-- dump date   	20140619_150718
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1124991000001	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; cl00614
1124991000002	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1124991000003	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1124991000004	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1124991000005	substrate binding site [chemical binding]; other site
1124991000006	ATP binding site [chemical binding]; other site
1124991000007	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1124991000008	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991000009	dimer interface [polypeptide binding]; other site
1124991000010	putative CheW interface [polypeptide binding]; other site
1124991000011	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1124991000012	low affinity gluconate transporter; Provisional; Region: PRK10472
1124991000013	gluconate transporter; Region: gntP; TIGR00791
1124991000014	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1124991000015	AAA domain; Region: AAA_33; pfam13671
1124991000016	ATP-binding site [chemical binding]; other site
1124991000017	Gluconate-6-phosphate binding site [chemical binding]; other site
1124991000018	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1124991000019	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991000020	DNA binding site [nucleotide binding]
1124991000021	domain linker motif; other site
1124991000022	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1124991000023	putative ligand binding site [chemical binding]; other site
1124991000024	putative dimerization interface [polypeptide binding]; other site
1124991000025	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
1124991000026	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1124991000027	putative metal binding site [ion binding]; other site
1124991000028	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1124991000029	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991000030	ABC-ATPase subunit  interface; other site
1124991000031	dimer interface [polypeptide binding]; other site
1124991000032	putative PBP binding regions; other site
1124991000033	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991000034	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
1124991000035	Walker A/P-loop; other site
1124991000036	ATP binding site [chemical binding]; other site
1124991000037	Q-loop/lid; other site
1124991000038	ABC transporter signature motif; other site
1124991000039	Walker B; other site
1124991000040	D-loop; other site
1124991000041	H-loop/switch region; other site
1124991000042	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991000043	S-adenosylmethionine binding site [chemical binding]; other site
1124991000044	molybdenum transport protein ModD; Provisional; Region: PRK06096
1124991000045	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
1124991000046	dimerization interface [polypeptide binding]; other site
1124991000047	active site
1124991000048	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1124991000049	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991000050	N-terminal plug; other site
1124991000051	ligand-binding site [chemical binding]; other site
1124991000052	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1124991000053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991000054	putative substrate translocation pore; other site
1124991000055	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1124991000056	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991000057	homodimer interface [polypeptide binding]; other site
1124991000058	substrate-cofactor binding pocket; other site
1124991000059	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991000060	catalytic residue [active]
1124991000061	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1124991000062	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1124991000063	DNA binding residues [nucleotide binding]
1124991000064	drug binding residues [chemical binding]; other site
1124991000065	dimer interface [polypeptide binding]; other site
1124991000066	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1124991000067	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1124991000068	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991000069	LemA family; Region: LemA; cl00742
1124991000070	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1124991000071	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1124991000072	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK06084
1124991000073	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991000074	homodimer interface [polypeptide binding]; other site
1124991000075	substrate-cofactor binding pocket; other site
1124991000076	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991000077	catalytic residue [active]
1124991000078	Invasion plasmid antigen IpaD; Region: IpaD; cl05827
1124991000079	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1124991000080	binding surface
1124991000081	TPR motif; other site
1124991000082	type III secretion protein, YscU/HrpY family; Region: FlhB_rel_III; TIGR01404
1124991000083	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
1124991000084	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1124991000085	FliP family; Region: FliP; cl00593
1124991000086	type III secretion system apparatus protein YscQ/HrcQ; Region: SpaO_YscQ; TIGR02551
1124991000087	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1124991000088	ATP synthase SpaL; Validated; Region: PRK08149
1124991000089	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1124991000090	Walker A motif; other site
1124991000091	ATP binding site [chemical binding]; other site
1124991000092	Walker B motif; other site
1124991000093	Invasion protein B family; Region: Invas_SpaK; cl04129
1124991000094	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
1124991000095	type III secretion system protein InvA; Provisional; Region: PRK15337
1124991000096	HrpJ-like domain; Region: HrpJ; cl15454
1124991000097	type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516
1124991000098	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1124991000099	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1124991000100	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1124991000101	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1124991000102	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
1124991000103	invasion protein OrgB; Provisional; Region: PRK15322
1124991000104	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991000105	non-specific DNA binding site [nucleotide binding]; other site
1124991000106	salt bridge; other site
1124991000107	sequence-specific DNA binding site [nucleotide binding]; other site
1124991000108	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1124991000109	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1124991000110	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1124991000111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991000112	dimer interface [polypeptide binding]; other site
1124991000113	conserved gate region; other site
1124991000114	putative PBP binding loops; other site
1124991000115	ABC-ATPase subunit interface; other site
1124991000116	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1124991000117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991000118	dimer interface [polypeptide binding]; other site
1124991000119	conserved gate region; other site
1124991000120	putative PBP binding loops; other site
1124991000121	ABC-ATPase subunit interface; other site
1124991000122	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1124991000123	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1124991000124	Walker A/P-loop; other site
1124991000125	ATP binding site [chemical binding]; other site
1124991000126	Q-loop/lid; other site
1124991000127	ABC transporter signature motif; other site
1124991000128	Walker B; other site
1124991000129	D-loop; other site
1124991000130	H-loop/switch region; other site
1124991000131	TOBE domain; Region: TOBE_2; pfam08402
1124991000132	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1124991000133	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1124991000134	dimer interface [polypeptide binding]; other site
1124991000135	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1124991000136	catalytic triad [active]
1124991000137	peroxidatic and resolving cysteines [active]
1124991000138	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1124991000139	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1124991000140	catalytic residue [active]
1124991000141	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1124991000142	catalytic residues [active]
1124991000143	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991000144	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991000145	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1124991000146	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991000147	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1124991000148	substrate binding pocket [chemical binding]; other site
1124991000149	dimerization interface [polypeptide binding]; other site
1124991000150	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1124991000151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991000152	putative substrate translocation pore; other site
1124991000153	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1124991000154	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991000155	non-specific DNA binding site [nucleotide binding]; other site
1124991000156	salt bridge; other site
1124991000157	sequence-specific DNA binding site [nucleotide binding]; other site
1124991000158	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1124991000159	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000160	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000161	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000162	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000163	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000164	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000165	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000166	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000167	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000168	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000169	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000170	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000171	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000172	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000173	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000174	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000175	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000176	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991000177	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1124991000178	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991000179	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991000180	non-specific DNA binding site [nucleotide binding]; other site
1124991000181	salt bridge; other site
1124991000182	sequence-specific DNA binding site [nucleotide binding]; other site
1124991000183	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1124991000184	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1124991000185	putative active site [active]
1124991000186	catalytic site [active]
1124991000187	putative metal binding site [ion binding]; other site
1124991000188	transcriptional regulator NarL; Provisional; Region: PRK10651
1124991000189	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991000190	active site
1124991000191	phosphorylation site [posttranslational modification]
1124991000192	intermolecular recognition site; other site
1124991000193	dimerization interface [polypeptide binding]; other site
1124991000194	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991000195	DNA binding residues [nucleotide binding]
1124991000196	dimerization interface [polypeptide binding]; other site
1124991000197	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1124991000198	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1124991000199	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991000200	dimerization interface [polypeptide binding]; other site
1124991000201	Histidine kinase; Region: HisKA_3; pfam07730
1124991000202	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991000203	ATP binding site [chemical binding]; other site
1124991000204	Mg2+ binding site [ion binding]; other site
1124991000205	G-X-G motif; other site
1124991000206	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1124991000207	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1124991000208	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1124991000209	[4Fe-4S] binding site [ion binding]; other site
1124991000210	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991000211	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991000212	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991000213	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1124991000214	molybdopterin cofactor binding site; other site
1124991000215	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1124991000216	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1124991000217	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1124991000218	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991000219	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991000220	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991000221	putative effector binding pocket; other site
1124991000222	dimerization interface [polypeptide binding]; other site
1124991000223	alanine-tRNA ligase; Region: PLN02961
1124991000224	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1124991000225	LysE type translocator; Region: LysE; cl00565
1124991000226	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991000227	non-specific DNA binding site [nucleotide binding]; other site
1124991000228	salt bridge; other site
1124991000229	sequence-specific DNA binding site [nucleotide binding]; other site
1124991000230	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
1124991000231	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1124991000232	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1124991000233	NAD(P) binding site [chemical binding]; other site
1124991000234	catalytic residues [active]
1124991000235	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991000236	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1124991000237	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991000238	DNA-binding site [nucleotide binding]; DNA binding site
1124991000239	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991000240	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991000241	homodimer interface [polypeptide binding]; other site
1124991000242	catalytic residue [active]
1124991000243	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991000244	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991000245	Coenzyme A binding pocket [chemical binding]; other site
1124991000246	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1124991000247	M20 Peptidase Aminoacylase 1-like protein 2, amidohydrolase family; Region: M20_Acy1L2_like_2; cd09849
1124991000248	metal binding site [ion binding]; metal-binding site
1124991000249	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
1124991000250	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991000251	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1124991000252	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991000253	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991000254	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991000255	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991000256	Fimbrial protein; Region: Fimbrial; pfam00419
1124991000257	Fimbrial protein; Region: Fimbrial; pfam00419
1124991000258	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991000259	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1124991000260	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991000261	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1124991000262	putative dimerization interface [polypeptide binding]; other site
1124991000263	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1124991000264	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1124991000265	intersubunit interface [polypeptide binding]; other site
1124991000266	active site
1124991000267	zinc binding site [ion binding]; other site
1124991000268	Na+ binding site [ion binding]; other site
1124991000269	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1124991000270	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1124991000271	substrate binding site [chemical binding]; other site
1124991000272	ATP binding site [chemical binding]; other site
1124991000273	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1124991000274	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1124991000275	active site
1124991000276	P-loop; other site
1124991000277	phosphorylation site [posttranslational modification]
1124991000278	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1124991000279	active site
1124991000280	phosphorylation site [posttranslational modification]
1124991000281	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1124991000282	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991000283	intersubunit interface [polypeptide binding]; other site
1124991000284	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1124991000285	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991000286	N-terminal plug; other site
1124991000287	ligand-binding site [chemical binding]; other site
1124991000288	EamA-like transporter family; Region: EamA; pfam00892
1124991000289	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1124991000290	EamA-like transporter family; Region: EamA; pfam00892
1124991000291	allantoate amidohydrolase; Reviewed; Region: PRK12890
1124991000292	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1124991000293	active site
1124991000294	metal binding site [ion binding]; metal-binding site
1124991000295	dimer interface [polypeptide binding]; other site
1124991000296	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1124991000297	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1124991000298	cofactor binding site; other site
1124991000299	DNA binding site [nucleotide binding]
1124991000300	substrate interaction site [chemical binding]; other site
1124991000301	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1124991000302	additional DNA contacts [nucleotide binding]; other site
1124991000303	mismatch recognition site; other site
1124991000304	active site
1124991000305	zinc binding site [ion binding]; other site
1124991000306	DNA intercalation site [nucleotide binding]; other site
1124991000307	HTH domain; Region: HTH_11; pfam08279
1124991000308	Predicted transcriptional regulator [Transcription]; Region: COG2378
1124991000309	WYL domain; Region: WYL; pfam13280
1124991000310	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1124991000311	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1124991000312	putative C-terminal domain interface [polypeptide binding]; other site
1124991000313	putative GSH binding site (G-site) [chemical binding]; other site
1124991000314	putative dimer interface [polypeptide binding]; other site
1124991000315	C-terminal, alpha helical domain of an unknown subfamily 8 of Glutathione S-transferases; Region: GST_C_8; cd03207
1124991000316	dimer interface [polypeptide binding]; other site
1124991000317	N-terminal domain interface [polypeptide binding]; other site
1124991000318	putative substrate binding pocket (H-site) [chemical binding]; other site
1124991000319	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1124991000320	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991000321	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991000322	non-specific DNA binding site [nucleotide binding]; other site
1124991000323	salt bridge; other site
1124991000324	sequence-specific DNA binding site [nucleotide binding]; other site
1124991000325	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991000326	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1124991000327	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1124991000328	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1124991000329	HNH endonuclease; Region: HNH_2; pfam13391
1124991000330	HNH endonuclease; Region: HNH_2; pfam13391
1124991000331	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1124991000332	DNA-binding interface [nucleotide binding]; DNA binding site
1124991000333	Winged helix-turn helix; Region: HTH_29; pfam13551
1124991000334	putative transposase OrfB; Reviewed; Region: PHA02517
1124991000335	HTH-like domain; Region: HTH_21; pfam13276
1124991000336	Integrase core domain; Region: rve; pfam00665
1124991000337	Integrase core domain; Region: rve_3; pfam13683
1124991000338	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
1124991000339	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1124991000340	active site
1124991000341	catalytic triad [active]
1124991000342	dimer interface [polypeptide binding]; other site
1124991000343	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1124991000344	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
1124991000345	putative active site [active]
1124991000346	putative NTP binding site [chemical binding]; other site
1124991000347	putative nucleic acid binding site [nucleotide binding]; other site
1124991000348	integrase; Provisional; Region: PRK09692
1124991000349	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1124991000350	active site
1124991000351	Int/Topo IB signature motif; other site
1124991000352	Predicted transcriptional regulator [Transcription]; Region: COG2378
1124991000353	WYL domain; Region: WYL; pfam13280
1124991000354	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1124991000355	Antirestriction protein; Region: Antirestrict; pfam03230
1124991000356	Predicted GTPase [General function prediction only]; Region: COG3596
1124991000357	YfjP GTPase; Region: YfjP; cd11383
1124991000358	G1 box; other site
1124991000359	GTP/Mg2+ binding site [chemical binding]; other site
1124991000360	Switch I region; other site
1124991000361	G2 box; other site
1124991000362	Switch II region; other site
1124991000363	G3 box; other site
1124991000364	G4 box; other site
1124991000365	G5 box; other site
1124991000366	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1124991000367	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1124991000368	DNA binding domain, excisionase family; Region: excise; TIGR01764
1124991000369	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483
1124991000370	Protein of unknown function (DUF499); Region: DUF499; pfam04465
1124991000371	Protein of unknown function (DUF3780); Region: DUF3780; pfam12635
1124991000372	Protein of unknown function (DUF1156); Region: DUF1156; pfam06634
1124991000373	Adenine-specific DNA methylase containing a Zn-ribbon [DNA replication, recombination, and repair]; Region: COG1743
1124991000374	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1124991000375	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1124991000376	PLD-like domain; Region: PLDc_2; pfam13091
1124991000377	putative active site [active]
1124991000378	catalytic site [active]
1124991000379	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1124991000380	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991000381	ATP binding site [chemical binding]; other site
1124991000382	putative Mg++ binding site [ion binding]; other site
1124991000383	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991000384	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1124991000385	nucleotide binding region [chemical binding]; other site
1124991000386	ATP-binding site [chemical binding]; other site
1124991000387	Antirestriction protein (ArdA); Region: ArdA; cl01953
1124991000388	integrase; Provisional; Region: PRK09692
1124991000389	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1124991000390	active site
1124991000391	Int/Topo IB signature motif; other site
1124991000392	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1124991000393	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1124991000394	hypothetical protein; Reviewed; Region: PRK09588
1124991000395	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1124991000396	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1124991000397	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1124991000398	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991000399	Walker A motif; other site
1124991000400	ATP binding site [chemical binding]; other site
1124991000401	Walker B motif; other site
1124991000402	arginine finger; other site
1124991000403	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1124991000404	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1124991000405	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1124991000406	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1124991000407	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1124991000408	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1124991000409	interface (dimer of trimers) [polypeptide binding]; other site
1124991000410	Substrate-binding/catalytic site; other site
1124991000411	Zn-binding sites [ion binding]; other site
1124991000412	DNA polymerase III subunit chi; Validated; Region: PRK05728
1124991000413	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1124991000414	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1124991000415	HIGH motif; other site
1124991000416	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1124991000417	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1124991000418	active site
1124991000419	KMSKS motif; other site
1124991000420	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1124991000421	tRNA binding surface [nucleotide binding]; other site
1124991000422	anticodon binding site; other site
1124991000423	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1124991000424	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991000425	Coenzyme A binding pocket [chemical binding]; other site
1124991000426	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991000427	RNase E inhibitor protein; Provisional; Region: PRK11191
1124991000428	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1124991000429	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1124991000430	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1124991000431	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1124991000432	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1124991000433	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1124991000434	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1124991000435	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1124991000436	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1124991000437	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1124991000438	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1124991000439	homotrimer interaction site [polypeptide binding]; other site
1124991000440	putative active site [active]
1124991000441	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991000442	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991000443	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1124991000444	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1124991000445	ATP cone domain; Region: ATP-cone; pfam03477
1124991000446	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1124991000447	effector binding site; other site
1124991000448	active site
1124991000449	Zn binding site [ion binding]; other site
1124991000450	glycine loop; other site
1124991000451	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1124991000452	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991000453	FeS/SAM binding site; other site
1124991000454	hypothetical protein; Provisional; Region: PRK03467
1124991000455	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1124991000456	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1124991000457	GIY-YIG motif/motif A; other site
1124991000458	putative active site [active]
1124991000459	putative metal binding site [ion binding]; other site
1124991000460	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991000461	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991000462	Coenzyme A binding pocket [chemical binding]; other site
1124991000463	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1124991000464	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1124991000465	Peptidase family U32; Region: Peptidase_U32; pfam01136
1124991000466	putative protease; Provisional; Region: PRK15447
1124991000467	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1124991000468	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
1124991000469	homotrimer interaction site [polypeptide binding]; other site
1124991000470	putative active site [active]
1124991000471	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1124991000472	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991000473	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991000474	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1124991000475	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991000476	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991000477	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1124991000478	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1124991000479	GAF domain; Region: GAF; pfam01590
1124991000480	Histidine kinase; Region: His_kinase; pfam06580
1124991000481	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991000482	ATP binding site [chemical binding]; other site
1124991000483	Mg2+ binding site [ion binding]; other site
1124991000484	G-X-G motif; other site
1124991000485	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1124991000486	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991000487	active site
1124991000488	phosphorylation site [posttranslational modification]
1124991000489	intermolecular recognition site; other site
1124991000490	dimerization interface [polypeptide binding]; other site
1124991000491	LytTr DNA-binding domain; Region: LytTR; pfam04397
1124991000492	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
1124991000493	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1124991000494	ATP binding site [chemical binding]; other site
1124991000495	Mg++ binding site [ion binding]; other site
1124991000496	motif III; other site
1124991000497	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991000498	nucleotide binding region [chemical binding]; other site
1124991000499	ATP-binding site [chemical binding]; other site
1124991000500	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1124991000501	putative RNA binding site [nucleotide binding]; other site
1124991000502	lipoprotein NlpI; Provisional; Region: PRK11189
1124991000503	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1124991000504	binding surface
1124991000505	TPR motif; other site
1124991000506	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1124991000507	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1124991000508	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1124991000509	RNase E interface [polypeptide binding]; other site
1124991000510	trimer interface [polypeptide binding]; other site
1124991000511	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1124991000512	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1124991000513	RNase E interface [polypeptide binding]; other site
1124991000514	trimer interface [polypeptide binding]; other site
1124991000515	active site
1124991000516	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1124991000517	putative nucleic acid binding region [nucleotide binding]; other site
1124991000518	G-X-X-G motif; other site
1124991000519	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1124991000520	RNA binding site [nucleotide binding]; other site
1124991000521	domain interface; other site
1124991000522	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1124991000523	16S/18S rRNA binding site [nucleotide binding]; other site
1124991000524	S13e-L30e interaction site [polypeptide binding]; other site
1124991000525	25S rRNA binding site [nucleotide binding]; other site
1124991000526	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1124991000527	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1124991000528	RNA binding site [nucleotide binding]; other site
1124991000529	active site
1124991000530	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1124991000531	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1124991000532	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1124991000533	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1124991000534	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1124991000535	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1124991000536	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1124991000537	G1 box; other site
1124991000538	putative GEF interaction site [polypeptide binding]; other site
1124991000539	GTP/Mg2+ binding site [chemical binding]; other site
1124991000540	Switch I region; other site
1124991000541	G2 box; other site
1124991000542	G3 box; other site
1124991000543	Switch II region; other site
1124991000544	G4 box; other site
1124991000545	G5 box; other site
1124991000546	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1124991000547	Translation-initiation factor 2; Region: IF-2; pfam11987
1124991000548	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1124991000549	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1124991000550	NusA N-terminal domain; Region: NusA_N; pfam08529
1124991000551	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1124991000552	RNA binding site [nucleotide binding]; other site
1124991000553	homodimer interface [polypeptide binding]; other site
1124991000554	NusA-like KH domain; Region: KH_5; pfam13184
1124991000555	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1124991000556	G-X-X-G motif; other site
1124991000557	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1124991000558	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1124991000559	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1124991000560	Sm and related proteins; Region: Sm_like; cl00259
1124991000561	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1124991000562	putative oligomer interface [polypeptide binding]; other site
1124991000563	putative RNA binding site [nucleotide binding]; other site
1124991000564	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1124991000565	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1124991000566	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1124991000567	active site
1124991000568	substrate binding site [chemical binding]; other site
1124991000569	metal binding site [ion binding]; metal-binding site
1124991000570	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1124991000571	dihydropteroate synthase; Region: DHPS; TIGR01496
1124991000572	substrate binding pocket [chemical binding]; other site
1124991000573	dimer interface [polypeptide binding]; other site
1124991000574	inhibitor binding site; inhibition site
1124991000575	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1124991000576	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991000577	Walker A motif; other site
1124991000578	ATP binding site [chemical binding]; other site
1124991000579	Walker B motif; other site
1124991000580	arginine finger; other site
1124991000581	Peptidase family M41; Region: Peptidase_M41; pfam01434
1124991000582	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1124991000583	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991000584	S-adenosylmethionine binding site [chemical binding]; other site
1124991000585	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
1124991000586	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1124991000587	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1124991000588	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1124991000589	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1124991000590	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1124991000591	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1124991000592	GTP1/OBG; Region: GTP1_OBG; pfam01018
1124991000593	Obg GTPase; Region: Obg; cd01898
1124991000594	G1 box; other site
1124991000595	GTP/Mg2+ binding site [chemical binding]; other site
1124991000596	Switch I region; other site
1124991000597	G2 box; other site
1124991000598	G3 box; other site
1124991000599	Switch II region; other site
1124991000600	G4 box; other site
1124991000601	G5 box; other site
1124991000602	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1124991000603	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1124991000604	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1124991000605	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1124991000606	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1124991000607	substrate binding pocket [chemical binding]; other site
1124991000608	chain length determination region; other site
1124991000609	substrate-Mg2+ binding site; other site
1124991000610	catalytic residues [active]
1124991000611	aspartate-rich region 1; other site
1124991000612	active site lid residues [active]
1124991000613	aspartate-rich region 2; other site
1124991000614	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1124991000615	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1124991000616	malate dehydrogenase; Provisional; Region: PRK05086
1124991000617	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1124991000618	NAD binding site [chemical binding]; other site
1124991000619	dimerization interface [polypeptide binding]; other site
1124991000620	Substrate binding site [chemical binding]; other site
1124991000621	arginine repressor; Provisional; Region: PRK05066
1124991000622	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1124991000623	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1124991000624	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1124991000625	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1124991000626	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991000627	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991000628	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1124991000629	AMP binding site [chemical binding]; other site
1124991000630	metal binding site [ion binding]; metal-binding site
1124991000631	active site
1124991000632	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1124991000633	dimer interface [polypeptide binding]; other site
1124991000634	substrate binding site [chemical binding]; other site
1124991000635	metal binding sites [ion binding]; metal-binding site
1124991000636	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1124991000637	putative active site pocket [active]
1124991000638	dimerization interface [polypeptide binding]; other site
1124991000639	putative catalytic residue [active]
1124991000640	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1124991000641	Family of unknown function (DUF490); Region: DUF490; pfam04357
1124991000642	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1124991000643	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1124991000644	Surface antigen; Region: Bac_surface_Ag; pfam01103
1124991000645	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1124991000646	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1124991000647	Domain of unknown function DUF21; Region: DUF21; pfam01595
1124991000648	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1124991000649	Transporter associated domain; Region: CorC_HlyC; smart01091
1124991000650	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1124991000651	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1124991000652	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1124991000653	active site
1124991000654	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1124991000655	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1124991000656	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1124991000657	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1124991000658	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1124991000659	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1124991000660	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1124991000661	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1124991000662	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1124991000663	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1124991000664	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1124991000665	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1124991000666	exoribonuclease R; Provisional; Region: PRK11642
1124991000667	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1124991000668	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1124991000669	RNB domain; Region: RNB; pfam00773
1124991000670	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1124991000671	RNA binding site [nucleotide binding]; other site
1124991000672	transcriptional repressor NsrR; Provisional; Region: PRK11014
1124991000673	Predicted transcriptional regulator [Transcription]; Region: COG1959
1124991000674	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1124991000675	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1124991000676	GDP-binding site [chemical binding]; other site
1124991000677	ACT binding site; other site
1124991000678	IMP binding site; other site
1124991000679	FtsH protease regulator HflC; Provisional; Region: PRK11029
1124991000680	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1124991000681	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1124991000682	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1124991000683	HflK protein; Region: hflK; TIGR01933
1124991000684	GTPase HflX; Provisional; Region: PRK11058
1124991000685	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1124991000686	HflX GTPase family; Region: HflX; cd01878
1124991000687	G1 box; other site
1124991000688	GTP/Mg2+ binding site [chemical binding]; other site
1124991000689	Switch I region; other site
1124991000690	G2 box; other site
1124991000691	G3 box; other site
1124991000692	Switch II region; other site
1124991000693	G4 box; other site
1124991000694	G5 box; other site
1124991000695	bacterial Hfq-like; Region: Hfq; cd01716
1124991000696	hexamer interface [polypeptide binding]; other site
1124991000697	Sm1 motif; other site
1124991000698	RNA binding site [nucleotide binding]; other site
1124991000699	Sm2 motif; other site
1124991000700	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1124991000701	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1124991000702	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1124991000703	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991000704	ATP binding site [chemical binding]; other site
1124991000705	Mg2+ binding site [ion binding]; other site
1124991000706	G-X-G motif; other site
1124991000707	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1124991000708	ATP binding site [chemical binding]; other site
1124991000709	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1124991000710	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1124991000711	AMIN domain; Region: AMIN; pfam11741
1124991000712	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1124991000713	active site
1124991000714	metal binding site [ion binding]; metal-binding site
1124991000715	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1124991000716	epoxyqueuosine reductase; Region: TIGR00276
1124991000717	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1124991000718	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1124991000719	catalytic site [active]
1124991000720	putative active site [active]
1124991000721	putative substrate binding site [chemical binding]; other site
1124991000722	dimer interface [polypeptide binding]; other site
1124991000723	GTPase RsgA; Reviewed; Region: PRK12288
1124991000724	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1124991000725	RNA binding site [nucleotide binding]; other site
1124991000726	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1124991000727	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1124991000728	GTP/Mg2+ binding site [chemical binding]; other site
1124991000729	G4 box; other site
1124991000730	G5 box; other site
1124991000731	G1 box; other site
1124991000732	Switch I region; other site
1124991000733	G2 box; other site
1124991000734	G3 box; other site
1124991000735	Switch II region; other site
1124991000736	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1124991000737	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1124991000738	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1124991000739	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991000740	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991000741	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1124991000742	putative hydrolase; Provisional; Region: PRK10976
1124991000743	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991000744	active site
1124991000745	motif I; other site
1124991000746	motif II; other site
1124991000747	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991000748	lysophospholipase L2; Provisional; Region: PRK10749
1124991000749	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1124991000750	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1124991000751	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991000752	ATP binding site [chemical binding]; other site
1124991000753	putative Mg++ binding site [ion binding]; other site
1124991000754	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991000755	nucleotide binding region [chemical binding]; other site
1124991000756	ATP-binding site [chemical binding]; other site
1124991000757	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1124991000758	HRDC domain; Region: HRDC; pfam00570
1124991000759	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1124991000760	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1124991000761	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1124991000762	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1124991000763	Cl binding site [ion binding]; other site
1124991000764	oligomer interface [polypeptide binding]; other site
1124991000765	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1124991000766	Part of AAA domain; Region: AAA_19; pfam13245
1124991000767	Family description; Region: UvrD_C_2; pfam13538
1124991000768	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1124991000769	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991000770	motif II; other site
1124991000771	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1124991000772	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991000773	active site
1124991000774	DNA binding site [nucleotide binding]
1124991000775	Int/Topo IB signature motif; other site
1124991000776	Protein of unknown function, DUF484; Region: DUF484; cl17449
1124991000777	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1124991000778	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1124991000779	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1124991000780	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
1124991000781	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1124991000782	putative iron binding site [ion binding]; other site
1124991000783	adenylate cyclase; Provisional; Region: cyaA; PRK09450
1124991000784	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1124991000785	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1124991000786	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1124991000787	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1124991000788	domain interfaces; other site
1124991000789	active site
1124991000790	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1124991000791	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1124991000792	active site
1124991000793	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1124991000794	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1124991000795	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1124991000796	HemY protein N-terminus; Region: HemY_N; pfam07219
1124991000797	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1124991000798	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1124991000799	putative common antigen polymerase; Provisional; Region: PRK02975
1124991000800	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1124991000801	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1124991000802	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1124991000803	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1124991000804	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1124991000805	inhibitor-cofactor binding pocket; inhibition site
1124991000806	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991000807	catalytic residue [active]
1124991000808	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1124991000809	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991000810	Coenzyme A binding pocket [chemical binding]; other site
1124991000811	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1124991000812	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1124991000813	substrate binding site; other site
1124991000814	tetramer interface; other site
1124991000815	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1124991000816	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1124991000817	NAD binding site [chemical binding]; other site
1124991000818	substrate binding site [chemical binding]; other site
1124991000819	homodimer interface [polypeptide binding]; other site
1124991000820	active site
1124991000821	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1124991000822	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1124991000823	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1124991000824	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1124991000825	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1124991000826	active site
1124991000827	homodimer interface [polypeptide binding]; other site
1124991000828	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1124991000829	Chain length determinant protein; Region: Wzz; pfam02706
1124991000830	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1124991000831	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1124991000832	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1124991000833	Mg++ binding site [ion binding]; other site
1124991000834	putative catalytic motif [active]
1124991000835	substrate binding site [chemical binding]; other site
1124991000836	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1124991000837	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1124991000838	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1124991000839	RNA binding site [nucleotide binding]; other site
1124991000840	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1124991000841	multimer interface [polypeptide binding]; other site
1124991000842	Walker A motif; other site
1124991000843	ATP binding site [chemical binding]; other site
1124991000844	Walker B motif; other site
1124991000845	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1124991000846	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1124991000847	catalytic residues [active]
1124991000848	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1124991000849	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1124991000850	ATP binding site [chemical binding]; other site
1124991000851	Mg++ binding site [ion binding]; other site
1124991000852	motif III; other site
1124991000853	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991000854	nucleotide binding region [chemical binding]; other site
1124991000855	ATP-binding site [chemical binding]; other site
1124991000856	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1124991000857	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1124991000858	nucleotide binding site [chemical binding]; other site
1124991000859	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1124991000860	Part of AAA domain; Region: AAA_19; pfam13245
1124991000861	Family description; Region: UvrD_C_2; pfam13538
1124991000862	ketol-acid reductoisomerase; Validated; Region: PRK05225
1124991000863	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1124991000864	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1124991000865	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1124991000866	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991000867	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1124991000868	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1124991000869	putative dimerization interface [polypeptide binding]; other site
1124991000870	threonine dehydratase; Reviewed; Region: PRK09224
1124991000871	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1124991000872	tetramer interface [polypeptide binding]; other site
1124991000873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991000874	catalytic residue [active]
1124991000875	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1124991000876	putative Ile/Val binding site [chemical binding]; other site
1124991000877	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1124991000878	putative Ile/Val binding site [chemical binding]; other site
1124991000879	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1124991000880	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1124991000881	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1124991000882	homodimer interface [polypeptide binding]; other site
1124991000883	substrate-cofactor binding pocket; other site
1124991000884	catalytic residue [active]
1124991000885	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1124991000886	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1124991000887	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1124991000888	PYR/PP interface [polypeptide binding]; other site
1124991000889	dimer interface [polypeptide binding]; other site
1124991000890	TPP binding site [chemical binding]; other site
1124991000891	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991000892	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1124991000893	TPP-binding site [chemical binding]; other site
1124991000894	dimer interface [polypeptide binding]; other site
1124991000895	putative ATP-dependent protease; Provisional; Region: PRK09862
1124991000896	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1124991000897	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1124991000898	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1124991000899	hypothetical protein; Provisional; Region: PRK11027
1124991000900	transcriptional regulator HdfR; Provisional; Region: PRK03601
1124991000901	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991000902	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1124991000903	dimerization interface [polypeptide binding]; other site
1124991000904	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1124991000905	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1124991000906	trimer interface [polypeptide binding]; other site
1124991000907	putative metal binding site [ion binding]; other site
1124991000908	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1124991000909	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1124991000910	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1124991000911	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1124991000912	shikimate binding site; other site
1124991000913	NAD(P) binding site [chemical binding]; other site
1124991000914	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1124991000915	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1124991000916	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1124991000917	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1124991000918	hypothetical protein; Provisional; Region: PRK10736
1124991000919	DNA protecting protein DprA; Region: dprA; TIGR00732
1124991000920	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1124991000921	active site
1124991000922	catalytic residues [active]
1124991000923	metal binding site [ion binding]; metal-binding site
1124991000924	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1124991000925	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1124991000926	putative active site [active]
1124991000927	substrate binding site [chemical binding]; other site
1124991000928	putative cosubstrate binding site; other site
1124991000929	catalytic site [active]
1124991000930	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1124991000931	substrate binding site [chemical binding]; other site
1124991000932	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1124991000933	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1124991000934	putative RNA binding site [nucleotide binding]; other site
1124991000935	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991000936	S-adenosylmethionine binding site [chemical binding]; other site
1124991000937	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1124991000938	TrkA-N domain; Region: TrkA_N; pfam02254
1124991000939	TrkA-C domain; Region: TrkA_C; pfam02080
1124991000940	TrkA-N domain; Region: TrkA_N; pfam02254
1124991000941	TrkA-C domain; Region: TrkA_C; pfam02080
1124991000942	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1124991000943	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1124991000944	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1124991000945	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1124991000946	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1124991000947	DNA binding residues [nucleotide binding]
1124991000948	dimer interface [polypeptide binding]; other site
1124991000949	metal binding site [ion binding]; metal-binding site
1124991000950	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1124991000951	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1124991000952	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1124991000953	alphaNTD homodimer interface [polypeptide binding]; other site
1124991000954	alphaNTD - beta interaction site [polypeptide binding]; other site
1124991000955	alphaNTD - beta' interaction site [polypeptide binding]; other site
1124991000956	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1124991000957	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1124991000958	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1124991000959	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991000960	RNA binding surface [nucleotide binding]; other site
1124991000961	30S ribosomal protein S11; Validated; Region: PRK05309
1124991000962	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1124991000963	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1124991000964	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1124991000965	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1124991000966	SecY translocase; Region: SecY; pfam00344
1124991000967	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1124991000968	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1124991000969	23S rRNA binding site [nucleotide binding]; other site
1124991000970	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1124991000971	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1124991000972	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1124991000973	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1124991000974	5S rRNA interface [nucleotide binding]; other site
1124991000975	23S rRNA interface [nucleotide binding]; other site
1124991000976	L5 interface [polypeptide binding]; other site
1124991000977	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1124991000978	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1124991000979	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1124991000980	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1124991000981	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1124991000982	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1124991000983	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1124991000984	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1124991000985	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1124991000986	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1124991000987	RNA binding site [nucleotide binding]; other site
1124991000988	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1124991000989	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1124991000990	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1124991000991	23S rRNA interface [nucleotide binding]; other site
1124991000992	putative translocon interaction site; other site
1124991000993	signal recognition particle (SRP54) interaction site; other site
1124991000994	L23 interface [polypeptide binding]; other site
1124991000995	trigger factor interaction site; other site
1124991000996	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1124991000997	23S rRNA interface [nucleotide binding]; other site
1124991000998	5S rRNA interface [nucleotide binding]; other site
1124991000999	putative antibiotic binding site [chemical binding]; other site
1124991001000	L25 interface [polypeptide binding]; other site
1124991001001	L27 interface [polypeptide binding]; other site
1124991001002	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1124991001003	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1124991001004	G-X-X-G motif; other site
1124991001005	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1124991001006	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1124991001007	protein-rRNA interface [nucleotide binding]; other site
1124991001008	putative translocon binding site; other site
1124991001009	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1124991001010	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1124991001011	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1124991001012	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1124991001013	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1124991001014	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1124991001015	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1124991001016	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1124991001017	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1124991001018	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1124991001019	heme binding site [chemical binding]; other site
1124991001020	ferroxidase pore; other site
1124991001021	ferroxidase diiron center [ion binding]; other site
1124991001022	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; cl01093
1124991001023	elongation factor Tu; Reviewed; Region: PRK00049
1124991001024	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1124991001025	G1 box; other site
1124991001026	GEF interaction site [polypeptide binding]; other site
1124991001027	GTP/Mg2+ binding site [chemical binding]; other site
1124991001028	Switch I region; other site
1124991001029	G2 box; other site
1124991001030	G3 box; other site
1124991001031	Switch II region; other site
1124991001032	G4 box; other site
1124991001033	G5 box; other site
1124991001034	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1124991001035	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1124991001036	Antibiotic Binding Site [chemical binding]; other site
1124991001037	pantothenate kinase; Provisional; Region: PRK05439
1124991001038	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1124991001039	ATP-binding site [chemical binding]; other site
1124991001040	CoA-binding site [chemical binding]; other site
1124991001041	Mg2+-binding site [ion binding]; other site
1124991001042	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1124991001043	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1124991001044	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1124991001045	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1124991001046	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1124991001047	FAD binding domain; Region: FAD_binding_4; pfam01565
1124991001048	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1124991001049	glutamate racemase; Provisional; Region: PRK00865
1124991001050	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1124991001051	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991001052	N-terminal plug; other site
1124991001053	ligand-binding site [chemical binding]; other site
1124991001054	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1124991001055	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991001056	S-adenosylmethionine binding site [chemical binding]; other site
1124991001057	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
1124991001058	Pollen proteins Ole e I like; Region: Pollen_Ole_e_I; pfam01190
1124991001059	cobalt transport protein CbiM; Validated; Region: PRK06265
1124991001060	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1124991001061	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1124991001062	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
1124991001063	Walker A/P-loop; other site
1124991001064	ATP binding site [chemical binding]; other site
1124991001065	Q-loop/lid; other site
1124991001066	ABC transporter signature motif; other site
1124991001067	Walker B; other site
1124991001068	D-loop; other site
1124991001069	H-loop/switch region; other site
1124991001070	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1124991001071	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1124991001072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991001073	dimer interface [polypeptide binding]; other site
1124991001074	conserved gate region; other site
1124991001075	putative PBP binding loops; other site
1124991001076	ABC-ATPase subunit interface; other site
1124991001077	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991001078	dimer interface [polypeptide binding]; other site
1124991001079	conserved gate region; other site
1124991001080	putative PBP binding loops; other site
1124991001081	ABC-ATPase subunit interface; other site
1124991001082	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1124991001083	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991001084	substrate binding pocket [chemical binding]; other site
1124991001085	membrane-bound complex binding site; other site
1124991001086	hinge residues; other site
1124991001087	Fimbrial protein; Region: Fimbrial; cl01416
1124991001088	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1124991001089	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991001090	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991001091	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991001092	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1124991001093	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991001094	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991001095	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991001096	Fimbrial protein; Region: Fimbrial; pfam00419
1124991001097	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1124991001098	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991001099	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991001100	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
1124991001101	transcriptional regulator PhoU; Provisional; Region: PRK11115
1124991001102	PhoU domain; Region: PhoU; pfam01895
1124991001103	PhoU domain; Region: PhoU; pfam01895
1124991001104	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1124991001105	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1124991001106	Walker A/P-loop; other site
1124991001107	ATP binding site [chemical binding]; other site
1124991001108	Q-loop/lid; other site
1124991001109	ABC transporter signature motif; other site
1124991001110	Walker B; other site
1124991001111	D-loop; other site
1124991001112	H-loop/switch region; other site
1124991001113	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1124991001114	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991001115	dimer interface [polypeptide binding]; other site
1124991001116	conserved gate region; other site
1124991001117	putative PBP binding loops; other site
1124991001118	ABC-ATPase subunit interface; other site
1124991001119	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1124991001120	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991001121	dimer interface [polypeptide binding]; other site
1124991001122	conserved gate region; other site
1124991001123	putative PBP binding loops; other site
1124991001124	ABC-ATPase subunit interface; other site
1124991001125	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991001126	substrate binding pocket [chemical binding]; other site
1124991001127	membrane-bound complex binding site; other site
1124991001128	hinge residues; other site
1124991001129	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1124991001130	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991001131	dimerization interface [polypeptide binding]; other site
1124991001132	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991001133	dimer interface [polypeptide binding]; other site
1124991001134	phosphorylation site [posttranslational modification]
1124991001135	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991001136	ATP binding site [chemical binding]; other site
1124991001137	Mg2+ binding site [ion binding]; other site
1124991001138	G-X-G motif; other site
1124991001139	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1124991001140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991001141	active site
1124991001142	phosphorylation site [posttranslational modification]
1124991001143	intermolecular recognition site; other site
1124991001144	dimerization interface [polypeptide binding]; other site
1124991001145	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991001146	DNA binding site [nucleotide binding]
1124991001147	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1124991001148	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1124991001149	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1124991001150	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1124991001151	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1124991001152	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1124991001153	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1124991001154	RNA binding site [nucleotide binding]; other site
1124991001155	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1124991001156	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1124991001157	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1124991001158	G1 box; other site
1124991001159	GTP/Mg2+ binding site [chemical binding]; other site
1124991001160	Switch I region; other site
1124991001161	G2 box; other site
1124991001162	G3 box; other site
1124991001163	Switch II region; other site
1124991001164	G4 box; other site
1124991001165	G5 box; other site
1124991001166	Nucleoside recognition; Region: Gate; pfam07670
1124991001167	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1124991001168	Nucleoside recognition; Region: Gate; pfam07670
1124991001169	FeoC like transcriptional regulator; Region: FeoC; cl17677
1124991001170	carboxylesterase BioH; Provisional; Region: PRK10349
1124991001171	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1124991001172	DNA utilization protein GntX; Provisional; Region: PRK11595
1124991001173	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991001174	active site
1124991001175	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1124991001176	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1124991001177	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1124991001178	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1124991001179	active site residue [active]
1124991001180	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1124991001181	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1124991001182	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1124991001183	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1124991001184	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1124991001185	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1124991001186	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1124991001187	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1124991001188	Protein of unknown function (DUF4026); Region: DUF4026; pfam13218
1124991001189	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
1124991001190	AlkA N-terminal domain; Region: AlkA_N; cl05528
1124991001191	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1124991001192	endonuclease III; Region: ENDO3c; smart00478
1124991001193	minor groove reading motif; other site
1124991001194	helix-hairpin-helix signature motif; other site
1124991001195	substrate binding pocket [chemical binding]; other site
1124991001196	active site
1124991001197	pyruvate dehydrogenase; Provisional; Region: PRK09124
1124991001198	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1124991001199	PYR/PP interface [polypeptide binding]; other site
1124991001200	dimer interface [polypeptide binding]; other site
1124991001201	tetramer interface [polypeptide binding]; other site
1124991001202	TPP binding site [chemical binding]; other site
1124991001203	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991001204	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1124991001205	TPP-binding site [chemical binding]; other site
1124991001206	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1124991001207	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1124991001208	metal binding site [ion binding]; metal-binding site
1124991001209	dimer interface [polypeptide binding]; other site
1124991001210	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1124991001211	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991001212	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1124991001213	substrate binding site [chemical binding]; other site
1124991001214	dimerization interface [polypeptide binding]; other site
1124991001215	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991001216	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991001217	non-specific DNA binding site [nucleotide binding]; other site
1124991001218	salt bridge; other site
1124991001219	sequence-specific DNA binding site [nucleotide binding]; other site
1124991001220	proline/glycine betaine transporter; Provisional; Region: PRK10642
1124991001221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001222	putative substrate translocation pore; other site
1124991001223	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1124991001224	DNA photolyase; Region: DNA_photolyase; pfam00875
1124991001225	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1124991001226	Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism]; Region: TyrR; COG3283
1124991001227	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991001228	Walker A motif; other site
1124991001229	ATP binding site [chemical binding]; other site
1124991001230	Walker B motif; other site
1124991001231	arginine finger; other site
1124991001232	methionine gamma-lyase; Provisional; Region: PRK06234
1124991001233	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991001234	homodimer interface [polypeptide binding]; other site
1124991001235	substrate-cofactor binding pocket; other site
1124991001236	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991001237	catalytic residue [active]
1124991001238	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991001239	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1124991001240	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991001241	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991001242	non-specific DNA binding site [nucleotide binding]; other site
1124991001243	salt bridge; other site
1124991001244	sequence-specific DNA binding site [nucleotide binding]; other site
1124991001245	putative acyltransferase; Provisional; Region: PRK05790
1124991001246	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1124991001247	dimer interface [polypeptide binding]; other site
1124991001248	active site
1124991001249	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
1124991001250	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1124991001251	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
1124991001252	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
1124991001253	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991001254	active site
1124991001255	phosphorylation site [posttranslational modification]
1124991001256	intermolecular recognition site; other site
1124991001257	dimerization interface [polypeptide binding]; other site
1124991001258	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991001259	Walker A motif; other site
1124991001260	ATP binding site [chemical binding]; other site
1124991001261	Walker B motif; other site
1124991001262	arginine finger; other site
1124991001263	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1124991001264	sensory histidine kinase AtoS; Provisional; Region: PRK11360
1124991001265	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1124991001266	putative active site [active]
1124991001267	heme pocket [chemical binding]; other site
1124991001268	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991001269	dimer interface [polypeptide binding]; other site
1124991001270	phosphorylation site [posttranslational modification]
1124991001271	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991001272	ATP binding site [chemical binding]; other site
1124991001273	Mg2+ binding site [ion binding]; other site
1124991001274	G-X-G motif; other site
1124991001275	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1124991001276	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1124991001277	active site
1124991001278	intersubunit interface [polypeptide binding]; other site
1124991001279	catalytic residue [active]
1124991001280	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1124991001281	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1124991001282	substrate binding site [chemical binding]; other site
1124991001283	ATP binding site [chemical binding]; other site
1124991001284	Glucuronate isomerase; Region: UxaC; pfam02614
1124991001285	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1124991001286	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1124991001287	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1124991001288	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1124991001289	mannonate dehydratase; Provisional; Region: PRK03906
1124991001290	mannonate dehydratase; Region: uxuA; TIGR00695
1124991001291	DctM-like transporters; Region: DctM; pfam06808
1124991001292	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1124991001293	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1124991001294	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1124991001295	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991001296	membrane-bound complex binding site; other site
1124991001297	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1124991001298	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991001299	DNA-binding site [nucleotide binding]; DNA binding site
1124991001300	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1124991001301	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1124991001302	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991001303	homodimer interface [polypeptide binding]; other site
1124991001304	substrate-cofactor binding pocket; other site
1124991001305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991001306	catalytic residue [active]
1124991001307	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1124991001308	D-cysteine desulfhydrase; Validated; Region: PRK03910
1124991001309	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1124991001310	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991001311	catalytic residue [active]
1124991001312	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991001313	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1124991001314	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991001315	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991001316	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1124991001317	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991001318	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991001319	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991001320	Fimbrial protein; Region: Fimbrial; pfam00419
1124991001321	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1124991001322	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1124991001323	Na binding site [ion binding]; other site
1124991001324	Predicted membrane protein [Function unknown]; Region: COG3162
1124991001325	acetyl-CoA synthetase; Provisional; Region: PRK00174
1124991001326	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1124991001327	active site
1124991001328	CoA binding site [chemical binding]; other site
1124991001329	acyl-activating enzyme (AAE) consensus motif; other site
1124991001330	AMP binding site [chemical binding]; other site
1124991001331	acetate binding site [chemical binding]; other site
1124991001332	superoxide dismutase; Provisional; Region: PRK10925
1124991001333	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1124991001334	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1124991001335	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1124991001336	MOSC domain; Region: MOSC; pfam03473
1124991001337	3-alpha domain; Region: 3-alpha; pfam03475
1124991001338	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1124991001339	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1124991001340	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1124991001341	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991001342	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1124991001343	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1124991001344	putative [Fe4-S4] binding site [ion binding]; other site
1124991001345	putative molybdopterin cofactor binding site [chemical binding]; other site
1124991001346	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1124991001347	putative molybdopterin cofactor binding site; other site
1124991001348	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991001349	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1124991001350	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1124991001351	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1124991001352	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1124991001353	active site
1124991001354	HIGH motif; other site
1124991001355	dimer interface [polypeptide binding]; other site
1124991001356	KMSKS motif; other site
