); Region: DUF3320; pfam11784
979556004358	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
979556004359	active site
979556004360	catalytic site [active]
979556004361	substrate binding site [chemical binding]; other site
979556004362	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
979556004363	HsdM N-terminal domain; Region: HsdM_N; pfam12161
979556004364	Methyltransferase domain; Region: Methyltransf_26; pfam13659
979556004365	S-adenosylmethionine binding site [chemical binding]; other site
979556004366	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
979556004367	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
979556004368	Mrr N-terminal domain; Region: Mrr_N; pfam14338
979556004369	Restriction endonuclease; Region: Mrr_cat; pfam04471
979556004370	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
979556004371	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
979556004372	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
979556004373	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556004374	ATP binding site [chemical binding]; other site
979556004375	putative Mg++ binding site [ion binding]; other site
979556004376	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
979556004377	dimer interface [polypeptide binding]; other site
979556004378	HTH domain; Region: HTH_11; pfam08279
979556004379	WYL domain; Region: WYL; pfam13280
979556004380	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
979556004381	RibD C-terminal domain; Region: RibD_C; cl17279
979556004382	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556004383	Histidine kinase; Region: HisKA_3; pfam07730
979556004384	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556004385	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556004386	active site
979556004387	phosphorylation site [posttranslational modification]
979556004388	intermolecular recognition site; other site
979556004389	dimerization interface [polypeptide binding]; other site
979556004390	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556004391	DNA binding residues [nucleotide binding]
979556004392	dimerization interface [polypeptide binding]; other site
979556004393	Protein of unknown function DUF86; Region: DUF86; cl01031
979556004394	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556004395	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556004396	sequence-specific DNA binding site [nucleotide binding]; other site
979556004397	salt bridge; other site
979556004398	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
979556004399	active site
979556004400	NTP binding site [chemical binding]; other site
979556004401	metal binding triad [ion binding]; metal-binding site
979556004402	antibiotic binding site [chemical binding]; other site
979556004403	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
979556004404	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
979556004405	FMN binding site [chemical binding]; other site
979556004406	active site
979556004407	substrate binding site [chemical binding]; other site
979556004408	catalytic residue [active]
979556004409	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
979556004410	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
979556004411	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
979556004412	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
979556004413	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
979556004414	G2 box; other site
979556004415	Switch I region; other site
979556004416	G3 box; other site
979556004417	Switch II region; other site
979556004418	G4 box; other site
979556004419	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
979556004420	HEAT repeats; Region: HEAT_2; pfam13646
979556004421	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004422	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556004423	DNA binding site [nucleotide binding]
979556004424	domain linker motif; other site
979556004425	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556004426	ligand binding site [chemical binding]; other site
979556004427	dimerization interface [polypeptide binding]; other site
979556004428	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556004429	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556004430	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
979556004431	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004432	putative PBP binding loops; other site
979556004433	ABC-ATPase subunit interface; other site
979556004434	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556004435	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004436	putative PBP binding loops; other site
979556004437	dimer interface [polypeptide binding]; other site
979556004438	ABC-ATPase subunit interface; other site
979556004439	putative alpha-glucosidase; Provisional; Region: PRK10658
979556004440	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
979556004441	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
979556004442	active site
979556004443	homotrimer interface [polypeptide binding]; other site
979556004444	catalytic site [active]
979556004445	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
979556004446	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
979556004447	active site
979556004448	catalytic triad [active]
979556004449	oxyanion hole [active]
979556004450	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004451	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556004452	DNA binding site [nucleotide binding]
979556004453	domain linker motif; other site
979556004454	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556004455	dimerization interface [polypeptide binding]; other site
979556004456	ligand binding site [chemical binding]; other site
979556004457	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556004458	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556004459	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
979556004460	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
979556004461	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
979556004462	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556004463	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556004464	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
979556004465	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004466	putative PBP binding loops; other site
979556004467	ABC-ATPase subunit interface; other site
979556004468	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556004469	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004470	dimer interface [polypeptide binding]; other site
979556004471	conserved gate region; other site
979556004472	putative PBP binding loops; other site
979556004473	ABC-ATPase subunit interface; other site
979556004474	Right handed beta helix region; Region: Beta_helix; pfam13229
979556004475	Right handed beta helix region; Region: Beta_helix; pfam13229
979556004476	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556004477	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556004478	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
979556004479	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
979556004480	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
979556004481	FAD binding pocket [chemical binding]; other site
979556004482	conserved FAD binding motif [chemical binding]; other site
979556004483	phosphate binding motif [ion binding]; other site
979556004484	beta-alpha-beta structure motif; other site
979556004485	NAD binding pocket [chemical binding]; other site
979556004486	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
979556004487	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
979556004488	Moco binding site; other site
979556004489	metal coordination site [ion binding]; other site
979556004490	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556004491	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556004492	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556004493	sequence-specific DNA binding site [nucleotide binding]; other site
979556004494	salt bridge; other site
979556004495	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556004496	dimerization interface [polypeptide binding]; other site
979556004497	putative DNA binding site [nucleotide binding]; other site
979556004498	putative Zn2+ binding site [ion binding]; other site
979556004499	Cation efflux family; Region: Cation_efflux; cl00316
979556004500	DJ-1 family protein; Region: not_thiJ; TIGR01383
979556004501	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
979556004502	conserved cys residue [active]
979556004503	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
979556004504	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556004505	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556004506	Zn-finger in ubiquitin-hydrolases and other protein; Region: zf-UBP; pfam02148
979556004507	Protein of unknown function (DUF1295); Region: DUF1295; cl17837
979556004508	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
979556004509	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
979556004510	acyl-activating enzyme (AAE) consensus motif; other site
979556004511	putative AMP binding site [chemical binding]; other site
979556004512	putative active site [active]
979556004513	putative CoA binding site [chemical binding]; other site
979556004514	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
979556004515	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
979556004516	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
979556004517	active site
979556004518	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004519	NAD(P) binding site [chemical binding]; other site
979556004520	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
979556004521	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004522	active site
979556004523	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
979556004524	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
979556004525	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
979556004526	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
979556004527	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
979556004528	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
979556004529	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
979556004530	carboxyltransferase (CT) interaction site; other site
979556004531	biotinylation site [posttranslational modification]; other site
979556004532	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
979556004533	putative active site [active]
979556004534	putative catalytic site [active]
979556004535	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
979556004536	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556004537	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556004538	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
979556004539	nudix motif; other site
979556004540	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556004541	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556004542	Walker A/P-loop; other site
979556004543	ATP binding site [chemical binding]; other site
979556004544	Q-loop/lid; other site
979556004545	ABC transporter signature motif; other site
979556004546	Walker B; other site
979556004547	D-loop; other site
979556004548	H-loop/switch region; other site
979556004549	RHS Repeat; Region: RHS_repeat; pfam05593
979556004550	RHS Repeat; Region: RHS_repeat; pfam05593
979556004551	RHS Repeat; Region: RHS_repeat; cl11982
979556004552	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
979556004553	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
979556004554	RHS Repeat; Region: RHS_repeat; pfam05593
979556004555	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
979556004556	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
979556004557	RHS Repeat; Region: RHS_repeat; pfam05593
979556004558	RHS Repeat; Region: RHS_repeat; pfam05593
979556004559	RHS Repeat; Region: RHS_repeat; pfam05593
979556004560	RHS Repeat; Region: RHS_repeat; pfam05593
979556004561	RHS Repeat; Region: RHS_repeat; pfam05593
979556004562	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
979556004563	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
979556004564	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH6; cd08260
979556004565	putative NAD(P) binding site [chemical binding]; other site
979556004566	catalytic Zn binding site [ion binding]; other site
979556004567	structural Zn binding site [ion binding]; other site
979556004568	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
979556004569	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
979556004570	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
979556004571	active site
979556004572	metal binding site [ion binding]; metal-binding site
979556004573	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
979556004574	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
979556004575	active site
979556004576	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556004577	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
979556004578	adenylosuccinate lyase; Provisional; Region: PRK09285
979556004579	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
979556004580	tetramer interface [polypeptide binding]; other site
979556004581	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
979556004582	Low molecular weight phosphatase family; Region: LMWPc; cd00115
979556004583	active site
979556004584	Membrane protein of unknown function; Region: DUF360; pfam04020
979556004585	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
979556004586	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556004587	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556004588	homodimer interface [polypeptide binding]; other site
979556004589	catalytic residue [active]
979556004590	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
979556004591	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
979556004592	tetramer interface [polypeptide binding]; other site
979556004593	TPP-binding site [chemical binding]; other site
979556004594	heterodimer interface [polypeptide binding]; other site
979556004595	phosphorylation loop region [posttranslational modification]
979556004596	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
979556004597	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
979556004598	alpha subunit interface [polypeptide binding]; other site
979556004599	TPP binding site [chemical binding]; other site
979556004600	heterodimer interface [polypeptide binding]; other site
979556004601	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
979556004602	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
979556004603	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
979556004604	E3 interaction surface; other site
979556004605	lipoyl attachment site [posttranslational modification]; other site
979556004606	e3 binding domain; Region: E3_binding; pfam02817
979556004607	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
979556004608	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556004609	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004610	NAD(P) binding site [chemical binding]; other site
979556004611	active site
979556004612	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556004613	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556004614	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
979556004615	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556004616	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004617	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556004618	DNA binding site [nucleotide binding]
979556004619	domain linker motif; other site
979556004620	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556004621	dimerization interface [polypeptide binding]; other site
979556004622	ligand binding site [chemical binding]; other site
979556004623	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556004624	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
979556004625	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
979556004626	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556004627	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004628	dimer interface [polypeptide binding]; other site
979556004629	putative PBP binding loops; other site
979556004630	ABC-ATPase subunit interface; other site
979556004631	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556004632	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004633	dimer interface [polypeptide binding]; other site
979556004634	conserved gate region; other site
979556004635	ABC-ATPase subunit interface; other site
979556004636	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
979556004637	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
979556004638	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
979556004639	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
979556004640	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
979556004641	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
979556004642	Walker A/P-loop; other site
979556004643	ATP binding site [chemical binding]; other site
979556004644	Q-loop/lid; other site
979556004645	ABC transporter signature motif; other site
979556004646	Walker B; other site
979556004647	D-loop; other site
979556004648	H-loop/switch region; other site
979556004649	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
979556004650	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
979556004651	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
979556004652	intersubunit interface [polypeptide binding]; other site
979556004653	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
979556004654	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
979556004655	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
979556004656	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
979556004657	dimer interface [polypeptide binding]; other site
979556004658	putative PBP binding regions; other site
979556004659	ABC-ATPase subunit  interface; other site
979556004660	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
979556004661	metal binding site 2 [ion binding]; metal-binding site
979556004662	putative DNA binding helix; other site
979556004663	metal binding site 1 [ion binding]; metal-binding site
979556004664	dimer interface [polypeptide binding]; other site
979556004665	structural Zn2+ binding site [ion binding]; other site
979556004666	Predicted permeases [General function prediction only]; Region: COG0701
979556004667	Domain of unknown function (DUF1980); Region: DUF1980; cl01492
979556004668	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
979556004669	active site
979556004670	DNA binding site [nucleotide binding]
979556004671	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
979556004672	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
979556004673	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
979556004674	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556004675	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556004676	DNA binding residues [nucleotide binding]
979556004677	dimerization interface [polypeptide binding]; other site
979556004678	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
979556004679	IHF dimer interface [polypeptide binding]; other site
979556004680	IHF - DNA interface [nucleotide binding]; other site
979556004681	Copper resistance protein D; Region: CopD; pfam05425
979556004682	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
979556004683	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
979556004684	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
979556004685	Abi-like protein; Region: Abi_2; cl01988
979556004686	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
979556004687	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
979556004688	DNA binding residues [nucleotide binding]
979556004689	dimer interface [polypeptide binding]; other site
979556004690	PIF1-like helicase; Region: PIF1; pfam05970
979556004691	AAA domain; Region: AAA_30; pfam13604
979556004692	Helicase; Region: Herpes_Helicase; pfam02689
979556004693	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cd00232
979556004694	heme binding pocket [chemical binding]; other site
979556004695	heme ligand [chemical binding]; other site
979556004696	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556004697	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556004698	Threonine/homoserine efflux transporter [Amino acid transport and metabolism]; Region: rhtA; COG5006
979556004699	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
979556004700	Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830
979556004701	oligomer interface [polypeptide binding]; other site
979556004702	metal binding site [ion binding]; metal-binding site
979556004703	metal binding site [ion binding]; metal-binding site
979556004704	putative Cl binding site [ion binding]; other site
979556004705	basic sphincter; other site
979556004706	hydrophobic gate; other site
979556004707	periplasmic entrance; other site
979556004708	L-asparagine permease; Provisional; Region: PRK15049
979556004709	hypothetical protein; Provisional; Region: PRK07236
979556004710	4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243
979556004711	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556004712	Transcriptional regulator [Transcription]; Region: IclR; COG1414
979556004713	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
979556004714	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556004715	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
979556004716	protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422
979556004717	active site
979556004718	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
979556004719	active site
979556004720	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
979556004721	tetramer interface [polypeptide binding]; other site
979556004722	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
979556004723	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
979556004724	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
979556004725	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556004726	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556004727	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
979556004728	hypothetical protein; Provisional; Region: PRK06847
979556004729	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556004730	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556004731	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
979556004732	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556004733	Transcriptional regulator [Transcription]; Region: LysR; COG0583
979556004734	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556004735	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
979556004736	dimerization interface [polypeptide binding]; other site
979556004737	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
979556004738	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
979556004739	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
979556004740	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
979556004741	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
979556004742	active site
979556004743	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556004744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004745	dimer interface [polypeptide binding]; other site
979556004746	conserved gate region; other site
979556004747	ABC-ATPase subunit interface; other site
979556004748	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556004749	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556004750	dimer interface [polypeptide binding]; other site
979556004751	conserved gate region; other site
979556004752	putative PBP binding loops; other site
979556004753	ABC-ATPase subunit interface; other site
979556004754	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
979556004755	pyranose oxidase; Region: pyranose_ox; TIGR02462
979556004756	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
979556004757	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
979556004758	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556004759	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
979556004760	SnoaL-like domain; Region: SnoaL_4; pfam13577
979556004761	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556004762	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556004763	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556004764	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556004765	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
979556004766	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
979556004767	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556004768	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556004769	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556004770	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
979556004771	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
979556004772	putative acetyltransferase; Provisional; Region: PRK03624
979556004773	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556004774	Coenzyme A binding pocket [chemical binding]; other site
979556004775	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
979556004776	ent-kaurene oxidase; Region: PLN02655
979556004777	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556004778	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
979556004779	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
979556004780	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556004781	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556004782	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556004783	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556004784	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
979556004785	catechol 2,3 dioxygenase; Region: catechol_2_3; TIGR03211
979556004786	active site
979556004787	metal binding site [ion binding]; metal-binding site
979556004788	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
979556004789	active site
979556004790	metal binding site [ion binding]; metal-binding site
979556004791	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
979556004792	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556004793	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556004794	Putative cyclase; Region: Cyclase; pfam04199
979556004795	hypothetical protein; Provisional; Region: PRK06847
979556004796	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556004797	Amidohydrolase; Region: Amidohydro_2; pfam04909
979556004798	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
979556004799	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556004800	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556004801	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556004802	classical (c) SDRs; Region: SDR_c; cd05233
979556004803	NAD(P) binding site [chemical binding]; other site
979556004804	active site
979556004805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556004806	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556004807	putative substrate translocation pore; other site
979556004808	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556004809	pyranose oxidase; Region: pyranose_ox; TIGR02462
979556004810	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
979556004811	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
979556004812	Sensors of blue-light using FAD; Region: BLUF; pfam04940
979556004813	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556004814	MarR family; Region: MarR; pfam01047
979556004815	MarR family; Region: MarR_2; cl17246
979556004816	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556004817	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
979556004818	putative NAD(P) binding site [chemical binding]; other site
979556004819	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556004820	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556004821	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556004822	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
979556004823	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556004824	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556004825	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
979556004826	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
979556004827	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
979556004828	trimer interface [polypeptide binding]; other site
979556004829	active site
979556004830	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556004831	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
979556004832	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
979556004833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556004834	helicase 45; Provisional; Region: PTZ00424
979556004835	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
979556004836	ATP binding site [chemical binding]; other site
979556004837	Mg++ binding site [ion binding]; other site
979556004838	motif III; other site
979556004839	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556004840	nucleotide binding region [chemical binding]; other site
979556004841	ATP-binding site [chemical binding]; other site
979556004842	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
979556004843	putative RNA binding site [nucleotide binding]; other site
979556004844	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
979556004845	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556004846	nucleotide binding site [chemical binding]; other site
979556004847	GrpE; Region: GrpE; pfam01025
979556004848	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
979556004849	dimer interface [polypeptide binding]; other site
979556004850	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
979556004851	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
979556004852	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
979556004853	HSP70 interaction site [polypeptide binding]; other site
979556004854	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
979556004855	substrate binding site [polypeptide binding]; other site
979556004856	dimer interface [polypeptide binding]; other site
979556004857	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
979556004858	DNA binding residues [nucleotide binding]
979556004859	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556004860	Transcriptional regulator [Transcription]; Region: IclR; COG1414
979556004861	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556004862	urocanate hydratase; Provisional; Region: PRK05414
979556004863	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
979556004864	allantoate amidohydrolase; Reviewed; Region: PRK09290
979556004865	active site
979556004866	metal binding site [ion binding]; metal-binding site
979556004867	dimer interface [polypeptide binding]; other site
979556004868	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
979556004869	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556004870	active site
979556004871	imidazolonepropionase; Provisional; Region: PRK14085
979556004872	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556004873	active site
979556004874	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556004875	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556004876	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556004877	Walker A/P-loop; other site
979556004878	ATP binding site [chemical binding]; other site
979556004879	Q-loop/lid; other site
979556004880	ABC transporter signature motif; other site
979556004881	Walker B; other site
979556004882	D-loop; other site
979556004883	H-loop/switch region; other site
979556004884	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556004885	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556004886	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
979556004887	Walker A/P-loop; other site
979556004888	ATP binding site [chemical binding]; other site
979556004889	Q-loop/lid; other site
979556004890	ABC transporter signature motif; other site
979556004891	Walker B; other site
979556004892	D-loop; other site
979556004893	H-loop/switch region; other site
979556004894	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
979556004895	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556004896	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
979556004897	FAD binding domain; Region: FAD_binding_4; pfam01565
979556004898	Predicted transcriptional regulators [Transcription]; Region: COG1733
979556004899	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
979556004900	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556004901	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556004902	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556004903	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556004904	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556004905	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
979556004906	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
979556004907	conserved cys residue [active]
979556004908	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556004909	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556004910	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556004911	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
979556004912	Walker A motif; other site
979556004913	ATP binding site [chemical binding]; other site
979556004914	Walker B motif; other site
979556004915	arginine finger; other site
979556004916	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556004917	Walker A motif; other site
979556004918	ATP binding site [chemical binding]; other site
979556004919	Walker B motif; other site
979556004920	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
979556004921	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
979556004922	putative active site [active]
979556004923	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556004924	non-specific DNA binding site [nucleotide binding]; other site
979556004925	salt bridge; other site
979556004926	sequence-specific DNA binding site [nucleotide binding]; other site
979556004927	HipA N-terminal domain; Region: Couple_hipA; cl11853
979556004928	HipA-like N-terminal domain; Region: HipA_N; pfam07805
979556004929	HipA-like C-terminal domain; Region: HipA_C; pfam07804
979556004930	Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138
979556004931	putative FMN binding site [chemical binding]; other site
979556004932	glucose-6-phosphate 1-dehydrogenase; Provisional; Region: PRK12853
979556004933	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
979556004934	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
979556004935	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
979556004936	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
979556004937	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
979556004938	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556004939	active site
979556004940	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
979556004941	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
979556004942	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556004943	Walker A/P-loop; other site
979556004944	ATP binding site [chemical binding]; other site
979556004945	Q-loop/lid; other site
979556004946	ABC transporter signature motif; other site
979556004947	Walker B; other site
979556004948	D-loop; other site
979556004949	H-loop/switch region; other site
979556004950	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
979556004951	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556004952	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556004953	active site
979556004954	phosphorylation site [posttranslational modification]
979556004955	intermolecular recognition site; other site
979556004956	dimerization interface [polypeptide binding]; other site
979556004957	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556004958	DNA binding residues [nucleotide binding]
979556004959	dimerization interface [polypeptide binding]; other site
979556004960	Histidine kinase; Region: HisKA_3; pfam07730
979556004961	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556004962	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
979556004963	ATP binding site [chemical binding]; other site
979556004964	Mg2+ binding site [ion binding]; other site
979556004965	G-X-G motif; other site
979556004966	Predicted flavoprotein [General function prediction only]; Region: COG0431
979556004967	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
979556004968	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556004969	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556004970	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
979556004971	YCII-related domain; Region: YCII; cl00999
979556004972	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
979556004973	putative catalytic site [active]
979556004974	putative phosphate binding site [ion binding]; other site
979556004975	active site
979556004976	metal binding site A [ion binding]; metal-binding site
979556004977	DNA binding site [nucleotide binding]
979556004978	putative AP binding site [nucleotide binding]; other site
979556004979	putative metal binding site B [ion binding]; other site
979556004980	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556004981	active site
979556004982	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556004983	UMP phosphatase; Provisional; Region: PRK10444
979556004984	active site
979556004985	motif I; other site
979556004986	motif II; other site
979556004987	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556004988	CsbD-like; Region: CsbD; pfam05532
979556004989	short chain dehydrogenase; Provisional; Region: PRK06197
979556004990	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556004991	NAD(P) binding site [chemical binding]; other site
979556004992	active site
979556004993	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
979556004994	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
979556004995	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556004996	motif II; other site
979556004997	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
979556004998	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
979556004999	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
979556005000	FeoA domain; Region: FeoA; pfam04023
979556005001	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
979556005002	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
979556005003	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
979556005004	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
979556005005	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
979556005006	putative efflux protein, MATE family; Region: matE; TIGR00797
979556005007	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
979556005008	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
979556005009	active site
979556005010	Zn binding site [ion binding]; other site
979556005011	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
979556005012	H+ Antiporter protein; Region: 2A0121; TIGR00900
979556005013	helix_turn_helix, Arsenical Resistance Operon Repressor; Region: HTH_ARSR; smart00418
979556005014	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005015	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
979556005016	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005018	dimer interface [polypeptide binding]; other site
979556005019	conserved gate region; other site
979556005020	putative PBP binding loops; other site
979556005021	ABC-ATPase subunit interface; other site
979556005022	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
979556005023	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
979556005024	active site pocket [active]
979556005025	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556005026	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556005027	DNA-binding site [nucleotide binding]; DNA binding site
979556005028	FCD domain; Region: FCD; pfam07729
979556005029	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
979556005030	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556005031	enoyl_reductase_like; Region: enoyl_reductase_like; cd08249
979556005032	NAD(P) binding site [chemical binding]; other site
979556005033	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
979556005034	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
979556005035	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
979556005036	putative active site [active]
979556005037	putative substrate binding site [chemical binding]; other site
979556005038	putative cosubstrate binding site; other site
979556005039	catalytic site [active]
979556005040	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
979556005041	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005042	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005043	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556005044	putative substrate translocation pore; other site
979556005045	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556005046	Coenzyme A binding pocket [chemical binding]; other site
979556005047	oxidoreductase; Provisional; Region: PRK12743
979556005048	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005049	NAD(P) binding site [chemical binding]; other site
979556005050	active site
979556005051	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
979556005052	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
979556005053	active site
979556005054	octamer interface [polypeptide binding]; other site
979556005055	glycyl-tRNA synthetase; Provisional; Region: PRK04173
979556005056	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
979556005057	motif 1; other site
979556005058	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
979556005059	active site
979556005060	motif 2; other site
979556005061	motif 3; other site
979556005062	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
979556005063	anticodon binding site; other site
979556005064	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
979556005065	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
979556005066	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556005067	Walker A motif; other site
979556005068	ATP binding site [chemical binding]; other site
979556005069	Walker B motif; other site
979556005070	arginine finger; other site
979556005071	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
979556005072	TPR motif; other site
979556005073	binding surface
979556005074	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556005075	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
979556005076	Walker A/P-loop; other site
979556005077	ATP binding site [chemical binding]; other site
979556005078	Q-loop/lid; other site
979556005079	ABC transporter signature motif; other site
979556005080	Walker B; other site
979556005081	D-loop; other site
979556005082	H-loop/switch region; other site
979556005083	ABC-2 type transporter; Region: ABC2_membrane; cl17235
979556005084	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
979556005085	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
979556005086	Predicted ATPase [General function prediction only]; Region: COG3903
979556005087	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
979556005088	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005089	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005090	DNA binding site [nucleotide binding]
979556005091	domain linker motif; other site
979556005092	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005093	ligand binding site [chemical binding]; other site
979556005094	dimerization interface [polypeptide binding]; other site
979556005095	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
979556005096	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
979556005097	Amidase; Region: Amidase; cl11426
979556005098	amidase; Validated; Region: PRK06565
979556005099	Amidase; Region: Amidase; cl11426
979556005100	type VII secretion protein EccCa; Region: T7SS_EccC_a; TIGR03924
979556005101	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
979556005102	type VII secretion protein EccCb; Region: T7SS_EccC_b; TIGR03925
979556005103	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
979556005104	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
979556005105	WXG100 protein secretion system (Wss), protein YukD; Region: YukD; cl17489
979556005106	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
979556005107	phosphopeptide binding site; other site
979556005108	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
979556005109	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
979556005110	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
979556005111	NAD(P) binding pocket [chemical binding]; other site
979556005112	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
979556005113	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
979556005114	substrate binding site [chemical binding]; other site
979556005115	active site
979556005116	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556005117	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
979556005118	Protein of unknown function (DUF1469); Region: DUF1469; pfam07332
979556005119	Protein of unknown function (DUF4239); Region: DUF4239; pfam14023
979556005120	Chlorite dismutase; Region: Chlor_dismutase; cl01280
979556005121	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
979556005122	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
979556005123	domain interfaces; other site
979556005124	active site
979556005125	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
979556005126	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
979556005127	active site
979556005128	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
979556005129	dimer interface [polypeptide binding]; other site
979556005130	active site
979556005131	Schiff base residues; other site
979556005132	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
979556005133	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556005134	inhibitor-cofactor binding pocket; inhibition site
979556005135	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556005136	catalytic residue [active]
979556005137	LPPG:FO 2-phospho-L-lactate transferase; Provisional; Region: PRK13606
979556005138	Uncharacterized protein family UPF0052; Region: UPF0052; pfam01933
979556005139	phosphate binding site [ion binding]; other site
979556005140	dimer interface [polypeptide binding]; other site
979556005141	Homeodomain-like domain; Region: HTH_23; pfam13384
979556005142	Integrase core domain; Region: rve; pfam00665
979556005143	Integrase core domain; Region: rve_3; pfam13683
979556005144	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
