-- dump date 20140619_151101 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_879304.1 118466558 4529107 33..1529 1 NC_008595.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1529 dnaA 4529107 dnaA Mycobacterium avium 104 chromosomal replication initiation protein YP_879304.1 33 D 243243 CDS YP_879305.1 118465865 4527507 2150..3298 1 NC_008595.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3298 dnaN 4527507 dnaN Mycobacterium avium 104 DNA polymerase III subunit beta YP_879305.1 2150 D 243243 CDS YP_879306.1 118465169 4528659 3299..4456 1 NC_008595.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4456 recF 4528659 recF Mycobacterium avium 104 recombination protein F YP_879306.1 3299 D 243243 CDS YP_879307.1 118464189 4529300 4453..4998 1 NC_008595.1 identified by match to protein family HMM PF05258; hypothetical protein 4998 4529300 MAV_0004 Mycobacterium avium 104 hypothetical protein YP_879307.1 4453 D 243243 CDS YP_879308.1 118463778 4530129 5257..7290 1 NC_008595.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 7290 gyrB 4530129 gyrB Mycobacterium avium 104 DNA gyrase subunit B YP_879308.1 5257 D 243243 CDS YP_879309.1 118462773 4527270 7302..9821 1 NC_008595.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9821 gyrA 4527270 gyrA Mycobacterium avium 104 DNA gyrase subunit A YP_879309.1 7302 D 243243 CDS YP_879310.1 118462372 4529185 9924..10787 1 NC_008595.1 hypothetical protein 10787 4529185 MAV_0007 Mycobacterium avium 104 hypothetical protein YP_879310.1 9924 D 243243 CDS YP_879311.1 118466504 4525587 complement(11157..11735) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 11735 4525587 MAV_0009 Mycobacterium avium 104 TetR family transcriptional regulator YP_879311.1 11157 R 243243 CDS YP_879312.1 118465807 4525909 11932..13146 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 13146 4525909 MAV_0011 Mycobacterium avium 104 cytochrome P450 YP_879312.1 11932 D 243243 CDS YP_879313.1 118465230 4525601 complement(13148..13582) 1 NC_008595.1 hypothetical protein 13582 4525601 MAV_0012 Mycobacterium avium 104 hypothetical protein YP_879313.1 13148 R 243243 CDS YP_879314.1 118464521 4529441 13691..14221 1 NC_008595.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase B 14221 4529441 MAV_0013 Mycobacterium avium 104 peptidyl-prolyl cis-trans isomerase B YP_879314.1 13691 D 243243 CDS YP_879315.1 118465709 4530331 complement(14233..14514) 1 NC_008595.1 hypothetical protein 14514 4530331 MAV_0014 Mycobacterium avium 104 hypothetical protein YP_879315.1 14233 R 243243 CDS YP_879316.1 118464987 4527479 complement(14814..15095) 1 NC_008595.1 integral membrane protein involved in inhibition of the Z-ring formation; septation inhibitor protein 15095 4527479 MAV_0015 Mycobacterium avium 104 septation inhibitor protein YP_879316.1 14814 R 243243 CDS YP_879317.1 118462237 4526922 15226..15969 1 NC_008595.1 identified by match to protein family HMM PF05949; hypothetical protein 15969 4526922 MAV_0016 Mycobacterium avium 104 hypothetical protein YP_879317.1 15226 D 243243 CDS YP_879318.1 118464054 4529494 16018..16704 1 NC_008595.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 16704 4529494 MAV_0018 Mycobacterium avium 104 para-aminobenzoate synthase component II YP_879318.1 16018 D 243243 CDS YP_879319.1 118466937 4527772 complement(16682..18562) 1 NC_008595.1 identified by match to protein family HMM PF00069; match to protein family HMM PF03793; serine/threonine protein kinase 18562 4527772 MAV_0017 Mycobacterium avium 104 serine/threonine protein kinase YP_879319.1 16682 R 243243 CDS YP_879320.1 118462951 4526319 complement(18559..19824) 1 NC_008595.1 identified by match to protein family HMM PF00069; serine/threonine protein kinase 19824 4526319 MAV_0019 Mycobacterium avium 104 serine/threonine protein kinase YP_879320.1 18559 R 243243 CDS YP_879321.1 118465786 4526921 complement(19839..21317) 1 NC_008595.1 identified by match to protein family HMM PF00905; PbpA protein 21317 4526921 MAV_0020 Mycobacterium avium 104 PbpA protein YP_879321.1 19839 R 243243 CDS YP_879322.1 118465232 4525603 complement(21314..22723) 1 NC_008595.1 identified by match to protein family HMM PF01098; cell cycle protein, FtsW/RodA/SpoVE family protein 22723 4525603 MAV_0021 Mycobacterium avium 104 cell cycle protein, FtsW/RodA/SpoVE family protein YP_879322.1 21314 R 243243 CDS YP_879323.1 118466385 4526186 complement(22720..24219) 1 NC_008595.1 identified by match to protein family HMM PF00481; protein phosphatase 2C 24219 4526186 MAV_0022 Mycobacterium avium 104 protein phosphatase 2C YP_879323.1 22720 R 243243 CDS YP_879324.1 118466929 4527764 complement(24284..24682) 1 NC_008595.1 identified by match to protein family HMM PF00498; FHA domain-containing protein 24682 4527764 MAV_0023 Mycobacterium avium 104 FHA domain-containing protein YP_879324.1 24284 R 243243 CDS YP_879325.1 118465219 4529856 complement(24876..26513) 1 NC_008595.1 identified by match to protein family HMM PF00498; hypothetical protein 26513 4529856 MAV_0024 Mycobacterium avium 104 hypothetical protein YP_879325.1 24876 R 243243 CDS YP_879326.1 118465816 4525919 27020..27457 1 NC_008595.1 hypothetical protein 27457 4525919 MAV_0026 Mycobacterium avium 104 hypothetical protein YP_879326.1 27020 D 243243 CDS YP_879327.1 118464123 4526294 complement(27478..27849) 1 NC_008595.1 hypothetical protein 27849 4526294 MAV_0027 Mycobacterium avium 104 hypothetical protein YP_879327.1 27478 R 243243 CDS YP_879328.1 118463612 4527559 complement(27880..28383) 1 NC_008595.1 hypothetical protein 28383 4527559 MAV_0028 Mycobacterium avium 104 hypothetical protein YP_879328.1 27880 R 243243 CDS YP_879329.1 118464159 4526469 28598..28861 1 NC_008595.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 28861 4526469 MAV_0029 Mycobacterium avium 104 acyl carrier protein YP_879329.1 28598 D 243243 CDS YP_879330.1 118462530 4527673 28858..30414 1 NC_008595.1 converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; long-chain-fatty-acid--[acyl-carrier-protein] ligase 30414 4527673 MAV_0030 Mycobacterium avium 104 long-chain-fatty-acid--[acyl-carrier-protein] ligase YP_879330.1 28858 D 243243 CDS YP_879331.1 118463081 4527580 30569..32470 1 NC_008595.1 hypothetical protein 32470 4527580 MAV_0031 Mycobacterium avium 104 hypothetical protein YP_879331.1 30569 D 243243 CDS YP_879332.1 118466465 4528687 32692..32946 1 NC_008595.1 hypothetical protein 32946 4528687 MAV_0032 Mycobacterium avium 104 hypothetical protein YP_879332.1 32692 D 243243 CDS YP_879333.1 118466508 4525591 33419..34693 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 34693 4525591 MAV_0033 Mycobacterium avium 104 transposase, Mutator family protein YP_879333.1 33419 D 243243 CDS YP_879334.1 118463202 4527529 complement(34806..36131) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 36131 4527529 MAV_0034 Mycobacterium avium 104 transposase, Mutator family protein YP_879334.1 34806 R 243243 CDS YP_879335.1 118464090 4525851 complement(36248..37522) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 37522 4525851 MAV_0035 Mycobacterium avium 104 transposase, Mutator family protein YP_879335.1 36248 R 243243 CDS YP_879336.1 118464665 4528262 complement(37715..38959) 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 38959 4528262 MAV_0036 Mycobacterium avium 104 hypothetical protein YP_879336.1 37715 R 243243 CDS YP_879337.1 118465686 4525745 complement(39014..39343) 1 NC_008595.1 hypothetical protein 39343 4525745 MAV_0037 Mycobacterium avium 104 hypothetical protein YP_879337.1 39014 R 243243 CDS YP_879338.1 118466075 4527342 complement(39330..40322) 1 NC_008595.1 identified by match to protein family HMM PF02678; match to protein family HMM PF05726; hypothetical protein 40322 4527342 MAV_0038 Mycobacterium avium 104 hypothetical protein YP_879338.1 39330 R 243243 CDS YP_879339.1 118466848 4526957 complement(40327..41709) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 41709 4526957 MAV_0039 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879339.1 40327 R 243243 CDS YP_879340.1 118462762 4527852 complement(41803..42219) 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB family protein 42219 4527852 MAV_0040 Mycobacterium avium 104 transcription factor WhiB family protein YP_879340.1 41803 R 243243 CDS YP_879341.1 118463481 4525534 42362..43150 1 NC_008595.1 identified by match to protein family HMM PF01381; hypothetical protein 43150 4525534 MAV_0041 Mycobacterium avium 104 hypothetical protein YP_879341.1 42362 D 243243 CDS YP_879342.1 118463920 4528100 43147..43974 1 NC_008595.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 43974 4528100 MAV_0042 Mycobacterium avium 104 NLP/P60 family protein YP_879342.1 43147 D 243243 CDS YP_879343.1 118465006 4526272 44023..44385 1 NC_008595.1 hypothetical protein 44385 4526272 MAV_0043 Mycobacterium avium 104 hypothetical protein YP_879343.1 44023 D 243243 CDS YP_879344.1 118462713 4530087 44501..45952 1 NC_008595.1 hypothetical protein 45952 4530087 MAV_0044 Mycobacterium avium 104 hypothetical protein YP_879344.1 44501 D 243243 CDS YP_879345.1 118464594 4530105 46003..46320 1 NC_008595.1 hypothetical protein 46320 4530105 MAV_0045 Mycobacterium avium 104 hypothetical protein YP_879345.1 46003 D 243243 CDS YP_879346.1 118463831 4526049 46395..46628 1 NC_008595.1 hypothetical protein 46628 4526049 MAV_0046 Mycobacterium avium 104 hypothetical protein YP_879346.1 46395 D 243243 CDS YP_879347.1 118465580 4527127 complement(46662..46805) 1 NC_008595.1 hypothetical protein 46805 4527127 MAV_0047 Mycobacterium avium 104 hypothetical protein YP_879347.1 46662 R 243243 CDS YP_879348.1 118467122 4526149 46888..48576 1 NC_008595.1 hypothetical protein 48576 4526149 MAV_0048 Mycobacterium avium 104 hypothetical protein YP_879348.1 46888 D 243243 CDS YP_879349.1 118466858 4529810 48627..48950 1 NC_008595.1 hypothetical protein 48950 4529810 MAV_0049 Mycobacterium avium 104 hypothetical protein YP_879349.1 48627 D 243243 CDS YP_879350.1 118466337 4528768 complement(49093..49866) 1 NC_008595.1 identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03084; hypothetical protein 49866 4528768 MAV_0050 Mycobacterium avium 104 hypothetical protein YP_879350.1 49093 R 243243 CDS YP_879351.1 118464314 4526645 complement(49924..51210) 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 51210 4526645 MAV_0051 Mycobacterium avium 104 transporter, major facilitator family protein YP_879351.1 49924 R 243243 CDS YP_879352.1 118463947 4526599 51341..51946 1 NC_008595.1 identified by match to protein family HMM PF02622; hypothetical protein 51946 4526599 MAV_0052 Mycobacterium avium 104 hypothetical protein YP_879352.1 51341 D 243243 CDS YP_879353.1 118462500 4528578 complement(51962..52303) 1 NC_008595.1 hypothetical protein 52303 4528578 MAV_0053 Mycobacterium avium 104 hypothetical protein YP_879353.1 51962 R 243243 CDS YP_879354.1 118462540 4530541 complement(52359..53459) 1 NC_008595.1 proline-rich 28 kDa antigen 53459 4530541 MAV_0054 Mycobacterium avium 104 proline-rich 28 kDa antigen YP_879354.1 52359 R 243243 CDS YP_879355.1 118467113 4526376 53575..56553 1 NC_008595.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 56553 leuS 4526376 leuS Mycobacterium avium 104 leucyl-tRNA synthetase YP_879355.1 53575 D 243243 CDS YP_879356.1 118466568 4529117 complement(56560..57231) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 57231 4529117 MAV_0056 Mycobacterium avium 104 short chain dehydrogenase YP_879356.1 56560 R 243243 CDS YP_879357.1 118466014 4528459 complement(57290..57793) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 57793 4528459 MAV_0057 Mycobacterium avium 104 MarR family transcriptional regulator YP_879357.1 57290 R 243243 CDS YP_879358.1 118465112 4530464 complement(57860..58606) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 58606 4530464 MAV_0058 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_879358.1 57860 R 243243 CDS YP_879359.1 118464237 4528610 complement(58603..60399) 1 NC_008595.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 60399 4528610 MAV_0059 Mycobacterium avium 104 amino acid ABC transporter permease YP_879359.1 58603 R 243243 CDS YP_879360.1 118464635 4528970 complement(60462..61202) 1 NC_008595.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 61202 4528970 MAV_0060 Mycobacterium avium 104 GntR family transcriptional regulator YP_879360.1 60462 R 243243 CDS YP_879361.1 118463089 4528912 complement(61321..62100) 1 NC_008595.1 MmcI protein 62100 4528912 MAV_0061 Mycobacterium avium 104 MmcI protein YP_879361.1 61321 R 243243 CDS YP_879362.1 118463370 4528948 complement(62117..63031) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 63031 4528948 MAV_0062 Mycobacterium avium 104 alpha/beta hydrolase YP_879362.1 62117 R 243243 CDS YP_879363.1 118466485 4527615 complement(63055..64269) 1 NC_008595.1 hypothetical protein 64269 4527615 MAV_0063 Mycobacterium avium 104 hypothetical protein YP_879363.1 63055 R 243243 CDS YP_879364.1 118467333 4526971 complement(64266..65069) 1 NC_008595.1 identified by match to protein family HMM PF01261; AP endonuclease, family protein 2 65069 4526971 MAV_0064 Mycobacterium avium 104 AP endonuclease, family protein 2 YP_879364.1 64266 R 243243 CDS YP_879365.1 118465350 4526663 complement(65071..66240) 1 NC_008595.1 hypothetical protein 66240 4526663 MAV_0065 Mycobacterium avium 104 hypothetical protein YP_879365.1 65071 R 243243 CDS YP_879366.1 118463701 4530588 complement(66237..67364) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 67364 4530588 MAV_0066 Mycobacterium avium 104 hypothetical protein YP_879366.1 66237 R 243243 CDS YP_879367.1 118462233 4525570 complement(67496..68602) 1 NC_008595.1 identified by match to protein family HMM PF01658; match to protein family HMM PF07994; myo-inositol-1-phosphate synthase 68602 4525570 MAV_0067 Mycobacterium avium 104 myo-inositol-1-phosphate synthase YP_879367.1 67496 R 243243 CDS YP_879368.1 118462920 4526011 complement(68662..69204) 1 NC_008595.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 69204 4526011 MAV_0068 Mycobacterium avium 104 PadR family transcriptional regulator YP_879368.1 68662 R 243243 CDS YP_879369.1 118466212 4528891 complement(69351..70235) 1 NC_008595.1 identified by match to protein family HMM PF08044; hypothetical protein 70235 4528891 MAV_0069 Mycobacterium avium 104 hypothetical protein YP_879369.1 69351 R 243243 CDS YP_879370.1 118463492 4529071 70351..70794 1 NC_008595.1 hypothetical protein 70794 4529071 MAV_0070 Mycobacterium avium 104 hypothetical protein YP_879370.1 70351 D 243243 CDS YP_879371.1 118467310 4530302 70791..73424 1 NC_008595.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; transglycosylase 73424 4530302 MAV_0071 Mycobacterium avium 104 transglycosylase YP_879371.1 70791 D 243243 CDS YP_879372.1 118467279 4527081 73421..75058 1 NC_008595.1 hypothetical protein 75058 4527081 MAV_0072 Mycobacterium avium 104 hypothetical protein YP_879372.1 73421 D 243243 CDS YP_879373.1 118465152 4529242 75055..75696 1 NC_008595.1 identified by match to protein family HMM PF01965; DJ-1/PfpI family protein 75696 4529242 MAV_0073 Mycobacterium avium 104 DJ-1/PfpI family protein YP_879373.1 75055 D 243243 CDS YP_879374.1 118465214 4529851 75831..76121 1 NC_008595.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 76121 rpsF 4529851 rpsF Mycobacterium avium 104 30S ribosomal protein S6 YP_879374.1 75831 D 243243 CDS YP_879375.1 118466677 4526627 76788..77042 1 NC_008595.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 77042 rpsR 4526627 rpsR Mycobacterium avium 104 30S ribosomal protein S18 YP_879375.1 76788 D 243243 CDS YP_879376.1 118463189 4527712 77073..77531 1 NC_008595.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 77531 rplI 4527712 rplI Mycobacterium avium 104 50S ribosomal protein L9 YP_879376.1 77073 D 243243 CDS YP_879377.1 118465822 4525925 complement(77682..78008) 1 NC_008595.1 hypothetical protein 78008 4525925 MAV_0078 Mycobacterium avium 104 hypothetical protein YP_879377.1 77682 R 243243 CDS YP_879378.1 118463867 4527745 78063..80450 1 NC_008595.1 identified by match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR01443; replicative DNA helicase 80450 4527745 MAV_0079 Mycobacterium avium 104 replicative DNA helicase YP_879378.1 78063 D 243243 CDS YP_879379.1 118466020 4529906 complement(80591..81478) 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase domain-containing protein 81478 4529906 MAV_0080 Mycobacterium avium 104 acyltransferase domain-containing protein YP_879379.1 80591 R 243243 CDS YP_879380.1 118465316 4526570 complement(81564..82373) 1 NC_008595.1 hypothetical protein 82373 4526570 MAV_0081 Mycobacterium avium 104 hypothetical protein YP_879380.1 81564 R 243243 CDS YP_879381.1 118464894 4529623 82456..83025 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 83025 4529623 MAV_0082 Mycobacterium avium 104 TetR family transcriptional regulator YP_879381.1 82456 D 243243 CDS YP_879382.1 118465633 4528750 84930..87863 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; transport protein MmpL4 87863 4528750 MAV_0084 Mycobacterium avium 104 transport protein MmpL4 YP_879382.1 84930 D 243243 CDS YP_879383.1 118465091 4529981 88122..89186 1 NC_008595.1 hypothetical protein 89186 4529981 MAV_0085 Mycobacterium avium 104 hypothetical protein YP_879383.1 88122 D 243243 CDS YP_879384.1 118466758 4530753 89269..89544 1 NC_008595.1 hypothetical protein 89544 4530753 MAV_0086 Mycobacterium avium 104 hypothetical protein YP_879384.1 89269 D 243243 CDS YP_879385.1 118462980 4527408 89564..90304 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 90304 4527408 MAV_0087 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_879385.1 89564 D 243243 CDS YP_879386.1 118465215 4529852 complement(90333..90968) 1 NC_008595.1 hypothetical protein 90968 4529852 MAV_0088 Mycobacterium avium 104 hypothetical protein YP_879386.1 90333 R 243243 CDS YP_879387.1 118462287 4529292 91195..92631 1 NC_008595.1 identified by match to protein family HMM PF01565; FAD binding domain-containing protein 92631 4529292 MAV_0089 Mycobacterium avium 104 FAD binding domain-containing protein YP_879387.1 91195 D 243243 CDS YP_879388.1 118464391 4528280 92758..92877 1 NC_008595.1 hypothetical protein 92877 4528280 MAV_0090 Mycobacterium avium 104 hypothetical protein YP_879388.1 92758 D 243243 CDS YP_879389.1 118464475 4528849 93019..93696 1 NC_008595.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator protein 93696 4528849 MAV_0092 Mycobacterium avium 104 Crp/Fnr family transcriptional regulator protein YP_879389.1 93019 D 243243 CDS YP_879390.1 118465858 4530652 complement(93693..94136) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 94136 4530652 MAV_0091 Mycobacterium avium 104 glyoxalase YP_879390.1 93693 R 243243 CDS YP_879391.1 118467286 4527244 complement(94157..95089) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 95089 4527244 MAV_0093 Mycobacterium avium 104 alpha/beta hydrolase YP_879391.1 94157 R 243243 CDS YP_879392.1 118466614 4526851 complement(95180..96031) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 96031 4526851 MAV_0094 Mycobacterium avium 104 LysR family transcriptional regulator YP_879392.1 95180 R 243243 CDS YP_879393.1 118465826 4525498 96201..97118 1 NC_008595.1 identified by match to protein family HMM PF00892; hypothetical protein 97118 4525498 MAV_0095 Mycobacterium avium 104 hypothetical protein YP_879393.1 96201 D 243243 CDS YP_879394.1 118464213 4526893 97888..98454 1 NC_008595.1 identified by match to protein family HMM PF00583; phosphinothricin N-acetyltransferase 98454 4526893 MAV_0097 Mycobacterium avium 104 phosphinothricin N-acetyltransferase YP_879394.1 97888 D 243243 CDS YP_879395.1 118462494 4530690 complement(98467..99156) 1 NC_008595.1 hypothetical protein 99156 4530690 MAV_0098 Mycobacterium avium 104 hypothetical protein YP_879395.1 98467 R 243243 CDS YP_879396.1 118462380 4529193 complement(99147..99749) 1 NC_008595.1 hypothetical protein 99749 4529193 MAV_0099 Mycobacterium avium 104 hypothetical protein YP_879396.1 99147 R 243243 CDS YP_879397.1 118467326 4526964 100937..101794 1 NC_008595.1 identified by match to protein family HMM PF02405; ABC transporter transmembrane protein 101794 4526964 MAV_0101 Mycobacterium avium 104 ABC transporter transmembrane protein YP_879397.1 100937 D 243243 CDS YP_879398.1 118465369 4529230 101795..103351 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 103351 4529230 MAV_0102 Mycobacterium avium 104 mce related protein YP_879398.1 101795 D 243243 CDS YP_879399.1 118463822 4526078 103354..104427 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 104427 4526078 MAV_0103 Mycobacterium avium 104 virulence factor Mce YP_879399.1 103354 D 243243 CDS YP_879400.1 118464334 4529839 104420..105466 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 105466 4529839 MAV_0104 Mycobacterium avium 104 virulence factor Mce YP_879400.1 104420 D 243243 CDS YP_879401.1 118462753 4527843 105463..106578 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 106578 4527843 MAV_0105 Mycobacterium avium 104 virulence factor Mce YP_879401.1 105463 D 243243 CDS YP_879402.1 118464466 4527059 106581..107813 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 107813 4527059 MAV_0106 Mycobacterium avium 104 mce related protein YP_879402.1 106581 D 243243 CDS YP_879403.1 118463870 4527748 107810..109060 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 109060 4527748 MAV_0107 Mycobacterium avium 104 mce related protein YP_879403.1 107810 D 243243 CDS YP_879404.1 118464842 4527958 109092..109688 1 NC_008595.1 hypothetical protein 109688 4527958 MAV_0108 Mycobacterium avium 104 hypothetical protein YP_879404.1 109092 D 243243 CDS YP_879405.1 118462906 4528169 109702..110487 1 NC_008595.1 hypothetical protein 110487 4528169 MAV_0109 Mycobacterium avium 104 hypothetical protein YP_879405.1 109702 D 243243 CDS YP_879406.1 118464655 4528252 110650..111882 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 111882 4528252 MAV_0110 Mycobacterium avium 104 TetR family transcriptional regulator YP_879406.1 110650 D 243243 CDS YP_879407.1 118464080 4528393 112090..112314 1 NC_008595.1 hypothetical protein 112314 4528393 MAV_0111 Mycobacterium avium 104 hypothetical protein YP_879407.1 112090 D 243243 CDS YP_879408.1 118466320 4528362 112326..112670 1 NC_008595.1 hypothetical protein 112670 4528362 MAV_0112 Mycobacterium avium 104 hypothetical protein YP_879408.1 112326 D 243243 CDS YP_879409.1 118465872 4527514 complement(112726..112893) 1 NC_008595.1 hypothetical protein 112893 4527514 MAV_0113 Mycobacterium avium 104 hypothetical protein YP_879409.1 112726 R 243243 CDS YP_879410.1 118462222 4525559 complement(113006..113794) 1 NC_008595.1 hypothetical protein 113794 4525559 MAV_0114 Mycobacterium avium 104 hypothetical protein YP_879410.1 113006 R 243243 CDS YP_879411.1 118465898 4527932 complement(113791..114186) 1 NC_008595.1 hypothetical protein 114186 4527932 MAV_0115 Mycobacterium avium 104 hypothetical protein YP_879411.1 113791 R 243243 CDS YP_879412.1 118463621 4527325 114285..114845 1 NC_008595.1 hypothetical protein 114845 4527325 MAV_0116 Mycobacterium avium 104 hypothetical protein YP_879412.1 114285 D 243243 CDS YP_879413.1 118464188 4529299 114858..115163 1 NC_008595.1 identified by match to protein family HMM PF00934; PE family protein 115163 4529299 MAV_0117 Mycobacterium avium 104 PE family protein YP_879413.1 114858 D 243243 CDS YP_879414.1 118465587 4527134 115166..116839 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 116839 4527134 MAV_0118 Mycobacterium avium 104 PPE family protein YP_879414.1 115166 D 243243 CDS YP_879415.1 118465195 4530392 complement(116861..117556) 1 NC_008595.1 identified by match to protein family HMM PF05724; thiopurine S-methyltransferase (tpmt) superfamily protein 117556 4530392 MAV_0119 Mycobacterium avium 104 thiopurine S-methyltransferase (tpmt) superfamily protein YP_879415.1 116861 R 243243 CDS YP_879416.1 118464176 4526486 117698..118120 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 118120 4526486 MAV_0120 Mycobacterium avium 104 hypothetical protein YP_879416.1 117698 D 243243 CDS YP_879417.1 118463772 4530123 118377..119885 1 NC_008595.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; carbonate dehydratase 119885 4530123 MAV_0121 Mycobacterium avium 104 carbonate dehydratase YP_879417.1 118377 D 243243 CDS YP_879418.1 118462735 4527806 complement(119919..120776) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 120776 4527806 MAV_0122 Mycobacterium avium 104 hypothetical protein YP_879418.1 119919 R 243243 CDS YP_879419.1 118462333 4525678 120847..121824 1 NC_008595.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 121824 4525678 MAV_0123 Mycobacterium avium 104 D-isomer specific 2-hydroxyacid dehydrogenase YP_879419.1 120847 D 243243 CDS YP_879420.1 118466457 4528678 121922..122347 1 NC_008595.1 hypothetical protein 122347 4528678 MAV_0124 Mycobacterium avium 104 hypothetical protein YP_879420.1 121922 D 243243 CDS YP_879421.1 118464353 4529155 complement(122354..122461) 1 NC_008595.1 hypothetical protein 122461 4529155 MAV_0125 Mycobacterium avium 104 hypothetical protein YP_879421.1 122354 R 243243 CDS YP_879422.1 118462304 4525649 complement(122484..123839) 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; bifunctional wax ester synthase/acyl-CoA diacylglycerol acyltransferase 123839 4525649 MAV_0126 Mycobacterium avium 104 bifunctional wax ester synthase/acyl-CoA diacylglycerol acyltransferase YP_879422.1 122484 R 243243 CDS YP_879423.1 118462780 4527277 complement(123960..124226) 1 NC_008595.1 PhoY2 protein 124226 4527277 MAV_0127 Mycobacterium avium 104 PhoY2 protein YP_879423.1 123960 R 243243 CDS YP_879424.1 118467180 4530150 complement(126283..126858) 1 NC_008595.1 hypothetical protein 126858 4530150 MAV_0129 Mycobacterium avium 104 hypothetical protein YP_879424.1 126283 R 243243 CDS YP_879425.1 118465186 4530383 127072..127956 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1 127956 4530383 MAV_0130 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase 1 YP_879425.1 127072 D 243243 CDS YP_879426.1 118462564 4528623 complement(127981..128124) 1 NC_008595.1 hypothetical protein 128124 4528623 MAV_0131 Mycobacterium avium 104 hypothetical protein YP_879426.1 127981 R 243243 CDS YP_879427.1 118465754 4530446 128159..128512 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 128512 4530446 MAV_0132 Mycobacterium avium 104 glyoxalase YP_879427.1 128159 D 243243 CDS YP_879428.1 118466997 4529525 complement(128545..128811) 1 NC_008595.1 hypothetical protein 128811 4529525 MAV_0133 Mycobacterium avium 104 hypothetical protein YP_879428.1 128545 R 243243 CDS YP_879429.1 118462954 4526322 complement(128808..129701) 1 NC_008595.1 hypothetical protein 129701 4526322 MAV_0134 Mycobacterium avium 104 hypothetical protein YP_879429.1 128808 R 243243 CDS YP_879430.1 118463512 4527692 complement(129710..130324) 1 NC_008595.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 130324 4527692 MAV_0135 Mycobacterium avium 104 PadR family transcriptional regulator YP_879430.1 129710 R 243243 CDS YP_879431.1 118466624 4526862 130383..130868 1 NC_008595.1 hypothetical protein 130868 4526862 MAV_0136 Mycobacterium avium 104 hypothetical protein YP_879431.1 130383 D 243243 CDS YP_879432.1 118462392 4525935 130874..131917 1 NC_008595.1 identified by match to protein family HMM PF00296; oxidoreductase 131917 4525935 MAV_0137 Mycobacterium avium 104 oxidoreductase YP_879432.1 130874 D 243243 CDS YP_879433.1 118465645 4526170 complement(131951..133168) 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 133168 4526170 MAV_0138 Mycobacterium avium 104 transporter, major facilitator family protein YP_879433.1 131951 R 243243 CDS YP_879434.1 118467046 4526502 133335..133616 1 NC_008595.1 hypothetical protein 133616 4526502 MAV_0139 Mycobacterium avium 104 hypothetical protein YP_879434.1 133335 D 243243 CDS YP_879435.1 118464510 4525553 133761..134489 1 NC_008595.1 identified by match to protein family HMM PF00005; nitrate/sulfonate/bicarbonate ABC transporter ATPase 134489 4525553 MAV_0140 Mycobacterium avium 104 nitrate/sulfonate/bicarbonate ABC transporter ATPase YP_879435.1 133761 D 243243 CDS YP_879436.1 118465370 4529231 134486..135451 1 NC_008595.1 identified by match to protein family HMM TIGR01728; sulfonate binding protein 135451 4529231 MAV_0141 Mycobacterium avium 104 sulfonate binding protein YP_879436.1 134486 D 243243 CDS YP_879437.1 118463383 4528961 135514..136215 1 NC_008595.1 identified by match to protein family HMM PF00528; aliphatic sulfonates ABC transporter permease 136215 4528961 MAV_0143 Mycobacterium avium 104 aliphatic sulfonates ABC transporter permease YP_879437.1 135514 D 243243 CDS YP_879438.1 118463657 4525949 complement(136212..137165) 1 NC_008595.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase 137165 4525949 MAV_0142 Mycobacterium avium 104 FAD dependent oxidoreductase YP_879438.1 136212 R 243243 CDS YP_879439.1 118466188 4530178 complement(137165..138382) 1 NC_008595.1 identified by match to protein family HMM PF00583; hypothetical protein 138382 4530178 MAV_0144 Mycobacterium avium 104 hypothetical protein YP_879439.1 137165 R 243243 CDS YP_879440.1 118465842 4525514 complement(138439..139650) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 139650 4525514 MAV_0145 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879440.1 138439 R 243243 CDS YP_879441.1 118464449 4525980 complement(139647..140294) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 140294 4525980 MAV_0146 Mycobacterium avium 104 TetR family transcriptional regulator YP_879441.1 139647 R 243243 CDS YP_879442.1 118462291 4525636 140441..141769 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 141769 4525636 MAV_0147 Mycobacterium avium 104 sensor histidine kinase YP_879442.1 140441 D 243243 CDS YP_879443.1 118462984 4527412 141877..142659 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 142659 4527412 MAV_0148 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_879443.1 141877 D 243243 CDS YP_879444.1 118463534 4526840 142659..143237 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 143237 4526840 MAV_0149 Mycobacterium avium 104 TetR family transcriptional regulator YP_879444.1 142659 D 243243 CDS YP_879445.1 118464402 4530796 143254..143652 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 143652 4530796 MAV_0150 Mycobacterium avium 104 glyoxalase YP_879445.1 143254 D 243243 CDS YP_879446.1 118462731 4527802 143926..144237 1 NC_008595.1 PE family protein 144237 4527802 MAV_0151 Mycobacterium avium 104 PE family protein YP_879446.1 143926 D 243243 CDS YP_879447.1 118466409 4526252 145552..145866 1 NC_008595.1 hypothetical protein 145866 4526252 MAV_0153 Mycobacterium avium 104 hypothetical protein YP_879447.1 145552 D 243243 CDS YP_879448.1 118467234 4529791 145913..146200 1 NC_008595.1 hypothetical protein 146200 4529791 MAV_0154 Mycobacterium avium 104 hypothetical protein YP_879448.1 145913 D 243243 CDS YP_879449.1 118466894 4528408 146305..147135 1 NC_008595.1 hypothetical protein 147135 4528408 MAV_0155 Mycobacterium avium 104 hypothetical protein YP_879449.1 146305 D 243243 CDS YP_879450.1 118465993 4526135 147365..148288 1 NC_008595.1 hypothetical protein 148288 4526135 MAV_0156 Mycobacterium avium 104 hypothetical protein YP_879450.1 147365 D 243243 CDS YP_879451.1 118464269 4528224 148384..149814 1 NC_008595.1 identified by match to protein family HMM PF04600; match to protein family HMM TIGR02958; secretion protein Snm4 149814 snm 4528224 snm Mycobacterium avium 104 secretion protein Snm4 YP_879451.1 148384 D 243243 CDS YP_879452.1 118462273 4529278 149799..151457 1 NC_008595.1 identified by match to protein family HMM PF00082; subtilase 151457 4529278 MAV_0158 Mycobacterium avium 104 subtilase YP_879452.1 149799 D 243243 CDS YP_879453.1 118463849 4529948 151454..153040 1 NC_008595.1 hypothetical protein 153040 4529948 MAV_0159 Mycobacterium avium 104 hypothetical protein YP_879453.1 151454 D 243243 CDS YP_879454.1 118465735 4525698 153067..154908 1 NC_008595.1 identified by match to protein family HMM PF00004; ATPase AAA 154908 4525698 MAV_0160 Mycobacterium avium 104 ATPase AAA YP_879454.1 153067 D 243243 CDS YP_879455.1 118465036 4525815 complement(154922..155362) 1 NC_008595.1 identified by match to protein family HMM TIGR00026; hypothetical protein 155362 4525815 MAV_0161 Mycobacterium avium 104 hypothetical protein YP_879455.1 154922 R 243243 CDS YP_879456.1 118466077 4527344 complement(155364..156224) 1 NC_008595.1 identified by match to protein family HMM PF05368; hypothetical protein 156224 4527344 MAV_0162 Mycobacterium avium 104 hypothetical protein YP_879456.1 155364 R 243243 CDS YP_879457.1 118463107 4527169 156337..157194 1 NC_008595.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigI 157194 sigI 4527169 sigI Mycobacterium avium 104 RNA polymerase sigma factor SigI YP_879457.1 156337 D 243243 CDS YP_879458.1 118462837 4528652 complement(157191..158342) 1 NC_008595.1 hypothetical protein 158342 4528652 MAV_0163 Mycobacterium avium 104 hypothetical protein YP_879458.1 157191 R 243243 CDS YP_879459.1 118465497 4526793 complement(158806..158961) 1 NC_008595.1 hypothetical protein 158961 4526793 MAV_0165 Mycobacterium avium 104 hypothetical protein YP_879459.1 158806 R 243243 CDS YP_879460.1 118462724 4530098 158956..163545 1 NC_008595.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898; ferredoxin-dependent glutamate synthase 1 163545 4530098 MAV_0166 Mycobacterium avium 104 ferredoxin-dependent glutamate synthase 1 YP_879460.1 158956 D 243243 CDS YP_879461.1 118464585 4530289 163538..165013 1 NC_008595.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 165013 gltD 4530289 gltD Mycobacterium avium 104 glutamate synthase subunit beta YP_879461.1 163538 D 243243 CDS YP_879462.1 118463881 4530558 165167..165307 1 NC_008595.1 hypothetical protein 165307 4530558 MAV_0168 Mycobacterium avium 104 hypothetical protein YP_879462.1 165167 D 243243 CDS YP_879463.1 118465718 4527453 complement(165375..166226) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 166226 4527453 MAV_0169 Mycobacterium avium 104 hypothetical protein YP_879463.1 165375 R 243243 CDS YP_879464.1 118464986 4527478 166278..166718 1 NC_008595.1 hypothetical protein 166718 4527478 MAV_0170 Mycobacterium avium 104 hypothetical protein YP_879464.1 166278 D 243243 CDS YP_879465.1 118466787 4529345 166797..167801 1 NC_008595.1 identified by match to protein family HMM PF02811; hypothetical protein 167801 4529345 MAV_0171 Mycobacterium avium 104 hypothetical protein YP_879465.1 166797 D 243243 CDS YP_879466.1 118463437 4528317 complement(167808..169010) 1 NC_008595.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 169010 4528317 MAV_0172 Mycobacterium avium 104 DNA polymerase IV YP_879466.1 167808 R 243243 CDS YP_879467.1 118462741 4527812 complement(169040..169681) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 169681 4527812 MAV_0173 Mycobacterium avium 104 TetR family transcriptional regulator YP_879467.1 169040 R 243243 CDS YP_879468.1 118463805 4525887 169807..171228 1 NC_008595.1 monooxygenase, flavin-binding family protein 171228 4525887 MAV_0175 Mycobacterium avium 104 monooxygenase, flavin-binding family protein YP_879468.1 169807 D 243243 CDS YP_879469.1 118463623 4527327 complement(171225..171710) 1 NC_008595.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 171710 4527327 MAV_0174 Mycobacterium avium 104 ribonuclease activity regulator protein RraA YP_879469.1 171225 R 243243 CDS YP_879470.1 118465552 4525800 complement(171719..172129) 1 NC_008595.1 hypothetical protein 172129 4525800 MAV_0176 Mycobacterium avium 104 hypothetical protein YP_879470.1 171719 R 243243 CDS YP_879471.1 118465059 4527035 complement(172226..172732) 1 NC_008595.1 identified by match to protein family HMM PF04234; copper resistance protein CopC 172732 4527035 MAV_0177 Mycobacterium avium 104 copper resistance protein CopC YP_879471.1 172226 R 243243 CDS YP_879472.1 118466866 4529818 complement(172729..173361) 1 NC_008595.1 identified by match to protein family HMM PF07987; nuclear export factor GLE1 family protein 173361 4529818 MAV_0178 Mycobacterium avium 104 nuclear export factor GLE1 family protein YP_879472.1 172729 R 243243 CDS YP_879473.1 118467133 4527146 complement(173367..174023) 1 NC_008595.1 hypothetical protein 174023 4527146 MAV_0179 Mycobacterium avium 104 hypothetical protein YP_879473.1 173367 R 243243 CDS YP_879474.1 118463431 4528310 complement(174170..174568) 1 NC_008595.1 hypothetical protein 174568 4528310 MAV_0180 Mycobacterium avium 104 hypothetical protein YP_879474.1 174170 R 243243 CDS YP_879475.1 118462757 4527847 complement(174992..175456) 1 NC_008595.1 hypothetical protein 175456 4527847 MAV_0181 Mycobacterium avium 104 hypothetical protein YP_879475.1 174992 R 243243 CDS YP_879476.1 118464258 4527443 complement(175683..176306) 1 NC_008595.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; [Mn]-superoxide dismutase 176306 4527443 MAV_0182 Mycobacterium avium 104 [Mn]-superoxide dismutase YP_879476.1 175683 R 243243 CDS YP_879477.1 118463574 4530729 complement(176467..176622) 1 NC_008595.1 hypothetical protein 176622 4530729 MAV_0183 Mycobacterium avium 104 hypothetical protein YP_879477.1 176467 R 243243 CDS YP_879478.1 118466756 4526357 177234..178055 1 NC_008595.1 hypothetical protein 178055 4526357 MAV_0184 Mycobacterium avium 104 hypothetical protein YP_879478.1 177234 D 243243 CDS YP_879479.1 118463842 4529941 178060..178878 1 NC_008595.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 178878 4529941 MAV_0186 Mycobacterium avium 104 glycerophosphoryl diester phosphodiesterase YP_879479.1 178060 D 243243 CDS YP_879480.1 118463120 4527182 complement(178875..179828) 1 NC_008595.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator 179828 4527182 MAV_0185 Mycobacterium avium 104 transcriptional regulator YP_879480.1 178875 R 243243 CDS YP_879481.1 118463004 4530634 complement(180134..180928) 1 NC_008595.1 hypothetical protein 180928 4530634 MAV_0187 Mycobacterium avium 104 hypothetical protein YP_879481.1 180134 R 243243 CDS YP_879482.1 118462360 4527988 181019..181966 1 NC_008595.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 181966 4527988 MAV_0188 Mycobacterium avium 104 prephenate dehydratase YP_879482.1 181019 D 243243 CDS YP_879483.1 118464437 4525968 181963..182658 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 182658 4525968 MAV_0189 Mycobacterium avium 104 phosphoglycerate mutase YP_879483.1 181963 D 243243 CDS YP_879484.1 118463694 4530581 complement(182668..182826) 1 NC_008595.1 hypothetical protein 182826 4530581 MAV_0190 Mycobacterium avium 104 hypothetical protein YP_879484.1 182668 R 243243 CDS YP_879485.1 118465828 4525500 complement(182914..183258) 1 NC_008595.1 identified by match to protein family HMM PF06262; hypothetical protein 183258 4525500 MAV_0191 Mycobacterium avium 104 hypothetical protein YP_879485.1 182914 R 243243 CDS YP_879486.1 118465173 4528663 complement(183270..184616) 1 NC_008595.1 hypothetical protein 184616 4528663 MAV_0192 Mycobacterium avium 104 hypothetical protein YP_879486.1 183270 R 243243 CDS YP_879487.1 118467339 4526977 184726..186003 1 NC_008595.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 186003 serS 4526977 serS Mycobacterium avium 104 seryl-tRNA synthetase YP_879487.1 184726 D 243243 CDS YP_879488.1 118466816 4527381 complement(186000..186749) 1 NC_008595.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 186749 4527381 MAV_0193 Mycobacterium avium 104 AraC family transcriptional regulator YP_879488.1 186000 R 243243 CDS YP_879489.1 118463325 4529565 186819..187400 1 NC_008595.1 hypothetical protein 187400 4529565 MAV_0196 Mycobacterium avium 104 hypothetical protein YP_879489.1 186819 D 243243 CDS YP_879490.1 118463108 4527170 complement(187397..187882) 1 NC_008595.1 hypothetical protein 187882 4527170 MAV_0195 Mycobacterium avium 104 hypothetical protein YP_879490.1 187397 R 243243 CDS YP_879491.1 118463146 4527784 187952..188590 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 188590 4527784 MAV_0197 Mycobacterium avium 104 TetR family transcriptional regulator YP_879491.1 187952 D 243243 CDS YP_879492.1 118466118 4529751 188639..190213 1 NC_008595.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase, putative 190213 4529751 MAV_0198 Mycobacterium avium 104 FAD dependent oxidoreductase, putative YP_879492.1 188639 D 243243 CDS YP_879493.1 118462553 4530554 complement(190215..190550) 1 NC_008595.1 hypothetical protein 190550 4530554 MAV_0199 Mycobacterium avium 104 hypothetical protein YP_879493.1 190215 R 243243 CDS YP_879494.1 118464045 4529017 complement(190547..192085) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske 2Fe-2S family protein 192085 4529017 MAV_0200 Mycobacterium avium 104 Rieske 2Fe-2S family protein YP_879494.1 190547 R 243243 CDS YP_879495.1 118464781 4529136 complement(192146..192289) 1 NC_008595.1 hypothetical protein 192289 4529136 MAV_0201 Mycobacterium avium 104 hypothetical protein YP_879495.1 192146 R 243243 CDS YP_879496.1 118464870 4530706 192316..193083 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase 193083 4530706 MAV_0202 Mycobacterium avium 104 acyltransferase YP_879496.1 192316 D 243243 CDS YP_879497.1 118465016 4530065 193090..193869 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase 193869 4530065 MAV_0203 Mycobacterium avium 104 acyltransferase YP_879497.1 193090 D 243243 CDS YP_879498.1 118467149 4527163 193883..194668 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase 194668 4527163 MAV_0204 Mycobacterium avium 104 acyltransferase YP_879498.1 193883 D 243243 CDS YP_879499.1 118463875 4527753 194697..195512 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 195512 4527753 MAV_0205 Mycobacterium avium 104 hypothetical protein YP_879499.1 194697 D 243243 CDS YP_879500.1 118465940 4527936 complement(195539..197167) 1 NC_008595.1 identified by match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 197167 4527936 MAV_0206 Mycobacterium avium 104 N-acetylmuramoyl-L-alanine amidase YP_879500.1 195539 R 243243 CDS YP_879501.1 118462703 4526683 complement(197302..198348) 1 NC_008595.1 Erp protein 198348 4526683 MAV_0207 Mycobacterium avium 104 Erp protein YP_879501.1 197302 R 243243 CDS YP_879502.1 118462865 4527092 198603..199811 1 NC_008595.1 identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031; UDP-galactopyranose mutase 199811 glf 4527092 glf Mycobacterium avium 104 UDP-galactopyranose mutase YP_879502.1 198603 D 243243 CDS YP_879503.1 118462480 4530676 199871..201748 1 NC_008595.1 bifunctional udp-galactofuranosyl transferase glft 201748 4530676 MAV_0209 Mycobacterium avium 104 bifunctional udp-galactofuranosyl transferase glft YP_879503.1 199871 D 243243 CDS YP_879504.1 118467150 4527164 201828..202280 1 NC_008595.1 identified by match to protein family HMM PF01569; PAP2 superfamily protein 202280 4527164 MAV_0210 Mycobacterium avium 104 PAP2 superfamily protein YP_879504.1 201828 D 243243 CDS YP_879505.1 118466206 4530196 202277..203194 1 NC_008595.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 203194 4530196 MAV_0211 Mycobacterium avium 104 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_879505.1 202277 D 243243 CDS YP_879506.1 118465744 4525707 203181..205163 1 NC_008595.1 hypothetical protein 205163 4525707 MAV_0212 Mycobacterium avium 104 hypothetical protein YP_879506.1 203181 D 243243 CDS YP_879507.1 118464727 4529414 205160..205318 1 NC_008595.1 hypothetical protein 205318 4529414 MAV_0213 Mycobacterium avium 104 hypothetical protein YP_879507.1 205160 D 243243 CDS YP_879508.1 118467129 4526156 205514..206557 1 NC_008595.1 identified by match to protein family HMM PF00756; antigen 85-A 206557 4526156 MAV_0214 Mycobacterium avium 104 antigen 85-A YP_879508.1 205514 D 243243 CDS YP_879509.1 118462597 4528501 206704..207621 1 NC_008595.1 identified by match to protein family HMM PF00756; antigen 85-C 207621 4528501 MAV_0215 Mycobacterium avium 104 antigen 85-C YP_879509.1 206704 D 243243 CDS YP_879510.1 118463426 4528305 207786..208796 1 NC_008595.1 identified by match to protein family HMM PF01083; cutinase 208796 4528305 MAV_0216 Mycobacterium avium 104 cutinase YP_879510.1 207786 D 243243 CDS YP_879511.1 118464005 4529267 209078..210976 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 210976 4529267 MAV_0217 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_879511.1 209078 D 243243 CDS YP_879512.1 118464899 4530734 210988..216363 1 NC_008595.1 identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801; polyketide synthase 216363 4530734 MAV_0218 Mycobacterium avium 104 polyketide synthase YP_879512.1 210988 D 243243 CDS YP_879513.1 118465452 4526220 216363..217937 1 NC_008595.1 identified by match to protein family HMM PF01039; propionyl-CoA carboxylase beta chain 217937 4526220 MAV_0220 Mycobacterium avium 104 propionyl-CoA carboxylase beta chain YP_879513.1 216363 D 243243 CDS YP_879514.1 118464905 4530740 complement(217934..218773) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 218773 4530740 MAV_0219 Mycobacterium avium 104 methyltransferase, putative, family protein YP_879514.1 217934 R 243243 CDS YP_879515.1 118463095 4528918 complement(218828..219634) 1 NC_008595.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 219634 4528918 MAV_0221 Mycobacterium avium 104 AraC family transcriptional regulator YP_879515.1 218828 R 243243 CDS YP_879516.1 118463683 4528530 complement(219658..221427) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 221427 4528530 MAV_0222 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879516.1 219658 R 243243 CDS YP_879517.1 118464307 4526637 complement(221438..221953) 1 NC_008595.1 hypothetical protein 221953 4526637 MAV_0223 Mycobacterium avium 104 hypothetical protein YP_879517.1 221438 R 243243 CDS YP_879518.1 118466298 4529545 complement(225293..228574) 1 NC_008595.1 arabinosyltransferase C 228574 4529545 MAV_0225 Mycobacterium avium 104 arabinosyltransferase C YP_879518.1 225293 R 243243 CDS YP_879519.1 118467005 4529475 228797..229951 1 NC_008595.1 identified by match to protein family HMM PF00486; match to protein family HMM PF00498; match to protein family HMM PF03704; EmbR protein 229951 4529475 MAV_0226 Mycobacterium avium 104 EmbR protein YP_879519.1 228797 D 243243 CDS YP_879520.1 118463200 4527527 complement(229955..230578) 1 NC_008595.1 identified by match to protein family HMM TIGR03083; hypothetical protein 230578 4527527 MAV_0227 Mycobacterium avium 104 hypothetical protein YP_879520.1 229955 R 243243 CDS YP_879521.1 118462548 4530549 230761..230973 1 NC_008595.1 hypothetical protein 230973 4530549 MAV_0228 Mycobacterium avium 104 hypothetical protein YP_879521.1 230761 D 243243 CDS YP_879522.1 118463312 4529552 complement(231032..234190) 1 NC_008595.1 identified by match to protein family HMM PF04602; arabinosyltransferase A 234190 4529552 MAV_0229 Mycobacterium avium 104 arabinosyltransferase A YP_879522.1 231032 R 243243 CDS YP_879523.1 118464062 4529502 complement(234314..236362) 1 NC_008595.1 hypothetical protein 236362 4529502 MAV_0230 Mycobacterium avium 104 hypothetical protein YP_879523.1 234314 R 243243 CDS YP_879524.1 118464774 4529129 complement(236365..237129) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 237129 4529129 MAV_0231 Mycobacterium avium 104 short chain dehydrogenase YP_879524.1 236365 R 243243 CDS YP_879525.1 118465450 4527319 complement(237130..238530) 1 NC_008595.1 identified by match to protein family HMM PF01565; oxidoreductase, FAD-binding 238530 4527319 MAV_0232 Mycobacterium avium 104 oxidoreductase, FAD-binding YP_879525.1 237130 R 243243 CDS YP_879526.1 118466057 4530027 complement(238563..238967) 1 NC_008595.1 identified by match to protein family HMM PF04138; membrane protein 238967 4530027 MAV_0233 Mycobacterium avium 104 membrane protein YP_879526.1 238563 R 243243 CDS YP_879527.1 118466969 4530368 complement(238978..239454) 1 NC_008595.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 239454 4530368 MAV_0234 Mycobacterium avium 104 nucleoside diphosphate kinase regulator YP_879527.1 238978 R 243243 CDS YP_879528.1 118466189 4530179 complement(239896..240783) 1 NC_008595.1 identified by match to protein family HMM PF02668; taurine catabolism dioxygenase TauD/TfdA 240783 4530179 MAV_0235 Mycobacterium avium 104 taurine catabolism dioxygenase TauD/TfdA YP_879528.1 239896 R 243243 CDS YP_879529.1 118466977 4530376 complement(240808..241638) 1 NC_008595.1 identified by match to protein family HMM PF01061; O-antigen ABC transporter permease 241638 4530376 MAV_0236 Mycobacterium avium 104 O-antigen ABC transporter permease YP_879529.1 240808 R 243243 CDS YP_879530.1 118466257 4526876 complement(241635..242549) 1 NC_008595.1 identified by match to protein family HMM PF00535; glycosyl transferase 242549 4526876 MAV_0237 Mycobacterium avium 104 glycosyl transferase YP_879530.1 241635 R 243243 CDS YP_879531.1 118463293 4525987 complement(242546..243307) 1 NC_008595.1 identified by match to protein family HMM PF00005; O-antigen export system ATP-binding protein RfbB 243307 4525987 MAV_0238 Mycobacterium avium 104 O-antigen export system ATP-binding protein RfbB YP_879531.1 242546 R 243243 CDS YP_879532.1 118462610 4528514 complement(243368..243877) 1 NC_008595.1 hypothetical protein 243877 4528514 MAV_0239 Mycobacterium avium 104 hypothetical protein YP_879532.1 243368 R 243243 CDS YP_879533.1 118466029 4529915 245990..247186 1 NC_008595.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01976; cysteine desulfurase 247186 4529915 MAV_0241 Mycobacterium avium 104 cysteine desulfurase YP_879533.1 245990 D 243243 CDS YP_879534.1 118465136 4529167 complement(247191..248171) 1 NC_008595.1 identified by match to protein family HMM PF00107; match to protein family HMM TIGR02824; quinone oxidoreductase 248171 4529167 MAV_0242 Mycobacterium avium 104 quinone oxidoreductase YP_879534.1 247191 R 243243 CDS YP_879535.1 118465501 4526797 complement(248295..249413) 1 NC_008595.1 hypothetical protein 249413 4526797 MAV_0244 Mycobacterium avium 104 hypothetical protein YP_879535.1 248295 R 243243 CDS YP_879536.1 118464963 4528703 complement(249454..249645) 1 NC_008595.1 hypothetical protein 249645 4528703 MAV_0245 Mycobacterium avium 104 hypothetical protein YP_879536.1 249454 R 243243 CDS YP_879537.1 118466931 4527766 complement(249674..250918) 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 250918 4527766 MAV_0246 Mycobacterium avium 104 beta-lactamase YP_879537.1 249674 R 243243 CDS YP_879538.1 118466338 4528769 complement(250938..251762) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 251762 4528769 MAV_0247 Mycobacterium avium 104 enoyl-CoA hydratase YP_879538.1 250938 R 243243 CDS YP_879539.1 118462650 4529391 251777..252373 1 NC_008595.1 identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03086; hypothetical protein 252373 4529391 MAV_0248 Mycobacterium avium 104 hypothetical protein YP_879539.1 251777 D 243243 CDS YP_879540.1 118464349 4529151 complement(252454..252915) 1 NC_008595.1 hypothetical protein 252915 4529151 MAV_0249 Mycobacterium avium 104 hypothetical protein YP_879540.1 252454 R 243243 CDS YP_879541.1 118464093 4525854 complement(252926..253993) 1 NC_008595.1 identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; aminotransferase 253993 hisC 4525854 hisC Mycobacterium avium 104 aminotransferase YP_879541.1 252926 R 243243 CDS YP_879542.1 118463605 4527552 complement(254394..255593) 1 NC_008595.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 255593 4527552 MAV_0253 Mycobacterium avium 104 site-specific recombinase, phage integrase YP_879542.1 254394 R 243243 CDS YP_879543.1 118466144 4527910 255751..256011 1 NC_008595.1 identified by match to protein family HMM TIGR01764; DNA-binding protein 256011 4527910 MAV_0254 Mycobacterium avium 104 DNA-binding protein YP_879543.1 255751 D 243243 CDS YP_879544.1 118466724 4530662 complement(256081..256689) 1 NC_008595.1 hypothetical protein 256689 4530662 MAV_0255 Mycobacterium avium 104 hypothetical protein YP_879544.1 256081 R 243243 CDS YP_879545.1 118467130 4526157 complement(256769..256915) 1 NC_008595.1 hypothetical protein 256915 4526157 MAV_0256 Mycobacterium avium 104 hypothetical protein YP_879545.1 256769 R 243243 CDS YP_879546.1 118465750 4530442 complement(256997..257146) 1 NC_008595.1 hypothetical protein 257146 4530442 MAV_0257 Mycobacterium avium 104 hypothetical protein YP_879546.1 256997 R 243243 CDS YP_879547.1 118463865 4527743 complement(257171..257470) 1 NC_008595.1 hypothetical protein 257470 4527743 MAV_0258 Mycobacterium avium 104 hypothetical protein YP_879547.1 257171 R 243243 CDS YP_879548.1 118464584 4530288 complement(257485..258138) 1 NC_008595.1 hypothetical protein 258138 4530288 MAV_0259 Mycobacterium avium 104 hypothetical protein YP_879548.1 257485 R 243243 CDS YP_879549.1 118462965 4526333 complement(258151..258717) 1 NC_008595.1 hypothetical protein 258717 4526333 MAV_0260 Mycobacterium avium 104 hypothetical protein YP_879549.1 258151 R 243243 CDS YP_879550.1 118463100 4528923 complement(258789..259973) 1 NC_008595.1 hypothetical protein 259973 4528923 MAV_0261 Mycobacterium avium 104 hypothetical protein YP_879550.1 258789 R 243243 CDS YP_879551.1 118464207 4526887 complement(260039..260374) 1 NC_008595.1 chromosome partitioning protein 260374 4526887 MAV_0262 Mycobacterium avium 104 chromosome partitioning protein YP_879551.1 260039 R 243243 CDS YP_879552.1 118466553 4529102 complement(260406..261287) 1 NC_008595.1 hypothetical protein 261287 4529102 MAV_0263 Mycobacterium avium 104 hypothetical protein YP_879552.1 260406 R 243243 CDS YP_879553.1 118463267 4528132 complement(261316..263352) 1 NC_008595.1 identified by match to protein family HMM PF01580; ftsk/SpoIIIE family protein, putative 263352 4528132 MAV_0264 Mycobacterium avium 104 ftsk/SpoIIIE family protein, putative YP_879553.1 261316 R 243243 CDS YP_879554.1 118465875 4527517 complement(263356..264168) 1 NC_008595.1 hypothetical protein 264168 4527517 MAV_0265 Mycobacterium avium 104 hypothetical protein YP_879554.1 263356 R 243243 CDS YP_879555.1 118465179 4528669 264511..264810 1 NC_008595.1 identified by match to protein family HMM TIGR01764; DNA binding domain-containing protein 264810 4528669 MAV_0266 Mycobacterium avium 104 DNA binding domain-containing protein YP_879555.1 264511 D 243243 CDS YP_879556.1 118463824 4526080 264807..265031 1 NC_008595.1 hypothetical protein 265031 4526080 MAV_0267 Mycobacterium avium 104 hypothetical protein YP_879556.1 264807 D 243243 CDS YP_879557.1 118465586 4527133 265325..268261 1 NC_008595.1 hypothetical protein 268261 4527133 MAV_0268 Mycobacterium avium 104 hypothetical protein YP_879557.1 265325 D 243243 CDS YP_879558.1 118464242 4528615 268746..269240 1 NC_008595.1 hypothetical protein 269240 4528615 MAV_0269 Mycobacterium avium 104 hypothetical protein YP_879558.1 268746 D 243243 CDS YP_879559.1 118463628 4527332 269297..269698 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 269698 4527332 MAV_0270 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_879559.1 269297 D 243243 CDS YP_879560.1 118463056 4528336 269790..270074 1 NC_008595.1 identified by match to protein family HMM PF01381; DNA-binding protein 270074 4528336 MAV_0271 Mycobacterium avium 104 DNA-binding protein YP_879560.1 269790 D 243243 CDS YP_879561.1 118463101 4528924 complement(270077..270274) 1 NC_008595.1 hypothetical protein 270274 4528924 MAV_0272 Mycobacterium avium 104 hypothetical protein YP_879561.1 270077 R 243243 CDS YP_879562.1 118464094 4525855 complement(270362..270778) 1 NC_008595.1 hypothetical protein 270778 4525855 MAV_0273 Mycobacterium avium 104 hypothetical protein YP_879562.1 270362 R 243243 CDS YP_879563.1 118467018 4529488 complement(270792..273383) 1 NC_008595.1 hypothetical protein 273383 4529488 MAV_0274 Mycobacterium avium 104 hypothetical protein YP_879563.1 270792 R 243243 CDS YP_879564.1 118462638 4529378 complement(273383..275371) 1 NC_008595.1 identified by match to protein family HMM PF01555; adenine specific DNA methylase Mod 275371 4529378 MAV_0275 Mycobacterium avium 104 adenine specific DNA methylase Mod YP_879564.1 273383 R 243243 CDS YP_879565.1 118465977 4528196 275691..276152 1 NC_008595.1 hypothetical protein 276152 4528196 MAV_0276 Mycobacterium avium 104 hypothetical protein YP_879565.1 275691 D 243243 CDS YP_879566.1 118466638 4526994 276155..276499 1 NC_008595.1 hypothetical protein 276499 4526994 MAV_0277 Mycobacterium avium 104 hypothetical protein YP_879566.1 276155 D 243243 CDS YP_879567.1 118465368 4529229 complement(276509..277969) 1 NC_008595.1 hypothetical protein 277969 4529229 MAV_0278 Mycobacterium avium 104 hypothetical protein YP_879567.1 276509 R 243243 CDS YP_879568.1 118466001 4528445 complement(278017..278811) 1 NC_008595.1 identified by match to protein family HMM PF00089; trypsin domain-containing protein 278811 4528445 MAV_0279 Mycobacterium avium 104 trypsin domain-containing protein YP_879568.1 278017 R 243243 CDS YP_879569.1 118463175 4529877 278816..278962 1 NC_008595.1 hypothetical protein 278962 4529877 MAV_0280 Mycobacterium avium 104 hypothetical protein YP_879569.1 278816 D 243243 CDS YP_879570.1 118463048 4528327 complement(278976..279179) 1 NC_008595.1 hypothetical protein 279179 4528327 MAV_0281 Mycobacterium avium 104 hypothetical protein YP_879570.1 278976 R 243243 CDS YP_879571.1 118463555 4526822 280305..280772 1 NC_008595.1 identified by match to protein family HMM TIGR01764; DNA binding domain-containing protein 280772 4526822 MAV_0282 Mycobacterium avium 104 DNA binding domain-containing protein YP_879571.1 280305 D 243243 CDS YP_879572.1 118462676 4530603 281053..281202 1 NC_008595.1 hypothetical protein 281202 4530603 MAV_0283 Mycobacterium avium 104 hypothetical protein YP_879572.1 281053 D 243243 CDS YP_879573.1 118462462 4528715 281199..283997 1 NC_008595.1 hypothetical protein 283997 4528715 MAV_0284 Mycobacterium avium 104 hypothetical protein YP_879573.1 281199 D 243243 CDS YP_879574.1 118465979 4526121 complement(284492..285316) 1 NC_008595.1 hypothetical protein 285316 4526121 MAV_0285 Mycobacterium avium 104 hypothetical protein YP_879574.1 284492 R 243243 CDS YP_879575.1 118463023 4526316 285508..285789 1 NC_008595.1 carnitine racemase, putative 285789 4526316 MAV_0286 Mycobacterium avium 104 carnitine racemase, putative YP_879575.1 285508 D 243243 CDS YP_879576.1 118462497 4530693 285974..286585 1 NC_008595.1 gp6 protein 286585 4530693 MAV_0287 Mycobacterium avium 104 gp6 protein YP_879576.1 285974 D 243243 CDS YP_879577.1 118463209 4527536 286609..286875 1 NC_008595.1 identified by match to protein family HMM PF00462; glutaredoxin 286875 4527536 MAV_0288 Mycobacterium avium 104 glutaredoxin YP_879577.1 286609 D 243243 CDS YP_879578.1 118463039 4528880 286872..287255 1 NC_008595.1 hypothetical protein 287255 4528880 MAV_0289 Mycobacterium avium 104 hypothetical protein YP_879578.1 286872 D 243243 CDS YP_879579.1 118465086 4525903 287283..289778 1 NC_008595.1 hypothetical protein 289778 4525903 MAV_0290 Mycobacterium avium 104 hypothetical protein YP_879579.1 287283 D 243243 CDS YP_879580.1 118464399 4530793 complement(289849..289971) 1 NC_008595.1 hypothetical protein 289971 4530793 MAV_0291 Mycobacterium avium 104 hypothetical protein YP_879580.1 289849 R 243243 CDS YP_879581.1 118465809 4525911 290359..291492 1 NC_008595.1 identified by match to protein family HMM PF00589; integrase 291492 4525911 MAV_0292 Mycobacterium avium 104 integrase YP_879581.1 290359 D 243243 CDS YP_879582.1 118464625 4526782 complement(291493..291816) 1 NC_008595.1 hypothetical protein 291816 4526782 MAV_0293 Mycobacterium avium 104 hypothetical protein YP_879582.1 291493 R 243243 CDS YP_879583.1 118465246 4528464 complement(291813..291992) 1 NC_008595.1 hypothetical protein 291992 4528464 MAV_0294 Mycobacterium avium 104 hypothetical protein YP_879583.1 291813 R 243243 CDS YP_879584.1 118467225 4529606 292102..293013 1 NC_008595.1 hypothetical protein 293013 4529606 MAV_0295 Mycobacterium avium 104 hypothetical protein YP_879584.1 292102 D 243243 CDS YP_879585.1 118463677 4528524 293069..293629 1 NC_008595.1 hypothetical protein 293629 4528524 MAV_0296 Mycobacterium avium 104 hypothetical protein YP_879585.1 293069 D 243243 CDS YP_879586.1 118463336 4529206 293626..293958 1 NC_008595.1 hypothetical protein 293958 4529206 MAV_0297 Mycobacterium avium 104 hypothetical protein YP_879586.1 293626 D 243243 CDS YP_879587.1 118462617 4526419 293984..294226 1 NC_008595.1 hypothetical protein 294226 4526419 MAV_0298 Mycobacterium avium 104 hypothetical protein YP_879587.1 293984 D 243243 CDS YP_879588.1 118462252 4526938 294476..294892 1 NC_008595.1 hypothetical protein 294892 4526938 MAV_0299 Mycobacterium avium 104 hypothetical protein YP_879588.1 294476 D 243243 CDS YP_879589.1 118464555 4530774 complement(294941..296005) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein, putative 296005 4530774 MAV_0300 Mycobacterium avium 104 phosphotransferase enzyme family protein, putative YP_879589.1 294941 R 243243 CDS YP_879590.1 118463666 4525958 296096..297040 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 297040 4525958 MAV_0301 Mycobacterium avium 104 methyltransferase, putative, family protein YP_879590.1 296096 D 243243 CDS YP_879591.1 118465983 4526125 297208..297435 1 NC_008595.1 hypothetical protein 297435 4526125 MAV_0302 Mycobacterium avium 104 hypothetical protein YP_879591.1 297208 D 243243 CDS YP_879592.1 118465145 4529177 297457..297612 1 NC_008595.1 hypothetical protein 297612 4529177 MAV_0303 Mycobacterium avium 104 hypothetical protein YP_879592.1 297457 D 243243 CDS YP_879593.1 118466148 4527914 297688..298428 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 298428 4527914 MAV_0304 Mycobacterium avium 104 DNA-binding response regulator YP_879593.1 297688 D 243243 CDS YP_879594.1 118466581 4527371 298475..299965 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 299965 4527371 MAV_0305 Mycobacterium avium 104 sensor histidine kinase YP_879594.1 298475 D 243243 CDS YP_879595.1 118462431 4528294 complement(299967..300452) 1 NC_008595.1 identified by match to protein family HMM PF05481; lipoprotein LpqH 300452 4528294 MAV_0306 Mycobacterium avium 104 lipoprotein LpqH YP_879595.1 299967 R 243243 CDS YP_879596.1 118467075 4526453 300594..302468 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 302468 4526453 MAV_0307 Mycobacterium avium 104 metallo-beta-lactamase YP_879596.1 300594 D 243243 CDS YP_879597.1 118463218 4528792 complement(302478..303446) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-binding 303446 4528792 MAV_0308 Mycobacterium avium 104 alcohol dehydrogenase, zinc-binding YP_879597.1 302478 R 243243 CDS YP_879598.1 118463745 4528153 complement(303446..304060) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 304060 4528153 MAV_0309 Mycobacterium avium 104 TetR family transcriptional regulator YP_879598.1 303446 R 243243 CDS YP_879599.1 118466171 4526202 complement(305354..306118) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 306118 4526202 MAV_0311 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_879599.1 305354 R 243243 CDS YP_879600.1 118466657 4528096 complement(306120..307178) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 307178 4528096 MAV_0312 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_879600.1 306120 R 243243 CDS YP_879601.1 118467221 4529602 complement(307234..307917) 1 NC_008595.1 identified by match to protein family HMM PF05724; thiopurine S-methyltransferase (tpmt) superfamily protein 307917 4529602 MAV_0313 Mycobacterium avium 104 thiopurine S-methyltransferase (tpmt) superfamily protein YP_879601.1 307234 R 243243 CDS YP_879602.1 118462641 4529381 307994..308602 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase, putative 308602 4529381 MAV_0314 Mycobacterium avium 104 phosphoglycerate mutase, putative YP_879602.1 307994 D 243243 CDS YP_879603.1 118463964 4527210 308637..309689 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 309689 4527210 MAV_0316 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_879603.1 308637 D 243243 CDS YP_879604.1 118464102 4525863 complement(309686..310036) 1 NC_008595.1 hypothetical protein 310036 4525863 MAV_0315 Mycobacterium avium 104 hypothetical protein YP_879604.1 309686 R 243243 CDS YP_879605.1 118464087 4528400 310174..311082 1 NC_008595.1 identified by match to protein family HMM PF04069; quaternary amine ABC transporter substrate-binding protein 311082 4528400 MAV_0317 Mycobacterium avium 104 quaternary amine ABC transporter substrate-binding protein YP_879605.1 310174 D 243243 CDS YP_879606.1 118464676 4528371 311084..312178 1 NC_008595.1 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 312178 4528371 MAV_0318 Mycobacterium avium 104 amino acid ABC transporter ATP-binding protein YP_879606.1 311084 D 243243 CDS YP_879607.1 118464857 4527973 312178..312864 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 312864 4527973 MAV_0319 Mycobacterium avium 104 ABC transporter permease YP_879607.1 312178 D 243243 CDS YP_879608.1 118465737 4525700 312861..313577 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 313577 4525700 MAV_0320 Mycobacterium avium 104 ABC transporter permease YP_879608.1 312861 D 243243 CDS YP_879609.1 118463305 4526000 313677..314177 1 NC_008595.1 identified by match to protein family HMM PF06475; hypothetical protein 314177 4526000 MAV_0322 Mycobacterium avium 104 hypothetical protein YP_879609.1 313677 D 243243 CDS YP_879610.1 118466933 4527768 complement(314140..315084) 1 NC_008595.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 315084 4527768 MAV_0321 Mycobacterium avium 104 prephenate dehydrogenase YP_879610.1 314140 R 243243 CDS YP_879611.1 118464077 4528390 315227..315748 1 NC_008595.1 hypothetical protein 315748 4528390 MAV_0323 Mycobacterium avium 104 hypothetical protein YP_879611.1 315227 D 243243 CDS YP_879612.1 118464690 4527879 315745..316203 1 NC_008595.1 identified by match to protein family HMM PF00383; cytidine and deoxycytidylate deaminase 316203 4527879 MAV_0324 Mycobacterium avium 104 cytidine and deoxycytidylate deaminase YP_879612.1 315745 D 243243 CDS YP_879613.1 118464685 4528380 316495..317412 1 NC_008595.1 identified by match to protein family HMM PF01341; endoglucanase A 317412 4528380 MAV_0326 Mycobacterium avium 104 endoglucanase A YP_879613.1 316495 D 243243 CDS YP_879614.1 118467036 4526550 317505..317978 1 NC_008595.1 identified by match to protein family HMM PF00188; hypothetical protein 317978 4526550 MAV_0327 Mycobacterium avium 104 hypothetical protein YP_879614.1 317505 D 243243 CDS YP_879615.1 118464516 4529436 318572..318904 1 NC_008595.1 hypothetical protein 318904 4529436 MAV_0328 Mycobacterium avium 104 hypothetical protein YP_879615.1 318572 D 243243 CDS YP_879616.1 118466824 4527389 318957..320231 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 320231 4527389 MAV_0329 Mycobacterium avium 104 transposase, Mutator family protein YP_879616.1 318957 D 243243 CDS YP_879617.1 118462614 4528518 complement(322189..322707) 1 NC_008595.1 hypothetical protein 322707 4528518 MAV_0330 Mycobacterium avium 104 hypothetical protein YP_879617.1 322189 R 243243 CDS YP_879618.1 118465418 4529967 complement(322745..324382) 1 NC_008595.1 hypothetical protein 324382 4529967 MAV_0331 Mycobacterium avium 104 hypothetical protein YP_879618.1 322745 R 243243 CDS YP_879619.1 118463126 4529651 complement(324946..326079) 1 NC_008595.1 hypothetical protein 326079 4529651 MAV_0332 Mycobacterium avium 104 hypothetical protein YP_879619.1 324946 R 243243 CDS YP_879620.1 118463907 4525838 326265..326402 1 NC_008595.1 hypothetical protein 326402 4525838 MAV_0333 Mycobacterium avium 104 hypothetical protein YP_879620.1 326265 D 243243 CDS YP_879621.1 118464474 4528848 326533..326793 1 NC_008595.1 hypothetical protein 326793 4528848 MAV_0334 Mycobacterium avium 104 hypothetical protein YP_879621.1 326533 D 243243 CDS YP_879622.1 118463217 4528791 326801..328066 1 NC_008595.1 hypothetical protein 328066 4528791 MAV_0335 Mycobacterium avium 104 hypothetical protein YP_879622.1 326801 D 243243 CDS YP_879623.1 118464001 4529263 328078..329316 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 329316 4529263 MAV_0336 Mycobacterium avium 104 metallo-beta-lactamase YP_879623.1 328078 D 243243 CDS YP_879624.1 118464748 4527644 329313..329795 1 NC_008595.1 hypothetical protein 329795 4527644 MAV_0337 Mycobacterium avium 104 hypothetical protein YP_879624.1 329313 D 243243 CDS YP_879625.1 118466555 4529104 329809..330783 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 330783 4529104 MAV_0338 Mycobacterium avium 104 hypothetical protein YP_879625.1 329809 D 243243 CDS YP_879626.1 118466041 4528049 complement(330795..331451) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 331451 4528049 MAV_0339 Mycobacterium avium 104 GntR family transcriptional regulator YP_879626.1 330795 R 243243 CDS YP_879627.1 118465791 4526104 331513..332868 1 NC_008595.1 nitrilotriacetate monooxygenase component A 332868 4526104 MAV_0340 Mycobacterium avium 104 nitrilotriacetate monooxygenase component A YP_879627.1 331513 D 243243 CDS YP_879628.1 118463917 4525848 332861..334045 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 334045 4525848 MAV_0341 Mycobacterium avium 104 caib/baif family protein YP_879628.1 332861 D 243243 CDS YP_879629.1 118467078 4526378 334063..334989 1 NC_008595.1 identified by match to protein family HMM PF03328; malyl-CoA lyase 334989 4526378 MAV_0343 Mycobacterium avium 104 malyl-CoA lyase YP_879629.1 334063 D 243243 CDS YP_879630.1 118465096 4529987 complement(334986..338369) 1 NC_008595.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 338369 pyc 4529987 pyc Mycobacterium avium 104 pyruvate carboxylase YP_879630.1 334986 R 243243 CDS YP_879631.1 118463377 4528955 complement(338375..339502) 1 NC_008595.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 339502 4528955 MAV_0344 Mycobacterium avium 104 citrate synthase YP_879631.1 338375 R 243243 CDS YP_879632.1 118466506 4525589 complement(339514..340416) 1 NC_008595.1 identified by match to protein family HMM TIGR02317; methylisocitrate lyase 340416 prpB 4525589 prpB Mycobacterium avium 104 methylisocitrate lyase YP_879632.1 339514 R 243243 CDS YP_879633.1 118462314 4529632 complement(340416..341921) 1 NC_008595.1 identified by match to protein family HMM PF03972; 2-methylcitrate dehydratase 2 341921 4529632 MAV_0346 Mycobacterium avium 104 2-methylcitrate dehydratase 2 YP_879633.1 340416 R 243243 CDS YP_879634.1 118464968 4528708 342041..343465 1 NC_008595.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114; XRE family transcriptional regulator 343465 4528708 MAV_0348 Mycobacterium avium 104 XRE family transcriptional regulator YP_879634.1 342041 D 243243 CDS YP_879635.1 118462874 4527102 complement(343455..344333) 1 NC_008595.1 identified by match to protein family HMM PF00294; kinase, PfkB family protein 344333 4527102 MAV_0347 Mycobacterium avium 104 kinase, PfkB family protein YP_879635.1 343455 R 243243 CDS YP_879636.1 118463256 4528121 344443..345432 1 NC_008595.1 identified by similarity to GB:BAB40320.1; match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 345432 4528121 MAV_0349 Mycobacterium avium 104 D-isomer specific 2-hydroxyacid dehydrogenase YP_879636.1 344443 D 243243 CDS YP_879637.1 118465129 4529160 complement(345439..346035) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 346035 4529160 MAV_0350 Mycobacterium avium 104 TetR family transcriptional regulator YP_879637.1 345439 R 243243 CDS YP_879638.1 118467336 4526974 complement(346032..346805) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 346805 4526974 MAV_0351 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_879638.1 346032 R 243243 CDS YP_879639.1 118464439 4525970 complement(346802..347011) 1 NC_008595.1 lactoylglutathione lyase, putative 347011 4525970 MAV_0352 Mycobacterium avium 104 lactoylglutathione lyase, putative YP_879639.1 346802 R 243243 CDS YP_879640.1 118464182 4526492 complement(347008..348087) 1 NC_008595.1 hypothetical protein 348087 4526492 MAV_0353 Mycobacterium avium 104 hypothetical protein YP_879640.1 347008 R 243243 CDS YP_879641.1 118463604 4527551 348205..349062 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 349062 4527551 MAV_0354 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_879641.1 348205 D 243243 CDS YP_879642.1 118464426 4530247 349101..350456 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; bifunctional wax ester synthase/acyl-coadiacylglycerol acyltransferase 350456 4530247 MAV_0355 Mycobacterium avium 104 bifunctional wax ester synthase/acyl-coadiacylglycerol acyltransferase YP_879642.1 349101 D 243243 CDS YP_879643.1 118463633 4527337 350463..350948 1 NC_008595.1 identified by match to protein family HMM PF00293; nudix hydrolase 350948 4527337 MAV_0356 Mycobacterium avium 104 nudix hydrolase YP_879643.1 350463 D 243243 CDS YP_879644.1 118463258 4528123 350950..351855 1 NC_008595.1 identified by match to protein family HMM PF00561; haloalkane dehalogenase 351855 4528123 MAV_0357 Mycobacterium avium 104 haloalkane dehalogenase YP_879644.1 350950 D 243243 CDS YP_879645.1 118462523 4527666 351892..353127 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 353127 4527666 MAV_0358 Mycobacterium avium 104 cytochrome P450 YP_879645.1 351892 D 243243 CDS YP_879646.1 118467281 4527083 complement(353273..353635) 1 NC_008595.1 hypothetical protein 353635 4527083 MAV_0359 Mycobacterium avium 104 hypothetical protein YP_879646.1 353273 R 243243 CDS YP_879647.1 118467181 4530151 353728..354075 1 NC_008595.1 hypothetical protein 354075 4530151 MAV_0361 Mycobacterium avium 104 hypothetical protein YP_879647.1 353728 D 243243 CDS YP_879648.1 118463802 4525884 complement(354042..355136) 1 NC_008595.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 355136 ligC 4525884 ligC Mycobacterium avium 104 ATP-dependent DNA ligase YP_879648.1 354042 R 243243 CDS YP_879649.1 118466411 4526254 355178..356206 1 NC_008595.1 identified by match to protein family HMM TIGR02778; DNA polymerase LigD polymerase subunit 356206 ligD 4526254 ligD Mycobacterium avium 104 DNA polymerase LigD polymerase subunit YP_879649.1 355178 D 243243 CDS YP_879650.1 118465680 4525739 356245..356403 1 NC_008595.1 hypothetical protein 356403 4525739 MAV_0363 Mycobacterium avium 104 hypothetical protein YP_879650.1 356245 D 243243 CDS YP_879651.1 118465311 4526565 356608..358620 1 NC_008595.1 hypothetical protein 358620 4526565 MAV_0365 Mycobacterium avium 104 hypothetical protein YP_879651.1 356608 D 243243 CDS YP_879652.1 118466016 4529902 complement(358561..359616) 1 NC_008595.1 hypothetical protein 359616 4529902 MAV_0364 Mycobacterium avium 104 hypothetical protein YP_879652.1 358561 R 243243 CDS YP_879653.1 118466045 4528053 359623..360825 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 360825 4528053 MAV_0366 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_879653.1 359623 D 243243 CDS YP_879654.1 118465338 4526651 complement(360830..361405) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 361405 4526651 MAV_0367 Mycobacterium avium 104 TetR family transcriptional regulator YP_879654.1 360830 R 243243 CDS YP_879655.1 118463142 4527780 complement(362407..363102) 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase cutinase 363102 4527780 MAV_0369 Mycobacterium avium 104 serine esterase cutinase YP_879655.1 362407 R 243243 CDS YP_879656.1 118465088 4525905 363163..363315 1 NC_008595.1 hypothetical protein 363315 4525905 MAV_0370 Mycobacterium avium 104 hypothetical protein YP_879656.1 363163 D 243243 CDS YP_879657.1 118462589 4530210 complement(363331..364398) 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase 364398 dapB 4530210 dapB Mycobacterium avium 104 dihydrodipicolinate reductase YP_879657.1 363331 R 243243 CDS YP_879658.1 118464770 4529125 complement(364437..365573) 1 NC_008595.1 hypothetical protein 365573 4529125 MAV_0372 Mycobacterium avium 104 hypothetical protein YP_879658.1 364437 R 243243 CDS YP_879659.1 118465506 4526803 complement(365570..366904) 1 NC_008595.1 hypothetical protein 366904 4526803 MAV_0373 Mycobacterium avium 104 hypothetical protein YP_879659.1 365570 R 243243 CDS YP_879660.1 118464035 4529007 366949..367281 1 NC_008595.1 hypothetical protein 367281 4529007 MAV_0374 Mycobacterium avium 104 hypothetical protein YP_879660.1 366949 D 243243 CDS YP_879661.1 118462504 4528582 complement(367284..368666) 1 NC_008595.1 hypothetical protein 368666 4528582 MAV_0375 Mycobacterium avium 104 hypothetical protein YP_879661.1 367284 R 243243 CDS YP_879662.1 118463208 4527535 complement(368663..370351) 1 NC_008595.1 hypothetical protein 370351 4527535 MAV_0376 Mycobacterium avium 104 hypothetical protein YP_879662.1 368663 R 243243 CDS YP_879663.1 118466222 4528902 complement(370449..370907) 1 NC_008595.1 hypothetical protein 370907 4528902 MAV_0377 Mycobacterium avium 104 hypothetical protein YP_879663.1 370449 R 243243 CDS YP_879664.1 118466875 4526694 371084..371461 1 NC_008595.1 hypothetical protein 371461 4526694 MAV_0379 Mycobacterium avium 104 hypothetical protein YP_879664.1 371084 D 243243 CDS YP_879665.1 118465404 4525664 complement(371458..372291) 1 NC_008595.1 hypothetical protein 372291 4525664 MAV_0378 Mycobacterium avium 104 hypothetical protein YP_879665.1 371458 R 243243 CDS YP_879666.1 118463841 4526060 372870..374156 1 NC_008595.1 aspartate transaminase 374156 4526060 MAV_0381 Mycobacterium avium 104 aspartate transaminase YP_879666.1 372870 D 243243 CDS YP_879667.1 118462751 4527841 374305..376131 1 NC_008595.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 376131 4527841 MAV_0382 Mycobacterium avium 104 DNA polymerase III subunits gamma/tau YP_879667.1 374305 D 243243 CDS YP_879668.1 118463272 4530520 complement(376143..377453) 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 377453 4530520 MAV_0383 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase YP_879668.1 376143 R 243243 CDS YP_879669.1 118466141 4527907 complement(377450..378874) 1 NC_008595.1 identified by match to protein family HMM PF01565; FAD/FMN-containing dehydrogenase 378874 4527907 MAV_0384 Mycobacterium avium 104 FAD/FMN-containing dehydrogenase YP_879669.1 377450 R 243243 CDS YP_879670.1 118467338 4526976 378923..379360 1 NC_008595.1 KanY protein 379360 4526976 MAV_0386 Mycobacterium avium 104 KanY protein YP_879670.1 378923 D 243243 CDS YP_879671.1 118464818 4527637 complement(379357..380094) 1 NC_008595.1 identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 380094 4527637 MAV_0385 Mycobacterium avium 104 N-acetylmuramoyl-L-alanine amidase YP_879671.1 379357 R 243243 CDS YP_879672.1 118465573 4526759 380253..380579 1 NC_008595.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 380579 4526759 MAV_0387 Mycobacterium avium 104 hypothetical protein YP_879672.1 380253 D 243243 CDS YP_879673.1 118463085 4528908 380605..381216 1 NC_008595.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 381216 recR 4528908 recR Mycobacterium avium 104 recombination protein RecR YP_879673.1 380605 D 243243 CDS YP_879674.1 118466729 4530667 complement(381231..381938) 1 NC_008595.1 identified by match to protein family HMM PF07685; CobB/CobQ-like glutamine amidotransferase 381938 4530667 MAV_0389 Mycobacterium avium 104 CobB/CobQ-like glutamine amidotransferase YP_879674.1 381231 R 243243 CDS YP_879675.1 118465123 4530476 complement(381931..383181) 1 NC_008595.1 mur ligase 383181 4530476 MAV_0390 Mycobacterium avium 104 mur ligase YP_879675.1 381931 R 243243 CDS YP_879676.1 118463087 4528910 383431..384420 1 NC_008595.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 384420 4528910 MAV_0391 Mycobacterium avium 104 DNA polymerase III subunit epsilon YP_879676.1 383431 D 243243 CDS YP_879677.1 118463994 4529256 complement(384421..386220) 1 NC_008595.1 identified by match to protein family HMM PF00682; match to protein family HMM TIGR00970; 2-isopropylmalate synthase 386220 leuA 4529256 leuA Mycobacterium avium 104 2-isopropylmalate synthase YP_879677.1 384421 R 243243 CDS YP_879678.1 118466525 4527198 386513..387778 1 NC_008595.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 387778 4527198 MAV_0393 Mycobacterium avium 104 aspartate kinase YP_879678.1 386513 D 243243 CDS YP_879679.1 118465578 4526764 387779..388813 1 NC_008595.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 388813 asd 4526764 asd Mycobacterium avium 104 aspartate-semialdehyde dehydrogenase YP_879679.1 387779 D 243243 CDS YP_879680.1 118465956 4527952 388821..389969 1 NC_008595.1 hypothetical protein 389969 4527952 MAV_0395 Mycobacterium avium 104 hypothetical protein YP_879680.1 388821 D 243243 CDS YP_879681.1 118463566 4530721 390145..390579 1 NC_008595.1 hypothetical protein 390579 4530721 MAV_0396 Mycobacterium avium 104 hypothetical protein YP_879681.1 390145 D 243243 CDS YP_879682.1 118466855 4529807 390722..391240 1 NC_008595.1 hypothetical protein 391240 4529807 MAV_0397 Mycobacterium avium 104 hypothetical protein YP_879682.1 390722 D 243243 CDS YP_879683.1 118465295 4529331 391308..391970 1 NC_008595.1 hypothetical protein 391970 4529331 MAV_0398 Mycobacterium avium 104 hypothetical protein YP_879683.1 391308 D 243243 CDS YP_879684.1 118464049 4529021 392176..393486 1 NC_008595.1 identified by match to protein family HMM PF04107; glutamate--cysteine ligase 393486 4529021 MAV_0399 Mycobacterium avium 104 glutamate--cysteine ligase YP_879684.1 392176 D 243243 CDS YP_879685.1 118464531 4529451 393483..394784 1 NC_008595.1 identified by match to protein family HMM PF03781; hypothetical protein 394784 4529451 MAV_0400 Mycobacterium avium 104 hypothetical protein YP_879685.1 393483 D 243243 CDS YP_879686.1 118462630 4526432 394784..395482 1 NC_008595.1 hypothetical protein 395482 4526432 MAV_0401 Mycobacterium avium 104 hypothetical protein YP_879686.1 394784 D 243243 CDS YP_879687.1 118462386 4525929 395479..396447 1 NC_008595.1 hypothetical protein 396447 4525929 MAV_0402 Mycobacterium avium 104 hypothetical protein YP_879687.1 395479 D 243243 CDS YP_879688.1 118465026 4530075 396444..397589 1 NC_008595.1 identified by match to protein family HMM PF00266; pyridoxal-phosphate-dependent transferase 397589 4530075 MAV_0403 Mycobacterium avium 104 pyridoxal-phosphate-dependent transferase YP_879688.1 396444 D 243243 CDS YP_879689.1 118466516 4527189 complement(397593..398273) 1 NC_008595.1 identified by match to protein family HMM PF05724; thiopurine S-methyltransferase (tpmt) superfamily protein 398273 4527189 MAV_0404 Mycobacterium avium 104 thiopurine S-methyltransferase (tpmt) superfamily protein YP_879689.1 397593 R 243243 CDS YP_879690.1 118464544 4530414 complement(398284..399756) 1 NC_008595.1 CBS domain-containing protein 399756 4530414 MAV_0405 Mycobacterium avium 104 CBS domain-containing protein YP_879690.1 398284 R 243243 CDS YP_879691.1 118465403 4525663 399863..401389 1 NC_008595.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 401389 glpK 4525663 glpK Mycobacterium avium 104 glycerol kinase YP_879691.1 399863 D 243243 CDS YP_879692.1 118462822 4528636 complement(401422..402192) 1 NC_008595.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 402192 4528636 MAV_0407 Mycobacterium avium 104 PadR family transcriptional regulator YP_879692.1 401422 R 243243 CDS YP_879693.1 118464081 4528394 402344..402733 1 NC_008595.1 hypothetical protein 402733 4528394 MAV_0409 Mycobacterium avium 104 hypothetical protein YP_879693.1 402344 D 243243 CDS YP_879694.1 118465017 4530066 complement(402730..403602) 1 NC_008595.1 identified by match to protein family HMM PF06271; integral membrane protein 403602 4530066 MAV_0408 Mycobacterium avium 104 integral membrane protein YP_879694.1 402730 R 243243 CDS YP_879695.1 118466818 4527383 403683..404675 1 NC_008595.1 integral membrane protein 404675 4527383 MAV_0410 Mycobacterium avium 104 integral membrane protein YP_879695.1 403683 D 243243 CDS YP_879696.1 118466426 4530170 complement(404687..406009) 1 NC_008595.1 identified by match to protein family HMM PF01882; lipoprotein 406009 4530170 MAV_0411 Mycobacterium avium 104 lipoprotein YP_879696.1 404687 R 243243 CDS YP_879697.1 118467157 4527588 complement(406006..406989) 1 NC_008595.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728; ATPase 406989 4527588 MAV_0412 Mycobacterium avium 104 ATPase YP_879697.1 406006 R 243243 CDS YP_879698.1 118462405 4525715 complement(406986..408119) 1 NC_008595.1 hypothetical protein 408119 4525715 MAV_0413 Mycobacterium avium 104 hypothetical protein YP_879698.1 406986 R 243243 CDS YP_879699.1 118462573 4528632 complement(408119..408772) 1 NC_008595.1 hypothetical protein 408772 4528632 MAV_0414 Mycobacterium avium 104 hypothetical protein YP_879699.1 408119 R 243243 CDS YP_879700.1 118462736 4527807 complement(408797..410053) 1 NC_008595.1 hypothetical protein 410053 4527807 MAV_0415 Mycobacterium avium 104 hypothetical protein YP_879700.1 408797 R 243243 CDS YP_879701.1 118465492 4526788 410052..410516 1 NC_008595.1 identified by match to protein family HMM PF02637; GatB/Yqey domain-containing protein 410516 4526788 MAV_0416 Mycobacterium avium 104 GatB/Yqey domain-containing protein YP_879701.1 410052 D 243243 CDS YP_879702.1 118463735 4528143 complement(410526..412238) 1 NC_008595.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; elongation factor Tu GTP binding domain-containing protein 412238 4528143 MAV_0417 Mycobacterium avium 104 elongation factor Tu GTP binding domain-containing protein YP_879702.1 410526 R 243243 CDS YP_879703.1 118464757 4527653 complement(412226..413506) 1 NC_008595.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 413506 selA 4527653 selA Mycobacterium avium 104 selenocysteine synthase YP_879703.1 412226 R 243243 CDS YP_879704.1 118465144 4529176 413668..414660 1 NC_008595.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00476; selenide, water dikinase 414660 selD 4529176 selD Mycobacterium avium 104 selenide, water dikinase YP_879704.1 413668 D 243243 CDS YP_879705.1 118466615 4526852 414733..415314 1 NC_008595.1 identified by match to protein family HMM PF04879; molybdopterin oxidoreductase Fe4S4 region 415314 4526852 MAV_0421 Mycobacterium avium 104 molybdopterin oxidoreductase Fe4S4 region YP_879705.1 414733 D 243243 CDS YP_879706.1 118465566 4526752 415384..418047 1 NC_008595.1 identified by match to protein family HMM PF01568; formate dehydrogenase, alpha subunit 418047 4526752 MAV_0422 Mycobacterium avium 104 formate dehydrogenase, alpha subunit YP_879706.1 415384 D 243243 CDS YP_879707.1 118466276 4527828 418029..419021 1 NC_008595.1 identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 419021 4527828 MAV_0423 Mycobacterium avium 104 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_879707.1 418029 D 243243 CDS YP_879708.1 118466960 4530272 419018..420103 1 NC_008595.1 identified by match to protein family HMM PF03916; polysulphide reductase 420103 4530272 MAV_0424 Mycobacterium avium 104 polysulphide reductase YP_879708.1 419018 D 243243 CDS YP_879709.1 118462806 4529026 420128..421138 1 NC_008595.1 identified by match to protein family HMM PF00296; dehydrogenase 421138 4529026 MAV_0425 Mycobacterium avium 104 dehydrogenase YP_879709.1 420128 D 243243 CDS YP_879710.1 118463379 4528957 421176..421718 1 NC_008595.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; intracellular protease, PfpI family protein 421718 4528957 MAV_0426 Mycobacterium avium 104 intracellular protease, PfpI family protein YP_879710.1 421176 D 243243 CDS YP_879711.1 118463025 4526318 421829..422518 1 NC_008595.1 identified by match to protein family HMM PF01170; match to protein family HMM PF05175; match to protein family HMM TIGR00537; methylase, putative 422518 4526318 MAV_0427 Mycobacterium avium 104 methylase, putative YP_879711.1 421829 D 243243 CDS YP_879712.1 118462551 4530552 complement(422532..422672) 1 NC_008595.1 hypothetical protein 422672 4530552 MAV_0428 Mycobacterium avium 104 hypothetical protein YP_879712.1 422532 R 243243 CDS YP_879713.1 118463888 4530565 complement(422696..423727) 1 NC_008595.1 hypothetical protein 423727 4530565 MAV_0429 Mycobacterium avium 104 hypothetical protein YP_879713.1 422696 R 243243 CDS YP_879714.1 118463143 4527781 complement(423770..425980) 1 NC_008595.1 identified by match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF07228; match to protein family HMM TIGR00229; stage II sporulation protein E (SpoIIE) 425980 4527781 MAV_0430 Mycobacterium avium 104 stage II sporulation protein E (SpoIIE) YP_879714.1 423770 R 243243 CDS YP_879715.1 118465024 4530073 complement(425977..426549) 1 NC_008595.1 identified by match to protein family HMM PF07228; stage II sporulation protein E (SpoIIE), putative 426549 4530073 MAV_0431 Mycobacterium avium 104 stage II sporulation protein E (SpoIIE), putative YP_879715.1 425977 R 243243 CDS YP_879716.1 118464279 4528234 complement(426596..427006) 1 NC_008595.1 identified by match to protein family HMM PF02518; serine/threonine protein kinase 427006 4528234 MAV_0432 Mycobacterium avium 104 serine/threonine protein kinase YP_879716.1 426596 R 243243 CDS YP_879717.1 118462733 4527804 complement(426996..427385) 1 NC_008595.1 identified by match to protein family HMM PF01740; antagonist protein RsbS 427385 4527804 MAV_0433 Mycobacterium avium 104 antagonist protein RsbS YP_879717.1 426996 R 243243 CDS YP_879718.1 118463478 4525531 complement(427408..428310) 1 NC_008595.1 identified by match to protein family HMM PF01740; anti-anti-sigma factor 428310 4525531 MAV_0434 Mycobacterium avium 104 anti-anti-sigma factor YP_879718.1 427408 R 243243 CDS YP_879719.1 118462796 4525765 428508..428849 1 NC_008595.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; anti-anti-sigma factor 428849 4525765 MAV_0435 Mycobacterium avium 104 anti-anti-sigma factor YP_879719.1 428508 D 243243 CDS YP_879720.1 118462353 4527980 428894..429403 1 NC_008595.1 hypothetical protein 429403 4527980 MAV_0436 Mycobacterium avium 104 hypothetical protein YP_879720.1 428894 D 243243 CDS YP_879721.1 118464670 4528365 complement(429414..430046) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; hydrolase 430046 4528365 MAV_0437 Mycobacterium avium 104 hydrolase YP_879721.1 429414 R 243243 CDS YP_879722.1 118463959 4527205 430269..430580 1 NC_008595.1 hypothetical protein 430580 4527205 MAV_0438 Mycobacterium avium 104 hypothetical protein YP_879722.1 430269 D 243243 CDS YP_879723.1 118465838 4525510 431106..431699 1 NC_008595.1 identified by match to protein family HMM PF04471; restriction endonuclease 431699 4525510 MAV_0440 Mycobacterium avium 104 restriction endonuclease YP_879723.1 431106 D 243243 CDS YP_879724.1 118462993 4530623 complement(431749..432438) 1 NC_008595.1 identified by match to protein family HMM PF01590; match to protein family HMM PF03861; ANTAR domain-containing protein 432438 4530623 MAV_0441 Mycobacterium avium 104 ANTAR domain-containing protein YP_879724.1 431749 R 243243 CDS YP_879725.1 118463707 4530594 432641..433252 1 NC_008595.1 identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03086; hypothetical protein 433252 4530594 MAV_0442 Mycobacterium avium 104 hypothetical protein YP_879725.1 432641 D 243243 CDS YP_879726.1 118467280 4527082 complement(433405..434508) 1 NC_008595.1 identified by match to protein family HMM PF00291; cysteine synthase/cystathionine beta-synthase 434508 4527082 MAV_0444 Mycobacterium avium 104 cysteine synthase/cystathionine beta-synthase YP_879726.1 433405 R 243243 CDS YP_879727.1 118462226 4525563 complement(434505..435518) 1 NC_008595.1 identified by match to protein family HMM PF00149; secreted protein 435518 4525563 MAV_0445 Mycobacterium avium 104 secreted protein YP_879727.1 434505 R 243243 CDS YP_879728.1 118466011 4528456 complement(435576..437936) 1 NC_008595.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM PF03793; transglycosylase 437936 4528456 MAV_0446 Mycobacterium avium 104 transglycosylase YP_879728.1 435576 R 243243 CDS YP_879729.1 118466521 4527194 438507..438719 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB 438719 4527194 MAV_0447 Mycobacterium avium 104 transcription factor WhiB YP_879729.1 438507 D 243243 CDS YP_879730.1 118464440 4525971 complement(438782..439897) 1 NC_008595.1 identified by match to protein family HMM PF02374; anion-transporting ATPase 439897 4525971 MAV_0448 Mycobacterium avium 104 anion-transporting ATPase YP_879730.1 438782 R 243243 CDS YP_879731.1 118464537 4530407 complement(439921..440892) 1 NC_008595.1 identified by match to protein family HMM PF02374; anion-transporting ATPase 440892 4530407 MAV_0449 Mycobacterium avium 104 anion-transporting ATPase YP_879731.1 439921 R 243243 CDS YP_879732.1 118465261 4527282 441011..441172 1 NC_008595.1 hypothetical protein 441172 4527282 MAV_0450 Mycobacterium avium 104 hypothetical protein YP_879732.1 441011 D 243243 CDS YP_879733.1 118467024 4526536 441173..441649 1 NC_008595.1 identified by match to protein family HMM PF01042; translation initiation inhibitor 441649 4526536 MAV_0451 Mycobacterium avium 104 translation initiation inhibitor YP_879733.1 441173 D 243243 CDS YP_879734.1 118466139 4527905 441646..442449 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 442449 4527905 MAV_0452 Mycobacterium avium 104 metallo-beta-lactamase YP_879734.1 441646 D 243243 CDS YP_879735.1 118465514 4528931 complement(442682..443356) 1 NC_008595.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator protein 443356 4528931 MAV_0453 Mycobacterium avium 104 Crp/Fnr family transcriptional regulator protein YP_879735.1 442682 R 243243 CDS YP_879736.1 118465953 4527949 complement(443461..443841) 1 NC_008595.1 hypothetical protein 443841 4527949 MAV_0454 Mycobacterium avium 104 hypothetical protein YP_879736.1 443461 R 243243 CDS YP_879737.1 118464775 4529130 444012..444710 1 NC_008595.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 444710 nth 4529130 nth Mycobacterium avium 104 endonuclease III YP_879737.1 444012 D 243243 CDS YP_879738.1 118463887 4530564 444735..445403 1 NC_008595.1 hypothetical protein 445403 4530564 MAV_0456 Mycobacterium avium 104 hypothetical protein YP_879738.1 444735 D 243243 CDS YP_879739.1 118463110 4527172 445433..446251 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, nudix family protein 446251 4527172 MAV_0457 Mycobacterium avium 104 hydrolase, nudix family protein YP_879739.1 445433 D 243243 CDS YP_879740.1 118465000 4526266 446248..447456 1 NC_008595.1 identified by match to protein family HMM PF00089; match to protein family HMM PF02674; serine protease 447456 4526266 MAV_0459 Mycobacterium avium 104 serine protease YP_879740.1 446248 D 243243 CDS YP_879741.1 118462401 4525945 complement(447449..448414) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 448414 4525945 MAV_0458 Mycobacterium avium 104 alpha/beta hydrolase YP_879741.1 447449 R 243243 CDS YP_879742.1 118467139 4527153 complement(448415..448954) 1 NC_008595.1 identified by match to protein family HMM PF07332; hypothetical protein 448954 4527153 MAV_0460 Mycobacterium avium 104 hypothetical protein YP_879742.1 448415 R 243243 CDS YP_879743.1 118466911 4529456 449175..449846 1 NC_008595.1 hypothetical protein 449846 4529456 MAV_0461 Mycobacterium avium 104 hypothetical protein YP_879743.1 449175 D 243243 CDS YP_879744.1 118466201 4530191 complement(449938..451890) 1 NC_008595.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 451890 acsA 4530191 acsA Mycobacterium avium 104 acetyl-CoA synthetase YP_879744.1 449938 R 243243 CDS YP_879745.1 118463452 4529694 452005..452547 1 NC_008595.1 hypothetical protein 452547 4529694 MAV_0463 Mycobacterium avium 104 hypothetical protein YP_879745.1 452005 D 243243 CDS YP_879746.1 118462732 4527803 452654..454258 1 NC_008595.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein, family protein 5 454258 4527803 MAV_0464 Mycobacterium avium 104 extracellular solute-binding protein, family protein 5 YP_879746.1 452654 D 243243 CDS YP_879747.1 118465332 4526528 454260..455186 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 455186 dppB 4526528 dppB Mycobacterium avium 104 ABC transporter permease YP_879747.1 454260 D 243243 CDS YP_879748.1 118464640 4528975 455179..456054 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 456054 dppC 4528975 dppC Mycobacterium avium 104 ABC transporter permease YP_879748.1 455179 D 243243 CDS YP_879749.1 118466441 4527114 456042..457697 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 457697 dppD 4527114 dppD Mycobacterium avium 104 ABC transporter ATP-binding protein YP_879749.1 456042 D 243243 CDS YP_879750.1 118465103 4529994 457714..458445 1 NC_008595.1 hypothetical protein 458445 4529994 MAV_0468 Mycobacterium avium 104 hypothetical protein YP_879750.1 457714 D 243243 CDS YP_879751.1 118462359 4527987 complement(458911..459768) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; HAD-superfamily protein subfamily protein IB hydrolase 459768 4527987 MAV_0469 Mycobacterium avium 104 HAD-superfamily protein subfamily protein IB hydrolase YP_879751.1 458911 R 243243 CDS YP_879752.1 118466891 4528404 460281..461333 1 NC_008595.1 hypothetical protein 461333 4528404 MAV_0470 Mycobacterium avium 104 hypothetical protein YP_879752.1 460281 D 243243 CDS YP_879753.1 118466310 4528352 461330..462418 1 NC_008595.1 identified by match to protein family HMM PF00437; Type II/IV secretion system protein 462418 4528352 MAV_0471 Mycobacterium avium 104 Type II/IV secretion system protein YP_879753.1 461330 D 243243 CDS YP_879754.1 118462914 4528177 462391..462666 1 NC_008595.1 hypothetical protein 462666 4528177 MAV_0472 Mycobacterium avium 104 hypothetical protein YP_879754.1 462391 D 243243 CDS YP_879755.1 118463271 4528137 462660..463934 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 463934 4528137 MAV_0473 Mycobacterium avium 104 transposase, Mutator family protein YP_879755.1 462660 D 243243 CDS YP_879756.1 118464882 4529611 complement(464148..464795) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 464795 4529611 MAV_0474 Mycobacterium avium 104 TetR family transcriptional regulator YP_879756.1 464148 R 243243 CDS YP_879757.1 118467014 4529484 complement(464814..465872) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 465872 4529484 MAV_0475 Mycobacterium avium 104 amidohydrolase YP_879757.1 464814 R 243243 CDS YP_879758.1 118464705 4527894 complement(465869..466309) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 466309 4527894 MAV_0476 Mycobacterium avium 104 hypothetical protein YP_879758.1 465869 R 243243 CDS YP_879759.1 118465565 4526751 complement(466359..467552) 1 NC_008595.1 lipid-transfer protein 467552 4526751 MAV_0477 Mycobacterium avium 104 lipid-transfer protein YP_879759.1 466359 R 243243 CDS YP_879760.1 118463214 4527541 complement(467549..469909) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 469909 4527541 MAV_0478 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_879760.1 467549 R 243243 CDS YP_879761.1 118462824 4528638 470026..470883 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; carveol dehydrogenase 470883 4528638 MAV_0479 Mycobacterium avium 104 carveol dehydrogenase YP_879761.1 470026 D 243243 CDS YP_879762.1 118462910 4528173 470979..471905 1 NC_008595.1 hypothetical protein 471905 4528173 MAV_0480 Mycobacterium avium 104 hypothetical protein YP_879762.1 470979 D 243243 CDS YP_879763.1 118462508 4528586 complement(471929..472915) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 472915 4528586 MAV_0481 Mycobacterium avium 104 amidohydrolase YP_879763.1 471929 R 243243 CDS YP_879764.1 118463055 4528335 complement(472964..473845) 1 NC_008595.1 identified by match to protein family HMM PF00248; oxidoreductase YdbC 473845 4528335 MAV_0482 Mycobacterium avium 104 oxidoreductase YdbC YP_879764.1 472964 R 243243 CDS YP_879765.1 118462528 4527671 complement(473857..474210) 1 NC_008595.1 identified by match to protein family HMM PF03992; monooxygenase 474210 4527671 MAV_0483 Mycobacterium avium 104 monooxygenase YP_879765.1 473857 R 243243 CDS YP_879766.1 118464395 4528284 complement(474234..475121) 1 NC_008595.1 cyclase 475121 4528284 MAV_0484 Mycobacterium avium 104 cyclase YP_879766.1 474234 R 243243 CDS YP_879767.1 118463525 4526830 475203..475637 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 475637 4526830 MAV_0485 Mycobacterium avium 104 MarR family transcriptional regulator YP_879767.1 475203 D 243243 CDS YP_879768.1 118466090 4527358 complement(475656..476009) 1 NC_008595.1 hypothetical protein 476009 4527358 MAV_0486 Mycobacterium avium 104 hypothetical protein YP_879768.1 475656 R 243243 CDS YP_879769.1 118465396 4525656 complement(476026..476748) 1 NC_008595.1 identified by match to protein family HMM PF01738; dienelactone hydrolase 476748 4525656 MAV_0487 Mycobacterium avium 104 dienelactone hydrolase YP_879769.1 476026 R 243243 CDS YP_879770.1 118467303 4530295 complement(476745..477392) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 477392 4530295 MAV_0488 Mycobacterium avium 104 transcriptional regulator YP_879770.1 476745 R 243243 CDS YP_879771.1 118466399 4526241 477488..477916 1 NC_008595.1 identified by match to protein family HMM PF03928; GlcG protein 477916 4526241 MAV_0489 Mycobacterium avium 104 GlcG protein YP_879771.1 477488 D 243243 CDS YP_879772.1 118464074 4528387 477949..478800 1 NC_008595.1 identified by match to protein family HMM PF03328; HpcH/HpaI aldolase 478800 4528387 MAV_0490 Mycobacterium avium 104 HpcH/HpaI aldolase YP_879772.1 477949 D 243243 CDS YP_879773.1 118464637 4528972 478831..479370 1 NC_008595.1 hypothetical protein 479370 4528972 MAV_0491 Mycobacterium avium 104 hypothetical protein YP_879773.1 478831 D 243243 CDS YP_879774.1 118463595 4529781 479394..480899 1 NC_008595.1 identified by match to protein family HMM PF00135; para-nitrobenzyl esterase 480899 4529781 MAV_0492 Mycobacterium avium 104 para-nitrobenzyl esterase YP_879774.1 479394 D 243243 CDS YP_879775.1 118464167 4526477 480951..481364 1 NC_008595.1 identified by match to protein family HMM PF07366; hypothetical protein 481364 4526477 MAV_0493 Mycobacterium avium 104 hypothetical protein YP_879775.1 480951 D 243243 CDS YP_879776.1 118463797 4525879 complement(481425..481814) 1 NC_008595.1 hypothetical protein 481814 4525879 MAV_0494 Mycobacterium avium 104 hypothetical protein YP_879776.1 481425 R 243243 CDS YP_879777.1 118463859 4529958 481845..483059 1 NC_008595.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; transposase IS116/IS110/IS902 483059 4529958 MAV_0496 Mycobacterium avium 104 transposase IS116/IS110/IS902 YP_879777.1 481845 D 243243 CDS YP_879778.1 118467144 4527158 complement(483932..484207) 1 NC_008595.1 transposase 484207 4527158 MAV_0497 Mycobacterium avium 104 transposase YP_879778.1 483932 R 243243 CDS YP_879779.1 118464335 4529840 484191..484646 1 NC_008595.1 ISAfe2, transposase 484646 4529840 MAV_0498 Mycobacterium avium 104 ISAfe2, transposase YP_879779.1 484191 D 243243 CDS YP_879780.1 118464007 4529269 484989..485357 1 NC_008595.1 hypothetical protein 485357 4529269 MAV_0499 Mycobacterium avium 104 hypothetical protein YP_879780.1 484989 D 243243 CDS YP_879781.1 118462425 4528288 485366..486772 1 NC_008595.1 hypothetical protein 486772 4528288 MAV_0500 Mycobacterium avium 104 hypothetical protein YP_879781.1 485366 D 243243 CDS YP_879782.1 118466007 4528451 486787..487305 1 NC_008595.1 hypothetical protein 487305 4528451 MAV_0501 Mycobacterium avium 104 hypothetical protein YP_879782.1 486787 D 243243 CDS YP_879783.1 118465460 4526228 487350..487658 1 NC_008595.1 hypothetical protein 487658 4526228 MAV_0502 Mycobacterium avium 104 hypothetical protein YP_879783.1 487350 D 243243 CDS YP_879784.1 118465704 4530326 complement(487796..488134) 1 NC_008595.1 transposase 488134 4530326 MAV_0503 Mycobacterium avium 104 transposase YP_879784.1 487796 R 243243 CDS YP_879785.1 118466117 4529750 complement(488194..490182) 1 NC_008595.1 identified by match to protein family HMM PF00589; transposase 490182 4529750 MAV_0504 Mycobacterium avium 104 transposase YP_879785.1 488194 R 243243 CDS YP_879786.1 118465459 4526227 complement(490409..491614) 1 NC_008595.