1124991001357	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1124991001358	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991001359	motif II; other site
1124991001360	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1124991001361	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1124991001362	substrate binding site [chemical binding]; other site
1124991001363	hexamer interface [polypeptide binding]; other site
1124991001364	metal binding site [ion binding]; metal-binding site
1124991001365	DNA adenine methylase; Provisional; Region: PRK10904
1124991001366	cell division protein DamX; Validated; Region: PRK10905
1124991001367	cell division protein DamX; Validated; Region: PRK10905
1124991001368	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1124991001369	active site
1124991001370	dimer interface [polypeptide binding]; other site
1124991001371	metal binding site [ion binding]; metal-binding site
1124991001372	shikimate kinase; Reviewed; Region: aroK; PRK00131
1124991001373	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1124991001374	ADP binding site [chemical binding]; other site
1124991001375	magnesium binding site [ion binding]; other site
1124991001376	putative shikimate binding site; other site
1124991001377	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1124991001378	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
1124991001379	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1124991001380	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1124991001381	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1124991001382	Sodium/glutamate symporter; Region: Glt_symporter; pfam03616
1124991001383	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1124991001384	homoserine dehydrogenase; Provisional; Region: PRK06349
1124991001385	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991001386	dimerization interface [polypeptide binding]; other site
1124991001387	putative DNA binding site [nucleotide binding]; other site
1124991001388	putative Zn2+ binding site [ion binding]; other site
1124991001389	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1124991001390	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991001391	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1124991001392	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001393	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1124991001394	putative substrate translocation pore; other site
1124991001395	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991001396	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991001397	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1124991001398	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991001399	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991001400	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1124991001401	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1124991001402	Transglycosylase; Region: Transgly; pfam00912
1124991001403	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1124991001404	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1124991001405	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1124991001406	ADP-ribose binding site [chemical binding]; other site
1124991001407	dimer interface [polypeptide binding]; other site
1124991001408	active site
1124991001409	nudix motif; other site
1124991001410	metal binding site [ion binding]; metal-binding site
1124991001411	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1124991001412	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991001413	RNA binding surface [nucleotide binding]; other site
1124991001414	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1124991001415	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1124991001416	dimerization interface [polypeptide binding]; other site
1124991001417	domain crossover interface; other site
1124991001418	redox-dependent activation switch; other site
1124991001419	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1124991001420	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1124991001421	active site
1124991001422	substrate-binding site [chemical binding]; other site
1124991001423	metal-binding site [ion binding]
1124991001424	ATP binding site [chemical binding]; other site
1124991001425	Pirin-related protein [General function prediction only]; Region: COG1741
1124991001426	Pirin; Region: Pirin; pfam02678
1124991001427	Predicted flavoproteins [General function prediction only]; Region: COG2081
1124991001428	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991001429	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1124991001430	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1124991001431	universal stress protein UspB; Provisional; Region: PRK04960
1124991001432	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991001433	Ligand Binding Site [chemical binding]; other site
1124991001434	glutamate dehydrogenase; Provisional; Region: PRK09414
1124991001435	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1124991001436	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1124991001437	NAD(P) binding site [chemical binding]; other site
1124991001438	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991001439	S-adenosylmethionine binding site [chemical binding]; other site
1124991001440	oligopeptidase A; Provisional; Region: PRK10911
1124991001441	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1124991001442	active site
1124991001443	Zn binding site [ion binding]; other site
1124991001444	Virulence protein [General function prediction only]; Region: COG3943
1124991001445	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1124991001446	hypothetical protein; Provisional; Region: PRK11020
1124991001447	Protein of unknown function DUF91; Region: DUF91; cl00709
1124991001448	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1124991001449	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1124991001450	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1124991001451	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1124991001452	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1124991001453	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1124991001454	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1124991001455	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1124991001456	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1124991001457	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991001458	ATP binding site [chemical binding]; other site
1124991001459	putative Mg++ binding site [ion binding]; other site
1124991001460	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1124991001461	Protein of unknown function (DUF1007); Region: DUF1007; pfam06226
1124991001462	Cache domain; Region: Cache_1; pfam02743
1124991001463	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991001464	dimerization interface [polypeptide binding]; other site
1124991001465	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1124991001466	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991001467	dimer interface [polypeptide binding]; other site
1124991001468	putative CheW interface [polypeptide binding]; other site
1124991001469	putative S-transferase; Provisional; Region: PRK11752
1124991001470	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1124991001471	C-terminal domain interface [polypeptide binding]; other site
1124991001472	GSH binding site (G-site) [chemical binding]; other site
1124991001473	dimer interface [polypeptide binding]; other site
1124991001474	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1124991001475	dimer interface [polypeptide binding]; other site
1124991001476	N-terminal domain interface [polypeptide binding]; other site
1124991001477	active site
1124991001478	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1124991001479	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991001480	DNA-binding site [nucleotide binding]; DNA binding site
1124991001481	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1124991001482	putative transporter; Provisional; Region: PRK10504
1124991001483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001485	transcriptional repressor RbsR; Provisional; Region: PRK10423
1124991001486	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991001487	DNA binding site [nucleotide binding]
1124991001488	domain linker motif; other site
1124991001489	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1124991001490	dimerization interface [polypeptide binding]; other site
1124991001491	ligand binding site [chemical binding]; other site
1124991001492	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1124991001493	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1124991001494	substrate binding site [chemical binding]; other site
1124991001495	dimer interface [polypeptide binding]; other site
1124991001496	ATP binding site [chemical binding]; other site
1124991001497	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1124991001498	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1124991001499	ligand binding site [chemical binding]; other site
1124991001500	dimerization interface [polypeptide binding]; other site
1124991001501	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991001502	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991001503	TM-ABC transporter signature motif; other site
1124991001504	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1124991001505	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1124991001506	Walker A/P-loop; other site
1124991001507	ATP binding site [chemical binding]; other site
1124991001508	Q-loop/lid; other site
1124991001509	ABC transporter signature motif; other site
1124991001510	Walker B; other site
1124991001511	D-loop; other site
1124991001512	H-loop/switch region; other site
1124991001513	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1124991001514	D-ribose pyranase; Provisional; Region: PRK11797
1124991001515	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1124991001516	regulatory ATPase RavA; Provisional; Region: PRK13531
1124991001517	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991001518	Walker A motif; other site
1124991001519	ATP binding site [chemical binding]; other site
1124991001520	Walker B motif; other site
1124991001521	arginine finger; other site
1124991001522	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1124991001523	hypothetical protein; Provisional; Region: yieM; PRK10997
1124991001524	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1124991001525	metal ion-dependent adhesion site (MIDAS); other site
1124991001526	Asparagine synthetase A [Amino acid transport and metabolism]; Region: AsnA; COG2502
1124991001527	motif 1; other site
1124991001528	dimer interface [polypeptide binding]; other site
1124991001529	active site
1124991001530	motif 2; other site
1124991001531	motif 3; other site
1124991001532	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1124991001533	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991001534	dimerization interface [polypeptide binding]; other site
1124991001535	putative DNA binding site [nucleotide binding]; other site
1124991001536	putative Zn2+ binding site [ion binding]; other site
1124991001537	AsnC family; Region: AsnC_trans_reg; pfam01037
1124991001538	FMN-binding protein MioC; Provisional; Region: PRK09004
1124991001539	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1124991001540	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1124991001541	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1124991001542	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1124991001543	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1124991001544	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1124991001545	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1124991001546	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1124991001547	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1124991001548	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1124991001549	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1124991001550	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1124991001551	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1124991001552	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1124991001553	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1124991001554	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1124991001555	Walker A motif; other site
1124991001556	ATP binding site [chemical binding]; other site
1124991001557	Walker B motif; other site
1124991001558	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1124991001559	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1124991001560	core domain interface [polypeptide binding]; other site
1124991001561	delta subunit interface [polypeptide binding]; other site
1124991001562	epsilon subunit interface [polypeptide binding]; other site
1124991001563	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1124991001564	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1124991001565	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1124991001566	alpha subunit interaction interface [polypeptide binding]; other site
1124991001567	Walker A motif; other site
1124991001568	ATP binding site [chemical binding]; other site
1124991001569	Walker B motif; other site
1124991001570	inhibitor binding site; inhibition site
1124991001571	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1124991001572	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1124991001573	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1124991001574	gamma subunit interface [polypeptide binding]; other site
1124991001575	epsilon subunit interface [polypeptide binding]; other site
1124991001576	LBP interface [polypeptide binding]; other site
1124991001577	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1124991001578	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1124991001579	Substrate binding site; other site
1124991001580	Mg++ binding site; other site
1124991001581	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1124991001582	active site
1124991001583	substrate binding site [chemical binding]; other site
1124991001584	CoA binding site [chemical binding]; other site
1124991001585	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1124991001586	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1124991001587	glutaminase active site [active]
1124991001588	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1124991001589	dimer interface [polypeptide binding]; other site
1124991001590	active site
1124991001591	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1124991001592	dimer interface [polypeptide binding]; other site
1124991001593	active site
1124991001594	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1124991001595	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1124991001596	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991001597	dimer interface [polypeptide binding]; other site
1124991001598	putative CheW interface [polypeptide binding]; other site
1124991001599	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1124991001600	PAS domain; Region: PAS_9; pfam13426
1124991001601	putative active site [active]
1124991001602	heme pocket [chemical binding]; other site
1124991001603	HAMP domain; Region: HAMP; pfam00672
1124991001604	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1124991001605	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991001606	dimer interface [polypeptide binding]; other site
1124991001607	putative CheW interface [polypeptide binding]; other site
1124991001608	Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; cl02212
1124991001609	fructokinase; Reviewed; Region: PRK09557
1124991001610	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1124991001611	nucleotide binding site [chemical binding]; other site
1124991001612	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1124991001613	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1124991001614	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1124991001615	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991001616	catalytic residue [active]
1124991001617	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1124991001618	glutaminase; Reviewed; Region: PRK12356
1124991001619	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1124991001620	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1124991001621	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1124991001622	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1124991001623	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1124991001624	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991001625	Mg2+ binding site [ion binding]; other site
1124991001626	G-X-G motif; other site
1124991001627	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1124991001628	anchoring element; other site
1124991001629	dimer interface [polypeptide binding]; other site
1124991001630	ATP binding site [chemical binding]; other site
1124991001631	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1124991001632	active site
1124991001633	putative metal-binding site [ion binding]; other site
1124991001634	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1124991001635	recF protein; Region: recf; TIGR00611
1124991001636	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991001637	Walker A/P-loop; other site
1124991001638	ATP binding site [chemical binding]; other site
1124991001639	Q-loop/lid; other site
1124991001640	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991001641	ABC transporter signature motif; other site
1124991001642	Walker B; other site
1124991001643	D-loop; other site
1124991001644	H-loop/switch region; other site
1124991001645	DNA polymerase III subunit beta; Validated; Region: PRK05643
1124991001646	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1124991001647	putative DNA binding surface [nucleotide binding]; other site
1124991001648	dimer interface [polypeptide binding]; other site
1124991001649	beta-clamp/clamp loader binding surface; other site
1124991001650	beta-clamp/translesion DNA polymerase binding surface; other site
1124991001651	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1124991001652	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1124991001653	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991001654	Walker A motif; other site
1124991001655	ATP binding site [chemical binding]; other site
1124991001656	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1124991001657	Walker B motif; other site
1124991001658	arginine finger; other site
1124991001659	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1124991001660	DnaA box-binding interface [nucleotide binding]; other site
1124991001661	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1124991001662	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1124991001663	hypothetical protein; Validated; Region: PRK00041
1124991001664	membrane protein insertase; Provisional; Region: PRK01318
1124991001665	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1124991001666	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1124991001667	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1124991001668	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1124991001669	G1 box; other site
1124991001670	GTP/Mg2+ binding site [chemical binding]; other site
1124991001671	Switch I region; other site
1124991001672	G2 box; other site
1124991001673	Switch II region; other site
1124991001674	G3 box; other site
1124991001675	G4 box; other site
1124991001676	G5 box; other site
1124991001677	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1124991001678	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1124991001679	EamA-like transporter family; Region: EamA; pfam00892
1124991001680	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991001681	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991001682	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1124991001683	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1124991001684	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1124991001685	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1124991001686	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1124991001687	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1124991001688	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1124991001689	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1124991001690	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1124991001691	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991001692	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991001693	molybdopterin cofactor binding site; other site
1124991001694	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1124991001695	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1124991001696	molybdopterin cofactor binding site; other site
1124991001697	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1124991001698	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1124991001699	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1124991001700	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1124991001701	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1124991001702	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1124991001703	selenocysteine synthase; Provisional; Region: PRK04311
1124991001704	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1124991001705	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1124991001706	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991001707	catalytic residue [active]
1124991001708	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1124991001709	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1124991001710	G1 box; other site
1124991001711	putative GEF interaction site [polypeptide binding]; other site
1124991001712	GTP/Mg2+ binding site [chemical binding]; other site
1124991001713	Switch I region; other site
1124991001714	G2 box; other site
1124991001715	G3 box; other site
1124991001716	Switch II region; other site
1124991001717	G4 box; other site
1124991001718	G5 box; other site
1124991001719	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1124991001720	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1124991001721	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1124991001722	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1124991001723	Domain of unknown function (DUF1792); Region: DUF1792; cl07392
1124991001724	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1124991001725	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1124991001726	Predicted transcriptional regulator [Transcription]; Region: COG2345
1124991001727	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001728	putative substrate translocation pore; other site
1124991001729	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1124991001730	Protein of unknown function, DUF; Region: DUF411; cl01142
1124991001731	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1124991001732	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1124991001733	gating phenylalanine in ion channel; other site
1124991001734	xanthine permease; Region: pbuX; TIGR03173
1124991001735	hypothetical protein; Provisional; Region: PRK11820
1124991001736	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1124991001737	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1124991001738	ribonuclease PH; Reviewed; Region: rph; PRK00173
1124991001739	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1124991001740	hexamer interface [polypeptide binding]; other site
1124991001741	active site
1124991001742	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991001743	active site
1124991001744	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1124991001745	division inhibitor protein; Provisional; Region: slmA; PRK09480
1124991001746	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991001747	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1124991001748	trimer interface [polypeptide binding]; other site
1124991001749	active site
1124991001750	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1124991001751	Flavoprotein; Region: Flavoprotein; pfam02441
1124991001752	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1124991001753	hypothetical protein; Reviewed; Region: PRK00024
1124991001754	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1124991001755	MPN+ (JAMM) motif; other site
1124991001756	Zinc-binding site [ion binding]; other site
1124991001757	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1124991001758	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1124991001759	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1124991001760	active site
1124991001761	O-Antigen ligase; Region: Wzy_C; pfam04932
1124991001762	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1124991001763	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1124991001764	DNA binding site [nucleotide binding]
1124991001765	catalytic residue [active]
1124991001766	H2TH interface [polypeptide binding]; other site
1124991001767	putative catalytic residues [active]
1124991001768	turnover-facilitating residue; other site
1124991001769	intercalation triad [nucleotide binding]; other site
1124991001770	8OG recognition residue [nucleotide binding]; other site
1124991001771	putative reading head residues; other site
1124991001772	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1124991001773	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1124991001774	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1124991001775	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1124991001776	active site
1124991001777	(T/H)XGH motif; other site
1124991001778	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1124991001779	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1124991001780	putative metal binding site; other site
1124991001781	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1124991001782	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1124991001783	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1124991001784	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1124991001785	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1124991001786	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1124991001787	putative active site [active]
1124991001788	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1124991001789	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1124991001790	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1124991001791	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1124991001792	putative ADP-binding pocket [chemical binding]; other site
1124991001793	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
1124991001794	putative active site [active]
1124991001795	putative catalytic site [active]
1124991001796	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1124991001797	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1124991001798	putative active site [active]
1124991001799	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1124991001800	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1124991001801	putative active site [active]
1124991001802	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1124991001803	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1124991001804	NADP binding site [chemical binding]; other site
1124991001805	homopentamer interface [polypeptide binding]; other site
1124991001806	substrate binding site [chemical binding]; other site
1124991001807	active site
1124991001808	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1124991001809	NodB motif; other site
1124991001810	putative active site [active]
1124991001811	putative catalytic site [active]
1124991001812	Zn binding site [ion binding]; other site
1124991001813	AmiB activator; Provisional; Region: PRK11637
1124991001814	Peptidase family M23; Region: Peptidase_M23; pfam01551
1124991001815	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1124991001816	active site residue [active]
1124991001817	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1124991001818	SecA binding site; other site
1124991001819	Preprotein binding site; other site
1124991001820	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1124991001821	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1124991001822	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1124991001823	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1124991001824	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1124991001825	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1124991001826	trimer interface [polypeptide binding]; other site
1124991001827	active site
1124991001828	substrate binding site [chemical binding]; other site
1124991001829	CoA binding site [chemical binding]; other site
1124991001830	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1124991001831	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1124991001832	trimer interface [polypeptide binding]; other site
1124991001833	active site
1124991001834	CoA binding site [chemical binding]; other site
1124991001835	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
1124991001836	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1124991001837	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1124991001838	active site
1124991001839	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1124991001840	NeuB family; Region: NeuB; pfam03102
1124991001841	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1124991001842	NeuB binding interface [polypeptide binding]; other site
1124991001843	putative substrate binding site [chemical binding]; other site
1124991001844	WbqC-like protein family; Region: WbqC; pfam08889
1124991001845	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1124991001846	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991001847	dimerization interface [polypeptide binding]; other site
1124991001848	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991001849	dimer interface [polypeptide binding]; other site
1124991001850	phosphorylation site [posttranslational modification]
1124991001851	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991001852	ATP binding site [chemical binding]; other site
1124991001853	Mg2+ binding site [ion binding]; other site
1124991001854	G-X-G motif; other site
1124991001855	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1124991001856	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991001857	active site
1124991001858	intermolecular recognition site; other site
1124991001859	dimerization interface [polypeptide binding]; other site
1124991001860	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991001861	DNA binding site [nucleotide binding]
1124991001862	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1124991001863	dimer interface [polypeptide binding]; other site
1124991001864	hypothetical protein; Provisional; Region: PRK09945
1124991001865	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1124991001866	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991001867	Autotransporter beta-domain; Region: Autotransporter; smart00869
1124991001868	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1124991001869	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1124991001870	active site
1124991001871	ADP/pyrophosphate binding site [chemical binding]; other site
1124991001872	dimerization interface [polypeptide binding]; other site
1124991001873	allosteric effector site; other site
1124991001874	fructose-1,6-bisphosphate binding site; other site
1124991001875	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1124991001876	triosephosphate isomerase; Provisional; Region: PRK14567
1124991001877	substrate binding site [chemical binding]; other site
1124991001878	dimer interface [polypeptide binding]; other site
1124991001879	catalytic triad [active]
1124991001880	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1124991001881	Predicted membrane protein [Function unknown]; Region: COG3152
1124991001882	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1124991001883	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1124991001884	FAD binding pocket [chemical binding]; other site
1124991001885	FAD binding motif [chemical binding]; other site
1124991001886	phosphate binding motif [ion binding]; other site
1124991001887	beta-alpha-beta structure motif; other site
1124991001888	NAD binding pocket [chemical binding]; other site
1124991001889	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1124991001890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001891	putative substrate translocation pore; other site
1124991001892	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1124991001893	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1124991001894	active site
1124991001895	catalytic site [active]
1124991001896	metal binding site [ion binding]; metal-binding site
1124991001897	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1124991001898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991001899	putative substrate translocation pore; other site
1124991001900	glycerol kinase; Provisional; Region: glpK; PRK00047
1124991001901	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1124991001902	N- and C-terminal domain interface [polypeptide binding]; other site
1124991001903	active site
1124991001904	MgATP binding site [chemical binding]; other site
1124991001905	catalytic site [active]
1124991001906	metal binding site [ion binding]; metal-binding site
1124991001907	glycerol binding site [chemical binding]; other site
1124991001908	homotetramer interface [polypeptide binding]; other site
1124991001909	homodimer interface [polypeptide binding]; other site
1124991001910	FBP binding site [chemical binding]; other site
1124991001911	protein IIAGlc interface [polypeptide binding]; other site
1124991001912	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1124991001913	amphipathic channel; other site
1124991001914	Asn-Pro-Ala signature motifs; other site
1124991001915	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
1124991001916	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1124991001917	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1124991001918	UbiA prenyltransferase family; Region: UbiA; pfam01040
1124991001919	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1124991001920	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991001921	Walker A motif; other site
1124991001922	ATP binding site [chemical binding]; other site
1124991001923	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1124991001924	Walker B motif; other site
1124991001925	arginine finger; other site
1124991001926	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1124991001927	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1124991001928	active site
1124991001929	HslU subunit interaction site [polypeptide binding]; other site
1124991001930	cell division protein FtsN; Provisional; Region: PRK12757
1124991001931	Sporulation related domain; Region: SPOR; cl10051
1124991001932	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991001933	DNA binding site [nucleotide binding]
1124991001934	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1124991001935	domain linker motif; other site
1124991001936	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1124991001937	dimerization interface [polypeptide binding]; other site
1124991001938	ligand binding site [chemical binding]; other site
1124991001939	primosome assembly protein PriA; Validated; Region: PRK05580
1124991001940	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991001941	ATP binding site [chemical binding]; other site
1124991001942	putative Mg++ binding site [ion binding]; other site
1124991001943	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1124991001944	ATP-binding site [chemical binding]; other site
1124991001945	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1124991001946	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1124991001947	dimerization interface [polypeptide binding]; other site
1124991001948	DNA binding site [nucleotide binding]
1124991001949	corepressor binding sites; other site
1124991001950	cystathionine gamma-synthase; Provisional; Region: PRK08045
1124991001951	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991001952	homodimer interface [polypeptide binding]; other site
1124991001953	substrate-cofactor binding pocket; other site
1124991001954	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991001955	catalytic residue [active]
1124991001956	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1124991001957	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1124991001958	putative catalytic residues [active]
1124991001959	putative nucleotide binding site [chemical binding]; other site
1124991001960	putative aspartate binding site [chemical binding]; other site
1124991001961	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1124991001962	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1124991001963	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1124991001964	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1124991001965	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
1124991001966	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1124991001967	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1124991001968	FAD binding site [chemical binding]; other site
1124991001969	acetylornithine deacetylase; Provisional; Region: PRK05111
1124991001970	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1124991001971	metal binding site [ion binding]; metal-binding site
1124991001972	putative dimer interface [polypeptide binding]; other site
1124991001973	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1124991001974	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1124991001975	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1124991001976	nucleotide binding site [chemical binding]; other site
1124991001977	substrate binding site [chemical binding]; other site
1124991001978	argininosuccinate synthase; Provisional; Region: PRK13820
1124991001979	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1124991001980	ANP binding site [chemical binding]; other site
1124991001981	Substrate Binding Site II [chemical binding]; other site
1124991001982	Substrate Binding Site I [chemical binding]; other site
1124991001983	argininosuccinate lyase; Provisional; Region: PRK04833
1124991001984	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1124991001985	active sites [active]
1124991001986	tetramer interface [polypeptide binding]; other site
1124991001987	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1124991001988	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991001989	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1124991001990	dimerization interface [polypeptide binding]; other site
1124991001991	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1124991001992	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991001993	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991001994	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1124991001995	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1124991001996	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991001997	hypothetical protein; Provisional; Region: PRK11056
1124991001998	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1124991001999	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1124991002000	Der GTPase activator; Provisional; Region: PRK05244
1124991002001	Sugar efflux transporter for intercellular exchange; Region: MtN3_slv; pfam03083
1124991002002	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1124991002003	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991002004	FeS/SAM binding site; other site
1124991002005	HemN C-terminal domain; Region: HemN_C; pfam06969
1124991002006	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1124991002007	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991002008	active site
1124991002009	phosphorylation site [posttranslational modification]
1124991002010	intermolecular recognition site; other site
1124991002011	dimerization interface [polypeptide binding]; other site
1124991002012	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991002013	Walker A motif; other site
1124991002014	ATP binding site [chemical binding]; other site
1124991002015	Walker B motif; other site
1124991002016	arginine finger; other site
1124991002017	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1124991002018	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1124991002019	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1124991002020	putative active site [active]
1124991002021	heme pocket [chemical binding]; other site
1124991002022	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991002023	dimer interface [polypeptide binding]; other site
1124991002024	phosphorylation site [posttranslational modification]
1124991002025	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991002026	ATP binding site [chemical binding]; other site
1124991002027	Mg2+ binding site [ion binding]; other site
1124991002028	G-X-G motif; other site
1124991002029	glutamine synthetase; Provisional; Region: glnA; PRK09469
1124991002030	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1124991002031	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1124991002032	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1124991002033	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1124991002034	G1 box; other site
1124991002035	putative GEF interaction site [polypeptide binding]; other site
1124991002036	GTP/Mg2+ binding site [chemical binding]; other site
1124991002037	Switch I region; other site
1124991002038	G2 box; other site
1124991002039	G3 box; other site
1124991002040	Switch II region; other site
1124991002041	G4 box; other site
1124991002042	G5 box; other site
1124991002043	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1124991002044	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1124991002045	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1124991002046	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991002047	motif II; other site
1124991002048	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1124991002049	putative active site [active]
1124991002050	dimerization interface [polypeptide binding]; other site
1124991002051	putative tRNAtyr binding site [nucleotide binding]; other site
1124991002052	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991002053	Coenzyme A binding pocket [chemical binding]; other site
1124991002054	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1124991002055	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1124991002056	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1124991002057	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1124991002058	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1124991002059	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1124991002060	generic binding surface II; other site
1124991002061	ssDNA binding site; other site
1124991002062	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991002063	ATP binding site [chemical binding]; other site
1124991002064	putative Mg++ binding site [ion binding]; other site
1124991002065	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991002066	nucleotide binding region [chemical binding]; other site
1124991002067	ATP-binding site [chemical binding]; other site
1124991002068	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1124991002069	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1124991002070	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1124991002071	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1124991002072	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1124991002073	Zn2+ binding site [ion binding]; other site
1124991002074	Mg2+ binding site [ion binding]; other site
1124991002075	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1124991002076	synthetase active site [active]
1124991002077	NTP binding site [chemical binding]; other site
1124991002078	metal binding site [ion binding]; metal-binding site
1124991002079	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1124991002080	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1124991002081	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
1124991002082	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1124991002083	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1124991002084	catalytic site [active]
1124991002085	G-X2-G-X-G-K; other site
1124991002086	Predicted membrane protein [Function unknown]; Region: COG2860
1124991002087	UPF0126 domain; Region: UPF0126; pfam03458
1124991002088	UPF0126 domain; Region: UPF0126; pfam03458
1124991002089	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1124991002090	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
1124991002091	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1124991002092	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1124991002093	dimer interface [polypeptide binding]; other site
1124991002094	motif 1; other site
1124991002095	active site
1124991002096	motif 2; other site
1124991002097	motif 3; other site
1124991002098	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1124991002099	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1124991002100	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1124991002101	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1124991002102	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1124991002103	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1124991002104	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1124991002105	peptide binding site [polypeptide binding]; other site
1124991002106	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1124991002107	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002108	dimer interface [polypeptide binding]; other site
1124991002109	conserved gate region; other site
1124991002110	putative PBP binding loops; other site
1124991002111	ABC-ATPase subunit interface; other site
1124991002112	dipeptide transporter; Provisional; Region: PRK10913
1124991002113	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1124991002114	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002115	dimer interface [polypeptide binding]; other site
1124991002116	conserved gate region; other site
1124991002117	putative PBP binding loops; other site
1124991002118	ABC-ATPase subunit interface; other site
1124991002119	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1124991002120	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991002121	Walker A/P-loop; other site
1124991002122	ATP binding site [chemical binding]; other site
1124991002123	Q-loop/lid; other site
1124991002124	ABC transporter signature motif; other site
1124991002125	Walker B; other site
1124991002126	D-loop; other site
1124991002127	H-loop/switch region; other site
1124991002128	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1124991002129	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1124991002130	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991002131	Walker A/P-loop; other site
1124991002132	ATP binding site [chemical binding]; other site
1124991002133	Q-loop/lid; other site
1124991002134	ABC transporter signature motif; other site
1124991002135	Walker B; other site
1124991002136	D-loop; other site
1124991002137	H-loop/switch region; other site
1124991002138	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1124991002139	Xylella fastidiosa protein of unknown function (DUF769); Region: DUF769; pfam05590
1124991002140	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1124991002141	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991002142	Beta-lactamase; Region: Beta-lactamase; pfam00144
1124991002143	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1124991002144	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1124991002145	active site 1 [active]
1124991002146	dimer interface [polypeptide binding]; other site
1124991002147	hexamer interface [polypeptide binding]; other site
1124991002148	active site 2 [active]
1124991002149	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
1124991002150	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1124991002151	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1124991002152	glutathione reductase; Validated; Region: PRK06116
1124991002153	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991002154	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991002155	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1124991002156	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1124991002157	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991002158	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1124991002159	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
1124991002160	active site
1124991002161	metal binding site [ion binding]; metal-binding site
1124991002162	nudix motif; other site
1124991002163	HdeA/HdeB family; Region: HdeA; cl05752
1124991002164	putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB; Provisional; Region: PRK14489
1124991002165	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1124991002166	GTP binding site; other site
1124991002167	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1124991002168	Walker A motif; other site
1124991002169	Protein of unknown function (DUF1040); Region: DUF1040; cl01176
1124991002170	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1124991002171	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1124991002172	active site
1124991002173	substrate binding site [chemical binding]; other site
1124991002174	ATP binding site [chemical binding]; other site
1124991002175	Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178
1124991002176	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1124991002177	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1124991002178	catalytic residues [active]
1124991002179	hinge region; other site
1124991002180	alpha helical domain; other site
1124991002181	DNA polymerase I; Provisional; Region: PRK05755
1124991002182	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1124991002183	active site
1124991002184	metal binding site 1 [ion binding]; metal-binding site
1124991002185	putative 5' ssDNA interaction site; other site
1124991002186	metal binding site 3; metal-binding site
1124991002187	metal binding site 2 [ion binding]; metal-binding site
1124991002188	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1124991002189	putative DNA binding site [nucleotide binding]; other site
1124991002190	putative metal binding site [ion binding]; other site
1124991002191	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1124991002192	active site
1124991002193	catalytic site [active]
1124991002194	substrate binding site [chemical binding]; other site
1124991002195	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1124991002196	active site
1124991002197	DNA binding site [nucleotide binding]
1124991002198	catalytic site [active]
1124991002199	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1124991002200	active site
1124991002201	catalytic residues [active]
1124991002202	metal binding site [ion binding]; metal-binding site
1124991002203	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1124991002204	G1 box; other site
1124991002205	GTP/Mg2+ binding site [chemical binding]; other site
1124991002206	Switch I region; other site
1124991002207	G2 box; other site
1124991002208	G3 box; other site
1124991002209	Switch II region; other site
1124991002210	G4 box; other site
1124991002211	G5 box; other site
1124991002212	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1124991002213	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1124991002214	substrate binding site [chemical binding]; other site
1124991002215	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1124991002216	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1124991002217	glutamine binding [chemical binding]; other site
1124991002218	catalytic triad [active]
1124991002219	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1124991002220	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1124991002221	inhibitor-cofactor binding pocket; inhibition site
1124991002222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991002223	catalytic residue [active]
1124991002224	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1124991002225	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1124991002226	ligand binding site [chemical binding]; other site
1124991002227	flexible hinge region; other site
1124991002228	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1124991002229	putative switch regulator; other site
1124991002230	non-specific DNA interactions [nucleotide binding]; other site
1124991002231	DNA binding site [nucleotide binding]
1124991002232	sequence specific DNA binding site [nucleotide binding]; other site
1124991002233	putative cAMP binding site [chemical binding]; other site
1124991002234	hypothetical protein; Provisional; Region: PRK10738
1124991002235	phosphoribulokinase; Provisional; Region: PRK15453
1124991002236	active site
1124991002237	hypothetical protein; Provisional; Region: PRK04966
1124991002238	putative hydrolase; Provisional; Region: PRK10985
1124991002239	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1124991002240	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1124991002241	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1124991002242	active site turn [active]
1124991002243	phosphorylation site [posttranslational modification]
1124991002244	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1124991002245	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1124991002246	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1124991002247	putative active site [active]
1124991002248	transcriptional regulator MurR; Provisional; Region: PRK15482
1124991002249	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1124991002250	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1124991002251	putative active site [active]
1124991002252	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1124991002253	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991002254	Walker A/P-loop; other site
1124991002255	ATP binding site [chemical binding]; other site
1124991002256	Q-loop/lid; other site
1124991002257	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991002258	ABC transporter signature motif; other site
1124991002259	Walker B; other site
1124991002260	D-loop; other site
1124991002261	ABC transporter; Region: ABC_tran_2; pfam12848
1124991002262	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991002263	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1124991002264	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1124991002265	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1124991002266	TrkA-N domain; Region: TrkA_N; pfam02254
1124991002267	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1124991002268	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
1124991002269	SlyX; Region: SlyX; pfam04102
1124991002270	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1124991002271	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1124991002272	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1124991002273	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1124991002274	YheO-like PAS domain; Region: PAS_6; pfam08348
1124991002275	HTH domain; Region: HTH_22; pfam13309
1124991002276	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1124991002277	sulfur relay protein TusC; Validated; Region: PRK00211
1124991002278	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1124991002279	S17 interaction site [polypeptide binding]; other site
1124991002280	S8 interaction site; other site
1124991002281	16S rRNA interaction site [nucleotide binding]; other site
1124991002282	streptomycin interaction site [chemical binding]; other site
1124991002283	23S rRNA interaction site [nucleotide binding]; other site
1124991002284	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1124991002285	30S ribosomal protein S7; Validated; Region: PRK05302
1124991002286	elongation factor G; Reviewed; Region: PRK00007
1124991002287	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1124991002288	G1 box; other site
1124991002289	putative GEF interaction site [polypeptide binding]; other site
1124991002290	GTP/Mg2+ binding site [chemical binding]; other site
1124991002291	Switch I region; other site
1124991002292	G2 box; other site
1124991002293	G3 box; other site
1124991002294	Switch II region; other site
1124991002295	G4 box; other site
1124991002296	G5 box; other site
1124991002297	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1124991002298	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1124991002299	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1124991002300	elongation factor Tu; Reviewed; Region: PRK00049
1124991002301	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1124991002302	G1 box; other site
1124991002303	GEF interaction site [polypeptide binding]; other site
1124991002304	GTP/Mg2+ binding site [chemical binding]; other site
1124991002305	Switch I region; other site
1124991002306	G2 box; other site
1124991002307	G3 box; other site
1124991002308	Switch II region; other site
1124991002309	G4 box; other site
1124991002310	G5 box; other site
1124991002311	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1124991002312	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1124991002313	Antibiotic Binding Site [chemical binding]; other site
1124991002314	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1124991002315	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1124991002316	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1124991002317	putative homodimer interface [polypeptide binding]; other site
1124991002318	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1124991002319	heterodimer interface [polypeptide binding]; other site
1124991002320	homodimer interface [polypeptide binding]; other site
1124991002321	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1124991002322	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1124991002323	23S rRNA interface [nucleotide binding]; other site
1124991002324	L7/L12 interface [polypeptide binding]; other site
1124991002325	putative thiostrepton binding site; other site
1124991002326	L25 interface [polypeptide binding]; other site
1124991002327	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1124991002328	mRNA/rRNA interface [nucleotide binding]; other site
1124991002329	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1124991002330	23S rRNA interface [nucleotide binding]; other site
1124991002331	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1124991002332	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1124991002333	core dimer interface [polypeptide binding]; other site
1124991002334	peripheral dimer interface [polypeptide binding]; other site
1124991002335	L10 interface [polypeptide binding]; other site
1124991002336	L11 interface [polypeptide binding]; other site
1124991002337	putative EF-Tu interaction site [polypeptide binding]; other site
1124991002338	putative EF-G interaction site [polypeptide binding]; other site
1124991002339	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1124991002340	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1124991002341	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1124991002342	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1124991002343	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1124991002344	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1124991002345	RPB3 interaction site [polypeptide binding]; other site
1124991002346	RPB1 interaction site [polypeptide binding]; other site
1124991002347	RPB11 interaction site [polypeptide binding]; other site
1124991002348	RPB10 interaction site [polypeptide binding]; other site
1124991002349	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1124991002350	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1124991002351	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1124991002352	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1124991002353	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1124991002354	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1124991002355	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1124991002356	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1124991002357	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1124991002358	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1124991002359	DNA binding site [nucleotide binding]
1124991002360	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1124991002361	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1124991002362	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1124991002363	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1124991002364	DNA binding residues [nucleotide binding]
1124991002365	drug binding residues [chemical binding]; other site
1124991002366	dimer interface [polypeptide binding]; other site
1124991002367	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1124991002368	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1124991002369	homodimer interface [polypeptide binding]; other site
1124991002370	substrate-cofactor binding pocket; other site
1124991002371	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991002372	catalytic residue [active]
1124991002373	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1124991002374	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1124991002375	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1124991002376	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991002377	FeS/SAM binding site; other site
1124991002378	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1124991002379	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1124991002380	ThiS interaction site; other site
1124991002381	putative active site [active]
1124991002382	tetramer interface [polypeptide binding]; other site
1124991002383	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1124991002384	thiS-thiF/thiG interaction site; other site
1124991002385	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1124991002386	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1124991002387	ATP binding site [chemical binding]; other site
1124991002388	substrate interface [chemical binding]; other site
1124991002389	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1124991002390	thiamine phosphate binding site [chemical binding]; other site
1124991002391	active site
1124991002392	pyrophosphate binding site [ion binding]; other site
1124991002393	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1124991002394	ThiC-associated domain; Region: ThiC-associated; pfam13667
1124991002395	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1124991002396	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1124991002397	HAMP domain; Region: HAMP; pfam00672
1124991002398	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1124991002399	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991002400	dimer interface [polypeptide binding]; other site
1124991002401	putative CheW interface [polypeptide binding]; other site
1124991002402	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1124991002403	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991002404	motif II; other site
1124991002405	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1124991002406	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991002407	Walker A/P-loop; other site
1124991002408	ATP binding site [chemical binding]; other site
1124991002409	Q-loop/lid; other site
1124991002410	ABC transporter signature motif; other site
1124991002411	Walker B; other site
1124991002412	D-loop; other site
1124991002413	H-loop/switch region; other site
1124991002414	TOBE domain; Region: TOBE_2; pfam08402
1124991002415	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1124991002416	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002417	dimer interface [polypeptide binding]; other site
1124991002418	conserved gate region; other site
1124991002419	putative PBP binding loops; other site
1124991002420	ABC-ATPase subunit interface; other site
1124991002421	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002422	dimer interface [polypeptide binding]; other site
1124991002423	conserved gate region; other site
1124991002424	putative PBP binding loops; other site
1124991002425	ABC-ATPase subunit interface; other site
1124991002426	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1124991002427	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1124991002428	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1124991002429	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1124991002430	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1124991002431	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1124991002432	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1124991002433	putative NADH binding site [chemical binding]; other site
1124991002434	putative active site [active]
1124991002435	nudix motif; other site
1124991002436	putative metal binding site [ion binding]; other site
1124991002437	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1124991002438	substrate binding site [chemical binding]; other site
1124991002439	active site
1124991002440	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1124991002441	Active_site [active]
1124991002442	Protein of unknown function (DUF416); Region: DUF416; cl01166
1124991002443	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1124991002444	IHF dimer interface [polypeptide binding]; other site
1124991002445	IHF - DNA interface [nucleotide binding]; other site
1124991002446	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1124991002447	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1124991002448	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1124991002449	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1124991002450	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1124991002451	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1124991002452	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1124991002453	purine monophosphate binding site [chemical binding]; other site
1124991002454	dimer interface [polypeptide binding]; other site
1124991002455	putative catalytic residues [active]
1124991002456	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1124991002457	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1124991002458	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1124991002459	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1124991002460	proposed active site lysine [active]
1124991002461	conserved cys residue [active]
1124991002462	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1124991002463	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1124991002464	active site
1124991002465	intersubunit interface [polypeptide binding]; other site
1124991002466	catalytic residue [active]
1124991002467	phosphogluconate dehydratase; Validated; Region: PRK09054
1124991002468	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1124991002469	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1124991002470	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1124991002471	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1124991002472	substrate binding pocket [chemical binding]; other site
1124991002473	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1124991002474	B12 binding site [chemical binding]; other site
1124991002475	cobalt ligand [ion binding]; other site
1124991002476	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1124991002477	aspartate kinase III; Validated; Region: PRK09084
1124991002478	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1124991002479	nucleotide binding site [chemical binding]; other site
1124991002480	substrate binding site [chemical binding]; other site
1124991002481	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1124991002482	lysine allosteric regulatory site; other site
1124991002483	dimer interface [polypeptide binding]; other site
1124991002484	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1124991002485	dimer interface [polypeptide binding]; other site
1124991002486	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1124991002487	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1124991002488	active site
1124991002489	dimer interface [polypeptide binding]; other site
1124991002490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1124991002491	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1124991002492	dimer interface [polypeptide binding]; other site
1124991002493	active site
1124991002494	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1124991002495	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1124991002496	UbiA prenyltransferase family; Region: UbiA; pfam01040
1124991002497	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1124991002498	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1124991002499	putative acyl-acceptor binding pocket; other site
1124991002500	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1124991002501	LexA repressor; Validated; Region: PRK00215
1124991002502	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1124991002503	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991002504	Catalytic site [active]
1124991002505	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1124991002506	metal binding site 2 [ion binding]; metal-binding site
1124991002507	putative DNA binding helix; other site
1124991002508	metal binding site 1 [ion binding]; metal-binding site
1124991002509	dimer interface [polypeptide binding]; other site
1124991002510	structural Zn2+ binding site [ion binding]; other site
1124991002511	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1124991002512	putative deacylase active site [active]
1124991002513	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991002514	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991002515	non-specific DNA binding site [nucleotide binding]; other site
1124991002516	salt bridge; other site
1124991002517	sequence-specific DNA binding site [nucleotide binding]; other site
1124991002518	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991002519	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991002520	non-specific DNA binding site [nucleotide binding]; other site
1124991002521	salt bridge; other site
1124991002522	sequence-specific DNA binding site [nucleotide binding]; other site
1124991002523	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1124991002524	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991002525	putative substrate translocation pore; other site
1124991002526	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1124991002527	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1124991002528	FMN binding site [chemical binding]; other site
1124991002529	active site
1124991002530	catalytic residues [active]
1124991002531	substrate binding site [chemical binding]; other site
1124991002532	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1124991002533	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1124991002534	NADP binding site [chemical binding]; other site
1124991002535	dimer interface [polypeptide binding]; other site
1124991002536	replicative DNA helicase; Provisional; Region: PRK08006
1124991002537	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1124991002538	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1124991002539	Walker A motif; other site
1124991002540	ATP binding site [chemical binding]; other site
1124991002541	Walker B motif; other site
1124991002542	DNA binding loops [nucleotide binding]
1124991002543	alanine racemase; Reviewed; Region: alr; PRK00053
1124991002544	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1124991002545	active site
1124991002546	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1124991002547	substrate binding site [chemical binding]; other site
1124991002548	catalytic residues [active]
1124991002549	dimer interface [polypeptide binding]; other site
1124991002550	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1124991002551	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991002552	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991002553	homodimer interface [polypeptide binding]; other site
1124991002554	catalytic residue [active]
1124991002555	hypothetical protein; Provisional; Region: PRK11019
1124991002556	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1124991002557	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1124991002558	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1124991002559	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1124991002560	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1124991002561	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1124991002562	dimer interface [polypeptide binding]; other site
1124991002563	ssDNA binding site [nucleotide binding]; other site
1124991002564	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1124991002565	putative single-stranded DNA-binding protein; Region: PHA01740
1124991002566	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1124991002567	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1124991002568	PYR/PP interface [polypeptide binding]; other site
1124991002569	dimer interface [polypeptide binding]; other site
1124991002570	TPP binding site [chemical binding]; other site
1124991002571	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991002572	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1124991002573	TPP-binding site [chemical binding]; other site
1124991002574	dimer interface [polypeptide binding]; other site
1124991002575	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1124991002576	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1124991002577	putative valine binding site [chemical binding]; other site
1124991002578	dimer interface [polypeptide binding]; other site
1124991002579	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991002580	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991002581	non-specific DNA binding site [nucleotide binding]; other site
1124991002582	salt bridge; other site
1124991002583	sequence-specific DNA binding site [nucleotide binding]; other site
1124991002584	Cupin domain; Region: Cupin_2; cl17218
1124991002585	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991002586	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1124991002587	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1124991002588	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1124991002589	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1124991002590	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1124991002591	EamA-like transporter family; Region: EamA; pfam00892
1124991002592	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1124991002593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991002594	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1124991002595	putative dimerization interface [polypeptide binding]; other site
1124991002596	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1124991002597	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1124991002598	THF binding site; other site
1124991002599	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1124991002600	substrate binding site [chemical binding]; other site
1124991002601	THF binding site; other site
1124991002602	zinc-binding site [ion binding]; other site
1124991002603	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1124991002604	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1124991002605	hypothetical protein; Reviewed; Region: PRK09588
1124991002606	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1124991002607	uridine phosphorylase; Provisional; Region: PRK11178
1124991002608	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1124991002609	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1124991002610	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1124991002611	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1124991002612	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1124991002613	DNA recombination protein RmuC; Provisional; Region: PRK10361
1124991002614	RmuC family; Region: RmuC; pfam02646
1124991002615	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1124991002616	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991002617	S-adenosylmethionine binding site [chemical binding]; other site
1124991002618	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1124991002619	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1124991002620	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1124991002621	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1124991002622	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1124991002623	twin arginine translocase protein A; Provisional; Region: tatA; PRK04598
1124991002624	sec-independent translocase; Provisional; Region: PRK01770
1124991002625	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1124991002626	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1124991002627	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1124991002628	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1124991002629	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1124991002630	active site pocket [active]
1124991002631	oxyanion hole [active]
1124991002632	catalytic triad [active]
1124991002633	active site nucleophile [active]
1124991002634	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1124991002635	FMN reductase; Validated; Region: fre; PRK08051
1124991002636	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1124991002637	FAD binding pocket [chemical binding]; other site
1124991002638	FAD binding motif [chemical binding]; other site
1124991002639	phosphate binding motif [ion binding]; other site
1124991002640	beta-alpha-beta structure motif; other site
1124991002641	NAD binding pocket [chemical binding]; other site
1124991002642	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1124991002643	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1124991002644	dimer interface [polypeptide binding]; other site
1124991002645	active site
1124991002646	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1124991002647	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1124991002648	substrate binding site [chemical binding]; other site
1124991002649	oxyanion hole (OAH) forming residues; other site
1124991002650	trimer interface [polypeptide binding]; other site
1124991002651	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1124991002652	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1124991002653	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1124991002654	proline dipeptidase; Provisional; Region: PRK13607
1124991002655	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1124991002656	active site
1124991002657	hypothetical protein; Provisional; Region: PRK11568
1124991002658	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1124991002659	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1124991002660	Cation transport protein; Region: TrkH; cl17365
1124991002661	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1124991002662	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1124991002663	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
1124991002664	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1124991002665	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1124991002666	Predicted membrane protein [Function unknown]; Region: COG4125
1124991002667	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1124991002668	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1124991002669	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991002670	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991002671	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1124991002672	dimerization interface [polypeptide binding]; other site
1124991002673	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1124991002674	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991002675	Walker A/P-loop; other site
1124991002676	ATP binding site [chemical binding]; other site
1124991002677	Q-loop/lid; other site
1124991002678	ABC transporter signature motif; other site
1124991002679	Walker B; other site
1124991002680	D-loop; other site
1124991002681	H-loop/switch region; other site
1124991002682	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1124991002683	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1124991002684	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1124991002685	alkaline phosphatase; Provisional; Region: PRK10518
1124991002686	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1124991002687	dimer interface [polypeptide binding]; other site
1124991002688	active site
1124991002689	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1124991002690	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1124991002691	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1124991002692	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1124991002693	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991002694	S-adenosylmethionine binding site [chemical binding]; other site
1124991002695	DNA polymerase III subunit psi; Validated; Region: PRK06856
1124991002696	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1124991002697	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991002698	Coenzyme A binding pocket [chemical binding]; other site
1124991002699	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1124991002700	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1124991002701	G1 box; other site
1124991002702	putative GEF interaction site [polypeptide binding]; other site
1124991002703	GTP/Mg2+ binding site [chemical binding]; other site
1124991002704	Switch I region; other site
1124991002705	G2 box; other site
1124991002706	G3 box; other site
1124991002707	Switch II region; other site
1124991002708	G4 box; other site
1124991002709	G5 box; other site
1124991002710	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1124991002711	periplasmic protein; Provisional; Region: PRK10568
1124991002712	BON domain; Region: BON; pfam04972
1124991002713	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1124991002714	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1124991002715	active site
1124991002716	nucleophile elbow; other site
1124991002717	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1124991002718	active site
1124991002719	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1124991002720	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1124991002721	Nucleoside recognition; Region: Gate; pfam07670
1124991002722	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1124991002723	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1124991002724	intersubunit interface [polypeptide binding]; other site
1124991002725	active site
1124991002726	catalytic residue [active]