979556005145	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556005146	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
979556005147	DNA binding residues [nucleotide binding]
979556005148	Guanylyl transferase CofC like; Region: CofC; cl17472
979556005149	glucose-6-phosphate dehydrogenase (coenzyme-F420); Region: F420_G6P_DH; TIGR03554
979556005150	probable F420-dependent oxidoreductase, MSMEG_4141 family; Region: F420_MSMEG_4141; TIGR03620
979556005151	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556005152	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
979556005153	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
979556005154	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Region: F420_cofG; TIGR03550
979556005155	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
979556005156	FeS/SAM binding site; other site
979556005157	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Region: F420_cofH; TIGR03551
979556005158	hypothetical protein; Provisional; Region: PRK10621
979556005159	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
979556005160	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
979556005161	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
979556005162	Walker A/P-loop; other site
979556005163	ATP binding site [chemical binding]; other site
979556005164	Q-loop/lid; other site
979556005165	ABC transporter signature motif; other site
979556005166	Walker B; other site
979556005167	D-loop; other site
979556005168	H-loop/switch region; other site
979556005169	3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617
979556005170	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556005171	substrate binding site [chemical binding]; other site
979556005172	oxyanion hole (OAH) forming residues; other site
979556005173	trimer interface [polypeptide binding]; other site
979556005174	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
979556005175	LssY C-terminus; Region: LssY_C; pfam14067
979556005176	Amastin surface glycoprotein; Region: Amastin; cl06401
979556005177	DnaJ domain; Region: DnaJ; pfam00226
979556005178	multifunctional hydroxymethylpyrimidine phosphokinase/4-amino-5-aminomethyl-2-methylpyrimidine hydrolase; Provisional; Region: PRK14713
979556005179	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
979556005180	dimer interface [polypeptide binding]; other site
979556005181	substrate binding site [chemical binding]; other site
979556005182	ATP binding site [chemical binding]; other site
979556005183	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
979556005184	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
979556005185	thiamine phosphate binding site [chemical binding]; other site
979556005186	active site
979556005187	pyrophosphate binding site [ion binding]; other site
979556005188	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
979556005189	substrate binding site [chemical binding]; other site
979556005190	multimerization interface [polypeptide binding]; other site
979556005191	ATP binding site [chemical binding]; other site
979556005192	Domain of unknown function (DUF222); Region: DUF222; pfam02720
979556005193	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556005194	active site
979556005195	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556005196	DNA-binding site [nucleotide binding]; DNA binding site
979556005197	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
979556005198	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
979556005199	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
979556005200	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
979556005201	Walker A/P-loop; other site
979556005202	ATP binding site [chemical binding]; other site
979556005203	Q-loop/lid; other site
979556005204	ABC transporter signature motif; other site
979556005205	Walker B; other site
979556005206	D-loop; other site
979556005207	H-loop/switch region; other site
979556005208	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
979556005209	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
979556005210	Walker A/P-loop; other site
979556005211	ATP binding site [chemical binding]; other site
979556005212	Q-loop/lid; other site
979556005213	ABC transporter signature motif; other site
979556005214	Walker B; other site
979556005215	D-loop; other site
979556005216	Cobalt transport protein; Region: CbiQ; cl00463
979556005217	Phosphotransferase enzyme family; Region: APH; pfam01636
979556005218	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
979556005219	active site
979556005220	ATP binding site [chemical binding]; other site
979556005221	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005222	NAD(P) binding site [chemical binding]; other site
979556005223	active site
979556005224	enoyl-CoA hydratase; Provisional; Region: PRK06688
979556005225	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556005226	substrate binding site [chemical binding]; other site
979556005227	oxyanion hole (OAH) forming residues; other site
979556005228	trimer interface [polypeptide binding]; other site
979556005229	short chain dehydrogenase; Provisional; Region: PRK08278
979556005230	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005231	NAD(P) binding site [chemical binding]; other site
979556005232	active site
979556005233	Transcriptional regulators [Transcription]; Region: GntR; COG1802
979556005234	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556005235	DNA-binding site [nucleotide binding]; DNA binding site
979556005236	FCD domain; Region: FCD; pfam07729
979556005237	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556005238	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
979556005239	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
979556005240	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005241	dimer interface [polypeptide binding]; other site
979556005242	conserved gate region; other site
979556005243	putative PBP binding loops; other site
979556005244	ABC-ATPase subunit interface; other site
979556005245	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556005246	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005247	putative PBP binding loops; other site
979556005248	dimer interface [polypeptide binding]; other site
979556005249	ABC-ATPase subunit interface; other site
979556005250	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
979556005251	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556005252	Walker A/P-loop; other site
979556005253	ATP binding site [chemical binding]; other site
979556005254	Q-loop/lid; other site
979556005255	ABC transporter signature motif; other site
979556005256	Walker B; other site
979556005257	D-loop; other site
979556005258	H-loop/switch region; other site
979556005259	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556005260	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556005261	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556005262	Walker A/P-loop; other site
979556005263	ATP binding site [chemical binding]; other site
979556005264	Q-loop/lid; other site
979556005265	ABC transporter signature motif; other site
979556005266	Walker B; other site
979556005267	D-loop; other site
979556005268	H-loop/switch region; other site
979556005269	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556005270	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556005271	substrate binding pocket [chemical binding]; other site
979556005272	catalytic triad [active]
979556005273	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
979556005274	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
979556005275	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556005276	active site
979556005277	motif I; other site
979556005278	motif II; other site
979556005279	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
979556005280	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
979556005281	beta-galactosidase; Region: BGL; TIGR03356
979556005282	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
979556005283	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
979556005284	active site turn [active]
979556005285	phosphorylation site [posttranslational modification]
979556005286	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
979556005287	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
979556005288	HPr interaction site; other site
979556005289	glycerol kinase (GK) interaction site [polypeptide binding]; other site
979556005290	active site
979556005291	phosphorylation site [posttranslational modification]
979556005292	transcriptional antiterminator BglG; Provisional; Region: PRK09772
979556005293	CAT RNA binding domain; Region: CAT_RBD; smart01061
979556005294	PRD domain; Region: PRD; pfam00874
979556005295	PRD domain; Region: PRD; pfam00874
979556005296	HipA N-terminal domain; Region: Couple_hipA; cl11853
979556005297	HipA-like N-terminal domain; Region: HipA_N; pfam07805
979556005298	HipA-like C-terminal domain; Region: HipA_C; pfam07804
979556005299	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556005300	non-specific DNA binding site [nucleotide binding]; other site
979556005301	salt bridge; other site
979556005302	sequence-specific DNA binding site [nucleotide binding]; other site
979556005303	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14459
979556005304	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
979556005305	FeS/SAM binding site; other site
979556005306	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556005307	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556005308	catalytic residue [active]
979556005309	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556005310	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556005311	active site
979556005312	catalytic tetrad [active]
979556005313	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
979556005314	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
979556005315	nudix motif; other site
979556005316	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556005317	2-enoyl thioester reductase (ETR) like proteins, child 2; Region: ETR_like_2; cd08292
979556005318	putative NAD(P) binding site [chemical binding]; other site
979556005319	putative dimer interface [polypeptide binding]; other site
979556005320	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556005321	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005322	hypothetical protein; Provisional; Region: PRK00967
979556005323	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
979556005324	putative acyltransferase; Provisional; Region: PRK05790
979556005325	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556005326	dimer interface [polypeptide binding]; other site
979556005327	active site
979556005328	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E_like proteins; Region: GAT1_Peptidase_E_like; cd03129
979556005329	catalytic triad [active]
979556005330	active site nucleophile [active]
979556005331	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
979556005332	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
979556005333	active site
979556005334	metal binding site [ion binding]; metal-binding site
979556005335	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
979556005336	CCC1-related family of proteins; Region: CCC1_like; cl00278
979556005337	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556005338	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
979556005339	active site
979556005340	enoyl-CoA hydratase; Provisional; Region: PRK05862
979556005341	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556005342	substrate binding site [chemical binding]; other site
979556005343	oxyanion hole (OAH) forming residues; other site
979556005344	trimer interface [polypeptide binding]; other site
979556005345	MarR family; Region: MarR_2; pfam12802
979556005346	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
979556005347	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
979556005348	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
979556005349	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
979556005350	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005351	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
979556005352	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
979556005353	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556005354	acyl-activating enzyme (AAE) consensus motif; other site
979556005355	AMP binding site [chemical binding]; other site
979556005356	active site
979556005357	CoA binding site [chemical binding]; other site
979556005358	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556005359	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
979556005360	dimer interface [polypeptide binding]; other site
979556005361	active site
979556005362	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
979556005363	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
979556005364	Walker A/P-loop; other site
979556005365	ATP binding site [chemical binding]; other site
979556005366	Q-loop/lid; other site
979556005367	ABC transporter signature motif; other site
979556005368	Walker B; other site
979556005369	D-loop; other site
979556005370	H-loop/switch region; other site
979556005371	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
979556005372	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
979556005373	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
979556005374	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556005375	Coenzyme A binding pocket [chemical binding]; other site
979556005376	Protein of unknown function (DUF817); Region: DUF817; pfam05675
979556005377	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
979556005378	active site
979556005379	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
979556005380	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
979556005381	NAD(P) binding site [chemical binding]; other site
979556005382	catalytic residues [active]
979556005383	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
979556005384	Asp-box motif; other site
979556005385	Carbohydrate Binding Module family 35 (CBM35); appended mainly to enzymes that bind alpha-D-galactose (CBM35-Gal), including glycoside hydrolase (GH) families GH31 and GH43; Region: CBM35_galactosidase-like; cd04081
979556005386	Ca binding site [ion binding]; other site
979556005387	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
979556005388	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
979556005389	putative sugar binding sites [chemical binding]; other site
979556005390	Q-X-W motif; other site
979556005391	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005392	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005393	DNA binding site [nucleotide binding]
979556005394	domain linker motif; other site
979556005395	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005396	dimerization interface [polypeptide binding]; other site
979556005397	ligand binding site [chemical binding]; other site
979556005398	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005399	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556005400	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005401	dimer interface [polypeptide binding]; other site
979556005402	conserved gate region; other site
979556005403	putative PBP binding loops; other site
979556005404	ABC-ATPase subunit interface; other site
979556005405	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005406	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005407	dimer interface [polypeptide binding]; other site
979556005408	conserved gate region; other site
979556005409	putative PBP binding loops; other site
979556005410	ABC-ATPase subunit interface; other site
979556005411	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
979556005412	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
979556005413	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
979556005414	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
979556005415	Cupin domain; Region: Cupin_2; cl17218
979556005416	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556005417	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
979556005418	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556005419	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556005420	Walker A/P-loop; other site
979556005421	ATP binding site [chemical binding]; other site
979556005422	Q-loop/lid; other site
979556005423	ABC transporter signature motif; other site
979556005424	Walker B; other site
979556005425	D-loop; other site
979556005426	H-loop/switch region; other site
979556005427	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556005428	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556005429	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556005430	TM-ABC transporter signature motif; other site
979556005431	Predicted kinase [General function prediction only]; Region: COG4857; cl17281
979556005432	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
979556005433	intersubunit interface [polypeptide binding]; other site
979556005434	active site
979556005435	Zn2+ binding site [ion binding]; other site
979556005436	Predicted enolase-phosphatase [Energy production and conversion]; Region: COG4229
979556005437	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556005438	motif II; other site
979556005439	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
979556005440	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
979556005441	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
979556005442	Amidinotransferase; Region: Amidinotransf; cl12043
979556005443	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556005444	ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073
979556005445	inhibitor-cofactor binding pocket; inhibition site
979556005446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556005447	catalytic residue [active]
979556005448	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
979556005449	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
979556005450	Moco binding site; other site
979556005451	metal coordination site [ion binding]; other site
979556005452	short chain dehydrogenase; Provisional; Region: PRK05854
979556005453	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005454	NAD(P) binding site [chemical binding]; other site
979556005455	active site
979556005456	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
979556005457	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556005458	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
979556005459	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556005460	S-adenosylmethionine binding site [chemical binding]; other site
979556005461	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
979556005462	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556005463	active site
979556005464	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
979556005465	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
979556005466	NAD binding site [chemical binding]; other site
979556005467	catalytic Zn binding site [ion binding]; other site
979556005468	structural Zn binding site [ion binding]; other site
979556005469	hypothetical protein; Provisional; Region: PRK06849
979556005470	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556005471	Uncharacterized conserved protein [Function unknown]; Region: COG2308
979556005472	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
979556005473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
979556005474	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
979556005475	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
979556005476	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
979556005477	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
979556005478	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005479	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
979556005480	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005481	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556005482	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556005483	active site
979556005484	catalytic tetrad [active]
979556005485	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005486	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005487	DNA binding site [nucleotide binding]
979556005488	domain linker motif; other site
979556005489	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005490	dimerization interface [polypeptide binding]; other site
979556005491	ligand binding site [chemical binding]; other site
979556005492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005493	putative substrate translocation pore; other site
979556005494	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556005495	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
979556005496	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
979556005497	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
979556005498	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556005499	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
979556005500	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
979556005501	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556005502	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005503	NAD(P) binding site [chemical binding]; other site
979556005504	active site
979556005505	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005506	active site
979556005507	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556005508	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556005509	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
979556005510	active site
979556005511	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
979556005512	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
979556005513	putative sugar binding sites [chemical binding]; other site
979556005514	Q-X-W motif; other site
979556005515	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005516	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005517	DNA binding site [nucleotide binding]
979556005518	domain linker motif; other site
979556005519	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005520	dimerization interface [polypeptide binding]; other site
979556005521	ligand binding site [chemical binding]; other site
979556005522	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556005523	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556005524	Walker A/P-loop; other site
979556005525	ATP binding site [chemical binding]; other site
979556005526	Q-loop/lid; other site
979556005527	ABC transporter signature motif; other site
979556005528	Walker B; other site
979556005529	D-loop; other site
979556005530	H-loop/switch region; other site
979556005531	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556005532	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556005533	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556005534	TM-ABC transporter signature motif; other site
979556005535	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556005536	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556005537	TM-ABC transporter signature motif; other site
979556005538	rhamnose ABC transporter, rhamnose-binding protein; Region: RhaS; TIGR02637
979556005539	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
979556005540	ligand binding site [chemical binding]; other site
979556005541	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005542	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005543	DNA binding site [nucleotide binding]
979556005544	domain linker motif; other site
979556005545	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005546	ligand binding site [chemical binding]; other site
979556005547	dimerization interface [polypeptide binding]; other site
979556005548	Domain of unknown function (DUF718); Region: DUF718; pfam05336
979556005549	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
979556005550	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
979556005551	short chain dehydrogenase; Validated; Region: PRK08324
979556005552	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
979556005553	rhamnulose-1-phosphate aldolase/alcohol dehydrogenase, classical (c) SDRs; Region: R1PA_ADH_SDR_c; cd08943
979556005554	putative NAD(P) binding site [chemical binding]; other site
979556005555	active site
979556005556	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
979556005557	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
979556005558	N- and C-terminal domain interface [polypeptide binding]; other site
979556005559	active site
979556005560	putative catalytic site [active]
979556005561	metal binding site [ion binding]; metal-binding site
979556005562	ATP binding site [chemical binding]; other site
979556005563	carbohydrate binding site [chemical binding]; other site
979556005564	Isopentenyl diphosphate isomerase (BS_ypgA, MTH48 and related proteins) [Coenzyme transport and metabolism]; Region: idi; COG1304
979556005565	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
979556005566	active site
979556005567	substrate binding site [chemical binding]; other site
979556005568	FMN binding site [chemical binding]; other site
979556005569	putative catalytic residues [active]
979556005570	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556005571	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005572	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
979556005573	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556005574	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556005575	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556005576	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
979556005577	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
979556005578	homodimer interface [polypeptide binding]; other site
979556005579	substrate-cofactor binding pocket; other site
979556005580	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556005581	catalytic residue [active]
979556005582	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556005583	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
979556005584	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
979556005585	Active site serine [active]
979556005586	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556005587	classical (c) SDRs; Region: SDR_c; cd05233
979556005588	NAD(P) binding site [chemical binding]; other site
979556005589	active site
979556005590	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
979556005591	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
979556005592	substrate binding site [chemical binding]; other site
979556005593	dimer interface [polypeptide binding]; other site
979556005594	catalytic triad [active]
979556005595	ribose 5-phosphate isomerase; Region: RPI_actino; TIGR02133
979556005596	dihydroxyacetone kinase; Provisional; Region: PRK14479
979556005597	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
979556005598	DAK2 domain; Region: Dak2; pfam02734
979556005599	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
979556005600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005601	putative substrate translocation pore; other site
979556005602	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556005603	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556005604	DNA-binding site [nucleotide binding]; DNA binding site
979556005605	FCD domain; Region: FCD; pfam07729
979556005606	Fic family protein [Function unknown]; Region: COG3177
979556005607	Fic/DOC family; Region: Fic; pfam02661
979556005608	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005609	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005610	DNA binding site [nucleotide binding]
979556005611	domain linker motif; other site
979556005612	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556005613	ligand binding site [chemical binding]; other site
979556005614	dimerization interface (open form) [polypeptide binding]; other site
979556005615	dimerization interface (closed form) [polypeptide binding]; other site
979556005616	Melibiase; Region: Melibiase; pfam02065
979556005617	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005618	dimer interface [polypeptide binding]; other site
979556005619	conserved gate region; other site
979556005620	putative PBP binding loops; other site
979556005621	ABC-ATPase subunit interface; other site
979556005622	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005623	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005624	dimer interface [polypeptide binding]; other site
979556005625	conserved gate region; other site
979556005626	putative PBP binding loops; other site
979556005627	ABC-ATPase subunit interface; other site
979556005628	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005629	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556005630	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
979556005631	putative metal binding site [ion binding]; other site
979556005632	Carbohydrate Binding Module family 35 (CBM35); appended mainly to enzymes that bind alpha-D-galactose (CBM35-Gal), including glycoside hydrolase (GH) families GH31 and GH43; Region: CBM35_galactosidase-like; cd04081
979556005633	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556005634	Coenzyme A binding pocket [chemical binding]; other site
979556005635	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
979556005636	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
979556005637	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
979556005638	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
979556005639	inhibitor binding site; inhibition site
979556005640	active site
979556005641	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556005642	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556005643	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
979556005644	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556005645	PA14 domain; Region: PA14; cl08459
979556005646	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
979556005647	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
979556005648	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556005649	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556005650	Walker A/P-loop; other site
979556005651	ATP binding site [chemical binding]; other site
979556005652	Q-loop/lid; other site
979556005653	ABC transporter signature motif; other site
979556005654	Walker B; other site
979556005655	D-loop; other site
979556005656	H-loop/switch region; other site
979556005657	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556005658	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556005659	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005660	dimer interface [polypeptide binding]; other site
979556005661	conserved gate region; other site
979556005662	putative PBP binding loops; other site
979556005663	ABC-ATPase subunit interface; other site
979556005664	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556005665	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
979556005666	Walker A/P-loop; other site
979556005667	ATP binding site [chemical binding]; other site
979556005668	Q-loop/lid; other site
979556005669	ABC transporter signature motif; other site
979556005670	Walker B; other site
979556005671	D-loop; other site
979556005672	H-loop/switch region; other site
979556005673	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556005674	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556005675	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005676	dimer interface [polypeptide binding]; other site
979556005677	conserved gate region; other site
979556005678	putative PBP binding loops; other site
979556005679	ABC-ATPase subunit interface; other site
979556005680	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556005681	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
979556005682	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556005683	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556005684	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
979556005685	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
979556005686	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
979556005687	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
979556005688	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005689	putative substrate translocation pore; other site
979556005690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005691	H+ Antiporter protein; Region: 2A0121; TIGR00900
979556005692	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556005693	putative substrate translocation pore; other site
979556005694	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556005695	MarR family; Region: MarR; pfam01047
979556005696	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
979556005697	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556005698	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005699	dimer interface [polypeptide binding]; other site
979556005700	conserved gate region; other site
979556005701	putative PBP binding loops; other site
979556005702	ABC-ATPase subunit interface; other site
979556005703	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005704	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005705	dimer interface [polypeptide binding]; other site
979556005706	conserved gate region; other site
979556005707	putative PBP binding loops; other site
979556005708	ABC-ATPase subunit interface; other site
979556005709	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005710	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
979556005711	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
979556005712	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005713	dimerization interface [polypeptide binding]; other site
979556005714	ligand binding site [chemical binding]; other site
979556005715	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
979556005716	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
979556005717	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
979556005718	Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3458
979556005719	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
979556005720	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556005721	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
979556005722	Metal-binding active site; metal-binding site
979556005723	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
979556005724	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556005725	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556005726	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556005727	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
979556005728	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556005729	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556005730	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556005731	Walker A/P-loop; other site
979556005732	ATP binding site [chemical binding]; other site
979556005733	Q-loop/lid; other site
979556005734	ABC transporter signature motif; other site
979556005735	Walker B; other site
979556005736	D-loop; other site
979556005737	H-loop/switch region; other site
979556005738	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556005739	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556005740	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556005741	TM-ABC transporter signature motif; other site
979556005742	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
979556005743	putative DNA binding site [nucleotide binding]; other site
979556005744	putative Zn2+ binding site [ion binding]; other site
979556005745	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556005746	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556005747	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
979556005748	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556005749	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
979556005750	dimerization interface [polypeptide binding]; other site
979556005751	EamA-like transporter family; Region: EamA; pfam00892
979556005752	EamA-like transporter family; Region: EamA; pfam00892
979556005753	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
979556005754	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
979556005755	DNA methylase; Region: N6_N4_Mtase; pfam01555
979556005756	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556005757	probable F420-dependent oxidoreductase, Rv1855c family; Region: F420_Rv1855c; TIGR03560
979556005758	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
979556005759	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556005760	substrate binding pocket [chemical binding]; other site
979556005761	catalytic triad [active]
979556005762	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
979556005763	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
979556005764	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
979556005765	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
979556005766	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
979556005767	nucleotide binding site/active site [active]
979556005768	HIT family signature motif; other site
979556005769	catalytic residue [active]
979556005770	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005771	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005772	DNA binding site [nucleotide binding]
979556005773	domain linker motif; other site
979556005774	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556005775	ligand binding site [chemical binding]; other site
979556005776	dimerization interface (open form) [polypeptide binding]; other site
979556005777	dimerization interface (closed form) [polypeptide binding]; other site
979556005778	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005779	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556005780	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005781	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005782	putative PBP binding loops; other site
979556005783	dimer interface [polypeptide binding]; other site
979556005784	ABC-ATPase subunit interface; other site
979556005785	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
979556005786	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
979556005787	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
979556005788	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
979556005789	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
979556005790	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005791	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005792	DNA binding site [nucleotide binding]
979556005793	domain linker motif; other site
979556005794	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556005795	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005796	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005797	DNA binding site [nucleotide binding]
979556005798	domain linker motif; other site
979556005799	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005800	ligand binding site [chemical binding]; other site
979556005801	dimerization interface [polypeptide binding]; other site
979556005802	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
979556005803	Melibiase; Region: Melibiase; pfam02065
979556005804	PAS fold; Region: PAS_4; pfam08448
979556005805	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556005806	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556005807	dimer interface [polypeptide binding]; other site
979556005808	phosphorylation site [posttranslational modification]
979556005809	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556005810	ATP binding site [chemical binding]; other site
979556005811	Mg2+ binding site [ion binding]; other site
979556005812	G-X-G motif; other site
979556005813	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
979556005814	Beta-galactosidase jelly roll domain; Region: BetaGal_dom4_5; pfam13364
979556005815	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
979556005816	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
979556005817	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005818	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556005819	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005821	dimer interface [polypeptide binding]; other site
979556005822	conserved gate region; other site
979556005823	putative PBP binding loops; other site
979556005824	ABC-ATPase subunit interface; other site
979556005825	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556005826	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005827	dimer interface [polypeptide binding]; other site
979556005828	ABC-ATPase subunit interface; other site
979556005829	putative PBP binding loops; other site
979556005830	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005831	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556005832	DNA binding site [nucleotide binding]
979556005833	domain linker motif; other site
979556005834	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556005835	ligand binding site [chemical binding]; other site
979556005836	dimerization interface (open form) [polypeptide binding]; other site
979556005837	dimerization interface (closed form) [polypeptide binding]; other site
979556005838	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
979556005839	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556005840	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
979556005841	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
979556005842	trimer interface [polypeptide binding]; other site
979556005843	active site
979556005844	substrate binding site [chemical binding]; other site
979556005845	CoA binding site [chemical binding]; other site
979556005846	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
979556005847	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556005848	putative DNA binding site [nucleotide binding]; other site
979556005849	putative Zn2+ binding site [ion binding]; other site
979556005850	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556005851	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556005852	ligand binding site [chemical binding]; other site
979556005853	dimerization interface [polypeptide binding]; other site
979556005854	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
979556005855	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; cl01752
979556005856	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556005857	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556005858	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
979556005859	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005860	dimer interface [polypeptide binding]; other site
979556005861	putative PBP binding loops; other site
979556005862	ABC-ATPase subunit interface; other site
979556005863	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556005864	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556005865	dimer interface [polypeptide binding]; other site
979556005866	conserved gate region; other site
979556005867	putative PBP binding loops; other site
979556005868	ABC-ATPase subunit interface; other site
979556005869	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
979556005870	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556005871	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556005872	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
979556005873	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005874	NAD(P) binding site [chemical binding]; other site
979556005875	active site
979556005876	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
979556005877	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
979556005878	substrate binding site [chemical binding]; other site
979556005879	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556005880	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
979556005881	active site
979556005882	intersubunit interface [polypeptide binding]; other site
979556005883	catalytic residue [active]
979556005884	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
979556005885	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
979556005886	putative NAD(P) binding site [chemical binding]; other site
979556005887	putative substrate binding site [chemical binding]; other site
979556005888	catalytic Zn binding site [ion binding]; other site
979556005889	structural Zn binding site [ion binding]; other site
979556005890	dimer interface [polypeptide binding]; other site
979556005891	phosphoglucomutase; Validated; Region: PRK07564
979556005892	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
979556005893	active site
979556005894	substrate binding site [chemical binding]; other site
979556005895	metal binding site [ion binding]; metal-binding site
979556005896	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556005897	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556005898	DNA binding residues [nucleotide binding]
979556005899	dimerization interface [polypeptide binding]; other site
979556005900	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556005901	ATP binding site [chemical binding]; other site
979556005902	Mg2+ binding site [ion binding]; other site
979556005903	G-X-G motif; other site
979556005904	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
979556005905	active site
979556005906	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
979556005907	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
979556005908	aromatic chitin/cellulose binding site residues [chemical binding]; other site
979556005909	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
979556005910	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
979556005911	Prephenate dehydratase; Region: PDT; pfam00800
979556005912	prephenate dehydratase; Provisional; Region: PRK11898
979556005913	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
979556005914	putative L-Phe binding site [chemical binding]; other site
979556005915	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
979556005916	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556005917	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
979556005918	Asp23 family; Region: Asp23; pfam03780
979556005919	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
979556005920	DNA photolyase; Region: DNA_photolyase; pfam00875
979556005921	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
979556005922	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
979556005923	seryl-tRNA synthetase; Provisional; Region: PRK05431
979556005924	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
979556005925	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
979556005926	dimer interface [polypeptide binding]; other site
979556005927	active site
979556005928	motif 1; other site
979556005929	motif 2; other site
979556005930	motif 3; other site
979556005931	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