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; transposase 491614 4526227 MAV_0505 Mycobacterium avium 104 transposase YP_879786.1 490409 R 243243 CDS YP_879787.1 118466355 4530495 complement(491628..492851) 1 NC_008595.1 identified by match to protein family HMM PF06114; DNA-binding protein 492851 4530495 MAV_0506 Mycobacterium avium 104 DNA-binding protein YP_879787.1 491628 R 243243 CDS YP_879788.1 118465641 4526166 complement(492919..493602) 1 NC_008595.1 hypothetical protein 493602 4526166 MAV_0507 Mycobacterium avium 104 hypothetical protein YP_879788.1 492919 R 243243 CDS YP_879789.1 118466792 4529350 493805..493978 1 NC_008595.1 TrbB protein 493978 4529350 MAV_0508 Mycobacterium avium 104 TrbB protein YP_879789.1 493805 D 243243 CDS YP_879790.1 118466209 4528888 493975..494778 1 NC_008595.1 identified by match to protein family HMM PF00482; type II secretion system protein F 494778 4528888 MAV_0509 Mycobacterium avium 104 type II secretion system protein F YP_879790.1 493975 D 243243 CDS YP_879791.1 118463862 4527740 494801..495388 1 NC_008595.1 identified by match to protein family HMM PF00482; type II secretion system protein F 495388 4527740 MAV_0510 Mycobacterium avium 104 type II secretion system protein F YP_879791.1 494801 D 243243 CDS YP_879792.1 118464981 4527473 495407..495607 1 NC_008595.1 hypothetical protein 495607 4527473 MAV_0511 Mycobacterium avium 104 hypothetical protein YP_879792.1 495407 D 243243 CDS YP_879793.1 118467298 4527257 495664..495933 1 NC_008595.1 hypothetical protein 495933 4527257 MAV_0512 Mycobacterium avium 104 hypothetical protein YP_879793.1 495664 D 243243 CDS YP_879794.1 118466120 4529753 495965..496258 1 NC_008595.1 hypothetical protein 496258 4529753 MAV_0514 Mycobacterium avium 104 hypothetical protein YP_879794.1 495965 D 243243 CDS YP_879795.1 118464644 4528979 complement(496255..497241) 1 NC_008595.1 hypothetical protein 497241 4528979 MAV_0513 Mycobacterium avium 104 hypothetical protein YP_879795.1 496255 R 243243 CDS YP_879796.1 118465087 4525904 complement(497375..499705) 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent rna helicase, dead/deah box family protein 499705 4525904 MAV_0515 Mycobacterium avium 104 ATP-dependent rna helicase, dead/deah box family protein YP_879796.1 497375 R 243243 CDS YP_879797.1 118464580 4530284 499954..500157 1 NC_008595.1 identified by match to protein family HMM PF00313; hypothetical protein 500157 4530284 MAV_0516 Mycobacterium avium 104 hypothetical protein YP_879797.1 499954 D 243243 CDS YP_879798.1 118464759 4527655 500346..500936 1 NC_008595.1 hypothetical protein 500936 4527655 MAV_0517 Mycobacterium avium 104 hypothetical protein YP_879798.1 500346 D 243243 CDS YP_879799.1 118463766 4528010 501141..503939 1 NC_008595.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 503939 topA 4528010 topA Mycobacterium avium 104 DNA topoisomerase I YP_879799.1 501141 D 243243 CDS YP_879800.1 118465478 4527231 complement(503936..505540) 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF00672; adenylate cyclase, family protein 3 505540 4527231 MAV_0518 Mycobacterium avium 104 adenylate cyclase, family protein 3 YP_879800.1 503936 R 243243 CDS YP_879801.1 118465813 4525915 505735..506901 1 NC_008595.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 506901 4525915 MAV_0520 Mycobacterium avium 104 DNA polymerase III subunit delta' YP_879801.1 505735 D 243243 CDS YP_879802.1 118467239 4529796 complement(507099..508841) 1 NC_008595.1 hypothetical protein 508841 4529796 MAV_0522 Mycobacterium avium 104 hypothetical protein YP_879802.1 507099 R 243243 CDS YP_879803.1 118466650 4528088 508882..509823 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; nucleoside-diphosphate-sugar epimerase 509823 4528088 MAV_0524 Mycobacterium avium 104 nucleoside-diphosphate-sugar epimerase YP_879803.1 508882 D 243243 CDS YP_879804.1 118462924 4526015 complement(509820..510161) 1 NC_008595.1 hypothetical protein 510161 4526015 MAV_0523 Mycobacterium avium 104 hypothetical protein YP_879804.1 509820 R 243243 CDS YP_879805.1 118462371 4529183 complement(510158..510823) 1 NC_008595.1 identified by match to protein family HMM PF00535; glycosyl transferase 510823 4529183 MAV_0525 Mycobacterium avium 104 glycosyl transferase YP_879805.1 510158 R 243243 CDS YP_879806.1 118466766 4530761 complement(510895..512145) 1 NC_008595.1 hypothetical protein 512145 4530761 MAV_0526 Mycobacterium avium 104 hypothetical protein YP_879806.1 510895 R 243243 CDS YP_879807.1 118463569 4530724 512273..513361 1 NC_008595.1 identified by match to protein family HMM PF04332; hypothetical protein 513361 4530724 MAV_0528 Mycobacterium avium 104 hypothetical protein YP_879807.1 512273 D 243243 CDS YP_879808.1 118465582 4527129 complement(513342..513830) 1 NC_008595.1 identified by match to protein family HMM PF00719; inorganic pyrophosphatase 513830 ppa 4527129 ppa Mycobacterium avium 104 inorganic pyrophosphatase YP_879808.1 513342 R 243243 CDS YP_879809.1 118464533 4530403 513985..515337 1 NC_008595.1 identified by match to protein family HMM PF02113; match to protein family HMM TIGR00666; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 515337 dacB 4530403 dacB Mycobacterium avium 104 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_879809.1 513985 D 243243 CDS YP_879810.1 118462889 4527496 515334..516407 1 NC_008595.1 hypothetical protein 516407 4527496 MAV_0530 Mycobacterium avium 104 hypothetical protein YP_879810.1 515334 D 243243 CDS YP_879811.1 118462421 4525731 516386..517348 1 NC_008595.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; tRNA(Ile)-lysidine synthetase 517348 tilS 4525731 tilS Mycobacterium avium 104 tRNA(Ile)-lysidine synthetase YP_879811.1 516386 D 243243 CDS YP_879812.1 118466495 4525578 517399..518010 1 NC_008595.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 518010 hpt 4525578 hpt Mycobacterium avium 104 hypoxanthine phosphoribosyltransferase YP_879812.1 517399 D 243243 CDS YP_879813.1 118467102 4526363 complement(518018..518767) 1 NC_008595.1 identified by match to protein family HMM PF04402; LpqG protein 518767 4526363 MAV_0533 Mycobacterium avium 104 LpqG protein YP_879813.1 518018 R 243243 CDS YP_879814.1 118465402 4525662 519084..519383 1 NC_008595.1 identified by match to protein family HMM PF00934; PE family protein 519383 4525662 MAV_0534 Mycobacterium avium 104 PE family protein YP_879814.1 519084 D 243243 CDS YP_879815.1 118466000 4528444 519393..520658 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 520658 4528444 MAV_0535 Mycobacterium avium 104 PPE family protein YP_879815.1 519393 D 243243 CDS YP_879816.1 118466519 4527192 complement(520668..522248) 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 522248 4527192 MAV_0536 Mycobacterium avium 104 hypothetical protein YP_879816.1 520668 R 243243 CDS YP_879817.1 118465339 4526652 complement(522278..523291) 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 523291 4526652 MAV_0537 Mycobacterium avium 104 zinc-binding dehydrogenase YP_879817.1 522278 R 243243 CDS YP_879818.1 118466042 4528050 complement(523291..524478) 1 NC_008595.1 identified by match to protein family HMM PF00296; limonene 1,2-monooxygenase 524478 4528050 MAV_0538 Mycobacterium avium 104 limonene 1,2-monooxygenase YP_879818.1 523291 R 243243 CDS YP_879819.1 118466431 4530175 complement(524475..525404) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 525404 4530175 MAV_0539 Mycobacterium avium 104 alpha/beta hydrolase YP_879819.1 524475 R 243243 CDS YP_879820.1 118467187 4530158 525544..525957 1 NC_008595.1 identified by match to protein family HMM PF00903; dioxygenase 525957 4530158 MAV_0540 Mycobacterium avium 104 dioxygenase YP_879820.1 525544 D 243243 CDS YP_879821.1 118463070 4527569 526099..526218 1 NC_008595.1 hypothetical protein 526218 4527569 MAV_0541 Mycobacterium avium 104 hypothetical protein YP_879821.1 526099 D 243243 CDS YP_879822.1 118463779 4530130 526345..528744 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241; ATP-dependent metallopeptidase HflB 528744 hflB 4530130 hflB Mycobacterium avium 104 ATP-dependent metallopeptidase HflB YP_879822.1 526345 D 243243 CDS YP_879823.1 118464289 4529577 528761..529375 1 NC_008595.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 529375 folE 4529577 folE Mycobacterium avium 104 GTP cyclohydrolase I YP_879823.1 528761 D 243243 CDS YP_879824.1 118464913 4530748 529404..530198 1 NC_008595.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 530198 folP 4530748 folP Mycobacterium avium 104 dihydropteroate synthase YP_879824.1 529404 D 243243 CDS YP_879825.1 118466046 4528054 530191..530592 1 NC_008595.1 identified by match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 530592 folB 4528054 folB Mycobacterium avium 104 dihydroneopterin aldolase YP_879825.1 530191 D 243243 CDS YP_879826.1 118464375 4530518 530589..531137 1 NC_008595.1 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 531137 folK 4530518 folK Mycobacterium avium 104 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_879826.1 530589 D 243243 CDS YP_879827.1 118463545 4526812 531137..531613 1 NC_008595.1 hypothetical protein 531613 4526812 MAV_0548 Mycobacterium avium 104 hypothetical protein YP_879827.1 531137 D 243243 CDS YP_879828.1 118464202 4529313 complement(531610..531816) 1 NC_008595.1 hypothetical protein 531816 4529313 MAV_0547 Mycobacterium avium 104 hypothetical protein YP_879828.1 531610 R 243243 CDS YP_879829.1 118464078 4528391 531824..533089 1 NC_008595.1 hypothetical protein 533089 4528391 MAV_0549 Mycobacterium avium 104 hypothetical protein YP_879829.1 531824 D 243243 CDS YP_879830.1 118463044 4528885 533205..534116 1 NC_008595.1 chalcone/stilbene synthase 534116 4528885 MAV_0550 Mycobacterium avium 104 chalcone/stilbene synthase YP_879830.1 533205 D 243243 CDS YP_879831.1 118462570 4528629 534113..535039 1 NC_008595.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 535039 panC 4528629 panC Mycobacterium avium 104 pantoate--beta-alanine ligase YP_879831.1 534113 D 243243 CDS YP_879832.1 118466952 4530264 535039..535470 1 NC_008595.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 535470 panD 4530264 panD Mycobacterium avium 104 aspartate alpha-decarboxylase YP_879832.1 535039 D 243243 CDS YP_879833.1 118466299 4529546 535473..536288 1 NC_008595.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 536288 4529546 MAV_0553 Mycobacterium avium 104 pantothenate kinase YP_879833.1 535473 D 243243 CDS YP_879834.1 118465579 4526765 536335..537834 1 NC_008595.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 537834 lysS 4526765 lysS Mycobacterium avium 104 lysyl-tRNA synthetase YP_879834.1 536335 D 243243 CDS YP_879835.1 118464834 4529739 537990..538316 1 NC_008595.1 Lsr2 protein 538316 4529739 MAV_0555 Mycobacterium avium 104 Lsr2 protein YP_879835.1 537990 D 243243 CDS YP_879836.1 118466434 4527107 538716..541184 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence ClpC/mecB 541184 4527107 MAV_0556 Mycobacterium avium 104 negative regulator of genetic competence ClpC/mecB YP_879836.1 538716 D 243243 CDS YP_879837.1 118464200 4529311 541373..541588 1 NC_008595.1 hypothetical protein 541588 4529311 MAV_0557 Mycobacterium avium 104 hypothetical protein YP_879837.1 541373 D 243243 CDS YP_879838.1 118462469 4528723 541604..542380 1 NC_008595.1 hypothetical protein 542380 4528723 MAV_0558 Mycobacterium avium 104 hypothetical protein YP_879838.1 541604 D 243243 CDS YP_879839.1 118464180 4526490 542428..542925 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase, putative 542925 4526490 MAV_0559 Mycobacterium avium 104 phosphoglycerate mutase, putative YP_879839.1 542428 D 243243 CDS YP_879840.1 118463614 4527561 543119..544558 1 NC_008595.1 identified by match to protein family HMM PF03055; carotenoid oxygenase 544558 4527561 MAV_0560 Mycobacterium avium 104 carotenoid oxygenase YP_879840.1 543119 D 243243 CDS YP_879841.1 118463017 4526310 complement(544571..545884) 1 NC_008595.1 LpqF protein 545884 4526310 MAV_0561 Mycobacterium avium 104 LpqF protein YP_879841.1 544571 R 243243 CDS YP_879842.1 118462461 4528714 complement(545913..546221) 1 NC_008595.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase domain-containing protein 546221 4528714 MAV_0562 Mycobacterium avium 104 antibiotic biosynthesis monooxygenase domain-containing protein YP_879842.1 545913 R 243243 CDS YP_879843.1 118465309 4526563 546307..547050 1 NC_008595.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta hydrolase family protein 547050 4526563 MAV_0564 Mycobacterium avium 104 hydrolase, alpha/beta hydrolase family protein YP_879843.1 546307 D 243243 CDS YP_879844.1 118466018 4529904 complement(547033..547944) 1 NC_008595.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; A/G-specific adenine glycosylase 547944 4529904 MAV_0563 Mycobacterium avium 104 A/G-specific adenine glycosylase YP_879844.1 547033 R 243243 CDS YP_879845.1 118464265 4528220 547943..548560 1 NC_008595.1 identified by match to protein family HMM PF00484; carbonic anhydrase 548560 4528220 MAV_0565 Mycobacterium avium 104 carbonic anhydrase YP_879845.1 547943 D 243243 CDS YP_879846.1 118463517 4527697 548672..549505 1 NC_008595.1 hypothetical protein 549505 4527697 MAV_0566 Mycobacterium avium 104 hypothetical protein YP_879846.1 548672 D 243243 CDS YP_879847.1 118466068 4530038 complement(549533..550606) 1 NC_008595.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 550606 4530038 MAV_0567 Mycobacterium avium 104 DNA integrity scanning protein DisA YP_879847.1 549533 R 243243 CDS YP_879848.1 118465491 4526787 complement(550603..551982) 1 NC_008595.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 551982 radA 4526787 radA Mycobacterium avium 104 DNA repair protein RadA YP_879848.1 550603 R 243243 CDS YP_879849.1 118463593 4529779 complement(552077..552643) 1 NC_008595.1 LpqE protein 552643 4529779 MAV_0569 Mycobacterium avium 104 LpqE protein YP_879849.1 552077 R 243243 CDS YP_879850.1 118464023 4528819 552922..553410 1 NC_008595.1 identified by match to protein family HMM PF02559; CarD family transcriptional regulator 553410 4528819 MAV_0570 Mycobacterium avium 104 CarD family transcriptional regulator YP_879850.1 552922 D 243243 CDS YP_879851.1 118464741 4529428 553445..554134 1 NC_008595.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 554134 ispD 4529428 ispD Mycobacterium avium 104 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_879851.1 553445 D 243243 CDS YP_879852.1 118463287 4530535 554131..554610 1 NC_008595.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 554610 ispF 4530535 ispF Mycobacterium avium 104 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_879852.1 554131 D 243243 CDS YP_879853.1 118466391 4526192 554659..556065 1 NC_008595.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 556065 cysS 4526192 cysS Mycobacterium avium 104 cysteinyl-tRNA synthetase YP_879853.1 554659 D 243243 CDS YP_879854.1 118465233 4525604 556066..556995 1 NC_008595.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase, TrmH family protein, group 3 556995 4525604 MAV_0574 Mycobacterium avium 104 RNA methyltransferase, TrmH family protein, group 3 YP_879854.1 556066 D 243243 CDS YP_879855.1 118467098 4526359 556992..557936 1 NC_008595.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 557936 4526359 MAV_0576 Mycobacterium avium 104 glycerophosphoryl diester phosphodiesterase YP_879855.1 556992 D 243243 CDS YP_879856.1 118463637 4528539 complement(557840..559273) 1 NC_008595.1 hypothetical protein 559273 4528539 MAV_0575 Mycobacterium avium 104 hypothetical protein YP_879856.1 557840 R 243243 CDS YP_879857.1 118466786 4529344 559452..562085 1 NC_008595.1 identified by match to protein family HMM PF00196; match to protein family HMM PF07721; LuxR family transcriptional regulator 562085 4529344 MAV_0578 Mycobacterium avium 104 LuxR family transcriptional regulator YP_879857.1 559452 D 243243 CDS YP_879858.1 118466242 4526588 complement(562082..563323) 1 NC_008595.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; arsenical pump membrane protein 563323 4526588 MAV_0577 Mycobacterium avium 104 arsenical pump membrane protein YP_879858.1 562082 R 243243 CDS YP_879859.1 118465624 4528740 complement(563334..564251) 1 NC_008595.1 hypothetical protein 564251 4528740 MAV_0579 Mycobacterium avium 104 hypothetical protein YP_879859.1 563334 R 243243 CDS YP_879860.1 118465070 4527046 complement(564251..565009) 1 NC_008595.1 identified by match to protein family HMM PF03746; LamB/YcsF family protein 565009 4527046 MAV_0580 Mycobacterium avium 104 LamB/YcsF family protein YP_879860.1 564251 R 243243 CDS YP_879861.1 118462479 4530675 complement(565019..565879) 1 NC_008595.1 identified by match to protein family HMM PF00950; match to protein family HMM PF02653; Mn2+/Zn2+ ABC transporter permease 565879 4530675 MAV_0581 Mycobacterium avium 104 Mn2+/Zn2+ ABC transporter permease YP_879861.1 565019 R 243243 CDS YP_879862.1 118463856 4529955 complement(565879..566700) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 566700 4529955 MAV_0582 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_879862.1 565879 R 243243 CDS YP_879863.1 118463328 4529198 complement(566697..567632) 1 NC_008595.1 identified by match to protein family HMM PF01297; periplasmic solute binding protein family protein 567632 4529198 MAV_0583 Mycobacterium avium 104 periplasmic solute binding protein family protein YP_879863.1 566697 R 243243 CDS YP_879864.1 118462693 4526673 567755..568834 1 NC_008595.1 identified by match to protein family HMM PF00532; LacI family transcriptional regulator 568834 4526673 MAV_0585 Mycobacterium avium 104 LacI family transcriptional regulator YP_879864.1 567755 D 243243 CDS YP_879865.1 118465428 4529977 complement(568831..569424) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 569424 4529977 MAV_0584 Mycobacterium avium 104 TetR family transcriptional regulator YP_879865.1 568831 R 243243 CDS YP_879866.1 118465843 4525515 569792..571915 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 571915 4525515 MAV_0587 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879866.1 569792 D 243243 CDS YP_879867.1 118463667 4525959 complement(571912..572484) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 572484 4525959 MAV_0586 Mycobacterium avium 104 TetR family transcriptional regulator YP_879867.1 571912 R 243243 CDS YP_879868.1 118463911 4525842 572569..573450 1 NC_008595.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; oxidoreductase 573450 4525842 MAV_0588 Mycobacterium avium 104 oxidoreductase YP_879868.1 572569 D 243243 CDS YP_879869.1 118467177 4530147 complement(573452..573985) 1 NC_008595.1 hypothetical protein 573985 4530147 MAV_0589 Mycobacterium avium 104 hypothetical protein YP_879869.1 573452 R 243243 CDS YP_879870.1 118465347 4526660 complement(574032..575126) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase, electron transfer component 575126 4526660 MAV_0590 Mycobacterium avium 104 oxidoreductase, electron transfer component YP_879870.1 574032 R 243243 CDS YP_879871.1 118466617 4526855 575339..576523 1 NC_008595.1 identified by match to protein family HMM PF08028; pigment production hydroxylase 576523 4526855 MAV_0591 Mycobacterium avium 104 pigment production hydroxylase YP_879871.1 575339 D 243243 CDS YP_879872.1 118467315 4530308 576520..577401 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 577401 4530308 MAV_0592 Mycobacterium avium 104 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase YP_879872.1 576520 D 243243 CDS YP_879873.1 118462322 4529640 577401..578312 1 NC_008595.1 identified by match to protein family HMM PF00903; extradiol ring-cleavage dioxygenase 578312 4529640 MAV_0593 Mycobacterium avium 104 extradiol ring-cleavage dioxygenase YP_879873.1 577401 D 243243 CDS YP_879874.1 118463043 4528884 578315..578878 1 NC_008595.1 identified by match to protein family HMM PF01613; flavin reductase 578878 4528884 MAV_0594 Mycobacterium avium 104 flavin reductase YP_879874.1 578315 D 243243 CDS YP_879875.1 118465626 4528743 578904..579734 1 NC_008595.1 identified by match to protein family HMM PF00797; arylamine N-acetyltransferase 579734 4528743 MAV_0595 Mycobacterium avium 104 arylamine N-acetyltransferase YP_879875.1 578904 D 243243 CDS YP_879876.1 118465157 4529247 complement(579748..580914) 1 NC_008595.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 580914 4529247 MAV_0596 Mycobacterium avium 104 aspartate aminotransferase YP_879876.1 579748 R 243243 CDS YP_879877.1 118462868 4527096 complement(580911..581870) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 581870 4527096 MAV_0597 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879877.1 580911 R 243243 CDS YP_879878.1 118462358 4527986 complement(581867..582811) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 582811 4527986 MAV_0598 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879878.1 581867 R 243243 CDS YP_879879.1 118467228 4529785 complement(582808..583953) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 583953 4529785 MAV_0599 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879879.1 582808 R 243243 CDS YP_879880.1 118466679 4526629 complement(583953..585482) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 585482 fadD 4526629 fadD Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_879880.1 583953 R 243243 CDS YP_879881.1 118465432 4527301 585542..586690 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 586690 4527301 MAV_0601 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879881.1 585542 D 243243 CDS YP_879882.1 118467079 4526379 586687..587475 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 587475 4526379 MAV_0602 Mycobacterium avium 104 short chain dehydrogenase YP_879882.1 586687 D 243243 CDS YP_879883.1 118464357 4530500 587556..588155 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 588155 4530500 MAV_0603 Mycobacterium avium 104 TetR family transcriptional regulator YP_879883.1 587556 D 243243 CDS YP_879884.1 118463762 4528006 588171..589331 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 589331 4528006 MAV_0604 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_879884.1 588171 D 243243 CDS YP_879885.1 118465968 4528187 complement(589424..590164) 1 NC_008595.1 hypothetical protein 590164 4528187 MAV_0605 Mycobacterium avium 104 hypothetical protein YP_879885.1 589424 R 243243 CDS YP_879886.1 118465004 4526270 complement(590161..590769) 1 NC_008595.1 hypothetical protein 590769 4526270 MAV_0606 Mycobacterium avium 104 hypothetical protein YP_879886.1 590161 R 243243 CDS YP_879887.1 118462918 4526008 complement(590889..591965) 1 NC_008595.1 identified by similarity to GB:AAF98273.1; match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 591965 4526008 MAV_0607 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_879887.1 590889 R 243243 CDS YP_879888.1 118462319 4529637 complement(592012..592755) 1 NC_008595.1 coenzyme A transferase, subunit B 592755 4529637 MAV_0608 Mycobacterium avium 104 coenzyme A transferase, subunit B YP_879888.1 592012 R 243243 CDS YP_879889.1 118464406 4530800 complement(592752..593633) 1 NC_008595.1 identified by match to protein family HMM PF01144; coenzyme A transferase, subunit A 593633 4530800 MAV_0609 Mycobacterium avium 104 coenzyme A transferase, subunit A YP_879889.1 592752 R 243243 CDS YP_879890.1 118463816 4526072 complement(593633..594388) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 594388 4526072 MAV_0610 Mycobacterium avium 104 enoyl-CoA hydratase YP_879890.1 593633 R 243243 CDS YP_879891.1 118465785 4526920 594511..595245 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 595245 4526920 MAV_0611 Mycobacterium avium 104 short chain dehydrogenase YP_879891.1 594511 D 243243 CDS YP_879892.1 118464405 4530799 595260..596165 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 596165 4530799 MAV_0612 Mycobacterium avium 104 short chain dehydrogenase YP_879892.1 595260 D 243243 CDS YP_879893.1 118467215 4529596 complement(596303..596731) 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; AclJ protein 596731 4529596 MAV_0613 Mycobacterium avium 104 AclJ protein YP_879893.1 596303 R 243243 CDS YP_879894.1 118466641 4526997 complement(596754..597155) 1 NC_008595.1 hypothetical protein 597155 4526997 MAV_0614 Mycobacterium avium 104 hypothetical protein YP_879894.1 596754 R 243243 CDS YP_879895.1 118466565 4529114 complement(597174..598334) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 598334 4529114 MAV_0615 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_879895.1 597174 R 243243 CDS YP_879896.1 118463546 4526813 598494..599744 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 124 599744 4526813 MAV_0616 Mycobacterium avium 104 cytochrome P450 124 YP_879896.1 598494 D 243243 CDS YP_879897.1 118465978 4526120 599746..600834 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 600834 4526120 MAV_0617 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879897.1 599746 D 243243 CDS YP_879898.1 118463230 4528804 600825..601988 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 601988 4528804 MAV_0618 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879898.1 600825 D 243243 CDS YP_879899.1 118463131 4529656 601985..602938 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 602938 4529656 MAV_0619 Mycobacterium avium 104 hypothetical protein YP_879899.1 601985 D 243243 CDS YP_879900.1 118465247 4528465 602935..603336 1 NC_008595.1 hypothetical protein 603336 4528465 MAV_0620 Mycobacterium avium 104 hypothetical protein YP_879900.1 602935 D 243243 CDS YP_879901.1 118467263 4526098 603336..604505 1 NC_008595.1 lipid-transfer protein 604505 4526098 MAV_0621 Mycobacterium avium 104 lipid-transfer protein YP_879901.1 603336 D 243243 CDS YP_879902.1 118465527 4530000 604792..605460 1 NC_008595.1 hypothetical protein 605460 4530000 MAV_0622 Mycobacterium avium 104 hypothetical protein YP_879902.1 604792 D 243243 CDS YP_879903.1 118464950 4528212 complement(605543..606403) 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC like domain-containing protein 606403 4528212 MAV_0623 Mycobacterium avium 104 MaoC like domain-containing protein YP_879903.1 605543 R 243243 CDS YP_879904.2 161579551 4527887 complement(606405..608087) 1 NC_008595.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 608087 4527887 MAV_0624 Mycobacterium avium 104 3-ketosteroid-delta-1-dehydrogenase YP_879904.2 606405 R 243243 CDS YP_879905.1 118464113 4526284 608161..608946 1 NC_008595.1 identified by match to protein family HMM PF01689; 2-keto-4-pentenoate hydratase 608946 4526284 MAV_0625 Mycobacterium avium 104 2-keto-4-pentenoate hydratase YP_879905.1 608161 D 243243 CDS YP_879906.2 161579553 4528328 608998..609912 1 NC_008595.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 609912 4528328 MAV_0626 Mycobacterium avium 104 acetaldehyde dehydrogenase YP_879906.2 608998 D 243243 CDS YP_879907.1 118462327 4529645 609909..610967 1 NC_008595.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 610967 4529645 MAV_0627 Mycobacterium avium 104 4-hydroxy-2-ketovalerate aldolase YP_879907.1 609909 D 243243 CDS YP_879908.1 118466722 4530660 611020..611325 1 NC_008595.1 hypothetical protein 611325 4530660 MAV_0628 Mycobacterium avium 104 hypothetical protein YP_879908.1 611020 D 243243 CDS YP_879909.1 118466162 4528785 611415..612542 1 NC_008595.1 hypothetical protein 612542 4528785 MAV_0629 Mycobacterium avium 104 hypothetical protein YP_879909.1 611415 D 243243 CDS YP_879910.1 118465600 4527859 612554..613327 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 613327 4527859 MAV_0630 Mycobacterium avium 104 short chain dehydrogenase YP_879910.1 612554 D 243243 CDS YP_879911.1 118465104 4529995 613324..614469 1 NC_008595.1 hypothetical protein 614469 4529995 MAV_0631 Mycobacterium avium 104 hypothetical protein YP_879911.1 613324 D 243243 CDS YP_879912.1 118464889 4529618 complement(614482..614919) 1 NC_008595.1 hypothetical protein 614919 4529618 MAV_0632 Mycobacterium avium 104 hypothetical protein YP_879912.1 614482 R 243243 CDS YP_879913.1 118462654 4529081 complement(614925..616082) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 616082 4529081 MAV_0633 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_879913.1 614925 R 243243 CDS YP_879914.1 118464692 4527881 616209..616733 1 NC_008595.1 carnitine operon protein CaiE 616733 4527881 MAV_0634 Mycobacterium avium 104 carnitine operon protein CaiE YP_879914.1 616209 D 243243 CDS YP_879915.1 118465410 4525670 complement(616744..617151) 1 NC_008595.1 hypothetical protein 617151 4525670 MAV_0635 Mycobacterium avium 104 hypothetical protein YP_879915.1 616744 R 243243 CDS YP_879916.1 118466748 4526349 complement(617154..618347) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 618347 4526349 MAV_0636 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_879916.1 617154 R 243243 CDS YP_879917.1 118466240 4526586 complement(618347..619411) 1 NC_008595.1 lipid-transfer protein 619411 4526586 MAV_0637 Mycobacterium avium 104 lipid-transfer protein YP_879917.1 618347 R 243243 CDS YP_879918.1 118463428 4528307 complement(619428..620396) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 620396 4528307 MAV_0638 Mycobacterium avium 104 hypothetical protein YP_879918.1 619428 R 243243 CDS YP_879919.1 118466557 4529106 620490..621521 1 NC_008595.1 identified by match to protein family HMM PF00296; FMN-dependent monooxygenase 621521 4529106 MAV_0639 Mycobacterium avium 104 FMN-dependent monooxygenase YP_879919.1 620490 D 243243 CDS YP_879920.1 118462851 4526033 complement(621620..622300) 1 NC_008595.1 hypothetical protein 622300 4526033 MAV_0640 Mycobacterium avium 104 hypothetical protein YP_879920.1 621620 R 243243 CDS YP_879921.1 118463264 4528129 622385..623605 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 623605 4528129 MAV_0641 Mycobacterium avium 104 P450 heme-thiolate protein YP_879921.1 622385 D 243243 CDS YP_879922.1 118463860 4529959 complement(623732..624604) 1 NC_008595.1 hypothetical protein 624604 4529959 MAV_0642 Mycobacterium avium 104 hypothetical protein YP_879922.1 623732 R 243243 CDS YP_879923.1 118464418 4530239 complement(624808..625620) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 625620 4530239 MAV_0643 Mycobacterium avium 104 enoyl-CoA hydratase YP_879923.1 624808 R 243243 CDS YP_879924.1 118466749 4526350 625685..627325 1 NC_008595.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 627325 4526350 MAV_0644 Mycobacterium avium 104 acyl-CoA synthetase YP_879924.1 625685 D 243243 CDS YP_879925.1 118464960 4528700 627335..628102 1 NC_008595.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881; phosphotransferase enzyme family protein, putative 628102 4528700 MAV_0645 Mycobacterium avium 104 phosphotransferase enzyme family protein, putative YP_879925.1 627335 D 243243 CDS YP_879926.1 118462707 4526688 628125..628952 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 628952 4526688 MAV_0646 Mycobacterium avium 104 amidohydrolase YP_879926.1 628125 D 243243 CDS YP_879927.1 118467212 4529593 628949..630499 1 NC_008595.1 thiamine-pyrophosphate requiring enzyme; hypothetical protein 630499 4529593 MAV_0648 Mycobacterium avium 104 hypothetical protein YP_879927.1 628949 D 243243 CDS YP_879928.1 118463510 4527690 complement(630485..631198) 1 NC_008595.1 hypothetical protein 631198 4527690 MAV_0647 Mycobacterium avium 104 hypothetical protein YP_879928.1 630485 R 243243 CDS YP_879929.1 118462646 4529387 complement(631326..631607) 1 NC_008595.1 hypothetical protein 631607 4529387 MAV_0649 Mycobacterium avium 104 hypothetical protein YP_879929.1 631326 R 243243 CDS YP_879930.1 118466777 4529335 complement(631589..633100) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 633100 4529335 MAV_0650 Mycobacterium avium 104 acyl-CoA synthetase YP_879930.1 631589 R 243243 CDS YP_879931.1 118462522 4527665 complement(633106..634203) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 634203 4527665 MAV_0651 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879931.1 633106 R 243243 CDS YP_879932.1 118465700 4530322 complement(634233..635411) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 635411 4530322 MAV_0652 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_879932.1 634233 R 243243 CDS YP_879933.1 118466109 4527738 635625..635816 1 NC_008595.1 hypothetical protein 635816 4527738 MAV_0653 Mycobacterium avium 104 hypothetical protein YP_879933.1 635625 D 243243 CDS YP_879934.1 118465268 4527289 635898..636767 1 NC_008595.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 636767 fabG 4527289 fabG Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_879934.1 635898 D 243243 CDS YP_879935.1 118465663 4526735 637004..637768 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 637768 4526735 MAV_0655 Mycobacterium avium 104 hypothetical protein YP_879935.1 637004 D 243243 CDS YP_879936.1 118463834 4526053 637788..638630 1 NC_008595.1 identified by match to protein family HMM PF02405; ABC transporter transmembrane protein 638630 4526053 MAV_0656 Mycobacterium avium 104 ABC transporter transmembrane protein YP_879936.1 637788 D 243243 CDS YP_879937.1 118464721 4529408 638700..639854 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 639854 4529408 MAV_0657 Mycobacterium avium 104 virulence factor Mce YP_879937.1 638700 D 243243 CDS YP_879938.1 118463448 4529690 639854..640906 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 640906 4529690 MAV_0658 Mycobacterium avium 104 virulence factor Mce YP_879938.1 639854 D 243243 CDS YP_879939.1 118464170 4526480 640896..641960 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 641960 4526480 MAV_0659 Mycobacterium avium 104 virulence factor Mce YP_879939.1 640896 D 243243 CDS YP_879940.1 118462453 4525626 641957..643384 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 643384 4525626 MAV_0660 Mycobacterium avium 104 virulence factor Mce YP_879940.1 641957 D 243243 CDS YP_879941.1 118464340 4529142 643390..644535 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 644535 4529142 MAV_0661 Mycobacterium avium 104 virulence factor Mce YP_879941.1 643390 D 243243 CDS YP_879942.1 118463180 4527703 646286..647017 1 NC_008595.1 hypothetical protein 647017 4527703 MAV_0663 Mycobacterium avium 104 hypothetical protein YP_879942.1 646286 D 243243 CDS YP_879943.1 118466733 4530671 647017..647508 1 NC_008595.1 hypothetical protein 647508 4530671 MAV_0664 Mycobacterium avium 104 hypothetical protein YP_879943.1 647017 D 243243 CDS YP_879944.1 118467277 4527079 complement(647521..648099) 1 NC_008595.1 hypothetical protein 648099 4527079 MAV_0665 Mycobacterium avium 104 hypothetical protein YP_879944.1 647521 R 243243 CDS YP_879945.1 118465720 4527455 complement(648192..649670) 1 NC_008595.1 identified by match to protein family HMM PF00534; match to protein family HMM PF00982; UDP-forming alpha,alpha-trehalose-phosphate synthase 649670 otsA 4527455 otsA Mycobacterium avium 104 UDP-forming alpha,alpha-trehalose-phosphate synthase YP_879945.1 648192 R 243243 CDS YP_879946.1 118465030 4530079 complement(649671..649835) 1 NC_008595.1 hypothetical protein 649835 4530079 MAV_0667 Mycobacterium avium 104 hypothetical protein YP_879946.1 649671 R 243243 CDS YP_879947.1 118463720 4528070 649968..650672 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 650672 pstB 4528070 pstB Mycobacterium avium 104 ABC transporter ATP-binding protein YP_879947.1 649968 D 243243 CDS YP_879948.1 118463042 4528883 650669..651451 1 NC_008595.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 651451 4528883 MAV_0669 Mycobacterium avium 104 hypothetical protein YP_879948.1 650669 D 243243 CDS YP_879949.1 118464926 4528566 651534..652469 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 652469 4528566 MAV_0670 Mycobacterium avium 104 enoyl-CoA hydratase YP_879949.1 651534 D 243243 CDS YP_879950.1 118464186 4529297 652560..653405 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 653405 4529297 MAV_0671 Mycobacterium avium 104 short chain dehydrogenase YP_879950.1 652560 D 243243 CDS YP_879951.1 118466034 4528042 653420..654211 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase 654211 4528042 MAV_0672 Mycobacterium avium 104 oxidoreductase YP_879951.1 653420 D 243243 CDS YP_879952.1 118465330 4526526 complement(654216..655781) 1 NC_008595.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; cell envelope-related function transcriptional attenuator 655781 4526526 MAV_0673 Mycobacterium avium 104 cell envelope-related function transcriptional attenuator YP_879952.1 654216 R 243243 CDS YP_879953.1 118466133 4527899 complement(656090..656332) 1 NC_008595.1 hypothetical protein 656332 4527899 MAV_0674 Mycobacterium avium 104 hypothetical protein YP_879953.1 656090 R 243243 CDS YP_879954.1 118463398 4528025 656510..656686 1 NC_008595.1 hypothetical protein 656686 4528025 MAV_0675 Mycobacterium avium 104 hypothetical protein YP_879954.1 656510 D 243243 CDS YP_879955.1 118462799 4525768 complement(656711..658189) 1 NC_008595.1 identified by match to protein family HMM PF01425; 6-aminohexanoate-cyclic-dimer hydrolase 658189 4525768 MAV_0676 Mycobacterium avium 104 6-aminohexanoate-cyclic-dimer hydrolase YP_879955.1 656711 R 243243 CDS YP_879956.1 118464514 4529434 658269..659138 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 659138 4529434 MAV_0677 Mycobacterium avium 104 alpha/beta hydrolase YP_879956.1 658269 D 243243 CDS YP_879957.1 118463963 4527209 659221..659889 1 NC_008595.1 hypothetical protein 659889 4527209 MAV_0678 Mycobacterium avium 104 hypothetical protein YP_879957.1 659221 D 243243 CDS YP_879958.1 118464142 4528844 660045..660491 1 NC_008595.1 identified by match to protein family HMM PF05481; lipoprotein LpqH 660491 4528844 MAV_0679 Mycobacterium avium 104 lipoprotein LpqH YP_879958.1 660045 D 243243 CDS YP_879959.1 118462295 4525640 660541..661500 1 NC_008595.1 hypothetical protein 661500 4525640 MAV_0680 Mycobacterium avium 104 hypothetical protein YP_879959.1 660541 D 243243 CDS YP_879960.1 118463057 4528337 complement(661507..662448) 1 NC_008595.1 identified by match to protein family HMM PF01464; transglycosylase 662448 4528337 MAV_0681 Mycobacterium avium 104 transglycosylase YP_879960.1 661507 R 243243 CDS YP_879961.1 118466202 4530192 662589..663338 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 663338 4530192 MAV_0682 Mycobacterium avium 104 hypothetical protein YP_879961.1 662589 D 243243 CDS YP_879962.1 118467109 4526371 663446..665344 1 NC_008595.1 hypothetical protein 665344 4526371 MAV_0683 Mycobacterium avium 104 hypothetical protein YP_879962.1 663446 D 243243 CDS YP_879963.1 118465841 4525513 665979..666155 1 NC_008595.1 hypothetical protein 666155 4525513 MAV_0684 Mycobacterium avium 104 hypothetical protein YP_879963.1 665979 D 243243 CDS YP_879964.1 118466507 4525590 666235..666525 1 NC_008595.1 hypothetical protein 666525 4525590 MAV_0685 Mycobacterium avium 104 hypothetical protein YP_879964.1 666235 D 243243 CDS YP_879965.1 118465950 4527946 666932..667069 1 NC_008595.1 hypothetical protein 667069 4527946 MAV_0686 Mycobacterium avium 104 hypothetical protein YP_879965.1 666932 D 243243 CDS YP_879966.1 118463928 4528108 complement(667197..667901) 1 NC_008595.1 hypothetical protein 667901 4528108 MAV_0687 Mycobacterium avium 104 hypothetical protein YP_879966.1 667197 R 243243 CDS YP_879967.1 118463551 4526818 668425..668691 1 NC_008595.1 hypothetical protein 668691 4526818 MAV_0688 Mycobacterium avium 104 hypothetical protein YP_879967.1 668425 D 243243 CDS YP_879968.1 118467244 4529801 668925..669836 1 NC_008595.1 hypothetical protein 669836 4529801 MAV_0689 Mycobacterium avium 104 hypothetical protein YP_879968.1 668925 D 243243 CDS YP_879969.1 118462811 4529031 complement(670093..670209) 1 NC_008595.1 hypothetical protein 670209 4529031 MAV_0690 Mycobacterium avium 104 hypothetical protein YP_879969.1 670093 R 243243 CDS YP_879970.1 118463827 4526045 670441..670653 1 NC_008595.1 hypothetical protein 670653 4526045 MAV_0691 Mycobacterium avium 104 hypothetical protein YP_879970.1 670441 D 243243 CDS YP_879971.1 118465678 4525737 670654..671424 1 NC_008595.1 hypothetical protein 671424 4525737 MAV_0692 Mycobacterium avium 104 hypothetical protein YP_879971.1 670654 D 243243 CDS YP_879972.1 118465172 4528662 671667..671786 1 NC_008595.1 hypothetical protein 671786 4528662 MAV_0693 Mycobacterium avium 104 hypothetical protein YP_879972.1 671667 D 243243 CDS YP_879973.1 118463836 4526055 complement(673526..673723) 1 NC_008595.1 identified by match to protein family HMM PF05930; hypothetical protein 673723 4526055 MAV_0696 Mycobacterium avium 104 hypothetical protein YP_879973.1 673526 R 243243 CDS YP_879974.1 118465631 4528748 674161..674538 1 NC_008595.1 hypothetical protein 674538 4528748 MAV_0697 Mycobacterium avium 104 hypothetical protein YP_879974.1 674161 D 243243 CDS YP_879975.1 118466667 4526617 674613..675725 1 NC_008595.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 675725 4526617 MAV_0698 Mycobacterium avium 104 site-specific recombinase, phage integrase YP_879975.1 674613 D 243243 CDS YP_879976.1 118465267 4527288 complement(675903..676619) 1 NC_008595.1 hypothetical protein 676619 4527288 MAV_0700 Mycobacterium avium 104 hypothetical protein YP_879976.1 675903 R 243243 CDS YP_879977.1 118466812 4529059 676779..677498 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator PhoP 677498 phoP 4529059 phoP Mycobacterium avium 104 DNA-binding response regulator PhoP YP_879977.1 676779 D 243243 CDS YP_879978.1 118464141 4528843 677539..678975 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 678975 4528843 MAV_0703 Mycobacterium avium 104 sensor histidine kinase YP_879978.1 677539 D 243243 CDS YP_879979.1 118465821 4525924 complement(678963..679367) 1 NC_008595.1 identified by match to protein family HMM PF01230; HIT domain-containing protein 679367 4525924 MAV_0702 Mycobacterium avium 104 HIT domain-containing protein YP_879979.1 678963 R 243243 CDS YP_879980.1 118463793 4525874 complement(679402..679824) 1 NC_008595.1 identified by match to protein family HMM PF02136; steroid delta-isomerase 679824 4525874 MAV_0704 Mycobacterium avium 104 steroid delta-isomerase YP_879980.1 679402 R 243243 CDS YP_879981.1 118464404 4530798 complement(679894..681021) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase B 681021 4530798 MAV_0705 Mycobacterium avium 104 alcohol dehydrogenase B YP_879981.1 679894 R 243243 CDS YP_879982.1 118463449 4529691 complement(681234..681782) 1 NC_008595.1 hypothetical protein 681782 4529691 MAV_0706 Mycobacterium avium 104 hypothetical protein YP_879982.1 681234 R 243243 CDS YP_879983.1 118462716 4530090 complement(681786..681995) 1 NC_008595.1 hypothetical protein 681995 4530090 MAV_0707 Mycobacterium avium 104 hypothetical protein YP_879983.1 681786 R 243243 CDS YP_879984.1 118467111 4526373 complement(682008..683363) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 51 683363 4526373 MAV_0708 Mycobacterium avium 104 cytochrome P450 51 YP_879984.1 682008 R 243243 CDS YP_879985.1 118466249 4526868 complement(683360..684187) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 684187 4526868 MAV_0709 Mycobacterium avium 104 short chain dehydrogenase YP_879985.1 683360 R 243243 CDS YP_879986.1 118463659 4525951 complement(685410..686057) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 686057 4525951 MAV_0711 Mycobacterium avium 104 TetR family transcriptional regulator YP_879986.1 685410 R 243243 CDS YP_879987.1 118467100 4526361 complement(686067..686267) 1 NC_008595.1 hypothetical protein 686267 4526361 MAV_0712 Mycobacterium avium 104 hypothetical protein YP_879987.1 686067 R 243243 CDS YP_879988.1 118464134 4528836 686271..687740 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase (NAD) family protein 687740 4528836 MAV_0713 Mycobacterium avium 104 aldehyde dehydrogenase (NAD) family protein YP_879988.1 686271 D 243243 CDS YP_879989.1 118463242 4525778 687771..688520 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 688520 4525778 MAV_0714 Mycobacterium avium 104 short chain dehydrogenase YP_879989.1 687771 D 243243 CDS YP_879990.1 118462661 4529089 688517..689395 1 NC_008595.1 identified by match to protein family HMM PF03446; oxidoreductase 689395 4529089 MAV_0715 Mycobacterium avium 104 oxidoreductase YP_879990.1 688517 D 243243 CDS YP_879991.1 118465343 4526656 689392..689832 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 689832 pcaC 4526656 pcaC Mycobacterium avium 104 hypothetical protein YP_879991.1 689392 D 243243 CDS YP_879992.1 118467191 4528425 689855..691123 1 NC_008595.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 691123 purD 4528425 purD Mycobacterium avium 104 phosphoribosylamine--glycine ligase YP_879992.1 689855 D 243243 CDS YP_879993.1 118467107 4526369 complement(691120..692703) 1 NC_008595.1 identified by match to protein family HMM PF01019; match to protein family HMM TIGR00066; gamma-glutamyltransferase 692703 ggt 4526369 ggt Mycobacterium avium 104 gamma-glutamyltransferase YP_879993.1 691120 R 243243 CDS YP_879994.1 118466543 4527011 complement(692779..693699) 1 NC_008595.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR01409; esterase 693699 4527011 MAV_0719 Mycobacterium avium 104 esterase YP_879994.1 692779 R 243243 CDS YP_879995.1 118464444 4525975 693821..694390 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 694390 4525975 MAV_0721 Mycobacterium avium 104 TetR family transcriptional regulator YP_879995.1 693821 D 243243 CDS YP_879996.1 118462412 4525722 complement(694344..695135) 1 NC_008595.1 hypothetical protein 695135 4525722 MAV_0720 Mycobacterium avium 104 hypothetical protein YP_879996.1 694344 R 243243 CDS YP_879997.1 118465496 4526792 695239..696657 1 NC_008595.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 696657 purB 4526792 purB Mycobacterium avium 104 adenylosuccinate lyase YP_879997.1 695239 D 243243 CDS YP_879998.1 118465417 4529966 696654..697901 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 monooxygenase 697901 4529966 MAV_0723 Mycobacterium avium 104 P450 monooxygenase YP_879998.1 696654 D 243243 CDS YP_879999.1 118467118 4526144 complement(697940..698560) 1 NC_008595.1 hypothetical protein 698560 4526144 MAV_0724 Mycobacterium avium 104 hypothetical protein YP_879999.1 697940 R 243243 CDS YP_880000.1 118466397 4526239 698613..699503 1 NC_008595.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 699503 purC 4526239 purC Mycobacterium avium 104 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_880000.1 698613 D 243243 CDS YP_880001.1 118464543 4530413 699500..701662 1 NC_008595.1 identified by match to protein family HMM PF00326; match to protein family HMM PF02897; protease 2 701662 4530413 MAV_0727 Mycobacterium avium 104 protease 2 YP_880001.1 699500 D 243243 CDS YP_880002.1 118464636 4528971 complement(701591..702067) 1 NC_008595.1 hypothetical protein 702067 4528971 MAV_0726 Mycobacterium avium 104 hypothetical protein YP_880002.1 701591 R 243243 CDS YP_880003.1 118462849 4526031 702134..702697 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 702697 4526031 MAV_0728 Mycobacterium avium 104 TetR family transcriptional regulator YP_880003.1 702134 D 243243 CDS YP_880004.1 118465955 4527951 complement(702703..704316) 1 NC_008595.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; EmrB efflux protein 704316 4527951 MAV_0729 Mycobacterium avium 104 EmrB efflux protein YP_880004.1 702703 R 243243 CDS YP_880005.1 118463591 4529776 complement(704436..706118) 1 NC_008595.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; EmrB efflux protein 706118 4529776 MAV_0730 Mycobacterium avium 104 EmrB efflux protein YP_880005.1 704436 R 243243 CDS YP_880006.1 118466994 4529521 706192..706884 1 NC_008595.1 hypothetical protein 706884 4529521 MAV_0731 Mycobacterium avium 104 hypothetical protein YP_880006.1 706192 D 243243 CDS YP_880007.1 118465066 4527042 706933..708600 1 NC_008595.1 proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 708600 4527042 MAV_0732 Mycobacterium avium 104 FAD-binding dehydrogenase YP_880007.1 706933 D 243243 CDS YP_880008.1 118462659 4529087 complement(708612..709250) 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase, putative 709250 4529087 MAV_0733 Mycobacterium avium 104 metallo-beta-lactamase, putative YP_880008.1 708612 R 243243 CDS YP_880009.1 118464114 4526285 709269..709961 1 NC_008595.1 hypothetical protein 709961 4526285 MAV_0734 Mycobacterium avium 104 hypothetical protein YP_880009.1 709269 D 243243 CDS YP_880010.1 118464701 4527890 710024..710263 1 NC_008595.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 710263 purS 4527890 purS Mycobacterium avium 104 phosphoribosylformylglycinamidine synthase subunit PurS YP_880010.1 710024 D 243243 CDS YP_880011.1 118466146 4527912 710260..710934 1 NC_008595.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 710934 purQ 4527912 purQ Mycobacterium avium 104 phosphoribosylformylglycinamidine synthase I YP_880011.1 710260 D 243243 CDS YP_880012.1 118463138 4529663 complement(710946..711452) 1 NC_008595.1 hypothetical protein 711452 4529663 MAV_0737 Mycobacterium avium 104 hypothetical protein YP_880012.1 710946 R 243243 CDS YP_880013.1 118463819 4526075 complement(711492..712313) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; mercuric reductase/transcriptional regulator, fusion 712313 4526075 MAV_0738 Mycobacterium avium 104 mercuric reductase/transcriptional regulator, fusion YP_880013.1 711492 R 243243 CDS YP_880014.1 118465528 4530001 complement(712435..712902) 1 NC_008595.1 identified by match to protein family HMM PF07883; cupin domain-containing protein 712902 4530001 MAV_0739 Mycobacterium avium 104 cupin domain-containing protein YP_880014.1 712435 R 243243 CDS YP_880015.1 118462374 4529187 complement(712909..713706) 1 NC_008595.1 identified by match to protein family HMM PF04454; 29 kDa antigen Cfp29 713706 4529187 MAV_0740 Mycobacterium avium 104 29 kDa antigen Cfp29 YP_880015.1 712909 R 243243 CDS YP_880016.1 118464075 4528388 complement(713703..714713) 1 NC_008595.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413; Dyp-type peroxidase 714713 4528388 MAV_0741 Mycobacterium avium 104 Dyp-type peroxidase YP_880016.1 713703 R 243243 CDS YP_880017.1 118463182 4527705 714757..716064 1 NC_008595.1 catalyzes the removal of amino acids from the N termini of peptides; aminopeptidase 716064 4527705 MAV_0742 Mycobacterium avium 104 aminopeptidase YP_880017.1 714757 D 243243 CDS YP_880018.1 118462624 4526426 716084..716431 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 716431 4526426 MAV_0743 Mycobacterium avium 104 glyoxalase YP_880018.1 716084 D 243243 CDS YP_880019.1 118466281 4527834 716782..719079 1 NC_008595.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 719079 purL 4527834 purL Mycobacterium avium 104 phosphoribosylformylglycinamidine synthase II YP_880019.1 716782 D 243243 CDS YP_880020.1 118462318 4529636 719099..719749 1 NC_008595.1 identified by match to protein family HMM PF02517; caax amino protease 719749 4529636 MAV_0745 Mycobacterium avium 104 caax amino protease YP_880020.1 719099 D 243243 CDS YP_880021.1 118463122 4529647 719762..720151 1 NC_008595.1 hypothetical protein 720151 4529647 MAV_0746 Mycobacterium avium 104 hypothetical protein YP_880021.1 719762 D 243243 CDS YP_880022.1 118464802 4526726 720289..721815 1 NC_008595.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 721815 purF 4526726 purF Mycobacterium avium 104 amidophosphoribosyltransferase YP_880022.1 720289 D 243243 CDS YP_880023.1 118464238 4528611 721876..722970 1 NC_008595.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 722970 purM 4528611 purM Mycobacterium avium 104 phosphoribosylaminoimidazole synthetase YP_880023.1 721876 D 243243 CDS YP_880024.1 118466957 4530269 complement(723050..723235) 1 NC_008595.1 hypothetical protein 723235 4530269 MAV_0749 Mycobacterium avium 104 hypothetical protein YP_880024.1 723050 R 243243 CDS YP_880025.1 118466255 4526874 complement(723382..724476) 1 NC_008595.1 identified by match to protein family HMM PF01571; glycine cleavage T-protein (aminomethyl transferase) 724476 4526874 MAV_0750 Mycobacterium avium 104 glycine cleavage T-protein (aminomethyl transferase) YP_880025.1 723382 R 243243 CDS YP_880026.1 118463298 4525993 724587..725456 1 NC_008595.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 725456 4525993 MAV_0751 Mycobacterium avium 104 4-amino-4-deoxychorismate lyase YP_880026.1 724587 D 243243 CDS YP_880027.1 118462591 4530212 complement(725568..726605) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 726605 4530212 MAV_0752 Mycobacterium avium 104 transposase YP_880027.1 725568 R 243243 CDS YP_880028.1 118462776 4527273 complement(726825..727433) 1 NC_008595.1 hypothetical protein 727433 4527273 MAV_0753 Mycobacterium avium 104 hypothetical protein YP_880028.1 726825 R 243243 CDS YP_880029.1 118464591 4530102 complement(727478..727576) 1 NC_008595.1 hypothetical protein 727576 4530102 MAV_0754 Mycobacterium avium 104 hypothetical protein YP_880029.1 727478 R 243243 CDS YP_880030.1 118465007 4526273 complement(727756..728034) 1 NC_008595.1 identified by match to protein family HMM PF07210; SseC protein 728034 4526273 MAV_0755 Mycobacterium avium 104 SseC protein YP_880030.1 727756 R 243243 CDS YP_880031.1 118466798 4529044 complement(728060..728893) 1 NC_008595.1 identified by match to protein family HMM PF00581; thiosulfate sulfurtransferase 728893 4529044 MAV_0756 Mycobacterium avium 104 thiosulfate sulfurtransferase YP_880031.1 728060 R 243243 CDS YP_880032.1 118467134 4527147 complement(728930..729400) 1 NC_008595.1 integral membrane protein 729400 4527147 MAV_0757 Mycobacterium avium 104 integral membrane protein YP_880032.1 728930 R 243243 CDS YP_880033.1 118462455 4525628 complement(729623..730042) 1 NC_008595.1 identified by match to protein family HMM PF00085; thioredoxin 730042 4525628 MAV_0758 Mycobacterium avium 104 thioredoxin YP_880033.1 729623 R 243243 CDS YP_880034.1 118464675 4528370 complement(730039..730851) 1 NC_008595.1 hypothetical protein 730851 4528370 MAV_0759 Mycobacterium avium 104 hypothetical protein YP_880034.1 730039 R 243243 CDS YP_880035.1 118465464 4526232 731020..731802 1 NC_008595.1 identified by match to protein family HMM PF00486; transcriptional regulator 731802 4526232 MAV_0760 Mycobacterium avium 104 transcriptional regulator YP_880035.1 731020 D 243243 CDS YP_880036.1 118464958 4528698 731799..732749 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, GNAT family protein 732749 4528698 MAV_0761 Mycobacterium avium 104 acetyltransferase, GNAT family protein YP_880036.1 731799 D 243243 CDS YP_880037.1 118462403 4525713 complement(732786..732899) 1 NC_008595.1 hypothetical protein 732899 4525713 MAV_0762 Mycobacterium avium 104 hypothetical protein YP_880037.1 732786 R 243243 CDS YP_880038.1 118466799 4529045 complement(733973..734086) 1 NC_008595.1 hypothetical protein 734086 4529045 MAV_0763 Mycobacterium avium 104 hypothetical protein YP_880038.1 733973 R 243243 CDS YP_880039.1 118467220 4529601 735129..736043 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 736043 pstA 4529601 pstA Mycobacterium avium 104 phosphate ABC transporter permease YP_880039.1 735129 D 243243 CDS YP_880040.1 118462957 4526325 736056..736832 1 NC_008595.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 736832 pstB 4526325 pstB Mycobacterium avium 104 phosphate transporter ATP-binding protein YP_880040.1 736056 D 243243 CDS YP_880041.1 118462892 4527499 complement(737019..737687) 1 NC_008595.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 737687 phoU 4527499 phoU Mycobacterium avium 104 phosphate transport system regulatory protein PhoU YP_880041.1 737019 R 243243 CDS YP_880042.1 118463613 4527560 complement(737746..739734) 1 NC_008595.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; LytR/CpsA/Psr family protein 739734 4527560 MAV_0769 Mycobacterium avium 104 LytR/CpsA/Psr family protein YP_880042.1 737746 R 243243 CDS YP_880043.1 118464261 4528216 739792..740055 1 NC_008595.1 hypothetical protein 740055 4528216 MAV_0770 Mycobacterium avium 104 hypothetical protein YP_880043.1 739792 D 243243 CDS YP_880044.1 118466583 4527373 complement(740057..741190) 1 NC_008595.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737; dihydrouridine synthase 741190 4527373 MAV_0771 Mycobacterium avium 104 dihydrouridine synthase YP_880044.1 740057 R 243243 CDS YP_880045.1 118466049 4528057 complement(741197..742219) 1 NC_008595.1 identified by match to protein family HMM PF03405; fatty acid desaturase 742219 4528057 MAV_0772 Mycobacterium avium 104 fatty acid desaturase YP_880045.1 741197 R 243243 CDS YP_880046.1 118463319 4529559 complement(742404..742982) 1 NC_008595.1 hypothetical protein 742982 4529559 MAV_0773 Mycobacterium avium 104 hypothetical protein YP_880046.1 742404 R 243243 CDS YP_880047.1 118462424 4528287 743087..744160 1 NC_008595.1 hypothetical protein 744160 4528287 MAV_0774 Mycobacterium avium 104 hypothetical protein YP_880047.1 743087 D 243243 CDS YP_880048.1 118464477 4528851 complement(744177..744380) 1 NC_008595.1 zinc transporter 744380 4528851 MAV_0775 Mycobacterium avium 104 zinc transporter YP_880048.1 744177 R 243243 CDS YP_880049.1 118463740 4528148 complement(744436..744768) 1 NC_008595.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 744768 4528148 MAV_0776 Mycobacterium avium 104 ArsR family transcriptional regulator YP_880049.1 744436 R 243243 CDS YP_880050.1 118463808 4526063 complement(744881..745381) 1 NC_008595.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase 745381 4526063 MAV_0777 Mycobacterium avium 104 cytidine/deoxycytidylate deaminase YP_880050.1 744881 R 243243 CDS YP_880051.1 118462912 4528175 745460..746356 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 746356 4528175 MAV_0778 Mycobacterium avium 104 methyltransferase, putative, family protein YP_880051.1 745460 D 243243 CDS YP_880052.1 118465318 4526514 746939..747421 1 NC_008595.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 747421 4526514 MAV_0779 Mycobacterium avium 104 site-specific recombinase, phage integrase YP_880052.1 746939 D 243243 CDS YP_880053.1 118464290 4529578 747462..747791 1 NC_008595.1 hypothetical protein 747791 4529578 MAV_0780 Mycobacterium avium 104 hypothetical protein YP_880053.1 747462 D 243243 CDS YP_880054.1 118466025 4529911 747788..748441 1 NC_008595.1 hypothetical protein 748441 4529911 MAV_0781 Mycobacterium avium 104 hypothetical protein YP_880054.1 747788 D 243243 CDS YP_880055.1 118465327 4526523 complement(748452..748553) 1 NC_008595.1 hypothetical protein 748553 4526523 MAV_0782 Mycobacterium avium 104 hypothetical protein YP_880055.1 748452 R 243243 CDS YP_880056.1 118467161 4527592 complement(748550..749020) 1 NC_008595.1 hypothetical protein 749020 4527592 MAV_0783 Mycobacterium avium 104 hypothetical protein YP_880056.1 748550 R 243243 CDS YP_880057.1 118466433 4530177 complement(749056..749328) 1 NC_008595.1 hypothetical protein 749328 4530177 MAV_0784 Mycobacterium avium 104 hypothetical protein YP_880057.1 749056 R 243243 CDS YP_880058.1 118462447 4525620 complement(749399..749569) 1 NC_008595.1 hypothetical protein 749569 4525620 MAV_0785 Mycobacterium avium 104 hypothetical protein YP_880058.1 749399 R 243243 CDS YP_880059.1 118463115 4527177 complement(749633..750574) 1 NC_008595.1 gp53 protein 750574 4527177 MAV_0786 Mycobacterium avium 104 gp53 protein YP_880059.1 749633 R 243243 CDS YP_880060.1 118463513 4527693 complement(750571..751947) 1 NC_008595.1 identified by match to protein family HMM PF01183; gp50 protein 751947 4527693 MAV_0787 Mycobacterium avium 104 gp50 protein YP_880060.1 750571 R 243243 CDS YP_880061.1 118464249 4527434 complement(751944..752360) 1 NC_008595.1 hypothetical protein 752360 4527434 MAV_0788 Mycobacterium avium 104 hypothetical protein YP_880061.1 751944 R 243243 CDS YP_880062.1 118466406 4526249 complement(752341..753216) 1 NC_008595.1 hypothetical protein 753216 4526249 MAV_0789 Mycobacterium avium 104 hypothetical protein YP_880062.1 752341 R 243243 CDS YP_880063.1 118467068 4526446 complement(753228..754160) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 754160 4526446 MAV_0790 Mycobacterium avium 104 PPE family protein YP_880063.1 753228 R 243243 CDS YP_880064.1 118462434 4528297 complement(754309..756006) 1 NC_008595.1 hypothetical protein 756006 4528297 MAV_0791 Mycobacterium avium 104 hypothetical protein YP_880064.1 754309 R 243243 CDS YP_880065.1 118463031 4528872 complement(756008..756397) 1 NC_008595.1 gp34 protein 756397 4528872 MAV_0792 Mycobacterium avium 104 gp34 protein YP_880065.1 756008 R 243243 CDS YP_880066.1 118464161 4526471 complement(756408..756839) 1 NC_008595.1 gp27 protein 756839 4526471 MAV_0793 Mycobacterium avium 104 gp27 protein YP_880066.1 756408 R 243243 CDS YP_880067.1 118466526 4527199 complement(756886..758385) 1 NC_008595.1 gp28 protein 758385 4527199 MAV_0794 Mycobacterium avium 104 gp28 protein YP_880067.1 756886 R 243243 CDS YP_880068.1 118465994 4526136 complement(758533..758844) 1 NC_008595.1 hypothetical protein 758844 4526136 MAV_0795 Mycobacterium avium 104 hypothetical protein YP_880068.1 758533 R 243243 CDS YP_880069.1 118463648 4528550 complement(758848..760443) 1 NC_008595.1 hypothetical protein 760443 4528550 MAV_0796 Mycobacterium avium 104 hypothetical protein YP_880069.1 758848 R 243243 CDS YP_880070.1 118464218 4526898 complement(760440..761345) 1 NC_008595.1 gp37 protein 761345 4526898 MAV_0797 Mycobacterium avium 104 gp37 protein YP_880070.1 760440 R 243243 CDS YP_880071.1 118462502 4528580 complement(761342..763078) 1 NC_008595.1 gp36 protein 763078 4528580 MAV_0798 Mycobacterium avium 104 gp36 protein YP_880071.1 761342 R 243243 CDS YP_880072.1 118463059 4528339 complement(763075..764559) 1 NC_008595.1 gp23 protein 764559 4528339 MAV_0799 Mycobacterium avium 104 gp23 protein YP_880072.1 763075 R 243243 CDS YP_880073.1 118465027 4530076 complement(764576..769555) 1 NC_008595.1 identified by match to protein family HMM TIGR01760; phage tail tape measure protein, family protein, core region 769555 4530076 MAV_0800 Mycobacterium avium 104 phage tail tape measure protein, family protein, core region YP_880073.1 764576 R 243243 CDS YP_880074.1 118466827 4527392 complement(769607..770008) 1 NC_008595.1 hypothetical protein 770008 4527392 MAV_0801 Mycobacterium avium 104 hypothetical protein YP_880074.1 769607 R 243243 CDS YP_880075.1 118466130 4527896 complement(770061..770546) 1 NC_008595.1 gp32 protein 770546 4527896 MAV_0802 Mycobacterium avium 104 gp32 protein YP_880075.1 770061 R 243243 CDS YP_880076.1 118463498 4529077 complement(770634..771680) 1 NC_008595.1 gp31 protein 771680 4529077 MAV_0803 Mycobacterium avium 104 gp31 protein YP_880076.1 770634 R 243243 CDS YP_880077.1 118462744 4527815 complement(771753..772175) 1 NC_008595.1 hypothetical protein 772175 4527815 MAV_0804 Mycobacterium avium 104 hypothetical protein YP_880077.1 771753 R 243243 CDS YP_880078.1 118464990 4527482 complement(772172..772693) 1 NC_008595.1 hypothetical protein 772693 4527482 MAV_0805 Mycobacterium avium 104 hypothetical protein YP_880078.1 772172 R 243243 CDS YP_880079.1 118464639 4528974 complement(772788..773225) 1 NC_008595.1 hypothetical protein 773225 4528974 MAV_0806 Mycobacterium avium 104 hypothetical protein YP_880079.1 772788 R 243243 CDS YP_880080.1 118465706 4530328 complement(773218..773700) 1 NC_008595.1 hypothetical protein 773700 4530328 MAV_0807 Mycobacterium avium 104 hypothetical protein YP_880080.1 773218 R 243243 CDS YP_880081.1 118465038 4525817 complement(773702..774034) 1 NC_008595.1 hypothetical protein 774034 4525817 MAV_0808 Mycobacterium avium 104 hypothetical protein YP_880081.1 773702 R 243243 CDS YP_880082.1 118466856 4529808 complement(774034..775071) 1 NC_008595.1 hypothetical protein 775071 4529808 MAV_0809 Mycobacterium avium 104 hypothetical protein YP_880082.1 774034 R 243243 CDS YP_880083.1 118466605 4529371 complement(775180..775578) 1 NC_008595.1 hypothetical protein 775578 4529371 MAV_0810 Mycobacterium avium 104 hypothetical protein YP_880083.1 775180 R 243243 CDS YP_880084.1 118466246 4526865 complement(775580..776845) 1 NC_008595.1 hypothetical protein 776845 4526865 MAV_0811 Mycobacterium avium 104 hypothetical protein YP_880084.1 775580 R 243243 CDS YP_880085.1 118463246 4525782 complement(776851..778272) 1 NC_008595.1 hypothetical protein 778272 4525782 MAV_0812 Mycobacterium avium 104 hypothetical protein YP_880085.1 776851 R 243243 CDS YP_880086.1 118462814 4529034 complement(778410..779867) 1 NC_008595.1 identified by match to protein family HMM PF03354; phage terminase, large subunit, putative 779867 4529034 MAV_0813 Mycobacterium avium 104 phage terminase, large subunit, putative YP_880086.1 778410 R 243243 CDS YP_880087.1 118464248 4527433 complement(779911..780270) 1 NC_008595.1 hypothetical protein 780270 4527433 MAV_0814 Mycobacterium avium 104 hypothetical protein YP_880087.1 779911 R 243243 CDS YP_880088.1 118464224 4528597 complement(780481..780702) 1 NC_008595.1 hypothetical protein 780702 4528597 MAV_0815 Mycobacterium avium 104 hypothetical protein YP_880088.1 780481 R 243243 CDS YP_880089.1 118464683 4528378 complement(780831..781064) 1 NC_008595.1 hypothetical protein 781064 4528378 MAV_0816 Mycobacterium avium 104 hypothetical protein YP_880089.1 780831 R 243243 CDS YP_880090.1 118464318 4526649 complement(781061..781471) 1 NC_008595.1 hypothetical protein 781471 4526649 MAV_0817 Mycobacterium avium 104 hypothetical protein YP_880090.1 781061 R 243243 CDS YP_880091.1 118463575 4530730 complement(781461..781871) 1 NC_008595.1 hypothetical protein 781871 4530730 MAV_0818 Mycobacterium avium 104 hypothetical protein YP_880091.1 781461 R 243243 CDS YP_880092.1 118465690 4525749 complement(782071..782667) 1 NC_008595.1 gp75 protein 782667 4525749 MAV_0819 Mycobacterium avium 104 gp75 protein YP_880092.1 782071 R 243243 CDS YP_880093.1 118464973 4528713 complement(782667..783032) 1 NC_008595.1 hypothetical protein 783032 4528713 MAV_0820 Mycobacterium avium 104 hypothetical protein YP_880093.1 782667 R 243243 CDS YP_880094.1 118467213 4529594 complement(783111..783476) 1 NC_008595.1 hypothetical protein 783476 4529594 MAV_0821 Mycobacterium avium 104 hypothetical protein YP_880094.1 783111 R 243243 CDS YP_880095.1 118466673 4526623 complement(783608..783976) 1 NC_008595.1 gp79 protein 783976 4526623 MAV_0822 Mycobacterium avium 104 gp79 protein YP_880095.1 783608 R 243243 CDS YP_880096.1 118465967 4528186 complement(783973..784884) 1 NC_008595.1 gp78 protein 784884 4528186 MAV_0823 Mycobacterium avium 104 gp78 protein YP_880096.1 783973 R 243243 CDS YP_880097.1 118463610 4527557 complement(784884..785099) 1 NC_008595.1 hypothetical protein 785099 4527557 MAV_0824 Mycobacterium avium 104 hypothetical protein YP_880097.1 784884 R 243243 CDS YP_880098.1 118462989 4530619 complement(785156..785281) 1 NC_008595.1 hypothetical protein 785281 4530619 MAV_0825 Mycobacterium avium 104 hypothetical protein YP_880098.1 785156 R 243243 CDS YP_880099.1 118462283 4529288 complement(785453..785734) 1 NC_008595.1 hypothetical protein 785734 4529288 MAV_0826 Mycobacterium avium 104 hypothetical protein YP_880099.1 785453 R 243243 CDS YP_880100.1 118463891 4530568 complement(785833..786243) 1 NC_008595.1 hypothetical protein 786243 4530568 MAV_0827 Mycobacterium avium 104 hypothetical protein YP_880100.1 785833 R 243243 CDS YP_880101.1 118463538 4526844 complement(786286..787950) 1 NC_008595.1 similar to Rickettsia 17 kDa surface antigen family protein; 17 kDa surface antigen family protein 787950 4526844 MAV_0828 Mycobacterium avium 104 17 kDa surface antigen family protein YP_880101.1 786286 R 243243 CDS YP_880102.1 118462457 4525630 complement(788198..789310) 1 NC_008595.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR00616; recombination and repair protein RecT 789310 recT 4525630 recT Mycobacterium avium 104 recombination and repair protein RecT YP_880102.1 788198 R 243243 CDS YP_880103.1 118463052 4528331 complement(789326..790180) 1 NC_008595.1 gp60 protein 790180 4528331 MAV_0830 Mycobacterium avium 104 gp60 protein YP_880103.1 789326 R 243243 CDS YP_880104.1 118467217 4529598 complement(790173..790301) 1 NC_008595.1 hypothetical protein 790301 4529598 MAV_0831 Mycobacterium avium 104 hypothetical protein YP_880104.1 790173 R 243243 CDS YP_880105.1 118466538 4527006 complement(790298..790558) 1 NC_008595.1 hypothetical protein 790558 4527006 MAV_0832 Mycobacterium avium 104 hypothetical protein YP_880105.1 790298 R 243243 CDS YP_880106.1 118467086 4526386 790604..790762 1 NC_008595.1 hypothetical protein 790762 4526386 MAV_0833 Mycobacterium avium 104 hypothetical protein YP_880106.1 790604 D 243243 CDS YP_880107.1 118463976 4530334 complement(790940..791188) 1 NC_008595.1 hypothetical protein 791188 4530334 MAV_0834 Mycobacterium avium 104 hypothetical protein YP_880107.1 790940 R 243243 CDS YP_880108.1 118464578 4530282 complement(791318..791605) 1 NC_008595.1 hypothetical protein 791605 4530282 MAV_0835 Mycobacterium avium 104 hypothetical protein YP_880108.1 791318 R 243243 CDS YP_880109.1 118466220 4528900 complement(791602..791754) 1 NC_008595.1 hypothetical protein 791754 4528900 MAV_0836 Mycobacterium avium 104 hypothetical protein YP_880109.1 791602 R 243243 CDS YP_880110.1 118466591 4529357 complement(791751..792539) 1 NC_008595.1 identified by match to protein family HMM PF02498; gp54 protein 792539 4529357 MAV_0837 Mycobacterium avium 104 gp54 protein YP_880110.1 791751 R 243243 CDS YP_880111.1 118465041 4525820 complement(792536..792646) 1 NC_008595.1 hypothetical protein 792646 4525820 MAV_0838 Mycobacterium avium 104 hypothetical protein YP_880111.1 792536 R 243243 CDS YP_880112.1 118465500 4526796 complement(792643..793434) 1 NC_008595.1 identified by match to protein family HMM PF02498; gp54 protein 793434 4526796 MAV_0839 Mycobacterium avium 104 gp54 protein YP_880112.1 792643 R 243243 CDS YP_880113.1 118464033 4529005 793512..793724 1 NC_008595.1 hypothetical protein 793724 4529005 MAV_0840 Mycobacterium avium 104 hypothetical protein YP_880113.1 793512 D 243243 CDS YP_880114.1 118464765 4529119 complement(793769..794035) 1 NC_008595.1 identified by match to protein family HMM PF00376; match to protein family HMM TIGR01764; excisionase DNA binding protein 794035 4529119 MAV_0841 Mycobacterium avium 104 excisionase DNA binding protein YP_880114.1 793769 R 243243 CDS YP_880115.1 118463161 4529862 complement(794921..795760) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 795760 4529862 MAV_0846 Mycobacterium avium 104 carveol dehydrogenase YP_880115.1 794921 R 243243 CDS YP_880116.1 118463215 4527542 complement(795891..796445) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 796445 4527542 MAV_0847 Mycobacterium avium 104 TetR family transcriptional regulator YP_880116.1 795891 R 243243 CDS YP_880117.1 118465780 4526915 796608..796826 1 NC_008595.1 hypothetical protein 796826 4526915 MAV_0848 Mycobacterium avium 104 hypothetical protein YP_880117.1 796608 D 243243 CDS YP_880118.1 118466208 4528887 796831..798111 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome p450 798111 4528887 MAV_0849 Mycobacterium avium 104 cytochrome p450 YP_880118.1 796831 D 243243 CDS YP_880119.1 118466744 4526345 798264..798497 1 NC_008595.1 hypothetical protein 798497 4526345 MAV_0850 Mycobacterium avium 104 hypothetical protein YP_880119.1 798264 D 243243 CDS YP_880120.1 118465313 4526567 complement(798519..798656) 1 NC_008595.1 hypothetical protein 798656 4526567 MAV_0851 Mycobacterium avium 104 hypothetical protein YP_880120.1 798519 R 243243 CDS YP_880121.1 118467308 4530300 798980..799183 1 NC_008595.1 identified by match to protein family HMM PF00313; hypothetical protein 799183 4530300 MAV_0852 Mycobacterium avium 104 hypothetical protein YP_880121.1 798980 D 243243 CDS YP_880122.1 118465308 4526562 799324..800022 1 NC_008595.1 identified by match to protein family HMM PF01427; D-alanyl-D-alanine dipeptidase 800022 ddpX 4526562 ddpX Mycobacterium avium 104 D-alanyl-D-alanine dipeptidase YP_880122.1 799324 D 243243 CDS YP_880123.1 118463265 4528130 800111..800923 1 NC_008595.1 identified by match to protein family HMM PF01209; match to protein family HMM PF05175; methyltransferase-UbiE family protein 800923 4528130 MAV_0854 Mycobacterium avium 104 methyltransferase-UbiE family protein YP_880123.1 800111 D 243243 CDS YP_880124.1 118466364 4529926 complement(800928..801752) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 801752 4529926 MAV_0855 Mycobacterium avium 104 short chain dehydrogenase YP_880124.1 800928 R 243243 CDS YP_880125.1 118466674 4526624 801844..803421 1 NC_008595.1 identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641; methylmalonyl-CoA mutase, N-terminus of large subunit 803421 4526624 MAV_0856 Mycobacterium avium 104 methylmalonyl-CoA mutase, N-terminus of large subunit YP_880125.1 801844 D 243243 CDS YP_880126.1 118466131 4527897 803421..803861 1 NC_008595.1 identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640; methylmalonyl-CoA mutase 803861 4527897 MAV_0857 Mycobacterium avium 104 methylmalonyl-CoA mutase YP_880126.1 803421 D 243243 CDS YP_880127.1 118464901 4530736 804798..805838 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 805838 4530736 MAV_0859 Mycobacterium avium 104 caib/baif family protein YP_880127.1 804798 D 243243 CDS YP_880128.1 118464647 4528982 complement(805948..807213) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 807213 4528982 MAV_0860 Mycobacterium avium 104 amidohydrolase YP_880128.1 805948 R 243243 CDS YP_880129.1 118465190 4530387 complement(807217..807531) 1 NC_008595.1 hypothetical protein 807531 4530387 MAV_0861 Mycobacterium avium 104 hypothetical protein YP_880129.1 807217 R 243243 CDS YP_880130.1 118463889 4530566 complement(807549..807887) 1 NC_008595.1 identified by match to protein family HMM PF00111; FdxB protein 807887 4530566 MAV_0862 Mycobacterium avium 104 FdxB protein YP_880130.1 807549 R 243243 CDS YP_880131.1 118466357 4530497 808012..809415 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-binding enzyme 809415 4530497 MAV_0863 Mycobacterium avium 104 AMP-binding enzyme YP_880131.1 808012 D 243243 CDS YP_880132.1 118465760 4530453 809393..810298 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 810298 4530453 MAV_0864 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880132.1 809393 D 243243 CDS YP_880133.1 118462277 4529282 810285..811367 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase middle domain-containing protein 811367 4529282 MAV_0865 Mycobacterium avium 104 acyl-CoA dehydrogenase middle domain-containing protein YP_880133.1 810285 D 243243 CDS YP_880134.1 118463322 4529562 811370..811534 1 NC_008595.1 hypothetical protein 811534 4529562 MAV_0866 Mycobacterium avium 104 hypothetical protein YP_880134.1 811370 D 243243 CDS YP_880135.1 118462698 4526678 811546..812310 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 812310 4526678 MAV_0867 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880135.1 811546 D 243243 CDS YP_880136.1 118464592 4530103 complement(812316..813167) 1 NC_008595.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR01250; proline imino-peptidase 813167 4530103 MAV_0868 Mycobacterium avium 104 proline imino-peptidase YP_880136.1 812316 R 243243 CDS YP_880137.1 118463980 4530338 813293..813811 1 NC_008595.1 identified by match to protein family HMM PF05870; phenolic acid decarboxylase 813811 4530338 MAV_0869 Mycobacterium avium 104 phenolic acid decarboxylase YP_880137.1 813293 D 243243 CDS YP_880138.1 118465597 4527856 815079..815966 1 NC_008595.1 identified by match to protein family HMM PF03308; match to protein family HMM TIGR00750; LAO/AO transport system ATPase 815966 4527856 MAV_0871 Mycobacterium avium 104 LAO/AO transport system ATPase YP_880138.1 815079 D 243243 CDS YP_880139.1 118462818 4529038 816100..816993 1 NC_008595.1 identified by match to protein family HMM PF00676; dehydrogenase E1 component superfamily protein 816993 4529038 MAV_0873 Mycobacterium avium 104 dehydrogenase E1 component superfamily protein YP_880139.1 816100 D 243243 CDS YP_880140.1 118464868 4530704 complement(816986..817537) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 817537 4530704 MAV_0872 Mycobacterium avium 104 LuxR family transcriptional regulator YP_880140.1 816986 R 243243 CDS YP_880141.1 118467032 4526545 817755..818975 1 NC_008595.1 identified by match to protein family HMM PF02518; hypothetical protein 818975 4526545 MAV_0874 Mycobacterium avium 104 hypothetical protein YP_880141.1 817755 D 243243 CDS YP_880142.1 118464073 4528386 complement(819232..820848) 1 NC_008595.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; FAD binding domain-containing protein 820848 4528386 MAV_0875 Mycobacterium avium 104 FAD binding domain-containing protein YP_880142.1 819232 R 243243 CDS YP_880143.1 118465620 4528736 complement(820863..821540) 1 NC_008595.1 identified by match to protein family HMM PF01614; transcriptional regulator 821540 4528736 MAV_0876 Mycobacterium avium 104 transcriptional regulator YP_880143.1 820863 R 243243 CDS YP_880144.1 118465071 4525888 821666..822529 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase 822529 4525888 MAV_0877 Mycobacterium avium 104 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase YP_880144.1 821666 D 243243 CDS YP_880145.1 118466735 4530673 822529..824271 1 NC_008595.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 824271 mhpA 4530673 mhpA Mycobacterium avium 104 3-(3-hydroxyphenyl)propionate hydroxylase YP_880145.1 822529 D 243243 CDS YP_880146.1 118466534 4527002 825132..826859 1 NC_008595.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 826859 4527002 MAV_0880 Mycobacterium avium 104 3-ketosteroid-delta-1-dehydrogenase YP_880146.1 825132 D 243243 CDS YP_880147.1 118464252 4527437 826863..828173 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 828173 4527437 MAV_0881 Mycobacterium avium 104 hypothetical protein YP_880147.1 826863 D 243243 CDS YP_880148.1 118465444 4527313 828199..829026 1 NC_008595.1 catalyzes the formation of 5-alpha-androstane-3,17-dione from androsterone; Acts on other 3-alpha-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin.; 3-alpha-hydroxysteroid dehydrogenase 829026 4527313 MAV_0882 Mycobacterium avium 104 3-alpha-hydroxysteroid dehydrogenase YP_880148.1 828199 D 243243 CDS YP_880149.1 118463094 4528917 829014..830003 1 NC_008595.1 identified by match to protein family HMM PF04199; cyclase 830003 4528917 MAV_0883 Mycobacterium avium 104 cyclase YP_880149.1 829014 D 243243 CDS YP_880150.1 118463511 4527691 830016..830837 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 830837 4527691 MAV_0884 Mycobacterium avium 104 alpha/beta hydrolase YP_880150.1 830016 D 243243 CDS YP_880151.1 118466265 4527817 832658..833464 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 833464 4527817 MAV_0886 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_880151.1 832658 D 243243 CDS YP_880152.1 118464704 4527893 833527..834204 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 834204 4527893 MAV_0887 Mycobacterium avium 104 TetR family transcriptional regulator YP_880152.1 833527 D 243243 CDS YP_880153.1 118465279 4527300 834223..834411 1 NC_008595.1 hypothetical protein 834411 4527300 MAV_0888 Mycobacterium avium 104 hypothetical protein YP_880153.1 834223 D 243243 CDS YP_880154.1 118463430 4528309 835828..836889 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 836889 4528309 MAV_0890 Mycobacterium avium 104 amidohydrolase YP_880154.1 835828 D 243243 CDS YP_880155.1 118466923 4529470 836889..838142 1 NC_008595.1 identified by match to protein family HMM PF00557; peptidase, M24 family protein 838142 4529470 MAV_0891 Mycobacterium avium 104 peptidase, M24 family protein YP_880155.1 836889 D 243243 CDS YP_880156.1 118466379 4526180 838132..839259 1 NC_008595.1 identified by match to protein family HMM PF00557; peptidase, M24 family protein 839259 4526180 MAV_0892 Mycobacterium avium 104 peptidase, M24 family protein YP_880156.1 838132 D 243243 CDS YP_880157.1 118463219 4528793 839292..841709 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 841709 4528793 MAV_0893 Mycobacterium avium 104 caib/baif family protein YP_880157.1 839292 D 243243 CDS YP_880158.1 118462664 4529092 841716..842525 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 842525 4529092 MAV_0894 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_880158.1 841716 D 243243 CDS YP_880159.1 118465477 4527230 complement(842572..843414) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 843414 4527230 MAV_0895 Mycobacterium avium 104 short chain dehydrogenase YP_880159.1 842572 R 243243 CDS YP_880160.1 118463635 4527339 complement(843426..844274) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 844274 4527339 MAV_0896 Mycobacterium avium 104 carveol dehydrogenase YP_880160.1 843426 R 243243 CDS YP_880161.1 118462441 4525614 845408..846583 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 846583 4525614 MAV_0898 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880161.1 845408 D 243243 CDS YP_880162.1 118466825 4527390 complement(846592..846861) 1 NC_008595.1 hypothetical protein 846861 4527390 MAV_0899 Mycobacterium avium 104 hypothetical protein YP_880162.1 846592 R 243243 CDS YP_880163.1 118464346 4529148 complement(846937..847755) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 847755 4529148 MAV_0900 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880163.1 846937 R 243243 CDS YP_880164.1 118463764 4528008 complement(847759..848856) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 848856 4528008 MAV_0901 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880164.1 847759 R 243243 CDS YP_880165.1 118466501 4525584 complement(848877..849323) 1 NC_008595.1 hypothetical protein 849323 4525584 MAV_0902 Mycobacterium avium 104 hypothetical protein YP_880165.1 848877 R 243243 CDS YP_880166.1 118465964 4528183 complement(849304..850533) 1 NC_008595.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; Xaa-Pro dipeptidase 850533 4528183 MAV_0903 Mycobacterium avium 104 Xaa-Pro dipeptidase YP_880166.1 849304 R 243243 CDS YP_880167.1 118467272 4527074 complement(850536..850865) 1 NC_008595.1 hypothetical protein 850865 4527074 MAV_0904 Mycobacterium avium 104 hypothetical protein YP_880167.1 850536 R 243243 CDS YP_880168.1 118466700 4529707 complement(850843..852126) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 852126 4529707 MAV_0905 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880168.1 850843 R 243243 CDS YP_880169.1 118462882 4527488 complement(852145..852678) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 852678 pcaC 4527488 pcaC Mycobacterium avium 104 hypothetical protein YP_880169.1 852145 R 243243 CDS YP_880170.1 118462418 4525728 852999..854297 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 854297 4525728 MAV_0907 Mycobacterium avium 104 amidohydrolase YP_880170.1 852999 D 243243 CDS YP_880171.1 118465912 4528994 855668..856822 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 856822 4528994 MAV_0909 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880171.1 855668 D 243243 CDS YP_880172.1 118465376 4529667 856928..857542 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 857542 4529667 MAV_0910 Mycobacterium avium 104 TetR family transcriptional regulator YP_880172.1 856928 D 243243 CDS YP_880173.1 118467087 4526387 857539..858066 1 NC_008595.1 hypothetical protein 858066 4526387 MAV_0911 Mycobacterium avium 104 hypothetical protein YP_880173.1 857539 D 243243 CDS YP_880174.1 118466476 4527606 858205..859479 1 NC_008595.1 cytochrome p450 859479 4527606 MAV_0912 Mycobacterium avium 104 cytochrome p450 YP_880174.1 858205 D 243243 CDS YP_880175.1 118462962 4526330 859518..859664 1 NC_008595.1 hypothetical protein 859664 4526330 MAV_0913 Mycobacterium avium 104 hypothetical protein YP_880175.1 859518 D 243243 CDS YP_880176.1 118462413 4525723 859685..859978 1 NC_008595.1 identified by match to protein family HMM PF07045; hypothetical protein 859978 4525723 MAV_0914 Mycobacterium avium 104 hypothetical protein YP_880176.1 859685 D 243243 CDS YP_880177.1 118464135 4528837 complement(859986..860186) 1 NC_008595.1 hypothetical protein 860186 4528837 MAV_0915 Mycobacterium avium 104 hypothetical protein YP_880177.1 859986 R 243243 CDS YP_880178.1 118463579 4529764 complement(860197..861402) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 monooxygenase 861402 4529764 MAV_0916 Mycobacterium avium 104 cytochrome P450 monooxygenase YP_880178.1 860197 R 243243 CDS YP_880179.1 118465272 4527293 complement(861579..862394) 1 NC_008595.1 identified by match to protein family HMM PF03446; match to protein family HMM PF03807; 6-phosphogluconate dehydrogenase 862394 4527293 MAV_0917 Mycobacterium avium 104 6-phosphogluconate dehydrogenase YP_880179.1 861579 R 243243 CDS YP_880180.1 118467249 4526084 complement(862394..863428) 1 NC_008595.1 hypothetical protein 863428 4526084 MAV_0918 Mycobacterium avium 104 hypothetical protein YP_880180.1 862394 R 243243 CDS YP_880181.1 118463938 4528118 complement(863425..865077) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 865077 4528118 MAV_0919 Mycobacterium avium 104 hypothetical protein YP_880181.1 863425 R 243243 CDS YP_880182.1 118466195 4530185 complement(865188..865364) 1 NC_008595.1 hypothetical protein 865364 4530185 MAV_0920 Mycobacterium avium 104 hypothetical protein YP_880182.1 865188 R 243243 CDS YP_880183.1 118464485 4528859 865619..866611 1 NC_008595.1 identified by match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993; hypothetical protein 866611 4528859 MAV_0921 Mycobacterium avium 104 hypothetical protein YP_880183.1 865619 D 243243 CDS YP_880184.1 118465326 4526522 866623..867366 1 NC_008595.1 hypothetical protein 867366 4526522 MAV_0922 Mycobacterium avium 104 hypothetical protein YP_880184.1 866623 D 243243 CDS YP_880185.1 118465901 4528983 867379..868335 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 868335 4528983 MAV_0923 Mycobacterium avium 104 hypothetical protein YP_880185.1 867379 D 243243 CDS YP_880186.1 118465634 4528751 complement(868339..868635) 1 NC_008595.1 hypothetical protein 868635 4528751 MAV_0924 Mycobacterium avium 104 hypothetical protein YP_880186.1 868339 R 243243 CDS YP_880187.1 118463353 4529887 complement(868632..869942) 1 NC_008595.1 identified by match to protein family HMM PF01512; respiratory-chain NADH dehydrogenase 51 kd subunit family protein 869942 4529887 MAV_0925 Mycobacterium avium 104 respiratory-chain NADH dehydrogenase 51 kd subunit family protein YP_880187.1 868632 R 243243 CDS YP_880188.1 118466630 4526986 869991..870452 1 NC_008595.1 hypothetical protein 870452 4526986 MAV_0926 Mycobacterium avium 104 hypothetical protein YP_880188.1 869991 D 243243 CDS YP_880189.1 118462262 4526405 complement(870458..871324) 1 NC_008595.1 hypothetical protein 871324 4526405 MAV_0927 Mycobacterium avium 104 hypothetical protein YP_880189.1 870458 R 243243 CDS YP_880190.1 118462949 4530234 complement(871340..871753) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 871753 4530234 MAV_0928 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880190.1 871340 R 243243 CDS YP_880191.1 118465745 4525708 complement(871755..872897) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 872897 4525708 MAV_0929 Mycobacterium avium 104 amidohydrolase YP_880191.1 871755 R 243243 CDS YP_880192.1 118463526 4526831 complement(872934..874025) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 874025 4526831 MAV_0930 Mycobacterium avium 104 amidohydrolase YP_880192.1 872934 R 243243 CDS YP_880193.1 118465226 4525597 complement(874261..875154) 1 NC_008595.1 identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase 875154 4525597 MAV_0931 Mycobacterium avium 104 3-hydroxyisobutyrate dehydrogenase YP_880193.1 874261 R 243243 CDS YP_880194.1 118466350 4530490 875778..876398 1 NC_008595.1 identified by match to protein family HMM PF00881; nitroreductase 876398 4530490 MAV_0933 Mycobacterium avium 104 nitroreductase YP_880194.1 875778 D 243243 CDS YP_880195.1 118463586 4529771 876520..877518 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 877518 4529771 MAV_0934 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880195.1 876520 D 243243 CDS YP_880196.1 118464305 4526635 877502..878677 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 878677 4526635 MAV_0935 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880196.1 877502 D 243243 CDS YP_880197.1 118465935 4528494 complement(878683..880047) 1 NC_008595.1 identified by match to protein family HMM PF00756; esterase 880047 4528494 MAV_0936 Mycobacterium avium 104 esterase YP_880197.1 878683 R 243243 CDS YP_880198.1 118465083 4525900 complement(880265..880828) 1 NC_008595.1 hypothetical protein 880828 4525900 MAV_0937 Mycobacterium avium 104 hypothetical protein YP_880198.1 880265 R 243243 CDS YP_880199.1 118464140 4528842 complement(880825..881715) 1 NC_008595.1 hypothetical protein 881715 4528842 MAV_0938 Mycobacterium avium 104 hypothetical protein YP_880199.1 880825 R 243243 CDS YP_880200.1 118463866 4527744 complement(881771..882187) 1 NC_008595.1 hypothetical protein 882187 4527744 MAV_0939 Mycobacterium avium 104 hypothetical protein YP_880200.1 881771 R 243243 CDS YP_880201.1 118465966 4528185 complement(882311..883675) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 883675 4528185 MAV_0940 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880201.1 882311 R 243243 CDS YP_880202.1 118465435 4527304 complement(883714..883914) 1 NC_008595.1 hypothetical protein 883914 4527304 MAV_0941 Mycobacterium avium 104 hypothetical protein YP_880202.1 883714 R 243243 CDS YP_880203.1 118466360 4529922 complement(883973..884674) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; 3-oxoacyl-(acyl-carrier-protein) reductase, putative 884674 4529922 MAV_0942 Mycobacterium avium 104 3-oxoacyl-(acyl-carrier-protein) reductase, putative YP_880203.1 883973 R 243243 CDS YP_880204.1 118463878 4527756 884762..884875 1 NC_008595.1 hypothetical protein 884875 4527756 MAV_0943 Mycobacterium avium 104 hypothetical protein YP_880204.1 884762 D 243243 CDS YP_880205.1 118465349 4526662 884926..886497 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase (NAD) family protein 886497 4526662 MAV_0944 Mycobacterium avium 104 aldehyde dehydrogenase (NAD) family protein YP_880205.1 884926 D 243243 CDS YP_880206.1 118463018 4526311 886494..887699 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 887699 4526311 MAV_0945 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_880206.1 886494 D 243243 CDS YP_880207.1 118463749 4528157 888081..888899 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB1 protein 888899 4528157 MAV_0946 Mycobacterium avium 104 TrnB1 protein YP_880207.1 888081 D 243243 CDS YP_880208.1 118466445 4527118 888910..889755 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB2 protein 889755 4527118 MAV_0947 Mycobacterium avium 104 TrnB2 protein YP_880208.1 888910 D 243243 CDS YP_880209.1 118467131 4526158 889775..891037 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 891037 4526158 MAV_0948 Mycobacterium avium 104 virulence factor Mce YP_880209.1 889775 D 243243 CDS YP_880210.1 118465177 4528667 891034..892056 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 892056 4528667 MAV_0949 Mycobacterium avium 104 virulence factor Mce YP_880210.1 891034 D 243243 CDS YP_880211.1 118465942 4527938 892056..893174 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 893174 4527938 MAV_0950 Mycobacterium avium 104 virulence factor Mce YP_880211.1 892056 D 243243 CDS YP_880212.1 118465363 4529223 893171..894598 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 894598 4529223 MAV_0951 Mycobacterium avium 104 virulence factor Mce YP_880212.1 893171 D 243243 CDS YP_880213.1 118463631 4527335 895904..897631 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; mce-family protein mce1f 897631 4527335 MAV_0953 Mycobacterium avium 104 mce-family protein mce1f YP_880213.1 895904 D 243243 CDS YP_880214.1 118465535 4530011 complement(897704..898225) 1 NC_008595.1 hypothetical protein 898225 4530011 MAV_0954 Mycobacterium avium 104 hypothetical protein YP_880214.1 897704 R 243243 CDS YP_880215.1 118464121 4526292 complement(898359..898964) 1 NC_008595.1 hypothetical protein 898964 4526292 MAV_0955 Mycobacterium avium 104 hypothetical protein YP_880215.1 898359 R 243243 CDS YP_880216.1 118464562 4530781 complement(898961..899704) 1 NC_008595.1 hypothetical protein 899704 4530781 MAV_0956 Mycobacterium avium 104 hypothetical protein YP_880216.1 898961 R 243243 CDS YP_880217.1 118463872 4527750 complement(900064..900189) 1 NC_008595.1 hypothetical protein 900189 4527750 MAV_0957 Mycobacterium avium 104 hypothetical protein YP_880217.1 900064 R 243243 CDS YP_880218.1 118464618 4526775 900176..900307 1 NC_008595.1 hypothetical protein 900307 4526775 MAV_0958 Mycobacterium avium 104 hypothetical protein YP_880218.1 900176 D 243243 CDS YP_880219.1 118464860 4530696 complement(900313..900915) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 900915 4530696 MAV_0959 Mycobacterium avium 104 TetR family transcriptional regulator YP_880219.1 900313 R 243243 CDS YP_880220.1 118465523 4528941 901015..901779 1 NC_008595.1 hypothetical protein 901779 4528941 MAV_0960 Mycobacterium avium 104 hypothetical protein YP_880220.1 901015 D 243243 CDS YP_880221.1 118462936 4530221 901785..902582 1 NC_008595.1 hypothetical protein 902582 4530221 MAV_0961 Mycobacterium avium 104 hypothetical protein YP_880221.1 901785 D 243243 CDS YP_880222.1 118464025 4528821 902579..903157 1 NC_008595.1 identified by match to protein family HMM PF00510; cytochrome C oxidase, subunit III 903157 4528821 MAV_0962 Mycobacterium avium 104 cytochrome C oxidase, subunit III YP_880222.1 902579 D 243243 CDS YP_880223.1 118464756 4527652 903161..903439 1 NC_008595.1 hypothetical protein 903439 4527652 MAV_0963 Mycobacterium avium 104 hypothetical protein YP_880223.1 903161 D 243243 CDS YP_880224.1 118467311 4530303 complement(903441..904736) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome p450 904736 4530303 MAV_0964 Mycobacterium avium 104 cytochrome p450 YP_880224.1 903441 R 243243 CDS YP_880225.1 118466137 4527903 904930..905667 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 905667 4527903 MAV_0966 Mycobacterium avium 104 TetR family transcriptional regulator YP_880225.1 904930 D 243243 CDS YP_880226.1 118462977 4527405 complement(905583..906026) 1 NC_008595.1 hypothetical protein 906026 4527405 MAV_0965 Mycobacterium avium 104 hypothetical protein YP_880226.1 905583 R 243243 CDS YP_880227.1 118467199 4528433 complement(906023..906778) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 906778 4528433 MAV_0967 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880227.1 906023 R 243243 CDS YP_880228.1 118464082 4528395 906887..907306 1 NC_008595.1 hypothetical protein 907306 4528395 MAV_0969 Mycobacterium avium 104 hypothetical protein YP_880228.1 906887 D 243243 CDS YP_880229.1 118463506 4527686 complement(907284..907403) 1 NC_008595.1 hypothetical protein 907403 4527686 MAV_0968 Mycobacterium avium 104 hypothetical protein YP_880229.1 907284 R 243243 CDS YP_880230.1 118463192 4527715 907395..908585 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 908585 4527715 MAV_0970 Mycobacterium avium 104 amidohydrolase YP_880230.1 907395 D 243243 CDS YP_880231.1 118463257 4528122 908602..910077 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 910077 4528122 MAV_0971 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_880231.1 908602 D 243243 CDS YP_880232.1 118462546 4530547 910074..910700 1 NC_008595.1 acyl-CoA dehydrogenase 910700 4530547 MAV_0972 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880232.1 910074 D 243243 CDS YP_880233.1 118464764 4527660 910711..910896 1 NC_008595.1 identified by match to protein family HMM PF04324; hypothetical protein 910896 4527660 MAV_0974 Mycobacterium avium 104 hypothetical protein YP_880233.1 910711 D 243243 CDS YP_880234.1 118464281 4529569 complement(910893..912578) 1 NC_008595.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; indole-3-pyruvate decarboxylase 912578 4529569 MAV_0973 Mycobacterium avium 104 indole-3-pyruvate decarboxylase YP_880234.1 910893 R 243243 CDS YP_880235.1 118465100 4529991 912644..913087 1 NC_008595.1 similar to streptomyces cyclase/dehydrase; identified by match to protein family HMM PF03364; cyclase/dehydrase 913087 4529991 MAV_0975 Mycobacterium avium 104 cyclase/dehydrase YP_880235.1 912644 D 243243 CDS YP_880236.1 118465733 4525696 913093..914172 1 NC_008595.1 identified by match to protein family HMM PF02515; alpha-methylacyl-CoA racemase 914172 4525696 MAV_0976 Mycobacterium avium 104 alpha-methylacyl-CoA racemase YP_880236.1 913093 D 243243 CDS YP_880237.1 118464933 4528573 914230..914694 1 NC_008595.1 similar to streptomyces cyclase/dehydrase; identified by match to protein family HMM PF03364; cyclase/dehydrase 914694 4528573 MAV_0977 Mycobacterium avium 104 cyclase/dehydrase YP_880237.1 914230 D 243243 CDS YP_880238.1 118467176 4530146 914701..915156 1 NC_008595.1 hypothetical protein 915156 4530146 MAV_0978 Mycobacterium avium 104 hypothetical protein YP_880238.1 914701 D 243243 CDS YP_880239.1 118463944 4526596 complement(915158..916339) 1 NC_008595.1 identified by match to protein family HMM PF00155; aminotransferase 916339 4526596 MAV_0979 Mycobacterium avium 104 aminotransferase YP_880239.1 915158 R 243243 CDS YP_880240.1 118463531 4526836 916773..917984 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 917984 4526836 MAV_0980 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880240.1 916773 D 243243 CDS YP_880241.1 118464428 4530249 917989..920136 1 NC_008595.1 identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737; acyl-CoA dehydrogenase 920136 4530249 MAV_0981 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880241.1 917989 D 243243 CDS YP_880242.1 118465180 4528670 complement(920214..920816) 1 NC_008595.1 identified by match to protein family HMM PF05724; methyltransferase type 12 920816 4528670 MAV_0982 Mycobacterium avium 104 methyltransferase type 12 YP_880242.1 920214 R 243243 CDS YP_880243.1 118465895 4527929 complement(920866..921726) 1 NC_008595.1 hypothetical protein 921726 4527929 MAV_0983 Mycobacterium avium 104 hypothetical protein YP_880243.1 920866 R 243243 CDS YP_880244.1 118466569 4529118 complement(921758..922966) 1 NC_008595.1 hypothetical protein 922966 4529118 MAV_0984 Mycobacterium avium 104 hypothetical protein YP_880244.1 921758 R 243243 CDS YP_880245.1 118467282 4527084 923118..923594 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 923594 4527084 MAV_0985 Mycobacterium avium 104 TetR family transcriptional regulator YP_880245.1 923118 D 243243 CDS YP_880246.1 118463136 4529661 923591..924628 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 924628 4529661 MAV_0986 Mycobacterium avium 104 hypothetical protein YP_880246.1 923591 D 243243 CDS YP_880247.1 118463774 4530125 complement(924653..924946) 1 NC_008595.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase domain-containing protein 924946 4530125 MAV_0987 Mycobacterium avium 104 antibiotic biosynthesis monooxygenase domain-containing protein YP_880247.1 924653 R 243243 CDS YP_880248.1 118465194 4530391 925098..925511 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 925511 4530391 MAV_0988 Mycobacterium avium 104 hypothetical protein YP_880248.1 925098 D 243243 CDS YP_880249.1 118462649 4529390 925523..926668 1 NC_008595.1 identified by match to protein family HMM PF02803; thiolase 926668 4529390 MAV_0989 Mycobacterium avium 104 thiolase YP_880249.1 925523 D 243243 CDS YP_880250.1 118466248 4526867 complement(926756..928405) 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; DNA or RNA helicase of superfamily protein II 928405 4526867 MAV_0990 Mycobacterium avium 104 DNA or RNA helicase of superfamily protein II YP_880250.1 926756 R 243243 CDS YP_880251.1 118465684 4525743 complement(928446..930704) 1 NC_008595.1 hypothetical protein 930704 4525743 MAV_0991 Mycobacterium avium 104 hypothetical protein YP_880251.1 928446 R 243243 CDS YP_880252.1 118465512 4528929 930834..931034 1 NC_008595.1 hypothetical protein 931034 4528929 MAV_0992 Mycobacterium avium 104 hypothetical protein YP_880252.1 930834 D 243243 CDS YP_880253.1 118464937 4528198 931145..931573 1 NC_008595.1 identified by match to protein family HMM PF01967; match to protein family HMM TIGR00581; molybdenum cofactor biosynthesis protein C 931573 moaC 4528198 moaC Mycobacterium avium 104 molybdenum cofactor biosynthesis protein C YP_880253.1 931145 D 243243 CDS YP_880254.1 118464688 4527877 931570..932052 1 NC_008595.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdenum cofactor synthesis domain-containing protein 932052 4527877 MAV_0994 Mycobacterium avium 104 molybdenum cofactor synthesis domain-containing protein YP_880254.1 931570 D 243243 CDS YP_880255.1 118464103 4525864 932049..932474 1 NC_008595.1 identified by match to protein family HMM PF02391; molybdopterin converting factor, subunit 2 932474 moaE 4525864 moaE Mycobacterium avium 104 molybdopterin converting factor, subunit 2 YP_880255.1 932049 D 243243 CDS YP_880256.1 118466909 4529453 complement(932553..933257) 1 NC_008595.1 identified by match to protein family HMM PF06737; resuscitation-promoting factor RpfA 933257 4529453 MAV_0996 Mycobacterium avium 104 resuscitation-promoting factor RpfA YP_880256.1 932553 R 243243 CDS YP_880257.1 118466373 4529935 complement(933760..934038) 1 NC_008595.1 identified by match to protein family HMM PF02597; ThiS family protein 934038 4529935 MAV_0997 Mycobacterium avium 104 ThiS family protein YP_880257.1 933760 R 243243 CDS YP_880258.1 118465617 4528733 complement(935133..935540) 1 NC_008595.1 identified by match to protein family HMM PF03733; hypothetical protein 935540 4528733 MAV_0999 Mycobacterium avium 104 hypothetical protein YP_880258.1 935133 R 243243 CDS YP_880259.1 118466199 4530189 935704..936111 1 NC_008595.1 identified by match to protein family HMM PF00313; cold shock DNA-binding domain-containing protein 936111 4530189 MAV_1000 Mycobacterium avium 104 cold shock DNA-binding domain-containing protein YP_880259.1 935704 D 243243 CDS YP_880260.1 118463616 4527320 936210..938138 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 938138 4527320 MAV_1001 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880260.1 936210 D 243243 CDS YP_880261.1 118466876 4526695 938186..939190 1 NC_008595.1 glutathione S-transferase 939190 4526695 MAV_1003 Mycobacterium avium 104 glutathione S-transferase YP_880261.1 938186 D 243243 CDS YP_880262.1 118462486 4530682 complement(939187..940068) 1 NC_008595.1 hypothetical protein 940068 4530682 MAV_1002 Mycobacterium avium 104 hypothetical protein YP_880262.1 939187 R 243243 CDS YP_880263.1 118466456 4528677 complement(940261..940761) 1 NC_008595.1 hypothetical protein 940761 4528677 MAV_1004 Mycobacterium avium 104 hypothetical protein YP_880263.1 940261 R 243243 CDS YP_880264.1 118467188 4528422 complement(940758..942461) 1 NC_008595.1 hypothetical protein 942461 4528422 MAV_1005 Mycobacterium avium 104 hypothetical protein YP_880264.1 940758 R 243243 CDS YP_880265.1 118464954 4528694 942511..943404 1 NC_008595.1 hypothetical protein 943404 4528694 MAV_1007 Mycobacterium avium 104 hypothetical protein YP_880265.1 942511 D 243243 CDS YP_880266.1 118463946 4526598 complement(943401..943865) 1 NC_008595.1 hypothetical protein 943865 4526598 MAV_1006 Mycobacterium avium 104 hypothetical protein YP_880266.1 943401 R 243243 CDS YP_880267.1 118465635 4526160 complement(943889..944164) 1 NC_008595.1 hypothetical protein 944164 4526160 MAV_1008 Mycobacterium avium 104 hypothetical protein YP_880267.1 943889 R 243243 CDS YP_880268.1 118466066 4530036 944368..945666 1 NC_008595.1 identified by match to protein family HMM PF00588; match to protein family HMM PF01047; SpoU rRNA methylase 945666 4530036 MAV_1009 Mycobacterium avium 104 SpoU rRNA methylase YP_880268.1 944368 D 243243 CDS YP_880269.1 118466549 4527017 945650..945949 1 NC_008595.1 hypothetical protein 945949 4527017 MAV_1011 Mycobacterium avium 104 hypothetical protein YP_880269.1 945650 D 243243 CDS YP_880270.1 118463429 4528308 complement(945946..946725) 1 NC_008595.1 hypothetical protein 946725 4528308 MAV_1010 Mycobacterium avium 104 hypothetical protein YP_880270.1 945946 R 243243 CDS YP_880271.1 118464824 4529726 complement(946848..947972) 1 NC_008595.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 947972 4529726 MAV_1012 Mycobacterium avium 104 phosphoserine aminotransferase YP_880271.1 946848 R 243243 CDS YP_880272.1 118466802 4529048 948228..949238 1 NC_008595.1 hypothetical protein 949238 4529048 MAV_1013 Mycobacterium avium 104 hypothetical protein YP_880272.1 948228 D 243243 CDS YP_880273.1 118463699 4530586 949316..950956 1 NC_008595.1 identified by match to protein family HMM PF00037; match to protein family HMM PF07992; ferredoxin/ferredoxin--NADP reductase 950956 4530586 MAV_1015 Mycobacterium avium 104 ferredoxin/ferredoxin--NADP reductase YP_880273.1 949316 D 243243 CDS YP_880274.1 118465682 4525741 complement(950953..951429) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 951429 4525741 MAV_1014 Mycobacterium avium 104 glyoxalase YP_880274.1 950953 R 243243 CDS YP_880275.1 118464527 4529447 complement(951557..952678) 1 NC_008595.