1124991002727	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1124991002728	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1124991002729	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1124991002730	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1124991002731	phosphopentomutase; Provisional; Region: PRK05362
1124991002732	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1124991002733	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1124991002734	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1124991002735	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1124991002736	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1124991002737	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991002738	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1124991002739	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991002740	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1124991002741	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1124991002742	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1124991002743	Secretin and TonB N terminus short domain; Region: STN; smart00965
1124991002744	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1124991002745	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1124991002746	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
1124991002747	FecR protein; Region: FecR; pfam04773
1124991002748	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991002749	RNA polymerase sigma factor; Reviewed; Region: PRK12527
1124991002750	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991002751	DNA binding residues [nucleotide binding]
1124991002752	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1124991002753	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1124991002754	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1124991002755	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1124991002756	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1124991002757	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002758	dimer interface [polypeptide binding]; other site
1124991002759	conserved gate region; other site
1124991002760	putative PBP binding loops; other site
1124991002761	ABC-ATPase subunit interface; other site
1124991002762	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1124991002763	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991002764	dimer interface [polypeptide binding]; other site
1124991002765	conserved gate region; other site
1124991002766	putative PBP binding loops; other site
1124991002767	ABC-ATPase subunit interface; other site
1124991002768	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1124991002769	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991002770	Walker A/P-loop; other site
1124991002771	ATP binding site [chemical binding]; other site
1124991002772	Q-loop/lid; other site
1124991002773	ABC transporter signature motif; other site
1124991002774	Walker B; other site
1124991002775	D-loop; other site
1124991002776	H-loop/switch region; other site
1124991002777	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1124991002778	alpha-gamma subunit interface [polypeptide binding]; other site
1124991002779	beta-gamma subunit interface [polypeptide binding]; other site
1124991002780	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1124991002781	alpha-beta subunit interface [polypeptide binding]; other site
1124991002782	urease subunit alpha; Reviewed; Region: ureC; PRK13309
1124991002783	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1124991002784	subunit interactions [polypeptide binding]; other site
1124991002785	active site
1124991002786	flap region; other site
1124991002787	urease accessory protein UreE; Provisional; Region: ureE; PRK14711
1124991002788	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1124991002789	dimer interface [polypeptide binding]; other site
1124991002790	catalytic residues [active]
1124991002791	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1124991002792	UreF; Region: UreF; pfam01730
1124991002793	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1124991002794	G1 box; other site
1124991002795	GTP/Mg2+ binding site [chemical binding]; other site
1124991002796	G2 box; other site
1124991002797	Switch I region; other site
1124991002798	G3 box; other site
1124991002799	Switch II region; other site
1124991002800	G4 box; other site
1124991002801	G5 box; other site
1124991002802	UreD urease accessory protein; Region: UreD; pfam01774
1124991002803	Urea transporter; Region: UT; cl01829
1124991002804	voltage-gated potassium channel; Provisional; Region: PRK10537
1124991002805	Ion channel; Region: Ion_trans_2; pfam07885
1124991002806	TrkA-N domain; Region: TrkA_N; pfam02254
1124991002807	Predicted membrane protein [Function unknown]; Region: COG1289
1124991002808	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1124991002809	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1124991002810	chromosome condensation membrane protein; Provisional; Region: PRK14196
1124991002811	hypothetical protein; Provisional; Region: PRK11246
1124991002812	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1124991002813	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991002814	motif II; other site
1124991002815	DNA repair protein RadA; Provisional; Region: PRK11823
1124991002816	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1124991002817	Walker A motif/ATP binding site; other site
1124991002818	ATP binding site [chemical binding]; other site
1124991002819	Walker B motif; other site
1124991002820	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1124991002821	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991002822	non-specific DNA binding site [nucleotide binding]; other site
1124991002823	salt bridge; other site
1124991002824	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1124991002825	sequence-specific DNA binding site [nucleotide binding]; other site
1124991002826	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1124991002827	active site
1124991002828	nucleotide binding site [chemical binding]; other site
1124991002829	HIGH motif; other site
1124991002830	KMSKS motif; other site
1124991002831	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1124991002832	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1124991002833	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991002834	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991002835	ABC transporter; Region: ABC_tran_2; pfam12848
1124991002836	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991002837	lytic murein transglycosylase; Provisional; Region: PRK11619
1124991002838	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1124991002839	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1124991002840	catalytic residue [active]
1124991002841	Trp operon repressor; Provisional; Region: PRK01381
1124991002842	Helix-turn-helix domain; Region: HTH_18; pfam12833
1124991002843	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991002844	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1124991002845	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991002846	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1124991002847	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1124991002848	catalytic core [active]
1124991002849	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1124991002850	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991002851	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1124991002852	hypothetical protein; Provisional; Region: PRK10756
1124991002853	CreA protein; Region: CreA; pfam05981
1124991002854	two-component response regulator; Provisional; Region: PRK11173
1124991002855	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991002856	active site
1124991002857	phosphorylation site [posttranslational modification]
1124991002858	intermolecular recognition site; other site
1124991002859	dimerization interface [polypeptide binding]; other site
1124991002860	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991002861	DNA binding site [nucleotide binding]
1124991002862	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1124991002863	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1124991002864	putative catalytic residues [active]
1124991002865	putative nucleotide binding site [chemical binding]; other site
1124991002866	putative aspartate binding site [chemical binding]; other site
1124991002867	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1124991002868	dimer interface [polypeptide binding]; other site
1124991002869	putative threonine allosteric regulatory site; other site
1124991002870	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1124991002871	putative threonine allosteric regulatory site; other site
1124991002872	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1124991002873	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1124991002874	homoserine kinase; Provisional; Region: PRK01212
1124991002875	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1124991002876	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1124991002877	threonine synthase; Validated; Region: PRK09225
1124991002878	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1124991002879	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991002880	catalytic residue [active]
1124991002881	hypothetical protein; Validated; Region: PRK02101
1124991002882	transaldolase-like protein; Provisional; Region: PTZ00411
1124991002883	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1124991002884	active site
1124991002885	dimer interface [polypeptide binding]; other site
1124991002886	catalytic residue [active]
1124991002887	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1124991002888	MPT binding site; other site
1124991002889	trimer interface [polypeptide binding]; other site
1124991002890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991002891	metabolite-proton symporter; Region: 2A0106; TIGR00883
1124991002892	putative substrate translocation pore; other site
1124991002893	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1124991002894	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991002895	nucleotide binding site [chemical binding]; other site
1124991002896	chaperone protein DnaJ; Provisional; Region: PRK10767
1124991002897	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1124991002898	HSP70 interaction site [polypeptide binding]; other site
1124991002899	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1124991002900	substrate binding site [polypeptide binding]; other site
1124991002901	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1124991002902	Zn binding sites [ion binding]; other site
1124991002903	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1124991002904	dimer interface [polypeptide binding]; other site
1124991002905	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1124991002906	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1124991002907	EamA-like transporter family; Region: EamA; pfam00892
1124991002908	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1124991002909	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1124991002910	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991002911	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1124991002912	putative dimerization interface [polypeptide binding]; other site
1124991002913	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1124991002914	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1124991002915	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1124991002916	active site
1124991002917	Riboflavin kinase; Region: Flavokinase; smart00904
1124991002918	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1124991002919	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1124991002920	active site
1124991002921	HIGH motif; other site
1124991002922	nucleotide binding site [chemical binding]; other site
1124991002923	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1124991002924	active site
1124991002925	KMSKS motif; other site
1124991002926	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1124991002927	tRNA binding surface [nucleotide binding]; other site
1124991002928	anticodon binding site; other site
1124991002929	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1124991002930	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1124991002931	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1124991002932	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1124991002933	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1124991002934	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1124991002935	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1124991002936	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1124991002937	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1124991002938	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1124991002939	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1124991002940	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1124991002941	catalytic site [active]
1124991002942	subunit interface [polypeptide binding]; other site
1124991002943	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1124991002944	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1124991002945	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1124991002946	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1124991002947	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1124991002948	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1124991002949	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1124991002950	IMP binding site; other site
1124991002951	dimer interface [polypeptide binding]; other site
1124991002952	interdomain contacts; other site
1124991002953	partial ornithine binding site; other site
1124991002954	YadA-like C-terminal region; Region: YadA; pfam03895
1124991002955	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1124991002956	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1124991002957	active site
1124991002958	catalytic tetrad [active]
1124991002959	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1124991002960	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1124991002961	dimer interface [polypeptide binding]; other site
1124991002962	active site
1124991002963	metal binding site [ion binding]; metal-binding site
1124991002964	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1124991002965	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1124991002966	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1124991002967	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1124991002968	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1124991002969	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1124991002970	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1124991002971	active site
1124991002972	NTP binding site [chemical binding]; other site
1124991002973	metal binding triad [ion binding]; metal-binding site
1124991002974	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1124991002975	SH3 domain-containing protein; Provisional; Region: PRK10884
1124991002976	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1124991002977	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1124991002978	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1124991002979	putative active site [active]
1124991002980	putative metal binding residues [ion binding]; other site
1124991002981	signature motif; other site
1124991002982	putative triphosphate binding site [ion binding]; other site
1124991002983	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1124991002984	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1124991002985	metal binding triad; other site
1124991002986	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1124991002987	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1124991002988	metal binding triad; other site
1124991002989	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1124991002990	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1124991002991	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1124991002992	putative ribose interaction site [chemical binding]; other site
1124991002993	putative ADP binding site [chemical binding]; other site
1124991002994	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1124991002995	active site
1124991002996	HIGH motif; other site
1124991002997	nucleotide binding site [chemical binding]; other site
1124991002998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1124991002999	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1124991003000	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1124991003001	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1124991003002	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1124991003003	putative active site [active]
1124991003004	metal binding site [ion binding]; metal-binding site
1124991003005	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1124991003006	Protein of unknown function (DUF1190); Region: DUF1190; cl10031
1124991003007	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1124991003008	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1124991003009	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1124991003010	dimer interface [polypeptide binding]; other site
1124991003011	ADP-ribose binding site [chemical binding]; other site
1124991003012	active site
1124991003013	nudix motif; other site
1124991003014	metal binding site [ion binding]; metal-binding site
1124991003015	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1124991003016	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1124991003017	active site
1124991003018	metal binding site [ion binding]; metal-binding site
1124991003019	hexamer interface [polypeptide binding]; other site
1124991003020	esterase YqiA; Provisional; Region: PRK11071
1124991003021	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1124991003022	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1124991003023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991003024	ATP binding site [chemical binding]; other site
1124991003025	Mg2+ binding site [ion binding]; other site
1124991003026	G-X-G motif; other site
1124991003027	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1124991003028	anchoring element; other site
1124991003029	dimer interface [polypeptide binding]; other site
1124991003030	ATP binding site [chemical binding]; other site
1124991003031	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1124991003032	active site
1124991003033	metal binding site [ion binding]; metal-binding site
1124991003034	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1124991003035	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1124991003036	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1124991003037	CAP-like domain; other site
1124991003038	active site
1124991003039	primary dimer interface [polypeptide binding]; other site
1124991003040	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1124991003041	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1124991003042	putative acyl-acceptor binding pocket; other site
1124991003043	FtsI repressor; Provisional; Region: PRK10883
1124991003044	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1124991003045	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1124991003046	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1124991003047	active site
1124991003048	NTP binding site [chemical binding]; other site
1124991003049	metal binding triad [ion binding]; metal-binding site
1124991003050	LysE type translocator; Region: LysE; cl00565
1124991003051	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1124991003052	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1124991003053	folate binding site [chemical binding]; other site
1124991003054	NADP+ binding site [chemical binding]; other site
1124991003055	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1124991003056	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1124991003057	active site
1124991003058	metal binding site [ion binding]; metal-binding site
1124991003059	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1124991003060	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1124991003061	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1124991003062	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1124991003063	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1124991003064	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1124991003065	SurA N-terminal domain; Region: SurA_N; pfam09312
1124991003066	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1124991003067	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1124991003068	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1124991003069	OstA-like protein; Region: OstA; pfam03968
1124991003070	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1124991003071	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1124991003072	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1124991003073	putative metal binding site [ion binding]; other site
1124991003074	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1124991003075	HSP70 interaction site [polypeptide binding]; other site
1124991003076	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1124991003077	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1124991003078	active site
1124991003079	ATP-dependent helicase HepA; Validated; Region: PRK04914
1124991003080	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991003081	ATP binding site [chemical binding]; other site
1124991003082	putative Mg++ binding site [ion binding]; other site
1124991003083	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991003084	nucleotide binding region [chemical binding]; other site
1124991003085	ATP-binding site [chemical binding]; other site
1124991003086	DNA polymerase II; Reviewed; Region: PRK05762
1124991003087	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1124991003088	active site
1124991003089	catalytic site [active]
1124991003090	substrate binding site [chemical binding]; other site
1124991003091	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1124991003092	active site
1124991003093	metal-binding site
1124991003094	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1124991003095	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991003096	Walker A/P-loop; other site
1124991003097	ATP binding site [chemical binding]; other site
1124991003098	Q-loop/lid; other site
1124991003099	ABC transporter signature motif; other site
1124991003100	Walker B; other site
1124991003101	D-loop; other site
1124991003102	H-loop/switch region; other site
1124991003103	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1124991003104	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991003105	dimer interface [polypeptide binding]; other site
1124991003106	conserved gate region; other site
1124991003107	putative PBP binding loops; other site
1124991003108	ABC-ATPase subunit interface; other site
1124991003109	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991003110	dimer interface [polypeptide binding]; other site
1124991003111	conserved gate region; other site
1124991003112	putative PBP binding loops; other site
1124991003113	ABC-ATPase subunit interface; other site
1124991003114	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1124991003115	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1124991003116	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1124991003117	putative active site [active]
1124991003118	Ap4A binding site [chemical binding]; other site
1124991003119	nudix motif; other site
1124991003120	putative metal binding site [ion binding]; other site
1124991003121	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1124991003122	GAF domain; Region: GAF; pfam01590
1124991003123	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1124991003124	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1124991003125	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1124991003126	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1124991003127	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1124991003128	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1124991003129	dimerization interface [polypeptide binding]; other site
1124991003130	active site
1124991003131	hypothetical protein; Provisional; Region: PRK10506
1124991003132	hypothetical protein; Provisional; Region: PRK10557
1124991003133	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
1124991003134	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1124991003135	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1124991003136	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1124991003137	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1124991003138	protease3; Provisional; Region: PRK15101
1124991003139	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1124991003140	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991003141	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991003142	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1124991003143	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1124991003144	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1124991003145	AAA domain; Region: AAA_30; pfam13604
1124991003146	Family description; Region: UvrD_C_2; pfam13538
1124991003147	N-acetylglutamate synthase; Validated; Region: PRK05279
1124991003148	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1124991003149	putative feedback inhibition sensing region; other site
1124991003150	putative nucleotide binding site [chemical binding]; other site
1124991003151	putative substrate binding site [chemical binding]; other site
1124991003152	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991003153	Coenzyme A binding pocket [chemical binding]; other site
1124991003154	AMIN domain; Region: AMIN; pfam11741
1124991003155	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1124991003156	active site
1124991003157	metal binding site [ion binding]; metal-binding site
1124991003158	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1124991003159	MltA specific insert domain; Region: MltA; smart00925
1124991003160	3D domain; Region: 3D; pfam06725
1124991003161	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1124991003162	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1124991003163	putative ATP binding site [chemical binding]; other site
1124991003164	putative substrate interface [chemical binding]; other site
1124991003165	Fe-S metabolism associated domain; Region: SufE; cl00951
1124991003166	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1124991003167	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1124991003168	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991003169	catalytic residue [active]
1124991003170	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1124991003171	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991003172	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1124991003173	dimerization interface [polypeptide binding]; other site
1124991003174	substrate binding pocket [chemical binding]; other site
1124991003175	hypothetical protein; Provisional; Region: PRK10873
1124991003176	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1124991003177	FtsJ-like methyltransferase; Region: FtsJ; cl17430
1124991003178	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1124991003179	flap endonuclease-like protein; Provisional; Region: PRK09482
1124991003180	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1124991003181	active site
1124991003182	metal binding site 1 [ion binding]; metal-binding site
1124991003183	putative 5' ssDNA interaction site; other site
1124991003184	metal binding site 3; metal-binding site
1124991003185	metal binding site 2 [ion binding]; metal-binding site
1124991003186	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1124991003187	putative DNA binding site [nucleotide binding]; other site
1124991003188	putative metal binding site [ion binding]; other site
1124991003189	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1124991003190	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1124991003191	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1124991003192	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1124991003193	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1124991003194	SecY interacting protein Syd; Provisional; Region: PRK04968
1124991003195	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1124991003196	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1124991003197	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1124991003198	probable active site [active]
1124991003199	flavodoxin; Provisional; Region: PRK08105
1124991003200	hypothetical protein; Provisional; Region: PRK13677
1124991003201	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1124991003202	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1124991003203	active site
1124991003204	substrate binding site [chemical binding]; other site
1124991003205	trimer interface [polypeptide binding]; other site
1124991003206	CoA binding site [chemical binding]; other site
1124991003207	PII uridylyl-transferase; Provisional; Region: PRK05007
1124991003208	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1124991003209	metal binding triad; other site
1124991003210	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1124991003211	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1124991003212	Zn2+ binding site [ion binding]; other site
1124991003213	Mg2+ binding site [ion binding]; other site
1124991003214	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1124991003215	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1124991003216	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1124991003217	active site
1124991003218	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1124991003219	rRNA interaction site [nucleotide binding]; other site
1124991003220	S8 interaction site; other site
1124991003221	putative laminin-1 binding site; other site
1124991003222	elongation factor Ts; Provisional; Region: tsf; PRK09377
1124991003223	UBA/TS-N domain; Region: UBA; pfam00627
1124991003224	Elongation factor TS; Region: EF_TS; pfam00889
1124991003225	Elongation factor TS; Region: EF_TS; pfam00889
1124991003226	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1124991003227	putative nucleotide binding site [chemical binding]; other site
1124991003228	uridine monophosphate binding site [chemical binding]; other site
1124991003229	homohexameric interface [polypeptide binding]; other site
1124991003230	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1124991003231	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1124991003232	hinge region; other site
1124991003233	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1124991003234	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1124991003235	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1124991003236	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1124991003237	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1124991003238	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1124991003239	catalytic residue [active]
1124991003240	putative FPP diphosphate  binding site; other site
1124991003241	putative FPP binding hydrophobic cleft; other site
1124991003242	dimer interface [polypeptide binding]; other site
1124991003243	putative IPP diphosphate binding site; other site
1124991003244	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1124991003245	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1124991003246	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1124991003247	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1124991003248	active site
1124991003249	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1124991003250	protein binding site [polypeptide binding]; other site
1124991003251	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1124991003252	protein binding site [polypeptide binding]; other site
1124991003253	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1124991003254	putative substrate binding region [chemical binding]; other site
1124991003255	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1124991003256	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1124991003257	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1124991003258	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1124991003259	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1124991003260	Surface antigen; Region: Bac_surface_Ag; pfam01103
1124991003261	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
1124991003262	periplasmic chaperone; Provisional; Region: PRK10780
1124991003263	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1124991003264	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1124991003265	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1124991003266	trimer interface [polypeptide binding]; other site
1124991003267	active site
1124991003268	UDP-GlcNAc binding site [chemical binding]; other site
1124991003269	lipid binding site [chemical binding]; lipid-binding site
1124991003270	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1124991003271	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1124991003272	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1124991003273	active site
1124991003274	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1124991003275	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1124991003276	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1124991003277	RNA/DNA hybrid binding site [nucleotide binding]; other site
1124991003278	active site
1124991003279	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1124991003280	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1124991003281	putative active site [active]
1124991003282	putative PHP Thumb interface [polypeptide binding]; other site
1124991003283	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1124991003284	generic binding surface II; other site
1124991003285	generic binding surface I; other site
1124991003286	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1124991003287	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1124991003288	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1124991003289	TilS substrate binding domain; Region: TilS; pfam09179
1124991003290	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1124991003291	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1124991003292	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1124991003293	NlpE N-terminal domain; Region: NlpE; pfam04170
1124991003294	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1124991003295	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1124991003296	dimer interface [polypeptide binding]; other site
1124991003297	motif 1; other site
1124991003298	active site
1124991003299	motif 2; other site
1124991003300	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1124991003301	putative deacylase active site [active]
1124991003302	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1124991003303	active site
1124991003304	motif 3; other site
1124991003305	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1124991003306	anticodon binding site; other site
1124991003307	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1124991003308	homodimer interaction site [polypeptide binding]; other site
1124991003309	cofactor binding site; other site
1124991003310	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1124991003311	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1124991003312	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1124991003313	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991003314	dimer interface [polypeptide binding]; other site
1124991003315	conserved gate region; other site
1124991003316	ABC-ATPase subunit interface; other site
1124991003317	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1124991003318	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1124991003319	Walker A/P-loop; other site
1124991003320	ATP binding site [chemical binding]; other site
1124991003321	Q-loop/lid; other site
1124991003322	ABC transporter signature motif; other site
1124991003323	Walker B; other site
1124991003324	D-loop; other site
1124991003325	H-loop/switch region; other site
1124991003326	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1124991003327	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1124991003328	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991003329	active site
1124991003330	motif I; other site
1124991003331	motif II; other site
1124991003332	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1124991003333	hypothetical protein; Provisional; Region: PRK05421
1124991003334	putative catalytic site [active]
1124991003335	putative metal binding site [ion binding]; other site
1124991003336	putative phosphate binding site [ion binding]; other site
1124991003337	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1124991003338	putative proline-specific permease; Provisional; Region: proY; PRK10580
1124991003339	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1124991003340	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1124991003341	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1124991003342	active site
1124991003343	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1124991003344	Flavodoxin; Region: Flavodoxin_1; pfam00258
1124991003345	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1124991003346	FAD binding pocket [chemical binding]; other site
1124991003347	FAD binding motif [chemical binding]; other site
1124991003348	catalytic residues [active]
1124991003349	NAD binding pocket [chemical binding]; other site
1124991003350	phosphate binding motif [ion binding]; other site
1124991003351	beta-alpha-beta structure motif; other site
1124991003352	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1124991003353	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1124991003354	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1124991003355	substrate binding site; other site
1124991003356	dimer interface; other site
1124991003357	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1124991003358	homotrimer interaction site [polypeptide binding]; other site
1124991003359	zinc binding site [ion binding]; other site
1124991003360	CDP-binding sites; other site
1124991003361	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1124991003362	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1124991003363	Permutation of conserved domain; other site
1124991003364	active site
1124991003365	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1124991003366	hypothetical protein; Provisional; Region: PRK10318
1124991003367	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1124991003368	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1124991003369	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991003370	S-adenosylmethionine binding site [chemical binding]; other site
1124991003371	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1124991003372	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1124991003373	Peptidase family M23; Region: Peptidase_M23; pfam01551
1124991003374	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1124991003375	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1124991003376	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991003377	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1124991003378	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991003379	DNA binding residues [nucleotide binding]
1124991003380	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1124991003381	MutS domain I; Region: MutS_I; pfam01624
1124991003382	MutS domain II; Region: MutS_II; pfam05188
1124991003383	MutS domain III; Region: MutS_III; pfam05192
1124991003384	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1124991003385	Walker A/P-loop; other site
1124991003386	ATP binding site [chemical binding]; other site
1124991003387	Q-loop/lid; other site
1124991003388	ABC transporter signature motif; other site
1124991003389	Walker B; other site
1124991003390	D-loop; other site
1124991003391	H-loop/switch region; other site
1124991003392	Surface antigen; Region: Bac_surface_Ag; pfam01103
1124991003393	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
1124991003394	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991003395	Coenzyme A binding pocket [chemical binding]; other site
1124991003396	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1124991003397	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1124991003398	transmembrane helices; other site
1124991003399	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1124991003400	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991003401	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1124991003402	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991003403	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991003404	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1124991003405	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1124991003406	Serine hydrolase; Region: Ser_hydrolase; cl17834
1124991003407	LysE type translocator; Region: LysE; cl00565
1124991003408	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1124991003409	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1124991003410	fumarate hydratase; Provisional; Region: PRK15389
1124991003411	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1124991003412	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1124991003413	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1124991003414	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1124991003415	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1124991003416	Walker A motif; other site
1124991003417	homodimer interface [polypeptide binding]; other site
1124991003418	ATP binding site [chemical binding]; other site
1124991003419	hydroxycobalamin binding site [chemical binding]; other site
1124991003420	Walker B motif; other site
1124991003421	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1124991003422	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1124991003423	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991003424	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991003425	dimerization interface [polypeptide binding]; other site
1124991003426	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1124991003427	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1124991003428	putative dimer interface [polypeptide binding]; other site
1124991003429	active site pocket [active]
1124991003430	putative cataytic base [active]
1124991003431	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1124991003432	catalytic core [active]
1124991003433	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1124991003434	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1124991003435	homotrimer interface [polypeptide binding]; other site
1124991003436	Walker A motif; other site
1124991003437	GTP binding site [chemical binding]; other site
1124991003438	Walker B motif; other site
1124991003439	cobyric acid synthase; Provisional; Region: PRK00784
1124991003440	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1124991003441	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1124991003442	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1124991003443	catalytic triad [active]
1124991003444	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1124991003445	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1124991003446	Walker A/P-loop; other site
1124991003447	ATP binding site [chemical binding]; other site
1124991003448	Q-loop/lid; other site
1124991003449	ABC transporter signature motif; other site
1124991003450	Walker B; other site
1124991003451	D-loop; other site
1124991003452	H-loop/switch region; other site
1124991003453	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1124991003454	cobalt transport protein CbiN; Provisional; Region: PRK02898
1124991003455	cobalt transport protein CbiM; Validated; Region: PRK08319
1124991003456	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1124991003457	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1124991003458	active site
1124991003459	SAM binding site [chemical binding]; other site
1124991003460	homodimer interface [polypeptide binding]; other site
1124991003461	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1124991003462	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1124991003463	active site
1124991003464	C-terminal domain interface [polypeptide binding]; other site
1124991003465	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1124991003466	active site
1124991003467	N-terminal domain interface [polypeptide binding]; other site
1124991003468	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1124991003469	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1124991003470	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1124991003471	active site
1124991003472	SAM binding site [chemical binding]; other site
1124991003473	homodimer interface [polypeptide binding]; other site
1124991003474	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1124991003475	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1124991003476	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1124991003477	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1124991003478	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1124991003479	active site
1124991003480	SAM binding site [chemical binding]; other site
1124991003481	homodimer interface [polypeptide binding]; other site
1124991003482	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1124991003483	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469
1124991003484	S-adenosylmethionine binding site [chemical binding]; other site
1124991003485	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1124991003486	active site
1124991003487	putative homodimer interface [polypeptide binding]; other site
1124991003488	SAM binding site [chemical binding]; other site
1124991003489	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1124991003490	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1124991003491	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1124991003492	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1124991003493	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
1124991003494	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1124991003495	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1124991003496	catalytic triad [active]
1124991003497	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1124991003498	active site
1124991003499	SAM binding site [chemical binding]; other site
1124991003500	homodimer interface [polypeptide binding]; other site
1124991003501	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1124991003502	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991003503	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991003504	homodimer interface [polypeptide binding]; other site
1124991003505	catalytic residue [active]
1124991003506	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1124991003507	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1124991003508	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
1124991003509	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1124991003510	B12 binding domain of glutamate mutase (Glm). Glutamate mutase catalysis the conversion of (S)-glutamate with (2S,3S)-3-methylaspartate. The rearrangement reaction is initiated by the extraction of a hydrogen from the protein-bound substrate by a 5'...; Region: Glm_B12_BD; cd02072
1124991003511	B12 binding site [chemical binding]; other site
1124991003512	heterodimer interface [polypeptide binding]; other site
1124991003513	cobalt ligand [ion binding]; other site
1124991003514	conserved hypothetical protein; Region: glmL_fam; TIGR01319
1124991003515	Coenzyme B12-dependent glutamate mutase epsilon subunit-like family; contains proteins similar to Clostridium cochlearium glutamate mutase (Glm) and Streptomyces tendae Tu901 NikV. Glm catalyzes a carbon-skeleton rearrangement of L-glutamate to...; Region: Glm_e; cd00245
1124991003516	substrate binding site [chemical binding]; other site
1124991003517	B12 cofactor binding site [chemical binding]; other site
1124991003518	heterodimer (sigma-epsilon) interface [polypeptide binding]; other site
1124991003519	homodimer (epsilon-epsilon) interface [polypeptide binding]; other site
1124991003520	Methylaspartate ammonia-lyase [Amino acid transport and metabolism]; Region: Mal; COG3799
1124991003521	Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the...; Region: MAL; cd03314
1124991003522	dimer interface [polypeptide binding]; other site
1124991003523	active site
1124991003524	K+-transporting ATPase, c chain; Region: KdpC; cl00944
1124991003525	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
1124991003526	Domain of unknown function (DUF4387); Region: DUF4387; pfam14330
1124991003527	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1124991003528	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1124991003529	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1124991003530	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1124991003531	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991003532	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1124991003533	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1124991003534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991003535	putative substrate translocation pore; other site
1124991003536	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
1124991003537	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1124991003538	transcriptional regulator protein; Region: phnR; TIGR03337
1124991003539	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991003540	DNA-binding site [nucleotide binding]; DNA binding site
1124991003541	UTRA domain; Region: UTRA; pfam07702
1124991003542	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1124991003543	putative hexamer interface [polypeptide binding]; other site
1124991003544	putative hexagonal pore; other site
1124991003545	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1124991003546	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1124991003547	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1124991003548	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; cl00920
1124991003549	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1124991003550	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1124991003551	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1124991003552	Hexamer interface [polypeptide binding]; other site
1124991003553	Hexagonal pore residue; other site
1124991003554	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1124991003555	Hexamer/Pentamer interface [polypeptide binding]; other site
1124991003556	central pore; other site
1124991003557	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1124991003558	putative catalytic cysteine [active]
1124991003559	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1124991003560	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991003561	nucleotide binding site [chemical binding]; other site
1124991003562	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1124991003563	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1124991003564	active site
1124991003565	metal binding site [ion binding]; metal-binding site
1124991003566	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1124991003567	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1124991003568	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
1124991003569	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1124991003570	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1124991003571	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1124991003572	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1124991003573	putative hexamer interface [polypeptide binding]; other site
1124991003574	putative hexagonal pore; other site
1124991003575	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1124991003576	putative hexamer interface [polypeptide binding]; other site
1124991003577	putative hexagonal pore; other site
1124991003578	carboxysome structural protein EutK; Provisional; Region: PRK15466
1124991003579	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1124991003580	Hexamer interface [polypeptide binding]; other site
1124991003581	Hexagonal pore residue; other site
1124991003582	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1124991003583	SLBB domain; Region: SLBB; pfam10531
1124991003584	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1124991003585	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1124991003586	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1124991003587	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1124991003588	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1124991003589	putative hexamer interface [polypeptide binding]; other site
1124991003590	putative hexagonal pore; other site
1124991003591	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1124991003592	putative hexamer interface [polypeptide binding]; other site
1124991003593	putative hexagonal pore; other site
1124991003594	transcriptional regulator EutR; Provisional; Region: PRK10130
1124991003595	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991003596	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991003597	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1124991003598	active site
1124991003599	homotetramer interface [polypeptide binding]; other site
1124991003600	homodimer interface [polypeptide binding]; other site
1124991003601	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1124991003602	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991003603	N-terminal plug; other site
1124991003604	ligand-binding site [chemical binding]; other site
1124991003605	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
1124991003606	dimer interface [polypeptide binding]; other site
1124991003607	[2Fe-2S] cluster binding site [ion binding]; other site
1124991003608	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991003609	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1124991003610	intersubunit interface [polypeptide binding]; other site
1124991003611	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1124991003612	nudix motif; other site
1124991003613	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1124991003614	major vault protein; Provisional; Region: PTZ00491
1124991003615	NADH kinase; Region: PLN02929
1124991003616	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1124991003617	guanine deaminase; Provisional; Region: PRK09228
1124991003618	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1124991003619	active site
1124991003620	putative hypoxanthine oxidase; Provisional; Region: PRK09800
1124991003621	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1124991003622	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1124991003623	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1124991003624	putative oxidoreductase; Provisional; Region: PRK09799
1124991003625	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1124991003626	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
1124991003627	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1124991003628	active site
1124991003629	putative substrate binding pocket [chemical binding]; other site
1124991003630	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1124991003631	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1124991003632	phosphate binding site [ion binding]; other site
1124991003633	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991003634	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1124991003635	Ligand binding site; other site
1124991003636	metal-binding site
1124991003637	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1124991003638	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1124991003639	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1124991003640	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1124991003641	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
1124991003642	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1124991003643	manganese transport protein MntH; Reviewed; Region: PRK00701
1124991003644	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1124991003645	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1124991003646	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991003647	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1124991003648	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1124991003649	substrate binding site [chemical binding]; other site
1124991003650	catalytic Zn binding site [ion binding]; other site
1124991003651	NAD binding site [chemical binding]; other site
1124991003652	structural Zn binding site [ion binding]; other site
1124991003653	dimer interface [polypeptide binding]; other site
1124991003654	S-formylglutathione hydrolase; Region: PLN02442
1124991003655	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1124991003656	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1124991003657	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1124991003658	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991003659	putative substrate translocation pore; other site
1124991003660	conserved hypothetical protein; Region: TIGR02231
1124991003661	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
1124991003662	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
1124991003663	carbamate kinase; Reviewed; Region: PRK12686
1124991003664	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1124991003665	putative substrate binding site [chemical binding]; other site
1124991003666	homodimer interface [polypeptide binding]; other site
1124991003667	nucleotide binding site [chemical binding]; other site
1124991003668	nucleotide binding site [chemical binding]; other site
1124991003669	phenylhydantoinase; Validated; Region: PRK08323
1124991003670	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1124991003671	tetramer interface [polypeptide binding]; other site
1124991003672	active site
1124991003673	peptidase; Reviewed; Region: PRK13004
1124991003674	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1124991003675	putative metal binding site [ion binding]; other site
1124991003676	putative dimer interface [polypeptide binding]; other site
1124991003677	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1124991003678	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1124991003679	catalytic residue [active]
1124991003680	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1124991003681	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1124991003682	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1124991003683	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1124991003684	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1124991003685	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1124991003686	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991003687	Walker A motif; other site
1124991003688	ATP binding site [chemical binding]; other site
1124991003689	Walker B motif; other site
1124991003690	arginine finger; other site
1124991003691	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1124991003692	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1124991003693	dimer interface [polypeptide binding]; other site
1124991003694	FMN binding site [chemical binding]; other site
1124991003695	Predicted transcriptional regulators [Transcription]; Region: COG1733
1124991003696	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1124991003697	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
1124991003698	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991003699	catalytic loop [active]
1124991003700	iron binding site [ion binding]; other site
1124991003701	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1124991003702	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
1124991003703	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1124991003704	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1124991003705	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1124991003706	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1124991003707	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1124991003708	response regulator FixJ; Provisional; Region: fixJ; PRK09390
1124991003709	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991003710	active site
1124991003711	dimerization interface [polypeptide binding]; other site
1124991003712	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991003713	DNA binding residues [nucleotide binding]
1124991003714	dimerization interface [polypeptide binding]; other site
1124991003715	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1124991003716	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991003717	DNA binding site [nucleotide binding]
1124991003718	domain linker motif; other site
1124991003719	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1124991003720	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1124991003721	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1124991003722	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1124991003723	ATP-grasp domain; Region: ATP-grasp; pfam02222
1124991003724	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1124991003725	carbon starvation protein A; Provisional; Region: PRK15015
1124991003726	Carbon starvation protein CstA; Region: CstA; pfam02554
1124991003727	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1124991003728	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1124991003729	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1124991003730	P-loop, Walker A motif; other site
1124991003731	Base recognition motif; other site
1124991003732	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1124991003733	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1124991003734	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1124991003735	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1124991003736	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
1124991003737	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1124991003738	Tryptophanese operon leader peptide; Region: Tna_leader; cl15386
1124991003739	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
1124991003740	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1124991003741	substrate binding site [chemical binding]; other site
1124991003742	tetramer interface [polypeptide binding]; other site
1124991003743	catalytic residue [active]
1124991003744	tryptophan permease; Provisional; Region: PRK10483
1124991003745	aromatic amino acid transport protein; Region: araaP; TIGR00837
1124991003746	TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370
1124991003747	hypothetical protein; Provisional; Region: PRK02399
1124991003748	Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792
1124991003749	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991003750	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1124991003751	DNA-binding interface [nucleotide binding]; DNA binding site
1124991003752	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1124991003753	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1124991003754	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1124991003755	hypothetical protein; Provisional; Region: PRK08204
1124991003756	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1124991003757	active site
1124991003758	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
1124991003759	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991003760	Walker A/P-loop; other site
1124991003761	ATP binding site [chemical binding]; other site
1124991003762	Q-loop/lid; other site
1124991003763	ABC transporter signature motif; other site
1124991003764	Walker B; other site
1124991003765	D-loop; other site
1124991003766	H-loop/switch region; other site
1124991003767	TOBE domain; Region: TOBE_2; pfam08402
1124991003768	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1124991003769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991003770	dimer interface [polypeptide binding]; other site
1124991003771	conserved gate region; other site
1124991003772	putative PBP binding loops; other site
1124991003773	ABC-ATPase subunit interface; other site
1124991003774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991003775	dimer interface [polypeptide binding]; other site
1124991003776	conserved gate region; other site
1124991003777	putative PBP binding loops; other site
1124991003778	ABC-ATPase subunit interface; other site
1124991003779	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1124991003780	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1124991003781	regulatory protein UhpC; Provisional; Region: PRK11663
1124991003782	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991003783	putative substrate translocation pore; other site
1124991003784	MASE1; Region: MASE1; pfam05231
1124991003785	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
1124991003786	Histidine kinase; Region: HisKA_3; pfam07730
1124991003787	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991003788	ATP binding site [chemical binding]; other site
1124991003789	Mg2+ binding site [ion binding]; other site
1124991003790	G-X-G motif; other site
1124991003791	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1124991003792	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991003793	active site
1124991003794	phosphorylation site [posttranslational modification]
1124991003795	intermolecular recognition site; other site
1124991003796	dimerization interface [polypeptide binding]; other site
1124991003797	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991003798	DNA binding residues [nucleotide binding]
1124991003799	dimerization interface [polypeptide binding]; other site
1124991003800	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1124991003801	multicopper oxidase; Provisional; Region: PRK10965
1124991003802	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1124991003803	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1124991003804	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991003805	active site
1124991003806	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1124991003807	active site clefts [active]
1124991003808	zinc binding site [ion binding]; other site
1124991003809	dimer interface [polypeptide binding]; other site
1124991003810	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1124991003811	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1124991003812	Walker A/P-loop; other site
1124991003813	ATP binding site [chemical binding]; other site
1124991003814	Q-loop/lid; other site
1124991003815	ABC transporter signature motif; other site
1124991003816	Walker B; other site
1124991003817	D-loop; other site
1124991003818	H-loop/switch region; other site
1124991003819	inner membrane transport permease; Provisional; Region: PRK15066
1124991003820	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991003821	Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277
1124991003822	active site
1124991003823	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
1124991003824	Protease inhibitor Inh; Region: Inh; pfam02974
1124991003825	ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618
1124991003826	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991003827	Walker A/P-loop; other site
1124991003828	ATP binding site [chemical binding]; other site
1124991003829	Q-loop/lid; other site
1124991003830	ABC transporter signature motif; other site
1124991003831	Walker B; other site
1124991003832	D-loop; other site
1124991003833	H-loop/switch region; other site
1124991003834	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1124991003835	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991003836	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991003837	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1124991003838	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1124991003839	pantoate--beta-alanine ligase; Reviewed; Region: panC; PRK00380
1124991003840	active site
1124991003841	nucleotide binding site [chemical binding]; other site
1124991003842	HIGH motif; other site
1124991003843	KMSKS motif; other site
1124991003844	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1124991003845	catalytic center binding site [active]
1124991003846	ATP binding site [chemical binding]; other site
1124991003847	poly(A) polymerase; Region: pcnB; TIGR01942
1124991003848	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1124991003849	active site
1124991003850	NTP binding site [chemical binding]; other site
1124991003851	metal binding triad [ion binding]; metal-binding site
1124991003852	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1124991003853	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1124991003854	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1124991003855	active site
1124991003856	nucleotide binding site [chemical binding]; other site
1124991003857	HIGH motif; other site
1124991003858	KMSKS motif; other site
1124991003859	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1124991003860	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1124991003861	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1124991003862	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991003863	ATP binding site [chemical binding]; other site
1124991003864	putative Mg++ binding site [ion binding]; other site
1124991003865	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991003866	nucleotide binding region [chemical binding]; other site
1124991003867	ATP-binding site [chemical binding]; other site
1124991003868	Helicase associated domain (HA2); Region: HA2; pfam04408
1124991003869	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1124991003870	penicillin-binding protein 1B; Region: PBP_1b; TIGR02071
1124991003871	Transglycosylase; Region: Transgly; pfam00912
1124991003872	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1124991003873	Fic/DOC family; Region: Fic; pfam02661
1124991003874	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1124991003875	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1124991003876	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1124991003877	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1124991003878	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991003879	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991003880	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991003881	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1124991003882	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1124991003883	molybdopterin cofactor binding site; other site
1124991003884	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991003885	Helix-turn-helix domain; Region: HTH_18; pfam12833
1124991003886	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991003887	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1124991003888	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1124991003889	putative [Fe4-S4] binding site [ion binding]; other site
1124991003890	putative molybdopterin cofactor binding site [chemical binding]; other site
1124991003891	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1124991003892	putative molybdopterin cofactor binding site; other site
1124991003893	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1124991003894	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991003895	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1124991003896	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1124991003897	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1124991003898	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1124991003899	inhibitor-cofactor binding pocket; inhibition site
1124991003900	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991003901	catalytic residue [active]
1124991003902	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1124991003903	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991003904	FeS/SAM binding site; other site
1124991003905	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1124991003906	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1124991003907	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991003908	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1124991003909	molybdopterin cofactor binding site; other site
1124991003910	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1124991003911	molybdopterin cofactor binding site; other site
1124991003912	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1124991003913	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1124991003914	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
1124991003915	ADP-ribose binding site [chemical binding]; other site
1124991003916	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1124991003917	cobalamin binding residues [chemical binding]; other site
1124991003918	putative BtuC binding residues; other site
1124991003919	dimer interface [polypeptide binding]; other site
1124991003920	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1124991003921	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1124991003922	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1124991003923	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1124991003924	Zn2+ binding site [ion binding]; other site
1124991003925	Mg2+ binding site [ion binding]; other site
1124991003926	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1124991003927	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
1124991003928	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1124991003929	TRAM domain; Region: TRAM; pfam01938
1124991003930	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1124991003931	HD domain; Region: HD_4; pfam13328
1124991003932	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1124991003933	synthetase active site [active]
1124991003934	NTP binding site [chemical binding]; other site
1124991003935	metal binding site [ion binding]; metal-binding site
1124991003936	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1124991003937	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1124991003938	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1124991003939	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1124991003940	homodimer interface [polypeptide binding]; other site
1124991003941	metal binding site [ion binding]; metal-binding site
1124991003942	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1124991003943	homodimer interface [polypeptide binding]; other site
1124991003944	active site
1124991003945	putative chemical substrate binding site [chemical binding]; other site
1124991003946	metal binding site [ion binding]; metal-binding site
1124991003947	CTP synthetase; Validated; Region: pyrG; PRK05380
1124991003948	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1124991003949	Catalytic site [active]
1124991003950	active site
1124991003951	UTP binding site [chemical binding]; other site
1124991003952	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1124991003953	active site
1124991003954	putative oxyanion hole; other site
1124991003955	catalytic triad [active]
1124991003956	enolase; Provisional; Region: eno; PRK00077
1124991003957	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1124991003958	dimer interface [polypeptide binding]; other site
1124991003959	metal binding site [ion binding]; metal-binding site
1124991003960	substrate binding pocket [chemical binding]; other site
1124991003961	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1124991003962	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1124991003963	transmembrane helices; other site
1124991003964	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1124991003965	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1124991003966	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1124991003967	catalytic residue [active]
1124991003968	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1124991003969	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1124991003970	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
1124991003971	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991003972	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1124991003973	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1124991003974	RNA/DNA hybrid binding site [nucleotide binding]; other site
1124991003975	active site
1124991003976	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1124991003977	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1124991003978	active site
1124991003979	catalytic site [active]
1124991003980	substrate binding site [chemical binding]; other site
1124991003981	xanthine permease; Region: pbuX; TIGR03173
1124991003982	transketolase; Reviewed; Region: PRK12753
1124991003983	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1124991003984	TPP-binding site [chemical binding]; other site
1124991003985	dimer interface [polypeptide binding]; other site
1124991003986	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1124991003987	PYR/PP interface [polypeptide binding]; other site
1124991003988	dimer interface [polypeptide binding]; other site
1124991003989	TPP binding site [chemical binding]; other site
1124991003990	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1124991003991	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1124991003992	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1124991003993	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1124991003994	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1124991003995	Phosphoglycerate kinase; Region: PGK; pfam00162
1124991003996	substrate binding site [chemical binding]; other site
1124991003997	hinge regions; other site
1124991003998	ADP binding site [chemical binding]; other site
1124991003999	catalytic site [active]
1124991004000	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1124991004001	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1124991004002	active site
1124991004003	intersubunit interface [polypeptide binding]; other site
1124991004004	zinc binding site [ion binding]; other site
1124991004005	Na+ binding site [ion binding]; other site
1124991004006	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1124991004007	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
1124991004008	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991004009	active site
1124991004010	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
1124991004011	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1124991004012	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1124991004013	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1124991004014	putative metal binding site [ion binding]; other site
1124991004015	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1124991004016	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1124991004017	putative metal binding site [ion binding]; other site
1124991004018	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1124991004019	putative metal binding site [ion binding]; other site
1124991004020	tellurite resistance protein terB; Region: terB; cd07176
1124991004021	putative metal binding site [ion binding]; other site
1124991004022	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1124991004023	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1124991004024	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1124991004025	putative metal binding site [ion binding]; other site
1124991004026	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1124991004027	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1124991004028	putative metal binding site [ion binding]; other site
1124991004029	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1124991004030	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1124991004031	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1124991004032	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004033	putative substrate translocation pore; other site
1124991004034	POT family; Region: PTR2; pfam00854
1124991004035	Flavin Reductases; Region: FlaRed; cl00801
1124991004036	succinic semialdehyde dehydrogenase; Region: PLN02278
1124991004037	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1124991004038	tetramerization interface [polypeptide binding]; other site
1124991004039	NAD(P) binding site [chemical binding]; other site
1124991004040	catalytic residues [active]
1124991004041	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1124991004042	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1124991004043	BCCT family transporter; Region: BCCT; cl00569
1124991004044	Predicted membrane protein [Function unknown]; Region: COG2323
1124991004045	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1124991004046	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1124991004047	putative switch regulator; other site
1124991004048	non-specific DNA interactions [nucleotide binding]; other site
1124991004049	DNA binding site [nucleotide binding]
1124991004050	sequence specific DNA binding site [nucleotide binding]; other site
1124991004051	putative cAMP binding site [chemical binding]; other site
1124991004052	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1124991004053	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1124991004054	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991004055	active site
1124991004056	motif I; other site
1124991004057	motif II; other site
1124991004058	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991004059	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1124991004060	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1124991004061	phosphate binding site [ion binding]; other site
1124991004062	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1124991004063	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1124991004064	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1124991004065	active site
1124991004066	substrate binding site [chemical binding]; other site
1124991004067	FMN binding site [chemical binding]; other site
1124991004068	putative catalytic residues [active]
1124991004069	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1124991004070	L-lactate permease; Region: Lactate_perm; cl00701
1124991004071	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991004072	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991004073	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991004074	putative effector binding pocket; other site
1124991004075	dimerization interface [polypeptide binding]; other site
1124991004076	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1124991004077	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1124991004078	Lumazine-binding domain; Region: Lumazine_bd; pfam12870
1124991004079	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1124991004080	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991004081	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1124991004082	nucleoside transporter; Region: 2A0110; TIGR00889