979556005932	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556005933	active site
979556005934	motif I; other site
979556005935	motif II; other site
979556005936	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
979556005937	Predicted membrane protein [Function unknown]; Region: COG4325
979556005938	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
979556005939	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
979556005940	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
979556005941	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; pfam03816
979556005942	Restriction endonuclease; Region: Mrr_cat; pfam04471
979556005943	Right handed beta helix region; Region: Beta_helix; pfam13229
979556005944	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
979556005945	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
979556005946	putative sugar binding sites [chemical binding]; other site
979556005947	Q-X-W motif; other site
979556005948	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
979556005949	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
979556005950	putative sugar binding sites [chemical binding]; other site
979556005951	Q-X-W motif; other site
979556005952	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2354
979556005953	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187
979556005954	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556005955	Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929
979556005956	acyl-activating enzyme (AAE) consensus motif; other site
979556005957	acyl-activating enzyme (AAE) consensus motif; other site
979556005958	putative AMP binding site [chemical binding]; other site
979556005959	putative active site [active]
979556005960	putative CoA binding site [chemical binding]; other site
979556005961	CoA binding site [chemical binding]; other site
979556005962	NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.  Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450
979556005963	putative active site [active]
979556005964	putative catalytic site [active]
979556005965	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
979556005966	active site
979556005967	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
979556005968	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556005969	NAD(P) binding site [chemical binding]; other site
979556005970	active site
979556005971	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556005972	MarR family; Region: MarR_2; pfam12802
979556005973	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556005974	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
979556005975	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
979556005976	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
979556005977	iron-sulfur cluster [ion binding]; other site
979556005978	[2Fe-2S] cluster binding site [ion binding]; other site
979556005979	C-terminal catalytic domain of the oxygenase alpha subunit of dicamba O-demethylase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_DMO-like; cd08878
979556005980	alpha subunit interface [polypeptide binding]; other site
979556005981	active site
979556005982	substrate binding site [chemical binding]; other site
979556005983	Fe binding site [ion binding]; other site
979556005984	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
979556005985	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
979556005986	FMN-binding pocket [chemical binding]; other site
979556005987	flavin binding motif; other site
979556005988	phosphate binding motif [ion binding]; other site
979556005989	beta-alpha-beta structure motif; other site
979556005990	NAD binding pocket [chemical binding]; other site
979556005991	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
979556005992	catalytic loop [active]
979556005993	iron binding site [ion binding]; other site
979556005994	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
979556005995	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
979556005996	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
979556005997	putative ligand binding site [chemical binding]; other site
979556005998	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556005999	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556006000	Walker A/P-loop; other site
979556006001	ATP binding site [chemical binding]; other site
979556006002	Q-loop/lid; other site
979556006003	ABC transporter signature motif; other site
979556006004	Walker B; other site
979556006005	D-loop; other site
979556006006	H-loop/switch region; other site
979556006007	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556006008	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556006009	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556006010	TM-ABC transporter signature motif; other site
979556006011	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556006012	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556006013	TM-ABC transporter signature motif; other site
979556006014	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
979556006015	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556006016	Walker A/P-loop; other site
979556006017	ATP binding site [chemical binding]; other site
979556006018	Q-loop/lid; other site
979556006019	ABC transporter signature motif; other site
979556006020	Walker B; other site
979556006021	D-loop; other site
979556006022	H-loop/switch region; other site
979556006023	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556006024	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556006025	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006026	DNA binding site [nucleotide binding]
979556006027	domain linker motif; other site
979556006028	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556006029	ligand binding site [chemical binding]; other site
979556006030	dimerization interface (open form) [polypeptide binding]; other site
979556006031	dimerization interface (closed form) [polypeptide binding]; other site
979556006032	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556006033	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006034	DNA binding site [nucleotide binding]
979556006035	domain linker motif; other site
979556006036	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556006037	dimerization interface [polypeptide binding]; other site
979556006038	ligand binding site [chemical binding]; other site
979556006039	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556006040	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
979556006041	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006042	putative PBP binding loops; other site
979556006043	dimer interface [polypeptide binding]; other site
979556006044	ABC-ATPase subunit interface; other site
979556006045	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006046	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006047	dimer interface [polypeptide binding]; other site
979556006048	conserved gate region; other site
979556006049	putative PBP binding loops; other site
979556006050	ABC-ATPase subunit interface; other site
979556006051	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
979556006052	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
979556006053	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
979556006054	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
979556006055	putative active site [active]
979556006056	putative catalytic site [active]
979556006057	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
979556006058	Citrate transporter; Region: CitMHS; pfam03600
979556006059	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
979556006060	PAS domain; Region: PAS; smart00091
979556006061	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556006062	ATP binding site [chemical binding]; other site
979556006063	Mg2+ binding site [ion binding]; other site
979556006064	G-X-G motif; other site
979556006065	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
979556006066	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556006067	active site
979556006068	phosphorylation site [posttranslational modification]
979556006069	intermolecular recognition site; other site
979556006070	dimerization interface [polypeptide binding]; other site
979556006071	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556006072	putative DNA binding site [nucleotide binding]; other site
979556006073	putative Zn2+ binding site [ion binding]; other site
979556006074	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like; cd11354
979556006075	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
979556006076	active site
979556006077	catalytic site [active]
979556006078	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
979556006079	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556006080	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556006081	active site
979556006082	phosphorylation site [posttranslational modification]
979556006083	intermolecular recognition site; other site
979556006084	dimerization interface [polypeptide binding]; other site
979556006085	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556006086	DNA binding residues [nucleotide binding]
979556006087	Histidine kinase; Region: HisKA_3; pfam07730
979556006088	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
979556006089	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556006090	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556006091	nucleotide binding site [chemical binding]; other site
979556006092	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006093	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556006094	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006095	dimer interface [polypeptide binding]; other site
979556006096	conserved gate region; other site
979556006097	putative PBP binding loops; other site
979556006098	ABC-ATPase subunit interface; other site
979556006099	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006100	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006101	dimer interface [polypeptide binding]; other site
979556006102	conserved gate region; other site
979556006103	putative PBP binding loops; other site
979556006104	ABC-ATPase subunit interface; other site
979556006105	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins; Region: AmyAc_OligoGlu_TS; cd11332
979556006106	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
979556006107	active site
979556006108	catalytic site [active]
979556006109	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
979556006110	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556006111	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006112	DNA binding site [nucleotide binding]
979556006113	domain linker motif; other site
979556006114	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556006115	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006116	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556006117	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
979556006118	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006119	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006120	dimer interface [polypeptide binding]; other site
979556006121	conserved gate region; other site
979556006122	putative PBP binding loops; other site
979556006123	ABC-ATPase subunit interface; other site
979556006124	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
979556006125	active site
979556006126	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
979556006127	Beta-lactamase; Region: Beta-lactamase; pfam00144
979556006128	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556006129	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
979556006130	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
979556006131	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556006132	putative ADP-binding pocket [chemical binding]; other site
979556006133	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556006134	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556006135	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556006136	active site
979556006137	Haloacid Dehalogenase Superfamily Class (subfamily) IIA; Region: HAD-SF-IIA; TIGR01460
979556006138	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556006139	motif II; other site
979556006140	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556006141	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
979556006142	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556006143	RNA binding surface [nucleotide binding]; other site
979556006144	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556006145	S-adenosylmethionine binding site [chemical binding]; other site
979556006146	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
979556006147	ATP-NAD kinase; Region: NAD_kinase; pfam01513
979556006148	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006149	Walker A/P-loop; other site
979556006150	ATP binding site [chemical binding]; other site
979556006151	Q-loop/lid; other site
979556006152	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
979556006153	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
979556006154	ABC transporter signature motif; other site
979556006155	Walker B; other site
979556006156	D-loop; other site
979556006157	H-loop/switch region; other site
979556006158	CTP synthetase; Validated; Region: pyrG; PRK05380
979556006159	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
979556006160	Catalytic site [active]
979556006161	active site
979556006162	UTP binding site [chemical binding]; other site
979556006163	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
979556006164	active site
979556006165	putative oxyanion hole; other site
979556006166	catalytic triad [active]
979556006167	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
979556006168	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
979556006169	dimer interface [polypeptide binding]; other site
979556006170	ADP-ribose binding site [chemical binding]; other site
979556006171	active site
979556006172	nudix motif; other site
979556006173	metal binding site [ion binding]; metal-binding site
979556006174	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
979556006175	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
979556006176	active site
979556006177	DNA binding site [nucleotide binding]
979556006178	Int/Topo IB signature motif; other site
979556006179	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
979556006180	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006181	Walker A/P-loop; other site
979556006182	ATP binding site [chemical binding]; other site
979556006183	ABC transporter signature motif; other site
979556006184	Walker B; other site
979556006185	D-loop; other site
979556006186	H-loop/switch region; other site
979556006187	ABC transporter; Region: ABC_tran_2; pfam12848
979556006188	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556006189	Transcriptional regulator [Transcription]; Region: LysR; COG0583
979556006190	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556006191	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
979556006192	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
979556006193	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556006194	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
979556006195	oxidoreductase; Provisional; Region: PRK06128
979556006196	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556006197	NAD(P) binding site [chemical binding]; other site
979556006198	active site
979556006199	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556006200	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556006201	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
979556006202	Glycosyl transferase 4-like domain; Region: Glyco_trans_4_4; cl17183
979556006203	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
979556006204	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
979556006205	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
979556006206	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
979556006207	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
979556006208	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556006209	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
979556006210	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
979556006211	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556006212	salt bridge; other site
979556006213	non-specific DNA binding site [nucleotide binding]; other site
979556006214	sequence-specific DNA binding site [nucleotide binding]; other site
979556006215	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556006216	FAD-linked oxidoreductase; Region: bact_FAD_ox; TIGR01679
979556006217	FAD binding domain; Region: FAD_binding_4; pfam01565
979556006218	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
979556006219	MarR family; Region: MarR_2; pfam12802
979556006220	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556006221	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556006222	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
979556006223	catalytic residues [active]
979556006224	dimer interface [polypeptide binding]; other site
979556006225	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
979556006226	PGAP1-like protein; Region: PGAP1; pfam07819
979556006227	nucleophilic elbow; other site
979556006228	catalytic triad; other site
979556006229	PIN domain of the Rv0301 toxin of Mycobacterium tuberculosis and other uncharacterized, annotated PilT protein domain proteins; Region: PIN_MtRv0301; cd09882
979556006230	putative active site [active]
979556006231	Uncharacterized protein conserved in bacteria (DUF2191); Region: DUF2191; pfam09957
979556006232	xylose isomerase; Provisional; Region: PRK12677
979556006233	xylose isomerase, Arthrobacter type; Region: xylA_Arthro; TIGR02631
979556006234	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556006235	D-xylulose kinase; Region: XylB; TIGR01312
979556006236	nucleotide binding site [chemical binding]; other site
979556006237	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006238	DNA binding site [nucleotide binding]
979556006239	domain linker motif; other site
979556006240	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556006241	AAA domain; Region: AAA_17; pfam13207
979556006242	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
979556006243	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
979556006244	L-ribulose-5-phosphate 4-epimerase; Validated; Region: PRK06557
979556006245	intersubunit interface [polypeptide binding]; other site
979556006246	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
979556006247	active site
979556006248	Zn2+ binding site [ion binding]; other site
979556006249	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556006250	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
979556006251	nucleotide binding site [chemical binding]; other site
979556006252	L-arabinose isomerase; Provisional; Region: PRK02929
979556006253	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
979556006254	hexamer (dimer of trimers) interface [polypeptide binding]; other site
979556006255	trimer interface [polypeptide binding]; other site
979556006256	substrate binding site [chemical binding]; other site
979556006257	Mn binding site [ion binding]; other site
979556006258	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK03007
979556006259	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
979556006260	Zn2+ binding site [ion binding]; other site
979556006261	Mg2+ binding site [ion binding]; other site
979556006262	Subunit B of Class III Extradiol ring-cleavage dioxygenases; Region: Extradiol_Dioxygenase_3B_like; cl00599
979556006263	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
979556006264	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556006265	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
979556006266	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
979556006267	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
979556006268	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006269	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006270	dimer interface [polypeptide binding]; other site
979556006271	conserved gate region; other site
979556006272	putative PBP binding loops; other site
979556006273	ABC-ATPase subunit interface; other site
979556006274	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006275	dimer interface [polypeptide binding]; other site
979556006276	conserved gate region; other site
979556006277	putative PBP binding loops; other site
979556006278	ABC-ATPase subunit interface; other site
979556006279	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556006280	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006281	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556006282	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006283	DNA binding site [nucleotide binding]
979556006284	domain linker motif; other site
979556006285	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556006286	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
979556006287	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556006288	active site
979556006289	phosphorylation site [posttranslational modification]
979556006290	intermolecular recognition site; other site
979556006291	dimerization interface [polypeptide binding]; other site
979556006292	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556006293	ATP binding site [chemical binding]; other site
979556006294	Mg2+ binding site [ion binding]; other site
979556006295	G-X-G motif; other site
979556006296	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
979556006297	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
979556006298	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
979556006299	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
979556006300	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556006301	MarR family; Region: MarR_2; cl17246
979556006302	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
979556006303	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
979556006304	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556006305	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556006306	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
979556006307	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556006308	NAD(P) binding site [chemical binding]; other site
979556006309	active site
979556006310	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556006311	putative DNA binding site [nucleotide binding]; other site
979556006312	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
979556006313	putative Zn2+ binding site [ion binding]; other site
979556006314	AsnC family; Region: AsnC_trans_reg; pfam01037
979556006315	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
979556006316	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
979556006317	hexamer interface [polypeptide binding]; other site
979556006318	ligand binding site [chemical binding]; other site
979556006319	putative active site [active]
979556006320	NAD(P) binding site [chemical binding]; other site
979556006321	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
979556006322	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556006323	active site
979556006324	phosphorylation site [posttranslational modification]
979556006325	intermolecular recognition site; other site
979556006326	dimerization interface [polypeptide binding]; other site
979556006327	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
979556006328	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
979556006329	putative active site [active]
979556006330	heme pocket [chemical binding]; other site
979556006331	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556006332	ATP binding site [chemical binding]; other site
979556006333	G-X-G motif; other site
979556006334	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
979556006335	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
979556006336	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
979556006337	Domain of unknown function (DUF1992); Region: DUF1992; pfam09350
979556006338	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; pfam09995
979556006339	Domain of unknown function (DUF4383); Region: DUF4383; pfam14325
979556006340	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
979556006341	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
979556006342	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
979556006343	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556006344	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
979556006345	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
979556006346	Chain length determinant protein; Region: Wzz; cl15801
979556006347	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
979556006348	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556006349	Core-2/I-Branching enzyme; Region: Branch; pfam02485
979556006350	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
979556006351	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
979556006352	trimer interface [polypeptide binding]; other site
979556006353	active site
979556006354	substrate binding site [chemical binding]; other site
979556006355	CoA binding site [chemical binding]; other site
979556006356	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
979556006357	GDP-Fucose binding site [chemical binding]; other site
979556006358	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556006359	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556006360	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556006361	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
979556006362	putative metal binding site; other site
979556006363	putative glycosyl transferase; Provisional; Region: PRK10307
979556006364	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
979556006365	GDP-mannose 4,6-dehydratase; Region: PLN02653
979556006366	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
979556006367	NADP-binding site; other site
979556006368	homotetramer interface [polypeptide binding]; other site
979556006369	substrate binding site [chemical binding]; other site
979556006370	homodimer interface [polypeptide binding]; other site
979556006371	active site
979556006372	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
979556006373	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
979556006374	NADP binding site [chemical binding]; other site
979556006375	active site
979556006376	putative substrate binding site [chemical binding]; other site
979556006377	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
979556006378	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
979556006379	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
979556006380	active site
979556006381	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
979556006382	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
979556006383	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
979556006384	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556006385	MarR family; Region: MarR_2; pfam12802
979556006386	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556006387	catalytic core [active]
979556006388	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556006389	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556006390	DNA binding residues [nucleotide binding]
979556006391	dimerization interface [polypeptide binding]; other site
979556006392	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
979556006393	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556006394	NADH(P)-binding; Region: NAD_binding_10; pfam13460
979556006395	NAD(P) binding site [chemical binding]; other site
979556006396	active site
979556006397	Protein of unknown function (DUF2510); Region: DUF2510; pfam10708
979556006398	Excalibur calcium-binding domain; Region: Excalibur; smart00894
979556006399	S-methylmethionine transporter; Provisional; Region: PRK11387
979556006400	Predicted membrane protein (DUF2101); Region: DUF2101; cl01648
979556006401	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556006402	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
979556006403	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
979556006404	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
979556006405	active site residue [active]
979556006406	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
979556006407	active site residue [active]
979556006408	Domain of unknown function (DUF4188); Region: DUF4188; pfam13826
979556006409	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
979556006410	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556006411	DNA binding residues [nucleotide binding]
979556006412	Domain of unknown function (DUF4287); Region: DUF4287; pfam14117
979556006413	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
979556006414	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
979556006415	Archaeal serine proteases [General function prediction only]; Region: COG1750
979556006416	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
979556006417	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
979556006418	FAD binding pocket [chemical binding]; other site
979556006419	FAD binding motif [chemical binding]; other site
979556006420	phosphate binding motif [ion binding]; other site
979556006421	NAD binding pocket [chemical binding]; other site
979556006422	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
979556006423	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
979556006424	intersubunit interface [polypeptide binding]; other site
979556006425	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556006426	ABC-ATPase subunit  interface; other site
979556006427	dimer interface [polypeptide binding]; other site
979556006428	putative PBP binding regions; other site
979556006429	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556006430	ABC-ATPase subunit  interface; other site
979556006431	dimer interface [polypeptide binding]; other site
979556006432	putative PBP binding regions; other site
979556006433	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
979556006434	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
979556006435	Walker A/P-loop; other site
979556006436	ATP binding site [chemical binding]; other site
979556006437	Q-loop/lid; other site
979556006438	ABC transporter signature motif; other site
979556006439	Walker B; other site
979556006440	D-loop; other site
979556006441	H-loop/switch region; other site
979556006442	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
979556006443	FAD binding pocket [chemical binding]; other site
979556006444	FAD binding motif [chemical binding]; other site
979556006445	phosphate binding motif [ion binding]; other site
979556006446	NAD binding pocket [chemical binding]; other site
979556006447	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
979556006448	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
979556006449	minor groove reading motif; other site
979556006450	helix-hairpin-helix signature motif; other site
979556006451	active site
979556006452	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556006453	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556006454	DNA binding site [nucleotide binding]
979556006455	Predicted acetyltransferase [General function prediction only]; Region: COG2388
979556006456	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
979556006457	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
979556006458	active site
979556006459	metal binding site [ion binding]; metal-binding site
979556006460	DNA binding site [nucleotide binding]
979556006461	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
979556006462	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006463	AAA domain; Region: AAA_23; pfam13476
979556006464	Walker A/P-loop; other site
979556006465	ATP binding site [chemical binding]; other site
979556006466	Q-loop/lid; other site
979556006467	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006468	ABC transporter signature motif; other site
979556006469	Walker B; other site
979556006470	D-loop; other site
979556006471	H-loop/switch region; other site
979556006472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556006473	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
979556006474	putative substrate translocation pore; other site
979556006475	nucleosidase; Provisional; Region: PRK05634
979556006476	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
979556006477	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556006478	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556006479	active site
979556006480	catalytic tetrad [active]
979556006481	Domain of unknown function (DUF427); Region: DUF427; pfam04248
979556006482	NAD synthetase; Reviewed; Region: nadE; PRK02628
979556006483	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
979556006484	multimer interface [polypeptide binding]; other site
979556006485	active site
979556006486	catalytic triad [active]
979556006487	protein interface 1 [polypeptide binding]; other site
979556006488	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
979556006489	homodimer interface [polypeptide binding]; other site
979556006490	NAD binding pocket [chemical binding]; other site
979556006491	ATP binding pocket [chemical binding]; other site
979556006492	Mg binding site [ion binding]; other site
979556006493	active-site loop [active]
979556006494	Predicted nuclease (RecB family) [General function prediction only]; Region: COG2251
979556006495	RNase_H superfamily; Region: RNase_H_2; pfam13482
979556006496	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
979556006497	Part of AAA domain; Region: AAA_19; pfam13245
979556006498	AAA domain; Region: AAA_12; pfam13087
979556006499	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556006500	active site
979556006501	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
979556006502	nucleoside/Zn binding site; other site
979556006503	dimer interface [polypeptide binding]; other site
979556006504	catalytic motif [active]
979556006505	probable F420-dependent oxidoreductase, Rv1855c family; Region: F420_Rv1855c; TIGR03560
979556006506	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556006507	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556006508	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556006509	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
979556006510	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
979556006511	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
979556006512	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
979556006513	TrkA-N domain; Region: TrkA_N; pfam02254
979556006514	TrkA-C domain; Region: TrkA_C; pfam02080
979556006515	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
979556006516	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
979556006517	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556006518	dimerization interface [polypeptide binding]; other site
979556006519	putative DNA binding site [nucleotide binding]; other site
979556006520	putative Zn2+ binding site [ion binding]; other site
979556006521	DNA binding domain, excisionase family; Region: excise; TIGR01764
979556006522	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
979556006523	active site residue [active]
979556006524	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
979556006525	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
979556006526	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006527	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
979556006528	Walker A/P-loop; other site
979556006529	ATP binding site [chemical binding]; other site
979556006530	Q-loop/lid; other site
979556006531	ABC transporter signature motif; other site
979556006532	Walker B; other site
979556006533	D-loop; other site
979556006534	H-loop/switch region; other site
979556006535	aspartyl-tRNA synthetase; Provisional; Region: aspC; PRK05159
979556006536	Asp_Lys_Asn_RS_N: N-terminal, anticodon recognition domain of class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop.  Class 2b aaRSs include the homodimeric aspartyl-; Region: Asp_Lys_Asn_RS_N; cd04100
979556006537	Dimer interface [polypeptide binding]; other site
979556006538	anticodon binding site; other site
979556006539	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
979556006540	motif 1; other site
979556006541	dimer interface [polypeptide binding]; other site
979556006542	active site
979556006543	motif 2; other site
979556006544	motif 3; other site
979556006545	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006547	dimer interface [polypeptide binding]; other site
979556006548	conserved gate region; other site
979556006549	putative PBP binding loops; other site
979556006550	ABC-ATPase subunit interface; other site
979556006551	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006552	ABC-ATPase subunit interface; other site
979556006553	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556006554	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006555	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
979556006556	active site
979556006557	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
979556006558	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
979556006559	active site
979556006560	non-prolyl cis peptide bond; other site
979556006561	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
979556006562	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556006563	active site
979556006564	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
979556006565	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
979556006566	NAD binding site [chemical binding]; other site
979556006567	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
979556006568	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
979556006569	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
979556006570	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556006571	catalytic core [active]
979556006572	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
979556006573	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
979556006574	catalytic residues [active]
979556006575	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
979556006576	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
979556006577	ResB-like family; Region: ResB; pfam05140
979556006578	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
979556006579	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
979556006580	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
979556006581	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
979556006582	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
979556006583	MMPL family; Region: MMPL; pfam03176
979556006584	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556006585	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556006586	O-succinylbenzoate synthase; Provisional; Region: PRK02901
979556006587	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
979556006588	active site
979556006589	probable F420-dependent oxidoreductase, MSMEG_2906 family; Region: F420_MSMEG_2906; TIGR03856
979556006590	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556006591	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
979556006592	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556006593	substrate binding site [chemical binding]; other site
979556006594	oxyanion hole (OAH) forming residues; other site
979556006595	trimer interface [polypeptide binding]; other site
979556006596	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556006597	acyl-activating enzyme (AAE) consensus motif; other site
979556006598	AMP binding site [chemical binding]; other site
979556006599	active site
979556006600	CoA binding site [chemical binding]; other site
979556006601	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
979556006602	UbiA prenyltransferase family; Region: UbiA; pfam01040
979556006603	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
979556006604	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
979556006605	dimer interface [polypeptide binding]; other site
979556006606	tetramer interface [polypeptide binding]; other site
979556006607	PYR/PP interface [polypeptide binding]; other site
979556006608	TPP binding site [chemical binding]; other site
979556006609	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
979556006610	TPP-binding site [chemical binding]; other site
979556006611	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
979556006612	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
979556006613	Protein of unknown function (DUF402); Region: DUF402; cl00979
979556006614	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
979556006615	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556006616	S-adenosylmethionine binding site [chemical binding]; other site
979556006617	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
979556006618	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
979556006619	substrate binding pocket [chemical binding]; other site
979556006620	chain length determination region; other site
979556006621	substrate-Mg2+ binding site; other site
979556006622	catalytic residues [active]
979556006623	aspartate-rich region 1; other site
979556006624	active site lid residues [active]
979556006625	aspartate-rich region 2; other site
979556006626	ferredoxin-NADP+ reductase; Region: PLN02852
979556006627	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556006628	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556006629	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006631	dimer interface [polypeptide binding]; other site
979556006632	conserved gate region; other site
979556006633	putative PBP binding loops; other site
979556006634	ABC-ATPase subunit interface; other site
979556006635	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006637	dimer interface [polypeptide binding]; other site
979556006638	conserved gate region; other site
979556006639	ABC-ATPase subunit interface; other site
979556006640	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
979556006641	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
979556006642	Walker A/P-loop; other site
979556006643	ATP binding site [chemical binding]; other site
979556006644	Q-loop/lid; other site
979556006645	ABC transporter signature motif; other site
979556006646	Walker B; other site
979556006647	D-loop; other site
979556006648	H-loop/switch region; other site
979556006649	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
979556006650	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556006651	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
979556006652	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556006653	acyl-activating enzyme (AAE) consensus motif; other site
979556006654	AMP binding site [chemical binding]; other site
979556006655	active site
979556006656	CoA binding site [chemical binding]; other site
979556006657	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
979556006658	active site
979556006659	catalytic triad [active]
979556006660	oxyanion hole [active]
979556006661	Rifampin ADP-ribosyl transferase; Region: Arr-ms; pfam12120
979556006662	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
979556006663	Right handed beta helix region; Region: Beta_helix; pfam13229
979556006664	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
979556006665	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
979556006666	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
979556006667	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
979556006668	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
979556006669	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556006670	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13539
979556006671	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556006672	Walker A/P-loop; other site
979556006673	ATP binding site [chemical binding]; other site
979556006674	Q-loop/lid; other site
979556006675	ABC transporter signature motif; other site
979556006676	Walker B; other site
979556006677	D-loop; other site
979556006678	H-loop/switch region; other site
979556006679	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
979556006680	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
979556006681	ABC-ATPase subunit  interface; other site
979556006682	dimer interface [polypeptide binding]; other site
979556006683	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
979556006684	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
979556006685	intersubunit interface [polypeptide binding]; other site
979556006686	Transcriptional regulator [Transcription]; Region: LysR; COG0583
979556006687	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556006688	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_6; cd08423
979556006689	putative dimerization interface [polypeptide binding]; other site
979556006690	Proline dehydrogenase; Region: Pro_dh; cl03282
979556006691	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
979556006692	NAD(P) binding site [chemical binding]; other site
979556006693	catalytic residues [active]
979556006694	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
979556006695	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
979556006696	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556006697	DNA-binding site [nucleotide binding]; DNA binding site
979556006698	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556006699	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556006700	homodimer interface [polypeptide binding]; other site
979556006701	catalytic residue [active]
979556006702	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
979556006703	AAA domain; Region: AAA_18; pfam13238
979556006704	active site
979556006705	Domain of unknown function (DUF222); Region: DUF222; pfam02720
979556006706	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556006707	active site
979556006708	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
979556006709	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
979556006710	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
979556006711	active site
979556006712	dimerization interface [polypeptide binding]; other site
979556006713	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
979556006714	Peptidase family M23; Region: Peptidase_M23; pfam01551
979556006715	Transcription factor zinc-finger; Region: zf-TFIIB; cl01565
979556006716	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556006717	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556006718	Walker A/P-loop; other site
979556006719	ATP binding site [chemical binding]; other site
979556006720	Q-loop/lid; other site
979556006721	ABC transporter signature motif; other site
979556006722	Walker B; other site
979556006723	D-loop; other site
979556006724	H-loop/switch region; other site