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 952678 4529447 MAV_1016 Mycobacterium avium 104 citrate synthase 2 YP_880275.1 951557 R 243243 CDS YP_880276.1 118464500 4525543 952789..953412 1 NC_008595.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 953412 pdxH 4525543 pdxH Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_880276.1 952789 D 243243 CDS YP_880277.1 118462332 4525677 complement(954852..956402) 1 NC_008595.1 phytoene dehydrogenase 956402 4525677 MAV_1019 Mycobacterium avium 104 phytoene dehydrogenase YP_880277.1 954852 R 243243 CDS YP_880278.1 118466627 4526981 complement(956429..956692) 1 NC_008595.1 hypothetical protein 956692 4526981 MAV_1020 Mycobacterium avium 104 hypothetical protein YP_880278.1 956429 R 243243 CDS YP_880279.1 118464817 4527636 complement(956792..958129) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 958129 4527636 MAV_1021 Mycobacterium avium 104 sensor histidine kinase YP_880279.1 956792 R 243243 CDS YP_880280.1 118465275 4527296 complement(958145..958846) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; PrrA family transcriptional regulator 958846 4527296 MAV_1022 Mycobacterium avium 104 PrrA family transcriptional regulator YP_880280.1 958145 R 243243 CDS YP_880281.1 118465861 4530655 complement(958852..960126) 1 NC_008595.1 identified by match to protein family HMM PF07690; MFS transporter 960126 4530655 MAV_1023 Mycobacterium avium 104 MFS transporter YP_880281.1 958852 R 243243 CDS YP_880282.1 118464465 4527058 960284..961474 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 961474 4527058 MAV_1024 Mycobacterium avium 104 glycosyl transferase, group 1 family protein YP_880282.1 960284 D 243243 CDS YP_880283.1 118462600 4528504 961471..963591 1 NC_008595.1 hypothetical protein 963591 4528504 MAV_1025 Mycobacterium avium 104 hypothetical protein YP_880283.1 961471 D 243243 CDS YP_880284.1 118462286 4529291 965590..966321 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 966321 4529291 MAV_1028 Mycobacterium avium 104 enoyl-CoA hydratase YP_880284.1 965590 D 243243 CDS YP_880285.1 118463201 4527528 966327..967436 1 NC_008595.1 metallo-beta-lactamase 967436 4527528 MAV_1029 Mycobacterium avium 104 metallo-beta-lactamase YP_880285.1 966327 D 243243 CDS YP_880286.1 118463767 4528011 967466..969052 1 NC_008595.1 identified by match to protein family HMM PF00144; penicillin-binding protein 4 969052 4528011 MAV_1030 Mycobacterium avium 104 penicillin-binding protein 4 YP_880286.1 967466 D 243243 CDS YP_880287.1 118464682 4528377 969049..971421 1 NC_008595.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; cation-transporting ATPase Exp7 971421 4528377 MAV_1031 Mycobacterium avium 104 cation-transporting ATPase Exp7 YP_880287.1 969049 D 243243 CDS YP_880288.1 118464529 4529449 971484..971672 1 NC_008595.1 hypothetical protein 971672 4529449 MAV_1032 Mycobacterium avium 104 hypothetical protein YP_880288.1 971484 D 243243 CDS YP_880289.1 118465659 4526731 971676..972137 1 NC_008595.1 hypothetical protein 972137 4526731 MAV_1033 Mycobacterium avium 104 hypothetical protein YP_880289.1 971676 D 243243 CDS YP_880290.1 118464875 4530711 972251..972640 1 NC_008595.1 hypothetical protein 972640 4530711 MAV_1034 Mycobacterium avium 104 hypothetical protein YP_880290.1 972251 D 243243 CDS YP_880291.1 118466701 4529708 973637..975220 1 NC_008595.1 hypothetical protein 975220 4529708 MAV_1035 Mycobacterium avium 104 hypothetical protein YP_880291.1 973637 D 243243 CDS YP_880292.1 118466252 4526871 975267..975653 1 NC_008595.1 hypothetical protein 975653 4526871 MAV_1036 Mycobacterium avium 104 hypothetical protein YP_880292.1 975267 D 243243 CDS YP_880293.1 118464799 4526723 complement(975688..975867) 1 NC_008595.1 hypothetical protein 975867 4526723 MAV_1037 Mycobacterium avium 104 hypothetical protein YP_880293.1 975688 R 243243 CDS YP_880294.1 118466187 4526218 complement(976139..976243) 1 NC_008595.1 hypothetical protein 976243 4526218 MAV_1038 Mycobacterium avium 104 hypothetical protein YP_880294.1 976139 R 243243 CDS YP_880295.1 118463366 4529900 976490..976777 1 NC_008595.1 hypothetical protein 976777 4529900 MAV_1039 Mycobacterium avium 104 hypothetical protein YP_880295.1 976490 D 243243 CDS YP_880296.1 118462629 4526431 977169..977321 1 NC_008595.1 hypothetical protein 977321 4526431 MAV_1040 Mycobacterium avium 104 hypothetical protein YP_880296.1 977169 D 243243 CDS YP_880297.1 118462803 4529023 complement(977654..978472) 1 NC_008595.1 hypothetical protein 978472 4529023 MAV_1042 Mycobacterium avium 104 hypothetical protein YP_880297.1 977654 R 243243 CDS YP_880298.1 118465094 4529985 complement(978486..979565) 1 NC_008595.1 identified by match to protein family HMM PF05908; hypothetical protein 979565 4529985 MAV_1043 Mycobacterium avium 104 hypothetical protein YP_880298.1 978486 R 243243 CDS YP_880299.1 118463885 4530562 complement(979566..980792) 1 NC_008595.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 980792 4530562 MAV_1044 Mycobacterium avium 104 manganese transport protein MntH YP_880299.1 979566 R 243243 CDS YP_880300.1 118462778 4527275 complement(980889..981965) 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 981965 dapB 4527275 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_880300.1 980889 R 243243 CDS YP_880301.1 118466704 4529711 complement(981990..982781) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 982781 4529711 MAV_1046 Mycobacterium avium 104 short chain dehydrogenase YP_880301.1 981990 R 243243 CDS YP_880302.1 118463278 4530526 983274..984383 1 NC_008595.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter phosphate-binding protein PstS 984383 pstS 4530526 pstS Mycobacterium avium 104 phosphate ABC transporter phosphate-binding protein PstS YP_880302.1 983274 D 243243 CDS YP_880303.1 118465658 4526730 984390..985376 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 985376 pstC 4526730 pstC Mycobacterium avium 104 phosphate ABC transporter permease YP_880303.1 984390 D 243243 CDS YP_880304.1 118465812 4525914 985373..986281 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 986281 pstA 4525914 pstA Mycobacterium avium 104 phosphate ABC transporter permease YP_880304.1 985373 D 243243 CDS YP_880305.1 118464480 4528854 complement(986287..987195) 1 NC_008595.1 identified by match to protein family HMM PF02735; match to protein family HMM TIGR02772; Ku protein 987195 4528854 MAV_1050 Mycobacterium avium 104 Ku protein YP_880305.1 986287 R 243243 CDS YP_880306.1 118464900 4530735 complement(987233..988141) 1 NC_008595.1 identified by match to protein family HMM PF00294; kinase, PfkB family protein 988141 4530735 MAV_1051 Mycobacterium avium 104 kinase, PfkB family protein YP_880306.1 987233 R 243243 CDS YP_880307.1 118462317 4529635 complement(988138..989550) 1 NC_008595.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol 2-dehydrogenase 989550 4529635 MAV_1052 Mycobacterium avium 104 mannitol 2-dehydrogenase YP_880307.1 988138 R 243243 CDS YP_880308.1 118462926 4526017 complement(989678..990538) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; hypothetical protein 990538 4526017 MAV_1053 Mycobacterium avium 104 hypothetical protein YP_880308.1 989678 R 243243 CDS YP_880309.1 118466659 4528098 complement(990535..991935) 1 NC_008595.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; D-mannonate oxidoreductase 991935 4528098 MAV_1054 Mycobacterium avium 104 D-mannonate oxidoreductase YP_880309.1 990535 R 243243 CDS YP_880310.1 118462863 4527090 complement(992070..992237) 1 NC_008595.1 hypothetical protein 992237 4527090 MAV_1055 Mycobacterium avium 104 hypothetical protein YP_880310.1 992070 R 243243 CDS YP_880311.1 118467268 4527070 992307..994607 1 NC_008595.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase 994607 4527070 MAV_1056 Mycobacterium avium 104 ATP-dependent DNA ligase YP_880311.1 992307 D 243243 CDS YP_880312.1 118462680 4530607 994604..996541 1 NC_008595.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01557; fumarylacetoacetate hydrolase, putative 996541 4530607 MAV_1057 Mycobacterium avium 104 fumarylacetoacetate hydrolase, putative YP_880312.1 994604 D 243243 CDS YP_880313.1 118463466 4525519 complement(996559..997473) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 997473 4525519 MAV_1058 Mycobacterium avium 104 methyltransferase, putative, family protein YP_880313.1 996559 R 243243 CDS YP_880314.1 118466651 4528089 complement(997488..998540) 1 NC_008595.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; transposase 998540 4528089 MAV_1059 Mycobacterium avium 104 transposase YP_880314.1 997488 R 243243 CDS YP_880315.1 118463173 4529875 998830..999627 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 999627 4529875 MAV_1060 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880315.1 998830 D 243243 CDS YP_880316.1 118467043 4526499 complement(999662..1000528) 1 NC_008595.1 hypothetical protein 1000528 4526499 MAV_1061 Mycobacterium avium 104 hypothetical protein YP_880316.1 999662 R 243243 CDS YP_880317.1 118462473 4528727 complement(1000630..1001328) 1 NC_008595.1 identified by match to protein family HMM PF01740; stas domain-containing protein 1001328 4528727 MAV_1062 Mycobacterium avium 104 stas domain-containing protein YP_880317.1 1000630 R 243243 CDS YP_880318.1 118466333 4528764 complement(1002978..1003928) 1 NC_008595.1 hypothetical protein 1003928 4528764 MAV_1064 Mycobacterium avium 104 hypothetical protein YP_880318.1 1002978 R 243243 CDS YP_880319.1 118466871 4526689 1004044..1004787 1 NC_008595.1 catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase 1004787 cobF 4526689 cobF Mycobacterium avium 104 precorrin 6A synthase YP_880319.1 1004044 D 243243 CDS YP_880320.1 118464184 4529295 1004792..1005655 1 NC_008595.1 identified by match to protein family HMM PF01149; match to protein family HMM PF06831; formamidopyrimidine-DNA glycosylase 1005655 4529295 MAV_1066 Mycobacterium avium 104 formamidopyrimidine-DNA glycosylase YP_880320.1 1004792 D 243243 CDS YP_880321.1 118464136 4528838 1005686..1006447 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1006447 4528838 MAV_1067 Mycobacterium avium 104 short chain dehydrogenase YP_880321.1 1005686 D 243243 CDS YP_880322.1 118464297 4529585 complement(1006449..1008113) 1 NC_008595.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1008113 pgi 4529585 pgi Mycobacterium avium 104 glucose-6-phosphate isomerase YP_880322.1 1006449 R 243243 CDS YP_880323.1 118463684 4528531 complement(1008225..1008497) 1 NC_008595.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01808; hypothetical protein 1008497 4528531 MAV_1069 Mycobacterium avium 104 hypothetical protein YP_880323.1 1008225 R 243243 CDS YP_880324.1 118466319 4528361 1008771..1008911 1 NC_008595.1 hypothetical protein 1008911 4528361 MAV_1070 Mycobacterium avium 104 hypothetical protein YP_880324.1 1008771 D 243243 CDS YP_880325.1 118466048 4528056 1008924..1011248 1 NC_008595.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 1011248 pcrA 4528056 pcrA Mycobacterium avium 104 ATP-dependent DNA helicase PcrA YP_880325.1 1008924 D 243243 CDS YP_880326.1 118464849 4527965 complement(1011322..1011912) 1 NC_008595.1 hypothetical protein 1011912 4527965 MAV_1072 Mycobacterium avium 104 hypothetical protein YP_880326.1 1011322 R 243243 CDS YP_880327.1 118467033 4526546 complement(1011914..1012966) 1 NC_008595.1 identified by match to protein family HMM PF01551; M23 peptidase domain-containing protein 1012966 4526546 MAV_1073 Mycobacterium avium 104 M23 peptidase domain-containing protein YP_880327.1 1011914 R 243243 CDS YP_880328.1 118466486 4527616 1013290..1014453 1 NC_008595.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1014453 sucC 4527616 sucC Mycobacterium avium 104 succinyl-CoA synthetase subunit beta YP_880328.1 1013290 D 243243 CDS YP_880329.1 118462581 4530201 1014466..1015368 1 NC_008595.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1015368 4530201 MAV_1075 Mycobacterium avium 104 succinyl-CoA synthetase subunit alpha YP_880329.1 1014466 D 243243 CDS YP_880330.1 118463301 4525996 1015429..1016955 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1016955 4525996 MAV_1076 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880330.1 1015429 D 243243 CDS YP_880331.1 118463599 4527546 complement(1017007..1017840) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 1017840 4527546 MAV_1077 Mycobacterium avium 104 hypothetical protein YP_880331.1 1017007 R 243243 CDS YP_880332.1 118464677 4528372 1018099..1019007 1 NC_008595.1 34 kDa antigenic protein 1019007 4528372 MAV_1078 Mycobacterium avium 104 34 kDa antigenic protein YP_880332.1 1018099 D 243243 CDS YP_880333.1 118462881 4527487 1019054..1020445 1 NC_008595.1 hypothetical protein 1020445 4527487 MAV_1079 Mycobacterium avium 104 hypothetical protein YP_880333.1 1019054 D 243243 CDS YP_880334.1 118462306 4525651 1020670..1021299 1 NC_008595.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1021299 purN 4525651 purN Mycobacterium avium 104 phosphoribosylglycinamide formyltransferase YP_880334.1 1020670 D 243243 CDS YP_880335.1 118466500 4525583 1021296..1022897 1 NC_008595.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1022897 purH 4525583 purH Mycobacterium avium 104 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_880335.1 1021296 D 243243 CDS YP_880336.1 118465881 4527523 1023081..1023659 1 NC_008595.1 hypothetical protein 1023659 4527523 MAV_1082 Mycobacterium avium 104 hypothetical protein YP_880336.1 1023081 D 243243 CDS YP_880337.1 118463722 4528072 1025217..1027133 1 NC_008595.1 von Willebrand factor type A 1027133 4528072 MAV_1084 Mycobacterium avium 104 von Willebrand factor type A YP_880337.1 1025217 D 243243 CDS YP_880338.1 118466150 4528772 1027182..1028030 1 NC_008595.1 identified by match to protein family HMM PF00248; morphine 6-dehydrogenase 1028030 4528772 MAV_1085 Mycobacterium avium 104 morphine 6-dehydrogenase YP_880338.1 1027182 D 243243 CDS YP_880339.1 118463156 4527794 complement(1028091..1028696) 1 NC_008595.1 identified by match to protein family HMM PF08044; hypothetical protein 1028696 4527794 MAV_1086 Mycobacterium avium 104 hypothetical protein YP_880339.1 1028091 R 243243 CDS YP_880340.1 118462800 4525769 complement(1028827..1029618) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1029618 4525769 MAV_1087 Mycobacterium avium 104 enoyl-CoA hydratase YP_880340.1 1028827 R 243243 CDS YP_880341.1 118463384 4528962 complement(1029623..1030789) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase fadE12 1030789 4528962 MAV_1088 Mycobacterium avium 104 acyl-CoA dehydrogenase fadE12 YP_880341.1 1029623 R 243243 CDS YP_880342.1 118466401 4526243 complement(1030786..1032777) 1 NC_008595.1 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; carbamoyl-phosphate synthase L subunit 1032777 4526243 MAV_1089 Mycobacterium avium 104 carbamoyl-phosphate synthase L subunit YP_880342.1 1030786 R 243243 CDS YP_880343.1 118466323 4528754 complement(1032783..1034378) 1 NC_008595.1 identified by match to protein family HMM PF01039; acetyl-CoA carboxylase carboxyltransferase 1034378 4528754 MAV_1090 Mycobacterium avium 104 acetyl-CoA carboxylase carboxyltransferase YP_880343.1 1032783 R 243243 CDS YP_880344.1 118466999 4529527 complement(1034375..1035523) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1035523 4529527 MAV_1091 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880344.1 1034375 R 243243 CDS YP_880345.1 118464853 4527969 complement(1035520..1037241) 1 NC_008595.1 identified by match to protein family HMM PF07287; hypothetical protein 1037241 4527969 MAV_1092 Mycobacterium avium 104 hypothetical protein YP_880345.1 1035520 R 243243 CDS YP_880346.1 118465546 4525794 1037472..1037645 1 NC_008595.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1037645 rpmF 4525794 rpmF Mycobacterium avium 104 50S ribosomal protein L32 YP_880346.1 1037472 D 243243 CDS YP_880347.1 118464125 4526296 1037761..1038447 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two component response transcriptional regulator MprA 1038447 4526296 MAV_1094 Mycobacterium avium 104 two component response transcriptional regulator MprA YP_880347.1 1037761 D 243243 CDS YP_880348.1 118464607 4530118 1038545..1040032 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 1040032 4530118 MAV_1095 Mycobacterium avium 104 sensor histidine kinase YP_880348.1 1038545 D 243243 CDS YP_880349.1 118462567 4528626 1040115..1041581 1 NC_008595.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; protease 1041581 4528626 MAV_1096 Mycobacterium avium 104 protease YP_880349.1 1040115 D 243243 CDS YP_880350.1 118464669 4528364 1041641..1042138 1 NC_008595.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdenum cofactor synthesis protein 1042138 4528364 MAV_1097 Mycobacterium avium 104 molybdenum cofactor synthesis protein YP_880350.1 1041641 D 243243 CDS YP_880351.1 118463897 4530574 complement(1042163..1042618) 1 NC_008595.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1042618 mscL 4530574 mscL Mycobacterium avium 104 large-conductance mechanosensitive channel YP_880351.1 1042163 R 243243 CDS YP_880352.1 118465730 4527465 complement(1042686..1043366) 1 NC_008595.1 hypothetical protein 1043366 4527465 MAV_1099 Mycobacterium avium 104 hypothetical protein YP_880352.1 1042686 R 243243 CDS YP_880353.1 118467153 4527584 complement(1043431..1043757) 1 NC_008595.1 identified by match to protein family HMM TIGR02605; regulatory protein, FmdB family protein 1043757 4527584 MAV_1100 Mycobacterium avium 104 regulatory protein, FmdB family protein YP_880353.1 1043431 R 243243 CDS YP_880354.1 118465305 4526559 complement(1043864..1044454) 1 NC_008595.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5,10-methenyltetrahydrofolate synthetase 1044454 4526559 MAV_1101 Mycobacterium avium 104 5,10-methenyltetrahydrofolate synthetase YP_880354.1 1043864 R 243243 CDS YP_880355.1 118466027 4529913 1044546..1045439 1 NC_008595.1 identified by match to protein family HMM PF00483; GalU protein 1045439 4529913 MAV_1102 Mycobacterium avium 104 GalU protein YP_880355.1 1044546 D 243243 CDS YP_880356.1 118464283 4529571 1045567..1046853 1 NC_008595.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein moeA 1046853 4529571 MAV_1103 Mycobacterium avium 104 molybdopterin biosynthesis protein moeA YP_880356.1 1045567 D 243243 CDS YP_880357.1 118462454 4525627 1046874..1047527 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, GNAT family protein 1047527 4525627 MAV_1104 Mycobacterium avium 104 acetyltransferase, GNAT family protein YP_880357.1 1046874 D 243243 CDS YP_880358.1 118463118 4527180 1047772..1048779 1 NC_008595.1 hypothetical protein 1048779 4527180 MAV_1105 Mycobacterium avium 104 hypothetical protein YP_880358.1 1047772 D 243243 CDS YP_880359.1 118467321 4530314 1049237..1049353 1 NC_008595.1 hypothetical protein 1049353 4530314 MAV_1107 Mycobacterium avium 104 hypothetical protein YP_880359.1 1049237 D 243243 CDS YP_880360.1 118466271 4527823 1049395..1050441 1 NC_008595.1 hypothetical protein 1050441 4527823 MAV_1108 Mycobacterium avium 104 hypothetical protein YP_880360.1 1049395 D 243243 CDS YP_880361.1 118463071 4527570 1050448..1051101 1 NC_008595.1 hypothetical protein 1051101 4527570 MAV_1109 Mycobacterium avium 104 hypothetical protein YP_880361.1 1050448 D 243243 CDS YP_880362.1 118463501 4527681 complement(1051258..1051650) 1 NC_008595.1 hypothetical protein 1051650 4527681 MAV_1110 Mycobacterium avium 104 hypothetical protein YP_880362.1 1051258 R 243243 CDS YP_880363.1 118464221 4526901 1051709..1051825 1 NC_008595.1 hypothetical protein 1051825 4526901 MAV_1111 Mycobacterium avium 104 hypothetical protein YP_880363.1 1051709 D 243243 CDS YP_880364.1 118465351 4526664 1052166..1052309 1 NC_008595.1 hypothetical protein 1052309 4526664 MAV_1112 Mycobacterium avium 104 hypothetical protein YP_880364.1 1052166 D 243243 CDS YP_880365.1 118465287 4529323 1052416..1053069 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1053069 4529323 MAV_1113 Mycobacterium avium 104 TetR family transcriptional regulator YP_880365.1 1052416 D 243243 CDS YP_880366.1 118465869 4527511 1053066..1053560 1 NC_008595.1 hypothetical protein 1053560 4527511 MAV_1114 Mycobacterium avium 104 hypothetical protein YP_880366.1 1053066 D 243243 CDS YP_880367.1 118466012 4528457 complement(1053569..1054174) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1054174 4528457 MAV_1115 Mycobacterium avium 104 TetR family transcriptional regulator YP_880367.1 1053569 R 243243 CDS YP_880368.1 118466447 4527120 1054267..1055436 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 1055436 4527120 MAV_1116 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880368.1 1054267 D 243243 CDS YP_880369.1 118467119 4526146 1055506..1056639 1 NC_008595.1 identified by match to protein family HMM PF05343; M42 glutamyl aminopeptidase 1056639 4526146 MAV_1117 Mycobacterium avium 104 M42 glutamyl aminopeptidase YP_880369.1 1055506 D 243243 CDS YP_880370.1 118466738 4526339 1056776..1057792 1 NC_008595.1 identified by match to protein family HMM PF00288; D-glycero-D-manno-heptose 7-phosphate kinase 1057792 4526339 MAV_1118 Mycobacterium avium 104 D-glycero-D-manno-heptose 7-phosphate kinase YP_880370.1 1056776 D 243243 CDS YP_880371.1 118466639 4526995 1057780..1058397 1 NC_008595.1 identified by match to protein family HMM TIGR00441; phosphoheptose isomerase 1058397 gmhA 4526995 gmhA Mycobacterium avium 104 phosphoheptose isomerase YP_880371.1 1057780 D 243243 CDS YP_880372.1 118465609 4527868 1058406..1058972 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; hypothetical protein 1058972 4527868 MAV_1120 Mycobacterium avium 104 hypothetical protein YP_880372.1 1058406 D 243243 CDS YP_880373.1 118466953 4530265 1059139..1060131 1 NC_008595.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00583; cyclic nucleotide-binding protein 1060131 4530265 MAV_1121 Mycobacterium avium 104 cyclic nucleotide-binding protein YP_880373.1 1059139 D 243243 CDS YP_880374.1 118462648 4529389 1060337..1060999 1 NC_008595.1 hypothetical protein 1060999 4529389 MAV_1122 Mycobacterium avium 104 hypothetical protein YP_880374.1 1060337 D 243243 CDS YP_880375.1 118463181 4527704 1061027..1061680 1 NC_008595.1 hypothetical protein 1061680 4527704 MAV_1123 Mycobacterium avium 104 hypothetical protein YP_880375.1 1061027 D 243243 CDS YP_880376.1 118464115 4526286 complement(1061681..1062277) 1 NC_008595.1 alkylated DNA repair protein 1062277 4526286 MAV_1124 Mycobacterium avium 104 alkylated DNA repair protein YP_880376.1 1061681 R 243243 CDS YP_880377.1 118464285 4529573 1062374..1063582 1 NC_008595.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 1063582 arcA 4529573 arcA Mycobacterium avium 104 arginine deiminase YP_880377.1 1062374 D 243243 CDS YP_880378.1 118464554 4530773 complement(1063664..1065223) 1 NC_008595.1 identified by match to protein family HMM PF02366; dolichyl-phosphate-mannose-protein mannosyltransferase 1065223 4530773 MAV_1126 Mycobacterium avium 104 dolichyl-phosphate-mannose-protein mannosyltransferase YP_880378.1 1063664 R 243243 CDS YP_880379.1 118463784 4530135 1065276..1066112 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 1066112 4530135 MAV_1128 Mycobacterium avium 104 hypothetical protein YP_880379.1 1065276 D 243243 CDS YP_880380.1 118463223 4528797 complement(1066109..1067359) 1 NC_008595.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase component I 1067359 pabB 4528797 pabB Mycobacterium avium 104 aminodeoxychorismate synthase component I YP_880380.1 1066109 R 243243 CDS YP_880381.1 118462666 4529094 complement(1067398..1068324) 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; match to protein family HMM TIGR02957; sigma factor 1068324 4529094 MAV_1129 Mycobacterium avium 104 sigma factor YP_880381.1 1067398 R 243243 CDS YP_880382.1 118466873 4526691 complement(1068321..1069493) 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; dehydrogenase 1069493 4526691 MAV_1130 Mycobacterium avium 104 dehydrogenase YP_880382.1 1068321 R 243243 CDS YP_880383.1 118462313 4529631 1069832..1071520 1 NC_008595.1 hypothetical protein 1071520 4529631 MAV_1131 Mycobacterium avium 104 hypothetical protein YP_880383.1 1069832 D 243243 CDS YP_880384.1 118462879 4527485 1071648..1073501 1 NC_008595.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; cyclic diguanylate phosphodiesterase domain-containing protein 1073501 4527485 MAV_1132 Mycobacterium avium 104 cyclic diguanylate phosphodiesterase domain-containing protein YP_880384.1 1071648 D 243243 CDS YP_880385.1 118466325 4528756 complement(1073515..1074309) 1 NC_008595.1 identified by match to protein family HMM TIGR01444; methyltransferase FkbM 1074309 4528756 MAV_1133 Mycobacterium avium 104 methyltransferase FkbM YP_880385.1 1073515 R 243243 CDS YP_880386.1 118465081 4525898 1074519..1076279 1 NC_008595.1 hypothetical protein 1076279 4525898 MAV_1134 Mycobacterium avium 104 hypothetical protein YP_880386.1 1074519 D 243243 CDS YP_880387.1 118465625 4528741 1076462..1077925 1 NC_008595.1 identified by match to protein family HMM PF02706; chain length determinant protein 1077925 4528741 MAV_1135 Mycobacterium avium 104 chain length determinant protein YP_880387.1 1076462 D 243243 CDS YP_880388.1 118463949 4526601 1077922..1079412 1 NC_008595.1 identified by match to protein family HMM PF04932; O-antigen polymerase 1079412 4526601 MAV_1136 Mycobacterium avium 104 O-antigen polymerase YP_880388.1 1077922 D 243243 CDS YP_880389.1 118464535 4530405 1079428..1080441 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 1080441 4530405 MAV_1137 Mycobacterium avium 104 glycosyl transferase, group 1 family protein YP_880389.1 1079428 D 243243 CDS YP_880390.1 118466218 4528897 1081377..1082177 1 NC_008595.1 hypothetical protein 1082177 4528897 MAV_1139 Mycobacterium avium 104 hypothetical protein YP_880390.1 1081377 D 243243 CDS YP_880391.1 118466962 4530274 1082499..1083176 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1083176 4530274 MAV_1140 Mycobacterium avium 104 TetR family transcriptional regulator YP_880391.1 1082499 D 243243 CDS YP_880392.1 118462411 4525721 1083233..1083928 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1083928 4525721 MAV_1141 Mycobacterium avium 104 TetR family transcriptional regulator YP_880392.1 1083233 D 243243 CDS YP_880393.1 118465393 4529685 1086062..1087078 1 NC_008595.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase 1087078 4529685 MAV_1144 Mycobacterium avium 104 polysaccharide deacetylase YP_880393.1 1086062 D 243243 CDS YP_880394.1 118463759 4528003 complement(1087075..1087437) 1 NC_008595.1 identified by match to protein family HMM PF00989; two-component sensor histidine kinase protein, putative 1087437 4528003 MAV_1143 Mycobacterium avium 104 two-component sensor histidine kinase protein, putative YP_880394.1 1087075 R 243243 CDS YP_880395.1 118465949 4527945 complement(1087532..1089091) 1 NC_008595.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1089091 metG 4527945 metG Mycobacterium avium 104 methionyl-tRNA synthetase YP_880395.1 1087532 R 243243 CDS YP_880396.1 118464532 4530402 1089111..1089965 1 NC_008595.1 identified by match to protein family HMM PF01026; match to protein family HMM PF04909; match to protein family HMM TIGR00010; hydrolase, TatD family protein 1089965 4530402 MAV_1146 Mycobacterium avium 104 hydrolase, TatD family protein YP_880396.1 1089111 D 243243 CDS YP_880397.1 118463933 4528113 1090233..1091255 1 NC_008595.1 identified by match to protein family HMM PF03990; match to protein family HMM PF06737; match to protein family HMM PF07501; resuscitation-promoting factor RpfB 1091255 4528113 MAV_1147 Mycobacterium avium 104 resuscitation-promoting factor RpfB YP_880397.1 1090233 D 243243 CDS YP_880398.1 118466314 4528356 1091219..1092175 1 NC_008595.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1092175 ksgA 4528356 ksgA Mycobacterium avium 104 dimethyladenosine transferase YP_880398.1 1091219 D 243243 CDS YP_880399.1 118465699 4530321 1092247..1093197 1 NC_008595.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1093197 ispE 4530321 ispE Mycobacterium avium 104 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_880399.1 1092247 D 243243 CDS YP_880400.1 118465951 4527947 1093557..1095191 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1095191 4527947 MAV_1150 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_880400.1 1093557 D 243243 CDS YP_880401.1 118465371 4529232 complement(1095266..1095841) 1 NC_008595.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1095841 pth 4529232 pth Mycobacterium avium 104 peptidyl-tRNA hydrolase YP_880401.1 1095266 R 243243 CDS YP_880402.1 118464181 4526491 complement(1095854..1096513) 1 NC_008595.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1096513 4526491 MAV_1152 Mycobacterium avium 104 50S ribosomal protein L25 YP_880402.1 1095854 R 243243 CDS YP_880403.1 118463638 4528540 complement(1096650..1097519) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF07993; retinol dehydrogenase 1097519 4528540 MAV_1153 Mycobacterium avium 104 retinol dehydrogenase YP_880403.1 1096650 R 243243 CDS YP_880404.1 118466388 4526189 complement(1097562..1098221) 1 NC_008595.1 LpqT protein 1098221 4526189 MAV_1154 Mycobacterium avium 104 LpqT protein YP_880404.1 1097562 R 243243 CDS YP_880405.1 118466804 4529050 complement(1098218..1098565) 1 NC_008595.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 1098565 arsC 4529050 arsC Mycobacterium avium 104 arsenate reductase YP_880405.1 1098218 R 243243 CDS YP_880406.1 118462677 4530604 complement(1098566..1099546) 1 NC_008595.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1099546 4530604 MAV_1156 Mycobacterium avium 104 ribose-phosphate pyrophosphokinase YP_880406.1 1098566 R 243243 CDS YP_880407.1 118463047 4528326 complement(1099659..1101131) 1 NC_008595.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1101131 glmU 4528326 glmU Mycobacterium avium 104 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_880407.1 1099659 R 243243 CDS YP_880408.1 118463436 4528316 1101423..1102082 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1102082 4528316 MAV_1159 Mycobacterium avium 104 TetR family transcriptional regulator YP_880408.1 1101423 D 243243 CDS YP_880409.1 118464302 4526632 complement(1102159..1103493) 1 NC_008595.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1103493 lysA 4526632 lysA Mycobacterium avium 104 diaminopimelate decarboxylase YP_880409.1 1102159 R 243243 CDS YP_880410.1 118465593 4527141 1107329..1108333 1 NC_008595.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1108333 4527141 MAV_1162 Mycobacterium avium 104 nucleoside triphosphate pyrophosphohydrolase YP_880410.1 1107329 D 243243 CDS YP_880411.1 118465114 4530466 1108638..1109366 1 NC_008595.1 LpqU protein 1109366 4530466 MAV_1163 Mycobacterium avium 104 LpqU protein YP_880411.1 1108638 D 243243 CDS YP_880412.1 118466789 4529347 1109424..1110713 1 NC_008595.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1110713 eno 4529347 eno Mycobacterium avium 104 phosphopyruvate hydratase YP_880412.1 1109424 D 243243 CDS YP_880413.1 118466167 4528790 1110715..1111392 1 NC_008595.1 identified by match to protein family HMM PF04977; septum formation initiator subfamily protein, putative 1111392 4528790 MAV_1165 Mycobacterium avium 104 septum formation initiator subfamily protein, putative YP_880413.1 1110715 D 243243 CDS YP_880414.1 118465889 4527923 1111445..1111873 1 NC_008595.1 identified by match to protein family HMM PF04417; hypothetical protein 1111873 4527923 MAV_1166 Mycobacterium avium 104 hypothetical protein YP_880414.1 1111445 D 243243 CDS YP_880415.1 118465203 4530400 1111870..1112817 1 NC_008595.1 identified by match to protein family HMM PF02541; exopolyphosphatase 1112817 4530400 MAV_1167 Mycobacterium avium 104 exopolyphosphatase YP_880415.1 1111870 D 243243 CDS YP_880416.1 118467243 4529800 1113029..1113355 1 NC_008595.1 hypothetical protein 1113355 4529800 MAV_1168 Mycobacterium avium 104 hypothetical protein YP_880416.1 1113029 D 243243 CDS YP_880417.1 118466690 4530432 complement(1113443..1114123) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; KDP operon transcriptional regulator KdpE 1114123 4530432 MAV_1169 Mycobacterium avium 104 KDP operon transcriptional regulator KdpE YP_880417.1 1113443 R 243243 CDS YP_880418.1 118464374 4530517 complement(1114173..1116737) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702; sensor protein KdpD 1116737 4530517 MAV_1170 Mycobacterium avium 104 sensor protein KdpD YP_880418.1 1114173 R 243243 CDS YP_880419.1 118462407 4525717 complement(1116762..1117637) 1 NC_008595.1 identified by match to protein family HMM PF02669; K+-transporting ATPase, C subunit 1117637 kdpC 4525717 kdpC Mycobacterium avium 104 K+-transporting ATPase, C subunit YP_880419.1 1116762 R 243243 CDS YP_880420.1 118463128 4529653 complement(1117639..1119789) 1 NC_008595.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 1119789 kdpB 4529653 kdpB Mycobacterium avium 104 potassium-transporting ATPase subunit B YP_880420.1 1117639 R 243243 CDS YP_880421.1 118466520 4527193 complement(1119789..1121459) 1 NC_008595.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 1121459 kdpA 4527193 kdpA Mycobacterium avium 104 potassium-transporting ATPase subunit A YP_880421.1 1119789 R 243243 CDS YP_880422.1 118467027 4526539 complement(1121546..1121629) 1 NC_008595.1 potassium-transporting ATPase, F subunit, putative 1121629 4526539 MAV_1174 Mycobacterium avium 104 potassium-transporting ATPase, F subunit, putative YP_880422.1 1121546 R 243243 CDS YP_880423.1 118463007 4526299 complement(1121820..1123358) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; two component sensor histidine kinase trcs 1123358 4526299 MAV_1175 Mycobacterium avium 104 two component sensor histidine kinase trcs YP_880423.1 1121820 R 243243 CDS YP_880424.1 118466262 4526881 complement(1123355..1124119) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; TrcR family transcriptional regulator 1124119 4526881 MAV_1176 Mycobacterium avium 104 TrcR family transcriptional regulator YP_880424.1 1123355 R 243243 CDS YP_880425.1 118466478 4527608 complement(1124339..1124623) 1 NC_008595.1 identified by match to protein family HMM PF06359; hypothetical protein 1124623 4527608 MAV_1177 Mycobacterium avium 104 hypothetical protein YP_880425.1 1124339 R 243243 CDS YP_880426.1 118467092 4526392 complement(1124666..1124962) 1 NC_008595.1 identified by match to protein family HMM PF06013; hypothetical protein 1124962 4526392 MAV_1178 Mycobacterium avium 104 hypothetical protein YP_880426.1 1124666 R 243243 CDS YP_880427.1 118464572 4530276 1127854..1129065 1 NC_008595.1 hypothetical protein 1129065 4530276 MAV_1181 Mycobacterium avium 104 hypothetical protein YP_880427.1 1127854 D 243243 CDS YP_880428.1 118465039 4525818 1129130..1129927 1 NC_008595.1 hypothetical protein 1129927 4525818 MAV_1182 Mycobacterium avium 104 hypothetical protein YP_880428.1 1129130 D 243243 CDS YP_880429.1 118466322 4528753 1129937..1130095 1 NC_008595.1 hypothetical protein 1130095 4528753 MAV_1183 Mycobacterium avium 104 hypothetical protein YP_880429.1 1129937 D 243243 CDS YP_880430.1 118465664 4526736 1130104..1130874 1 NC_008595.1 identified by match to protein family HMM PF04248; hypothetical protein 1130874 4526736 MAV_1184 Mycobacterium avium 104 hypothetical protein YP_880430.1 1130104 D 243243 CDS YP_880431.1 118466241 4526587 1131175..1132362 1 NC_008595.1 identified by match to protein family HMM TIGR02276; hypothetical protein 1132362 4526587 MAV_1185 Mycobacterium avium 104 hypothetical protein YP_880431.1 1131175 D 243243 CDS YP_880432.1 118466790 4529348 1132524..1134155 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1134155 4529348 MAV_1186 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_880432.1 1132524 D 243243 CDS YP_880433.1 118465043 4525822 1134169..1134642 1 NC_008595.1 hypothetical protein 1134642 4525822 MAV_1187 Mycobacterium avium 104 hypothetical protein YP_880433.1 1134169 D 243243 CDS YP_880434.1 118465606 4527865 1134671..1135558 1 NC_008595.1 identified by match to protein family HMM PF00310; glutamine amidotransferase, class-II 1135558 4527865 MAV_1188 Mycobacterium avium 104 glutamine amidotransferase, class-II YP_880434.1 1134671 D 243243 CDS YP_880435.1 118466234 4526580 1135583..1136452 1 NC_008595.1 identified by match to protein family HMM PF01734; phospholipase, patatin family protein 1136452 4526580 MAV_1189 Mycobacterium avium 104 phospholipase, patatin family protein YP_880435.1 1135583 D 243243 CDS YP_880436.1 118466727 4530665 complement(1136478..1137515) 1 NC_008595.1 identified by match to protein family HMM PF01734; patatin 1137515 4530665 MAV_1190 Mycobacterium avium 104 patatin YP_880436.1 1136478 R 243243 CDS YP_880437.1 118467266 4527068 complement(1137684..1138091) 1 NC_008595.1 LpqV protein 1138091 4527068 MAV_1191 Mycobacterium avium 104 LpqV protein YP_880437.1 1137684 R 243243 CDS YP_880438.1 118463236 4525772 1138255..1138848 1 NC_008595.1 identified by match to protein family HMM PF05995; cysteine dioxygenase type I superfamily protein 1138848 4525772 MAV_1192 Mycobacterium avium 104 cysteine dioxygenase type I superfamily protein YP_880438.1 1138255 D 243243 CDS YP_880439.1 118463969 4527215 1138848..1139285 1 NC_008595.1 hypothetical protein 1139285 4527215 MAV_1194 Mycobacterium avium 104 hypothetical protein YP_880439.1 1138848 D 243243 CDS YP_880440.1 118465570 4526756 complement(1139282..1141066) 1 NC_008595.1 hypothetical protein 1141066 4526756 MAV_1193 Mycobacterium avium 104 hypothetical protein YP_880440.1 1139282 R 243243 CDS YP_880441.1 118466122 4529755 complement(1141076..1141867) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1141867 4529755 MAV_1195 Mycobacterium avium 104 enoyl-CoA hydratase YP_880441.1 1141076 R 243243 CDS YP_880442.1 118467061 4526439 complement(1141881..1142918) 1 NC_008595.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 1142918 4526439 MAV_1196 Mycobacterium avium 104 3-hydroxyisobutyryl-CoA hydrolase YP_880442.1 1141881 R 243243 CDS YP_880443.1 118462485 4530681 1143217..1143984 1 NC_008595.1 identified by match to protein family HMM PF06539; permease of the major facilitator superfamily protein 1143984 4530681 MAV_1197 Mycobacterium avium 104 permease of the major facilitator superfamily protein YP_880443.1 1143217 D 243243 CDS YP_880444.1 118462688 4530616 complement(1144188..1145405) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1145405 4530616 MAV_1198 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880444.1 1144188 R 243243 CDS YP_880445.1 118463165 4529866 complement(1145496..1146470) 1 NC_008595.1 identified by match to protein family HMM PF00657; hypothetical protein 1146470 4529866 MAV_1199 Mycobacterium avium 104 hypothetical protein YP_880445.1 1145496 R 243243 CDS YP_880446.1 118464779 4529134 1146702..1147766 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 1147766 4529134 MAV_1200 Mycobacterium avium 104 alpha/beta hydrolase YP_880446.1 1146702 D 243243 CDS YP_880447.1 118464016 4528812 1147809..1149215 1 NC_008595.1 identified by match to protein family HMM PF00291; match to protein family HMM PF00571; match to protein family HMM TIGR01137; cystathionine beta-synthase 1149215 4528812 MAV_1201 Mycobacterium avium 104 cystathionine beta-synthase YP_880447.1 1147809 D 243243 CDS YP_880448.1 118463979 4530337 1149306..1150025 1 NC_008595.1 identified by match to protein family HMM PF06271; Pra protein 1150025 4530337 MAV_1202 Mycobacterium avium 104 Pra protein YP_880448.1 1149306 D 243243 CDS YP_880449.1 118463216 4527543 1150063..1151229 1 NC_008595.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1151229 4527543 MAV_1203 Mycobacterium avium 104 cystathionine gamma-synthase YP_880449.1 1150063 D 243243 CDS YP_880450.1 118462687 4530615 complement(1151248..1151727) 1 NC_008595.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1151727 greA 4530615 greA Mycobacterium avium 104 transcription elongation factor GreA YP_880450.1 1151248 R 243243 CDS YP_880451.1 118466315 4528357 complement(1151963..1152388) 1 NC_008595.1 hypothetical protein 1152388 4528357 MAV_1205 Mycobacterium avium 104 hypothetical protein YP_880451.1 1151963 R 243243 CDS YP_880452.1 118464969 4528709 1152499..1153371 1 NC_008595.1 identified by match to protein family HMM PF02585; mycothiol conjugate amidase Mca 1153371 4528709 MAV_1206 Mycobacterium avium 104 mycothiol conjugate amidase Mca YP_880452.1 1152499 D 243243 CDS YP_880453.1 118464212 4526892 1153368..1153688 1 NC_008595.1 hypothetical protein 1153688 4526892 MAV_1207 Mycobacterium avium 104 hypothetical protein YP_880453.1 1153368 D 243243 CDS YP_880454.1 118464036 4529008 1153675..1155690 1 NC_008595.1 identified by match to protein family HMM PF03190; hypothetical protein 1155690 4529008 MAV_1208 Mycobacterium avium 104 hypothetical protein YP_880454.1 1153675 D 243243 CDS YP_880455.1 118463276 4530524 1155712..1156095 1 NC_008595.1 identified by match to protein family HMM PF02136; steroid delta-isomerase 1156095 4530524 MAV_1209 Mycobacterium avium 104 steroid delta-isomerase YP_880455.1 1155712 D 243243 CDS YP_880456.1 118464088 4528401 complement(1156105..1156878) 1 NC_008595.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; channel protein, hemolysin III family protein 1156878 4528401 MAV_1210 Mycobacterium avium 104 channel protein, hemolysin III family protein YP_880456.1 1156105 R 243243 CDS YP_880457.1 118463939 4526591 1157051..1157845 1 NC_008595.1 identified by match to protein family HMM PF01255; match to protein family HMM TIGR00055; short chain Z-isoprenyl diphosphate synthetase 1157845 4526591 MAV_1211 Mycobacterium avium 104 short chain Z-isoprenyl diphosphate synthetase YP_880457.1 1157051 D 243243 CDS YP_880458.1 118464422 4530243 1157900..1159270 1 NC_008595.1 hypothetical protein 1159270 4530243 MAV_1212 Mycobacterium avium 104 hypothetical protein YP_880458.1 1157900 D 243243 CDS YP_880459.1 118466795 4529353 1159517..1159942 1 NC_008595.1 hypothetical protein 1159942 4529353 MAV_1213 Mycobacterium avium 104 hypothetical protein YP_880459.1 1159517 D 243243 CDS YP_880460.1 118465108 4529999 complement(1159962..1160870) 1 NC_008595.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1160870 coaA 4529999 coaA Mycobacterium avium 104 pantothenate kinase YP_880460.1 1159962 R 243243 CDS YP_880461.1 118465701 4530323 1160977..1162308 1 NC_008595.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1162308 glyA 4530323 glyA Mycobacterium avium 104 serine hydroxymethyltransferase YP_880461.1 1160977 D 243243 CDS YP_880462.1 118463991 4530350 1162396..1163223 1 NC_008595.1 identified by match to protein family HMM PF03405; Fatty acid desaturase 1163223 4530350 MAV_1216 Mycobacterium avium 104 Fatty acid desaturase YP_880462.1 1162396 D 243243 CDS YP_880463.1 118464561 4530780 1163443..1164744 1 NC_008595.1 identified by match to protein family HMM PF02562; PhoH2 protein 1164744 4530780 MAV_1217 Mycobacterium avium 104 PhoH2 protein YP_880463.1 1163443 D 243243 CDS YP_880464.1 118463310 4529550 1164872..1165747 1 NC_008595.1 identified by match to protein family HMM PF01522; carbohydrate degrading enzyme 1165747 4529550 MAV_1218 Mycobacterium avium 104 carbohydrate degrading enzyme YP_880464.1 1164872 D 243243 CDS YP_880465.1 118466455 4528676 1165812..1167245 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF00672; adenylate cyclase, family protein 3 1167245 4528676 MAV_1220 Mycobacterium avium 104 adenylate cyclase, family protein 3 YP_880465.1 1165812 D 243243 CDS YP_880466.1 118466854 4529806 complement(1167242..1168261) 1 NC_008595.1 hypothetical protein 1168261 4529806 MAV_1219 Mycobacterium avium 104 hypothetical protein YP_880466.1 1167242 R 243243 CDS YP_880467.1 118465356 4526669 complement(1168310..1169722) 1 NC_008595.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1169722 fumC 4526669 fumC Mycobacterium avium 104 fumarate hydratase YP_880467.1 1168310 R 243243 CDS YP_880468.1 118465743 4525706 complement(1169753..1170832) 1 NC_008595.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 1170832 glpX 4525706 glpX Mycobacterium avium 104 fructose 1,6-bisphosphatase II YP_880468.1 1169753 R 243243 CDS YP_880469.1 118463584 4529769 1170888..1171574 1 NC_008595.1 hypothetical protein 1171574 4529769 MAV_1223 Mycobacterium avium 104 hypothetical protein YP_880469.1 1170888 D 243243 CDS YP_880470.1 118463015 4526308 1171588..1172391 1 NC_008595.1 dienelactone hydrolase 1172391 4526308 MAV_1224 Mycobacterium avium 104 dienelactone hydrolase YP_880470.1 1171588 D 243243 CDS YP_880471.1 118466198 4530188 1172473..1174017 1 NC_008595.1 identified by match to protein family HMM PF00135; carboxylesterase 1174017 4530188 MAV_1226 Mycobacterium avium 104 carboxylesterase YP_880471.1 1172473 D 243243 CDS YP_880472.1 118466413 4526256 complement(1174014..1175114) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; 3-beta hydroxysteroid dehydrogenase/isomerase 1175114 4526256 MAV_1225 Mycobacterium avium 104 3-beta hydroxysteroid dehydrogenase/isomerase YP_880472.1 1174014 R 243243 CDS YP_880473.1 118465063 4527039 complement(1175176..1175424) 1 NC_008595.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1175424 xseB 4527039 xseB Mycobacterium avium 104 exodeoxyribonuclease VII small subunit YP_880473.1 1175176 R 243243 CDS YP_880474.1 118462521 4527664 complement(1175414..1176553) 1 NC_008595.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1176553 xseA 4527664 xseA Mycobacterium avium 104 exodeoxyribonuclease VII large subunit YP_880474.1 1175414 R 243243 CDS YP_880475.1 118463104 4527166 complement(1176658..1177254) 1 NC_008595.1 hypothetical protein 1177254 4527166 MAV_1229 Mycobacterium avium 104 hypothetical protein YP_880475.1 1176658 R 243243 CDS YP_880476.1 118464410 4530804 1177452..1178342 1 NC_008595.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1178342 ispH 4530804 ispH Mycobacterium avium 104 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_880476.1 1177452 D 243243 CDS YP_880477.1 118462991 4530621 complement(1178359..1179465) 1 NC_008595.1 hypothetical protein 1179465 4530621 MAV_1231 Mycobacterium avium 104 hypothetical protein YP_880477.1 1178359 R 243243 CDS YP_880478.1 118462264 4526408 1179704..1180756 1 NC_008595.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1180756 ychF 4526408 ychF Mycobacterium avium 104 GTP-dependent nucleic acid-binding protein EngD YP_880478.1 1179704 D 243243 CDS YP_880479.1 118465288 4529324 1180947..1181222 1 NC_008595.1 transposase 1181222 4529324 MAV_1233 Mycobacterium avium 104 transposase YP_880479.1 1180947 D 243243 CDS YP_880480.1 118466328 4528759 1182242..1183516 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1183516 4528759 MAV_1235 Mycobacterium avium 104 transposase, Mutator family protein YP_880480.1 1182242 D 243243 CDS YP_880481.1 118465054 4527030 1183823..1184032 1 NC_008595.1 identified by match to protein family HMM PF01844; HNH endonuclease, putative 1184032 4527030 MAV_1236 Mycobacterium avium 104 HNH endonuclease, putative YP_880481.1 1183823 D 243243 CDS YP_880482.1 118465269 4527290 complement(1184295..1185599) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1185599 4527290 MAV_1237 Mycobacterium avium 104 transposase, Mutator family protein YP_880482.1 1184295 R 243243 CDS YP_880483.1 118463251 4525787 complement(1185708..1186970) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1186970 4525787 MAV_1238 Mycobacterium avium 104 transposase, Mutator family protein YP_880483.1 1185708 R 243243 CDS YP_880484.1 118465443 4527312 1187107..1187313 1 NC_008595.1 identified by similarity to RF:ZP_00993826.1; hypothetical protein 1187313 4527312 MAV_1239 Mycobacterium avium 104 hypothetical protein YP_880484.1 1187107 D 243243 CDS YP_880485.1 118464152 4526461 1187300..1187671 1 NC_008595.1 identified by match to protein family HMM PF01850; PilT domain-containing protein 1187671 4526461 MAV_1240 Mycobacterium avium 104 PilT domain-containing protein YP_880485.1 1187300 D 243243 CDS YP_880486.1 118462620 4526422 1187804..1188211 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 1188211 4526422 MAV_1241 Mycobacterium avium 104 hypothetical protein YP_880486.1 1187804 D 243243 CDS YP_880487.1 118463290 4530538 complement(1188277..1189014) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 1189014 4530538 MAV_1242 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_880487.1 1188277 R 243243 CDS YP_880488.1 118466289 4529535 1189110..1189715 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 1189715 4529535 MAV_1243 Mycobacterium avium 104 transcriptional regulator YP_880488.1 1189110 D 243243 CDS YP_880489.1 118466928 4527763 1189817..1190215 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 1190215 4527763 MAV_1244 Mycobacterium avium 104 glyoxalase YP_880489.1 1189817 D 243243 CDS YP_880490.1 118464215 4526895 1190284..1190667 1 NC_008595.1 secreted protein antigen 1190667 4526895 MAV_1245 Mycobacterium avium 104 secreted protein antigen YP_880490.1 1190284 D 243243 CDS YP_880491.1 118467037 4526551 1190737..1191069 1 NC_008595.1 hypothetical protein 1191069 4526551 MAV_1246 Mycobacterium avium 104 hypothetical protein YP_880491.1 1190737 D 243243 CDS YP_880492.1 118463636 4528538 1191364..1191774 1 NC_008595.1 hypothetical protein 1191774 4528538 MAV_1247 Mycobacterium avium 104 hypothetical protein YP_880492.1 1191364 D 243243 CDS YP_880493.1 118463040 4528881 1192185..1192508 1 NC_008595.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase 1192508 4528881 MAV_1248 Mycobacterium avium 104 antibiotic biosynthesis monooxygenase YP_880493.1 1192185 D 243243 CDS YP_880494.1 118465400 4525660 complement(1192513..1193196) 1 NC_008595.1 hypothetical protein 1193196 4525660 MAV_1249 Mycobacterium avium 104 hypothetical protein YP_880494.1 1192513 R 243243 CDS YP_880495.1 118462352 4527979 1193323..1193511 1 NC_008595.1 hypothetical protein 1193511 4527979 MAV_1251 Mycobacterium avium 104 hypothetical protein YP_880495.1 1193323 D 243243 CDS YP_880496.1 118464216 4526896 complement(1193469..1194287) 1 NC_008595.1 identified by match to protein family HMM PF00211; adenylate and guanylate cyclase catalytic domain-containing protein 1194287 4526896 MAV_1250 Mycobacterium avium 104 adenylate and guanylate cyclase catalytic domain-containing protein YP_880496.1 1193469 R 243243 CDS YP_880497.1 118465997 4526139 1194419..1195828 1 NC_008595.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1195828 zwf 4526139 zwf Mycobacterium avium 104 glucose-6-phosphate 1-dehydrogenase YP_880497.1 1194419 D 243243 CDS YP_880498.1 118465415 4529964 1195845..1196867 1 NC_008595.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 1196867 gnd 4529964 gnd Mycobacterium avium 104 6-phosphogluconate dehydrogenase YP_880498.1 1195845 D 243243 CDS YP_880499.1 118466531 4526999 complement(1196881..1197714) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1197714 4526999 MAV_1254 Mycobacterium avium 104 alpha/beta hydrolase YP_880499.1 1196881 R 243243 CDS YP_880500.1 118466351 4530491 1197866..1198339 1 NC_008595.1 identified by match to protein family HMM PF06983; 3-demethylubiquinone-9 3-methyltransferase 1198339 4530491 MAV_1255 Mycobacterium avium 104 3-demethylubiquinone-9 3-methyltransferase YP_880500.1 1197866 D 243243 CDS YP_880501.1 118463164 4529865 1198445..1199359 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1199359 4529865 MAV_1256 Mycobacterium avium 104 alpha/beta hydrolase YP_880501.1 1198445 D 243243 CDS YP_880502.1 118466899 4528413 1199375..1200601 1 NC_008595.1 identified by match to protein family HMM PF03007; hypothetical protein 1200601 4528413 MAV_1257 Mycobacterium avium 104 hypothetical protein YP_880502.1 1199375 D 243243 CDS YP_880503.1 118463406 4530043 complement(1200602..1201207) 1 NC_008595.1 hypothetical protein 1201207 4530043 MAV_1258 Mycobacterium avium 104 hypothetical protein YP_880503.1 1200602 R 243243 CDS YP_880504.1 118464109 4526280 complement(1201204..1202769) 1 NC_008595.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1202769 4526280 MAV_1259 Mycobacterium avium 104 pyruvate phosphate dikinase YP_880504.1 1201204 R 243243 CDS YP_880505.1 118464924 4528564 1202986..1203495 1 NC_008595.1 identified by match to protein family HMM PF07681; DoxX subfamily protein, putative 1203495 4528564 MAV_1260 Mycobacterium avium 104 DoxX subfamily protein, putative YP_880505.1 1202986 D 243243 CDS YP_880506.1 118464709 4529396 1203664..1205412 1 NC_008595.1 hypothetical protein 1205412 4529396 MAV_1261 Mycobacterium avium 104 hypothetical protein YP_880506.1 1203664 D 243243 CDS YP_880507.1 118463901 4525831 complement(1205460..1207730) 1 NC_008595.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1207730 metE 4525831 metE Mycobacterium avium 104 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_880507.1 1205460 R 243243 CDS YP_880508.1 118466116 4529749 complement(1208176..1208805) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 1208805 4529749 MAV_1263 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_880508.1 1208176 R 243243 CDS YP_880509.1 118462808 4529028 complement(1208843..1209685) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 1209685 4529028 MAV_1264 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_880509.1 1208843 R 243243 CDS YP_880510.1 118462674 4530601 complement(1209788..1211077) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1211077 4530601 MAV_1265 Mycobacterium avium 104 TetR family transcriptional regulator YP_880510.1 1209788 R 243243 CDS YP_880511.1 118463238 4525774 complement(1211216..1211863) 1 NC_008595.1 identified by match to protein family HMM PF00881; nitroreductase 1211863 4525774 MAV_1266 Mycobacterium avium 104 nitroreductase YP_880511.1 1211216 R 243243 CDS YP_880512.1 118462686 4530614 complement(1211863..1212963) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 1212963 4530614 MAV_1267 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880512.1 1211863 R 243243 CDS YP_880513.1 118464702 4527891 complement(1212960..1214129) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase domain-containing protein 1214129 4527891 MAV_1268 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880513.1 1212960 R 243243 CDS YP_880514.1 118464083 4528396 1214341..1216056 1 NC_008595.1 identified by match to protein family HMM PF00092; von Willebrand factor type A 1216056 4528396 MAV_1269 Mycobacterium avium 104 von Willebrand factor type A YP_880514.1 1214341 D 243243 CDS YP_880515.1 118464895 4529624 1216070..1216912 1 NC_008595.1 identified by match to protein family HMM PF07728; denitrification regulatory protein nirQ 1216912 4529624 MAV_1270 Mycobacterium avium 104 denitrification regulatory protein nirQ YP_880515.1 1216070 D 243243 CDS YP_880516.1 118466867 4529819 1216995..1218113 1 NC_008595.1 hypothetical protein 1218113 4529819 MAV_1271 Mycobacterium avium 104 hypothetical protein YP_880516.1 1216995 D 243243 CDS YP_880517.1 118466282 4527835 1218118..1219263 1 NC_008595.1 hypothetical protein 1219263 4527835 MAV_1272 Mycobacterium avium 104 hypothetical protein YP_880517.1 1218118 D 243243 CDS YP_880518.1 118464877 4530713 1219256..1220281 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 1220281 4530713 MAV_1273 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_880518.1 1219256 D 243243 CDS YP_880519.1 118465436 4527305 1220284..1221498 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1221498 4527305 MAV_1274 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880519.1 1220284 D 243243 CDS YP_880520.1 118467260 4526095 1221625..1223073 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1223073 4526095 MAV_1275 Mycobacterium avium 104 aldehyde dehydrogenase YP_880520.1 1221625 D 243243 CDS YP_880521.1 118466226 4526572 1223530..1224678 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 1224678 4526572 MAV_1276 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880521.1 1223530 D 243243 CDS YP_880522.1 118462923 4526014 1224675..1225466 1 NC_008595.1 identified by match to protein family HMM PF00378; carnitinyl-CoA dehydratase 1225466 4526014 MAV_1277 Mycobacterium avium 104 carnitinyl-CoA dehydratase YP_880522.1 1224675 D 243243 CDS YP_880523.1 118462501 4528579 complement(1225476..1226489) 1 NC_008595.1 identified by match to protein family HMM PF01494; oxidoreductase 1226489 4528579 MAV_1278 Mycobacterium avium 104 oxidoreductase YP_880523.1 1225476 R 243243 CDS YP_880524.1 118464098 4525859 complement(1226539..1227039) 1 NC_008595.1 identified by match to protein family HMM PF04140; isoprenylcysteine carboxyl methyltransferase (icmt) family protein 1227039 4525859 MAV_1279 Mycobacterium avium 104 isoprenylcysteine carboxyl methyltransferase (icmt) family protein YP_880524.1 1226539 R 243243 CDS YP_880525.1 118463211 4527538 complement(1227060..1228109) 1 NC_008595.1 identified by match to protein family HMM PF00195; match to protein family HMM PF02797; transferase 1228109 4527538 MAV_1280 Mycobacterium avium 104 transferase YP_880525.1 1227060 R 243243 CDS YP_880526.1 118466207 4528886 1228395..1229543 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; hypothetical protein 1229543 4528886 MAV_1281 Mycobacterium avium 104 hypothetical protein YP_880526.1 1228395 D 243243 CDS YP_880527.1 118465649 4526174 1229540..1230262 1 NC_008595.1 identified by match to protein family HMM PF02517; caax amino protease 1230262 4526174 MAV_1282 Mycobacterium avium 104 caax amino protease YP_880527.1 1229540 D 243243 CDS YP_880528.1 118462545 4530546 complement(1230296..1231108) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1231108 4530546 MAV_1283 Mycobacterium avium 104 enoyl-CoA hydratase YP_880528.1 1230296 R 243243 CDS YP_880529.1 118462940 4530225 1231228..1232310 1 NC_008595.1 identified by match to protein family HMM PF02515; Mcr protein 1232310 4530225 MAV_1284 Mycobacterium avium 104 Mcr protein YP_880529.1 1231228 D 243243 CDS YP_880530.1 118465282 4529318 1232373..1233137 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 3-hydroxyacyl-CoA dehydrogenase 1233137 4529318 MAV_1285 Mycobacterium avium 104 3-hydroxyacyl-CoA dehydrogenase YP_880530.1 1232373 D 243243 CDS YP_880531.1 118465797 4526110 complement(1233273..1233395) 1 NC_008595.1 hypothetical protein 1233395 4526110 MAV_1286 Mycobacterium avium 104 hypothetical protein YP_880531.1 1233273 R 243243 CDS YP_880532.1 118466696 4530438 1233708..1236134 1 NC_008595.1 mmpL protein 1236134 4530438 MAV_1287 Mycobacterium avium 104 mmpL protein YP_880532.1 1233708 D 243243 CDS YP_880533.1 118467251 4526086 1236131..1236766 1 NC_008595.1 hypothetical protein 1236766 4526086 MAV_1288 Mycobacterium avium 104 hypothetical protein YP_880533.1 1236131 D 243243 CDS YP_880534.1 118462911 4528174 complement(1236774..1237475) 1 NC_008595.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1237475 4528174 MAV_1289 Mycobacterium avium 104 NAD-dependent deacetylase YP_880534.1 1236774 R 243243 CDS YP_880535.1 118466127 4529760 1237525..1237890 1 NC_008595.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1237890 4529760 MAV_1290 Mycobacterium avium 104 GntR family transcriptional regulator YP_880535.1 1237525 D 243243 CDS YP_880536.1 118464291 4529579 complement(1237942..1238502) 1 NC_008595.1 identified by match to protein family HMM PF08002; hypothetical protein 1238502 4529579 MAV_1291 Mycobacterium avium 104 hypothetical protein YP_880536.1 1237942 R 243243 CDS YP_880537.1 118462449 4525622 1238541..1238984 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 1238984 4525622 MAV_1292 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_880537.1 1238541 D 243243 CDS YP_880538.1 118462369 4529181 1239043..1239267 1 NC_008595.1 hypothetical protein 1239267 4529181 MAV_1293 Mycobacterium avium 104 hypothetical protein YP_880538.1 1239043 D 243243 CDS YP_880539.1 118466984 4529511 1239429..1240004 1 NC_008595.1 identified by match to protein family HMM PF00730; base excision DNA repair protein, HhH-GPD family protein 1240004 4529511 MAV_1294 Mycobacterium avium 104 base excision DNA repair protein, HhH-GPD family protein YP_880539.1 1239429 D 243243 CDS YP_880540.1 118462834 4528648 1240033..1240179 1 NC_008595.1 hypothetical protein 1240179 4528648 MAV_1295 Mycobacterium avium 104 hypothetical protein YP_880540.1 1240033 D 243243 CDS YP_880541.1 118463381 4528959 complement(1240243..1241322) 1 NC_008595.1 hypothetical protein 1241322 4528959 MAV_1296 Mycobacterium avium 104 hypothetical protein YP_880541.1 1240243 R 243243 CDS YP_880542.1 118465711 4530333 complement(1241370..1241960) 1 NC_008595.1 hypothetical protein 1241960 4530333 MAV_1297 Mycobacterium avium 104 hypothetical protein YP_880542.1 1241370 R 243243 CDS YP_880543.1 118463568 4530723 1242335..1243519 1 NC_008595.1 involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis; mannosyltransferase 1243519 pimE 4530723 pimE Mycobacterium avium 104 mannosyltransferase YP_880543.1 1242335 D 243243 CDS YP_880544.1 118465216 4529853 complement(1243582..1243866) 1 NC_008595.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 1243866 phhB 4529853 phhB Mycobacterium avium 104 pterin-4-alpha-carbinolamine dehydratase YP_880544.1 1243582 R 243243 CDS YP_880545.1 118465991 4526133 complement(1243997..1244770) 1 NC_008595.1 hypothetical protein 1244770 4526133 MAV_1300 Mycobacterium avium 104 hypothetical protein YP_880545.1 1243997 R 243243 CDS YP_880546.1 118465401 4525661 1244910..1245332 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, NUDIX family protein 1245332 4525661 MAV_1301 Mycobacterium avium 104 hydrolase, NUDIX family protein YP_880546.1 1244910 D 243243 CDS YP_880547.1 118465204 4530401 complement(1245544..1245768) 1 NC_008595.1 hypothetical protein 1245768 4530401 MAV_1302 Mycobacterium avium 104 hypothetical protein YP_880547.1 1245544 R 243243 CDS YP_880548.1 118462465 4528719 1245751..1249443 1 NC_008595.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase, alpha subunit 1249443 4528719 MAV_1303 Mycobacterium avium 104 nitrate reductase, alpha subunit YP_880548.1 1245751 D 243243 CDS YP_880549.1 118466032 4529919 1249445..1251061 1 NC_008595.1 identified by match to protein family HMM TIGR01660; nitrate reductase, beta subunit 1251061 narH 4529919 narH Mycobacterium avium 104 nitrate reductase, beta subunit YP_880549.1 1249445 D 243243 CDS YP_880550.1 118464247 4527432 1251058..1251741 1 NC_008595.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 1251741 narJ 4527432 narJ Mycobacterium avium 104 nitrate reductase molybdenum cofactor assembly chaperone YP_880550.1 1251058 D 243243 CDS YP_880551.1 118462534 4527677 1251734..1252465 1 NC_008595.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase, gamma subunit 1252465 narI 4527677 narI Mycobacterium avium 104 respiratory nitrate reductase, gamma subunit YP_880551.1 1251734 D 243243 CDS YP_880552.1 118466440 4527113 1252636..1254525 1 NC_008595.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA/BipA 1254525 typA 4527113 typA Mycobacterium avium 104 GTP-binding protein TypA/BipA YP_880552.1 1252636 D 243243 CDS YP_880553.1 118467073 4526451 1254533..1256476 1 NC_008595.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein, family protein 5 1256476 4526451 MAV_1308 Mycobacterium avium 104 extracellular solute-binding protein, family protein 5 YP_880553.1 1254533 D 243243 CDS YP_880554.1 118467207 4529588 complement(1256477..1257169) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1257169 4529588 MAV_1309 Mycobacterium avium 104 TetR family transcriptional regulator YP_880554.1 1256477 R 243243 CDS YP_880555.1 118465188 4530385 1257168..1258070 1 NC_008595.1 identified by match to protein family HMM PF02585; N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB 1258070 4530385 MAV_1310 Mycobacterium avium 104 N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB YP_880555.1 1257168 D 243243 CDS YP_880556.1 118463602 4527549 1258163..1258624 1 NC_008595.1 hypothetical protein 1258624 4527549 MAV_1311 Mycobacterium avium 104 hypothetical protein YP_880556.1 1258163 D 243243 CDS YP_880557.1 118463203 4527530 1258777..1261380 1 NC_008595.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase 1261380 fbiC 4527530 fbiC Mycobacterium avium 104 FO synthase YP_880557.1 1258777 D 243243 CDS YP_880558.1 118467004 4529474 1261420..1262193 1 NC_008595.1 hypothetical protein 1262193 4529474 MAV_1313 Mycobacterium avium 104 hypothetical protein YP_880558.1 1261420 D 243243 CDS YP_880559.1 118465162 4529252 complement(1262218..1262550) 1 NC_008595.1 hypothetical protein 1262550 4529252 MAV_1314 Mycobacterium avium 104 hypothetical protein YP_880559.1 1262218 R 243243 CDS YP_880560.1 118465769 4526904 1262652..1262777 1 NC_008595.1 hypothetical protein 1262777 4526904 MAV_1315 Mycobacterium avium 104 hypothetical protein YP_880560.1 1262652 D 243243 CDS YP_880561.1 118465894 4527928 1262943..1263269 1 NC_008595.1 identified by match to protein family HMM PF00037; ferredoxin 1263269 4527928 MAV_1316 Mycobacterium avium 104 ferredoxin YP_880561.1 1262943 D 243243 CDS YP_880562.1 118464408 4530802 1263278..1264396 1 NC_008595.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 1264396 4530802 MAV_1317 Mycobacterium avium 104 N-succinyldiaminopimelate aminotransferase YP_880562.1 1263278 D 243243 CDS YP_880563.1 118462228 4525565 1264478..1266862 1 NC_008595.1 identified by match to protein family HMM PF01336; OB-fold nucleic acid binding domain-containing protein 1266862 4525565 MAV_1318 Mycobacterium avium 104 OB-fold nucleic acid binding domain-containing protein YP_880563.1 1264478 D 243243 CDS YP_880564.1 118466637 4526993 complement(1266978..1267211) 1 NC_008595.1 hypothetical protein 1267211 4526993 MAV_1319 Mycobacterium avium 104 hypothetical protein YP_880564.1 1266978 R 243243 CDS YP_880565.1 118462928 4526019 1267227..1273496 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; mycocerosic acid synthase 1273496 4526019 MAV_1321 Mycobacterium avium 104 mycocerosic acid synthase YP_880565.1 1267227 D 243243 CDS YP_880566.1 118466505 4525588 complement(1273493..1273738) 1 NC_008595.1 hypothetical protein 1273738 4525588 MAV_1320 Mycobacterium avium 104 hypothetical protein YP_880566.1 1273493 R 243243 CDS YP_880567.1 118465333 4526529 1273905..1274108 1 NC_008595.1 hypothetical protein 1274108 4526529 MAV_1323 Mycobacterium avium 104 hypothetical protein YP_880567.1 1273905 D 243243 CDS YP_880568.1 118463061 4528341 complement(1274105..1275196) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1275196 4528341 MAV_1322 Mycobacterium avium 104 PPE family protein YP_880568.1 1274105 R 243243 CDS YP_880569.1 118465040 4525819 complement(1275232..1276419) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1276419 4525819 MAV_1324 Mycobacterium avium 104 PPE family protein YP_880569.1 1275232 R 243243 CDS YP_880570.1 118465717 4527452 1277231..1277923 1 NC_008595.1 identified by match to protein family HMM PF01583; match to protein family HMM TIGR00455; adenylylsulfate kinase 1277923 cysC 4527452 cysC Mycobacterium avium 104 adenylylsulfate kinase YP_880570.1 1277231 D 243243 CDS YP_880571.1 118463830 4526048 1277920..1279179 1 NC_008595.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; sulfate adenylyltransferase 1279179 sat 4526048 sat Mycobacterium avium 104 sulfate adenylyltransferase YP_880571.1 1277920 D 243243 CDS YP_880572.1 118464621 4526778 1279176..1279508 1 NC_008595.1 hypothetical protein 1279508 4526778 MAV_1327 Mycobacterium avium 104 hypothetical protein YP_880572.1 1279176 D 243243 CDS YP_880573.1 118462725 4530099 complement(1279519..1281258) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1281258 4530099 MAV_1328 Mycobacterium avium 104 acyl-CoA synthetase YP_880573.1 1279519 R 243243 CDS YP_880574.1 118463459 4529701 complement(1281367..1283034) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1283034 4529701 MAV_1329 Mycobacterium avium 104 PPE family protein YP_880574.1 1281367 R 243243 CDS YP_880575.1 118466835 4526944 complement(1283388..1284980) 1 NC_008595.1 hypothetical protein 1284980 4526944 MAV_1330 Mycobacterium avium 104 hypothetical protein YP_880575.1 1283388 R 243243 CDS YP_880576.1 118462320 4529638 1285038..1286705 1 NC_008595.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236; 1-pyrroline-5-carboxylate dehydrogenase 1286705 pruA 4529638 pruA Mycobacterium avium 104 1-pyrroline-5-carboxylate dehydrogenase YP_880576.1 1285038 D 243243 CDS YP_880577.1 118464208 4526888 1286705..1287667 1 NC_008595.1 identified by match to protein family HMM PF01619; proline dehydrogenase 1287667 4526888 MAV_1332 Mycobacterium avium 104 proline dehydrogenase YP_880577.1 1286705 D 243243 CDS YP_880578.1 118464355 4529157 complement(1287760..1288362) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1288362 4529157 MAV_1333 Mycobacterium avium 104 TetR family transcriptional regulator YP_880578.1 1287760 R 243243 CDS YP_880579.1 118463796 4525878 complement(1288383..1289552) 1 NC_008595.1 lipid-transfer protein 1289552 4525878 MAV_1334 Mycobacterium avium 104 lipid-transfer protein YP_880579.1 1288383 R 243243 CDS YP_880580.1 118466086 4527354 complement(1289549..1290010) 1 NC_008595.1 hypothetical protein 1290010 4527354 MAV_1335 Mycobacterium avium 104 hypothetical protein YP_880580.1 1289549 R 243243 CDS YP_880581.1 118463127 4529652 complement(1290007..1291128) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 1291128 4529652 MAV_1336 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880581.1 1290007 R 243243 CDS YP_880582.1 118462902 4528165 complement(1292105..1293289) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 1293289 4528165 MAV_1338 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880582.1 1292105 R 243243 CDS YP_880583.1 118462351 4527978 complement(1293294..1294490) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1294490 4527978 MAV_1339 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880583.1 1293294 R 243243 CDS YP_880584.1 118466594 4529360 1294685..1296145 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1296145 4529360 MAV_1340 Mycobacterium avium 104 aldehyde dehydrogenase YP_880584.1 1294685 D 243243 CDS YP_880585.1 118463199 4527526 1296142..1298433 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 1298433 4527526 MAV_1341 Mycobacterium avium 104 caib/baif family protein YP_880585.1 1296142 D 243243 CDS YP_880586.1 118467128 4526155 1298494..1299402 1 NC_008595.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta hydrolase family protein 1299402 4526155 MAV_1342 Mycobacterium avium 104 hydrolase, alpha/beta hydrolase family protein YP_880586.1 1298494 D 243243 CDS YP_880587.1 118465336 4526532 1299432..1300853 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1300853 4526532 MAV_1343 Mycobacterium avium 104 acyl-CoA synthetase YP_880587.1 1299432 D 243243 CDS YP_880588.1 118465725 4527460 1300972..1302306 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family protein transporter 1302306 4527460 MAV_1344 Mycobacterium avium 104 major facilitator family protein transporter YP_880588.1 1300972 D 243243 CDS YP_880589.1 118463951 4526603 complement(1302308..1303261) 1 NC_008595.1 tetrahydropicolinate succinylase 1303261 4526603 MAV_1345 Mycobacterium avium 104 tetrahydropicolinate succinylase YP_880589.1 1302308 R 243243 CDS YP_880590.1 118463687 4528534 1303581..1304417 1 NC_008595.1 identified by match to protein family HMM PF00934; PE family protein 1304417 4528534 MAV_1346 Mycobacterium avium 104 PE family protein YP_880590.1 1303581 D 243243 CDS YP_880591.1 118464457 4527050 1304443..1305594 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1305594 4527050 MAV_1347 Mycobacterium avium 104 PPE family protein YP_880591.1 1304443 D 243243 CDS YP_880592.1 118462942 4530227 1305644..1306708 1 NC_008595.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 1306708 dapE 4530227 dapE Mycobacterium avium 104 succinyl-diaminopimelate desuccinylase YP_880592.1 1305644 D 243243 CDS YP_880593.1 118462245 4526931 complement(1306693..1308831) 1 NC_008595.1 identified by match to protein family HMM PF07721; TPR repeat-containing protein 1308831 4526931 MAV_1348 Mycobacterium avium 104 TPR repeat-containing protein YP_880593.1 1306693 R 243243 CDS YP_880594.1 118463799 4525881 1308920..1309483 1 NC_008595.1 identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein 1309483 4525881 MAV_1350 Mycobacterium avium 104 hypothetical protein YP_880594.1 1308920 D 243243 CDS YP_880595.1 118464586 4530291 1309626..1311404 1 NC_008595.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase 1311404 4530291 MAV_1351 Mycobacterium avium 104 long-chain-acyl-CoA synthetase YP_880595.1 1309626 D 243243 CDS YP_880596.1 118463792 4525873 1311460..1312335 1 NC_008595.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 1312335 folP 4525873 folP Mycobacterium avium 104 dihydropteroate synthase YP_880596.1 1311460 D 243243 CDS YP_880597.1 118464429 4530250 1312332..1313321 1 NC_008595.1 identified by match to protein family HMM PF00535; glucosyl-3-phosphoglycerate synthase 1313321 4530250 MAV_1353 Mycobacterium avium 104 glucosyl-3-phosphoglycerate synthase YP_880597.1 1312332 D 243243 CDS YP_880598.1 118462280 4529285 1313373..1313723 1 NC_008595.1 hypothetical protein 1313723 4529285 MAV_1354 Mycobacterium avium 104 hypothetical protein YP_880598.1 1313373 D 243243 CDS YP_880599.1 118462934 4530218 1313726..1314307 1 NC_008595.1 identified by match to protein family HMM PF03352; match to protein family HMM TIGR00624; DNA-3-methyladenine glycosylase I 1314307 4530218 MAV_1355 Mycobacterium avium 104 DNA-3-methyladenine glycosylase I YP_880599.1 1313726 D 243243 CDS YP_880600.1 118467246 4526081 1314474..1314647 1 NC_008595.1 hypothetical protein 1314647 4526081 MAV_1356 Mycobacterium avium 104 hypothetical protein YP_880600.1 1314474 D 243243 CDS YP_880601.1 118466596 4529362 complement(1314677..1315957) 1 NC_008595.1 identified by match to protein family HMM PF00534; match to protein family HMM TIGR02149; glycogen synthase 1315957 4529362 MAV_1357 Mycobacterium avium 104 glycogen synthase YP_880601.1 1314677 R 243243 CDS YP_880602.1 118467276 4527078 1316039..1317235 1 NC_008595.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1317235 glgC 4527078 glgC Mycobacterium avium 104 glucose-1-phosphate adenylyltransferase YP_880602.1 1316039 D 243243 CDS YP_880603.1 118463414 4530051 complement(1317315..1319009) 1 NC_008595.1 identified by match to protein family HMM PF02129; match to protein family HMM TIGR00976; hydrolase CocE/NonD family protein 1319009 4530051 MAV_1359 Mycobacterium avium 104 hydrolase CocE/NonD family protein YP_880603.1 1317315 R 243243 CDS YP_880604.1 118462820 4529040 complement(1319039..1319713) 1 NC_008595.1 identified by match to protein family HMM PF04140; isoprenylcysteine carboxyl methyltransferase (icmt) family protein 1319713 4529040 MAV_1360 Mycobacterium avium 104 isoprenylcysteine carboxyl methyltransferase (icmt) family protein YP_880604.1 1319039 R 243243 CDS YP_880605.1 118466940 4527775 complement(1319723..1321366) 1 NC_008595.1 ABC transporter transmembrane protein 1321366 4527775 MAV_1361 Mycobacterium avium 104 ABC transporter transmembrane protein YP_880605.1 1319723 R 243243 CDS YP_880606.1 118466582 4527372 complement(1321363..1322307) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1322307 4527372 MAV_1362 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880606.1 1321363 R 243243 CDS YP_880607.1 118465256 4528474 complement(1322297..1322944) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1322944 4528474 MAV_1363 Mycobacterium avium 104 TetR family transcriptional regulator YP_880607.1 1322297 R 243243 CDS YP_880608.1 118462864 4527091 complement(1323101..1323769) 1 NC_008595.1 identified by match to protein family HMM PF01596; match to protein family HMM PF05175; O-methyltransferase, family protein 3 1323769 4527091 MAV_1364 Mycobacterium avium 104 O-methyltransferase, family protein 3 YP_880608.1 1323101 R 243243 CDS YP_880609.1 118463820 4526076 1323971..1325245 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase sigma-70 factor 1325245 4526076 MAV_1365 Mycobacterium avium 104 RNA polymerase sigma-70 factor YP_880609.1 1323971 D 243243 CDS YP_880610.1 118467265 4527067 1325386..1326900 1 NC_008595.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; trypsin 1326900 4527067 MAV_1366 Mycobacterium avium 104 trypsin YP_880610.1 1325386 D 243243 CDS YP_880611.1 118462872 4527100 1326900..1327295 1 NC_008595.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 1327295 4527100 MAV_1367 Mycobacterium avium 104 sec-independent translocase YP_880611.1 1326900 D 243243 CDS YP_880612.1 118465805 4526118 complement(1327300..1328457) 1 NC_008595.1 identified by match to protein family HMM PF01883; Mrp protein 1328457 4526118 MAV_1368 Mycobacterium avium 104 Mrp protein YP_880612.1 1327300 R 243243 CDS YP_880613.1 118466691 4530433 complement(1328515..1329756) 1 NC_008595.1 hypothetical protein 1329756 4530433 MAV_1369 Mycobacterium avium 104 hypothetical protein YP_880613.1 1328515 R 243243 CDS YP_880614.1 118466846 4526955 complement(1329959..1330501) 1 NC_008595.1 identified by match to protein family HMM PF06210; integral membrane protein 1330501 4526955 MAV_1370 Mycobacterium avium 104 integral membrane protein YP_880614.1 1329959 R 243243 CDS YP_880615.1 118463445 4529687 complement(1330498..1331787) 1 NC_008595.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03448; Mg/Co/Ni transporter MgtE 1331787 4529687 MAV_1371 Mycobacterium avium 104 Mg/Co/Ni transporter MgtE YP_880615.1 1330498 R 243243 CDS YP_880616.1 118463393 4528020 complement(1331850..1332443) 1 NC_008595.1 hypothetical protein 1332443 4528020 MAV_1372 Mycobacterium avium 104 hypothetical protein YP_880616.1 1331850 R 243243 CDS YP_880617.1 118465736 4525699 1332669..1333124 1 NC_008595.1 hypothetical protein 1333124 4525699 MAV_1373 Mycobacterium avium 104 hypothetical protein YP_880617.1 1332669 D 243243 CDS YP_880618.1 118464983 4527475 1333149..1334561 1 NC_008595.1 identified by match to protein family HMM PF01547; extracellular solute-binding protein 1334561 4527475 MAV_1374 Mycobacterium avium 104 extracellular solute-binding protein YP_880618.1 1333149 D 243243 CDS YP_880619.1 118462792 4525760 1334615..1335493 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 1335493 sugA 4525760 sugA Mycobacterium avium 104 ABC transporter permease YP_880619.1 1334615 D 243243 CDS YP_880620.1 118463177 4529880 1335528..1336322 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 1336322 sugB 4529880 sugB Mycobacterium avium 104 ABC transporter permease YP_880620.1 1335528 D 243243 CDS YP_880621.1 118466110 4527739 1336327..1337505 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1337505 sugC 4527739 sugC Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880621.1 1336327 D 243243 CDS YP_880622.1 118467248 4526083 1337502..1338095 1 NC_008595.1 hypothetical protein 1338095 4526083 MAV_1378 Mycobacterium avium 104 hypothetical protein YP_880622.1 1337502 D 243243 CDS YP_880623.1 118465003 4526269 complement(1338199..1339299) 1 NC_008595.1 identified by match to protein family HMM PF01544; match to protein family HMM TIGR00383; magnesium and cobalt transport protein CorA 1339299 corA 4526269 corA Mycobacterium avium 104 magnesium and cobalt transport protein CorA YP_880623.1 1338199 R 243243 CDS YP_880624.1 118465490 4526786 1339489..1340478 1 NC_008595.1 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 1340478 4526786 MAV_1380 Mycobacterium avium 104 malate dehydrogenase YP_880624.1 1339489 D 243243 CDS YP_880625.1 118466126 4529759 1340531..1341733 1 NC_008595.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949; NAD-dependent malic enzyme 1341733 4529759 MAV_1381 Mycobacterium avium 104 NAD-dependent malic enzyme YP_880625.1 1340531 D 243243 CDS YP_880626.1 118467000 4529528 1341730..1342599 1 NC_008595.1 identified by match to protein family HMM PF04069; LpqZ protein 1342599 4529528 MAV_1383 Mycobacterium avium 104 LpqZ protein YP_880626.1 1341730 D 243243 CDS YP_880627.1 118465033 4525812 complement(1342596..1343447) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain alcohol dehydrogenase 1343447 4525812 MAV_1382 Mycobacterium avium 104 short chain alcohol dehydrogenase YP_880627.1 1342596 R 243243 CDS YP_880628.1 118463296 4525991 complement(1343523..1344347) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain alcohol dehydrogenase 1344347 4525991 MAV_1384 Mycobacterium avium 104 short chain alcohol dehydrogenase YP_880628.1 1343523 R 243243 CDS YP_880629.1 118466948 4530260 complement(1348429..1349202) 1 NC_008595.1 hypothetical protein 1349202 4530260 MAV_1386 Mycobacterium avium 104 hypothetical protein YP_880629.1 1348429 R 243243 CDS YP_880630.1 118464957 4528697 1349579..1351459 1 NC_008595.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; drug transporter 1351459 4528697 MAV_1387 Mycobacterium avium 104 drug transporter YP_880630.1 1349579 D 243243 CDS YP_880631.1 118465360 4529220 complement(1351464..1354877) 1 NC_008595.1 ATPase 1354877 4529220 MAV_1388 Mycobacterium avium 104 ATPase YP_880631.1 1351464 R 243243 CDS YP_880632.1 118465592 4527140 complement(1354929..1356113) 1 NC_008595.1 identified by match to protein family HMM PF00067; NikQ protein 1356113 4527140 MAV_1389 Mycobacterium avium 104 NikQ protein YP_880632.1 1354929 R 243243 CDS YP_880633.1 118463952 4526604 complement(1356146..1356700) 1 NC_008595.1 hypothetical protein 1356700 4526604 MAV_1390 Mycobacterium avium 104 hypothetical protein YP_880633.1 1356146 R 243243 CDS YP_880634.1 118463347 4529881 complement(1356734..1357504) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 1357504 4529881 MAV_1391 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_880634.1 1356734 R 243243 CDS YP_880635.1 118466165 4528788 complement(1357553..1358164) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 1358164 pcaC 4528788 pcaC Mycobacterium avium 104 hypothetical protein YP_880635.1 1357553 R 243243 CDS YP_880636.1 118464239 4528612 complement(1358202..1359038) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1359038 4528612 MAV_1393 Mycobacterium avium 104 carveol dehydrogenase YP_880636.1 1358202 R 243243 CDS YP_880637.1 118464345 4529147 1359313..1359798 1 NC_008595.1 hypothetical protein 1359798 4529147 MAV_1394 Mycobacterium avium 104 hypothetical protein YP_880637.1 1359313 D 243243 CDS YP_880638.1 118465202 4530399 1359912..1360646 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase 1360646 4530399 MAV_1395 Mycobacterium avium 104 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase YP_880638.1 1359912 D 243243 CDS YP_880639.1 118464501 4525544 1360697..1360918 1 NC_008595.1 hypothetical protein 1360918 4525544 MAV_1396 Mycobacterium avium 104 hypothetical protein YP_880639.1 1360697 D 243243 CDS YP_880640.1 118466060 4530030 1360915..1362279 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1362279 4530030 MAV_1397 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880640.1 1360915 D 243243 CDS YP_880641.1 118466211 4528890 1363433..1364476 1 NC_008595.1 identified by match to protein family HMM PF03447; homoserine dehydrogenase 1364476 4528890 MAV_1399 Mycobacterium avium 104 homoserine dehydrogenase YP_880641.1 1363433 D 243243 CDS YP_880642.1 118464232 4528605 complement(1364550..1365137) 1 NC_008595.1 LprE protein 1365137 4528605 MAV_1400 Mycobacterium avium 104 LprE protein YP_880642.1 1364550 R 243243 CDS YP_880643.1 118462257 4526400 1365258..1366958 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; ATP-dependent rna helicase, dead/deah box family protein 1366958 4526400 MAV_1401 Mycobacterium avium 104 ATP-dependent rna helicase, dead/deah box family protein YP_880643.1 1365258 D 243243 CDS YP_880644.1 118464481 4528855 1366955..1368094 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase, putative 1368094 4528855 MAV_1402 Mycobacterium avium 104 acyltransferase, putative YP_880644.1 1366955 D 243243 CDS YP_880645.1 118462230 4525567 complement(1368283..1368876) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1368876 4525567 MAV_1403 Mycobacterium avium 104 TetR family transcriptional regulator YP_880645.1 1368283 R 243243 CDS YP_880646.1 118465845 4530638 complement(1368876..1370105) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 130 1370105 4530638 MAV_1404 Mycobacterium avium 104 cytochrome P450 130 YP_880646.1 1368876 R 243243 CDS YP_880647.1 118462999 4530629 complement(1370245..1371612) 1 NC_008595.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding 1371612 4530629 MAV_1405 Mycobacterium avium 104 oxidoreductase, FAD-binding YP_880647.1 1370245 R 243243 CDS YP_880648.1 118463726 4528076 complement(1371633..1372850) 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 1372850 4528076 MAV_1406 Mycobacterium avium 104 transporter, major facilitator family protein YP_880648.1 1371633 R 243243 CDS YP_880649.1 118464467 4527060 1372952..1373779 1 NC_008595.1 identified by match to protein family HMM PF03167; uracil-DNA glycosylase 1373779 4527060 MAV_1407 Mycobacterium avium 104 uracil-DNA glycosylase YP_880649.1 1372952 D 243243 CDS YP_880650.1 118465430 4529979 1373786..1374913 1 NC_008595.1 identified by match to protein family HMM PF01494; hypothetical protein 1374913 4529979 MAV_1408 Mycobacterium avium 104 hypothetical protein YP_880650.1 1373786 D 243243 CDS YP_880651.1 118464858 4527974 1374970..1376001 1 NC_008595.1 identified by match to protein family HMM PF00296; alkanal monooxygenase alpha chain 1376001 4527974 MAV_1409 Mycobacterium avium 104 alkanal monooxygenase alpha chain YP_880651.1 1374970 D 243243 CDS YP_880652.1 118466529 4527202 complement(1376015..1379929) 1 NC_008595.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254; cyclic diguanylate phosphodiesterase domain-containing protein 1379929 4527202 MAV_1410 Mycobacterium avium 104 cyclic diguanylate phosphodiesterase domain-containing protein YP_880652.1 1376015 R 243243 CDS YP_880653.1 118463950 4526602 1379954..1380073 1 NC_008595.1 hypothetical protein 1380073 4526602 MAV_1412 Mycobacterium avium 104 hypothetical protein YP_880653.1 1379954 D 243243 CDS YP_880654.1 118467108 4526370 complement(1380061..1380504) 1 NC_008595.1 identified by match to protein family HMM PF01230; HIT family protein 1380504 4526370 MAV_1411 Mycobacterium avium 104 HIT family protein YP_880654.1 1380061 R 243243 CDS YP_880655.1 118463408 4530045 1380578..1381963 1 NC_008595.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1381963 4530045 MAV_1414 Mycobacterium avium 104 amidase YP_880655.1 1380578 D 243243 CDS YP_880656.1 118462625 4526427 complement(1381960..1382457) 1 NC_008595.1 T/U mismatch-specific DNA glycosylase 1382457 4526427 MAV_1413 Mycobacterium avium 104 T/U mismatch-specific DNA glycosylase YP_880656.1 1381960 R 243243 CDS YP_880657.1 118463572 4530727 1382456..1383613 1 NC_008595.1 identified by match to protein family HMM PF00211; chain A, Myco adenylyl cyclase, holoenzyme, inhibited state 1383613 4530727 MAV_1415 Mycobacterium avium 104 chain A, Myco adenylyl cyclase, holoenzyme, inhibited state YP_880657.1 1382456 D 243243 CDS YP_880658.1 118464316 4526647 1383903..1384478 1 NC_008595.1 hypothetical protein 1384478 4526647 MAV_1416 Mycobacterium avium 104 hypothetical protein YP_880658.1 1383903 D 243243 CDS YP_880659.1 118465657 4526729 complement(1384525..1386339) 1 NC_008595.1 identified by match to protein family HMM PF00069; serine/threonine protein kinase 1386339 4526729 MAV_1417 Mycobacterium avium 104 serine/threonine protein kinase YP_880659.1 1384525 R 243243 CDS YP_880660.1 118465098 4529989 complement(1386437..1387582) 1 NC_008595.1 identified by match to protein family HMM PF00486; match to protein family HMM PF00498; match to protein family HMM PF03704; transcriptional regulator 1387582 4529989 MAV_1418 Mycobacterium avium 104 transcriptional regulator YP_880660.1 1386437 R 243243 CDS YP_880661.1 118462738 4527809 complement(1387692..1388024) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 1388024 4527809 MAV_1419 Mycobacterium avium 104 hypothetical protein YP_880661.1 1387692 R 243243 CDS YP_880662.1 118467271 4527073 complement(1388171..1390087) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter 1390087 4527073 MAV_1420 Mycobacterium avium 104 ABC transporter YP_880662.1 1388171 R 243243 CDS YP_880663.1 118464147 4526456 complement(1390084..1391841) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1391841 4526456 MAV_1421 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880663.1 1390084 R 243243 CDS YP_880664.1 118462937 4530222 complement(1391902..1392036) 1 NC_008595.1 hypothetical protein 1392036 4530222 MAV_1422 Mycobacterium avium 104 hypothetical protein YP_880664.1 1391902 R 243243 CDS YP_880665.1 118464412 4530806 1392065..1392580 1 NC_008595.1 LprB protein 1392580 4530806 MAV_1423 Mycobacterium avium 104 LprB protein YP_880665.1 1392065 D 243243 CDS YP_880666.1 118463235 4528809 1392577..1393146 1 NC_008595.1 LprC protein 1393146 4528809 MAV_1424 Mycobacterium avium 104 LprC protein YP_880666.1 1392577 D 243243 CDS YP_880667.1 118465254 4528472 complement(1393173..1393676) 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 1393676 4528472 MAV_1425 Mycobacterium avium 104 phosphoglycerate mutase YP_880667.1 1393173 R 243243 CDS YP_880668.1 118464547 4530417 complement(1393708..1395126) 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 1395126 4530417 MAV_1426 Mycobacterium avium 104 hypothetical protein YP_880668.1 1393708 R 243243 CDS YP_880669.1 118464837 4529742 1395385..1396536 1 NC_008595.1 identified by match to protein family HMM PF00149; DNA repair exonuclease 1396536 4529742 MAV_1427 Mycobacterium avium 104 DNA repair exonuclease YP_880669.1 1395385 D 243243 CDS YP_880670.1 118465536 4530012 1396533..1399163 1 NC_008595.1 hypothetical protein 1399163 4530012 MAV_1428 Mycobacterium avium 104 hypothetical protein YP_880670.1 1396533 D 243243 CDS YP_880671.1 118462396 4525940 1399227..1400471 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1400471 4525940 MAV_1430 Mycobacterium avium 104 alpha/beta hydrolase YP_880671.1 1399227 D 243243 CDS YP_880672.1 118466845 4526954 complement(1400458..1402134) 1 NC_008595.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein, family protein 5 1402134 4526954 MAV_1429 Mycobacterium avium 104 extracellular solute-binding protein, family protein 5 YP_880672.1 1400458 R 243243 CDS YP_880673.1 118463160 4529861 complement(1402145..1403980) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1403980 oppD 4529861 oppD Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880673.1 1402145 R 243243 CDS YP_880674.1 118463250 4525786 complement(1403977..1404903) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 1404903 oppC 4525786 oppC Mycobacterium avium 104 ABC transporter permease YP_880674.1 1403977 R 243243 CDS YP_880675.1 118465746 4525709 complement(1404900..1405874) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 1405874 oppB 4525709 oppB Mycobacterium avium 104 ABC transporter permease YP_880675.1 1404900 R 243243 CDS YP_880676.1 118465022 4530071 1406023..1406514 1 NC_008595.1 identified by match to protein family HMM PF00484; carbonic anhydrase 1406514 4530071 MAV_1434 Mycobacterium avium 104 carbonic anhydrase YP_880676.1 1406023 D 243243 CDS YP_880677.1 118463843 4529942 complement(1406646..1407035) 1 NC_008595.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1407035 4529942 MAV_1435 Mycobacterium avium 104 hypothetical protein YP_880677.1 1406646 R 243243 CDS YP_880678.1 118465471 4527224 1407255..1408199 1 NC_008595.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1408199 cysD 4527224 cysD Mycobacterium avium 104 sulfate adenylyltransferase subunit 2 YP_880678.1 1407255 D 243243 CDS YP_880679.1 118464038 4529010 1408199..1410049 1 NC_008595.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein 1410049 cysNC 4529010 cysNC Mycobacterium avium 104 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein YP_880679.1 1408199 D 243243 CDS YP_880680.1 118464782 4529137 1410114..1410593 1 NC_008595.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; StaS protein 1410593 4529137 MAV_1439 Mycobacterium avium 104 StaS protein YP_880680.1 1410114 D 243243 CDS YP_880681.1 118462613 4528517 complement(1410590..1410985) 1 NC_008595.1 glyoxalase/bleomycin resistance protein/dioxygenase 1410985 4528517 MAV_1438 Mycobacterium avium 104 glyoxalase/bleomycin resistance protein/dioxygenase YP_880681.1 1410590 R 243243 CDS YP_880682.1 118466897 4528411 complement(1411037..1411450) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase/bleomycin resistance protein/dioxygenase 1411450 4528411 MAV_1440 Mycobacterium avium 104 glyoxalase/bleomycin resistance protein/dioxygenase YP_880682.1 1411037 R 243243 CDS YP_880683.1 118467121 4526148 1411517..1412395 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 1412395 4526148 MAV_1441 Mycobacterium avium 104 hypothetical protein YP_880683.1 1411517 D 243243 CDS YP_880684.1 118465143 4529175 1412457..1413329 1 NC_008595.1 hypothetical protein 1413329 4529175 MAV_1442 Mycobacterium avium 104 hypothetical protein YP_880684.1 1412457 D 243243 CDS YP_880685.1 118466002 4528446 complement(1413354..1415099) 1 NC_008595.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885; TrkA domain-containing protein 1415099 4528446 MAV_1443 Mycobacterium avium 104 TrkA domain-containing protein YP_880685.1 1413354 R 243243 CDS YP_880686.1 118463632 4527336 complement(1415193..1415564) 1 NC_008595.1 identified by match to protein family HMM PF02136; steroid delta-isomerase 1415564 4527336 MAV_1444 Mycobacterium avium 104 steroid delta-isomerase YP_880686.1 1415193 R 243243 CDS YP_880687.1 118464183 4526493 1415588..1416193 1 NC_008595.1 identified by match to protein family HMM PF00293; nudix hydrolase 1416193 4526493 MAV_1446 Mycobacterium avium 104 nudix hydrolase YP_880687.1 1415588 D 243243 CDS YP_880688.1 118466754 4526355 complement(1416181..1416468) 1 NC_008595.1 hypothetical protein 1416468 4526355 MAV_1445 Mycobacterium avium 104 hypothetical protein YP_880688.1 1416181 R 243243 CDS YP_880689.1 118464173 4526483 complement(1416666..1417367) 1 NC_008595.1 hypothetical protein 1417367 4526483 MAV_1447 Mycobacterium avium 104 hypothetical protein YP_880689.1 1416666 R 243243 CDS YP_880690.1 118464766 4529120 1417477..1417983 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 1417983 4529120 MAV_1448 Mycobacterium avium 104 hypothetical protein YP_880690.1 1417477 D 243243 CDS YP_880691.1 118466757 4530752 complement(1418104..1418547) 1 NC_008595.1 hypothetical protein 1418547 4530752 MAV_1449 Mycobacterium avium 104 hypothetical protein YP_880691.1 1418104 R 243243 CDS YP_880692.1 118464060 4529500 complement(1418532..1419593) 1 NC_008595.1 hypothetical protein 1419593 4529500 MAV_1450 Mycobacterium avium 104 hypothetical protein YP_880692.1 1418532 R 243243 CDS YP_880693.1 118465919 4529001 complement(1419593..1419886) 1 NC_008595.1 identified by similarity to RF:NP_855753.1; hypothetical protein 1419886 4529001 MAV_1451 Mycobacterium avium 104 hypothetical protein YP_880693.1 1419593 R 243243 CDS YP_880694.1 118465914 4528996 complement(1420070..1421179) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1421179 4528996 MAV_1452 Mycobacterium avium 104 transposase, Mutator family protein YP_880694.1 1420070 R 243243 CDS YP_880695.1 118465014 4530063 complement(1421254..1421676) 1 NC_008595.1 transposase 1421676 4530063 MAV_1453 Mycobacterium avium 104 transposase YP_880695.1 1421254 R 243243 CDS YP_880696.1 118467059 4526437 complement(1421722..1422561) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1422561 4526437 MAV_1454 Mycobacterium avium 104 transposase YP_880696.1 1421722 R 243243 CDS YP_880697.1 118466149 4527915 complement(1422639..1422983) 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 1422983 4527915 MAV_1455 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_880697.1 1422639 R 243243 CDS YP_880698.1 118462939 4530224 complement(1423006..1423197) 1 NC_008595.1 hypothetical protein 1423197 4530224 MAV_1456 Mycobacterium avium 104 hypothetical protein YP_880698.1 1423006 R 243243 CDS YP_880699.1 118463391 4528018 complement(1423250..1424491) 1 NC_008595.1 hypothetical protein 1424491 4528018 MAV_1457 Mycobacterium avium 104 hypothetical protein YP_880699.1 1423250 R 243243 CDS YP_880700.1 118462842 4526024 1424505..1425779 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1425779 4526024 MAV_1458 Mycobacterium avium 104 transposase, Mutator family protein YP_880700.1 1424505 D 243243 CDS YP_880701.1 118466734 4530672 1426421..1426618 1 NC_008595.1 XRE family transcriptional regulator 1426618 4530672 MAV_1459 Mycobacterium avium 104 XRE family transcriptional regulator YP_880701.1 1426421 D 243243 CDS YP_880702.1 118466217 4528896 complement(1427273..1428580) 1 NC_008595.1 identified by match to protein family HMM PF00004; cell division cycle protein 48 1428580 4528896 MAV_1460 Mycobacterium avium 104 cell division cycle protein 48 YP_880702.1 1427273 R 243243 CDS YP_880703.1 118465547 4525795 complement(1428718..1428936) 1 NC_008595.1 hypothetical protein 1428936 4525795 MAV_1461 Mycobacterium avium 104 hypothetical protein YP_880703.1 1428718 R 243243 CDS YP_880704.1 118466164 4528787 complement(1429129..1429311) 1 NC_008595.1 hypothetical protein 1429311 4528787 MAV_1462 Mycobacterium avium 104 hypothetical protein YP_880704.1 1429129 R 243243 CDS YP_880705.1 118463003 4530633 1429553..1430440 1 NC_008595.1 identified by match to protein family HMM PF00155; aminotransferase, classes I and II family protein 1430440 4530633 MAV_1464 Mycobacterium avium 104 aminotransferase, classes I and II family protein YP_880705.1 1429553 D 243243 CDS YP_880706.1 118464836 4529741 complement(1430394..1431698) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1431698 4529741 MAV_1463 Mycobacterium avium 104 transposase, Mutator family protein YP_880706.1 1430394 R 243243 CDS YP_880707.1 118462276 4529281 1431775..1432194 1 NC_008595.1 aminotransferase, classes I and II family protein 1432194 4529281 MAV_1465 Mycobacterium avium 104 aminotransferase, classes I and II family protein YP_880707.1 1431775 D 243243 CDS YP_880708.1 118467283 4527085 complement(1432291..1432917) 1 NC_008595.1 hypothetical protein 1432917 4527085 MAV_1466 Mycobacterium avium 104 hypothetical protein YP_880708.1 1432291 R 243243 CDS YP_880709.1 118466551 4529100 complement(1432924..1434597) 1 NC_008595.1 identified by match to protein family HMM PF06259; hypothetical protein 1434597 4529100 MAV_1467 Mycobacterium avium 104 hypothetical protein YP_880709.1 1432924 R 243243 CDS YP_880710.1 118465883 4527917 complement(1434891..1436165) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1436165 4527917 MAV_1468 Mycobacterium avium 104 transposase, Mutator family protein YP_880710.1 1434891 R 243243 CDS YP_880711.1 118467071 4526449 complement(1436159..1436440) 1 NC_008595.1 hypothetical protein 1436440 4526449 MAV_1469 Mycobacterium avium 104 hypothetical protein YP_880711.1 1436159 R 243243 CDS YP_880712.1 118465170 4528660 1436539..1436796 1 NC_008595.1 transposase 1436796 4528660 MAV_1471 Mycobacterium avium 104 transposase YP_880712.1 1436539 D 243243 CDS YP_880713.1 118465141 4529173 complement(1436786..1438138) 1 NC_008595.1 ISChy9, transposase OrfB 1438138 4529173 MAV_1470 Mycobacterium avium 104 ISChy9, transposase OrfB YP_880713.1 1436786 R 243243 CDS YP_880714.1 118465778 4526913 1438215..1438565 1 NC_008595.1 identified by match to protein family HMM PF01797; ISSoc3, OrfA transposase 1438565 4526913 MAV_1472 Mycobacterium avium 104 ISSoc3, OrfA transposase YP_880714.1 1438215 D 243243 CDS YP_880715.1 118462685 4530613 complement(1438578..1439495) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1439495 4530613 MAV_1473 Mycobacterium avium 104 transposase YP_880715.1 1438578 R 243243 CDS YP_880716.1 118463252 4525788 complement(1439495..1439770) 1 NC_008595.1 transposase 1439770 4525788 MAV_1474 Mycobacterium avium 104 transposase YP_880716.1 1439495 R 243243 CDS YP_880717.1 118464722 4529409 complement(1440784..1440978) 1 NC_008595.1 transposase 1440978 4529409 MAV_1476 Mycobacterium avium 104 transposase YP_880717.1 1440784 R 243243 CDS YP_880718.1 118462603 4528507 1440992..1441171 1 NC_008595.1 hypothetical protein 1441171 4528507 MAV_1477 Mycobacterium avium 104 hypothetical protein YP_880718.1 1440992 D 243243 CDS YP_880719.1 118463159 4527797 complement(1441979..1442449) 1 NC_008595.1 hypothetical protein 1442449 4527797 MAV_1478 Mycobacterium avium 104 hypothetical protein YP_880719.1 1441979 R 243243 CDS YP_880720.1 118464941 4528202 complement(1442413..1443501) 1 NC_008595.1 hypothetical protein 1443501 4528202 MAV_1479 Mycobacterium avium 104 hypothetical protein YP_880720.1 1442413 R 243243 CDS YP_880721.1 118465025 4530074 complement(1443501..1443794) 1 NC_008595.1 identified by similarity to RF:NP_855753.1; hypothetical protein 1443794 4530074 MAV_1480 Mycobacterium avium 104 hypothetical protein YP_880721.1 1443501 R 243243 CDS YP_880722.1 118465504 4526801 complement(1444205..1445401) 1 NC_008595.1 identified by match to protein family HMM PF01609; TnpC protein 1445401 4526801 MAV_1481 Mycobacterium avium 104 TnpC protein YP_880722.1 1444205 R 243243 CDS YP_880723.1 118466368 4529930 1445452..1446777 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1446777 4529930 MAV_1482 Mycobacterium avium 104 transposase, Mutator family protein YP_880723.1 1445452 D 243243 CDS YP_880724.1 118465265 4527286 complement(1446797..1446976) 1 NC_008595.1 hypothetical protein 1446976 4527286 MAV_1483 Mycobacterium avium 104 hypothetical protein YP_880724.1 1446797 R 243243 CDS YP_880725.1 118464288 4529576 1447189..1448295 1 NC_008595.1 identified by match to protein family HMM PF00589; integrase 1448295 4529576 MAV_1484 Mycobacterium avium 104 integrase YP_880725.1 1447189 D 243243 CDS YP_880726.1 118463585 4529770 1448472..1448696 1 NC_008595.1 hypothetical protein 1448696 4529770 MAV_1485 Mycobacterium avium 104 hypothetical protein YP_880726.1 1448472 D 243243 CDS YP_880727.1 118463038 4528879 1448829..1450232 1 NC_008595.1 gp54 protein 1450232 4528879 MAV_1486 Mycobacterium avium 104 gp54 protein YP_880727.1 1448829 D 243243 CDS YP_880728.1 118462636 4529376 1450253..1451377 1 NC_008595.1 hypothetical protein 1451377 4529376 MAV_1487 Mycobacterium avium 104 hypothetical protein YP_880728.1 1450253 D 243243 CDS YP_880729.1 118465608 4527867 1451590..1451748 1 NC_008595.1 hypothetical protein 1451748 4527867 MAV_1488 Mycobacterium avium 104 hypothetical protein YP_880729.1 1451590 D 243243 CDS YP_880730.1 118466604 4529370 1451753..1452253 1 NC_008595.1 hypothetical protein 1452253 4529370 MAV_1489 Mycobacterium avium 104 hypothetical protein YP_880730.1 1451753 D 243243 CDS YP_880731.1 118466047 4528055 1452250..1452720 1 NC_008595.1 flagellar hook-length control protein 1452720 4528055 MAV_1490 Mycobacterium avium 104 flagellar hook-length control protein YP_880731.1 1452250 D 243243 CDS YP_880732.1 118464171 4526481 1452717..1452869 1 NC_008595.1 hypothetical protein 1452869 4526481 MAV_1491 Mycobacterium avium 104 hypothetical protein YP_880732.1 1452717 D 243243 CDS YP_880733.1 118463600 4527547 1452897..1453601 1 NC_008595.1 identified by match to protein family HMM PF00239; Y4cG protein 1453601 4527547 MAV_1493 Mycobacterium avium 104 Y4cG protein YP_880733.1 1452897 D 243243 CDS YP_880734.1 118463658 4525950 complement(1453598..1453954) 1 NC_008595.1 identified by match to protein family HMM PF01022; transcriptional regulator 1453954 4525950 MAV_1492 Mycobacterium avium 104 transcriptional regulator YP_880734.1 1453598 R 243243 CDS YP_880735.1 118463084 4528907 1454007..1454531 1 NC_008595.1 identified by match to protein family HMM PF00903; cadmium inducible protein cadi 1454531 4528907 MAV_1494 Mycobacterium avium 104 cadmium inducible protein cadi YP_880735.1 1454007 D 243243 CDS YP_880736.1 118465109 4530461 1454536..1455642 1 NC_008595.