1124991004083	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991004084	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991004085	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991004086	dimerization interface [polypeptide binding]; other site
1124991004087	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1124991004088	Family description; Region: VCBS; pfam13517
1124991004089	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
1124991004090	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
1124991004091	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
1124991004092	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1124991004093	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991004094	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991004095	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991004096	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991004097	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991004098	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991004099	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1124991004100	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
1124991004101	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
1124991004102	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1124991004103	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1124991004104	hypothetical protein; Provisional; Region: PRK09945
1124991004105	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1124991004106	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991004107	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1124991004108	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1124991004109	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1124991004110	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1124991004111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004112	dimer interface [polypeptide binding]; other site
1124991004113	conserved gate region; other site
1124991004114	putative PBP binding loops; other site
1124991004115	ABC-ATPase subunit interface; other site
1124991004116	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004117	dimer interface [polypeptide binding]; other site
1124991004118	conserved gate region; other site
1124991004119	putative PBP binding loops; other site
1124991004120	ABC-ATPase subunit interface; other site
1124991004121	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1124991004122	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1124991004123	Walker A/P-loop; other site
1124991004124	ATP binding site [chemical binding]; other site
1124991004125	Q-loop/lid; other site
1124991004126	ABC transporter signature motif; other site
1124991004127	Walker B; other site
1124991004128	D-loop; other site
1124991004129	H-loop/switch region; other site
1124991004130	Beta/Gamma crystallin; Region: Crystall; cl02528
1124991004131	Methyltransferase domain; Region: Methyltransf_12; pfam08242
1124991004132	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1124991004133	Class I aldolases; Region: Aldolase_Class_I; cl17187
1124991004134	catalytic residue [active]
1124991004135	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1124991004136	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1124991004137	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1124991004138	putative active site [active]
1124991004139	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1124991004140	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1124991004141	Na binding site [ion binding]; other site
1124991004142	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1124991004143	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1124991004144	nucleotide binding site [chemical binding]; other site
1124991004145	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1124991004146	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1124991004147	putative active site cavity [active]
1124991004148	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1124991004149	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1124991004150	Kelch motif; Region: Kelch_1; pfam01344
1124991004151	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1124991004152	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1124991004153	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1124991004154	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1124991004155	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1124991004156	catalytic residue [active]
1124991004157	oxidative damage protection protein; Provisional; Region: PRK05408
1124991004158	adenine DNA glycosylase; Provisional; Region: PRK10880
1124991004159	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1124991004160	minor groove reading motif; other site
1124991004161	helix-hairpin-helix signature motif; other site
1124991004162	substrate binding pocket [chemical binding]; other site
1124991004163	active site
1124991004164	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1124991004165	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1124991004166	DNA binding and oxoG recognition site [nucleotide binding]
1124991004167	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1124991004168	hypothetical protein; Provisional; Region: PRK11702
1124991004169	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1124991004170	glutaminase; Provisional; Region: PRK00971
1124991004171	hypothetical protein; Provisional; Region: PRK10626
1124991004172	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1124991004173	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1124991004174	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991004175	intersubunit interface [polypeptide binding]; other site
1124991004176	HemN family oxidoreductase; Provisional; Region: PRK05660
1124991004177	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991004178	FeS/SAM binding site; other site
1124991004179	HemN C-terminal domain; Region: HemN_C; pfam06969
1124991004180	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1124991004181	active site
1124991004182	dimerization interface [polypeptide binding]; other site
1124991004183	YGGT family; Region: YGGT; pfam02325
1124991004184	YGGT family; Region: YGGT; pfam02325
1124991004185	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1124991004186	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1124991004187	catalytic residue [active]
1124991004188	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1124991004189	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1124991004190	Walker A motif; other site
1124991004191	ATP binding site [chemical binding]; other site
1124991004192	Walker B motif; other site
1124991004193	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1124991004194	hypothetical protein; Validated; Region: PRK00228
1124991004195	glutathione synthetase; Provisional; Region: PRK05246
1124991004196	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1124991004197	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1124991004198	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1124991004199	RNA methyltransferase, RsmE family; Region: TIGR00046
1124991004200	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1124991004201	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1124991004202	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
1124991004203	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
1124991004204	catalytic residues [active]
1124991004205	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1124991004206	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991004207	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991004208	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991004209	putative effector binding pocket; other site
1124991004210	dimerization interface [polypeptide binding]; other site
1124991004211	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1124991004212	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991004213	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991004214	dimerization interface [polypeptide binding]; other site
1124991004215	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1124991004216	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1124991004217	active site
1124991004218	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1124991004219	substrate binding site [chemical binding]; other site
1124991004220	catalytic residues [active]
1124991004221	dimer interface [polypeptide binding]; other site
1124991004222	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1124991004223	phosphate binding site [ion binding]; other site
1124991004224	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1124991004225	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1124991004226	putative ligand binding residues [chemical binding]; other site
1124991004227	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1124991004228	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1124991004229	active site
1124991004230	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1124991004231	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1124991004232	dimer interface [polypeptide binding]; other site
1124991004233	active site
1124991004234	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1124991004235	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1124991004236	putative active site [active]
1124991004237	putative dimer interface [polypeptide binding]; other site
1124991004238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1124991004239	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
1124991004240	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1124991004241	E3 interaction surface; other site
1124991004242	lipoyl attachment site [posttranslational modification]; other site
1124991004243	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1124991004244	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
1124991004245	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1124991004246	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1124991004247	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1124991004248	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1124991004249	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1124991004250	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991004251	catalytic loop [active]
1124991004252	iron binding site [ion binding]; other site
1124991004253	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1124991004254	FAD binding pocket [chemical binding]; other site
1124991004255	FAD binding motif [chemical binding]; other site
1124991004256	phosphate binding motif [ion binding]; other site
1124991004257	beta-alpha-beta structure motif; other site
1124991004258	NAD binding pocket [chemical binding]; other site
1124991004259	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1124991004260	ApbE family; Region: ApbE; pfam02424
1124991004261	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
1124991004262	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1124991004263	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1124991004264	active site
1124991004265	catalytic site [active]
1124991004266	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1124991004267	active site
1124991004268	DNA polymerase IV; Validated; Region: PRK02406
1124991004269	DNA binding site [nucleotide binding]
1124991004270	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1124991004271	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1124991004272	metal binding site [ion binding]; metal-binding site
1124991004273	dimer interface [polypeptide binding]; other site
1124991004274	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991004275	active site
1124991004276	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1124991004277	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1124991004278	gamma-glutamyl kinase; Provisional; Region: PRK05429
1124991004279	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1124991004280	nucleotide binding site [chemical binding]; other site
1124991004281	homotetrameric interface [polypeptide binding]; other site
1124991004282	putative phosphate binding site [ion binding]; other site
1124991004283	putative allosteric binding site; other site
1124991004284	PUA domain; Region: PUA; pfam01472
1124991004285	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1124991004286	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1124991004287	putative catalytic cysteine [active]
1124991004288	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1124991004289	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1124991004290	ADP binding site [chemical binding]; other site
1124991004291	magnesium binding site [ion binding]; other site
1124991004292	putative shikimate binding site; other site
1124991004293	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1124991004294	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1124991004295	putative acyl-acceptor binding pocket; other site
1124991004296	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1124991004297	acyl-activating enzyme (AAE) consensus motif; other site
1124991004298	putative AMP binding site [chemical binding]; other site
1124991004299	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1124991004300	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004301	putative substrate translocation pore; other site
1124991004302	Competence-damaged protein; Region: CinA; cl00666
1124991004303	recombinase A; Provisional; Region: recA; PRK09354
1124991004304	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1124991004305	hexamer interface [polypeptide binding]; other site
1124991004306	Walker A motif; other site
1124991004307	ATP binding site [chemical binding]; other site
1124991004308	Walker B motif; other site
1124991004309	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1124991004310	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1124991004311	motif 1; other site
1124991004312	active site
1124991004313	motif 2; other site
1124991004314	motif 3; other site
1124991004315	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1124991004316	DHHA1 domain; Region: DHHA1; pfam02272
1124991004317	carbon storage regulator; Provisional; Region: PRK01712
1124991004318	glutamate--cysteine ligase; Provisional; Region: PRK02107
1124991004319	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1124991004320	hypothetical protein; Provisional; Region: PRK11573
1124991004321	Domain of unknown function DUF21; Region: DUF21; pfam01595
1124991004322	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1124991004323	Transporter associated domain; Region: CorC_HlyC; smart01091
1124991004324	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1124991004325	signal recognition particle protein; Provisional; Region: PRK10867
1124991004326	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1124991004327	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1124991004328	P loop; other site
1124991004329	GTP binding site [chemical binding]; other site
1124991004330	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1124991004331	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1124991004332	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1124991004333	RimM N-terminal domain; Region: RimM; pfam01782
1124991004334	PRC-barrel domain; Region: PRC; pfam05239
1124991004335	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1124991004336	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1124991004337	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1124991004338	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1124991004339	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1124991004340	Chorismate mutase type II; Region: CM_2; cl00693
1124991004341	prephenate dehydrogenase; Validated; Region: PRK08507
1124991004342	poxB regulator PoxA; Provisional; Region: PRK09350
1124991004343	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1124991004344	motif 1; other site
1124991004345	dimer interface [polypeptide binding]; other site
1124991004346	active site
1124991004347	motif 2; other site
1124991004348	motif 3; other site
1124991004349	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1124991004350	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1124991004351	Prephenate dehydratase; Region: PDT; pfam00800
1124991004352	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1124991004353	putative L-Phe binding site [chemical binding]; other site
1124991004354	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1124991004355	30S subunit binding site; other site
1124991004356	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1124991004357	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1124991004358	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991004359	RNA binding surface [nucleotide binding]; other site
1124991004360	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1124991004361	active site
1124991004362	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
1124991004363	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1124991004364	protein disaggregation chaperone; Provisional; Region: PRK10865
1124991004365	Clp amino terminal domain; Region: Clp_N; pfam02861
1124991004366	Clp amino terminal domain; Region: Clp_N; pfam02861
1124991004367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991004368	Walker A motif; other site
1124991004369	ATP binding site [chemical binding]; other site
1124991004370	Walker B motif; other site
1124991004371	arginine finger; other site
1124991004372	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991004373	Walker A motif; other site
1124991004374	ATP binding site [chemical binding]; other site
1124991004375	Walker B motif; other site
1124991004376	arginine finger; other site
1124991004377	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1124991004378	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991004379	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1124991004380	Autotransporter beta-domain; Region: Autotransporter; smart00869
1124991004381	lipoprotein; Provisional; Region: PRK10759
1124991004382	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1124991004383	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1124991004384	domain interface [polypeptide binding]; other site
1124991004385	putative active site [active]
1124991004386	catalytic site [active]
1124991004387	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1124991004388	domain interface [polypeptide binding]; other site
1124991004389	putative active site [active]
1124991004390	catalytic site [active]
1124991004391	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1124991004392	CoA binding domain; Region: CoA_binding_2; pfam13380
1124991004393	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1124991004394	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1124991004395	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1124991004396	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991004397	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1124991004398	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1124991004399	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1124991004400	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1124991004401	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1124991004402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004403	putative substrate translocation pore; other site
1124991004404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004405	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1124991004406	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991004407	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991004408	transcriptional repressor MprA; Provisional; Region: PRK10870
1124991004409	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1124991004410	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1124991004411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004412	putative substrate translocation pore; other site
1124991004413	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1124991004414	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1124991004415	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1124991004416	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004417	dimer interface [polypeptide binding]; other site
1124991004418	conserved gate region; other site
1124991004419	putative PBP binding loops; other site
1124991004420	ABC-ATPase subunit interface; other site
1124991004421	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1124991004422	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1124991004423	Walker A/P-loop; other site
1124991004424	ATP binding site [chemical binding]; other site
1124991004425	Q-loop/lid; other site
1124991004426	ABC transporter signature motif; other site
1124991004427	Walker B; other site
1124991004428	D-loop; other site
1124991004429	H-loop/switch region; other site
1124991004430	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1124991004431	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1124991004432	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1124991004433	dimer interface [polypeptide binding]; other site
1124991004434	putative radical transfer pathway; other site
1124991004435	diiron center [ion binding]; other site
1124991004436	tyrosyl radical; other site
1124991004437	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1124991004438	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1124991004439	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1124991004440	active site
1124991004441	dimer interface [polypeptide binding]; other site
1124991004442	catalytic residues [active]
1124991004443	effector binding site; other site
1124991004444	R2 peptide binding site; other site
1124991004445	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1124991004446	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1124991004447	catalytic residues [active]
1124991004448	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1124991004449	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1124991004450	active site residue [active]
1124991004451	AAA domain; Region: AAA_17; pfam13207
1124991004452	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1124991004453	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1124991004454	DNA binding site [nucleotide binding]
1124991004455	active site
1124991004456	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991004457	DNA-binding site [nucleotide binding]; DNA binding site
1124991004458	RNA-binding motif; other site
1124991004459	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1124991004460	EamA-like transporter family; Region: EamA; pfam00892
1124991004461	lipoyl synthase; Provisional; Region: PRK05481
1124991004462	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991004463	FeS/SAM binding site; other site
1124991004464	lipoate-protein ligase B; Provisional; Region: PRK14342
1124991004465	hypothetical protein; Provisional; Region: PRK04998
1124991004466	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1124991004467	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1124991004468	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1124991004469	rare lipoprotein A; Provisional; Region: PRK10672
1124991004470	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1124991004471	Sporulation related domain; Region: SPOR; pfam05036
1124991004472	cell wall shape-determining protein; Provisional; Region: PRK10794
1124991004473	penicillin-binding protein 2; Provisional; Region: PRK10795
1124991004474	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1124991004475	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1124991004476	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1124991004477	ribosome-associated protein; Provisional; Region: PRK11538
1124991004478	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1124991004479	Protein of unknown function (DUF1722); Region: DUF1722; pfam08349
1124991004480	Predicted transcriptional regulators [Transcription]; Region: COG1733
1124991004481	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1124991004482	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1124991004483	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1124991004484	NAD(P) binding site [chemical binding]; other site
1124991004485	active site
1124991004486	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1124991004487	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1124991004488	active site
1124991004489	(T/H)XGH motif; other site
1124991004490	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1124991004491	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1124991004492	Lipopolysaccharide-assembly; Region: LptE; cl01125
1124991004493	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1124991004494	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1124991004495	HIGH motif; other site
1124991004496	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1124991004497	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1124991004498	active site
1124991004499	KMSKS motif; other site
1124991004500	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1124991004501	tRNA binding surface [nucleotide binding]; other site
1124991004502	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1124991004503	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1124991004504	Walker A/P-loop; other site
1124991004505	ATP binding site [chemical binding]; other site
1124991004506	Q-loop/lid; other site
1124991004507	ABC transporter signature motif; other site
1124991004508	Walker B; other site
1124991004509	D-loop; other site
1124991004510	H-loop/switch region; other site
1124991004511	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004512	dimer interface [polypeptide binding]; other site
1124991004513	conserved gate region; other site
1124991004514	putative PBP binding loops; other site
1124991004515	ABC-ATPase subunit interface; other site
1124991004516	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1124991004517	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004518	dimer interface [polypeptide binding]; other site
1124991004519	conserved gate region; other site
1124991004520	putative PBP binding loops; other site
1124991004521	ABC-ATPase subunit interface; other site
1124991004522	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1124991004523	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991004524	substrate binding pocket [chemical binding]; other site
1124991004525	membrane-bound complex binding site; other site
1124991004526	hinge residues; other site
1124991004527	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1124991004528	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1124991004529	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1124991004530	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1124991004531	DsbD alpha interface [polypeptide binding]; other site
1124991004532	catalytic residues [active]
1124991004533	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1124991004534	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1124991004535	catalytic residues [active]
1124991004536	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1124991004537	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1124991004538	catalytic residues [active]
1124991004539	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1124991004540	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1124991004541	putative active site [active]
1124991004542	catalytic triad [active]
1124991004543	putative dimer interface [polypeptide binding]; other site
1124991004544	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1124991004545	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1124991004546	Transporter associated domain; Region: CorC_HlyC; smart01091
1124991004547	metal-binding heat shock protein; Provisional; Region: PRK00016
1124991004548	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1124991004549	PhoH-like protein; Region: PhoH; pfam02562
1124991004550	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1124991004551	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1124991004552	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991004553	FeS/SAM binding site; other site
1124991004554	TRAM domain; Region: TRAM; pfam01938
1124991004555	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1124991004556	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1124991004557	MarR family; Region: MarR; pfam01047
1124991004558	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1124991004559	ROK family; Region: ROK; pfam00480
1124991004560	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1124991004561	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1124991004562	active site
1124991004563	dimer interface [polypeptide binding]; other site
1124991004564	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1124991004565	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1124991004566	active site
1124991004567	trimer interface [polypeptide binding]; other site
1124991004568	allosteric site; other site
1124991004569	active site lid [active]
1124991004570	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1124991004571	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1124991004572	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1124991004573	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1124991004574	active site turn [active]
1124991004575	phosphorylation site [posttranslational modification]
1124991004576	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1124991004577	HPr interaction site; other site
1124991004578	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1124991004579	active site
1124991004580	phosphorylation site [posttranslational modification]
1124991004581	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1124991004582	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1124991004583	active site
1124991004584	HIGH motif; other site
1124991004585	nucleotide binding site [chemical binding]; other site
1124991004586	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1124991004587	KMSKS motif; other site
1124991004588	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1124991004589	ferric uptake regulator; Provisional; Region: fur; PRK09462
1124991004590	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1124991004591	metal binding site 2 [ion binding]; metal-binding site
1124991004592	putative DNA binding helix; other site
1124991004593	metal binding site 1 [ion binding]; metal-binding site
1124991004594	dimer interface [polypeptide binding]; other site
1124991004595	structural Zn2+ binding site [ion binding]; other site
1124991004596	flavodoxin FldA; Validated; Region: PRK09267
1124991004597	LexA regulated protein; Provisional; Region: PRK11675
1124991004598	acyl-CoA esterase; Provisional; Region: PRK10673
1124991004599	PGAP1-like protein; Region: PGAP1; pfam07819
1124991004600	replication initiation regulator SeqA; Provisional; Region: PRK11187
1124991004601	phosphoglucomutase; Validated; Region: PRK07564
1124991004602	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1124991004603	active site
1124991004604	substrate binding site [chemical binding]; other site
1124991004605	metal binding site [ion binding]; metal-binding site
1124991004606	Predicted membrane protein [Function unknown]; Region: COG2510
1124991004607	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1124991004608	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1124991004609	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1124991004610	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1124991004611	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004612	putative substrate translocation pore; other site
1124991004613	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1124991004614	Helix-turn-helix domain; Region: HTH_18; pfam12833
1124991004615	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991004616	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1124991004617	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1124991004618	dimer interface [polypeptide binding]; other site
1124991004619	active site
1124991004620	citrylCoA binding site [chemical binding]; other site
1124991004621	NADH binding [chemical binding]; other site
1124991004622	cationic pore residues; other site
1124991004623	oxalacetate/citrate binding site [chemical binding]; other site
1124991004624	coenzyme A binding site [chemical binding]; other site
1124991004625	catalytic triad [active]
1124991004626	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1124991004627	Iron-sulfur protein interface; other site
1124991004628	proximal quinone binding site [chemical binding]; other site
1124991004629	SdhD (CybS) interface [polypeptide binding]; other site
1124991004630	proximal heme binding site [chemical binding]; other site
1124991004631	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1124991004632	SdhC subunit interface [polypeptide binding]; other site
1124991004633	proximal heme binding site [chemical binding]; other site
1124991004634	cardiolipin binding site; other site
1124991004635	Iron-sulfur protein interface; other site
1124991004636	proximal quinone binding site [chemical binding]; other site
1124991004637	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1124991004638	L-aspartate oxidase; Provisional; Region: PRK06175
1124991004639	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1124991004640	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1124991004641	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1124991004642	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1124991004643	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1124991004644	TPP-binding site [chemical binding]; other site
1124991004645	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1124991004646	dimer interface [polypeptide binding]; other site
1124991004647	PYR/PP interface [polypeptide binding]; other site
1124991004648	TPP binding site [chemical binding]; other site
1124991004649	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1124991004650	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1124991004651	E3 interaction surface; other site
1124991004652	lipoyl attachment site [posttranslational modification]; other site
1124991004653	e3 binding domain; Region: E3_binding; pfam02817
1124991004654	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1124991004655	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1124991004656	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1124991004657	CoA-ligase; Region: Ligase_CoA; pfam00549
1124991004658	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1124991004659	CoA binding domain; Region: CoA_binding; smart00881
1124991004660	CoA-ligase; Region: Ligase_CoA; pfam00549
1124991004661	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1124991004662	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1124991004663	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1124991004664	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1124991004665	Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173
1124991004666	hypothetical protein; Provisional; Region: PRK10588
1124991004667	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991004668	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991004669	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991004670	putative effector binding pocket; other site
1124991004671	dimerization interface [polypeptide binding]; other site
1124991004672	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1124991004673	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004674	putative substrate translocation pore; other site
1124991004675	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1124991004676	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1124991004677	active site
1124991004678	colicin uptake protein TolQ; Provisional; Region: PRK10801
1124991004679	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1124991004680	colicin uptake protein TolR; Provisional; Region: PRK11024
1124991004681	TolA C-terminal; Region: TolA; pfam06519
1124991004682	translocation protein TolB; Provisional; Region: tolB; PRK03629
1124991004683	TolB amino-terminal domain; Region: TolB_N; pfam04052
1124991004684	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1124991004685	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1124991004686	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1124991004687	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1124991004688	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1124991004689	ligand binding site [chemical binding]; other site
1124991004690	tol-pal system protein YbgF; Provisional; Region: PRK10803
1124991004691	SlyX; Region: SlyX; cl01090
1124991004692	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1124991004693	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
1124991004694	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1124991004695	Protein of unknown function (DUF808); Region: DUF808; pfam05661
1124991004696	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1124991004697	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1124991004698	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1124991004699	catalytic core [active]
1124991004700	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1124991004701	CAAX protease self-immunity; Region: Abi; pfam02517
1124991004702	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1124991004703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1124991004704	Walker A/P-loop; other site
1124991004705	ATP binding site [chemical binding]; other site
1124991004706	Q-loop/lid; other site
1124991004707	ABC transporter signature motif; other site
1124991004708	Walker B; other site
1124991004709	D-loop; other site
1124991004710	H-loop/switch region; other site
1124991004711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991004712	Walker A/P-loop; other site
1124991004713	ATP binding site [chemical binding]; other site
1124991004714	Q-loop/lid; other site
1124991004715	ABC transporter signature motif; other site
1124991004716	Walker B; other site
1124991004717	D-loop; other site
1124991004718	H-loop/switch region; other site
1124991004719	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1124991004720	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1124991004721	active site
1124991004722	metal binding site [ion binding]; metal-binding site
1124991004723	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1124991004724	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1124991004725	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1124991004726	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1124991004727	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1124991004728	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1124991004729	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1124991004730	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1124991004731	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1124991004732	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991004733	dimer interface [polypeptide binding]; other site
1124991004734	conserved gate region; other site
1124991004735	putative PBP binding loops; other site
1124991004736	ABC-ATPase subunit interface; other site
1124991004737	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1124991004738	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991004739	Walker A/P-loop; other site
1124991004740	ATP binding site [chemical binding]; other site
1124991004741	Q-loop/lid; other site
1124991004742	ABC transporter signature motif; other site
1124991004743	Walker B; other site
1124991004744	D-loop; other site
1124991004745	H-loop/switch region; other site
1124991004746	TOBE domain; Region: TOBE; cl01440
1124991004747	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1124991004748	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991004749	active site
1124991004750	motif I; other site
1124991004751	motif II; other site
1124991004752	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991004753	6-phosphogluconolactonase; Provisional; Region: PRK11028
1124991004754	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1124991004755	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1124991004756	inhibitor-cofactor binding pocket; inhibition site
1124991004757	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991004758	catalytic residue [active]
1124991004759	biotin synthase; Provisional; Region: PRK15108
1124991004760	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991004761	FeS/SAM binding site; other site
1124991004762	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1124991004763	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1124991004764	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1124991004765	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991004766	catalytic residue [active]
1124991004767	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1124991004768	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991004769	S-adenosylmethionine binding site [chemical binding]; other site
1124991004770	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1124991004771	AAA domain; Region: AAA_26; pfam13500
1124991004772	excinuclease ABC subunit B; Provisional; Region: PRK05298
1124991004773	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991004774	ATP binding site [chemical binding]; other site
1124991004775	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991004776	nucleotide binding region [chemical binding]; other site
1124991004777	ATP-binding site [chemical binding]; other site
1124991004778	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1124991004779	UvrB/uvrC motif; Region: UVR; pfam02151
1124991004780	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1124991004781	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1124991004782	putative substrate binding pocket [chemical binding]; other site
1124991004783	dimer interface [polypeptide binding]; other site
1124991004784	phosphate binding site [ion binding]; other site
1124991004785	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1124991004786	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991004787	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1124991004788	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991004789	FeS/SAM binding site; other site
1124991004790	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1124991004791	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1124991004792	trimer interface [polypeptide binding]; other site
1124991004793	dimer interface [polypeptide binding]; other site
1124991004794	putative active site [active]
1124991004795	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1124991004796	MoaE interaction surface [polypeptide binding]; other site
1124991004797	MoeB interaction surface [polypeptide binding]; other site
1124991004798	thiocarboxylated glycine; other site
1124991004799	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1124991004800	MoaE homodimer interface [polypeptide binding]; other site
1124991004801	MoaD interaction [polypeptide binding]; other site
1124991004802	active site residues [active]
1124991004803	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1124991004804	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1124991004805	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991004806	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1124991004807	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991004808	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1124991004809	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1124991004810	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1124991004811	Walker A/P-loop; other site
1124991004812	ATP binding site [chemical binding]; other site
1124991004813	Q-loop/lid; other site
1124991004814	ABC transporter signature motif; other site
1124991004815	Walker B; other site
1124991004816	D-loop; other site
1124991004817	H-loop/switch region; other site
1124991004818	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1124991004819	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1124991004820	Walker A/P-loop; other site
1124991004821	ATP binding site [chemical binding]; other site
1124991004822	Q-loop/lid; other site
1124991004823	ABC transporter signature motif; other site
1124991004824	Walker B; other site
1124991004825	D-loop; other site
1124991004826	H-loop/switch region; other site
1124991004827	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1124991004828	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991004829	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991004830	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1124991004831	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991004832	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1124991004833	helicase 45; Provisional; Region: PTZ00424
1124991004834	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1124991004835	ATP binding site [chemical binding]; other site
1124991004836	Mg++ binding site [ion binding]; other site
1124991004837	motif III; other site
1124991004838	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991004839	nucleotide binding region [chemical binding]; other site
1124991004840	ATP-binding site [chemical binding]; other site
1124991004841	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1124991004842	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1124991004843	FMN binding site [chemical binding]; other site
1124991004844	active site
1124991004845	catalytic residues [active]
1124991004846	substrate binding site [chemical binding]; other site
1124991004847	hypothetical protein; Provisional; Region: PRK10457
1124991004848	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1124991004849	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1124991004850	active site residue [active]
1124991004851	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1124991004852	active site residue [active]
1124991004853	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1124991004854	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1124991004855	DEAD_2; Region: DEAD_2; pfam06733
1124991004856	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1124991004857	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1124991004858	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991004859	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991004860	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1124991004861	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1124991004862	dimerization interface [polypeptide binding]; other site
1124991004863	DPS ferroxidase diiron center [ion binding]; other site
1124991004864	ion pore; other site
1124991004865	threonine and homoserine efflux system; Provisional; Region: PRK10532
1124991004866	EamA-like transporter family; Region: EamA; pfam00892
1124991004867	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
1124991004868	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1124991004869	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991004870	Coenzyme A binding pocket [chemical binding]; other site
1124991004871	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1124991004872	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1124991004873	active site
1124991004874	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1124991004875	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1124991004876	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1124991004877	Na binding site [ion binding]; other site
1124991004878	putative substrate binding site [chemical binding]; other site
1124991004879	cytosine deaminase; Provisional; Region: PRK09230
1124991004880	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1124991004881	active site
1124991004882	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1124991004883	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1124991004884	ATP binding site [chemical binding]; other site
1124991004885	substrate interface [chemical binding]; other site
1124991004886	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1124991004887	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1124991004888	dimer interface [polypeptide binding]; other site
1124991004889	putative functional site; other site
1124991004890	putative MPT binding site; other site
1124991004891	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991004892	putative substrate translocation pore; other site
1124991004893	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1124991004894	active site
1124991004895	Predicted membrane protein [Function unknown]; Region: COG2311
1124991004896	Protein of unknown function (DUF418); Region: DUF418; cl12135
1124991004897	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1124991004898	putative active site [active]
1124991004899	malate dehydrogenase; Provisional; Region: PRK13529
1124991004900	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1124991004901	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1124991004902	NAD(P) binding site [chemical binding]; other site
1124991004903	cytidine deaminase; Provisional; Region: PRK09027
1124991004904	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1124991004905	active site
1124991004906	catalytic motif [active]
1124991004907	Zn binding site [ion binding]; other site
1124991004908	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1124991004909	active site
1124991004910	catalytic motif [active]
1124991004911	Zn binding site [ion binding]; other site
1124991004912	hypothetical protein; Provisional; Region: PRK10711
1124991004913	hypothetical protein; Provisional; Region: PRK01821
1124991004914	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1124991004915	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1124991004916	active site
1124991004917	HIGH motif; other site
1124991004918	KMSKS motif; other site
1124991004919	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1124991004920	tRNA binding surface [nucleotide binding]; other site
1124991004921	anticodon binding site; other site
1124991004922	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1124991004923	dimer interface [polypeptide binding]; other site
1124991004924	putative tRNA-binding site [nucleotide binding]; other site
1124991004925	antiporter inner membrane protein; Provisional; Region: PRK11670
1124991004926	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1124991004927	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1124991004928	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1124991004929	ATP-binding site [chemical binding]; other site
1124991004930	Sugar specificity; other site
1124991004931	Pyrimidine base specificity; other site
1124991004932	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1124991004933	trimer interface [polypeptide binding]; other site
1124991004934	active site
1124991004935	putative assembly protein; Provisional; Region: PRK10833
1124991004936	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1124991004937	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1124991004938	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1124991004939	Lumazine binding domain; Region: Lum_binding; pfam00677
1124991004940	Rhomboid family; Region: Rhomboid; pfam01694
1124991004941	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1124991004942	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1124991004943	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1124991004944	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1124991004945	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
1124991004946	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1124991004947	Transporter associated domain; Region: CorC_HlyC; smart01091
1124991004948	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1124991004949	Catalase-like heme-binding proteins and protein domains; Region: catalase_like; cl09506
1124991004950	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1124991004951	putative deacylase active site [active]
1124991004952	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1124991004953	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1124991004954	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1124991004955	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1124991004956	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1124991004957	substrate binding site [chemical binding]; other site
1124991004958	glutamase interaction surface [polypeptide binding]; other site
1124991004959	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1124991004960	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1124991004961	catalytic residues [active]
1124991004962	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1124991004963	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1124991004964	putative active site [active]
1124991004965	oxyanion strand; other site
1124991004966	catalytic triad [active]
1124991004967	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1124991004968	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991004969	active site
1124991004970	motif I; other site
1124991004971	motif II; other site
1124991004972	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1124991004973	putative active site pocket [active]
1124991004974	4-fold oligomerization interface [polypeptide binding]; other site
1124991004975	metal binding residues [ion binding]; metal-binding site
1124991004976	3-fold/trimer interface [polypeptide binding]; other site
1124991004977	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1124991004978	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991004979	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991004980	homodimer interface [polypeptide binding]; other site
1124991004981	catalytic residue [active]
1124991004982	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1124991004983	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1124991004984	NAD binding site [chemical binding]; other site
1124991004985	dimerization interface [polypeptide binding]; other site
1124991004986	product binding site; other site
1124991004987	substrate binding site [chemical binding]; other site
1124991004988	zinc binding site [ion binding]; other site
1124991004989	catalytic residues [active]
1124991004990	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1124991004991	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1124991004992	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1124991004993	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1124991004994	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1124991004995	putative NAD(P) binding site [chemical binding]; other site
1124991004996	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1124991004997	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1124991004998	putative C-terminal domain interface [polypeptide binding]; other site
1124991004999	putative GSH binding site (G-site) [chemical binding]; other site
1124991005000	putative dimer interface [polypeptide binding]; other site
1124991005001	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1124991005002	putative N-terminal domain interface [polypeptide binding]; other site
1124991005003	putative dimer interface [polypeptide binding]; other site
1124991005004	putative substrate binding pocket (H-site) [chemical binding]; other site
1124991005005	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1124991005006	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1124991005007	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1124991005008	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991005009	LemA family; Region: LemA; cl00742
1124991005010	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1124991005011	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1124991005012	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1124991005013	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991005014	serine transporter; Region: stp; TIGR00814
1124991005015	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991005016	serine transporter; Region: stp; TIGR00814
1124991005017	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1124991005018	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1124991005019	active site
1124991005020	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1124991005021	GSH binding site [chemical binding]; other site
1124991005022	catalytic residues [active]
1124991005023	hypothetical protein; Provisional; Region: PRK10591
1124991005024	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1124991005025	23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522
1124991005026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991005027	S-adenosylmethionine binding site [chemical binding]; other site
1124991005028	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991005029	dimer interface [polypeptide binding]; other site
1124991005030	conserved gate region; other site
1124991005031	putative PBP binding loops; other site
1124991005032	ABC-ATPase subunit interface; other site
1124991005033	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1124991005034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991005035	dimer interface [polypeptide binding]; other site
1124991005036	conserved gate region; other site
1124991005037	putative PBP binding loops; other site
1124991005038	ABC-ATPase subunit interface; other site
1124991005039	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1124991005040	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991005041	substrate binding pocket [chemical binding]; other site
1124991005042	membrane-bound complex binding site; other site
1124991005043	hinge residues; other site
1124991005044	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1124991005045	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1124991005046	Walker A/P-loop; other site
1124991005047	ATP binding site [chemical binding]; other site
1124991005048	Q-loop/lid; other site
1124991005049	ABC transporter signature motif; other site
1124991005050	Walker B; other site
1124991005051	D-loop; other site
1124991005052	H-loop/switch region; other site
1124991005053	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1124991005054	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1124991005055	NAD(P) binding site [chemical binding]; other site
1124991005056	active site
1124991005057	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1124991005058	Predicted membrane protein [Function unknown]; Region: COG2431
1124991005059	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1124991005060	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1124991005061	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1124991005062	putative active site [active]
1124991005063	putative metal-binding site [ion binding]; other site
1124991005064	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1124991005065	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991005066	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991005067	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1124991005068	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1124991005069	Walker A/P-loop; other site
1124991005070	ATP binding site [chemical binding]; other site
1124991005071	Q-loop/lid; other site
1124991005072	ABC transporter signature motif; other site
1124991005073	Walker B; other site
1124991005074	D-loop; other site
1124991005075	H-loop/switch region; other site
1124991005076	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1124991005077	FtsX-like permease family; Region: FtsX; pfam02687
1124991005078	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991005079	DNA-binding site [nucleotide binding]; DNA binding site
1124991005080	RNA-binding motif; other site
1124991005081	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1124991005082	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1124991005083	Clp amino terminal domain; Region: Clp_N; pfam02861
1124991005084	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991005085	Walker A motif; other site
1124991005086	ATP binding site [chemical binding]; other site
1124991005087	Walker B motif; other site
1124991005088	arginine finger; other site
1124991005089	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991005090	Walker A motif; other site
1124991005091	ATP binding site [chemical binding]; other site
1124991005092	Walker B motif; other site
1124991005093	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1124991005094	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1124991005095	rRNA binding site [nucleotide binding]; other site
1124991005096	predicted 30S ribosome binding site; other site
1124991005097	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1124991005098	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1124991005099	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991005100	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991005101	Walker A/P-loop; other site
1124991005102	ATP binding site [chemical binding]; other site
1124991005103	Q-loop/lid; other site
1124991005104	ABC transporter signature motif; other site
1124991005105	Walker B; other site
1124991005106	D-loop; other site
1124991005107	H-loop/switch region; other site
1124991005108	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1124991005109	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991005110	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991005111	Walker A/P-loop; other site
1124991005112	ATP binding site [chemical binding]; other site
1124991005113	Q-loop/lid; other site
1124991005114	ABC transporter signature motif; other site
1124991005115	Walker B; other site
1124991005116	D-loop; other site
1124991005117	H-loop/switch region; other site
1124991005118	thioredoxin reductase; Provisional; Region: PRK10262
1124991005119	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991005120	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991005121	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1124991005122	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991005123	putative DNA binding site [nucleotide binding]; other site
1124991005124	putative Zn2+ binding site [ion binding]; other site
1124991005125	AsnC family; Region: AsnC_trans_reg; pfam01037
1124991005126	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1124991005127	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1124991005128	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1124991005129	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1124991005130	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1124991005131	recombination factor protein RarA; Reviewed; Region: PRK13342
1124991005132	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991005133	Walker A motif; other site
1124991005134	ATP binding site [chemical binding]; other site
1124991005135	Walker B motif; other site
1124991005136	arginine finger; other site
1124991005137	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1124991005138	seryl-tRNA synthetase; Provisional; Region: PRK05431
1124991005139	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1124991005140	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1124991005141	dimer interface [polypeptide binding]; other site
1124991005142	active site
1124991005143	motif 1; other site
1124991005144	motif 2; other site
1124991005145	motif 3; other site
1124991005146	Anthrax toxin LF subunit; Region: Anthrax_toxA; pfam03497
1124991005147	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1124991005148	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991005149	FeS/SAM binding site; other site
1124991005150	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1124991005151	Pyruvate formate lyase 1; Region: PFL1; cd01678
1124991005152	coenzyme A binding site [chemical binding]; other site
1124991005153	active site
1124991005154	catalytic residues [active]
1124991005155	glycine loop; other site
1124991005156	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1124991005157	uncharacterized domain; Region: TIGR00702
1124991005158	YcaO-like family; Region: YcaO; pfam02624
1124991005159	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1124991005160	homodimer interface [polypeptide binding]; other site
1124991005161	substrate-cofactor binding pocket; other site
1124991005162	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991005163	catalytic residue [active]
1124991005164	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1124991005165	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1124991005166	hinge; other site
1124991005167	active site
1124991005168	cytidylate kinase; Provisional; Region: cmk; PRK00023
1124991005169	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1124991005170	CMP-binding site; other site
1124991005171	The sites determining sugar specificity; other site
1124991005172	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1124991005173	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1124991005174	RNA binding site [nucleotide binding]; other site
1124991005175	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1124991005176	RNA binding site [nucleotide binding]; other site
1124991005177	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1124991005178	RNA binding site [nucleotide binding]; other site
1124991005179	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1124991005180	RNA binding site [nucleotide binding]; other site
1124991005181	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1124991005182	RNA binding site [nucleotide binding]; other site
1124991005183	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1124991005184	RNA binding site [nucleotide binding]; other site
1124991005185	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1124991005186	IHF dimer interface [polypeptide binding]; other site
1124991005187	IHF - DNA interface [nucleotide binding]; other site
1124991005188	ComEC family competence protein; Provisional; Region: PRK11539
1124991005189	Competence protein; Region: Competence; pfam03772
1124991005190	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1124991005191	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1124991005192	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991005193	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1124991005194	Walker A/P-loop; other site
1124991005195	ATP binding site [chemical binding]; other site
1124991005196	Q-loop/lid; other site
1124991005197	ABC transporter signature motif; other site
1124991005198	Walker B; other site
1124991005199	D-loop; other site
1124991005200	H-loop/switch region; other site
1124991005201	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1124991005202	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1124991005203	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991005204	DNA-binding site [nucleotide binding]; DNA binding site
1124991005205	RNA-binding motif; other site
1124991005206	Uncharacterized conserved protein [Function unknown]; Region: COG2835
1124991005207	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1124991005208	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1124991005209	Ligand binding site; other site
1124991005210	oligomer interface; other site
1124991005211	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1124991005212	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1124991005213	putative active site [active]
1124991005214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991005215	S-adenosylmethionine binding site [chemical binding]; other site
1124991005216	condesin subunit F; Provisional; Region: PRK05260
1124991005217	condesin subunit E; Provisional; Region: PRK05256
1124991005218	cell division protein MukB; Provisional; Region: mukB; PRK04863
1124991005219	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1124991005220	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1124991005221	Isochorismatase family; Region: Isochorismatase; pfam00857
1124991005222	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1124991005223	catalytic triad [active]
1124991005224	dimer interface [polypeptide binding]; other site
1124991005225	conserved cis-peptide bond; other site
1124991005226	acid phosphatase/phosphotransferase; Provisional; Region: aphA; PRK11009
1124991005227	murein L,D-transpeptidase; Provisional; Region: PRK10594
1124991005228	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1124991005229	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1124991005230	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1124991005231	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1124991005232	Peptidase M15; Region: Peptidase_M15_3; cl01194
1124991005233	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1124991005234	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1124991005235	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991005236	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991005237	homodimer interface [polypeptide binding]; other site
1124991005238	catalytic residue [active]
1124991005239	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1124991005240	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1124991005241	trimer interface [polypeptide binding]; other site
1124991005242	eyelet of channel; other site
1124991005243	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1124991005244	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1124991005245	putative dimer interface [polypeptide binding]; other site
1124991005246	putative anticodon binding site; other site
1124991005247	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1124991005248	homodimer interface [polypeptide binding]; other site
1124991005249	motif 1; other site
1124991005250	motif 2; other site
1124991005251	active site
1124991005252	motif 3; other site
1124991005253	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1124991005254	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1124991005255	active site
1124991005256	aminopeptidase N; Provisional; Region: pepN; PRK14015
1124991005257	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1124991005258	active site
1124991005259	Zn binding site [ion binding]; other site
1124991005260	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1124991005261	Repair protein; Region: Repair_PSII; pfam04536
1124991005262	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1124991005263	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1124991005264	quinone interaction residues [chemical binding]; other site
1124991005265	active site
1124991005266	catalytic residues [active]
1124991005267	FMN binding site [chemical binding]; other site
1124991005268	substrate binding site [chemical binding]; other site
1124991005269	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1124991005270	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1124991005271	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1124991005272	MOSC domain; Region: MOSC; pfam03473
1124991005273	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991005274	catalytic loop [active]
1124991005275	iron binding site [ion binding]; other site
1124991005276	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1124991005277	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1124991005278	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1124991005279	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991005280	S-adenosylmethionine binding site [chemical binding]; other site
1124991005281	ABC transporter ATPase component; Reviewed; Region: PRK11147
1124991005282	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991005283	Walker A/P-loop; other site
1124991005284	ATP binding site [chemical binding]; other site
1124991005285	Q-loop/lid; other site
1124991005286	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991005287	ABC transporter signature motif; other site
1124991005288	Walker B; other site
1124991005289	ABC transporter; Region: ABC_tran_2; pfam12848
1124991005290	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991005291	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1124991005292	Transmembrane protein 55A; Region: Tmemb_55A; pfam09788
1124991005293	Paraquat-inducible protein A; Region: PqiA; pfam04403
1124991005294	Paraquat-inducible protein A; Region: PqiA; pfam04403
1124991005295	paraquat-inducible protein B; Provisional; Region: PRK10807
1124991005296	mce related protein; Region: MCE; pfam02470
1124991005297	mce related protein; Region: MCE; pfam02470
1124991005298	mce related protein; Region: MCE; pfam02470
1124991005299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1124991005300	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1124991005301	Ribosome modulation factor; Region: RMF; cl01207
1124991005302	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1124991005303	active site 1 [active]
1124991005304	dimer interface [polypeptide binding]; other site
1124991005305	active site 2 [active]
1124991005306	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1124991005307	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1124991005308	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1124991005309	outer membrane protein A; Reviewed; Region: PRK10808
1124991005310	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1124991005311	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1124991005312	ligand binding site [chemical binding]; other site
1124991005313	SOS cell division inhibitor; Provisional; Region: PRK10595
1124991005314	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1124991005315	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1124991005316	TIGR01666 family membrane protein; Region: YCCS
1124991005317	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1124991005318	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1124991005319	DNA helicase IV; Provisional; Region: helD; PRK11054
1124991005320	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1124991005321	Part of AAA domain; Region: AAA_19; pfam13245
1124991005322	Family description; Region: UvrD_C_2; pfam13538
1124991005323	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1124991005324	active site
1124991005325	dimer interfaces [polypeptide binding]; other site
1124991005326	catalytic residues [active]
1124991005327	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1124991005328	heat shock protein HspQ; Provisional; Region: PRK14129
1124991005329	Acylphosphatase; Region: Acylphosphatase; pfam00708
1124991005330	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1124991005331	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
1124991005332	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1124991005333	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1124991005334	[4Fe-4S] binding site [ion binding]; other site
1124991005335	molybdopterin cofactor binding site; other site
1124991005336	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1124991005337	molybdopterin cofactor binding site; other site
1124991005338	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1124991005339	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1124991005340	CPxP  motif; other site
1124991005341	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1124991005342	Uncharacterized membrane protein [Function unknown]; Region: SpmB; cl17667
1124991005343	Uncharacterized membrane protein [Function unknown]; Region: SpmB; cl17667
1124991005344	Predicted acetyltransferase [General function prediction only]; Region: COG2388
1124991005345	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1124991005346	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
1124991005347	Fimbrial protein; Region: Fimbrial; cl01416
1124991005348	Fimbrial protein; Region: Fimbrial; cl01416
1124991005349	outer membrane usher protein FimD; Provisional; Region: PRK15198
1124991005350	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991005351	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991005352	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991005353	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991005354	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991005355	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991005356	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991005357	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991005358	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1124991005359	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1124991005360	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991005361	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991005362	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1124991005363	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1124991005364	HAMP domain; Region: HAMP; pfam00672
1124991005365	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991005366	dimer interface [polypeptide binding]; other site
1124991005367	putative CheW interface [polypeptide binding]; other site
1124991005368	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1124991005369	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1124991005370	DNA binding residues [nucleotide binding]
1124991005371	putative dimer interface [polypeptide binding]; other site
1124991005372	classical (c) SDRs; Region: SDR_c; cd05233
1124991005373	NAD(P) binding site [chemical binding]; other site
1124991005374	active site
1124991005375	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1124991005376	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991005377	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1124991005378	Coenzyme A binding pocket [chemical binding]; other site
1124991005379	ornithine decarboxylase; Provisional; Region: PRK13578
1124991005380	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1124991005381	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1124991005382	homodimer interface [polypeptide binding]; other site
1124991005383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991005384	catalytic residue [active]
1124991005385	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1124991005386	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1124991005387	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_7; cd07585
1124991005388	putative active site [active]
1124991005389	catalytic triad [active]
1124991005390	putative dimer interface [polypeptide binding]; other site
1124991005391	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991005392	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991005393	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991005394	dimerization interface [polypeptide binding]; other site
1124991005395	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1124991005396	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991005397	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1124991005398	dimerization interface [polypeptide binding]; other site
1124991005399	substrate binding pocket [chemical binding]; other site
1124991005400	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1124991005401	EamA-like transporter family; Region: EamA; pfam00892
1124991005402	EamA-like transporter family; Region: EamA; pfam00892
1124991005403	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1124991005404	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991005405	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991005406	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991005407	dimerization interface [polypeptide binding]; other site
1124991005408	Protein of unknown function, DUF486; Region: DUF486; cl01236
1124991005409	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1124991005410	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1124991005411	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1124991005412	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1124991005413	active site
1124991005414	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1124991005415	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1124991005416	active site
1124991005417	metal binding site [ion binding]; metal-binding site
1124991005418	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1124991005419	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1124991005420	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1124991005421	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1124991005422	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1124991005423	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1124991005424	dimer interface [polypeptide binding]; other site
1124991005425	PYR/PP interface [polypeptide binding]; other site
1124991005426	TPP binding site [chemical binding]; other site
1124991005427	substrate binding site [chemical binding]; other site
1124991005428	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1124991005429	Domain of unknown function; Region: EKR; pfam10371
1124991005430	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1124991005431	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991005432	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1124991005433	TPP-binding site [chemical binding]; other site
1124991005434	dimer interface [polypeptide binding]; other site
1124991005435	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1124991005436	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991005437	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1124991005438	putative hydrolase; Validated; Region: PRK09248
1124991005439	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1124991005440	active site
1124991005441	Creatinine amidohydrolase; Region: Creatininase; pfam02633
1124991005442	Na binding site [ion binding]; other site
1124991005443	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1124991005444	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1124991005445	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1124991005446	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1124991005447	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1124991005448	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991005449	Coenzyme A binding pocket [chemical binding]; other site
1124991005450	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1124991005451	catalytic core [active]
1124991005452	hypothetical protein; Validated; Region: PRK01777
1124991005453	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1124991005454	putative coenzyme Q binding site [chemical binding]; other site
1124991005455	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1124991005456	SmpB-tmRNA interface; other site
1124991005457	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
1124991005458	active site
1124991005459	NTP binding site [chemical binding]; other site