979556006725	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556006726	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556006727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006728	dimer interface [polypeptide binding]; other site
979556006729	ABC-ATPase subunit interface; other site
979556006730	putative PBP binding loops; other site
979556006731	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556006732	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556006733	Walker A/P-loop; other site
979556006734	ATP binding site [chemical binding]; other site
979556006735	Q-loop/lid; other site
979556006736	ABC transporter signature motif; other site
979556006737	Walker B; other site
979556006738	D-loop; other site
979556006739	H-loop/switch region; other site
979556006740	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556006741	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006742	dimer interface [polypeptide binding]; other site
979556006743	conserved gate region; other site
979556006744	putative PBP binding loops; other site
979556006745	ABC-ATPase subunit interface; other site
979556006746	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
979556006747	Amidase; Region: Amidase; cl11426
979556006748	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
979556006749	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
979556006750	Protein of unknown function (DUF3237); Region: DUF3237; cl07905
979556006751	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556006752	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556006753	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12748
979556006754	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556006755	NAD(P) binding site [chemical binding]; other site
979556006756	active site
979556006757	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556006758	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556006759	active site
979556006760	catalytic tetrad [active]
979556006761	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556006762	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556006763	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556006764	DNA binding residues [nucleotide binding]
979556006765	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
979556006766	CoenzymeA binding site [chemical binding]; other site
979556006767	subunit interaction site [polypeptide binding]; other site
979556006768	PHB binding site; other site
979556006769	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556006770	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556006771	putative substrate translocation pore; other site
979556006772	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556006773	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
979556006774	extended (e) SDRs; Region: SDR_e; cd08946
979556006775	NAD(P) binding site [chemical binding]; other site
979556006776	active site
979556006777	substrate binding site [chemical binding]; other site
979556006778	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556006779	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556006780	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
979556006781	DNA binding residues [nucleotide binding]
979556006782	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
979556006783	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
979556006784	NADP binding site [chemical binding]; other site
979556006785	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
979556006786	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
979556006787	dimer interface [polypeptide binding]; other site
979556006788	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556006789	catalytic residue [active]
979556006790	cystathionine gamma-synthase; Provisional; Region: PRK07811
979556006791	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
979556006792	homodimer interface [polypeptide binding]; other site
979556006793	substrate-cofactor binding pocket; other site
979556006794	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556006795	catalytic residue [active]
979556006796	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
979556006797	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
979556006798	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
979556006799	(R)-hydratase [(R)-specific enoyl-CoA hydratase]. Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway.  The structure of the monomer includes a five-strand antiparallel...; Region: R_hydratase_like; cd03441
979556006800	active site
979556006801	catalytic site [active]
979556006802	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
979556006803	active site 2 [active]
979556006804	active site 1 [active]
979556006805	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13903
979556006806	FAD binding domain; Region: FAD_binding_4; pfam01565
979556006807	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
979556006808	aspartate aminotransferase; Provisional; Region: PRK05764
979556006809	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556006810	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556006811	homodimer interface [polypeptide binding]; other site
979556006812	catalytic residue [active]
979556006813	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
979556006814	putative ion selectivity filter; other site
979556006815	putative pore gating glutamate residue; other site
979556006816	AAA domain; Region: AAA_33; pfam13671
979556006817	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
979556006818	active site
979556006819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556006820	D-galactonate transporter; Region: 2A0114; TIGR00893
979556006821	putative substrate translocation pore; other site
979556006822	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
979556006823	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
979556006824	active site
979556006825	intersubunit interface [polypeptide binding]; other site
979556006826	catalytic residue [active]
979556006827	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
979556006828	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556006829	DNA-binding site [nucleotide binding]; DNA binding site
979556006830	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
979556006831	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
979556006832	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
979556006833	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556006834	active site
979556006835	nucleotide binding site [chemical binding]; other site
979556006836	HIGH motif; other site
979556006837	KMSKS motif; other site
979556006838	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
979556006839	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
979556006840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
979556006841	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
979556006842	metal ion-dependent adhesion site (MIDAS); other site
979556006843	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
979556006844	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556006845	AMP binding site [chemical binding]; other site
979556006846	malate synthase A; Region: malate_syn_A; TIGR01344
979556006847	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
979556006848	active site
979556006849	isocitrate lyase; Provisional; Region: PRK15063
979556006850	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
979556006851	tetramer interface [polypeptide binding]; other site
979556006852	active site
979556006853	Mg2+/Mn2+ binding site [ion binding]; other site
979556006854	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556006855	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556006856	non-specific DNA binding site [nucleotide binding]; other site
979556006857	salt bridge; other site
979556006858	sequence-specific DNA binding site [nucleotide binding]; other site
979556006859	Domain of unknown function (DUF955); Region: DUF955; pfam06114
979556006860	Putative lipopolysaccharide-modifying enzyme; Region: CAP10; smart00672
979556006861	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
979556006862	Na binding site [ion binding]; other site
979556006863	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
979556006864	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
979556006865	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
979556006866	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
979556006867	Protein of unknown function (DUF917); Region: DUF917; pfam06032
979556006868	Protein of unknown function (DUF917); Region: DUF917; pfam06032
979556006869	Protein of unknown function (DUF917); Region: DUF917; cl17829
979556006870	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
979556006871	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
979556006872	Putative glucoamylase; Region: Glycoamylase; pfam10091
979556006873	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
979556006874	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556006875	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
979556006876	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556006877	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556006878	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
979556006879	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556006880	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006881	dimer interface [polypeptide binding]; other site
979556006882	conserved gate region; other site
979556006883	putative PBP binding loops; other site
979556006884	ABC-ATPase subunit interface; other site
979556006885	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556006886	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
979556006887	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
979556006888	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556006889	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556006890	DNA binding site [nucleotide binding]
979556006891	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556006892	dimerization interface [polypeptide binding]; other site
979556006893	ligand binding site [chemical binding]; other site
979556006894	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
979556006895	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
979556006896	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
979556006897	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
979556006898	Walker A/P-loop; other site
979556006899	ATP binding site [chemical binding]; other site
979556006900	Q-loop/lid; other site
979556006901	ABC transporter signature motif; other site
979556006902	Walker B; other site
979556006903	D-loop; other site
979556006904	H-loop/switch region; other site
979556006905	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
979556006906	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006907	dimer interface [polypeptide binding]; other site
979556006908	conserved gate region; other site
979556006909	ABC-ATPase subunit interface; other site
979556006910	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
979556006911	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006912	dimer interface [polypeptide binding]; other site
979556006913	conserved gate region; other site
979556006914	ABC-ATPase subunit interface; other site
979556006915	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
979556006916	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
979556006917	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
979556006918	putative active site [active]
979556006919	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
979556006920	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
979556006921	4-aminobutyrate aminotransferase; Provisional; Region: PRK06058
979556006922	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
979556006923	inhibitor-cofactor binding pocket; inhibition site
979556006924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556006925	catalytic residue [active]
979556006926	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556006927	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
979556006928	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
979556006929	Ligand Binding Site [chemical binding]; other site
979556006930	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
979556006931	Ligand Binding Site [chemical binding]; other site
979556006932	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556006933	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
979556006934	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
979556006935	NAD(P) binding site [chemical binding]; other site
979556006936	catalytic residues [active]
979556006937	Tetratricopeptide repeat; Region: TPR_12; pfam13424
979556006938	HSP90 family protein; Provisional; Region: PRK14083
979556006939	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556006940	ATP binding site [chemical binding]; other site
979556006941	Mg2+ binding site [ion binding]; other site
979556006942	G-X-G motif; other site
979556006943	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
979556006944	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
979556006945	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
979556006946	putative homodimer interface [polypeptide binding]; other site
979556006947	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
979556006948	heterodimer interface [polypeptide binding]; other site
979556006949	homodimer interface [polypeptide binding]; other site
979556006950	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
979556006951	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
979556006952	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
979556006953	23S rRNA interface [nucleotide binding]; other site
979556006954	L7/L12 interface [polypeptide binding]; other site
979556006955	putative thiostrepton binding site; other site
979556006956	L25 interface [polypeptide binding]; other site
979556006957	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
979556006958	mRNA/rRNA interface [nucleotide binding]; other site
979556006959	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
979556006960	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
979556006961	substrate binding pocket [chemical binding]; other site
979556006962	membrane-bound complex binding site; other site
979556006963	hinge residues; other site
979556006964	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
979556006965	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556006966	dimer interface [polypeptide binding]; other site
979556006967	conserved gate region; other site
979556006968	putative PBP binding loops; other site
979556006969	ABC-ATPase subunit interface; other site
979556006970	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
979556006971	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
979556006972	Walker A/P-loop; other site
979556006973	ATP binding site [chemical binding]; other site
979556006974	Q-loop/lid; other site
979556006975	ABC transporter signature motif; other site
979556006976	Walker B; other site
979556006977	D-loop; other site
979556006978	H-loop/switch region; other site
979556006979	Nitronate monooxygenase; Region: NMO; pfam03060
979556006980	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
979556006981	FMN binding site [chemical binding]; other site
979556006982	substrate binding site [chemical binding]; other site
979556006983	putative catalytic residue [active]
979556006984	Acylphosphatase; Region: Acylphosphatase; pfam00708
979556006985	Lysine efflux permease [General function prediction only]; Region: COG1279
979556006986	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
979556006987	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556006988	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
979556006989	dimerization interface [polypeptide binding]; other site
979556006990	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556006991	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
979556006992	putative NAD(P) binding site [chemical binding]; other site
979556006993	MarR family; Region: MarR_2; pfam12802
979556006994	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556006995	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
979556006996	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556006997	putative substrate translocation pore; other site
979556006998	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556006999	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
979556007000	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
979556007001	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
979556007002	23S rRNA interface [nucleotide binding]; other site
979556007003	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
979556007004	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
979556007005	core dimer interface [polypeptide binding]; other site
979556007006	peripheral dimer interface [polypeptide binding]; other site
979556007007	L10 interface [polypeptide binding]; other site
979556007008	L11 interface [polypeptide binding]; other site
979556007009	putative EF-Tu interaction site [polypeptide binding]; other site
979556007010	putative EF-G interaction site [polypeptide binding]; other site
979556007011	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
979556007012	generic binding surface II; other site
979556007013	generic binding surface I; other site
979556007014	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
979556007015	putative active site [active]
979556007016	putative catalytic site [active]
979556007017	putative Mg binding site IVb [ion binding]; other site
979556007018	putative phosphate binding site [ion binding]; other site
979556007019	putative DNA binding site [nucleotide binding]; other site
979556007020	putative Mg binding site IVa [ion binding]; other site
979556007021	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
979556007022	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
979556007023	putative active site [active]
979556007024	putative metal binding site [ion binding]; other site
979556007025	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
979556007026	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556007027	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556007028	DNA binding site [nucleotide binding]
979556007029	domain linker motif; other site
979556007030	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556007031	dimerization interface [polypeptide binding]; other site
979556007032	ligand binding site [chemical binding]; other site
979556007033	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556007034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007035	dimer interface [polypeptide binding]; other site
979556007036	conserved gate region; other site
979556007037	putative PBP binding loops; other site
979556007038	ABC-ATPase subunit interface; other site
979556007039	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556007040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007041	dimer interface [polypeptide binding]; other site
979556007042	conserved gate region; other site
979556007043	putative PBP binding loops; other site
979556007044	ABC-ATPase subunit interface; other site
979556007045	Domain of unknown function (DUF305); Region: DUF305; pfam03713
979556007046	Protein of unknown function (DUF3105); Region: DUF3105; pfam11303
979556007047	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556007048	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
979556007049	putative substrate translocation pore; other site
979556007050	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
979556007051	active site
979556007052	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
979556007053	Domain of unknown function DUF87; Region: DUF87; pfam01935
979556007054	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556007055	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556007056	putative substrate translocation pore; other site
979556007057	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
979556007058	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
979556007059	substrate binding pocket [chemical binding]; other site
979556007060	catalytic triad [active]
979556007061	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
979556007062	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
979556007063	putative NAD(P) binding site [chemical binding]; other site
979556007064	putative active site [active]
979556007065	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
979556007066	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
979556007067	MPT binding site; other site
979556007068	trimer interface [polypeptide binding]; other site
979556007069	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
979556007070	MoaE homodimer interface [polypeptide binding]; other site
979556007071	MoaD interaction [polypeptide binding]; other site
979556007072	active site residues [active]
979556007073	Ubiquitin-like proteins; Region: UBQ; cl00155
979556007074	charged pocket; other site
979556007075	hydrophobic patch; other site
979556007076	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
979556007077	trimer interface [polypeptide binding]; other site
979556007078	dimer interface [polypeptide binding]; other site
979556007079	putative active site [active]
979556007080	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
979556007081	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
979556007082	dimer interface [polypeptide binding]; other site
979556007083	putative functional site; other site
979556007084	putative MPT binding site; other site
979556007085	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
979556007086	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
979556007087	ATP binding site [chemical binding]; other site
979556007088	substrate interface [chemical binding]; other site
979556007089	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
979556007090	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
979556007091	FeS/SAM binding site; other site
979556007092	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
979556007093	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
979556007094	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556007095	DNA binding residues [nucleotide binding]
979556007096	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
979556007097	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556007098	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
979556007099	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007100	ABC-ATPase subunit interface; other site
979556007101	putative PBP binding loops; other site
979556007102	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
979556007103	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556007104	Walker A/P-loop; other site
979556007105	ATP binding site [chemical binding]; other site
979556007106	Q-loop/lid; other site
979556007107	ABC transporter signature motif; other site
979556007108	Walker B; other site
979556007109	D-loop; other site
979556007110	thiol reductant ABC exporter, CydC subunit; Region: CydC; TIGR02868
979556007111	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
979556007112	Walker A/P-loop; other site
979556007113	ATP binding site [chemical binding]; other site
979556007114	Q-loop/lid; other site
979556007115	ABC transporter signature motif; other site
979556007116	Walker B; other site
979556007117	D-loop; other site
979556007118	H-loop/switch region; other site
979556007119	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556007120	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
979556007121	Walker A/P-loop; other site
979556007122	ATP binding site [chemical binding]; other site
979556007123	Q-loop/lid; other site
979556007124	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
979556007125	Walker B; other site
979556007126	D-loop; other site
979556007127	H-loop/switch region; other site
979556007128	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
979556007129	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
979556007130	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
979556007131	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
979556007132	Predicted transcriptional regulators [Transcription]; Region: COG1695
979556007133	Transcriptional regulator PadR-like family; Region: PadR; cl17335
979556007134	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
979556007135	metal-binding site [ion binding]
979556007136	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
979556007137	putative homodimer interface [polypeptide binding]; other site
979556007138	putative homotetramer interface [polypeptide binding]; other site
979556007139	putative allosteric switch controlling residues; other site
979556007140	putative metal binding site [ion binding]; other site
979556007141	putative homodimer-homodimer interface [polypeptide binding]; other site
979556007142	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556007143	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556007144	Walker A/P-loop; other site
979556007145	ATP binding site [chemical binding]; other site
979556007146	Q-loop/lid; other site
979556007147	ABC transporter signature motif; other site
979556007148	Walker B; other site
979556007149	D-loop; other site
979556007150	H-loop/switch region; other site
979556007151	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
979556007152	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556007153	Histidine kinase; Region: HisKA_3; pfam07730
979556007154	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556007155	ATP binding site [chemical binding]; other site
979556007156	G-X-G motif; other site
979556007157	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556007158	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556007159	active site
979556007160	phosphorylation site [posttranslational modification]
979556007161	intermolecular recognition site; other site
979556007162	dimerization interface [polypeptide binding]; other site
979556007163	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556007164	DNA binding residues [nucleotide binding]
979556007165	dimerization interface [polypeptide binding]; other site
979556007166	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
979556007167	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
979556007168	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
979556007169	RNA/DNA hybrid binding site [nucleotide binding]; other site
979556007170	active site
979556007171	Predicted membrane protein [Function unknown]; Region: COG4682
979556007172	yiaA/B two helix domain; Region: YiaAB; pfam05360
979556007173	yiaA/B two helix domain; Region: YiaAB; pfam05360
979556007174	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
979556007175	Helix-turn-helix domain; Region: HTH_31; pfam13560
979556007176	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
979556007177	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
979556007178	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
979556007179	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556007180	ATP binding site [chemical binding]; other site
979556007181	putative Mg++ binding site [ion binding]; other site
979556007182	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556007183	nucleotide binding region [chemical binding]; other site
979556007184	ATP-binding site [chemical binding]; other site
979556007185	Domain of unknown function (DUF3516); Region: DUF3516; pfam12029
979556007186	Haemagglutinin; Region: Hemagglutinin; pfam00509
979556007187	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
979556007188	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
979556007189	dimerization interface [polypeptide binding]; other site
979556007190	DPS ferroxidase diiron center [ion binding]; other site
979556007191	ion pore; other site
979556007192	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556007193	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556007194	DNA binding residues [nucleotide binding]
979556007195	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556007196	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556007197	DNA binding residues [nucleotide binding]
979556007198	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
979556007199	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
979556007200	oxidoreductase; Provisional; Region: PRK06128
979556007201	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556007202	NAD(P) binding site [chemical binding]; other site
979556007203	active site
979556007204	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
979556007205	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556007206	TIGR01777 family protein; Region: yfcH
979556007207	NAD(P) binding site [chemical binding]; other site
979556007208	active site
979556007209	CopC domain; Region: CopC; pfam04234
979556007210	Protein of unknown function (DUF461); Region: DUF461; pfam04314
979556007211	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
979556007212	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
979556007213	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
979556007214	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
979556007215	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
979556007216	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556007217	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556007218	active site
979556007219	catalytic tetrad [active]
979556007220	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_8; cd07817
979556007221	putative hydrophobic ligand binding site [chemical binding]; other site
979556007222	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
979556007223	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556007224	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
979556007225	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
979556007226	putative dimer interface [polypeptide binding]; other site
979556007227	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
979556007228	dimanganese center [ion binding]; other site
979556007229	Predicted membrane protein (DUF2231); Region: DUF2231; cl01730
979556007230	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556007231	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
979556007232	NAD(P) binding site [chemical binding]; other site
979556007233	active site
979556007234	short chain dehydrogenase; Provisional; Region: PRK06138
979556007235	classical (c) SDRs; Region: SDR_c; cd05233
979556007236	NAD(P) binding site [chemical binding]; other site
979556007237	active site
979556007238	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556007239	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556007240	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556007241	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
979556007242	substrate binding site [chemical binding]; other site
979556007243	ATP binding site [chemical binding]; other site
979556007244	Entner-Doudoroff aldolase; Region: eda; TIGR01182
979556007245	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
979556007246	active site
979556007247	intersubunit interface [polypeptide binding]; other site
979556007248	catalytic residue [active]
979556007249	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
979556007250	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
979556007251	NADP binding site [chemical binding]; other site
979556007252	homodimer interface [polypeptide binding]; other site
979556007253	active site
979556007254	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
979556007255	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
979556007256	NAD(P) binding site [chemical binding]; other site
979556007257	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
979556007258	CoA-transferase family III; Region: CoA_transf_3; pfam02515
979556007259	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
979556007260	active site 2 [active]
979556007261	active site 1 [active]
979556007262	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556007263	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556007264	DNA binding site [nucleotide binding]
979556007265	domain linker motif; other site
979556007266	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556007267	dimerization interface [polypeptide binding]; other site
979556007268	ligand binding site [chemical binding]; other site
979556007269	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556007270	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556007271	active site
979556007272	catalytic tetrad [active]
979556007273	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
979556007274	Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; Region: rTSbeta_L-fuconate_dehydratase; cd03324
979556007275	putative active site pocket [active]
979556007276	metal binding site [ion binding]; metal-binding site
979556007277	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556007278	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556007279	DNA-binding site [nucleotide binding]; DNA binding site
979556007280	FCD domain; Region: FCD; pfam07729
979556007281	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
979556007282	Amidohydrolase; Region: Amidohydro_2; pfam04909
979556007283	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556007284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007285	dimer interface [polypeptide binding]; other site
979556007286	conserved gate region; other site
979556007287	putative PBP binding loops; other site
979556007288	ABC-ATPase subunit interface; other site
979556007289	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556007290	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007291	dimer interface [polypeptide binding]; other site
979556007292	conserved gate region; other site
979556007293	putative PBP binding loops; other site
979556007294	ABC-ATPase subunit interface; other site
979556007295	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556007296	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556007297	Domain of unknown function (DUF718); Region: DUF718; pfam05336
979556007298	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
979556007299	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556007300	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
979556007301	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
979556007302	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
979556007303	malonyl-CoA binding site [chemical binding]; other site
979556007304	dimer interface [polypeptide binding]; other site
979556007305	active site
979556007306	product binding site; other site
979556007307	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
979556007308	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
979556007309	MarR family; Region: MarR_2; pfam12802
979556007310	Helix-turn-helix domain; Region: HTH_18; pfam12833
979556007311	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
979556007312	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
979556007313	Sulfate transporter family; Region: Sulfate_transp; pfam00916
979556007314	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
979556007315	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
979556007316	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556007317	DNA binding residues [nucleotide binding]
979556007318	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
979556007319	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556007320	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556007321	DNA-binding site [nucleotide binding]; DNA binding site
979556007322	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
979556007323	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
979556007324	amino acid transporter; Region: 2A0306; TIGR00909
979556007325	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
979556007326	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
979556007327	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
979556007328	Protein of unknown function DUF58; Region: DUF58; pfam01882
979556007329	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556007330	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
979556007331	Walker A motif; other site
979556007332	ATP binding site [chemical binding]; other site
979556007333	Walker B motif; other site
979556007334	arginine finger; other site
979556007335	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556007336	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556007337	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
979556007338	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556007339	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556007340	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556007341	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556007342	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007343	dimer interface [polypeptide binding]; other site
979556007344	conserved gate region; other site
979556007345	putative PBP binding loops; other site
979556007346	ABC-ATPase subunit interface; other site
979556007347	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556007348	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007349	dimer interface [polypeptide binding]; other site
979556007350	conserved gate region; other site
979556007351	putative PBP binding loops; other site
979556007352	ABC-ATPase subunit interface; other site
979556007353	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
979556007354	active site
979556007355	catalytic site [active]
979556007356	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
979556007357	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
979556007358	Uncharacterized conserved protein [Function unknown]; Region: COG3379
979556007359	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
979556007360	phosphonatase-like hydrolase; Region: PhnX-like; TIGR03351
979556007361	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556007362	motif II; other site
979556007363	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
979556007364	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556007365	DNA-binding site [nucleotide binding]; DNA binding site
979556007366	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
979556007367	FAD dependent oxidoreductase TIGR03364; Region: HpnW_proposed
979556007368	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556007369	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
979556007370	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556007371	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007372	putative PBP binding loops; other site
979556007373	ABC-ATPase subunit interface; other site
979556007374	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
979556007375	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556007376	Walker A/P-loop; other site
979556007377	ATP binding site [chemical binding]; other site
979556007378	Q-loop/lid; other site
979556007379	ABC transporter signature motif; other site
979556007380	Walker B; other site
979556007381	D-loop; other site
979556007382	H-loop/switch region; other site
979556007383	TOBE domain; Region: TOBE_2; pfam08402
979556007384	tyramine oxidase; Provisional; Region: tynA; PRK11504
979556007385	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
979556007386	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
979556007387	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
979556007388	Amino acid permease; Region: AA_permease_2; pfam13520
979556007389	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
979556007390	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
979556007391	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556007392	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
979556007393	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
979556007394	dimer interface [polypeptide binding]; other site
979556007395	ADP-ribose binding site [chemical binding]; other site
979556007396	active site
979556007397	nudix motif; other site
979556007398	metal binding site [ion binding]; metal-binding site
979556007399	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
979556007400	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
979556007401	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
979556007402	phosphate acetyltransferase; Reviewed; Region: PRK05632
979556007403	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
979556007404	DRTGG domain; Region: DRTGG; pfam07085
979556007405	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
979556007406	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
979556007407	propionate/acetate kinase; Provisional; Region: PRK12379
979556007408	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
979556007409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556007410	motif II; other site
979556007411	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
979556007412	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
979556007413	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
979556007414	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
979556007415	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556007416	Walker A motif; other site
979556007417	ATP binding site [chemical binding]; other site
979556007418	Walker B motif; other site
979556007419	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
979556007420	recombination protein RecR; Reviewed; Region: recR; PRK00076
979556007421	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
979556007422	RecR protein; Region: RecR; pfam02132
979556007423	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
979556007424	putative active site [active]
979556007425	putative metal-binding site [ion binding]; other site
979556007426	tetramer interface [polypeptide binding]; other site
979556007427	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556007428	Catalytic domain of Protein Kinases; Region: PKc; cd00180
979556007429	active site
979556007430	ATP binding site [chemical binding]; other site
979556007431	substrate binding site [chemical binding]; other site
979556007432	activation loop (A-loop); other site
979556007433	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556007434	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
979556007435	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007436	dimer interface [polypeptide binding]; other site
979556007437	conserved gate region; other site
979556007438	putative PBP binding loops; other site
979556007439	ABC-ATPase subunit interface; other site
979556007440	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
979556007441	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007442	dimer interface [polypeptide binding]; other site
979556007443	conserved gate region; other site
979556007444	putative PBP binding loops; other site
979556007445	ABC-ATPase subunit interface; other site
979556007446	PBP superfamily domain; Region: PBP_like_2; cl17296
979556007447	Putative Ig domain; Region: He_PIG; pfam05345
979556007448	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
979556007449	active site
979556007450	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
979556007451	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
979556007452	Walker A/P-loop; other site
979556007453	ATP binding site [chemical binding]; other site
979556007454	Q-loop/lid; other site
979556007455	ABC transporter signature motif; other site
979556007456	Walker B; other site
979556007457	D-loop; other site
979556007458	H-loop/switch region; other site
979556007459	PBP superfamily domain; Region: PBP_like_2; cl17296
979556007460	Uncharacterized conserved protein [Function unknown]; Region: COG2966
979556007461	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
979556007462	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
979556007463	aspartate kinase; Reviewed; Region: PRK06635
979556007464	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
979556007465	putative nucleotide binding site [chemical binding]; other site
979556007466	putative catalytic residues [active]
979556007467	putative Mg ion binding site [ion binding]; other site
979556007468	putative aspartate binding site [chemical binding]; other site
979556007469	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
979556007470	putative allosteric regulatory site; other site
979556007471	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
979556007472	putative allosteric regulatory residue; other site
979556007473	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
979556007474	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
979556007475	malate:quinone oxidoreductase; Validated; Region: PRK05257
979556007476	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
979556007477	thymidine kinase; Provisional; Region: PRK04296
979556007478	UDP-glucose 4-epimerase; Region: PLN02240
979556007479	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
979556007480	NAD binding site [chemical binding]; other site
979556007481	homodimer interface [polypeptide binding]; other site
979556007482	active site
979556007483	substrate binding site [chemical binding]; other site
979556007484	Transcriptional regulators [Transcription]; Region: GntR; COG1802
979556007485	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556007486	DNA-binding site [nucleotide binding]; DNA binding site
979556007487	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
979556007488	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
979556007489	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
979556007490	FAD binding pocket [chemical binding]; other site
979556007491	FAD binding motif [chemical binding]; other site
979556007492	phosphate binding motif [ion binding]; other site
979556007493	NAD binding pocket [chemical binding]; other site
979556007494	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
979556007495	Eukaryotic phosphomannomutase; Region: PMM; cl17107
979556007496	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
979556007497	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
979556007498	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556007499	Coenzyme A transferase; Region: CoA_trans; cl17247
979556007500	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
979556007501	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
979556007502	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556007503	dimer interface [polypeptide binding]; other site
979556007504	active site
979556007505	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
979556007506	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
979556007507	active site
979556007508	metal binding site [ion binding]; metal-binding site
979556007509	Transglycosylase; Region: Transgly; pfam00912
979556007510	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