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832; arsenical-resistance protein 1455642 arsB 4530461 arsB Mycobacterium avium 104 arsenical-resistance protein YP_880736.1 1454536 D 243243 CDS YP_880737.1 118467082 4526382 1455639..1456313 1 NC_008595.1 identified by match to protein family HMM PF01451; low molecular weight phosphotyrosine protein phosphatase 1456313 4526382 MAV_1496 Mycobacterium avium 104 low molecular weight phosphotyrosine protein phosphatase YP_880737.1 1455639 D 243243 CDS YP_880738.1 118463179 4527702 1456328..1456723 1 NC_008595.1 identified by match to protein family HMM PF01451; low molecular weight phosphotyrosine protein phosphatase 1456723 4527702 MAV_1497 Mycobacterium avium 104 low molecular weight phosphotyrosine protein phosphatase YP_880738.1 1456328 D 243243 CDS YP_880739.1 118462631 4526433 complement(1456873..1458147) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1458147 4526433 MAV_1498 Mycobacterium avium 104 transposase, Mutator family protein YP_880739.1 1456873 R 243243 CDS YP_880740.1 118464673 4528368 1458359..1458619 1 NC_008595.1 hypothetical protein 1458619 4528368 MAV_1499 Mycobacterium avium 104 hypothetical protein YP_880740.1 1458359 D 243243 CDS YP_880741.1 118464233 4528606 1458616..1459335 1 NC_008595.1 hypothetical protein 1459335 4528606 MAV_1500 Mycobacterium avium 104 hypothetical protein YP_880741.1 1458616 D 243243 CDS YP_880742.1 118465505 4526802 1459345..1460160 1 NC_008595.1 gp13 protein 1460160 4526802 MAV_1501 Mycobacterium avium 104 gp13 protein YP_880742.1 1459345 D 243243 CDS YP_880743.1 118465116 4530468 1460157..1460462 1 NC_008595.1 hypothetical protein 1460462 4530468 MAV_1502 Mycobacterium avium 104 hypothetical protein YP_880743.1 1460157 D 243243 CDS YP_880744.1 118463255 4528120 1460500..1461189 1 NC_008595.1 hypothetical protein 1461189 4528120 MAV_1503 Mycobacterium avium 104 hypothetical protein YP_880744.1 1460500 D 243243 CDS YP_880745.1 118467025 4526537 1461522..1463054 1 NC_008595.1 gp2 protein 1463054 4526537 MAV_1504 Mycobacterium avium 104 gp2 protein YP_880745.1 1461522 D 243243 CDS YP_880746.1 118462848 4526030 1463243..1463365 1 NC_008595.1 hypothetical protein 1463365 4526030 MAV_1505 Mycobacterium avium 104 hypothetical protein YP_880746.1 1463243 D 243243 CDS YP_880747.1 118464128 4528829 1465260..1466678 1 NC_008595.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1466678 lysA 4528829 lysA Mycobacterium avium 104 diaminopimelate decarboxylase YP_880747.1 1465260 D 243243 CDS YP_880748.1 118464687 4527876 1466682..1468007 1 NC_008595.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1468007 4527876 MAV_1509 Mycobacterium avium 104 homoserine dehydrogenase YP_880748.1 1466682 D 243243 CDS YP_880749.1 118466285 4529531 1468004..1469086 1 NC_008595.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1469086 thrC 4529531 thrC Mycobacterium avium 104 threonine synthase YP_880749.1 1468004 D 243243 CDS YP_880750.1 118462633 4526435 1469128..1470063 1 NC_008595.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1470063 thrB 4526435 thrB Mycobacterium avium 104 homoserine kinase YP_880750.1 1469128 D 243243 CDS YP_880751.1 118464575 4530279 1470192..1470338 1 NC_008595.1 hypothetical protein 1470338 4530279 MAV_1512 Mycobacterium avium 104 hypothetical protein YP_880751.1 1470192 D 243243 CDS YP_880752.1 118464927 4528567 1470394..1472184 1 NC_008595.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1472184 rho 4528567 rho Mycobacterium avium 104 transcription termination factor Rho YP_880752.1 1470394 D 243243 CDS YP_880753.1 118463580 4529765 complement(1472181..1472303) 1 NC_008595.1 hypothetical protein 1472303 4529765 MAV_1513 Mycobacterium avium 104 hypothetical protein YP_880753.1 1472181 R 243243 CDS YP_880754.1 118465454 4526222 1472286..1472528 1 NC_008595.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1472528 rpmE 4526222 rpmE Mycobacterium avium 104 50S ribosomal protein L31 YP_880754.1 1472286 D 243243 CDS YP_880755.1 118464752 4527648 1472625..1473698 1 NC_008595.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1473698 prfA 4527648 prfA Mycobacterium avium 104 peptide chain release factor 1 YP_880755.1 1472625 D 243243 CDS YP_880756.1 118465310 4526564 1473721..1474659 1 NC_008595.1 identified by match to protein family HMM PF05175; match to protein family HMM TIGR00536; modification methylase, HemK family protein 1474659 4526564 MAV_1517 Mycobacterium avium 104 modification methylase, HemK family protein YP_880756.1 1473721 D 243243 CDS YP_880757.1 118462898 4528161 1474659..1475318 1 NC_008595.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 1475318 4528161 MAV_1518 Mycobacterium avium 104 Sua5/YciO/YrdC/YwlC family protein YP_880757.1 1474659 D 243243 CDS YP_880758.1 118462355 4527983 1475345..1476568 1 NC_008595.1 identified by match to protein family HMM PF00953; glycosyl transferase, group 4 family protein 1476568 4527983 MAV_1519 Mycobacterium avium 104 glycosyl transferase, group 4 family protein YP_880758.1 1475345 D 243243 CDS YP_880759.1 118463390 4528017 1476784..1477266 1 NC_008595.1 hypothetical protein 1477266 4528017 MAV_1520 Mycobacterium avium 104 hypothetical protein YP_880759.1 1476784 D 243243 CDS YP_880760.1 118462240 4526925 1477259..1478017 1 NC_008595.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1478017 atpB 4526925 atpB Mycobacterium avium 104 F0F1 ATP synthase subunit A YP_880760.1 1477259 D 243243 CDS YP_880761.1 118467104 4526366 1478096..1478350 1 NC_008595.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1478350 4526366 MAV_1522 Mycobacterium avium 104 F0F1 ATP synthase subunit C YP_880761.1 1478096 D 243243 CDS YP_880762.1 118466607 4529373 1478357..1478893 1 NC_008595.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1478893 4529373 MAV_1523 Mycobacterium avium 104 F0F1 ATP synthase subunit B YP_880762.1 1478357 D 243243 CDS YP_880763.1 118465856 4530650 1478901..1480241 1 NC_008595.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1480241 4530650 MAV_1524 Mycobacterium avium 104 F0F1 ATP synthase subunit delta YP_880763.1 1478901 D 243243 CDS YP_880764.1 118465149 4529239 1480309..1481973 1 NC_008595.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1481973 atpA 4529239 atpA Mycobacterium avium 104 F0F1 ATP synthase subunit alpha YP_880764.1 1480309 D 243243 CDS YP_880765.1 118462468 4528722 1481980..1482894 1 NC_008595.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1482894 atpG 4528722 atpG Mycobacterium avium 104 F0F1 ATP synthase subunit gamma YP_880765.1 1481980 D 243243 CDS YP_880766.1 118464478 4528852 1482923..1484380 1 NC_008595.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1484380 atpD 4528852 atpD Mycobacterium avium 104 F0F1 ATP synthase subunit beta YP_880766.1 1482923 D 243243 CDS YP_880767.1 118467291 4527249 1484420..1484785 1 NC_008595.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1484785 atpC 4527249 atpC Mycobacterium avium 104 F0F1 ATP synthase subunit epsilon YP_880767.1 1484420 D 243243 CDS YP_880768.1 118465322 4526518 1484815..1485246 1 NC_008595.1 hypothetical protein 1485246 4526518 MAV_1530 Mycobacterium avium 104 hypothetical protein YP_880768.1 1484815 D 243243 CDS YP_880769.1 118462362 4527990 complement(1485243..1485830) 1 NC_008595.1 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; ATP:cob(I)alamin adenosyltransferase 1485830 4527990 MAV_1529 Mycobacterium avium 104 ATP:cob(I)alamin adenosyltransferase YP_880769.1 1485243 R 243243 CDS YP_880770.1 118462900 4528163 1485921..1487174 1 NC_008595.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1487174 murA 4528163 murA Mycobacterium avium 104 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_880770.1 1485921 D 243243 CDS YP_880771.1 118462294 4525639 1492858..1493355 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 1493355 4525639 MAV_1535 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_880771.1 1492858 D 243243 CDS YP_880772.1 118462974 4527402 complement(1493402..1493899) 1 NC_008595.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase 1493899 4527402 MAV_1536 Mycobacterium avium 104 methylated-DNA--protein-cysteine methyltransferase YP_880772.1 1493402 R 243243 CDS YP_880773.1 118463714 4528064 complement(1493896..1495395) 1 NC_008595.1 identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029; AraC family transcriptional regulator 1495395 4528064 MAV_1537 Mycobacterium avium 104 AraC family transcriptional regulator YP_880773.1 1493896 R 243243 CDS YP_880774.1 118464456 4527049 complement(1495481..1496365) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1496365 4527049 MAV_1538 Mycobacterium avium 104 LysR family transcriptional regulator YP_880774.1 1495481 R 243243 CDS YP_880775.1 118465134 4529165 1496450..1497694 1 NC_008595.1 identified by match to protein family HMM PF07690; major facilitator family protein transporter 1497694 4529165 MAV_1539 Mycobacterium avium 104 major facilitator family protein transporter YP_880775.1 1496450 D 243243 CDS YP_880776.1 118465998 4528442 complement(1498157..1499791) 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF00672; HAMP domain-containing protein 1499791 4528442 MAV_1540 Mycobacterium avium 104 HAMP domain-containing protein YP_880776.1 1498157 R 243243 CDS YP_880777.1 118466453 4527126 1499846..1500508 1 NC_008595.1 identified by match to protein family HMM PF01939; hypothetical protein 1500508 4527126 MAV_1541 Mycobacterium avium 104 hypothetical protein YP_880777.1 1499846 D 243243 CDS YP_880778.1 118465724 4527459 1500598..1500828 1 NC_008595.1 hypothetical protein 1500828 4527459 MAV_1542 Mycobacterium avium 104 hypothetical protein YP_880778.1 1500598 D 243243 CDS YP_880779.1 118467035 4526549 complement(1500839..1501303) 1 NC_008595.1 identified by match to protein family HMM PF00903; match to protein family HMM TIGR03081; methylmalonyl-CoA epimerase 1501303 mce 4526549 mce Mycobacterium avium 104 methylmalonyl-CoA epimerase YP_880779.1 1500839 R 243243 CDS YP_880780.1 118463966 4527212 1501385..1502566 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 1502566 4527212 MAV_1544 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880780.1 1501385 D 243243 CDS YP_880781.1 118464751 4527647 1502757..1503668 1 NC_008595.1 identified by match to protein family HMM PF00085; thioredoxin 1503668 4527647 MAV_1545 Mycobacterium avium 104 thioredoxin YP_880781.1 1502757 D 243243 CDS YP_880782.1 118466093 4527722 complement(1505923..1508007) 1 NC_008595.1 identified by match to protein family HMM PF00128; alpha-amylase 1508007 4527722 MAV_1547 Mycobacterium avium 104 alpha-amylase YP_880782.1 1505923 R 243243 CDS YP_880783.1 118465028 4530077 1508313..1510928 1 NC_008595.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094; alpha-glucan phosphorylase 1510928 4530077 MAV_1549 Mycobacterium avium 104 alpha-glucan phosphorylase YP_880783.1 1508313 D 243243 CDS YP_880784.1 118466949 4530261 complement(1510912..1512903) 1 NC_008595.1 identified by match to protein family HMM PF00270; DeaD/DeaH family protein helicase 1512903 4530261 MAV_1548 Mycobacterium avium 104 DeaD/DeaH family protein helicase YP_880784.1 1510912 R 243243 CDS YP_880785.1 118466524 4527197 complement(1512958..1514292) 1 NC_008595.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1514292 pncB 4527197 pncB Mycobacterium avium 104 nicotinate phosphoribosyltransferase YP_880785.1 1512958 R 243243 CDS YP_880786.1 118463948 4526600 1514360..1514677 1 NC_008595.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1514677 clpS 4526600 clpS Mycobacterium avium 104 ATP-dependent Clp protease adaptor protein ClpS YP_880786.1 1514360 D 243243 CDS YP_880787.1 118464515 4529435 1514702..1515289 1 NC_008595.1 hypothetical protein 1515289 4529435 MAV_1552 Mycobacterium avium 104 hypothetical protein YP_880787.1 1514702 D 243243 CDS YP_880788.1 118463943 4526595 1515300..1516340 1 NC_008595.1 identified by match to protein family HMM PF03576; peptidase T4 1516340 4526595 MAV_1553 Mycobacterium avium 104 peptidase T4 YP_880788.1 1515300 D 243243 CDS YP_880789.1 118464581 4530285 1516391..1517062 1 NC_008595.1 identified by match to protein family HMM PF01694; rhomboid family protein 1517062 4530285 MAV_1554 Mycobacterium avium 104 rhomboid family protein YP_880789.1 1516391 D 243243 CDS YP_880790.1 118465713 4527447 1517059..1517886 1 NC_008595.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1517886 murI 4527447 murI Mycobacterium avium 104 glutamate racemase YP_880790.1 1517059 D 243243 CDS YP_880791.1 118466764 4530759 1517977..1518741 1 NC_008595.1 identified by match to protein family HMM PF00753; metal-dependent hydrolase of the beta-lactamase III 1518741 4530759 MAV_1556 Mycobacterium avium 104 metal-dependent hydrolase of the beta-lactamase III YP_880791.1 1517977 D 243243 CDS YP_880792.1 118462847 4526029 1518775..1519554 1 NC_008595.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1519554 rph 4526029 rph Mycobacterium avium 104 ribonuclease PH YP_880792.1 1518775 D 243243 CDS YP_880793.1 118463331 4529201 1520032..1520646 1 NC_008595.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 1520646 rdgB 4529201 rdgB Mycobacterium avium 104 deoxyribonucleotide triphosphate pyrophosphatase YP_880793.1 1520032 D 243243 CDS YP_880794.1 118465408 4525668 complement(1520661..1521011) 1 NC_008595.1 hypothetical protein 1521011 4525668 MAV_1559 Mycobacterium avium 104 hypothetical protein YP_880794.1 1520661 R 243243 CDS YP_880795.1 118465051 4525830 complement(1521008..1521346) 1 NC_008595.1 hypothetical protein 1521346 4525830 MAV_1560 Mycobacterium avium 104 hypothetical protein YP_880795.1 1521008 R 243243 CDS YP_880796.1 118466481 4527611 1521879..1522430 1 NC_008595.1 hypothetical protein 1522430 4527611 MAV_1562 Mycobacterium avium 104 hypothetical protein YP_880796.1 1521879 D 243243 CDS YP_880797.1 118463041 4528882 1522432..1522884 1 NC_008595.1 LppJ protein 1522884 4528882 MAV_1563 Mycobacterium avium 104 LppJ protein YP_880797.1 1522432 D 243243 CDS YP_880798.1 118463183 4527706 complement(1522925..1523047) 1 NC_008595.1 hypothetical protein 1523047 4527706 MAV_1564 Mycobacterium avium 104 hypothetical protein YP_880798.1 1522925 R 243243 CDS YP_880799.1 118464139 4528841 1523092..1523424 1 NC_008595.1 hypothetical protein 1523424 4528841 MAV_1565 Mycobacterium avium 104 hypothetical protein YP_880799.1 1523092 D 243243 CDS YP_880800.1 118462514 4528592 1523800..1526388 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF04954; match to protein family HMM PF08021; ABC transporter ATP-binding protein 1526388 4528592 MAV_1566 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880800.1 1523800 D 243243 CDS YP_880801.1 118467076 4526454 1526385..1528121 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1528121 4526454 MAV_1567 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880801.1 1526385 D 243243 CDS YP_880802.1 118466527 4527200 1528209..1529276 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein, putative 1529276 4527200 MAV_1568 Mycobacterium avium 104 phosphotransferase enzyme family protein, putative YP_880802.1 1528209 D 243243 CDS YP_880803.1 118466023 4529909 complement(1529281..1529709) 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 1529709 4529909 MAV_1569 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_880803.1 1529281 R 243243 CDS YP_880804.1 118465413 4529962 complement(1529758..1530579) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1530579 4529962 MAV_1570 Mycobacterium avium 104 carveol dehydrogenase YP_880804.1 1529758 R 243243 CDS YP_880805.1 118464925 4528565 complement(1530579..1531772) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1531772 4528565 MAV_1571 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880805.1 1530579 R 243243 CDS YP_880806.1 118464350 4529152 1531949..1532689 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 1532689 4529152 MAV_1572 Mycobacterium avium 104 short chain dehydrogenase YP_880806.1 1531949 D 243243 CDS YP_880807.1 118462229 4525566 1532686..1533906 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1533906 4525566 MAV_1573 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_880807.1 1532686 D 243243 CDS YP_880808.1 118466503 4525586 1533908..1535107 1 NC_008595.1 L-carnitine dehydratase/bile acid-inducible protein F 1535107 4525586 MAV_1574 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_880808.1 1533908 D 243243 CDS YP_880809.1 118464909 4530744 1535130..1536323 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1536323 4530744 MAV_1575 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880809.1 1535130 D 243243 CDS YP_880810.1 118465289 4529325 1536330..1537022 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1537022 4529325 MAV_1576 Mycobacterium avium 104 GntR family transcriptional regulator YP_880810.1 1536330 D 243243 CDS YP_880811.1 118464872 4530708 1537097..1537459 1 NC_008595.1 hypothetical protein 1537459 4530708 MAV_1578 Mycobacterium avium 104 hypothetical protein YP_880811.1 1537097 D 243243 CDS YP_880812.1 118465751 4530443 complement(1537435..1538991) 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-binding enzyme 1538991 4530443 MAV_1577 Mycobacterium avium 104 AMP-binding enzyme YP_880812.1 1537435 R 243243 CDS YP_880813.1 118464624 4526781 complement(1538984..1540558) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA dehydrogenase 1540558 4526781 MAV_1579 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880813.1 1538984 R 243243 CDS YP_880814.1 118463898 4530575 complement(1540548..1542005) 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 1542005 4530575 MAV_1580 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_880814.1 1540548 R 243243 CDS YP_880815.1 118466593 4529359 complement(1542005..1542811) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1542811 4529359 MAV_1581 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880815.1 1542005 R 243243 CDS YP_880816.1 118463324 4529564 complement(1542802..1543614) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1543614 4529564 MAV_1582 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880816.1 1542802 R 243243 CDS YP_880817.1 118466737 4526338 complement(1543719..1544501) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1544501 4526338 MAV_1583 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880817.1 1543719 R 243243 CDS YP_880818.1 118463727 4528077 1544718..1545413 1 NC_008595.1 hypothetical protein 1545413 4528077 MAV_1584 Mycobacterium avium 104 hypothetical protein YP_880818.1 1544718 D 243243 CDS YP_880819.1 118464366 4530509 1545410..1546300 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1546300 4530509 MAV_1585 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_880819.1 1545410 D 243243 CDS YP_880820.1 118463695 4530582 complement(1546320..1547108) 1 NC_008595.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02909; TetR family transcriptional regulator 1547108 4530582 MAV_1586 Mycobacterium avium 104 TetR family transcriptional regulator YP_880820.1 1546320 R 243243 CDS YP_880821.1 118463438 4528318 1547304..1548101 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 1548101 4528318 MAV_1587 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_880821.1 1547304 D 243243 CDS YP_880822.1 118462370 4529182 1548146..1549162 1 NC_008595.1 identified by match to protein family HMM PF00701; dihydrodipicolinate synthetase 1549162 4529182 MAV_1588 Mycobacterium avium 104 dihydrodipicolinate synthetase YP_880822.1 1548146 D 243243 CDS YP_880823.1 118467137 4527150 complement(1549216..1549458) 1 NC_008595.1 hypothetical protein 1549458 4527150 MAV_1589 Mycobacterium avium 104 hypothetical protein YP_880823.1 1549216 R 243243 CDS YP_880824.1 118466575 4527364 1549770..1550594 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1550594 4527364 MAV_1590 Mycobacterium avium 104 enoyl-CoA hydratase YP_880824.1 1549770 D 243243 CDS YP_880825.1 118463801 4525883 1550614..1551816 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1551816 4525883 MAV_1591 Mycobacterium avium 104 amidohydrolase YP_880825.1 1550614 D 243243 CDS YP_880826.1 118465184 4528674 1551839..1553476 1 NC_008595.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 1553476 4528674 MAV_1592 Mycobacterium avium 104 acyl-CoA synthetase YP_880826.1 1551839 D 243243 CDS YP_880827.1 118466634 4526990 1553473..1554303 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1554303 4526990 MAV_1593 Mycobacterium avium 104 amidohydrolase YP_880827.1 1553473 D 243243 CDS YP_880828.1 118467302 4527261 1554306..1555352 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02771; acyl-CoA dehydrogenase 1555352 4527261 MAV_1594 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880828.1 1554306 D 243243 CDS YP_880829.1 118463577 4530732 1555353..1556546 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 1556546 4530732 MAV_1595 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880829.1 1555353 D 243243 CDS YP_880830.1 118463012 4526305 complement(1556663..1557808) 1 NC_008595.1 identified by match to protein family HMM PF02803; thiolase 1557808 4526305 MAV_1596 Mycobacterium avium 104 thiolase YP_880830.1 1556663 R 243243 CDS YP_880831.1 118465466 4526234 complement(1557863..1559077) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 1559077 4526234 MAV_1597 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_880831.1 1557863 R 243243 CDS YP_880832.1 118465042 4525821 complement(1559099..1560301) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1560301 4525821 MAV_1598 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880832.1 1559099 R 243243 CDS YP_880833.1 118465885 4527919 complement(1560430..1561272) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 1561272 4527919 MAV_1599 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_880833.1 1560430 R 243243 CDS YP_880834.1 118463313 4529553 complement(1561314..1562966) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 1562966 4529553 MAV_1600 Mycobacterium avium 104 acyl-CoA synthetase YP_880834.1 1561314 R 243243 CDS YP_880835.1 118462598 4528502 complement(1562975..1563607) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 1563607 4528502 MAV_1601 Mycobacterium avium 104 thioesterase YP_880835.1 1562975 R 243243 CDS YP_880836.1 118464712 4529399 complement(1563604..1564233) 1 NC_008595.1 identified by match to protein family HMM PF00857; isochorismatase 1564233 4529399 MAV_1602 Mycobacterium avium 104 isochorismatase YP_880836.1 1563604 R 243243 CDS YP_880837.1 118465390 4529682 complement(1564230..1565243) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 1565243 4529682 MAV_1603 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880837.1 1564230 R 243243 CDS YP_880838.1 118463615 4527562 1565360..1566982 1 NC_008595.1 steroid monooxygenase 1566982 4527562 MAV_1604 Mycobacterium avium 104 steroid monooxygenase YP_880838.1 1565360 D 243243 CDS YP_880839.1 118465740 4525703 1566997..1568118 1 NC_008595.1 hypothetical protein 1568118 4525703 MAV_1605 Mycobacterium avium 104 hypothetical protein YP_880839.1 1566997 D 243243 CDS YP_880840.1 118464339 4529141 1568118..1568498 1 NC_008595.1 hypothetical protein 1568498 4529141 MAV_1606 Mycobacterium avium 104 hypothetical protein YP_880840.1 1568118 D 243243 CDS YP_880841.1 118464526 4529446 1568507..1569535 1 NC_008595.1 hypothetical protein 1569535 4529446 MAV_1607 Mycobacterium avium 104 hypothetical protein YP_880841.1 1568507 D 243243 CDS YP_880842.1 118463967 4527213 complement(1569608..1571104) 1 NC_008595.1 identified by match to protein family HMM PF01039; carboxyl transferase domain-containing protein 1571104 4527213 MAV_1608 Mycobacterium avium 104 carboxyl transferase domain-containing protein YP_880842.1 1569608 R 243243 CDS YP_880843.1 118466496 4525579 1571271..1572506 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 family protein 1572506 4525579 MAV_1609 Mycobacterium avium 104 cytochrome P450 family protein YP_880843.1 1571271 D 243243 CDS YP_880844.1 118463332 4529202 1572564..1573388 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 1573388 4529202 MAV_1610 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_880844.1 1572564 D 243243 CDS YP_880845.1 118465372 4529233 1573464..1574081 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1574081 4529233 MAV_1611 Mycobacterium avium 104 TetR family transcriptional regulator YP_880845.1 1573464 D 243243 CDS YP_880846.1 118466882 4526701 1574105..1574782 1 NC_008595.1 hypothetical protein 1574782 4526701 MAV_1612 Mycobacterium avium 104 hypothetical protein YP_880846.1 1574105 D 243243 CDS YP_880847.1 118462599 4528503 1574786..1576690 1 NC_008595.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062; ABC transporter 1576690 4528503 MAV_1613 Mycobacterium avium 104 ABC transporter YP_880847.1 1574786 D 243243 CDS YP_880848.1 118467012 4529482 complement(1576698..1577855) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase B 1577855 4529482 MAV_1614 Mycobacterium avium 104 alcohol dehydrogenase B YP_880848.1 1576698 R 243243 CDS YP_880849.1 118464732 4529419 complement(1577852..1579084) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1579084 4529419 MAV_1615 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880849.1 1577852 R 243243 CDS YP_880850.1 118462536 4527679 1579378..1580337 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 1580337 4527679 MAV_1617 Mycobacterium avium 104 alpha/beta hydrolase YP_880850.1 1579378 D 243243 CDS YP_880851.1 118464852 4527968 complement(1580314..1580511) 1 NC_008595.1 hypothetical protein 1580511 4527968 MAV_1616 Mycobacterium avium 104 hypothetical protein YP_880851.1 1580314 R 243243 CDS YP_880852.1 118465518 4528935 1580551..1581699 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 1581699 4528935 MAV_1618 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880852.1 1580551 D 243243 CDS YP_880853.1 118464019 4528815 1581696..1582937 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase middle domain-containing protein 1582937 4528815 MAV_1620 Mycobacterium avium 104 acyl-CoA dehydrogenase middle domain-containing protein YP_880853.1 1581696 D 243243 CDS YP_880854.1 118466995 4529522 complement(1582934..1584901) 1 NC_008595.1 identified by match to protein family HMM PF01740; match to protein family HMM PF02518; match to protein family HMM PF07228; anti-anti-sigma factor 1584901 4529522 MAV_1619 Mycobacterium avium 104 anti-anti-sigma factor YP_880854.1 1582934 R 243243 CDS YP_880855.1 118464859 4530695 1585148..1585657 1 NC_008595.1 hypothetical protein 1585657 4530695 MAV_1621 Mycobacterium avium 104 hypothetical protein YP_880855.1 1585148 D 243243 CDS YP_880856.1 118462583 4530203 1585671..1587161 1 NC_008595.1 identified by match to protein family HMM PF00174; oxidoreductase molybdopterin binding subunit 1587161 4530203 MAV_1622 Mycobacterium avium 104 oxidoreductase molybdopterin binding subunit YP_880856.1 1585671 D 243243 CDS YP_880857.1 118464130 4528831 1587163..1587465 1 NC_008595.1 hypothetical protein 1587465 4528831 MAV_1624 Mycobacterium avium 104 hypothetical protein YP_880857.1 1587163 D 243243 CDS YP_880858.1 118463281 4530529 complement(1587410..1587781) 1 NC_008595.1 hypothetical protein 1587781 4530529 MAV_1623 Mycobacterium avium 104 hypothetical protein YP_880858.1 1587410 R 243243 CDS YP_880859.1 118465595 4527143 complement(1587843..1589051) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1589051 4527143 MAV_1625 Mycobacterium avium 104 amidohydrolase YP_880859.1 1587843 R 243243 CDS YP_880860.1 118462839 4528654 complement(1589151..1590182) 1 NC_008595.1 identified by match to protein family HMM PF00440; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1590182 4528654 MAV_1626 Mycobacterium avium 104 hypothetical protein YP_880860.1 1589151 R 243243 CDS YP_880861.1 118464772 4529127 complement(1590275..1591771) 1 NC_008595.1 identified by match to protein family HMM PF00501; feruloyl-CoA synthetase 1591771 4529127 MAV_1627 Mycobacterium avium 104 feruloyl-CoA synthetase YP_880861.1 1590275 R 243243 CDS YP_880862.1 118463361 4529895 complement(1591768..1592703) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1592703 4529895 MAV_1628 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880862.1 1591768 R 243243 CDS YP_880863.1 118466384 4526185 complement(1592700..1593848) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 1593848 4526185 MAV_1629 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880863.1 1592700 R 243243 CDS YP_880864.1 118467167 4527599 complement(1593854..1594951) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 1594951 4527599 MAV_1630 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880864.1 1593854 R 243243 CDS YP_880865.1 118462397 4525941 complement(1594978..1596048) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1596048 4525941 MAV_1631 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880865.1 1594978 R 243243 CDS YP_880866.1 118463103 4527165 1596128..1596979 1 NC_008595.1 hypothetical protein 1596979 4527165 MAV_1632 Mycobacterium avium 104 hypothetical protein YP_880866.1 1596128 D 243243 CDS YP_880867.1 118465823 4525926 complement(1596983..1597699) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 1597699 4525926 MAV_1633 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_880867.1 1596983 R 243243 CDS YP_880868.1 118462558 4528617 complement(1597719..1598540) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1598540 4528617 MAV_1634 Mycobacterium avium 104 GntR family transcriptional regulator YP_880868.1 1597719 R 243243 CDS YP_880869.1 118463297 4525992 1598636..1601056 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 1601056 4525992 MAV_1635 Mycobacterium avium 104 caib/baif family protein YP_880869.1 1598636 D 243243 CDS YP_880870.1 118466576 4527366 1601076..1601267 1 NC_008595.1 hypothetical protein 1601267 4527366 MAV_1636 Mycobacterium avium 104 hypothetical protein YP_880870.1 1601076 D 243243 CDS YP_880871.1 118467232 4529789 complement(1601269..1602564) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1602564 4529789 MAV_1637 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_880871.1 1601269 R 243243 CDS YP_880872.1 118464972 4528712 1602661..1603788 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 1603788 4528712 MAV_1638 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880872.1 1602661 D 243243 CDS YP_880873.1 118465738 4525701 1603788..1605353 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-binding enzyme, putative 1605353 4525701 MAV_1639 Mycobacterium avium 104 AMP-binding enzyme, putative YP_880873.1 1603788 D 243243 CDS YP_880874.1 118463558 4526825 1605415..1605840 1 NC_008595.1 hypothetical protein 1605840 4526825 MAV_1640 Mycobacterium avium 104 hypothetical protein YP_880874.1 1605415 D 243243 CDS YP_880875.1 118463852 4529951 1605854..1606384 1 NC_008595.1 hypothetical protein 1606384 4529951 MAV_1641 Mycobacterium avium 104 hypothetical protein YP_880875.1 1605854 D 243243 CDS YP_880876.1 118462439 4528302 1606396..1606818 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC like domain-containing protein 1606818 4528302 MAV_1642 Mycobacterium avium 104 MaoC like domain-containing protein YP_880876.1 1606396 D 243243 CDS YP_880877.1 118462843 4526025 complement(1606888..1608354) 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1608354 4526025 MAV_1643 Mycobacterium avium 104 aldehyde dehydrogenase YP_880877.1 1606888 R 243243 CDS YP_880878.1 118465344 4526657 1608486..1609838 1 NC_008595.1 hypothetical protein 1609838 4526657 MAV_1645 Mycobacterium avium 104 hypothetical protein YP_880878.1 1608486 D 243243 CDS YP_880879.1 118463496 4529075 complement(1609827..1610972) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 1610972 4529075 MAV_1644 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_880879.1 1609827 R 243243 CDS YP_880880.1 118467158 4527589 1611013..1611921 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1611921 4527589 MAV_1646 Mycobacterium avium 104 MerR family transcriptional regulator YP_880880.1 1611013 D 243243 CDS YP_880881.1 118464458 4527051 1611982..1612704 1 NC_008595.1 identified by match to protein family HMM TIGR01409; secreted protein 1612704 4527051 MAV_1648 Mycobacterium avium 104 secreted protein YP_880881.1 1611982 D 243243 CDS YP_880882.1 118466841 4526950 complement(1612701..1613006) 1 NC_008595.1 hypothetical protein 1613006 4526950 MAV_1647 Mycobacterium avium 104 hypothetical protein YP_880882.1 1612701 R 243243 CDS YP_880883.1 118465839 4525511 complement(1613026..1613139) 1 NC_008595.1 hypothetical protein 1613139 4525511 MAV_1649 Mycobacterium avium 104 hypothetical protein YP_880883.1 1613026 R 243243 CDS YP_880884.1 118464761 4527657 1613268..1622546 1 NC_008595.1 identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801; fatty acid synthase 1622546 4527657 MAV_1650 Mycobacterium avium 104 fatty acid synthase YP_880884.1 1613268 D 243243 CDS YP_880885.1 118463013 4526306 1622590..1622967 1 NC_008595.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1622967 acpS 4526306 acpS Mycobacterium avium 104 4'-phosphopantetheinyl transferase YP_880885.1 1622590 D 243243 CDS YP_880886.1 118462467 4528721 1623045..1624385 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; hypothetical protein 1624385 4528721 MAV_1652 Mycobacterium avium 104 hypothetical protein YP_880886.1 1623045 D 243243 CDS YP_880887.1 118467041 4526497 complement(1624386..1624859) 1 NC_008595.1 identified by match to protein family HMM PF00578; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1624859 4526497 MAV_1653 Mycobacterium avium 104 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_880887.1 1624386 R 243243 CDS YP_880888.1 118466181 4526212 1624964..1625191 1 NC_008595.1 hypothetical protein 1625191 4526212 MAV_1655 Mycobacterium avium 104 hypothetical protein YP_880888.1 1624964 D 243243 CDS YP_880889.1 118462498 4530694 complement(1625178..1626917) 1 NC_008595.1 hypothetical protein 1626917 4530694 MAV_1654 Mycobacterium avium 104 hypothetical protein YP_880889.1 1625178 R 243243 CDS YP_880890.1 118465636 4526161 complement(1627056..1627322) 1 NC_008595.1 hypothetical protein 1627322 4526161 MAV_1656 Mycobacterium avium 104 hypothetical protein YP_880890.1 1627056 R 243243 CDS YP_880891.1 118465052 4527028 complement(1627699..1628937) 1 NC_008595.1 hypothetical protein 1628937 4527028 MAV_1658 Mycobacterium avium 104 hypothetical protein YP_880891.1 1627699 R 243243 CDS YP_880892.1 118463097 4528920 1629127..1631481 1 NC_008595.1 identified by match to protein family HMM PF03176; mmpl family protein 1631481 4528920 MAV_1659 Mycobacterium avium 104 mmpl family protein YP_880892.1 1629127 D 243243 CDS YP_880893.1 118462410 4525720 1631529..1632422 1 NC_008595.1 hypothetical protein 1632422 4525720 MAV_1660 Mycobacterium avium 104 hypothetical protein YP_880893.1 1631529 D 243243 CDS YP_880894.1 118467259 4526094 1632641..1633780 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 1633780 4526094 MAV_1661 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_880894.1 1632641 D 243243 CDS YP_880895.1 118466415 4530159 complement(1633788..1634213) 1 NC_008595.1 hypothetical protein 1634213 4530159 MAV_1662 Mycobacterium avium 104 hypothetical protein YP_880895.1 1633788 R 243243 CDS YP_880896.1 118464888 4529617 complement(1634423..1635070) 1 NC_008595.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1635070 4529617 MAV_1664 Mycobacterium avium 104 oligoribonuclease YP_880896.1 1634423 R 243243 CDS YP_880897.1 118465438 4527307 1635196..1636761 1 NC_008595.1 identified by match to protein family HMM PF05872; ATP-binding protein 1636761 4527307 MAV_1665 Mycobacterium avium 104 ATP-binding protein YP_880897.1 1635196 D 243243 CDS YP_880898.1 118463756 4528000 complement(1636765..1637571) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1637571 4528000 MAV_1666 Mycobacterium avium 104 short chain dehydrogenase YP_880898.1 1636765 R 243243 CDS YP_880899.1 118467009 4529479 1637686..1638981 1 NC_008595.1 identified by match to protein family HMM PF07690; permease of the major facilitator superfamily protein 1638981 4529479 MAV_1667 Mycobacterium avium 104 permease of the major facilitator superfamily protein YP_880899.1 1637686 D 243243 CDS YP_880900.1 118464794 4526718 complement(1639088..1639849) 1 NC_008595.1 hypothetical protein 1639849 4526718 MAV_1668 Mycobacterium avium 104 hypothetical protein YP_880900.1 1639088 R 243243 CDS YP_880901.1 118462743 4527814 complement(1639913..1640506) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1640506 4527814 MAV_1669 Mycobacterium avium 104 TetR family transcriptional regulator YP_880901.1 1639913 R 243243 CDS YP_880902.1 118465058 4527034 1640752..1642353 1 NC_008595.1 identified by match to protein family HMM PF01039; carboxyl transferase 1642353 4527034 MAV_1670 Mycobacterium avium 104 carboxyl transferase YP_880902.1 1640752 D 243243 CDS YP_880903.1 118465868 4527510 1642359..1644374 1 NC_008595.1 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; acetyl-/propionyl-coenzyme A carboxylase alpha chain 1644374 4527510 MAV_1671 Mycobacterium avium 104 acetyl-/propionyl-coenzyme A carboxylase alpha chain YP_880903.1 1642359 D 243243 CDS YP_880904.1 118466232 4526578 1644371..1645537 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1645537 4526578 MAV_1672 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_880904.1 1644371 D 243243 CDS YP_880905.1 118466716 4529723 1645534..1646034 1 NC_008595.1 identified by match to protein family HMM PF01575; MoaC domain-containing protein 1646034 4529723 MAV_1673 Mycobacterium avium 104 MoaC domain-containing protein YP_880905.1 1645534 D 243243 CDS YP_880906.1 118462754 4527844 1646031..1646852 1 NC_008595.1 identified by match to protein family HMM PF03328; CitE protein 1646852 4527844 MAV_1674 Mycobacterium avium 104 CitE protein YP_880906.1 1646031 D 243243 CDS YP_880907.1 118466239 4526585 1647037..1648128 1 NC_008595.1 identified by match to protein family HMM PF00676; pyruvate dehydrogenase E1 component, alpha subunit 1648128 4526585 MAV_1675 Mycobacterium avium 104 pyruvate dehydrogenase E1 component, alpha subunit YP_880907.1 1647037 D 243243 CDS YP_880908.1 118463912 4525843 1648132..1649187 1 NC_008595.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase E1 component subunit beta 1649187 4525843 MAV_1676 Mycobacterium avium 104 pyruvate dehydrogenase E1 component subunit beta YP_880908.1 1648132 D 243243 CDS YP_880909.1 118462619 4526421 1649184..1650350 1 NC_008595.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; branched-chain alpha-keto acid dehydrogenase subunit E2 1650350 4526421 MAV_1677 Mycobacterium avium 104 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_880909.1 1649184 D 243243 CDS YP_880910.1 118463318 4529558 complement(1650353..1651123) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1651123 4529558 MAV_1678 Mycobacterium avium 104 enoyl-CoA hydratase YP_880910.1 1650353 R 243243 CDS YP_880911.1 118464104 4525865 complement(1651373..1651783) 1 NC_008595.1 hypothetical protein 1651783 4525865 MAV_1679 Mycobacterium avium 104 hypothetical protein YP_880911.1 1651373 R 243243 CDS YP_880912.1 118464055 4529495 complement(1651994..1652911) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1652911 4529495 MAV_1680 Mycobacterium avium 104 transposase YP_880912.1 1651994 R 243243 CDS YP_880913.1 118464738 4529425 complement(1652911..1653186) 1 NC_008595.1 transposase 1653186 4529425 MAV_1681 Mycobacterium avium 104 transposase YP_880913.1 1652911 R 243243 CDS YP_880914.1 118464823 4529725 complement(1653447..1654106) 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase cutinase 1654106 4529725 MAV_1682 Mycobacterium avium 104 serine esterase cutinase YP_880914.1 1653447 R 243243 CDS YP_880915.1 118465670 4526742 1654829..1655137 1 NC_008595.1 hypothetical protein 1655137 4526742 MAV_1683 Mycobacterium avium 104 hypothetical protein YP_880915.1 1654829 D 243243 CDS YP_880916.1 118462652 4529393 1655721..1656968 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 1656968 4529393 MAV_1685 Mycobacterium avium 104 alpha/beta hydrolase YP_880916.1 1655721 D 243243 CDS YP_880917.1 118463221 4528795 1657126..1658601 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 1658601 4528795 MAV_1686 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_880917.1 1657126 D 243243 CDS YP_880918.1 118464146 4526455 1658664..1660415 1 NC_008595.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; acyltransferase 1660415 4526455 MAV_1687 Mycobacterium avium 104 acyltransferase YP_880918.1 1658664 D 243243 CDS YP_880919.1 118463277 4530525 1661600..1661944 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 1661944 4530525 MAV_1689 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_880919.1 1661600 D 243243 CDS YP_880920.1 118462656 4529084 1662022..1662861 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1662861 4529084 MAV_1690 Mycobacterium avium 104 transposase YP_880920.1 1662022 D 243243 CDS YP_880921.1 118465739 4525702 1664145..1666214 1 NC_008595.1 identified by match to protein family HMM PF05425; ABC transporter permease 1666214 4525702 MAV_1692 Mycobacterium avium 104 ABC transporter permease YP_880921.1 1664145 D 243243 CDS YP_880922.1 118466586 4527376 1666214..1666351 1 NC_008595.1 hypothetical protein 1666351 4527376 MAV_1693 Mycobacterium avium 104 hypothetical protein YP_880922.1 1666214 D 243243 CDS YP_880923.1 118465023 4530072 1666414..1666896 1 NC_008595.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; hypothetical protein 1666896 ssb 4530072 ssb Mycobacterium avium 104 hypothetical protein YP_880923.1 1666414 D 243243 CDS YP_880924.1 118464295 4529583 1666975..1668651 1 NC_008595.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1668651 4529583 MAV_1695 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_880924.1 1666975 D 243243 CDS YP_880925.1 118462883 4527489 1668685..1673583 1 NC_008595.1 identified by match to protein family HMM PF05088; NAD-glutamate dehydrogenase 1673583 4527489 MAV_1696 Mycobacterium avium 104 NAD-glutamate dehydrogenase YP_880925.1 1668685 D 243243 CDS YP_880926.1 118462297 4525642 1673580..1673993 1 NC_008595.1 hypothetical protein 1673993 4525642 MAV_1697 Mycobacterium avium 104 hypothetical protein YP_880926.1 1673580 D 243243 CDS YP_880927.1 118462730 4527801 1673981..1674652 1 NC_008595.1 hypothetical protein 1674652 4527801 MAV_1698 Mycobacterium avium 104 hypothetical protein YP_880927.1 1673981 D 243243 CDS YP_880928.1 118467294 4527252 complement(1674723..1675733) 1 NC_008595.1 hypothetical protein 1675733 4527252 MAV_1699 Mycobacterium avium 104 hypothetical protein YP_880928.1 1674723 R 243243 CDS YP_880929.1 118466250 4526869 complement(1675806..1677422) 1 NC_008595.1 identified by match to protein family HMM PF00128; alpha-amylase 1677422 4526869 MAV_1700 Mycobacterium avium 104 alpha-amylase YP_880929.1 1675806 R 243243 CDS YP_880930.1 118465854 4530648 complement(1677419..1677808) 1 NC_008595.1 identified by match to protein family HMM PF01152; hypothetical protein 1677808 4530648 MAV_1701 Mycobacterium avium 104 hypothetical protein YP_880930.1 1677419 R 243243 CDS YP_880931.1 118464205 4526885 1677952..1678599 1 NC_008595.1 identified by match to protein family HMM PF01844; HNH endonuclease 1678599 4526885 MAV_1702 Mycobacterium avium 104 HNH endonuclease YP_880931.1 1677952 D 243243 CDS YP_880932.1 118463696 4530583 1678665..1678895 1 NC_008595.1 hypothetical protein 1678895 4530583 MAV_1703 Mycobacterium avium 104 hypothetical protein YP_880932.1 1678665 D 243243 CDS YP_880933.1 118464027 4528823 1678882..1679349 1 NC_008595.1 hypothetical protein 1679349 4528823 MAV_1705 Mycobacterium avium 104 hypothetical protein YP_880933.1 1678882 D 243243 CDS YP_880934.1 118462256 4526399 complement(1679346..1681937) 1 NC_008595.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02412; aminopeptidase N 1681937 pepN 4526399 pepN Mycobacterium avium 104 aminopeptidase N YP_880934.1 1679346 R 243243 CDS YP_880935.1 118467334 4526972 1682045..1682668 1 NC_008595.1 identified by match to protein family HMM PF01323; hypothetical protein 1682668 4526972 MAV_1706 Mycobacterium avium 104 hypothetical protein YP_880935.1 1682045 D 243243 CDS YP_880936.1 118466601 4529367 1682724..1683203 1 NC_008595.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1683203 4529367 MAV_1707 Mycobacterium avium 104 ribose-5-phosphate isomerase B YP_880936.1 1682724 D 243243 CDS YP_880937.1 118465909 4528991 1683222..1684028 1 NC_008595.1 identified by match to protein family HMM PF01149; match to protein family HMM PF06831; endonuclease VIII and DNA n-glycosylase with an AP lyase activity 1684028 4528991 MAV_1708 Mycobacterium avium 104 endonuclease VIII and DNA n-glycosylase with an AP lyase activity YP_880937.1 1683222 D 243243 CDS YP_880938.1 118464021 4528817 complement(1684482..1685672) 1 NC_008595.1 identified by similarity to PIR:JC2091; match to protein family HMM PF00144; carboxylesterase, putative 1685672 lipP 4528817 lipP Mycobacterium avium 104 carboxylesterase, putative YP_880938.1 1684482 R 243243 CDS YP_880939.1 118463791 4525872 1686069..1687463 1 NC_008595.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1687463 tig 4525872 tig Mycobacterium avium 104 trigger factor YP_880939.1 1686069 D 243243 CDS YP_880940.1 118462557 4528616 1687584..1688183 1 NC_008595.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1688183 clpP 4528616 clpP Mycobacterium avium 104 ATP-dependent Clp protease proteolytic subunit YP_880940.1 1687584 D 243243 CDS YP_880941.1 118462339 4525684 1688180..1688815 1 NC_008595.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1688815 clpP 4525684 clpP Mycobacterium avium 104 ATP-dependent Clp protease proteolytic subunit YP_880941.1 1688180 D 243243 CDS YP_880942.1 118466904 4528418 complement(1688837..1689712) 1 NC_008595.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 1689712 mmuM 4528418 mmuM Mycobacterium avium 104 homocysteine methyltransferase YP_880942.1 1688837 R 243243 CDS YP_880943.1 118466554 4529103 1690046..1691326 1 NC_008595.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1691326 clpX 4529103 clpX Mycobacterium avium 104 ATP-dependent protease ATP-binding subunit ClpX YP_880943.1 1690046 D 243243 CDS YP_880944.1 118466031 4529918 1691598..1693568 1 NC_008595.1 identified by match to protein family HMM PF01855; pyruvate synthase 1693568 4529918 MAV_1717 Mycobacterium avium 104 pyruvate synthase YP_880944.1 1691598 D 243243 CDS YP_880945.1 118465140 4529172 1693626..1694717 1 NC_008595.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1694717 orB 4529172 orB Mycobacterium avium 104 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_880945.1 1693626 D 243243 CDS YP_880946.1 118464652 4528249 1694719..1695312 1 NC_008595.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 1695312 4528249 MAV_1719 Mycobacterium avium 104 molybdopterin-guanine dinucleotide biosynthesis protein A YP_880946.1 1694719 D 243243 CDS YP_880947.1 118462499 4528577 1695475..1695645 1 NC_008595.1 hypothetical protein 1695645 4528577 MAV_1720 Mycobacterium avium 104 hypothetical protein YP_880947.1 1695475 D 243243 CDS YP_880948.1 118463372 4528950 complement(1696025..1696405) 1 NC_008595.1 hypothetical protein 1696405 4528950 MAV_1721 Mycobacterium avium 104 hypothetical protein YP_880948.1 1696025 R 243243 CDS YP_880949.1 118466908 4529452 1696421..1696861 1 NC_008595.1 identified by match to protein family HMM PF06737; secreted protein 1696861 4529452 MAV_1722 Mycobacterium avium 104 secreted protein YP_880949.1 1696421 D 243243 CDS YP_880950.1 118462668 4529096 1696931..1698190 1 NC_008595.1 identified by match to protein family HMM PF03435; saccharopine dehydrogenase 1698190 4529096 MAV_1723 Mycobacterium avium 104 saccharopine dehydrogenase YP_880950.1 1696931 D 243243 CDS YP_880951.1 118463457 4529699 1698249..1700897 1 NC_008595.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1700897 valS 4529699 valS Mycobacterium avium 104 valyl-tRNA synthetase YP_880951.1 1698249 D 243243 CDS YP_880952.1 118464061 4529501 1700894..1702351 1 NC_008595.1 identified by match to protein family HMM PF02875; match to protein family HMM TIGR01499; FolC protein 1702351 4529501 MAV_1725 Mycobacterium avium 104 FolC protein YP_880952.1 1700894 D 243243 CDS YP_880953.1 118463661 4525953 1702348..1702725 1 NC_008595.1 hypothetical protein 1702725 4525953 MAV_1726 Mycobacterium avium 104 hypothetical protein YP_880953.1 1702348 D 243243 CDS YP_880954.1 118464230 4528603 1702766..1703176 1 NC_008595.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1703176 ndk 4528603 ndk Mycobacterium avium 104 nucleoside diphosphate kinase YP_880954.1 1702766 D 243243 CDS YP_880955.1 118465085 4525902 1703516..1706365 1 NC_008595.1 identified by match to protein family HMM PF00575; match to protein family HMM TIGR00757; Rne protein 1706365 4525902 MAV_1728 Mycobacterium avium 104 Rne protein YP_880955.1 1703516 D 243243 CDS YP_880956.1 118465878 4527520 1706576..1706887 1 NC_008595.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1706887 rplU 4527520 rplU Mycobacterium avium 104 50S ribosomal protein L21 YP_880956.1 1706576 D 243243 CDS YP_880957.1 118465691 4525750 1706905..1707171 1 NC_008595.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1707171 rpmA 4525750 rpmA Mycobacterium avium 104 50S ribosomal protein L27 YP_880957.1 1706905 D 243243 CDS YP_880958.1 118466067 4530037 1707262..1708740 1 NC_008595.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1708740 obgE 4530037 obgE Mycobacterium avium 104 GTPase ObgE YP_880958.1 1707262 D 243243 CDS YP_880959.1 118462555 4530556 1708737..1709840 1 NC_008595.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1709840 proB 4530556 proB Mycobacterium avium 104 gamma-glutamyl kinase YP_880959.1 1708737 D 243243 CDS YP_880960.1 118466300 4529547 complement(1709855..1710505) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1710505 4529547 MAV_1733 Mycobacterium avium 104 TetR family transcriptional regulator YP_880960.1 1709855 R 243243 CDS YP_880961.1 118466959 4530271 1710610..1711887 1 NC_008595.1 cytochrome P450 124 1711887 4530271 MAV_1734 Mycobacterium avium 104 cytochrome P450 124 YP_880961.1 1710610 D 243243 CDS YP_880962.1 118464883 4529612 complement(1711899..1712747) 1 NC_008595.1 identified by match to protein family HMM PF02146; NAD-dependent deacetylase 1 1712747 4529612 MAV_1735 Mycobacterium avium 104 NAD-dependent deacetylase 1 YP_880962.1 1711899 R 243243 CDS YP_880963.1 118465526 4528944 complement(1712765..1713292) 1 NC_008595.1 identified by match to protein family HMM PF00857; isochorismatase 1713292 4528944 MAV_1736 Mycobacterium avium 104 isochorismatase YP_880963.1 1712765 R 243243 CDS YP_880964.1 118464022 4528818 1713367..1715409 1 NC_008595.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1715409 nadE 4528818 nadE Mycobacterium avium 104 NAD synthetase YP_880964.1 1713367 D 243243 CDS YP_880965.1 118464528 4529448 complement(1715458..1715865) 1 NC_008595.1 hypothetical protein 1715865 4529448 MAV_1738 Mycobacterium avium 104 hypothetical protein YP_880965.1 1715458 R 243243 CDS YP_880966.1 118462798 4525767 complement(1716005..1716574) 1 NC_008595.1 identified by match to protein family HMM PF00694; match to protein family HMM TIGR02087; 3-isopropylmalate dehydratase small subunit 1716574 4525767 MAV_1739 Mycobacterium avium 104 3-isopropylmalate dehydratase small subunit YP_880966.1 1716005 R 243243 CDS YP_880967.1 118466254 4526873 complement(1716571..1717812) 1 NC_008595.1 identified by match to protein family HMM PF00330; match to protein family HMM TIGR01343; 3-isopropylmalate dehydratase large subunit 1717812 4526873 MAV_1740 Mycobacterium avium 104 3-isopropylmalate dehydratase large subunit YP_880967.1 1716571 R 243243 CDS YP_880968.1 118466464 4528686 complement(1718707..1720137) 1 NC_008595.1 identified by match to protein family HMM PF03972; MmgE/PrpD family protein 1720137 4528686 MAV_1742 Mycobacterium avium 104 MmgE/PrpD family protein YP_880968.1 1718707 R 243243 CDS YP_880969.1 118463352 4529886 1720229..1721032 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1721032 4529886 MAV_1744 Mycobacterium avium 104 GntR family transcriptional regulator YP_880969.1 1720229 D 243243 CDS YP_880970.1 118463956 4526608 complement(1721029..1721880) 1 NC_008595.1 identified by match to protein family HMM PF00294; kinase, pfkB family protein 1721880 4526608 MAV_1743 Mycobacterium avium 104 kinase, pfkB family protein YP_880970.1 1721029 R 243243 CDS YP_880971.1 118464838 4529743 1722065..1724260 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF00672; adenylate and guanylate cyclase catalytic domain-containing protein 1724260 4529743 MAV_1745 Mycobacterium avium 104 adenylate and guanylate cyclase catalytic domain-containing protein YP_880971.1 1722065 D 243243 CDS YP_880972.1 118466394 4526195 1725729..1727036 1 NC_008595.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1727036 proA 4526195 proA Mycobacterium avium 104 gamma-glutamyl phosphate reductase YP_880972.1 1725729 D 243243 CDS YP_880973.1 118466932 4527767 1727070..1727945 1 NC_008595.1 identified by match to protein family HMM PF07728; ATPase 1727945 4527767 MAV_1748 Mycobacterium avium 104 ATPase YP_880973.1 1727070 D 243243 CDS YP_880974.1 118462667 4529095 1727956..1729404 1 NC_008595.1 identified by match to protein family HMM PF05762; hypothetical protein 1729404 4529095 MAV_1749 Mycobacterium avium 104 hypothetical protein YP_880974.1 1727956 D 243243 CDS YP_880975.1 118463368 4528946 1729565..1730206 1 NC_008595.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1730206 nadD 4528946 nadD Mycobacterium avium 104 nicotinic acid mononucleotide adenylyltransferase YP_880975.1 1729565 D 243243 CDS YP_880976.1 118463750 4527994 1730203..1730598 1 NC_008595.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein 1730598 4527994 MAV_1751 Mycobacterium avium 104 hypothetical protein YP_880976.1 1730203 D 243243 CDS YP_880977.1 118464523 4529443 1730595..1731269 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 1731269 4529443 MAV_1752 Mycobacterium avium 104 phosphoglycerate mutase YP_880977.1 1730595 D 243243 CDS YP_880978.1 118463634 4527338 1731259..1732008 1 NC_008595.1 hypothetical protein 1732008 4527338 MAV_1753 Mycobacterium avium 104 hypothetical protein YP_880978.1 1731259 D 243243 CDS YP_880979.1 118464386 4528275 1732017..1732850 1 NC_008595.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; DegV family protein 1732850 4528275 MAV_1754 Mycobacterium avium 104 DegV family protein YP_880979.1 1732017 D 243243 CDS YP_880980.1 118466765 4530760 complement(1732860..1735766) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL4 protein 1735766 4530760 MAV_1755 Mycobacterium avium 104 MmpL4 protein YP_880980.1 1732860 R 243243 CDS YP_880981.1 118464951 4528213 complement(1735763..1736155) 1 NC_008595.1 identified by match to protein family HMM PF05423; Mmps1 protein 1736155 4528213 MAV_1756 Mycobacterium avium 104 Mmps1 protein YP_880981.1 1735763 R 243243 CDS YP_880982.1 118463978 4530336 complement(1736332..1737417) 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 1737417 dapB 4530336 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_880982.1 1736332 R 243243 CDS YP_880983.1 118463397 4528024 complement(1737454..1738104) 1 NC_008595.1 hypothetical protein 1738104 4528024 MAV_1758 Mycobacterium avium 104 hypothetical protein YP_880983.1 1737454 R 243243 CDS YP_880984.1 118466517 4527190 complement(1738145..1739857) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 1739857 4527190 MAV_1759 Mycobacterium avium 104 acyl-CoA synthetase YP_880984.1 1738145 R 243243 CDS YP_880985.1 118462506 4528584 complement(1739930..1741060) 1 NC_008595.1 hypothetical protein 1741060 4528584 MAV_1760 Mycobacterium avium 104 hypothetical protein YP_880985.1 1739930 R 243243 CDS YP_880986.1 118465611 4527870 complement(1741101..1744145) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL10 protein 1744145 4527870 MAV_1761 Mycobacterium avium 104 MmpL10 protein YP_880986.1 1741101 R 243243 CDS YP_880987.1 118463607 4527554 complement(1744228..1745649) 1 NC_008595.1 identified by match to protein family HMM PF00668; condensation domain-containing protein 1745649 4527554 MAV_1762 Mycobacterium avium 104 condensation domain-containing protein YP_880987.1 1744228 R 243243 CDS YP_880988.1 118466712 4529719 1746555..1757594 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; tylactone synthase modules 4 & 5 1757594 4529719 MAV_1763 Mycobacterium avium 104 tylactone synthase modules 4 & 5 YP_880988.1 1746555 D 243243 CDS YP_880989.1 118467253 4526088 complement(1757608..1758030) 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 1758030 4526088 MAV_1764 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_880989.1 1757608 R 243243 CDS YP_880990.1 118464845 4527961 complement(1758035..1759141) 1 NC_008595.1 identified by match to protein family HMM PF00441; pimeloyl-CoA dehydrogenase 1759141 4527961 MAV_1765 Mycobacterium avium 104 pimeloyl-CoA dehydrogenase YP_880990.1 1758035 R 243243 CDS YP_880991.1 118466996 4529524 complement(1759149..1760309) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase domain-containing protein 1760309 4529524 MAV_1766 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_880991.1 1759149 R 243243 CDS YP_880992.1 118466311 4528353 1760489..1761349 1 NC_008595.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; competence protein ComEA 1761349 4528353 MAV_1767 Mycobacterium avium 104 competence protein ComEA YP_880992.1 1760489 D 243243 CDS YP_880993.1 118463280 4530528 1761394..1762896 1 NC_008595.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; competence protein 1762896 4530528 MAV_1768 Mycobacterium avium 104 competence protein YP_880993.1 1761394 D 243243 CDS YP_880994.1 118462813 4529033 1762956..1763933 1 NC_008595.1 identified by match to protein family HMM PF06144; hypothetical protein 1763933 4529033 MAV_1769 Mycobacterium avium 104 hypothetical protein YP_880994.1 1762956 D 243243 CDS YP_880995.1 118464716 4529403 complement(1763944..1764204) 1 NC_008595.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1764204 rpsT 4529403 rpsT Mycobacterium avium 104 30S ribosomal protein S20 YP_880995.1 1763944 R 243243 CDS YP_880996.1 118463027 4528868 1766024..1767001 1 NC_008595.1 identified by match to protein family HMM PF04168; hypothetical protein 1767001 4528868 MAV_1772 Mycobacterium avium 104 hypothetical protein YP_880996.1 1766024 D 243243 CDS YP_880997.1 118462490 4530686 1767001..1768053 1 NC_008595.1 identified by match to protein family HMM PF01841; hypothetical protein 1768053 4530686 MAV_1773 Mycobacterium avium 104 hypothetical protein YP_880997.1 1767001 D 243243 CDS YP_880998.1 118464571 4530275 1768011..1768571 1 NC_008595.1 hypothetical protein 1768571 4530275 MAV_1775 Mycobacterium avium 104 hypothetical protein YP_880998.1 1768011 D 243243 CDS YP_880999.1 118466889 4528402 complement(1768550..1769392) 1 NC_008595.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1769392 4528402 MAV_1774 Mycobacterium avium 104 ribonuclease Z YP_880999.1 1768550 R 243243 CDS YP_881000.1 118466251 4526870 1769520..1769948 1 NC_008595.1 identified by match to protein family HMM PF00571; CBS domain-containing protein 1769948 4526870 MAV_1776 Mycobacterium avium 104 CBS domain-containing protein YP_881000.1 1769520 D 243243 CDS YP_881001.1 118465524 4528942 complement(1769977..1770579) 1 NC_008595.1 hypothetical protein 1770579 4528942 MAV_1777 Mycobacterium avium 104 hypothetical protein YP_881001.1 1769977 R 243243 CDS YP_881002.1 118465440 4527309 1770604..1772538 1 NC_008595.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1772538 lepA 4527309 lepA Mycobacterium avium 104 GTP-binding protein LepA YP_881002.1 1770604 D 243243 CDS YP_881003.1 118464267 4528222 1772553..1773311 1 NC_008595.1 LppR protein 1773311 4528222 MAV_1779 Mycobacterium avium 104 LppR protein YP_881003.1 1772553 D 243243 CDS YP_881004.1 118463965 4527211 complement(1773324..1775363) 1 NC_008595.1 identified by match to protein family HMM PF00723; glycoside hydrolase 1775363 4527211 MAV_1780 Mycobacterium avium 104 glycoside hydrolase YP_881004.1 1773324 R 243243 CDS YP_881005.1 118463346 4529216 1775525..1775719 1 NC_008595.1 hypothetical protein 1775719 4529216 MAV_1781 Mycobacterium avium 104 hypothetical protein YP_881005.1 1775525 D 243243 CDS YP_881006.1 118463184 4527707 1776070..1777101 1 NC_008595.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter sulfate-binding protein 1777101 4527707 MAV_1782 Mycobacterium avium 104 sulfate ABC transporter sulfate-binding protein YP_881006.1 1776070 D 243243 CDS YP_881007.1 118463091 4528914 1777098..1777970 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease 1777970 cysT 4528914 cysT Mycobacterium avium 104 sulfate ABC transporter permease YP_881007.1 1777098 D 243243 CDS YP_881008.1 118465860 4530654 1777967..1778785 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease 1778785 cysW 4530654 cysW Mycobacterium avium 104 sulfate ABC transporter permease YP_881008.1 1777967 D 243243 CDS YP_881009.1 118465142 4529174 1778800..1779888 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM TIGR00968; sulfate/thiosulfate import ATP-binding protein CysA 1779888 4529174 MAV_1785 Mycobacterium avium 104 sulfate/thiosulfate import ATP-binding protein CysA YP_881009.1 1778800 D 243243 CDS YP_881010.1 118464214 4526894 complement(1779935..1780678) 1 NC_008595.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 1780678 4526894 MAV_1786 Mycobacterium avium 104 phosphoadenosine phosphosulfate reductase YP_881010.1 1779935 R 243243 CDS YP_881011.1 118463702 4530589 complement(1780675..1782384) 1 NC_008595.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase [ferredoxin] 2 1782384 4530589 MAV_1787 Mycobacterium avium 104 sulfite reductase [ferredoxin] 2 YP_881011.1 1780675 R 243243 CDS YP_881012.1 118464092 4525853 1782409..1782612 1 NC_008595.1 hypothetical protein 1782612 4525853 MAV_1788 Mycobacterium avium 104 hypothetical protein YP_881012.1 1782409 D 243243 CDS YP_881013.1 118463403 4528030 1782682..1783854 1 NC_008595.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1783854 4528030 MAV_1789 Mycobacterium avium 104 coproporphyrinogen III oxidase YP_881013.1 1782682 D 243243 CDS YP_881014.1 118462832 4528646 complement(1783861..1785102) 1 NC_008595.1 identified by match to protein family HMM PF05982; hypothetical protein 1785102 4528646 MAV_1790 Mycobacterium avium 104 hypothetical protein YP_881014.1 1783861 R 243243 CDS YP_881015.1 118462450 4525623 complement(1785532..1786806) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1786806 4525623 MAV_1791 Mycobacterium avium 104 transposase, Mutator family protein YP_881015.1 1785532 R 243243 CDS YP_881016.1 118466860 4529812 1787016..1788368 1 NC_008595.1 catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; salicylate synthase MbtI 1788368 4529812 MAV_1792 Mycobacterium avium 104 salicylate synthase MbtI YP_881016.1 1787016 D 243243 CDS YP_881017.1 118466518 4527191 1788529..1789545 1 NC_008595.1 identified by match to protein family HMM PF03405; Fatty acid desaturase 1789545 4527191 MAV_1793 Mycobacterium avium 104 Fatty acid desaturase YP_881017.1 1788529 D 243243 CDS YP_881018.1 118465616 4527875 complement(1789878..1790744) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1790744 4527875 MAV_1794 Mycobacterium avium 104 MerR family transcriptional regulator YP_881018.1 1789878 R 243243 CDS YP_881019.1 118463728 4528078 complement(1790819..1792315) 1 NC_008595.1 identified by match to protein family HMM PF01266; flavin-binding monooxygenase 1792315 4528078 MAV_1795 Mycobacterium avium 104 flavin-binding monooxygenase YP_881019.1 1790819 R 243243 CDS YP_881020.1 118463990 4530349 complement(1792318..1793238) 1 NC_008595.1 hypothetical protein 1793238 4530349 MAV_1796 Mycobacterium avium 104 hypothetical protein YP_881020.1 1792318 R 243243 CDS YP_881021.1 118463845 4529944 complement(1793263..1794111) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 1794111 4529944 MAV_1797 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_881021.1 1793263 R 243243 CDS YP_881022.1 118464610 4526767 complement(1794113..1795030) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 1795030 4526767 MAV_1798 Mycobacterium avium 104 alpha/beta hydrolase YP_881022.1 1794113 R 243243 CDS YP_881023.1 118464666 4528263 1795163..1795279 1 NC_008595.1 hypothetical protein 1795279 4528263 MAV_1799 Mycobacterium avium 104 hypothetical protein YP_881023.1 1795163 D 243243 CDS YP_881024.1 118462734 4527805 complement(1795281..1795697) 1 NC_008595.1 identified by match to protein family HMM PF01878; hypothetical protein 1795697 4527805 MAV_1800 Mycobacterium avium 104 hypothetical protein YP_881024.1 1795281 R 243243 CDS YP_881025.1 118463333 4529203 complement(1795857..1796525) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1796525 4529203 MAV_1801 Mycobacterium avium 104 TetR family transcriptional regulator YP_881025.1 1795857 R 243243 CDS YP_881026.1 118463465 4525518 1796636..1797781 1 NC_008595.1 identified by match to protein family HMM PF00903; 2,3-dihydroxybiphenyl-1,2-dioxygenase 1797781 4525518 MAV_1802 Mycobacterium avium 104 2,3-dihydroxybiphenyl-1,2-dioxygenase YP_881026.1 1796636 D 243243 CDS YP_881027.1 118466125 4529758 1797778..1798719 1 NC_008595.1 identified by match to protein family HMM PF01557; 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1798719 4529758 MAV_1803 Mycobacterium avium 104 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_881027.1 1797778 D 243243 CDS YP_881028.1 118466916 4529461 1798825..1800252 1 NC_008595.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 1800252 mhpA 4529461 mhpA Mycobacterium avium 104 3-(3-hydroxyphenyl)propionate hydroxylase YP_881028.1 1798825 D 243243 CDS YP_881029.1 118464930 4528570 complement(1800291..1801565) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1801565 4528570 MAV_1805 Mycobacterium avium 104 transposase, Mutator family protein YP_881029.1 1800291 R 243243 CDS YP_881030.1 118466439 4527112 1801703..1802380 1 NC_008595.1 identified by match to protein family HMM PF01695; LprM protein 1802380 4527112 MAV_1806 Mycobacterium avium 104 LprM protein YP_881030.1 1801703 D 243243 CDS YP_881031.1 118466050 4528058 1802421..1803848 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 1803848 4528058 MAV_1807 Mycobacterium avium 104 virulence factor Mce YP_881031.1 1802421 D 243243 CDS YP_881032.1 118464388 4528277 complement(1805113..1805910) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 1805910 4528277 MAV_1809 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881032.1 1805113 R 243243 CDS YP_881033.1 118463073 4527572 complement(1805924..1806793) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1806793 4527572 MAV_1810 Mycobacterium avium 104 carveol dehydrogenase YP_881033.1 1805924 R 243243 CDS YP_881034.1 118467171 4530141 1806924..1807751 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1807751 4530141 MAV_1811 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881034.1 1806924 D 243243 CDS YP_881035.1 118467201 4528435 complement(1807816..1808595) 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-hydroxyacyl-CoA dehydrogenase type-2 1808595 4528435 MAV_1812 Mycobacterium avium 104 3-hydroxyacyl-CoA dehydrogenase type-2 YP_881035.1 1807816 R 243243 CDS YP_881036.1 118466649 4528087 complement(1808605..1809702) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1809702 4528087 MAV_1813 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881036.1 1808605 R 243243 CDS YP_881037.1 118465364 4529225 complement(1809699..1810847) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 1810847 4529225 MAV_1814 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881037.1 1809699 R 243243 CDS YP_881038.1 118464511 4525554 complement(1810860..1811729) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 1811729 4525554 MAV_1815 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881038.1 1810860 R 243243 CDS YP_881039.1 118463345 4529215 1811834..1813057 1 NC_008595.1 hypothetical protein 1813057 4529215 MAV_1816 Mycobacterium avium 104 hypothetical protein YP_881039.1 1811834 D 243243 CDS YP_881040.1 118462845 4526027 1813054..1814214 1 NC_008595.1 identified by match to protein family HMM PF02803; thiolase 1814214 4526027 MAV_1817 Mycobacterium avium 104 thiolase YP_881040.1 1813054 D 243243 CDS YP_881041.1 118466393 4526194 1814228..1815037 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 1815037 4526194 MAV_1818 Mycobacterium avium 104 enoyl-CoA hydratase YP_881041.1 1814228 D 243243 CDS YP_881042.1 118465499 4526795 1815066..1815461 1 NC_008595.1 identified by match to protein family HMM PF03061; esterase 1815461 4526795 MAV_1819 Mycobacterium avium 104 esterase YP_881042.1 1815066 D 243243 CDS YP_881043.1 118464491 4528865 complement(1815465..1816301) 1 NC_008595.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1816301 4528865 MAV_1820 Mycobacterium avium 104 hypothetical protein YP_881043.1 1815465 R 243243 CDS YP_881044.1 118463919 4528099 complement(1816298..1817038) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1817038 4528099 MAV_1821 Mycobacterium avium 104 GntR family transcriptional regulator YP_881044.1 1816298 R 243243 CDS YP_881045.1 118464119 4526290 complement(1817145..1818287) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; long-chain specific acyl-CoA dehydrogenase 1818287 4526290 MAV_1822 Mycobacterium avium 104 long-chain specific acyl-CoA dehydrogenase YP_881045.1 1817145 R 243243 CDS YP_881046.1 118463495 4529074 complement(1818297..1819295) 1 NC_008595.1 identified by match to protein family HMM PF00441; acyl-CoA dehydrogenase 1819295 4529074 MAV_1823 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881046.1 1818297 R 243243 CDS YP_881047.1 118462772 4527269 complement(1819292..1820248) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 1820248 4527269 MAV_1824 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881047.1 1819292 R 243243 CDS YP_881048.1 118466721 4530659 1820623..1822119 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1822119 4530659 MAV_1825 Mycobacterium avium 104 aldehyde dehydrogenase YP_881048.1 1820623 D 243243 CDS YP_881049.1 118462387 4525930 1822149..1823360 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 1823360 4525930 MAV_1826 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881049.1 1822149 D 243243 CDS YP_881050.1 118466943 4527778 1823660..1824304 1 NC_008595.1 hypothetical protein 1824304 4527778 MAV_1827 Mycobacterium avium 104 hypothetical protein YP_881050.1 1823660 D 243243 CDS YP_881051.1 118467096 4526396 1824522..1825166 1 NC_008595.1 hypothetical protein 1825166 4526396 MAV_1828 Mycobacterium avium 104 hypothetical protein YP_881051.1 1824522 D 243243 CDS YP_881052.1 118466537 4527005 1825208..1826020 1 NC_008595.1 identified by match to protein family HMM PF00106; retinol dehydrogenase 14 1826020 4527005 MAV_1829 Mycobacterium avium 104 retinol dehydrogenase 14 YP_881052.1 1825208 D 243243 CDS YP_881053.1 118464534 4530404 1826017..1827099 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 1827099 dapB 4530404 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_881053.1 1826017 D 243243 CDS YP_881054.1 118466731 4530669 1826931..1827539 1 NC_008595.1 hypothetical protein 1827539 4530669 MAV_1831 Mycobacterium avium 104 hypothetical protein YP_881054.1 1826931 D 243243 CDS YP_881055.1 118463960 4527206 1827587..1828339 1 NC_008595.1 identified by match to protein family HMM PF00106; 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase 1828339 4527206 MAV_1832 Mycobacterium avium 104 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase YP_881055.1 1827587 D 243243 CDS YP_881056.1 118463356 4529890 complement(1828400..1829311) 1 NC_008595.1 identified by match to protein family HMM PF00106; peroxisomal hydratase-dehydrogenase-epimerase (HDE) (multifunctionalbeta-oxidation protein) (MFP) 1829311 4529890 MAV_1833 Mycobacterium avium 104 peroxisomal hydratase-dehydrogenase-epimerase (HDE) (multifunctionalbeta-oxidation protein) (MFP) YP_881056.1 1828400 R 243243 CDS YP_881057.1 118462805 4529025 complement(1829321..1830511) 1 NC_008595.1 acetyl-CoA hydrolase/transferase 1830511 4529025 MAV_1834 Mycobacterium avium 104 acetyl-CoA hydrolase/transferase YP_881057.1 1829321 R 243243 CDS YP_881058.1 118466935 4527770 complement(1830508..1831653) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase protein 1831653 4527770 MAV_1835 Mycobacterium avium 104 acyl-CoA dehydrogenase protein YP_881058.1 1830508 R 243243 CDS YP_881059.1 118466936 4527771 complement(1831655..1831906) 1 NC_008595.1 hypothetical protein 1831906 4527771 MAV_1836 Mycobacterium avium 104 hypothetical protein YP_881059.1 1831655 R 243243 CDS YP_881060.1 118467152 4527583 complement(1831903..1833054) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1833054 4527583 MAV_1837 Mycobacterium avium 104 amidohydrolase YP_881060.1 1831903 R 243243 CDS YP_881061.1 118463775 4530126 complement(1833262..1834383) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase protein 1834383 4530126 MAV_1838 Mycobacterium avium 104 acyl-CoA dehydrogenase protein YP_881061.1 1833262 R 243243 CDS YP_881062.1 118464263 4528218 complement(1834380..1835873) 1 NC_008595.1 identified by match to protein family HMM PF00501; cyclohex-1-ene-1-carboxylate:CoA ligase 1835873 4528218 MAV_1839 Mycobacterium avium 104 cyclohex-1-ene-1-carboxylate:CoA ligase YP_881062.1 1834380 R 243243 CDS YP_881063.1 118466225 4528905 complement(1835870..1836721) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1836721 4528905 MAV_1840 Mycobacterium avium 104 alpha/beta hydrolase YP_881063.1 1835870 R 243243 CDS YP_881064.1 118466806 4529052 complement(1836725..1837945) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 1837945 4529052 MAV_1841 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_881064.1 1836725 R 243243 CDS YP_881065.1 118462846 4526028 complement(1837969..1839123) 1 NC_008595.1 lipid-transfer protein 1839123 4526028 MAV_1842 Mycobacterium avium 104 lipid-transfer protein YP_881065.1 1837969 R 243243 CDS YP_881066.1 118463225 4528799 1839244..1840758 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 1840758 4528799 MAV_1843 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881066.1 1839244 D 243243 CDS YP_881067.1 118463982 4530340 1840770..1841069 1 NC_008595.1 hypothetical protein 1841069 4530340 MAV_1844 Mycobacterium avium 104 hypothetical protein YP_881067.1 1840770 D 243243 CDS YP_881068.1 118464454 4527047 1841072..1841974 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1841974 4527047 MAV_1846 Mycobacterium avium 104 alpha/beta hydrolase YP_881068.1 1841072 D 243243 CDS YP_881069.1 118465820 4525923 1844550..1845938 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 1845938 4525923 MAV_1847 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_881069.1 1844550 D 243243 CDS YP_881070.1 118465224 4525594 1845991..1846974 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; dihydroflavonol-4-reductase 1846974 4525594 MAV_1849 Mycobacterium avium 104 dihydroflavonol-4-reductase YP_881070.1 1845991 D 243243 CDS YP_881071.1 118467126 4526153 complement(1846971..1847801) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1847801 4526153 MAV_1848 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881071.1 1846971 R 243243 CDS YP_881072.1 118466663 4526613 complement(1847828..1848472) 1 NC_008595.1 identified by match to protein family HMM PF05368; hypothetical protein 1848472 4526613 MAV_1850 Mycobacterium avium 104 hypothetical protein YP_881072.1 1847828 R 243243 CDS YP_881073.1 118467235 4529792 complement(1848494..1849726) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1849726 4529792 MAV_1851 Mycobacterium avium 104 amidohydrolase YP_881073.1 1848494 R 243243 CDS YP_881074.1 118466683 4530425 1849850..1850479 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1850479 4530425 MAV_1852 Mycobacterium avium 104 TetR family transcriptional regulator YP_881074.1 1849850 D 243243 CDS YP_881075.1 118462857 4526039 complement(1850582..1850827) 1 NC_008595.1 MFS transporter 1850827 4526039 MAV_1853 Mycobacterium avium 104 MFS transporter YP_881075.1 1850582 R 243243 CDS YP_881076.1 118462336 4525681 complement(1850866..1851156) 1 NC_008595.1 transposase 1851156 4525681 MAV_1854 Mycobacterium avium 104 transposase YP_881076.1 1850866 R 243243 CDS YP_881077.1 118464387 4528276 complement(1851272..1852546) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1852546 4528276 MAV_1855 Mycobacterium avium 104 transposase, Mutator family protein YP_881077.1 1851272 R 243243 CDS YP_881078.1 118464536 4530406 complement(1852540..1853325) 1 NC_008595.1 transposase 1853325 4530406 MAV_1856 Mycobacterium avium 104 transposase YP_881078.1 1852540 R 243243 CDS YP_881079.1 118465642 4526167 complement(1853614..1854720) 1 NC_008595.1 identified by match to protein family HMM PF00355; oxygenase KshA 1854720 4526167 MAV_1857 Mycobacterium avium 104 oxygenase KshA YP_881079.1 1853614 R 243243 CDS YP_881080.1 118466227 4526573 complement(1854851..1855483) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1855483 4526573 MAV_1858 Mycobacterium avium 104 TetR family transcriptional regulator YP_881080.1 1854851 R 243243 CDS YP_881081.1 118463008 4526301 1855609..1856607 1 NC_008595.1 identified by match to protein family HMM PF00355; iron-sulfur cluster-binding protein, Rieske family protein 1856607 4526301 MAV_1859 Mycobacterium avium 104 iron-sulfur cluster-binding protein, Rieske family protein YP_881081.1 1855609 D 243243 CDS YP_881082.1 118463803 4525885 1856651..1857391 1 NC_008595.1 hypothetical protein 1857391 4525885 MAV_1860 Mycobacterium avium 104 hypothetical protein YP_881082.1 1856651 D 243243 CDS YP_881083.1 118465762 4530455 complement(1858426..1858851) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 1858851 4530455 MAV_1862 Mycobacterium avium 104 hypothetical protein YP_881083.1 1858426 R 243243 CDS YP_881084.1 118466636 4526992 complement(1858853..1860040) 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; beta-ketoadipyl CoA thiolase 1860040 4526992 MAV_1863 Mycobacterium avium 104 beta-ketoadipyl CoA thiolase YP_881084.1 1858853 R 243243 CDS YP_881085.1 118463781 4530132 1860151..1860609 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC domain-containing protein 1860609 4530132 MAV_1864 Mycobacterium avium 104 MaoC domain-containing protein YP_881085.1 1860151 D 243243 CDS YP_881086.1 118464396 4530790 1860609..1861820 1 NC_008595.1 DitF protein 1861820 4530790 MAV_1865 Mycobacterium avium 104 DitF protein YP_881086.1 1860609 D 243243 CDS YP_881087.1 118462852 4526034 1861826..1863388 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 1863388 4526034 MAV_1867 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881087.1 1861826 D 243243 CDS YP_881088.1 118467247 4526082 complement(1863385..1863852) 1 NC_008595.1 hypothetical protein 1863852 4526082 MAV_1866 Mycobacterium avium 104 hypothetical protein YP_881088.1 1863385 R 243243 CDS YP_881089.1 118462871 4527099 1863901..1864281 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 1864281 4527099 MAV_1869 Mycobacterium avium 104 hypothetical protein YP_881089.1 1863901 D 243243 CDS YP_881090.1 118464482 4528856 complement(1865539..1865853) 1 NC_008595.1 hypothetical protein 1865853 4528856 MAV_1870 Mycobacterium avium 104 hypothetical protein YP_881090.1 1865539 R 243243 CDS YP_881091.1 118463737 4528145 1865955..1866392 1 NC_008595.1 amidohydrolase 1866392 4528145 MAV_1872 Mycobacterium avium 104 amidohydrolase YP_881091.1 1865955 D 243243 CDS YP_881092.1 118464347 4529149 complement(1866347..1867264) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1867264 4529149 MAV_1871 Mycobacterium avium 104 transposase YP_881092.1 1866347 R 243243 CDS YP_881093.1 118465137 4529168 complement(1867264..1867539) 1 NC_008595.1 transposase 1867539 4529168 MAV_1873 Mycobacterium avium 104 transposase YP_881093.1 1867264 R 243243 CDS YP_881094.1 118467269 4527071 1867689..1868483 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1868483 4527071 MAV_1874 Mycobacterium avium 104 amidohydrolase YP_881094.1 1867689 D 243243 CDS YP_881095.1 118466609 4526846 1868816..1869001 1 NC_008595.1 LppE protein 1869001 4526846 MAV_1875 Mycobacterium avium 104 LppE protein YP_881095.1 1868816 D 243243 CDS YP_881096.1 118466163 4528786 1869018..1869212 1 NC_008595.1 hypothetical protein 1869212 4528786 MAV_1876 Mycobacterium avium 104 hypothetical protein YP_881096.1 1869018 D 243243 CDS YP_881097.1 118465511 4528928 1869284..1871572 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1871572 4528928 MAV_1877 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881097.1 1869284 D 243243 CDS YP_881098.1 118465377 4529668 1871557..1872741 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 1872741 4529668 MAV_1878 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881098.1 1871557 D 243243 CDS YP_881099.1 118462775 4527272 complement(1872753..1873742) 1 NC_008595.1 identified by match to protein family HMM PF00441; acyl-CoA dehydrogenase 1873742 4527272 MAV_1879 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881099.1 1872753 R 243243 CDS YP_881100.1 118463549 4526816 1873831..1875345 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 1875345 4526816 MAV_1880 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881100.1 1873831 D 243243 CDS YP_881101.1 118462966 4526334 1875357..1876214 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1876214 4526334 MAV_1881 Mycobacterium avium 104 carveol dehydrogenase YP_881101.1 1875357 D 243243 CDS YP_881102.1 118462515 4528593 1876224..1877519 1 NC_008595.1 hypothetical protein 1877519 4528593 MAV_1882 Mycobacterium avium 104 hypothetical protein YP_881102.1 1876224 D 243243 CDS YP_881103.1 118465055 4527031 1877527..1878669 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1878669 4527031 MAV_1883 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881103.1 1877527 D 243243 CDS YP_881104.1 118467101 4526362 1878666..1879424 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA isomerase 1879424 4526362 MAV_1884 Mycobacterium avium 104 enoyl-CoA isomerase YP_881104.1 1878666 D 243243 CDS YP_881105.1 118463977 4530335 complement(1879467..1880180) 1 NC_008595.1 hypothetical protein 1880180 4530335 MAV_1885 Mycobacterium avium 104 hypothetical protein YP_881105.1 1879467 R 243243 CDS YP_881106.1 118463598 4527545 1880433..1880561 1 NC_008595.1 hypothetical protein 1880561 4527545 MAV_1886 Mycobacterium avium 104 hypothetical protein YP_881106.1 1880433 D 243243 CDS YP_881107.1 118466359 4530499 1880650..1880994 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 1880994 4530499 MAV_1887 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_881107.1 1880650 D 243243 CDS YP_881108.1 118466284 4529530 1881072..1881911 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1881911 4529530 MAV_1889 Mycobacterium avium 104 transposase YP_881108.1 1881072 D 243243 CDS YP_881109.1 118462950 4530235 complement(1881648..1882850) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 1882850 4530235 MAV_1888 Mycobacterium avium 104 hypothetical protein YP_881109.1 1881648 R 243243 CDS YP_881110.1 118462681 4530608 complement(1882903..1883499) 1 NC_008595.1 identified by match to protein family HMM PF01613; flavin reductase-like domain-containing protein 1883499 4530608 MAV_1890 Mycobacterium avium 104 flavin reductase-like domain-containing protein YP_881110.1 1882903 R 243243 CDS YP_881111.1 118463249 4525785 1883755..1884543 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 1884543 4525785 MAV_1891 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881111.1 1883755 D 243243 CDS YP_881112.1 118465945 4527941 complement(1884544..1885740) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 1885740 4527941 MAV_1892 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881112.1 1884544 R 243243 CDS YP_881113.1 118463934 4528114 1886042..1886950 1 NC_008595.1 identified by match to protein family HMM PF02515; Mcr protein 1886950 4528114 MAV_1893 Mycobacterium avium 104 Mcr protein YP_881113.1 1886042 D 243243 CDS YP_881114.1 118466857 4529809 1887129..1887719 1 NC_008595.1 hypothetical protein 1887719 4529809 MAV_1894 Mycobacterium avium 104 hypothetical protein YP_881114.1 1887129 D 243243 CDS YP_881115.1 118464854 4527970 complement(1887728..1888957) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 1888957 4527970 MAV_1895 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881115.1 1887728 R 243243 CDS YP_881116.1 118462443 4525616 complement(1889054..1890226) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1890226 4525616 MAV_1896 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881116.1 1889054 R 243243 CDS YP_881117.1 118463698 4530585 complement(1890252..1891757) 1 NC_008595.1 identified by match to protein family HMM PF00171; betaine-aldehyde dehydrogenase 1891757 4530585 MAV_1897 Mycobacterium avium 104 betaine-aldehyde dehydrogenase YP_881117.1 1890252 R 243243 CDS YP_881118.1 118465866 4527508 complement(1891767..1892549) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1892549 4527508 MAV_1898 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881118.1 1891767 R 243243 CDS YP_881119.1 118465191 4530388 complement(1892546..1894078) 1 NC_008595.1 identified by match to protein family HMM PF00501; feruloyl-CoA synthetase 1894078 4530388 MAV_1899 Mycobacterium avium 104 feruloyl-CoA synthetase YP_881119.1 1892546 R 243243 CDS YP_881120.1 118467322 4526960 complement(1894094..1894618) 1 NC_008595.1 identified by match to protein family HMM PF00866; small subunit of dioxygenase in aniline dioxygenase 1894618 4526960 MAV_1900 Mycobacterium avium 104 small subunit of dioxygenase in aniline dioxygenase YP_881120.1 1894094 R 243243 CDS YP_881121.1 118466922 4529468 complement(1894615..1895910) 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM PF00848; dioxygenase large subunit 1895910 4529468 MAV_1901 Mycobacterium avium 104 dioxygenase large subunit YP_881121.1 1894615 R 243243 CDS YP_881122.1 118463439 4528319 complement(1895907..1896353) 1 NC_008595.1 hypothetical protein 1896353 4528319 MAV_1902 Mycobacterium avium 104 hypothetical protein YP_881122.1 1895907 R 243243 CDS YP_881123.1 118462875 4527103 complement(1896362..1897516) 1 NC_008595.1 thiolase 1897516 4527103 MAV_1903 Mycobacterium avium 104 thiolase YP_881123.1 1896362 R 243243 CDS YP_881124.1 118462496 4530692 complement(1897513..1897758) 1 NC_008595.1 hypothetical protein 1897758 4530692 MAV_1904 Mycobacterium avium 104 hypothetical protein YP_881124.1 1897513 R 243243 CDS YP_881125.1 118466545 4527013 1897955..1898884 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase 1898884 4527013 MAV_1905 Mycobacterium avium 104 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase YP_881125.1 1897955 D 243243 CDS YP_881126.1 118463705 4530592 1898889..1899731 1 NC_008595.1 identified by match to protein family HMM PF01689; match to protein family HMM TIGR02312; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1899731 hpaH 4530592 hpaH Mycobacterium avium 104 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_881126.1 1898889 D 243243 CDS YP_881127.1 118466295 4529542 1899779..1900498 1 NC_008595.1 identified by match to protein family HMM PF03328; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 1900498 4529542 MAV_1907 Mycobacterium avium 104 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_881127.1 1899779 D 243243 CDS YP_881128.1 118463618 4527322 1900495..1901613 1 NC_008595.1 identified by match to protein family HMM PF00296; FMN-dependent monooxygenase 1901613 4527322 MAV_1908 Mycobacterium avium 104 FMN-dependent monooxygenase YP_881128.1 1900495 D 243243 CDS YP_881129.1 118464162 4526472 1901730..1902902 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase domain-containing protein 1902902 4526472 MAV_1909 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_881129.1 1901730 D 243243 CDS YP_881130.1 118462533 4527676 1902922..1903944 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 1903944 4527676 MAV_1910 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881130.1 1902922 D 243243 CDS YP_881131.1 118463076 4527575 1903941..1905101 1 NC_008595.1 thiolase 1905101 4527575 MAV_1911 Mycobacterium avium 104 thiolase YP_881131.1 1903941 D 243243 CDS YP_881132.1 118466980 4530379 1905102..1906601 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 1906601 4530379 MAV_1912 Mycobacterium avium 104 acyl-CoA synthase YP_881132.1 1905102 D 243243 CDS YP_881133.1 118462569 4528628 1906634..1907428 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1907428 4528628 MAV_1913 Mycobacterium avium 104 carveol dehydrogenase YP_881133.1 1906634 D 243243 CDS YP_881134.1 118465899 4527933 complement(1907438..1908073) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 1908073 4527933 MAV_1914 Mycobacterium avium 104 thioesterase YP_881134.1 1907438 R 243243 CDS YP_881135.1 118466606 4529372 1908201..1910657 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 1910657 4529372 MAV_1915 Mycobacterium avium 104 caib/baif family protein YP_881135.1 1908201 D 243243 CDS YP_881136.1 118466450 4527123 complement(1910662..1911273) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1911273 4527123 MAV_1916 Mycobacterium avium 104 TetR family transcriptional regulator YP_881136.1 1910662 R 243243 CDS YP_881137.1 118467173 4530143 1911491..1912621 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1912621 4530143 MAV_1917 Mycobacterium avium 104 amidohydrolase YP_881137.1 1911491 D 243243 CDS YP_881138.1 118465174 4528664 1912626..1913825 1 NC_008595.1 thiolase 1913825 4528664 MAV_1918 Mycobacterium avium 104 thiolase YP_881138.1 1912626 D 243243 CDS YP_881139.1 118465721 4527456 1913822..1914271 1 NC_008595.1 identified by match to protein family HMM PF01796; acyl dehydratase 1914271 4527456 MAV_1919 Mycobacterium avium 104 acyl dehydratase YP_881139.1 1913822 D 243243 CDS YP_881140.1 118463719 4528069 1914278..1914487 1 NC_008595.1 hypothetical protein 1914487 4528069 MAV_1920 Mycobacterium avium 104 hypothetical protein YP_881140.1 1914278 D 243243 CDS YP_881141.1 118464310 4526640 1914507..1915322 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 1915322 4526640 MAV_1921 Mycobacterium avium 104 carveol dehydrogenase YP_881141.1 1914507 D 243243 CDS YP_881142.1 118462293 4525638 1915572..1916807 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 1916807 4525638 MAV_1922 Mycobacterium avium 104 aldehyde dehydrogenase YP_881142.1 1915572 D 243243 CDS YP_881143.1 118467066 4526444 1916987..1917277 1 NC_008595.1 hypothetical protein 1917277 4526444 MAV_1923 Mycobacterium avium 104 hypothetical protein YP_881143.1 1916987 D 243243 CDS YP_881144.1 118464070 4528383 1917320..1917577 1 NC_008595.1 hypothetical protein 1917577 4528383 MAV_1924 Mycobacterium avium 104 hypothetical protein YP_881144.1 1917320 D 243243 CDS YP_881145.1 118467058 4526436 1917570..1917965 1 NC_008595.1 hypothetical protein 1917965 4526436 MAV_1926 Mycobacterium avium 104 hypothetical protein YP_881145.1 1917570 D 243243 CDS YP_881146.1 118465367 4529228 complement(1917942..1919246) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1919246 4529228 MAV_1925 Mycobacterium avium 104 transposase, Mutator family protein YP_881146.1 1917942 R 243243 CDS YP_881147.1 118463914 4525845 1919399..1920034 1 NC_008595.1 hypothetical protein 1920034 4525845 MAV_1927 Mycobacterium avium 104 hypothetical protein YP_881147.1 1919399 D 243243 CDS YP_881148.1 118465258 4528477 1920043..1920873 1 NC_008595.1 identified by match to protein family HMM PF03446; match to protein family HMM PF03807; 6-phosphogluconate dehydrogenase 1920873 4528477 MAV_1928 Mycobacterium avium 104 6-phosphogluconate dehydrogenase YP_881148.1 1920043 D 243243 CDS YP_881149.1 118465772 4526907 complement(1920884..1921969) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase 1921969 4526907 MAV_1929 Mycobacterium avium 104 phosphotransferase YP_881149.1 1920884 R 243243 CDS YP_881150.1 118465206 4529843 1922014..1923075 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 1923075 4529843 MAV_1930 Mycobacterium avium 104 hypothetical protein YP_881150.1 1922014 D 243243 CDS YP_881151.1 118467262 4526097 complement(1923128..1923763) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1923763 4526097 MAV_1931 Mycobacterium avium 104 TetR family transcriptional regulator YP_881151.1 1923128 R 243243 CDS YP_881152.1 118466665 4526615 1923894..1925309 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 1925309 4526615 MAV_1932 Mycobacterium avium 104 amidohydrolase YP_881152.1 1923894 D 243243 CDS YP_881153.1 118462354 4527981 1926155..1926667 1 NC_008595.1 identified by match to protein family HMM PF00510; cytochrome C oxidase, subunit III family protein 1926667 4527981 MAV_1934 Mycobacterium avium 104 cytochrome C oxidase, subunit III family protein YP_881153.1 1926155 D 243243 CDS YP_881154.1 118465198 4530395 1926724..1926945 1 NC_008595.1 hypothetical protein 1926945 4530395 MAV_1935 Mycobacterium avium 104 hypothetical protein YP_881154.1 1926724 D 243243 CDS YP_881155.1 118463809 4526064 complement(1926949..1927530) 1 NC_008595.1 hypothetical protein 1927530 4526064 MAV_1936 Mycobacterium avium 104 hypothetical protein YP_881155.1 1926949 R 243243 CDS YP_881156.1 118462791 4525759 complement(1927534..1928457) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1928457 4525759 MAV_1937 Mycobacterium avium 104 short chain dehydrogenase YP_881156.1 1927534 R 243243 CDS YP_881157.1 118463335 4529205 complement(1928454..1928675) 1 NC_008595.1 hypothetical protein 1928675 4529205 MAV_1938 Mycobacterium avium 104 hypothetical protein YP_881157.1 1928454 R 243243 CDS YP_881158.1 118466820 4527385 complement(1928885..1929670) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 1929670 4527385 MAV_1939 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881158.1 1928885 R 243243 CDS YP_881159.1 118464835 4529740 complement(1929682..1930956) 1 NC_008595.1 identified by match to protein family HMM PF00067; NikQ protein 1930956 4529740 MAV_1940 Mycobacterium avium 104 NikQ protein YP_881159.1 1929682 R 243243 CDS YP_881160.1 118465111 4530463 1931111..1932193 1 NC_008595.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD-binding Rossmann fold protein 1932193 4530463 MAV_1941 Mycobacterium avium 104 oxidoreductase, NAD-binding Rossmann fold protein YP_881160.1 1931111 D 243243 CDS YP_881161.1 118465679 4525738 1932190..1932696 1 NC_008595.1 hypothetical protein 1932696 4525738 MAV_1942 Mycobacterium avium 104 hypothetical protein YP_881161.1 1932190 D 243243 CDS YP_881162.1 118463926 4528106 complement(1932859..1933992) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase B 1933992 4528106 MAV_1943 Mycobacterium avium 104 alcohol dehydrogenase B YP_881162.1 1932859 R 243243 CDS YP_881163.1 118464495 4525538 complement(1934010..1935464) 1 NC_008595.1 identified by match to protein family HMM PF00171; betaine-aldehyde dehydrogenase 1935464 4525538 MAV_1944 Mycobacterium avium 104 betaine-aldehyde dehydrogenase YP_881163.1 1934010 R 243243 CDS YP_881164.1 118466533 4527001 1935552..1935989 1 NC_008595.1 hypothetical protein 1935989 4527001 MAV_1945 Mycobacterium avium 104 hypothetical protein YP_881164.1 1935552 D 243243 CDS YP_881165.1 118466184 4526215 1936058..1936441 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC family protein 1936441 4526215 MAV_1946 Mycobacterium avium 104 MaoC family protein YP_881165.1 1936058 D 243243 CDS YP_881166.1 118464833 4529738 1936454..1937794 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 1937794 4529738 MAV_1948 Mycobacterium avium 104 transcriptional regulator YP_881166.1 1936454 D 243243 CDS YP_881167.1 118467006 4529476 complement(1937763..1938656) 1 NC_008595.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 1938656 mhpB 4529476 mhpB Mycobacterium avium 104 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_881167.1 1937763 R 243243 CDS YP_881168.1 118466306 4528348 complement(1938664..1938858) 1 NC_008595.1 hypothetical protein 1938858 4528348 MAV_1949 Mycobacterium avium 104 hypothetical protein YP_881168.1 1938664 R 243243 CDS YP_881169.1 118465871 4527513 complement(1938855..1940048) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 126 1940048 4527513 MAV_1950 Mycobacterium avium 104 cytochrome P450 126 YP_881169.1 1938855 R 243243 CDS YP_881170.1 118463082 4527581 1940434..1941366 1 NC_008595.1 postpolyketide modification protein 1941366 4527581 MAV_1951 Mycobacterium avium 104 postpolyketide modification protein YP_881170.1 1940434 D 243243 CDS YP_881171.1 118464508 4525551 complement(1941376..1941906) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 1941906 4525551 MAV_1952 Mycobacterium avium 104 transcriptional regulator YP_881171.1 1941376 R 243243 CDS YP_881172.1 118466761 4530756 1942146..1943306 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 1943306 4530756 MAV_1953 Mycobacterium avium 104 cytochrome P450 YP_881172.1 1942146 D 243243 CDS YP_881173.1 118462365 4527993 complement(1943322..1944242) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 1944242 4527993 MAV_1954 Mycobacterium avium 104 hypothetical protein YP_881173.1 1943322 R 243243 CDS YP_881174.1 118466599 4529365 1944417..1946024 1 NC_008595.1 identified by match to protein family HMM PF00391; PEP-utilizing protein 1946024 4529365 MAV_1955 Mycobacterium avium 104 PEP-utilizing protein YP_881174.1 1944417 D 243243 CDS YP_881175.1 118467312 4530305 1946031..1947041 1 NC_008595.1 hypothetical protein 1947041 4530305 MAV_1956 Mycobacterium avium 104 hypothetical protein YP_881175.1 1946031 D 243243 CDS YP_881176.1 118465150 4529240 1947073..1948683 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 1948683 4529240 MAV_1957 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881176.1 1947073 D 243243 CDS YP_881177.1 118465879 4527521 1948670..1949494 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 1949494 4527521 MAV_1958 Mycobacterium avium 104 short chain dehydrogenase YP_881177.1 1948670 D 243243 CDS YP_881178.1 118462876 4527104 complement(1949501..1950106) 1 NC_008595.1 hypothetical protein 1950106 4527104 MAV_1959 Mycobacterium avium 104 hypothetical protein YP_881178.1 1949501 R 243243 CDS YP_881179.1 118463033 4528874 complement(1950103..1951722) 1 NC_008595.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1951722 4528874 MAV_1960 Mycobacterium avium 104 pyruvate phosphate dikinase YP_881179.1 1950103 R 243243 CDS YP_881180.1 118462990 4530620 1951887..1952249 1 NC_008595.1 hypothetical protein 1952249 4530620 MAV_1961 Mycobacterium avium 104 hypothetical protein YP_881180.1 1951887 D 243243 CDS YP_881181.1 118462274 4529279 1952251..1952859 1 NC_008595.1 identified by match to protein family HMM PF00881; NADPH nitroreductase 1952859 4529279 MAV_1962 Mycobacterium avium 104 NADPH nitroreductase YP_881181.1 1952251 D 243243 CDS YP_881182.1 118462745 4527816 1952891..1955041 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 1955041 4527816 MAV_1963 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881182.1 1952891 D 243243 CDS YP_881183.1 118463953 4526605 1955124..1956191 1 NC_008595.1 lipid-transfer protein 1956191 4526605 MAV_1964 Mycobacterium avium 104 lipid-transfer protein YP_881183.1 1955124 D 243243 CDS YP_881184.1 118465775 4526910 1956188..1956607 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 1956607 4526910 MAV_1966 Mycobacterium avium 104 hypothetical protein YP_881184.1 1956188 D 243243 CDS YP_881185.1 118465073 4525890 complement(1956604..1957632) 1 NC_008595.1 hypothetical protein 1957632 4525890 MAV_1965 Mycobacterium avium 104 hypothetical protein YP_881185.1 1956604 R 243243 CDS YP_881186.1 118466896 4528410 complement(1957801..1958157) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 1958157 4528410 MAV_1967 Mycobacterium avium 104 hypothetical protein YP_881186.1 1957801 R 243243 CDS YP_881187.1 118463053 4528332 complement(1958253..1959074) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; retinol dehydrogenase 12 1959074 4528332 MAV_1968 Mycobacterium avium 104 retinol dehydrogenase 12 YP_881187.1 1958253 R 243243 CDS YP_881188.1 118462309 4529627 1959470..1959916 1 NC_008595.1 hypothetical protein 1959916 4529627 MAV_1969 Mycobacterium avium 104 hypothetical protein YP_881188.1 1959470 D 243243 CDS YP_881189.1 118462375 4529188 1959913..1960620 1 NC_008595.1 hypothetical protein 1960620 4529188 MAV_1970 Mycobacterium avium 104 hypothetical protein YP_881189.1 1959913 D 243243 CDS YP_881190.1 118464235 4528608 1960844..1961917 1 NC_008595.1 hypothetical protein 1961917 4528608 MAV_1971 Mycobacterium avium 104 hypothetical protein YP_881190.1 1960844 D 243243 CDS YP_881191.1 118465958 4527954 complement(1962064..1963470) 1 NC_008595.1 identified by match to protein family HMM PF01609; transposase 1963470 4527954 MAV_1972 Mycobacterium avium 104 transposase YP_881191.1 1962064 R 243243 CDS YP_881192.1 118464730 4529417 complement(1963649..1964140) 1 NC_008595.1 hypothetical protein 1964140 4529417 MAV_1973 Mycobacterium avium 104 hypothetical protein YP_881192.1 1963649 R 243243 CDS YP_881193.1 118465445 4527314 complement(1964419..1965693) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1965693 4527314 MAV_1974 Mycobacterium avium 104 transposase, Mutator family protein YP_881193.1 1964419 R 243243 CDS YP_881194.1 118462507 4528585 complement(1965746..1965892) 1 NC_008595.1 hypothetical protein 1965892 4528585 MAV_1975 Mycobacterium avium 104 hypothetical protein YP_881194.1 1965746 R 243243 CDS YP_881195.1 118463327 4529568 1965891..1966742 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1966742 4529568 MAV_1976 Mycobacterium avium 104 short chain dehydrogenase YP_881195.1 1965891 D 243243 CDS YP_881196.1 118462789 4525757 1966739..1967332 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1967332 4525757 MAV_1977 Mycobacterium avium 104 TetR family transcriptional regulator YP_881196.1 1966739 D 243243 CDS YP_881197.1 118463054 4528333 complement(1967487..1967651) 1 NC_008595.1 hypothetical protein 1967651 4528333 MAV_1978 Mycobacterium avium 104 hypothetical protein YP_881197.1 1967487 R 243243 CDS YP_881198.1 118464573 4530277 complement(1967946..1968632) 1 NC_008595.1 identified by match to protein family HMM PF01965; ThiJ/PfpI family protein 1968632 4530277 MAV_1979 Mycobacterium avium 104 ThiJ/PfpI family protein YP_881198.1 1967946 R 243243 CDS YP_881199.1 118463662 4525954 complement(1968781..1968900) 1 NC_008595.1 hypothetical protein 1968900 4525954 MAV_1980 Mycobacterium avium 104 hypothetical protein YP_881199.1 1968781 R 243243 CDS YP_881200.1 118464039 4529011 1969117..1969299 1 NC_008595.1 topology modulation protein 1969299 4529011 MAV_1981 Mycobacterium avium 104 topology modulation protein YP_881200.1 1969117 D 243243 CDS YP_881201.1 118467088 4526388 1969352..1969465 1 NC_008595.1 hypothetical protein 1969465 4526388 MAV_1982 Mycobacterium avium 104 hypothetical protein YP_881201.1 1969352 D 243243 CDS YP_881202.1 118463929 4528109 complement(1969486..1969578) 1 NC_008595.1 hypothetical protein 1969578 4528109 MAV_1983 Mycobacterium avium 104 hypothetical protein YP_881202.1 1969486 R 243243 CDS YP_881203.1 118463685 4528532 complement(1969593..1970060) 1 NC_008595.1 identified by match to protein family HMM PF01272; transcription elongation factor GreA 1970060 4528532 MAV_1984 Mycobacterium avium 104 transcription elongation factor GreA YP_881203.1 1969593 R 243243 CDS YP_881204.1 118465685 4525744 complement(1970057..1970590) 1 NC_008595.1 transcription elongation factor GreA 1970590 4525744 MAV_1985 Mycobacterium avium 104 transcription elongation factor GreA YP_881204.1 1970057 R 243243 CDS YP_881205.1 118466849 4526958 complement(1970944..1971576) 1 NC_008595.1 transmembrane protein 1971576 4526958 MAV_1986 Mycobacterium avium 104 transmembrane protein YP_881205.1 1970944 R 243243 CDS YP_881206.1 118466562 4529111 complement(1971729..1973249) 1 NC_008595.1 DNA-binding protein 1973249 4529111 MAV_1987 Mycobacterium avium 104 DNA-binding protein YP_881206.1 1971729 R 243243 CDS YP_881207.1 118465252 4528470 1973459..1973584 1 NC_008595.1 18 kDa antigen 2 1973584 4528470 MAV_1988 Mycobacterium avium 104 18 kDa antigen 2 YP_881207.1 1973459 D 243243 CDS YP_881208.1 118465990 4526132 1973633..1974907 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 1974907 4526132 MAV_1989 Mycobacterium avium 104 transposase, Mutator family protein YP_881208.1 1973633 D 243243 CDS YP_881209.1 118462377 4529190 1974987..1975316 1 NC_008595.1 identified by match to protein family HMM PF00011; 18 kDa antigen 2 1975316 4529190 MAV_1990 Mycobacterium avium 104 18 kDa antigen 2 YP_881209.1 1974987 D 243243 CDS YP_881210.1 118463261 4528126 1975371..1975706 1 NC_008595.1 hypothetical protein 1975706 4528126 MAV_1991 Mycobacterium avium 104 hypothetical protein YP_881210.1 1975371 D 243243 CDS YP_881211.1 118466964 4530363 1975906..1976097 1 NC_008595.1 hypothetical protein 1976097 4530363 MAV_1992 Mycobacterium avium 104 hypothetical protein YP_881211.1 1975906 D 243243 CDS YP_881212.1 118464438 4525969 1976294..1976668 1 NC_008595.1 identified by match to protein family HMM PF00376; HspR protein 1976668 4525969 MAV_1993 Mycobacterium avium 104 HspR protein YP_881212.1 1976294 D 243243 CDS YP_881213.1 118463674 4528519 1976688..1976798 1 NC_008595.1 hypothetical protein 1976798 4528519 MAV_1994 Mycobacterium avium 104 hypothetical protein YP_881213.1 1976688 D 243243 CDS YP_881214.1 118465235 4525606 1976948..1978027 1 NC_008595.