1124991005460	metal binding triad [ion binding]; metal-binding site
1124991005461	Prokaryotic E2 family B; Region: Prok-E2_B; pfam14461
1124991005462	ThiF family; Region: ThiF; pfam00899
1124991005463	ATP binding site [chemical binding]; other site
1124991005464	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991005465	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991005466	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991005467	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
1124991005468	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
1124991005469	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1124991005470	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
1124991005471	Bacterial transcriptional regulator; Region: IclR; pfam01614
1124991005472	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1124991005473	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1124991005474	inhibitor site; inhibition site
1124991005475	active site
1124991005476	dimer interface [polypeptide binding]; other site
1124991005477	catalytic residue [active]
1124991005478	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1124991005479	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991005480	putative substrate translocation pore; other site
1124991005481	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1124991005482	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1124991005483	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1124991005484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991005485	metabolite-proton symporter; Region: 2A0106; TIGR00883
1124991005486	putative substrate translocation pore; other site
1124991005487	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1124991005488	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1124991005489	recombination and repair protein; Provisional; Region: PRK10869
1124991005490	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1124991005491	Walker A/P-loop; other site
1124991005492	ATP binding site [chemical binding]; other site
1124991005493	Q-loop/lid; other site
1124991005494	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1124991005495	ABC transporter signature motif; other site
1124991005496	Walker B; other site
1124991005497	D-loop; other site
1124991005498	H-loop/switch region; other site
1124991005499	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1124991005500	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1124991005501	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1124991005502	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1124991005503	dimer interface [polypeptide binding]; other site
1124991005504	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1124991005505	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1124991005506	ligand binding site [chemical binding]; other site
1124991005507	active site
1124991005508	UGI interface [polypeptide binding]; other site
1124991005509	catalytic site [active]
1124991005510	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1124991005511	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1124991005512	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1124991005513	nucleophilic elbow; other site
1124991005514	nucleophilic elbow; other site
1124991005515	catalytic triad; other site
1124991005516	catalytic triad; other site
1124991005517	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1124991005518	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1124991005519	ATP binding site [chemical binding]; other site
1124991005520	Mg++ binding site [ion binding]; other site
1124991005521	motif III; other site
1124991005522	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991005523	nucleotide binding region [chemical binding]; other site
1124991005524	ATP-binding site [chemical binding]; other site
1124991005525	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1124991005526	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991005527	S-adenosylmethionine binding site [chemical binding]; other site
1124991005528	RNA polymerase sigma factor AlgU; Provisional; Region: algU; PRK11923
1124991005529	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991005530	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991005531	DNA binding residues [nucleotide binding]
1124991005532	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1124991005533	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1124991005534	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1124991005535	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1124991005536	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1124991005537	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1124991005538	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
1124991005539	GTP-binding protein LepA; Provisional; Region: PRK05433
1124991005540	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1124991005541	G1 box; other site
1124991005542	putative GEF interaction site [polypeptide binding]; other site
1124991005543	GTP/Mg2+ binding site [chemical binding]; other site
1124991005544	Switch I region; other site
1124991005545	G2 box; other site
1124991005546	G3 box; other site
1124991005547	Switch II region; other site
1124991005548	G4 box; other site
1124991005549	G5 box; other site
1124991005550	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1124991005551	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1124991005552	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1124991005553	signal peptidase I; Provisional; Region: PRK10861
1124991005554	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1124991005555	Catalytic site [active]
1124991005556	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1124991005557	Catalytic site [active]
1124991005558	ribonuclease III; Reviewed; Region: rnc; PRK00102
1124991005559	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1124991005560	dimerization interface [polypeptide binding]; other site
1124991005561	active site
1124991005562	metal binding site [ion binding]; metal-binding site
1124991005563	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1124991005564	dsRNA binding site [nucleotide binding]; other site
1124991005565	GTPase Era; Reviewed; Region: era; PRK00089
1124991005566	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1124991005567	G1 box; other site
1124991005568	GTP/Mg2+ binding site [chemical binding]; other site
1124991005569	Switch I region; other site
1124991005570	G2 box; other site
1124991005571	Switch II region; other site
1124991005572	G3 box; other site
1124991005573	G4 box; other site
1124991005574	G5 box; other site
1124991005575	KH domain; Region: KH_2; pfam07650
1124991005576	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1124991005577	Recombination protein O N terminal; Region: RecO_N; pfam11967
1124991005578	Recombination protein O C terminal; Region: RecO_C; pfam02565
1124991005579	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1124991005580	active site
1124991005581	hydrophilic channel; other site
1124991005582	dimerization interface [polypeptide binding]; other site
1124991005583	catalytic residues [active]
1124991005584	active site lid [active]
1124991005585	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1124991005586	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1124991005587	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1124991005588	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_11; cd07261
1124991005589	putative dimer interface [polypeptide binding]; other site
1124991005590	Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462
1124991005591	EamA-like transporter family; Region: EamA; pfam00892
1124991005592	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1124991005593	EamA-like transporter family; Region: EamA; pfam00892
1124991005594	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1124991005595	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1124991005596	active site
1124991005597	HIGH motif; other site
1124991005598	dimer interface [polypeptide binding]; other site
1124991005599	KMSKS motif; other site
1124991005600	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
1124991005601	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1124991005602	active site
1124991005603	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991005604	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991005605	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1124991005606	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991005607	putative substrate translocation pore; other site
1124991005608	leucine export protein LeuE; Provisional; Region: PRK10958
1124991005609	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1124991005610	nucleoside/Zn binding site; other site
1124991005611	dimer interface [polypeptide binding]; other site
1124991005612	catalytic motif [active]
1124991005613	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1124991005614	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991005615	substrate binding pocket [chemical binding]; other site
1124991005616	membrane-bound complex binding site; other site
1124991005617	hinge residues; other site
1124991005618	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1124991005619	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1124991005620	catalytic residue [active]
1124991005621	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1124991005622	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1124991005623	dimerization interface [polypeptide binding]; other site
1124991005624	ATP binding site [chemical binding]; other site
1124991005625	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1124991005626	dimerization interface [polypeptide binding]; other site
1124991005627	ATP binding site [chemical binding]; other site
1124991005628	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1124991005629	putative active site [active]
1124991005630	catalytic triad [active]
1124991005631	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
1124991005632	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1124991005633	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1124991005634	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1124991005635	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1124991005636	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1124991005637	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1124991005638	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991005639	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1124991005640	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1124991005641	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1124991005642	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1124991005643	HAMP domain; Region: HAMP; pfam00672
1124991005644	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991005645	dimer interface [polypeptide binding]; other site
1124991005646	phosphorylation site [posttranslational modification]
1124991005647	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991005648	ATP binding site [chemical binding]; other site
1124991005649	Mg2+ binding site [ion binding]; other site
1124991005650	G-X-G motif; other site
1124991005651	hypothetical protein; Provisional; Region: PRK10722
1124991005652	response regulator GlrR; Provisional; Region: PRK15115
1124991005653	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991005654	active site
1124991005655	phosphorylation site [posttranslational modification]
1124991005656	intermolecular recognition site; other site
1124991005657	dimerization interface [polypeptide binding]; other site
1124991005658	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991005659	Walker A motif; other site
1124991005660	ATP binding site [chemical binding]; other site
1124991005661	Walker B motif; other site
1124991005662	arginine finger; other site
1124991005663	NAD synthetase; Provisional; Region: PRK13981
1124991005664	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1124991005665	multimer interface [polypeptide binding]; other site
1124991005666	active site
1124991005667	catalytic triad [active]
1124991005668	protein interface 1 [polypeptide binding]; other site
1124991005669	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1124991005670	homodimer interface [polypeptide binding]; other site
1124991005671	NAD binding pocket [chemical binding]; other site
1124991005672	ATP binding pocket [chemical binding]; other site
1124991005673	Mg binding site [ion binding]; other site
1124991005674	active-site loop [active]
1124991005675	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1124991005676	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1124991005677	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1124991005678	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1124991005679	heme-binding site [chemical binding]; other site
1124991005680	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1124991005681	FAD binding pocket [chemical binding]; other site
1124991005682	FAD binding motif [chemical binding]; other site
1124991005683	phosphate binding motif [ion binding]; other site
1124991005684	beta-alpha-beta structure motif; other site
1124991005685	NAD binding pocket [chemical binding]; other site
1124991005686	Heme binding  pocket [chemical binding]; other site
1124991005687	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1124991005688	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1124991005689	dimer interface [polypeptide binding]; other site
1124991005690	active site
1124991005691	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1124991005692	folate binding site [chemical binding]; other site
1124991005693	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1124991005694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1124991005695	putative substrate translocation pore; other site
1124991005696	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1124991005697	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1124991005698	active site
1124991005699	dimerization interface [polypeptide binding]; other site
1124991005700	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1124991005701	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1124991005702	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1124991005703	Rrf2 family protein; Region: rrf2_super; TIGR00738
1124991005704	cysteine desulfurase; Provisional; Region: PRK14012
1124991005705	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1124991005706	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991005707	catalytic residue [active]
1124991005708	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1124991005709	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1124991005710	trimerization site [polypeptide binding]; other site
1124991005711	active site
1124991005712	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1124991005713	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1124991005714	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1124991005715	HSP70 interaction site [polypeptide binding]; other site
1124991005716	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1124991005717	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1124991005718	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1124991005719	nucleotide binding site [chemical binding]; other site
1124991005720	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1124991005721	SBD interface [polypeptide binding]; other site
1124991005722	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1124991005723	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991005724	catalytic loop [active]
1124991005725	iron binding site [ion binding]; other site
1124991005726	hypothetical protein; Provisional; Region: PRK10721
1124991005727	aminopeptidase B; Provisional; Region: PRK05015
1124991005728	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1124991005729	interface (dimer of trimers) [polypeptide binding]; other site
1124991005730	Substrate-binding/catalytic site; other site
1124991005731	Zn-binding sites [ion binding]; other site
1124991005732	SseB protein; Region: SseB; cl06279
1124991005733	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1124991005734	MG2 domain; Region: A2M_N; pfam01835
1124991005735	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1124991005736	surface patch; other site
1124991005737	thioester region; other site
1124991005738	penicillin-binding protein 1C; Provisional; Region: PRK11240
1124991005739	Transglycosylase; Region: Transgly; pfam00912
1124991005740	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1124991005741	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1124991005742	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1124991005743	active site
1124991005744	multimer interface [polypeptide binding]; other site
1124991005745	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991005746	Ligand Binding Site [chemical binding]; other site
1124991005747	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1124991005748	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991005749	FeS/SAM binding site; other site
1124991005750	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1124991005751	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1124991005752	Helix-turn-helix domain; Region: HTH_25; pfam13413
1124991005753	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1124991005754	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1124991005755	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1124991005756	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1124991005757	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1124991005758	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1124991005759	dimer interface [polypeptide binding]; other site
1124991005760	motif 1; other site
1124991005761	active site
1124991005762	motif 2; other site
1124991005763	motif 3; other site
1124991005764	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1124991005765	anticodon binding site; other site
1124991005766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1124991005767	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1124991005768	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1124991005769	Trp docking motif [polypeptide binding]; other site
1124991005770	GTP-binding protein Der; Reviewed; Region: PRK00093
1124991005771	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1124991005772	G1 box; other site
1124991005773	GTP/Mg2+ binding site [chemical binding]; other site
1124991005774	Switch I region; other site
1124991005775	G2 box; other site
1124991005776	Switch II region; other site
1124991005777	G3 box; other site
1124991005778	G4 box; other site
1124991005779	G5 box; other site
1124991005780	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1124991005781	G1 box; other site
1124991005782	GTP/Mg2+ binding site [chemical binding]; other site
1124991005783	Switch I region; other site
1124991005784	G2 box; other site
1124991005785	G3 box; other site
1124991005786	Switch II region; other site
1124991005787	G4 box; other site
1124991005788	G5 box; other site
1124991005789	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1124991005790	active site
1124991005791	Zn binding site [ion binding]; other site
1124991005792	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1124991005793	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1124991005794	putative acetyltransferase; Provisional; Region: PRK03624
1124991005795	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991005796	Coenzyme A binding pocket [chemical binding]; other site
1124991005797	Bacterial OB fold (BOF) protein; Region: BOF; cl01196
1124991005798	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1124991005799	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1124991005800	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1124991005801	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1124991005802	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1124991005803	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991005804	dimer interface [polypeptide binding]; other site
1124991005805	conserved gate region; other site
1124991005806	putative PBP binding loops; other site
1124991005807	ABC-ATPase subunit interface; other site
1124991005808	sulfate transport protein; Provisional; Region: cysT; CHL00187
1124991005809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991005810	dimer interface [polypeptide binding]; other site
1124991005811	conserved gate region; other site
1124991005812	putative PBP binding loops; other site
1124991005813	ABC-ATPase subunit interface; other site
1124991005814	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1124991005815	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991005816	Walker A/P-loop; other site
1124991005817	ATP binding site [chemical binding]; other site
1124991005818	Q-loop/lid; other site
1124991005819	ABC transporter signature motif; other site
1124991005820	Walker B; other site
1124991005821	D-loop; other site
1124991005822	H-loop/switch region; other site
1124991005823	cysteine synthase B; Region: cysM; TIGR01138
1124991005824	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1124991005825	dimer interface [polypeptide binding]; other site
1124991005826	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991005827	catalytic residue [active]
1124991005828	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1124991005829	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991005830	Coenzyme A binding pocket [chemical binding]; other site
1124991005831	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1124991005832	S-adenosylmethionine binding site [chemical binding]; other site
1124991005833	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1124991005834	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1124991005835	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1124991005836	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991005837	Helix-turn-helix domain; Region: HTH_18; pfam12833
1124991005838	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1124991005839	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1124991005840	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
1124991005841	FecR protein; Region: FecR; pfam04773
1124991005842	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1124991005843	dimer interface [polypeptide binding]; other site
1124991005844	putative tRNA-binding site [nucleotide binding]; other site
1124991005845	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1124991005846	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991005847	amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924
1124991005848	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991005849	putative substrate translocation pore; other site
1124991005850	POT family; Region: PTR2; cl17359
1124991005851	drug efflux system protein MdtG; Provisional; Region: PRK09874
1124991005852	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991005853	putative substrate translocation pore; other site
1124991005854	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1124991005855	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1124991005856	putative acyl-acceptor binding pocket; other site
1124991005857	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1124991005858	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991005859	active site
1124991005860	phosphorylation site [posttranslational modification]
1124991005861	intermolecular recognition site; other site
1124991005862	dimerization interface [polypeptide binding]; other site
1124991005863	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991005864	DNA binding residues [nucleotide binding]
1124991005865	dimerization interface [polypeptide binding]; other site
1124991005866	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1124991005867	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1124991005868	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991005869	dimer interface [polypeptide binding]; other site
1124991005870	phosphorylation site [posttranslational modification]
1124991005871	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991005872	ATP binding site [chemical binding]; other site
1124991005873	Mg2+ binding site [ion binding]; other site
1124991005874	G-X-G motif; other site
1124991005875	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1124991005876	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991005877	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1124991005878	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1124991005879	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1124991005880	putative [Fe4-S4] binding site [ion binding]; other site
1124991005881	putative molybdopterin cofactor binding site [chemical binding]; other site
1124991005882	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1124991005883	putative molybdopterin cofactor binding site; other site
1124991005884	BssS protein family; Region: BssS; cl08210
1124991005885	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1124991005886	active site
1124991005887	substrate binding pocket [chemical binding]; other site
1124991005888	dimer interface [polypeptide binding]; other site
1124991005889	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991005890	non-specific DNA binding site [nucleotide binding]; other site
1124991005891	salt bridge; other site
1124991005892	sequence-specific DNA binding site [nucleotide binding]; other site
1124991005893	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1124991005894	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991005895	DNA-binding site [nucleotide binding]; DNA binding site
1124991005896	RNA-binding motif; other site
1124991005897	Dextransucrase DSRB; Region: DSRB; cl11680
1124991005898	magnesium transport protein MgtC; Provisional; Region: PRK15385
1124991005899	MgtC family; Region: MgtC; pfam02308
1124991005900	transcriptional activator FlhD; Provisional; Region: PRK02909
1124991005901	transcriptional activator FlhC; Provisional; Region: PRK12722
1124991005902	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1124991005903	flagellar motor protein MotA; Validated; Region: PRK09110
1124991005904	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1124991005905	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1124991005906	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1124991005907	ligand binding site [chemical binding]; other site
1124991005908	chemotaxis protein CheA; Provisional; Region: PRK10547
1124991005909	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1124991005910	putative binding surface; other site
1124991005911	active site
1124991005912	CheY binding; Region: CheY-binding; pfam09078
1124991005913	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1124991005914	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991005915	ATP binding site [chemical binding]; other site
1124991005916	Mg2+ binding site [ion binding]; other site
1124991005917	G-X-G motif; other site
1124991005918	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1124991005919	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1124991005920	putative CheA interaction surface; other site
1124991005921	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1124991005922	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1124991005923	dimer interface [polypeptide binding]; other site
1124991005924	ligand binding site [chemical binding]; other site
1124991005925	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991005926	dimerization interface [polypeptide binding]; other site
1124991005927	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991005928	dimer interface [polypeptide binding]; other site
1124991005929	putative CheW interface [polypeptide binding]; other site
1124991005930	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1124991005931	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1124991005932	dimer interface [polypeptide binding]; other site
1124991005933	ligand binding site [chemical binding]; other site
1124991005934	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991005935	dimerization interface [polypeptide binding]; other site
1124991005936	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991005937	dimer interface [polypeptide binding]; other site
1124991005938	putative CheW interface [polypeptide binding]; other site
1124991005939	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1124991005940	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1124991005941	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991005942	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1124991005943	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991005944	active site
1124991005945	phosphorylation site [posttranslational modification]
1124991005946	intermolecular recognition site; other site
1124991005947	dimerization interface [polypeptide binding]; other site
1124991005948	CheB methylesterase; Region: CheB_methylest; pfam01339
1124991005949	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1124991005950	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991005951	active site
1124991005952	phosphorylation site [posttranslational modification]
1124991005953	intermolecular recognition site; other site
1124991005954	dimerization interface [polypeptide binding]; other site
1124991005955	Chemotaxis phosphatase, CheZ; Region: CheZ; cl01219
1124991005956	F0F1 ATP synthase subunit alpha; Validated; Region: PRK06763
1124991005957	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1124991005958	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1124991005959	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1124991005960	FHIPEP family; Region: FHIPEP; pfam00771
1124991005961	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
1124991005962	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
1124991005963	FlgN protein; Region: FlgN; cl09176
1124991005964	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1124991005965	SAF-like; Region: SAF_2; pfam13144
1124991005966	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1124991005967	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1124991005968	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1124991005969	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1124991005970	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1124991005971	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1124991005972	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1124991005973	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1124991005974	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1124991005975	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1124991005976	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1124991005977	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1124991005978	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1124991005979	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1124991005980	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1124991005981	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1124991005982	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1124991005983	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1124991005984	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1124991005985	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1124991005986	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12698
1124991005987	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1124991005988	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1124991005989	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1124991005990	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1124991005991	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1124991005992	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1124991005993	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1124991005994	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1124991005995	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1124991005996	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991005997	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991005998	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991005999	putative effector binding pocket; other site
1124991006000	dimerization interface [polypeptide binding]; other site
1124991006001	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1124991006002	classical (c) SDRs; Region: SDR_c; cd05233
1124991006003	NAD(P) binding site [chemical binding]; other site
1124991006004	active site
1124991006005	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1124991006006	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1124991006007	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1124991006008	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
1124991006009	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1124991006010	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1124991006011	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1124991006012	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1124991006013	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1124991006014	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1124991006015	Flagellar FliJ protein; Region: FliJ; pfam02050
1124991006016	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1124991006017	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1124991006018	Walker A motif/ATP binding site; other site
1124991006019	Walker B motif; other site
1124991006020	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1124991006021	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1124991006022	Flagellar assembly protein FliH; Region: FliH; pfam02108
1124991006023	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1124991006024	FliG C-terminal domain; Region: FliG_C; pfam01706
1124991006025	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1124991006026	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1124991006027	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1124991006028	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1124991006029	META domain; Region: META; cl01245
1124991006030	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1124991006031	Domain of unknown function (DUF4377); Region: DUF4377; pfam14302
1124991006032	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1124991006033	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1124991006034	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
1124991006035	CrcB-like protein; Region: CRCB; cl09114
1124991006036	Flagellar protein FliT; Region: FliT; cl05125
1124991006037	flagellar protein FliS; Validated; Region: fliS; PRK05685
1124991006038	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1124991006039	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1124991006040	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1124991006041	flagellin; Validated; Region: PRK06819
1124991006042	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1124991006043	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1124991006044	flagellin; Validated; Region: PRK06819
1124991006045	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1124991006046	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1124991006047	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1124991006048	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991006049	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1124991006050	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991006051	DNA binding residues [nucleotide binding]
1124991006052	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1124991006053	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1124991006054	Predicted transcriptional regulator [Transcription]; Region: COG3905
1124991006055	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1124991006056	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1124991006057	Glutamate binding site [chemical binding]; other site
1124991006058	NAD binding site [chemical binding]; other site
1124991006059	catalytic residues [active]
1124991006060	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1124991006061	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1124991006062	Na binding site [ion binding]; other site
1124991006063	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1124991006064	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1124991006065	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1124991006066	active site
1124991006067	Sulfatase; Region: Sulfatase; cl17466
1124991006068	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1124991006069	hypothetical protein; Provisional; Region: PRK10649
1124991006070	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1124991006071	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1124991006072	cryptic adenine deaminase; Provisional; Region: PRK10027
1124991006073	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1124991006074	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1124991006075	active site
1124991006076	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1124991006077	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1124991006078	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1124991006079	Walker A/P-loop; other site
1124991006080	ATP binding site [chemical binding]; other site
1124991006081	Q-loop/lid; other site
1124991006082	ABC transporter signature motif; other site
1124991006083	Walker B; other site
1124991006084	D-loop; other site
1124991006085	H-loop/switch region; other site
1124991006086	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991006087	dimer interface [polypeptide binding]; other site
1124991006088	conserved gate region; other site
1124991006089	putative PBP binding loops; other site
1124991006090	ABC-ATPase subunit interface; other site
1124991006091	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991006092	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1124991006093	substrate binding pocket [chemical binding]; other site
1124991006094	membrane-bound complex binding site; other site
1124991006095	hinge residues; other site
1124991006096	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1124991006097	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1124991006098	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1124991006099	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1124991006100	putative acyl-acceptor binding pocket; other site
1124991006101	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1124991006102	cystathionine beta-lyase; Provisional; Region: PRK09028
1124991006103	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1124991006104	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991006105	catalytic residue [active]
1124991006106	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1124991006107	aromatic amino acid transport protein; Region: araaP; TIGR00837
1124991006108	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1124991006109	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991006110	catalytic loop [active]
1124991006111	iron binding site [ion binding]; other site
1124991006112	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1124991006113	dimer interface [polypeptide binding]; other site
1124991006114	putative radical transfer pathway; other site
1124991006115	diiron center [ion binding]; other site
1124991006116	tyrosyl radical; other site
1124991006117	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1124991006118	ATP cone domain; Region: ATP-cone; pfam03477
1124991006119	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1124991006120	active site
1124991006121	dimer interface [polypeptide binding]; other site
1124991006122	catalytic residues [active]
1124991006123	effector binding site; other site
1124991006124	R2 peptide binding site; other site
1124991006125	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1124991006126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006127	S-adenosylmethionine binding site [chemical binding]; other site
1124991006128	DNA gyrase subunit A; Validated; Region: PRK05560
1124991006129	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1124991006130	CAP-like domain; other site
1124991006131	active site
1124991006132	primary dimer interface [polypeptide binding]; other site
1124991006133	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006134	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006135	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006136	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006137	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006138	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1124991006139	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1124991006140	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991006141	dimer interface [polypeptide binding]; other site
1124991006142	phosphorylation site [posttranslational modification]
1124991006143	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991006144	ATP binding site [chemical binding]; other site
1124991006145	Mg2+ binding site [ion binding]; other site
1124991006146	G-X-G motif; other site
1124991006147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991006148	active site
1124991006149	phosphorylation site [posttranslational modification]
1124991006150	intermolecular recognition site; other site
1124991006151	dimerization interface [polypeptide binding]; other site
1124991006152	transcriptional regulator RcsB; Provisional; Region: PRK10840
1124991006153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991006154	active site
1124991006155	phosphorylation site [posttranslational modification]
1124991006156	intermolecular recognition site; other site
1124991006157	dimerization interface [polypeptide binding]; other site
1124991006158	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991006159	DNA binding residues [nucleotide binding]
1124991006160	dimerization interface [polypeptide binding]; other site
1124991006161	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1124991006162	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991006163	ATP binding site [chemical binding]; other site
1124991006164	Mg2+ binding site [ion binding]; other site
1124991006165	G-X-G motif; other site
1124991006166	Hpt domain; Region: Hpt; pfam01627
1124991006167	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1124991006168	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1124991006169	Int/Topo IB signature motif; other site
1124991006170	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1124991006171	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1124991006172	dimer interface [polypeptide binding]; other site
1124991006173	ssDNA binding site [nucleotide binding]; other site
1124991006174	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1124991006175	ERF superfamily; Region: ERF; pfam04404
1124991006176	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991006177	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991006178	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991006179	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991006180	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991006181	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991006182	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991006183	DNA-binding site [nucleotide binding]; DNA binding site
1124991006184	RNA-binding motif; other site
1124991006185	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1124991006186	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1124991006187	putative acyl-acceptor binding pocket; other site
1124991006188	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991006189	Sel1-like repeats; Region: SEL1; smart00671
1124991006190	Sel1-like repeats; Region: SEL1; smart00671
1124991006191	Sel1-like repeats; Region: SEL1; smart00671
1124991006192	Sel1-like repeats; Region: SEL1; smart00671
1124991006193	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991006194	Ligand Binding Site [chemical binding]; other site
1124991006195	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1124991006196	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1124991006197	putative dimer interface [polypeptide binding]; other site
1124991006198	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1124991006199	catalytic residues [active]
1124991006200	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1124991006201	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991006202	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991006203	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991006204	Phage terminase, small subunit; Region: Terminase_4; cl01525
1124991006205	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1124991006206	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1124991006207	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1124991006208	MPN+ (JAMM) motif; other site
1124991006209	Zinc-binding site [ion binding]; other site
1124991006210	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1124991006211	NlpC/P60 family; Region: NLPC_P60; pfam00877
1124991006212	Phage-related protein, tail component [Function unknown]; Region: COG4723
1124991006213	Phage-related protein, tail component [Function unknown]; Region: COG4733
1124991006214	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1124991006215	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1124991006216	Interdomain contacts; other site
1124991006217	Cytokine receptor motif; other site
1124991006218	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1124991006219	Fibronectin type III protein; Region: DUF3672; pfam12421
1124991006220	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1124991006221	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006222	S-adenosylmethionine binding site [chemical binding]; other site
1124991006223	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1124991006224	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006225	S-adenosylmethionine binding site [chemical binding]; other site
1124991006226	hypothetical protein; Provisional; Region: PRK13687
1124991006227	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1124991006228	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991006229	Catalytic site [active]
1124991006230	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1124991006231	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1124991006232	active site
1124991006233	DNA binding site [nucleotide binding]
1124991006234	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1124991006235	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1124991006236	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1124991006237	putative ADP-binding pocket [chemical binding]; other site
1124991006238	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1124991006239	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1124991006240	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
1124991006241	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1124991006242	Baseplate J-like protein; Region: Baseplate_J; cl01294
1124991006243	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
1124991006244	Phage Tail Collar Domain; Region: Collar; pfam07484
1124991006245	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1124991006246	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1124991006247	Domain of unknown function (DUF1287); Region: DUF1287; pfam06940
1124991006248	lipoprotein; Provisional; Region: PRK10540
1124991006249	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1124991006250	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991006251	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991006252	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1124991006253	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1124991006254	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1124991006255	putative active site [active]
1124991006256	aromatic amino acid exporter; Provisional; Region: PRK11689
1124991006257	EamA-like transporter family; Region: EamA; pfam00892
1124991006258	Bacterial protein of unknown function (DUF924); Region: DUF924; pfam06041
1124991006259	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1124991006260	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991006261	acid-resistance membrane protein; Provisional; Region: PRK10209
1124991006262	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
1124991006263	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991006264	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991006265	non-specific DNA binding site [nucleotide binding]; other site
1124991006266	salt bridge; other site
1124991006267	sequence-specific DNA binding site [nucleotide binding]; other site
1124991006268	AzlC protein; Region: AzlC; pfam03591
1124991006269	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1124991006270	Isochorismatase family; Region: Isochorismatase; pfam00857
1124991006271	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1124991006272	catalytic triad [active]
1124991006273	conserved cis-peptide bond; other site
1124991006274	sensor protein QseC; Provisional; Region: PRK10337
1124991006275	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991006276	dimer interface [polypeptide binding]; other site
1124991006277	phosphorylation site [posttranslational modification]
1124991006278	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991006279	ATP binding site [chemical binding]; other site
1124991006280	Mg2+ binding site [ion binding]; other site
1124991006281	G-X-G motif; other site
1124991006282	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1124991006283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991006284	active site
1124991006285	phosphorylation site [posttranslational modification]
1124991006286	intermolecular recognition site; other site
1124991006287	dimerization interface [polypeptide binding]; other site
1124991006288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991006289	DNA binding site [nucleotide binding]
1124991006290	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1124991006291	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1124991006292	Predicted flavoprotein [General function prediction only]; Region: COG0431
1124991006293	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1124991006294	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1124991006295	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1124991006296	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1124991006297	generic binding surface II; other site
1124991006298	generic binding surface I; other site
1124991006299	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1124991006300	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1124991006301	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1124991006302	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1124991006303	active site
1124991006304	GMP synthase; Reviewed; Region: guaA; PRK00074
1124991006305	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1124991006306	AMP/PPi binding site [chemical binding]; other site
1124991006307	candidate oxyanion hole; other site
1124991006308	catalytic triad [active]
1124991006309	potential glutamine specificity residues [chemical binding]; other site
1124991006310	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1124991006311	ATP Binding subdomain [chemical binding]; other site
1124991006312	Ligand Binding sites [chemical binding]; other site
1124991006313	Dimerization subdomain; other site
1124991006314	Isochorismatase family; Region: Isochorismatase; pfam00857
1124991006315	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1124991006316	catalytic triad [active]
1124991006317	dimer interface [polypeptide binding]; other site
1124991006318	conserved cis-peptide bond; other site
1124991006319	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1124991006320	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1124991006321	active site
1124991006322	Transmembrane secretion effector; Region: MFS_3; pfam05977
1124991006323	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991006324	putative substrate translocation pore; other site
1124991006325	Predicted integral membrane proteins containing uncharacterized repeats [Function unknown]; Region: COG5563
1124991006326	probable extracellular repeat, HAF family; Region: HAF_rpt; TIGR02913
1124991006327	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1124991006328	Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins; Region: PI-PLCc_BcPLC_like; cd08586
1124991006329	active site
1124991006330	catalytic site [active]
1124991006331	putative metal binding site [ion binding]; other site
1124991006332	YadA-like C-terminal region; Region: YadA; pfam03895
1124991006333	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1124991006334	metal ion-dependent adhesion site (MIDAS); other site
1124991006335	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1124991006336	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006337	S-adenosylmethionine binding site [chemical binding]; other site
1124991006338	hypothetical protein; Provisional; Region: PRK11469
1124991006339	Domain of unknown function DUF; Region: DUF204; pfam02659
1124991006340	Domain of unknown function DUF; Region: DUF204; pfam02659
1124991006341	hypothetical protein; Provisional; Region: PRK02913
1124991006342	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1124991006343	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1124991006344	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1124991006345	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1124991006346	active pocket/dimerization site; other site
1124991006347	active site
1124991006348	phosphorylation site [posttranslational modification]
1124991006349	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1124991006350	active site
1124991006351	phosphorylation site [posttranslational modification]
1124991006352	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1124991006353	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1124991006354	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1124991006355	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1124991006356	putative active site [active]
1124991006357	putative CoA binding site [chemical binding]; other site
1124991006358	nudix motif; other site
1124991006359	metal binding site [ion binding]; metal-binding site
1124991006360	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1124991006361	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1124991006362	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1124991006363	hypothetical protein; Provisional; Region: PRK05114
1124991006364	YebF-like protein; Region: YebF; cl10126
1124991006365	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1124991006366	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1124991006367	Ferritin-like domain; Region: Ferritin; pfam00210
1124991006368	ferroxidase diiron center [ion binding]; other site
1124991006369	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
1124991006370	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1124991006371	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1124991006372	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1124991006373	GAF domain; Region: GAF_2; pfam13185
1124991006374	ProP expression regulator; Provisional; Region: PRK04950
1124991006375	ProQ/FINO family; Region: ProQ; pfam04352
1124991006376	carboxy-terminal protease; Provisional; Region: PRK11186
1124991006377	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1124991006378	protein binding site [polypeptide binding]; other site
1124991006379	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1124991006380	Catalytic dyad [active]
1124991006381	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1124991006382	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1124991006383	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1124991006384	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1124991006385	DNA binding site [nucleotide binding]
1124991006386	active site
1124991006387	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1124991006388	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1124991006389	dimer interface [polypeptide binding]; other site
1124991006390	active site
1124991006391	Schiff base residues; other site
1124991006392	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1124991006393	Protein of unknown function (DUF3999); Region: DUF3999; pfam13163
1124991006394	hypothetical protein; Provisional; Region: PRK10613
1124991006395	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1124991006396	putative ATP binding site [chemical binding]; other site
1124991006397	putative substrate binding site [chemical binding]; other site
1124991006398	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991006399	Ligand Binding Site [chemical binding]; other site
1124991006400	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991006401	Ligand Binding Site [chemical binding]; other site
1124991006402	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991006403	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991006404	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1124991006405	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1124991006406	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
1124991006407	DNA-specific endonuclease I; Provisional; Region: PRK15137
1124991006408	Endonuclease I; Region: Endonuclease_1; cl01003
1124991006409	hypothetical protein; Provisional; Region: PRK10536
1124991006410	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1124991006411	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1124991006412	FAD binding pocket [chemical binding]; other site
1124991006413	FAD binding motif [chemical binding]; other site
1124991006414	phosphate binding motif [ion binding]; other site
1124991006415	NAD binding pocket [chemical binding]; other site
1124991006416	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
1124991006417	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1124991006418	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1124991006419	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1124991006420	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1124991006421	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1124991006422	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991006423	DNA-binding site [nucleotide binding]; DNA binding site
1124991006424	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991006425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991006426	homodimer interface [polypeptide binding]; other site
1124991006427	catalytic residue [active]
1124991006428	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1124991006429	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1124991006430	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991006431	putative DNA binding site [nucleotide binding]; other site
1124991006432	putative Zn2+ binding site [ion binding]; other site
1124991006433	AsnC family; Region: AsnC_trans_reg; pfam01037
1124991006434	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
1124991006435	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
1124991006436	N- and C-terminal domain interface [polypeptide binding]; other site
1124991006437	active site
1124991006438	MgATP binding site [chemical binding]; other site
1124991006439	catalytic site [active]
1124991006440	metal binding site [ion binding]; metal-binding site
1124991006441	carbohydrate binding site [chemical binding]; other site
1124991006442	putative homodimer interface [polypeptide binding]; other site
1124991006443	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991006444	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991006445	TM-ABC transporter signature motif; other site
1124991006446	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991006447	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991006448	TM-ABC transporter signature motif; other site
1124991006449	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1124991006450	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1124991006451	Walker A/P-loop; other site
1124991006452	ATP binding site [chemical binding]; other site
1124991006453	Q-loop/lid; other site
1124991006454	ABC transporter signature motif; other site
1124991006455	Walker B; other site
1124991006456	D-loop; other site
1124991006457	H-loop/switch region; other site
1124991006458	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1124991006459	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1124991006460	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1124991006461	ligand binding site [chemical binding]; other site
1124991006462	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
1124991006463	putative deacylase active site [active]
1124991006464	Cation transport protein; Region: TrkH; cl17365
1124991006465	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1124991006466	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1124991006467	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1124991006468	GTP-binding protein YchF; Reviewed; Region: PRK09601
1124991006469	YchF GTPase; Region: YchF; cd01900
1124991006470	G1 box; other site
1124991006471	GTP/Mg2+ binding site [chemical binding]; other site
1124991006472	Switch I region; other site
1124991006473	G2 box; other site
1124991006474	Switch II region; other site
1124991006475	G3 box; other site
1124991006476	G4 box; other site
1124991006477	G5 box; other site
1124991006478	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1124991006479	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1124991006480	putative active site [active]
1124991006481	catalytic residue [active]
1124991006482	Protein of unknown function (DUF2583); Region: DUF2583; cl11676
1124991006483	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1124991006484	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1124991006485	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991006486	active site
1124991006487	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1124991006488	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1124991006489	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1124991006490	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1124991006491	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1124991006492	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1124991006493	tRNA; other site
1124991006494	putative tRNA binding site [nucleotide binding]; other site
1124991006495	putative NADP binding site [chemical binding]; other site
1124991006496	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1124991006497	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1124991006498	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1124991006499	RF-1 domain; Region: RF-1; pfam00472
1124991006500	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1124991006501	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006502	hypothetical protein; Provisional; Region: PRK10941
1124991006503	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1124991006504	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1124991006505	binding surface
1124991006506	TPR motif; other site
1124991006507	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK12457
1124991006508	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1124991006509	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1124991006510	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1124991006511	putative transporter; Provisional; Region: PRK11660
1124991006512	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1124991006513	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1124991006514	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1124991006515	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1124991006516	putative ligand binding site [chemical binding]; other site
1124991006517	NAD binding site [chemical binding]; other site
1124991006518	dimerization interface [polypeptide binding]; other site
1124991006519	catalytic site [active]
1124991006520	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1124991006521	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
1124991006522	Citrate transporter; Region: CitMHS; pfam03600
1124991006523	Protein of unknown function (DUF1439); Region: DUF1439; cl06345
1124991006524	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1124991006525	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991006526	putative substrate translocation pore; other site
1124991006527	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1124991006528	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1124991006529	integral membrane protein MviN; Region: mviN; TIGR01695
1124991006530	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1124991006531	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1124991006532	Leucine rich repeat; Region: LRR_8; pfam13855
1124991006533	Leucine-rich repeats; other site
1124991006534	Substrate binding site [chemical binding]; other site
1124991006535	Leucine rich repeat; Region: LRR_8; pfam13855
1124991006536	Leucine rich repeat; Region: LRR_8; pfam13855
1124991006537	Leucine rich repeat; Region: LRR_8; pfam13855
1124991006538	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1124991006539	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1124991006540	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1124991006541	active site
1124991006542	HIGH motif; other site
1124991006543	KMSK motif region; other site
1124991006544	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1124991006545	tRNA binding surface [nucleotide binding]; other site
1124991006546	anticodon binding site; other site
1124991006547	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1124991006548	putative metal binding site [ion binding]; other site
1124991006549	copper homeostasis protein CutC; Provisional; Region: PRK11572
1124991006550	Glycosyl hydrolases related to GH101 family; Region: GHL; pfam11308
1124991006551	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1124991006552	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006553	S-adenosylmethionine binding site [chemical binding]; other site
1124991006554	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006555	S-adenosylmethionine binding site [chemical binding]; other site
1124991006556	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1124991006557	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1124991006558	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1124991006559	dimer interface [polypeptide binding]; other site
1124991006560	anticodon binding site; other site
1124991006561	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1124991006562	homodimer interface [polypeptide binding]; other site
1124991006563	motif 1; other site
1124991006564	active site
1124991006565	motif 2; other site
1124991006566	GAD domain; Region: GAD; pfam02938
1124991006567	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1124991006568	active site
1124991006569	motif 3; other site
1124991006570	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1124991006571	nudix motif; other site
1124991006572	hypothetical protein; Validated; Region: PRK00110
1124991006573	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1124991006574	active site
1124991006575	putative DNA-binding cleft [nucleotide binding]; other site
1124991006576	dimer interface [polypeptide binding]; other site
1124991006577	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1124991006578	RuvA N terminal domain; Region: RuvA_N; pfam01330
1124991006579	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1124991006580	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1124991006581	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991006582	Walker A motif; other site
1124991006583	ATP binding site [chemical binding]; other site
1124991006584	Walker B motif; other site
1124991006585	arginine finger; other site
1124991006586	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1124991006587	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1124991006588	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1124991006589	catalytic triad [active]
1124991006590	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1124991006591	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991006592	ABC-ATPase subunit  interface; other site
1124991006593	dimer interface [polypeptide binding]; other site
1124991006594	putative PBP binding regions; other site
1124991006595	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1124991006596	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1124991006597	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1124991006598	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1124991006599	metal binding site [ion binding]; metal-binding site
1124991006600	putative peptidase; Provisional; Region: PRK11649
1124991006601	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1124991006602	Peptidase family M23; Region: Peptidase_M23; pfam01551
1124991006603	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1124991006604	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1124991006605	putative acyl-acceptor binding pocket; other site
1124991006606	integrase; Provisional; Region: int; PHA02601
1124991006607	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991006608	active site
1124991006609	DNA binding site [nucleotide binding]
1124991006610	Int/Topo IB signature motif; other site
1124991006611	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
1124991006612	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1124991006613	DksA-like zinc finger domain containing protein; Region: PHA00080
1124991006614	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1124991006615	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1124991006616	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991006617	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991006618	non-specific DNA binding site [nucleotide binding]; other site
1124991006619	salt bridge; other site
1124991006620	sequence-specific DNA binding site [nucleotide binding]; other site
1124991006621	Domain of unknown function (DUF955); Region: DUF955; cl01076
1124991006622	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1124991006623	Phage portal protein; Region: Phage_portal; pfam04860
1124991006624	terminase ATPase subunit; Provisional; Region: P; PHA02535
1124991006625	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1124991006626	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
1124991006627	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
1124991006628	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1124991006629	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1124991006630	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1124991006631	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1124991006632	catalytic residues [active]
1124991006633	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1124991006634	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1124991006635	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1124991006636	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1124991006637	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1124991006638	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1124991006639	baseplate assembly protein; Provisional; Region: J; PHA02568
1124991006640	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1124991006641	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1124991006642	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1124991006643	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1124991006644	Domain of unknown function (DUF4062); Region: DUF4062; pfam13271
1124991006645	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1124991006646	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1124991006647	Phage tail tube protein FII; Region: Phage_tube; pfam04985
1124991006648	major tail sheath protein; Provisional; Region: FI; PHA02560
1124991006649	tail protein; Provisional; Region: D; PHA02561
1124991006650	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1124991006651	pyruvate kinase; Provisional; Region: PRK05826
1124991006652	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1124991006653	domain interfaces; other site
1124991006654	active site
1124991006655	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1124991006656	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1124991006657	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1124991006658	putative active site [active]
1124991006659	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1124991006660	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1124991006661	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1124991006662	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1124991006663	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1124991006664	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1124991006665	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991006666	active site
1124991006667	phosphorylation site [posttranslational modification]
1124991006668	intermolecular recognition site; other site
1124991006669	dimerization interface [polypeptide binding]; other site
1124991006670	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991006671	DNA binding site [nucleotide binding]
1124991006672	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1124991006673	HAMP domain; Region: HAMP; pfam00672
1124991006674	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991006675	dimer interface [polypeptide binding]; other site
1124991006676	phosphorylation site [posttranslational modification]
1124991006677	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991006678	ATP binding site [chemical binding]; other site
1124991006679	Mg2+ binding site [ion binding]; other site
1124991006680	G-X-G motif; other site
1124991006681	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1124991006682	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1124991006683	Moco binding site; other site
1124991006684	metal coordination site [ion binding]; other site
1124991006685	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1124991006686	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1124991006687	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1124991006688	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1124991006689	putative active site; other site
1124991006690	catalytic residue [active]
1124991006691	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1124991006692	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1124991006693	ligand binding site [chemical binding]; other site
1124991006694	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991006695	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991006696	TM-ABC transporter signature motif; other site
1124991006697	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991006698	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991006699	TM-ABC transporter signature motif; other site
1124991006700	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1124991006701	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1124991006702	Walker A/P-loop; other site
1124991006703	ATP binding site [chemical binding]; other site
1124991006704	Q-loop/lid; other site
1124991006705	ABC transporter signature motif; other site
1124991006706	Walker B; other site
1124991006707	D-loop; other site
1124991006708	H-loop/switch region; other site
1124991006709	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1124991006710	transcriptional regulator LsrR; Provisional; Region: PRK15418
1124991006711	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1124991006712	non-specific DNA interactions [nucleotide binding]; other site
1124991006713	DNA binding site [nucleotide binding]
1124991006714	sequence specific DNA binding site [nucleotide binding]; other site
1124991006715	putative cAMP binding site [chemical binding]; other site
1124991006716	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1124991006717	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1124991006718	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1124991006719	putative N- and C-terminal domain interface [polypeptide binding]; other site
1124991006720	putative active site [active]
1124991006721	putative MgATP binding site [chemical binding]; other site
1124991006722	catalytic site [active]
1124991006723	metal binding site [ion binding]; metal-binding site
1124991006724	putative carbohydrate binding site [chemical binding]; other site
1124991006725	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991006726	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1124991006727	homotrimer interaction site [polypeptide binding]; other site
1124991006728	putative active site [active]
1124991006729	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1124991006730	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1124991006731	ATP binding site [chemical binding]; other site
1124991006732	DEAD_2; Region: DEAD_2; pfam06733
1124991006733	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1124991006734	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1124991006735	Glycoprotease family; Region: Peptidase_M22; pfam00814
1124991006736	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1124991006737	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1124991006738	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1124991006739	acyl-activating enzyme (AAE) consensus motif; other site
1124991006740	putative AMP binding site [chemical binding]; other site
1124991006741	putative active site [active]
1124991006742	putative CoA binding site [chemical binding]; other site
1124991006743	ribonuclease D; Provisional; Region: PRK10829
1124991006744	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1124991006745	catalytic site [active]
1124991006746	putative active site [active]
1124991006747	putative substrate binding site [chemical binding]; other site
1124991006748	HRDC domain; Region: HRDC; pfam00570
1124991006749	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1124991006750	cell division inhibitor MinD; Provisional; Region: PRK10818
1124991006751	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1124991006752	Switch I; other site
1124991006753	Switch II; other site
1124991006754	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1124991006755	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1124991006756	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1124991006757	YcgL domain; Region: YcgL; pfam05166
1124991006758	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1124991006759	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1124991006760	hypothetical protein; Provisional; Region: PRK10691
1124991006761	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1124991006762	hypothetical protein; Provisional; Region: PRK05170
1124991006763	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1124991006764	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991006765	S-adenosylmethionine binding site [chemical binding]; other site
1124991006766	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1124991006767	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1124991006768	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991006769	Walker A/P-loop; other site
1124991006770	ATP binding site [chemical binding]; other site
1124991006771	Q-loop/lid; other site
1124991006772	ABC transporter signature motif; other site
1124991006773	Walker B; other site
1124991006774	D-loop; other site
1124991006775	H-loop/switch region; other site
1124991006776	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991006777	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1124991006778	dimer interface [polypeptide binding]; other site
1124991006779	putative PBP binding regions; other site
1124991006780	ABC-ATPase subunit  interface; other site
1124991006781	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
1124991006782	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991006783	intersubunit interface [polypeptide binding]; other site
1124991006784	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1124991006785	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1124991006786	ligand binding site [chemical binding]; other site
1124991006787	flexible hinge region; other site
1124991006788	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1124991006789	putative switch regulator; other site
1124991006790	non-specific DNA interactions [nucleotide binding]; other site
1124991006791	DNA binding site [nucleotide binding]
1124991006792	sequence specific DNA binding site [nucleotide binding]; other site
1124991006793	putative cAMP binding site [chemical binding]; other site
1124991006794	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1124991006795	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991006796	N-terminal plug; other site
1124991006797	ligand-binding site [chemical binding]; other site
1124991006798	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1124991006799	GAF domain; Region: GAF; pfam01590
1124991006800	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991006801	Walker A motif; other site
1124991006802	ATP binding site [chemical binding]; other site
1124991006803	Walker B motif; other site
1124991006804	arginine finger; other site
1124991006805	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1124991006806	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1124991006807	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1124991006808	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1124991006809	iron binding site [ion binding]; other site
1124991006810	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1124991006811	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991006812	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991006813	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1124991006814	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1124991006815	Hemerythrin-like domain; Region: Hr-like; cd12108
1124991006816	Fe binding site [ion binding]; other site
1124991006817	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1124991006818	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1124991006819	putative ligand binding site [chemical binding]; other site
1124991006820	putative NAD binding site [chemical binding]; other site
1124991006821	catalytic site [active]
1124991006822	Dicarboxylate transport; Region: DctA-YdbH; cl14674
1124991006823	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1124991006824	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