979556007511	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
979556007512	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556007513	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
979556007514	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
979556007515	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
979556007516	homotrimer interaction site [polypeptide binding]; other site
979556007517	putative active site [active]
979556007518	citrate synthase; Provisional; Region: PRK14033
979556007519	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
979556007520	oxalacetate binding site [chemical binding]; other site
979556007521	citrylCoA binding site [chemical binding]; other site
979556007522	coenzyme A binding site [chemical binding]; other site
979556007523	catalytic triad [active]
979556007524	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
979556007525	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
979556007526	tetramer interface [polypeptide binding]; other site
979556007527	active site
979556007528	Mg2+/Mn2+ binding site [ion binding]; other site
979556007529	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
979556007530	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
979556007531	DNA-binding site [nucleotide binding]; DNA binding site
979556007532	FCD domain; Region: FCD; pfam07729
979556007533	acetyl-CoA synthetase; Provisional; Region: PRK00174
979556007534	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
979556007535	active site
979556007536	CoA binding site [chemical binding]; other site
979556007537	acyl-activating enzyme (AAE) consensus motif; other site
979556007538	AMP binding site [chemical binding]; other site
979556007539	acetate binding site [chemical binding]; other site
979556007540	Type II/IV secretion system protein; Region: T2SE; pfam00437
979556007541	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
979556007542	Walker A motif; other site
979556007543	ATP binding site [chemical binding]; other site
979556007544	Walker B motif; other site
979556007545	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
979556007546	Protein of unknown function (DUF4244); Region: DUF4244; pfam14029
979556007547	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
979556007548	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
979556007549	active site
979556007550	interdomain interaction site; other site
979556007551	putative metal-binding site [ion binding]; other site
979556007552	nucleotide binding site [chemical binding]; other site
979556007553	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
979556007554	domain I; other site
979556007555	DNA binding groove [nucleotide binding]
979556007556	phosphate binding site [ion binding]; other site
979556007557	domain II; other site
979556007558	domain III; other site
979556007559	nucleotide binding site [chemical binding]; other site
979556007560	catalytic site [active]
979556007561	domain IV; other site
979556007562	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
979556007563	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
979556007564	thymidylate kinase; Validated; Region: tmk; PRK00698
979556007565	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
979556007566	TMP-binding site; other site
979556007567	ATP-binding site [chemical binding]; other site
979556007568	DNA polymerase III subunit delta'; Validated; Region: PRK07940
979556007569	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556007570	Walker A motif; other site
979556007571	ATP binding site [chemical binding]; other site
979556007572	Walker B motif; other site
979556007573	arginine finger; other site
979556007574	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
979556007575	TAP-like protein; Region: Abhydrolase_4; pfam08386
979556007576	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
979556007577	intersubunit interface [polypeptide binding]; other site
979556007578	active site
979556007579	catalytic residue [active]
979556007580	MMPL family; Region: MMPL; pfam03176
979556007581	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
979556007582	catalytic triad [active]
979556007583	conserved cis-peptide bond; other site
979556007584	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
979556007585	PAS domain; Region: PAS_9; pfam13426
979556007586	putative active site [active]
979556007587	heme pocket [chemical binding]; other site
979556007588	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556007589	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556007590	phosphorylation site [posttranslational modification]
979556007591	dimer interface [polypeptide binding]; other site
979556007592	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556007593	ATP binding site [chemical binding]; other site
979556007594	Mg2+ binding site [ion binding]; other site
979556007595	G-X-G motif; other site
979556007596	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
979556007597	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
979556007598	Moco binding site; other site
979556007599	metal coordination site [ion binding]; other site
979556007600	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
979556007601	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556007602	dimerization interface [polypeptide binding]; other site
979556007603	putative DNA binding site [nucleotide binding]; other site
979556007604	putative Zn2+ binding site [ion binding]; other site
979556007605	AsnC family; Region: AsnC_trans_reg; pfam01037
979556007606	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556007607	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556007608	DNA binding site [nucleotide binding]
979556007609	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556007610	ligand binding site [chemical binding]; other site
979556007611	dimerization interface [polypeptide binding]; other site
979556007612	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556007613	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
979556007614	MFS/sugar transport protein; Region: MFS_2; pfam13347
979556007615	GPH family sucrose/H+ symporter; Region: GPH_sucrose; TIGR01301
979556007616	CAAX protease self-immunity; Region: Abi; pfam02517
979556007617	FAD binding domain; Region: FAD_binding_3; pfam01494
979556007618	hypothetical protein; Provisional; Region: PRK07236
979556007619	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
979556007620	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556007621	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
979556007622	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
979556007623	active site
979556007624	HIGH motif; other site
979556007625	dimer interface [polypeptide binding]; other site
979556007626	KMSKS motif; other site
979556007627	Ricin-type beta-trefoil; Region: RICIN; smart00458
979556007628	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
979556007629	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556007630	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
979556007631	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
979556007632	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
979556007633	Glycosyl hydrolase family 43; Region: GH43_4; cd08983
979556007634	active site
979556007635	Transcriptional regulators [Transcription]; Region: MarR; COG1846
979556007636	MarR family; Region: MarR_2; pfam12802
979556007637	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556007638	ABC-ATPase subunit  interface; other site
979556007639	dimer interface [polypeptide binding]; other site
979556007640	putative PBP binding regions; other site
979556007641	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
979556007642	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556007643	ABC-ATPase subunit  interface; other site
979556007644	dimer interface [polypeptide binding]; other site
979556007645	putative PBP binding regions; other site
979556007646	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
979556007647	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
979556007648	siderophore binding site; other site
979556007649	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
979556007650	Fasciclin domain; Region: Fasciclin; pfam02469
979556007651	RNA polymerase sigma factor; Provisional; Region: PRK12514
979556007652	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556007653	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556007654	DNA binding residues [nucleotide binding]
979556007655	putative anti-sigmaE protein; Provisional; Region: PRK13920
979556007656	Anti-sigma-K factor rskA; Region: RskA; pfam10099
979556007657	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
979556007658	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
979556007659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556007660	catalytic residue [active]
979556007661	phosphate transporter ATP-binding protein; Provisional; Region: PRK14241
979556007662	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
979556007663	Walker A/P-loop; other site
979556007664	ATP binding site [chemical binding]; other site
979556007665	Q-loop/lid; other site
979556007666	ABC transporter signature motif; other site
979556007667	Walker B; other site
979556007668	D-loop; other site
979556007669	H-loop/switch region; other site
979556007670	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
979556007671	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007672	dimer interface [polypeptide binding]; other site
979556007673	conserved gate region; other site
979556007674	putative PBP binding loops; other site
979556007675	ABC-ATPase subunit interface; other site
979556007676	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
979556007677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556007678	dimer interface [polypeptide binding]; other site
979556007679	conserved gate region; other site
979556007680	putative PBP binding loops; other site
979556007681	ABC-ATPase subunit interface; other site
979556007682	PBP superfamily domain; Region: PBP_like_2; cl17296
979556007683	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556007684	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
979556007685	acyl-activating enzyme (AAE) consensus motif; other site
979556007686	AMP binding site [chemical binding]; other site
979556007687	active site
979556007688	CoA binding site [chemical binding]; other site
979556007689	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
979556007690	non-ribosomal peptide synthetase terminal domain of unknown function; Region: NRPS_term_dom; TIGR02353
979556007691	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
979556007692	putative trimer interface [polypeptide binding]; other site
979556007693	putative CoA binding site [chemical binding]; other site
979556007694	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
979556007695	putative trimer interface [polypeptide binding]; other site
979556007696	putative CoA binding site [chemical binding]; other site
979556007697	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
979556007698	Zn binding site [ion binding]; other site
979556007699	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
979556007700	active site
979556007701	Ap6A binding site [chemical binding]; other site
979556007702	nudix motif; other site
979556007703	metal binding site [ion binding]; metal-binding site
979556007704	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
979556007705	catalytic core [active]
979556007706	polyphosphate kinase; Provisional; Region: PRK05443
979556007707	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
979556007708	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
979556007709	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
979556007710	putative domain interface [polypeptide binding]; other site
979556007711	putative active site [active]
979556007712	catalytic site [active]
979556007713	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
979556007714	putative domain interface [polypeptide binding]; other site
979556007715	putative active site [active]
979556007716	catalytic site [active]
979556007717	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556007718	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556007719	DNA binding site [nucleotide binding]
979556007720	nitrobindin heme-binding domain; Region: nitrobindin; cd07828
979556007721	heme-binding site [chemical binding]; other site
979556007722	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
979556007723	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
979556007724	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
979556007725	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
979556007726	Methyltransferase domain; Region: Methyltransf_18; pfam12847
979556007727	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556007728	catalytic core [active]
979556007729	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556007730	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
979556007731	PhoU domain; Region: PhoU; pfam01895
979556007732	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
979556007733	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556007734	dimer interface [polypeptide binding]; other site
979556007735	phosphorylation site [posttranslational modification]
979556007736	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556007737	ATP binding site [chemical binding]; other site
979556007738	Mg2+ binding site [ion binding]; other site
979556007739	G-X-G motif; other site
979556007740	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556007741	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556007742	active site
979556007743	phosphorylation site [posttranslational modification]
979556007744	intermolecular recognition site; other site
979556007745	dimerization interface [polypeptide binding]; other site
979556007746	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556007747	DNA binding site [nucleotide binding]
979556007748	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
979556007749	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
979556007750	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
979556007751	active site
979556007752	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
979556007753	homotrimer interaction site [polypeptide binding]; other site
979556007754	zinc binding site [ion binding]; other site
979556007755	CDP-binding sites; other site
979556007756	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556007757	Coenzyme A binding pocket [chemical binding]; other site
979556007758	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
979556007759	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556007760	active site
979556007761	HIGH motif; other site
979556007762	nucleotide binding site [chemical binding]; other site
979556007763	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
979556007764	KMSKS motif; other site
979556007765	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
979556007766	tRNA binding surface [nucleotide binding]; other site
979556007767	anticodon binding site; other site
979556007768	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
979556007769	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
979556007770	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
979556007771	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556007772	NADH(P)-binding; Region: NAD_binding_10; pfam13460
979556007773	NAD(P) binding site [chemical binding]; other site
979556007774	active site
979556007775	Domain of unknown function (DUF4032); Region: DUF4032; pfam13224
979556007776	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
979556007777	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
979556007778	Walker A/P-loop; other site
979556007779	ATP binding site [chemical binding]; other site
979556007780	Q-loop/lid; other site
979556007781	ABC transporter signature motif; other site
979556007782	Walker B; other site
979556007783	D-loop; other site
979556007784	H-loop/switch region; other site
979556007785	TOBE domain; Region: TOBE_2; pfam08402
979556007786	Thioredoxin; Region: Thioredoxin_4; cl17273
979556007787	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
979556007788	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
979556007789	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556007790	Vitamin K-dependent gamma-carboxylase; Region: VKG_Carbox; cl02773
979556007791	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
979556007792	active site
979556007793	catalytic triad [active]
979556007794	Alpha amylase catalytic domain found in Amylosucrase; Region: AmyAc_Amylosucrase; cd11324
979556007795	trehalose synthase; Region: treS_nterm; TIGR02456
979556007796	active site
979556007797	catalytic site [active]
979556007798	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556007799	DNA-binding site [nucleotide binding]; DNA binding site
979556007800	Protein of unknown function, DUF606; Region: DUF606; pfam04657
979556007801	Protein of unknown function, DUF606; Region: DUF606; pfam04657
979556007802	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
979556007803	putative FMN binding site [chemical binding]; other site
979556007804	methionine sulfoxide reductase B; Provisional; Region: PRK00222
979556007805	SelR domain; Region: SelR; pfam01641
979556007806	Uncharacterized protein conserved in bacteria (DUF2332); Region: DUF2332; pfam10094
979556007807	Protein of unknown function (DUF3263); Region: DUF3263; pfam11662
979556007808	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
979556007809	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
979556007810	DNA-binding site [nucleotide binding]; DNA binding site
979556007811	RNA-binding motif; other site
979556007812	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
979556007813	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
979556007814	ring oligomerisation interface [polypeptide binding]; other site
979556007815	ATP/Mg binding site [chemical binding]; other site
979556007816	stacking interactions; other site
979556007817	hinge regions; other site
979556007818	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
979556007819	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
979556007820	DNA binding residues [nucleotide binding]
979556007821	drug binding residues [chemical binding]; other site
979556007822	dimer interface [polypeptide binding]; other site
979556007823	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
979556007824	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556007825	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
979556007826	dimerization interface [polypeptide binding]; other site
979556007827	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556007828	dimer interface [polypeptide binding]; other site
979556007829	phosphorylation site [posttranslational modification]
979556007830	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556007831	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556007832	ATP binding site [chemical binding]; other site
979556007833	Mg2+ binding site [ion binding]; other site
979556007834	G-X-G motif; other site
979556007835	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556007836	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556007837	active site
979556007838	phosphorylation site [posttranslational modification]
979556007839	intermolecular recognition site; other site
979556007840	dimerization interface [polypeptide binding]; other site
979556007841	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556007842	DNA binding site [nucleotide binding]
979556007843	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
979556007844	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
979556007845	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
979556007846	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556007847	nucleotide binding region [chemical binding]; other site
979556007848	ATP-binding site [chemical binding]; other site
979556007849	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
979556007850	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
979556007851	DNA-binding site [nucleotide binding]; DNA binding site
979556007852	RNA-binding motif; other site
979556007853	Protein of unknown function (DUF3027); Region: DUF3027; pfam11228
979556007854	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556007855	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556007856	catalytic residue [active]
979556007857	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
979556007858	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
979556007859	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
979556007860	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
979556007861	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
979556007862	Peptidase family M23; Region: Peptidase_M23; pfam01551
979556007863	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
979556007864	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556007865	active site
979556007866	Isochorismatase family; Region: Isochorismatase; pfam00857
979556007867	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
979556007868	catalytic triad [active]
979556007869	conserved cis-peptide bond; other site
979556007870	DNA Polymerase Y-family; Region: PolY_like; cd03468
979556007871	active site
979556007872	DNA binding site [nucleotide binding]
979556007873	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
979556007874	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
979556007875	active site
979556007876	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
979556007877	generic binding surface I; other site
979556007878	generic binding surface II; other site
979556007879	Protein of unknown function (DUF2510); Region: DUF2510; pfam10708
979556007880	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
979556007881	Flavoprotein; Region: Flavoprotein; pfam02441
979556007882	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
979556007883	NRDE protein; Region: NRDE; cl01315
979556007884	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
979556007885	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556007886	dimer interface [polypeptide binding]; other site
979556007887	active site
979556007888	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
979556007889	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556007890	substrate binding site [chemical binding]; other site
979556007891	oxyanion hole (OAH) forming residues; other site
979556007892	trimer interface [polypeptide binding]; other site
979556007893	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
979556007894	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
979556007895	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
979556007896	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
979556007897	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
979556007898	substrate binding site [chemical binding]; other site
979556007899	dimer interface [polypeptide binding]; other site
979556007900	NADP binding site [chemical binding]; other site
979556007901	catalytic residues [active]
979556007902	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
979556007903	active site 2 [active]
979556007904	active site 1 [active]
979556007905	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
979556007906	CoenzymeA binding site [chemical binding]; other site
979556007907	subunit interaction site [polypeptide binding]; other site
979556007908	PHB binding site; other site
979556007909	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
979556007910	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
979556007911	acyl-activating enzyme (AAE) consensus motif; other site
979556007912	AMP binding site [chemical binding]; other site
979556007913	active site
979556007914	CoA binding site [chemical binding]; other site
979556007915	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
979556007916	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
979556007917	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556007918	motif II; other site
979556007919	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
979556007920	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
979556007921	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
979556007922	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
979556007923	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
979556007924	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
979556007925	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
979556007926	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
979556007927	FAD binding pocket [chemical binding]; other site
979556007928	FAD binding motif [chemical binding]; other site
979556007929	phosphate binding motif [ion binding]; other site
979556007930	beta-alpha-beta structure motif; other site
979556007931	NAD(p) ribose binding residues [chemical binding]; other site
979556007932	NAD binding pocket [chemical binding]; other site
979556007933	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
979556007934	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
979556007935	catalytic loop [active]
979556007936	iron binding site [ion binding]; other site
979556007937	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556007938	enoyl-CoA hydratase; Provisional; Region: PRK06688
979556007939	substrate binding site [chemical binding]; other site
979556007940	oxyanion hole (OAH) forming residues; other site
979556007941	trimer interface [polypeptide binding]; other site
979556007942	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
979556007943	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556007944	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556007945	DNA binding residues [nucleotide binding]
979556007946	Protein of unknown function, DUF485; Region: DUF485; pfam04341
979556007947	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
979556007948	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
979556007949	Na binding site [ion binding]; other site
979556007950	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
979556007951	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
979556007952	DNA binding site [nucleotide binding]
979556007953	active site
979556007954	Part of AAA domain; Region: AAA_19; pfam13245
979556007955	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
979556007956	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
979556007957	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
979556007958	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
979556007959	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
979556007960	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
979556007961	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
979556007962	active site
979556007963	tetramer interface; other site
979556007964	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
979556007965	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
979556007966	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
979556007967	dimer interface [polypeptide binding]; other site
979556007968	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556007969	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556007970	V-type ATP synthase subunit I; Validated; Region: PRK05771
979556007971	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
979556007972	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556007973	Walker A/P-loop; other site
979556007974	ATP binding site [chemical binding]; other site
979556007975	Q-loop/lid; other site
979556007976	ABC transporter signature motif; other site
979556007977	Walker B; other site
979556007978	D-loop; other site
979556007979	H-loop/switch region; other site
979556007980	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
979556007981	FtsX-like permease family; Region: FtsX; pfam02687
979556007982	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
979556007983	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
979556007984	Walker A/P-loop; other site
979556007985	ATP binding site [chemical binding]; other site
979556007986	Q-loop/lid; other site
979556007987	ABC transporter signature motif; other site
979556007988	Walker B; other site
979556007989	D-loop; other site
979556007990	H-loop/switch region; other site
979556007991	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
979556007992	amino acid transporter; Region: 2A0306; TIGR00909
979556007993	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
979556007994	Lsr2; Region: Lsr2; pfam11774
979556007995	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; cl01408
979556007996	Lsr2; Region: Lsr2; pfam11774
979556007997	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
979556007998	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
979556007999	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
979556008000	NAD binding site [chemical binding]; other site
979556008001	Phe binding site; other site
979556008002	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
979556008003	putative deacylase active site [active]
979556008004	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
979556008005	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556008006	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008007	dimer interface [polypeptide binding]; other site
979556008008	conserved gate region; other site
979556008009	ABC-ATPase subunit interface; other site
979556008010	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
979556008011	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008012	dimer interface [polypeptide binding]; other site
979556008013	conserved gate region; other site
979556008014	putative PBP binding loops; other site
979556008015	ABC-ATPase subunit interface; other site
979556008016	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556008017	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556008018	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008019	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556008020	DNA binding site [nucleotide binding]
979556008021	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556008022	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556008023	Transcriptional regulator [Transcription]; Region: IclR; COG1414
979556008024	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
979556008025	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556008026	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
979556008027	active sites [active]
979556008028	tetramer interface [polypeptide binding]; other site
979556008029	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556008030	catalytic core [active]
979556008031	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
979556008032	putative active site pocket [active]
979556008033	dimerization interface [polypeptide binding]; other site
979556008034	putative catalytic residue [active]
979556008035	Protein of unknown function (DUF445); Region: DUF445; pfam04286
979556008036	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
979556008037	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
979556008038	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
979556008039	H+ Antiporter protein; Region: 2A0121; TIGR00900
979556008040	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
979556008041	catalytic residues [active]
979556008042	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
979556008043	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
979556008044	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
979556008045	Class I ribonucleotide reductase; Region: RNR_I; cd01679
979556008046	active site
979556008047	dimer interface [polypeptide binding]; other site
979556008048	catalytic residues [active]
979556008049	effector binding site; other site
979556008050	R2 peptide binding site; other site
979556008051	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
979556008052	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
979556008053	dimer interface [polypeptide binding]; other site
979556008054	putative radical transfer pathway; other site
979556008055	diiron center [ion binding]; other site
979556008056	tyrosyl radical; other site
979556008057	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
979556008058	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008059	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556008060	DNA binding site [nucleotide binding]
979556008061	domain linker motif; other site
979556008062	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556008063	ligand binding site [chemical binding]; other site
979556008064	dimerization interface [polypeptide binding]; other site
979556008065	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
979556008066	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556008067	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556008068	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
979556008069	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556008070	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008071	dimer interface [polypeptide binding]; other site
979556008072	conserved gate region; other site
979556008073	putative PBP binding loops; other site
979556008074	ABC-ATPase subunit interface; other site
979556008075	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
979556008076	substrate binding site [chemical binding]; other site
979556008077	catalytic residues [active]
979556008078	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
979556008079	putative metal binding site [ion binding]; other site
979556008080	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
979556008081	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556008082	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
979556008083	Protein of unknown function (DUF993); Region: DUF993; pfam06187
979556008084	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556008085	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
979556008086	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
979556008087	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
979556008088	active site
979556008089	catalytic site [active]
979556008090	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
979556008091	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
979556008092	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556008093	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
979556008094	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
979556008095	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556008096	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008097	dimer interface [polypeptide binding]; other site
979556008098	conserved gate region; other site
979556008099	putative PBP binding loops; other site
979556008100	ABC-ATPase subunit interface; other site
979556008101	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008102	dimer interface [polypeptide binding]; other site
979556008103	conserved gate region; other site
979556008104	ABC-ATPase subunit interface; other site
979556008105	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556008106	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556008107	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_8; cd12167
979556008108	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
979556008109	putative ligand binding site [chemical binding]; other site
979556008110	putative NAD binding site [chemical binding]; other site
979556008111	catalytic site [active]
979556008112	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
979556008113	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
979556008114	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
979556008115	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008116	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556008117	dimerization interface [polypeptide binding]; other site
979556008118	ligand binding site [chemical binding]; other site
979556008119	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
979556008120	MarR family; Region: MarR_2; cl17246
979556008121	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556008122	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
979556008123	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556008124	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
979556008125	substrate binding site [chemical binding]; other site
979556008126	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556008127	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008128	dimer interface [polypeptide binding]; other site
979556008129	conserved gate region; other site
979556008130	putative PBP binding loops; other site
979556008131	ABC-ATPase subunit interface; other site
979556008132	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556008133	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008134	dimer interface [polypeptide binding]; other site
979556008135	conserved gate region; other site
979556008136	putative PBP binding loops; other site
979556008137	ABC-ATPase subunit interface; other site
979556008138	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556008139	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556008140	Walker A/P-loop; other site
979556008141	ATP binding site [chemical binding]; other site
979556008142	Q-loop/lid; other site
979556008143	ABC transporter signature motif; other site
979556008144	Walker B; other site
979556008145	D-loop; other site
979556008146	H-loop/switch region; other site
979556008147	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556008148	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
979556008149	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556008150	Walker A/P-loop; other site
979556008151	ATP binding site [chemical binding]; other site
979556008152	Q-loop/lid; other site
979556008153	ABC transporter signature motif; other site
979556008154	Walker B; other site
979556008155	D-loop; other site
979556008156	H-loop/switch region; other site
979556008157	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556008158	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
979556008159	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
979556008160	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
979556008161	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
979556008162	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
979556008163	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
979556008164	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
979556008165	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
979556008166	Melibiase; Region: Melibiase; pfam02065
979556008167	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
979556008168	active site
979556008169	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
979556008170	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
979556008171	substrate binding site [chemical binding]; other site
979556008172	ATP binding site [chemical binding]; other site
979556008173	SnoaL-like domain; Region: SnoaL_3; pfam13474
979556008174	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
979556008175	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
979556008176	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
979556008177	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
979556008178	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556008179	S-adenosylmethionine binding site [chemical binding]; other site
979556008180	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
979556008181	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
979556008182	dimer interface [polypeptide binding]; other site
979556008183	PYR/PP interface [polypeptide binding]; other site
979556008184	TPP binding site [chemical binding]; other site
979556008185	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
979556008186	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
979556008187	TPP-binding site [chemical binding]; other site
979556008188	dimer interface [polypeptide binding]; other site
979556008189	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
979556008190	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
979556008191	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
979556008192	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556008193	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008194	dimer interface [polypeptide binding]; other site
979556008195	conserved gate region; other site
979556008196	ABC-ATPase subunit interface; other site
979556008197	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
979556008198	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008199	putative PBP binding loops; other site
979556008200	ABC-ATPase subunit interface; other site
979556008201	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
979556008202	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
979556008203	active site
979556008204	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
979556008205	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008206	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556008207	DNA binding site [nucleotide binding]
979556008208	domain linker motif; other site
979556008209	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
979556008210	dimerization interface [polypeptide binding]; other site
979556008211	ligand binding site [chemical binding]; other site
979556008212	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
979556008213	Clp amino terminal domain; Region: Clp_N; pfam02861
979556008214	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556008215	Walker A motif; other site
979556008216	ATP binding site [chemical binding]; other site
979556008217	Walker B motif; other site
979556008218	arginine finger; other site
979556008219	UvrB/uvrC motif; Region: UVR; pfam02151
979556008220	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556008221	Walker A motif; other site
979556008222	ATP binding site [chemical binding]; other site
979556008223	Walker B motif; other site
979556008224	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
979556008225	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
979556008226	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556008227	probable F420-dependent oxidoreductase, MSMEG_4141 family; Region: F420_MSMEG_4141; TIGR03620
979556008228	F420-dependent oxidoreductase, MSMEG_4879 family; Region: F420_MSMEG_4879; TIGR03564
979556008229	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
979556008230	Predicted membrane protein [Function unknown]; Region: COG2311
979556008231	Protein of unknown function (DUF418); Region: DUF418; cl12135
979556008232	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
979556008233	Predicted membrane protein [Function unknown]; Region: COG4270
979556008234	DEAD-like helicases superfamily; Region: DEXDc; smart00487
979556008235	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556008236	ATP binding site [chemical binding]; other site
979556008237	putative Mg++ binding site [ion binding]; other site
979556008238	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556008239	nucleotide binding region [chemical binding]; other site
979556008240	ATP-binding site [chemical binding]; other site
979556008241	Sugar-specific transcriptional regulator TrmB; Region: TrmB; cl17775
979556008242	ATP-dependent DNA ligase; Reviewed; Region: ligB; PRK03180
979556008243	Adenylation domain of archaeal and bacterial LigB-like DNA ligases; Region: Adenylation_DNA_ligase_Arch_LigB; cd07901
979556008244	active site
979556008245	DNA binding site [nucleotide binding]
979556008246	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of archaeal and bacterial ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_Arch_LigB; cd07972
979556008247	DNA binding site [nucleotide binding]
979556008248	Uncharacterized conserved protein [Function unknown]; Region: COG1432
979556008249	NYN domain; Region: NYN; pfam01936
979556008250	putative metal binding site [ion binding]; other site
979556008251	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
979556008252	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
979556008253	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
979556008254	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
979556008255	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
979556008256	metal binding site [ion binding]; metal-binding site
979556008257	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008258	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556008259	DNA binding site [nucleotide binding]
979556008260	domain linker motif; other site
979556008261	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
979556008262	ligand binding site [chemical binding]; other site
979556008263	dimerization interface (open form) [polypeptide binding]; other site
979556008264	dimerization interface (closed form) [polypeptide binding]; other site
979556008265	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
979556008266	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
979556008267	putative ligand binding site [chemical binding]; other site
979556008268	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
979556008269	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
979556008270	Walker A/P-loop; other site
979556008271	ATP binding site [chemical binding]; other site
979556008272	Q-loop/lid; other site
979556008273	ABC transporter signature motif; other site
979556008274	Walker B; other site
979556008275	D-loop; other site
979556008276	H-loop/switch region; other site
979556008277	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
979556008278	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556008279	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
979556008280	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
979556008281	TM-ABC transporter signature motif; other site
979556008282	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556008283	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
979556008284	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
979556008285	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
979556008286	Histidine kinase; Region: HisKA_3; pfam07730
979556008287	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
979556008288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556008289	active site
979556008290	phosphorylation site [posttranslational modification]
979556008291	intermolecular recognition site; other site
979556008292	dimerization interface [polypeptide binding]; other site
979556008293	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
979556008294	DNA binding residues [nucleotide binding]
979556008295	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
979556008296	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556008297	MarR family; Region: MarR_2; cl17246