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1978027 4525606 MAV_1995 Mycobacterium avium 104 diguanylate cyclase YP_881214.1 1976948 D 243243 CDS YP_881215.1 118464563 4530782 1978417..1978575 1 NC_008595.1 hypothetical protein 1978575 4530782 MAV_1996 Mycobacterium avium 104 hypothetical protein YP_881215.1 1978417 D 243243 CDS YP_881216.1 118466369 4529931 complement(1978609..1978971) 1 NC_008595.1 hypothetical protein 1978971 4529931 MAV_1997 Mycobacterium avium 104 hypothetical protein YP_881216.1 1978609 R 243243 CDS YP_881217.1 118466030 4529917 complement(1978968..1980299) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1980299 4529917 MAV_1998 Mycobacterium avium 104 PPE family protein YP_881217.1 1978968 R 243243 CDS YP_881218.1 118464236 4528609 complement(1980548..1980850) 1 NC_008595.1 hypothetical protein 1980850 4528609 MAV_1999 Mycobacterium avium 104 hypothetical protein YP_881218.1 1980548 R 243243 CDS YP_881219.1 118464861 4530697 complement(1981053..1982309) 1 NC_008595.1 hypothetical protein 1982309 4530697 MAV_2000 Mycobacterium avium 104 hypothetical protein YP_881219.1 1981053 R 243243 CDS YP_881220.1 118467296 4527254 complement(1982309..1982467) 1 NC_008595.1 hypothetical protein 1982467 4527254 MAV_2001 Mycobacterium avium 104 hypothetical protein YP_881220.1 1982309 R 243243 CDS YP_881221.1 118466528 4527201 complement(1982515..1983552) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 1983552 4527201 MAV_2002 Mycobacterium avium 104 transposase YP_881221.1 1982515 R 243243 CDS YP_881222.1 118465830 4525502 complement(1983571..1984749) 1 NC_008595.1 hypothetical protein 1984749 4525502 MAV_2003 Mycobacterium avium 104 hypothetical protein YP_881222.1 1983571 R 243243 CDS YP_881223.1 118465128 4529159 complement(1984749..1986395) 1 NC_008595.1 identified by match to protein family HMM PF01061; ABC transporter 1986395 4529159 MAV_2004 Mycobacterium avium 104 ABC transporter YP_881223.1 1984749 R 243243 CDS YP_881224.1 118467292 4527250 complement(1986429..1987820) 1 NC_008595.1 identified by match to protein family HMM PF00668; PapA2 protein 1987820 4527250 MAV_2005 Mycobacterium avium 104 PapA2 protein YP_881224.1 1986429 R 243243 CDS YP_881225.1 118466613 4526850 1988873..1990213 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 1990213 4526850 MAV_2006 Mycobacterium avium 104 PPE family protein YP_881225.1 1988873 D 243243 CDS YP_881226.1 118462941 4530226 1990630..1991691 1 NC_008595.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1991691 4530226 MAV_2007 Mycobacterium avium 104 phospho-2-dehydro-3-deoxyheptonate aldolase YP_881226.1 1990630 D 243243 CDS YP_881227.1 118462251 4526937 complement(1991786..1993441) 1 NC_008595.1 identified by match to protein family HMM PF00501; 2,3-dihydroxybenzoate-AMP ligase 1993441 4526937 MAV_2008 Mycobacterium avium 104 2,3-dihydroxybenzoate-AMP ligase YP_881227.1 1991786 R 243243 CDS YP_881228.1 118464419 4530240 1993551..1997045 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; MbtB protein 1997045 4530240 MAV_2009 Mycobacterium avium 104 MbtB protein YP_881228.1 1993551 D 243243 CDS YP_881229.1 118463704 4530591 1997156..1997818 1 NC_008595.1 identified by match to protein family HMM PF00975; phenyloxazoline synthase mbtb 1997818 4530591 MAV_2010 Mycobacterium avium 104 phenyloxazoline synthase mbtb YP_881229.1 1997156 D 243243 CDS YP_881230.1 118467200 4528434 1997815..1999143 1 NC_008595.1 identified by match to protein family HMM PF00109; match to protein family HMM PF02801; erythronolide synthase, modules 1 and 2 1999143 4528434 MAV_2011 Mycobacterium avium 104 erythronolide synthase, modules 1 and 2 YP_881230.1 1997815 D 243243 CDS YP_881231.1 118465281 4529316 1999140..2002181 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; MbtD protein 2002181 4529316 MAV_2012 Mycobacterium avium 104 MbtD protein YP_881231.1 1999140 D 243243 CDS YP_881232.1 118462221 4525558 2002183..2008755 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; linear gramicidin synthetase subunit D 2008755 4525558 MAV_2013 Mycobacterium avium 104 linear gramicidin synthetase subunit D YP_881232.1 2002183 D 243243 CDS YP_881233.1 118462908 4528171 2008752..2013194 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; sulfotransferase 2013194 4528171 MAV_2014 Mycobacterium avium 104 sulfotransferase YP_881233.1 2008752 D 243243 CDS YP_881234.1 118463821 4526077 2013191..2014477 1 NC_008595.1 MbtG protein 2014477 4526077 MAV_2015 Mycobacterium avium 104 MbtG protein YP_881234.1 2013191 D 243243 CDS YP_881235.1 118464383 4528272 2014458..2014673 1 NC_008595.1 identified by match to protein family HMM PF03621; hypothetical protein 2014673 4528272 MAV_2016 Mycobacterium avium 104 hypothetical protein YP_881235.1 2014458 D 243243 CDS YP_881236.1 118465220 4529857 2014849..2015385 1 NC_008595.1 low molecular weight antigen MTB12 2015385 4529857 MAV_2017 Mycobacterium avium 104 low molecular weight antigen MTB12 YP_881236.1 2014849 D 243243 CDS YP_881237.1 118465777 4526912 2015679..2016197 1 NC_008595.1 low molecular weight antigen MTB12 2016197 4526912 MAV_2019 Mycobacterium avium 104 low molecular weight antigen MTB12 YP_881237.1 2015679 D 243243 CDS YP_881238.1 118465340 4526653 complement(2016191..2017081) 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase ECF-subfamily protein sigma factor 2017081 4526653 MAV_2018 Mycobacterium avium 104 RNA polymerase ECF-subfamily protein sigma factor YP_881238.1 2016191 R 243243 CDS YP_881239.1 118465766 4530459 complement(2017078..2017674) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 2017674 pcaC 4530459 pcaC Mycobacterium avium 104 hypothetical protein YP_881239.1 2017078 R 243243 CDS YP_881240.1 118464359 4530502 complement(2017756..2018070) 1 NC_008595.1 hypothetical protein 2018070 4530502 MAV_2021 Mycobacterium avium 104 hypothetical protein YP_881240.1 2017756 R 243243 CDS YP_881241.1 118463562 4530717 2018286..2019317 1 NC_008595.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 2019317 hrcA 4530717 hrcA Mycobacterium avium 104 heat-inducible transcription repressor YP_881241.1 2018286 D 243243 CDS YP_881242.1 118462239 4526924 2019374..2020519 1 NC_008595.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2020519 dnaJ 4526924 dnaJ Mycobacterium avium 104 chaperone protein DnaJ YP_881242.1 2019374 D 243243 CDS YP_881243.1 118466945 4530257 2020543..2021304 1 NC_008595.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2021304 4530257 MAV_2024 Mycobacterium avium 104 16S ribosomal RNA methyltransferase RsmE YP_881243.1 2020543 D 243243 CDS YP_881244.1 118464015 4528811 2021465..2022523 1 NC_008595.1 identified by match to protein family HMM PF00013; match to protein family HMM PF02562; PhoH family protein 2022523 4528811 MAV_2025 Mycobacterium avium 104 PhoH family protein YP_881244.1 2021465 D 243243 CDS YP_881245.1 118462943 4530228 2022546..2023079 1 NC_008595.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; metalloprotease 2023079 4530228 MAV_2026 Mycobacterium avium 104 metalloprotease YP_881245.1 2022546 D 243243 CDS YP_881246.1 118466055 4530025 2023079..2024356 1 NC_008595.1 hypothetical protein 2024356 4530025 MAV_2027 Mycobacterium avium 104 hypothetical protein YP_881246.1 2023079 D 243243 CDS YP_881247.1 118465297 4529333 2024353..2025663 1 NC_008595.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain-containing protein 2025663 4529333 MAV_2028 Mycobacterium avium 104 CBS domain-containing protein YP_881247.1 2024353 D 243243 CDS YP_881248.1 118467125 4526152 2025656..2026555 1 NC_008595.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2026555 era 4526152 era Mycobacterium avium 104 GTP-binding protein Era YP_881248.1 2025656 D 243243 CDS YP_881249.1 118462378 4529191 2026560..2026697 1 NC_008595.1 hypothetical protein 2026697 4529191 MAV_2030 Mycobacterium avium 104 hypothetical protein YP_881249.1 2026560 D 243243 CDS YP_881250.1 118466398 4526240 complement(2026702..2028159) 1 NC_008595.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711; Orn/Lys/Arg decarboxylase 2028159 4526240 MAV_2031 Mycobacterium avium 104 Orn/Lys/Arg decarboxylase YP_881250.1 2026702 R 243243 CDS YP_881251.1 118466782 4529340 complement(2028234..2029613) 1 NC_008595.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 2029613 4529340 MAV_2032 Mycobacterium avium 104 amidase YP_881251.1 2028234 R 243243 CDS YP_881252.1 118462249 4526935 2029834..2030604 1 NC_008595.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2030604 recO 4526935 recO Mycobacterium avium 104 DNA repair protein RecO YP_881252.1 2029834 D 243243 CDS YP_881253.1 118462927 4526018 2030597..2031487 1 NC_008595.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 2031487 uppS 4526018 uppS Mycobacterium avium 104 undecaprenyl pyrophosphate synthase YP_881253.1 2030597 D 243243 CDS YP_881254.1 118464787 4526711 2031487..2031915 1 NC_008595.1 hypothetical protein 2031915 4526711 MAV_2035 Mycobacterium avium 104 hypothetical protein YP_881254.1 2031487 D 243243 CDS YP_881255.1 118463823 4526079 complement(2031994..2032401) 1 NC_008595.1 identified by match to protein family HMM PF01475; FurB protein 2032401 4526079 MAV_2036 Mycobacterium avium 104 FurB protein YP_881255.1 2031994 R 243243 CDS YP_881256.1 118465187 4530384 complement(2032398..2032829) 1 NC_008595.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 2032829 4530384 MAV_2037 Mycobacterium avium 104 ArsR family transcriptional regulator YP_881256.1 2032398 R 243243 CDS YP_881257.1 118465900 4527934 2033033..2034412 1 NC_008595.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 2034412 glyS 4527934 glyS Mycobacterium avium 104 glycyl-tRNA synthetase YP_881257.1 2033033 D 243243 CDS YP_881258.1 118464811 4527630 2036403..2036624 1 NC_008595.1 hypothetical protein 2036624 4527630 MAV_2040 Mycobacterium avium 104 hypothetical protein YP_881258.1 2036403 D 243243 CDS YP_881259.1 118467214 4529595 complement(2036671..2038656) 1 NC_008595.1 identified by match to protein family HMM PF04536; hypothetical protein 2038656 4529595 MAV_2041 Mycobacterium avium 104 hypothetical protein YP_881259.1 2036671 R 243243 CDS YP_881260.1 118465200 4530397 2038800..2040071 1 NC_008595.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 2040071 4530397 MAV_2042 Mycobacterium avium 104 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_881260.1 2038800 D 243243 CDS YP_881261.1 118465876 4527518 2040139..2040756 1 NC_008595.1 identified by match to protein family HMM PF00080; [Cu-Zn] superoxide dismutase 2040756 4527518 MAV_2043 Mycobacterium avium 104 [Cu-Zn] superoxide dismutase YP_881261.1 2040139 D 243243 CDS YP_881262.1 118467186 4530157 2040798..2042750 1 NC_008595.1 synthesizes RNA primers at the replication forks; DNA primase 2042750 dnaG 4530157 dnaG Mycobacterium avium 104 DNA primase YP_881262.1 2040798 D 243243 CDS YP_881263.1 118466919 4529464 complement(2042734..2043009) 1 NC_008595.1 hypothetical protein 2043009 4529464 MAV_2044 Mycobacterium avium 104 hypothetical protein YP_881263.1 2042734 R 243243 CDS YP_881264.1 118466629 4526985 2043276..2043911 1 NC_008595.1 identified by match to protein family HMM PF02426; muconolactone delta-isomerase 2043911 4526985 MAV_2047 Mycobacterium avium 104 muconolactone delta-isomerase YP_881264.1 2043276 D 243243 CDS YP_881265.1 118463488 4529067 complement(2043916..2045307) 1 NC_008595.1 fmnh2-utilizing oxygenase 2045307 4529067 MAV_2048 Mycobacterium avium 104 fmnh2-utilizing oxygenase YP_881265.1 2043916 R 243243 CDS YP_881266.1 118462737 4527808 complement(2045304..2046425) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2046425 4527808 MAV_2049 Mycobacterium avium 104 hypothetical protein YP_881266.1 2045304 R 243243 CDS YP_881267.1 118464266 4528221 complement(2046422..2047543) 1 NC_008595.1 fmnh2-utilizing oxygenase 2047543 4528221 MAV_2050 Mycobacterium avium 104 fmnh2-utilizing oxygenase YP_881267.1 2046422 R 243243 CDS YP_881268.1 118463782 4530133 complement(2047798..2048487) 1 NC_008595.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine O-acetyltransferase 2048487 cysE 4530133 cysE Mycobacterium avium 104 serine O-acetyltransferase YP_881268.1 2047798 R 243243 CDS YP_881269.1 118465604 4527863 complement(2048489..2049421) 1 NC_008595.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 2049421 cysK 4527863 cysK Mycobacterium avium 104 cysteine synthase A YP_881269.1 2048489 R 243243 CDS YP_881270.1 118465836 4525508 complement(2049422..2050714) 1 NC_008595.1 hypothetical protein 2050714 4525508 MAV_2053 Mycobacterium avium 104 hypothetical protein YP_881270.1 2049422 R 243243 CDS YP_881271.1 118465146 4529236 2051186..2052109 1 NC_008595.1 major membrane protein 1 2052109 4529236 MAV_2054 Mycobacterium avium 104 major membrane protein 1 YP_881271.1 2051186 D 243243 CDS YP_881272.1 118463117 4527179 2052096..2054108 1 NC_008595.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; cysteine desulphurases, SufS 2054108 4527179 MAV_2055 Mycobacterium avium 104 cysteine desulphurases, SufS YP_881272.1 2052096 D 243243 CDS YP_881273.1 118462382 4529195 complement(2054132..2055265) 1 NC_008595.1 identified by match to protein family HMM PF03601; hypothetical protein 2055265 4529195 MAV_2056 Mycobacterium avium 104 hypothetical protein YP_881273.1 2054132 R 243243 CDS YP_881274.1 118464274 4528229 complement(2055262..2055420) 1 NC_008595.1 hypothetical protein 2055420 4528229 MAV_2057 Mycobacterium avium 104 hypothetical protein YP_881274.1 2055262 R 243243 CDS YP_881275.1 118463655 4525947 complement(2055538..2056314) 1 NC_008595.1 sulfotransferase 2056314 4525947 MAV_2058 Mycobacterium avium 104 sulfotransferase YP_881275.1 2055538 R 243243 CDS YP_881276.1 118466063 4530033 2056737..2057504 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB1 protein 2057504 4530033 MAV_2059 Mycobacterium avium 104 TrnB1 protein YP_881276.1 2056737 D 243243 CDS YP_881277.1 118465348 4526661 2057501..2058349 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB2 protein 2058349 4526661 MAV_2060 Mycobacterium avium 104 TrnB2 protein YP_881277.1 2057501 D 243243 CDS YP_881278.1 118467175 4530145 2058353..2059621 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2059621 4530145 MAV_2061 Mycobacterium avium 104 virulence factor Mce YP_881278.1 2058353 D 243243 CDS YP_881279.1 118466491 4527621 2059618..2060646 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2060646 4527621 MAV_2062 Mycobacterium avium 104 virulence factor Mce YP_881279.1 2059618 D 243243 CDS YP_881280.1 118466040 4528048 2060688..2061821 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2061821 4528048 MAV_2063 Mycobacterium avium 104 virulence factor Mce YP_881280.1 2060688 D 243243 CDS YP_881281.1 118465334 4526530 2061818..2063152 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2063152 4526530 MAV_2064 Mycobacterium avium 104 virulence factor Mce YP_881281.1 2061818 D 243243 CDS YP_881282.1 118464506 4525549 2063221..2063946 1 NC_008595.1 identified by match to protein family HMM PF02470; LprM protein 2063946 4525549 MAV_2065 Mycobacterium avium 104 LprM protein YP_881282.1 2063221 D 243243 CDS YP_881283.1 118464423 4530244 2063943..2064074 1 NC_008595.1 ISAfe7, transposase OrfA 2064074 4530244 MAV_2066 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_881283.1 2063943 D 243243 CDS YP_881284.1 118466567 4529116 2065031..2065621 1 NC_008595.1 LprM protein 2065621 4529116 MAV_2068 Mycobacterium avium 104 LprM protein YP_881284.1 2065031 D 243243 CDS YP_881285.1 118466763 4530758 2065630..2067090 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2067090 4530758 MAV_2069 Mycobacterium avium 104 virulence factor Mce YP_881285.1 2065630 D 243243 CDS YP_881286.1 118462830 4528644 2067105..2067716 1 NC_008595.1 hypothetical protein 2067716 4528644 MAV_2070 Mycobacterium avium 104 hypothetical protein YP_881286.1 2067105 D 243243 CDS YP_881287.1 118463090 4528913 2067713..2068288 1 NC_008595.1 hypothetical protein 2068288 4528913 MAV_2071 Mycobacterium avium 104 hypothetical protein YP_881287.1 2067713 D 243243 CDS YP_881288.1 118463678 4528525 2068292..2068792 1 NC_008595.1 hypothetical protein 2068792 4528525 MAV_2072 Mycobacterium avium 104 hypothetical protein YP_881288.1 2068292 D 243243 CDS YP_881289.1 118465533 4530008 complement(2068811..2069011) 1 NC_008595.1 hypothetical protein 2069011 4530008 MAV_2073 Mycobacterium avium 104 hypothetical protein YP_881289.1 2068811 R 243243 CDS YP_881290.1 118465227 4525598 complement(2069091..2070368) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2070368 4525598 MAV_2074 Mycobacterium avium 104 transposase, Mutator family protein YP_881290.1 2069091 R 243243 CDS YP_881291.1 118465789 4526102 complement(2070648..2074865) 1 NC_008595.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00384; match to protein family HMM PF00667; match to protein family HMM PF01568; match to protein family HMM PF04879; FdhF protein 2074865 4526102 MAV_2075 Mycobacterium avium 104 FdhF protein YP_881291.1 2070648 R 243243 CDS YP_881292.1 118464896 4529625 2075213..2075680 1 NC_008595.1 LppP protein 2075680 4529625 MAV_2076 Mycobacterium avium 104 LppP protein YP_881292.1 2075213 D 243243 CDS YP_881293.1 118463068 4527567 complement(2075816..2075935) 1 NC_008595.1 hypothetical protein 2075935 4527567 MAV_2077 Mycobacterium avium 104 hypothetical protein YP_881293.1 2075816 R 243243 CDS YP_881294.1 118464760 4527656 2075909..2077327 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 2077327 4527656 MAV_2079 Mycobacterium avium 104 transporter, major facilitator family protein YP_881294.1 2075909 D 243243 CDS YP_881295.1 118464013 4529275 complement(2077317..2079269) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF01756; match to protein family HMM PF02770; acyl-CoA oxidase 2079269 4529275 MAV_2078 Mycobacterium avium 104 acyl-CoA oxidase YP_881295.1 2077317 R 243243 CDS YP_881296.1 118462997 4530627 complement(2081676..2082203) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2082203 4530627 MAV_2081 Mycobacterium avium 104 MarR family transcriptional regulator YP_881296.1 2081676 R 243243 CDS YP_881297.1 118466336 4528767 2082385..2084346 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter 2084346 4528767 MAV_2082 Mycobacterium avium 104 ABC transporter YP_881297.1 2082385 D 243243 CDS YP_881298.1 118466723 4530661 2084343..2085197 1 NC_008595.1 identified by match to protein family HMM PF02361; cobalt transport protein 2085197 4530661 MAV_2083 Mycobacterium avium 104 cobalt transport protein YP_881298.1 2084343 D 243243 CDS YP_881299.1 118465411 4525672 complement(2085222..2085668) 1 NC_008595.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 2085668 4525672 MAV_2084 Mycobacterium avium 104 AsnC family transcriptional regulator YP_881299.1 2085222 R 243243 CDS YP_881300.1 118464106 4525867 2085805..2086659 1 NC_008595.1 identified by match to protein family HMM PF02274; amidinotransferase 2086659 4525867 MAV_2085 Mycobacterium avium 104 amidinotransferase YP_881300.1 2085805 D 243243 CDS YP_881301.1 118465731 4525693 2086656..2087894 1 NC_008595.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR01885; ornithine--oxo-acid transaminase 2087894 rocD 4525693 rocD Mycobacterium avium 104 ornithine--oxo-acid transaminase YP_881301.1 2086656 D 243243 CDS YP_881302.1 118465241 4525612 2087989..2089374 1 NC_008595.1 identified by match to protein family HMM PF00324; amino acid transporter 2089374 4525612 MAV_2087 Mycobacterium avium 104 amino acid transporter YP_881302.1 2087989 D 243243 CDS YP_881303.1 118466829 4527395 complement(2089380..2090720) 1 NC_008595.1 identified by match to protein family HMM PF01547; extracellular solute-binding protein 2090720 4527395 MAV_2088 Mycobacterium avium 104 extracellular solute-binding protein YP_881303.1 2089380 R 243243 CDS YP_881304.1 118466113 4529746 complement(2090717..2091544) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 2091544 uspE 4529746 uspE Mycobacterium avium 104 ABC transporter permease YP_881304.1 2090717 R 243243 CDS YP_881305.1 118465669 4526741 complement(2091531..2092415) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 2092415 uspA 4526741 uspA Mycobacterium avium 104 ABC transporter permease YP_881305.1 2091531 R 243243 CDS YP_881306.1 118466715 4529722 2092474..2093991 1 NC_008595.1 identified by match to protein family HMM PF01523; modulator of DNA gyrase 2093991 4529722 MAV_2091 Mycobacterium avium 104 modulator of DNA gyrase YP_881306.1 2092474 D 243243 CDS YP_881307.1 118466183 4526214 2093988..2095361 1 NC_008595.1 CalR5 protein 2095361 4526214 MAV_2092 Mycobacterium avium 104 CalR5 protein YP_881307.1 2093988 D 243243 CDS YP_881308.1 118466572 4527361 2095402..2096268 1 NC_008595.1 hypothetical protein 2096268 4527361 MAV_2093 Mycobacterium avium 104 hypothetical protein YP_881308.1 2095402 D 243243 CDS YP_881309.1 118466809 4529056 2096523..2096945 1 NC_008595.1 hypothetical protein 2096945 4529056 MAV_2094 Mycobacterium avium 104 hypothetical protein YP_881309.1 2096523 D 243243 CDS YP_881310.1 118466103 4527732 2097261..2097608 1 NC_008595.1 hypothetical protein 2097608 4527732 MAV_2095 Mycobacterium avium 104 hypothetical protein YP_881310.1 2097261 D 243243 CDS YP_881311.1 118463334 4529204 complement(2097907..2098518) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 2098518 4529204 MAV_2097 Mycobacterium avium 104 transcriptional regulator YP_881311.1 2097907 R 243243 CDS YP_881312.1 118462787 4525755 2098610..2099455 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 2099455 4525755 MAV_2098 Mycobacterium avium 104 short chain dehydrogenase YP_881312.1 2098610 D 243243 CDS YP_881313.1 118466466 4528688 2099558..2100883 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2100883 4528688 MAV_2100 Mycobacterium avium 104 transposase, Mutator family protein YP_881313.1 2099558 D 243243 CDS YP_881314.1 118466951 4530263 complement(2101281..2102687) 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 2102687 4530263 MAV_2101 Mycobacterium avium 104 aldehyde dehydrogenase YP_881314.1 2101281 R 243243 CDS YP_881315.1 118462399 4525943 2102894..2103811 1 NC_008595.1 hypothetical protein 2103811 4525943 MAV_2102 Mycobacterium avium 104 hypothetical protein YP_881315.1 2102894 D 243243 CDS YP_881316.1 118464602 4530113 complement(2105517..2107133) 1 NC_008595.1 identified by match to protein family HMM PF07690; major facilitator superfamily protein MFS_1 2107133 4530113 MAV_2104 Mycobacterium avium 104 major facilitator superfamily protein MFS_1 YP_881316.1 2105517 R 243243 CDS YP_881317.1 118465849 4530642 complement(2107360..2108049) 1 NC_008595.1 hypothetical protein 2108049 4530642 MAV_2105 Mycobacterium avium 104 hypothetical protein YP_881317.1 2107360 R 243243 CDS YP_881318.1 118464047 4529019 complement(2116479..2116637) 1 NC_008595.1 hypothetical protein 2116637 4529019 MAV_2107 Mycobacterium avium 104 hypothetical protein YP_881318.1 2116479 R 243243 CDS YP_881319.1 118463715 4528065 2116632..2119139 1 NC_008595.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07228; stage II sporulation protein E (SpoIIE) 2119139 4528065 MAV_2108 Mycobacterium avium 104 stage II sporulation protein E (SpoIIE) YP_881319.1 2116632 D 243243 CDS YP_881320.1 118464190 4529301 2119139..2119468 1 NC_008595.1 identified by match to protein family HMM PF01740; StaS domain-containing protein 2119468 4529301 MAV_2109 Mycobacterium avium 104 StaS domain-containing protein YP_881320.1 2119139 D 243243 CDS YP_881321.1 118462310 4529628 2120140..2121072 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 2121072 4529628 MAV_2110 Mycobacterium avium 104 methyltransferase, putative, family protein YP_881321.1 2120140 D 243243 CDS YP_881322.1 118462722 4530096 2121069..2121707 1 NC_008595.1 identified by match to protein family HMM PF01209; methyltransferase, UbiE/COQ5 family protein 2121707 4530096 MAV_2111 Mycobacterium avium 104 methyltransferase, UbiE/COQ5 family protein YP_881322.1 2121069 D 243243 CDS YP_881323.1 118465655 4526727 2122193..2122558 1 NC_008595.1 hypothetical protein 2122558 4526727 MAV_2113 Mycobacterium avium 104 hypothetical protein YP_881323.1 2122193 D 243243 CDS YP_881324.1 118466010 4528455 2122688..2123401 1 NC_008595.1 identified by match to protein family HMM PF01988; mebrane associated protein 2123401 4528455 MAV_2114 Mycobacterium avium 104 mebrane associated protein YP_881324.1 2122688 D 243243 CDS YP_881325.1 118465643 4526168 2123500..2124351 1 NC_008595.1 hypothetical protein 2124351 4526168 MAV_2115 Mycobacterium avium 104 hypothetical protein YP_881325.1 2123500 D 243243 CDS YP_881326.1 118466205 4530195 2124348..2125880 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-binding enzyme, putative 2125880 4530195 MAV_2116 Mycobacterium avium 104 AMP-binding enzyme, putative YP_881326.1 2124348 D 243243 CDS YP_881327.1 118466767 4530762 complement(2126008..2126628) 1 NC_008595.1 identified by match to protein family HMM TIGR03083; match to protein family HMM TIGR03085; hypothetical protein 2126628 4530762 MAV_2117 Mycobacterium avium 104 hypothetical protein YP_881327.1 2126008 R 243243 CDS YP_881328.1 118462838 4528653 2126713..2128647 1 NC_008595.1 molecular chaperone; heat shock protein 90 2128647 4528653 MAV_2118 Mycobacterium avium 104 heat shock protein 90 YP_881328.1 2126713 D 243243 CDS YP_881329.1 118463400 4528027 2128717..2128932 1 NC_008595.1 hypothetical protein 2128932 4528027 MAV_2119 Mycobacterium avium 104 hypothetical protein YP_881329.1 2128717 D 243243 CDS YP_881330.1 118464579 4530283 2129033..2130058 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2130058 4530283 MAV_2121 Mycobacterium avium 104 hypothetical protein YP_881330.1 2129033 D 243243 CDS YP_881331.1 118463975 4527222 complement(2130048..2131703) 1 NC_008595.1 identified by match to protein family HMM PF01566; Mn2+/Fe2+ transporter 2131703 4527222 MAV_2120 Mycobacterium avium 104 Mn2+/Fe2+ transporter YP_881331.1 2130048 R 243243 CDS YP_881332.1 118465092 4529982 complement(2131700..2133022) 1 NC_008595.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03448; MgtE intracellular domain-contain protein 2133022 4529982 MAV_2122 Mycobacterium avium 104 MgtE intracellular domain-contain protein YP_881332.1 2131700 R 243243 CDS YP_881333.1 118465671 4526743 complement(2133191..2133934) 1 NC_008595.1 PknM protein 2133934 4526743 MAV_2123 Mycobacterium avium 104 PknM protein YP_881333.1 2133191 R 243243 CDS YP_881334.1 118466179 4526210 2134075..2134434 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 2134434 4526210 MAV_2124 Mycobacterium avium 104 glyoxalase YP_881334.1 2134075 D 243243 CDS YP_881335.1 118463565 4530720 complement(2134435..2135331) 1 NC_008595.1 hypothetical protein 2135331 4530720 MAV_2125 Mycobacterium avium 104 hypothetical protein YP_881335.1 2134435 R 243243 CDS YP_881336.1 118464343 4529145 complement(2135385..2135777) 1 NC_008595.1 membrane protein 2135777 4529145 MAV_2126 Mycobacterium avium 104 membrane protein YP_881336.1 2135385 R 243243 CDS YP_881337.1 118465240 4525611 2135984..2137159 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA C-acyltransferase 2137159 4525611 MAV_2127 Mycobacterium avium 104 acetyl-CoA C-acyltransferase YP_881337.1 2135984 D 243243 CDS YP_881338.1 118465790 4526103 complement(2137167..2137721) 1 NC_008595.1 hypothetical protein 2137721 4526103 MAV_2128 Mycobacterium avium 104 hypothetical protein YP_881338.1 2137167 R 243243 CDS YP_881339.1 118465175 4528665 2137884..2138612 1 NC_008595.1 identified by similarity to SP:P22255; match to protein family HMM PF00459; 3'(2'),5'-bisphosphate nucleotidase, putative 2138612 4528665 MAV_2129 Mycobacterium avium 104 3'(2'),5'-bisphosphate nucleotidase, putative YP_881339.1 2137884 D 243243 CDS YP_881340.1 118465793 4526106 complement(2138689..2139621) 1 NC_008595.1 identified by match to protein family HMM PF00561; haloalkane dehalogenase 2139621 4526106 MAV_2130 Mycobacterium avium 104 haloalkane dehalogenase YP_881340.1 2138689 R 243243 CDS YP_881341.1 118462909 4528172 2139708..2140436 1 NC_008595.1 hypothetical protein 2140436 4528172 MAV_2131 Mycobacterium avium 104 hypothetical protein YP_881341.1 2139708 D 243243 CDS YP_881342.1 118467195 4528429 complement(2140451..2141656) 1 NC_008595.1 identified by match to protein family HMM PF00155; transferase 2141656 4528429 MAV_2132 Mycobacterium avium 104 transferase YP_881342.1 2140451 R 243243 CDS YP_881343.1 118464385 4528274 2141809..2142786 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2142786 4528274 MAV_2133 Mycobacterium avium 104 hypothetical protein YP_881343.1 2141809 D 243243 CDS YP_881344.1 118462345 4525690 complement(2142879..2143652) 1 NC_008595.1 hypothetical protein 2143652 4525690 MAV_2134 Mycobacterium avium 104 hypothetical protein YP_881344.1 2142879 R 243243 CDS YP_881345.1 118462348 4527975 complement(2143661..2143804) 1 NC_008595.1 hypothetical protein 2143804 4527975 MAV_2135 Mycobacterium avium 104 hypothetical protein YP_881345.1 2143661 R 243243 CDS YP_881346.1 118465932 4528491 complement(2143818..2144033) 1 NC_008595.1 hypothetical protein 2144033 4528491 MAV_2136 Mycobacterium avium 104 hypothetical protein YP_881346.1 2143818 R 243243 CDS YP_881347.1 118463386 4528013 2144085..2144516 1 NC_008595.1 hypothetical protein 2144516 4528013 MAV_2137 Mycobacterium avium 104 hypothetical protein YP_881347.1 2144085 D 243243 CDS YP_881348.1 118463668 4525960 2144553..2145761 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 2145761 4525960 MAV_2138 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_881348.1 2144553 D 243243 CDS YP_881349.1 118464450 4525981 complement(2145886..2146875) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 2146875 4525981 MAV_2139 Mycobacterium avium 104 alpha/beta hydrolase YP_881349.1 2145886 R 243243 CDS YP_881350.1 118463789 4525870 complement(2146920..2147438) 1 NC_008595.1 LppO protein 2147438 4525870 MAV_2140 Mycobacterium avium 104 LppO protein YP_881350.1 2146920 R 243243 CDS YP_881351.1 118464381 4528270 complement(2147596..2148324) 1 NC_008595.1 hypothetical protein 2148324 4528270 MAV_2141 Mycobacterium avium 104 hypothetical protein YP_881351.1 2147596 R 243243 CDS YP_881352.1 118464994 4526260 complement(2148498..2149352) 1 NC_008595.1 identified by match to protein family HMM PF00581; thiosulfate sulfurtransferase 2149352 4526260 MAV_2142 Mycobacterium avium 104 thiosulfate sulfurtransferase YP_881352.1 2148498 R 243243 CDS YP_881353.1 118465703 4530325 complement(2149509..2150654) 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase 2150654 4530325 MAV_2143 Mycobacterium avium 104 glycosyl transferase YP_881353.1 2149509 R 243243 CDS YP_881354.1 118462985 4527413 complement(2150771..2151979) 1 NC_008595.1 hypothetical protein 2151979 4527413 MAV_2144 Mycobacterium avium 104 hypothetical protein YP_881354.1 2150771 R 243243 CDS YP_881355.1 118464955 4528695 complement(2151989..2153599) 1 NC_008595.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 2153599 4528695 MAV_2145 Mycobacterium avium 104 Na+/H+ antiporter YP_881355.1 2151989 R 243243 CDS YP_881356.1 118465928 4528487 2153732..2154166 1 NC_008595.1 hypothetical protein 2154166 4528487 MAV_2147 Mycobacterium avium 104 hypothetical protein YP_881356.1 2153732 D 243243 CDS YP_881357.1 118463902 4525832 complement(2154147..2155439) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 2155439 4525832 MAV_2146 Mycobacterium avium 104 alpha/beta hydrolase YP_881357.1 2154147 R 243243 CDS YP_881358.1 118464363 4530506 2155642..2155938 1 NC_008595.1 identified by match to protein family HMM PF05534; HicB family protein 2155938 4530506 MAV_2148 Mycobacterium avium 104 HicB family protein YP_881358.1 2155642 D 243243 CDS YP_881359.1 118463770 4530121 2155991..2157265 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2157265 4530121 MAV_2149 Mycobacterium avium 104 transposase, Mutator family protein YP_881359.1 2155991 D 243243 CDS YP_881360.1 118462886 4527493 complement(2157450..2157776) 1 NC_008595.1 identified by match to protein family HMM PF00037; ferredoxin 2157776 4527493 MAV_2150 Mycobacterium avium 104 ferredoxin YP_881360.1 2157450 R 243243 CDS YP_881361.1 118462246 4526932 2157993..2158940 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2158940 4526932 MAV_2151 Mycobacterium avium 104 LysR family transcriptional regulator YP_881361.1 2157993 D 243243 CDS YP_881362.1 118464829 4529734 complement(2158942..2159658) 1 NC_008595.1 identified by match to protein family HMM PF01903; hypothetical protein 2159658 4529734 MAV_2152 Mycobacterium avium 104 hypothetical protein YP_881362.1 2158942 R 243243 CDS YP_881363.1 118466676 4526626 complement(2159655..2160398) 1 NC_008595.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2160398 4526626 MAV_2153 Mycobacterium avium 104 phosphoadenosine phosphosulfate reductase YP_881363.1 2159655 R 243243 CDS YP_881364.1 118464056 4529496 complement(2160413..2162080) 1 NC_008595.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase [ferredoxin] 1 2162080 4529496 MAV_2154 Mycobacterium avium 104 sulfite reductase [ferredoxin] 1 YP_881364.1 2160413 R 243243 CDS YP_881365.1 118463935 4528115 2162081..2162215 1 NC_008595.1 hypothetical protein 2162215 4528115 MAV_2155 Mycobacterium avium 104 hypothetical protein YP_881365.1 2162081 D 243243 CDS YP_881366.1 118463470 4525523 complement(2162442..2163755) 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 2163755 4525523 MAV_2156 Mycobacterium avium 104 P450 heme-thiolate protein YP_881366.1 2162442 R 243243 CDS YP_881367.1 118466751 4526352 2163877..2164539 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2164539 4526352 MAV_2157 Mycobacterium avium 104 TetR family transcriptional regulator YP_881367.1 2163877 D 243243 CDS YP_881368.1 118466237 4526583 2164735..2166195 1 NC_008595.1 identified by match to protein family HMM PF00069; serine/threonine protein kinase 2166195 4526583 MAV_2158 Mycobacterium avium 104 serine/threonine protein kinase YP_881368.1 2164735 D 243243 CDS YP_881369.1 118466192 4530182 complement(2166394..2167641) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 2167641 4530182 MAV_2159 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_881369.1 2166394 R 243243 CDS YP_881370.1 118465612 4527871 2167605..2167949 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 2167949 4527871 MAV_2160 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_881370.1 2167605 D 243243 CDS YP_881371.1 118465056 4527032 2168027..2168866 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2168866 4527032 MAV_2161 Mycobacterium avium 104 transposase YP_881371.1 2168027 D 243243 CDS YP_881372.1 118463826 4526044 2168915..2169253 1 NC_008595.1 transposase 2169253 4526044 MAV_2163 Mycobacterium avium 104 transposase YP_881372.1 2168915 D 243243 CDS YP_881373.1 118464568 4530787 complement(2169243..2169782) 1 NC_008595.1 serine/threonine protein kinase 2169782 4530787 MAV_2162 Mycobacterium avium 104 serine/threonine protein kinase YP_881373.1 2169243 R 243243 CDS YP_881374.1 118463111 4527173 2169887..2170408 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 2170408 pcaC 4527173 pcaC Mycobacterium avium 104 hypothetical protein YP_881374.1 2169887 D 243243 CDS YP_881375.1 118466502 4525585 2170405..2170950 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 2170950 pcaC 4525585 pcaC Mycobacterium avium 104 hypothetical protein YP_881375.1 2170405 D 243243 CDS YP_881376.1 118464160 4526470 2171071..2171601 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2171601 4526470 MAV_2167 Mycobacterium avium 104 TetR family transcriptional regulator YP_881376.1 2171071 D 243243 CDS YP_881377.1 118465852 4530645 complement(2171590..2172753) 1 NC_008595.1 identified by match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 2172753 4530645 MAV_2166 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_881377.1 2171590 R 243243 CDS YP_881378.1 118463589 4529774 2172818..2173594 1 NC_008595.1 identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 2173594 4529774 MAV_2168 Mycobacterium avium 104 N-acetylmuramoyl-L-alanine amidase YP_881378.1 2172818 D 243243 CDS YP_881379.1 118462672 4530599 complement(2173607..2174365) 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase cutinase 2174365 4530599 MAV_2169 Mycobacterium avium 104 serine esterase cutinase YP_881379.1 2173607 R 243243 CDS YP_881380.1 118466921 4529467 2174601..2174843 1 NC_008595.1 acyl carrier protein 2174843 4529467 MAV_2170 Mycobacterium avium 104 acyl carrier protein YP_881380.1 2174601 D 243243 CDS YP_881381.1 118466623 4526861 2175108..2176595 1 NC_008595.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase, putative 2176595 4526861 MAV_2172 Mycobacterium avium 104 FAD dependent oxidoreductase, putative YP_881381.1 2175108 D 243243 CDS YP_881382.1 118465795 4526108 complement(2176592..2177059) 1 NC_008595.1 LppN protein 2177059 4526108 MAV_2171 Mycobacterium avium 104 LppN protein YP_881382.1 2176592 R 243243 CDS YP_881383.1 118464962 4528702 complement(2177095..2177637) 1 NC_008595.1 identified by match to protein family HMM PF07366; hypothetical protein 2177637 4528702 MAV_2173 Mycobacterium avium 104 hypothetical protein YP_881383.1 2177095 R 243243 CDS YP_881384.1 118465433 4527302 complement(2177785..2179092) 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 2179092 4527302 MAV_2174 Mycobacterium avium 104 P450 heme-thiolate protein YP_881384.1 2177785 R 243243 CDS YP_881385.1 118467057 4526513 complement(2179124..2179471) 1 NC_008595.1 hypothetical protein 2179471 4526513 MAV_2175 Mycobacterium avium 104 hypothetical protein YP_881385.1 2179124 R 243243 CDS YP_881386.1 118466991 4529518 2179548..2180645 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 2180645 dapB 4529518 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_881386.1 2179548 D 243243 CDS YP_881387.1 118465262 4527283 2180755..2182422 1 NC_008595.1 hypothetical protein 2182422 4527283 MAV_2177 Mycobacterium avium 104 hypothetical protein YP_881387.1 2180755 D 243243 CDS YP_881388.1 118464259 4527444 complement(2182435..2182782) 1 NC_008595.1 hypothetical protein 2182782 4527444 MAV_2178 Mycobacterium avium 104 hypothetical protein YP_881388.1 2182435 R 243243 CDS YP_881389.1 118463359 4529893 complement(2182874..2183941) 1 NC_008595.1 hypothetical protein 2183941 4529893 MAV_2179 Mycobacterium avium 104 hypothetical protein YP_881389.1 2182874 R 243243 CDS YP_881390.1 118463140 4529665 complement(2184034..2184660) 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 2184660 4529665 MAV_2180 Mycobacterium avium 104 metallo-beta-lactamase YP_881390.1 2184034 R 243243 CDS YP_881391.1 118467154 4527585 2185820..2186881 1 NC_008595.1 identified by match to protein family HMM PF02390; transcriptional regulator 2186881 4527585 MAV_2182 Mycobacterium avium 104 transcriptional regulator YP_881391.1 2185820 D 243243 CDS YP_881392.1 118466305 4528347 2186881..2187699 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 2187699 4528347 MAV_2183 Mycobacterium avium 104 beta-lactamase YP_881392.1 2186881 D 243243 CDS YP_881393.1 118466778 4529336 2187830..2188363 1 NC_008595.1 hypothetical protein 2188363 4529336 MAV_2185 Mycobacterium avium 104 hypothetical protein YP_881393.1 2187830 D 243243 CDS YP_881394.1 118462907 4528170 complement(2188360..2189292) 1 NC_008595.1 involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids; diacylglycerol kinase 2189292 4528170 MAV_2184 Mycobacterium avium 104 diacylglycerol kinase YP_881394.1 2188360 R 243243 CDS YP_881395.1 118462361 4527989 complement(2189289..2190899) 1 NC_008595.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; flavoprotein 2190899 4527989 MAV_2186 Mycobacterium avium 104 flavoprotein YP_881395.1 2189289 R 243243 CDS YP_881396.1 118464377 4528266 2190917..2191498 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2191498 4528266 MAV_2187 Mycobacterium avium 104 TetR family transcriptional regulator YP_881396.1 2190917 D 243243 CDS YP_881397.1 118463780 4530131 2191495..2193036 1 NC_008595.1 identified by match to protein family HMM PF01266; glycerol-3-phosphate dehydrogenase 1 2193036 4530131 MAV_2188 Mycobacterium avium 104 glycerol-3-phosphate dehydrogenase 1 YP_881397.1 2191495 D 243243 CDS YP_881398.1 118466469 4528691 2193130..2194650 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; FAD binding domain-containing protein 2194650 4528691 MAV_2189 Mycobacterium avium 104 FAD binding domain-containing protein YP_881398.1 2193130 D 243243 CDS YP_881399.1 118466865 4529817 complement(2194729..2196150) 1 NC_008595.1 identified by match to protein family HMM PF01039; propionyl-CoA carboxylase beta chain 2196150 4529817 MAV_2190 Mycobacterium avium 104 propionyl-CoA carboxylase beta chain YP_881399.1 2194729 R 243243 CDS YP_881400.2 161579550 4525825 complement(2196192..2197514) 1 NC_008595.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 2197514 4525825 MAV_2191 Mycobacterium avium 104 3-oxoacyl-(acyl carrier protein) synthase II YP_881400.2 2196192 R 243243 CDS YP_881401.2 161579549 4526235 complement(2197533..2198783) 1 NC_008595.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 2198783 4526235 MAV_2192 Mycobacterium avium 104 3-oxoacyl-(acyl carrier protein) synthase II YP_881401.2 2197533 R 243243 CDS YP_881402.1 118462988 4527417 complement(2198780..2199127) 1 NC_008595.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2199127 acpP 4527417 acpP Mycobacterium avium 104 acyl carrier protein YP_881402.1 2198780 R 243243 CDS YP_881403.1 118463362 4529896 complement(2199204..2200112) 1 NC_008595.1 malonyl CoA-acyl carrier protein transacylase 2200112 4529896 MAV_2194 Mycobacterium avium 104 malonyl CoA-acyl carrier protein transacylase YP_881403.1 2199204 R 243243 CDS YP_881404.1 118465848 4530641 complement(2200253..2201578) 1 NC_008595.1 hypothetical protein 2201578 4530641 MAV_2195 Mycobacterium avium 104 hypothetical protein YP_881404.1 2200253 R 243243 CDS YP_881405.1 118465251 4528469 complement(2201862..2204651) 1 NC_008595.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 2204651 aceE 4528469 aceE Mycobacterium avium 104 pyruvate dehydrogenase subunit E1 YP_881405.1 2201862 R 243243 CDS YP_881406.1 118463755 4527999 2204902..2205411 1 NC_008595.1 hypothetical protein 2205411 4527999 MAV_2197 Mycobacterium avium 104 hypothetical protein YP_881406.1 2204902 D 243243 CDS YP_881407.1 118465614 4527873 2205508..2205930 1 NC_008595.1 hypothetical protein 2205930 4527873 MAV_2198 Mycobacterium avium 104 hypothetical protein YP_881407.1 2205508 D 243243 CDS YP_881408.1 118462931 4526022 2205930..2206391 1 NC_008595.1 identified by match to protein family HMM PF00578; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 2206391 4526022 MAV_2199 Mycobacterium avium 104 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_881408.1 2205930 D 243243 CDS YP_881409.1 118462402 4525712 complement(2206470..2207261) 1 NC_008595.1 identified by match to protein family HMM PF01955; adenosylcobinamide amidohydrolase 2207261 4525712 MAV_2200 Mycobacterium avium 104 adenosylcobinamide amidohydrolase YP_881409.1 2206470 R 243243 CDS YP_881410.1 118467267 4527069 2207360..2208478 1 NC_008595.1 identified by match to protein family HMM PF00561; match to protein family HMM PF06441; epoxide hydrolase 2208478 4527069 MAV_2202 Mycobacterium avium 104 epoxide hydrolase YP_881410.1 2207360 D 243243 CDS YP_881411.1 118466074 4527341 complement(2208485..2209300) 1 NC_008595.1 hypothetical protein 2209300 4527341 MAV_2203 Mycobacterium avium 104 hypothetical protein YP_881411.1 2208485 R 243243 CDS YP_881412.1 118466705 4529712 2209353..2210297 1 NC_008595.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 2210297 cobD 4529712 cobD Mycobacterium avium 104 cobalamin biosynthesis protein YP_881412.1 2209353 D 243243 CDS YP_881413.1 118464619 4526776 complement(2210279..2211109) 1 NC_008595.1 hypothetical protein 2211109 4526776 MAV_2204 Mycobacterium avium 104 hypothetical protein YP_881413.1 2210279 R 243243 CDS YP_881414.1 118463419 4530056 complement(2211109..2211600) 1 NC_008595.1 identified by match to protein family HMM PF01451; low molecular weight protein-tyrosine-phosphatase 2211600 4530056 MAV_2206 Mycobacterium avium 104 low molecular weight protein-tyrosine-phosphatase YP_881414.1 2211109 R 243243 CDS YP_881415.1 118465622 4528738 complement(2211593..2212261) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; hypothetical protein 2212261 4528738 MAV_2207 Mycobacterium avium 104 hypothetical protein YP_881415.1 2211593 R 243243 CDS YP_881416.1 118465077 4525894 2212352..2213380 1 NC_008595.1 identified by match to protein family HMM PF00155; hypothetical protein 2213380 4525894 MAV_2208 Mycobacterium avium 104 hypothetical protein YP_881416.1 2212352 D 243243 CDS YP_881417.1 118464583 4530287 2213377..2214513 1 NC_008595.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 2214513 4530287 MAV_2209 Mycobacterium avium 104 hypothetical protein YP_881417.1 2213377 D 243243 CDS YP_881418.1 118463992 4530351 2214510..2215247 1 NC_008595.1 identified by match to protein family HMM PF02591; hypothetical protein 2215247 4530351 MAV_2210 Mycobacterium avium 104 hypothetical protein YP_881418.1 2214510 D 243243 CDS YP_881419.1 118466196 4530186 2215244..2216395 1 NC_008595.1 identified by match to protein family HMM PF00075; match to protein family HMM PF00300; bifunctional RNase H/acid phosphatase 2216395 4530186 MAV_2211 Mycobacterium avium 104 bifunctional RNase H/acid phosphatase YP_881419.1 2215244 D 243243 CDS YP_881420.1 118465105 4529996 complement(2216639..2217808) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 2217808 4529996 MAV_2213 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_881420.1 2216639 R 243243 CDS YP_881421.1 118464880 4529609 complement(2217856..2218425) 1 NC_008595.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; regulatory protein 2218425 4529609 MAV_2214 Mycobacterium avium 104 regulatory protein YP_881421.1 2217856 R 243243 CDS YP_881422.1 118464057 4529497 2218472..2219122 1 NC_008595.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03848; match to protein family HMM PF05724; CheR methyltransferase SAM binding domain-containing protein 2219122 cheR 4529497 cheR Mycobacterium avium 104 CheR methyltransferase SAM binding domain-containing protein YP_881422.1 2218472 D 243243 CDS YP_881423.1 118464296 4529584 complement(2219107..2219826) 1 NC_008595.1 hypothetical protein 2219826 4529584 MAV_2215 Mycobacterium avium 104 hypothetical protein YP_881423.1 2219107 R 243243 CDS YP_881424.1 118463502 4527682 complement(2220320..2221468) 1 NC_008595.1 identified by match to protein family HMM PF00589; integrase fusion protein 2221468 4527682 MAV_2217 Mycobacterium avium 104 integrase fusion protein YP_881424.1 2220320 R 243243 CDS YP_881425.1 118464194 4529305 2221770..2221979 1 NC_008595.1 hypothetical protein 2221979 4529305 MAV_2218 Mycobacterium avium 104 hypothetical protein YP_881425.1 2221770 D 243243 CDS YP_881426.1 118462606 4528510 2222134..2222484 1 NC_008595.1 hypothetical protein 2222484 4528510 MAV_2219 Mycobacterium avium 104 hypothetical protein YP_881426.1 2222134 D 243243 CDS YP_881427.1 118466230 4526576 complement(2222704..2224029) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2224029 4526576 MAV_2220 Mycobacterium avium 104 transposase, Mutator family protein YP_881427.1 2222704 R 243243 CDS YP_881428.1 118462766 4527263 2224077..2224430 1 NC_008595.1 transposase 2224430 4527263 MAV_2221 Mycobacterium avium 104 transposase YP_881428.1 2224077 D 243243 CDS YP_881429.1 118466779 4529337 complement(2226224..2227528) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2227528 4529337 MAV_2223 Mycobacterium avium 104 transposase, Mutator family protein YP_881429.1 2226224 R 243243 CDS YP_881430.1 118463002 4530632 complement(2228526..2230199) 1 NC_008595.1 identified by match to protein family HMM PF07669; type III restriction system endonuclease, putative 2230199 4530632 MAV_2225 Mycobacterium avium 104 type III restriction system endonuclease, putative YP_881430.1 2228526 R 243243 CDS YP_881431.1 118466632 4526988 complement(2230196..2230432) 1 NC_008595.1 type III restriction system methylase 2230432 4526988 MAV_2226 Mycobacterium avium 104 type III restriction system methylase YP_881431.1 2230196 R 243243 CDS YP_881432.1 118467236 4529793 2231000..2232325 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2232325 4529793 MAV_2227 Mycobacterium avium 104 transposase, Mutator family protein YP_881432.1 2231000 D 243243 CDS YP_881433.1 118465276 4527297 2232453..2233265 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2233265 4527297 MAV_2228 Mycobacterium avium 104 transposase, Mutator family protein YP_881433.1 2232453 D 243243 CDS YP_881434.1 118465846 4530639 2233374..2234678 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2234678 4530639 MAV_2229 Mycobacterium avium 104 transposase, Mutator family protein YP_881434.1 2233374 D 243243 CDS YP_881435.1 118462670 4529098 2234810..2236084 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2236084 4529098 MAV_2230 Mycobacterium avium 104 transposase, Mutator family protein YP_881435.1 2234810 D 243243 CDS YP_881436.1 118464717 4529404 2236157..2236627 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2236627 4529404 MAV_2231 Mycobacterium avium 104 transposase, Mutator family protein YP_881436.1 2236157 D 243243 CDS YP_881437.1 118462819 4529039 2237339..2238490 1 NC_008595.1 hypothetical protein 2238490 4529039 MAV_2232 Mycobacterium avium 104 hypothetical protein YP_881437.1 2237339 D 243243 CDS YP_881438.1 118462919 4526010 2238755..2239840 1 NC_008595.1 hypothetical protein 2239840 4526010 MAV_2233 Mycobacterium avium 104 hypothetical protein YP_881438.1 2238755 D 243243 CDS YP_881439.1 118466223 4528903 2239889..2241163 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2241163 4528903 MAV_2234 Mycobacterium avium 104 transposase, Mutator family protein YP_881439.1 2239889 D 243243 CDS YP_881440.1 118464063 4529503 complement(2241608..2243248) 1 NC_008595.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235; adenylate cyclase, putative 2243248 4529503 MAV_2235 Mycobacterium avium 104 adenylate cyclase, putative YP_881440.1 2241608 R 243243 CDS YP_881441.1 118466768 4530763 complement(2243364..2243615) 1 NC_008595.1 hypothetical protein 2243615 4530763 MAV_2236 Mycobacterium avium 104 hypothetical protein YP_881441.1 2243364 R 243243 CDS YP_881442.1 118466079 4527347 2243815..2244219 1 NC_008595.1 hypothetical protein 2244219 4527347 MAV_2237 Mycobacterium avium 104 hypothetical protein YP_881442.1 2243815 D 243243 CDS YP_881443.1 118465863 4527505 complement(2245609..2246466) 1 NC_008595.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2246466 panB 4527505 panB Mycobacterium avium 104 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_881443.1 2245609 R 243243 CDS YP_881444.1 118465654 4526179 2246608..2248008 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 2248008 4526179 MAV_2240 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_881444.1 2246608 D 243243 CDS YP_881445.1 118465259 4528479 2248060..2249622 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 2249622 4528479 MAV_2241 Mycobacterium avium 104 alpha/beta hydrolase YP_881445.1 2248060 D 243243 CDS YP_881446.1 118465802 4526115 2249616..2249735 1 NC_008595.1 hypothetical protein 2249735 4526115 MAV_2242 Mycobacterium avium 104 hypothetical protein YP_881446.1 2249616 D 243243 CDS YP_881447.1 118464009 4529271 2249782..2251341 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 2251341 4529271 MAV_2243 Mycobacterium avium 104 alpha/beta hydrolase YP_881447.1 2249782 D 243243 CDS YP_881448.1 118464407 4530801 2251424..2252764 1 NC_008595.1 identified by similarity to SP:P12425; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 2252764 glnA 4530801 glnA Mycobacterium avium 104 glutamine synthetase, type I YP_881448.1 2251424 D 243243 CDS YP_881449.1 118466976 4530375 2252830..2255826 1 NC_008595.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 2255826 4530375 MAV_2245 Mycobacterium avium 104 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_881449.1 2252830 D 243243 CDS YP_881450.1 118464867 4530703 2255844..2256467 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 2256467 4530703 MAV_2246 Mycobacterium avium 104 thioesterase YP_881450.1 2255844 D 243243 CDS YP_881451.1 118462547 4530548 2256464..2257324 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2257324 4530548 MAV_2247 Mycobacterium avium 104 hypothetical protein YP_881451.1 2256464 D 243243 CDS YP_881452.1 118465638 4526163 complement(2257897..2258457) 1 NC_008595.1 hypothetical protein 2258457 4526163 MAV_2248 Mycobacterium avium 104 hypothetical protein YP_881452.1 2257897 R 243243 CDS YP_881453.1 118463915 4525846 2258710..2259093 1 NC_008595.1 hypothetical protein 2259093 4525846 MAV_2249 Mycobacterium avium 104 hypothetical protein YP_881453.1 2258710 D 243243 CDS YP_881454.1 118463410 4530047 complement(2259120..2259542) 1 NC_008595.1 hypothetical protein 2259542 4530047 MAV_2250 Mycobacterium avium 104 hypothetical protein YP_881454.1 2259120 R 243243 CDS YP_881455.1 118466280 4527833 complement(2259543..2260010) 1 NC_008595.1 hypothetical protein 2260010 4527833 MAV_2251 Mycobacterium avium 104 hypothetical protein YP_881455.1 2259543 R 243243 CDS YP_881456.1 118466938 4527773 complement(2260387..2260599) 1 NC_008595.1 hypothetical protein 2260599 4527773 MAV_2252 Mycobacterium avium 104 hypothetical protein YP_881456.1 2260387 R 243243 CDS YP_881457.1 118467080 4526380 2260810..2260971 1 NC_008595.1 hypothetical protein 2260971 4526380 MAV_2253 Mycobacterium avium 104 hypothetical protein YP_881457.1 2260810 D 243243 CDS YP_881458.1 118466269 4527821 2260972..2262036 1 NC_008595.1 hypothetical protein 2262036 4527821 MAV_2254 Mycobacterium avium 104 hypothetical protein YP_881458.1 2260972 D 243243 CDS YP_881459.1 118464878 4529607 2262112..2262303 1 NC_008595.1 hypothetical protein 2262303 4529607 MAV_2255 Mycobacterium avium 104 hypothetical protein YP_881459.1 2262112 D 243243 CDS YP_881460.1 118466942 4527777 2262448..2262837 1 NC_008595.1 gp108 protein 2262837 4527777 MAV_2256 Mycobacterium avium 104 gp108 protein YP_881460.1 2262448 D 243243 CDS YP_881461.1 118465572 4526758 complement(2263587..2263802) 1 NC_008595.1 hypothetical protein 2263802 4526758 MAV_2257 Mycobacterium avium 104 hypothetical protein YP_881461.1 2263587 R 243243 CDS YP_881462.1 118464830 4529735 complement(2263879..2265204) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2265204 4529735 MAV_2258 Mycobacterium avium 104 transposase, Mutator family protein YP_881462.1 2263879 R 243243 CDS YP_881463.1 118465516 4528933 complement(2265246..2265518) 1 NC_008595.1 hypothetical protein 2265518 4528933 MAV_2259 Mycobacterium avium 104 hypothetical protein YP_881463.1 2265246 R 243243 CDS YP_881464.1 118464620 4526777 2265779..2266129 1 NC_008595.1 serine/threonine protein kinase 2266129 4526777 MAV_2260 Mycobacterium avium 104 serine/threonine protein kinase YP_881464.1 2265779 D 243243 CDS YP_881465.1 118463260 4528125 2267086..2267430 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 2267430 4528125 MAV_2261 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_881465.1 2267086 D 243243 CDS YP_881466.1 118467112 4526374 2267508..2268347 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2268347 4526374 MAV_2262 Mycobacterium avium 104 transposase YP_881466.1 2267508 D 243243 CDS YP_881467.1 118462275 4529280 complement(2269209..2269544) 1 NC_008595.1 hypothetical protein 2269544 4529280 MAV_2263 Mycobacterium avium 104 hypothetical protein YP_881467.1 2269209 R 243243 CDS YP_881468.1 118462727 4527798 complement(2269541..2269735) 1 NC_008595.1 hypothetical protein 2269735 4527798 MAV_2264 Mycobacterium avium 104 hypothetical protein YP_881468.1 2269541 R 243243 CDS YP_881469.1 118462695 4526675 2269834..2270418 1 NC_008595.1 identified by match to protein family HMM PF01381; prophage regulatory ptotein 2270418 4526675 MAV_2265 Mycobacterium avium 104 prophage regulatory ptotein YP_881469.1 2269834 D 243243 CDS YP_881470.1 118463716 4528066 2270402..2271610 1 NC_008595.1 identified by match to protein family HMM PF00589; phage-related integrase 2271610 4528066 MAV_2266 Mycobacterium avium 104 phage-related integrase YP_881470.1 2270402 D 243243 CDS YP_881471.1 118464473 4527066 complement(2271617..2273053) 1 NC_008595.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 2273053 glnA 4527066 glnA Mycobacterium avium 104 glutamine synthetase, type I YP_881471.1 2271617 R 243243 CDS YP_881472.1 118462888 4527495 2273298..2273720 1 NC_008595.1 identified by match to protein family HMM PF06271; RDD family protein, putative 2273720 4527495 MAV_2268 Mycobacterium avium 104 RDD family protein, putative YP_881472.1 2273298 D 243243 CDS YP_881473.1 118463804 4525886 complement(2273779..2274531) 1 NC_008595.1 integral membrane protein 2274531 4525886 MAV_2269 Mycobacterium avium 104 integral membrane protein YP_881473.1 2273779 R 243243 CDS YP_881474.1 118464691 4527880 complement(2274560..2275483) 1 NC_008595.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2275483 lipA 4527880 lipA Mycobacterium avium 104 lipoyl synthase YP_881474.1 2274560 R 243243 CDS YP_881475.1 118464943 4528204 complement(2275480..2276181) 1 NC_008595.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 2276181 lipB 4528204 lipB Mycobacterium avium 104 lipoate-protein ligase B YP_881475.1 2275480 R 243243 CDS YP_881476.1 118465437 4527306 complement(2276231..2277154) 1 NC_008595.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01777; hypothetical protein 2277154 4527306 MAV_2272 Mycobacterium avium 104 hypothetical protein YP_881476.1 2276231 R 243243 CDS YP_881477.1 118464662 4528259 complement(2277171..2278961) 1 NC_008595.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927; dihydrolipoamide acetyltransferase 2278961 sucB 4528259 sucB Mycobacterium avium 104 dihydrolipoamide acetyltransferase YP_881477.1 2277171 R 243243 CDS YP_881478.1 118463162 4529863 complement(2279041..2279202) 1 NC_008595.1 hypothetical protein 2279202 4529863 MAV_2274 Mycobacterium avium 104 hypothetical protein YP_881478.1 2279041 R 243243 CDS YP_881479.1 118464693 4527882 2279185..2280963 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00561; short chain dehydrogenase 2280963 4527882 MAV_2275 Mycobacterium avium 104 short chain dehydrogenase YP_881479.1 2279185 D 243243 CDS YP_881480.1 118465784 4526919 complement(2281007..2281348) 1 NC_008595.1 hypothetical protein 2281348 4526919 MAV_2276 Mycobacterium avium 104 hypothetical protein YP_881480.1 2281007 R 243243 CDS YP_881481.1 118465065 4527041 2281497..2281946 1 NC_008595.1 hypothetical protein 2281946 4527041 MAV_2277 Mycobacterium avium 104 hypothetical protein YP_881481.1 2281497 D 243243 CDS YP_881482.1 118466454 4528675 complement(2282020..2282136) 1 NC_008595.1 hypothetical protein 2282136 4528675 MAV_2278 Mycobacterium avium 104 hypothetical protein YP_881482.1 2282020 R 243243 CDS YP_881483.1 118467168 4527600 complement(2282147..2283703) 1 NC_008595.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 2283703 4527600 MAV_2279 Mycobacterium avium 104 leucyl aminopeptidase YP_881483.1 2282147 R 243243 CDS YP_881484.1 118462423 4528286 2283745..2284848 1 NC_008595.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 2284848 gcvT 4528286 gcvT Mycobacterium avium 104 glycine cleavage system aminomethyltransferase T YP_881484.1 2283745 D 243243 CDS YP_881485.1 118463132 4529657 2284903..2286018 1 NC_008595.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2286018 ilvE 4529657 ilvE Mycobacterium avium 104 branched-chain amino acid aminotransferase YP_881485.1 2284903 D 243243 CDS YP_881486.1 118463547 4526814 complement(2286191..2286946) 1 NC_008595.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2286946 cobS 4526814 cobS Mycobacterium avium 104 cobalamin synthase YP_881486.1 2286191 R 243243 CDS YP_881487.1 118463522 4526827 complement(2286943..2287992) 1 NC_008595.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2287992 cobT 4526827 cobT Mycobacterium avium 104 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_881487.1 2286943 R 243243 CDS YP_881488.1 118463713 4528063 complement(2287992..2288528) 1 NC_008595.1 identified by match to protein family HMM PF02283; cobinamide kinase / cobinamide phosphate guanyltransferase 2288528 cobU 4528063 cobU Mycobacterium avium 104 cobinamide kinase / cobinamide phosphate guanyltransferase YP_881488.1 2287992 R 243243 CDS YP_881489.1 118463892 4530569 complement(2288556..2289248) 1 NC_008595.1 hypothetical protein 2289248 4530569 MAV_2285 Mycobacterium avium 104 hypothetical protein YP_881489.1 2288556 R 243243 CDS YP_881490.1 118466021 4529907 2289452..2290516 1 NC_008595.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase subfamily protein 2290516 4529907 MAV_2286 Mycobacterium avium 104 glycerate kinase subfamily protein YP_881490.1 2289452 D 243243 CDS YP_881491.1 118465196 4530393 2290614..2290970 1 NC_008595.1 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein 2290970 4530393 MAV_2287 Mycobacterium avium 104 HesB/YadR/YfhF family protein YP_881491.1 2290614 D 243243 CDS YP_881492.1 118466864 4529816 complement(2290997..2291674) 1 NC_008595.1 hypothetical protein 2291674 4529816 MAV_2288 Mycobacterium avium 104 hypothetical protein YP_881492.1 2290997 R 243243 CDS YP_881493.1 118464991 4527483 2291854..2292828 1 NC_008595.1 identified by match to protein family HMM PF00294; adenosine kinase 2292828 4527483 MAV_2289 Mycobacterium avium 104 adenosine kinase YP_881493.1 2291854 D 243243 CDS YP_881494.1 118465242 4525613 complement(2292850..2294781) 1 NC_008595.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536; asparagine synthase (glutamine-hydrolyzing) 2294781 asnB 4525613 asnB Mycobacterium avium 104 asparagine synthase (glutamine-hydrolyzing) YP_881494.1 2292850 R 243243 CDS YP_881495.1 118467069 4526447 2294975..2295985 1 NC_008595.1 identified by match to protein family HMM PF00116; cytochrome C oxidase, subunit 2 2295985 4526447 MAV_2291 Mycobacterium avium 104 cytochrome C oxidase, subunit 2 YP_881495.1 2294975 D 243243 CDS YP_881496.1 118466685 4530427 2295999..2296418 1 NC_008595.1 cytochrome C oxidase polypeptide 4 2296418 4530427 MAV_2292 Mycobacterium avium 104 cytochrome C oxidase polypeptide 4 YP_881496.1 2295999 D 243243 CDS YP_881497.1 118463396 4528023 2296608..2297408 1 NC_008595.1 MmpS3 protein 2297408 4528023 MAV_2293 Mycobacterium avium 104 MmpS3 protein YP_881497.1 2296608 D 243243 CDS YP_881498.1 118464217 4526897 2297408..2298040 1 NC_008595.1 hypothetical protein 2298040 4526897 MAV_2294 Mycobacterium avium 104 hypothetical protein YP_881498.1 2297408 D 243243 CDS YP_881499.1 118466819 4527384 2298223..2298666 1 NC_008595.1 hypothetical protein 2298666 4527384 MAV_2295 Mycobacterium avium 104 hypothetical protein YP_881499.1 2298223 D 243243 CDS YP_881500.1 118465099 4529990 complement(2298701..2300401) 1 NC_008595.1 petB; identified by match to protein family HMM PF00033; cytochrome b6 2300401 4529990 MAV_2296 Mycobacterium avium 104 cytochrome b6 YP_881500.1 2298701 R 243243 CDS YP_881501.1 118466759 4530754 complement(2300398..2301603) 1 NC_008595.1 identified by match to protein family HMM PF00355; ubiquinol-cytochrome C reductase, iron-sulfur subunit QcrA 2301603 4530754 MAV_2297 Mycobacterium avium 104 ubiquinol-cytochrome C reductase, iron-sulfur subunit QcrA YP_881501.1 2300398 R 243243 CDS YP_881502.1 118462513 4528591 complement(2301686..2302513) 1 NC_008595.1 identified by match to protein family HMM PF00034; cytochrome C 2302513 4528591 MAV_2298 Mycobacterium avium 104 cytochrome C YP_881502.1 2301686 R 243243 CDS YP_881503.1 118465650 4526175 complement(2302543..2303085) 1 NC_008595.1 identified by match to protein family HMM PF00510; cytochrome C oxidase, subunit 3 2303085 4526175 MAV_2299 Mycobacterium avium 104 cytochrome C oxidase, subunit 3 YP_881503.1 2302543 R 243243 CDS YP_881504.1 118464588 4530293 2303182..2304405 1 NC_008595.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 2304405 trpD 4530293 trpD Mycobacterium avium 104 anthranilate phosphoribosyltransferase YP_881504.1 2303182 D 243243 CDS YP_881505.1 118466522 4527195 complement(2304280..2306211) 1 NC_008595.1 contains 3'-5'exonuclease domain; hypothetical protein 2306211 4527195 MAV_2300 Mycobacterium avium 104 hypothetical protein YP_881505.1 2304280 R 243243 CDS YP_881506.1 118464069 4529509 2306257..2306430 1 NC_008595.1 hypothetical protein 2306430 4529509 MAV_2302 Mycobacterium avium 104 hypothetical protein YP_881506.1 2306257 D 243243 CDS YP_881507.1 118466071 4530041 2306424..2306618 1 NC_008595.1 hypothetical protein 2306618 4530041 MAV_2303 Mycobacterium avium 104 hypothetical protein YP_881507.1 2306424 D 243243 CDS YP_881508.1 118465429 4529978 2306928..2307956 1 NC_008595.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 2307956 4529978 MAV_2304 Mycobacterium avium 104 NLP/P60 family protein YP_881508.1 2306928 D 243243 CDS YP_881509.1 118463583 4529768 2307988..2308818 1 NC_008595.1 hypothetical protein 2308818 4529768 MAV_2305 Mycobacterium avium 104 hypothetical protein YP_881509.1 2307988 D 243243 CDS YP_881510.1 118464154 4526463 2308856..2309989 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 2309989 4526463 MAV_2306 Mycobacterium avium 104 glycosyl transferase, group 1 YP_881510.1 2308856 D 243243 CDS YP_881511.1 118465507 4526804 complement(2310149..2311951) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA dehydrogenase 2311951 4526804 MAV_2307 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881511.1 2310149 R 243243 CDS YP_881512.1 118464663 4528260 2312112..2312516 1 NC_008595.1 hypothetical protein 2312516 4528260 MAV_2308 Mycobacterium avium 104 hypothetical protein YP_881512.1 2312112 D 243243 CDS YP_881513.1 118465021 4530070 2312632..2313069 1 NC_008595.1 identified by match to protein family HMM PF03364; cyclase/dehydrase 2313069 4530070 MAV_2309 Mycobacterium avium 104 cyclase/dehydrase YP_881513.1 2312632 D 243243 CDS YP_881514.1 118463970 4527217 2313164..2314342 1 NC_008595.1 identified by match to protein family HMM PF02374; anion-transporting ATPase 2314342 4527217 MAV_2310 Mycobacterium avium 104 anion-transporting ATPase YP_881514.1 2313164 D 243243 CDS YP_881515.1 118466123 4529756 2314339..2314728 1 NC_008595.1 hypothetical protein 2314728 4529756 MAV_2311 Mycobacterium avium 104 hypothetical protein YP_881515.1 2314339 D 243243 CDS YP_881516.1 118465753 4530445 2314816..2315541 1 NC_008595.1 identified by match to protein family HMM PF01553; 1-acylglycerol-3-phosphate O-acyltransferase 2315541 4530445 MAV_2313 Mycobacterium avium 104 1-acylglycerol-3-phosphate O-acyltransferase YP_881516.1 2314816 D 243243 CDS YP_881517.1 118466800 4529046 complement(2315538..2316710) 1 NC_008595.1 hypothetical protein 2316710 4529046 MAV_2312 Mycobacterium avium 104 hypothetical protein YP_881517.1 2315538 R 243243 CDS YP_881518.1 118463447 4529689 2316934..2317803 1 NC_008595.1 hypothetical protein 2317803 4529689 MAV_2314 Mycobacterium avium 104 hypothetical protein YP_881518.1 2316934 D 243243 CDS YP_881519.1 118462769 4527266 2317824..2318312 1 NC_008595.1 hypothetical protein 2318312 4527266 MAV_2315 Mycobacterium avium 104 hypothetical protein YP_881519.1 2317824 D 243243 CDS YP_881520.1 118464370 4530513 2318404..2319792 1 NC_008595.1 identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358; 3-deoxy-7-phosphoheptulonate synthase 2319792 4530513 MAV_2317 Mycobacterium avium 104 3-deoxy-7-phosphoheptulonate synthase YP_881520.1 2318404 D 243243 CDS YP_881521.1 118463753 4527997 complement(2319789..2321234) 1 NC_008595.1 hypothetical protein 2321234 4527997 MAV_2316 Mycobacterium avium 104 hypothetical protein YP_881521.1 2319789 R 243243 CDS YP_881522.1 118466868 4529820 complement(2321369..2322655) 1 NC_008595.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; serine/threonine protein kinase 2322655 4529820 MAV_2318 Mycobacterium avium 104 serine/threonine protein kinase YP_881522.1 2321369 R 243243 CDS YP_881523.1 118464929 4528569 2322762..2323139 1 NC_008595.1 hypothetical protein 2323139 4528569 MAV_2320 Mycobacterium avium 104 hypothetical protein YP_881523.1 2322762 D 243243 CDS YP_881524.1 118465458 4526226 complement(2323133..2324650) 1 NC_008595.1 integral membrane protein 2324650 4526226 MAV_2319 Mycobacterium avium 104 integral membrane protein YP_881524.1 2323133 R 243243 CDS YP_881525.1 118464723 4529410 complement(2324655..2325704) 1 NC_008595.1 identified by match to protein family HMM PF00348; polyprenyl synthetase 2325704 4529410 MAV_2321 Mycobacterium avium 104 polyprenyl synthetase YP_881525.1 2324655 R 243243 CDS YP_881526.1 118464132 4528833 2325970..2326863 1 NC_008595.1 hypothetical protein 2326863 4528833 MAV_2322 Mycobacterium avium 104 hypothetical protein YP_881526.1 2325970 D 243243 CDS YP_881527.1 118463241 4525777 complement(2326867..2327547) 1 NC_008595.1 LppM protein 2327547 4525777 MAV_2323 Mycobacterium avium 104 LppM protein YP_881527.1 2326867 R 243243 CDS YP_881528.1 118462543 4530544 complement(2327667..2328269) 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 2328269 4530544 MAV_2324 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_881528.1 2327667 R 243243 CDS YP_881529.1 118463363 4529897 2328662..2329063 1 NC_008595.1 hypothetical protein 2329063 4529897 MAV_2325 Mycobacterium avium 104 hypothetical protein YP_881529.1 2328662 D 243243 CDS YP_881530.1 118464992 4527484 complement(2329245..2329412) 1 NC_008595.1 hypothetical protein 2329412 4527484 MAV_2326 Mycobacterium avium 104 hypothetical protein YP_881530.1 2329245 R 243243 CDS YP_881531.1 118462602 4528506 2329500..2329931 1 NC_008595.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 2329931 mraZ 4528506 mraZ Mycobacterium avium 104 cell division protein MraZ YP_881531.1 2329500 D 243243 CDS YP_881532.1 118464814 4527633 2330059..2331066 1 NC_008595.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 2331066 mraW 4527633 mraW Mycobacterium avium 104 S-adenosyl-methyltransferase MraW YP_881532.1 2330059 D 243243 CDS YP_881533.1 118466986 4529513 2331066..2332340 1 NC_008595.1 hypothetical protein 2332340 4529513 MAV_2329 Mycobacterium avium 104 hypothetical protein YP_881533.1 2331066 D 243243 CDS YP_881534.1 118466317 4528359 2332409..2334328 1 NC_008595.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin binding protein transpeptidase domain-containing protein 2334328 4528359 MAV_2330 Mycobacterium avium 104 penicillin binding protein transpeptidase domain-containing protein YP_881534.1 2332409 D 243243 CDS YP_881535.1 118462627 4526429 2334431..2335993 1 NC_008595.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2335993 murE 4526429 murE Mycobacterium avium 104 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_881535.1 2334431 D 243243 CDS YP_881536.1 118467198 4528432 2335990..2337591 1 NC_008595.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 2337591 4528432 MAV_2332 Mycobacterium avium 104 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_881536.1 2335990 D 243243 CDS YP_881537.1 118463795 4525877 2337588..2338667 1 NC_008595.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2338667 mraY 4525877 mraY Mycobacterium avium 104 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_881537.1 2337588 D 243243 CDS YP_881538.1 118463229 4528803 2338667..2340136 1 NC_008595.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2340136 murD 4528803 murD Mycobacterium avium 104 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_881538.1 2338667 D 243243 CDS YP_881539.1 118466145 4527911 2340145..2341977 1 NC_008595.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; cell division protein FtsW 2341977 ftsW 4527911 ftsW Mycobacterium avium 104 cell division protein FtsW YP_881539.1 2340145 D 243243 CDS YP_881540.1 118466852 4529804 2341974..2343200 1 NC_008595.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 2343200 murG 4529804 murG Mycobacterium avium 104 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_881540.1 2341974 D 243243 CDS YP_881541.1 118463520 4527700 2343197..2344687 1 NC_008595.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2344687 murC 4527700 murC Mycobacterium avium 104 UDP-N-acetylmuramate--L-alanine ligase YP_881541.1 2343197 D 243243 CDS YP_881542.1 118464278 4528233 2344684..2345628 1 NC_008595.1 identified by match to protein family HMM PF03799; cell division protein FtsQ-like protein 2345628 4528233 MAV_2338 Mycobacterium avium 104 cell division protein FtsQ-like protein YP_881542.1 2344684 D 243243 CDS YP_881543.1 118463876 4527754 2345631..2345792 1 NC_008595.1 FtsQ protein 2345792 4527754 MAV_2339 Mycobacterium avium 104 FtsQ protein YP_881543.1 2345631 D 243243 CDS YP_881544.1 118465296 4529332 2345899..2347059 1 NC_008595.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2347059 ftsZ 4529332 ftsZ Mycobacterium avium 104 cell division protein FtsZ YP_881544.1 2345899 D 243243 CDS YP_881545.1 118466056 4530026 2347112..2347819 1 NC_008595.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 2347819 4530026 MAV_2341 Mycobacterium avium 104 hypothetical protein YP_881545.1 2347112 D 243243 CDS YP_881546.1 118466416 4530160 2347825..2348610 1 NC_008595.1 identified by match to protein family HMM TIGR00044; hypothetical protein 2348610 4530160 MAV_2342 Mycobacterium avium 104 hypothetical protein YP_881546.1 2347825 D 243243 CDS YP_881547.1 118465048 4525827 2348722..2349321 1 NC_008595.1 identified by match to protein family HMM PF04472; hypothetical protein 2349321 4525827 MAV_2343 Mycobacterium avium 104 hypothetical protein YP_881547.1 2348722 D 243243 CDS YP_881548.1 118463067 4527566 2349434..2349781 1 NC_008595.1 transmembrane protein 2349781 4527566 MAV_2344 Mycobacterium avium 104 transmembrane protein YP_881548.1 2349434 D 243243 CDS YP_881549.1 118466219 4528898 2350105..2350857 1 NC_008595.1 identified by match to protein family HMM PF05103; Wag31 protein 2350857 4528898 MAV_2345 Mycobacterium avium 104 Wag31 protein YP_881549.1 2350105 D 243243 CDS YP_881550.1 118465304 4526558 2350973..2351368 1 NC_008595.1 hypothetical protein 2351368 4526558 MAV_2346 Mycobacterium avium 104 hypothetical protein YP_881550.1 2350973 D 243243 CDS YP_881551.1 118466836 4526945 complement(2351381..2352034) 1 NC_008595.1 identified by match to protein family HMM PF00156; phosphoribosyltransferase 2352034 4526945 MAV_2347 Mycobacterium avium 104 phosphoribosyltransferase YP_881551.1 2351381 R 243243 CDS YP_881552.1 118462973 4527401 complement(2352100..2352327) 1 NC_008595.1 CalR2 protein 2352327 4527401 MAV_2348 Mycobacterium avium 104 CalR2 protein YP_881552.1 2352100 R 243243 CDS YP_881553.1 118462267 4526411 2352696..2354051 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; hypothetical protein 2354051 4526411 MAV_2350 Mycobacterium avium 104 hypothetical protein YP_881553.1 2352696 D 243243 CDS YP_881554.1 118464352 4529154 2354088..2354618 1 NC_008595.1 identified by match to protein family HMM PF01161; match to protein family HMM TIGR00481; hypothetical protein 2354618 4529154 MAV_2351 Mycobacterium avium 104 hypothetical protein YP_881554.1 2354088 D 243243 CDS YP_881555.1 118464603 4530114 2354749..2356155 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 2356155 4530114 MAV_2352 Mycobacterium avium 104 hypothetical protein YP_881555.1 2354749 D 243243 CDS YP_881556.1 118465857 4530651 complement(2356157..2357218) 1 NC_008595.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2357218 pyrD 4530651 pyrD Mycobacterium avium 104 dihydroorotate dehydrogenase 2 YP_881556.1 2356157 R 243243 CDS YP_881557.1 118465163 4529253 complement(2357266..2357535) 1 NC_008595.1 hypothetical protein 2357535 4529253 MAV_2354 Mycobacterium avium 104 hypothetical protein YP_881557.1 2357266 R 243243 CDS YP_881558.1 118466990 4529517 complement(2357532..2358551) 1 NC_008595.1 LppL protein 2358551 4529517 MAV_2355 Mycobacterium avium 104 LppL protein YP_881558.1 2357532 R 243243 CDS YP_881559.1 118466134 4527900 2358741..2359043 1 NC_008595.1 hypothetical protein 2359043 4527900 MAV_2356 Mycobacterium avium 104 hypothetical protein YP_881559.1 2358741 D 243243 CDS YP_881560.1 118464768 4529123 2359090..2359884 1 NC_008595.1 identified by match to protein family HMM PF00300; hypothetical protein 2359884 4529123 MAV_2357 Mycobacterium avium 104 hypothetical protein YP_881560.1 2359090 D 243243 CDS YP_881561.1 118464841 4527957 2359947..2360534 1 NC_008595.1 hypothetical protein 2360534 4527957 MAV_2358 Mycobacterium avium 104 hypothetical protein YP_881561.1 2359947 D 243243 CDS YP_881562.1 118462618 4526420 2360518..2361363 1 NC_008595.1 hypothetical protein 2361363 4526420 MAV_2359 Mycobacterium avium 104 hypothetical protein YP_881562.1 2360518 D 243243 CDS YP_881563.1 118463321 4529561 2361422..2362216 1 NC_008595.1 identified by match to protein family HMM PF00459; inositol monophosphatase 2362216 4529561 MAV_2360 Mycobacterium avium 104 inositol monophosphatase YP_881563.1 2361422 D 243243 CDS YP_881564.1 118465539 4530015 2362692..2363846 1 NC_008595.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2363846 cysS 4530015 cysS Mycobacterium avium 104 cysteinyl-tRNA synthetase YP_881564.1 2362692 D 243243 CDS YP_881565.1 118466286 4529532 2364590..2367265 1 NC_008595.1 identified by match to protein family HMM PF00196; TPR repeat-containing protein 2367265 4529532 MAV_2362 Mycobacterium avium 104 TPR repeat-containing protein YP_881565.1 2364590 D 243243 CDS YP_881566.1 118464816 4527635 complement(2367695..2368969) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2368969 4527635 MAV_2363 Mycobacterium avium 104 transposase, Mutator family protein YP_881566.1 2367695 R 243243 CDS YP_881567.1 118465517 4528934 2369082..2371673 1 NC_008595.1 identified by match to protein family HMM PF00196; match to protein family HMM PF07721; TPR repeat-containing protein 2371673 4528934 MAV_2364 Mycobacterium avium 104 TPR repeat-containing protein YP_881567.1 2369082 D 243243 CDS YP_881568.1 118464030 4528828 2372157..2373884 1 NC_008595.1 identified by match to protein family HMM PF02775; match to protein family HMM PF02776; acetolactate synthase 2373884 4528828 MAV_2365 Mycobacterium avium 104 acetolactate synthase YP_881568.1 2372157 D 243243 CDS YP_881569.1 118464763 4527659 2374331..2374564 1 NC_008595.1 identified by match to protein family HMM PF03621; hypothetical protein 2374564 4527659 MAV_2366 Mycobacterium avium 104 hypothetical protein YP_881569.1 2374331 D 243243 CDS YP_881570.1 118467314 4530307 2381720..2383207 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 2383207 4530307 MAV_2368 Mycobacterium avium 104 transporter, major facilitator family protein YP_881570.1 2381720 D 243243 CDS YP_881571.1 118463480 4525533 2383291..2383470 1 NC_008595.1 hypothetical protein 2383470 4525533 MAV_2369 Mycobacterium avium 104 hypothetical protein YP_881571.1 2383291 D 243243 CDS YP_881572.1 118465538 4530014 2383595..2389891 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; mycocerosic acid synthase 2389891 4530014 MAV_2370 Mycobacterium avium 104 mycocerosic acid synthase YP_881572.1 2383595 D 243243 CDS YP_881573.1 118465891 4527925 2389933..2391183 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome p450 2391183 4527925 MAV_2371 Mycobacterium avium 104 cytochrome p450 YP_881573.1 2389933 D 243243 CDS YP_881574.1 118462721 4530095 2391223..2391558 1 NC_008595.1 hypothetical protein 2391558 4530095 MAV_2372 Mycobacterium avium 104 hypothetical protein YP_881574.1 2391223 D 243243 CDS YP_881575.1 118465171 4528661 2391570..2392337 1 NC_008595.1 identified by match to protein family HMM PF00970; match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore-interacting protein 2392337 4528661 MAV_2373 Mycobacterium avium 104 siderophore-interacting protein YP_881575.1 2391570 D 243243 CDS YP_881576.1 118466796 4529042 complement(2394196..2394321) 1 NC_008595.1 hypothetical protein 2394321 4529042 MAV_2375 Mycobacterium avium 104 hypothetical protein YP_881576.1 2394196 R 243243 CDS YP_881577.1 118463268 4528133 2394818..2395717 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2395717 4528133 MAV_2376 Mycobacterium avium 104 short chain dehydrogenase YP_881577.1 2394818 D 243243 CDS YP_881578.1 118462290 4525634 2395777..2396814 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2396814 4525634 MAV_2377 Mycobacterium avium 104 transposase YP_881578.1 2395777 D 243243 CDS YP_881579.1 118466954 4530266 complement(2396849..2397751) 1 NC_008595.1 identified by match to protein family HMM PF01908; hypothetical protein 2397751 4530266 MAV_2378 Mycobacterium avium 104 hypothetical protein YP_881579.1 2396849 R 243243 CDS YP_881580.1 118464494 4525537 2398182..2401955 1 NC_008595.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 2401955 metH 4525537 metH Mycobacterium avium 104 B12-dependent methionine synthase YP_881580.1 2398182 D 243243 CDS YP_881581.1 118464068 4529508 complement(2401971..2403008) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2403008 4529508 MAV_2380 Mycobacterium avium 104 transposase YP_881581.1 2401971 R 243243 CDS YP_881582.1 118462755 4527845 complement(2403068..2403835) 1 NC_008595.1 hypothetical protein 2403835 4527845 MAV_2381 Mycobacterium avium 104 hypothetical protein YP_881582.1 2403068 R 243243 CDS YP_881583.1 118466088 4527356 complement(2404588..2405847) 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 2405847 4527356 MAV_2383 Mycobacterium avium 104 mce related protein YP_881583.1 2404588 R 243243 CDS YP_881584.1 118464806 4527625 complement(2405844..2407061) 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 2407061 4527625 MAV_2384 Mycobacterium avium 104 mce related protein YP_881584.1 2405844 R 243243 CDS YP_881585.1 118464427 4530248 complement(2407058..2408173) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2408173 4530248 MAV_2385 Mycobacterium avium 104 virulence factor Mce YP_881585.1 2407058 R 243243 CDS YP_881586.1 118463686 4528533 complement(2408170..2409210) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2409210 4528533 MAV_2386 Mycobacterium avium 104 virulence factor Mce YP_881586.1 2408170 R 243243 CDS YP_881587.1 118463303 4525998 complement(2409254..2410309) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2410309 4525998 MAV_2387 Mycobacterium avium 104 virulence factor Mce YP_881587.1 2409254 R 243243 CDS YP_881588.1 118466346 4530486 complement(2410306..2411898) 1 NC_008595.1 identified by match to protein family HMM PF02470; mce related protein 2411898 4530486 MAV_2388 Mycobacterium avium 104 mce related protein YP_881588.1 2410306 R 243243 CDS YP_881589.1 118466872 4526690 complement(2411922..2412785) 1 NC_008595.1 identified by match to protein family HMM PF02405; ABC-transporter integral membrane protein 2412785 4526690 MAV_2389 Mycobacterium avium 104 ABC-transporter integral membrane protein YP_881589.1 2411922 R 243243 CDS YP_881590.1 118462658 4529086 complement(2412787..2413647) 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 2413647 4529086 MAV_2390 Mycobacterium avium 104 hypothetical protein YP_881590.1 2412787 R 243243 CDS YP_881591.1 118463193 4527716 2413951..2414583 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2414583 4527716 MAV_2391 Mycobacterium avium 104 TetR family transcriptional regulator YP_881591.1 2413951 D 243243 CDS YP_881592.1 118463747 4528155 2414610..2414891 1 NC_008595.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2414891 hisE 4528155 hisE Mycobacterium avium 104 phosphoribosyl-ATP pyrophosphatase YP_881592.1 2414610 D 243243 CDS YP_881593.1 118464658 4528255 2414894..2415748 1 NC_008595.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2415748 hisG 4528255 hisG Mycobacterium avium 104 ATP phosphoribosyltransferase YP_881593.1 2414894 D 243243 CDS YP_881594.1 118465197 4530394 2415898..2416410 1 NC_008595.1 hypothetical protein 2416410 4530394 MAV_2394 Mycobacterium avium 104 hypothetical protein YP_881594.1 2415898 D 243243 CDS YP_881595.1 118466035 4528043 2416435..2417805 1 NC_008595.1 Enables the enzymatic reduction of mercuric ions to elemental mercury; mercuric reductase 2417805 4528043 MAV_2396 Mycobacterium avium 104 mercuric reductase YP_881595.1 2416435 D 243243 CDS YP_881596.1 118466570 4527359 complement(2417802..2418707) 1 NC_008595.1 RecB family protein exonuclease 2418707 4527359 MAV_2395 Mycobacterium avium 104 RecB family protein exonuclease YP_881596.1 2417802 R 243243 CDS YP_881597.1 118466168 4526199 2418783..2419628 1 NC_008595.1 PimT protein 2419628 4526199 MAV_2397 Mycobacterium avium 104 PimT protein YP_881597.1 2418783 D 243243 CDS YP_881598.1 118462774 4527271 complement(2419642..2419941) 1 NC_008595.1 identified by match to protein family HMM PF04456; hypothetical protein 2419941 4527271 MAV_2398 Mycobacterium avium 104 hypothetical protein YP_881598.1 2419642 R 243243 CDS YP_881599.1 118464997 4526263 complement(2419950..2420540) 1 NC_008595.1 LppK protein 2420540 4526263 MAV_2399 Mycobacterium avium 104 LppK protein YP_881599.1 2419950 R 243243 CDS YP_881600.1 118465707 4530329 2420772..2422712 1 NC_008595.1 identified by match to protein family HMM PF00004; ATPase AAA 2422712 4530329 MAV_2400 Mycobacterium avium 104 ATPase AAA YP_881600.1 2420772 D 243243 CDS YP_881601.1 118464079 4528392 complement(2422826..2423470) 1 NC_008595.1 hypothetical protein 2423470 4528392 MAV_2401 Mycobacterium avium 104 hypothetical protein YP_881601.1 2422826 R 243243 CDS YP_881602.1 118463394 4528021 2425377..2425571 1 NC_008595.1 identified by match to protein family HMM PF05639; hypothetical protein 2425571 4528021 MAV_2403 Mycobacterium avium 104 hypothetical protein YP_881602.1 2425377 D 243243 CDS YP_881603.1 118466114 4529747 2425568..2426479 1 NC_008595.1 identified by match to protein family HMM PF00227; PcrB protein 2426479 4529747 MAV_2404 Mycobacterium avium 104 PcrB protein YP_881603.1 2425568 D 243243 CDS YP_881604.1 118466837 4526946 2426476..2427246 1 NC_008595.1 identified by match to protein family HMM PF00227; peptidase, T1 family protein 2427246 4526946 MAV_2405 Mycobacterium avium 104 peptidase, T1 family protein YP_881604.1 2426476 D 243243 CDS YP_881605.1 118464998 4526264 2427374..2428732 1 NC_008595.1 identified by match to protein family HMM PF03136; match to protein family HMM PF03316; proteasome component 2428732 4526264 MAV_2406 Mycobacterium avium 104 proteasome component YP_881605.1 2427374 D 243243 CDS YP_881606.1 118463642 4528544 2428782..2429837 1 NC_008595.1 hypothetical protein 2429837 4528544 MAV_2407 Mycobacterium avium 104 hypothetical protein YP_881606.1 2428782 D 243243 CDS YP_881607.1 118464193 4529304 2429834..2430802 1 NC_008595.1 hypothetical protein 2430802 4529304 MAV_2408 Mycobacterium avium 104 hypothetical protein YP_881607.1 2429834 D 243243 CDS YP_881608.1 118466611 4526848 2430902..2431183 1 NC_008595.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 2431183 tatA 4526848 tatA Mycobacterium avium 104 twin arginine translocase protein A YP_881608.1 2430902 D 243243 CDS YP_881609.1 118467313 4530306 2431238..2432194 1 NC_008595.1 identified by match to protein family HMM PF00902; match to protein family HMM TIGR00945; twin arginine-targeting protein translocase TatC 2432194 tatC 4530306 tatC Mycobacterium avium 104 twin arginine-targeting protein translocase TatC YP_881609.1 2431238 D 243243 CDS YP_881610.1 118462890 4527497 2435140..2435817 1 NC_008595.1 hypothetical protein 2435817 4527497 MAV_2412 Mycobacterium avium 104 hypothetical protein YP_881610.1 2435140 D 243243 CDS YP_881611.1 118463818 4526074 complement(2435822..2436763) 1 NC_008595.1 identified by match to protein family HMM PF01367; match to protein family HMM PF02739; 5'-3' exonuclease 2436763 4526074 MAV_2413 Mycobacterium avium 104 5'-3' exonuclease YP_881611.1 2435822 R 243243 CDS YP_881612.1 118464411 4530805 2436896..2438023 1 NC_008595.1 identified by match to protein family HMM PF00557; proline dipeptidase 2438023 4530805 MAV_2414 Mycobacterium avium 104 proline dipeptidase YP_881612.1 2436896 D 243243 CDS YP_881613.1 118465859 4530653 2438129..2441119 1 NC_008595.1 hypothetical protein 2441119 4530653 MAV_2415 Mycobacterium avium 104 hypothetical protein YP_881613.1 2438129 D 243243 CDS YP_881614.1 118466083 4527351 2441537..2441692 1 NC_008595.1 hypothetical protein 2441692 4527351 MAV_2417 Mycobacterium avium 104 hypothetical protein YP_881614.1 2441537 D 243243 CDS YP_881615.1 118466684 4530426 2443902..2444240 1 NC_008595.1 hypothetical protein 2444240 4530426 MAV_2420 Mycobacterium avium 104 hypothetical protein YP_881615.1 2443902 D 243243 CDS YP_881616.1 118467233 4529790 complement(2444237..2444386) 1 NC_008595.1 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 2444386 4529790 MAV_2419 Mycobacterium avium 104 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_881616.1 2444237 R 243243 CDS YP_881617.1 118465648 4526173 2444950..2445303 1 NC_008595.1 hypothetical protein 2445303 4526173 MAV_2421 Mycobacterium avium 104 hypothetical protein YP_881617.1 2444950 D 243243 CDS YP_881618.1 118464145 4528847 complement(2445329..2445739) 1 NC_008595.1 identified by match to protein family HMM PF01243; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 2445739 4528847 MAV_2422 Mycobacterium avium 104 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_881618.1 2445329 R 243243 CDS YP_881619.1 118464668 4528363 2445775..2446524 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2446524 4528363 MAV_2423 Mycobacterium avium 104 short chain dehydrogenase YP_881619.1 2445775 D 243243 CDS YP_881620.1 118464970 4528710 2446571..2447740 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469; precorrin-6Y C5,15-methyltransferase (decarboxylating) 2447740 cobL 4528710 cobL Mycobacterium avium 104 precorrin-6Y C5,15-methyltransferase (decarboxylating) YP_881620.1 2446571 D 243243 CDS YP_881621.1 118464616 4526773 2447737..2448492 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C11-methyltransferase 2448492 cobM 4526773 cobM Mycobacterium avium 104 precorrin-4 C11-methyltransferase YP_881621.1 2447737 D 243243 CDS YP_881622.1 118466900 4528414 2448492..2449226 1 NC_008595.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 2449226 cobK 4528414 cobK Mycobacterium avium 104 cobalt-precorrin-6x reductase YP_881622.1 2448492 D 243243 CDS YP_881623.1 118465084 4525901 complement(2449223..2450428) 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate; RNA polymerase sigma factor SigC 2450428 4525901 MAV_2426 Mycobacterium avium 104 RNA polymerase sigma factor SigC YP_881623.1 2449223 R 243243 CDS YP_881624.1 118464638 4528973 complement(2450464..2450712) 1 NC_008595.1 hypothetical protein 2450712 4528973 MAV_2428 Mycobacterium avium 104 hypothetical protein YP_881624.1 2450464 R 243243 CDS YP_881625.1 118462978 4527406 2450761..2452413 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2452413 4527406 MAV_2429 Mycobacterium avium 104 PPE family protein YP_881625.1 2450761 D 243243 CDS YP_881626.1 118463444 4529686 complement(2452417..2453907) 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466; match to protein family HMM TIGR01467; cobalamin biosynthesis protein cobIJ 2453907 4529686 MAV_2430 Mycobacterium avium 104 cobalamin biosynthesis protein cobIJ YP_881626.1 2452417 R 243243 CDS YP_881627.1 118466877 4526696 complement(2453904..2454425) 1 NC_008595.1 identified by match to protein family HMM PF02570; precorrin-8X methylmutase 2454425 4526696 MAV_2431 Mycobacterium avium 104 precorrin-8X methylmutase YP_881627.1 2453904 R 243243 CDS YP_881628.1 118464424 4530245 2455727..2456554 1 NC_008595.1 identified by match to protein family HMM PF00528; aliphatic sulfonates ABC transporter permease 2456554 4530245 MAV_2433 Mycobacterium avium 104 aliphatic sulfonates ABC transporter permease YP_881628.1 2455727 D 243243 CDS YP_881629.1 118463669 4525961 2456572..2457327 1 NC_008595.1 identified by match to protein family HMM PF00005; aliphatic sulfonates ABC transporter ATP-binding protein 2457327 4525961 MAV_2434 Mycobacterium avium 104 aliphatic sulfonates ABC transporter ATP-binding protein YP_881629.1 2456572 D 243243 CDS YP_881630.1 118462995 4530625 2457324..2458334 1 NC_008595.1 identified by match to protein family HMM TIGR01728; sulfonate binding protein 2458334 4530625 MAV_2435 Mycobacterium avium 104 sulfonate binding protein YP_881630.1 2457324 D 243243 CDS YP_881631.1 118462278 4529283 2458387..2459070 1 NC_008595.1 hypothetical protein 2459070 4529283 MAV_2436 Mycobacterium avium 104 hypothetical protein YP_881631.1 2458387 D 243243 CDS YP_881632.1 118467332 4526970 2459063..2462638 1 NC_008595.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 2462638 cobN 4526970 cobN Mycobacterium avium 104 cobaltochelatase subunit CobN YP_881632.1 2459063 D 243243 CDS YP_881633.1 118466448 4527121 complement(2462693..2463496) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 2463496 4527121 MAV_2438 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_881633.1 2462693 R 243243 CDS YP_881634.1 118465905 4528987 complement(2463500..2464108) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2464108 4528987 MAV_2439 Mycobacterium avium 104 TetR family transcriptional regulator YP_881634.1 2463500 R 243243 CDS YP_881635.1 118462337 4525682 complement(2465305..2466534) 1 NC_008595.1 hypothetical protein 2466534 4525682 MAV_2441 Mycobacterium avium 104 hypothetical protein YP_881635.1 2465305 R 243243 CDS YP_881636.1 118465209 4529846 2466761..2467141 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 2467141 4529846 MAV_2442 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_881636.1 2466761 D 243243 CDS YP_881637.1 118467084 4526384 complement(2467165..2467776) 1 NC_008595.1 identified by match to protein family HMM PF01738; dienelactone hydrolase 2467776 4526384 MAV_2443 Mycobacterium avium 104 dienelactone hydrolase YP_881637.1 2467165 R 243243 CDS YP_881638.1 118464471 4527064 2467939..2468454 1 NC_008595.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 2468454 fxsA 4527064 fxsA Mycobacterium avium 104 FxsA YP_881638.1 2467939 D 243243 CDS YP_881639.1 118463681 4528528 2468496..2470112 1 NC_008595.1 identified by match to protein family HMM PF07969; amidohydrolase 2470112 4528528 MAV_2445 Mycobacterium avium 104 amidohydrolase YP_881639.1 2468496 D 243243 CDS YP_881640.1 118466380 4526181 complement(2472796..2473092) 1 NC_008595.1 hypothetical protein 2473092 4526181 MAV_2447 Mycobacterium avium 104 hypothetical protein YP_881640.1 2472796 R 243243 CDS YP_881641.1 118466783 4529341 2473365..2473652 1 NC_008595.1 hypothetical protein 2473652 4529341 MAV_2448 Mycobacterium avium 104 hypothetical protein YP_881641.1 2473365 D 243243 CDS YP_881642.1 118462711 4530085 complement(2473915..2474040) 1 NC_008595.1 hypothetical protein 2474040 4530085 MAV_2449 Mycobacterium avium 104 hypothetical protein YP_881642.1 2473915 R 243243 CDS YP_881643.1 118463709 4530596 2474065..2486580 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801; erythronolide synthase, modules 3 and 4 2486580 4530596 MAV_2450 Mycobacterium avium 104 erythronolide synthase, modules 3 and 4 YP_881643.1 2474065 D 243243 CDS YP_881644.1 118462979 4527407 2486588..2489194 1 NC_008595.1 identified by match to protein family HMM PF00391; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; hypothetical protein 2489194 4527407 MAV_2451 Mycobacterium avium 104 hypothetical protein YP_881644.1 2486588 D 243243 CDS YP_881645.1 118463046 4528325 complement(2489214..2489561) 1 NC_008595.1 hypothetical protein 2489561 4528325 MAV_2452 Mycobacterium avium 104 hypothetical protein YP_881645.1 2489214 R 243243 CDS YP_881646.1 118464451 4525982 complement(2490357..2490485) 1 NC_008595.1 hypothetical protein 2490485 4525982 MAV_2454 Mycobacterium avium 104 hypothetical protein YP_881646.1 2490357 R 243243 CDS YP_881647.1 118463690 4528537 complement(2490503..2491297) 1 NC_008595.1 identified by match to protein family HMM PF07728; CbbQ/NirQ/NorQ/GpvN family protein 2491297 4528537 MAV_2455 Mycobacterium avium 104 CbbQ/NirQ/NorQ/GpvN family protein YP_881647.1 2490503 R 243243 CDS YP_881648.1 118465831 4525503 complement(2491320..2492858) 1 NC_008595.1 MorD protein 2492858 4525503 MAV_2456 Mycobacterium avium 104 MorD protein YP_881648.1 2491320 R 243243 CDS YP_881649.1 118465165 4529255 complement(2492859..2492963) 1 NC_008595.1 hypothetical protein 2492963 4529255 MAV_2457 Mycobacterium avium 104 hypothetical protein YP_881649.1 2492859 R 243243 CDS YP_881650.1 118466718 4530656 complement(2493010..2493717) 1 NC_008595.1 hypothetical protein 2493717 4530656 MAV_2458 Mycobacterium avium 104 hypothetical protein YP_881650.1 2493010 R 243243 CDS YP_881651.1 118462420 4525730 complement(2493894..2494487) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2494487 4525730 MAV_2459 Mycobacterium avium 104 TetR family transcriptional regulator YP_881651.1 2493894 R 243243 CDS YP_881652.1 118466675 4526625 2494706..2495494 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2495494 4526625 MAV_2460 Mycobacterium avium 104 short chain dehydrogenase YP_881652.1 2494706 D 243243 CDS YP_881653.1 118467242 4529799 2495519..2496601 1 NC_008595.1 hypothetical protein 2496601 4529799 MAV_2461 Mycobacterium avium 104 hypothetical protein YP_881653.1 2495519 D 243243 CDS YP_881654.1 118466739 4526340 2496710..2497318 1 NC_008595.1 hypothetical protein 2497318 4526340 MAV_2462 Mycobacterium avium 104 hypothetical protein YP_881654.1 2496710 D 243243 CDS YP_881655.1 118463650 4528552 complement(2497326..2497955) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2497955 4528552 MAV_2463 Mycobacterium avium 104 TetR family transcriptional regulator YP_881655.1 2497326 R 243243 CDS YP_881656.1 118462969 4526337 2498049..2499272 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 family protein 2499272 4526337 MAV_2464 Mycobacterium avium 104 cytochrome P450 family protein YP_881656.1 2498049 D 243243 CDS YP_881657.1 118464351 4529153 complement(2499370..2500035) 1 NC_008595.1 LppI protein 2500035 4529153 MAV_2465 Mycobacterium avium 104 LppI protein YP_881657.1 2499370 R 243243 CDS YP_881658.1 118465759 4530452 2500129..2501646 1 NC_008595.1 identified by match to protein family HMM PF00135; LppT protein 2501646 4530452 MAV_2466 Mycobacterium avium 104 LppT protein YP_881658.1 2500129 D 243243 CDS YP_881659.1 118466863 4529815 2501665..2503662 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 2503662 4529815 MAV_2467 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_881659.1 2501665 D 243243 CDS YP_881660.1 118464820 4527639 2503659..2504153 1 NC_008595.1 identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313; shikimate kinase 2504153 aroK 4527639 aroK Mycobacterium avium 104 shikimate kinase YP_881660.1 2503659 D 243243 CDS YP_881661.1 118465548 4525796 2504201..2504623 1 NC_008595.1 hypothetical protein 2504623 4525796 MAV_2469 Mycobacterium avium 104 hypothetical protein YP_881661.1 2504201 D 243243 CDS YP_881662.1 118466097 4527726 2504654..2505232 1 NC_008595.1 hypothetical protein 2505232 4527726 MAV_2470 Mycobacterium avium 104 hypothetical protein YP_881662.1 2504654 D 243243 CDS YP_881663.1 118466917 4529462 complement(2505237..2506268) 1 NC_008595.1 identified by match to protein family HMM PF07681; DoxX subfamily protein, putative 2506268 4529462 MAV_2471 Mycobacterium avium 104 DoxX subfamily protein, putative YP_881663.1 2505237 R 243243 CDS YP_881664.1 118463058 4528338 2506415..2506975 1 NC_008595.1 identified by match to protein family HMM PF00857; isochorismatase 2506975 4528338 MAV_2472 Mycobacterium avium 104 isochorismatase YP_881664.1 2506415 D 243243 CDS YP_881665.1 118463314 4529554 2506975..2507775 1 NC_008595.1 identified by match to protein family HMM PF02136; steroid delta-isomerase 2507775 4529554 MAV_2473 Mycobacterium avium 104 steroid delta-isomerase YP_881665.1 2506975 D 243243 CDS YP_881666.1 118463846 4529945 complement(2507789..2508139) 1 NC_008595.1 integral membrane protein 2508139 4529945 MAV_2474 Mycobacterium avium 104 integral membrane protein YP_881666.1 2507789 R 243243 CDS YP_881667.1 118464747 4527643 2508308..2509240 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase sigma factor 2509240 4527643 MAV_2475 Mycobacterium avium 104 RNA polymerase sigma factor YP_881667.1 2508308 D 243243 CDS YP_881668.1 118466482 4527612 2509306..2510634 1 NC_008595.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 2510634 4527612 MAV_2476 Mycobacterium avium 104 sugar ABC transporter substrate-binding protein YP_881668.1 2509306 D 243243 CDS YP_881669.1 118467218 4529599 2510631..2511575 1 NC_008595.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 2511575 4529599 MAV_2477 Mycobacterium avium 104 sugar ABC transporter permease YP_881669.1 2510631 D 243243 CDS YP_881670.1 118462451 4525624 2511562..2512404 1 NC_008595.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 2512404 4525624 MAV_2478 Mycobacterium avium 104 sugar ABC transporter permease YP_881670.1 2511562 D 243243 CDS YP_881671.1 118463169 4529871 2512401..2513492 1 NC_008595.1 identified by match to protein family HMM PF00005; glycerol-phosphate porter 2513492 4529871 MAV_2479 Mycobacterium avium 104 glycerol-phosphate porter YP_881671.1 2512401 D 243243 CDS YP_881672.1 118466341 4530481 2513498..2514454 1 NC_008595.1 identified by match to protein family HMM PF01734; phospholipase, patatin family protein 2514454 4530481 MAV_2480 Mycobacterium avium 104 phospholipase, patatin family protein YP_881672.1 2513498 D 243243 CDS YP_881673.1 118466725 4530663 complement(2514480..2514767) 1 NC_008595.1 hypothetical protein 2514767 4530663 MAV_2481 Mycobacterium avium 104 hypothetical protein YP_881673.1 2514480 R 243243 CDS YP_881674.1 118462595 4528499 2515001..2515834 1 NC_008595.1 hypothetical protein 2515834 4528499 MAV_2482 Mycobacterium avium 104 hypothetical protein YP_881674.1 2515001 D 243243 CDS YP_881675.1 118463050 4528329 2515916..2517526 1 NC_008595.1 identified by match to protein family HMM PF03239; iron permease FTR1 family protein 2517526 4528329 MAV_2483 Mycobacterium avium 104 iron permease FTR1 family protein YP_881675.1 2515916 D 243243 CDS YP_881676.1 118464792 4526716 2517564..2518739 1 NC_008595.1 identified by match to protein family HMM PF04302; hypothetical protein 2518739 4526716 MAV_2484 Mycobacterium avium 104 hypothetical protein YP_881676.1 2517564 D 243243 CDS YP_881677.1 118462539 4530540 2518742..2520058 1 NC_008595.