1124991006825	azoreductase; Reviewed; Region: PRK00170
1124991006826	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1124991006827	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1124991006828	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991006829	ATP binding site [chemical binding]; other site
1124991006830	putative Mg++ binding site [ion binding]; other site
1124991006831	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991006832	nucleotide binding region [chemical binding]; other site
1124991006833	ATP-binding site [chemical binding]; other site
1124991006834	Helicase associated domain (HA2); Region: HA2; pfam04408
1124991006835	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1124991006836	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1124991006837	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
1124991006838	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1124991006839	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1124991006840	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1124991006841	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1124991006842	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1124991006843	ligand binding site [chemical binding]; other site
1124991006844	homodimer interface [polypeptide binding]; other site
1124991006845	NAD(P) binding site [chemical binding]; other site
1124991006846	trimer interface B [polypeptide binding]; other site
1124991006847	trimer interface A [polypeptide binding]; other site
1124991006848	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1124991006849	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1124991006850	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1124991006851	universal stress protein UspE; Provisional; Region: PRK11175
1124991006852	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991006853	Ligand Binding Site [chemical binding]; other site
1124991006854	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991006855	Ligand Binding Site [chemical binding]; other site
1124991006856	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1124991006857	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1124991006858	ligand binding site [chemical binding]; other site
1124991006859	flexible hinge region; other site
1124991006860	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1124991006861	putative switch regulator; other site
1124991006862	non-specific DNA interactions [nucleotide binding]; other site
1124991006863	DNA binding site [nucleotide binding]
1124991006864	sequence specific DNA binding site [nucleotide binding]; other site
1124991006865	putative cAMP binding site [chemical binding]; other site
1124991006866	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
1124991006867	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
1124991006868	NAD(P) binding site [chemical binding]; other site
1124991006869	Predicted transcriptional regulators [Transcription]; Region: COG1695
1124991006870	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1124991006871	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1124991006872	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991006873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991006874	homodimer interface [polypeptide binding]; other site
1124991006875	catalytic residue [active]
1124991006876	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1124991006877	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1124991006878	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1124991006879	active site turn [active]
1124991006880	phosphorylation site [posttranslational modification]
1124991006881	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1124991006882	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991006883	DNA binding site [nucleotide binding]
1124991006884	domain linker motif; other site
1124991006885	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1124991006886	Predicted permeases [General function prediction only]; Region: COG0679
1124991006887	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
1124991006888	nudix motif; other site
1124991006889	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1124991006890	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1124991006891	homotetramer interface [polypeptide binding]; other site
1124991006892	ligand binding site [chemical binding]; other site
1124991006893	catalytic site [active]
1124991006894	NAD binding site [chemical binding]; other site
1124991006895	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1124991006896	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1124991006897	ligand binding site [chemical binding]; other site
1124991006898	flexible hinge region; other site
1124991006899	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1124991006900	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1124991006901	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1124991006902	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991006903	catalytic residue [active]
1124991006904	HEXXH motif domain; Region: mod_HExxH; TIGR04267
1124991006905	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1124991006906	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1124991006907	EamA-like transporter family; Region: EamA; pfam00892
1124991006908	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1124991006909	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991006910	DNA-binding site [nucleotide binding]; DNA binding site
1124991006911	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991006912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991006913	homodimer interface [polypeptide binding]; other site
1124991006914	catalytic residue [active]
1124991006915	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991006916	Coenzyme A binding pocket [chemical binding]; other site
1124991006917	magnesium-transporting ATPase; Provisional; Region: PRK15122
1124991006918	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1124991006919	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1124991006920	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1124991006921	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1124991006922	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1124991006923	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1124991006924	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1124991006925	Cupin-like domain; Region: Cupin_8; pfam13621
1124991006926	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1124991006927	Rhodanese-like domain; Region: Rhodanese; pfam00581
1124991006928	active site residue [active]
1124991006929	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1124991006930	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1124991006931	active site residue [active]
1124991006932	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1124991006933	active site residue [active]
1124991006934	putative inner membrane protein; Provisional; Region: PRK11099
1124991006935	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1124991006936	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991006937	N-terminal plug; other site
1124991006938	ligand-binding site [chemical binding]; other site
1124991006939	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
1124991006940	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991006941	intersubunit interface [polypeptide binding]; other site
1124991006942	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1124991006943	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991006944	ABC-ATPase subunit  interface; other site
1124991006945	dimer interface [polypeptide binding]; other site
1124991006946	putative PBP binding regions; other site
1124991006947	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1124991006948	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991006949	Walker A/P-loop; other site
1124991006950	ATP binding site [chemical binding]; other site
1124991006951	Q-loop/lid; other site
1124991006952	ABC transporter signature motif; other site
1124991006953	Walker B; other site
1124991006954	D-loop; other site
1124991006955	H-loop/switch region; other site
1124991006956	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1124991006957	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1124991006958	FMN binding site [chemical binding]; other site
1124991006959	active site
1124991006960	substrate binding site [chemical binding]; other site
1124991006961	catalytic residue [active]
1124991006962	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991006963	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991006964	putative chaperone; Provisional; Region: PRK11678
1124991006965	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1124991006966	nucleotide binding site [chemical binding]; other site
1124991006967	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1124991006968	SBD interface [polypeptide binding]; other site
1124991006969	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
1124991006970	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991006971	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1124991006972	N-ethylammeline chlorohydrolase; Provisional; Region: PRK09045
1124991006973	active site
1124991006974	putative substrate binding pocket [chemical binding]; other site
1124991006975	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1124991006976	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1124991006977	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1124991006978	Rhomboid family; Region: Rhomboid; cl11446
1124991006979	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1124991006980	LysE type translocator; Region: LysE; cl00565
1124991006981	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1124991006982	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991006983	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991006984	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1124991006985	Protein export membrane protein; Region: SecD_SecF; cl14618
1124991006986	Protein export membrane protein; Region: SecD_SecF; cl14618
1124991006987	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_3; cd06151
1124991006988	homotrimer interaction site [polypeptide binding]; other site
1124991006989	putative active site [active]
1124991006990	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1124991006991	hypothetical protein; Validated; Region: PRK00124
1124991006992	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cl16915
1124991006993	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1124991006994	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991006995	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991006996	Walker A/P-loop; other site
1124991006997	ATP binding site [chemical binding]; other site
1124991006998	Q-loop/lid; other site
1124991006999	ABC transporter signature motif; other site
1124991007000	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007001	Walker B; other site
1124991007002	ABC transporter; Region: ABC_tran_2; pfam12848
1124991007003	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007004	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1124991007005	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991007006	dimerization interface [polypeptide binding]; other site
1124991007007	putative DNA binding site [nucleotide binding]; other site
1124991007008	putative Zn2+ binding site [ion binding]; other site
1124991007009	AsnC family; Region: AsnC_trans_reg; pfam01037
1124991007010	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1124991007011	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991007012	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991007013	AAA domain; Region: AAA_33; pfam13671
1124991007014	AAA domain; Region: AAA_17; pfam13207
1124991007015	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1124991007016	EamA-like transporter family; Region: EamA; pfam00892
1124991007017	EamA-like transporter family; Region: EamA; pfam00892
1124991007018	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1124991007019	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1124991007020	Domain of unknown function (DUF4274); Region: DUF4274; pfam14096
1124991007021	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1124991007022	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1124991007023	dimer interface [polypeptide binding]; other site
1124991007024	ADP-ribose binding site [chemical binding]; other site
1124991007025	active site
1124991007026	nudix motif; other site
1124991007027	metal binding site [ion binding]; metal-binding site
1124991007028	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991007029	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991007030	Coenzyme A binding pocket [chemical binding]; other site
1124991007031	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991007032	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007033	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991007034	putative effector binding pocket; other site
1124991007035	dimerization interface [polypeptide binding]; other site
1124991007036	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991007037	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1124991007038	cystathionine beta-lyase; Provisional; Region: PRK05967
1124991007039	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1124991007040	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991007041	catalytic residue [active]
1124991007042	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1124991007043	active site
1124991007044	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1124991007045	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1124991007046	putative ligand binding residues [chemical binding]; other site
1124991007047	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1124991007048	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991007049	N-terminal plug; other site
1124991007050	ligand-binding site [chemical binding]; other site
1124991007051	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1124991007052	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007053	putative substrate translocation pore; other site
1124991007054	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1124991007055	nucleoside/Zn binding site; other site
1124991007056	dimer interface [polypeptide binding]; other site
1124991007057	catalytic motif [active]
1124991007058	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991007059	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007060	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991007061	putative effector binding pocket; other site
1124991007062	dimerization interface [polypeptide binding]; other site
1124991007063	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1124991007064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007065	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1124991007066	dimer interface [polypeptide binding]; other site
1124991007067	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1124991007068	metal binding site [ion binding]; metal-binding site
1124991007069	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1124991007070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007071	putative substrate translocation pore; other site
1124991007072	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991007073	salt bridge; other site
1124991007074	non-specific DNA binding site [nucleotide binding]; other site
1124991007075	sequence-specific DNA binding site [nucleotide binding]; other site
1124991007076	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1124991007077	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
1124991007078	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007079	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1124991007080	putative substrate translocation pore; other site
1124991007081	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991007082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007083	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991007084	dimerization interface [polypeptide binding]; other site
1124991007085	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1124991007086	Beta-lactamase; Region: Beta-lactamase; pfam00144
1124991007087	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1124991007088	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1124991007089	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1124991007090	conserved cys residue [active]
1124991007091	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991007092	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991007093	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1124991007094	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1124991007095	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991007096	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007097	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1124991007098	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007099	putative substrate translocation pore; other site
1124991007100	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
1124991007101	nudix motif; other site
1124991007102	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1124991007103	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991007104	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1124991007105	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991007106	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1124991007107	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1124991007108	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1124991007109	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1124991007110	intersubunit interface [polypeptide binding]; other site
1124991007111	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1124991007112	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991007113	Walker A/P-loop; other site
1124991007114	ATP binding site [chemical binding]; other site
1124991007115	Q-loop/lid; other site
1124991007116	ABC transporter signature motif; other site
1124991007117	Walker B; other site
1124991007118	D-loop; other site
1124991007119	H-loop/switch region; other site
1124991007120	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1124991007121	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991007122	ABC-ATPase subunit  interface; other site
1124991007123	dimer interface [polypeptide binding]; other site
1124991007124	putative PBP binding regions; other site
1124991007125	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1124991007126	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1124991007127	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1124991007128	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg6; cd04781
1124991007129	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1124991007130	DNA binding residues [nucleotide binding]
1124991007131	putative dimer interface [polypeptide binding]; other site
1124991007132	putative metal binding residues [ion binding]; other site
1124991007133	putative transporter; Provisional; Region: PRK03699
1124991007134	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
1124991007135	Asp-box motif; other site
1124991007136	catalytic site [active]
1124991007137	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991007138	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991007139	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991007140	Coenzyme A binding pocket [chemical binding]; other site
1124991007141	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991007142	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991007143	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1124991007144	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991007145	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991007146	Coenzyme A binding pocket [chemical binding]; other site
1124991007147	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1124991007148	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991007149	Coenzyme A binding pocket [chemical binding]; other site
1124991007150	Salmonella virulence-associated 28kDa protein; Region: VRP3; cl04142
1124991007151	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1124991007152	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007153	ABC transporter; Region: ABC_tran_2; pfam12848
1124991007154	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007155	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1124991007156	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1124991007157	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1124991007158	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991007159	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1124991007160	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1124991007161	DNA binding site [nucleotide binding]
1124991007162	active site
1124991007163	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1124991007164	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1124991007165	Propionate catabolism activator; Region: PrpR_N; pfam06506
1124991007166	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991007167	Walker A motif; other site
1124991007168	ATP binding site [chemical binding]; other site
1124991007169	Walker B motif; other site
1124991007170	arginine finger; other site
1124991007171	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1124991007172	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1124991007173	tetramer interface [polypeptide binding]; other site
1124991007174	active site
1124991007175	Mg2+/Mn2+ binding site [ion binding]; other site
1124991007176	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1124991007177	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1124991007178	oxalacetate binding site [chemical binding]; other site
1124991007179	citrylCoA binding site [chemical binding]; other site
1124991007180	coenzyme A binding site [chemical binding]; other site
1124991007181	catalytic triad [active]
1124991007182	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1124991007183	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1124991007184	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1124991007185	malonic semialdehyde reductase; Provisional; Region: PRK10538
1124991007186	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1124991007187	putative NAD(P) binding site [chemical binding]; other site
1124991007188	homodimer interface [polypeptide binding]; other site
1124991007189	homotetramer interface [polypeptide binding]; other site
1124991007190	active site
1124991007191	hypothetical protein; Provisional; Region: PRK13659
1124991007192	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1124991007193	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1124991007194	AAA domain; Region: AAA_26; pfam13500
1124991007195	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1124991007196	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991007197	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1124991007198	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1124991007199	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1124991007200	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007201	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1124991007202	dimerization interface [polypeptide binding]; other site
1124991007203	substrate binding pocket [chemical binding]; other site
1124991007204	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1124991007205	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007206	putative substrate translocation pore; other site
1124991007207	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1124991007208	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1124991007209	Class II fumarases; Region: Fumarase_classII; cd01362
1124991007210	active site
1124991007211	tetramer interface [polypeptide binding]; other site
1124991007212	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1124991007213	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1124991007214	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1124991007215	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1124991007216	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1124991007217	adenosine deaminase; Provisional; Region: PRK09358
1124991007218	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1124991007219	active site
1124991007220	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1124991007221	Repair protein; Region: Repair_PSII; pfam04536
1124991007222	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1124991007223	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1124991007224	putative oxidoreductase; Provisional; Region: PRK11579
1124991007225	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1124991007226	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1124991007227	ERp29 and ERp38, C-terminal domain; composed of the protein disulfide isomerase (PDI)-like proteins ERp29 and ERp38. ERp29 (also called ERp28) is a ubiquitous endoplasmic reticulum (ER)-resident protein expressed in high levels in secretory cells. It...; Region: ERp29c; cl02782
1124991007228	electron transport complex protein RsxA; Provisional; Region: PRK05151
1124991007229	electron transport complex protein RnfB; Provisional; Region: PRK05113
1124991007230	Putative Fe-S cluster; Region: FeS; cl17515
1124991007231	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991007232	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1124991007233	SLBB domain; Region: SLBB; pfam10531
1124991007234	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1124991007235	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1124991007236	electron transport complex protein RnfG; Validated; Region: PRK01908
1124991007237	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1124991007238	endonuclease III; Provisional; Region: PRK10702
1124991007239	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1124991007240	minor groove reading motif; other site
1124991007241	helix-hairpin-helix signature motif; other site
1124991007242	substrate binding pocket [chemical binding]; other site
1124991007243	active site
1124991007244	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1124991007245	exoribonuclease II; Provisional; Region: PRK05054
1124991007246	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1124991007247	RNB domain; Region: RNB; pfam00773
1124991007248	S1 RNA binding domain; Region: S1; pfam00575
1124991007249	translation initiation factor Sui1; Validated; Region: PRK06824
1124991007250	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1124991007251	putative rRNA binding site [nucleotide binding]; other site
1124991007252	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1124991007253	active site
1124991007254	dimer interface [polypeptide binding]; other site
1124991007255	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1124991007256	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
1124991007257	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1124991007258	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1124991007259	active site
1124991007260	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1124991007261	dimerization interface [polypeptide binding]; other site
1124991007262	active site
1124991007263	aconitate hydratase; Validated; Region: PRK09277
1124991007264	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1124991007265	substrate binding site [chemical binding]; other site
1124991007266	ligand binding site [chemical binding]; other site
1124991007267	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1124991007268	substrate binding site [chemical binding]; other site
1124991007269	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1124991007270	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007271	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1124991007272	substrate binding site [chemical binding]; other site
1124991007273	dimerization interface [polypeptide binding]; other site
1124991007274	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1124991007275	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1124991007276	active site
1124991007277	interdomain interaction site; other site
1124991007278	putative metal-binding site [ion binding]; other site
1124991007279	nucleotide binding site [chemical binding]; other site
1124991007280	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1124991007281	domain I; other site
1124991007282	DNA binding groove [nucleotide binding]
1124991007283	phosphate binding site [ion binding]; other site
1124991007284	domain II; other site
1124991007285	domain III; other site
1124991007286	nucleotide binding site [chemical binding]; other site
1124991007287	catalytic site [active]
1124991007288	domain IV; other site
1124991007289	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1124991007290	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1124991007291	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1124991007292	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1124991007293	hypothetical protein; Provisional; Region: PRK11037
1124991007294	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1124991007295	putative inner membrane peptidase; Provisional; Region: PRK11778
1124991007296	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1124991007297	tandem repeat interface [polypeptide binding]; other site
1124991007298	oligomer interface [polypeptide binding]; other site
1124991007299	active site residues [active]
1124991007300	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1124991007301	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1124991007302	NAD(P) binding site [chemical binding]; other site
1124991007303	active site
1124991007304	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1124991007305	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991007306	RNA binding surface [nucleotide binding]; other site
1124991007307	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1124991007308	probable active site [active]
1124991007309	hypothetical protein; Provisional; Region: PRK11630
1124991007310	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1124991007311	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1124991007312	active site
1124991007313	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1124991007314	anthranilate synthase component I; Provisional; Region: PRK13564
1124991007315	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1124991007316	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1124991007317	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1124991007318	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1124991007319	glutamine binding [chemical binding]; other site
1124991007320	catalytic triad [active]
1124991007321	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1124991007322	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1124991007323	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1124991007324	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1124991007325	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1124991007326	active site
1124991007327	ribulose/triose binding site [chemical binding]; other site
1124991007328	phosphate binding site [ion binding]; other site
1124991007329	substrate (anthranilate) binding pocket [chemical binding]; other site
1124991007330	product (indole) binding pocket [chemical binding]; other site
1124991007331	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1124991007332	active site
1124991007333	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1124991007334	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1124991007335	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991007336	catalytic residue [active]
1124991007337	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1124991007338	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1124991007339	substrate binding site [chemical binding]; other site
1124991007340	active site
1124991007341	catalytic residues [active]
1124991007342	heterodimer interface [polypeptide binding]; other site
1124991007343	BON domain; Region: BON; pfam04972
1124991007344	outer membrane protein W; Provisional; Region: PRK10959
1124991007345	hypothetical protein; Provisional; Region: PRK02868
1124991007346	YcxB-like protein; Region: YcxB; pfam14317
1124991007347	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1124991007348	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1124991007349	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991007350	active site
1124991007351	phosphorylation site [posttranslational modification]
1124991007352	intermolecular recognition site; other site
1124991007353	dimerization interface [polypeptide binding]; other site
1124991007354	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991007355	DNA binding site [nucleotide binding]
1124991007356	sensor protein QseC; Provisional; Region: PRK10337
1124991007357	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991007358	dimer interface [polypeptide binding]; other site
1124991007359	phosphorylation site [posttranslational modification]
1124991007360	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991007361	ATP binding site [chemical binding]; other site
1124991007362	Mg2+ binding site [ion binding]; other site
1124991007363	G-X-G motif; other site
1124991007364	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1124991007365	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1124991007366	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1124991007367	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1124991007368	intracellular septation protein A; Reviewed; Region: PRK00259
1124991007369	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1124991007370	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1124991007371	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1124991007372	ATP binding site [chemical binding]; other site
1124991007373	Mg++ binding site [ion binding]; other site
1124991007374	motif III; other site
1124991007375	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991007376	nucleotide binding region [chemical binding]; other site
1124991007377	ATP-binding site [chemical binding]; other site
1124991007378	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1124991007379	putative RNA binding site [nucleotide binding]; other site
1124991007380	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1124991007381	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1124991007382	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1124991007383	putative active site [active]
1124991007384	catalytic site [active]
1124991007385	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1124991007386	putative active site [active]
1124991007387	catalytic site [active]
1124991007388	Protein of unknown function, DUF440; Region: DUF440; cl11472
1124991007389	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1124991007390	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007391	Walker A/P-loop; other site
1124991007392	ATP binding site [chemical binding]; other site
1124991007393	Q-loop/lid; other site
1124991007394	ABC transporter signature motif; other site
1124991007395	Walker B; other site
1124991007396	D-loop; other site
1124991007397	H-loop/switch region; other site
1124991007398	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1124991007399	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1124991007400	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007401	Walker A/P-loop; other site
1124991007402	ATP binding site [chemical binding]; other site
1124991007403	Q-loop/lid; other site
1124991007404	ABC transporter signature motif; other site
1124991007405	Walker B; other site
1124991007406	D-loop; other site
1124991007407	H-loop/switch region; other site
1124991007408	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1124991007409	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1124991007410	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1124991007411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007412	dimer interface [polypeptide binding]; other site
1124991007413	conserved gate region; other site
1124991007414	ABC-ATPase subunit interface; other site
1124991007415	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1124991007416	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007417	dimer interface [polypeptide binding]; other site
1124991007418	conserved gate region; other site
1124991007419	putative PBP binding loops; other site
1124991007420	ABC-ATPase subunit interface; other site
1124991007421	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1124991007422	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1124991007423	peptide binding site [polypeptide binding]; other site
1124991007424	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1124991007425	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1124991007426	peptide binding site [polypeptide binding]; other site
1124991007427	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1124991007428	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1124991007429	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1124991007430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007431	dimer interface [polypeptide binding]; other site
1124991007432	conserved gate region; other site
1124991007433	putative PBP binding loops; other site
1124991007434	ABC-ATPase subunit interface; other site
1124991007435	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1124991007436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007437	dimer interface [polypeptide binding]; other site
1124991007438	conserved gate region; other site
1124991007439	ABC-ATPase subunit interface; other site
1124991007440	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1124991007441	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007442	Walker A/P-loop; other site
1124991007443	ATP binding site [chemical binding]; other site
1124991007444	Q-loop/lid; other site
1124991007445	ABC transporter signature motif; other site
1124991007446	Walker B; other site
1124991007447	D-loop; other site
1124991007448	H-loop/switch region; other site
1124991007449	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1124991007450	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007451	Walker A/P-loop; other site
1124991007452	ATP binding site [chemical binding]; other site
1124991007453	Q-loop/lid; other site
1124991007454	ABC transporter signature motif; other site
1124991007455	Walker B; other site
1124991007456	D-loop; other site
1124991007457	H-loop/switch region; other site
1124991007458	hypothetical protein; Provisional; Region: PRK11111
1124991007459	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1124991007460	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1124991007461	putative catalytic cysteine [active]
1124991007462	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1124991007463	putative active site [active]
1124991007464	metal binding site [ion binding]; metal-binding site
1124991007465	thymidine kinase; Provisional; Region: PRK04296
1124991007466	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1124991007467	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1124991007468	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1124991007469	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1124991007470	putative NAD(P) binding site [chemical binding]; other site
1124991007471	active site
1124991007472	putative substrate binding site [chemical binding]; other site
1124991007473	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1124991007474	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1124991007475	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1124991007476	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1124991007477	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1124991007478	active site
1124991007479	tetramer interface; other site
1124991007480	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991007481	active site
1124991007482	response regulator of RpoS; Provisional; Region: PRK10693
1124991007483	phosphorylation site [posttranslational modification]
1124991007484	intermolecular recognition site; other site
1124991007485	dimerization interface [polypeptide binding]; other site
1124991007486	hypothetical protein; Provisional; Region: PRK01617
1124991007487	SEC-C motif; Region: SEC-C; pfam02810
1124991007488	SEC-C motif; Region: SEC-C; pfam02810
1124991007489	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1124991007490	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1124991007491	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1124991007492	putative active site [active]
1124991007493	putative substrate binding site [chemical binding]; other site
1124991007494	putative cosubstrate binding site; other site
1124991007495	catalytic site [active]
1124991007496	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991007497	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991007498	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991007499	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991007500	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007501	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1124991007502	putative catalytic site [active]
1124991007503	putative phosphate binding site [ion binding]; other site
1124991007504	active site
1124991007505	metal binding site A [ion binding]; metal-binding site
1124991007506	DNA binding site [nucleotide binding]
1124991007507	putative AP binding site [nucleotide binding]; other site
1124991007508	putative metal binding site B [ion binding]; other site
1124991007509	DNA topoisomerase III; Provisional; Region: PRK07726
1124991007510	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1124991007511	active site
1124991007512	putative interdomain interaction site [polypeptide binding]; other site
1124991007513	putative metal-binding site [ion binding]; other site
1124991007514	putative nucleotide binding site [chemical binding]; other site
1124991007515	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1124991007516	domain I; other site
1124991007517	DNA binding groove [nucleotide binding]
1124991007518	phosphate binding site [ion binding]; other site
1124991007519	domain II; other site
1124991007520	domain III; other site
1124991007521	nucleotide binding site [chemical binding]; other site
1124991007522	catalytic site [active]
1124991007523	domain IV; other site
1124991007524	selenophosphate synthetase; Provisional; Region: PRK00943
1124991007525	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1124991007526	dimerization interface [polypeptide binding]; other site
1124991007527	putative ATP binding site [chemical binding]; other site
1124991007528	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1124991007529	putative FMN binding site [chemical binding]; other site
1124991007530	protease 4; Provisional; Region: PRK10949
1124991007531	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1124991007532	tandem repeat interface [polypeptide binding]; other site
1124991007533	oligomer interface [polypeptide binding]; other site
1124991007534	active site residues [active]
1124991007535	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1124991007536	tandem repeat interface [polypeptide binding]; other site
1124991007537	oligomer interface [polypeptide binding]; other site
1124991007538	active site residues [active]
1124991007539	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1124991007540	active site
1124991007541	homodimer interface [polypeptide binding]; other site
1124991007542	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1124991007543	Isochorismatase family; Region: Isochorismatase; pfam00857
1124991007544	catalytic triad [active]
1124991007545	metal binding site [ion binding]; metal-binding site
1124991007546	conserved cis-peptide bond; other site
1124991007547	Protein of unknown function (DUF1315); Region: DUF1315; pfam07023
1124991007548	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1124991007549	SelR domain; Region: SelR; pfam01641
1124991007550	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1124991007551	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1124991007552	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1124991007553	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1124991007554	active site
1124991007555	phosphate binding residues; other site
1124991007556	catalytic residues [active]
1124991007557	hypothetical protein; Provisional; Region: PRK10030
1124991007558	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1124991007559	Acylphosphatase; Region: Acylphosphatase; pfam00708
1124991007560	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1124991007561	HypF finger; Region: zf-HYPF; pfam07503
1124991007562	HypF finger; Region: zf-HYPF; pfam07503
1124991007563	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1124991007564	alanine racemase; Reviewed; Region: dadX; PRK03646
1124991007565	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1124991007566	active site
1124991007567	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1124991007568	substrate binding site [chemical binding]; other site
1124991007569	catalytic residues [active]
1124991007570	dimer interface [polypeptide binding]; other site
1124991007571	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1124991007572	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1124991007573	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1124991007574	fatty acid metabolism regulator; Provisional; Region: PRK04984
1124991007575	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991007576	DNA-binding site [nucleotide binding]; DNA binding site
1124991007577	FadR C-terminal domain; Region: FadR_C; pfam07840
1124991007578	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1124991007579	disulfide bond formation protein B; Provisional; Region: PRK01749
1124991007580	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1124991007581	putative arabinose transporter; Provisional; Region: PRK03545
1124991007582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007583	putative substrate translocation pore; other site
1124991007584	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1124991007585	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991007586	Walker A/P-loop; other site
1124991007587	ATP binding site [chemical binding]; other site
1124991007588	Q-loop/lid; other site
1124991007589	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007590	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1124991007591	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1124991007592	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
1124991007593	putative active site [active]
1124991007594	putative metal binding residues [ion binding]; other site
1124991007595	signature motif; other site
1124991007596	putative triphosphate binding site [ion binding]; other site
1124991007597	dimer interface [polypeptide binding]; other site
1124991007598	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1124991007599	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1124991007600	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1124991007601	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991007602	non-specific DNA binding site [nucleotide binding]; other site
1124991007603	salt bridge; other site
1124991007604	sequence-specific DNA binding site [nucleotide binding]; other site
1124991007605	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1124991007606	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1124991007607	Ligand Binding Site [chemical binding]; other site
1124991007608	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1124991007609	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1124991007610	Cl binding site [ion binding]; other site
1124991007611	oligomer interface [polypeptide binding]; other site
1124991007612	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1124991007613	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1124991007614	peptide binding site [polypeptide binding]; other site
1124991007615	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1124991007616	dimer interface [polypeptide binding]; other site
1124991007617	catalytic triad [active]
1124991007618	peroxidatic and resolving cysteines [active]
1124991007619	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1124991007620	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1124991007621	putative aromatic amino acid binding site; other site
1124991007622	PAS domain; Region: PAS; smart00091
1124991007623	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991007624	Walker A motif; other site
1124991007625	ATP binding site [chemical binding]; other site
1124991007626	Walker B motif; other site
1124991007627	arginine finger; other site
1124991007628	hypothetical protein; Provisional; Region: PRK05415
1124991007629	Domain of unknown function (DUF697); Region: DUF697; cl12064
1124991007630	Predicted ATPase [General function prediction only]; Region: COG3106
1124991007631	Phage shock protein PspD (Phageshock_PspD); Region: Phageshock_PspD; cl11512
1124991007632	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1124991007633	phage shock protein C; Region: phageshock_pspC; TIGR02978
1124991007634	phage shock protein B; Provisional; Region: pspB; PRK09458
1124991007635	phage shock protein PspA; Provisional; Region: PRK10698
1124991007636	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1124991007637	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991007638	Walker A motif; other site
1124991007639	ATP binding site [chemical binding]; other site
1124991007640	Walker B motif; other site
1124991007641	arginine finger; other site
1124991007642	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1124991007643	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1124991007644	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1124991007645	peptide binding site [polypeptide binding]; other site
1124991007646	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1124991007647	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007648	putative PBP binding loops; other site
1124991007649	dimer interface [polypeptide binding]; other site
1124991007650	ABC-ATPase subunit interface; other site
1124991007651	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1124991007652	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1124991007653	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991007654	putative PBP binding loops; other site
1124991007655	dimer interface [polypeptide binding]; other site
1124991007656	ABC-ATPase subunit interface; other site
1124991007657	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1124991007658	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007659	Walker A/P-loop; other site
1124991007660	ATP binding site [chemical binding]; other site
1124991007661	Q-loop/lid; other site
1124991007662	ABC transporter signature motif; other site
1124991007663	Walker B; other site
1124991007664	D-loop; other site
1124991007665	H-loop/switch region; other site
1124991007666	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1124991007667	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1124991007668	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991007669	Walker A/P-loop; other site
1124991007670	ATP binding site [chemical binding]; other site
1124991007671	Q-loop/lid; other site
1124991007672	ABC transporter signature motif; other site
1124991007673	Walker B; other site
1124991007674	D-loop; other site
1124991007675	H-loop/switch region; other site
1124991007676	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1124991007677	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1124991007678	NAD binding site [chemical binding]; other site
1124991007679	homotetramer interface [polypeptide binding]; other site
1124991007680	homodimer interface [polypeptide binding]; other site
1124991007681	substrate binding site [chemical binding]; other site
1124991007682	active site
1124991007683	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1124991007684	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1124991007685	glutathionine S-transferase; Provisional; Region: PRK10542
1124991007686	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1124991007687	C-terminal domain interface [polypeptide binding]; other site
1124991007688	GSH binding site (G-site) [chemical binding]; other site
1124991007689	dimer interface [polypeptide binding]; other site
1124991007690	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1124991007691	dimer interface [polypeptide binding]; other site
1124991007692	N-terminal domain interface [polypeptide binding]; other site
1124991007693	substrate binding pocket (H-site) [chemical binding]; other site
1124991007694	pyridoxamine kinase; Validated; Region: PRK05756
1124991007695	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1124991007696	dimer interface [polypeptide binding]; other site
1124991007697	pyridoxal binding site [chemical binding]; other site
1124991007698	ATP binding site [chemical binding]; other site
1124991007699	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1124991007700	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1124991007701	active site
1124991007702	HIGH motif; other site
1124991007703	dimer interface [polypeptide binding]; other site
1124991007704	KMSKS motif; other site
1124991007705	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991007706	RNA binding surface [nucleotide binding]; other site
1124991007707	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1124991007708	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1124991007709	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1124991007710	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1124991007711	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1124991007712	transcriptional regulator SlyA; Provisional; Region: PRK03573
1124991007713	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1124991007714	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1124991007715	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1124991007716	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1124991007717	dimer interface [polypeptide binding]; other site
1124991007718	active site
1124991007719	metal binding site [ion binding]; metal-binding site
1124991007720	glutathione binding site [chemical binding]; other site
1124991007721	ribonuclease T; Provisional; Region: PRK05168
1124991007722	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1124991007723	active site
1124991007724	catalytic site [active]
1124991007725	substrate binding site [chemical binding]; other site
1124991007726	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cl11615
1124991007727	switch II binding region; other site
1124991007728	Rac1 P-loop interaction site [polypeptide binding]; other site
1124991007729	GTP binding residues [chemical binding]; other site
1124991007730	switch I binding region; other site
1124991007731	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1124991007732	putative GSH binding site [chemical binding]; other site
1124991007733	catalytic residues [active]
1124991007734	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1124991007735	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1124991007736	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1124991007737	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1124991007738	active site
1124991007739	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1124991007740	superoxide dismutase; Provisional; Region: PRK10543
1124991007741	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1124991007742	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1124991007743	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1124991007744	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991007745	DNA binding site [nucleotide binding]
1124991007746	domain linker motif; other site
1124991007747	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1124991007748	dimerization interface [polypeptide binding]; other site
1124991007749	ligand binding site [chemical binding]; other site
1124991007750	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1124991007751	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991007752	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991007753	dimerization interface [polypeptide binding]; other site
1124991007754	putative transporter; Provisional; Region: PRK11043
1124991007755	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991007756	putative substrate translocation pore; other site
1124991007757	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1124991007758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991007759	S-adenosylmethionine binding site [chemical binding]; other site
1124991007760	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1124991007761	Lumazine binding domain; Region: Lum_binding; pfam00677
1124991007762	Lumazine binding domain; Region: Lum_binding; pfam00677
1124991007763	multidrug efflux protein; Reviewed; Region: PRK01766
1124991007764	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1124991007765	cation binding site [ion binding]; other site
1124991007766	pyruvate kinase; Provisional; Region: PRK09206
1124991007767	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1124991007768	domain interfaces; other site
1124991007769	active site
1124991007770	Murein lipoprotein [Cell envelope biogenesis, outer membrane]; Region: COG4238; cl11539
1124991007771	L,D-transpeptidase; Provisional; Region: PRK10260
1124991007772	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1124991007773	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1124991007774	Fe-S metabolism associated domain; Region: SufE; cl00951
1124991007775	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1124991007776	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1124991007777	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991007778	catalytic residue [active]
1124991007779	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1124991007780	FeS assembly protein SufD; Region: sufD; TIGR01981
1124991007781	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1124991007782	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1124991007783	Walker A/P-loop; other site
1124991007784	ATP binding site [chemical binding]; other site
1124991007785	Q-loop/lid; other site
1124991007786	ABC transporter signature motif; other site
1124991007787	Walker B; other site
1124991007788	D-loop; other site
1124991007789	H-loop/switch region; other site
1124991007790	putative ABC transporter; Region: ycf24; CHL00085
1124991007791	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1124991007792	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1124991007793	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1124991007794	CoenzymeA binding site [chemical binding]; other site
1124991007795	subunit interaction site [polypeptide binding]; other site
1124991007796	PHB binding site; other site
1124991007797	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1124991007798	FAD binding domain; Region: FAD_binding_4; pfam01565
1124991007799	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1124991007800	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1124991007801	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1124991007802	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1124991007803	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1124991007804	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1124991007805	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1124991007806	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1124991007807	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1124991007808	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1124991007809	Hemin uptake protein hemP; Region: hemP; pfam10636
1124991007810	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
1124991007811	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1124991007812	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1124991007813	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
1124991007814	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1124991007815	putative hemin binding site; other site
1124991007816	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1124991007817	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991007818	ABC-ATPase subunit  interface; other site
1124991007819	dimer interface [polypeptide binding]; other site
1124991007820	putative PBP binding regions; other site
1124991007821	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
1124991007822	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991007823	Walker A/P-loop; other site
1124991007824	ATP binding site [chemical binding]; other site
1124991007825	Q-loop/lid; other site
1124991007826	ABC transporter signature motif; other site
1124991007827	Walker B; other site
1124991007828	D-loop; other site
1124991007829	H-loop/switch region; other site
1124991007830	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1124991007831	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991007832	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1124991007833	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1124991007834	E-class dimer interface [polypeptide binding]; other site
1124991007835	P-class dimer interface [polypeptide binding]; other site
1124991007836	active site
1124991007837	Cu2+ binding site [ion binding]; other site
1124991007838	Zn2+ binding site [ion binding]; other site
1124991007839	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1124991007840	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1124991007841	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1124991007842	NlpC/P60 family; Region: NLPC_P60; pfam00877
1124991007843	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1124991007844	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1124991007845	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1124991007846	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1124991007847	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1124991007848	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1124991007849	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1124991007850	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1124991007851	putative active site [active]
1124991007852	putative catalytic site [active]
1124991007853	putative Zn binding site [ion binding]; other site
1124991007854	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1124991007855	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1124991007856	active site
1124991007857	substrate binding site [chemical binding]; other site
1124991007858	cosubstrate binding site; other site
1124991007859	catalytic site [active]
1124991007860	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1124991007861	active site
1124991007862	hexamer interface [polypeptide binding]; other site
1124991007863	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1124991007864	NAD binding site [chemical binding]; other site
1124991007865	substrate binding site [chemical binding]; other site
1124991007866	active site
1124991007867	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1124991007868	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1124991007869	Ligand binding site; other site
1124991007870	Putative Catalytic site; other site
1124991007871	DXD motif; other site
1124991007872	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1124991007873	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1124991007874	inhibitor-cofactor binding pocket; inhibition site
1124991007875	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991007876	catalytic residue [active]
1124991007877	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1124991007878	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991007879	Walker A/P-loop; other site
1124991007880	ATP binding site [chemical binding]; other site
1124991007881	Q-loop/lid; other site
1124991007882	ABC transporter signature motif; other site
1124991007883	Walker B; other site
1124991007884	D-loop; other site
1124991007885	H-loop/switch region; other site
1124991007886	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1124991007887	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991007888	ABC-ATPase subunit  interface; other site
1124991007889	dimer interface [polypeptide binding]; other site
1124991007890	putative PBP binding regions; other site
1124991007891	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1124991007892	IHF dimer interface [polypeptide binding]; other site
1124991007893	IHF - DNA interface [nucleotide binding]; other site
1124991007894	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1124991007895	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1124991007896	putative tRNA-binding site [nucleotide binding]; other site
1124991007897	B3/4 domain; Region: B3_4; pfam03483
1124991007898	tRNA synthetase B5 domain; Region: B5; smart00874
1124991007899	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1124991007900	dimer interface [polypeptide binding]; other site
1124991007901	motif 1; other site
1124991007902	motif 3; other site
1124991007903	motif 2; other site
1124991007904	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1124991007905	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1124991007906	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1124991007907	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1124991007908	dimer interface [polypeptide binding]; other site
1124991007909	motif 1; other site
1124991007910	active site
1124991007911	motif 2; other site
1124991007912	motif 3; other site
1124991007913	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1124991007914	23S rRNA binding site [nucleotide binding]; other site
1124991007915	L21 binding site [polypeptide binding]; other site
1124991007916	L13 binding site [polypeptide binding]; other site
1124991007917	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1124991007918	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1124991007919	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1124991007920	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1124991007921	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1124991007922	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1124991007923	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1124991007924	active site
1124991007925	dimer interface [polypeptide binding]; other site
1124991007926	motif 1; other site
1124991007927	motif 2; other site
1124991007928	motif 3; other site
1124991007929	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1124991007930	anticodon binding site; other site
1124991007931	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1124991007932	Sulfatase; Region: Sulfatase; cl17466
1124991007933	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1124991007934	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1124991007935	catalytic residue [active]
1124991007936	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1124991007937	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1124991007938	metal binding site [ion binding]; metal-binding site
1124991007939	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1124991007940	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1124991007941	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1124991007942	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991007943	ABC-ATPase subunit  interface; other site
1124991007944	dimer interface [polypeptide binding]; other site
1124991007945	putative PBP binding regions; other site
1124991007946	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1124991007947	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991007948	ABC-ATPase subunit  interface; other site
1124991007949	dimer interface [polypeptide binding]; other site
1124991007950	putative PBP binding regions; other site
1124991007951	Fructosamine kinase; Region: Fructosamin_kin; pfam03881
1124991007952	Phosphotransferase enzyme family; Region: APH; pfam01636
1124991007953	YniB-like protein; Region: YniB; pfam14002
1124991007954	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1124991007955	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991007956	motif II; other site
1124991007957	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; cl00868
1124991007958	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1124991007959	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1124991007960	heat shock protein HtpX; Provisional; Region: PRK05457
1124991007961	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1124991007962	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1124991007963	putative metal binding site [ion binding]; other site
1124991007964	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1124991007965	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1124991007966	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1124991007967	putative NAD(P) binding site [chemical binding]; other site
1124991007968	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1124991007969	transcriptional regulator NarP; Provisional; Region: PRK10403
1124991007970	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991007971	active site
1124991007972	phosphorylation site [posttranslational modification]
1124991007973	intermolecular recognition site; other site
1124991007974	dimerization interface [polypeptide binding]; other site
1124991007975	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991007976	DNA binding residues [nucleotide binding]
1124991007977	dimerization interface [polypeptide binding]; other site
1124991007978	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1124991007979	ArsC family; Region: ArsC; pfam03960
1124991007980	putative catalytic residues [active]
1124991007981	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1124991007982	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1124991007983	metal binding site [ion binding]; metal-binding site
1124991007984	dimer interface [polypeptide binding]; other site
1124991007985	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1124991007986	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1124991007987	hypothetical protein; Provisional; Region: PRK10527
1124991007988	benzoylformate decarboxylase; Reviewed; Region: PRK07092
1124991007989	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1124991007990	PYR/PP interface [polypeptide binding]; other site
1124991007991	dimer interface [polypeptide binding]; other site
1124991007992	TPP binding site [chemical binding]; other site
1124991007993	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991007994	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
1124991007995	TPP-binding site [chemical binding]; other site
1124991007996	dimer interface [polypeptide binding]; other site
1124991007997	Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980
1124991007998	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1124991007999	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
1124991008000	Helicase; Region: Helicase_RecD; pfam05127
1124991008001	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991008002	Coenzyme A binding pocket [chemical binding]; other site
1124991008003	Predicted membrane protein [Function unknown]; Region: COG2707
1124991008004	Predicted metalloprotease [General function prediction only]; Region: COG2321
1124991008005	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1124991008006	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1124991008007	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1124991008008	ATP binding site [chemical binding]; other site
1124991008009	active site
1124991008010	substrate binding site [chemical binding]; other site
1124991008011	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1124991008012	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1124991008013	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1124991008014	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1124991008015	Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate,  or similar substrates; Region: Bacterial_IMPase_like_1; cd01641
1124991008016	active site
1124991008017	putative glycosyl transferase; Provisional; Region: PRK10073
1124991008018	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1124991008019	active site
1124991008020	lipoprotein; Provisional; Region: PRK11679
1124991008021	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1124991008022	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1124991008023	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1124991008024	dimer interface [polypeptide binding]; other site
1124991008025	active site
1124991008026	catalytic residue [active]
1124991008027	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1124991008028	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1124991008029	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1124991008030	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1124991008031	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1124991008032	catalytic triad [active]
1124991008033	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1124991008034	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1124991008035	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1124991008036	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1124991008037	Peptidase family M48; Region: Peptidase_M48; cl12018
1124991008038	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1124991008039	TPR motif; other site
1124991008040	binding surface
1124991008041	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1124991008042	ArsC family; Region: ArsC; pfam03960
1124991008043	catalytic residues [active]
1124991008044	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
1124991008045	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
1124991008046	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1124991008047	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
1124991008048	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1124991008049	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1124991008050	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1124991008051	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1124991008052	Putative methyltransferase; Region: Methyltransf_20; pfam12147
1124991008053	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1124991008054	active site
1124991008055	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
1124991008056	active site
1124991008057	catalytic residues [active]
1124991008058	DNA replication initiation factor; Provisional; Region: PRK08084
1124991008059	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1124991008060	uracil transporter; Provisional; Region: PRK10720
1124991008061	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991008062	active site
1124991008063	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1124991008064	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1124991008065	dimerization interface [polypeptide binding]; other site
1124991008066	putative ATP binding site [chemical binding]; other site
1124991008067	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1124991008068	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1124991008069	active site
1124991008070	substrate binding site [chemical binding]; other site
1124991008071	cosubstrate binding site; other site
1124991008072	catalytic site [active]
1124991008073	Pathogenicity locus; Region: Cdd1; pfam11731
1124991008074	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1124991008075	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991008076	Coenzyme A binding pocket [chemical binding]; other site
1124991008077	polyphosphate kinase; Provisional; Region: PRK05443
1124991008078	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1124991008079	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1124991008080	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1124991008081	domain interface [polypeptide binding]; other site
1124991008082	active site
1124991008083	catalytic site [active]
1124991008084	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1124991008085	putative active site [active]
1124991008086	catalytic site [active]
1124991008087	exopolyphosphatase; Provisional; Region: PRK10854
1124991008088	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1124991008089	Mg2+ transporter (mgtE); Region: mgtE; TIGR00400
1124991008090	MgtE intracellular N domain; Region: MgtE_N; smart00924
1124991008091	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1124991008092	Divalent cation transporter; Region: MgtE; pfam01769
1124991008093	metabolite-proton symporter; Region: 2A0106; TIGR00883
1124991008094	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991008095	putative substrate translocation pore; other site
1124991008096	DoxX; Region: DoxX; pfam07681
1124991008097	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1124991008098	active site
1124991008099	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1124991008100	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1124991008101	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991008102	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991008103	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1124991008104	Protein export membrane protein; Region: SecD_SecF; cl14618
1124991008105	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1124991008106	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1124991008107	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991008108	dimerization interface [polypeptide binding]; other site
1124991008109	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991008110	dimer interface [polypeptide binding]; other site
1124991008111	phosphorylation site [posttranslational modification]
1124991008112	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991008113	ATP binding site [chemical binding]; other site
1124991008114	Mg2+ binding site [ion binding]; other site
1124991008115	G-X-G motif; other site
1124991008116	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1124991008117	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991008118	active site
1124991008119	phosphorylation site [posttranslational modification]
1124991008120	intermolecular recognition site; other site
1124991008121	dimerization interface [polypeptide binding]; other site
1124991008122	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991008123	DNA binding site [nucleotide binding]
1124991008124	putative protease; Provisional; Region: PRK15452
1124991008125	Peptidase family U32; Region: Peptidase_U32; pfam01136
1124991008126	lipid kinase; Reviewed; Region: PRK13054
1124991008127	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1124991008128	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1124991008129	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1124991008130	putative active site; other site
1124991008131	catalytic residue [active]
1124991008132	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1124991008133	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991008134	RNA binding surface [nucleotide binding]; other site
1124991008135	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1124991008136	probable active site [active]
1124991008137	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1124991008138	dimer interface [polypeptide binding]; other site
1124991008139	substrate binding site [chemical binding]; other site
1124991008140	ATP binding site [chemical binding]; other site
1124991008141	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991008142	DNA-binding site [nucleotide binding]; DNA binding site
1124991008143	RNA-binding motif; other site
1124991008144	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1124991008145	aromatic amino acid transporter; Provisional; Region: PRK10238
1124991008146	MgrB protein; Region: MgrB; pfam13998
1124991008147	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1124991008148	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991008149	sugar phosphate phosphatase; Provisional; Region: PRK10513
1124991008150	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991008151	active site
1124991008152	motif I; other site
1124991008153	motif II; other site
1124991008154	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991008155	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1124991008156	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1124991008157	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1124991008158	amidase catalytic site [active]
1124991008159	Zn binding residues [ion binding]; other site
1124991008160	substrate binding site [chemical binding]; other site
1124991008161	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1124991008162	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1124991008163	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1124991008164	putative C-terminal domain interface [polypeptide binding]; other site
1124991008165	putative GSH binding site (G-site) [chemical binding]; other site
1124991008166	putative dimer interface [polypeptide binding]; other site
1124991008167	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1124991008168	dimer interface [polypeptide binding]; other site
1124991008169	N-terminal domain interface [polypeptide binding]; other site
1124991008170	substrate binding pocket (H-site) [chemical binding]; other site
1124991008171	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1124991008172	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1124991008173	trimer interface [polypeptide binding]; other site
1124991008174	active site
1124991008175	substrate binding site [chemical binding]; other site
1124991008176	CoA binding site [chemical binding]; other site
1124991008177	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1124991008178	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1124991008179	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1124991008180	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
1124991008181	YfaZ precursor; Region: YfaZ; pfam07437
1124991008182	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1124991008183	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1124991008184	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1124991008185	tetramer interface [polypeptide binding]; other site
1124991008186	heme binding pocket [chemical binding]; other site
1124991008187	NADPH binding site [chemical binding]; other site
1124991008188	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1124991008189	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1124991008190	acyl-activating enzyme (AAE) consensus motif; other site