979556008298	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556008299	ATP binding site [chemical binding]; other site
979556008300	putative Mg++ binding site [ion binding]; other site
979556008301	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556008302	nucleotide binding region [chemical binding]; other site
979556008303	ATP-binding site [chemical binding]; other site
979556008304	Helicase associated domain (HA2); Region: HA2; pfam04408
979556008305	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
979556008306	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
979556008307	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
979556008308	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
979556008309	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
979556008310	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
979556008311	NMT1/THI5 like; Region: NMT1; pfam09084
979556008312	substrate binding pocket [chemical binding]; other site
979556008313	membrane-bound complex binding site; other site
979556008314	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
979556008315	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
979556008316	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
979556008317	Walker A/P-loop; other site
979556008318	ATP binding site [chemical binding]; other site
979556008319	Q-loop/lid; other site
979556008320	ABC transporter signature motif; other site
979556008321	Walker B; other site
979556008322	D-loop; other site
979556008323	H-loop/switch region; other site
979556008324	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556008325	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
979556008326	F420-dependent oxidoreductase, CPS_4043 family; Region: F420_CPS_4043; TIGR03842
979556008327	phenylhydantoinase; Validated; Region: PRK08323
979556008328	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
979556008329	tetramer interface [polypeptide binding]; other site
979556008330	active site
979556008331	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
979556008332	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
979556008333	active site
979556008334	catalytic triad [active]
979556008335	dimer interface [polypeptide binding]; other site
979556008336	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
979556008337	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556008338	DNA-binding site [nucleotide binding]; DNA binding site
979556008339	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556008340	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556008341	homodimer interface [polypeptide binding]; other site
979556008342	catalytic residue [active]
979556008343	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556008344	active site
979556008345	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556008346	catalytic tetrad [active]
979556008347	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
979556008348	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
979556008349	catalytic residues [active]
979556008350	Predicted ATPase [General function prediction only]; Region: COG3910
979556008351	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556008352	Walker A/P-loop; other site
979556008353	ATP binding site [chemical binding]; other site
979556008354	Q-loop/lid; other site
979556008355	ABC transporter signature motif; other site
979556008356	Walker B; other site
979556008357	D-loop; other site
979556008358	H-loop/switch region; other site
979556008359	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
979556008360	Predicted methyltransferases [General function prediction only]; Region: COG0313
979556008361	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
979556008362	putative SAM binding site [chemical binding]; other site
979556008363	putative homodimer interface [polypeptide binding]; other site
979556008364	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
979556008365	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
979556008366	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
979556008367	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008368	dimer interface [polypeptide binding]; other site
979556008369	conserved gate region; other site
979556008370	putative PBP binding loops; other site
979556008371	ABC-ATPase subunit interface; other site
979556008372	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008373	dimer interface [polypeptide binding]; other site
979556008374	conserved gate region; other site
979556008375	putative PBP binding loops; other site
979556008376	ABC-ATPase subunit interface; other site
979556008377	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
979556008378	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
979556008379	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
979556008380	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
979556008381	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
979556008382	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
979556008383	Transcriptional regulators [Transcription]; Region: PurR; COG1609
979556008384	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
979556008385	DNA binding site [nucleotide binding]
979556008386	domain linker motif; other site
979556008387	Ligand binding domain of a transcription regulator of cellulose genes, CelR, which is highly homologous to the LacI-GalR family of bacterial transcription regulators; Region: PBP1_CelR; cd06295
979556008388	putative dimerization interface [polypeptide binding]; other site
979556008389	putative ligand binding site [chemical binding]; other site
979556008390	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
979556008391	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
979556008392	active site
979556008393	HIGH motif; other site
979556008394	KMSKS motif; other site
979556008395	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
979556008396	tRNA binding surface [nucleotide binding]; other site
979556008397	anticodon binding site; other site
979556008398	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
979556008399	active site
979556008400	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
979556008401	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008402	putative substrate translocation pore; other site
979556008403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008404	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
979556008405	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556008406	S-adenosylmethionine binding site [chemical binding]; other site
979556008407	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
979556008408	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
979556008409	active site
979556008410	metal binding site [ion binding]; metal-binding site
979556008411	hexamer interface [polypeptide binding]; other site
979556008412	Protein of unknown function (DUF3184); Region: DUF3184; pfam11380
979556008413	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
979556008414	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
979556008415	active site
979556008416	catalytic tetrad [active]
979556008417	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK03188
979556008418	Domain of unknown function (DUF427); Region: DUF427; pfam04248
979556008419	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
979556008420	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556008421	Walker A/P-loop; other site
979556008422	ATP binding site [chemical binding]; other site
979556008423	Q-loop/lid; other site
979556008424	ABC transporter signature motif; other site
979556008425	Walker B; other site
979556008426	D-loop; other site
979556008427	H-loop/switch region; other site
979556008428	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008429	dimer interface [polypeptide binding]; other site
979556008430	conserved gate region; other site
979556008431	putative PBP binding loops; other site
979556008432	ABC-ATPase subunit interface; other site
979556008433	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
979556008434	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
979556008435	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
979556008436	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
979556008437	Walker A/P-loop; other site
979556008438	ATP binding site [chemical binding]; other site
979556008439	Q-loop/lid; other site
979556008440	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556008441	ABC transporter signature motif; other site
979556008442	Walker B; other site
979556008443	D-loop; other site
979556008444	ABC transporter; Region: ABC_tran_2; pfam12848
979556008445	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556008446	MarR family; Region: MarR_2; cl17246
979556008447	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14352
979556008448	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
979556008449	Substrate binding site; other site
979556008450	Mg++ binding site; other site
979556008451	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
979556008452	active site
979556008453	substrate binding site [chemical binding]; other site
979556008454	CoA binding site [chemical binding]; other site
979556008455	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
979556008456	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK03092
979556008457	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556008458	active site
979556008459	ApbE family; Region: ApbE; pfam02424
979556008460	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
979556008461	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
979556008462	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cd00322
979556008463	FAD binding pocket [chemical binding]; other site
979556008464	conserved FAD binding motif [chemical binding]; other site
979556008465	phosphate binding motif [ion binding]; other site
979556008466	beta-alpha-beta structure motif; other site
979556008467	NAD binding pocket [chemical binding]; other site
979556008468	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
979556008469	putative active site [active]
979556008470	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556008471	dimer interface [polypeptide binding]; other site
979556008472	phosphorylation site [posttranslational modification]
979556008473	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
979556008474	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556008475	ATP binding site [chemical binding]; other site
979556008476	Mg2+ binding site [ion binding]; other site
979556008477	G-X-G motif; other site
979556008478	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556008479	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556008480	active site
979556008481	phosphorylation site [posttranslational modification]
979556008482	intermolecular recognition site; other site
979556008483	dimerization interface [polypeptide binding]; other site
979556008484	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556008485	DNA binding site [nucleotide binding]
979556008486	VanZ like family; Region: VanZ; pfam04892
979556008487	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
979556008488	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
979556008489	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
979556008490	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
979556008491	AAA domain; Region: AAA_33; pfam13671
979556008492	ATP-binding site [chemical binding]; other site
979556008493	Gluconate-6-phosphate binding site [chemical binding]; other site
979556008494	Transcriptional regulators [Transcription]; Region: FadR; COG2186
979556008495	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556008496	DNA-binding site [nucleotide binding]; DNA binding site
979556008497	FCD domain; Region: FCD; cl11656
979556008498	fructuronate transporter; Provisional; Region: PRK10034; cl15264
979556008499	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
979556008500	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
979556008501	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
979556008502	NADP binding site [chemical binding]; other site
979556008503	homodimer interface [polypeptide binding]; other site
979556008504	active site
979556008505	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
979556008506	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
979556008507	putative NAD(P) binding site [chemical binding]; other site
979556008508	catalytic Zn binding site [ion binding]; other site
979556008509	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
979556008510	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
979556008511	Putative D-isomer specific 2-hydroxyacid dehydrogenase; Region: 2-Hacid_dh_1; cd05300
979556008512	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
979556008513	NAD binding site [chemical binding]; other site
979556008514	ligand binding site [chemical binding]; other site
979556008515	catalytic site [active]
979556008516	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556008517	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008518	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556008519	putative substrate translocation pore; other site
979556008520	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556008521	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
979556008522	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
979556008523	5S rRNA interface [nucleotide binding]; other site
979556008524	CTC domain interface [polypeptide binding]; other site
979556008525	L16 interface [polypeptide binding]; other site
979556008526	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
979556008527	putative active site [active]
979556008528	catalytic residue [active]
979556008529	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
979556008530	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
979556008531	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556008532	ATP binding site [chemical binding]; other site
979556008533	putative Mg++ binding site [ion binding]; other site
979556008534	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556008535	nucleotide binding region [chemical binding]; other site
979556008536	ATP-binding site [chemical binding]; other site
979556008537	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
979556008538	SdpI/YhfL protein family; Region: SdpI; pfam13630
979556008539	UPF0126 domain; Region: UPF0126; pfam03458
979556008540	UPF0126 domain; Region: UPF0126; pfam03458
979556008541	Predicted membrane protein [Function unknown]; Region: COG2860
979556008542	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
979556008543	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
979556008544	putative trimer interface [polypeptide binding]; other site
979556008545	putative CoA binding site [chemical binding]; other site
979556008546	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
979556008547	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
979556008548	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: PRK12334
979556008549	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
979556008550	homodimer interface [polypeptide binding]; other site
979556008551	metal binding site [ion binding]; metal-binding site
979556008552	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
979556008553	histidyl-tRNA synthetase; Region: hisS; TIGR00442
979556008554	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
979556008555	dimer interface [polypeptide binding]; other site
979556008556	motif 1; other site
979556008557	active site
979556008558	motif 2; other site
979556008559	motif 3; other site
979556008560	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
979556008561	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
979556008562	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
979556008563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008564	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008565	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556008566	SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it...; Region: FeeA_FeeB_like; cd01836
979556008567	active site
979556008568	catalytic triad [active]
979556008569	oxyanion hole [active]
979556008570	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
979556008571	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
979556008572	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556008573	S-adenosylmethionine binding site [chemical binding]; other site
979556008574	enolase; Provisional; Region: eno; PRK00077
979556008575	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
979556008576	dimer interface [polypeptide binding]; other site
979556008577	metal binding site [ion binding]; metal-binding site
979556008578	substrate binding pocket [chemical binding]; other site
979556008579	Septum formation initiator; Region: DivIC; pfam04977
979556008580	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
979556008581	Protein of unknown function (DUF501); Region: DUF501; pfam04417
979556008582	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
979556008583	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
979556008584	active site
979556008585	catalytic residues [active]
979556008586	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
979556008587	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
979556008588	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556008589	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
979556008590	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
979556008591	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
979556008592	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
979556008593	Domain of unknown function DUF20; Region: UPF0118; pfam01594
979556008594	threonine dehydratase; Provisional; Region: PRK08198
979556008595	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
979556008596	tetramer interface [polypeptide binding]; other site
979556008597	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556008598	catalytic residue [active]
979556008599	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
979556008600	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
979556008601	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
979556008602	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
979556008603	Domain of unknown function (DUF4307); Region: DUF4307; pfam14155
979556008604	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
979556008605	Haemolysin-III related; Region: HlyIII; pfam03006
979556008606	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
979556008607	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
979556008608	catalytic residue [active]
979556008609	putative FPP diphosphate  binding site; other site
979556008610	putative FPP binding hydrophobic cleft; other site
979556008611	dimer interface [polypeptide binding]; other site
979556008612	putative IPP diphosphate binding site; other site
979556008613	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
979556008614	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
979556008615	putative active site [active]
979556008616	PhoH-like protein; Region: PhoH; pfam02562
979556008617	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556008618	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556008619	active site
979556008620	phosphorylation site [posttranslational modification]
979556008621	intermolecular recognition site; other site
979556008622	dimerization interface [polypeptide binding]; other site
979556008623	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556008624	DNA binding site [nucleotide binding]
979556008625	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
979556008626	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
979556008627	dimerization interface [polypeptide binding]; other site
979556008628	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556008629	dimer interface [polypeptide binding]; other site
979556008630	phosphorylation site [posttranslational modification]
979556008631	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556008632	ATP binding site [chemical binding]; other site
979556008633	Mg2+ binding site [ion binding]; other site
979556008634	G-X-G motif; other site
979556008635	fumarate hydratase; Reviewed; Region: fumC; PRK00485
979556008636	Class II fumarases; Region: Fumarase_classII; cd01362
979556008637	active site
979556008638	tetramer interface [polypeptide binding]; other site
979556008639	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
979556008640	active site clefts [active]
979556008641	zinc binding site [ion binding]; other site
979556008642	dimer interface [polypeptide binding]; other site
979556008643	Protein of unknown function (DUF4245); Region: DUF4245; pfam14030
979556008644	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
979556008645	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
979556008646	generic binding surface II; other site
979556008647	generic binding surface I; other site
979556008648	Exonuclease VII, large subunit; Region: Exonuc_VII_L; pfam02601
979556008649	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
979556008650	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
979556008651	RNA polymerase sigma factor SigL; Provisional; Region: PRK09645
979556008652	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556008653	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556008654	DNA binding residues [nucleotide binding]
979556008655	Putative zinc-finger; Region: zf-HC2; pfam13490
979556008656	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
979556008657	MOSC domain; Region: MOSC; pfam03473
979556008658	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
979556008659	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
979556008660	active site
979556008661	intersubunit interface [polypeptide binding]; other site
979556008662	zinc binding site [ion binding]; other site
979556008663	Na+ binding site [ion binding]; other site
979556008664	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
979556008665	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
979556008666	putative active site [active]
979556008667	RmuC family; Region: RmuC; pfam02646
979556008668	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
979556008669	active site
979556008670	substrate binding site [chemical binding]; other site
979556008671	catalytic site [active]
979556008672	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556008673	S-adenosylmethionine binding site [chemical binding]; other site
979556008674	GTP-binding protein YchF; Reviewed; Region: PRK09601
979556008675	YchF GTPase; Region: YchF; cd01900
979556008676	G1 box; other site
979556008677	GTP/Mg2+ binding site [chemical binding]; other site
979556008678	Switch I region; other site
979556008679	G2 box; other site
979556008680	Switch II region; other site
979556008681	G3 box; other site
979556008682	G4 box; other site
979556008683	G5 box; other site
979556008684	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
979556008685	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
979556008686	Int/Topo IB signature motif; other site
979556008687	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556008688	non-specific DNA binding site [nucleotide binding]; other site
979556008689	salt bridge; other site
979556008690	sequence-specific DNA binding site [nucleotide binding]; other site
979556008691	Restriction endonuclease; Region: Mrr_cat; pfam04471
979556008692	leucine-zipper of insertion element IS481; Region: LZ_Tnp_IS481; pfam13011
979556008693	Winged helix-turn helix; Region: HTH_29; pfam13551
979556008694	Integrase core domain; Region: rve; pfam00665
979556008695	Integrase core domain; Region: rve_3; pfam13683
979556008696	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
979556008697	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
979556008698	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
979556008699	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
979556008700	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
979556008701	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556008702	sequence-specific DNA binding site [nucleotide binding]; other site
979556008703	salt bridge; other site
979556008704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
979556008705	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
979556008706	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
979556008707	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
979556008708	CsbD-like; Region: CsbD; pfam05532
979556008709	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
979556008710	active site
979556008711	catalytic residues [active]
979556008712	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
979556008713	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
979556008714	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
979556008715	Uncharacterized bacterial subgroup of the N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei  (endonuclease VIII) base-excision repair DNA glycosylases; Region: BaFpgNei_N_1; cd08973
979556008716	putative DNA binding site [nucleotide binding]; other site
979556008717	catalytic residue [active]
979556008718	putative H2TH interface [polypeptide binding]; other site
979556008719	putative catalytic residues [active]
979556008720	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556008721	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
979556008722	intracellular protease, PfpI family; Region: PfpI; TIGR01382
979556008723	proposed catalytic triad [active]
979556008724	conserved cys residue [active]
979556008725	putative transporter; Provisional; Region: PRK10504
979556008726	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556008727	putative substrate translocation pore; other site
979556008728	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556008729	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556008730	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556008731	Walker A/P-loop; other site
979556008732	ATP binding site [chemical binding]; other site
979556008733	Q-loop/lid; other site
979556008734	ABC transporter signature motif; other site
979556008735	Walker B; other site
979556008736	D-loop; other site
979556008737	H-loop/switch region; other site
979556008738	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
979556008739	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
979556008740	active site
979556008741	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
979556008742	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
979556008743	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556008744	catalytic residue [active]
979556008745	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06543
979556008746	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
979556008747	dimerization interface [polypeptide binding]; other site
979556008748	active site
979556008749	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
979556008750	L-aspartate oxidase; Provisional; Region: PRK06175
979556008751	quinolinate synthetase; Provisional; Region: PRK09375
979556008752	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
979556008753	nudix motif; other site
979556008754	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
979556008755	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
979556008756	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
979556008757	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
979556008758	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
979556008759	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
979556008760	lipoyl attachment site [posttranslational modification]; other site
979556008761	glycine dehydrogenase; Provisional; Region: PRK05367
979556008762	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556008763	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556008764	catalytic residue [active]
979556008765	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
979556008766	tetramer interface [polypeptide binding]; other site
979556008767	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556008768	catalytic residue [active]
979556008769	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556008770	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
979556008771	CAAX protease self-immunity; Region: Abi; pfam02517
979556008772	The substrate-binding domain of mycobacterial lipoprotein Lpqw contains type 2 periplasmic binding fold; Region: PBP2_Lpqw; cd08501
979556008773	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
979556008774	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556008775	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556008776	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008777	dimer interface [polypeptide binding]; other site
979556008778	ABC-ATPase subunit interface; other site
979556008779	putative PBP binding loops; other site
979556008780	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
979556008781	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556008782	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
979556008783	dimer interface [polypeptide binding]; other site
979556008784	conserved gate region; other site
979556008785	ABC-ATPase subunit interface; other site
979556008786	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556008787	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556008788	Walker A/P-loop; other site
979556008789	ATP binding site [chemical binding]; other site
979556008790	Q-loop/lid; other site
979556008791	ABC transporter signature motif; other site
979556008792	Walker B; other site
979556008793	D-loop; other site
979556008794	H-loop/switch region; other site
979556008795	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556008796	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556008797	Walker A/P-loop; other site
979556008798	ATP binding site [chemical binding]; other site
979556008799	Q-loop/lid; other site
979556008800	ABC transporter signature motif; other site
979556008801	Walker B; other site
979556008802	D-loop; other site
979556008803	H-loop/switch region; other site
979556008804	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556008805	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
979556008806	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
979556008807	G1 box; other site
979556008808	putative GEF interaction site [polypeptide binding]; other site
979556008809	GTP/Mg2+ binding site [chemical binding]; other site
979556008810	Switch I region; other site
979556008811	G2 box; other site
979556008812	G3 box; other site
979556008813	Switch II region; other site
979556008814	G4 box; other site
979556008815	G5 box; other site
979556008816	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
979556008817	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
979556008818	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
979556008819	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556008820	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556008821	non-specific DNA binding site [nucleotide binding]; other site
979556008822	salt bridge; other site
979556008823	sequence-specific DNA binding site [nucleotide binding]; other site
979556008824	Cupin domain; Region: Cupin_2; cl17218
979556008825	AzlC protein; Region: AzlC; pfam03591
979556008826	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
979556008827	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556008828	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008829	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556008830	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008831	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556008832	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008833	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008834	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008835	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556008836	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556008837	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008838	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556008839	Ferredoxin [Energy production and conversion]; Region: COG1146
979556008840	4Fe-4S binding domain; Region: Fer4; pfam00037
979556008841	N-succinyldiaminopimelate aminotransferase; Reviewed; Region: PRK07865
979556008842	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556008843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556008844	homodimer interface [polypeptide binding]; other site
979556008845	catalytic residue [active]
979556008846	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
979556008847	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556008848	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
979556008849	Walker A/P-loop; other site
979556008850	ATP binding site [chemical binding]; other site
979556008851	Q-loop/lid; other site
979556008852	ABC transporter signature motif; other site
979556008853	Walker B; other site
979556008854	D-loop; other site
979556008855	H-loop/switch region; other site
979556008856	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
979556008857	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556008858	ABC transporter signature motif; other site
979556008859	Walker B; other site
979556008860	D-loop; other site
979556008861	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
979556008862	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
979556008863	Walker A/P-loop; other site
979556008864	ATP binding site [chemical binding]; other site
979556008865	Q-loop/lid; other site
979556008866	ABC transporter signature motif; other site
979556008867	Walker B; other site
979556008868	D-loop; other site
979556008869	H-loop/switch region; other site
979556008870	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
979556008871	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556008872	ABC-ATPase subunit  interface; other site
979556008873	dimer interface [polypeptide binding]; other site
979556008874	putative PBP binding regions; other site
979556008875	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
979556008876	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556008877	ABC-ATPase subunit  interface; other site
979556008878	dimer interface [polypeptide binding]; other site
979556008879	putative PBP binding regions; other site
979556008880	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
979556008881	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
979556008882	intersubunit interface [polypeptide binding]; other site
979556008883	Cupin domain; Region: Cupin_2; cl17218
979556008884	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
979556008885	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
979556008886	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
979556008887	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
979556008888	dimer interface [polypeptide binding]; other site
979556008889	active site
979556008890	citrylCoA binding site [chemical binding]; other site
979556008891	NADH binding [chemical binding]; other site
979556008892	cationic pore residues; other site
979556008893	oxalacetate/citrate binding site [chemical binding]; other site
979556008894	coenzyme A binding site [chemical binding]; other site
979556008895	catalytic triad [active]
979556008896	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
979556008897	Amidinotransferase; Region: Amidinotransf; cl12043
979556008898	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Region: DapD_actino; TIGR03535
979556008899	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
979556008900	putative trimer interface [polypeptide binding]; other site
979556008901	putative CoA binding site [chemical binding]; other site
979556008902	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13007
979556008903	M20 Peptidase actinobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_actinobac; cd05647
979556008904	metal binding site [ion binding]; metal-binding site
979556008905	putative dimer interface [polypeptide binding]; other site
979556008906	Protein of unknown function (DUF3117); Region: DUF3117; pfam11314
979556008907	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
979556008908	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
979556008909	Domain of unknown function DUF59; Region: DUF59; pfam01883
979556008910	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
979556008911	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556008912	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
979556008913	PRC-barrel domain; Region: PRC; pfam05239
979556008914	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
979556008915	MgtE intracellular N domain; Region: MgtE_N; smart00924
979556008916	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
979556008917	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG3571
979556008918	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
979556008919	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
979556008920	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
979556008921	proline aminopeptidase P II; Provisional; Region: PRK10879
979556008922	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
979556008923	active site
979556008924	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
979556008925	putative catalytic site [active]
979556008926	putative metal binding site [ion binding]; other site
979556008927	putative phosphate binding site [ion binding]; other site
979556008928	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
979556008929	putative catalytic site [active]
979556008930	putative phosphate binding site [ion binding]; other site
979556008931	putative metal binding site [ion binding]; other site
979556008932	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
979556008933	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
979556008934	active site
979556008935	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
979556008936	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
979556008937	DEAD-like helicases superfamily; Region: DEXDc; smart00487
979556008938	ATP binding site [chemical binding]; other site
979556008939	Mg++ binding site [ion binding]; other site
979556008940	motif III; other site
979556008941	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556008942	nucleotide binding region [chemical binding]; other site
979556008943	ATP-binding site [chemical binding]; other site
979556008944	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like; Region: MiaE_2; pfam13794
979556008945	Protein of unknown function (DUF3107); Region: DUF3107; pfam11305
979556008946	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
979556008947	Part of AAA domain; Region: AAA_19; pfam13245
979556008948	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
979556008949	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
979556008950	Part of AAA domain; Region: AAA_19; pfam13245
979556008951	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
979556008952	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
979556008953	active site
979556008954	ATP binding site [chemical binding]; other site
979556008955	substrate binding site [chemical binding]; other site
979556008956	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
979556008957	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
979556008958	putative NADH binding site [chemical binding]; other site
979556008959	putative active site [active]
979556008960	nudix motif; other site
979556008961	putative metal binding site [ion binding]; other site
979556008962	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
979556008963	Part of AAA domain; Region: AAA_19; pfam13245
979556008964	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
979556008965	Family description; Region: UvrD_C_2; pfam13538
979556008966	uncharacterized protein, coenzyme F420 biosynthesis associated; Region: DUF2342_F420; TIGR03883
979556008967	Uncharacterized conserved protein (DUF2342); Region: DUF2342; pfam10103
979556008968	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
979556008969	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
979556008970	protein binding site [polypeptide binding]; other site
979556008971	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
979556008972	Uncharacterized conserved protein [Function unknown]; Region: COG1615
979556008973	Uncharacterized protein family (UPF0182); Region: UPF0182; pfam03699
979556008974	prenyltransferase; Reviewed; Region: ubiA; PRK13105
979556008975	UbiA prenyltransferase family; Region: UbiA; pfam01040
979556008976	lycopene cyclase domain; Region: CarR_dom_SF; TIGR03462
979556008977	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
979556008978	phytoene desaturase; Region: crtI_fam; TIGR02734
979556008979	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
979556008980	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
979556008981	substrate binding pocket [chemical binding]; other site
979556008982	substrate-Mg2+ binding site; other site
979556008983	aspartate-rich region 1; other site
979556008984	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
979556008985	substrate binding pocket [chemical binding]; other site
979556008986	substrate-Mg2+ binding site; other site
979556008987	aspartate-rich region 1; other site
979556008988	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
979556008989	aspartate-rich region 2; other site
979556008990	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
979556008991	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
979556008992	active site
979556008993	metal binding site [ion binding]; metal-binding site
979556008994	nudix motif; other site
979556008995	MarR family; Region: MarR_2; pfam12802
979556008996	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
979556008997	Uncharacterized conserved protein [Function unknown]; Region: COG1262
979556008998	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
979556008999	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
979556009000	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556009001	Predicted amidohydrolase [General function prediction only]; Region: COG0388
979556009002	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
979556009003	putative active site [active]
979556009004	catalytic triad [active]
979556009005	putative dimer interface [polypeptide binding]; other site
979556009006	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
979556009007	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
979556009008	non-specific DNA binding site [nucleotide binding]; other site
979556009009	salt bridge; other site
979556009010	sequence-specific DNA binding site [nucleotide binding]; other site
979556009011	aminotransferase; Validated; Region: PRK07777
979556009012	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556009013	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556009014	homodimer interface [polypeptide binding]; other site
979556009015	catalytic residue [active]
979556009016	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
979556009017	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
979556009018	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
979556009019	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
979556009020	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
979556009021	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
979556009022	ExoA is involved in the biosynthesis of succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525
979556009023	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
979556009024	Ligand binding site; other site
979556009025	trehalose synthase-fused probable maltokinase; Region: TreS_Cterm; TIGR02457
979556009026	Uncharacterized protein, probably involved in trehalose biosynthesis [Carbohydrate transport and metabolism]; Region: Ble; COG3281
979556009027	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
979556009028	active site
979556009029	metal-binding site
979556009030	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
979556009031	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556009032	Walker A/P-loop; other site
979556009033	ATP binding site [chemical binding]; other site
979556009034	Q-loop/lid; other site
979556009035	ABC transporter signature motif; other site
979556009036	Walker B; other site
979556009037	D-loop; other site
979556009038	H-loop/switch region; other site
979556009039	Protein of unknown function (DUF3039); Region: DUF3039; pfam11238
979556009040	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
979556009041	active site
979556009042	glutamate racemase; Provisional; Region: PRK00865
979556009043	ribonuclease PH; Reviewed; Region: rph; PRK00173
979556009044	Ribonuclease PH; Region: RNase_PH_bact; cd11362
979556009045	hexamer interface [polypeptide binding]; other site
979556009046	active site
979556009047	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
979556009048	active site
979556009049	dimerization interface [polypeptide binding]; other site
979556009050	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
979556009051	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
979556009052	active site
979556009053	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
979556009054	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
979556009055	ATP-dependent DNA ligase; Reviewed; Region: PRK09632
979556009056	MtLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Mycobacterium tuberculosis (Mt)LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for...; Region: MtLigD_Pol_like; cd04863
979556009057	nucleotide binding site [chemical binding]; other site
979556009058	DNA polymerase Ligase (LigD); Region: LigD_N; cl11819
979556009059	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
979556009060	active site
979556009061	DNA binding site [nucleotide binding]
979556009062	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
979556009063	DNA binding site [nucleotide binding]
979556009064	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
979556009065	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
979556009066	putative DNA binding site [nucleotide binding]; other site
979556009067	putative homodimer interface [polypeptide binding]; other site
979556009068	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
979556009069	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
979556009070	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
979556009071	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
979556009072	active site
979556009073	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556009074	Zeta-crystallin with NADP-dependent quinone reductase activity (QOR); Region: zeta_crystallin; cd08253
979556009075	NAD(P) binding site [chemical binding]; other site
979556009076	Protein of unknown function (DUF1275); Region: DUF1275; cl01453
979556009077	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