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Tat-translocated enzyme 2520058 4530540 MAV_2485 Mycobacterium avium 104 Tat-translocated enzyme YP_881677.1 2518742 D 243243 CDS YP_881678.1 118463556 4526823 2520222..2520746 1 NC_008595.1 identified by match to protein family HMM PF02566; hypothetical protein 2520746 4526823 MAV_2486 Mycobacterium avium 104 hypothetical protein YP_881678.1 2520222 D 243243 CDS YP_881679.1 118465702 4530324 2520807..2521874 1 NC_008595.1 NtrC protein 2521874 4530324 MAV_2487 Mycobacterium avium 104 NtrC protein YP_881679.1 2520807 D 243243 CDS YP_881680.1 118462478 4528732 2521885..2522514 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase sigma factor, sigma-70 family protein 2522514 4528732 MAV_2488 Mycobacterium avium 104 RNA polymerase sigma factor, sigma-70 family protein YP_881680.1 2521885 D 243243 CDS YP_881681.1 118463421 4530058 2522511..2522780 1 NC_008595.1 hypothetical protein 2522780 4530058 MAV_2489 Mycobacterium avium 104 hypothetical protein YP_881681.1 2522511 D 243243 CDS YP_881682.1 118463840 4526059 2522777..2523721 1 NC_008595.1 identified by match to protein family HMM PF01226; formate/nitrite transporter superfamily protein 2523721 4526059 MAV_2490 Mycobacterium avium 104 formate/nitrite transporter superfamily protein YP_881682.1 2522777 D 243243 CDS YP_881683.1 118463409 4530046 2523789..2524097 1 NC_008595.1 hypothetical protein 2524097 4530046 MAV_2491 Mycobacterium avium 104 hypothetical protein YP_881683.1 2523789 D 243243 CDS YP_881684.1 118462715 4530089 complement(2524110..2525027) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2525027 4530089 MAV_2492 Mycobacterium avium 104 transposase YP_881684.1 2524110 R 243243 CDS YP_881685.1 118467255 4526090 complement(2525027..2525302) 1 NC_008595.1 transposase 2525302 4526090 MAV_2493 Mycobacterium avium 104 transposase YP_881685.1 2525027 R 243243 CDS YP_881686.1 118466078 4527345 2525286..2526023 1 NC_008595.1 identified by match to protein family HMM PF00582; universal stress protein family protein 2526023 4527345 MAV_2494 Mycobacterium avium 104 universal stress protein family protein YP_881686.1 2525286 D 243243 CDS YP_881687.1 118465651 4526176 complement(2526058..2527311) 1 NC_008595.1 hypothetical protein 2527311 4526176 MAV_2495 Mycobacterium avium 104 hypothetical protein YP_881687.1 2526058 R 243243 CDS YP_881688.1 118465115 4530467 2527455..2528426 1 NC_008595.1 identified by match to protein family HMM PF00248; aldo/keto reductase 2528426 4530467 MAV_2496 Mycobacterium avium 104 aldo/keto reductase YP_881688.1 2527455 D 243243 CDS YP_881689.1 118465647 4526172 complement(2528436..2529536) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; RmlD substrate binding domain-containing protein 2529536 4526172 MAV_2497 Mycobacterium avium 104 RmlD substrate binding domain-containing protein YP_881689.1 2528436 R 243243 CDS YP_881690.1 118463909 4525840 complement(2529544..2530062) 1 NC_008595.1 hypothetical protein 2530062 4525840 MAV_2498 Mycobacterium avium 104 hypothetical protein YP_881690.1 2529544 R 243243 CDS YP_881691.1 118464632 4528967 complement(2530125..2530931) 1 NC_008595.1 hypothetical protein 2530931 4528967 MAV_2499 Mycobacterium avium 104 hypothetical protein YP_881691.1 2530125 R 243243 CDS YP_881692.1 118462828 4528642 2531091..2532338 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase middle domain-containing protein 2532338 4528642 MAV_2500 Mycobacterium avium 104 acyl-CoA dehydrogenase middle domain-containing protein YP_881692.1 2531091 D 243243 CDS YP_881693.1 118467055 4526511 2532335..2533201 1 NC_008595.1 hypothetical protein 2533201 4526511 MAV_2501 Mycobacterium avium 104 hypothetical protein YP_881693.1 2532335 D 243243 CDS YP_881694.1 118463529 4526834 2533353..2534351 1 NC_008595.1 hypothetical protein 2534351 4526834 MAV_2502 Mycobacterium avium 104 hypothetical protein YP_881694.1 2533353 D 243243 CDS YP_881695.1 118463456 4529698 2534438..2534815 1 NC_008595.1 hypothetical protein 2534815 4529698 MAV_2503 Mycobacterium avium 104 hypothetical protein YP_881695.1 2534438 D 243243 CDS YP_881696.1 118465482 4527235 complement(2534994..2535422) 1 NC_008595.1 hypothetical protein 2535422 4527235 MAV_2504 Mycobacterium avium 104 hypothetical protein YP_881696.1 2534994 R 243243 CDS YP_881697.1 118464897 4529626 2535704..2536705 1 NC_008595.1 hypothetical protein 2536705 4529626 MAV_2505 Mycobacterium avium 104 hypothetical protein YP_881697.1 2535704 D 243243 CDS YP_881698.1 118466893 4528407 2536772..2537653 1 NC_008595.1 identified by match to protein family HMM PF00582; universal stress protein family protein 2537653 4528407 MAV_2506 Mycobacterium avium 104 universal stress protein family protein YP_881698.1 2536772 D 243243 CDS YP_881699.1 118466349 4530489 2537812..2538696 1 NC_008595.1 identified by match to protein family HMM PF00582; universal stress protein family protein 2538696 4530489 MAV_2507 Mycobacterium avium 104 universal stress protein family protein YP_881699.1 2537812 D 243243 CDS YP_881700.1 118465563 4526749 2538852..2540264 1 NC_008595.1 identified by match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; PAS domain-containing protein 2540264 4526749 MAV_2508 Mycobacterium avium 104 PAS domain-containing protein YP_881700.1 2538852 D 243243 CDS YP_881701.1 118466432 4530176 2540371..2541153 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 2541153 4530176 MAV_2509 Mycobacterium avium 104 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase YP_881701.1 2540371 D 243243 CDS YP_881702.1 118464643 4528978 complement(2541228..2544128) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL4 protein 2544128 4528978 MAV_2510 Mycobacterium avium 104 MmpL4 protein YP_881702.1 2541228 R 243243 CDS YP_881703.1 118462696 4526676 complement(2544125..2544559) 1 NC_008595.1 identified by match to protein family HMM PF05423; MmpS5 protein 2544559 4526676 MAV_2511 Mycobacterium avium 104 MmpS5 protein YP_881703.1 2544125 R 243243 CDS YP_881704.1 118464002 4529264 complement(2544858..2545466) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2545466 4529264 MAV_2512 Mycobacterium avium 104 TetR family transcriptional regulator YP_881704.1 2544858 R 243243 CDS YP_881705.1 118464243 4527427 complement(2545668..2546594) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 2546594 4527427 MAV_2513 Mycobacterium avium 104 alpha/beta hydrolase YP_881705.1 2545668 R 243243 CDS YP_881706.1 118464808 4527627 complement(2546696..2548282) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2548282 4527627 MAV_2514 Mycobacterium avium 104 PPE family protein YP_881706.1 2546696 R 243243 CDS YP_881707.1 118465493 4526789 complement(2548507..2549538) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2549538 4526789 MAV_2515 Mycobacterium avium 104 amidohydrolase YP_881707.1 2548507 R 243243 CDS YP_881708.1 118466213 4528892 complement(2549555..2550553) 1 NC_008595.1 identified by match to protein family HMM PF00903; extradiol ring cleaving catechol dioxygenase 2550553 4528892 MAV_2516 Mycobacterium avium 104 extradiol ring cleaving catechol dioxygenase YP_881708.1 2549555 R 243243 CDS YP_881709.1 118466920 4529466 complement(2550550..2551422) 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 2551422 4529466 MAV_2517 Mycobacterium avium 104 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_881709.1 2550550 R 243243 CDS YP_881710.1 118464517 4529437 complement(2551419..2552483) 1 NC_008595.1 identified by match to protein family HMM PF01494; monooxygenase, FAD-binding 2552483 4529437 MAV_2518 Mycobacterium avium 104 monooxygenase, FAD-binding YP_881710.1 2551419 R 243243 CDS YP_881711.1 118466405 4526248 complement(2552571..2553845) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2553845 4526248 MAV_2519 Mycobacterium avium 104 transposase, Mutator family protein YP_881711.1 2552571 R 243243 CDS YP_881712.1 118465020 4530069 complement(2553898..2554338) 1 NC_008595.1 hypothetical protein 2554338 4530069 MAV_2520 Mycobacterium avium 104 hypothetical protein YP_881712.1 2553898 R 243243 CDS YP_881713.1 118462384 4525927 2554591..2556120 1 NC_008595.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722; methylmalonate-semialdehyde dehydrogenase 2556120 mmsA 4525927 mmsA Mycobacterium avium 104 methylmalonate-semialdehyde dehydrogenase YP_881713.1 2554591 D 243243 CDS YP_881714.1 118465475 4527228 2556196..2556360 1 NC_008595.1 hypothetical protein 2556360 4527228 MAV_2522 Mycobacterium avium 104 hypothetical protein YP_881714.1 2556196 D 243243 CDS YP_881715.1 118463096 4528919 2556899..2557516 1 NC_008595.1 hypothetical protein 2557516 4528919 MAV_2523 Mycobacterium avium 104 hypothetical protein YP_881715.1 2556899 D 243243 CDS YP_881716.1 118463515 4527695 complement(2557598..2557879) 1 NC_008595.1 hypothetical protein 2557879 4527695 MAV_2524 Mycobacterium avium 104 hypothetical protein YP_881716.1 2557598 R 243243 CDS YP_881717.1 118466170 4526201 complement(2558048..2558182) 1 NC_008595.1 hypothetical protein 2558182 4526201 MAV_2525 Mycobacterium avium 104 hypothetical protein YP_881717.1 2558048 R 243243 CDS YP_881718.1 118464417 4530238 2558458..2559762 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2559762 4530238 MAV_2526 Mycobacterium avium 104 transposase, Mutator family protein YP_881718.1 2558458 D 243243 CDS YP_881719.1 118466915 4529460 complement(2559817..2560323) 1 NC_008595.1 identified by match to protein family HMM PF00440; repressor protein 2560323 4529460 MAV_2527 Mycobacterium avium 104 repressor protein YP_881719.1 2559817 R 243243 CDS YP_881720.1 118465880 4527522 2560853..2562433 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2562433 4527522 MAV_2528 Mycobacterium avium 104 transposase YP_881720.1 2560853 D 243243 CDS YP_881721.1 118466698 4529705 2562430..2563224 1 NC_008595.1 identified by match to protein family HMM PF01695; helper protein 2563224 4529705 MAV_2529 Mycobacterium avium 104 helper protein YP_881721.1 2562430 D 243243 CDS YP_881722.1 118467231 4529788 2564369..2565154 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB1 protein 2565154 4529788 MAV_2530 Mycobacterium avium 104 TrnB1 protein YP_881722.1 2564369 D 243243 CDS YP_881723.1 118466059 4530029 2565151..2566035 1 NC_008595.1 identified by match to protein family HMM PF02405; TrnB2 protein 2566035 4530029 MAV_2531 Mycobacterium avium 104 TrnB2 protein YP_881723.1 2565151 D 243243 CDS YP_881724.1 118465483 4527236 2566171..2567511 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2567511 4527236 MAV_2532 Mycobacterium avium 104 virulence factor Mce YP_881724.1 2566171 D 243243 CDS YP_881725.1 118464539 4530409 2567550..2568578 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2568578 4530409 MAV_2533 Mycobacterium avium 104 virulence factor Mce YP_881725.1 2567550 D 243243 CDS YP_881726.1 118463925 4528105 2568575..2569900 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2569900 4528105 MAV_2534 Mycobacterium avium 104 virulence factor Mce YP_881726.1 2568575 D 243243 CDS YP_881727.1 118466668 4526618 2569924..2571243 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2571243 4526618 MAV_2535 Mycobacterium avium 104 virulence factor Mce YP_881727.1 2569924 D 243243 CDS YP_881728.1 118463194 4527717 2571240..2572400 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2572400 4527717 MAV_2536 Mycobacterium avium 104 virulence factor Mce YP_881728.1 2571240 D 243243 CDS YP_881729.1 118464917 4528557 2572402..2573877 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 2573877 4528557 MAV_2537 Mycobacterium avium 104 virulence factor Mce YP_881729.1 2572402 D 243243 CDS YP_881730.1 118467240 4529797 2573994..2574572 1 NC_008595.1 hypothetical protein 2574572 4529797 MAV_2538 Mycobacterium avium 104 hypothetical protein YP_881730.1 2573994 D 243243 CDS YP_881731.1 118462794 4525763 2574737..2575336 1 NC_008595.1 hypothetical protein 2575336 4525763 MAV_2539 Mycobacterium avium 104 hypothetical protein YP_881731.1 2574737 D 243243 CDS YP_881732.1 118464800 4526724 2575607..2576461 1 NC_008595.1 identified by match to protein family HMM PF02551; acyl-CoA thioesterase 2576461 4526724 MAV_2540 Mycobacterium avium 104 acyl-CoA thioesterase YP_881732.1 2575607 D 243243 CDS YP_881733.1 118466303 4528345 complement(2576492..2577694) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 2577694 4528345 MAV_2541 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881733.1 2576492 R 243243 CDS YP_881734.1 118462970 4527398 complement(2577759..2578541) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 2578541 4527398 MAV_2542 Mycobacterium avium 104 GntR family transcriptional regulator YP_881734.1 2577759 R 243243 CDS YP_881735.1 118464321 4529826 complement(2578617..2579612) 1 NC_008595.1 5,10-methylenetetrahydromethanopterin reductase 2579612 4529826 MAV_2543 Mycobacterium avium 104 5,10-methylenetetrahydromethanopterin reductase YP_881735.1 2578617 R 243243 CDS YP_881736.1 118465965 4528184 2579790..2580803 1 NC_008595.1 identified by match to protein family HMM PF00355; iron-sulfur cluster-binding protein, Rieske family protein 2580803 4528184 MAV_2544 Mycobacterium avium 104 iron-sulfur cluster-binding protein, Rieske family protein YP_881736.1 2579790 D 243243 CDS YP_881737.1 118462261 4526404 2580793..2581404 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2581404 4526404 MAV_2546 Mycobacterium avium 104 TetR family transcriptional regulator YP_881737.1 2580793 D 243243 CDS YP_881738.1 118463144 4527782 complement(2581388..2581633) 1 NC_008595.1 hypothetical protein 2581633 4527782 MAV_2545 Mycobacterium avium 104 hypothetical protein YP_881738.1 2581388 R 243243 CDS YP_881739.1 118467099 4526360 2582115..2583641 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 2583641 4526360 MAV_2547 Mycobacterium avium 104 acyl-CoA synthetase YP_881739.1 2582115 D 243243 CDS YP_881740.1 118466259 4526878 complement(2583646..2584803) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 143 2584803 4526878 MAV_2548 Mycobacterium avium 104 cytochrome P450 143 YP_881740.1 2583646 R 243243 CDS YP_881741.1 118465981 4526123 complement(2584819..2585616) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 2585616 4526123 MAV_2549 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881741.1 2584819 R 243243 CDS YP_881742.1 118465446 4527315 complement(2585629..2586459) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 2586459 4527315 MAV_2550 Mycobacterium avium 104 carveol dehydrogenase YP_881742.1 2585629 R 243243 CDS YP_881743.1 118463629 4527333 2586623..2587450 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2587450 4527333 MAV_2551 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881743.1 2586623 D 243243 CDS YP_881744.1 118466510 4525593 complement(2587497..2588276) 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-hydroxyacyl-CoA dehydrogenase type-2 2588276 4525593 MAV_2552 Mycobacterium avium 104 3-hydroxyacyl-CoA dehydrogenase type-2 YP_881744.1 2587497 R 243243 CDS YP_881745.1 118463787 4530138 complement(2588273..2589382) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2589382 4530138 MAV_2553 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881745.1 2588273 R 243243 CDS YP_881746.1 118464413 4530807 complement(2589379..2590530) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase, central region 2590530 4530807 MAV_2554 Mycobacterium avium 104 acyl-CoA dehydrogenase, central region YP_881746.1 2589379 R 243243 CDS YP_881747.1 118462398 4525942 complement(2590540..2591367) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 2591367 4525942 MAV_2555 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881747.1 2590540 R 243243 CDS YP_881748.1 118462944 4530229 2591506..2592726 1 NC_008595.1 hypothetical protein 2592726 4530229 MAV_2556 Mycobacterium avium 104 hypothetical protein YP_881748.1 2591506 D 243243 CDS YP_881749.1 118466111 4529744 2592723..2593883 1 NC_008595.1 identified by match to protein family HMM PF02803; thiolase 2593883 4529744 MAV_2557 Mycobacterium avium 104 thiolase YP_881749.1 2592723 D 243243 CDS YP_881750.1 118467264 4526099 2593896..2594705 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 2594705 4526099 MAV_2558 Mycobacterium avium 104 enoyl-CoA hydratase YP_881750.1 2593896 D 243243 CDS YP_881751.1 118466646 4528084 complement(2594731..2595555) 1 NC_008595.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 2595555 4528084 MAV_2559 Mycobacterium avium 104 hypothetical protein YP_881751.1 2594731 R 243243 CDS YP_881752.1 118467208 4529589 complement(2595552..2596292) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 2596292 4529589 MAV_2560 Mycobacterium avium 104 GntR family transcriptional regulator YP_881752.1 2595552 R 243243 CDS YP_881753.1 118465257 4528475 complement(2596402..2597544) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; long-chain specific acyl-CoA dehydrogenase 2597544 4528475 MAV_2561 Mycobacterium avium 104 long-chain specific acyl-CoA dehydrogenase YP_881753.1 2596402 R 243243 CDS YP_881754.1 118467019 4529489 complement(2597555..2598574) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2598574 4529489 MAV_2562 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881754.1 2597555 R 243243 CDS YP_881755.1 118465060 4527036 complement(2598571..2599776) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 2599776 4527036 MAV_2563 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881755.1 2598571 R 243243 CDS YP_881756.1 118464157 4526467 2599892..2601385 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase (NAD) family protein 2601385 4526467 MAV_2564 Mycobacterium avium 104 aldehyde dehydrogenase (NAD) family protein YP_881756.1 2599892 D 243243 CDS YP_881757.1 118464664 4528261 2601382..2602593 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 2602593 4528261 MAV_2565 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881757.1 2601382 D 243243 CDS YP_881758.1 118464096 4525857 2602593..2603552 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 2603552 4525857 MAV_2566 Mycobacterium avium 104 glyoxalase YP_881758.1 2602593 D 243243 CDS YP_881759.1 118463188 4527711 2603568..2604344 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 2604344 4527711 MAV_2567 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_881759.1 2603568 D 243243 CDS YP_881760.1 118466365 4529927 complement(2605283..2606473) 1 NC_008595.1 acetyl-CoA hydrolase/transferase, putative 2606473 4529927 MAV_2569 Mycobacterium avium 104 acetyl-CoA hydrolase/transferase, putative YP_881760.1 2605283 R 243243 CDS YP_881761.1 118464342 4529144 complement(2606482..2608800) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2608800 4529144 MAV_2570 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881761.1 2606482 R 243243 CDS YP_881762.1 118464091 4525852 complement(2608797..2610287) 1 NC_008595.1 identified by match to protein family HMM PF00501; cyclohex-1-ene-1-carboxylate:CoA ligase 2610287 4525852 MAV_2571 Mycobacterium avium 104 cyclohex-1-ene-1-carboxylate:CoA ligase YP_881762.1 2608797 R 243243 CDS YP_881763.1 118463712 4528062 complement(2610313..2611533) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 142 2611533 4528062 MAV_2572 Mycobacterium avium 104 cytochrome P450 142 YP_881763.1 2610313 R 243243 CDS YP_881764.1 118464050 4529022 complement(2611560..2612714) 1 NC_008595.1 lipid-transfer protein 2612714 4529022 MAV_2573 Mycobacterium avium 104 lipid-transfer protein YP_881764.1 2611560 R 243243 CDS YP_881765.1 118465694 4530316 2612900..2614387 1 NC_008595.1 identified by match to protein family HMM PF00501; feruloyl-CoA synthetase 2614387 4530316 MAV_2574 Mycobacterium avium 104 feruloyl-CoA synthetase YP_881765.1 2612900 D 243243 CDS YP_881766.1 118465075 4525892 2614469..2614723 1 NC_008595.1 hypothetical protein 2614723 4525892 MAV_2575 Mycobacterium avium 104 hypothetical protein YP_881766.1 2614469 D 243243 CDS YP_881767.1 118466717 4529724 complement(2614791..2615732) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase 2615732 4529724 MAV_2576 Mycobacterium avium 104 methyltransferase YP_881767.1 2614791 R 243243 CDS YP_881768.1 118466194 4530184 complement(2615831..2617060) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2617060 4530184 MAV_2577 Mycobacterium avium 104 amidohydrolase YP_881768.1 2615831 R 243243 CDS YP_881769.1 118462870 4527098 2617208..2617828 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2617828 4527098 MAV_2578 Mycobacterium avium 104 TetR family transcriptional regulator YP_881769.1 2617208 D 243243 CDS YP_881770.1 118464699 4527888 2617825..2618265 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 2618265 4527888 MAV_2579 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_881770.1 2617825 D 243243 CDS YP_881771.1 118464365 4530508 2618291..2618617 1 NC_008595.1 hypothetical protein 2618617 4530508 MAV_2580 Mycobacterium avium 104 hypothetical protein YP_881771.1 2618291 D 243243 CDS YP_881772.1 118466666 4526616 2618654..2618800 1 NC_008595.1 hypothetical protein 2618800 4526616 MAV_2581 Mycobacterium avium 104 hypothetical protein YP_881772.1 2618654 D 243243 CDS YP_881773.1 118466823 4527388 complement(2618806..2619828) 1 NC_008595.1 hypothetical protein 2619828 4527388 MAV_2582 Mycobacterium avium 104 hypothetical protein YP_881773.1 2618806 R 243243 CDS YP_881774.1 118466597 4529363 complement(2619839..2620273) 1 NC_008595.1 hypothetical protein 2620273 4529363 MAV_2583 Mycobacterium avium 104 hypothetical protein YP_881774.1 2619839 R 243243 CDS YP_881775.1 118464809 4527628 complement(2620275..2621462) 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; beta-ketoadipyl CoA thiolase 2621462 4527628 MAV_2584 Mycobacterium avium 104 beta-ketoadipyl CoA thiolase YP_881775.1 2620275 R 243243 CDS YP_881776.1 118465741 4525704 2621591..2622031 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC domain-containing protein 2622031 4525704 MAV_2585 Mycobacterium avium 104 MaoC domain-containing protein YP_881776.1 2621591 D 243243 CDS YP_881777.1 118463570 4530725 2622028..2623221 1 NC_008595.1 DitF protein 2623221 4530725 MAV_2586 Mycobacterium avium 104 DitF protein YP_881777.1 2622028 D 243243 CDS YP_881778.1 118463987 4530346 2623225..2624787 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 2624787 4530346 MAV_2587 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881778.1 2623225 D 243243 CDS YP_881779.1 118462446 4525619 complement(2624798..2626096) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2626096 4525619 MAV_2588 Mycobacterium avium 104 TetR family transcriptional regulator YP_881779.1 2624798 R 243243 CDS YP_881780.1 118467337 4526975 complement(2626126..2626440) 1 NC_008595.1 hypothetical protein 2626440 4526975 MAV_2589 Mycobacterium avium 104 hypothetical protein YP_881780.1 2626126 R 243243 CDS YP_881781.1 118463458 4529700 2626625..2627761 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2627761 4529700 MAV_2591 Mycobacterium avium 104 amidohydrolase YP_881781.1 2626625 D 243243 CDS YP_881782.1 118466132 4527898 complement(2627758..2628912) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2628912 4527898 MAV_2590 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881782.1 2627758 R 243243 CDS YP_881783.1 118465392 4529684 2629133..2629327 1 NC_008595.1 hypothetical protein 2629327 4529684 MAV_2592 Mycobacterium avium 104 hypothetical protein YP_881783.1 2629133 D 243243 CDS YP_881784.1 118467120 4526147 2629404..2631698 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2631698 4526147 MAV_2593 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881784.1 2629404 D 243243 CDS YP_881785.1 118466408 4526251 2631743..2632933 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 2632933 4526251 MAV_2594 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881785.1 2631743 D 243243 CDS YP_881786.1 118463135 4529660 complement(2632937..2633944) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2633944 4529660 MAV_2595 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881786.1 2632937 R 243243 CDS YP_881787.1 118462432 4528295 2634038..2635555 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 2635555 4528295 MAV_2596 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881787.1 2634038 D 243243 CDS YP_881788.1 118464284 4529572 2635593..2636402 1 NC_008595.1 identified by match to protein family HMM PF00378; carnitinyl-CoA dehydratase 2636402 4529572 MAV_2597 Mycobacterium avium 104 carnitinyl-CoA dehydratase YP_881788.1 2635593 D 243243 CDS YP_881789.1 118463578 4529763 2636404..2637255 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 2637255 4529763 MAV_2598 Mycobacterium avium 104 carveol dehydrogenase YP_881789.1 2636404 D 243243 CDS YP_881790.1 118464046 4529018 2637264..2638589 1 NC_008595.1 hypothetical protein 2638589 4529018 MAV_2599 Mycobacterium avium 104 hypothetical protein YP_881790.1 2637264 D 243243 CDS YP_881791.1 118465554 4525803 2638599..2639741 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2639741 4525803 MAV_2600 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881791.1 2638599 D 243243 CDS YP_881792.1 118465245 4528463 2639752..2640507 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2640507 4528463 MAV_2601 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881792.1 2639752 D 243243 CDS YP_881793.1 118467316 4530309 2640554..2641351 1 NC_008595.1 identified by match to protein family HMM PF00561; hydrolase 2641351 4530309 MAV_2602 Mycobacterium avium 104 hydrolase YP_881793.1 2640554 D 243243 CDS YP_881794.1 118462605 4528509 complement(2641513..2642322) 1 NC_008595.1 hypothetical protein 2642322 4528509 MAV_2603 Mycobacterium avium 104 hypothetical protein YP_881794.1 2641513 R 243243 CDS YP_881795.1 118463292 4525986 complement(2642360..2643109) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 2643109 4525986 MAV_2604 Mycobacterium avium 104 alpha/beta hydrolase YP_881795.1 2642360 R 243243 CDS YP_881796.1 118463962 4527208 complement(2643121..2644053) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2644053 4527208 MAV_2605 Mycobacterium avium 104 hypothetical protein YP_881796.1 2643121 R 243243 CDS YP_881797.1 118464496 4525539 complement(2644065..2645183) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2645183 4525539 MAV_2606 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881797.1 2644065 R 243243 CDS YP_881798.1 118465692 4525751 complement(2645228..2645818) 1 NC_008595.1 identified by match to protein family HMM PF01613; flavin reductase-like domain-containing protein 2645818 4525751 MAV_2607 Mycobacterium avium 104 flavin reductase-like domain-containing protein YP_881798.1 2645228 R 243243 CDS YP_881799.1 118466243 4526589 complement(2645838..2647328) 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 2647328 4526589 MAV_2608 Mycobacterium avium 104 aldehyde dehydrogenase YP_881799.1 2645838 R 243243 CDS YP_881800.1 118463664 4525956 complement(2647339..2648121) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2648121 4525956 MAV_2609 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881800.1 2647339 R 243243 CDS YP_881801.1 118463016 4526309 complement(2648118..2649725) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 2649725 4526309 MAV_2610 Mycobacterium avium 104 acyl-CoA synthase YP_881801.1 2648118 R 243243 CDS YP_881802.1 118465047 4525826 complement(2649740..2650255) 1 NC_008595.1 identified by match to protein family HMM PF00866; dioxygenase small subunit 2650255 4525826 MAV_2611 Mycobacterium avium 104 dioxygenase small subunit YP_881802.1 2649740 R 243243 CDS YP_881803.1 118464430 4530251 complement(2650252..2651547) 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM PF00848; dioxygenase large subunit 2651547 4530251 MAV_2612 Mycobacterium avium 104 dioxygenase large subunit YP_881803.1 2650252 R 243243 CDS YP_881804.1 118466621 4526859 complement(2651544..2651984) 1 NC_008595.1 hypothetical protein 2651984 4526859 MAV_2613 Mycobacterium avium 104 hypothetical protein YP_881804.1 2651544 R 243243 CDS YP_881805.1 118462917 4526006 complement(2651981..2653132) 1 NC_008595.1 thiolase 2653132 4526006 MAV_2614 Mycobacterium avium 104 thiolase YP_881805.1 2651981 R 243243 CDS YP_881806.1 118463137 4529662 complement(2653129..2653374) 1 NC_008595.1 hypothetical protein 2653374 4529662 MAV_2615 Mycobacterium avium 104 hypothetical protein YP_881806.1 2653129 R 243243 CDS YP_881807.1 118464315 4526646 2653569..2654495 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase 2654495 4526646 MAV_2616 Mycobacterium avium 104 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase YP_881807.1 2653569 D 243243 CDS YP_881808.1 118465970 4528189 2654492..2655313 1 NC_008595.1 identified by match to protein family HMM PF01689; match to protein family HMM TIGR02312; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 2655313 hpaH 4528189 hpaH Mycobacterium avium 104 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_881808.1 2654492 D 243243 CDS YP_881809.1 118463147 4527785 2655310..2656074 1 NC_008595.1 identified by match to protein family HMM PF03328; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 2656074 4527785 MAV_2618 Mycobacterium avium 104 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_881809.1 2655310 D 243243 CDS YP_881810.1 118462250 4526936 2656120..2657292 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase domain-containing protein 2657292 4526936 MAV_2619 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_881810.1 2656120 D 243243 CDS YP_881811.1 118467093 4526393 2657305..2658327 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2658327 4526393 MAV_2620 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881811.1 2657305 D 243243 CDS YP_881812.1 118466253 4526872 2658324..2659484 1 NC_008595.1 thiolase 2659484 4526872 MAV_2621 Mycobacterium avium 104 thiolase YP_881812.1 2658324 D 243243 CDS YP_881813.1 118465984 4526126 2659485..2660984 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 2660984 4526126 MAV_2622 Mycobacterium avium 104 acyl-CoA synthase YP_881813.1 2659485 D 243243 CDS YP_881814.1 118466143 4527909 2661019..2661813 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 2661813 4527909 MAV_2623 Mycobacterium avium 104 carveol dehydrogenase YP_881814.1 2661019 D 243243 CDS YP_881815.1 118464550 4530420 complement(2661823..2662359) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 2662359 4530420 MAV_2624 Mycobacterium avium 104 thioesterase YP_881815.1 2661823 R 243243 CDS YP_881816.1 118462692 4526672 2662524..2664944 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 2664944 4526672 MAV_2625 Mycobacterium avium 104 caib/baif family protein YP_881816.1 2662524 D 243243 CDS YP_881817.1 118467331 4526969 complement(2664949..2665632) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2665632 4526969 MAV_2626 Mycobacterium avium 104 TetR family transcriptional regulator YP_881817.1 2664949 R 243243 CDS YP_881818.1 118463196 4527719 2665775..2666005 1 NC_008595.1 hypothetical protein 2666005 4527719 MAV_2628 Mycobacterium avium 104 hypothetical protein YP_881818.1 2665775 D 243243 CDS YP_881819.1 118464879 4529608 complement(2665995..2667269) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2667269 4529608 MAV_2627 Mycobacterium avium 104 transposase, Mutator family protein YP_881819.1 2665995 R 243243 CDS YP_881820.1 118463307 4526002 2667375..2668328 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2668328 4526002 MAV_2629 Mycobacterium avium 104 amidohydrolase YP_881820.1 2667375 D 243243 CDS YP_881821.1 118466546 4527014 2668369..2669532 1 NC_008595.1 thiolase 2669532 4527014 MAV_2630 Mycobacterium avium 104 thiolase YP_881821.1 2668369 D 243243 CDS YP_881822.1 118463896 4530573 2669529..2669984 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 2669984 4530573 MAV_2631 Mycobacterium avium 104 hypothetical protein YP_881822.1 2669529 D 243243 CDS YP_881823.1 118464631 4528966 complement(2670479..2671048) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcription regulator 2671048 4528966 MAV_2632 Mycobacterium avium 104 transcription regulator YP_881823.1 2670479 R 243243 CDS YP_881824.1 118465729 4527464 2671324..2672403 1 NC_008595.1 hypothetical protein 2672403 4527464 MAV_2633 Mycobacterium avium 104 hypothetical protein YP_881824.1 2671324 D 243243 CDS YP_881825.1 118466479 4527609 2672701..2673873 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome p450 2673873 4527609 MAV_2634 Mycobacterium avium 104 cytochrome p450 YP_881825.1 2672701 D 243243 CDS YP_881826.1 118465923 4528482 2673899..2674738 1 NC_008595.1 identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase 2674738 4528482 MAV_2635 Mycobacterium avium 104 3-hydroxyisobutyrate dehydrogenase YP_881826.1 2673899 D 243243 CDS YP_881827.1 118465384 4529676 2674807..2675556 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 2675556 4529676 MAV_2636 Mycobacterium avium 104 carveol dehydrogenase YP_881827.1 2674807 D 243243 CDS YP_881828.1 118462795 4525764 2675573..2677174 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 2677174 4525764 MAV_2638 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_881828.1 2675573 D 243243 CDS YP_881829.1 118464300 4526630 complement(2677171..2677707) 1 NC_008595.1 hypothetical protein 2677707 4526630 MAV_2637 Mycobacterium avium 104 hypothetical protein YP_881829.1 2677171 R 243243 CDS YP_881830.1 118463543 4526810 complement(2677758..2678681) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2678681 4526810 MAV_2639 Mycobacterium avium 104 short chain dehydrogenase YP_881830.1 2677758 R 243243 CDS YP_881831.1 118462946 4530231 complement(2678678..2679112) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 2679112 4530231 MAV_2640 Mycobacterium avium 104 hypothetical protein YP_881831.1 2678678 R 243243 CDS YP_881832.1 118462438 4528301 complement(2679106..2679909) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl CoA hydratase 2679909 4528301 MAV_2641 Mycobacterium avium 104 enoyl CoA hydratase YP_881832.1 2679106 R 243243 CDS YP_881833.1 118463528 4526833 complement(2679906..2681180) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 2681180 4526833 MAV_2642 Mycobacterium avium 104 cytochrome P450 YP_881833.1 2679906 R 243243 CDS YP_881834.1 118465584 4527131 2681324..2682406 1 NC_008595.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD-binding Rossmann fold protein 2682406 4527131 MAV_2643 Mycobacterium avium 104 oxidoreductase, NAD-binding Rossmann fold protein YP_881834.1 2681324 D 243243 CDS YP_881835.1 118462518 4527661 2682591..2683094 1 NC_008595.1 hypothetical protein 2683094 4527661 MAV_2644 Mycobacterium avium 104 hypothetical protein YP_881835.1 2682591 D 243243 CDS YP_881836.1 118463157 4527795 complement(2683125..2683847) 1 NC_008595.1 carveol dehydrogenase 2683847 4527795 MAV_2645 Mycobacterium avium 104 carveol dehydrogenase YP_881836.1 2683125 R 243243 CDS YP_881837.1 118465019 4530068 complement(2684122..2685255) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase B 2685255 4530068 MAV_2646 Mycobacterium avium 104 alcohol dehydrogenase B YP_881837.1 2684122 R 243243 CDS YP_881838.1 118466843 4526952 complement(2685272..2686735) 1 NC_008595.1 identified by match to protein family HMM PF00171; betaine-aldehyde dehydrogenase 2686735 4526952 MAV_2647 Mycobacterium avium 104 betaine-aldehyde dehydrogenase YP_881838.1 2685272 R 243243 CDS YP_881839.1 118463734 4528142 2686814..2687248 1 NC_008595.1 hypothetical protein 2687248 4528142 MAV_2648 Mycobacterium avium 104 hypothetical protein YP_881839.1 2686814 D 243243 CDS YP_881840.1 118465502 4526799 2687245..2687730 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC like domain-containing protein 2687730 4526799 MAV_2649 Mycobacterium avium 104 MaoC like domain-containing protein YP_881840.1 2687245 D 243243 CDS YP_881841.1 118465423 4529972 2687743..2689083 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 2689083 4529972 MAV_2650 Mycobacterium avium 104 transcriptional regulator YP_881841.1 2687743 D 243243 CDS YP_881842.1 118464720 4529407 complement(2689097..2690254) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 2690254 4529407 MAV_2651 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881842.1 2689097 R 243243 CDS YP_881843.1 118463815 4526071 2690599..2691579 1 NC_008595.1 identified by match to protein family HMM PF02515; fatty acid-CoA racemase 2691579 4526071 MAV_2653 Mycobacterium avium 104 fatty acid-CoA racemase YP_881843.1 2690599 D 243243 CDS YP_881844.1 118464210 4526890 complement(2691571..2692293) 1 NC_008595.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 2692293 mhpB 4526890 mhpB Mycobacterium avium 104 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_881844.1 2691571 R 243243 CDS YP_881845.1 118465660 4526732 complement(2692489..2692659) 1 NC_008595.1 hypothetical protein 2692659 4526732 MAV_2654 Mycobacterium avium 104 hypothetical protein YP_881845.1 2692489 R 243243 CDS YP_881846.1 118464326 4529831 complement(2692673..2693515) 1 NC_008595.1 hypothetical protein 2693515 4529831 MAV_2655 Mycobacterium avium 104 hypothetical protein YP_881846.1 2692673 R 243243 CDS YP_881847.1 118462326 4529644 2693820..2694860 1 NC_008595.1 hypothetical protein 2694860 4529644 MAV_2656 Mycobacterium avium 104 hypothetical protein YP_881847.1 2693820 D 243243 CDS YP_881848.1 118463009 4526302 complement(2694867..2695457) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 2695457 4526302 MAV_2657 Mycobacterium avium 104 transcriptional regulator YP_881848.1 2694867 R 243243 CDS YP_881849.1 118463806 4526061 2695625..2696815 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 2696815 4526061 MAV_2658 Mycobacterium avium 104 cytochrome P450 YP_881849.1 2695625 D 243243 CDS YP_881850.1 118464333 4529838 complement(2696839..2697759) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2697759 4529838 MAV_2659 Mycobacterium avium 104 hypothetical protein YP_881850.1 2696839 R 243243 CDS YP_881851.1 118465952 4527948 2698001..2698366 1 NC_008595.1 hypothetical protein 2698366 4527948 MAV_2660 Mycobacterium avium 104 hypothetical protein YP_881851.1 2698001 D 243243 CDS YP_881852.1 118462341 4525686 2698366..2698974 1 NC_008595.1 identified by match to protein family HMM PF00881; nitroreductase 2698974 4525686 MAV_2661 Mycobacterium avium 104 nitroreductase YP_881852.1 2698366 D 243243 CDS YP_881853.1 118463151 4527789 2698994..2701144 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 2701144 4527789 MAV_2662 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881853.1 2698994 D 243243 CDS YP_881854.1 118466560 4529109 2701158..2702294 1 NC_008595.1 lipid-transfer protein 2702294 4529109 MAV_2663 Mycobacterium avium 104 lipid-transfer protein YP_881854.1 2701158 D 243243 CDS YP_881855.1 118466200 4530190 2702378..2702701 1 NC_008595.1 hypothetical protein 2702701 4530190 MAV_2664 Mycobacterium avium 104 hypothetical protein YP_881855.1 2702378 D 243243 CDS YP_881856.1 118465147 4529237 2702718..2703539 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-oxoacyl-[acyl-carrier-protein] reductase 2703539 4529237 MAV_2665 Mycobacterium avium 104 3-oxoacyl-[acyl-carrier-protein] reductase YP_881856.1 2702718 D 243243 CDS YP_881857.1 118463758 4528002 complement(2703559..2704677) 1 NC_008595.1 hypothetical protein 2704677 4528002 MAV_2666 Mycobacterium avium 104 hypothetical protein YP_881857.1 2703559 R 243243 CDS YP_881858.1 118466511 4527184 complement(2704781..2705011) 1 NC_008595.1 hypothetical protein 2705011 4527184 MAV_2667 Mycobacterium avium 104 hypothetical protein YP_881858.1 2704781 R 243243 CDS YP_881859.1 118462433 4528296 complement(2705224..2706366) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2706366 4528296 MAV_2668 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881859.1 2705224 R 243243 CDS YP_881860.1 118465358 4529218 complement(2706363..2706566) 1 NC_008595.1 short chain dehydrogenase 2706566 4529218 MAV_2669 Mycobacterium avium 104 short chain dehydrogenase YP_881860.1 2706363 R 243243 CDS YP_881861.1 118462901 4528164 2706695..2707999 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2707999 4528164 MAV_2671 Mycobacterium avium 104 transposase, Mutator family protein YP_881861.1 2706695 D 243243 CDS YP_881862.1 118462357 4527985 complement(2707976..2708665) 1 NC_008595.1 identified by match to protein family HMM PF00106; retinol dehydrogenase 12 2708665 4527985 MAV_2670 Mycobacterium avium 104 retinol dehydrogenase 12 YP_881862.1 2707976 R 243243 CDS YP_881863.1 118465810 4525912 2708730..2710229 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 2710229 4525912 MAV_2672 Mycobacterium avium 104 acyl-CoA synthase YP_881863.1 2708730 D 243243 CDS YP_881864.1 118466692 4530434 2710557..2710922 1 NC_008595.1 hypothetical protein 2710922 4530434 MAV_2673 Mycobacterium avium 104 hypothetical protein YP_881864.1 2710557 D 243243 CDS YP_881865.1 118467147 4527161 complement(2711300..2711560) 1 NC_008595.1 hypothetical protein 2711560 4527161 MAV_2674 Mycobacterium avium 104 hypothetical protein YP_881865.1 2711300 R 243243 CDS YP_881866.1 118464358 4530501 2711640..2713220 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2713220 4530501 MAV_2675 Mycobacterium avium 104 transposase YP_881866.1 2711640 D 243243 CDS YP_881867.1 118465217 4529854 2713217..2714011 1 NC_008595.1 identified by match to protein family HMM PF01695; helper protein 2714011 4529854 MAV_2676 Mycobacterium avium 104 helper protein YP_881867.1 2713217 D 243243 CDS YP_881868.1 118466429 4530173 complement(2714063..2714185) 1 NC_008595.1 hypothetical protein 2714185 4530173 MAV_2677 Mycobacterium avium 104 hypothetical protein YP_881868.1 2714063 R 243243 CDS YP_881869.1 118462873 4527101 2714356..2714631 1 NC_008595.1 transposase 2714631 4527101 MAV_2678 Mycobacterium avium 104 transposase YP_881869.1 2714356 D 243243 CDS YP_881870.1 118466773 4530768 2714631..2715548 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2715548 4530768 MAV_2679 Mycobacterium avium 104 transposase YP_881870.1 2714631 D 243243 CDS YP_881871.1 118464945 4528206 2715631..2716002 1 NC_008595.1 identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073; hydrogenase accessory protein HypB 2716002 hypB 4528206 hypB Mycobacterium avium 104 hydrogenase accessory protein HypB YP_881871.1 2715631 D 243243 CDS YP_881872.1 118465615 4527874 2716404..2717459 1 NC_008595.1 NADH ubiquinone oxidoreductase, 20 kDa subunit 2717459 4527874 MAV_2681 Mycobacterium avium 104 NADH ubiquinone oxidoreductase, 20 kDa subunit YP_881872.1 2716404 D 243243 CDS YP_881873.1 118463710 4530597 2717507..2719303 1 NC_008595.1 identified by match to protein family HMM PF00374; hydrogen:quinone oxidoreductase 2719303 4530597 MAV_2682 Mycobacterium avium 104 hydrogen:quinone oxidoreductase YP_881873.1 2717507 D 243243 CDS YP_881874.1 118464609 4526766 2719307..2720257 1 NC_008595.1 identified by match to protein family HMM PF01106; hypothetical protein 2720257 4526766 MAV_2683 Mycobacterium avium 104 hypothetical protein YP_881874.1 2719307 D 243243 CDS YP_881875.1 118464434 4530255 2720332..2720898 1 NC_008595.1 hypothetical protein 2720898 4530255 MAV_2684 Mycobacterium avium 104 hypothetical protein YP_881875.1 2720332 D 243243 CDS YP_881876.1 118462759 4527849 2720895..2721548 1 NC_008595.1 hypothetical protein 2721548 4527849 MAV_2685 Mycobacterium avium 104 hypothetical protein YP_881876.1 2720895 D 243243 CDS YP_881877.1 118463350 4529884 2721545..2722915 1 NC_008595.1 hypothetical protein 2722915 4529884 MAV_2686 Mycobacterium avium 104 hypothetical protein YP_881877.1 2721545 D 243243 CDS YP_881878.1 118464040 4529012 2722920..2723489 1 NC_008595.1 identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072; peptidase M52, hydrogen uptake protein 2723489 4529012 MAV_2687 Mycobacterium avium 104 peptidase M52, hydrogen uptake protein YP_881878.1 2722920 D 243243 CDS YP_881879.1 118465734 4525697 2723585..2723788 1 NC_008595.1 alpha/beta hydrolase 2723788 4525697 MAV_2688 Mycobacterium avium 104 alpha/beta hydrolase YP_881879.1 2723585 D 243243 CDS YP_881880.1 118463630 4527334 2724085..2724198 1 NC_008595.1 hypothetical protein 2724198 4527334 MAV_2689 Mycobacterium avium 104 hypothetical protein YP_881880.1 2724085 D 243243 CDS YP_881881.1 118464503 4525546 complement(2724520..2725242) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01428; match to protein family HMM TIGR01493; haloacid dehalogenase, type II 2725242 dehII 4525546 dehII Mycobacterium avium 104 haloacid dehalogenase, type II YP_881881.1 2724520 R 243243 CDS YP_881882.1 118464209 4526889 2725778..2727358 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2727358 4526889 MAV_2691 Mycobacterium avium 104 transposase YP_881882.1 2725778 D 243243 CDS YP_881883.1 118466318 4528360 2727355..2728149 1 NC_008595.1 identified by match to protein family HMM PF01695; helper protein 2728149 4528360 MAV_2692 Mycobacterium avium 104 helper protein YP_881883.1 2727355 D 243243 CDS YP_881884.1 118463853 4529952 2728205..2728426 1 NC_008595.1 hypothetical protein 2728426 4529952 MAV_2693 Mycobacterium avium 104 hypothetical protein YP_881884.1 2728205 D 243243 CDS YP_881885.1 118464617 4526774 2728694..2728879 1 NC_008595.1 hypothetical protein 2728879 4526774 MAV_2694 Mycobacterium avium 104 hypothetical protein YP_881885.1 2728694 D 243243 CDS YP_881886.1 118467170 4530140 complement(2728924..2729730) 1 NC_008595.1 identified by match to protein family HMM PF02551; acyl-CoA thioesterase 2729730 4530140 MAV_2695 Mycobacterium avium 104 acyl-CoA thioesterase YP_881886.1 2728924 R 243243 CDS YP_881887.1 118462406 4525716 2729657..2730154 1 NC_008595.1 transposase 2730154 4525716 MAV_2697 Mycobacterium avium 104 transposase YP_881887.1 2729657 D 243243 CDS YP_881888.1 118462572 4528631 complement(2729891..2730730) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 2730730 4528631 MAV_2696 Mycobacterium avium 104 transposase YP_881888.1 2729891 R 243243 CDS YP_881889.1 118466352 4530492 complement(2730808..2731152) 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 2731152 4530492 MAV_2698 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_881889.1 2730808 R 243243 CDS YP_881890.1 118466878 4526697 complement(2731223..2731831) 1 NC_008595.1 hypothetical protein 2731831 4526697 MAV_2699 Mycobacterium avium 104 hypothetical protein YP_881890.1 2731223 R 243243 CDS YP_881891.1 118463032 4528873 complement(2732013..2732852) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2732852 4528873 MAV_2700 Mycobacterium avium 104 short chain dehydrogenase YP_881891.1 2732013 R 243243 CDS YP_881892.1 118462491 4530687 complement(2732843..2734975) 1 NC_008595.1 identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737; acyl-CoA dehydrogenase 2734975 4530687 MAV_2701 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881892.1 2732843 R 243243 CDS YP_881893.1 118462568 4528627 complement(2734982..2736193) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 2736193 4528627 MAV_2702 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_881893.1 2734982 R 243243 CDS YP_881894.1 118464978 4527470 complement(2736204..2737367) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2737367 4527470 MAV_2703 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881894.1 2736204 R 243243 CDS YP_881895.1 118466603 4529369 complement(2737370..2738188) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 2738188 4529369 MAV_2704 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_881895.1 2737370 R 243243 CDS YP_881896.1 118466124 4529757 2738296..2738889 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2738889 4529757 MAV_2705 Mycobacterium avium 104 TetR family transcriptional regulator YP_881896.1 2738296 D 243243 CDS YP_881897.1 118465824 4525496 complement(2738910..2739755) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 2739755 4525496 MAV_2706 Mycobacterium avium 104 alpha/beta hydrolase YP_881897.1 2738910 R 243243 CDS YP_881898.1 118466076 4527343 complement(2741776..2742429) 1 NC_008595.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; metal-dependent phosphohydrolase 2742429 4527343 MAV_2708 Mycobacterium avium 104 metal-dependent phosphohydrolase YP_881898.1 2741776 R 243243 CDS YP_881899.1 118466098 4527727 complement(2742475..2743185) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 2743185 4527727 MAV_2709 Mycobacterium avium 104 short chain dehydrogenase YP_881899.1 2742475 R 243243 CDS YP_881900.1 118464718 4529405 complement(2743366..2743728) 1 NC_008595.1 identified by match to protein family HMM PF00553; cellulose-binding domain-containing protein 2743728 4529405 MAV_2710 Mycobacterium avium 104 cellulose-binding domain-containing protein YP_881900.1 2743366 R 243243 CDS YP_881901.1 118465463 4526231 2744027..2744869 1 NC_008595.1 AraC family transcriptional regulator 2744869 4526231 MAV_2711 Mycobacterium avium 104 AraC family transcriptional regulator YP_881901.1 2744027 D 243243 CDS YP_881902.1 118466159 4528781 2744850..2745224 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 2745224 4528781 MAV_2712 Mycobacterium avium 104 glyoxalase YP_881902.1 2744850 D 243243 CDS YP_881903.1 118466275 4527827 2745375..2745686 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 2745686 4527827 MAV_2713 Mycobacterium avium 104 hypothetical protein YP_881903.1 2745375 D 243243 CDS YP_881904.1 118466475 4527605 complement(2746378..2746734) 1 NC_008595.1 hypothetical protein 2746734 4527605 MAV_2714 Mycobacterium avium 104 hypothetical protein YP_881904.1 2746378 R 243243 CDS YP_881905.1 118462756 4527846 2746759..2748201 1 NC_008595.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase-like protein 2748201 4527846 MAV_2716 Mycobacterium avium 104 biotin carboxylase-like protein YP_881905.1 2746759 D 243243 CDS YP_881906.1 118464048 4529020 2748198..2749373 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 2749373 4529020 MAV_2718 Mycobacterium avium 104 beta-lactamase YP_881906.1 2748198 D 243243 CDS YP_881907.1 118464789 4526713 complement(2749370..2750599) 1 NC_008595.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 2750599 thiI 4526713 thiI Mycobacterium avium 104 thiamine biosynthesis protein ThiI YP_881907.1 2749370 R 243243 CDS YP_881908.1 118464846 4527962 2750773..2751207 1 NC_008595.1 identified by match to protein family HMM PF00011; Hsp20/alpha crystallin family protein 2751207 4527962 MAV_2719 Mycobacterium avium 104 Hsp20/alpha crystallin family protein YP_881908.1 2750773 D 243243 CDS YP_881909.1 118465542 4530018 complement(2751267..2751647) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2751647 4530018 MAV_2720 Mycobacterium avium 104 MerR family transcriptional regulator YP_881909.1 2751267 R 243243 CDS YP_881910.1 118465461 4526229 2751760..2752179 1 NC_008595.1 identified by match to protein family HMM PF00011; 18 kDa antigen 2 2752179 4526229 MAV_2721 Mycobacterium avium 104 18 kDa antigen 2 YP_881910.1 2751760 D 243243 CDS YP_881911.1 118465286 4529322 2752492..2752812 1 NC_008595.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 2752812 4529322 MAV_2722 Mycobacterium avium 104 DnaJ domain-containing protein YP_881911.1 2752492 D 243243 CDS YP_881912.1 118464276 4528231 complement(2752865..2754271) 1 NC_008595.1 identified by match to protein family HMM PF00668; PapA2 protein 2754271 4528231 MAV_2723 Mycobacterium avium 104 PapA2 protein YP_881912.1 2752865 R 243243 CDS YP_881913.1 118467049 4526505 2754245..2754430 1 NC_008595.1 hypothetical protein 2754430 4526505 MAV_2724 Mycobacterium avium 104 hypothetical protein YP_881913.1 2754245 D 243243 CDS YP_881914.1 118462541 4530542 2754921..2755478 1 NC_008595.1 identified by match to protein family HMM PF00254; peptidyl-prolyl cis-trans isomerase domain-containing protein 2755478 4530542 MAV_2725 Mycobacterium avium 104 peptidyl-prolyl cis-trans isomerase domain-containing protein YP_881914.1 2754921 D 243243 CDS YP_881915.1 118462466 4528720 complement(2755526..2756287) 1 NC_008595.1 identified by match to protein family HMM PF00106; acyl-CoA dehydrogenase 2756287 4528720 MAV_2726 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_881915.1 2755526 R 243243 CDS YP_881916.1 118466563 4529112 2756500..2757183 1 NC_008595.1 hypothetical protein 2757183 4529112 MAV_2727 Mycobacterium avium 104 hypothetical protein YP_881916.1 2756500 D 243243 CDS YP_881917.1 118463304 4525999 2757228..2757995 1 NC_008595.1 hypothetical protein 2757995 4525999 MAV_2728 Mycobacterium avium 104 hypothetical protein YP_881917.1 2757228 D 243243 CDS YP_881918.1 118464844 4527960 complement(2758015..2759250) 1 NC_008595.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03106; hydrolase, peptidase M42 family protein 2759250 4527960 MAV_2729 Mycobacterium avium 104 hydrolase, peptidase M42 family protein YP_881918.1 2758015 R 243243 CDS YP_881919.1 118466838 4526947 complement(2759333..2760214) 1 NC_008595.1 identified by match to protein family HMM PF03328; citrate lyase beta chain (Citrase beta chain) (citrate(pro-3S)-lyase beta chain) 2760214 4526947 MAV_2730 Mycobacterium avium 104 citrate lyase beta chain (Citrase beta chain) (citrate(pro-3S)-lyase beta chain) YP_881919.1 2759333 R 243243 CDS YP_881920.1 118467164 4527596 complement(2760242..2760343) 1 NC_008595.1 hypothetical protein 2760343 4527596 MAV_2731 Mycobacterium avium 104 hypothetical protein YP_881920.1 2760242 R 243243 CDS YP_881921.1 118465341 4526654 2760383..2761306 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase 2761306 4526654 MAV_2732 Mycobacterium avium 104 methyltransferase YP_881921.1 2760383 D 243243 CDS YP_881922.1 118466428 4530172 complement(2761320..2762837) 1 NC_008595.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2762837 zwf 4530172 zwf Mycobacterium avium 104 glucose-6-phosphate 1-dehydrogenase YP_881922.1 2761320 R 243243 CDS YP_881923.1 118467169 4527601 2762978..2763160 1 NC_008595.1 hypothetical protein 2763160 4527601 MAV_2734 Mycobacterium avium 104 hypothetical protein YP_881923.1 2762978 D 243243 CDS YP_881924.1 118464626 4526783 complement(2763186..2764163) 1 NC_008595.1 hypothetical protein 2764163 4526783 MAV_2735 Mycobacterium avium 104 hypothetical protein YP_881924.1 2763186 R 243243 CDS YP_881925.1 118463861 4529960 complement(2764240..2765751) 1 NC_008595.1 identified by match to protein family HMM PF01494; hypothetical protein 2765751 4529960 MAV_2736 Mycobacterium avium 104 hypothetical protein YP_881925.1 2764240 R 243243 CDS YP_881926.1 118464254 4527439 complement(2765831..2769784) 1 NC_008595.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967; ATP-dependent helicase HrpA 2769784 hrpA 4527439 hrpA Mycobacterium avium 104 ATP-dependent helicase HrpA YP_881926.1 2765831 R 243243 CDS YP_881927.1 118462383 4529197 2769960..2770943 1 NC_008595.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2770943 4529197 MAV_2738 Mycobacterium avium 104 diguanylate cyclase YP_881927.1 2769960 D 243243 CDS YP_881928.1 118465303 4526557 2771067..2772041 1 NC_008595.1 identified by match to protein family HMM PF03631; hypothetical protein 2772041 4526557 MAV_2739 Mycobacterium avium 104 hypothetical protein YP_881928.1 2771067 D 243243 CDS YP_881929.1 118464851 4527967 2772100..2772873 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2772873 4527967 MAV_2740 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_881929.1 2772100 D 243243 CDS YP_881930.1 118465549 4525797 2773002..2773592 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase, cutinase 2773592 4525797 MAV_2741 Mycobacterium avium 104 serine esterase, cutinase YP_881930.1 2773002 D 243243 CDS YP_881931.1 118466449 4527122 2773605..2774264 1 NC_008595.1 hypothetical protein 2774264 4527122 MAV_2742 Mycobacterium avium 104 hypothetical protein YP_881931.1 2773605 D 243243 CDS YP_881932.1 118463810 4526065 2774297..2774551 1 NC_008595.1 hypothetical protein 2774551 4526065 MAV_2743 Mycobacterium avium 104 hypothetical protein YP_881932.1 2774297 D 243243 CDS YP_881933.1 118467179 4530149 complement(2774673..2775515) 1 NC_008595.1 identified by match to protein family HMM PF03473; mosc domain-containing protein 2775515 4530149 MAV_2744 Mycobacterium avium 104 mosc domain-containing protein YP_881933.1 2774673 R 243243 CDS YP_881934.1 118465374 4529235 complement(2775593..2776321) 1 NC_008595.1 hypothetical protein 2776321 4529235 MAV_2745 Mycobacterium avium 104 hypothetical protein YP_881934.1 2775593 R 243243 CDS YP_881935.1 118466099 4527728 complement(2776455..2777840) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2777840 4527728 MAV_2746 Mycobacterium avium 104 PPE family protein YP_881935.1 2776455 R 243243 CDS YP_881936.1 118464301 4526631 2778301..2779473 1 NC_008595.1 identified by match to protein family HMM PF03033; rhamnosyltransferase RtfA 2779473 4526631 MAV_2747 Mycobacterium avium 104 rhamnosyltransferase RtfA YP_881936.1 2778301 D 243243 CDS YP_881937.1 118464967 4528707 2779532..2780581 1 NC_008595.1 hypothetical protein 2780581 4528707 MAV_2748 Mycobacterium avium 104 hypothetical protein YP_881937.1 2779532 D 243243 CDS YP_881938.1 118463086 4528909 complement(2780587..2782107) 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM PF01266; FAD dependent oxidoreductase 2782107 4528909 MAV_2749 Mycobacterium avium 104 FAD dependent oxidoreductase YP_881938.1 2780587 R 243243 CDS YP_881939.1 118463848 4529947 complement(2782152..2782931) 1 NC_008595.1 hypothetical protein 2782931 4529947 MAV_2750 Mycobacterium avium 104 hypothetical protein YP_881939.1 2782152 R 243243 CDS YP_881940.1 118466653 4528092 2783054..2784337 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 2784337 4528092 MAV_2751 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_881940.1 2783054 D 243243 CDS YP_881941.1 118467206 4528441 2784467..2784871 1 NC_008595.1 identified by match to protein family HMM PF01475; Fur family transcriptional regulator 2784871 4528441 MAV_2752 Mycobacterium avium 104 Fur family transcriptional regulator YP_881941.1 2784467 D 243243 CDS YP_881942.1 118465627 4528744 2784908..2787154 1 NC_008595.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 2787154 katG 4528744 katG Mycobacterium avium 104 catalase/peroxidase HPI YP_881942.1 2784908 D 243243 CDS YP_881943.1 118465160 4529250 complement(2787207..2788022) 1 NC_008595.1 hypothetical protein 2788022 4529250 MAV_2754 Mycobacterium avium 104 hypothetical protein YP_881943.1 2787207 R 243243 CDS YP_881944.1 118464593 4530104 2788416..2789606 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase 2789606 4530104 MAV_2755 Mycobacterium avium 104 glycosyl transferase YP_881944.1 2788416 D 243243 CDS YP_881945.1 118464011 4529273 2789600..2790358 1 NC_008595.1 methyltransferase 2790358 4529273 MAV_2756 Mycobacterium avium 104 methyltransferase YP_881945.1 2789600 D 243243 CDS YP_881946.1 118463405 4528032 2790345..2791415 1 NC_008595.1 hypothetical protein 2791415 4528032 MAV_2757 Mycobacterium avium 104 hypothetical protein YP_881946.1 2790345 D 243243 CDS YP_881947.1 118462816 4529036 complement(2791420..2792079) 1 NC_008595.1 secreted protein 2792079 4529036 MAV_2758 Mycobacterium avium 104 secreted protein YP_881947.1 2791420 R 243243 CDS YP_881948.1 118466142 4527908 2792361..2792909 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase, cutinase 2792909 4527908 MAV_2759 Mycobacterium avium 104 serine esterase, cutinase YP_881948.1 2792361 D 243243 CDS YP_881949.1 118462623 4526425 complement(2793098..2793217) 1 NC_008595.1 hypothetical protein 2793217 4526425 MAV_2760 Mycobacterium avium 104 hypothetical protein YP_881949.1 2793098 R 243243 CDS YP_881950.1 118463019 4526312 2793560..2794381 1 NC_008595.1 identified by match to protein family HMM PF00722; match to protein family HMM TIGR01409; glycosyl hydrolases family protein 16 2794381 4526312 MAV_2761 Mycobacterium avium 104 glycosyl hydrolases family protein 16 YP_881950.1 2793560 D 243243 CDS YP_881951.1 118462916 4526005 complement(2794400..2795245) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 2795245 4526005 MAV_2762 Mycobacterium avium 104 methyltransferase, putative, family protein YP_881951.1 2794400 R 243243 CDS YP_881952.1 118465008 4526274 complement(2795275..2795946) 1 NC_008595.1 hypothetical protein 2795946 4526274 MAV_2763 Mycobacterium avium 104 hypothetical protein YP_881952.1 2795275 R 243243 CDS YP_881953.1 118462373 4529186 2796087..2796341 1 NC_008595.1 hypothetical protein 2796341 4529186 MAV_2764 Mycobacterium avium 104 hypothetical protein YP_881953.1 2796087 D 243243 CDS YP_881954.1 118467317 4530310 complement(2796413..2797867) 1 NC_008595.1 identified by match to protein family HMM PF00171; P-cumic aldehyde dehydrogenase 2797867 4530310 MAV_2765 Mycobacterium avium 104 P-cumic aldehyde dehydrogenase YP_881954.1 2796413 R 243243 CDS YP_881955.1 118462897 4528159 complement(2797995..2798918) 1 NC_008595.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase 2798918 4528159 MAV_2766 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_881955.1 2797995 R 243243 CDS YP_881956.1 118465873 4527515 complement(2798949..2800133) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 2800133 4527515 MAV_2767 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_881956.1 2798949 R 243243 CDS YP_881957.1 118464542 4530412 2800220..2800579 1 NC_008595.1 hypothetical protein 2800579 4530412 MAV_2768 Mycobacterium avium 104 hypothetical protein YP_881957.1 2800220 D 243243 CDS YP_881958.1 118465067 4527043 2800657..2801538 1 NC_008595.1 identified by match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 2801538 4527043 MAV_2769 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_881958.1 2800657 D 243243 CDS YP_881959.1 118463413 4530050 complement(2801551..2802045) 1 NC_008595.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2802045 tpx 4530050 tpx Mycobacterium avium 104 thiol peroxidase YP_881959.1 2801551 R 243243 CDS YP_881960.1 118465696 4530318 complement(2802983..2803105) 1 NC_008595.1 hypothetical protein 2803105 4530318 MAV_2771 Mycobacterium avium 104 hypothetical protein YP_881960.1 2802983 R 243243 CDS YP_881961.1 118463154 4527792 2803152..2803895 1 NC_008595.1 identified by match to protein family HMM PF01965; DJ-1/PfpI family protein 2803895 4527792 MAV_2773 Mycobacterium avium 104 DJ-1/PfpI family protein YP_881961.1 2803152 D 243243 CDS YP_881962.1 118464577 4530281 complement(2803896..2804381) 1 NC_008595.1 hypothetical protein 2804381 4530281 MAV_2774 Mycobacterium avium 104 hypothetical protein YP_881962.1 2803896 R 243243 CDS YP_881963.1 118462647 4529388 2804455..2805219 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2805219 4529388 MAV_2775 Mycobacterium avium 104 short chain dehydrogenase YP_881963.1 2804455 D 243243 CDS YP_881964.1 118463472 4525525 complement(2805253..2805921) 1 NC_008595.1 hypothetical protein 2805921 4525525 MAV_2776 Mycobacterium avium 104 hypothetical protein YP_881964.1 2805253 R 243243 CDS YP_881965.2 161579547 4528783 complement(2805975..2807813) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; fatty-acid--CoA ligase 2807813 4528783 MAV_2777 Mycobacterium avium 104 fatty-acid--CoA ligase YP_881965.2 2805975 R 243243 CDS YP_881966.1 118466784 4529342 2807994..2808461 1 NC_008595.1 hypothetical protein 2808461 4529342 MAV_2778 Mycobacterium avium 104 hypothetical protein YP_881966.1 2807994 D 243243 CDS YP_881967.1 118465121 4530474 complement(2808503..2809666) 1 NC_008595.1 identified by match to protein family HMM PF00296; limonene 1,2-monooxygenase 2809666 4530474 MAV_2779 Mycobacterium avium 104 limonene 1,2-monooxygenase YP_881967.1 2808503 R 243243 CDS YP_881968.1 118465673 4526745 complement(2809850..2810230) 1 NC_008595.1 hypothetical protein 2810230 4526745 MAV_2780 Mycobacterium avium 104 hypothetical protein YP_881968.1 2809850 R 243243 CDS YP_881969.1 118464681 4528376 complement(2810353..2812641) 1 NC_008595.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 2812641 aceA 4528376 aceA Mycobacterium avium 104 isocitrate lyase YP_881969.1 2810353 R 243243 CDS YP_881970.1 118465221 4529858 complement(2812860..2813573) 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 2813573 4529858 MAV_2782 Mycobacterium avium 104 metallo-beta-lactamase YP_881970.1 2812860 R 243243 CDS YP_881971.1 118465456 4526224 2813692..2814015 1 NC_008595.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 2814015 4526224 MAV_2783 Mycobacterium avium 104 ArsR family transcriptional regulator YP_881971.1 2813692 D 243243 CDS YP_881972.1 118464923 4528563 2814012..2814419 1 NC_008595.1 hypothetical protein 2814419 4528563 MAV_2784 Mycobacterium avium 104 hypothetical protein YP_881972.1 2814012 D 243243 CDS YP_881973.1 118463984 4530343 2814470..2814919 1 NC_008595.1 similar to streptomyces cyclase/dehydrase; identified by match to protein family HMM PF03364; cyclase/dehydrase 2814919 4530343 MAV_2785 Mycobacterium avium 104 cyclase/dehydrase YP_881973.1 2814470 D 243243 CDS YP_881974.1 118464553 4530772 2815007..2815615 1 NC_008595.1 identified by match to protein family HMM PF01161; match to protein family HMM TIGR00481; phosphatidylethanolamine-binding protein 2815615 4530772 MAV_2786 Mycobacterium avium 104 phosphatidylethanolamine-binding protein YP_881974.1 2815007 D 243243 CDS YP_881975.1 118462836 4528651 complement(2815625..2817193) 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593; FAD dependent oxidoreductase, putative 2817193 4528651 MAV_2787 Mycobacterium avium 104 FAD dependent oxidoreductase, putative YP_881975.1 2815625 R 243243 CDS YP_881976.1 118463380 4528958 2817302..2817901 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2817901 4528958 MAV_2788 Mycobacterium avium 104 TetR family transcriptional regulator YP_881976.1 2817302 D 243243 CDS YP_881977.1 118466169 4526200 complement(2817920..2818813) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2818813 4526200 MAV_2789 Mycobacterium avium 104 LysR family transcriptional regulator YP_881977.1 2817920 R 243243 CDS YP_881978.1 118466774 4530769 2818899..2819291 1 NC_008595.1 identified by match to protein family HMM PF01361; malonate semialdehyde decarboxylase 2819291 4530769 MAV_2790 Mycobacterium avium 104 malonate semialdehyde decarboxylase YP_881978.1 2818899 D 243243 CDS YP_881979.1 118465049 4525828 2819288..2820271 1 NC_008595.1 identified by similarity to GB:AAF98273.1; match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 2820271 4525828 MAV_2791 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_881979.1 2819288 D 243243 CDS YP_881980.1 118464292 4529580 2820347..2820487 1 NC_008595.1 hypothetical protein 2820487 4529580 MAV_2792 Mycobacterium avium 104 hypothetical protein YP_881980.1 2820347 D 243243 CDS YP_881981.1 118465238 4525609 2821149..2821643 1 NC_008595.1 hypothetical protein 2821643 4525609 MAV_2794 Mycobacterium avium 104 hypothetical protein YP_881981.1 2821149 D 243243 CDS YP_881982.1 118464436 4525967 2821786..2822367 1 NC_008595.1 hypothetical protein 2822367 4525967 MAV_2795 Mycobacterium avium 104 hypothetical protein YP_881982.1 2821786 D 243243 CDS YP_881983.1 118462416 4525726 2822398..2823363 1 NC_008595.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase 2823363 4525726 MAV_2796 Mycobacterium avium 104 FAD dependent oxidoreductase YP_881983.1 2822398 D 243243 CDS YP_881984.1 118466499 4525582 complement(2823366..2823755) 1 NC_008595.1 identified by match to protein family HMM PF04020; hypothetical protein 2823755 4525582 MAV_2797 Mycobacterium avium 104 hypothetical protein YP_881984.1 2823366 R 243243 CDS YP_881985.1 118467031 4526543 complement(2823801..2824868) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2824868 4526543 MAV_2798 Mycobacterium avium 104 amidohydrolase YP_881985.1 2823801 R 243243 CDS YP_881986.1 118465387 4529679 2824867..2826219 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891; MFS transporter, sialate:H+ symporter (SHS) family protein 2826219 4529679 MAV_2799 Mycobacterium avium 104 MFS transporter, sialate:H+ symporter (SHS) family protein YP_881986.1 2824867 D 243243 CDS YP_881987.1 118465937 4528496 complement(2826297..2827601) 1 NC_008595.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A 2827601 4528496 MAV_2800 Mycobacterium avium 104 competence damage-inducible protein A YP_881987.1 2826297 R 243243 CDS YP_881988.1 118463611 4527558 complement(2827661..2827966) 1 NC_008595.1 identified by match to protein family HMM PF01910; match to protein family HMM TIGR00106; hypothetical protein 2827966 4527558 MAV_2801 Mycobacterium avium 104 hypothetical protein YP_881988.1 2827661 R 243243 CDS YP_881989.1 118464219 4526899 2828052..2828483 1 NC_008595.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2828483 dtd 4526899 dtd Mycobacterium avium 104 D-tyrosyl-tRNA(Tyr) deacylase YP_881989.1 2828052 D 243243 CDS YP_881990.1 118466635 4526991 2828515..2829423 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 2829423 4526991 MAV_2803 Mycobacterium avium 104 methyltransferase, putative, family protein YP_881990.1 2828515 D 243243 CDS YP_881991.1 118465037 4525816 complement(2829430..2830455) 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 2830455 4525816 MAV_2804 Mycobacterium avium 104 zinc-binding dehydrogenase YP_881991.1 2829430 R 243243 CDS YP_881992.1 118462632 4526434 complement(2830487..2832439) 1 NC_008595.1 4-hydroxyacetophenone monooxygenase 2832439 4526434 MAV_2805 Mycobacterium avium 104 4-hydroxyacetophenone monooxygenase YP_881992.1 2830487 R 243243 CDS YP_881993.1 118463168 4529870 complement(2832565..2833974) 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 2833974 4529870 MAV_2806 Mycobacterium avium 104 hypothetical protein YP_881993.1 2832565 R 243243 CDS YP_881994.1 118464099 4525860 2834123..2835253 1 NC_008595.1 identified by match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 2835253 4525860 MAV_2807 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_881994.1 2834123 D 243243 CDS YP_881995.1 118464696 4527885 complement(2835262..2835492) 1 NC_008595.1 hypothetical protein 2835492 4527885 MAV_2808 Mycobacterium avium 104 hypothetical protein YP_881995.1 2835262 R 243243 CDS YP_881996.1 118463564 4530719 complement(2835629..2835958) 1 NC_008595.1 hypothetical protein 2835958 4530719 MAV_2809 Mycobacterium avium 104 hypothetical protein YP_881996.1 2835629 R 243243 CDS YP_881997.1 118463365 4529899 complement(2835955..2836353) 1 NC_008595.1 hypothetical protein 2836353 4529899 MAV_2810 Mycobacterium avium 104 hypothetical protein YP_881997.1 2835955 R 243243 CDS YP_881998.1 118464362 4530505 2836566..2837852 1 NC_008595.1 cytochrome P450 124 2837852 4530505 MAV_2811 Mycobacterium avium 104 cytochrome P450 124 YP_881998.1 2836566 D 243243 CDS YP_881999.1 118465236 4525607 2837922..2838890 1 NC_008595.1 identified by match to protein family HMM PF00107; aldehyde dehydrogenase 2838890 4525607 MAV_2812 Mycobacterium avium 104 aldehyde dehydrogenase YP_881999.1 2837922 D 243243 CDS YP_882000.1 118465817 4525920 2838935..2839501 1 NC_008595.1 hypothetical protein 2839501 4525920 MAV_2813 Mycobacterium avium 104 hypothetical protein YP_882000.1 2838935 D 243243 CDS YP_882001.1 118464401 4530795 complement(2839518..2840645) 1 NC_008595.1 hypothetical protein 2840645 4530795 MAV_2814 Mycobacterium avium 104 hypothetical protein YP_882001.1 2839518 R 243243 CDS YP_882002.1 118463877 4527755 2840912..2841118 1 NC_008595.1 hypothetical protein 2841118 4527755 MAV_2815 Mycobacterium avium 104 hypothetical protein YP_882002.1 2840912 D 243243 CDS YP_882003.1 118465697 4530319 2841247..2842239 1 NC_008595.1 identified by match to protein family HMM PF00756; antigen 85-B 2842239 4530319 MAV_2816 Mycobacterium avium 104 antigen 85-B YP_882003.1 2841247 D 243243 CDS YP_882004.1 118464988 4527480 2842350..2842913 1 NC_008595.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 2842913 4527480 MAV_2817 Mycobacterium avium 104 chorismate mutase YP_882004.1 2842350 D 243243 CDS YP_882005.1 118464653 4528250 2843127..2843456 1 NC_008595.1 identified by match to protein family HMM PF06737; resuscitation-promoting factor RpfA 2843456 4528250 MAV_2818 Mycobacterium avium 104 resuscitation-promoting factor RpfA YP_882005.1 2843127 D 243243 CDS YP_882006.1 118463871 4527749 2843510..2843971 1 NC_008595.1 similar to streptomyces cyclase/dehydrase; identified by match to protein family HMM PF03364; cyclase/dehydrase 2843971 4527749 MAV_2819 Mycobacterium avium 104 cyclase/dehydrase YP_882006.1 2843510 D 243243 CDS YP_882007.1 118463489 4529068 2843968..2844801 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2844801 4529068 MAV_2820 Mycobacterium avium 104 short chain dehydrogenase YP_882007.1 2843968 D 243243 CDS YP_882008.1 118462763 4527853 2844814..2845236 1 NC_008595.1 LppE protein 2845236 4527853 MAV_2821 Mycobacterium avium 104 LppE protein YP_882008.1 2844814 D 243243 CDS YP_882009.1 118466270 4527822 2845293..2846645 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 2846645 4527822 MAV_2822 Mycobacterium avium 104 P450 heme-thiolate protein YP_882009.1 2845293 D 243243 CDS YP_882010.1 118462964 4526332 2846707..2847150 1 NC_008595.1 identified by match to protein family HMM PF07366; match to protein family HMM PF07858; limonene-1,2-epoxide hydrolase catalytic domain-containing superfamily protein 2847150 4526332 MAV_2823 Mycobacterium avium 104 limonene-1,2-epoxide hydrolase catalytic domain-containing superfamily protein YP_882010.1 2846707 D 243243 CDS YP_882011.1 118465119 4530471 complement(2847159..2848337) 1 NC_008595.1 hypothetical protein 2848337 4530471 MAV_2824 Mycobacterium avium 104 hypothetical protein YP_882011.1 2847159 R 243243 CDS YP_882012.1 118463832 4526050 2848438..2848551 1 NC_008595.1 hypothetical protein 2848551 4526050 MAV_2825 Mycobacterium avium 104 hypothetical protein YP_882012.1 2848438 D 243243 CDS YP_882013.1 118462544 4530545 complement(2848561..2849874) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2849874 4530545 MAV_2826 Mycobacterium avium 104 transposase, Mutator family protein YP_882013.1 2848561 R 243243 CDS YP_882014.1 118467020 4529490 2849862..2851133 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2851133 4529490 MAV_2827 Mycobacterium avium 104 transposase, Mutator family protein YP_882014.1 2849862 D 243243 CDS YP_882015.1 118465653 4526178 complement(2851796..2852914) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 2852914 4526178 MAV_2828 Mycobacterium avium 104 amidohydrolase YP_882015.1 2851796 R 243243 CDS YP_882016.1 118464948 4528210 complement(2852925..2854277) 1 NC_008595.1 identified by match to protein family HMM PF00120; glutamine synthetase catalytic domain 2854277 glnA 4528210 glnA Mycobacterium avium 104 glutamine synthetase catalytic domain YP_882016.1 2852925 R 243243 CDS YP_882017.1 118464241 4528614 complement(2854319..2855200) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2855200 4528614 MAV_2830 Mycobacterium avium 104 hypothetical protein YP_882017.1 2854319 R 243243 CDS YP_882018.1 118466509 4525592 complement(2855233..2855727) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 2855727 pcaC 4525592 pcaC Mycobacterium avium 104 hypothetical protein YP_882018.1 2855233 R 243243 CDS YP_882019.1 118467257 4526092 complement(2855782..2857830) 1 NC_008595.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; drug transporter 2857830 4526092 MAV_2832 Mycobacterium avium 104 drug transporter YP_882019.1 2855782 R 243243 CDS YP_882020.1 118465373 4529234 complement(2857951..2858430) 1 NC_008595.1 identified by match to protein family HMM PF00210; match to protein family HMM TIGR00754; bacterioferritin 2858430 bfr 4529234 bfr Mycobacterium avium 104 bacterioferritin YP_882020.1 2857951 R 243243 CDS YP_882021.1 118464869 4530705 2858781..2858966 1 NC_008595.1 identified by match to protein family HMM PF04324; hypothetical protein 2858966 4530705 MAV_2834 Mycobacterium avium 104 hypothetical protein YP_882021.1 2858781 D 243243 CDS YP_882022.1 118463557 4526824 complement(2859023..2859772) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2859772 4526824 MAV_2835 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_882022.1 2859023 R 243243 CDS YP_882023.1 118462404 4525714 complement(2859787..2860230) 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 2860230 4525714 MAV_2836 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_882023.1 2859787 R 243243 CDS YP_882024.1 118462683 4530611 complement(2860241..2860942) 1 NC_008595.1 hypothetical protein 2860942 4530611 MAV_2837 Mycobacterium avium 104 hypothetical protein YP_882024.1 2860241 R 243243 CDS YP_882025.1 118463106 4527168 complement(2860979..2861914) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; hydrogen peroxide-inducible genes activator 2861914 4527168 MAV_2838 Mycobacterium avium 104 hydrogen peroxide-inducible genes activator YP_882025.1 2860979 R 243243 CDS YP_882026.1 118467085 4526385 2862029..2862616 1 NC_008595.1 identified by match to protein family HMM PF00578; alkylhydroperoxide reductase 2862616 4526385 MAV_2839 Mycobacterium avium 104 alkylhydroperoxide reductase YP_882026.1 2862029 D 243243 CDS YP_882027.1 118465273 4527294 2862656..2863192 1 NC_008595.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00777; match to protein family HMM TIGR00778; alkylhydroperoxidase, AhpD family protein 2863192 ahpD 4527294 ahpD Mycobacterium avium 104 alkylhydroperoxidase, AhpD family protein YP_882027.1 2862656 D 243243 CDS YP_882028.1 118462356 4527984 2863215..2864537 1 NC_008595.1 identified by match to protein family HMM PF00128; alpha-amylase 3 2864537 4527984 MAV_2842 Mycobacterium avium 104 alpha-amylase 3 YP_882028.1 2863215 D 243243 CDS YP_882029.1 118464736 4529423 complement(2864534..2864971) 1 NC_008595.1 hypothetical protein 2864971 4529423 MAV_2841 Mycobacterium avium 104 hypothetical protein YP_882029.1 2864534 R 243243 CDS YP_882030.1 118464373 4530516 2864990..2866252 1 NC_008595.1 identified by match to protein family HMM PF01070; LldD2 protein 2866252 4530516 MAV_2843 Mycobacterium avium 104 LldD2 protein YP_882030.1 2864990 D 243243 CDS YP_882031.1 118465278 4527299 2868767..2869144 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 2869144 4527299 MAV_2845 Mycobacterium avium 104 hypothetical protein YP_882031.1 2868767 D 243243 CDS YP_882032.1 118463387 4528014 2869185..2869517 1 NC_008595.1 hypothetical protein 2869517 4528014 MAV_2846 Mycobacterium avium 104 hypothetical protein YP_882032.1 2869185 D 243243 CDS YP_882033.1 118463692 4530579 2869560..2870195 1 NC_008595.1 hypothetical protein 2870195 4530579 MAV_2847 Mycobacterium avium 104 hypothetical protein YP_882033.1 2869560 D 243243 CDS YP_882034.1 118464472 4527065 2870203..2870928 1 NC_008595.1 identified by match to protein family HMM PF01904; hypothetical protein 2870928 4527065 MAV_2848 Mycobacterium avium 104 hypothetical protein YP_882034.1 2870203 D 243243 CDS YP_882035.1 118462272 4529277 2870975..2872207 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; anthranilate dioxygenase reductase 2872207 4529277 MAV_2849 Mycobacterium avium 104 anthranilate dioxygenase reductase YP_882035.1 2870975 D 243243 CDS YP_882036.1 118462986 4527414 complement(2872212..2874341) 1 NC_008595.1 identified by match to protein family HMM PF01370; hypothetical protein 2874341 4527414 MAV_2850 Mycobacterium avium 104 hypothetical protein YP_882036.1 2872212 R 243243 CDS YP_882037.1 118466577 4527367 complement(2874473..2875957) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 2875957 4527367 MAV_2851 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_882037.1 2874473 R 243243 CDS YP_882038.1 118467261 4526096 complement(2875976..2878420) 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 2878420 4526096 MAV_2852 Mycobacterium avium 104 caib/baif family protein YP_882038.1 2875976 R 243243 CDS YP_882039.1 118465765 4530458 2878610..2879527 1 NC_008595.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 2879527 4530458 MAV_2853 Mycobacterium avium 104 undecaprenyl pyrophosphate phosphatase YP_882039.1 2878610 D 243243 CDS YP_882040.1 118464745 4529432 2879624..2880472 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2880472 4529432 MAV_2854 Mycobacterium avium 104 short chain dehydrogenase YP_882040.1 2879624 D 243243 CDS YP_882041.1 118464118 4526289 2880517..2882931 1 NC_008595.1 identified by match to protein family HMM PF03894; phosphoketolase 2882931 xfp 4526289 xfp Mycobacterium avium 104 phosphoketolase YP_882041.1 2880517 D 243243 CDS YP_882042.1 118464072 4528385 2883035..2883790 1 NC_008595.1 identified by match to protein family HMM PF02517; caax amino protease 2883790 4528385 MAV_2856 Mycobacterium avium 104 caax amino protease YP_882042.1 2883035 D 243243 CDS YP_882043.1 118463487 4529066 complement(2883804..2884820) 1 NC_008595.1 identified by match to protein family HMM PF00107; match to protein family HMM TIGR02822; zinc-binding alcohol dehydrogenase 2884820 4529066 MAV_2857 Mycobacterium avium 104 zinc-binding alcohol dehydrogenase YP_882043.1 2883804 R 243243 CDS YP_882044.1 118465488 4527241 complement(2884880..2885230) 1 NC_008595.1 identified by match to protein family HMM PF04226; integral membrane protein 2885230 4527241 MAV_2858 Mycobacterium avium 104 integral membrane protein YP_882044.1 2884880 R 243243 CDS YP_882045.1 118464964 4528704 complement(2885325..2886482) 1 NC_008595.1 identified by match to protein family HMM PF07174; ModD protein 2886482 4528704 MAV_2859 Mycobacterium avium 104 ModD protein YP_882045.1 2885325 R 243243 CDS YP_882046.1 118466324 4528755 complement(2886604..2887719) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; molybdenum import ATP-binding protein ModC 2887719 4528755 MAV_2860 Mycobacterium avium 104 molybdenum import ATP-binding protein ModC YP_882046.1 2886604 R 243243 CDS YP_882047.1 118465476 4527229 complement(2887729..2888493) 1 NC_008595.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01581; match to protein family HMM TIGR02141; molybdate ABC transporter permease 2888493 modB 4527229 modB Mycobacterium avium 104 molybdate ABC transporter permease YP_882047.1 2887729 R 243243 CDS YP_882048.1 118462691 4526671 complement(2888668..2889777) 1 NC_008595.1 hypothetical protein 2889777 4526671 MAV_2862 Mycobacterium avium 104 hypothetical protein YP_882048.1 2888668 R 243243 CDS YP_882049.1 118466886 4526705 complement(2890037..2890804) 1 NC_008595.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256; molybdate ABC transporter periplasmic molybdate-binding protein 2890804 modA 4526705 modA Mycobacterium avium 104 molybdate ABC transporter periplasmic molybdate-binding protein YP_882049.1 2890037 R 243243 CDS YP_882050.1 118463407 4530044 2891085..2891756 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 2891756 4530044 MAV_2864 Mycobacterium avium 104 short chain dehydrogenase YP_882050.1 2891085 D 243243 CDS YP_882051.1 118465698 4530320 2891810..2892727 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2892727 4530320 MAV_2865 Mycobacterium avium 104 hypothetical protein YP_882051.1 2891810 D 243243 CDS YP_882052.1 118464629 4528964 2892843..2893226 1 NC_008595.1 hypothetical protein 2893226 4528964 MAV_2866 Mycobacterium avium 104 hypothetical protein YP_882052.1 2892843 D 243243 CDS YP_882053.1 118463906 4525837 2893405..2894790 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; DoxD family protein/pyridine nucleotide-disulfide oxidoreductase 2894790 4525837 MAV_2867 Mycobacterium avium 104 DoxD family protein/pyridine nucleotide-disulfide oxidoreductase YP_882053.1 2893405 D 243243 CDS YP_882054.1 118463432 4528311 complement(2894898..2895320) 1 NC_008595.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 2895320 4528311 MAV_2868 Mycobacterium avium 104 hypothetical protein YP_882054.1 2894898 R 243243 CDS YP_882055.1 118462829 4528643 2895746..2896165 1 NC_008595.1 identified by match to protein family HMM PF03965; CopY family transcriptional regulator 2896165 4528643 MAV_2869 Mycobacterium avium 104 CopY family transcriptional regulator YP_882055.1 2895746 D 243243 CDS YP_882056.1 118464630 4528965 2896180..2897130 1 NC_008595.1 identified by match to protein family HMM PF01435; match to protein family HMM PF05569; integral membrane protein 2897130 4528965 MAV_2870 Mycobacterium avium 104 integral membrane protein YP_882056.1 2896180 D 243243 CDS YP_882057.1 118463874 4527752 2897206..2898690 1 NC_008595.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2898690 gnd 4527752 gnd Mycobacterium avium 104 6-phosphogluconate dehydrogenase YP_882057.1 2897206 D 243243 CDS YP_882058.1 118463441 4528321 2898730..2900166 1 NC_008595.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 2900166 4528321 MAV_2872 Mycobacterium avium 104 inosine 5-monophosphate dehydrogenase YP_882058.1 2898730 D 243243 CDS YP_882059.1 118462750 4527840 2900251..2900556 1 NC_008595.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2900556 4527840 MAV_2873 Mycobacterium avium 104 acyl carrier protein YP_882059.1 2900251 D 243243 CDS YP_882060.1 118466817 4527382 2900549..2902114 1 NC_008595.1 converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; long-chain-fatty-acid--[acyl-carrier-protein] ligase 2902114 4527382 MAV_2874 Mycobacterium avium 104 long-chain-fatty-acid--[acyl-carrier-protein] ligase YP_882060.1 2900549 D 243243 CDS YP_882061.1 118462712 4530086 2902115..2903290 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 2903290 4530086 MAV_2876 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882061.1 2902115 D 243243 CDS YP_882062.1 118466022 4529908 complement(2903257..2903697) 1 NC_008595.1 hypothetical protein 2903697 4529908 MAV_2875 Mycobacterium avium 104 hypothetical protein YP_882062.1 2903257 R 243243 CDS YP_882063.1 118466880 4526699 complement(2903709..2904185) 1 NC_008595.1 hypothetical protein 2904185 4526699 MAV_2877 Mycobacterium avium 104 hypothetical protein YP_882063.1 2903709 R 243243 CDS YP_882064.1 118466927 4527762 2904219..2905583 1 NC_008595.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain-containing protein 2905583 4527762 MAV_2878 Mycobacterium avium 104 CBS domain-containing protein YP_882064.1 2904219 D 243243 CDS YP_882065.1 118462853 4526035 2905580..2906620 1 NC_008595.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; CBS domain-containing protein 2906620 4526035 MAV_2879 Mycobacterium avium 104 CBS domain-containing protein YP_882065.1 2905580 D 243243 CDS YP_882066.1 118462305 4525650 2906905..2909109 1 NC_008595.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 2909109 glcB 4525650 glcB Mycobacterium avium 104 malate synthase G YP_882066.1 2906905 D 243243 CDS YP_882067.1 118463060 4528340 2909210..2911261 1 NC_008595.1 hypothetical protein 2911261 4528340 MAV_2881 Mycobacterium avium 104 hypothetical protein YP_882067.1 2909210 D 243243 CDS YP_882068.1 118462428 4528291 2911532..2912509 1 NC_008595.1 hypothetical protein 2912509 4528291 MAV_2882 Mycobacterium avium 104 hypothetical protein YP_882068.1 2911532 D 243243 CDS YP_882069.1 118467081 4526381 2912580..2913209 1 NC_008595.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00440; TetR family transcriptional regulator 2913209 4526381 MAV_2883 Mycobacterium avium 104 TetR family transcriptional regulator YP_882069.1 2912580 D 243243 CDS YP_882070.1 118466514 4527187 complement(2913237..2916062) 1 NC_008595.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2916062 gcvP 4527187 gcvP Mycobacterium avium 104 glycine dehydrogenase YP_882070.1 2913237 R 243243 CDS YP_882071.1 118465947 4527943 complement(2916396..2917025) 1 NC_008595.1 MerR family transcriptional regulator 2917025 4527943 MAV_2885 Mycobacterium avium 104 MerR family transcriptional regulator YP_882071.1 2916396 R 243243 CDS YP_882072.1 118466898 4528412 complement(2917309..2917749) 1 NC_008595.1 identified by match to protein family HMM PF02577; hypothetical protein 2917749 4528412 MAV_2886 Mycobacterium avium 104 hypothetical protein YP_882072.1 2917309 R 243243 CDS YP_882073.1 118467054 4526510 complement(2917916..2918668) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2918668 4526510 MAV_2887 Mycobacterium avium 104 MerR family transcriptional regulator YP_882073.1 2917916 R 243243 CDS YP_882074.1 118465674 4525732 complement(2918668..2919147) 1 NC_008595.1 identified by match to protein family HMM PF00498; forkhead-associated protein 2919147 4525732 MAV_2888 Mycobacterium avium 104 forkhead-associated protein YP_882074.1 2918668 R 243243 CDS YP_882075.1 118464885 4529614 complement(2919458..2919856) 1 NC_008595.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2919856 gcvH 4529614 gcvH Mycobacterium avium 104 glycine cleavage system protein H YP_882075.1 2919458 R 243243 CDS YP_882076.1 118464174 4526484 complement(2919883..2920722) 1 NC_008595.1 identified by match to protein family HMM PF05949; hypothetical protein 2920722 4526484 MAV_2890 Mycobacterium avium 104 hypothetical protein YP_882076.1 2919883 R 243243 CDS YP_882077.1 118464105 4525866 complement(2920724..2921056) 1 NC_008595.1 identified by match to protein family HMM PF06947; integral membrane protein 2921056 4525866 MAV_2891 Mycobacterium avium 104 integral membrane protein YP_882077.1 2920724 R 243243 CDS YP_882078.1 118463291 4525985 complement(2921118..2922044) 1 NC_008595.1 identified by match to protein family HMM PF05949; hypothetical protein 2922044 4525985 MAV_2892 Mycobacterium avium 104 hypothetical protein YP_882078.1 2921118 R 243243 CDS YP_882079.1 118462588 4530209 complement(2922037..2922666) 1 NC_008595.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 2922666 4530209 MAV_2893 Mycobacterium avium 104 CDP-alcohol phosphatidyltransferase YP_882079.1 2922037 R 243243 CDS YP_882080.1 118463295 4525990 complement(2922721..2925054) 1 NC_008595.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 2925054 4525990 MAV_2894 Mycobacterium avium 104 preprotein translocase subunit SecA YP_882080.1 2922721 R 243243 CDS YP_882081.1 118462562 4528621 complement(2925107..2926753) 1 NC_008595.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; hypothetical protein 2926753 4528621 MAV_2895 Mycobacterium avium 104 hypothetical protein YP_882081.1 2925107 R 243243 CDS YP_882082.1 118465621 4528737 2926844..2928763 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF06472; SbmA protein 2928763 4528737 MAV_2896 Mycobacterium avium 104 SbmA protein YP_882082.1 2926844 D 243243 CDS YP_882083.1 118463573 4530728 complement(2928828..2930321) 1 NC_008595.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; hypothetical protein 2930321 4530728 MAV_2897 Mycobacterium avium 104 hypothetical protein YP_882083.1 2928828 R 243243 CDS YP_882084.1 118462640 4529380 complement(2930371..2930859) 1 NC_008595.1 hypothetical protein 2930859 4529380 MAV_2898 Mycobacterium avium 104 hypothetical protein YP_882084.1 2930371 R 243243 CDS YP_882085.1 118466308 4528350 complement(2931013..2931696) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2931696 4528350 MAV_2899 Mycobacterium avium 104 TetR family transcriptional regulator YP_882085.1 2931013 R 243243 CDS YP_882086.1 118467023 4526535 2931821..2932267 1 NC_008595.1 identified by match to protein family HMM TIGR00026; hypothetical protein 2932267 4526535 MAV_2900 Mycobacterium avium 104 hypothetical protein YP_882086.1 2931821 D 243243 CDS YP_882087.1 118466277 4527829 complement(2932285..2932959) 1 NC_008595.1 hypothetical protein 2932959 4527829 MAV_2901 Mycobacterium avium 104 hypothetical protein YP_882087.1 2932285 R 243243 CDS YP_882088.1 118466987 4529514 complement(2933058..2933984) 1 NC_008595.1 C-5 sterol desaturase 2933984 4529514 MAV_2902 Mycobacterium avium 104 C-5 sterol desaturase YP_882088.1 2933058 R 243243 CDS YP_882089.1 118464815 4527634 complement(2934016..2934735) 1 NC_008595.1 identified by match to protein family HMM PF02308; Mg2+ transporter-C (MgtC) family protein 2934735 4527634 MAV_2903 Mycobacterium avium 104 Mg2+ transporter-C (MgtC) family protein YP_882089.1 2934016 R 243243 CDS YP_882090.1 118465508 4526805 complement(2934861..2935172) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 2935172 4526805 MAV_2904 Mycobacterium avium 104 hypothetical protein YP_882090.1 2934861 R 243243 CDS YP_882091.1 118462708 4530081 complement(2935178..2936563) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2936563 4530081 MAV_2905 Mycobacterium avium 104 PPE family protein YP_882091.1 2935178 R 243243 CDS YP_882092.1 118462945 4530230 complement(2936601..2937845) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2937845 4530230 MAV_2906 Mycobacterium avium 104 PPE family protein YP_882092.1 2936601 R 243243 CDS YP_882093.1 118463814 4526070 complement(2938141..2938449) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 2938449 4526070 MAV_2907 Mycobacterium avium 104 hypothetical protein YP_882093.1 2938141 R 243243 CDS YP_882094.1 118464367 4530510 complement(2938539..2938877) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 2938877 4530510 MAV_2908 Mycobacterium avium 104 hypothetical protein YP_882094.1 2938539 R 243243 CDS YP_882095.1 118465656 4526728 complement(2938912..2940315) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2940315 4526728 MAV_2909 Mycobacterium avium 104 PPE family protein YP_882095.1 2938912 R 243243 CDS YP_882096.1 118465870 4527512 complement(2940393..2941652) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2941652 4527512 MAV_2910 Mycobacterium avium 104 PPE family protein YP_882096.1 2940393 R 243243 CDS YP_882097.1 118466443 4527116 complement(2942538..2943812) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 2943812 4527116 MAV_2911 Mycobacterium avium 104 transposase, Mutator family protein YP_882097.1 2942538 R 243243 CDS YP_882098.1 118467287 4527245 complement(2944028..2944363) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 2944363 4527245 MAV_2912 Mycobacterium avium 104 hypothetical protein YP_882098.1 2944028 R 243243 CDS YP_882099.1 118464522 4529442 complement(2944381..2945595) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2945595 4529442 MAV_2913 Mycobacterium avium 104 PPE family protein YP_882099.1 2944381 R 243243 CDS YP_882100.1 118465439 4527308 complement(2945615..2946745) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2946745 4527308 MAV_2914 Mycobacterium avium 104 PPE family protein YP_882100.1 2945615 R 243243 CDS YP_882101.1 118465345 4526658 complement(2946764..2947063) 1 NC_008595.1 identified by match to protein family HMM PF00934; PE family protein 2947063 4526658 MAV_2915 Mycobacterium avium 104 PE family protein YP_882101.1 2946764 R 243243 CDS YP_882102.1 118464185 4529296 complement(2947613..2949403) 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07719; ATPase AAA 2949403 4529296 MAV_2916 Mycobacterium avium 104 ATPase AAA YP_882102.1 2947613 R 243243 CDS YP_882103.1 118465331 4526527 complement(2949442..2950650) 1 NC_008595.1 hypothetical protein 2950650 4526527 MAV_2917 Mycobacterium avium 104 hypothetical protein YP_882103.1 2949442 R 243243 CDS YP_882104.1 118465602 4527861 complement(2950670..2952499) 1 NC_008595.1 identified by match to protein family HMM PF00082; subtilase 2952499 4527861 MAV_2918 Mycobacterium avium 104 subtilase YP_882104.1 2950670 R 243243 CDS YP_882105.1 118466119 4529752 complement(2952477..2953988) 1 NC_008595.1 identified by match to protein family HMM PF04600; match to protein family HMM TIGR02958; secretion protein Snm4 2953988 snm 4529752 snm Mycobacterium avium 104 secretion protein Snm4 YP_882105.1 2952477 R 243243 CDS YP_882106.1 118462612 4528516 complement(2954249..2955151) 1 NC_008595.1 hypothetical protein 2955151 4528516 MAV_2920 Mycobacterium avium 104 hypothetical protein YP_882106.1 2954249 R 243243 CDS YP_882107.1 118463289 4530537 complement(2955260..2955544) 1 NC_008595.1 identified by match to protein family HMM PF06359; hypothetical protein 2955544 4530537 MAV_2921 Mycobacterium avium 104 hypothetical protein YP_882107.1 2955260 R 243243 CDS YP_882108.1 118464008 4529270 complement(2955587..2955883) 1 NC_008595.1 identified by match to protein family HMM PF06013; hypothetical protein 2955883 4529270 MAV_2922 Mycobacterium avium 104 hypothetical protein YP_882108.1 2955587 R 243243 CDS YP_882109.1 118464018 4528814 complement(2956141..2956326) 1 NC_008595.1 identified by match to protein family HMM PF00934; Excalibur protein 2956326 4528814 MAV_2923 Mycobacterium avium 104 Excalibur protein YP_882109.1 2956141 R 243243 CDS YP_882110.1 118466367 4529929 complement(2956837..2958054) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2958054 4529929 MAV_2924 Mycobacterium avium 104 PPE family protein YP_882110.1 2956837 R 243243 CDS YP_882111.1 118466905 4528419 complement(2958388..2959605) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2959605 4528419 MAV_2925 Mycobacterium avium 104 PPE family protein YP_882111.1 2958388 R 243243 CDS YP_882112.1 118464959 4528699 complement(2960169..2961392) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2961392 4528699 MAV_2926 Mycobacterium avium 104 PPE family protein YP_882112.1 2960169 R 243243 CDS YP_882113.1 118467001 4529471 complement(2961400..2961531) 1 NC_008595.1 hypothetical protein 2961531 4529471 MAV_2927 Mycobacterium avium 104 hypothetical protein YP_882113.1 2961400 R 243243 CDS YP_882114.1 118464876 4530712 complement(2961618..2962883) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 2962883 4530712 MAV_2928 Mycobacterium avium 104 PPE family protein YP_882114.1 2961618 R 243243 CDS YP_882115.1 118462574 4528633 complement(2963362..2963526) 1 NC_008595.1 hypothetical protein 2963526 4528633 MAV_2929 Mycobacterium avium 104 hypothetical protein YP_882115.1 2963362 R 243243 CDS YP_882116.1 118463024 4526317 2963662..2963811 1 NC_008595.1 hypothetical protein 2963811 4526317 MAV_2930 Mycobacterium avium 104 hypothetical protein YP_882116.1 2963662 D 243243 CDS YP_882117.1 118465559 4525809 2963828..2964991 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 2964991 4525809 MAV_2931 Mycobacterium avium 104 P450 heme-thiolate protein YP_882117.1 2963828 D 243243 CDS YP_882118.1 118464740 4529427 complement(2965034..2969161) 1 NC_008595.1 identified by match to protein family HMM PF01580; ftsk/SpoIIIE family protein 2969161 4529427 MAV_2932 Mycobacterium avium 104 ftsk/SpoIIIE family protein YP_882118.1 2965034 R 243243 CDS YP_882119.1 118462835 4528650 complement(2969200..2970717) 1 NC_008595.1 identified by match to protein family HMM PF05108; hypothetical protein 2970717 4528650 MAV_2933 Mycobacterium avium 104 hypothetical protein YP_882119.1 2969200 R 243243 CDS YP_882120.1 118463263 4528128 2971114..2973285 1 NC_008595.1 identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217; 4-alpha-glucanotransferase 2973285 malQ 4528128 malQ Mycobacterium avium 104 4-alpha-glucanotransferase YP_882120.1 2971114 D 243243 CDS YP_882121.1 118466263 4526882 2973326..2974204 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 2974204 4526882 MAV_2935 Mycobacterium avium 104 hypothetical protein YP_882121.1 2973326 D 243243 CDS YP_882122.1 118464726 4529413 2974201..2974671 1 NC_008595.1 hypothetical protein 2974671 4529413 MAV_2936 Mycobacterium avium 104 hypothetical protein YP_882122.1 2974201 D 243243 CDS YP_882123.1 118462690 4526670 2975018..2976760 1 NC_008595.1 identified by match to protein family HMM PF00174; oxidoreductase molybdopterin binding subunit 2976760 4526670 MAV_2937 Mycobacterium avium 104 oxidoreductase molybdopterin binding subunit YP_882123.1 2975018 D 243243 CDS YP_882124.1 118466625 4526863 2976888..2977163 1 NC_008595.1 hypothetical protein 2977163 4526863 MAV_2939 Mycobacterium avium 104 hypothetical protein YP_882124.1 2976888 D 243243 CDS YP_882125.1 118467209 4529590 complement(2977144..2977584) 1 NC_008595.1 hypothetical protein 2977584 4529590 MAV_2938 Mycobacterium avium 104 hypothetical protein YP_882125.1 2977144 R 243243 CDS YP_882126.1 118465449 4527318 complement(2977673..2978233) 1 NC_008595.1 hypothetical protein 2978233 4527318 MAV_2940 Mycobacterium avium 104 hypothetical protein YP_882126.1 2977673 R 243243 CDS YP_882127.1 118465300 4526554 complement(2978253..2978474) 1 NC_008595.1 hypothetical protein 2978474 4526554 MAV_2941 Mycobacterium avium 104 hypothetical protein YP_882127.1 2978253 R 243243 CDS YP_882128.1 118464920 4528560 2978517..2980313 1 NC_008595.1 hypothetical protein 2980313 4528560 MAV_2942 Mycobacterium avium 104 hypothetical protein YP_882128.1 2978517 D 243243 CDS YP_882129.1 118467318 4530311 complement(2980345..2980551) 1 NC_008595.1 hypothetical protein 2980551 4530311 MAV_2943 Mycobacterium avium 104 hypothetical protein YP_882129.1 2980345 R 243243 CDS YP_882130.1 118464469 4527062 complement(2980548..2980835) 1 NC_008595.1 identified by match to protein family HMM PF03861; ANTAR domain-containing protein 2980835 4527062 MAV_2944 Mycobacterium avium 104 ANTAR domain-containing protein YP_882130.1 2980548 R 243243 CDS YP_882131.1 118464520 4529440 complement(2981123..2982322) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 2982322 4529440 MAV_2945 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_882131.1 2981123 R 243243 CDS YP_882132.1 118463927 4528107 2982618..2983490 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 2983490 4528107 MAV_2946 Mycobacterium avium 104 carveol dehydrogenase YP_882132.1 2982618 D 243243 CDS YP_882133.1 118467045 4526501 2983495..2984487 1 NC_008595.1 identified by match to protein family HMM PF00676; dehydrogenase E1 component superfamily protein 2984487 4526501 MAV_2947 Mycobacterium avium 104 dehydrogenase E1 component superfamily protein YP_882133.1 2983495 D 243243 CDS YP_882134.1 118466552 4529101 2984499..2985509 1 NC_008595.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit 2985509 4529101 MAV_2948 Mycobacterium avium 104 acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit YP_882134.1 2984499 D 243243 CDS YP_882135.1 118465521 4528938 2985502..2985738 1 NC_008595.1 identified by match to protein family HMM PF00364; dihydrolipoamide acetyltransferase 2985738 4528938 MAV_2949 Mycobacterium avium 104 dihydrolipoamide acetyltransferase YP_882135.1 2985502 D 243243 CDS YP_882136.1 118462578 4530198 2985790..2986662 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2986662 4530198 MAV_2950 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_882136.1 2985790 D 243243 CDS YP_882137.1 118467324 4526962 2986672..2988195 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 2988195 4526962 MAV_2951 Mycobacterium avium 104 acyl-CoA synthase YP_882137.1 2986672 D 243243 CDS YP_882138.1 118463093 4528916 2988247..2989599 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 2989599 4528916 MAV_2952 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_882138.1 2988247 D 243243 CDS YP_882139.1 118463317 4529557 2989602..2991341 1 NC_008595.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 2991341 4529557 MAV_2953 Mycobacterium avium 104 3-ketosteroid-delta-1-dehydrogenase YP_882139.1 2989602 D 243243 CDS YP_882140.1 118464380 4528269 complement(2991374..2992279) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 2992279 4528269 MAV_2954 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_882140.1 2991374 R 243243 CDS YP_882141.1 118464203 4529314 complement(2992335..2992586) 1 NC_008595.1 hypothetical protein 2992586 4529314 MAV_2955 Mycobacterium avium 104 hypothetical protein YP_882141.1 2992335 R 243243 CDS YP_882142.1 118463537 4526843 2992593..2993960 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 2993960 4526843 MAV_2956 Mycobacterium avium 104 ATP-dependent RNA helicase YP_882142.1 2992593 D 243243 CDS YP_882143.1 118465770 4526905 complement(2993969..2994544) 1 NC_008595.1 identified by match to protein family HMM PF05724; thiopurine S-methyltransferase 2994544 4526905 MAV_2957 Mycobacterium avium 104 thiopurine S-methyltransferase YP_882143.1 2993969 R 243243 CDS YP_882144.1 118462748 4527838 2994641..2995246 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2995246 4527838 MAV_2958 Mycobacterium avium 104 TetR family transcriptional regulator YP_882144.1 2994641 D 243243 CDS YP_882145.1 118466719 4530657 complement(2995283..2997049) 1 NC_008595.1 N-acyl-D-glutamate amidohydrolase 2997049 4530657 MAV_2959 Mycobacterium avium 104 N-acyl-D-glutamate amidohydrolase YP_882145.1 2995283 R 243243 CDS YP_882146.1 118465590 4527138 2997234..2997908 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2997908 4527138 MAV_2960 Mycobacterium avium 104 TetR family transcriptional regulator YP_882146.1 2997234 D 243243 CDS YP_882147.1 118464918 4528558 2998113..2998760 1 NC_008595.1 identified by match to protein family HMM PF01083; cutinase Cut3 2998760 4528558 MAV_2961 Mycobacterium avium 104 cutinase Cut3 YP_882147.1 2998113 D 243243 CDS YP_882148.1 118464086 4528399 complement(2998794..2999693) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 2999693 4528399 MAV_2962 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_882148.1 2998794 R 243243 CDS YP_882149.1 118465934 4528493 3000423..3001232 1 NC_008595.