1124991008191	putative AMP binding site [chemical binding]; other site
1124991008192	putative active site [active]
1124991008193	putative CoA binding site [chemical binding]; other site
1124991008194	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1124991008195	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1124991008196	active site
1124991008197	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1124991008198	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1124991008199	substrate binding site [chemical binding]; other site
1124991008200	oxyanion hole (OAH) forming residues; other site
1124991008201	trimer interface [polypeptide binding]; other site
1124991008202	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1124991008203	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1124991008204	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1124991008205	dimer interface [polypeptide binding]; other site
1124991008206	tetramer interface [polypeptide binding]; other site
1124991008207	PYR/PP interface [polypeptide binding]; other site
1124991008208	TPP binding site [chemical binding]; other site
1124991008209	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1124991008210	TPP-binding site; other site
1124991008211	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1124991008212	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1124991008213	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1124991008214	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991008215	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1124991008216	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991008217	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1124991008218	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1124991008219	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991008220	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1124991008221	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1124991008222	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1124991008223	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991008224	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991008225	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1124991008226	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1124991008227	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991008228	catalytic loop [active]
1124991008229	iron binding site [ion binding]; other site
1124991008230	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; smart00929
1124991008231	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1124991008232	[4Fe-4S] binding site [ion binding]; other site
1124991008233	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1124991008234	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1124991008235	SLBB domain; Region: SLBB; pfam10531
1124991008236	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1124991008237	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1124991008238	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1124991008239	putative dimer interface [polypeptide binding]; other site
1124991008240	[2Fe-2S] cluster binding site [ion binding]; other site
1124991008241	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1124991008242	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1124991008243	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1124991008244	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1124991008245	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1124991008246	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1124991008247	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991008248	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1124991008249	putative dimerization interface [polypeptide binding]; other site
1124991008250	aminotransferase AlaT; Validated; Region: PRK09265
1124991008251	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991008252	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991008253	homodimer interface [polypeptide binding]; other site
1124991008254	catalytic residue [active]
1124991008255	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1124991008256	Zn2+ binding site [ion binding]; other site
1124991008257	Mg2+ binding site [ion binding]; other site
1124991008258	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1124991008259	transmembrane helices; other site
1124991008260	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1124991008261	TrkA-C domain; Region: TrkA_C; pfam02080
1124991008262	TrkA-C domain; Region: TrkA_C; pfam02080
1124991008263	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1124991008264	putative phosphatase; Provisional; Region: PRK11587
1124991008265	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991008266	motif II; other site
1124991008267	hypothetical protein; Validated; Region: PRK05445
1124991008268	hypothetical protein; Provisional; Region: PRK01816
1124991008269	propionate/acetate kinase; Provisional; Region: PRK12379
1124991008270	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1124991008271	phosphate acetyltransferase; Reviewed; Region: PRK05632
1124991008272	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1124991008273	DRTGG domain; Region: DRTGG; pfam07085
1124991008274	phosphate acetyltransferase; Region: pta; TIGR00651
1124991008275	Peptidase family M48; Region: Peptidase_M48; cl12018
1124991008276	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1124991008277	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1124991008278	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1124991008279	nudix motif; other site
1124991008280	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1124991008281	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1124991008282	putative NAD(P) binding site [chemical binding]; other site
1124991008283	putative active site [active]
1124991008284	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1124991008285	Flavoprotein; Region: Flavoprotein; pfam02441
1124991008286	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1124991008287	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1124991008288	active site
1124991008289	tetramer interface [polypeptide binding]; other site
1124991008290	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991008291	active site
1124991008292	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1124991008293	Colicin V production protein; Region: Colicin_V; cl00567
1124991008294	Sporulation related domain; Region: SPOR; pfam05036
1124991008295	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1124991008296	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991008297	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991008298	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1124991008299	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1124991008300	hypothetical protein; Provisional; Region: PRK10847
1124991008301	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1124991008302	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1124991008303	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1124991008304	dimerization interface 3.5A [polypeptide binding]; other site
1124991008305	active site
1124991008306	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1124991008307	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1124991008308	Pleckstrin homology-like domain; Region: PH-like; cl17171
1124991008309	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1124991008310	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1124991008311	ligand binding site [chemical binding]; other site
1124991008312	NAD binding site [chemical binding]; other site
1124991008313	catalytic site [active]
1124991008314	homodimer interface [polypeptide binding]; other site
1124991008315	Cupin domain; Region: Cupin_2; pfam07883
1124991008316	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1124991008317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991008318	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991008319	EamA-like transporter family; Region: EamA; pfam00892
1124991008320	EamA-like transporter family; Region: EamA; pfam00892
1124991008321	Colicin pore forming domain; Region: Colicin; pfam01024
1124991008322	YjbD family (DUF3811); Region: DUF3811; cl08125
1124991008323	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1124991008324	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1124991008325	dimer interface [polypeptide binding]; other site
1124991008326	active site
1124991008327	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1124991008328	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1124991008329	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991008330	Glutaminase; Region: Glutaminase; cl00907
1124991008331	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1124991008332	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1124991008333	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991008334	Coenzyme A binding pocket [chemical binding]; other site
1124991008335	YfcL protein; Region: YfcL; pfam08891
1124991008336	Protein of unknown function, DUF462; Region: DUF462; cl01190
1124991008337	hypothetical protein; Provisional; Region: PRK10621
1124991008338	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991008339	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1124991008340	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1124991008341	Tetramer interface [polypeptide binding]; other site
1124991008342	active site
1124991008343	FMN-binding site [chemical binding]; other site
1124991008344	HemK family putative methylases; Region: hemK_fam; TIGR00536
1124991008345	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991008346	S-adenosylmethionine binding site [chemical binding]; other site
1124991008347	hypothetical protein; Provisional; Region: PRK04946
1124991008348	Smr domain; Region: Smr; pfam01713
1124991008349	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1124991008350	catalytic core [active]
1124991008351	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1124991008352	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1124991008353	substrate binding site [chemical binding]; other site
1124991008354	oxyanion hole (OAH) forming residues; other site
1124991008355	trimer interface [polypeptide binding]; other site
1124991008356	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1124991008357	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1124991008358	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1124991008359	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1124991008360	dimer interface [polypeptide binding]; other site
1124991008361	active site
1124991008362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1124991008363	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1124991008364	VacJ like lipoprotein; Region: VacJ; cl01073
1124991008365	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1124991008366	pyrroline-5-carboxylate reductase; Region: PLN02688
1124991008367	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1124991008368	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1124991008369	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991008370	catalytic residue [active]
1124991008371	permease DsdX; Provisional; Region: PRK09921
1124991008372	gluconate transporter; Region: gntP; TIGR00791
1124991008373	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1124991008374	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991008375	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1124991008376	dimerization interface [polypeptide binding]; other site
1124991008377	substrate binding pocket [chemical binding]; other site
1124991008378	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1124991008379	catalytic residues [active]
1124991008380	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008381	non-specific DNA binding site [nucleotide binding]; other site
1124991008382	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1124991008383	salt bridge; other site
1124991008384	sequence-specific DNA binding site [nucleotide binding]; other site
1124991008385	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991008386	Catalytic site [active]
1124991008387	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1124991008388	lipoprotein, YaeC family; Region: TIGR00363
1124991008389	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1124991008390	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991008391	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1124991008392	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1124991008393	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1124991008394	active site
1124991008395	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991008396	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1124991008397	Predicted acetyltransferase [General function prediction only]; Region: COG3393
1124991008398	Protein of unknown function (DUF465); Region: DUF465; cl01070
1124991008399	Protein of unknown function (DUF3088); Region: DUF3088; pfam11287
1124991008400	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
1124991008401	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1124991008402	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1124991008403	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1124991008404	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1124991008405	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1124991008406	putative ligand binding residues [chemical binding]; other site
1124991008407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1124991008408	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991008409	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008410	non-specific DNA binding site [nucleotide binding]; other site
1124991008411	salt bridge; other site
1124991008412	sequence-specific DNA binding site [nucleotide binding]; other site
1124991008413	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1124991008414	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1124991008415	NADP binding site [chemical binding]; other site
1124991008416	Predicted transcriptional regulators [Transcription]; Region: COG1733
1124991008417	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1124991008418	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991008419	active site
1124991008420	DNA binding site [nucleotide binding]
1124991008421	Int/Topo IB signature motif; other site
1124991008422	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1124991008423	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1124991008424	DNA binding site [nucleotide binding]
1124991008425	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1124991008426	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991008427	Catalytic site [active]
1124991008428	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1124991008429	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1124991008430	putative active site [active]
1124991008431	putative NTP binding site [chemical binding]; other site
1124991008432	putative nucleic acid binding site [nucleotide binding]; other site
1124991008433	Protein of unknown function (DUF1360); Region: DUF1360; pfam07098
1124991008434	Phage-related protein, tail component [Function unknown]; Region: COG4733
1124991008435	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1124991008436	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1124991008437	Interdomain contacts; other site
1124991008438	Cytokine receptor motif; other site
1124991008439	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1124991008440	Phage-related protein, tail component [Function unknown]; Region: COG4723
1124991008441	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1124991008442	MPN+ (JAMM) motif; other site
1124991008443	Zinc-binding site [ion binding]; other site
1124991008444	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1124991008445	NlpC/P60 family; Region: NLPC_P60; pfam00877
1124991008446	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1124991008447	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1124991008448	Phage-related minor tail protein [Function unknown]; Region: COG5281
1124991008449	tape measure domain; Region: tape_meas_nterm; TIGR02675
1124991008450	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
1124991008451	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1124991008452	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1124991008453	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
1124991008454	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
1124991008455	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
1124991008456	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
1124991008457	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
1124991008458	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1124991008459	oligomerization interface [polypeptide binding]; other site
1124991008460	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1124991008461	Phage capsid family; Region: Phage_capsid; pfam05065
1124991008462	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
1124991008463	Phage-related protein [Function unknown]; Region: COG4695
1124991008464	Phage portal protein; Region: Phage_portal; pfam04860
1124991008465	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1124991008466	Phage terminase, small subunit; Region: Terminase_4; cl01525
1124991008467	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1124991008468	catalytic residues [active]
1124991008469	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1124991008470	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1124991008471	putative acyl-acceptor binding pocket; other site
1124991008472	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991008473	DNA-binding site [nucleotide binding]; DNA binding site
1124991008474	RNA-binding motif; other site
1124991008475	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1124991008476	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1124991008477	KilA-N domain; Region: KilA-N; pfam04383
1124991008478	Helix-turn-helix domain; Region: HTH_36; pfam13730
1124991008479	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1124991008480	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1124991008481	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008482	non-specific DNA binding site [nucleotide binding]; other site
1124991008483	salt bridge; other site
1124991008484	sequence-specific DNA binding site [nucleotide binding]; other site
1124991008485	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991008486	Catalytic site [active]
1124991008487	Excisionase-like protein; Region: Exc; pfam07825
1124991008488	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1124991008489	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991008490	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991008491	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991008492	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991008493	isocitrate dehydrogenase; Validated; Region: PRK07362
1124991008494	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1124991008495	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1124991008496	pseudouridine synthase; Region: TIGR00093
1124991008497	active site
1124991008498	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1124991008499	nudix motif; other site
1124991008500	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1124991008501	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1124991008502	putative lysogenization regulator; Reviewed; Region: PRK00218
1124991008503	adenylosuccinate lyase; Provisional; Region: PRK09285
1124991008504	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1124991008505	tetramer interface [polypeptide binding]; other site
1124991008506	active site
1124991008507	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1124991008508	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991008509	active site
1124991008510	phosphorylation site [posttranslational modification]
1124991008511	intermolecular recognition site; other site
1124991008512	dimerization interface [polypeptide binding]; other site
1124991008513	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991008514	DNA binding site [nucleotide binding]
1124991008515	sensor protein PhoQ; Provisional; Region: PRK10815
1124991008516	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1124991008517	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1124991008518	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1124991008519	dimer interface [polypeptide binding]; other site
1124991008520	phosphorylation site [posttranslational modification]
1124991008521	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991008522	ATP binding site [chemical binding]; other site
1124991008523	Mg2+ binding site [ion binding]; other site
1124991008524	G-X-G motif; other site
1124991008525	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1124991008526	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991008527	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1124991008528	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991008529	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991008530	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991008531	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1124991008532	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991008533	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991008534	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991008535	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1124991008536	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1124991008537	metal binding site [ion binding]; metal-binding site
1124991008538	dimer interface [polypeptide binding]; other site
1124991008539	NAD-dependent deacetylase; Provisional; Region: PRK00481
1124991008540	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1124991008541	NAD+ binding site [chemical binding]; other site
1124991008542	substrate binding site [chemical binding]; other site
1124991008543	Zn binding site [ion binding]; other site
1124991008544	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1124991008545	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1124991008546	FtsX-like permease family; Region: FtsX; pfam02687
1124991008547	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1124991008548	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1124991008549	Walker A/P-loop; other site
1124991008550	ATP binding site [chemical binding]; other site
1124991008551	Q-loop/lid; other site
1124991008552	ABC transporter signature motif; other site
1124991008553	Walker B; other site
1124991008554	D-loop; other site
1124991008555	H-loop/switch region; other site
1124991008556	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1124991008557	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1124991008558	FtsX-like permease family; Region: FtsX; pfam02687
1124991008559	transcription-repair coupling factor; Provisional; Region: PRK10689
1124991008560	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1124991008561	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991008562	ATP binding site [chemical binding]; other site
1124991008563	putative Mg++ binding site [ion binding]; other site
1124991008564	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991008565	nucleotide binding region [chemical binding]; other site
1124991008566	ATP-binding site [chemical binding]; other site
1124991008567	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1124991008568	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1124991008569	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991008570	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991008571	homodimer interface [polypeptide binding]; other site
1124991008572	catalytic residue [active]
1124991008573	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1124991008574	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1124991008575	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991008576	hypothetical protein; Provisional; Region: PRK04940
1124991008577	beta-hexosaminidase; Provisional; Region: PRK05337
1124991008578	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1124991008579	thiamine kinase; Region: ycfN_thiK; TIGR02721
1124991008580	active site
1124991008581	substrate binding site [chemical binding]; other site
1124991008582	ATP binding site [chemical binding]; other site
1124991008583	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1124991008584	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1124991008585	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1124991008586	nucleotide binding site/active site [active]
1124991008587	HIT family signature motif; other site
1124991008588	catalytic residue [active]
1124991008589	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1124991008590	active site
1124991008591	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1124991008592	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1124991008593	thymidylate kinase; Validated; Region: tmk; PRK00698
1124991008594	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1124991008595	TMP-binding site; other site
1124991008596	ATP-binding site [chemical binding]; other site
1124991008597	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1124991008598	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1124991008599	dimerization interface [polypeptide binding]; other site
1124991008600	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1124991008601	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1124991008602	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991008603	catalytic residue [active]
1124991008604	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1124991008605	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1124991008606	dimer interface [polypeptide binding]; other site
1124991008607	active site
1124991008608	acyl carrier protein; Provisional; Region: acpP; PRK00982
1124991008609	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1124991008610	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1124991008611	NAD(P) binding site [chemical binding]; other site
1124991008612	homotetramer interface [polypeptide binding]; other site
1124991008613	homodimer interface [polypeptide binding]; other site
1124991008614	active site
1124991008615	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1124991008616	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1124991008617	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1124991008618	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1124991008619	dimer interface [polypeptide binding]; other site
1124991008620	active site
1124991008621	CoA binding pocket [chemical binding]; other site
1124991008622	putative phosphate acyltransferase; Provisional; Region: PRK05331
1124991008623	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1124991008624	hypothetical protein; Provisional; Region: PRK11193
1124991008625	Maf-like protein; Region: Maf; pfam02545
1124991008626	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1124991008627	active site
1124991008628	dimer interface [polypeptide binding]; other site
1124991008629	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1124991008630	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991008631	RNA binding surface [nucleotide binding]; other site
1124991008632	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1124991008633	active site
1124991008634	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1124991008635	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1124991008636	homodimer interface [polypeptide binding]; other site
1124991008637	oligonucleotide binding site [chemical binding]; other site
1124991008638	hypothetical protein; Provisional; Region: PRK05423
1124991008639	exonuclease I; Provisional; Region: sbcB; PRK11779
1124991008640	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1124991008641	active site
1124991008642	catalytic site [active]
1124991008643	substrate binding site [chemical binding]; other site
1124991008644	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1124991008645	D-lactate dehydrogenase; Provisional; Region: PRK11183
1124991008646	FAD binding domain; Region: FAD_binding_4; pfam01565
1124991008647	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1124991008648	hypothetical protein; Provisional; Region: PRK10621
1124991008649	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991008650	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1124991008651	putative outer membrane receptor; Provisional; Region: PRK13513
1124991008652	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991008653	N-terminal plug; other site
1124991008654	ligand-binding site [chemical binding]; other site
1124991008655	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1124991008656	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1124991008657	Walker A/P-loop; other site
1124991008658	ATP binding site [chemical binding]; other site
1124991008659	Q-loop/lid; other site
1124991008660	ABC transporter signature motif; other site
1124991008661	Walker B; other site
1124991008662	D-loop; other site
1124991008663	H-loop/switch region; other site
1124991008664	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1124991008665	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1124991008666	ABC-ATPase subunit  interface; other site
1124991008667	dimer interface [polypeptide binding]; other site
1124991008668	putative PBP binding regions; other site
1124991008669	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1124991008670	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1124991008671	putative ligand binding residues [chemical binding]; other site
1124991008672	lysine transporter; Provisional; Region: PRK10836
1124991008673	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1124991008674	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991008675	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1124991008676	putative dimerization interface [polypeptide binding]; other site
1124991008677	Predicted membrane protein [Function unknown]; Region: COG2855
1124991008678	endonuclease IV; Provisional; Region: PRK01060
1124991008679	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1124991008680	AP (apurinic/apyrimidinic) site pocket; other site
1124991008681	DNA interaction; other site
1124991008682	Metal-binding active site; metal-binding site
1124991008683	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1124991008684	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1124991008685	putative substrate binding site [chemical binding]; other site
1124991008686	putative ATP binding site [chemical binding]; other site
1124991008687	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1124991008688	nudix motif; other site
1124991008689	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1124991008690	aromatic amino acid transport protein; Region: araaP; TIGR00837
1124991008691	elongation factor P; Provisional; Region: PRK04542
1124991008692	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1124991008693	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1124991008694	RNA binding site [nucleotide binding]; other site
1124991008695	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1124991008696	RNA binding site [nucleotide binding]; other site
1124991008697	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991008698	Fimbrial protein; Region: Fimbrial; cl01416
1124991008699	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1124991008700	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1124991008701	active site
1124991008702	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1124991008703	NlpC/P60 family; Region: NLPC_P60; pfam00877
1124991008704	YejG-like protein; Region: YejG; cl08201
1124991008705	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991008706	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1124991008707	putative substrate translocation pore; other site
1124991008708	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1124991008709	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991008710	RNA binding surface [nucleotide binding]; other site
1124991008711	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1124991008712	active site
1124991008713	uracil binding [chemical binding]; other site
1124991008714	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1124991008715	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1124991008716	ATP binding site [chemical binding]; other site
1124991008717	putative Mg++ binding site [ion binding]; other site
1124991008718	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1124991008719	nucleotide binding region [chemical binding]; other site
1124991008720	ATP-binding site [chemical binding]; other site
1124991008721	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1124991008722	5S rRNA interface [nucleotide binding]; other site
1124991008723	CTC domain interface [polypeptide binding]; other site
1124991008724	L16 interface [polypeptide binding]; other site
1124991008725	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1124991008726	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1124991008727	hypothetical protein; Provisional; Region: PRK13689
1124991008728	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1124991008729	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1124991008730	Sulfatase; Region: Sulfatase; cl17466
1124991008731	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991008732	DNA-binding site [nucleotide binding]; DNA binding site
1124991008733	RNA-binding motif; other site
1124991008734	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1124991008735	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1124991008736	Active Sites [active]
1124991008737	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1124991008738	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1124991008739	ParB-like nuclease domain; Region: ParBc; pfam02195
1124991008740	hypothetical protein; Provisional; Region: PRK10621
1124991008741	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1124991008742	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
1124991008743	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1124991008744	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1124991008745	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1124991008746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991008747	S-adenosylmethionine binding site [chemical binding]; other site
1124991008748	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1124991008749	DNA-binding site [nucleotide binding]; DNA binding site
1124991008750	RNA-binding motif; other site
1124991008751	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1124991008752	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1124991008753	putative metal binding site [ion binding]; other site
1124991008754	putative homodimer interface [polypeptide binding]; other site
1124991008755	putative homotetramer interface [polypeptide binding]; other site
1124991008756	putative homodimer-homodimer interface [polypeptide binding]; other site
1124991008757	putative allosteric switch controlling residues; other site
1124991008758	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1124991008759	homotrimer interaction site [polypeptide binding]; other site
1124991008760	putative active site [active]
1124991008761	putative transporter; Provisional; Region: PRK10054
1124991008762	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991008763	putative substrate translocation pore; other site
1124991008764	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991008765	putative Zn2+ binding site [ion binding]; other site
1124991008766	putative DNA binding site [nucleotide binding]; other site
1124991008767	O-methyltransferase; Region: Methyltransf_2; pfam00891
1124991008768	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1124991008769	B12 binding site [chemical binding]; other site
1124991008770	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1124991008771	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
1124991008772	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1124991008773	putative di-iron ligands [ion binding]; other site
1124991008774	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1124991008775	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1124991008776	active site
1124991008777	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1124991008778	B12 binding site [chemical binding]; other site
1124991008779	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1124991008780	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991008781	FeS/SAM binding site; other site
1124991008782	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1124991008783	B12 binding site [chemical binding]; other site
1124991008784	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1124991008785	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1124991008786	FeS/SAM binding site; other site
1124991008787	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1124991008788	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1124991008789	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1124991008790	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991008791	FeS/SAM binding site; other site
1124991008792	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1124991008793	B12 binding site [chemical binding]; other site
1124991008794	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1124991008795	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991008796	FeS/SAM binding site; other site
1124991008797	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1124991008798	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cl09835
1124991008799	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cl09832
1124991008800	CRISPR-associated protein (Cas_Csy2); Region: Cas_Csy2; pfam09614
1124991008801	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cl09829
1124991008802	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3544
1124991008803	integrase; Provisional; Region: int; PHA02601
1124991008804	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1124991008805	dimer interface [polypeptide binding]; other site
1124991008806	active site
1124991008807	catalytic residues [active]
1124991008808	Int/Topo IB signature motif; other site
1124991008809	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1124991008810	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008811	non-specific DNA binding site [nucleotide binding]; other site
1124991008812	salt bridge; other site
1124991008813	sequence-specific DNA binding site [nucleotide binding]; other site
1124991008814	DksA-like zinc finger domain containing protein; Region: PHA00080
1124991008815	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1124991008816	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1124991008817	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991008818	Walker A/P-loop; other site
1124991008819	ATP binding site [chemical binding]; other site
1124991008820	AAA domain; Region: AAA_21; pfam13304
1124991008821	portal vertex protein; Provisional; Region: Q; PHA02536
1124991008822	Phage portal protein; Region: Phage_portal; pfam04860
1124991008823	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1124991008824	terminase ATPase subunit; Provisional; Region: P; PHA02535
1124991008825	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1124991008826	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
1124991008827	capsid protein; Provisional; Region: N; PHA02538
1124991008828	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1124991008829	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1124991008830	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1124991008831	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1124991008832	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
1124991008833	virion protein; Provisional; Region: V; PHA02564
1124991008834	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1124991008835	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1124991008836	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1124991008837	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1124991008838	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1124991008839	baseplate assembly protein; Provisional; Region: J; PHA02568
1124991008840	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1124991008841	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1124991008842	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1124991008843	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1124991008844	major tail sheath protein; Provisional; Region: FI; PHA02560
1124991008845	Phage tail tube protein FII; Region: Phage_tube; pfam04985
1124991008846	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1124991008847	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1124991008848	membrane protein P6; Region: PHA01399
1124991008849	Phage protein U [General function prediction only]; Region: COG3499
1124991008850	tail protein; Provisional; Region: D; PHA02561
1124991008851	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1124991008852	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1124991008853	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1124991008854	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1124991008855	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1124991008856	GIY-YIG motif/motif A; other site
1124991008857	active site
1124991008858	catalytic site [active]
1124991008859	putative DNA binding site [nucleotide binding]; other site
1124991008860	metal binding site [ion binding]; metal-binding site
1124991008861	UvrB/uvrC motif; Region: UVR; pfam02151
1124991008862	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1124991008863	response regulator; Provisional; Region: PRK09483
1124991008864	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991008865	active site
1124991008866	phosphorylation site [posttranslational modification]
1124991008867	intermolecular recognition site; other site
1124991008868	dimerization interface [polypeptide binding]; other site
1124991008869	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1124991008870	DNA binding residues [nucleotide binding]
1124991008871	dimerization interface [polypeptide binding]; other site
1124991008872	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1124991008873	dimer interface [polypeptide binding]; other site
1124991008874	FMN binding site [chemical binding]; other site
1124991008875	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1124991008876	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1124991008877	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1124991008878	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1124991008879	tetramer interface [polypeptide binding]; other site
1124991008880	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991008881	catalytic residue [active]
1124991008882	3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826
1124991008883	classical (c) SDRs; Region: SDR_c; cd05233
1124991008884	NAD(P) binding site [chemical binding]; other site
1124991008885	active site
1124991008886	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1124991008887	Imelysin; Region: Peptidase_M75; pfam09375
1124991008888	Iron permease FTR1 family; Region: FTR1; cl00475
1124991008889	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1124991008890	Fe2+ transport protein; Region: Iron_transport; pfam10634
1124991008891	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1124991008892	conserved cys residue [active]
1124991008893	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1124991008894	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1124991008895	nucleotide binding site/active site [active]
1124991008896	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1124991008897	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1124991008898	HIGH motif; other site
1124991008899	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1124991008900	active site
1124991008901	KMSKS motif; other site
1124991008902	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1124991008903	classical (c) SDRs; Region: SDR_c; cd05233
1124991008904	NAD(P) binding site [chemical binding]; other site
1124991008905	active site
1124991008906	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1124991008907	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991008908	putative DNA binding site [nucleotide binding]; other site
1124991008909	putative Zn2+ binding site [ion binding]; other site
1124991008910	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1124991008911	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1124991008912	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1124991008913	nucleotide binding pocket [chemical binding]; other site
1124991008914	K-X-D-G motif; other site
1124991008915	catalytic site [active]
1124991008916	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1124991008917	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1124991008918	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1124991008919	Dimer interface [polypeptide binding]; other site
1124991008920	BRCT sequence motif; other site
1124991008921	cell division protein ZipA; Provisional; Region: PRK03427
1124991008922	ZipA, C-terminal FtsZ-binding domain; Region: ZipA_C; pfam04354
1124991008923	FtsZ protein binding site [polypeptide binding]; other site
1124991008924	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1124991008925	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1124991008926	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1124991008927	dimer interface [polypeptide binding]; other site
1124991008928	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991008929	catalytic residue [active]
1124991008930	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1124991008931	dimerization domain swap beta strand [polypeptide binding]; other site
1124991008932	regulatory protein interface [polypeptide binding]; other site
1124991008933	active site
1124991008934	regulatory phosphorylation site [posttranslational modification]; other site
1124991008935	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1124991008936	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1124991008937	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1124991008938	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1124991008939	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1124991008940	HPr interaction site; other site
1124991008941	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1124991008942	active site
1124991008943	phosphorylation site [posttranslational modification]
1124991008944	Protein of unknown function (DUF3024); Region: DUF3024; pfam11225
1124991008945	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991008946	Ligand Binding Site [chemical binding]; other site
1124991008947	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1124991008948	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991008949	Coenzyme A binding pocket [chemical binding]; other site
1124991008950	benzoate transporter; Region: benE; TIGR00843
1124991008951	Benzoate membrane transport protein; Region: BenE; pfam03594
1124991008952	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1124991008953	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008954	non-specific DNA binding site [nucleotide binding]; other site
1124991008955	salt bridge; other site
1124991008956	sequence-specific DNA binding site [nucleotide binding]; other site
1124991008957	Cupin domain; Region: Cupin_2; pfam07883
1124991008958	Chloramphenicol acetyltransferase; Region: CAT; pfam00302
1124991008959	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1124991008960	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1124991008961	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991008962	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991008963	SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases; Region: XynE_like; cd01830
1124991008964	active site
1124991008965	catalytic triad [active]
1124991008966	oxyanion hole [active]
1124991008967	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
1124991008968	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1124991008969	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1124991008970	Head binding; Region: Head_binding; pfam09008
1124991008971	Mnt; Region: mnt; PHA01513
1124991008972	Arc-like DNA binding domain; Region: Arc; pfam03869
1124991008973	Regulatory protein Mnt; Region: Repressor_Mnt; pfam11423
1124991008974	YjzC-like protein; Region: YjzC; pfam14168
1124991008975	hypothetical protein; Region: PHA00527
1124991008976	Protein of unknown function (DUF2824); Region: DUF2824; cl10279
1124991008977	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
1124991008978	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
1124991008979	coat protein; Region: PHA01511
1124991008980	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1124991008981	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
1124991008982	Terminase-like family; Region: Terminase_6; pfam03237
1124991008983	Protein of unknown function (DUF2560); Region: DUF2560; cl10280
1124991008984	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1124991008985	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1124991008986	Phage NinH protein; Region: Phage_NinH; pfam06322
1124991008987	hypothetical protein; Provisional; Region: PRK09741
1124991008988	replicative DNA helicase; Region: DnaB; TIGR00665
1124991008989	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1124991008990	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1124991008991	Walker A motif; other site
1124991008992	ATP binding site [chemical binding]; other site
1124991008993	Walker B motif; other site
1124991008994	DNA binding loops [nucleotide binding]
1124991008995	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1124991008996	Cro; Region: Cro; pfam09048
1124991008997	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991008998	non-specific DNA binding site [nucleotide binding]; other site
1124991008999	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1124991009000	salt bridge; other site
1124991009001	sequence-specific DNA binding site [nucleotide binding]; other site
1124991009002	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1124991009003	Catalytic site [active]
1124991009004	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1124991009005	active site
1124991009006	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1124991009007	RecT family; Region: RecT; cl04285
1124991009008	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1124991009009	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1124991009010	Protein of unknown function (DUF2528); Region: DUF2528; pfam10800
1124991009011	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1124991009012	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1124991009013	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1124991009014	integrase; Provisional; Region: int; PHA02601
1124991009015	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1124991009016	Int/Topo IB signature motif; other site
1124991009017	tyrosine phenol-lyase; Provisional; Region: PRK13237
1124991009018	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1124991009019	substrate binding site [chemical binding]; other site
1124991009020	tetramer interface [polypeptide binding]; other site
1124991009021	catalytic residue [active]
1124991009022	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1124991009023	aromatic amino acid transport protein; Region: araaP; TIGR00837
1124991009024	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1124991009025	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1124991009026	Nucleoside recognition; Region: Gate; pfam07670
1124991009027	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1124991009028	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1124991009029	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1124991009030	putative MFS family transporter protein; Provisional; Region: PRK03633
1124991009031	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991009032	putative substrate translocation pore; other site
1124991009033	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1124991009034	putative iron-regulated outer membrane virulence protein; Provisional; Region: PRK13484
1124991009035	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991009036	N-terminal plug; other site
1124991009037	ligand-binding site [chemical binding]; other site
1124991009038	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1124991009039	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991009040	DNA binding site [nucleotide binding]
1124991009041	domain linker motif; other site
1124991009042	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1124991009043	dimerization interface (closed form) [polypeptide binding]; other site
1124991009044	ligand binding site [chemical binding]; other site
1124991009045	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1124991009046	dimer interface [polypeptide binding]; other site
1124991009047	putative tRNA-binding site [nucleotide binding]; other site
1124991009048	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1124991009049	active site
1124991009050	catalytic residues [active]
1124991009051	galactokinase; Provisional; Region: PRK05101
1124991009052	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1124991009053	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1124991009054	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1124991009055	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1124991009056	dimer interface [polypeptide binding]; other site
1124991009057	active site
1124991009058	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1124991009059	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1124991009060	NAD binding site [chemical binding]; other site
1124991009061	homodimer interface [polypeptide binding]; other site
1124991009062	active site
1124991009063	substrate binding site [chemical binding]; other site
1124991009064	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1124991009065	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991009066	DNA binding site [nucleotide binding]
1124991009067	domain linker motif; other site
1124991009068	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1124991009069	putative dimerization interface [polypeptide binding]; other site
1124991009070	putative ligand binding site [chemical binding]; other site
1124991009071	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1124991009072	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1124991009073	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1124991009074	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1124991009075	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1124991009076	Domain of unknown function (DUF386); Region: DUF386; cl01047
1124991009077	inner membrane transporter YjeM; Provisional; Region: PRK15238
1124991009078	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1124991009079	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1124991009080	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1124991009081	dimerization interface [polypeptide binding]; other site
1124991009082	ligand binding site [chemical binding]; other site
1124991009083	NADP binding site [chemical binding]; other site
1124991009084	catalytic site [active]
1124991009085	Mig-14; Region: Mig-14; pfam07395
1124991009086	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1124991009087	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1124991009088	Cation efflux family; Region: Cation_efflux; pfam01545
1124991009089	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1124991009090	Ligand Binding Site [chemical binding]; other site
1124991009091	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1124991009092	Transposase domain (DUF772); Region: DUF772; pfam05598
1124991009093	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1124991009094	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1124991009095	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cl00178
1124991009096	secondary substrate binding site; other site
1124991009097	primary substrate binding site; other site
1124991009098	inhibition loop; other site
1124991009099	dimerization interface [polypeptide binding]; other site
1124991009100	Protein of unknown function (DUF465); Region: DUF465; cl01070
1124991009101	probable metal-binding protein; Region: matur_matur; TIGR03853
1124991009102	DinI-like family; Region: DinI; cl11630
1124991009103	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1124991009104	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1124991009105	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1124991009106	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1124991009107	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1124991009108	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991009109	Walker A/P-loop; other site
1124991009110	ATP binding site [chemical binding]; other site
1124991009111	Q-loop/lid; other site
1124991009112	ABC transporter signature motif; other site
1124991009113	Walker B; other site
1124991009114	D-loop; other site
1124991009115	H-loop/switch region; other site
1124991009116	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1124991009117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991009118	dimer interface [polypeptide binding]; other site
1124991009119	conserved gate region; other site
1124991009120	putative PBP binding loops; other site
1124991009121	ABC-ATPase subunit interface; other site
1124991009122	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1124991009123	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1124991009124	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991009125	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1124991009126	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1124991009127	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1124991009128	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1124991009129	GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043
1124991009130	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1124991009131	putative C-terminal domain interface [polypeptide binding]; other site
1124991009132	putative GSH binding site (G-site) [chemical binding]; other site
1124991009133	putative dimer interface [polypeptide binding]; other site
1124991009134	C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194
1124991009135	putative substrate binding pocket (H-site) [chemical binding]; other site
1124991009136	putative N-terminal domain interface [polypeptide binding]; other site
1124991009137	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991009138	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991009139	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1124991009140	putative effector binding pocket; other site
1124991009141	dimerization interface [polypeptide binding]; other site
1124991009142	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1124991009143	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1124991009144	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1124991009145	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991009146	dimerization interface [polypeptide binding]; other site
1124991009147	putative DNA binding site [nucleotide binding]; other site
1124991009148	putative Zn2+ binding site [ion binding]; other site
1124991009149	Protein of unknown function (DUF2798); Region: DUF2798; pfam11391
1124991009150	DKNYY family; Region: DKNYY; pfam13644
1124991009151	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991009152	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991009153	putrescine transporter; Provisional; Region: potE; PRK10655
1124991009154	ornithine decarboxylase; Provisional; Region: PRK13578
1124991009155	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1124991009156	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1124991009157	homodimer interface [polypeptide binding]; other site
1124991009158	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991009159	catalytic residue [active]
1124991009160	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1124991009161	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1124991009162	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1124991009163	dimer interface [polypeptide binding]; other site
1124991009164	putative anticodon binding site; other site
1124991009165	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1124991009166	motif 1; other site
1124991009167	active site
1124991009168	motif 2; other site
1124991009169	motif 3; other site
1124991009170	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1124991009171	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1124991009172	RF-1 domain; Region: RF-1; pfam00472
1124991009173	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1124991009174	DHH family; Region: DHH; pfam01368
1124991009175	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1124991009176	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1124991009177	dimerization domain [polypeptide binding]; other site
1124991009178	dimer interface [polypeptide binding]; other site
1124991009179	catalytic residues [active]
1124991009180	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1124991009181	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1124991009182	active site
1124991009183	Int/Topo IB signature motif; other site
1124991009184	flavodoxin FldB; Provisional; Region: PRK12359
1124991009185	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1124991009186	Uncharacterized conserved protein [Function unknown]; Region: COG2938
1124991009187	putative global regulator; Reviewed; Region: PRK09559
1124991009188	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1124991009189	HD domain; Region: HD_3; pfam13023
1124991009190	glycine dehydrogenase; Provisional; Region: PRK05367
1124991009191	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1124991009192	tetramer interface [polypeptide binding]; other site
1124991009193	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991009194	catalytic residue [active]
1124991009195	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1124991009196	tetramer interface [polypeptide binding]; other site
1124991009197	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991009198	catalytic residue [active]
1124991009199	glycine cleavage system protein H; Provisional; Region: PRK13380
1124991009200	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1124991009201	lipoyl attachment site [posttranslational modification]; other site
1124991009202	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1124991009203	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1124991009204	oxidoreductase; Provisional; Region: PRK08013
1124991009205	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1124991009206	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1124991009207	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1124991009208	proline aminopeptidase P II; Provisional; Region: PRK10879
1124991009209	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1124991009210	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1124991009211	active site
1124991009212	hypothetical protein; Reviewed; Region: PRK01736
1124991009213	Cell division protein ZapA; Region: ZapA; cl01146
1124991009214	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1124991009215	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1124991009216	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1124991009217	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1124991009218	ligand binding site [chemical binding]; other site
1124991009219	NAD binding site [chemical binding]; other site
1124991009220	tetramer interface [polypeptide binding]; other site
1124991009221	catalytic site [active]
1124991009222	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1124991009223	L-serine binding site [chemical binding]; other site
1124991009224	ACT domain interface; other site
1124991009225	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1124991009226	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1124991009227	active site
1124991009228	dimer interface [polypeptide binding]; other site
1124991009229	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1124991009230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991009231	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1124991009232	putative dimerization interface [polypeptide binding]; other site
1124991009233	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1124991009234	oxidative stress defense protein; Provisional; Region: PRK11087
1124991009235	arginine exporter protein; Provisional; Region: PRK09304
1124991009236	mechanosensitive channel MscS; Provisional; Region: PRK10334
1124991009237	Conserved TM helix; Region: TM_helix; pfam05552
1124991009238	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991009239	hypothetical protein; Provisional; Region: PRK05248
1124991009240	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1124991009241	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1124991009242	substrate binding site [chemical binding]; other site
1124991009243	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1124991009244	substrate binding site [chemical binding]; other site
1124991009245	ligand binding site [chemical binding]; other site
1124991009246	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1124991009247	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1124991009248	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991009249	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1124991009250	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1124991009251	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1124991009252	E3 interaction surface; other site
1124991009253	lipoyl attachment site [posttranslational modification]; other site
1124991009254	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1124991009255	E3 interaction surface; other site
1124991009256	lipoyl attachment site [posttranslational modification]; other site
1124991009257	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1124991009258	E3 interaction surface; other site
1124991009259	lipoyl attachment site [posttranslational modification]; other site
1124991009260	e3 binding domain; Region: E3_binding; pfam02817
1124991009261	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1124991009262	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1124991009263	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1124991009264	dimer interface [polypeptide binding]; other site
1124991009265	TPP-binding site [chemical binding]; other site
1124991009266	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
1124991009267	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1124991009268	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991009269	DNA-binding site [nucleotide binding]; DNA binding site
1124991009270	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1124991009271	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1124991009272	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1124991009273	amidase catalytic site [active]
1124991009274	substrate binding site [chemical binding]; other site
1124991009275	Zn binding residues [ion binding]; other site
1124991009276	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1124991009277	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cl02712
1124991009278	putative major pilin subunit; Provisional; Region: PRK10574
1124991009279	hypothetical protein; Provisional; Region: PRK10436
1124991009280	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1124991009281	Walker A motif; other site
1124991009282	ATP binding site [chemical binding]; other site
1124991009283	Walker B motif; other site
1124991009284	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1124991009285	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1124991009286	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1124991009287	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1124991009288	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1124991009289	CoA-binding site [chemical binding]; other site
1124991009290	ATP-binding [chemical binding]; other site
1124991009291	hypothetical protein; Provisional; Region: PRK05287
1124991009292	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1124991009293	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1124991009294	active site
1124991009295	8-oxo-dGMP binding site [chemical binding]; other site
1124991009296	nudix motif; other site
1124991009297	metal binding site [ion binding]; metal-binding site
1124991009298	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1124991009299	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1124991009300	SEC-C motif; Region: SEC-C; pfam02810
1124991009301	Secretion monitor precursor protein (SecM); Region: SecM; cl11636
1124991009302	Protein of unknown function (DUF721); Region: DUF721; cl02324
1124991009303	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1124991009304	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1124991009305	cell division protein FtsZ; Validated; Region: PRK09330
1124991009306	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1124991009307	nucleotide binding site [chemical binding]; other site
1124991009308	SulA interaction site; other site
1124991009309	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1124991009310	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1124991009311	Cell division protein FtsA; Region: FtsA; pfam14450
1124991009312	cell division protein FtsQ; Provisional; Region: PRK10775
1124991009313	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1124991009314	Cell division protein FtsQ; Region: FtsQ; pfam03799
1124991009315	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1124991009316	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1124991009317	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1124991009318	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1124991009319	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1124991009320	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991009321	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991009322	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1124991009323	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1124991009324	active site
1124991009325	homodimer interface [polypeptide binding]; other site
1124991009326	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1124991009327	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1124991009328	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991009329	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991009330	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1124991009331	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1124991009332	Mg++ binding site [ion binding]; other site
1124991009333	putative catalytic motif [active]
1124991009334	putative substrate binding site [chemical binding]; other site
1124991009335	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1124991009336	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1124991009337	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991009338	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991009339	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1124991009340	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1124991009341	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1124991009342	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1124991009343	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1124991009344	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1124991009345	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1124991009346	cell division protein FtsL; Provisional; Region: PRK10772
1124991009347	MraW methylase family; Region: Methyltransf_5; pfam01795
1124991009348	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1124991009349	cell division protein MraZ; Reviewed; Region: PRK00326
1124991009350	MraZ protein; Region: MraZ; pfam02381
1124991009351	MraZ protein; Region: MraZ; pfam02381
1124991009352	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1124991009353	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991009354	DNA binding site [nucleotide binding]
1124991009355	domain linker motif; other site
1124991009356	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1124991009357	dimerization interface [polypeptide binding]; other site
1124991009358	ligand binding site [chemical binding]; other site
1124991009359	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1124991009360	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1124991009361	putative valine binding site [chemical binding]; other site
1124991009362	dimer interface [polypeptide binding]; other site
1124991009363	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1124991009364	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1124991009365	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1124991009366	PYR/PP interface [polypeptide binding]; other site
1124991009367	dimer interface [polypeptide binding]; other site
1124991009368	TPP binding site [chemical binding]; other site
1124991009369	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991009370	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1124991009371	TPP-binding site [chemical binding]; other site
1124991009372	dimer interface [polypeptide binding]; other site
1124991009373	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1124991009374	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1124991009375	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1124991009376	acyl-activating enzyme (AAE) consensus motif; other site
1124991009377	acyl-activating enzyme (AAE) consensus motif; other site
1124991009378	putative AMP binding site [chemical binding]; other site
1124991009379	putative active site [active]
1124991009380	putative CoA binding site [chemical binding]; other site
1124991009381	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1124991009382	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991009383	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991009384	dimerization interface [polypeptide binding]; other site
1124991009385	2-isopropylmalate synthase; Validated; Region: PRK00915
1124991009386	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1124991009387	active site
1124991009388	catalytic residues [active]
1124991009389	metal binding site [ion binding]; metal-binding site
1124991009390	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1124991009391	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1124991009392	tartrate dehydrogenase; Region: TTC; TIGR02089
1124991009393	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1124991009394	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1124991009395	substrate binding site [chemical binding]; other site
1124991009396	ligand binding site [chemical binding]; other site
1124991009397	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1124991009398	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1124991009399	substrate binding site [chemical binding]; other site
1124991009400	transcriptional regulator SgrR; Provisional; Region: PRK13626
1124991009401	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1124991009402	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1124991009403	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1124991009404	putative DNA-binding cleft [nucleotide binding]; other site
1124991009405	putative DNA clevage site; other site
1124991009406	molecular lever; other site
1124991009407	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1124991009408	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1124991009409	catalytic core [active]
1124991009410	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1124991009411	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1124991009412	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1124991009413	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1124991009414	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1124991009415	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
1124991009416	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
1124991009417	putative deacylase active site [active]
1124991009418	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1124991009419	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991009420	DNA-binding site [nucleotide binding]; DNA binding site
1124991009421	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991009422	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991009423	homodimer interface [polypeptide binding]; other site
1124991009424	catalytic residue [active]
1124991009425	Pirin-related protein [General function prediction only]; Region: COG1741
1124991009426	Pirin; Region: Pirin; pfam02678
1124991009427	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1124991009428	Fic family protein [Function unknown]; Region: COG3177
1124991009429	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
1124991009430	Fic/DOC family; Region: Fic; pfam02661
1124991009431	LysR family transcriptional regulator; Provisional; Region: PRK14997
1124991009432	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991009433	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1124991009434	putative effector binding pocket; other site
1124991009435	putative dimerization interface [polypeptide binding]; other site
1124991009436	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1124991009437	acetoin reductases; Region: 23BDH; TIGR02415
1124991009438	NAD binding site [chemical binding]; other site
1124991009439	homotetramer interface [polypeptide binding]; other site
1124991009440	homodimer interface [polypeptide binding]; other site
1124991009441	active site
1124991009442	substrate binding site [chemical binding]; other site
1124991009443	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1124991009444	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991009445	DNA binding site [nucleotide binding]
1124991009446	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1124991009447	dimerization interface (closed form) [polypeptide binding]; other site
1124991009448	ligand binding site [chemical binding]; other site
1124991009449	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1124991009450	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1124991009451	ligand binding site [chemical binding]; other site
1124991009452	calcium binding site [ion binding]; other site
1124991009453	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1124991009454	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1124991009455	Walker A/P-loop; other site
1124991009456	ATP binding site [chemical binding]; other site
1124991009457	Q-loop/lid; other site
1124991009458	ABC transporter signature motif; other site
1124991009459	Walker B; other site
1124991009460	D-loop; other site
1124991009461	H-loop/switch region; other site
1124991009462	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1124991009463	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991009464	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991009465	TM-ABC transporter signature motif; other site
1124991009466	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1124991009467	agmatinase; Region: agmatinase; TIGR01230
1124991009468	oligomer interface [polypeptide binding]; other site
1124991009469	putative active site [active]
1124991009470	Mn binding site [ion binding]; other site
1124991009471	arginine decarboxylase; Provisional; Region: PRK05354
1124991009472	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1124991009473	dimer interface [polypeptide binding]; other site
1124991009474	active site
1124991009475	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1124991009476	catalytic residues [active]
1124991009477	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1124991009478	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1124991009479	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1124991009480	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1124991009481	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1124991009482	Predicted transporter component [General function prediction only]; Region: COG2391
1124991009483	Sulphur transport; Region: Sulf_transp; pfam04143
1124991009484	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
1124991009485	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991009486	dimerization interface [polypeptide binding]; other site
1124991009487	putative DNA binding site [nucleotide binding]; other site
1124991009488	putative Zn2+ binding site [ion binding]; other site
1124991009489	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1124991009490	hypothetical protein; Provisional; Region: PRK04860
1124991009491	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1124991009492	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1124991009493	Divalent cation transporter; Region: MgtE; pfam01769
1124991009494	SnoaL-like domain; Region: SnoaL_2; pfam12680
1124991009495	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1124991009496	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1124991009497	FAD binding pocket [chemical binding]; other site
1124991009498	FAD binding motif [chemical binding]; other site
1124991009499	phosphate binding motif [ion binding]; other site
1124991009500	beta-alpha-beta structure motif; other site
1124991009501	NAD binding pocket [chemical binding]; other site
1124991009502	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1124991009503	catalytic loop [active]
1124991009504	iron binding site [ion binding]; other site
1124991009505	hybrid cluster protein; Provisional; Region: PRK05290
1124991009506	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1124991009507	ACS interaction site; other site
1124991009508	CODH interaction site; other site
1124991009509	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1124991009510	hybrid metal cluster; other site
1124991009511	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1124991009512	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991009513	N-terminal plug; other site
1124991009514	ligand-binding site [chemical binding]; other site
1124991009515	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1124991009516	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1124991009517	putative ligand binding residues [chemical binding]; other site