979556009078	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
979556009079	PA/protease or protease-like domain interface [polypeptide binding]; other site
979556009080	M28 Zn-peptidase Streptomyces griseus Aminopeptidase and similar proteins; Region: M28_SGAP_like; cd03876
979556009081	Peptidase family M28; Region: Peptidase_M28; pfam04389
979556009082	active site
979556009083	metal binding site [ion binding]; metal-binding site
979556009084	Major Facilitator Superfamily; Region: MFS_1; pfam07690
979556009085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556009086	peptide chain release factor 2; Validated; Region: prfB; PRK00578
979556009087	This domain is found in peptide chain release factors; Region: PCRF; smart00937
979556009088	RF-1 domain; Region: RF-1; pfam00472
979556009089	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
979556009090	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556009091	Walker A/P-loop; other site
979556009092	ATP binding site [chemical binding]; other site
979556009093	Q-loop/lid; other site
979556009094	ABC transporter signature motif; other site
979556009095	Walker B; other site
979556009096	D-loop; other site
979556009097	H-loop/switch region; other site
979556009098	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
979556009099	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
979556009100	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
979556009101	SmpB-tmRNA interface; other site
979556009102	Protein of unknown function (DUF541); Region: SIMPL; cl01077
979556009103	YaeQ protein; Region: YaeQ; cl01913
979556009104	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
979556009105	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
979556009106	active site
979556009107	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
979556009108	nudix motif; other site
979556009109	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
979556009110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556009111	MarR family; Region: MarR; pfam01047
979556009112	Transcriptional regulator [Transcription]; Region: IclR; COG1414
979556009113	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
979556009114	Bacterial transcriptional regulator; Region: IclR; pfam01614
979556009115	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
979556009116	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
979556009117	putative acyltransferase; Provisional; Region: PRK05790
979556009118	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556009119	dimer interface [polypeptide binding]; other site
979556009120	active site
979556009121	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
979556009122	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
979556009123	active site
979556009124	homotetramer interface [polypeptide binding]; other site
979556009125	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
979556009126	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
979556009127	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
979556009128	acetolactate synthase 1 catalytic subunit; Validated; Region: PRK07789
979556009129	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
979556009130	PYR/PP interface [polypeptide binding]; other site
979556009131	dimer interface [polypeptide binding]; other site
979556009132	TPP binding site [chemical binding]; other site
979556009133	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
979556009134	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
979556009135	TPP-binding site [chemical binding]; other site
979556009136	dimer interface [polypeptide binding]; other site
979556009137	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
979556009138	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
979556009139	putative valine binding site [chemical binding]; other site
979556009140	dimer interface [polypeptide binding]; other site
979556009141	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
979556009142	ketol-acid reductoisomerase; Provisional; Region: PRK05479
979556009143	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
979556009144	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
979556009145	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
979556009146	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
979556009147	ligand binding site [chemical binding]; other site
979556009148	NAD binding site [chemical binding]; other site
979556009149	dimerization interface [polypeptide binding]; other site
979556009150	catalytic site [active]
979556009151	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
979556009152	putative L-serine binding site [chemical binding]; other site
979556009153	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556009154	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556009155	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
979556009156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556009157	putative substrate translocation pore; other site
979556009158	3-isopropylmalate dehydrogenase; Provisional; Region: PRK03437
979556009159	tartrate dehydrogenase; Region: TTC; TIGR02089
979556009160	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
979556009161	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
979556009162	homodimer interface [polypeptide binding]; other site
979556009163	substrate-cofactor binding pocket; other site
979556009164	catalytic residue [active]
979556009165	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
979556009166	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
979556009167	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556009168	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556009169	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556009170	catalytic residue [active]
979556009171	Transcriptional regulator [Transcription]; Region: LysR; COG0583
979556009172	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556009173	dimerization interface [polypeptide binding]; other site
979556009174	putative Zn2+ binding site [ion binding]; other site
979556009175	putative DNA binding site [nucleotide binding]; other site
979556009176	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_6; cd08423
979556009177	putative dimerization interface [polypeptide binding]; other site
979556009178	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
979556009179	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
979556009180	active site
979556009181	HIGH motif; other site
979556009182	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
979556009183	active site
979556009184	KMSKS motif; other site
979556009185	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
979556009186	MG2 domain; Region: A2M_N; pfam01835
979556009187	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
979556009188	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
979556009189	putative active site [active]
979556009190	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
979556009191	PA/protease or protease-like domain interface [polypeptide binding]; other site
979556009192	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
979556009193	catalytic residues [active]
979556009194	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
979556009195	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556009196	putative DNA binding site [nucleotide binding]; other site
979556009197	dimerization interface [polypeptide binding]; other site
979556009198	putative Zn2+ binding site [ion binding]; other site
979556009199	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
979556009200	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
979556009201	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
979556009202	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
979556009203	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
979556009204	putative substrate binding site [chemical binding]; other site
979556009205	putative ATP binding site [chemical binding]; other site
979556009206	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
979556009207	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
979556009208	active site
979556009209	phosphorylation site [posttranslational modification]
979556009210	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
979556009211	active site
979556009212	P-loop; other site
979556009213	phosphorylation site [posttranslational modification]
979556009214	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
979556009215	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
979556009216	dimerization domain swap beta strand [polypeptide binding]; other site
979556009217	regulatory protein interface [polypeptide binding]; other site
979556009218	active site
979556009219	regulatory phosphorylation site [posttranslational modification]; other site
979556009220	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
979556009221	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
979556009222	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
979556009223	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
979556009224	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556009225	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
979556009226	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
979556009227	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
979556009228	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
979556009229	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
979556009230	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
979556009231	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556009232	catalytic residue [active]
979556009233	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
979556009234	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
979556009235	substrate binding site [chemical binding]; other site
979556009236	ligand binding site [chemical binding]; other site
979556009237	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
979556009238	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
979556009239	substrate binding site [chemical binding]; other site
979556009240	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
979556009241	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
979556009242	hinge; other site
979556009243	active site
979556009244	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
979556009245	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
979556009246	putative acyl-acceptor binding pocket; other site
979556009247	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
979556009248	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
979556009249	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
979556009250	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
979556009251	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
979556009252	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556009253	Protein of unknown function (DUF3515); Region: DUF3515; pfam12028
979556009254	thiamine monophosphate kinase; Provisional; Region: PRK05731
979556009255	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
979556009256	ATP binding site [chemical binding]; other site
979556009257	dimerization interface [polypeptide binding]; other site
979556009258	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
979556009259	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556009260	S-adenosylmethionine binding site [chemical binding]; other site
979556009261	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
979556009262	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
979556009263	generic binding surface II; other site
979556009264	ssDNA binding site; other site
979556009265	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556009266	ATP binding site [chemical binding]; other site
979556009267	putative Mg++ binding site [ion binding]; other site
979556009268	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556009269	nucleotide binding region [chemical binding]; other site
979556009270	ATP-binding site [chemical binding]; other site
979556009271	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
979556009272	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
979556009273	active site
979556009274	(T/H)XGH motif; other site
979556009275	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
979556009276	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
979556009277	ribonuclease III; Reviewed; Region: rnc; PRK00102
979556009278	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
979556009279	dimerization interface [polypeptide binding]; other site
979556009280	active site
979556009281	metal binding site [ion binding]; metal-binding site
979556009282	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
979556009283	dsRNA binding site [nucleotide binding]; other site
979556009284	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
979556009285	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
979556009286	DNA binding site [nucleotide binding]
979556009287	catalytic residue [active]
979556009288	H2TH interface [polypeptide binding]; other site
979556009289	putative catalytic residues [active]
979556009290	turnover-facilitating residue; other site
979556009291	intercalation triad [nucleotide binding]; other site
979556009292	8OG recognition residue [nucleotide binding]; other site
979556009293	putative reading head residues; other site
979556009294	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556009295	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
979556009296	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
979556009297	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
979556009298	Coenzyme A binding pocket [chemical binding]; other site
979556009299	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
979556009300	AAA domain; Region: AAA_23; pfam13476
979556009301	Walker A/P-loop; other site
979556009302	ATP binding site [chemical binding]; other site
979556009303	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
979556009304	ABC transporter signature motif; other site
979556009305	Walker B; other site
979556009306	D-loop; other site
979556009307	H-loop/switch region; other site
979556009308	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
979556009309	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
979556009310	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
979556009311	Protein of unknown function (DUF2004); Region: DUF2004; pfam09406
979556009312	lipoyl synthase; Provisional; Region: PRK05481
979556009313	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
979556009314	FeS/SAM binding site; other site
979556009315	lipoate-protein ligase B; Provisional; Region: PRK14345
979556009316	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556009317	signal recognition particle protein; Provisional; Region: PRK10867
979556009318	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
979556009319	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
979556009320	P loop; other site
979556009321	GTP binding site [chemical binding]; other site
979556009322	Signal peptide binding domain; Region: SRP_SPB; pfam02978
979556009323	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
979556009324	active site
979556009325	catalytic triad [active]
979556009326	oxyanion hole [active]
979556009327	carboxylate-amine ligase; Provisional; Region: PRK13517
979556009328	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
979556009329	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14520
979556009330	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
979556009331	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
979556009332	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
979556009333	RimM N-terminal domain; Region: RimM; pfam01782
979556009334	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
979556009335	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
979556009336	active site
979556009337	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
979556009338	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
979556009339	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
979556009340	Catalytic site [active]
979556009341	ribonuclease HII; Validated; Region: rnhB; PRK00015
979556009342	RNA/DNA hybrid binding site [nucleotide binding]; other site
979556009343	active site
979556009344	Protein of unknown function (DUF2469); Region: DUF2469; pfam10611
979556009345	hypothetical protein; Reviewed; Region: PRK12497
979556009346	Mg chelatase-related protein; Region: TIGR00368
979556009347	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
979556009348	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
979556009349	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
979556009350	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
979556009351	DNA protecting protein DprA; Region: dprA; TIGR00732
979556009352	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
979556009353	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
979556009354	active site
979556009355	DNA binding site [nucleotide binding]
979556009356	Int/Topo IB signature motif; other site
979556009357	hypothetical protein; Provisional; Region: PRK09946
979556009358	Peptidase family M23; Region: Peptidase_M23; pfam01551
979556009359	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
979556009360	rRNA interaction site [nucleotide binding]; other site
979556009361	S8 interaction site; other site
979556009362	putative laminin-1 binding site; other site
979556009363	elongation factor Ts; Provisional; Region: tsf; PRK09377
979556009364	UBA/TS-N domain; Region: UBA; pfam00627
979556009365	Elongation factor TS; Region: EF_TS; pfam00889
979556009366	Elongation factor TS; Region: EF_TS; pfam00889
979556009367	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
979556009368	putative nucleotide binding site [chemical binding]; other site
979556009369	uridine monophosphate binding site [chemical binding]; other site
979556009370	homohexameric interface [polypeptide binding]; other site
979556009371	ribosome recycling factor; Reviewed; Region: frr; PRK00083
979556009372	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
979556009373	hinge region; other site
979556009374	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
979556009375	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
979556009376	DivIVA domain repeat protein; Region: divI1A_rptt_fam; TIGR03543
979556009377	DivIVA domain; Region: DivI1A_domain; TIGR03544
979556009378	DivIVA domain; Region: DivI1A_domain; TIGR03544
979556009379	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
979556009380	N-acetyl-D-glucosamine binding site [chemical binding]; other site
979556009381	catalytic residue [active]
979556009382	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556009383	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
979556009384	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
979556009385	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
979556009386	glycogen branching enzyme; Provisional; Region: PRK05402
979556009387	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
979556009388	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
979556009389	active site
979556009390	catalytic site [active]
979556009391	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
979556009392	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
979556009393	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
979556009394	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
979556009395	active site
979556009396	homodimer interface [polypeptide binding]; other site
979556009397	catalytic site [active]
979556009398	acceptor binding site [chemical binding]; other site
979556009399	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
979556009400	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
979556009401	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
979556009402	active site
979556009403	catalytic site [active]
979556009404	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
979556009405	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
979556009406	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
979556009407	catalytic residue [active]
979556009408	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
979556009409	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
979556009410	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
979556009411	nucleotide binding pocket [chemical binding]; other site
979556009412	K-X-D-G motif; other site
979556009413	catalytic site [active]
979556009414	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
979556009415	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
979556009416	Helix-hairpin-helix motif; Region: HHH; pfam00633
979556009417	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK05605
979556009418	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
979556009419	acyl-activating enzyme (AAE) consensus motif; other site
979556009420	putative AMP binding site [chemical binding]; other site
979556009421	putative active site [active]
979556009422	putative CoA binding site [chemical binding]; other site
979556009423	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
979556009424	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
979556009425	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
979556009426	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
979556009427	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
979556009428	GatB domain; Region: GatB_Yqey; smart00845
979556009429	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
979556009430	active site
979556009431	DNA polymerase IV; Validated; Region: PRK02406
979556009432	DNA binding site [nucleotide binding]
979556009433	hypothetical protein; Provisional; Region: PRK06547
979556009434	Domain of unknown function (DUF2017); Region: DUF2017; pfam09438
979556009435	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; cl00933
979556009436	Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein; Region: MMP_ACEL2062; cd12952
979556009437	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
979556009438	putative active site [active]
979556009439	putative substrate binding site [chemical binding]; other site
979556009440	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
979556009441	dimer interface [polypeptide binding]; other site
979556009442	catalytic site [active]
979556009443	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
979556009444	Predicted membrane protein [Function unknown]; Region: COG2364
979556009445	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
979556009446	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556009447	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556009448	homodimer interface [polypeptide binding]; other site
979556009449	catalytic residue [active]
979556009450	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
979556009451	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
979556009452	dimer interface [polypeptide binding]; other site
979556009453	ssDNA binding site [nucleotide binding]; other site
979556009454	tetramer (dimer of dimers) interface [polypeptide binding]; other site
979556009455	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
979556009456	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556009457	Walker A/P-loop; other site
979556009458	ATP binding site [chemical binding]; other site
979556009459	Q-loop/lid; other site
979556009460	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556009461	ABC transporter; Region: ABC_tran_2; pfam12848
979556009462	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556009463	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
979556009464	active site
979556009465	Acyl-CoA thioesterase [Lipid metabolism]; Region: TesB; COG1946
979556009466	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
979556009467	active site
979556009468	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
979556009469	catalytic triad [active]
979556009470	dimer interface [polypeptide binding]; other site
979556009471	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
979556009472	apolar tunnel; other site
979556009473	heme binding site [chemical binding]; other site
979556009474	dimerization interface [polypeptide binding]; other site
979556009475	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
979556009476	Mechanosensitive ion channel; Region: MS_channel; pfam00924
979556009477	aminopeptidase N, Streptomyces lividans type; Region: pepN_strep_liv; TIGR02412
979556009478	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
979556009479	Zn binding site [ion binding]; other site
979556009480	ferrochelatase; Reviewed; Region: hemH; PRK00035
979556009481	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
979556009482	C-terminal domain interface [polypeptide binding]; other site
979556009483	active site
979556009484	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
979556009485	active site
979556009486	N-terminal domain interface [polypeptide binding]; other site
979556009487	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
979556009488	Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266
979556009489	N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases; Region: AcNei1_N; cd08970
979556009490	putative DNA binding site [nucleotide binding]; other site
979556009491	catalytic residue [active]
979556009492	putative H2TH interface [polypeptide binding]; other site
979556009493	putative catalytic residues [active]
979556009494	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
979556009495	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
979556009496	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
979556009497	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556009498	Amidohydrolase family; Region: Amidohydro_3; pfam07969
979556009499	active site
979556009500	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556009501	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009502	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009503	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556009504	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009505	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556009506	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556009507	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009508	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556009509	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556009510	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
979556009511	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009512	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009513	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
979556009514	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
979556009515	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
979556009516	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
979556009517	dimerization interface [polypeptide binding]; other site
979556009518	DPS ferroxidase diiron center [ion binding]; other site
979556009519	ion pore; other site
979556009520	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556009521	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
979556009522	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
979556009523	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
979556009524	trimer interface [polypeptide binding]; other site
979556009525	putative metal binding site [ion binding]; other site
979556009526	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
979556009527	SdpI/YhfL protein family; Region: SdpI; pfam13630
979556009528	trigger factor; Provisional; Region: tig; PRK01490
979556009529	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
979556009530	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
979556009531	Tetratrico peptide repeat; Region: TPR_5; pfam12688
979556009532	Clp protease; Region: CLP_protease; pfam00574
979556009533	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
979556009534	oligomer interface [polypeptide binding]; other site
979556009535	active site residues [active]
979556009536	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
979556009537	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
979556009538	oligomer interface [polypeptide binding]; other site
979556009539	active site residues [active]
979556009540	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
979556009541	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
979556009542	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556009543	Walker A motif; other site
979556009544	ATP binding site [chemical binding]; other site
979556009545	Walker B motif; other site
979556009546	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
979556009547	Domain of unknown function (DUF222); Region: DUF222; pfam02720
979556009548	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556009549	active site
979556009550	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
979556009551	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
979556009552	active site
979556009553	Zn binding site [ion binding]; other site
979556009554	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556009555	dimerization interface [polypeptide binding]; other site
979556009556	putative DNA binding site [nucleotide binding]; other site
979556009557	putative Zn2+ binding site [ion binding]; other site
979556009558	valyl-tRNA synthetase; Reviewed; Region: valS; PRK13208
979556009559	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556009560	active site
979556009561	HIGH motif; other site
979556009562	nucleotide binding site [chemical binding]; other site
979556009563	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556009564	active site
979556009565	KMSKS motif; other site
979556009566	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
979556009567	tRNA binding surface [nucleotide binding]; other site
979556009568	anticodon binding site; other site
979556009569	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
979556009570	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
979556009571	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
979556009572	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556009573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
979556009574	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
979556009575	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
979556009576	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556009577	Walker A/P-loop; other site
979556009578	ATP binding site [chemical binding]; other site
979556009579	Q-loop/lid; other site
979556009580	ABC transporter signature motif; other site
979556009581	Walker B; other site
979556009582	D-loop; other site
979556009583	H-loop/switch region; other site
979556009584	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
979556009585	Walker A/P-loop; other site
979556009586	ATP binding site [chemical binding]; other site
979556009587	Q-loop/lid; other site
979556009588	ABC transporter signature motif; other site
979556009589	Walker B; other site
979556009590	D-loop; other site
979556009591	H-loop/switch region; other site
979556009592	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
979556009593	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
979556009594	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
979556009595	HIGH motif; other site
979556009596	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556009597	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
979556009598	active site
979556009599	KMSKS motif; other site
979556009600	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
979556009601	tRNA binding surface [nucleotide binding]; other site
979556009602	anticodon binding site; other site
979556009603	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
979556009604	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
979556009605	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
979556009606	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
979556009607	active site
979556009608	multimer interface [polypeptide binding]; other site
979556009609	Vitamin K epoxide reductase family in bacteria; Region: VKOR_5; cd12922
979556009610	putative active site [active]
979556009611	redox center [active]
979556009612	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
979556009613	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
979556009614	homodimer interface [polypeptide binding]; other site
979556009615	oligonucleotide binding site [chemical binding]; other site
979556009616	Protein of unknown function (DUF4031); Region: DUF4031; pfam13223
979556009617	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
979556009618	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
979556009619	GTPase CgtA; Reviewed; Region: obgE; PRK12296
979556009620	GTP1/OBG; Region: GTP1_OBG; pfam01018
979556009621	Obg GTPase; Region: Obg; cd01898
979556009622	G1 box; other site
979556009623	GTP/Mg2+ binding site [chemical binding]; other site
979556009624	Switch I region; other site
979556009625	G2 box; other site
979556009626	G3 box; other site
979556009627	Switch II region; other site
979556009628	G4 box; other site
979556009629	G5 box; other site
979556009630	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
979556009631	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
979556009632	homotetrameric interface [polypeptide binding]; other site
979556009633	putative phosphate binding site [ion binding]; other site
979556009634	putative allosteric binding site; other site
979556009635	nucleotide binding site [chemical binding]; other site
979556009636	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
979556009637	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
979556009638	putative catalytic cysteine [active]
979556009639	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
979556009640	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
979556009641	active site
979556009642	(T/H)XGH motif; other site
979556009643	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
979556009644	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
979556009645	Uncharacterized conserved protein [Function unknown]; Region: COG4850
979556009646	Uncharacterized conserved protein (DUF2183); Region: DUF2183; pfam09949
979556009647	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
979556009648	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
979556009649	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
979556009650	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
979556009651	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
979556009652	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
979556009653	HIGH motif; other site
979556009654	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
979556009655	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556009656	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
979556009657	active site
979556009658	KMSKS motif; other site
979556009659	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
979556009660	tRNA binding surface [nucleotide binding]; other site
979556009661	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
979556009662	SLBB domain; Region: SLBB; pfam10531
979556009663	comEA protein; Region: comE; TIGR01259
979556009664	Competence protein; Region: Competence; cl00471
979556009665	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
979556009666	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
979556009667	hypothetical protein; Reviewed; Region: PRK07914
979556009668	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
979556009669	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556009670	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
979556009671	Serine hydrolase; Region: Ser_hydrolase; cl17834
979556009672	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
979556009673	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556009674	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556009675	homodimer interface [polypeptide binding]; other site
979556009676	catalytic residue [active]
979556009677	GTP-binding protein LepA; Provisional; Region: PRK05433
979556009678	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
979556009679	G1 box; other site
979556009680	putative GEF interaction site [polypeptide binding]; other site
979556009681	GTP/Mg2+ binding site [chemical binding]; other site
979556009682	Switch I region; other site
979556009683	G2 box; other site
979556009684	G3 box; other site
979556009685	Switch II region; other site
979556009686	G4 box; other site
979556009687	G5 box; other site
979556009688	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
979556009689	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
979556009690	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
979556009691	Domain of unknown function (DUF1990); Region: DUF1990; cl01969
979556009692	coproporphyrinogen III oxidase; Validated; Region: PRK05628
979556009693	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
979556009694	chaperone protein DnaJ; Provisional; Region: PRK14278
979556009695	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
979556009696	HSP70 interaction site [polypeptide binding]; other site
979556009697	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
979556009698	Zn binding sites [ion binding]; other site
979556009699	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
979556009700	dimer interface [polypeptide binding]; other site
979556009701	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
979556009702	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
979556009703	nucleotide binding site/active site [active]
979556009704	HIT family signature motif; other site
979556009705	catalytic residue [active]
979556009706	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
979556009707	PhoH-like protein; Region: PhoH; pfam02562
979556009708	metal-binding heat shock protein; Provisional; Region: PRK00016
979556009709	Domain of unknown function DUF21; Region: DUF21; pfam01595
979556009710	FOG: CBS domain [General function prediction only]; Region: COG0517
979556009711	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
979556009712	Transporter associated domain; Region: CorC_HlyC; smart01091
979556009713	GTPase Era; Reviewed; Region: era; PRK00089
979556009714	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
979556009715	G1 box; other site
979556009716	GTP/Mg2+ binding site [chemical binding]; other site
979556009717	Switch I region; other site
979556009718	G2 box; other site
979556009719	Switch II region; other site
979556009720	G3 box; other site
979556009721	G4 box; other site
979556009722	G5 box; other site
979556009723	KH domain; Region: KH_2; pfam07650
979556009724	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
979556009725	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
979556009726	putative NAD(P) binding site [chemical binding]; other site
979556009727	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
979556009728	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
979556009729	2-isopropylmalate synthase; Validated; Region: PRK03739
979556009730	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
979556009731	active site
979556009732	catalytic residues [active]
979556009733	metal binding site [ion binding]; metal-binding site
979556009734	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
979556009735	Methyltransferase domain; Region: Methyltransf_31; pfam13847
979556009736	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556009737	S-adenosylmethionine binding site [chemical binding]; other site
979556009738	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
979556009739	MOSC domain; Region: MOSC; pfam03473
979556009740	acyl-coenzyme A oxidase; Region: PLN02526
979556009741	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556009742	active site
979556009743	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
979556009744	CoA-transferase family III; Region: CoA_transf_3; pfam02515
979556009745	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
979556009746	RHS Repeat; Region: RHS_repeat; cl11982
979556009747	RHS Repeat; Region: RHS_repeat; pfam05593
979556009748	RHS Repeat; Region: RHS_repeat; pfam05593
979556009749	RHS Repeat; Region: RHS_repeat; cl11982
979556009750	RHS Repeat; Region: RHS_repeat; pfam05593
979556009751	RHS Repeat; Region: RHS_repeat; pfam05593
979556009752	RHS Repeat; Region: RHS_repeat; cl11982
979556009753	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
979556009754	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
979556009755	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
979556009756	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
979556009757	Recombination protein O N terminal; Region: RecO_N; pfam11967
979556009758	Recombination protein O C terminal; Region: RecO_C; pfam02565
979556009759	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
979556009760	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
979556009761	catalytic residue [active]
979556009762	putative FPP diphosphate  binding site; other site
979556009763	putative FPP binding hydrophobic cleft; other site
979556009764	dimer interface [polypeptide binding]; other site
979556009765	putative IPP diphosphate binding site; other site
979556009766	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
979556009767	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
979556009768	catalytic residues [active]
979556009769	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
979556009770	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
979556009771	FMN binding site [chemical binding]; other site
979556009772	active site
979556009773	catalytic residues [active]
979556009774	substrate binding site [chemical binding]; other site
979556009775	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK03007
979556009776	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
979556009777	Zn2+ binding site [ion binding]; other site
979556009778	Mg2+ binding site [ion binding]; other site
979556009779	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
979556009780	DNA primase; Validated; Region: dnaG; PRK05667
979556009781	CHC2 zinc finger; Region: zf-CHC2; pfam01807
979556009782	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
979556009783	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
979556009784	active site
979556009785	metal binding site [ion binding]; metal-binding site
979556009786	interdomain interaction site; other site
979556009787	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
979556009788	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
979556009789	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556009790	Walker A/P-loop; other site
979556009791	ATP binding site [chemical binding]; other site
979556009792	Q-loop/lid; other site
979556009793	ABC transporter signature motif; other site
979556009794	Walker B; other site
979556009795	D-loop; other site
979556009796	H-loop/switch region; other site
979556009797	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
979556009798	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
979556009799	Glutaminase; Region: Glutaminase; cl00907
979556009800	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
979556009801	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
979556009802	active site
979556009803	catalytic residues [active]
979556009804	metal binding site [ion binding]; metal-binding site
979556009805	Magnesium transporter NIPA; Region: Mg_trans_NIPA; pfam05653
979556009806	methionine synthase; Provisional; Region: PRK01207
979556009807	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
979556009808	substrate binding site [chemical binding]; other site
979556009809	THF binding site; other site
979556009810	zinc-binding site [ion binding]; other site
979556009811	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
979556009812	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
979556009813	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
979556009814	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
979556009815	dimerization interface [polypeptide binding]; other site
979556009816	Phospholipid methyltransferase; Region: PEMT; cl17370
979556009817	Domain of unknown function DUF21; Region: DUF21; pfam01595
979556009818	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
979556009819	Domain of unknown function DUF21; Region: DUF21; pfam01595
979556009820	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
979556009821	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
979556009822	Transporter associated domain; Region: CorC_HlyC; pfam03471
979556009823	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
979556009824	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
979556009825	Walker A/P-loop; other site
979556009826	ATP binding site [chemical binding]; other site
979556009827	Q-loop/lid; other site
979556009828	ABC transporter signature motif; other site
979556009829	Walker B; other site
979556009830	D-loop; other site
979556009831	H-loop/switch region; other site
979556009832	Predicted transcriptional regulators [Transcription]; Region: COG1725
979556009833	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556009834	DNA-binding site [nucleotide binding]; DNA binding site
979556009835	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
979556009836	dimerization interface [polypeptide binding]; other site
979556009837	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556009838	dimer interface [polypeptide binding]; other site
979556009839	phosphorylation site [posttranslational modification]
979556009840	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556009841	ATP binding site [chemical binding]; other site
979556009842	Mg2+ binding site [ion binding]; other site
979556009843	G-X-G motif; other site
979556009844	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
979556009845	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556009846	active site
979556009847	phosphorylation site [posttranslational modification]
979556009848	intermolecular recognition site; other site
979556009849	dimerization interface [polypeptide binding]; other site
979556009850	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
979556009851	DNA binding site [nucleotide binding]
979556009852	Protein of unknown function (DUF3145); Region: DUF3145; pfam11343
979556009853	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
979556009854	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
979556009855	dimer interface [polypeptide binding]; other site
979556009856	active site
979556009857	acyl carrier protein; Provisional; Region: acpP; PRK00982
979556009858	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
979556009859	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
979556009860	dimer interface [polypeptide binding]; other site
979556009861	active site
979556009862	CoA binding pocket [chemical binding]; other site