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock; RNA polymerase sigma factor SigF 3001232 4528493 MAV_2963 Mycobacterium avium 104 RNA polymerase sigma factor SigF YP_882149.1 3000423 D 243243 CDS YP_882150.1 118462458 4525631 3001377..3001994 1 NC_008595.1 hypothetical protein 3001994 4525631 MAV_2964 Mycobacterium avium 104 hypothetical protein YP_882150.1 3001377 D 243243 CDS YP_882151.1 118464659 4528256 3002020..3002511 1 NC_008595.1 hypothetical protein 3002511 4528256 MAV_2965 Mycobacterium avium 104 hypothetical protein YP_882151.1 3002020 D 243243 CDS YP_882152.1 118466094 4527723 complement(3002523..3002999) 1 NC_008595.1 identified by match to protein family HMM TIGR00026; hypothetical protein 3002999 4527723 MAV_2966 Mycobacterium avium 104 hypothetical protein YP_882152.1 3002523 R 243243 CDS YP_882153.1 118462948 4530233 3003184..3003918 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3003918 4530233 MAV_2967 Mycobacterium avium 104 TetR family transcriptional regulator YP_882153.1 3003184 D 243243 CDS YP_882154.1 118465933 4528492 3003915..3005144 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450-SU2 3005144 4528492 MAV_2968 Mycobacterium avium 104 cytochrome P450-SU2 YP_882154.1 3003915 D 243243 CDS YP_882155.1 118466655 4528094 3005141..3006085 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 3006085 4528094 MAV_2969 Mycobacterium avium 104 short chain dehydrogenase YP_882155.1 3005141 D 243243 CDS YP_882156.1 118465325 4526521 3006156..3007385 1 NC_008595.1 identified by match to protein family HMM PF00557; peptidase, M24 family protein 3007385 4526521 MAV_2970 Mycobacterium avium 104 peptidase, M24 family protein YP_882156.1 3006156 D 243243 CDS YP_882157.1 118466033 4529920 3007375..3008505 1 NC_008595.1 identified by match to protein family HMM PF00557; peptidase, M24 family protein 3008505 4529920 MAV_2971 Mycobacterium avium 104 peptidase, M24 family protein YP_882157.1 3007375 D 243243 CDS YP_882158.1 118463582 4529767 3008581..3009012 1 NC_008595.1 REPhypothetical protein 3009012 4529767 MAV_2972 Mycobacterium avium 104 REPhypothetical protein YP_882158.1 3008581 D 243243 CDS YP_882159.1 118463153 4527791 3009094..3010038 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3010038 4527791 MAV_2974 Mycobacterium avium 104 transposase, Mutator family protein YP_882159.1 3009094 D 243243 CDS YP_882160.1 118464275 4528230 complement(3009975..3011249) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3011249 4528230 MAV_2973 Mycobacterium avium 104 transposase, Mutator family protein YP_882160.1 3009975 R 243243 CDS YP_882161.1 118463560 4530715 3011335..3011787 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3011787 4530715 MAV_2975 Mycobacterium avium 104 transposase, Mutator family protein YP_882161.1 3011335 D 243243 CDS YP_882162.1 118466417 4530161 3011899..3013173 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3013173 4530161 MAV_2976 Mycobacterium avium 104 transposase, Mutator family protein YP_882162.1 3011899 D 243243 CDS YP_882163.1 118466780 4529338 3013233..3014222 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 3014222 4529338 MAV_2977 Mycobacterium avium 104 hypothetical protein YP_882163.1 3013233 D 243243 CDS YP_882164.1 118462869 4527097 complement(3014264..3014446) 1 NC_008595.1 identified by match to protein family HMM PF05901; Excalibur domain-containing protein 3014446 4527097 MAV_2978 Mycobacterium avium 104 Excalibur domain-containing protein YP_882164.1 3014264 R 243243 CDS YP_882165.1 118462812 4529032 complement(3014560..3015831) 1 NC_008595.1 hypothetical protein 3015831 4529032 MAV_2979 Mycobacterium avium 104 hypothetical protein YP_882165.1 3014560 R 243243 CDS YP_882166.1 118464582 4530286 complement(3015851..3016612) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; clavaldehyde dehydrogenase 3016612 4530286 MAV_2980 Mycobacterium avium 104 clavaldehyde dehydrogenase YP_882166.1 3015851 R 243243 CDS YP_882167.1 118463998 4529260 complement(3016609..3018981) 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 3018981 4529260 MAV_2981 Mycobacterium avium 104 caib/baif family protein YP_882167.1 3016609 R 243243 CDS YP_882168.1 118465248 4528466 complement(3019001..3019969) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 3019969 4528466 MAV_2982 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_882168.1 3019001 R 243243 CDS YP_882169.1 118465018 4530067 complement(3020006..3020866) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 3020866 4530067 MAV_2983 Mycobacterium avium 104 carveol dehydrogenase YP_882169.1 3020006 R 243243 CDS YP_882170.1 118466989 4529516 complement(3020842..3022044) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 3022044 4529516 MAV_2984 Mycobacterium avium 104 cytochrome P450 YP_882170.1 3020842 R 243243 CDS YP_882171.1 118466191 4530181 complement(3022268..3022942) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3022942 4530181 MAV_2985 Mycobacterium avium 104 TetR family transcriptional regulator YP_882171.1 3022268 R 243243 CDS YP_882172.1 118462325 4529643 3023077..3023685 1 NC_008595.1 protein export protein SecD, putative 3023685 4529643 MAV_2986 Mycobacterium avium 104 protein export protein SecD, putative YP_882172.1 3023077 D 243243 CDS YP_882173.1 118465969 4528188 complement(3023720..3024730) 1 NC_008595.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; NAD binding oxidoreductase 3024730 4528188 MAV_2987 Mycobacterium avium 104 NAD binding oxidoreductase YP_882173.1 3023720 R 243243 CDS YP_882174.1 118464124 4526295 3024864..3025529 1 NC_008595.1 identified by match to protein family HMM PF01209; ubiquinone/menaquinone biosynthesis methyltransferases 3025529 4526295 MAV_2988 Mycobacterium avium 104 ubiquinone/menaquinone biosynthesis methyltransferases YP_882174.1 3024864 D 243243 CDS YP_882175.1 118465366 4529227 complement(3025550..3027151) 1 NC_008595.1 identified by match to protein family HMM PF00884; arylsulfatase 3027151 4529227 MAV_2989 Mycobacterium avium 104 arylsulfatase YP_882175.1 3025550 R 243243 CDS YP_882176.1 118465761 4530454 3027258..3028277 1 NC_008595.1 identified by match to protein family HMM PF03060; oxidoreductase 3028277 4530454 MAV_2990 Mycobacterium avium 104 oxidoreductase YP_882176.1 3027258 D 243243 CDS YP_882177.1 118466462 4528683 complement(3028282..3029103) 1 NC_008595.1 identified by match to protein family HMM PF02409; tetracenomycin polyketide synthesis O-methyltransferase TcmP 3029103 4528683 MAV_2991 Mycobacterium avium 104 tetracenomycin polyketide synthesis O-methyltransferase TcmP YP_882177.1 3028282 R 243243 CDS YP_882178.1 118466247 4526866 complement(3029100..3029627) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3029627 4526866 MAV_2992 Mycobacterium avium 104 MarR family transcriptional regulator YP_882178.1 3029100 R 243243 CDS YP_882179.1 118462436 4528299 complement(3029718..3030986) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 3030986 4528299 MAV_2993 Mycobacterium avium 104 amidohydrolase YP_882179.1 3029718 R 243243 CDS YP_882180.1 118463141 4527779 complement(3031117..3031890) 1 NC_008595.1 identified by match to protein family HMM PF00596; class II aldolase 3031890 4527779 MAV_2994 Mycobacterium avium 104 class II aldolase YP_882180.1 3031117 R 243243 CDS YP_882181.1 118463544 4526811 complement(3031877..3033505) 1 NC_008595.1 identified by match to protein family HMM PF00501; adenylate-forming enzyme 3033505 4526811 MAV_2995 Mycobacterium avium 104 adenylate-forming enzyme YP_882181.1 3031877 R 243243 CDS YP_882182.1 118462328 4525673 complement(3033569..3034087) 1 NC_008595.1 lipoprotein 3034087 4525673 MAV_2996 Mycobacterium avium 104 lipoprotein YP_882182.1 3033569 R 243243 CDS YP_882183.1 118464271 4528226 complement(3034080..3035357) 1 NC_008595.1 identified by match to protein family HMM PF00174; oxidoreductase, molybdopterin binding 3035357 4528226 MAV_2997 Mycobacterium avium 104 oxidoreductase, molybdopterin binding YP_882183.1 3034080 R 243243 CDS YP_882184.1 118464337 4529139 3035367..3035483 1 NC_008595.1 hypothetical protein 3035483 4529139 MAV_2998 Mycobacterium avium 104 hypothetical protein YP_882184.1 3035367 D 243243 CDS YP_882185.1 118465560 4525810 3035583..3036980 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 3036980 4525810 MAV_2999 Mycobacterium avium 104 hypothetical protein YP_882185.1 3035583 D 243243 CDS YP_882186.1 118464873 4530709 complement(3036983..3038602) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3038602 4530709 MAV_3000 Mycobacterium avium 104 acyl-CoA synthetase YP_882186.1 3036983 R 243243 CDS YP_882187.1 118466424 4530168 complement(3038599..3040194) 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF07992; steroid monooxygenase 3040194 4530168 MAV_3001 Mycobacterium avium 104 steroid monooxygenase YP_882187.1 3038599 R 243243 CDS YP_882188.1 118466332 4528763 complement(3040191..3040364) 1 NC_008595.1 hypothetical protein 3040364 4528763 MAV_3002 Mycobacterium avium 104 hypothetical protein YP_882188.1 3040191 R 243243 CDS YP_882189.1 118462764 4527855 complement(3040361..3040762) 1 NC_008595.1 identified by match to protein family HMM PF01796; acyl dehydratase 3040762 4527855 MAV_3003 Mycobacterium avium 104 acyl dehydratase YP_882189.1 3040361 R 243243 CDS YP_882190.1 118463190 4527713 complement(3040765..3041967) 1 NC_008595.1 nonspecific lipid-transfer protein 3041967 4527713 MAV_3004 Mycobacterium avium 104 nonspecific lipid-transfer protein YP_882190.1 3040765 R 243243 CDS YP_882191.1 118466389 4526190 complement(3041964..3042401) 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC like domain-containing protein 3042401 4526190 MAV_3005 Mycobacterium avium 104 MaoC like domain-containing protein YP_882191.1 3041964 R 243243 CDS YP_882192.1 118467174 4530144 complement(3042428..3042913) 1 NC_008595.1 hypothetical protein 3042913 4530144 MAV_3006 Mycobacterium avium 104 hypothetical protein YP_882192.1 3042428 R 243243 CDS YP_882193.1 118463536 4526842 complement(3042921..3044057) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 3044057 4526842 MAV_3007 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_882193.1 3042921 R 243243 CDS YP_882194.1 118463454 4529696 complement(3044077..3045255) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 3045255 4529696 MAV_3008 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882194.1 3044077 R 243243 CDS YP_882195.1 118465814 4525917 3045571..3045735 1 NC_008595.1 hypothetical protein 3045735 4525917 MAV_3009 Mycobacterium avium 104 hypothetical protein YP_882195.1 3045571 D 243243 CDS YP_882196.1 118465124 4530477 complement(3045740..3048328) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061; ABC transporter ATP-binding protein 3048328 4530477 MAV_3010 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882196.1 3045740 R 243243 CDS YP_882197.1 118463894 4530571 complement(3048527..3049528) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 3049528 4530571 MAV_3011 Mycobacterium avium 104 alpha/beta hydrolase YP_882197.1 3048527 R 243243 CDS YP_882198.1 118464634 4528969 3049775..3050620 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 3050620 4528969 MAV_3012 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_882198.1 3049775 D 243243 CDS YP_882199.1 118464112 4526283 complement(3050718..3050951) 1 NC_008595.1 hypothetical protein 3050951 4526283 MAV_3013 Mycobacterium avium 104 hypothetical protein YP_882199.1 3050718 R 243243 CDS YP_882200.1 118463494 4529073 3051200..3051634 1 NC_008595.1 hypothetical protein 3051634 4529073 MAV_3014 Mycobacterium avium 104 hypothetical protein YP_882200.1 3051200 D 243243 CDS YP_882201.1 118462765 4527262 3051857..3053218 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 3053218 4527262 MAV_3015 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_882201.1 3051857 D 243243 CDS YP_882202.1 118466720 4530658 3053286..3054179 1 NC_008595.1 identified by match to protein family HMM PF00561; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3054179 4530658 MAV_3016 Mycobacterium avium 104 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase YP_882202.1 3053286 D 243243 CDS YP_882203.1 118466347 4530487 complement(3054231..3055034) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 3055034 4530487 MAV_3017 Mycobacterium avium 104 carveol dehydrogenase YP_882203.1 3054231 R 243243 CDS YP_882204.1 118465646 4526171 3055211..3056836 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF05834; match to protein family HMM PF07992; steroid monooxygenase 3056836 4526171 MAV_3018 Mycobacterium avium 104 steroid monooxygenase YP_882204.1 3055211 D 243243 CDS YP_882205.1 118465102 4529993 3056836..3057642 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; carveol dehydrogenase 3057642 4529993 MAV_3019 Mycobacterium avium 104 carveol dehydrogenase YP_882205.1 3056836 D 243243 CDS YP_882206.1 118463900 4530577 3057769..3058953 1 NC_008595.1 identified by match to protein family HMM PF08028; pigment production hydroxylase 3058953 4530577 MAV_3020 Mycobacterium avium 104 pigment production hydroxylase YP_882206.1 3057769 D 243243 CDS YP_882207.1 118465888 4527922 3058964..3059872 1 NC_008595.1 identified by match to protein family HMM PF00903; biphenyl-2,3-diol 1,2-dioxygenase 1 3059872 4527922 MAV_3021 Mycobacterium avium 104 biphenyl-2,3-diol 1,2-dioxygenase 1 YP_882207.1 3058964 D 243243 CDS YP_882208.1 118464780 4529135 3059869..3061344 1 NC_008595.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; hypothetical protein 3061344 4529135 MAV_3022 Mycobacterium avium 104 hypothetical protein YP_882208.1 3059869 D 243243 CDS YP_882209.1 118464498 4525541 3061323..3061460 1 NC_008595.1 hypothetical protein 3061460 4525541 MAV_3023 Mycobacterium avium 104 hypothetical protein YP_882209.1 3061323 D 243243 CDS YP_882210.1 118464416 4530237 3061487..3062323 1 NC_008595.1 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 3062323 4530237 MAV_3024 Mycobacterium avium 104 IclR family transcriptional regulator YP_882210.1 3061487 D 243243 CDS YP_882211.1 118463675 4528520 3062320..3063243 1 NC_008595.1 identified by match to protein family HMM PF07859; esterase 3063243 4528520 MAV_3025 Mycobacterium avium 104 esterase YP_882211.1 3062320 D 243243 CDS YP_882212.1 118466807 4529054 3063329..3063685 1 NC_008595.1 hypothetical protein 3063685 4529054 MAV_3026 Mycobacterium avium 104 hypothetical protein YP_882212.1 3063329 D 243243 CDS YP_882213.1 118466681 4530423 3063678..3064304 1 NC_008595.1 identified by match to protein family HMM PF07876; stress responsive A/B barrel domain family protein 3064304 4530423 MAV_3028 Mycobacterium avium 104 stress responsive A/B barrel domain family protein YP_882213.1 3063678 D 243243 CDS YP_882214.1 118463392 4528019 complement(3064301..3065188) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 3065188 4528019 MAV_3027 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_882214.1 3064301 R 243243 CDS YP_882215.1 118462697 4526677 complement(3065185..3067113) 1 NC_008595.1 hypothetical protein 3067113 4526677 MAV_3029 Mycobacterium avium 104 hypothetical protein YP_882215.1 3065185 R 243243 CDS YP_882216.1 118462590 4530211 3067333..3067812 1 NC_008595.1 hypothetical protein 3067812 4530211 MAV_3030 Mycobacterium avium 104 hypothetical protein YP_882216.1 3067333 D 243243 CDS YP_882217.1 118467117 4526143 3067851..3068684 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 3068684 4526143 MAV_3031 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_882217.1 3067851 D 243243 CDS YP_882218.1 118463484 4529062 3068691..3069674 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 3069674 4529062 MAV_3032 Mycobacterium avium 104 alpha/beta hydrolase YP_882218.1 3068691 D 243243 CDS YP_882219.1 118463863 4527741 3069719..3070795 1 NC_008595.1 hypothetical protein 3070795 4527741 MAV_3033 Mycobacterium avium 104 hypothetical protein YP_882219.1 3069719 D 243243 CDS YP_882220.1 118464308 4526638 3070816..3071598 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF07993; oxidoreductase 3071598 4526638 MAV_3034 Mycobacterium avium 104 oxidoreductase YP_882220.1 3070816 D 243243 CDS YP_882221.1 118465317 4526571 complement(3071705..3072493) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase SDR 3072493 4526571 MAV_3035 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_882221.1 3071705 R 243243 CDS YP_882222.1 118464064 4529504 complement(3072526..3072795) 1 NC_008595.1 hypothetical protein 3072795 4529504 MAV_3036 Mycobacterium avium 104 hypothetical protein YP_882222.1 3072526 R 243243 CDS YP_882223.1 118464956 4528696 complement(3072813..3073925) 1 NC_008595.1 identified by match to protein family HMM PF00355; oxygenase KshA 3073925 4528696 MAV_3037 Mycobacterium avium 104 oxygenase KshA YP_882223.1 3072813 R 243243 CDS YP_882224.1 118465515 4528932 complement(3073996..3075321) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3075321 4528932 MAV_3038 Mycobacterium avium 104 transposase, Mutator family protein YP_882224.1 3073996 R 243243 CDS YP_882225.1 118466296 4529543 3075452..3077197 1 NC_008595.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 3077197 4529543 MAV_3039 Mycobacterium avium 104 3-ketosteroid-delta-1-dehydrogenase YP_882225.1 3075452 D 243243 CDS YP_882226.1 118466974 4530373 complement(3077414..3077716) 1 NC_008595.1 hypothetical protein 3077716 4530373 MAV_3040 Mycobacterium avium 104 hypothetical protein YP_882226.1 3077414 R 243243 CDS YP_882227.1 118463505 4527685 3077738..3077941 1 NC_008595.1 hypothetical protein 3077941 4527685 MAV_3041 Mycobacterium avium 104 hypothetical protein YP_882227.1 3077738 D 243243 CDS YP_882228.1 118464010 4529272 3078143..3078904 1 NC_008595.1 hypothetical protein 3078904 4529272 MAV_3042 Mycobacterium avium 104 hypothetical protein YP_882228.1 3078143 D 243243 CDS YP_882229.1 118466658 4528097 complement(3079057..3080400) 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 3080400 4528097 MAV_3043 Mycobacterium avium 104 hypothetical protein YP_882229.1 3079057 R 243243 CDS YP_882230.1 118466017 4529903 complement(3080533..3081213) 1 NC_008595.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 3081213 4529903 MAV_3044 Mycobacterium avium 104 PadR family transcriptional regulator YP_882230.1 3080533 R 243243 CDS YP_882231.1 118463868 4527746 3081275..3082195 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 3082195 4527746 MAV_3045 Mycobacterium avium 104 hypothetical protein YP_882231.1 3081275 D 243243 CDS YP_882232.1 118464246 4527431 complement(3082197..3083072) 1 NC_008595.1 hypothetical protein 3083072 4527431 MAV_3046 Mycobacterium avium 104 hypothetical protein YP_882232.1 3082197 R 243243 CDS YP_882233.1 118462771 4527268 3083139..3084290 1 NC_008595.1 identified by match to protein family HMM PF07992; pyridine nucleotide-disulphide oxidoreductase, putative 3084290 4527268 MAV_3047 Mycobacterium avium 104 pyridine nucleotide-disulphide oxidoreductase, putative YP_882233.1 3083139 D 243243 CDS YP_882234.1 118463102 4528925 complement(3084317..3085765) 1 NC_008595.1 identified by similarity to GB:AAD24211.1; match to protein family HMM PF00394; match to protein family HMM PF07731; match to protein family HMM PF07732; multicopper oxidase 3085765 4528925 MAV_3048 Mycobacterium avium 104 multicopper oxidase YP_882234.1 3084317 R 243243 CDS YP_882235.1 118466348 4530488 3085995..3086492 1 NC_008595.1 identified by match to protein family HMM PF01613; oxidoreductase 3086492 4530488 MAV_3049 Mycobacterium avium 104 oxidoreductase YP_882235.1 3085995 D 243243 CDS YP_882236.1 118466407 4526250 3086495..3087205 1 NC_008595.1 identified by match to protein family HMM PF01872; hypothetical protein 3087205 4526250 MAV_3050 Mycobacterium avium 104 hypothetical protein YP_882236.1 3086495 D 243243 CDS YP_882237.1 118467141 4527155 3087245..3087712 1 NC_008595.1 hypothetical protein 3087712 4527155 MAV_3051 Mycobacterium avium 104 hypothetical protein YP_882237.1 3087245 D 243243 CDS YP_882238.1 118464354 4529156 complement(3088386..3089876) 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; sugar ABC transporter 3089876 4529156 MAV_3053 Mycobacterium avium 104 sugar ABC transporter YP_882238.1 3088386 R 243243 CDS YP_882239.1 118465361 4529221 complement(3089880..3091673) 1 NC_008595.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR03103; GNAT family acetyltransferase 3091673 4529221 MAV_3054 Mycobacterium avium 104 GNAT family acetyltransferase YP_882239.1 3089880 R 243243 CDS YP_882240.1 118465925 4528484 complement(3091670..3093409) 1 NC_008595.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536; match to protein family HMM TIGR03104; asparagine synthase (glutamine-hydrolyzing) 3093409 asnB 4528484 asnB Mycobacterium avium 104 asparagine synthase (glutamine-hydrolyzing) YP_882240.1 3091670 R 243243 CDS YP_882241.1 118463736 4528144 complement(3093635..3124900) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM PF05175; match to protein family HMM PF05401; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; linear gramicidin synthetase subunit D 3124900 4528144 MAV_3056 Mycobacterium avium 104 linear gramicidin synthetase subunit D YP_882241.1 3093635 R 243243 CDS YP_882242.1 118464196 4529307 complement(3124957..3125175) 1 NC_008595.1 identified by match to protein family HMM PF03621; hypothetical protein 3125175 4529307 MAV_3057 Mycobacterium avium 104 hypothetical protein YP_882242.1 3124957 R 243243 CDS YP_882243.1 118462922 4526013 3125251..3125496 1 NC_008595.1 hypothetical protein 3125496 4526013 MAV_3058 Mycobacterium avium 104 hypothetical protein YP_882243.1 3125251 D 243243 CDS YP_882244.1 118462330 4525675 3126302..3127087 1 NC_008595.1 hypothetical protein 3127087 4525675 MAV_3059 Mycobacterium avium 104 hypothetical protein YP_882244.1 3126302 D 243243 CDS YP_882245.1 118464053 4529493 3127203..3127637 1 NC_008595.1 hypothetical protein 3127637 4529493 MAV_3060 Mycobacterium avium 104 hypothetical protein YP_882245.1 3127203 D 243243 CDS YP_882246.1 118467083 4526383 3127686..3128351 1 NC_008595.1 hypothetical protein 3128351 4526383 MAV_3061 Mycobacterium avium 104 hypothetical protein YP_882246.1 3127686 D 243243 CDS YP_882247.1 118462577 4530197 complement(3128638..3130038) 1 NC_008595.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 3130038 engA 4530197 engA Mycobacterium avium 104 GTP-binding protein EngA YP_882247.1 3128638 R 243243 CDS YP_882248.1 118465941 4527937 complement(3130035..3130721) 1 NC_008595.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 3130721 cmk 4527937 cmk Mycobacterium avium 104 cytidylate kinase YP_882248.1 3130035 R 243243 CDS YP_882249.1 118465035 4525814 complement(3130718..3131464) 1 NC_008595.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 3131464 4525814 MAV_3065 Mycobacterium avium 104 ribosomal large subunit pseudouridine synthase B YP_882249.1 3130718 R 243243 CDS YP_882250.1 118466801 4529047 complement(3131461..3132168) 1 NC_008595.1 identified by match to protein family HMM PF04079; match to protein family HMM TIGR00281; segregation and condensation protein B 3132168 scpB 4529047 scpB Mycobacterium avium 104 segregation and condensation protein B YP_882250.1 3131461 R 243243 CDS YP_882251.1 118466102 4527731 complement(3132165..3132983) 1 NC_008595.1 identified by match to protein family HMM PF02616; segregation and condensation protein A 3132983 scpA 4527731 scpA Mycobacterium avium 104 segregation and condensation protein A YP_882251.1 3132165 R 243243 CDS YP_882252.1 118465630 4528747 complement(3132980..3133843) 1 NC_008595.1 identified by match to protein family HMM PF01656; SpoOJ regulator protein 3133843 soj 4528747 soj Mycobacterium avium 104 SpoOJ regulator protein YP_882252.1 3132980 R 243243 CDS YP_882253.1 118464980 4527472 3134081..3134833 1 NC_008595.1 identified by match to protein family HMM PF01596; catechol-O-methyltransferase 3134833 4527472 MAV_3069 Mycobacterium avium 104 catechol-O-methyltransferase YP_882253.1 3134081 D 243243 CDS YP_882254.1 118464686 4528381 complement(3134859..3135800) 1 NC_008595.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3135800 xerD 4528381 xerD Mycobacterium avium 104 site-specific tyrosine recombinase XerD YP_882254.1 3134859 R 243243 CDS YP_882255.1 118463972 4527219 complement(3135797..3136420) 1 NC_008595.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 3136420 4527219 MAV_3071 Mycobacterium avium 104 MutT/nudix family protein YP_882255.1 3135797 R 243243 CDS YP_882256.1 118462234 4525572 complement(3136413..3138164) 1 NC_008595.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3138164 pyrG 4525572 pyrG Mycobacterium avium 104 CTP synthetase YP_882256.1 3136413 R 243243 CDS YP_882257.1 118462831 4528645 complement(3138287..3139240) 1 NC_008595.1 hypothetical protein 3139240 4528645 MAV_3073 Mycobacterium avium 104 hypothetical protein YP_882257.1 3138287 R 243243 CDS YP_882258.1 118466244 4526590 complement(3139241..3140422) 1 NC_008595.1 hypothetical protein 3140422 4526590 MAV_3074 Mycobacterium avium 104 hypothetical protein YP_882258.1 3139241 R 243243 CDS YP_882259.1 118466477 4527607 complement(3140607..3142376) 1 NC_008595.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 3142376 recN 4527607 recN Mycobacterium avium 104 DNA repair protein RecN YP_882259.1 3140607 R 243243 CDS YP_882260.1 118463788 4525869 complement(3142402..3143328) 1 NC_008595.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3143328 ppnK 4525869 ppnK Mycobacterium avium 104 inorganic polyphosphate/ATP-NAD kinase YP_882260.1 3142402 R 243243 CDS YP_882261.1 118462925 4526016 complement(3143325..3144134) 1 NC_008595.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 3144134 4526016 MAV_3077 Mycobacterium avium 104 hemolysin A YP_882261.1 3143325 R 243243 CDS YP_882262.1 118467047 4526503 complement(3144143..3144328) 1 NC_008595.1 hypothetical protein 3144328 4526503 MAV_3078 Mycobacterium avium 104 hypothetical protein YP_882262.1 3144143 R 243243 CDS YP_882263.1 118466906 4528420 complement(3144352..3145374) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; HAD-superfamily protein hydrolase, subfamily protein IIA 3145374 4528420 MAV_3079 Mycobacterium avium 104 HAD-superfamily protein hydrolase, subfamily protein IIA YP_882263.1 3144352 R 243243 CDS YP_882264.1 118466688 4530430 complement(3145376..3146011) 1 NC_008595.1 TPR repeat-containing protein 3146011 4530430 MAV_3080 Mycobacterium avium 104 TPR repeat-containing protein YP_882264.1 3145376 R 243243 CDS YP_882265.1 118465764 4530457 complement(3146199..3146567) 1 NC_008595.1 identified by match to protein family HMM PF05305; LprJ protein 3146567 4530457 MAV_3081 Mycobacterium avium 104 LprJ protein YP_882265.1 3146199 R 243243 CDS YP_882266.1 118464949 4528211 complement(3146659..3147924) 1 NC_008595.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 3147924 tyrS 4528211 tyrS Mycobacterium avium 104 tyrosyl-tRNA synthetase YP_882266.1 3146659 R 243243 CDS YP_882267.1 118464671 4528366 complement(3147936..3148574) 1 NC_008595.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 3148574 4528366 MAV_3083 Mycobacterium avium 104 3-methyladenine DNA glycosylase YP_882267.1 3147936 R 243243 CDS YP_882268.1 118464488 4528862 3148659..3149936 1 NC_008595.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 3149936 amt 4528862 amt Mycobacterium avium 104 ammonium transporter YP_882268.1 3148659 D 243243 CDS YP_882269.1 118462742 4527813 3150048..3150809 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3150809 4527813 MAV_3085 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882269.1 3150048 D 243243 CDS YP_882270.1 118464599 4530110 3150875..3151561 1 NC_008595.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR00025; efflux ABC transporter 3151561 4530110 MAV_3086 Mycobacterium avium 104 efflux ABC transporter YP_882270.1 3150875 D 243243 CDS YP_882271.1 118463269 4528134 3151580..3152203 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3152203 4528134 MAV_3088 Mycobacterium avium 104 TetR family transcriptional regulator YP_882271.1 3151580 D 243243 CDS YP_882272.1 118463854 4529953 complement(3152169..3152384) 1 NC_008595.1 identified by match to protein family HMM PF03966; hypothetical protein 3152384 4529953 MAV_3087 Mycobacterium avium 104 hypothetical protein YP_882272.1 3152169 R 243243 CDS YP_882273.1 118462833 4528647 complement(3152381..3155377) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3155377 4528647 MAV_3089 Mycobacterium avium 104 acyl-CoA synthetase YP_882273.1 3152381 R 243243 CDS YP_882274.1 118462841 4526023 complement(3155678..3155959) 1 NC_008595.1 hypothetical protein 3155959 4526023 MAV_3090 Mycobacterium avium 104 hypothetical protein YP_882274.1 3155678 R 243243 CDS YP_882275.1 118466746 4526347 3156425..3156925 1 NC_008595.1 hypothetical protein 3156925 4526347 MAV_3091 Mycobacterium avium 104 hypothetical protein YP_882275.1 3156425 D 243243 CDS YP_882276.1 118466193 4530183 3156933..3157679 1 NC_008595.1 hypothetical protein 3157679 4530183 MAV_3092 Mycobacterium avium 104 hypothetical protein YP_882276.1 3156933 D 243243 CDS YP_882277.1 118465591 4527139 3157755..3159377 1 NC_008595.1 identified by match to protein family HMM PF00732; match to protein family HMM PF05199; glucose-methanol-choline oxidoreductase 3159377 4527139 MAV_3093 Mycobacterium avium 104 glucose-methanol-choline oxidoreductase YP_882277.1 3157755 D 243243 CDS YP_882278.1 118465596 4527144 3159370..3161166 1 NC_008595.1 identified by match to protein family HMM PF00723; glycosyl hydrolase, family protein 15 3161166 4527144 MAV_3094 Mycobacterium avium 104 glycosyl hydrolase, family protein 15 YP_882278.1 3159370 D 243243 CDS YP_882279.1 118466260 4526879 3161197..3162219 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 3162219 4526879 MAV_3095 Mycobacterium avium 104 short chain dehydrogenase YP_882279.1 3161197 D 243243 CDS YP_882280.1 118463401 4528028 3162216..3163322 1 NC_008595.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing enzyme 3163322 4528028 MAV_3096 Mycobacterium avium 104 mandelate racemase/muconate lactonizing enzyme YP_882280.1 3162216 D 243243 CDS YP_882281.1 118463653 4528555 complement(3163424..3164194) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 3164194 4528555 MAV_3097 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_882281.1 3163424 R 243243 CDS YP_882282.1 118466728 4530666 complement(3164210..3165022) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 3165022 4530666 MAV_3098 Mycobacterium avium 104 carveol dehydrogenase YP_882282.1 3164210 R 243243 CDS YP_882283.1 118462517 4528595 complement(3165029..3166006) 1 NC_008595.1 hypothetical protein 3166006 4528595 MAV_3099 Mycobacterium avium 104 hypothetical protein YP_882283.1 3165029 R 243243 CDS YP_882284.1 118465093 4529984 complement(3166101..3167237) 1 NC_008595.1 sulfotransferase 3167237 4529984 MAV_3100 Mycobacterium avium 104 sulfotransferase YP_882284.1 3166101 R 243243 CDS YP_882285.1 118465618 4528734 complement(3167242..3168084) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 3168084 4528734 MAV_3101 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_882285.1 3167242 R 243243 CDS YP_882286.1 118464700 4527889 3168286..3169239 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3169239 4527889 MAV_3102 Mycobacterium avium 104 LysR family transcriptional regulator YP_882286.1 3168286 D 243243 CDS YP_882287.1 118465407 4525667 3169432..3170121 1 NC_008595.1 identified by match to protein family HMM PF03861; match to protein family HMM TIGR00229; hypothetical protein 3170121 4525667 MAV_3103 Mycobacterium avium 104 hypothetical protein YP_882287.1 3169432 D 243243 CDS YP_882288.1 118464107 4525868 3170364..3172088 1 NC_008595.1 identified by match to protein family HMM PF00005; macrolide ABC transporter ATP-binding protein 3172088 4525868 MAV_3104 Mycobacterium avium 104 macrolide ABC transporter ATP-binding protein YP_882288.1 3170364 D 243243 CDS YP_882289.1 118464338 4529140 3172094..3173377 1 NC_008595.1 identified by match to protein family HMM PF00067; P450 heme-thiolate protein 3173377 4529140 MAV_3106 Mycobacterium avium 104 P450 heme-thiolate protein YP_882289.1 3172094 D 243243 CDS YP_882290.1 118463420 4530057 complement(3173360..3174421) 1 NC_008595.1 identified by match to protein family HMM PF00195; match to protein family HMM PF02797; Pks11 protein 3174421 4530057 MAV_3105 Mycobacterium avium 104 Pks11 protein YP_882290.1 3173360 R 243243 CDS YP_882291.1 118464601 4530112 complement(3174582..3177686) 1 NC_008595.1 identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; polyketide synthase 3177686 4530112 MAV_3107 Mycobacterium avium 104 polyketide synthase YP_882291.1 3174582 R 243243 CDS YP_882292.1 118462561 4528620 complement(3177689..3184075) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801; erythronolide synthase, modules 3 and 4 3184075 4528620 MAV_3108 Mycobacterium avium 104 erythronolide synthase, modules 3 and 4 YP_882292.1 3177689 R 243243 CDS YP_882293.1 118463404 4528031 complement(3184095..3190469) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; RifB protein 3190469 4528031 MAV_3109 Mycobacterium avium 104 RifB protein YP_882293.1 3184095 R 243243 CDS YP_882294.1 118467197 4528431 complement(3190529..3191590) 1 NC_008595.1 identified by match to protein family HMM PF00195; match to protein family HMM PF02797; Pks10 protein 3191590 4528431 MAV_3110 Mycobacterium avium 104 Pks10 protein YP_882294.1 3190529 R 243243 CDS YP_882295.1 118462303 4525648 complement(3191699..3193117) 1 NC_008595.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 3193117 argH 4525648 argH Mycobacterium avium 104 argininosuccinate lyase YP_882295.1 3191699 R 243243 CDS YP_882296.1 118465513 4528930 complement(3193152..3194348) 1 NC_008595.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 3194348 argG 4528930 argG Mycobacterium avium 104 argininosuccinate synthase YP_882296.1 3193152 R 243243 CDS YP_882297.1 118466353 4530493 complement(3194376..3194870) 1 NC_008595.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3194870 argR 4530493 argR Mycobacterium avium 104 arginine repressor YP_882297.1 3194376 R 243243 CDS YP_882298.1 118464590 4530101 complement(3194867..3195796) 1 NC_008595.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 3195796 argF 4530101 argF Mycobacterium avium 104 ornithine carbamoyltransferase YP_882298.1 3194867 R 243243 CDS YP_882299.1 118464044 4529016 complement(3195793..3197022) 1 NC_008595.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 3197022 argD 4529016 argD Mycobacterium avium 104 acetylornithine aminotransferase YP_882299.1 3195793 R 243243 CDS YP_882300.1 118463262 4528127 complement(3197117..3198004) 1 NC_008595.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 3198004 argB 4528127 argB Mycobacterium avium 104 acetylglutamate kinase YP_882300.1 3197117 R 243243 CDS YP_882301.1 118462840 4528655 complement(3198001..3199215) 1 NC_008595.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 3199215 argJ 4528655 argJ Mycobacterium avium 104 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_882301.1 3198001 R 243243 CDS YP_882302.1 118466947 4530259 complement(3199212..3200255) 1 NC_008595.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 3200255 argC 4530259 argC Mycobacterium avium 104 N-acetyl-gamma-glutamyl-phosphate reductase YP_882302.1 3199212 R 243243 CDS YP_882303.1 118466258 4526877 complement(3200303..3202789) 1 NC_008595.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 3202789 pheT 4526877 pheT Mycobacterium avium 104 phenylalanyl-tRNA synthetase subunit beta YP_882303.1 3200303 R 243243 CDS YP_882304.1 118465916 4528998 complement(3202789..3203817) 1 NC_008595.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 3203817 pheS 4528998 pheS Mycobacterium avium 104 phenylalanyl-tRNA synthetase subunit alpha YP_882304.1 3202789 R 243243 CDS YP_882305.1 118465362 4529222 complement(3204028..3204831) 1 NC_008595.1 hypothetical protein 3204831 4529222 MAV_3121 Mycobacterium avium 104 hypothetical protein YP_882305.1 3204028 R 243243 CDS YP_882306.1 118462244 4526930 complement(3204856..3205776) 1 NC_008595.1 identified by match to protein family HMM PF00211; adenylate and guanylate cyclase catalytic domain-containing protein 3205776 4526930 MAV_3122 Mycobacterium avium 104 adenylate and guanylate cyclase catalytic domain-containing protein YP_882306.1 3204856 R 243243 CDS YP_882307.1 118466564 4529113 3205992..3207059 1 NC_008595.1 hypothetical protein 3207059 4529113 MAV_3124 Mycobacterium avium 104 hypothetical protein YP_882307.1 3205992 D 243243 CDS YP_882308.1 118464222 4526902 complement(3207046..3207837) 1 NC_008595.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; TsnR protein 3207837 4526902 MAV_3123 Mycobacterium avium 104 TsnR protein YP_882308.1 3207046 R 243243 CDS YP_882309.1 118462550 4530551 complement(3207868..3208254) 1 NC_008595.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 3208254 rplT 4530551 rplT Mycobacterium avium 104 50S ribosomal protein L20 YP_882309.1 3207868 R 243243 CDS YP_882310.1 118466256 4526875 complement(3208345..3208539) 1 NC_008595.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 3208539 rpmI 4526875 rpmI Mycobacterium avium 104 50S ribosomal protein L35 YP_882310.1 3208345 R 243243 CDS YP_882311.1 118466944 4530256 complement(3208582..3209103) 1 NC_008595.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 3209103 infC 4530256 infC Mycobacterium avium 104 translation initiation factor IF-3 YP_882311.1 3208582 R 243243 CDS YP_882312.1 118467307 4530299 3209782..3213009 1 NC_008595.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 3213009 lysS 4530299 lysS Mycobacterium avium 104 lysyl-tRNA synthetase YP_882312.1 3209782 D 243243 CDS YP_882313.1 118465558 4525808 3213169..3214572 1 NC_008595.1 identified by match to protein family HMM PF00756; esterase 3214572 4525808 MAV_3129 Mycobacterium avium 104 esterase YP_882313.1 3213169 D 243243 CDS YP_882314.1 118466910 4529455 3214754..3215323 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3215323 4529455 MAV_3130 Mycobacterium avium 104 TetR family transcriptional regulator YP_882314.1 3214754 D 243243 CDS YP_882315.1 118466339 4528770 3215464..3217575 1 NC_008595.1 identified by match to protein family HMM PF00899; hypothetical protein 3217575 4528770 MAV_3131 Mycobacterium avium 104 hypothetical protein YP_882315.1 3215464 D 243243 CDS YP_882316.1 118465484 4527237 3217685..3219550 1 NC_008595.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; GGDEF domain-containing protein 3219550 4527237 MAV_3132 Mycobacterium avium 104 GGDEF domain-containing protein YP_882316.1 3217685 D 243243 CDS YP_882317.1 118464921 4528561 complement(3219569..3220288) 1 NC_008595.1 hypothetical protein 3220288 4528561 MAV_3133 Mycobacterium avium 104 hypothetical protein YP_882317.1 3219569 R 243243 CDS YP_882318.1 118465294 4529330 3220663..3220899 1 NC_008595.1 hypothetical protein 3220899 4529330 MAV_3134 Mycobacterium avium 104 hypothetical protein YP_882318.1 3220663 D 243243 CDS YP_882319.1 118463037 4528878 complement(3220901..3223816) 1 NC_008595.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 3223816 uvrA 4528878 uvrA Mycobacterium avium 104 excinuclease ABC subunit A YP_882319.1 3220901 R 243243 CDS YP_882320.1 118466480 4527610 3223915..3224610 1 NC_008595.1 identified by match to protein family HMM PF00753; hydrolase 3224610 4527610 MAV_3136 Mycobacterium avium 104 hydrolase YP_882320.1 3223915 D 243243 CDS YP_882321.1 118466967 4530366 complement(3224628..3225020) 1 NC_008595.1 identified by match to protein family HMM PF00582; universal stress protein family protein, putative 3225020 4530366 MAV_3137 Mycobacterium avium 104 universal stress protein family protein, putative YP_882321.1 3224628 R 243243 CDS YP_882322.1 118465416 4529965 3225444..3226940 1 NC_008595.1 hypothetical protein 3226940 4529965 MAV_3138 Mycobacterium avium 104 hypothetical protein YP_882322.1 3225444 D 243243 CDS YP_882323.1 118465988 4526130 3226993..3227715 1 NC_008595.1 identified by match to protein family HMM PF02308; Mg2+ transporter-C (MgtC) family protein 3227715 4526130 MAV_3139 Mycobacterium avium 104 Mg2+ transporter-C (MgtC) family protein YP_882323.1 3226993 D 243243 CDS YP_882324.1 118465532 4530007 complement(3227718..3229136) 1 NC_008595.1 identified by match to protein family HMM PF07690; drug efflux membrane protein 3229136 4530007 MAV_3140 Mycobacterium avium 104 drug efflux membrane protein YP_882324.1 3227718 R 243243 CDS YP_882325.1 118463533 4526839 complement(3229194..3231362) 1 NC_008595.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 3231362 uvrB 4526839 uvrB Mycobacterium avium 104 excinuclease ABC subunit B YP_882325.1 3229194 R 243243 CDS YP_882326.1 118465474 4527227 complement(3231456..3231962) 1 NC_008595.1 hypothetical protein 3231962 4527227 MAV_3142 Mycobacterium avium 104 hypothetical protein YP_882326.1 3231456 R 243243 CDS YP_882327.1 118464597 4530108 complement(3231946..3233007) 1 NC_008595.1 hypothetical protein 3233007 4530108 MAV_3143 Mycobacterium avium 104 hypothetical protein YP_882327.1 3231946 R 243243 CDS YP_882328.1 118466147 4527913 complement(3233020..3233289) 1 NC_008595.1 hypothetical protein 3233289 4527913 MAV_3144 Mycobacterium avium 104 hypothetical protein YP_882328.1 3233020 R 243243 CDS YP_882329.1 118462529 4527672 complement(3233522..3235597) 1 NC_008595.1 identified by match to protein family HMM PF00069; PknF protein 3235597 4527672 MAV_3145 Mycobacterium avium 104 PknF protein YP_882329.1 3233522 R 243243 CDS YP_882330.1 118463460 4529702 3235901..3238423 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061; ABC transporter ATP-binding protein 3238423 4529702 MAV_3146 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882330.1 3235901 D 243243 CDS YP_882331.1 118462308 4525653 3238521..3238985 1 NC_008595.1 identified by match to protein family HMM PF04167; hypothetical protein 3238985 4525653 MAV_3147 Mycobacterium avium 104 hypothetical protein YP_882331.1 3238521 D 243243 CDS YP_882332.1 118466631 4526987 3238982..3239980 1 NC_008595.1 identified by match to protein family HMM PF01068; match to protein family HMM PF04679; match to protein family HMM TIGR02779; DNA polymerase LigD ligase subunit 3239980 ligD 4526987 ligD Mycobacterium avium 104 DNA polymerase LigD ligase subunit YP_882332.1 3238982 D 243243 CDS YP_882333.1 118466096 4527725 3239980..3240768 1 NC_008595.1 identified by match to protein family HMM PF01149; match to protein family HMM PF06831; formamidopyrimidine DNA-glyxosylase 3240768 4527725 MAV_3149 Mycobacterium avium 104 formamidopyrimidine DNA-glyxosylase YP_882333.1 3239980 D 243243 CDS YP_882334.1 118464041 4529013 3240778..3241191 1 NC_008595.1 hypothetical protein 3241191 4529013 MAV_3150 Mycobacterium avium 104 hypothetical protein YP_882334.1 3240778 D 243243 CDS YP_882335.1 118464608 4530119 complement(3241202..3242425) 1 NC_008595.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain; dephospho-CoA kinase/protein folding accessory domain-containing protein 3242425 coaE 4530119 coaE Mycobacterium avium 104 dephospho-CoA kinase/protein folding accessory domain-containing protein YP_882335.1 3241202 R 243243 CDS YP_882336.1 118464486 4528860 complement(3242438..3243880) 1 NC_008595.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 3243880 rpsA 4528860 rpsA Mycobacterium avium 104 30S ribosomal protein S1 YP_882336.1 3242438 R 243243 CDS YP_882337.1 118463937 4528117 complement(3243984..3245495) 1 NC_008595.1 identified by match to protein family HMM PF03055; retinal pigment epithelial membrane protein 3245495 4528117 MAV_3153 Mycobacterium avium 104 retinal pigment epithelial membrane protein YP_882337.1 3243984 R 243243 CDS YP_882338.1 118463341 4529211 complement(3245528..3246157) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3246157 4529211 MAV_3154 Mycobacterium avium 104 TetR family transcriptional regulator YP_882338.1 3245528 R 243243 CDS YP_882339.1 118462804 4529024 complement(3246170..3248911) 1 NC_008595.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3248911 4529024 MAV_3155 Mycobacterium avium 104 DNA polymerase I YP_882339.1 3246170 R 243243 CDS YP_882340.1 118462243 4526929 3249019..3249459 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 3249459 4526929 MAV_3156 Mycobacterium avium 104 hypothetical protein YP_882340.1 3249019 D 243243 CDS YP_882341.1 118463880 4527758 3249456..3250670 1 NC_008595.1 lipid-transfer protein 3250670 4527758 MAV_3157 Mycobacterium avium 104 lipid-transfer protein YP_882341.1 3249456 D 243243 CDS YP_882342.1 118463323 4529563 complement(3250781..3251404) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF03861; response regulator 3251404 4529563 MAV_3158 Mycobacterium avium 104 response regulator YP_882342.1 3250781 R 243243 CDS YP_882343.1 118462637 4529377 complement(3251523..3251657) 1 NC_008595.1 hypothetical protein 3251657 4529377 MAV_3159 Mycobacterium avium 104 hypothetical protein YP_882343.1 3251523 R 243243 CDS YP_882344.1 118462699 4526679 complement(3252278..3253603) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3253603 4526679 MAV_3161 Mycobacterium avium 104 transposase, Mutator family protein YP_882344.1 3252278 R 243243 CDS YP_882345.1 118467309 4530301 3253684..3255015 1 NC_008595.1 identified by match to protein family HMM PF00211; adenylate cyclase 3255015 4530301 MAV_3162 Mycobacterium avium 104 adenylate cyclase YP_882345.1 3253684 D 243243 CDS YP_882346.1 118466101 4527730 3255094..3255636 1 NC_008595.1 identified by match to protein family HMM PF03729; integral membrane protein 3255636 4527730 MAV_3163 Mycobacterium avium 104 integral membrane protein YP_882346.1 3255094 D 243243 CDS YP_882347.1 118465629 4528746 3255723..3257195 1 NC_008595.1 identified by match to protein family HMM PF01654; cytochrome D ubiquinol oxidase subunit 1 3257195 4528746 MAV_3164 Mycobacterium avium 104 cytochrome D ubiquinol oxidase subunit 1 YP_882347.1 3255723 D 243243 CDS YP_882348.1 118465122 4530475 3257229..3258269 1 NC_008595.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome D ubiquinol oxidase, subunit II 3258269 cydB 4530475 cydB Mycobacterium avium 104 cytochrome D ubiquinol oxidase, subunit II YP_882348.1 3257229 D 243243 CDS YP_882349.1 118464329 4529834 3258332..3259954 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02857; cysteine ABC transporter ATP-binding protein/permease 3259954 cydD 4529834 cydD Mycobacterium avium 104 cysteine ABC transporter ATP-binding protein/permease YP_882349.1 3258332 D 243243 CDS YP_882350.1 118463899 4530576 3259941..3261623 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3261623 4530576 MAV_3167 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882350.1 3259941 D 243243 CDS YP_882351.1 118463474 4525527 complement(3261630..3263027) 1 NC_008595.1 identified by match to protein family HMM PF04329; match to protein family HMM PF04330; match to protein family HMM PF04331; hypothetical protein 3263027 4525527 MAV_3168 Mycobacterium avium 104 hypothetical protein YP_882351.1 3261630 R 243243 CDS YP_882352.1 118466740 4526341 complement(3263169..3264071) 1 NC_008595.1 identified by match to protein family HMM PF02551; Acyl-CoA thioesterase 3264071 4526341 MAV_3169 Mycobacterium avium 104 Acyl-CoA thioesterase YP_882352.1 3263169 R 243243 CDS YP_882353.1 118464646 4528981 complement(3264144..3265499) 1 NC_008595.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 3265499 pyk 4528981 pyk Mycobacterium avium 104 pyruvate kinase YP_882353.1 3264144 R 243243 CDS YP_882354.1 118463752 4527996 complement(3265629..3265982) 1 NC_008595.1 hypothetical protein 3265982 4527996 MAV_3171 Mycobacterium avium 104 hypothetical protein YP_882354.1 3265629 R 243243 CDS YP_882355.1 118466037 4528045 complement(3266090..3267412) 1 NC_008595.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3267412 4528045 MAV_3172 Mycobacterium avium 104 prolipoprotein diacylglyceryl transferase YP_882355.1 3266090 R 243243 CDS YP_882356.1 118465189 4530386 complement(3267409..3268224) 1 NC_008595.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 3268224 trpA 4530386 trpA Mycobacterium avium 104 tryptophan synthase subunit alpha YP_882356.1 3267409 R 243243 CDS YP_882357.1 118462807 4529027 complement(3268221..3269492) 1 NC_008595.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 3269492 trpB 4529027 trpB Mycobacterium avium 104 tryptophan synthase subunit beta YP_882357.1 3268221 R 243243 CDS YP_882358.1 118467273 4527075 complement(3269564..3270382) 1 NC_008595.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 3270382 trpC 4527075 trpC Mycobacterium avium 104 indole-3-glycerol-phosphate synthase YP_882358.1 3269564 R 243243 CDS YP_882359.1 118462802 4525771 complement(3270496..3271176) 1 NC_008595.1 identified by match to protein family HMM TIGR02234; hypothetical protein 3271176 4525771 MAV_3176 Mycobacterium avium 104 hypothetical protein YP_882359.1 3270496 R 243243 CDS YP_882360.1 118462893 4527500 complement(3271173..3272705) 1 NC_008595.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 3272705 trpE 4527500 trpE Mycobacterium avium 104 anthranilate synthase component I YP_882360.1 3271173 R 243243 CDS YP_882361.1 118462347 4525692 3272878..3273336 1 NC_008595.1 identified by match to protein family HMM PF00578; antioxidant, AhpC/TSA family protein 3273336 4525692 MAV_3178 Mycobacterium avium 104 antioxidant, AhpC/TSA family protein YP_882361.1 3272878 D 243243 CDS YP_882362.1 118464942 4528203 complement(3273340..3274446) 1 NC_008595.1 identified by match to protein family HMM PF01699; calcium/proton exchanger 3274446 chaA 4528203 chaA Mycobacterium avium 104 calcium/proton exchanger YP_882362.1 3273340 R 243243 CDS YP_882363.1 118465199 4530396 complement(3274549..3274896) 1 NC_008595.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 3274896 hisI 4530396 hisI Mycobacterium avium 104 phosphoribosyl-AMP cyclohydrolase YP_882363.1 3274549 R 243243 CDS YP_882364.1 118466095 4527724 complement(3274893..3275690) 1 NC_008595.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 3275690 hisF 4527724 hisF Mycobacterium avium 104 imidazole glycerol phosphate synthase subunit HisF YP_882364.1 3274893 R 243243 CDS YP_882365.1 118466813 4527378 complement(3275692..3276492) 1 NC_008595.1 identified by match to protein family HMM PF00459; inositol monophosphatase 3276492 4527378 MAV_3182 Mycobacterium avium 104 inositol monophosphatase YP_882365.1 3275692 R 243243 CDS YP_882366.1 118463357 4529891 complement(3276499..3277230) 1 NC_008595.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 3277230 4529891 MAV_3183 Mycobacterium avium 104 phosphoribosyl isomerase A YP_882366.1 3276499 R 243243 CDS YP_882367.1 118464576 4530280 complement(3277251..3277871) 1 NC_008595.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 3277871 hisH 4530280 hisH Mycobacterium avium 104 imidazole glycerol phosphate synthase subunit HisH YP_882367.1 3277251 R 243243 CDS YP_882368.1 118464037 4529009 complement(3277868..3278491) 1 NC_008595.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 3278491 hisB 4529009 hisB Mycobacterium avium 104 imidazoleglycerol-phosphate dehydratase YP_882368.1 3277868 R 243243 CDS YP_882369.1 118466104 4527733 complement(3278488..3279684) 1 NC_008595.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 3279684 hisC 4527733 hisC Mycobacterium avium 104 histidinol-phosphate aminotransferase YP_882369.1 3278488 R 243243 CDS YP_882370.1 118465943 4527939 complement(3279681..3281084) 1 NC_008595.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 3281084 hisD 4527939 hisD Mycobacterium avium 104 histidinol dehydrogenase YP_882370.1 3279681 R 243243 CDS YP_882371.1 118462408 4525718 3281217..3281630 1 NC_008595.1 identified by match to protein family HMM TIGR00026; hypothetical protein 3281630 4525718 MAV_3188 Mycobacterium avium 104 hypothetical protein YP_882371.1 3281217 D 243243 CDS YP_882372.1 118465337 4526650 complement(3281742..3282596) 1 NC_008595.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 3282596 nadC 4526650 nadC Mycobacterium avium 104 nicotinate-nucleotide pyrophosphorylase YP_882372.1 3281742 R 243243 CDS YP_882373.1 118464628 4526785 complement(3282599..3284191) 1 NC_008595.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3284191 nadB 4526785 nadB Mycobacterium avium 104 L-aspartate oxidase YP_882373.1 3282599 R 243243 CDS YP_882374.1 118465712 4527446 complement(3284188..3285237) 1 NC_008595.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 3285237 nadA 4527446 nadA Mycobacterium avium 104 quinolinate synthetase YP_882374.1 3284188 R 243243 CDS YP_882375.1 118464975 4527467 3285323..3286009 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, NUDIX family protein 3286009 4527467 MAV_3192 Mycobacterium avium 104 hydrolase, NUDIX family protein YP_882375.1 3285323 D 243243 CDS YP_882376.1 118466930 4527765 3286171..3287511 1 NC_008595.1 identified by match to protein family HMM PF03583; secretory lipase 3287511 4527765 MAV_3194 Mycobacterium avium 104 secretory lipase YP_882376.1 3286171 D 243243 CDS YP_882377.1 118462400 4525944 complement(3287477..3288154) 1 NC_008595.1 hypothetical protein 3288154 4525944 MAV_3193 Mycobacterium avium 104 hypothetical protein YP_882377.1 3287477 R 243243 CDS YP_882378.1 118464129 4528830 complement(3288151..3288387) 1 NC_008595.1 hypothetical protein 3288387 4528830 MAV_3195 Mycobacterium avium 104 hypothetical protein YP_882378.1 3288151 R 243243 CDS YP_882379.1 118463442 4528322 complement(3288437..3289474) 1 NC_008595.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 3289474 bioB 4528322 bioB Mycobacterium avium 104 biotin synthase YP_882379.1 3288437 R 243243 CDS YP_882380.1 118463776 4530127 3289605..3289796 1 NC_008595.1 hypothetical protein 3289796 4530127 MAV_3197 Mycobacterium avium 104 hypothetical protein YP_882380.1 3289605 D 243243 CDS YP_882381.1 118462608 4528512 3289908..3291740 1 NC_008595.1 hypothetical protein 3291740 4528512 MAV_3198 Mycobacterium avium 104 hypothetical protein YP_882381.1 3289908 D 243243 CDS YP_882382.1 118463493 4529072 3291744..3292106 1 NC_008595.1 hypothetical protein 3292106 4529072 MAV_3199 Mycobacterium avium 104 hypothetical protein YP_882382.1 3291744 D 243243 CDS YP_882383.1 118464052 4529492 3292103..3293467 1 NC_008595.1 hypothetical protein 3293467 4529492 MAV_3200 Mycobacterium avium 104 hypothetical protein YP_882383.1 3292103 D 243243 CDS YP_882384.1 118466400 4526242 3295707..3297128 1 NC_008595.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00924; transmembrane protein 3297128 4526242 MAV_3202 Mycobacterium avium 104 transmembrane protein YP_882384.1 3295707 D 243243 CDS YP_882385.1 118467127 4526154 complement(3297206..3297715) 1 NC_008595.1 hypothetical protein 3297715 4526154 MAV_3203 Mycobacterium avium 104 hypothetical protein YP_882385.1 3297206 R 243243 CDS YP_882386.1 118462415 4525725 complement(3297715..3298395) 1 NC_008595.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 3298395 bioD 4525725 bioD Mycobacterium avium 104 dithiobiotin synthetase YP_882386.1 3297715 R 243243 CDS YP_882387.1 118462956 4526324 complement(3298400..3299545) 1 NC_008595.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 3299545 bioF 4526324 bioF Mycobacterium avium 104 8-amino-7-oxononanoate synthase YP_882387.1 3298400 R 243243 CDS YP_882388.1 118463676 4528521 complement(3299550..3300866) 1 NC_008595.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 3300866 bioA 4528521 bioA Mycobacterium avium 104 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_882388.1 3299550 R 243243 CDS YP_882389.1 118463955 4526607 3300929..3301396 1 NC_008595.1 hypothetical protein 3301396 4526607 MAV_3207 Mycobacterium avium 104 hypothetical protein YP_882389.1 3300929 D 243243 CDS YP_882390.1 118464813 4527632 3301728..3302597 1 NC_008595.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 3302597 4527632 MAV_3208 Mycobacterium avium 104 NlpC/P60 family protein YP_882390.1 3301728 D 243243 CDS YP_882391.1 118466781 4529339 3302697..3304859 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase domain-containing protein 3304859 4529339 MAV_3209 Mycobacterium avium 104 acyltransferase domain-containing protein YP_882391.1 3302697 D 243243 CDS YP_882392.1 118465044 4525823 3304987..3307185 1 NC_008595.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; glycogen debranching enzyme GlgX 3307185 glgX 4525823 glgX Mycobacterium avium 104 glycogen debranching enzyme GlgX YP_882392.1 3304987 D 243243 CDS YP_882393.1 118466785 4529343 3307189..3309489 1 NC_008595.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02401; malto-oligosyltrehalose synthase 3309489 treY 4529343 treY Mycobacterium avium 104 malto-oligosyltrehalose synthase YP_882393.1 3307189 D 243243 CDS YP_882394.1 118466160 4528782 3309482..3311254 1 NC_008595.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402; malto-oligosyltrehalose trehalohydrolase 3311254 treZ 4528782 treZ Mycobacterium avium 104 malto-oligosyltrehalose trehalohydrolase YP_882394.1 3309482 D 243243 CDS YP_882395.1 118463348 4529882 3311291..3311452 1 NC_008595.1 hypothetical protein 3311452 4529882 MAV_3213 Mycobacterium avium 104 hypothetical protein YP_882395.1 3311291 D 243243 CDS YP_882396.1 118462801 4525770 complement(3311460..3312788) 1 NC_008595.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR-family protein transcriptional regulator 3312788 4525770 MAV_3214 Mycobacterium avium 104 GntR-family protein transcriptional regulator YP_882396.1 3311460 R 243243 CDS YP_882397.1 118464502 4525545 3312819..3313484 1 NC_008595.1 flavin-nucleotide-binding protein 3313484 4525545 MAV_3215 Mycobacterium avium 104 flavin-nucleotide-binding protein YP_882397.1 3312819 D 243243 CDS YP_882398.1 118462435 4528298 complement(3313492..3314397) 1 NC_008595.1 identified by match to protein family HMM PF01569; PAP2 superfamily protein 3314397 4528298 MAV_3216 Mycobacterium avium 104 PAP2 superfamily protein YP_882398.1 3313492 R 243243 CDS YP_882399.1 118466523 4527196 complement(3314407..3315690) 1 NC_008595.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 3315690 ilvA 4527196 ilvA Mycobacterium avium 104 threonine dehydratase YP_882399.1 3314407 R 243243 CDS YP_882400.1 118463066 4527565 complement(3315729..3316166) 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 3316166 4527565 MAV_3218 Mycobacterium avium 104 hypothetical protein YP_882400.1 3315729 R 243243 CDS YP_882401.1 118463731 4528139 complement(3316176..3316964) 1 NC_008595.1 hypothetical protein 3316964 4528139 MAV_3219 Mycobacterium avium 104 hypothetical protein YP_882401.1 3316176 R 243243 CDS YP_882402.1 118465907 4528989 complement(3317117..3319018) 1 NC_008595.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 3319018 4528989 MAV_3220 Mycobacterium avium 104 glycerol-3-phosphate acyltransferase YP_882402.1 3317117 R 243243 CDS YP_882403.1 118464822 4527641 complement(3319015..3320835) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA dehydrogenase 3320835 4527641 MAV_3221 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882403.1 3319015 R 243243 CDS YP_882404.1 118463330 4529200 complement(3320857..3321273) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 3321273 4529200 MAV_3222 Mycobacterium avium 104 MerR family transcriptional regulator YP_882404.1 3320857 R 243243 CDS YP_882405.1 118462959 4526327 3321332..3321778 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 3321778 4526327 MAV_3223 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_882405.1 3321332 D 243243 CDS YP_882406.1 118463133 4529658 complement(3321896..3325429) 1 NC_008595.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 3325429 dnaE 4529658 dnaE Mycobacterium avium 104 DNA polymerase III subunit alpha YP_882406.1 3321896 R 243243 CDS YP_882407.1 118463760 4528004 complement(3325494..3325925) 1 NC_008595.1 hypothetical protein 3325925 4528004 MAV_3225 Mycobacterium avium 104 hypothetical protein YP_882407.1 3325494 R 243243 CDS YP_882408.1 118465479 4527232 complement(3326044..3326847) 1 NC_008595.1 identified by match to protein family HMM PF00106; ketoacyl reductase 3326847 4527232 MAV_3226 Mycobacterium avium 104 ketoacyl reductase YP_882408.1 3326044 R 243243 CDS YP_882409.1 118462427 4528290 complement(3326852..3327868) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 3327868 4528290 MAV_3227 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_882409.1 3326852 R 243243 CDS YP_882410.1 118464614 4526771 3328093..3328506 1 NC_008595.1 identified by match to protein family HMM PF01152; globin 3328506 4526771 MAV_3228 Mycobacterium avium 104 globin YP_882410.1 3328093 D 243243 CDS YP_882411.1 118466669 4526619 3328530..3329288 1 NC_008595.1 hypothetical protein 3329288 4526619 MAV_3229 Mycobacterium avium 104 hypothetical protein YP_882411.1 3328530 D 243243 CDS YP_882412.1 118463205 4527532 complement(3329289..3330173) 1 NC_008595.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase d 3330173 4527532 MAV_3230 Mycobacterium avium 104 ribosomal large subunit pseudouridine synthase d YP_882412.1 3329289 R 243243 CDS YP_882413.1 118467010 4529480 complement(3330208..3330756) 1 NC_008595.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 3330756 lspA 4529480 lspA Mycobacterium avium 104 lipoprotein signal peptidase YP_882413.1 3330208 R 243243 CDS YP_882414.1 118464462 4527055 3330828..3331766 1 NC_008595.1 identified by match to protein family HMM PF00710; L-asparaginase 3331766 4527055 MAV_3233 Mycobacterium avium 104 L-asparaginase YP_882414.1 3330828 D 243243 CDS YP_882415.1 118466313 4528355 complement(3331731..3333107) 1 NC_008595.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3333107 4528355 MAV_3232 Mycobacterium avium 104 DNA polymerase IV YP_882415.1 3331731 R 243243 CDS YP_882416.1 118466228 4526574 complement(3333229..3334068) 1 NC_008595.1 hypothetical protein 3334068 4526574 MAV_3234 Mycobacterium avium 104 hypothetical protein YP_882416.1 3333229 R 243243 CDS YP_882417.1 118463176 4529878 complement(3334184..3337345) 1 NC_008595.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 3337345 ileS 4529878 ileS Mycobacterium avium 104 isoleucyl-tRNA synthetase YP_882417.1 3334184 R 243243 CDS YP_882418.1 118464089 4525850 complement(3337669..3337905) 1 NC_008595.1 hypothetical protein 3337905 4525850 MAV_3236 Mycobacterium avium 104 hypothetical protein YP_882418.1 3337669 R 243243 CDS YP_882419.1 118467193 4528427 complement(3338522..3339640) 1 NC_008595.1 identified by match to protein family HMM PF03060; 2-nitropropane dioxygenase, NPD 3339640 4528427 MAV_3237 Mycobacterium avium 104 2-nitropropane dioxygenase, NPD YP_882419.1 3338522 R 243243 CDS YP_882420.1 118466970 4530369 complement(3339703..3340272) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 3340272 pcaC 4530369 pcaC Mycobacterium avium 104 hypothetical protein YP_882420.1 3339703 R 243243 CDS YP_882421.1 118465061 4527037 complement(3340393..3359031) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF07993; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; match to protein family HMM TIGR01746; syringomycin synthetase 3359031 4527037 MAV_3239 Mycobacterium avium 104 syringomycin synthetase YP_882421.1 3340393 R 243243 CDS YP_882422.1 118465607 4527866 complement(3359109..3359948) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 3359948 4527866 MAV_3240 Mycobacterium avium 104 transposase YP_882422.1 3359109 R 243243 CDS YP_882423.1 118463954 4526606 complement(3360026..3360157) 1 NC_008595.1 ISAfe7, transposase OrfA 3360157 4526606 MAV_3241 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_882423.1 3360026 R 243243 CDS YP_882424.1 118465910 4528992 complement(3360154..3364440) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; actinomycin synthetase II 3364440 4528992 MAV_3242 Mycobacterium avium 104 actinomycin synthetase II YP_882424.1 3360154 R 243243 CDS YP_882425.1 118462635 4529375 complement(3365016..3372674) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; match to protein family HMM TIGR01746; linear gramicidin synthetase subunit B 3372674 4529375 MAV_3243 Mycobacterium avium 104 linear gramicidin synthetase subunit B YP_882425.1 3365016 R 243243 CDS YP_882426.1 118465509 4528926 complement(3372671..3382918) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; linear gramicidin synthetase subunit D 3382918 4528926 MAV_3244 Mycobacterium avium 104 linear gramicidin synthetase subunit D YP_882426.1 3372671 R 243243 CDS YP_882427.1 118463754 4527998 complement(3382963..3383193) 1 NC_008595.1 identified by match to protein family HMM PF03621; hypothetical protein 3383193 4527998 MAV_3245 Mycobacterium avium 104 hypothetical protein YP_882427.1 3382963 R 243243 CDS YP_882428.1 118464330 4529835 complement(3383617..3384942) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3384942 4529835 MAV_3246 Mycobacterium avium 104 transposase, Mutator family protein YP_882428.1 3383617 R 243243 CDS YP_882429.1 118464605 4530116 3385510..3385929 1 NC_008595.1 identified by match to protein family HMM PF05423; MmpS4 protein 3385929 4530116 MAV_3247 Mycobacterium avium 104 MmpS4 protein YP_882429.1 3385510 D 243243 CDS YP_882430.1 118462538 4530539 3385926..3388817 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; Mmp14A protein 3388817 4530539 MAV_3248 Mycobacterium avium 104 Mmp14A protein YP_882430.1 3385926 D 243243 CDS YP_882431.1 118463450 4529692 3388936..3391794 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; Mmp14A protein 3391794 4529692 MAV_3249 Mycobacterium avium 104 Mmp14A protein YP_882431.1 3388936 D 243243 CDS YP_882432.1 118466584 4527374 3392019..3392966 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01188; daunorubicin resistance ATP-binding protein 3392966 4527374 MAV_3250 Mycobacterium avium 104 daunorubicin resistance ATP-binding protein YP_882432.1 3392019 D 243243 CDS YP_882433.1 118466736 4530674 3392963..3393703 1 NC_008595.1 identified by match to protein family HMM PF01061; ABC transporter efflux protein, DrrB family protein 3393703 4530674 MAV_3251 Mycobacterium avium 104 ABC transporter efflux protein, DrrB family protein YP_882433.1 3392963 D 243243 CDS YP_882434.1 118462417 4525727 3393700..3394494 1 NC_008595.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR01248; daunorubicin resistance protein C 3394494 4525727 MAV_3252 Mycobacterium avium 104 daunorubicin resistance protein C YP_882434.1 3393700 D 243243 CDS YP_882435.1 118467159 4527590 complement(3394519..3395190) 1 NC_008595.1 hypothetical protein 3395190 4527590 MAV_3253 Mycobacterium avium 104 hypothetical protein YP_882435.1 3394519 R 243243 CDS YP_882436.1 118463114 4527176 3395418..3396692 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3396692 4527176 MAV_3254 Mycobacterium avium 104 transposase, Mutator family protein YP_882436.1 3395418 D 243243 CDS YP_882437.1 118463198 4527525 3396778..3397800 1 NC_008595.1 identified by match to protein family HMM PF00535; glycosyltransferase GtfTB 3397800 4527525 MAV_3255 Mycobacterium avium 104 glycosyltransferase GtfTB YP_882437.1 3396778 D 243243 CDS YP_882438.1 118462634 4529374 3397803..3398852 1 NC_008595.1 identified by match to protein family HMM PF04230; polysaccharide pyruvyl transferase 3398852 4529374 MAV_3256 Mycobacterium avium 104 polysaccharide pyruvyl transferase YP_882438.1 3397803 D 243243 CDS YP_882439.1 118466926 4527761 3398870..3399526 1 NC_008595.1 hypothetical protein 3399526 4527761 MAV_3257 Mycobacterium avium 104 hypothetical protein YP_882439.1 3398870 D 243243 CDS YP_882440.1 118466342 4530482 3399659..3400915 1 NC_008595.1 identified by match to protein family HMM PF03033; glycosyltransferase 28 3400915 4530482 MAV_3258 Mycobacterium avium 104 glycosyltransferase 28 YP_882440.1 3399659 D 243243 CDS YP_882441.1 118465457 4526225 complement(3400922..3401701) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; dehydrogenase DhgA 3401701 4526225 MAV_3259 Mycobacterium avium 104 dehydrogenase DhgA YP_882441.1 3400922 R 243243 CDS YP_882442.1 118464893 4529622 complement(3401775..3402521) 1 NC_008595.1 MtfD protein 3402521 4529622 MAV_3260 Mycobacterium avium 104 MtfD protein YP_882442.1 3401775 R 243243 CDS YP_882443.1 118467015 4529485 complement(3402693..3403493) 1 NC_008595.1 identified by match to protein family HMM PF05711; methyltransferase MtfC 3403493 4529485 MAV_3261 Mycobacterium avium 104 methyltransferase MtfC YP_882443.1 3402693 R 243243 CDS YP_882444.1 118466354 4530494 complement(3403596..3404786) 1 NC_008595.1 identified by match to protein family HMM PF03033; glycosyl transferase 3404786 4530494 MAV_3262 Mycobacterium avium 104 glycosyl transferase YP_882444.1 3403596 R 243243 CDS YP_882445.1 118465489 4527242 3405110..3405454 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 3405454 4527242 MAV_3263 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_882445.1 3405110 D 243243 CDS YP_882446.1 118464938 4528199 3405532..3406371 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 3406371 4528199 MAV_3264 Mycobacterium avium 104 transposase YP_882446.1 3405532 D 243243 CDS YP_882447.1 118465574 4526760 complement(3406637..3407914) 1 NC_008595.1 identified by match to protein family HMM PF03033; glycosyl transferase 3407914 4526760 MAV_3265 Mycobacterium avium 104 glycosyl transferase YP_882447.1 3406637 R 243243 CDS YP_882448.1 118464881 4529610 complement(3408037..3408858) 1 NC_008595.1 identified by match to protein family HMM PF05711; MtfB protein 3408858 4529610 MAV_3266 Mycobacterium avium 104 MtfB protein YP_882448.1 3408037 R 243243 CDS YP_882449.1 118466024 4529910 3408831..3408959 1 NC_008595.1 hypothetical protein 3408959 4529910 MAV_3267 Mycobacterium avium 104 hypothetical protein YP_882449.1 3408831 D 243243 CDS YP_882450.1 118464733 4529420 complement(3409125..3410252) 1 NC_008595.1 MtfA protein 3410252 4529420 MAV_3268 Mycobacterium avium 104 MtfA protein YP_882450.1 3409125 R 243243 CDS YP_882451.1 118464065 4529505 complement(3410516..3411565) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase 3411565 4529505 MAV_3269 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_882451.1 3410516 R 243243 CDS YP_882452.1 118464961 4528701 complement(3411697..3412722) 1 NC_008595.1 hypothetical protein 3412722 4528701 MAV_3270 Mycobacterium avium 104 hypothetical protein YP_882452.1 3411697 R 243243 CDS YP_882453.1 118463539 4526806 complement(3412780..3413619) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 3413619 4526806 MAV_3271 Mycobacterium avium 104 transposase YP_882453.1 3412780 R 243243 CDS YP_882454.1 118464273 4528228 complement(3413697..3414041) 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 3414041 4528228 MAV_3272 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_882454.1 3413697 R 243243 CDS YP_882455.1 118466941 4527776 complement(3414521..3415450) 1 NC_008595.1 hypothetical protein 3415450 4527776 MAV_3273 Mycobacterium avium 104 hypothetical protein YP_882455.1 3414521 R 243243 CDS YP_882456.1 118462236 4525574 complement(3415757..3416920) 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase 3416920 4525574 MAV_3274 Mycobacterium avium 104 acyltransferase YP_882456.1 3415757 R 243243 CDS YP_882457.1 118466361 4529923 complement(3417128..3418408) 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 3418408 4529923 MAV_3275 Mycobacterium avium 104 beta-lactamase YP_882457.1 3417128 R 243243 CDS YP_882458.1 118467011 4529481 complement(3418478..3419458) 1 NC_008595.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3419458 4529481 MAV_3276 Mycobacterium avium 104 arginine/ornithine transport system ATPase YP_882458.1 3418478 R 243243 CDS YP_882459.1 118464912 4530747 complement(3419541..3421793) 1 NC_008595.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3421793 4530747 MAV_3277 Mycobacterium avium 104 methylmalonyl-CoA mutase YP_882459.1 3419541 R 243243 CDS YP_882460.1 118466038 4528046 complement(3421799..3423676) 1 NC_008595.1 identified by match to protein family HMM PF01642; match to protein family HMM TIGR00642; methylmalonyl-CoA mutase, small subunit 3423676 mutA 4528046 mutA Mycobacterium avium 104 methylmalonyl-CoA mutase, small subunit YP_882460.1 3421799 R 243243 CDS YP_882461.1 118463308 4526003 3423857..3424624 1 NC_008595.1 hypothetical protein 3424624 4526003 MAV_3279 Mycobacterium avium 104 hypothetical protein YP_882461.1 3423857 D 243243 CDS YP_882462.1 118467017 4529487 3424686..3425675 1 NC_008595.1 hypothetical protein 3425675 4529487 MAV_3280 Mycobacterium avium 104 hypothetical protein YP_882462.1 3424686 D 243243 CDS YP_882463.1 118465320 4526516 complement(3425711..3426085) 1 NC_008595.1 hypothetical protein 3426085 4526516 MAV_3281 Mycobacterium avium 104 hypothetical protein YP_882463.1 3425711 R 243243 CDS YP_882464.1 118464487 4528861 complement(3426082..3427536) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 3427536 4528861 MAV_3282 Mycobacterium avium 104 hypothetical protein YP_882464.1 3426082 R 243243 CDS YP_882465.1 118463210 4527537 complement(3427533..3428252) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two component system response regulator 3428252 4527537 MAV_3283 Mycobacterium avium 104 two component system response regulator YP_882465.1 3427533 R 243243 CDS YP_882466.1 118463986 4530345 3428543..3428878 1 NC_008595.1 hypothetical protein 3428878 4530345 MAV_3284 Mycobacterium avium 104 hypothetical protein YP_882466.1 3428543 D 243243 CDS YP_882467.1 118464755 4527651 3428886..3429413 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 3429413 4527651 MAV_3285 Mycobacterium avium 104 hypothetical protein YP_882467.1 3428886 D 243243 CDS YP_882468.1 118464272 4528227 3429526..3429717 1 NC_008595.1 hypothetical protein 3429717 4528227 MAV_3286 Mycobacterium avium 104 hypothetical protein YP_882468.1 3429526 D 243243 CDS YP_882469.1 118464287 4529575 3429802..3430500 1 NC_008595.1 hypothetical protein 3430500 4529575 MAV_3287 Mycobacterium avium 104 hypothetical protein YP_882469.1 3429802 D 243243 CDS YP_882470.1 118463645 4528547 3430891..3431190 1 NC_008595.1 LpqQ protein 3431190 4528547 MAV_3288 Mycobacterium avium 104 LpqQ protein YP_882470.1 3430891 D 243243 CDS YP_882471.1 118463375 4528953 complement(3431209..3431565) 1 NC_008595.1 hypothetical protein 3431565 4528953 MAV_3289 Mycobacterium avium 104 hypothetical protein YP_882471.1 3431209 R 243243 CDS YP_882472.1 118465385 4529677 complement(3431584..3432717) 1 NC_008595.1 identified by match to protein family HMM PF01145; secreted protein 3432717 4529677 MAV_3290 Mycobacterium avium 104 secreted protein YP_882472.1 3431584 R 243243 CDS YP_882473.1 118464558 4530777 complement(3432748..3433185) 1 NC_008595.1 identified by match to protein family HMM PF01957; nodulation efficiency protein D (NfeD) 3433185 4530777 MAV_3291 Mycobacterium avium 104 nodulation efficiency protein D (NfeD) YP_882473.1 3432748 R 243243 CDS YP_882474.1 118466444 4527117 3433243..3434169 1 NC_008595.1 hypothetical protein 3434169 4527117 MAV_3292 Mycobacterium avium 104 hypothetical protein YP_882474.1 3433243 D 243243 CDS YP_882475.1 118466061 4530031 complement(3434173..3435183) 1 NC_008595.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 3435183 hemH 4530031 hemH Mycobacterium avium 104 ferrochelatase YP_882475.1 3434173 R 243243 CDS YP_882476.1 118462702 4526682 complement(3435190..3435999) 1 NC_008595.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 3435999 4526682 MAV_3294 Mycobacterium avium 104 enoyl-(acyl carrier protein) reductase YP_882476.1 3435190 R 243243 CDS YP_882477.1 118462315 4529633 complement(3436034..3436801) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM TIGR01830; 3-oxoacyl-(acyl-carrier-protein) reductase 3436801 fabG 4529633 fabG Mycobacterium avium 104 3-oxoacyl-(acyl-carrier-protein) reductase YP_882477.1 3436034 R 243243 CDS YP_882478.1 118462694 4526674 3436903..3437781 1 NC_008595.1 hypothetical protein 3437781 4526674 MAV_3296 Mycobacterium avium 104 hypothetical protein YP_882478.1 3436903 D 243243 CDS YP_882479.1 118463234 4528808 complement(3437864..3438871) 1 NC_008595.1 identified by match to protein family HMM PF00092; hypothetical protein 3438871 4528808 MAV_3297 Mycobacterium avium 104 hypothetical protein YP_882479.1 3437864 R 243243 CDS YP_882480.1 118463999 4529261 complement(3438879..3439829) 1 NC_008595.1 identified by match to protein family HMM PF01882; hypothetical protein 3439829 4529261 MAV_3298 Mycobacterium avium 104 hypothetical protein YP_882480.1 3438879 R 243243 CDS YP_882481.1 118464497 4525540 complement(3439826..3440968) 1 NC_008595.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728; MoxR protein 3440968 4525540 MAV_3299 Mycobacterium avium 104 MoxR protein YP_882481.1 3439826 R 243243 CDS YP_882482.1 118467056 4526512 complement(3441091..3441825) 1 NC_008595.1 identified by match to protein family HMM PF00877; invasin 1 3441825 4526512 MAV_3300 Mycobacterium avium 104 invasin 1 YP_882482.1 3441091 R 243243 CDS YP_882483.1 118465185 4530382 complement(3441851..3443203) 1 NC_008595.1 identified by match to protein family HMM PF00877; invasion protein 3443203 4530382 MAV_3301 Mycobacterium avium 104 invasion protein YP_882483.1 3441851 R 243243 CDS YP_882484.1 118462963 4526331 complement(3443493..3444038) 1 NC_008595.1 hypothetical protein 3444038 4526331 MAV_3302 Mycobacterium avium 104 hypothetical protein YP_882484.1 3443493 R 243243 CDS YP_882485.2 161579546 4527831 3444269..3447082 1 NC_008595.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 3447082 acnA 4527831 acnA Mycobacterium avium 104 aconitate hydratase YP_882485.2 3444269 D 243243 CDS YP_882486.1 118465959 4528178 3447118..3447696 1 NC_008595.1 identified by match to protein family HMM PF00440; HTH-type transcriptional repressor AcnR 3447696 4528178 MAV_3305 Mycobacterium avium 104 HTH-type transcriptional repressor AcnR YP_882486.1 3447118 D 243243 CDS YP_882487.1 118465126 4530479 complement(3447693..3447890) 1 NC_008595.1 hypothetical protein 3447890 4530479 MAV_3304 Mycobacterium avium 104 hypothetical protein YP_882487.1 3447693 R 243243 CDS YP_882488.1 118467319 4530312 complement(3448005..3449642) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3449642 4530312 MAV_3306 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882488.1 3448005 R 243243 CDS YP_882489.1 118466585 4527375 complement(3449666..3450475) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3450475 4527375 MAV_3307 Mycobacterium avium 104 enoyl-CoA hydratase YP_882489.1 3449666 R 243243 CDS YP_882490.1 118464906 4530741 complement(3450498..3450851) 1 NC_008595.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 3450851 trx 4530741 trx Mycobacterium avium 104 thioredoxin YP_882490.1 3450498 R 243243 CDS YP_882491.1 118464348 4529150 3450993..3452822 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 3452822 4529150 MAV_3309 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882491.1 3450993 D 243243 CDS YP_882492.1 118466297 4529544 3452912..3453688 1 NC_008595.1 27 kDa lipoprotein antigen 3453688 4529544 MAV_3310 Mycobacterium avium 104 27 kDa lipoprotein antigen YP_882492.1 3452912 D 243243 CDS YP_882493.1 118465555 4525804 complement(3453717..3453866) 1 NC_008595.1 hypothetical protein 3453866 4525804 MAV_3311 Mycobacterium avium 104 hypothetical protein YP_882493.1 3453717 R 243243 CDS YP_882494.1 118464024 4528820 3453868..3454536 1 NC_008595.1 hypothetical protein 3454536 4528820 MAV_3312 Mycobacterium avium 104 hypothetical protein YP_882494.1 3453868 D 243243 CDS YP_882495.1 118463266 4528131 complement(3454568..3454915) 1 NC_008595.1 identified by match to protein family HMM PF01883; hypothetical protein 3454915 4528131 MAV_3313 Mycobacterium avium 104 hypothetical protein YP_882495.1 3454568 R 243243 CDS YP_882496.1 118464953 4528215 complement(3454890..3455369) 1 NC_008595.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; SUF system FeS assembly protein, NifU family protein 3455369 4528215 MAV_3314 Mycobacterium avium 104 SUF system FeS assembly protein, NifU family protein YP_882496.1 3454890 R 243243 CDS YP_882497.1 118464227 4528600 complement(3455373..3456599) 1 NC_008595.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01979; cysteine desulfurase 3456599 4528600 MAV_3315 Mycobacterium avium 104 cysteine desulfurase YP_882497.1 3455373 R 243243 CDS YP_882498.1 118466387 4526188 complement(3456623..3457405) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC 3457405 sufC 4526188 sufC Mycobacterium avium 104 FeS assembly ATPase SufC YP_882498.1 3456623 R 243243 CDS YP_882499.1 118465589 4527136 complement(3457402..3458592) 1 NC_008595.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD 3458592 sufD 4527136 sufD Mycobacterium avium 104 FeS assembly protein SufD YP_882499.1 3457402 R 243243 CDS YP_882500.1 118463302 4525997 complement(3458592..3460040) 1 NC_008595.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB 3460040 sufB 4525997 sufB Mycobacterium avium 104 FeS assembly protein SufB YP_882500.1 3458592 R 243243 CDS YP_882501.1 118466484 4527614 complement(3460037..3460762) 1 NC_008595.1 identified by match to protein family HMM PF01022; DNA-binding protein 3460762 4527614 MAV_3319 Mycobacterium avium 104 DNA-binding protein YP_882501.1 3460037 R 243243 CDS YP_882502.1 118463656 4525948 3460885..3462588 1 NC_008595.1 hypothetical protein 3462588 4525948 MAV_3320 Mycobacterium avium 104 hypothetical protein YP_882502.1 3460885 D 243243 CDS YP_882503.1 118464995 4526261 3462612..3463520 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding subunit 3463520 4526261 MAV_3321 Mycobacterium avium 104 ABC transporter ATP-binding subunit YP_882503.1 3462612 D 243243 CDS YP_882504.1 118462657 4529085 3463517..3464296 1 NC_008595.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR00025; ABC transporter efflux protein, DrrB family protein 3464296 4529085 MAV_3322 Mycobacterium avium 104 ABC transporter efflux protein, DrrB family protein YP_882504.1 3463517 D 243243 CDS YP_882505.1 118464120 4526291 3464471..3465424 1 NC_008595.1 identified by match to protein family HMM PF02628; cytochrome aa3 controlling protein 3465424 4526291 MAV_3324 Mycobacterium avium 104 cytochrome aa3 controlling protein YP_882505.1 3464471 D 243243 CDS YP_882506.1 118463207 4527534 complement(3465374..3466033) 1 NC_008595.1 hypothetical protein 3466033 4527534 MAV_3323 Mycobacterium avium 104 hypothetical protein YP_882506.1 3465374 R 243243 CDS YP_882507.1 118464661 4528258 3466032..3467006 1 NC_008595.1 identified by match to protein family HMM PF00107; quinone oxidoreductase 3467006 4528258 MAV_3325 Mycobacterium avium 104 quinone oxidoreductase YP_882507.1 3466032 D 243243 CDS YP_882508.1 118462366 4529178 complement(3467183..3468052) 1 NC_008595.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 3468052 cyoE 4529178 cyoE Mycobacterium avium 104 protoheme IX farnesyltransferase YP_882508.1 3467183 R 243243 CDS YP_882509.1 118466946 4530258 3468366..3470465 1 NC_008595.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3470465 tkt 4530258 tkt Mycobacterium avium 104 transketolase YP_882509.1 3468366 D 243243 CDS YP_882510.1 118463166 4529867 3470533..3471603 1 NC_008595.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 3471603 tal 4529867 tal Mycobacterium avium 104 transaldolase YP_882510.1 3470533 D 243243 CDS YP_882511.2 161579554 4526428 3471600..3473156 1 NC_008595.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 3473156 zwf 4526428 zwf Mycobacterium avium 104 glucose-6-phosphate 1-dehydrogenase YP_882511.2 3471600 D 243243 CDS YP_882512.1 118464713 4529400 3473163..3474083 1 NC_008595.1 identified by match to protein family HMM TIGR00534; OpcA protein 3474083 opcA 4529400 opcA Mycobacterium avium 104 OpcA protein YP_882512.1 3473163 D 243243 CDS YP_882513.1 118464150 4526459 3474080..3474835 1 NC_008595.1 identified by match to protein family HMM PF01182; match to protein family HMM TIGR01198; 6-phosphogluconolactonase 3474835 pgl 4526459 pgl Mycobacterium avium 104 6-phosphogluconolactonase YP_882513.1 3474080 D 243243 CDS YP_882514.1 118465676 4525735 3474886..3475275 1 NC_008595.1 hypothetical protein 3475275 4525735 MAV_3332 Mycobacterium avium 104 hypothetical protein YP_882514.1 3474886 D 243243 CDS YP_882515.1 118464825 4529727 3475294..3476223 1 NC_008595.1 identified by match to protein family HMM PF00850; histone deacetylase 3476223 4529727 MAV_3333 Mycobacterium avium 104 histone deacetylase YP_882515.1 3475294 D 243243 CDS YP_882516.1 118466914 4529459 complement(3476225..3477211) 1 NC_008595.1 identified by match to protein family HMM PF00248; general stress protein 69 3477211 4529459 MAV_3334 Mycobacterium avium 104 general stress protein 69 YP_882516.1 3476225 R 243243 CDS YP_882517.1 118463609 4527556 complement(3477311..3478090) 1 NC_008595.1 hypothetical protein 3478090 4527556 MAV_3335 Mycobacterium avium 104 hypothetical protein YP_882517.1 3477311 R 243243 CDS YP_882518.1 118465776 4526911 complement(3478166..3480973) 1 NC_008595.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 3480973 ppc 4526911 ppc Mycobacterium avium 104 phosphoenolpyruvate carboxylase YP_882518.1 3478166 R 243243 CDS YP_882519.1 118464051 4529491 3481077..3481994 1 NC_008595.1 identified by match to protein family HMM PF00296; monooxygenase 3481994 4529491 MAV_3337 Mycobacterium avium 104 monooxygenase YP_882519.1 3481077 D 243243 CDS YP_882520.1 118464944 4528205 complement(3482012..3482245) 1 NC_008595.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 3482245 secG 4528205 secG Mycobacterium avium 104 preprotein translocase subunit SecG YP_882520.1 3482012 R 243243 CDS YP_882521.1 118465485 4527238 complement(3482276..3483061) 1 NC_008595.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3483061 tpiA 4527238 tpiA Mycobacterium avium 104 triosephosphate isomerase YP_882521.1 3482276 R 243243 CDS YP_882522.1 118466356 4530496 complement(3483058..3484305) 1 NC_008595.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3484305 pgk 4530496 pgk Mycobacterium avium 104 phosphoglycerate kinase YP_882522.1 3483058 R 243243 CDS YP_882523.1 118462645 4529386 complement(3484309..3485328) 1 NC_008595.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase, type I 3485328 gap 4529386 gap Mycobacterium avium 104 glyceraldehyde-3-phosphate dehydrogenase, type I YP_882523.1 3484309 R 243243 CDS YP_882524.1 118463360 4529894 complement(3485452..3486864) 1 NC_008595.1 dehydrogenase 3486864 4529894 MAV_3342 Mycobacterium avium 104 dehydrogenase YP_882524.1 3485452 R 243243 CDS YP_882525.1 118464229 4528602 complement(3486869..3488614) 1 NC_008595.1 hypothetical protein 3488614 4528602 MAV_3343 Mycobacterium avium 104 hypothetical protein YP_882525.1 3486869 R 243243 CDS YP_882526.1 118466064 4530034 complement(3488786..3489073) 1 NC_008595.1 hypothetical protein 3489073 4530034 MAV_3344 Mycobacterium avium 104 hypothetical protein YP_882526.1 3488786 R 243243 CDS YP_882527.1 118465324 4526520 3489131..3489367 1 NC_008595.1 hypothetical protein 3489367 4526520 MAV_3345 Mycobacterium avium 104 hypothetical protein YP_882527.1 3489131 D 243243 CDS YP_882528.1 118466039 4528047 3489364..3490173 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase domain-containing protein 3490173 4528047 MAV_3346 Mycobacterium avium 104 acyltransferase domain-containing protein YP_882528.1 3489364 D 243243 CDS YP_882529.1 118463649 4528551 3490189..3490407 1 NC_008595.1 acyl-CoA synthase 3490407 4528551 MAV_3348 Mycobacterium avium 104 acyl-CoA synthase YP_882529.1 3490189 D 243243 CDS YP_882530.1 118465298 4526552 complement(3490390..3491427) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 3491427 4526552 MAV_3347 Mycobacterium avium 104 transposase YP_882530.1 3490390 R 243243 CDS YP_882531.1 118462880 4527486 3491550..3492893 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3492893 4527486 MAV_3349 Mycobacterium avium 104 acyl-CoA synthetase YP_882531.1 3491550 D 243243 CDS YP_882532.1 118462526 4527669 3492893..3494164 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 3494164 4527669 MAV_3350 Mycobacterium avium 104 alpha/beta hydrolase YP_882532.1 3492893 D 243243 CDS YP_882533.1 118467074 4526452 3494336..3495187 1 NC_008595.1 hypothetical protein 3495187 4526452 MAV_3351 Mycobacterium avium 104 hypothetical protein YP_882533.1 3494336 D 243243 CDS YP_882534.1 118466540 4527008 complement(3495260..3496666) 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 3496666 4527008 MAV_3352 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_882534.1 3495260 R 243243 CDS YP_882535.1 118465961 4528180 complement(3496816..3497781) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 3497781 4528180 MAV_3353 Mycobacterium avium 104 PPE family protein YP_882535.1 3496816 R 243243 CDS YP_882536.1 118466879 4526698 complement(3497871..3498224) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 3498224 4526698 MAV_3354 Mycobacterium avium 104 hypothetical protein YP_882536.1 3497871 R 243243 CDS YP_882537.1 118462279 4529284 complement(3498281..3499645) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 3499645 4529284 MAV_3355 Mycobacterium avium 104 PPE family protein YP_882537.1 3498281 R 243243 CDS YP_882538.1 118466467 4528689 complement(3499657..3500910) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 3500910 4528689 MAV_3356 Mycobacterium avium 104 PPE family protein YP_882538.1 3499657 R 243243 CDS YP_882539.1 118467097 4526358 complement(3501733..3502716) 1 NC_008595.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 3502716 4526358 MAV_3357 Mycobacterium avium 104 hypothetical protein YP_882539.1 3501733 R 243243 CDS YP_882540.1 118465391 4529683 complement(3502707..3503783) 1 NC_008595.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 3503783 4529683 MAV_3358 Mycobacterium avium 104 hypothetical protein YP_882540.1 3502707 R 243243 CDS YP_882541.1 118465926 4528485 complement(3503780..3504676) 1 NC_008595.1 identified by match to protein family HMM PF03668; hypothetical protein 3504676 4528485 MAV_3359 Mycobacterium avium 104 hypothetical protein YP_882541.1 3503780 R 243243 CDS YP_882542.1 118463596 4529782 complement(3504709..3506595) 1 NC_008595.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 3506595 uvrC 4529782 uvrC Mycobacterium avium 104 excinuclease ABC subunit C YP_882542.1 3504709 R 243243 CDS YP_882543.1 118464331 4529836 3506767..3507852 1 NC_008595.1 identified by match to protein family HMM PF08007; cupin superfamily protein 3507852 4529836 MAV_3361 Mycobacterium avium 104 cupin superfamily protein YP_882543.1 3506767 D 243243 CDS YP_882544.1 118467304 4530296 3507885..3508223 1 NC_008595.1 hypothetical protein 3508223 4530296 MAV_3362 Mycobacterium avium 104 hypothetical protein YP_882544.1 3507885 D 243243 CDS YP_882545.1 118462862 4527089 complement(3508257..3508721) 1 NC_008595.1 hypothetical protein 3508721 4527089 MAV_3363 Mycobacterium avium 104 hypothetical protein YP_882545.1 3508257 R 243243 CDS YP_882546.1 118465726 4527461 complement(3508718..3509200) 1 NC_008595.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 3509200 ribH 4527461 ribH Mycobacterium avium 104 6,7-dimethyl-8-ribityllumazine synthase YP_882546.1 3508718 R 243243 CDS YP_882547.1 118464982 4527474 complement(3509250..3510527) 1 NC_008595.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 3510527 4527474 MAV_3365 Mycobacterium avium 104 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_882547.1 3509250 R 243243 CDS YP_882548.1 118462391 4525934 complement(3510649..3511248) 1 NC_008595.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 3511248 ribE 4525934 ribE Mycobacterium avium 104 riboflavin synthase subunit alpha YP_882548.1 3510649 R 243243 CDS YP_882549.1 118466791 4529349 3511367..3512074 1 NC_008595.1 identified by match to protein family HMM PF07161; LprG protein 3512074 4529349 MAV_3367 Mycobacterium avium 104 LprG protein YP_882549.1 3511367 D 243243 CDS YP_882550.1 118463468 4525521 3512071..3513627 1 NC_008595.1 identified by match to protein family HMM PF07690; aminoglycosides/tetracycline-transport integral membrane protein 3513627 4525521 MAV_3369 Mycobacterium avium 104 aminoglycosides/tetracycline-transport integral membrane protein YP_882550.1 3512071 D 243243 CDS YP_882551.1 118462896 4528158 complement(3513624..3514649) 1 NC_008595.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 3514649 ribD 4528158 ribD Mycobacterium avium 104 riboflavin biosynthesis protein RibD YP_882551.1 3513624 R 243243 CDS YP_882552.1 118463895 4530572 complement(3514646..3515344) 1 NC_008595.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3515344 rpe 4530572 rpe Mycobacterium avium 104 ribulose-phosphate 3-epimerase YP_882552.1 3514646 R 243243 CDS YP_882553.1 118463294 4525988 complement(3515454..3516773) 1 NC_008595.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Fmu protein 3516773 4525988 MAV_3371 Mycobacterium avium 104 Fmu protein YP_882553.1 3515454 R 243243 CDS YP_882554.1 118464892 4529621 complement(3516845..3517798) 1 NC_008595.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3517798 fmt 4529621 fmt Mycobacterium avium 104 methionyl-tRNA formyltransferase YP_882554.1 3516845 R 243243 CDS YP_882555.1 118464324 4529829 3517950..3518777 1 NC_008595.1 identified by match to protein family HMM PF01170; match to protein family HMM PF01209; match to protein family HMM PF02353; methyltransferase, UbiE/COQ5 family protein 3518777 4529829 MAV_3373 Mycobacterium avium 104 methyltransferase, UbiE/COQ5 family protein YP_882555.1 3517950 D 243243 CDS YP_882556.1 118465302 4526556 complement(3518783..3519268) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3519268 4526556 MAV_3374 Mycobacterium avium 104 MarR family transcriptional regulator YP_882556.1 3518783 R 243243 CDS YP_882557.1 118465545 4525793 complement(3519396..3521420) 1 NC_008595.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 3521420 priA 4525793 priA Mycobacterium avium 104 primosome assembly protein PriA YP_882557.1 3519396 R 243243 CDS YP_882558.1 118464847 4527963 complement(3521448..3522239) 1 NC_008595.1 identified by match to protein family HMM PF07947; hypothetical protein 3522239 4527963 MAV_3376 Mycobacterium avium 104 hypothetical protein YP_882558.1 3521448 R 243243 CDS YP_882559.1 118467095 4526395 3522238..3523200 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 3523200 4526395 MAV_3377 Mycobacterium avium 104 alpha/beta hydrolase YP_882559.1 3522238 D 243243 CDS YP_882560.1 118462511 4528589 3523246..3524736 1 NC_008595.1 identified by match to protein family HMM PF01266; lipolytic enzyme 3524736 4528589 MAV_3378 Mycobacterium avium 104 lipolytic enzyme YP_882560.1 3523246 D 243243 CDS YP_882561.1 118466925 4527760 complement(3524738..3525604) 1 NC_008595.1 identified by match to protein family HMM PF00296; MmcJ protein 3525604 4527760 MAV_3379 Mycobacterium avium 104 MmcJ protein YP_882561.1 3524738 R 243243 CDS YP_882562.1 118463514 4527694 3525775..3526758 1 NC_008595.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 3526758 4527694 MAV_3380 Mycobacterium avium 104 AsnC family transcriptional regulator YP_882562.1 3525775 D 243243 CDS YP_882563.1 118463440 4528320 3526768..3527334 1 NC_008595.1 identified by match to protein family HMM PF01243; signal transduction histidine kinase, nitrogen specific 3527334 4528320 MAV_3381 Mycobacterium avium 104 signal transduction histidine kinase, nitrogen specific YP_882563.1 3526768 D 243243 CDS YP_882564.1 118465537 4530013 complement(3527410..3528621) 1 NC_008595.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3528621 metK 4530013 metK Mycobacterium avium 104 S-adenosylmethionine synthetase YP_882564.1 3527410 R 243243 CDS YP_882565.1 118463550 4526817 complement(3528716..3529990) 1 NC_008595.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3529990 coaBC 4526817 coaBC Mycobacterium avium 104 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_882565.1 3528716 R 243243 CDS YP_882566.1 118463858 4529957 complement(3530012..3530338) 1 NC_008595.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3530338 4529957 MAV_3384 Mycobacterium avium 104 DNA-directed RNA polymerase subunit omega YP_882566.1 3530012 R 243243 CDS YP_882567.1 118464596 4530107 complement(3530415..3531020) 1 NC_008595.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3531020 gmk 4530107 gmk Mycobacterium avium 104 guanylate kinase YP_882567.1 3530415 R 243243 CDS YP_882568.1 118462761 4527851 complement(3531172..3531486) 1 NC_008595.1 MihF protein 3531486 4527851 MAV_3386 Mycobacterium avium 104 MihF protein YP_882568.1 3531172 R 243243 CDS YP_882569.1 118463471 4525524 3531965..3532387 1 NC_008595.1 identified by match to protein family HMM PF00376; match to protein family HMM PF03459; TobE protein 3532387 4525524 MAV_3387 Mycobacterium avium 104 TobE protein YP_882569.1 3531965 D 243243 CDS YP_882570.1 118466105 4527734 complement(3532393..3533217) 1 NC_008595.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 3533217 pyrF 4527734 pyrF Mycobacterium avium 104 orotidine 5'-phosphate decarboxylase YP_882570.1 3532393 R 243243 CDS YP_882571.1 118466762 4530757 complement(3533214..3536567) 1 NC_008595.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 3536567 carB 4530757 carB Mycobacterium avium 104 carbamoyl phosphate synthase large subunit YP_882571.1 3533214 R 243243 CDS YP_882572.1 118464947 4528209 complement(3536567..3537688) 1 NC_008595.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 3537688 carA 4528209 carA Mycobacterium avium 104 carbamoyl phosphate synthase small subunit YP_882572.1 3536567 R 243243 CDS YP_882573.1 118465714 4527448 complement(3537685..3538197) 1 NC_008595.1 hypothetical protein 3538197 4527448 MAV_3391 Mycobacterium avium 104 hypothetical protein YP_882573.1 3537685 R 243243 CDS YP_882574.1 118464737 4529424 complement(3538259..3539551) 1 NC_008595.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 3539551 pyrC 4529424 pyrC Mycobacterium avium 104 dihydroorotase YP_882574.1 3538259 R 243243 CDS YP_882575.1 118464017 4528813 complement(3539548..3540504) 1 NC_008595.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 3540504 pyrB 4528813 pyrB Mycobacterium avium 104 aspartate carbamoyltransferase catalytic subunit YP_882575.1 3539548 R 243243 CDS YP_882576.1 118464931 4528571 complement(3540501..3541073) 1 NC_008595.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 3541073 4528571 MAV_3394 Mycobacterium avium 104 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_882576.1 3540501 R 243243 CDS YP_882577.1 118466747 4526348 3541214..3542419 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 3542419 4526348 MAV_3395 Mycobacterium avium 104 beta-lactamase YP_882577.1 3541214 D 243243 CDS YP_882578.1 118463424 4530061 3542416..3542970 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 3542970 4530061 MAV_3396 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_882578.1 3542416 D 243243 CDS YP_882579.1 118462705 4526686 complement(3542971..3545691) 1 NC_008595.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02985; match to protein family HMM PF03130; match to protein family HMM PF03486; match to protein family HMM PF07992; oxidoreductase/HEAT repeat-containing protein 3545691 4526686 MAV_3397 Mycobacterium avium 104 oxidoreductase/HEAT repeat-containing protein YP_882579.1 3542971 R 243243 CDS YP_882580.1 118462679 4530606 complement(3545691..3546428) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3546428 4530606 MAV_3398 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882580.1 3545691 R 243243 CDS YP_882581.1 118464707 4529394 complement(3546425..3547285) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 3547285 4529394 MAV_3399 Mycobacterium avium 104 ABC transporter permease YP_882581.1 3546425 R 243243 CDS YP_882582.1 118463680 4528527 complement(3547282..3548670) 1 NC_008595.1 ABC transporter substrate-binding protein 3548670 4528527 MAV_3400 Mycobacterium avium 104 ABC transporter substrate-binding protein YP_882582.1 3547282 R 243243 CDS YP_882583.1 118465688 4525747 complement(3548696..3548926) 1 NC_008595.1 identified by match to protein family HMM PF00037; hypothetical protein 3548926 4525747 MAV_3401 Mycobacterium avium 104 hypothetical protein YP_882583.1 3548696 R 243243 CDS YP_882584.1 118464863 4530699 complement(3548923..3549675) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR-family protein transcriptional regulator 3549675 4530699 MAV_3402 Mycobacterium avium 104 GntR-family protein transcriptional regulator YP_882584.1 3548923 R 243243 CDS YP_882585.1 118465550 4525798 3549915..3550721 1 NC_008595.1 hypothetical protein 3550721 4525798 MAV_3403 Mycobacterium avium 104 hypothetical protein YP_882585.1 3549915 D 243243 CDS YP_882586.1 118465915 4528997 3550809..3551126 1 NC_008595.1 hypothetical protein 3551126 4528997 MAV_3404 Mycobacterium avium 104 hypothetical protein YP_882586.1 3550809 D 243243 CDS YP_882587.1 118464519 4529439 3551151..3551819 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; TcrA protein 3551819 4529439 MAV_3406 Mycobacterium avium 104 TcrA protein YP_882587.1 3551151 D 243243 CDS YP_882588.1 118464100 4525861 complement(3551801..3553204) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 3553204 4525861 MAV_3405 Mycobacterium avium 104 hypothetical protein YP_882588.1 3551801 R 243243 CDS YP_882589.1 118462580 4530200 3553305..3553547 1 NC_008595.1 hypothetical protein 3553547 4530200 MAV_3407 Mycobacterium avium 104 hypothetical protein YP_882589.1 3553305 D 243243 CDS YP_882590.1 118464127 4526298 complement(3553552..3556404) 1 NC_008595.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711; Orn/Lys/Arg decarboxylase 3556404 4526298 MAV_3408 Mycobacterium avium 104 Orn/Lys/Arg decarboxylase YP_882590.1 3553552 R 243243 CDS YP_882591.1 118462241 4526926 complement(3556501..3556890) 1 NC_008595.1 N utilization substance protein B 3556890 4526926 MAV_3409 Mycobacterium avium 104 N utilization substance protein B YP_882591.1 3556501 R 243243 CDS YP_882592.1 118463415 4530052 complement(3556887..3557357) 1 NC_008595.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 3557357 nusB 4530052 nusB Mycobacterium avium 104 transcription antitermination protein NusB YP_882592.1 3556887 R 243243 CDS YP_882593.1 118467065 4526443 complement(3557354..3557917) 1 NC_008595.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 3557917 efp 4526443 efp Mycobacterium avium 104 elongation factor P YP_882593.1 3557354 R 243243 CDS YP_882594.1 118465414 4529963 complement(3558005..3559114) 1 NC_008595.1 identified by match to protein family HMM PF00557; peptidase, M24 family protein 3559114 4529963 MAV_3412 Mycobacterium avium 104 peptidase, M24 family protein YP_882594.1 3558005 R 243243 CDS YP_882595.1 118465973 4528192 3559160..3559819 1 NC_008595.1 hypothetical protein 3559819 4528192 MAV_3414 Mycobacterium avium 104 hypothetical protein YP_882595.1 3559160 D 243243 CDS YP_882596.1 118463627 4527331 complement(3559816..3560247) 1 NC_008595.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 3560247 aroQ 4527331 aroQ Mycobacterium avium 104 3-dehydroquinate dehydratase YP_882596.1 3559816 R 243243 CDS YP_882597.1 118464192 4529303 complement(3560244..3561320) 1 NC_008595.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3561320 aroB 4529303 aroB Mycobacterium avium 104 3-dehydroquinate synthase YP_882597.1 3560244 R 243243 CDS YP_882598.1 118462476 4528730 complement(3561338..3561868) 1 NC_008595.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 3561868 aroK 4528730 aroK Mycobacterium avium 104 shikimate kinase YP_882598.1 3561338 R 243243 CDS YP_882599.1 118464231 4528604 complement(3561868..3563073) 1 NC_008595.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3563073 aroC 4528604 aroC Mycobacterium avium 104 chorismate synthase YP_882599.1 3561868 R 243243 CDS YP_882600.1 118462510 4528588 complement(3563131..3564738) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3564738 4528588 MAV_3418 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_882600.1 3563131 R 243243 CDS YP_882601.1 118463075 4527574 complement(3564757..3565563) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 3565563 4527574 MAV_3419 Mycobacterium avium 104 ABC transporter permease YP_882601.1 3564757 R 243243 CDS YP_882602.1 118467138 4527151 complement(3565560..3566522) 1 NC_008595.1 identified by match to protein family HMM PF00528; ABC transporter permease 3566522 4527151 MAV_3420 Mycobacterium avium 104 ABC transporter permease YP_882602.1 3565560 R 243243 CDS YP_882603.1 118464566 4530785 complement(3566528..3568120) 1 NC_008595.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein, family protein 5 3568120 4530785 MAV_3421 Mycobacterium avium 104 extracellular solute-binding protein, family protein 5 YP_882603.1 3566528 R 243243 CDS YP_882604.1 118465640 4526165 complement(3568130..3569341) 1 NC_008595.1 identified by match to protein family HMM PF08028; acyl-CoA dehydrogenase domain-containing protein 3569341 4526165 MAV_3422 Mycobacterium avium 104 acyl-CoA dehydrogenase domain-containing protein YP_882604.1 3568130 R 243243 CDS YP_882605.1 118464286 4529574 3569324..3570085 1 NC_008595.1 hypothetical protein 3570085 4529574 MAV_3423 Mycobacterium avium 104 hypothetical protein YP_882605.1 3569324 D 243243 CDS YP_882606.1 118463521 4526826 3570088..3570468 1 NC_008595.1 hypothetical protein 3570468 4526826 MAV_3424 Mycobacterium avium 104 hypothetical protein YP_882606.1 3570088 D 243243 CDS YP_882607.1 118466489 4527619 3570465..3571745 1 NC_008595.1 identified by match to protein family HMM PF00296; nitrilotriacetate monooxygenase component A 3571745 4527619 MAV_3425 Mycobacterium avium 104 nitrilotriacetate monooxygenase component A YP_882607.1 3570465 D 243243 CDS YP_882608.1 118466711 4529718 3571767..3572852 1 NC_008595.1 identified by match to protein family HMM PF00296; alkanesulfonate monooxygenase 3572852 4529718 MAV_3426 Mycobacterium avium 104 alkanesulfonate monooxygenase YP_882608.1 3571767 D 243243 CDS YP_882609.1 118462509 4528587 complement(3572859..3573287) 1 NC_008595.1 identified by match to protein family HMM PF01478; peptidase, A24 (type IV prepilin peptidase) family protein 3573287 4528587 MAV_3427 Mycobacterium avium 104 peptidase, A24 (type IV prepilin peptidase) family protein YP_882609.1 3572859 R 243243 CDS YP_882610.2 229220809 4526267 complement(3573298..3574182) 1 NC_008595.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3574182 aroE 4526267 aroE Mycobacterium avium 104 shikimate 5-dehydrogenase YP_882610.2 3573298 R 243243 CDS YP_882611.1 118465683 4525742 complement(3574157..3575404) 1 NC_008595.1 identified by match to protein family HMM PF02618; hypothetical protein 3575404 4525742 MAV_3429 Mycobacterium avium 104 hypothetical protein YP_882611.1 3574157 R 243243 CDS YP_882612.1 118466058 4530028 complement(3575397..3575894) 1 NC_008595.