1124991009518	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1124991009519	amino acid carrier protein; Region: agcS; TIGR00835
1124991009520	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1124991009521	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1124991009522	Cl- selectivity filter; other site
1124991009523	Cl- binding residues [ion binding]; other site
1124991009524	pore gating glutamate residue; other site
1124991009525	dimer interface [polypeptide binding]; other site
1124991009526	H+/Cl- coupling transport residue; other site
1124991009527	tellurite resistance protein TehB; Provisional; Region: PRK12335
1124991009528	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
1124991009529	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991009530	S-adenosylmethionine binding site [chemical binding]; other site
1124991009531	Choloylglycine hydrolase (CGH) is a bile salt-modifying enzyme that hydrolyzes non-peptide carbon-nitrogen bonds in choloylglycine and choloyltaurine, both of which are present in bile.  CGH is present in a number of probiotic microbial organisms that...; Region: Ntn_CGH; cd01902
1124991009532	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1124991009533	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1124991009534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991009535	putative substrate translocation pore; other site
1124991009536	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991009537	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1124991009538	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991009539	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991009540	YceI-like domain; Region: YceI; cl01001
1124991009541	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1124991009542	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1124991009543	active site
1124991009544	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991009545	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991009546	non-specific DNA binding site [nucleotide binding]; other site
1124991009547	salt bridge; other site
1124991009548	sequence-specific DNA binding site [nucleotide binding]; other site
1124991009549	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1124991009550	Phosphotransferase enzyme family; Region: APH; pfam01636
1124991009551	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1124991009552	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1124991009553	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1124991009554	intersubunit interface [polypeptide binding]; other site
1124991009555	active site
1124991009556	Zn2+ binding site [ion binding]; other site
1124991009557	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1124991009558	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991009559	sequence-specific DNA binding site [nucleotide binding]; other site
1124991009560	salt bridge; other site
1124991009561	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1124991009562	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1124991009563	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1124991009564	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991009565	FeS/SAM binding site; other site
1124991009566	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1124991009567	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991009568	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991009569	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1124991009570	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1124991009571	Walker A/P-loop; other site
1124991009572	ATP binding site [chemical binding]; other site
1124991009573	Q-loop/lid; other site
1124991009574	ABC transporter signature motif; other site
1124991009575	Walker B; other site
1124991009576	D-loop; other site
1124991009577	H-loop/switch region; other site
1124991009578	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1124991009579	Walker A/P-loop; other site
1124991009580	ATP binding site [chemical binding]; other site
1124991009581	Q-loop/lid; other site
1124991009582	ABC transporter signature motif; other site
1124991009583	Walker B; other site
1124991009584	D-loop; other site
1124991009585	H-loop/switch region; other site
1124991009586	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1124991009587	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991009588	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1124991009589	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1124991009590	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1124991009591	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1124991009592	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1124991009593	DNA binding site [nucleotide binding]
1124991009594	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1124991009595	dimerization interface [polypeptide binding]; other site
1124991009596	ligand binding site [chemical binding]; other site
1124991009597	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1124991009598	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1124991009599	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1124991009600	inhibitor binding site; inhibition site
1124991009601	catalytic Zn binding site [ion binding]; other site
1124991009602	structural Zn binding site [ion binding]; other site
1124991009603	NADP binding site [chemical binding]; other site
1124991009604	tetramer interface [polypeptide binding]; other site
1124991009605	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
1124991009606	N- and C-terminal domain interface [polypeptide binding]; other site
1124991009607	D-xylulose kinase; Region: XylB; TIGR01312
1124991009608	active site
1124991009609	MgATP binding site [chemical binding]; other site
1124991009610	catalytic site [active]
1124991009611	metal binding site [ion binding]; metal-binding site
1124991009612	xylulose binding site [chemical binding]; other site
1124991009613	putative homodimer interface [polypeptide binding]; other site
1124991009614	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1124991009615	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1124991009616	Walker A/P-loop; other site
1124991009617	ATP binding site [chemical binding]; other site
1124991009618	Q-loop/lid; other site
1124991009619	ABC transporter signature motif; other site
1124991009620	Walker B; other site
1124991009621	D-loop; other site
1124991009622	H-loop/switch region; other site
1124991009623	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1124991009624	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991009625	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1124991009626	TM-ABC transporter signature motif; other site
1124991009627	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1124991009628	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
1124991009629	putative ligand binding site [chemical binding]; other site
1124991009630	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1124991009631	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991009632	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991009633	dimerization interface [polypeptide binding]; other site
1124991009634	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1124991009635	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1124991009636	dimer interface [polypeptide binding]; other site
1124991009637	PYR/PP interface [polypeptide binding]; other site
1124991009638	TPP binding site [chemical binding]; other site
1124991009639	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1124991009640	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1124991009641	TPP-binding site [chemical binding]; other site
1124991009642	dimer interface [polypeptide binding]; other site
1124991009643	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
1124991009644	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1124991009645	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1124991009646	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
1124991009647	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1124991009648	active site
1124991009649	phosphorylation site [posttranslational modification]
1124991009650	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1124991009651	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1124991009652	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1124991009653	active pocket/dimerization site; other site
1124991009654	active site
1124991009655	phosphorylation site [posttranslational modification]
1124991009656	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1124991009657	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1124991009658	active site
1124991009659	dimer interface [polypeptide binding]; other site
1124991009660	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1124991009661	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1124991009662	dimer interface [polypeptide binding]; other site
1124991009663	active site
1124991009664	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1124991009665	putative active site [active]
1124991009666	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1124991009667	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1124991009668	intersubunit interface [polypeptide binding]; other site
1124991009669	active site
1124991009670	zinc binding site [ion binding]; other site
1124991009671	Na+ binding site [ion binding]; other site
1124991009672	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1124991009673	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1124991009674	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1124991009675	active site turn [active]
1124991009676	phosphorylation site [posttranslational modification]
1124991009677	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1124991009678	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1124991009679	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1124991009680	homodimer interface [polypeptide binding]; other site
1124991009681	catalytic residue [active]
1124991009682	xanthine permease; Region: pbuX; TIGR03173
1124991009683	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
1124991009684	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991009685	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991009686	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1124991009687	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1124991009688	Nucleoside recognition; Region: Gate; pfam07670
1124991009689	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1124991009690	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1124991009691	putative kinase; Provisional; Region: PRK09954
1124991009692	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991009693	putative DNA binding site [nucleotide binding]; other site
1124991009694	putative Zn2+ binding site [ion binding]; other site
1124991009695	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1124991009696	substrate binding site [chemical binding]; other site
1124991009697	ATP binding site [chemical binding]; other site
1124991009698	YodA lipocalin-like domain; Region: YodA; cl01365
1124991009699	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1124991009700	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1124991009701	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1124991009702	CHAP domain; Region: CHAP; pfam05257
1124991009703	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1124991009704	xanthine permease; Region: pbuX; TIGR03173
1124991009705	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1124991009706	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1124991009707	NAD binding site [chemical binding]; other site
1124991009708	substrate binding site [chemical binding]; other site
1124991009709	catalytic Zn binding site [ion binding]; other site
1124991009710	tetramer interface [polypeptide binding]; other site
1124991009711	structural Zn binding site [ion binding]; other site
1124991009712	Pirin-related protein [General function prediction only]; Region: COG1741
1124991009713	Pirin; Region: Pirin; pfam02678
1124991009714	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1124991009715	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1124991009716	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1124991009717	putative active site [active]
1124991009718	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991009719	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1124991009720	Walker A/P-loop; other site
1124991009721	ATP binding site [chemical binding]; other site
1124991009722	Q-loop/lid; other site
1124991009723	ABC transporter signature motif; other site
1124991009724	Walker B; other site
1124991009725	D-loop; other site
1124991009726	H-loop/switch region; other site
1124991009727	HlyD family secretion protein; Region: HlyD; pfam00529
1124991009728	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991009729	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991009730	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1124991009731	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1124991009732	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1124991009733	NADP binding site [chemical binding]; other site
1124991009734	dimer interface [polypeptide binding]; other site
1124991009735	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991009736	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991009737	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1124991009738	ArsC family; Region: ArsC; pfam03960
1124991009739	catalytic residues [active]
1124991009740	arsenical pump membrane protein; Provisional; Region: PRK15445
1124991009741	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1124991009742	transmembrane helices; other site
1124991009743	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
1124991009744	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1124991009745	P loop; other site
1124991009746	Nucleotide binding site [chemical binding]; other site
1124991009747	DTAP/Switch II; other site
1124991009748	Switch I; other site
1124991009749	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1124991009750	P loop; other site
1124991009751	Nucleotide binding site [chemical binding]; other site
1124991009752	DTAP/Switch II; other site
1124991009753	Switch I; other site
1124991009754	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
1124991009755	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991009756	dimerization interface [polypeptide binding]; other site
1124991009757	putative DNA binding site [nucleotide binding]; other site
1124991009758	putative Zn2+ binding site [ion binding]; other site
1124991009759	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1124991009760	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1124991009761	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1124991009762	homodimer interface [polypeptide binding]; other site
1124991009763	NADP binding site [chemical binding]; other site
1124991009764	substrate binding site [chemical binding]; other site
1124991009765	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1124991009766	RNA binding surface [nucleotide binding]; other site
1124991009767	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1124991009768	Cytochrome b562; Region: Cytochrom_B562; cl01546
1124991009769	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1124991009770	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1124991009771	active site
1124991009772	HIGH motif; other site
1124991009773	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1124991009774	KMSKS motif; other site
1124991009775	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1124991009776	tRNA binding surface [nucleotide binding]; other site
1124991009777	anticodon binding site; other site
1124991009778	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1124991009779	substrate binding site [chemical binding]; other site
1124991009780	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1124991009781	putative active site [active]
1124991009782	putative metal binding site [ion binding]; other site
1124991009783	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1124991009784	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1124991009785	ATP-grasp domain; Region: ATP-grasp; pfam02222
1124991009786	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991009787	putative substrate translocation pore; other site
1124991009788	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1124991009789	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1124991009790	FtsX-like permease family; Region: FtsX; pfam02687
1124991009791	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1124991009792	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1124991009793	Walker A/P-loop; other site
1124991009794	ATP binding site [chemical binding]; other site
1124991009795	Q-loop/lid; other site
1124991009796	ABC transporter signature motif; other site
1124991009797	Walker B; other site
1124991009798	D-loop; other site
1124991009799	H-loop/switch region; other site
1124991009800	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1124991009801	active site
1124991009802	catalytic triad [active]
1124991009803	oxyanion hole [active]
1124991009804	switch loop; other site
1124991009805	oxidoreductase; Provisional; Region: PRK08017
1124991009806	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1124991009807	NADP binding site [chemical binding]; other site
1124991009808	active site
1124991009809	steroid binding site; other site
1124991009810	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1124991009811	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1124991009812	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1124991009813	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1124991009814	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1124991009815	Peptidase family C69; Region: Peptidase_C69; cl17793
1124991009816	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1124991009817	RelB antitoxin; Region: RelB; cl01171
1124991009818	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1124991009819	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009820	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009821	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009822	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009823	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009824	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1124991009825	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1124991009826	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1124991009827	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1124991009828	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1124991009829	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1124991009830	DNA binding residues [nucleotide binding]
1124991009831	dimer interface [polypeptide binding]; other site
1124991009832	copper binding site [ion binding]; other site
1124991009833	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1124991009834	metal-binding site [ion binding]
1124991009835	copper exporting ATPase; Provisional; Region: copA; PRK10671
1124991009836	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1124991009837	metal-binding site [ion binding]
1124991009838	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1124991009839	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991009840	motif II; other site
1124991009841	TraB family; Region: TraB; cl12050
1124991009842	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1124991009843	putative deacylase active site [active]
1124991009844	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1124991009845	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1124991009846	type III secretion protein GogB; Provisional; Region: PRK15386
1124991009847	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1124991009848	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1124991009849	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1124991009850	active site
1124991009851	metal binding site [ion binding]; metal-binding site
1124991009852	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1124991009853	putative cation:proton antiport protein; Provisional; Region: PRK10669
1124991009854	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1124991009855	TrkA-N domain; Region: TrkA_N; pfam02254
1124991009856	inosine/guanosine kinase; Provisional; Region: PRK15074
1124991009857	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1124991009858	substrate binding site [chemical binding]; other site
1124991009859	ATP binding site [chemical binding]; other site
1124991009860	Chain length determinant protein [Cell envelope biogenesis, outer membrane]; Region: WzzB; COG3765
1124991009861	Chain length determinant protein; Region: Wzz; pfam02706
1124991009862	ferrochelatase; Reviewed; Region: hemH; PRK00035
1124991009863	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1124991009864	C-terminal domain interface [polypeptide binding]; other site
1124991009865	active site
1124991009866	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1124991009867	active site
1124991009868	N-terminal domain interface [polypeptide binding]; other site
1124991009869	adenylate kinase; Reviewed; Region: adk; PRK00279
1124991009870	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1124991009871	AMP-binding site [chemical binding]; other site
1124991009872	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1124991009873	heat shock protein 90; Provisional; Region: PRK05218
1124991009874	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991009875	ATP binding site [chemical binding]; other site
1124991009876	Mg2+ binding site [ion binding]; other site
1124991009877	G-X-G motif; other site
1124991009878	recombination protein RecR; Reviewed; Region: recR; PRK00076
1124991009879	RecR protein; Region: RecR; pfam02132
1124991009880	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1124991009881	putative active site [active]
1124991009882	putative metal-binding site [ion binding]; other site
1124991009883	tetramer interface [polypeptide binding]; other site
1124991009884	hypothetical protein; Validated; Region: PRK00153
1124991009885	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1124991009886	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991009887	Walker A motif; other site
1124991009888	ATP binding site [chemical binding]; other site
1124991009889	Walker B motif; other site
1124991009890	arginine finger; other site
1124991009891	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1124991009892	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1124991009893	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1124991009894	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1124991009895	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1124991009896	active site
1124991009897	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
1124991009898	hypothetical protein; Provisional; Region: PRK11038
1124991009899	hypothetical protein; Provisional; Region: PRK11281
1124991009900	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1124991009901	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1124991009902	DsrE/DsrF-like family; Region: DrsE; cl00672
1124991009903	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1124991009904	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991009905	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1124991009906	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1124991009907	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1124991009908	HlyD family secretion protein; Region: HlyD_3; pfam13437
1124991009909	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1124991009910	Protein export membrane protein; Region: SecD_SecF; cl14618
1124991009911	Protein export membrane protein; Region: SecD_SecF; cl14618
1124991009912	Biofilm formation regulator YbaJ; Region: YbaJ; cl11675
1124991009913	gene expression modulator; Provisional; Region: PRK10945
1124991009914	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1124991009915	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1124991009916	active site
1124991009917	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1124991009918	catalytic triad [active]
1124991009919	dimer interface [polypeptide binding]; other site
1124991009920	ammonium transporter; Provisional; Region: PRK10666
1124991009921	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
1124991009922	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1124991009923	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1124991009924	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991009925	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991009926	Walker A/P-loop; other site
1124991009927	ATP binding site [chemical binding]; other site
1124991009928	Q-loop/lid; other site
1124991009929	ABC transporter signature motif; other site
1124991009930	Walker B; other site
1124991009931	D-loop; other site
1124991009932	H-loop/switch region; other site
1124991009933	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1124991009934	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1124991009935	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991009936	Walker A/P-loop; other site
1124991009937	ATP binding site [chemical binding]; other site
1124991009938	Q-loop/lid; other site
1124991009939	ABC transporter signature motif; other site
1124991009940	Walker B; other site
1124991009941	D-loop; other site
1124991009942	H-loop/switch region; other site
1124991009943	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1124991009944	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1124991009945	putative DNA binding site [nucleotide binding]; other site
1124991009946	putative Zn2+ binding site [ion binding]; other site
1124991009947	AsnC family; Region: AsnC_trans_reg; pfam01037
1124991009948	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1124991009949	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1124991009950	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991009951	catalytic residue [active]
1124991009952	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1124991009953	Ligand Binding Site [chemical binding]; other site
1124991009954	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1124991009955	active site
1124991009956	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1124991009957	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1124991009958	periplasmic folding chaperone; Provisional; Region: PRK10788
1124991009959	SurA N-terminal domain; Region: SurA_N_3; cl07813
1124991009960	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1124991009961	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1124991009962	IHF dimer interface [polypeptide binding]; other site
1124991009963	IHF - DNA interface [nucleotide binding]; other site
1124991009964	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1124991009965	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1124991009966	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991009967	Walker A motif; other site
1124991009968	ATP binding site [chemical binding]; other site
1124991009969	Walker B motif; other site
1124991009970	arginine finger; other site
1124991009971	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1124991009972	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1124991009973	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1124991009974	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991009975	Walker A motif; other site
1124991009976	ATP binding site [chemical binding]; other site
1124991009977	Walker B motif; other site
1124991009978	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1124991009979	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1124991009980	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1124991009981	oligomer interface [polypeptide binding]; other site
1124991009982	active site residues [active]
1124991009983	trigger factor; Provisional; Region: tig; PRK01490
1124991009984	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1124991009985	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1124991009986	BolA-like protein; Region: BolA; cl00386
1124991009987	hypothetical protein; Provisional; Region: PRK11627
1124991009988	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1124991009989	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1124991009990	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991009991	putative substrate translocation pore; other site
1124991009992	hypothetical protein; Provisional; Region: PRK11528
1124991009993	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1124991009994	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1124991009995	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1124991009996	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1124991009997	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1124991009998	D-pathway; other site
1124991009999	Putative ubiquinol binding site [chemical binding]; other site
1124991010000	Low-spin heme (heme b) binding site [chemical binding]; other site
1124991010001	Putative water exit pathway; other site
1124991010002	Binuclear center (heme o3/CuB) [ion binding]; other site
1124991010003	K-pathway; other site
1124991010004	Putative proton exit pathway; other site
1124991010005	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1124991010006	Subunit I/III interface [polypeptide binding]; other site
1124991010007	Subunit III/IV interface [polypeptide binding]; other site
1124991010008	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1124991010009	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1124991010010	UbiA prenyltransferase family; Region: UbiA; pfam01040
1124991010011	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991010012	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1124991010013	putative substrate translocation pore; other site
1124991010014	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1124991010015	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1124991010016	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1124991010017	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1124991010018	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1124991010019	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1124991010020	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1124991010021	conserved cys residue [active]
1124991010022	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1124991010023	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1124991010024	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1124991010025	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1124991010026	Ligand Binding Site [chemical binding]; other site
1124991010027	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1124991010028	active site residue [active]
1124991010029	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1124991010030	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1124991010031	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1124991010032	substrate binding pocket [chemical binding]; other site
1124991010033	chain length determination region; other site
1124991010034	substrate-Mg2+ binding site; other site
1124991010035	catalytic residues [active]
1124991010036	aspartate-rich region 1; other site
1124991010037	active site lid residues [active]
1124991010038	aspartate-rich region 2; other site
1124991010039	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1124991010040	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1124991010041	TPP-binding site; other site
1124991010042	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1124991010043	PYR/PP interface [polypeptide binding]; other site
1124991010044	dimer interface [polypeptide binding]; other site
1124991010045	TPP binding site [chemical binding]; other site
1124991010046	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1124991010047	thiamine monophosphate kinase; Provisional; Region: PRK05731
1124991010048	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1124991010049	ATP binding site [chemical binding]; other site
1124991010050	dimerization interface [polypeptide binding]; other site
1124991010051	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1124991010052	putative RNA binding site [nucleotide binding]; other site
1124991010053	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1124991010054	homopentamer interface [polypeptide binding]; other site
1124991010055	active site
1124991010056	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1124991010057	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1124991010058	catalytic motif [active]
1124991010059	Zn binding site [ion binding]; other site
1124991010060	RibD C-terminal domain; Region: RibD_C; cl17279
1124991010061	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1124991010062	ATP cone domain; Region: ATP-cone; pfam03477
1124991010063	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1124991010064	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1124991010065	Protein export membrane protein; Region: SecD_SecF; pfam02355
1124991010066	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1124991010067	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1124991010068	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1124991010069	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1124991010070	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1124991010071	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1124991010072	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1124991010073	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1124991010074	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1124991010075	Protein of unknown function, DUF479; Region: DUF479; cl01203
1124991010076	peroxidase; Provisional; Region: PRK15000
1124991010077	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1124991010078	dimer interface [polypeptide binding]; other site
1124991010079	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1124991010080	catalytic triad [active]
1124991010081	peroxidatic and resolving cysteines [active]
1124991010082	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1124991010083	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1124991010084	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1124991010085	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1124991010086	putative active site [active]
1124991010087	heme pocket [chemical binding]; other site
1124991010088	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991010089	dimer interface [polypeptide binding]; other site
1124991010090	phosphorylation site [posttranslational modification]
1124991010091	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991010092	ATP binding site [chemical binding]; other site
1124991010093	Mg2+ binding site [ion binding]; other site
1124991010094	G-X-G motif; other site
1124991010095	transcriptional regulator PhoB; Provisional; Region: PRK10161
1124991010096	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991010097	active site
1124991010098	phosphorylation site [posttranslational modification]
1124991010099	intermolecular recognition site; other site
1124991010100	dimerization interface [polypeptide binding]; other site
1124991010101	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991010102	DNA binding site [nucleotide binding]
1124991010103	exonuclease subunit SbcD; Provisional; Region: PRK10966
1124991010104	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1124991010105	active site
1124991010106	metal binding site [ion binding]; metal-binding site
1124991010107	DNA binding site [nucleotide binding]
1124991010108	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1124991010109	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991010110	Walker A/P-loop; other site
1124991010111	ATP binding site [chemical binding]; other site
1124991010112	Q-loop/lid; other site
1124991010113	exonuclease subunit SbcC; Provisional; Region: PRK10246
1124991010114	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991010115	ABC transporter signature motif; other site
1124991010116	Walker B; other site
1124991010117	D-loop; other site
1124991010118	H-loop/switch region; other site
1124991010119	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1124991010120	dimer interface [polypeptide binding]; other site
1124991010121	FMN binding site [chemical binding]; other site
1124991010122	fructokinase; Reviewed; Region: PRK09557
1124991010123	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1124991010124	nucleotide binding site [chemical binding]; other site
1124991010125	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1124991010126	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1124991010127	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1124991010128	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1124991010129	CPxP  motif; other site
1124991010130	putative inner membrane protein; Provisional; Region: PRK11099
1124991010131	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1124991010132	dimerization interface [polypeptide binding]; other site
1124991010133	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1124991010134	ATP binding site [chemical binding]; other site
1124991010135	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1124991010136	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1124991010137	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1124991010138	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1124991010139	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1124991010140	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1124991010141	homooctamer interface [polypeptide binding]; other site
1124991010142	active site
1124991010143	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1124991010144	UGMP family protein; Validated; Region: PRK09604
1124991010145	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1124991010146	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1124991010147	DNA primase; Validated; Region: dnaG; PRK05667
1124991010148	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1124991010149	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1124991010150	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1124991010151	active site
1124991010152	metal binding site [ion binding]; metal-binding site
1124991010153	interdomain interaction site; other site
1124991010154	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1124991010155	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1124991010156	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1124991010157	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1124991010158	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1124991010159	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1124991010160	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991010161	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1124991010162	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991010163	DNA binding residues [nucleotide binding]
1124991010164	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991010165	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991010166	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991010167	Sel1-like repeats; Region: SEL1; smart00671
1124991010168	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991010169	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
1124991010170	Transglycosylase; Region: Transgly; pfam00912
1124991010171	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1124991010172	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1124991010173	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like; cl17506
1124991010174	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1124991010175	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1124991010176	MG2 domain; Region: A2M_N; pfam01835
1124991010177	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1124991010178	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1124991010179	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1124991010180	surface patch; other site
1124991010181	thioester region; other site
1124991010182	specificity defining residues; other site
1124991010183	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1124991010184	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1124991010185	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1124991010186	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991010187	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991010188	dimerization interface [polypeptide binding]; other site
1124991010189	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1124991010190	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1124991010191	Protein of unknown function (DUF3457); Region: DUF3457; cl08122
1124991010192	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1124991010193	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1124991010194	putative substrate-binding site; other site
1124991010195	nickel binding site [ion binding]; other site
1124991010196	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1124991010197	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1124991010198	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1124991010199	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1124991010200	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1124991010201	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1124991010202	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1124991010203	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1124991010204	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1124991010205	Na2 binding site [ion binding]; other site
1124991010206	putative substrate binding site 1 [chemical binding]; other site
1124991010207	Na binding site 1 [ion binding]; other site
1124991010208	putative substrate binding site 2 [chemical binding]; other site
1124991010209	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
1124991010210	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991010211	catalytic residue [active]
1124991010212	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1124991010213	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1124991010214	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1124991010215	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1124991010216	Predicted membrane protein [Function unknown]; Region: COG5393
1124991010217	YqjK-like protein; Region: YqjK; pfam13997
1124991010218	Predicted membrane protein [Function unknown]; Region: COG2259
1124991010219	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1124991010220	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1124991010221	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1124991010222	dimerization interface [polypeptide binding]; other site
1124991010223	Pirin-related protein [General function prediction only]; Region: COG1741
1124991010224	Pirin; Region: Pirin; pfam02678
1124991010225	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1124991010226	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1124991010227	putative SAM binding site [chemical binding]; other site
1124991010228	putative homodimer interface [polypeptide binding]; other site
1124991010229	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1124991010230	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1124991010231	putative ligand binding site [chemical binding]; other site
1124991010232	hypothetical protein; Reviewed; Region: PRK12497
1124991010233	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1124991010234	dimer interface [polypeptide binding]; other site
1124991010235	active site
1124991010236	outer membrane lipoprotein; Provisional; Region: PRK11023
1124991010237	BON domain; Region: BON; pfam04972
1124991010238	BON domain; Region: BON; pfam04972
1124991010239	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1124991010240	Transglycosylase; Region: Transgly; cl17702
1124991010241	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1124991010242	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1124991010243	conserved cys residue [active]
1124991010244	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1124991010245	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1124991010246	putative active site [active]
1124991010247	heme pocket [chemical binding]; other site
1124991010248	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991010249	dimer interface [polypeptide binding]; other site
1124991010250	phosphorylation site [posttranslational modification]
1124991010251	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991010252	ATP binding site [chemical binding]; other site
1124991010253	Mg2+ binding site [ion binding]; other site
1124991010254	G-X-G motif; other site
1124991010255	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991010256	active site
1124991010257	phosphorylation site [posttranslational modification]
1124991010258	intermolecular recognition site; other site
1124991010259	dimerization interface [polypeptide binding]; other site
1124991010260	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1124991010261	putative binding surface; other site
1124991010262	active site
1124991010263	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1124991010264	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1124991010265	active site
1124991010266	dimer interface [polypeptide binding]; other site
1124991010267	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1124991010268	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1124991010269	active site
1124991010270	FMN binding site [chemical binding]; other site
1124991010271	substrate binding site [chemical binding]; other site
1124991010272	3Fe-4S cluster binding site [ion binding]; other site
1124991010273	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1124991010274	domain interface; other site
1124991010275	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1124991010276	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1124991010277	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1124991010278	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1124991010279	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1124991010280	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1124991010281	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1124991010282	C-terminal domain interface [polypeptide binding]; other site
1124991010283	putative GSH binding site (G-site) [chemical binding]; other site
1124991010284	dimer interface [polypeptide binding]; other site
1124991010285	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1124991010286	dimer interface [polypeptide binding]; other site
1124991010287	N-terminal domain interface [polypeptide binding]; other site
1124991010288	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1124991010289	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1124991010290	23S rRNA interface [nucleotide binding]; other site
1124991010291	L3 interface [polypeptide binding]; other site
1124991010292	Predicted ATPase [General function prediction only]; Region: COG1485
1124991010293	hypothetical protein; Provisional; Region: PRK11677
1124991010294	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1124991010295	serine endoprotease; Provisional; Region: PRK10139
1124991010296	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1124991010297	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1124991010298	protein binding site [polypeptide binding]; other site
1124991010299	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1124991010300	sulfite reductase subunit beta; Provisional; Region: PRK13504
1124991010301	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1124991010302	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1124991010303	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1124991010304	Flavodoxin; Region: Flavodoxin_1; pfam00258
1124991010305	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1124991010306	FAD binding pocket [chemical binding]; other site
1124991010307	FAD binding motif [chemical binding]; other site
1124991010308	catalytic residues [active]
1124991010309	NAD binding pocket [chemical binding]; other site
1124991010310	phosphate binding motif [ion binding]; other site
1124991010311	beta-alpha-beta structure motif; other site
1124991010312	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1124991010313	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1124991010314	substrate binding pocket [chemical binding]; other site
1124991010315	membrane-bound complex binding site; other site
1124991010316	ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG4525
1124991010317	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1124991010318	Walker A/P-loop; other site
1124991010319	ATP binding site [chemical binding]; other site
1124991010320	Q-loop/lid; other site
1124991010321	ABC transporter signature motif; other site
1124991010322	Walker B; other site
1124991010323	D-loop; other site
1124991010324	H-loop/switch region; other site
1124991010325	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1124991010326	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991010327	dimer interface [polypeptide binding]; other site
1124991010328	conserved gate region; other site
1124991010329	ABC-ATPase subunit interface; other site
1124991010330	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
1124991010331	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1124991010332	serine endoprotease; Provisional; Region: PRK10898
1124991010333	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1124991010334	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1124991010335	protein binding site [polypeptide binding]; other site
1124991010336	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1124991010337	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1124991010338	hinge; other site
1124991010339	active site
1124991010340	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1124991010341	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1124991010342	anti sigma factor interaction site; other site
1124991010343	regulatory phosphorylation site [posttranslational modification]; other site
1124991010344	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1124991010345	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1124991010346	mce related protein; Region: MCE; pfam02470
1124991010347	conserved hypothetical integral membrane protein; Region: TIGR00056
1124991010348	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1124991010349	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1124991010350	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1124991010351	Walker A/P-loop; other site
1124991010352	ATP binding site [chemical binding]; other site
1124991010353	Q-loop/lid; other site
1124991010354	ABC transporter signature motif; other site
1124991010355	Walker B; other site
1124991010356	D-loop; other site
1124991010357	H-loop/switch region; other site
1124991010358	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1124991010359	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1124991010360	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1124991010361	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1124991010362	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1124991010363	putative active site [active]
1124991010364	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1124991010365	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1124991010366	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1124991010367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
1124991010368	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1124991010369	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1124991010370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1124991010371	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1124991010372	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1124991010373	Walker A/P-loop; other site
1124991010374	ATP binding site [chemical binding]; other site
1124991010375	Q-loop/lid; other site
1124991010376	ABC transporter signature motif; other site
1124991010377	Walker B; other site
1124991010378	D-loop; other site
1124991010379	H-loop/switch region; other site
1124991010380	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1124991010381	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1124991010382	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1124991010383	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1124991010384	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1124991010385	30S subunit binding site; other site
1124991010386	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1124991010387	active site
1124991010388	phosphorylation site [posttranslational modification]
1124991010389	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1124991010390	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1124991010391	dimerization domain swap beta strand [polypeptide binding]; other site
1124991010392	regulatory protein interface [polypeptide binding]; other site
1124991010393	active site
1124991010394	regulatory phosphorylation site [posttranslational modification]; other site
1124991010395	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1124991010396	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1124991010397	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1124991010398	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991010399	N-terminal plug; other site
1124991010400	ligand-binding site [chemical binding]; other site
1124991010401	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1124991010402	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1124991010403	putative ligand binding residues [chemical binding]; other site
1124991010404	peptidase PmbA; Provisional; Region: PRK11040
1124991010405	hypothetical protein; Provisional; Region: PRK05255
1124991010406	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1124991010407	RNAase interaction site [polypeptide binding]; other site
1124991010408	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
1124991010409	active site
1124991010410	protease TldD; Provisional; Region: tldD; PRK10735
1124991010411	nitrilase; Region: PLN02798
1124991010412	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
1124991010413	putative active site [active]
1124991010414	catalytic triad [active]
1124991010415	dimer interface [polypeptide binding]; other site
1124991010416	hypothetical protein; Provisional; Region: PRK10899
1124991010417	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1124991010418	ribonuclease G; Provisional; Region: PRK11712
1124991010419	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1124991010420	homodimer interface [polypeptide binding]; other site
1124991010421	oligonucleotide binding site [chemical binding]; other site
1124991010422	Maf-like protein; Region: Maf; pfam02545
1124991010423	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1124991010424	active site
1124991010425	dimer interface [polypeptide binding]; other site
1124991010426	rod shape-determining protein MreD; Provisional; Region: PRK11060
1124991010427	rod shape-determining protein MreC; Region: mreC; TIGR00219
1124991010428	rod shape-determining protein MreC; Region: MreC; pfam04085
1124991010429	rod shape-determining protein MreB; Provisional; Region: PRK13927
1124991010430	MreB and similar proteins; Region: MreB_like; cd10225
1124991010431	nucleotide binding site [chemical binding]; other site
1124991010432	Mg binding site [ion binding]; other site
1124991010433	putative protofilament interaction site [polypeptide binding]; other site
1124991010434	RodZ interaction site [polypeptide binding]; other site
1124991010435	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1124991010436	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1124991010437	active site
1124991010438	trimer interface [polypeptide binding]; other site
1124991010439	dimer interface [polypeptide binding]; other site
1124991010440	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1124991010441	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1124991010442	carboxyltransferase (CT) interaction site; other site
1124991010443	biotinylation site [posttranslational modification]; other site
1124991010444	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1124991010445	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1124991010446	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1124991010447	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1124991010448	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1124991010449	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1124991010450	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1124991010451	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1124991010452	FMN binding site [chemical binding]; other site
1124991010453	active site
1124991010454	catalytic residues [active]
1124991010455	substrate binding site [chemical binding]; other site
1124991010456	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1124991010457	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1124991010458	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1124991010459	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1124991010460	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1124991010461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991010462	putative substrate translocation pore; other site
1124991010463	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1124991010464	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1124991010465	N-terminal plug; other site
1124991010466	ligand-binding site [chemical binding]; other site
1124991010467	hypothetical protein; Provisional; Region: PRK08204
1124991010468	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1124991010469	active site
1124991010470	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1124991010471	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991010472	dimerization interface [polypeptide binding]; other site
1124991010473	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1124991010474	dimer interface [polypeptide binding]; other site
1124991010475	putative CheW interface [polypeptide binding]; other site
1124991010476	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1124991010477	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1124991010478	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1124991010479	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991010480	active site
1124991010481	phosphorylation site [posttranslational modification]
1124991010482	intermolecular recognition site; other site
1124991010483	dimerization interface [polypeptide binding]; other site
1124991010484	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1124991010485	DNA binding site [nucleotide binding]
1124991010486	sensor protein KdpD; Provisional; Region: PRK10490
1124991010487	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1124991010488	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1124991010489	Ligand Binding Site [chemical binding]; other site
1124991010490	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1124991010491	GAF domain; Region: GAF_3; pfam13492
1124991010492	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991010493	dimer interface [polypeptide binding]; other site
1124991010494	phosphorylation site [posttranslational modification]
1124991010495	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991010496	ATP binding site [chemical binding]; other site
1124991010497	Mg2+ binding site [ion binding]; other site
1124991010498	G-X-G motif; other site
1124991010499	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1124991010500	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1124991010501	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1124991010502	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1124991010503	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1124991010504	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1124991010505	Coenzyme A binding pocket [chemical binding]; other site
1124991010506	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1124991010507	Sel1-like repeats; Region: SEL1; smart00671
1124991010508	Sel1-like repeats; Region: SEL1; smart00671
1124991010509	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1124991010510	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1124991010511	Walker A/P-loop; other site
1124991010512	ATP binding site [chemical binding]; other site
1124991010513	Q-loop/lid; other site
1124991010514	ABC transporter signature motif; other site
1124991010515	Walker B; other site
1124991010516	D-loop; other site
1124991010517	H-loop/switch region; other site
1124991010518	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1124991010519	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1124991010520	Walker A/P-loop; other site
1124991010521	ATP binding site [chemical binding]; other site
1124991010522	Q-loop/lid; other site
1124991010523	ABC transporter signature motif; other site
1124991010524	Walker B; other site
1124991010525	D-loop; other site
1124991010526	H-loop/switch region; other site
1124991010527	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1124991010528	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1124991010529	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1124991010530	TM-ABC transporter signature motif; other site
1124991010531	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1124991010532	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1124991010533	TM-ABC transporter signature motif; other site
1124991010534	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1124991010535	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1124991010536	dimerization interface [polypeptide binding]; other site
1124991010537	ligand binding site [chemical binding]; other site
1124991010538	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1124991010539	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1124991010540	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1124991010541	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1124991010542	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1124991010543	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1124991010544	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1124991010545	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1124991010546	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1124991010547	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1124991010548	DNA binding residues [nucleotide binding]
1124991010549	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1124991010550	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1124991010551	cell division protein FtsE; Provisional; Region: PRK10908
1124991010552	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1124991010553	Walker A/P-loop; other site
1124991010554	ATP binding site [chemical binding]; other site
1124991010555	Q-loop/lid; other site
1124991010556	ABC transporter signature motif; other site
1124991010557	Walker B; other site
1124991010558	D-loop; other site
1124991010559	H-loop/switch region; other site
1124991010560	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1124991010561	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1124991010562	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1124991010563	P loop; other site
1124991010564	GTP binding site [chemical binding]; other site
1124991010565	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1124991010566	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991010567	S-adenosylmethionine binding site [chemical binding]; other site
1124991010568	Protein of unknown function (DUF1145); Region: DUF1145; cl11481
1124991010569	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1124991010570	YhhN-like protein; Region: YhhN; cl01505
1124991010571	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1124991010572	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1124991010573	metal-binding site [ion binding]
1124991010574	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1124991010575	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1124991010576	motif II; other site
1124991010577	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
1124991010578	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1124991010579	CPxP  motif; other site
1124991010580	hypothetical protein; Provisional; Region: PRK11212
1124991010581	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1124991010582	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1124991010583	dimer interface [polypeptide binding]; other site
1124991010584	active site
1124991010585	metal binding site [ion binding]; metal-binding site
1124991010586	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1124991010587	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1124991010588	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1124991010589	Cysteine-rich domain; Region: CCG; pfam02754
1124991010590	Cysteine-rich domain; Region: CCG; pfam02754
1124991010591	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1124991010592	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1124991010593	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1124991010594	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1124991010595	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1124991010596	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1124991010597	L-aspartate oxidase; Provisional; Region: PRK06175
1124991010598	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1124991010599	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1124991010600	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1124991010601	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1124991010602	D-subunit interface [polypeptide binding]; other site
1124991010603	Iron-sulfur protein interface; other site
1124991010604	proximal quinone binding site [chemical binding]; other site
1124991010605	distal quinone binding site [chemical binding]; other site
1124991010606	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1124991010607	Iron-sulfur protein interface; other site
1124991010608	proximal quinone binding site [chemical binding]; other site
1124991010609	C-subunit interface; other site
1124991010610	distal quinone binding site; other site
1124991010611	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1124991010612	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1124991010613	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1124991010614	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1124991010615	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1124991010616	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
1124991010617	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1124991010618	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991010619	Walker A motif; other site
1124991010620	ATP binding site [chemical binding]; other site
1124991010621	Walker B motif; other site
1124991010622	arginine finger; other site
1124991010623	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991010624	molybdopterin cofactor binding site; other site
1124991010625	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1124991010626	molybdopterin cofactor binding site; other site
1124991010627	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1124991010628	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1124991010629	EamA-like transporter family; Region: EamA; pfam00892
1124991010630	EamA-like transporter family; Region: EamA; pfam00892
1124991010631	carbon starvation protein A; Provisional; Region: PRK15015
1124991010632	Carbon starvation protein CstA; Region: CstA; pfam02554
1124991010633	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1124991010634	Uncharacterized small protein [Function unknown]; Region: COG2879
1124991010635	conjugal transfer protein TrbH; Provisional; Region: PRK13883
1124991010636	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1124991010637	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1124991010638	nickel binding site [ion binding]; other site
1124991010639	Formate hydrogenlyase maturation protein HycH; Region: HycH; pfam07450
1124991010640	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1124991010641	hydrogenase 4 subunit H; Validated; Region: PRK08222
1124991010642	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1124991010643	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1124991010644	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1124991010645	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1124991010646	hydrogenase 4 subunit F; Validated; Region: PRK06458
1124991010647	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991010648	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
1124991010649	hydrogenase 4 subunit D; Validated; Region: PRK06525
1124991010650	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991010651	NADH dehydrogenase; Region: NADHdh; cl00469
1124991010652	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1124991010653	hydrogenase 4 subunit B; Validated; Region: PRK06521
1124991010654	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1124991010655	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1124991010656	4Fe-4S binding domain; Region: Fer4; pfam00037
1124991010657	phosphoethanolamine transferase; Provisional; Region: PRK11560
1124991010658	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1124991010659	Sulfatase; Region: Sulfatase; pfam00884
1124991010660	elongation factor P; Validated; Region: PRK00529
1124991010661	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1124991010662	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1124991010663	RNA binding site [nucleotide binding]; other site
1124991010664	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1124991010665	RNA binding site [nucleotide binding]; other site
1124991010666	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1124991010667	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1124991010668	FeS/SAM binding site; other site
1124991010669	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1124991010670	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1124991010671	S-adenosylmethionine binding site [chemical binding]; other site
1124991010672	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1124991010673	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
1124991010674	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
1124991010675	tetramer interface [polypeptide binding]; other site
1124991010676	active site
1124991010677	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1124991010678	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1124991010679	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1124991010680	active site turn [active]
1124991010681	phosphorylation site [posttranslational modification]
1124991010682	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1124991010683	transcriptional regulator MurR; Provisional; Region: PRK15482
1124991010684	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1124991010685	putative active site [active]
1124991010686	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1124991010687	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1124991010688	ring oligomerisation interface [polypeptide binding]; other site
1124991010689	ATP/Mg binding site [chemical binding]; other site
1124991010690	stacking interactions; other site
1124991010691	hinge regions; other site
1124991010692	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1124991010693	oligomerisation interface [polypeptide binding]; other site
1124991010694	mobile loop; other site
1124991010695	roof hairpin; other site
1124991010696	phage T7 F exclusion suppressor FxsA; Reviewed; Region: fxsA; PRK11463
1124991010697	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1124991010698	Aspartase; Region: Aspartase; cd01357
1124991010699	active sites [active]
1124991010700	tetramer interface [polypeptide binding]; other site
1124991010701	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1124991010702	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1124991010703	putative transcriptional regulator; Provisional; Region: PRK11640
1124991010704	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1124991010705	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1124991010706	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991010707	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1124991010708	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991010709	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991010710	non-specific DNA binding site [nucleotide binding]; other site
1124991010711	salt bridge; other site
1124991010712	sequence-specific DNA binding site [nucleotide binding]; other site
1124991010713	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1124991010714	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
1124991010715	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991010716	Walker A/P-loop; other site
1124991010717	ATP binding site [chemical binding]; other site
1124991010718	Q-loop/lid; other site
1124991010719	ABC transporter signature motif; other site
1124991010720	Walker B; other site
1124991010721	D-loop; other site
1124991010722	H-loop/switch region; other site
1124991010723	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1124991010724	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
1124991010725	Walker A/P-loop; other site
1124991010726	ATP binding site [chemical binding]; other site
1124991010727	Q-loop/lid; other site
1124991010728	ABC transporter signature motif; other site
1124991010729	Walker B; other site
1124991010730	D-loop; other site
1124991010731	H-loop/switch region; other site
1124991010732	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1124991010733	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
1124991010734	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991010735	dimer interface [polypeptide binding]; other site
1124991010736	conserved gate region; other site
1124991010737	putative PBP binding loops; other site
1124991010738	ABC-ATPase subunit interface; other site
1124991010739	nickel transporter permease NikB; Provisional; Region: PRK10352
1124991010740	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1124991010741	dimer interface [polypeptide binding]; other site
1124991010742	conserved gate region; other site
1124991010743	putative PBP binding loops; other site
1124991010744	ABC-ATPase subunit interface; other site
1124991010745	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1124991010746	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1124991010747	substrate binding site [chemical binding]; other site
1124991010748	hypothetical protein; Provisional; Region: PRK10220
1124991010749	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1124991010750	PhnA protein; Region: PhnA; pfam03831
1124991010751	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991010752	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991010753	non-specific DNA binding site [nucleotide binding]; other site
1124991010754	salt bridge; other site
1124991010755	sequence-specific DNA binding site [nucleotide binding]; other site
1124991010756	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991010757	active site
1124991010758	DNA binding site [nucleotide binding]
1124991010759	Int/Topo IB signature motif; other site
1124991010760	Fimbrial protein; Region: Fimbrial; pfam00419
1124991010761	Fimbrial protein; Region: Fimbrial; cl01416
1124991010762	Fimbrial protein; Region: Fimbrial; pfam00419
1124991010763	Fimbrial protein; Region: Fimbrial; cl01416
1124991010764	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991010765	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991010766	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991010767	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991010768	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991010769	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991010770	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991010771	Fimbrial protein; Region: Fimbrial; cl01416
1124991010772	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991010773	active site
1124991010774	DNA binding site [nucleotide binding]
1124991010775	Int/Topo IB signature motif; other site
1124991010776	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1124991010777	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1124991010778	non-specific DNA binding site [nucleotide binding]; other site
1124991010779	salt bridge; other site
1124991010780	sequence-specific DNA binding site [nucleotide binding]; other site
1124991010781	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991010782	Fimbrial protein; Region: Fimbrial; cl01416
1124991010783	Fimbrial protein; Region: Fimbrial; pfam00419
1124991010784	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1124991010785	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991010786	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991010787	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1124991010788	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991010789	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991010790	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991010791	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991010792	Fimbrial protein; Region: Fimbrial; cl01416
1124991010793	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1124991010794	active site
1124991010795	DNA binding site [nucleotide binding]
1124991010796	Int/Topo IB signature motif; other site
1124991010797	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1124991010798	active site
1124991010799	tetramer interface [polypeptide binding]; other site
1124991010800	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1124991010801	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1124991010802	trimer interface [polypeptide binding]; other site
1124991010803	eyelet of channel; other site
1124991010804	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1124991010805	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1124991010806	active site
1124991010807	phosphorylation site [posttranslational modification]
1124991010808	intermolecular recognition site; other site
1124991010809	dimerization interface [polypeptide binding]; other site
1124991010810	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1124991010811	Walker A motif; other site
1124991010812	ATP binding site [chemical binding]; other site
1124991010813	Walker B motif; other site
1124991010814	arginine finger; other site
1124991010815	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1124991010816	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1124991010817	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1124991010818	dimerization interface [polypeptide binding]; other site
1124991010819	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1124991010820	dimer interface [polypeptide binding]; other site
1124991010821	phosphorylation site [posttranslational modification]
1124991010822	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1124991010823	ATP binding site [chemical binding]; other site
1124991010824	Mg2+ binding site [ion binding]; other site
1124991010825	G-X-G motif; other site
1124991010826	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1124991010827	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1124991010828	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1124991010829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991010830	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1124991010831	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1124991010832	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1124991010833	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1124991010834	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1124991010835	Domain of unknown function (DUF1992); Region: DUF1992; cl08096
1124991010836	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1124991010837	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1124991010838	putative chaperone protein EcpD; Provisional; Region: PRK09926
1124991010839	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1124991010840	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1124991010841	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1124991010842	PapC N-terminal domain; Region: PapC_N; pfam13954
1124991010843	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1124991010844	PapC C-terminal domain; Region: PapC_C; pfam13953
1124991010845	Fimbrial protein; Region: Fimbrial; pfam00419
1124991010846	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1124991010847	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1124991010848	SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829
1124991010849	active site
1124991010850	catalytic triad [active]
1124991010851	oxyanion hole [active]
1124991010852	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1124991010853	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
1124991010854	active site
1124991010855	oxyanion hole [active]
1124991010856	catalytic triad [active]
1124991010857	Transposase IS200 like; Region: Y1_Tnp; cl00848
1124991010858	histidyl-tRNA synthetase; Region: hisS; TIGR00442
1124991010859	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1124991010860	dimer interface [polypeptide binding]; other site
1124991010861	motif 1; other site
1124991010862	active site
1124991010863	motif 2; other site
1124991010864	motif 3; other site
1124991010865	histidine-histamine antiporter; Region: his_histam_anti; TIGR04298
1124991010866	histidine decarboxylase; Provisional; Region: PRK02769
1124991010867	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1124991010868	catalytic residue [active]
1124991010869	histidine-histamine antiporter; Region: his_histam_anti; TIGR04298
1124991010870	histidyl-tRNA synthetase; Region: hisS; TIGR00442
1124991010871	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1124991010872	dimer interface [polypeptide binding]; other site
1124991010873	motif 1; other site
1124991010874	active site
1124991010875	motif 2; other site
1124991010876	motif 3; other site
1124991010877	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
1124991010878	anticodon binding site; other site
1124991010879	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1124991010880	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1124991010881	DNA-binding site [nucleotide binding]; DNA binding site
1124991010882	UTRA domain; Region: UTRA; pfam07702