979556009863	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
979556009864	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
979556009865	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
979556009866	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
979556009867	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
979556009868	dimer interface [polypeptide binding]; other site
979556009869	TPP-binding site [chemical binding]; other site
979556009870	Protein of unknown function (DUF1345); Region: DUF1345; cl01753
979556009871	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
979556009872	Putative zinc ribbon domain; Region: DUF164; pfam02591
979556009873	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
979556009874	active site
979556009875	DNA binding site [nucleotide binding]
979556009876	catalytic site [active]
979556009877	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
979556009878	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
979556009879	nucleotide binding site [chemical binding]; other site
979556009880	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
979556009881	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
979556009882	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
979556009883	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Provisional; Region: PRK14109
979556009884	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
979556009885	metal binding triad; other site
979556009886	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
979556009887	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
979556009888	metal binding triad; other site
979556009889	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
979556009890	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK05605
979556009891	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
979556009892	putative AMP binding site [chemical binding]; other site
979556009893	putative active site [active]
979556009894	acyl-activating enzyme (AAE) consensus motif; other site
979556009895	putative CoA binding site [chemical binding]; other site
979556009896	Uncharacterized conserved protein (DUF2277); Region: DUF2277; pfam10041
979556009897	Alpha/beta hydrolase; Region: Abhydrolase_8; pfam06259
979556009898	glutamine synthetase, type I; Region: GlnA; TIGR00653
979556009899	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
979556009900	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
979556009901	RDD family; Region: RDD; pfam06271
979556009902	Domain of unknown function (DUF4191); Region: DUF4191; pfam13829
979556009903	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Region: SucB_Actino; TIGR02927
979556009904	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
979556009905	E3 interaction surface; other site
979556009906	lipoyl attachment site [posttranslational modification]; other site
979556009907	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
979556009908	E3 interaction surface; other site
979556009909	lipoyl attachment site [posttranslational modification]; other site
979556009910	e3 binding domain; Region: E3_binding; pfam02817
979556009911	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
979556009912	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
979556009913	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
979556009914	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
979556009915	multifunctional aminopeptidase A; Provisional; Region: PRK00913
979556009916	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
979556009917	interface (dimer of trimers) [polypeptide binding]; other site
979556009918	Substrate-binding/catalytic site; other site
979556009919	Zn-binding sites [ion binding]; other site
979556009920	PAC2 family; Region: PAC2; pfam09754
979556009921	RNA polymerase sigma factor SigB; Reviewed; Region: PRK07921
979556009922	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
979556009923	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
979556009924	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
979556009925	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
979556009926	DNA binding residues [nucleotide binding]
979556009927	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
979556009928	Sugar-transfer associated ATP-grasp; Region: ATPgrasp_ST; pfam14397
979556009929	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
979556009930	alanine racemase; Reviewed; Region: alr; PRK00053
979556009931	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
979556009932	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
979556009933	catalytic residue [active]
979556009934	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
979556009935	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556009936	ATP binding site [chemical binding]; other site
979556009937	Mg2+ binding site [ion binding]; other site
979556009938	G-X-G motif; other site
979556009939	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
979556009940	anchoring element; other site
979556009941	dimer interface [polypeptide binding]; other site
979556009942	ATP binding site [chemical binding]; other site
979556009943	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
979556009944	active site
979556009945	metal binding site [ion binding]; metal-binding site
979556009946	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
979556009947	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
979556009948	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
979556009949	CAP-like domain; other site
979556009950	active site
979556009951	primary dimer interface [polypeptide binding]; other site
979556009952	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
979556009953	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
979556009954	Protein of unknown function (DUF3071); Region: DUF3071; pfam11268
979556009955	Domain of unknown function (DUF4193); Region: DUF4193; pfam13834
979556009956	Protein of unknown function (DUF3093); Region: DUF3093; pfam11292
979556009957	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
979556009958	trimer interface [polypeptide binding]; other site
979556009959	active site
979556009960	Protein of unknown function (DUF3710); Region: DUF3710; pfam12502
979556009961	Protein of unknown function (DUF3159); Region: DUF3159; pfam11361
979556009962	aconitate hydratase; Validated; Region: PRK09277
979556009963	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
979556009964	substrate binding site [chemical binding]; other site
979556009965	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
979556009966	ligand binding site [chemical binding]; other site
979556009967	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
979556009968	substrate binding site [chemical binding]; other site
979556009969	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
979556009970	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
979556009971	TPP-binding site; other site
979556009972	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
979556009973	PYR/PP interface [polypeptide binding]; other site
979556009974	dimer interface [polypeptide binding]; other site
979556009975	TPP binding site [chemical binding]; other site
979556009976	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
979556009977	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
979556009978	substrate binding site [chemical binding]; other site
979556009979	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
979556009980	oxyanion hole (OAH) forming residues; other site
979556009981	trimer interface [polypeptide binding]; other site
979556009982	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
979556009983	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
979556009984	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
979556009985	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
979556009986	dimer interface [polypeptide binding]; other site
979556009987	active site
979556009988	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
979556009989	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
979556009990	catalytic site [active]
979556009991	putative active site [active]
979556009992	putative substrate binding site [chemical binding]; other site
979556009993	HRDC domain; Region: HRDC; pfam00570
979556009994	Protein of unknown function (DUF3000); Region: DUF3000; pfam11452
979556009995	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
979556009996	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556009997	Fe-S metabolism associated domain; Region: SufE; cl00951
979556009998	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
979556009999	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
979556010000	active site residue [active]
979556010001	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
979556010002	active site residue [active]
979556010003	AFG1-like ATPase; Region: AFG1_ATPase; pfam03969
979556010004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
979556010005	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
979556010006	PemK-like protein; Region: PemK; pfam02452
979556010007	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
979556010008	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
979556010009	Orbivirus outer capsid protein VP5; Region: Orbi_VP5; pfam00901
979556010010	PPOX class probable F420-dependent enzyme; Region: Rv1155_F420; TIGR03618
979556010011	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
979556010012	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
979556010013	transmembrane helices; other site
979556010014	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cl15768
979556010015	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
979556010016	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
979556010017	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
979556010018	active site
979556010019	dimer interface [polypeptide binding]; other site
979556010020	motif 1; other site
979556010021	motif 2; other site
979556010022	motif 3; other site
979556010023	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
979556010024	anticodon binding site; other site
979556010025	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
979556010026	nucleotide binding site/active site [active]
979556010027	HIT family signature motif; other site
979556010028	catalytic residue [active]
979556010029	pyridoxamine kinase; Validated; Region: PRK05756
979556010030	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
979556010031	dimer interface [polypeptide binding]; other site
979556010032	pyridoxal binding site [chemical binding]; other site
979556010033	ATP binding site [chemical binding]; other site
979556010034	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
979556010035	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
979556010036	DNA-binding site [nucleotide binding]; DNA binding site
979556010037	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556010038	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556010039	homodimer interface [polypeptide binding]; other site
979556010040	catalytic residue [active]
979556010041	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
979556010042	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
979556010043	active site
979556010044	multimer interface [polypeptide binding]; other site
979556010045	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
979556010046	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
979556010047	predicted active site [active]
979556010048	catalytic triad [active]
979556010049	hypothetical protein; Validated; Region: PRK00110
979556010050	Holliday junction resolvase; Reviewed; Region: ruvC; PRK00039
979556010051	active site
979556010052	putative DNA-binding cleft [nucleotide binding]; other site
979556010053	dimer interface [polypeptide binding]; other site
979556010054	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
979556010055	RuvA N terminal domain; Region: RuvA_N; pfam01330
979556010056	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
979556010057	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556010058	Walker A motif; other site
979556010059	ATP binding site [chemical binding]; other site
979556010060	Walker B motif; other site
979556010061	arginine finger; other site
979556010062	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
979556010063	Preprotein translocase subunit; Region: YajC; pfam02699
979556010064	protein-export membrane protein SecD; Region: secD; TIGR01129
979556010065	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
979556010066	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
979556010067	Protein export membrane protein; Region: SecD_SecF; cl14618
979556010068	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
979556010069	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
979556010070	Zn2+ binding site [ion binding]; other site
979556010071	Mg2+ binding site [ion binding]; other site
979556010072	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
979556010073	synthetase active site [active]
979556010074	NTP binding site [chemical binding]; other site
979556010075	metal binding site [ion binding]; metal-binding site
979556010076	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
979556010077	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
979556010078	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
979556010079	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
979556010080	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
979556010081	Walker A motif; other site
979556010082	ATP binding site [chemical binding]; other site
979556010083	Walker B motif; other site
979556010084	recombination factor protein RarA; Reviewed; Region: PRK13342
979556010085	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
979556010086	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
979556010087	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
979556010088	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
979556010089	RNA binding surface [nucleotide binding]; other site
979556010090	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
979556010091	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
979556010092	motif 1; other site
979556010093	active site
979556010094	motif 2; other site
979556010095	motif 3; other site
979556010096	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
979556010097	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
979556010098	YceG-like family; Region: YceG; pfam02618
979556010099	proteins similar to Escherichia coli yceG; Region: yceG_like; cl17666
979556010100	dimerization interface [polypeptide binding]; other site
979556010101	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
979556010102	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
979556010103	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
979556010104	shikimate binding site; other site
979556010105	NAD(P) binding site [chemical binding]; other site
979556010106	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
979556010107	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
979556010108	Tetramer interface [polypeptide binding]; other site
979556010109	active site
979556010110	FMN-binding site [chemical binding]; other site
979556010111	shikimate kinase; Reviewed; Region: aroK; PRK00131
979556010112	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
979556010113	ADP binding site [chemical binding]; other site
979556010114	magnesium binding site [ion binding]; other site
979556010115	putative shikimate binding site; other site
979556010116	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
979556010117	active site
979556010118	dimer interface [polypeptide binding]; other site
979556010119	metal binding site [ion binding]; metal-binding site
979556010120	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556010121	metabolite-proton symporter; Region: 2A0106; TIGR00883
979556010122	putative substrate translocation pore; other site
979556010123	shikimate 5-dehydrogenase; Reviewed; Region: PRK12549
979556010124	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
979556010125	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
979556010126	NAD(P) binding site [chemical binding]; other site
979556010127	shikimate binding site; other site
979556010128	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
979556010129	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
979556010130	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
979556010131	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
979556010132	Metal-binding active site; metal-binding site
979556010133	4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185
979556010134	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
979556010135	active site
979556010136	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
979556010137	active site
979556010138	metal binding site [ion binding]; metal-binding site
979556010139	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
979556010140	Dehydroquinase class II; Region: DHquinase_II; pfam01220
979556010141	active site
979556010142	trimer interface [polypeptide binding]; other site
979556010143	dimer interface [polypeptide binding]; other site
979556010144	elongation factor P; Validated; Region: PRK00529
979556010145	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
979556010146	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
979556010147	RNA binding site [nucleotide binding]; other site
979556010148	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
979556010149	RNA binding site [nucleotide binding]; other site
979556010150	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
979556010151	putative RNA binding site [nucleotide binding]; other site
979556010152	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
979556010153	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556010154	ATP binding site [chemical binding]; other site
979556010155	putative Mg++ binding site [ion binding]; other site
979556010156	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556010157	nucleotide binding region [chemical binding]; other site
979556010158	ATP-binding site [chemical binding]; other site
979556010159	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
979556010160	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
979556010161	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
979556010162	iron-sulfur cluster [ion binding]; other site
979556010163	[2Fe-2S] cluster binding site [ion binding]; other site
979556010164	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_6; cd07242
979556010165	putative dimer interface [polypeptide binding]; other site
979556010166	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556010167	ligand binding site [chemical binding]; other site
979556010168	Zn binding site [ion binding]; other site
979556010169	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
979556010170	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
979556010171	active site
979556010172	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
979556010173	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
979556010174	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
979556010175	dihydroorotase; Validated; Region: pyrC; PRK09357
979556010176	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
979556010177	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
979556010178	active site
979556010179	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
979556010180	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
979556010181	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
979556010182	catalytic site [active]
979556010183	subunit interface [polypeptide binding]; other site
979556010184	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
979556010185	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
979556010186	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556010187	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
979556010188	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
979556010189	ATP-grasp domain; Region: ATP-grasp_4; cl17255
979556010190	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
979556010191	IMP binding site; other site
979556010192	dimer interface [polypeptide binding]; other site
979556010193	partial ornithine binding site; other site
979556010194	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
979556010195	active site
979556010196	dimer interface [polypeptide binding]; other site
979556010197	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
979556010198	Guanylate kinase; Region: Guanylate_kin; pfam00625
979556010199	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
979556010200	catalytic site [active]
979556010201	G-X2-G-X-G-K; other site
979556010202	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
979556010203	S-adenosylmethionine synthetase; Validated; Region: PRK05250
979556010204	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
979556010205	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
979556010206	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
979556010207	primosome assembly protein PriA; Provisional; Region: PRK14873
979556010208	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
979556010209	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
979556010210	putative active site [active]
979556010211	substrate binding site [chemical binding]; other site
979556010212	putative cosubstrate binding site; other site
979556010213	catalytic site [active]
979556010214	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
979556010215	substrate binding site [chemical binding]; other site
979556010216	16S rRNA methyltransferase B; Provisional; Region: PRK14902
979556010217	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
979556010218	putative RNA binding site [nucleotide binding]; other site
979556010219	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
979556010220	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
979556010221	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
979556010222	substrate binding site [chemical binding]; other site
979556010223	hexamer interface [polypeptide binding]; other site
979556010224	metal binding site [ion binding]; metal-binding site
979556010225	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
979556010226	metal binding site [ion binding]; metal-binding site
979556010227	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
979556010228	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
979556010229	HisG, C-terminal domain; Region: HisG_C; pfam08029
979556010230	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
979556010231	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
979556010232	substrate binding site [chemical binding]; other site
979556010233	glutamase interaction surface [polypeptide binding]; other site
979556010234	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
979556010235	Domain of unknown function (DUF4175); Region: DUF4175; pfam13779
979556010236	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
979556010237	active site
979556010238	ribulose/triose binding site [chemical binding]; other site
979556010239	phosphate binding site [ion binding]; other site
979556010240	substrate (anthranilate) binding pocket [chemical binding]; other site
979556010241	product (indole) binding pocket [chemical binding]; other site
979556010242	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
979556010243	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
979556010244	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556010245	catalytic residue [active]
979556010246	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
979556010247	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
979556010248	substrate binding site [chemical binding]; other site
979556010249	active site
979556010250	catalytic residues [active]
979556010251	heterodimer interface [polypeptide binding]; other site
979556010252	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
979556010253	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
979556010254	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
979556010255	active site
979556010256	dimer interface [polypeptide binding]; other site
979556010257	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
979556010258	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
979556010259	active site
979556010260	FMN binding site [chemical binding]; other site
979556010261	substrate binding site [chemical binding]; other site
979556010262	3Fe-4S cluster binding site [ion binding]; other site
979556010263	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
979556010264	domain interface; other site
979556010265	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
979556010266	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
979556010267	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
979556010268	pyruvate kinase; Provisional; Region: PRK06247
979556010269	domain interfaces; other site
979556010270	active site
979556010271	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
979556010272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556010273	active site
979556010274	phosphorylation site [posttranslational modification]
979556010275	intermolecular recognition site; other site
979556010276	dimerization interface [polypeptide binding]; other site
979556010277	ANTAR domain; Region: ANTAR; pfam03861
979556010278	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
979556010279	CoenzymeA binding site [chemical binding]; other site
979556010280	subunit interaction site [polypeptide binding]; other site
979556010281	PHB binding site; other site
979556010282	5'-3' exonuclease; Region: 53EXOc; smart00475
979556010283	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
979556010284	active site
979556010285	metal binding site 1 [ion binding]; metal-binding site
979556010286	putative 5' ssDNA interaction site; other site
979556010287	metal binding site 3; metal-binding site
979556010288	metal binding site 2 [ion binding]; metal-binding site
979556010289	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
979556010290	putative DNA binding site [nucleotide binding]; other site
979556010291	putative metal binding site [ion binding]; other site
979556010292	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
979556010293	bifunctional 3'-5' exonuclease/DNA polymerase; Provisional; Region: PRK14975
979556010294	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
979556010295	active site
979556010296	DNA binding site [nucleotide binding]
979556010297	catalytic site [active]
979556010298	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
979556010299	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
979556010300	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
979556010301	benzoate transport; Region: 2A0115; TIGR00895
979556010302	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556010303	putative substrate translocation pore; other site
979556010304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
979556010305	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
979556010306	active site
979556010307	catalytic triad [active]
979556010308	oxyanion hole [active]
979556010309	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556010310	NAD(P) binding site [chemical binding]; other site
979556010311	active site
979556010312	Protein of unknown function (DUF2510); Region: DUF2510; pfam10708
979556010313	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
979556010314	Catalytic domain of Protein Kinases; Region: PKc; cd00180
979556010315	active site
979556010316	ATP binding site [chemical binding]; other site
979556010317	substrate binding site [chemical binding]; other site
979556010318	activation loop (A-loop); other site
979556010319	Predicted permeases [General function prediction only]; Region: COG0679
979556010320	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
979556010321	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
979556010322	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
979556010323	short chain dehydrogenase; Provisional; Region: PRK07806
979556010324	NAD(P) binding site [chemical binding]; other site
979556010325	active site
979556010326	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
979556010327	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
979556010328	active site
979556010329	catalytic site [active]
979556010330	Domain of unknown function (DUF4109); Region: DUF4109; pfam13397
979556010331	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
979556010332	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
979556010333	putative active site [active]
979556010334	catalytic triad [active]
979556010335	putative dimer interface [polypeptide binding]; other site
979556010336	DEAD-like helicases superfamily; Region: DEXDc; smart00487
979556010337	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556010338	ATP binding site [chemical binding]; other site
979556010339	putative Mg++ binding site [ion binding]; other site
979556010340	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556010341	nucleotide binding region [chemical binding]; other site
979556010342	ATP-binding site [chemical binding]; other site
979556010343	DSHCT (NUC185) domain; Region: DSHCT; pfam08148
979556010344	Sec-independent protein translocase protein (TatC); Region: TatC; pfam00902
979556010345	mttA/Hcf106 family; Region: MttA_Hcf106; pfam02416
979556010346	WYL domain; Region: WYL; pfam13280
979556010347	Predicted transcriptional regulator [Transcription]; Region: COG2378
979556010348	WYL domain; Region: WYL; pfam13280
979556010349	tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Translation, ribosomal structure and biogenesis]; Region: GCD14; COG2519
979556010350	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
979556010351	S-adenosylmethionine binding site [chemical binding]; other site
979556010352	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
979556010353	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
979556010354	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556010355	motif II; other site
979556010356	PAC2 family; Region: PAC2; pfam09754
979556010357	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554
979556010358	hypothetical protein; Provisional; Region: PRK07906
979556010359	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
979556010360	putative metal binding site [ion binding]; other site
979556010361	oxidase reductase; Provisional; Region: PTZ00273
979556010362	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
979556010363	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
979556010364	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
979556010365	diiron binding motif [ion binding]; other site
979556010366	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_2; cd02433
979556010367	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
979556010368	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556010369	ATP binding site [chemical binding]; other site
979556010370	putative Mg++ binding site [ion binding]; other site
979556010371	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
979556010372	active site
979556010373	catalytic triad [active]
979556010374	oxyanion hole [active]
979556010375	Domain of unknown function (DUF3806); Region: DUF3806; pfam12713
979556010376	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
979556010377	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
979556010378	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
979556010379	cytosine deaminase; Provisional; Region: PRK05985
979556010380	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
979556010381	active site
979556010382	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
979556010383	NAD-dependent deacetylase; Provisional; Region: PRK05333
979556010384	PaaX-like protein; Region: PaaX; pfam07848
979556010385	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
979556010386	salicylyl-CoA 5-hydroxylase; Reviewed; Region: PRK08255
979556010387	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
979556010388	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
979556010389	acyl-activating enzyme (AAE) consensus motif; other site
979556010390	active site
979556010391	AMP binding site [chemical binding]; other site
979556010392	substrate binding site [chemical binding]; other site
979556010393	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
979556010394	Mycothiol maleylpyruvate isomerase N-terminal domain; Region: MDMPI_N; pfam11716
979556010395	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
979556010396	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
979556010397	Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3435
979556010398	Cupin domain; Region: Cupin_2; pfam07883
979556010399	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556010400	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
979556010401	catalytic core [active]
979556010402	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
979556010403	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
979556010404	active site
979556010405	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
979556010406	E3 interaction surface; other site
979556010407	lipoyl attachment site [posttranslational modification]; other site
979556010408	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11857
979556010409	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
979556010410	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
979556010411	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
979556010412	alpha subunit interface [polypeptide binding]; other site
979556010413	TPP binding site [chemical binding]; other site
979556010414	heterodimer interface [polypeptide binding]; other site
979556010415	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
979556010416	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
979556010417	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
979556010418	tetramer interface [polypeptide binding]; other site
979556010419	TPP-binding site [chemical binding]; other site
979556010420	heterodimer interface [polypeptide binding]; other site
979556010421	phosphorylation loop region [posttranslational modification]
979556010422	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
979556010423	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
979556010424	AsnC family; Region: AsnC_trans_reg; pfam01037
979556010425	EamA-like transporter family; Region: EamA; pfam00892
979556010426	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
979556010427	CGNR zinc finger; Region: zf-CGNR; pfam11706
979556010428	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
979556010429	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556010430	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
979556010431	active site
979556010432	catalytic site [active]
979556010433	substrate binding site [chemical binding]; other site
979556010434	Domain of unknown function (DUF222); Region: DUF222; pfam02720
979556010435	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
979556010436	active site
979556010437	Predicted amidohydrolase [General function prediction only]; Region: COG0388
979556010438	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
979556010439	active site
979556010440	catalytic triad [active]
979556010441	dimer interface [polypeptide binding]; other site
979556010442	Serine hydrolase; Region: Ser_hydrolase; pfam06821
979556010443	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556010444	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
979556010445	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
979556010446	putative DNA binding site [nucleotide binding]; other site
979556010447	putative Zn2+ binding site [ion binding]; other site
979556010448	AsnC family; Region: AsnC_trans_reg; pfam01037
979556010449	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
979556010450	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
979556010451	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556010452	Walker A/P-loop; other site
979556010453	ATP binding site [chemical binding]; other site
979556010454	Q-loop/lid; other site
979556010455	ABC transporter signature motif; other site
979556010456	Walker B; other site
979556010457	D-loop; other site
979556010458	H-loop/switch region; other site
979556010459	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
979556010460	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
979556010461	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00844
979556010462	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
979556010463	ligand binding site; other site
979556010464	oligomer interface; other site
979556010465	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
979556010466	dimer interface [polypeptide binding]; other site
979556010467	N-terminal domain interface [polypeptide binding]; other site
979556010468	sulfate 1 binding site; other site
979556010469	S-ribosylhomocysteinase; Provisional; Region: PRK02260
979556010470	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
979556010471	phosphoserine phosphatase SerB; Region: serB; TIGR00338
979556010472	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
979556010473	motif II; other site
979556010474	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
979556010475	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
979556010476	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
979556010477	NAD(P) binding site [chemical binding]; other site
979556010478	active site
979556010479	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
979556010480	Protein of unknown function (DUF3099); Region: DUF3099; pfam11298
979556010481	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
979556010482	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
979556010483	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
979556010484	Walker A/P-loop; other site
979556010485	ATP binding site [chemical binding]; other site
979556010486	Q-loop/lid; other site
979556010487	ABC transporter signature motif; other site
979556010488	Walker B; other site
979556010489	D-loop; other site
979556010490	H-loop/switch region; other site
979556010491	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
979556010492	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
979556010493	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
979556010494	siderophore binding site; other site
979556010495	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
979556010496	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556010497	ABC-ATPase subunit  interface; other site
979556010498	dimer interface [polypeptide binding]; other site
979556010499	putative PBP binding regions; other site
979556010500	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
979556010501	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
979556010502	ABC-ATPase subunit  interface; other site
979556010503	dimer interface [polypeptide binding]; other site
979556010504	putative PBP binding regions; other site
979556010505	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
979556010506	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
979556010507	Walker A/P-loop; other site
979556010508	ATP binding site [chemical binding]; other site
979556010509	Q-loop/lid; other site
979556010510	ABC transporter signature motif; other site
979556010511	Walker B; other site
979556010512	D-loop; other site
979556010513	H-loop/switch region; other site
979556010514	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
979556010515	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
979556010516	FAD binding pocket [chemical binding]; other site
979556010517	FAD binding motif [chemical binding]; other site
979556010518	phosphate binding motif [ion binding]; other site
979556010519	NAD binding pocket [chemical binding]; other site
979556010520	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
979556010521	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
979556010522	pyridoxal 5'-phosphate binding site [chemical binding]; other site
979556010523	homodimer interface [polypeptide binding]; other site
979556010524	catalytic residue [active]
979556010525	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
979556010526	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
979556010527	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
979556010528	Walker A/P-loop; other site
979556010529	ATP binding site [chemical binding]; other site
979556010530	Q-loop/lid; other site
979556010531	ABC transporter signature motif; other site
979556010532	Walker B; other site
979556010533	D-loop; other site
979556010534	H-loop/switch region; other site
979556010535	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
979556010536	[2Fe-2S] cluster binding site [ion binding]; other site
979556010537	FeS assembly protein SufD; Region: sufD; TIGR01981
979556010538	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
979556010539	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
979556010540	FeS assembly protein SufB; Region: sufB; TIGR01980
979556010541	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
979556010542	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
979556010543	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
979556010544	UbiA prenyltransferase family; Region: UbiA; pfam01040
979556010545	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
979556010546	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
979556010547	TPP-binding site [chemical binding]; other site
979556010548	dimer interface [polypeptide binding]; other site
979556010549	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
979556010550	PYR/PP interface [polypeptide binding]; other site
979556010551	dimer interface [polypeptide binding]; other site
979556010552	TPP binding site [chemical binding]; other site
979556010553	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
979556010554	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
979556010555	putative active site [active]
979556010556	transaldolase; Provisional; Region: PRK03903
979556010557	catalytic residue [active]
979556010558	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
979556010559	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
979556010560	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
979556010561	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
979556010562	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
979556010563	Glucose-6-phosphate dehydrogenase subunit; Region: OpcA_G6PD_assem; pfam10128
979556010564	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
979556010565	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
979556010566	putative active site [active]
979556010567	Domain of unknown function (DUF4109); Region: DUF4109; pfam13397
979556010568	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
979556010569	triosephosphate isomerase; Provisional; Region: PRK14567
979556010570	substrate binding site [chemical binding]; other site
979556010571	dimer interface [polypeptide binding]; other site
979556010572	catalytic triad [active]
979556010573	Phosphoglycerate kinase; Region: PGK; pfam00162
979556010574	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
979556010575	substrate binding site [chemical binding]; other site
979556010576	hinge regions; other site
979556010577	ADP binding site [chemical binding]; other site
979556010578	catalytic site [active]
979556010579	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
979556010580	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
979556010581	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
979556010582	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
979556010583	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
979556010584	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
979556010585	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
979556010586	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
979556010587	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
979556010588	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
979556010589	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
979556010590	GIY-YIG motif/motif A; other site
979556010591	active site
979556010592	catalytic site [active]
979556010593	putative DNA binding site [nucleotide binding]; other site
979556010594	metal binding site [ion binding]; metal-binding site
979556010595	UvrB/uvrC motif; Region: UVR; pfam02151
979556010596	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
979556010597	Helix-hairpin-helix motif; Region: HHH; pfam00633
979556010598	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
979556010599	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
979556010600	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
979556010601	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
979556010602	MarR family; Region: MarR; pfam01047
979556010603	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
979556010604	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
979556010605	excinuclease ABC subunit B; Provisional; Region: PRK05298
979556010606	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
979556010607	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
979556010608	nucleotide binding region [chemical binding]; other site
979556010609	ATP-binding site [chemical binding]; other site
979556010610	Ultra-violet resistance protein B; Region: UvrB; pfam12344
979556010611	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
979556010612	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
979556010613	CoA-binding site [chemical binding]; other site
979556010614	ATP-binding [chemical binding]; other site
979556010615	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
979556010616	Response regulator receiver domain; Region: Response_reg; pfam00072
979556010617	active site
979556010618	phosphorylation site [posttranslational modification]
979556010619	intermolecular recognition site; other site
979556010620	dimerization interface [polypeptide binding]; other site
979556010621	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
979556010622	metal binding site [ion binding]; metal-binding site
979556010623	active site
979556010624	I-site; other site
979556010625	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
979556010626	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
979556010627	dimer interface [polypeptide binding]; other site
979556010628	phosphorylation site [posttranslational modification]
979556010629	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
979556010630	ATP binding site [chemical binding]; other site
979556010631	Mg2+ binding site [ion binding]; other site
979556010632	G-X-G motif; other site
979556010633	T5orf172 domain; Region: T5orf172; pfam10544
979556010634	trehalose synthase, Pseudomonas stutzeri type; Region: TreS_stutzeri; TIGR02455