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3575894 4530028 MAV_3430 Mycobacterium avium 104 Holliday junction resolvase-like protein YP_882612.1 3575397 R 243243 CDS YP_882613.1 118466707 4529714 complement(3575901..3578603) 1 NC_008595.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3578603 alaS 4529714 alaS Mycobacterium avium 104 alanyl-tRNA synthetase YP_882613.1 3575901 R 243243 CDS YP_882614.1 118462669 4529097 complement(3578687..3579088) 1 NC_008595.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 3579088 4529097 MAV_3432 Mycobacterium avium 104 hypothetical protein YP_882614.1 3578687 R 243243 CDS YP_882615.1 118464884 4529613 3579242..3579865 1 NC_008595.1 hypothetical protein 3579865 4529613 MAV_3433 Mycobacterium avium 104 hypothetical protein YP_882615.1 3579242 D 243243 CDS YP_882616.1 118465107 4529998 complement(3579940..3580275) 1 NC_008595.1 hypothetical protein 3580275 4529998 MAV_3434 Mycobacterium avium 104 hypothetical protein YP_882616.1 3579940 R 243243 CDS YP_882617.1 118466446 4527119 complement(3580272..3581612) 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF07728; recombination factor protein RarA 3581612 4527119 MAV_3435 Mycobacterium avium 104 recombination factor protein RarA YP_882617.1 3580272 R 243243 CDS YP_882618.1 118466180 4526211 3581771..3582748 1 NC_008595.1 hypothetical protein 3582748 4526211 MAV_3436 Mycobacterium avium 104 hypothetical protein YP_882618.1 3581771 D 243243 CDS YP_882619.1 118463026 4528867 3582819..3585482 1 NC_008595.1 identified by match to protein family HMM PF04168; match to protein family HMM PF04169; match to protein family HMM PF04174; hypothetical protein 3585482 4528867 MAV_3438 Mycobacterium avium 104 hypothetical protein YP_882619.1 3582819 D 243243 CDS YP_882620.1 118463725 4528075 complement(3585479..3586501) 1 NC_008595.1 hypothetical protein 3586501 4528075 MAV_3437 Mycobacterium avium 104 hypothetical protein YP_882620.1 3585479 R 243243 CDS YP_882621.1 118462994 4530624 complement(3586494..3587417) 1 NC_008595.1 identified by match to protein family HMM PF01841; transglutaminase 3587417 4530624 MAV_3439 Mycobacterium avium 104 transglutaminase YP_882621.1 3586494 R 243243 CDS YP_882622.1 118467090 4526390 3587519..3587908 1 NC_008595.1 identified by match to protein family HMM PF04944; hypothetical protein 3587908 4526390 MAV_3440 Mycobacterium avium 104 hypothetical protein YP_882622.1 3587519 D 243243 CDS YP_882623.1 118466958 4530270 complement(3587914..3588972) 1 NC_008595.1 hypothetical protein 3588972 4530270 MAV_3441 Mycobacterium avium 104 hypothetical protein YP_882623.1 3587914 R 243243 CDS YP_882624.1 118465999 4528443 complement(3588976..3589407) 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 3589407 4528443 MAV_3442 Mycobacterium avium 104 hypothetical protein YP_882624.1 3588976 R 243243 CDS YP_882625.1 118464612 4526769 complement(3589694..3590416) 1 NC_008595.1 hypothetical protein 3590416 4526769 MAV_3443 Mycobacterium avium 104 hypothetical protein YP_882625.1 3589694 R 243243 CDS YP_882626.1 118465564 4526750 complement(3590416..3590982) 1 NC_008595.1 hypothetical protein 3590982 4526750 MAV_3444 Mycobacterium avium 104 hypothetical protein YP_882626.1 3590416 R 243243 CDS YP_882627.1 118463790 4525871 complement(3590993..3591916) 1 NC_008595.1 hypothetical protein 3591916 4525871 MAV_3445 Mycobacterium avium 104 hypothetical protein YP_882627.1 3590993 R 243243 CDS YP_882628.1 118464197 4529308 complement(3592206..3592313) 1 NC_008595.1 hypothetical protein 3592313 4529308 MAV_3446 Mycobacterium avium 104 hypothetical protein YP_882628.1 3592206 R 243243 CDS YP_882629.1 118462335 4525680 complement(3592533..3594308) 1 NC_008595.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 3594308 aspS 4525680 aspS Mycobacterium avium 104 aspartyl-tRNA synthetase YP_882629.1 3592533 R 243243 CDS YP_882630.1 118466556 4529105 3594452..3595255 1 NC_008595.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 3595255 4529105 MAV_3448 Mycobacterium avium 104 2-dehydropantoate 2-reductase YP_882630.1 3594452 D 243243 CDS YP_882631.1 118466547 4527015 3595265..3595762 1 NC_008595.1 hypothetical protein 3595762 4527015 MAV_3449 Mycobacterium avium 104 hypothetical protein YP_882631.1 3595265 D 243243 CDS YP_882632.1 118467327 4526965 3595772..3596650 1 NC_008595.1 identified by match to protein family HMM PF04228; metallopeptidase, zinc binding 3596650 4526965 MAV_3451 Mycobacterium avium 104 metallopeptidase, zinc binding YP_882632.1 3595772 D 243243 CDS YP_882633.1 118465168 4528658 complement(3596647..3597522) 1 NC_008595.1 identified by match to protein family HMM PF00701; dihydrodipicolinate synthetase 3597522 4528658 MAV_3450 Mycobacterium avium 104 dihydrodipicolinate synthetase YP_882633.1 3596647 R 243243 CDS YP_882634.1 118465864 4527506 complement(3597534..3598331) 1 NC_008595.1 identified by match to protein family HMM PF00596; class II aldolase/adducin domain protein 3598331 4527506 MAV_3452 Mycobacterium avium 104 class II aldolase/adducin domain protein YP_882634.1 3597534 R 243243 CDS YP_882635.1 118463045 4528324 3598378..3598914 1 NC_008595.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; transcriptional regulator 3598914 4528324 MAV_3453 Mycobacterium avium 104 transcriptional regulator YP_882635.1 3598378 D 243243 CDS YP_882636.1 118463299 4525994 complement(3598915..3599298) 1 NC_008595.1 hypothetical protein 3599298 4525994 MAV_3454 Mycobacterium avium 104 hypothetical protein YP_882636.1 3598915 R 243243 CDS YP_882637.1 118463149 4527787 3599426..3601036 1 NC_008595.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR01409; metallophosphoesterase 3601036 4527787 MAV_3455 Mycobacterium avium 104 metallophosphoesterase YP_882637.1 3599426 D 243243 CDS YP_882638.1 118466152 4528774 complement(3601067..3602095) 1 NC_008595.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 3602095 4528774 MAV_3456 Mycobacterium avium 104 radical SAM domain-containing protein YP_882638.1 3601067 R 243243 CDS YP_882639.1 118466571 4527360 complement(3602144..3603613) 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 3603613 4527360 MAV_3457 Mycobacterium avium 104 hypothetical protein YP_882639.1 3602144 R 243243 CDS YP_882640.1 118462947 4530232 3603678..3604037 1 NC_008595.1 transposase 3604037 4530232 MAV_3458 Mycobacterium avium 104 transposase YP_882640.1 3603678 D 243243 CDS YP_882641.1 118467295 4527253 complement(3604448..3604921) 1 NC_008595.1 hypothetical protein 3604921 4527253 MAV_3459 Mycobacterium avium 104 hypothetical protein YP_882641.1 3604448 R 243243 CDS YP_882642.1 118466054 4530024 complement(3605150..3606412) 1 NC_008595.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 3606412 hisS 4530024 hisS Mycobacterium avium 104 histidyl-tRNA synthetase YP_882642.1 3605150 R 243243 CDS YP_882643.1 118463945 4526597 complement(3606416..3607072) 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 3607072 4526597 MAV_3461 Mycobacterium avium 104 metallo-beta-lactamase YP_882643.1 3606416 R 243243 CDS YP_882644.1 118464361 4530504 3607182..3608069 1 NC_008595.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase, cyclophilin-type 3608069 4530504 MAV_3462 Mycobacterium avium 104 peptidyl-prolyl cis-trans isomerase, cyclophilin-type YP_882644.1 3607182 D 243243 CDS YP_882645.1 118462481 4530677 3608100..3609752 1 NC_008595.1 identified by match to protein family HMM PF00069; match to protein family HMM PF00160; protein kinase/peptidyl-prolyl cis-trans isomerase, cyclophilin-type 3609752 4530677 MAV_3463 Mycobacterium avium 104 protein kinase/peptidyl-prolyl cis-trans isomerase, cyclophilin-type YP_882645.1 3608100 D 243243 CDS YP_882646.1 118467123 4526150 complement(3609756..3612131) 1 NC_008595.1 identified by similarity to SP:P52560; match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 3612131 relA 4526150 relA Mycobacterium avium 104 GTP pyrophosphokinase YP_882646.1 3609756 R 243243 CDS YP_882647.1 118466559 4529108 complement(3612166..3612708) 1 NC_008595.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 3612708 4529108 MAV_3465 Mycobacterium avium 104 adenine phosphoribosyltransferase YP_882647.1 3612166 R 243243 CDS YP_882648.1 118462505 4528583 complement(3612716..3614389) 1 NC_008595.1 identified by match to protein family HMM PF00496; extracellular solute-binding protein, family protein 5 3614389 4528583 MAV_3466 Mycobacterium avium 104 extracellular solute-binding protein, family protein 5 YP_882648.1 3612716 R 243243 CDS YP_882649.1 118462611 4528515 complement(3614394..3615701) 1 NC_008595.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 3615701 secF 4528515 secF Mycobacterium avium 104 preprotein translocase subunit SecF YP_882649.1 3614394 R 243243 CDS YP_882650.1 118463542 4526809 complement(3615704..3617530) 1 NC_008595.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 3617530 secD 4526809 secD Mycobacterium avium 104 preprotein translocase subunit SecD YP_882650.1 3615704 R 243243 CDS YP_882651.1 118464311 4526641 complement(3617654..3617986) 1 NC_008595.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 3617986 yajC 4526641 yajC Mycobacterium avium 104 preprotein translocase subunit YajC YP_882651.1 3617654 R 243243 CDS YP_882652.1 118462719 4530093 3618144..3619493 1 NC_008595.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3619493 gabT 4530093 gabT Mycobacterium avium 104 4-aminobutyrate aminotransferase YP_882652.1 3618144 D 243243 CDS YP_882653.1 118463274 4530522 3619656..3623177 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01746; acyl-CoA dehydrogenase 3623177 4530522 MAV_3471 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882653.1 3619656 D 243243 CDS YP_882654.1 118463530 4526835 complement(3623243..3623920) 1 NC_008595.1 hypothetical protein 3623920 4526835 MAV_3472 Mycobacterium avium 104 hypothetical protein YP_882654.1 3623243 R 243243 CDS YP_882655.1 118464703 4527892 complement(3624400..3625455) 1 NC_008595.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 3625455 ruvB 4527892 ruvB Mycobacterium avium 104 Holliday junction DNA helicase RuvB YP_882655.1 3624400 R 243243 CDS YP_882656.1 118465009 4526275 complement(3625505..3626104) 1 NC_008595.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 3626104 ruvA 4526275 ruvA Mycobacterium avium 104 Holliday junction DNA helicase RuvA YP_882656.1 3625505 R 243243 CDS YP_882657.1 118464158 4526468 complement(3626101..3626667) 1 NC_008595.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 3626667 ruvC 4526468 ruvC Mycobacterium avium 104 Holliday junction resolvase YP_882657.1 3626101 R 243243 CDS YP_882658.1 118464642 4528977 3626849..3627460 1 NC_008595.1 hypothetical protein 3627460 4528977 MAV_3476 Mycobacterium avium 104 hypothetical protein YP_882658.1 3626849 D 243243 CDS YP_882659.1 118463742 4528150 3627432..3627983 1 NC_008595.1 hypothetical protein 3627983 4528150 MAV_3477 Mycobacterium avium 104 hypothetical protein YP_882659.1 3627432 D 243243 CDS YP_882660.1 118465773 4526908 3627980..3628411 1 NC_008595.1 hypothetical protein 3628411 4526908 MAV_3478 Mycobacterium avium 104 hypothetical protein YP_882660.1 3627980 D 243243 CDS YP_882661.1 118465264 4527285 3628456..3628911 1 NC_008595.1 identified by match to protein family HMM PF03994; hypothetical protein 3628911 4527285 MAV_3479 Mycobacterium avium 104 hypothetical protein YP_882661.1 3628456 D 243243 CDS YP_882662.1 118464595 4530106 3628908..3630479 1 NC_008595.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3630479 4530106 MAV_3480 Mycobacterium avium 104 spermidine synthase YP_882662.1 3628908 D 243243 CDS YP_882663.1 118464014 4528810 complement(3630490..3631242) 1 NC_008595.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 3631242 4528810 MAV_3481 Mycobacterium avium 104 hypothetical protein YP_882663.1 3630490 R 243243 CDS YP_882664.1 118465637 4526162 complement(3631370..3631966) 1 NC_008595.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 3631966 4526162 MAV_3482 Mycobacterium avium 104 glutamine amidotransferase subunit PdxT YP_882664.1 3631370 R 243243 CDS YP_882665.1 118465089 4525906 complement(3631963..3632799) 1 NC_008595.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase II 3632799 tesB 4525906 tesB Mycobacterium avium 104 acyl-CoA thioesterase II YP_882665.1 3631963 R 243243 CDS YP_882666.1 118466215 4528894 complement(3632809..3633720) 1 NC_008595.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 3633720 4528894 MAV_3484 Mycobacterium avium 104 pyridoxal biosynthesis lyase PdxS YP_882666.1 3632809 R 243243 CDS YP_882667.1 118463178 4527701 complement(3633790..3634818) 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, nudix family protein 3634818 4527701 MAV_3485 Mycobacterium avium 104 hydrolase, nudix family protein YP_882667.1 3633790 R 243243 CDS YP_882668.1 118465207 4529844 complement(3634815..3635939) 1 NC_008595.1 identified by match to protein family HMM PF00534; phosphatidylinositol alpha-mannosyltransferase 3635939 4529844 MAV_3486 Mycobacterium avium 104 phosphatidylinositol alpha-mannosyltransferase YP_882668.1 3634815 R 243243 CDS YP_882669.1 118464398 4530792 complement(3635939..3636901) 1 NC_008595.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 3636901 4530792 MAV_3487 Mycobacterium avium 104 lipid A biosynthesis lauroyl acyltransferase YP_882669.1 3635939 R 243243 CDS YP_882670.1 118466345 4530485 complement(3636898..3637539) 1 NC_008595.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 3637539 4530485 MAV_3488 Mycobacterium avium 104 CDP-alcohol phosphatidyltransferase YP_882670.1 3636898 R 243243 CDS YP_882671.1 118465447 4527316 complement(3637552..3638136) 1 NC_008595.1 identified by match to protein family HMM PF01230; diadenosine tetraphosphate 3638136 4527316 MAV_3489 Mycobacterium avium 104 diadenosine tetraphosphate YP_882671.1 3637552 R 243243 CDS YP_882672.1 118462301 4525646 complement(3638129..3640183) 1 NC_008595.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 3640183 thrS 4525646 thrS Mycobacterium avium 104 threonyl-tRNA synthetase YP_882672.1 3638129 R 243243 CDS YP_882673.1 118462710 4530084 3640282..3641943 1 NC_008595.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 3641943 4530084 MAV_3491 Mycobacterium avium 104 Na+/H+ antiporter YP_882673.1 3640282 D 243243 CDS YP_882674.1 118464743 4529430 complement(3641990..3643234) 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; N-alpha-acyl-glutamine aminoacylase 3643234 4529430 MAV_3492 Mycobacterium avium 104 N-alpha-acyl-glutamine aminoacylase YP_882674.1 3641990 R 243243 CDS YP_882675.1 118464000 4529262 complement(3643287..3643913) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 3643913 4529262 MAV_3493 Mycobacterium avium 104 thioesterase YP_882675.1 3643287 R 243243 CDS YP_882676.1 118463315 4529555 complement(3643950..3644828) 1 NC_008595.1 identified by match to protein family HMM PF00248; oxidoreductase YdbC 3644828 4529555 MAV_3494 Mycobacterium avium 104 oxidoreductase YdbC YP_882676.1 3643950 R 243243 CDS YP_882677.1 118463358 4529892 3644886..3645386 1 NC_008595.1 hypothetical protein 3645386 4529892 MAV_3495 Mycobacterium avium 104 hypothetical protein YP_882677.1 3644886 D 243243 CDS YP_882678.1 118465420 4529969 complement(3645483..3646424) 1 NC_008595.1 identified by match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 3646424 4529969 MAV_3496 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_882678.1 3645483 R 243243 CDS YP_882679.1 118464622 4526779 complement(3646431..3646775) 1 NC_008595.1 identified by match to protein family HMM PF07883; cupin domain-containing protein 3646775 4526779 MAV_3497 Mycobacterium avium 104 cupin domain-containing protein YP_882679.1 3646431 R 243243 CDS YP_882680.1 118466245 4526864 complement(3646823..3647248) 1 NC_008595.1 hypothetical protein 3647248 4526864 MAV_3498 Mycobacterium avium 104 hypothetical protein YP_882680.1 3646823 R 243243 CDS YP_882681.1 118465695 4530317 complement(3647245..3647949) 1 NC_008595.1 hypothetical protein 3647949 4530317 MAV_3499 Mycobacterium avium 104 hypothetical protein YP_882681.1 3647245 R 243243 CDS YP_882682.1 118462225 4525562 complement(3647962..3648318) 1 NC_008595.1 identified by match to protein family HMM PF00037; ferredoxin FdxA 3648318 4525562 MAV_3500 Mycobacterium avium 104 ferredoxin FdxA YP_882682.1 3647962 R 243243 CDS YP_882683.1 118466822 4527387 3648375..3649220 1 NC_008595.1 SAM-dependent methyltransferase 3649220 4527387 MAV_3501 Mycobacterium avium 104 SAM-dependent methyltransferase YP_882683.1 3648375 D 243243 CDS YP_882684.1 118463385 4528963 3649345..3649557 1 NC_008595.1 hypothetical protein 3649557 4528963 MAV_3502 Mycobacterium avium 104 hypothetical protein YP_882684.1 3649345 D 243243 CDS YP_882685.1 118462821 4529041 3649741..3650004 1 NC_008595.1 hypothetical protein 3650004 4529041 MAV_3503 Mycobacterium avium 104 hypothetical protein YP_882685.1 3649741 D 243243 CDS YP_882686.1 118466955 4530267 complement(3650018..3651244) 1 NC_008595.1 identified by match to protein family HMM PF00206; match to protein family HMM TIGR02426; 3-carboxy-cis,cis-muconate cycloisomerase 3651244 pcaB 4530267 pcaB Mycobacterium avium 104 3-carboxy-cis,cis-muconate cycloisomerase YP_882686.1 3650018 R 243243 CDS YP_882687.1 118466459 4528680 complement(3651241..3651747) 1 NC_008595.1 identified by match to protein family HMM PF00775; match to protein family HMM TIGR02423; protocatechuate 3,4-dioxygenase, alpha subunit 3651747 pcaG 4528680 pcaG Mycobacterium avium 104 protocatechuate 3,4-dioxygenase, alpha subunit YP_882687.1 3651241 R 243243 CDS YP_882688.1 118464793 4526717 complement(3651797..3652561) 1 NC_008595.1 identified by match to protein family HMM PF00775; match to protein family HMM TIGR02422; protocatechuate 3,4-dioxygenase, beta subunit 3652561 pcaH 4526717 pcaH Mycobacterium avium 104 protocatechuate 3,4-dioxygenase, beta subunit YP_882688.1 3651797 R 243243 CDS YP_882689.1 118462263 4526406 complement(3652629..3653114) 1 NC_008595.1 identified by match to protein family HMM PF01814; hemerythrin HHE cation binding domain-containing protein 3653114 4526406 MAV_3507 Mycobacterium avium 104 hemerythrin HHE cation binding domain-containing protein YP_882689.1 3652629 R 243243 CDS YP_882690.1 118465283 4529319 complement(3653111..3654082) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 3654082 4529319 MAV_3508 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_882690.1 3653111 R 243243 CDS YP_882691.1 118463608 4527555 3654352..3655713 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM PF00848; phthalate dioxygenase large subunit 3655713 4527555 MAV_3509 Mycobacterium avium 104 phthalate dioxygenase large subunit YP_882691.1 3654352 D 243243 CDS YP_882692.1 118464165 4526475 3655698..3656222 1 NC_008595.1 identified by match to protein family HMM PF00866; 3-phenylpropionate dioxygenase subunit beta 3656222 4526475 MAV_3510 Mycobacterium avium 104 3-phenylpropionate dioxygenase subunit beta YP_882692.1 3655698 D 243243 CDS YP_882693.1 118465135 4529166 3656219..3656470 1 NC_008595.1 dihydrodiol dehydrogenase 3656470 4529166 MAV_3511 Mycobacterium avium 104 dihydrodiol dehydrogenase YP_882693.1 3656219 D 243243 CDS YP_882694.1 118464452 4525983 3656454..3657248 1 NC_008595.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 3657248 4525983 MAV_3512 Mycobacterium avium 104 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_882694.1 3656454 D 243243 CDS YP_882695.1 118464441 4525972 3657245..3657967 1 NC_008595.1 identified by match to protein family HMM PF00596; FliH protein 3657967 4525972 MAV_3514 Mycobacterium avium 104 FliH protein YP_882695.1 3657245 D 243243 CDS YP_882696.1 118462389 4525932 complement(3657964..3658779) 1 NC_008595.1 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 3658779 4525932 MAV_3513 Mycobacterium avium 104 IclR family transcriptional regulator YP_882696.1 3657964 R 243243 CDS YP_882697.1 118466670 4526620 3658830..3659636 1 NC_008595.1 identified by match to protein family HMM PF00657; hypothetical protein 3659636 4526620 MAV_3515 Mycobacterium avium 104 hypothetical protein YP_882697.1 3658830 D 243243 CDS YP_882698.1 118464719 4529406 3659684..3660298 1 NC_008595.1 integral membrane protein 3660298 4529406 MAV_3516 Mycobacterium avium 104 integral membrane protein YP_882698.1 3659684 D 243243 CDS YP_882699.1 118464172 4526482 complement(3660299..3660916) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3660916 4526482 MAV_3517 Mycobacterium avium 104 TetR family transcriptional regulator YP_882699.1 3660299 R 243243 CDS YP_882700.1 118462259 4526402 3661086..3661508 1 NC_008595.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; anti-anti-sigma factor 3661508 4526402 MAV_3518 Mycobacterium avium 104 anti-anti-sigma factor YP_882700.1 3661086 D 243243 CDS YP_882701.1 118463145 4527783 complement(3661551..3662321) 1 NC_008595.1 identified by match to protein family HMM PF01925; hypothetical protein 3662321 4527783 MAV_3519 Mycobacterium avium 104 hypothetical protein YP_882701.1 3661551 R 243243 CDS YP_882702.1 118463626 4527330 complement(3662390..3663331) 1 NC_008595.1 identified by match to protein family HMM PF00199; catalase 3663331 4527330 MAV_3520 Mycobacterium avium 104 catalase YP_882702.1 3662390 R 243243 CDS YP_882703.1 118464156 4526466 complement(3663367..3664167) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 3664167 4526466 MAV_3521 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_882703.1 3663367 R 243243 CDS YP_882704.1 118462644 4529385 3664477..3664950 1 NC_008595.1 hypothetical protein 3664950 4529385 MAV_3522 Mycobacterium avium 104 hypothetical protein YP_882704.1 3664477 D 243243 CDS YP_882705.1 118463036 4528877 3665036..3666583 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA synthase 3666583 4528877 MAV_3523 Mycobacterium avium 104 acyl-CoA synthase YP_882705.1 3665036 D 243243 CDS YP_882706.1 118466695 4530437 complement(3666587..3667423) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 3667423 4530437 MAV_3524 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_882706.1 3666587 R 243243 CDS YP_882707.1 118463904 4525835 complement(3667512..3667805) 1 NC_008595.1 hypothetical protein 3667805 4525835 MAV_3525 Mycobacterium avium 104 hypothetical protein YP_882707.1 3667512 R 243243 CDS YP_882708.1 118463491 4529070 complement(3667826..3668224) 1 NC_008595.1 hypothetical protein 3668224 4529070 MAV_3526 Mycobacterium avium 104 hypothetical protein YP_882708.1 3667826 R 243243 CDS YP_882709.1 118465090 4525907 3668967..3669305 1 NC_008595.1 hypothetical protein 3669305 4525907 MAV_3531 Mycobacterium avium 104 hypothetical protein YP_882709.1 3668967 D 243243 CDS YP_882710.1 118464360 4530503 complement(3670518..3671312) 1 NC_008595.1 identified by match to protein family HMM PF01695; helper protein 3671312 4530503 MAV_3532 Mycobacterium avium 104 helper protein YP_882710.1 3670518 R 243243 CDS YP_882711.1 118466182 4526213 complement(3671309..3672787) 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 3672787 4526213 MAV_3533 Mycobacterium avium 104 transposase YP_882711.1 3671309 R 243243 CDS YP_882712.1 118465448 4527317 3672840..3673037 1 NC_008595.1 hypothetical protein 3673037 4527317 MAV_3534 Mycobacterium avium 104 hypothetical protein YP_882712.1 3672840 D 243243 CDS YP_882713.1 118465462 4526230 3673068..3674393 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3674393 4526230 MAV_3535 Mycobacterium avium 104 transposase, Mutator family protein YP_882713.1 3673068 D 243243 CDS YP_882714.1 118463467 4525520 3674454..3675686 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3675686 4525520 MAV_3536 Mycobacterium avium 104 transposase, Mutator family protein YP_882714.1 3674454 D 243243 CDS YP_882715.1 118464966 4528706 3675779..3676078 1 NC_008595.1 hypothetical protein 3676078 4528706 MAV_3537 Mycobacterium avium 104 hypothetical protein YP_882715.1 3675779 D 243243 CDS YP_882716.1 118462746 4527836 3676276..3676584 1 NC_008595.1 hypothetical protein 3676584 4527836 MAV_3538 Mycobacterium avium 104 hypothetical protein YP_882716.1 3676276 D 243243 CDS YP_882717.1 118464415 4530236 3676661..3677182 1 NC_008595.1 hypothetical protein 3677182 4530236 MAV_3539 Mycobacterium avium 104 hypothetical protein YP_882717.1 3676661 D 243243 CDS YP_882718.1 118463693 4530580 complement(3677190..3678467) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 3678467 4530580 MAV_3540 Mycobacterium avium 104 amidohydrolase YP_882718.1 3677190 R 243243 CDS YP_882719.1 118463931 4528111 complement(3678482..3679696) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 3679696 4528111 MAV_3541 Mycobacterium avium 104 amidohydrolase YP_882719.1 3678482 R 243243 CDS YP_882720.1 118463021 4526314 complement(3679700..3680503) 1 NC_008595.1 identified by match to protein family HMM PF06314; acetoacetate decarboxylase 3680503 4526314 MAV_3542 Mycobacterium avium 104 acetoacetate decarboxylase YP_882720.1 3679700 R 243243 CDS YP_882721.1 118465757 4530450 complement(3680500..3681438) 1 NC_008595.1 probable dehydrogenase; hypothetical protein 3681438 4530450 MAV_3543 Mycobacterium avium 104 hypothetical protein YP_882721.1 3680500 R 243243 CDS YP_882722.1 118465243 4528461 3681437..3682390 1 NC_008595.1 hypothetical protein 3682390 4528461 MAV_3545 Mycobacterium avium 104 hypothetical protein YP_882722.1 3681437 D 243243 CDS YP_882723.1 118467203 4528437 complement(3682387..3683661) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 3683661 4528437 MAV_3544 Mycobacterium avium 104 amidohydrolase YP_882723.1 3682387 R 243243 CDS YP_882724.1 118465530 4530003 3683751..3683969 1 NC_008595.1 hypothetical protein 3683969 4530003 MAV_3546 Mycobacterium avium 104 hypothetical protein YP_882724.1 3683751 D 243243 CDS YP_882725.1 118463011 4526304 3684043..3684420 1 NC_008595.1 hypothetical protein 3684420 4526304 MAV_3547 Mycobacterium avium 104 hypothetical protein YP_882725.1 3684043 D 243243 CDS YP_882726.1 118464468 4527061 3684516..3684887 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 3684887 4527061 MAV_3549 Mycobacterium avium 104 hypothetical protein YP_882726.1 3684516 D 243243 CDS YP_882727.1 118462285 4529290 complement(3684818..3685486) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3685486 4529290 MAV_3548 Mycobacterium avium 104 TetR family transcriptional regulator YP_882727.1 3684818 R 243243 CDS YP_882728.1 118463724 4528074 3685572..3686402 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 3686402 4528074 MAV_3550 Mycobacterium avium 104 short chain dehydrogenase YP_882728.1 3685572 D 243243 CDS YP_882729.1 118463983 4530341 3686404..3687225 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 3687225 4530341 MAV_3551 Mycobacterium avium 104 carveol dehydrogenase YP_882729.1 3686404 D 243243 CDS YP_882730.1 118463997 4529259 3687209..3688024 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 3688024 pcaC 4529259 pcaC Mycobacterium avium 104 hypothetical protein YP_882730.1 3687209 D 243243 CDS YP_882731.1 118464742 4529429 3688028..3689491 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 3689491 4529429 MAV_3553 Mycobacterium avium 104 aldehyde dehydrogenase YP_882731.1 3688028 D 243243 CDS YP_882732.1 118462729 4527800 3689588..3689800 1 NC_008595.1 hypothetical protein 3689800 4527800 MAV_3554 Mycobacterium avium 104 hypothetical protein YP_882732.1 3689588 D 243243 CDS YP_882733.1 118466177 4526208 3689967..3690887 1 NC_008595.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 3690887 4526208 MAV_3555 Mycobacterium avium 104 cation efflux family protein YP_882733.1 3689967 D 243243 CDS YP_882734.1 118465053 4527029 complement(3690918..3691847) 1 NC_008595.1 copper resistance D, putative 3691847 4527029 MAV_3556 Mycobacterium avium 104 copper resistance D, putative YP_882734.1 3690918 R 243243 CDS YP_882735.1 118465355 4526668 complement(3691876..3692220) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 3692220 4526668 MAV_3557 Mycobacterium avium 104 hypothetical protein YP_882735.1 3691876 R 243243 CDS YP_882736.1 118466065 4530035 complement(3692418..3692786) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 3692786 4530035 MAV_3558 Mycobacterium avium 104 hypothetical protein YP_882736.1 3692418 R 243243 CDS YP_882737.1 118463869 4527747 3692886..3693638 1 NC_008595.1 identified by match to protein family HMM PF02861; ATP-dependent Clp protease ATP-binding subunit 3693638 4527747 MAV_3559 Mycobacterium avium 104 ATP-dependent Clp protease ATP-binding subunit YP_882737.1 3692886 D 243243 CDS YP_882738.1 118462560 4528619 3693813..3694205 1 NC_008595.1 hypothetical protein 3694205 4528619 MAV_3560 Mycobacterium avium 104 hypothetical protein YP_882738.1 3693813 D 243243 CDS YP_882739.1 118463552 4526819 3694193..3694723 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 3694723 4526819 MAV_3562 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_882739.1 3694193 D 243243 CDS YP_882740.1 118464282 4529570 complement(3694701..3695786) 1 NC_008595.1 identified by match to protein family HMM PF03969; ATP/GTP-binding integral membrane protein 3695786 4529570 MAV_3561 Mycobacterium avium 104 ATP/GTP-binding integral membrane protein YP_882740.1 3694701 R 243243 CDS YP_882741.1 118463485 4529063 3695821..3696585 1 NC_008595.1 identified by match to protein family HMM PF01872; hypothetical protein 3696585 4529063 MAV_3563 Mycobacterium avium 104 hypothetical protein YP_882741.1 3695821 D 243243 CDS YP_882742.1 118467178 4530148 3696591..3698159 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 3698159 4530148 MAV_3564 Mycobacterium avium 104 alpha/beta hydrolase YP_882742.1 3696591 D 243243 CDS YP_882743.1 118466550 4529099 3698188..3699474 1 NC_008595.1 hypothetical protein 3699474 4529099 MAV_3565 Mycobacterium avium 104 hypothetical protein YP_882743.1 3698188 D 243243 CDS YP_882744.1 118466366 4529928 3699819..3700223 1 NC_008595.1 identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; methionine-R-sulfoxide reductase 3700223 msrB 4529928 msrB Mycobacterium avium 104 methionine-R-sulfoxide reductase YP_882744.1 3699819 D 243243 CDS YP_882745.1 118465201 4530398 3700372..3700893 1 NC_008595.1 hypothetical protein 3700893 4530398 MAV_3567 Mycobacterium avium 104 hypothetical protein YP_882745.1 3700372 D 243243 CDS YP_882746.1 118464364 4530507 complement(3700932..3702206) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3702206 4530507 MAV_3568 Mycobacterium avium 104 transposase, Mutator family protein YP_882746.1 3700932 R 243243 CDS YP_882747.1 118463743 4528151 3702293..3702628 1 NC_008595.1 hypothetical protein 3702628 4528151 MAV_3569 Mycobacterium avium 104 hypothetical protein YP_882747.1 3702293 D 243243 CDS YP_882748.1 118463475 4525528 complement(3702695..3703447) 1 NC_008595.1 identified by match to protein family HMM PF05724; thiopurine S-methyltransferase (tpmt) superfamily protein 3703447 4525528 MAV_3570 Mycobacterium avium 104 thiopurine S-methyltransferase (tpmt) superfamily protein YP_882748.1 3702695 R 243243 CDS YP_882749.1 118467135 4527148 complement(3703444..3704139) 1 NC_008595.1 identified by match to protein family HMM PF06778; hypothetical protein 3704139 4527148 MAV_3571 Mycobacterium avium 104 hypothetical protein YP_882749.1 3703444 R 243243 CDS YP_882750.1 118466726 4530664 complement(3705498..3706571) 1 NC_008595.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 3706571 hemE 4530664 hemE Mycobacterium avium 104 uroporphyrinogen decarboxylase YP_882750.1 3705498 R 243243 CDS YP_882751.1 118462324 4529642 3706619..3707440 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3707440 4529642 MAV_3574 Mycobacterium avium 104 enoyl-CoA hydratase YP_882751.1 3706619 D 243243 CDS YP_882752.1 118463338 4529208 3707604..3708185 1 NC_008595.1 hypothetical protein 3708185 4529208 MAV_3575 Mycobacterium avium 104 hypothetical protein YP_882752.1 3707604 D 243243 CDS YP_882753.1 118463563 4530718 3708187..3709473 1 NC_008595.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; ribonuclease D 3709473 4530718 MAV_3576 Mycobacterium avium 104 ribonuclease D YP_882753.1 3708187 D 243243 CDS YP_882754.1 118464409 4530803 complement(3709513..3711438) 1 NC_008595.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3711438 dxs 4530803 dxs Mycobacterium avium 104 1-deoxy-D-xylulose-5-phosphate synthase YP_882754.1 3709513 R 243243 CDS YP_882755.1 118464939 4528200 3711512..3711955 1 NC_008595.1 identified by match to protein family HMM PF00571; CBS domain-containing protein 3711955 4528200 MAV_3578 Mycobacterium avium 104 CBS domain-containing protein YP_882755.1 3711512 D 243243 CDS YP_882756.1 118465205 4529842 3711972..3713261 1 NC_008595.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; citrate transporter 3713261 4529842 MAV_3579 Mycobacterium avium 104 citrate transporter YP_882756.1 3711972 D 243243 CDS YP_882757.1 118465758 4530451 complement(3713341..3714528) 1 NC_008595.1 cg2084; identified by match to protein family HMM PF01938; match to protein family HMM PF05958; RNA methyltransferase 3714528 4530451 MAV_3580 Mycobacterium avium 104 RNA methyltransferase YP_882757.1 3713341 R 243243 CDS YP_882758.1 118466136 4527902 complement(3714549..3716543) 1 NC_008595.1 amino acid permease 3716543 4527902 MAV_3581 Mycobacterium avium 104 amino acid permease YP_882758.1 3714549 R 243243 CDS YP_882759.1 118465222 4529859 3716680..3717336 1 NC_008595.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; TrkA protein 3717336 4529859 MAV_3582 Mycobacterium avium 104 TrkA protein YP_882759.1 3716680 D 243243 CDS YP_882760.1 118465796 4526109 3717492..3718148 1 NC_008595.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; TrkB protein 3718148 4526109 MAV_3583 Mycobacterium avium 104 TrkB protein YP_882760.1 3717492 D 243243 CDS YP_882761.1 118464117 4526288 complement(3718160..3718801) 1 NC_008595.1 hypothetical protein 3718801 4526288 MAV_3584 Mycobacterium avium 104 hypothetical protein YP_882761.1 3718160 R 243243 CDS YP_882762.1 118464725 4529412 complement(3718861..3719211) 1 NC_008595.1 identified by match to protein family HMM PF01336; OB-fold nucleic acid binding domain-containing protein 3719211 4529412 MAV_3585 Mycobacterium avium 104 OB-fold nucleic acid binding domain-containing protein YP_882762.1 3718861 R 243243 CDS YP_882763.1 118464294 4529582 3719342..3720667 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3720667 4529582 MAV_3586 Mycobacterium avium 104 transposase, Mutator family protein YP_882763.1 3719342 D 243243 CDS YP_882764.1 118462484 4530680 3720760..3721458 1 NC_008595.1 hypothetical protein 3721458 4530680 MAV_3587 Mycobacterium avium 104 hypothetical protein YP_882764.1 3720760 D 243243 CDS YP_882765.1 118463014 4526307 complement(3721474..3722250) 1 NC_008595.1 hypothetical protein 3722250 4526307 MAV_3588 Mycobacterium avium 104 hypothetical protein YP_882765.1 3721474 R 243243 CDS YP_882766.1 118466460 4528681 complement(3722331..3722795) 1 NC_008595.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3722795 dut 4528681 dut Mycobacterium avium 104 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_882766.1 3722331 R 243243 CDS YP_882767.1 118467103 4526364 3722869..3723306 1 NC_008595.1 hypothetical protein 3723306 4526364 MAV_3590 Mycobacterium avium 104 hypothetical protein YP_882767.1 3722869 D 243243 CDS YP_882768.1 118465397 4525657 complement(3723311..3723613) 1 NC_008595.1 hypothetical protein 3723613 4525657 MAV_3591 Mycobacterium avium 104 hypothetical protein YP_882768.1 3723311 R 243243 CDS YP_882769.1 118462495 4530691 3723791..3724459 1 NC_008595.1 hypothetical protein 3724459 4530691 MAV_3592 Mycobacterium avium 104 hypothetical protein YP_882769.1 3723791 D 243243 CDS YP_882770.1 118466036 4528044 complement(3724465..3725319) 1 NC_008595.1 identified by match to protein family HMM PF00459; inositol-1-monophosphatase 3725319 4528044 MAV_3593 Mycobacterium avium 104 inositol-1-monophosphatase YP_882770.1 3724465 R 243243 CDS YP_882771.1 118465228 4525599 3725445..3726251 1 NC_008595.1 identified by match to protein family HMM PF00480; polyphosphate glucokinase 3726251 4525599 MAV_3594 Mycobacterium avium 104 polyphosphate glucokinase YP_882771.1 3725445 D 243243 CDS YP_882772.1 118465794 4526107 3726468..3727958 1 NC_008595.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 3727958 4526107 MAV_3595 Mycobacterium avium 104 RNA polymerase sigma factor YP_882772.1 3726468 D 243243 CDS YP_882773.1 118465231 4525602 3728178..3728987 1 NC_008595.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 3728987 fabG 4525602 fabG Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_882773.1 3728178 D 243243 CDS YP_882774.1 118463786 4530137 3729140..3729529 1 NC_008595.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP 3729529 4530137 MAV_3598 Mycobacterium avium 104 endoribonuclease L-PSP YP_882774.1 3729140 D 243243 CDS YP_882775.1 118464336 4529841 complement(3729484..3729834) 1 NC_008595.1 identified by match to protein family HMM PF06108; hypothetical protein 3729834 4529841 MAV_3597 Mycobacterium avium 104 hypothetical protein YP_882775.1 3729484 R 243243 CDS YP_882776.1 118466329 4528760 3730039..3730152 1 NC_008595.1 hypothetical protein 3730152 4528760 MAV_3599 Mycobacterium avium 104 hypothetical protein YP_882776.1 3730039 D 243243 CDS YP_882777.1 118462877 4527105 3730251..3731252 1 NC_008595.1 identified by match to protein family HMM PF03631; hypothetical protein 3731252 4527105 MAV_3600 Mycobacterium avium 104 hypothetical protein YP_882777.1 3730251 D 243243 CDS YP_882778.1 118462331 4525676 complement(3731253..3731492) 1 NC_008595.1 hypothetical protein 3731492 4525676 MAV_3601 Mycobacterium avium 104 hypothetical protein YP_882778.1 3731253 R 243243 CDS YP_882779.1 118464240 4528613 3731591..3732034 1 NC_008595.1 hypothetical protein 3732034 4528613 MAV_3602 Mycobacterium avium 104 hypothetical protein YP_882779.1 3731591 D 243243 CDS YP_882780.1 118463509 4527689 3732185..3733144 1 NC_008595.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase; RNA polymerase sigma factor SigB 3733144 4527689 MAV_3603 Mycobacterium avium 104 RNA polymerase sigma factor SigB YP_882780.1 3732185 D 243243 CDS YP_882781.1 118465346 4526659 3733274..3733963 1 NC_008595.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent repressor IdeR 3733963 4526659 MAV_3604 Mycobacterium avium 104 iron-dependent repressor IdeR YP_882781.1 3733274 D 243243 CDS YP_882782.1 118464645 4528980 complement(3734008..3735069) 1 NC_008595.1 hypothetical protein 3735069 4528980 MAV_3605 Mycobacterium avium 104 hypothetical protein YP_882782.1 3734008 R 243243 CDS YP_882783.1 118465723 4527458 3735183..3736598 1 NC_008595.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 3736598 4527458 MAV_3606 Mycobacterium avium 104 soluble pyridine nucleotide transhydrogenase YP_882783.1 3735183 D 243243 CDS YP_882784.1 118462442 4525615 complement(3736603..3737439) 1 NC_008595.1 hypothetical protein 3737439 4525615 MAV_3607 Mycobacterium avium 104 hypothetical protein YP_882784.1 3736603 R 243243 CDS YP_882785.1 118466834 4526943 3737669..3738643 1 NC_008595.1 identified by match to protein family HMM PF01908; hypothetical protein 3738643 4526943 MAV_3608 Mycobacterium avium 104 hypothetical protein YP_882785.1 3737669 D 243243 CDS YP_882786.1 118464984 4527476 3738699..3739730 1 NC_008595.1 identified by match to protein family HMM PF00561; hydrolase 3739730 4527476 MAV_3609 Mycobacterium avium 104 hydrolase YP_882786.1 3738699 D 243243 CDS YP_882787.1 118464306 4526636 3739769..3740422 1 NC_008595.1 identified by match to protein family HMM PF02567; thymidylate synthase 3740422 4526636 MAV_3610 Mycobacterium avium 104 thymidylate synthase YP_882787.1 3739769 D 243243 CDS YP_882788.1 118463224 4528798 complement(3740444..3740929) 1 NC_008595.1 hypothetical protein 3740929 4528798 MAV_3611 Mycobacterium avium 104 hypothetical protein YP_882788.1 3740444 R 243243 CDS YP_882789.1 118462512 4528590 complement(3740968..3741432) 1 NC_008595.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; NrdR family transcriptional regulator 3741432 nrdR 4528590 nrdR Mycobacterium avium 104 NrdR family transcriptional regulator YP_882789.1 3740968 R 243243 CDS YP_882790.1 118462953 4526321 complement(3741584..3742078) 1 NC_008595.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 3742078 4526321 MAV_3613 Mycobacterium avium 104 LysM domain-containing protein YP_882790.1 3741584 R 243243 CDS YP_882791.1 118463995 4529257 3742391..3743089 1 NC_008595.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 3743089 lexA 4529257 lexA Mycobacterium avium 104 LexA repressor YP_882791.1 3742391 D 243243 CDS YP_882792.1 118464403 4530797 complement(3743096..3745303) 1 NC_008595.1 hypothetical protein 3745303 4530797 MAV_3615 Mycobacterium avium 104 hypothetical protein YP_882792.1 3743096 R 243243 CDS YP_882793.1 118465985 4526127 3745325..3745564 1 NC_008595.1 hypothetical protein 3745564 4526127 MAV_3617 Mycobacterium avium 104 hypothetical protein YP_882793.1 3745325 D 243243 CDS YP_882794.1 118464122 4526293 complement(3745561..3746721) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; long-chain specific acyl-CoA dehydrogenase 3746721 4526293 MAV_3616 Mycobacterium avium 104 long-chain specific acyl-CoA dehydrogenase YP_882794.1 3745561 R 243243 CDS YP_882795.1 118464862 4530698 complement(3746798..3748246) 1 NC_008595.1 identified by match to protein family HMM PF01926; GTPase 3748246 4530698 MAV_3618 Mycobacterium avium 104 GTPase YP_882795.1 3746798 R 243243 CDS YP_882796.1 118465575 4526761 complement(3748272..3749156) 1 NC_008595.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3749156 dapF 4526761 dapF Mycobacterium avium 104 diaminopimelate epimerase YP_882796.1 3748272 R 243243 CDS YP_882797.1 118463158 4527796 complement(3749161..3750084) 1 NC_008595.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 3750084 miaA 4527796 miaA Mycobacterium avium 104 tRNA delta(2)-isopentenylpyrophosphate transferase YP_882797.1 3749161 R 243243 CDS YP_882798.1 118466091 4527720 complement(3750102..3750800) 1 NC_008595.1 hypothetical protein 3750800 4527720 MAV_3621 Mycobacterium avium 104 hypothetical protein YP_882798.1 3750102 R 243243 CDS YP_882799.1 118467052 4526508 complement(3750835..3751821) 1 NC_008595.1 hypothetical protein 3751821 4526508 MAV_3622 Mycobacterium avium 104 hypothetical protein YP_882799.1 3750835 R 243243 CDS YP_882800.1 118466470 4528692 complement(3752064..3753389) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 3753389 4528692 MAV_3623 Mycobacterium avium 104 transposase, Mutator family protein YP_882800.1 3752064 R 243243 CDS YP_882801.1 118465976 4528195 3753715..3754974 1 NC_008595.1 identified by match to protein family HMM PF03993; hypothetical protein 3754974 4528195 MAV_3624 Mycobacterium avium 104 hypothetical protein YP_882801.1 3753715 D 243243 CDS YP_882802.1 118465431 4529980 complement(3754984..3757050) 1 NC_008595.1 identified by match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01574; hypothetical protein 3757050 4529980 MAV_3625 Mycobacterium avium 104 hypothetical protein YP_882802.1 3754984 R 243243 CDS YP_882803.1 118462254 4526940 complement(3757135..3757656) 1 NC_008595.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3757656 recX 4526940 recX Mycobacterium avium 104 recombination regulator RecX YP_882803.1 3757135 R 243243 CDS YP_882804.1 118464179 4526489 complement(3757622..3758674) 1 NC_008595.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3758674 recA 4526489 recA Mycobacterium avium 104 recombinase A YP_882804.1 3757622 R 243243 CDS YP_882805.1 118466471 4528693 3758721..3759509 1 NC_008595.1 hypothetical protein 3759509 4528693 MAV_3628 Mycobacterium avium 104 hypothetical protein YP_882805.1 3758721 D 243243 CDS YP_882806.1 118463080 4527579 complement(3759525..3759719) 1 NC_008595.1 hypothetical protein 3759719 4527579 MAV_3629 Mycobacterium avium 104 hypothetical protein YP_882806.1 3759525 R 243243 CDS YP_882807.1 118462671 4530598 complement(3759746..3760030) 1 NC_008595.1 hypothetical protein 3760030 4530598 MAV_3630 Mycobacterium avium 104 hypothetical protein YP_882807.1 3759746 R 243243 CDS YP_882808.1 118464270 4528225 complement(3760075..3761235) 1 NC_008595.1 hypothetical protein 3761235 4528225 MAV_3631 Mycobacterium avium 104 hypothetical protein YP_882808.1 3760075 R 243243 CDS YP_882809.1 118465944 4527940 3761288..3761719 1 NC_008595.1 identified by match to protein family HMM PF07366; match to protein family HMM PF07858; hypothetical protein 3761719 4527940 MAV_3633 Mycobacterium avium 104 hypothetical protein YP_882809.1 3761288 D 243243 CDS YP_882810.1 118467258 4526093 complement(3761658..3762170) 1 NC_008595.1 hypothetical protein 3762170 4526093 MAV_3632 Mycobacterium avium 104 hypothetical protein YP_882810.1 3761658 R 243243 CDS YP_882811.1 118464379 4528268 complement(3762122..3762931) 1 NC_008595.1 hypothetical protein 3762931 4528268 MAV_3634 Mycobacterium avium 104 hypothetical protein YP_882811.1 3762122 R 243243 CDS YP_882812.1 118464812 4527631 complement(3762935..3763762) 1 NC_008595.1 identified by match to protein family HMM PF04012; 35kd antigen 3763762 4527631 MAV_3635 Mycobacterium avium 104 35kd antigen YP_882812.1 3762935 R 243243 CDS YP_882813.1 118466084 4527352 complement(3763881..3764207) 1 NC_008595.1 identified by match to protein family HMM PF01381; DNA-binding protein 3764207 4527352 MAV_3636 Mycobacterium avium 104 DNA-binding protein YP_882813.1 3763881 R 243243 CDS YP_882814.1 118466810 4529057 complement(3764335..3764907) 1 NC_008595.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3764907 pgsA 4529057 pgsA Mycobacterium avium 104 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_882814.1 3764335 R 243243 CDS YP_882815.1 118462752 4527842 3764991..3765515 1 NC_008595.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 3765515 4527842 MAV_3638 Mycobacterium avium 104 N-acetylglutamate synthase YP_882815.1 3764991 D 243243 CDS YP_882816.1 118463435 4528314 complement(3765604..3767931) 1 NC_008595.1 identified by match to protein family HMM PF01580; FtsK/SpoIIIE family protein 3767931 4528314 MAV_3639 Mycobacterium avium 104 FtsK/SpoIIIE family protein YP_882816.1 3765604 R 243243 CDS YP_882817.1 118466902 4528416 3768295..3768609 1 NC_008595.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase domain-containing protein 3768609 4528416 MAV_3640 Mycobacterium avium 104 antibiotic biosynthesis monooxygenase domain-containing protein YP_882817.1 3768295 D 243243 CDS YP_882818.1 118466377 4529939 3768609..3769439 1 NC_008595.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 3769439 4529939 MAV_3641 Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_882818.1 3768609 D 243243 CDS YP_882819.1 118463204 4527531 3769484..3770317 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 3770317 4527531 MAV_3642 Mycobacterium avium 104 methyltransferase, putative, family protein YP_882819.1 3769484 D 243243 CDS YP_882820.1 118463167 4529868 complement(3770426..3772102) 1 NC_008595.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; hydrolase of the metallo-beta-lactamase 3772102 4529868 MAV_3643 Mycobacterium avium 104 hydrolase of the metallo-beta-lactamase YP_882820.1 3770426 R 243243 CDS YP_882821.1 118464138 4528840 complement(3772122..3773024) 1 NC_008595.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3773024 dapA 4528840 dapA Mycobacterium avium 104 dihydrodipicolinate synthase YP_882821.1 3772122 R 243243 CDS YP_882822.1 118464679 4528374 complement(3773068..3773820) 1 NC_008595.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 3773820 thyX 4528374 thyX Mycobacterium avium 104 FAD-dependent thymidylate synthase YP_882822.1 3773068 R 243243 CDS YP_882823.1 118466069 4530039 3774016..3774318 1 NC_008595.1 hypothetical protein 3774318 4530039 MAV_3646 Mycobacterium avium 104 hypothetical protein YP_882823.1 3774016 D 243243 CDS YP_882824.1 118464810 4527629 3774319..3775026 1 NC_008595.1 hypothetical protein 3775026 4527629 MAV_3647 Mycobacterium avium 104 hypothetical protein YP_882824.1 3774319 D 243243 CDS YP_882825.1 118464689 4527878 3775046..3775441 1 NC_008595.1 hypothetical protein 3775441 4527878 MAV_3648 Mycobacterium avium 104 hypothetical protein YP_882825.1 3775046 D 243243 CDS YP_882826.1 118465522 4528940 complement(3775521..3776528) 1 NC_008595.1 type I restriction-modification enzyme, R subunit 3776528 4528940 MAV_3649 Mycobacterium avium 104 type I restriction-modification enzyme, R subunit YP_882826.1 3775521 R 243243 CDS YP_882827.1 118466474 4527604 complement(3776529..3777263) 1 NC_008595.1 hypothetical protein 3777263 4527604 MAV_3650 Mycobacterium avium 104 hypothetical protein YP_882827.1 3776529 R 243243 CDS YP_882828.1 118466885 4526704 complement(3777333..3777863) 1 NC_008595.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 3777863 folA 4526704 folA Mycobacterium avium 104 dihydrofolate reductase YP_882828.1 3777333 R 243243 CDS YP_882829.1 118465321 4526517 complement(3777875..3778675) 1 NC_008595.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3778675 thyA 4526517 thyA Mycobacterium avium 104 thymidylate synthase YP_882829.1 3777875 R 243243 CDS YP_882830.1 118466423 4530167 3778718..3779458 1 NC_008595.1 identified by match to protein family HMM PF01738; hydrolase 3779458 4530167 MAV_3654 Mycobacterium avium 104 hydrolase YP_882830.1 3778718 D 243243 CDS YP_882831.1 118466043 4528051 complement(3779447..3780676) 1 NC_008595.1 identified by match to protein family HMM PF03033; glycosyltransferase GtfE 3780676 4528051 MAV_3653 Mycobacterium avium 104 glycosyltransferase GtfE YP_882831.1 3779447 R 243243 CDS YP_882832.1 118467002 4529472 complement(3780740..3781519) 1 NC_008595.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 3781519 fabG 4529472 fabG Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_882832.1 3780740 R 243243 CDS YP_882833.1 118464710 4529397 3781639..3781965 1 NC_008595.1 hypothetical protein 3781965 4529397 MAV_3656 Mycobacterium avium 104 hypothetical protein YP_882833.1 3781639 D 243243 CDS YP_882834.1 118463587 4529772 complement(3781978..3785205) 1 NC_008595.1 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF01039; match to protein family HMM PF02785; match to protein family HMM PF02786; carbamoyl-phosphate synthase/carboxyl transferase 3785205 4529772 MAV_3657 Mycobacterium avium 104 carbamoyl-phosphate synthase/carboxyl transferase YP_882834.1 3781978 R 243243 CDS YP_882835.1 118465556 4525805 complement(3785202..3786734) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA dehydrogenase 3786734 4525805 MAV_3658 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882835.1 3785202 R 243243 CDS YP_882836.1 118464211 4526891 3786789..3787622 1 NC_008595.1 hypothetical protein 3787622 4526891 MAV_3659 Mycobacterium avium 104 hypothetical protein YP_882836.1 3786789 D 243243 CDS YP_882837.1 118463738 4528146 complement(3787652..3788119) 1 NC_008595.1 multimeric flavodoxin WrbA 3788119 4528146 MAV_3660 Mycobacterium avium 104 multimeric flavodoxin WrbA YP_882837.1 3787652 R 243243 CDS YP_882838.1 118464804 4527623 complement(3788116..3788571) 1 NC_008595.1 identified by match to protein family HMM PF07719; TPR repeat-containing protein 3788571 4527623 MAV_3661 Mycobacterium avium 104 TPR repeat-containing protein YP_882838.1 3788116 R 243243 CDS YP_882839.2 229220807 4526979 complement(3788597..3789334) 1 NC_008595.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 3789334 dapB 4526979 dapB Mycobacterium avium 104 dihydrodipicolinate reductase YP_882839.2 3788597 R 243243 CDS YP_882840.1 118463671 4525963 complement(3789384..3789944) 1 NC_008595.1 hypothetical protein 3789944 4525963 MAV_3663 Mycobacterium avium 104 hypothetical protein YP_882840.1 3789384 R 243243 CDS YP_882841.1 118465911 4528993 3790113..3791468 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 3791468 4528993 MAV_3664 Mycobacterium avium 104 hypothetical protein YP_882841.1 3790113 D 243243 CDS YP_882842.1 118465155 4529245 complement(3791474..3792556) 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 3792556 dapB 4529245 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_882842.1 3791474 R 243243 CDS YP_882843.1 118464443 4525974 complement(3792561..3793556) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 3793556 4525974 MAV_3666 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_882843.1 3792561 R 243243 CDS YP_882844.1 118465395 4525655 complement(3793549..3793737) 1 NC_008595.1 hypothetical protein 3793737 4525655 MAV_3667 Mycobacterium avium 104 hypothetical protein YP_882844.1 3793549 R 243243 CDS YP_882845.1 118463399 4528026 3793753..3794328 1 NC_008595.1 hypothetical protein 3794328 4528026 MAV_3668 Mycobacterium avium 104 hypothetical protein YP_882845.1 3793753 D 243243 CDS YP_882846.1 118465005 4526271 complement(3794337..3795437) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase 3795437 4526271 MAV_3669 Mycobacterium avium 104 oxidoreductase YP_882846.1 3794337 R 243243 CDS YP_882847.1 118466752 4526353 complement(3795434..3797218) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF00561; short chain dehydrogenase 3797218 4526353 MAV_3670 Mycobacterium avium 104 short chain dehydrogenase YP_882847.1 3795434 R 243243 CDS YP_882848.1 118464313 4526643 complement(3797222..3798130) 1 NC_008595.1 FF domain-containing protein 3798130 4526643 MAV_3671 Mycobacterium avium 104 FF domain-containing protein YP_882848.1 3797222 R 243243 CDS YP_882849.1 118464976 4527468 complement(3798306..3798767) 1 NC_008595.1 hypothetical protein 3798767 4527468 MAV_3672 Mycobacterium avium 104 hypothetical protein YP_882849.1 3798306 R 243243 CDS YP_882850.1 118463561 4530716 3798879..3800000 1 NC_008595.1 identified by match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; alanine dehydrogenase 3800000 ald 4530716 ald Mycobacterium avium 104 alanine dehydrogenase YP_882850.1 3798879 D 243243 CDS YP_882851.1 118462535 4527678 complement(3799997..3800989) 1 NC_008595.1 identified by match to protein family HMM PF03060; dioxygenase 3800989 4527678 MAV_3673 Mycobacterium avium 104 dioxygenase YP_882851.1 3799997 R 243243 CDS YP_882852.1 118462445 4525618 complement(3801104..3802477) 1 NC_008595.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; protease 3802477 4525618 MAV_3675 Mycobacterium avium 104 protease YP_882852.1 3801104 R 243243 CDS YP_882853.1 118466887 4526706 complement(3802464..3804710) 1 NC_008595.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR02696; polynucleotide phosphorylase/polyadenylase 3804710 gpsI 4526706 gpsI Mycobacterium avium 104 polynucleotide phosphorylase/polyadenylase YP_882853.1 3802464 R 243243 CDS YP_882854.1 118466362 4529924 complement(3805147..3805416) 1 NC_008595.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3805416 rpsO 4529924 rpsO Mycobacterium avium 104 30S ribosomal protein S15 YP_882854.1 3805147 R 243243 CDS YP_882855.1 118465455 4526223 complement(3805545..3806468) 1 NC_008595.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 3806468 ribF 4526223 ribF Mycobacterium avium 104 bifunctional riboflavin kinase/FMN adenylyltransferase YP_882855.1 3805545 R 243243 CDS YP_882856.1 118465260 4527281 3806632..3807336 1 NC_008595.1 identified by match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron repressor protein 3807336 4527281 MAV_3679 Mycobacterium avium 104 iron repressor protein YP_882856.1 3806632 D 243243 CDS YP_882857.1 118465800 4526113 complement(3807463..3808719) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 3808719 4526113 MAV_3680 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_882857.1 3807463 R 243243 CDS YP_882858.1 118463813 4526068 complement(3808727..3809917) 1 NC_008595.1 lipid-transfer protein 3809917 4526068 MAV_3681 Mycobacterium avium 104 lipid-transfer protein YP_882858.1 3808727 R 243243 CDS YP_882859.1 118464111 4526282 complement(3810050..3810979) 1 NC_008595.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3810979 truB 4526282 truB Mycobacterium avium 104 tRNA pseudouridine synthase B YP_882859.1 3810050 R 243243 CDS YP_882860.1 118463367 4528945 complement(3810976..3811653) 1 NC_008595.1 identified by match to protein family HMM PF01648; Sfp-type phosphopantetheinyl transferase 3811653 4528945 MAV_3683 Mycobacterium avium 104 Sfp-type phosphopantetheinyl transferase YP_882860.1 3810976 R 243243 CDS YP_882861.1 118466859 4529811 complement(3811650..3812615) 1 NC_008595.1 identified by match to protein family HMM PF00149; metallophosphoesterase 3812615 4529811 MAV_3684 Mycobacterium avium 104 metallophosphoesterase YP_882861.1 3811650 R 243243 CDS YP_882862.1 118466108 4527737 3812745..3813335 1 NC_008595.1 hypothetical protein 3813335 4527737 MAV_3685 Mycobacterium avium 104 hypothetical protein YP_882862.1 3812745 D 243243 CDS YP_882863.1 118462527 4527670 3813339..3815066 1 NC_008595.1 identified by match to protein family HMM PF02129; match to protein family HMM TIGR00976; hydrolase CocE/NonD family protein 3815066 4527670 MAV_3687 Mycobacterium avium 104 hydrolase CocE/NonD family protein YP_882863.1 3813339 D 243243 CDS YP_882864.1 118463065 4527564 complement(3815025..3815585) 1 NC_008595.1 hypothetical protein 3815585 4527564 MAV_3686 Mycobacterium avium 104 hypothetical protein YP_882864.1 3815025 R 243243 CDS YP_882865.1 118465388 4529680 complement(3815582..3815851) 1 NC_008595.1 hypothetical protein 3815851 4529680 MAV_3688 Mycobacterium avium 104 hypothetical protein YP_882865.1 3815582 R 243243 CDS YP_882866.1 118463905 4525836 3815922..3816671 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 3816671 4525836 MAV_3689 Mycobacterium avium 104 enoyl-CoA hydratase YP_882866.1 3815922 D 243243 CDS YP_882867.1 118466542 4527010 3816729..3817295 1 NC_008595.1 hypothetical protein 3817295 4527010 MAV_3690 Mycobacterium avium 104 hypothetical protein YP_882867.1 3816729 D 243243 CDS YP_882868.1 118465808 4525910 complement(3817313..3818266) 1 NC_008595.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH family protein 3818266 4525910 MAV_3691 Mycobacterium avium 104 DHH family protein YP_882868.1 3817313 R 243243 CDS YP_882869.1 118464538 4530408 complement(3818283..3818771) 1 NC_008595.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3818771 rbfA 4530408 rbfA Mycobacterium avium 104 ribosome-binding factor A YP_882869.1 3818283 R 243243 CDS YP_882870.1 118463981 4530339 complement(3818822..3821566) 1 NC_008595.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3821566 infB 4530339 infB Mycobacterium avium 104 translation initiation factor IF-2 YP_882870.1 3818822 R 243243 CDS YP_882871.1 118463354 4529888 complement(3821642..3821896) 1 NC_008595.1 identified by match to protein family HMM PF04296; hypothetical protein 3821896 4529888 MAV_3694 Mycobacterium avium 104 hypothetical protein YP_882871.1 3821642 R 243243 CDS YP_882872.1 118462823 4528637 complement(3822060..3823115) 1 NC_008595.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3823115 nusA 4528637 nusA Mycobacterium avium 104 transcription elongation factor NusA YP_882872.1 3822060 R 243243 CDS YP_882873.1 118464499 4525542 complement(3823112..3823648) 1 NC_008595.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3823648 4525542 MAV_3696 Mycobacterium avium 104 hypothetical protein YP_882873.1 3823112 R 243243 CDS YP_882874.1 118463932 4528112 complement(3823645..3823743) 1 NC_008595.1 hypothetical protein 3823743 4528112 MAV_3697 Mycobacterium avium 104 hypothetical protein YP_882874.1 3823645 R 243243 CDS YP_882875.1 118463351 4529885 3823952..3824404 1 NC_008595.1 hypothetical protein 3824404 4529885 MAV_3698 Mycobacterium avium 104 hypothetical protein YP_882875.1 3823952 D 243243 CDS YP_882876.1 118464435 4525966 3824401..3824847 1 NC_008595.1 hypothetical protein 3824847 4525966 MAV_3699 Mycobacterium avium 104 hypothetical protein YP_882876.1 3824401 D 243243 CDS YP_882877.1 118463800 4525882 complement(3824848..3826596) 1 NC_008595.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3826596 proS 4525882 proS Mycobacterium avium 104 prolyl-tRNA synthetase YP_882877.1 3824848 R 243243 CDS YP_882878.1 118464464 4527057 complement(3826654..3827892) 1 NC_008595.1 hypothetical protein 3827892 4527057 MAV_3701 Mycobacterium avium 104 hypothetical protein YP_882878.1 3826654 R 243243 CDS YP_882879.1 118463672 4525964 complement(3828087..3829703) 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 3829703 4525964 MAV_3702 Mycobacterium avium 104 transporter, major facilitator family protein YP_882879.1 3828087 R 243243 CDS YP_882880.1 118462961 4526329 complement(3829737..3830942) 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; uroporphyrin-III C-methyltransferase 3830942 cobA 4526329 cobA Mycobacterium avium 104 uroporphyrin-III C-methyltransferase YP_882880.1 3829737 R 243243 CDS YP_882881.1 118462227 4525564 complement(3830952..3832364) 1 NC_008595.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 3832364 cobB 4525564 cobB Mycobacterium avium 104 cobyrinic acid a,c-diamide synthase YP_882881.1 3830952 R 243243 CDS YP_882882.1 118465406 4525666 complement(3832358..3832972) 1 NC_008595.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 3832972 cobO 4525666 cobO Mycobacterium avium 104 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_882882.1 3832358 R 243243 CDS YP_882883.1 118467114 4526140 complement(3833002..3834843) 1 NC_008595.1 identified by match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM PF07728; chelatase 3834843 4526140 MAV_3706 Mycobacterium avium 104 chelatase YP_882883.1 3833002 R 243243 CDS YP_882884.1 118463837 4526056 complement(3834840..3835310) 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 3835310 4526056 MAV_3707 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_882884.1 3834840 R 243243 CDS YP_882885.2 161579548 4530447 complement(3835413..3836918) 1 NC_008595.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 3836918 mqo 4530447 mqo Mycobacterium avium 104 malate:quinone oxidoreductase YP_882885.2 3835413 R 243243 CDS YP_882886.1 118466304 4528346 3837056..3838066 1 NC_008595.1 hypothetical protein 3838066 4528346 MAV_3709 Mycobacterium avium 104 hypothetical protein YP_882886.1 3837056 D 243243 CDS YP_882887.1 118463129 4529654 3838077..3839456 1 NC_008595.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; mycothione reductase 3839456 4529654 MAV_3710 Mycobacterium avium 104 mycothione reductase YP_882887.1 3838077 D 243243 CDS YP_882888.1 118467039 4526495 3839564..3840709 1 NC_008595.1 identified by match to protein family HMM PF03824; match to protein family HMM TIGR00802; transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family protein 3840709 4526495 MAV_3711 Mycobacterium avium 104 transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family protein YP_882888.1 3839564 D 243243 CDS YP_882889.1 118466463 4528685 3840788..3841921 1 NC_008595.1 identified by match to protein family HMM PF01663; type I phosphodiesterase / nucleotide pyrophosphatase 3841921 4528685 MAV_3712 Mycobacterium avium 104 type I phosphodiesterase / nucleotide pyrophosphatase YP_882889.1 3840788 D 243243 CDS YP_882890.1 118465271 4527292 3841935..3842495 1 NC_008595.1 hypothetical protein 3842495 4527292 MAV_3713 Mycobacterium avium 104 hypothetical protein YP_882890.1 3841935 D 243243 CDS YP_882891.1 118463971 4527218 3842616..3843545 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 3843545 4527218 MAV_3715 Mycobacterium avium 104 PPE family protein YP_882891.1 3842616 D 243243 CDS YP_882892.1 118463373 4528951 complement(3843542..3844318) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 3844318 4528951 MAV_3714 Mycobacterium avium 104 short chain dehydrogenase YP_882892.1 3843542 R 243243 CDS YP_882893.1 118466742 4526343 complement(3845678..3846388) 1 NC_008595.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; class I glutamine amidotransferase, putative 3846388 4526343 MAV_3717 Mycobacterium avium 104 class I glutamine amidotransferase, putative YP_882893.1 3845678 R 243243 CDS YP_882894.1 118466291 4529537 complement(3846423..3847829) 1 NC_008595.1 identified by match to protein family HMM PF00120; glutamine synthetase catalytic domain 3847829 glnA 4529537 glnA Mycobacterium avium 104 glutamine synthetase catalytic domain YP_882894.1 3846423 R 243243 CDS YP_882895.1 118465557 4525806 complement(3847842..3848402) 1 NC_008595.1 hypothetical protein 3848402 4525806 MAV_3719 Mycobacterium avium 104 hypothetical protein YP_882895.1 3847842 R 243243 CDS YP_882896.1 118463744 4528152 complement(3848523..3850016) 1 NC_008595.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 3850016 cobQ 4528152 cobQ Mycobacterium avium 104 cobyric acid synthase YP_882896.1 3848523 R 243243 CDS YP_882897.1 118464198 4529309 complement(3850021..3850878) 1 NC_008595.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 3850878 map 4529309 map Mycobacterium avium 104 methionine aminopeptidase YP_882897.1 3850021 R 243243 CDS YP_882898.1 118465847 4530640 complement(3851543..3853342) 1 NC_008595.1 identified by match to protein family HMM PF00905; match to protein family HMM PF05223; hypothetical protein 3853342 4530640 MAV_3723 Mycobacterium avium 104 hypothetical protein YP_882898.1 3851543 R 243243 CDS YP_882899.1 118464059 4529499 complement(3853519..3854331) 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase 3854331 4529499 MAV_3724 Mycobacterium avium 104 acetyltransferase YP_882899.1 3853519 R 243243 CDS YP_882900.1 118463746 4528154 complement(3854422..3855516) 1 NC_008595.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3855516 ispG 4528154 ispG Mycobacterium avium 104 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_882900.1 3854422 R 243243 CDS YP_882901.1 118462609 4528513 complement(3855621..3856844) 1 NC_008595.1 identified by match to protein family HMM PF02163; peptidase M50 3856844 4528513 MAV_3726 Mycobacterium avium 104 peptidase M50 YP_882901.1 3855621 R 243243 CDS YP_882902.1 118466156 4528778 complement(3856864..3858087) 1 NC_008595.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3858087 dxr 4528778 dxr Mycobacterium avium 104 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_882902.1 3856864 R 243243 CDS YP_882903.1 118466671 4526621 complement(3858092..3859321) 1 NC_008595.1 identified by match to protein family HMM PF02683; cytochrome C biogenesis protein transmembrane region 3859321 4526621 MAV_3728 Mycobacterium avium 104 cytochrome C biogenesis protein transmembrane region YP_882903.1 3858092 R 243243 CDS YP_882904.1 118465076 4525893 complement(3859323..3859796) 1 NC_008595.1 15 kDa antigen 3859796 4525893 MAV_3729 Mycobacterium avium 104 15 kDa antigen YP_882904.1 3859323 R 243243 CDS YP_882905.1 118466343 4530483 complement(3861008..3861943) 1 NC_008595.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 3861943 cdsA 4530483 cdsA Mycobacterium avium 104 phosphatidate cytidylyltransferase YP_882905.1 3861008 R 243243 CDS YP_882906.1 118463206 4527533 complement(3861976..3862533) 1 NC_008595.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 3862533 frr 4527533 frr Mycobacterium avium 104 ribosome recycling factor YP_882906.1 3861976 R 243243 CDS YP_882907.1 118462289 4529294 complement(3862655..3863344) 1 NC_008595.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR02075; uridylate kinase 3863344 pyrH 4529294 pyrH Mycobacterium avium 104 uridylate kinase YP_882907.1 3862655 R 243243 CDS YP_882908.1 118462682 4530610 3863784..3864023 1 NC_008595.1 identified by match to protein family HMM PF05532; hypothetical protein 3864023 4530610 MAV_3734 Mycobacterium avium 104 hypothetical protein YP_882908.1 3863784 D 243243 CDS YP_882909.1 118465229 4525600 3864192..3864887 1 NC_008595.1 identified by match to protein family HMM PF00486; GlnR family transcriptional regulator 3864887 4525600 MAV_3735 Mycobacterium avium 104 GlnR family transcriptional regulator YP_882909.1 3864192 D 243243 CDS YP_882910.1 118467196 4528430 complement(3864911..3865879) 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase domain-containing protein 3865879 4528430 MAV_3736 Mycobacterium avium 104 acyltransferase domain-containing protein YP_882910.1 3864911 R 243243 CDS YP_882911.1 118464095 4525856 complement(3865946..3866518) 1 NC_008595.1 hypothetical protein 3866518 4525856 MAV_3737 Mycobacterium avium 104 hypothetical protein YP_882911.1 3865946 R 243243 CDS YP_882912.1 118464828 4529731 3866832..3867008 1 NC_008595.1 hypothetical protein 3867008 4529731 MAV_3738 Mycobacterium avium 104 hypothetical protein YP_882912.1 3866832 D 243243 CDS YP_882913.1 118466983 4529510 complement(3867998..3868411) 1 NC_008595.1 identified by match to protein family HMM PF06150; ChaB family protein 3868411 4529510 MAV_3740 Mycobacterium avium 104 ChaB family protein YP_882913.1 3867998 R 243243 CDS YP_882914.1 118463730 4528138 3868425..3868952 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3868952 4528138 MAV_3741 Mycobacterium avium 104 MarR family transcriptional regulator YP_882914.1 3868425 D 243243 CDS YP_882915.1 118465212 4529849 complement(3870433..3871260) 1 NC_008595.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 3871260 tsf 4529849 tsf Mycobacterium avium 104 elongation factor Ts YP_882915.1 3870433 R 243243 CDS YP_882916.1 118464674 4528369 complement(3871274..3872104) 1 NC_008595.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 3872104 rpsB 4528369 rpsB Mycobacterium avium 104 30S ribosomal protein S2 YP_882916.1 3871274 R 243243 CDS YP_882917.1 118463588 4529773 3872379..3872882 1 NC_008595.1 identified by match to protein family HMM PF01551; M23 peptidase domain-containing protein 3872882 4529773 MAV_3745 Mycobacterium avium 104 M23 peptidase domain-containing protein YP_882917.1 3872379 D 243243 CDS YP_882918.1 118462850 4526032 complement(3872983..3873888) 1 NC_008595.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 3873888 xerC 4526032 xerC Mycobacterium avium 104 site-specific tyrosine recombinase XerC YP_882918.1 3872983 R 243243 CDS YP_882919.1 118464771 4529126 complement(3873922..3875082) 1 NC_008595.1 identified by match to protein family HMM PF01070; lactate 2-monooxygenase 3875082 4529126 MAV_3747 Mycobacterium avium 104 lactate 2-monooxygenase YP_882919.1 3873922 R 243243 CDS YP_882920.1 118466334 4528765 complement(3875108..3875959) 1 NC_008595.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore utilization protein 3875959 4528765 MAV_3748 Mycobacterium avium 104 siderophore utilization protein YP_882920.1 3875108 R 243243 CDS YP_882921.1 118463022 4526315 complement(3876003..3877169) 1 NC_008595.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; smf family protein 3877169 4526315 MAV_3749 Mycobacterium avium 104 smf family protein YP_882921.1 3876003 R 243243 CDS YP_882922.1 118462489 4530685 3877280..3877555 1 NC_008595.1 hypothetical protein 3877555 4530685 MAV_3750 Mycobacterium avium 104 hypothetical protein YP_882922.1 3877280 D 243243 CDS YP_882923.1 118464223 4528596 complement(3877582..3879093) 1 NC_008595.1 identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368; Mg-chelatase subunits D/I family protein, ComM subfamily protein 3879093 4528596 MAV_3751 Mycobacterium avium 104 Mg-chelatase subunits D/I family protein, ComM subfamily protein YP_882923.1 3877582 R 243243 CDS YP_882924.1 118463594 4529780 complement(3879093..3879479) 1 NC_008595.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 3879479 4529780 MAV_3752 Mycobacterium avium 104 hypothetical protein YP_882924.1 3879093 R 243243 CDS YP_882925.1 118462343 4525688 complement(3879593..3880411) 1 NC_008595.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 3880411 fdhD 4525688 fdhD Mycobacterium avium 104 formate dehydrogenase accessory protein YP_882925.1 3879593 R 243243 CDS YP_882926.1 118464369 4530512 complement(3880468..3881451) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase 3881451 4530512 MAV_3754 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_882926.1 3880468 R 243243 CDS YP_882927.1 118467325 4526963 3881746..3882516 1 NC_008595.1 identified by match to protein family HMM PF03861; ANTAR domain-containing protein 3882516 4526963 MAV_3755 Mycobacterium avium 104 ANTAR domain-containing protein YP_882927.1 3881746 D 243243 CDS YP_882928.1 118462895 4527503 complement(3882523..3882828) 1 NC_008595.1 hypothetical protein 3882828 4527503 MAV_3756 Mycobacterium avium 104 hypothetical protein YP_882928.1 3882523 R 243243 CDS YP_882929.1 118466028 4529914 complement(3882891..3883583) 1 NC_008595.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 3883583 rnhB 4529914 rnhB Mycobacterium avium 104 ribonuclease HII YP_882929.1 3882891 R 243243 CDS YP_882930.1 118465284 4529320 complement(3883613..3884512) 1 NC_008595.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 3884512 lepB 4529320 lepB Mycobacterium avium 104 signal peptidase I YP_882930.1 3883613 R 243243 CDS YP_882931.1 118465599 4527858 complement(3884570..3884911) 1 NC_008595.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3884911 rplS 4527858 rplS Mycobacterium avium 104 50S ribosomal protein L19 YP_882931.1 3884570 R 243243 CDS YP_882932.1 118464874 4530710 3885256..3886224 1 NC_008595.1 LppW protein 3886224 4530710 MAV_3761 Mycobacterium avium 104 LppW protein YP_882932.1 3885256 D 243243 CDS YP_882933.1 118464490 4528864 complement(3886221..3886940) 1 NC_008595.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3886940 trmD 4528864 trmD Mycobacterium avium 104 tRNA (guanine-N(1)-)-methyltransferase YP_882933.1 3886221 R 243243 CDS YP_882934.1 118463723 4528073 complement(3886947..3887474) 1 NC_008595.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3887474 rimM 4528073 rimM Mycobacterium avium 104 16S rRNA-processing protein RimM YP_882934.1 3886947 R 243243 CDS YP_882935.1 118462639 4529379 complement(3887484..3887726) 1 NC_008595.1 hypothetical protein 3887726 4529379 MAV_3763 Mycobacterium avium 104 hypothetical protein YP_882935.1 3887484 R 243243 CDS YP_882936.1 118463389 4528016 complement(3887735..3888247) 1 NC_008595.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3888247 rpsP 4528016 rpsP Mycobacterium avium 104 30S ribosomal protein S16 YP_882936.1 3887735 R 243243 CDS YP_882937.1 118465763 4530456 complement(3888380..3888799) 1 NC_008595.1 hypothetical protein 3888799 4530456 MAV_3765 Mycobacterium avium 104 hypothetical protein YP_882937.1 3888380 R 243243 CDS YP_882938.1 118465675 4525733 3888832..3889728 1 NC_008595.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 3889728 4525733 MAV_3766 Mycobacterium avium 104 D-alanyl-D-alanine carboxypeptidase YP_882938.1 3888832 D 243243 CDS YP_882939.1 118466229 4526575 complement(3889832..3890425) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3890425 4526575 MAV_3767 Mycobacterium avium 104 TetR family transcriptional regulator YP_882939.1 3889832 R 243243 CDS YP_882940.1 118466776 4529334 complement(3890427..3892232) 1 NC_008595.1 N-acyl-D-glutamate amidohydrolase 3892232 4529334 MAV_3768 Mycobacterium avium 104 N-acyl-D-glutamate amidohydrolase YP_882940.1 3890427 R 243243 CDS YP_882941.1 118462905 4528168 complement(3892352..3893443) 1 NC_008595.1 identified by match to protein family HMM PF01979; amidohydrolase 3893443 4528168 MAV_3769 Mycobacterium avium 104 amidohydrolase YP_882941.1 3892352 R 243243 CDS YP_882942.1 118466702 4529709 complement(3893449..3895002) 1 NC_008595.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 3895002 ffh 4529709 ffh Mycobacterium avium 104 signal recognition particle protein YP_882942.1 3893449 R 243243 CDS YP_882943.1 118464714 4529401 3895218..3896009 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 3896009 4529401 MAV_3771 Mycobacterium avium 104 alpha/beta hydrolase YP_882943.1 3895218 D 243243 CDS YP_882944.1 118462616 4526418 3896111..3897850 1 NC_008595.1 identified by match to protein family HMM PF04851; DNA or RNA helicase of superfamily protein II 3897850 4526418 MAV_3772 Mycobacterium avium 104 DNA or RNA helicase of superfamily protein II YP_882944.1 3896111 D 243243 CDS YP_882945.1 118464551 4530421 complement(3897867..3900311) 1 NC_008595.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK; PII uridylyl-transferase 3900311 glnD 4530421 glnD Mycobacterium avium 104 PII uridylyl-transferase YP_882945.1 3897867 R 243243 CDS YP_882946.1 118462409 4525719 complement(3900357..3900695) 1 NC_008595.1 identified by match to protein family HMM PF00543; nitrogen regulatory protein P-II 3900695 4525719 MAV_3774 Mycobacterium avium 104 nitrogen regulatory protein P-II YP_882946.1 3900357 R 243243 CDS YP_882947.1 118465181 4528671 complement(3900692..3902125) 1 NC_008595.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 3902125 amt 4528671 amt Mycobacterium avium 104 ammonium transporter YP_882947.1 3900692 R 243243 CDS YP_882948.1 118465902 4528984 complement(3902271..3903557) 1 NC_008595.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 3903557 ftsY 4528984 ftsY Mycobacterium avium 104 signal recognition particle-docking protein FtsY YP_882948.1 3902271 R 243243 CDS YP_882949.1 118466622 4526860 complement(3903627..3907217) 1 NC_008595.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168; chromosome segregation protein SMC 3907217 smc 4526860 smc Mycobacterium avium 104 chromosome segregation protein SMC YP_882949.1 3903627 R 243243 CDS YP_882950.1 118466100 4527729 3907266..3907385 1 NC_008595.1 hypothetical protein 3907385 4527729 MAV_3778 Mycobacterium avium 104 hypothetical protein YP_882950.1 3907266 D 243243 CDS YP_882951.1 118467285 4527243 complement(3907417..3907710) 1 NC_008595.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 3907710 4527243 MAV_3779 Mycobacterium avium 104 acylphosphatase YP_882951.1 3907417 R 243243 CDS YP_882952.1 118466612 4526849 complement(3907697..3908053) 1 NC_008595.1 identified by match to protein family HMM PF02566; hypothetical protein 3908053 4526849 MAV_3780 Mycobacterium avium 104 hypothetical protein YP_882952.1 3907697 R 243243 CDS YP_882953.1 118466070 4530040 3908175..3908951 1 NC_008595.1 identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase 3908951 4530040 MAV_3781 Mycobacterium avium 104 GlcNAc-PI de-N-acetylase YP_882953.1 3908175 D 243243 CDS YP_882954.1 118464268 4528223 complement(3908958..3909809) 1 NC_008595.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 3909809 mutM 4528223 mutM Mycobacterium avium 104 formamidopyrimidine-DNA glycosylase YP_882954.1 3908958 R 243243 CDS YP_882955.1 118462414 4525724 complement(3909830..3910543) 1 NC_008595.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 3910543 rnc 4525724 rnc Mycobacterium avium 104 ribonuclease III YP_882955.1 3909830 R 243243 CDS YP_882956.1 118463507 4527687 complement(3910540..3911073) 1 NC_008595.1 identified by match to protein family HMM PF02620; hypothetical protein 3911073 4527687 MAV_3784 Mycobacterium avium 104 hypothetical protein YP_882956.1 3910540 R 243243 CDS YP_882957.1 118462739 4527810 complement(3911196..3911933) 1 NC_008595.1 hypothetical protein 3911933 4527810 MAV_3785 Mycobacterium avium 104 hypothetical protein YP_882957.1 3911196 R 243243 CDS YP_882958.1 118465783 4526918 complement(3912086..3913066) 1 NC_008595.1 hypothetical protein 3913066 4526918 MAV_3786 Mycobacterium avium 104 hypothetical protein YP_882958.1 3912086 R 243243 CDS YP_882959.1 118465237 4525608 3913258..3914421 1 NC_008595.1 identified by match to protein family HMM PF03773; hypothetical protein 3914421 4525608 MAV_3787 Mycobacterium avium 104 hypothetical protein YP_882959.1 3913258 D 243243 CDS YP_882960.1 118464378 4528267 complement(3914463..3916172) 1 NC_008595.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 3916172 4528267 MAV_3788 Mycobacterium avium 104 acetolactate synthase catalytic subunit YP_882960.1 3914463 R 243243 CDS YP_882961.1 118463763 4528007 3916471..3917487 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 3917487 4528007 MAV_3789 Mycobacterium avium 104 hypothetical protein YP_882961.1 3916471 D 243243 CDS YP_882962.1 118462904 4528167 3917497..3918936 1 NC_008595.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; integrase/recombinase 3918936 4528167 MAV_3790 Mycobacterium avium 104 integrase/recombinase YP_882962.1 3917497 D 243243 CDS YP_882963.1 118464711 4529398 3919180..3920178 1 NC_008595.1 identified by match to protein family HMM PF00004; ATPase 3920178 4529398 MAV_3791 Mycobacterium avium 104 ATPase YP_882963.1 3919180 D 243243 CDS YP_882964.1 118466403 4526246 3920209..3922743 1 NC_008595.1 Y4bN protein 3922743 4526246 MAV_3792 Mycobacterium avium 104 Y4bN protein YP_882964.1 3920209 D 243243 CDS YP_882965.1 118465708 4530330 complement(3923136..3923282) 1 NC_008595.1 hypothetical protein 3923282 4530330 MAV_3793 Mycobacterium avium 104 hypothetical protein YP_882965.1 3923136 R 243243 CDS YP_882966.1 118463233 4528807 complement(3923290..3924789) 1 NC_008595.1 replication initiation protein 3924789 4528807 MAV_3794 Mycobacterium avium 104 replication initiation protein YP_882966.1 3923290 R 243243 CDS YP_882967.1 118465255 4528473 complement(3924782..3926224) 1 NC_008595.1 identified by match to protein family HMM PF01580; cell divisionftsk/SpoIIIE 3926224 4528473 MAV_3795 Mycobacterium avium 104 cell divisionftsk/SpoIIIE YP_882967.1 3924782 R 243243 CDS YP_882968.1 118466321 4528752 complement(3926324..3926662) 1 NC_008595.1 Pra protein 3926662 4528752 MAV_3796 Mycobacterium avium 104 Pra protein YP_882968.1 3926324 R 243243 CDS YP_882969.1 118466687 4530429 3926922..3927719 1 NC_008595.1 identified by match to protein family HMM PF01381; XRE family transcriptional regulator 3927719 4530429 MAV_3797 Mycobacterium avium 104 XRE family transcriptional regulator YP_882969.1 3926922 D 243243 CDS YP_882970.1 118467094 4526394 3927727..3928194 1 NC_008595.1 identified by match to protein family HMM PF00293; nudix hydrolase 3928194 4526394 MAV_3798 Mycobacterium avium 104 nudix hydrolase YP_882970.1 3927727 D 243243 CDS YP_882971.1 118462220 4525556 complement(3928208..3928666) 1 NC_008595.1 metal dependent phosphohydrolase 3928666 4525556 MAV_3799 Mycobacterium avium 104 metal dependent phosphohydrolase YP_882971.1 3928208 R 243243 CDS YP_882972.1 118462932 4530216 complement(3929077..3929349) 1 NC_008595.1 HTH-type transcriptional regulator 3929349 4530216 MAV_3800 Mycobacterium avium 104 HTH-type transcriptional regulator YP_882972.1 3929077 R 243243 CDS YP_882973.1 118465896 4527930 complement(3933023..3933448) 1 NC_008595.1 hypothetical protein 3933448 4527930 MAV_3802 Mycobacterium avium 104 hypothetical protein YP_882973.1 3933023 R 243243 CDS YP_882974.1 118466924 4527759 complement(3933523..3934146) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3934146 4527759 MAV_3803 Mycobacterium avium 104 TetR family transcriptional regulator YP_882974.1 3933523 R 243243 CDS YP_882975.1 118463640 4528542 complement(3934143..3934658) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 3934658 4528542 MAV_3804 Mycobacterium avium 104 thioesterase YP_882975.1 3934143 R 243243 CDS YP_882976.1 118464724 4529411 3934801..3935469 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 3935469 4529411 MAV_3805 Mycobacterium avium 104 transcriptional regulator YP_882976.1 3934801 D 243243 CDS YP_882977.1 118465598 4527857 complement(3935650..3936276) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF08028; dibenzothiophene desulfurization enzyme C 3936276 4527857 MAV_3806 Mycobacterium avium 104 dibenzothiophene desulfurization enzyme C YP_882977.1 3935650 R 243243 CDS YP_882978.1 118462809 4529029 3936431..3936550 1 NC_008595.1 hypothetical protein 3936550 4529029 MAV_3807 Mycobacterium avium 104 hypothetical protein YP_882978.1 3936431 D 243243 CDS YP_882979.1 118466378 4529940 complement(3936894..3937847) 1 NC_008595.1 2'-hydroxybiphenyl-2-sulfinate desulfinase 3937847 4529940 MAV_3808 Mycobacterium avium 104 2'-hydroxybiphenyl-2-sulfinate desulfinase YP_882979.1 3936894 R 243243 CDS YP_882980.1 118462422 4528285 complement(3937964..3939322) 1 NC_008595.1 identified by match to protein family HMM PF00296; dibenzothiophene desulfurization enzyme A 3939322 4528285 MAV_3809 Mycobacterium avium 104 dibenzothiophene desulfurization enzyme A YP_882980.1 3937964 R 243243 CDS YP_882981.1 118463446 4529688 complement(3939813..3940295) 1 NC_008595.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3940295 coaD 4529688 coaD Mycobacterium avium 104 phosphopantetheine adenylyltransferase YP_882981.1 3939813 R 243243 CDS YP_882982.1 118463857 4529956 complement(3940417..3940971) 1 NC_008595.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; methyltransferase 3940971 4529956 MAV_3811 Mycobacterium avium 104 methyltransferase YP_882982.1 3940417 R 243243 CDS YP_882983.1 118464317 4526648 complement(3940982..3941617) 1 NC_008595.1 identified by match to protein family HMM PF07884; integral membrane protein 3941617 4526648 MAV_3812 Mycobacterium avium 104 integral membrane protein YP_882983.1 3940982 R 243243 CDS YP_882984.1 118465290 4529326 complement(3941614..3942381) 1 NC_008595.1 hypothetical protein 3942381 4529326 MAV_3813 Mycobacterium avium 104 hypothetical protein YP_882984.1 3941614 R 243243 CDS YP_882985.1 118463913 4525844 complement(3942477..3943598) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 3943598 4525844 MAV_3814 Mycobacterium avium 104 alpha/beta hydrolase YP_882985.1 3942477 R 243243 CDS YP_882986.1 118467238 4529795 3943777..3943929 1 NC_008595.1 morphine 6-dehydrogenase 3943929 4529795 MAV_3815 Mycobacterium avium 104 morphine 6-dehydrogenase YP_882986.1 3943777 D 243243 CDS YP_882987.1 118463340 4529210 3943988..3944776 1 NC_008595.1 identified by match to protein family HMM PF00248; 2,5-diketo-D-gluconic acid reductase A 3944776 4529210 MAV_3816 Mycobacterium avium 104 2,5-diketo-D-gluconic acid reductase A YP_882987.1 3943988 D 243243 CDS YP_882988.1 118463371 4528949 complement(3944780..3945496) 1 NC_008595.1 hypothetical protein 3945496 4528949 MAV_3817 Mycobacterium avium 104 hypothetical protein YP_882988.1 3944780 R 243243 CDS YP_882989.1 118462797 4525766 complement(3945493..3947709) 1 NC_008595.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3947709 recG 4525766 recG Mycobacterium avium 104 ATP-dependent DNA helicase RecG YP_882989.1 3945493 R 243243 CDS YP_882990.1 118466231 4526577 complement(3947712..3949439) 1 NC_008595.1 identified by match to protein family HMM PF02734; DAK2 domain-containing protein 3949439 4526577 MAV_3819 Mycobacterium avium 104 DAK2 domain-containing protein YP_882990.1 3947712 R 243243 CDS YP_882991.1 118465106 4529997 3949998..3950537 1 NC_008595.1 hypothetical protein 3950537 4529997 MAV_3821 Mycobacterium avium 104 hypothetical protein YP_882991.1 3949998 D 243243 CDS YP_882992.1 118464463 4527056 3950666..3950860 1 NC_008595.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3950860 rpmB 4527056 rpmB Mycobacterium avium 104 50S ribosomal protein L28 YP_882992.1 3950666 D 243243 CDS YP_882993.1 118463873 4527751 complement(3950874..3951695) 1 NC_008595.1 identified by match to protein family HMM PF00106; carveol dehydrogenase 3951695 4527751 MAV_3823 Mycobacterium avium 104 carveol dehydrogenase YP_882993.1 3950874 R 243243 CDS YP_882994.1 118463309 4529549 complement(3951707..3952597) 1 NC_008595.1 identified by match to protein family HMM PF00106; dehydrogenase 3952597 4529549 MAV_3824 Mycobacterium avium 104 dehydrogenase YP_882994.1 3951707 R 243243 CDS YP_882995.1 118462793 4525761 3952682..3953125 1 NC_008595.1 hypothetical protein 3953125 4525761 MAV_3825 Mycobacterium avium 104 hypothetical protein YP_882995.1 3952682 D 243243 CDS YP_882996.1 118465768 4526903 3954495..3955325 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 3955325 4526903 MAV_3827 Mycobacterium avium 104 short chain dehydrogenase YP_882996.1 3954495 D 243243 CDS YP_882997.1 118465585 4527132 complement(3955454..3956137) 1 NC_008595.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3956137 ung 4527132 ung Mycobacterium avium 104 uracil-DNA glycosylase YP_882997.1 3955454 R 243243 CDS YP_882998.1 118465074 4525891 complement(3956190..3957137) 1 NC_008595.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 3957137 thiL 4525891 thiL Mycobacterium avium 104 thiamine monophosphate kinase YP_882998.1 3956190 R 243243 CDS YP_882999.1 118463882 4530559 3957231..3957794 1 NC_008595.1 hypothetical protein 3957794 4530559 MAV_3831 Mycobacterium avium 104 hypothetical protein YP_882999.1 3957231 D 243243 CDS YP_883000.1 118464178 4526488 complement(3957791..3958900) 1 NC_008595.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 3958900 ddl 4526488 ddl Mycobacterium avium 104 D-alanyl-alanine synthetase A YP_883000.1 3957791 R 243243 CDS YP_883001.1 118466421 4530165 3960865..3963057 1 NC_008595.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3963057 ppk 4530165 ppk Mycobacterium avium 104 polyphosphate kinase YP_883001.1 3960865 D 243243 CDS YP_883002.1 118466204 4530194 3963142..3964089 1 NC_008595.1 identified by match to protein family HMM PF00293; match to protein family HMM PF00300; hydrolase, NUDIX family protein 3964089 4530194 MAV_3835 Mycobacterium avium 104 hydrolase, NUDIX family protein YP_883002.1 3963142 D 243243 CDS YP_883003.1 118465605 4527864 complement(3964184..3964837) 1 NC_008595.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 3964837 hup 4527864 hup Mycobacterium avium 104 DNA-binding protein HU YP_883003.1 3964184 R 243243 CDS YP_883004.1 118465097 4529988 complement(3965034..3965630) 1 NC_008595.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 3965630 leuD 4529988 leuD Mycobacterium avium 104 isopropylmalate isomerase small subunit YP_883004.1 3965034 R 243243 CDS YP_883005.1 118463029 4528870 complement(3965656..3967086) 1 NC_008595.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 3967086 leuC 4528870 leuC Mycobacterium avium 104 isopropylmalate isomerase large subunit YP_883005.1 3965656 R 243243 CDS YP_883006.1 118462472 4528726 3967212..3967874 1 NC_008595.1 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 3967874 4528726 MAV_3839 Mycobacterium avium 104 IclR family transcriptional regulator YP_883006.1 3967212 D 243243 CDS YP_883007.1 118466402 4526245 3967978..3968490 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 3968490 4526245 MAV_3840 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_883007.1 3967978 D 243243 CDS YP_883008.1 118465306 4526560 complement(3970363..3971169) 1 NC_008595.1 identified by match to protein family HMM PF01557; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 3971169 4526560 MAV_3844 Mycobacterium avium 104 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_883008.1 3970363 R 243243 CDS YP_883009.1 118465421 4529970 3971269..3972660 1 NC_008595.1 identified by match to protein family HMM PF07690; sugar transporter family protein 3972660 4529970 MAV_3846 Mycobacterium avium 104 sugar transporter family protein YP_883009.1 3971269 D 243243 CDS YP_883010.1 118463554 4526821 complement(3972560..3973570) 1 NC_008595.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 3973570 leuB 4526821 leuB Mycobacterium avium 104 3-isopropylmalate dehydrogenase YP_883010.1 3972560 R 243243 CDS YP_883011.1 118463523 4526828 complement(3973620..3975206) 1 NC_008595.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3975206 serA 4526828 serA Mycobacterium avium 104 D-3-phosphoglycerate dehydrogenase YP_883011.1 3973620 R 243243 CDS YP_883012.1 118462933 4530217 3975236..3976663 1 NC_008595.1 P49 protein 3976663 4530217 MAV_3848 Mycobacterium avium 104 P49 protein YP_883012.1 3975236 D 243243 CDS YP_883013.1 118467091 4526391 3976660..3977259 1 NC_008595.1 identified by match to protein family HMM PF00258; match to protein family HMM PF03358; match to protein family HMM TIGR01755; NAD(P)H:quinone oxidoreductase, type IV 3977259 wrbA 4526391 wrbA Mycobacterium avium 104 NAD(P)H:quinone oxidoreductase, type IV YP_883013.1 3976660 D 243243 CDS YP_883014.1 118466513 4527186 complement(3977329..3978330) 1 NC_008595.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 3978330 ilvC 4527186 ilvC Mycobacterium avium 104 ketol-acid reductoisomerase YP_883014.1 3977329 R 243243 CDS YP_883015.1 118465974 4528193 complement(3978393..3978899) 1 NC_008595.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 3978899 ilvH 4528193 ilvH Mycobacterium avium 104 acetolactate synthase 3 regulatory subunit YP_883015.1 3978393 R 243243 CDS YP_883016.1 118464680 4528375 3981093..3981440 1 NC_008595.1 low molecular weight protein antigen 6 3981440 4528375 MAV_3853 Mycobacterium avium 104 low molecular weight protein antigen 6 YP_883016.1 3981093 D 243243 CDS YP_883017.1 118463083 4528906 complement(3981459..3982316) 1 NC_008595.1 identified by match to protein family HMM PF07681; DoxX subfamily protein, putative 3982316 4528906 MAV_3854 Mycobacterium avium 104 DoxX subfamily protein, putative YP_883017.1 3981459 R 243243 CDS YP_883018.1 118465069 4527045 3982608..3983678 1 NC_008595.1 LppZ protein 3983678 4527045 MAV_3855 Mycobacterium avium 104 LppZ protein YP_883018.1 3982608 D 243243 CDS YP_883019.1 118465520 4528937 complement(3983769..3985280) 1 NC_008595.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 3985280 gatB 4528937 gatB Mycobacterium avium 104 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_883019.1 3983769 R 243243 CDS YP_883020.1 118466600 4529366 complement(3985291..3986418) 1 NC_008595.1 hypothetical protein 3986418 4529366 MAV_3857 Mycobacterium avium 104 hypothetical protein YP_883020.1 3985291 R 243243 CDS YP_883021.1 118467293 4527251 complement(3986548..3987579) 1 NC_008595.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3987579 4527251 MAV_3858 Mycobacterium avium 104 6-phosphofructokinase YP_883021.1 3986548 R 243243 CDS YP_883022.1 118462655 4529082 complement(3987621..3989102) 1 NC_008595.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 3989102 gatA 4529082 gatA Mycobacterium avium 104 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_883022.1 3987621 R 243243 CDS YP_883023.1 118463284 4530532 complement(3989099..3989395) 1 NC_008595.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 3989395 gatC 4530532 gatC Mycobacterium avium 104 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_883023.1 3989099 R 243243 CDS YP_883024.1 118463139 4529664 3989513..3990178 1 NC_008595.1 identified by match to protein family HMM PF01842; ACT domain-containing protein 3990178 4529664 MAV_3861 Mycobacterium avium 104 ACT domain-containing protein YP_883024.1 3989513 D 243243 CDS YP_883025.1 118463581 4529766 complement(3990212..3990646) 1 NC_008595.1 hypothetical protein 3990646 4529766 MAV_3862 Mycobacterium avium 104 hypothetical protein YP_883025.1 3990212 R 243243 CDS YP_883026.1 118464293 4529581 complement(3990695..3993613) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL4 protein 3993613 4529581 MAV_3863 Mycobacterium avium 104 MmpL4 protein YP_883026.1 3990695 R 243243 CDS YP_883027.1 118465434 4527303 complement(3993610..3994056) 1 NC_008595.1 identified by match to protein family HMM PF05423; MmpS4 protein 3994056 4527303 MAV_3864 Mycobacterium avium 104 MmpS4 protein YP_883027.1 3993610 R 243243 CDS YP_883028.1 118462299 4525644 3994261..3994779 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 3994779 4525644 MAV_3865 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_883028.1 3994261 D 243243 CDS YP_883029.1 118462921 4526012 complement(3994790..3995380) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 3995380 4526012 MAV_3866 Mycobacterium avium 104 TetR family transcriptional regulator YP_883029.1 3994790 R 243243 CDS YP_883030.1 118463798 4525880 complement(3995466..3996578) 1 NC_008595.1 catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; cystathionine gamma-lyase 3996578 4525880 MAV_3867 Mycobacterium avium 104 cystathionine gamma-lyase YP_883030.1 3995466 R 243243 CDS YP_883031.1 118465270 4527291 complement(3996583..3998664) 1 NC_008595.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3998664 ligA 4527291 ligA Mycobacterium avium 104 NAD-dependent DNA ligase LigA YP_883031.1 3996583 R 243243 CDS YP_883032.1 118465803 4526116 complement(3998719..3999747) 1 NC_008595.1 identified by match to protein family HMM PF01717; methionine synthase, vitamin-B12 independent, putative 3999747 4526116 MAV_3869 Mycobacterium avium 104 methionine synthase, vitamin-B12 independent, putative YP_883032.1 3998719 R 243243 CDS YP_883033.1 118467226 4529783 complement(4000497..4001555) 1 NC_008595.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 4001555 mnmA 4529783 mnmA Mycobacterium avium 104 tRNA-specific 2-thiouridylase MnmA YP_883033.1 4000497 R 243243 CDS YP_883034.1 118463010 4526303 complement(4001574..4002752) 1 NC_008595.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; cysteine desulfurase 4002752 4526303 MAV_3872 Mycobacterium avium 104 cysteine desulfurase YP_883034.1 4001574 R 243243 CDS YP_883035.1 118463751 4527995 complement(4002786..4003667) 1 NC_008595.1 identified by match to protein family HMM PF01553; 1-acylglycerol-3-phosphate O-acyltransferase 4003667 4527995 MAV_3873 Mycobacterium avium 104 1-acylglycerol-3-phosphate O-acyltransferase YP_883035.1 4002786 R 243243 CDS YP_883036.1 118466273 4527825 complement(4003730..4004575) 1 NC_008595.1 hypothetical protein 4004575 4527825 MAV_3874 Mycobacterium avium 104 hypothetical protein YP_883036.1 4003730 R 243243 CDS YP_883037.1 118466694 4530436 complement(4004752..4005687) 1 NC_008595.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012; electron transfer flavoprotein, alpha subunit 4005687 4530436 MAV_3875 Mycobacterium avium 104 electron transfer flavoprotein, alpha subunit YP_883037.1 4004752 R 243243 CDS YP_883038.1 118467029 4526541 complement(4005748..4006539) 1 NC_008595.1 identified by match to protein family HMM PF01012; electron transfer protein, beta subunit 4006539 4526541 MAV_3876 Mycobacterium avium 104 electron transfer protein, beta subunit YP_883038.1 4005748 R 243243 CDS YP_883039.1 118464003 4529265 4006767..4007591 1 NC_008595.1 hypothetical protein 4007591 4529265 MAV_3877 Mycobacterium avium 104 hypothetical protein YP_883039.1 4006767 D 243243 CDS YP_883040.1 118464392 4528281 4007588..4009192 1 NC_008595.1 identified by match to protein family HMM PF03065; glycosyl hydrolase, family protein 57 4009192 4528281 MAV_3878 Mycobacterium avium 104 glycosyl hydrolase, family protein 57 YP_883040.1 4007588 D 243243 CDS YP_883041.1 118464974 4527466 4009209..4010465 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 4010465 4527466 MAV_3879 Mycobacterium avium 104 glycosyl transferase, group 1 family protein YP_883041.1 4009209 D 243243 CDS YP_883042.1 118466395 4526196 4010510..4011841 1 NC_008595.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01777; nucleoside-diphosphate sugar epimerase 4011841 4526196 MAV_3880 Mycobacterium avium 104 nucleoside-diphosphate sugar epimerase YP_883042.1 4010510 D 243243 CDS YP_883043.1 118466934 4527769 complement(4011893..4012564) 1 NC_008595.1 hypothetical protein 4012564 4527769 MAV_3881 Mycobacterium avium 104 hypothetical protein YP_883043.1 4011893 R 243243 CDS YP_883044.1 118467182 4530153 complement(4012641..4013375) 1 NC_008595.1 hypothetical protein 4013375 4530153 MAV_3882 Mycobacterium avium 104 hypothetical protein YP_883044.1 4012641 R 243243 CDS YP_883045.1 118464299 4529587 4013743..4014174 1 NC_008595.1 identified by match to protein family HMM PF01740; stas domain-containing protein 4014174 4529587 MAV_3883 Mycobacterium avium 104 stas domain-containing protein YP_883045.1 4013743 D 243243 CDS YP_883046.1 118465792 4526105 4014409..4015587 1 NC_008595.1 identified by match to protein family HMM PF00348; polyprenyl synthetase 4015587 4526105 MAV_3884 Mycobacterium avium 104 polyprenyl synthetase YP_883046.1 4014409 D 243243 CDS YP_883047.1 118466628 4526984 4015610..4017136 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593; match to protein family HMM TIGR02734; phytoene dehydrogenase 4017136 4526984 MAV_3885 Mycobacterium avium 104 phytoene dehydrogenase YP_883047.1 4015610 D 243243 CDS YP_883048.1 118467013 4529483 4017133..4018083 1 NC_008595.1 identified by match to protein family HMM PF00494; phytoene synthase 4018083 4529483 MAV_3886 Mycobacterium avium 104 phytoene synthase YP_883048.1 4017133 D 243243 CDS YP_883049.1 118462349 4527976 4018035..4018403 1 NC_008595.1 hypothetical protein 4018403 4527976 MAV_3887 Mycobacterium avium 104 hypothetical protein YP_883049.1 4018035 D 243243 CDS YP_883050.1 118462584 4530204 4018400..4018711 1 NC_008595.1 lycopene cyclase 4018711 4530204 MAV_3888 Mycobacterium avium 104 lycopene cyclase YP_883050.1 4018400 D 243243 CDS YP_883051.1 118462854 4526036 4018698..4019423 1 NC_008595.1 identified by match to protein family HMM PF01209; methyltransferase, UbiE/COQ5 family protein 4019423 4526036 MAV_3889 Mycobacterium avium 104 methyltransferase, UbiE/COQ5 family protein YP_883051.1 4018698 D 243243 CDS YP_883052.1 118463732 4528140 4019420..4020949 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593; dehydrogenase 4020949 4528140 MAV_3890 Mycobacterium avium 104 dehydrogenase YP_883052.1 4019420 D 243243 CDS YP_883053.1 118465419 4529968 4020946..4021956 1 NC_008595.1 identified by match to protein family HMM PF00355; methylesterase 4021956 4529968 MAV_3891 Mycobacterium avium 104 methylesterase YP_883053.1 4020946 D 243243 CDS YP_883054.1 118465130 4529161 4022024..4022350 1 NC_008595.1 hypothetical protein 4022350 4529161 MAV_3892 Mycobacterium avium 104 hypothetical protein YP_883054.1 4022024 D 243243 CDS YP_883055.1 118465884 4527918 4022351..4022917 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 4022917 4527918 MAV_3893 Mycobacterium avium 104 MarR family transcriptional regulator YP_883055.1 4022351 D 243243 CDS YP_883056.1 118465531 4530005 complement(4022959..4023993) 1 NC_008595.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 4023993 fni 4530005 fni Mycobacterium avium 104 isopentenyl pyrophosphate isomerase YP_883056.1 4022959 R 243243 CDS YP_883057.1 118462662 4529090 4024115..4026178 1 NC_008595.1 identified by match to protein family HMM PF03176; MmpL family protein 4026178 4529090 MAV_3895 Mycobacterium avium 104 MmpL family protein YP_883057.1 4024115 D 243243 CDS YP_883058.1 118464708 4529395 4026175..4026447 1 NC_008595.1 peripheral-type benzodiazepine receptor 4026447 4529395 MAV_3896 Mycobacterium avium 104 peripheral-type benzodiazepine receptor YP_883058.1 4026175 D 243243 CDS YP_883059.1 118464028 4528824 4026460..4027788 1 NC_008595.1 identified by match to protein family HMM PF00875; match to protein family HMM PF03441; Phr protein 4027788 4528824 MAV_3897 Mycobacterium avium 104 Phr protein YP_883059.1 4026460 D 243243 CDS YP_883060.1 118466574 4527363 complement(4027875..4028612) 1 NC_008595.1 identified by match to protein family HMM PF00132; hexapeptide transferase 4028612 4527363 MAV_3898 Mycobacterium avium 104 hexapeptide transferase YP_883060.1 4027875 R 243243 CDS YP_883061.1 118462460 4525633 4028765..4030036 1 NC_008595.1 hypothetical protein 4030036 4525633 MAV_3899 Mycobacterium avium 104 hypothetical protein YP_883061.1 4028765 D 243243 CDS YP_883062.1 118466847 4526956 4030260..4030433 1 NC_008595.1 hypothetical protein 4030433 4526956 MAV_3900 Mycobacterium avium 104 hypothetical protein YP_883062.1 4030260 D 243243 CDS YP_883063.1 118464356 4529158 complement(4030439..4031122) 1 NC_008595.1 immunogenic protein MPB64/MPT64 4031122 4529158 MAV_3901 Mycobacterium avium 104 immunogenic protein MPB64/MPT64 YP_883063.1 4030439 R 243243 CDS YP_883064.1 118463765 4528009 complement(4031195..4032370) 1 NC_008595.1 SAM-dependent methyltransferase 4032370 4528009 MAV_3902 Mycobacterium avium 104 SAM-dependent methyltransferase YP_883064.1 4031195 R 243243 CDS YP_883065.1 118465176 4528666 complement(4032371..4033342) 1 NC_008595.1 identified by match to protein family HMM PF01209; methyltransferase, UbiE/COQ5 family protein 4033342 4528666 MAV_3903 Mycobacterium avium 104 methyltransferase, UbiE/COQ5 family protein YP_883065.1 4032371 R 243243 CDS YP_883066.1 118463270 4528135 complement(4033354..4034127) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4034127 4528135 MAV_3904 Mycobacterium avium 104 enoyl-CoA hydratase YP_883066.1 4033354 R 243243 CDS YP_883067.1 118466372 4529934 complement(4034115..4034945) 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, nudix family protein, putative 4034945 4529934 MAV_3905 Mycobacterium avium 104 hydrolase, nudix family protein, putative YP_883067.1 4034115 R 243243 CDS YP_883068.1 118466981 4530380 complement(4034942..4035784) 1 NC_008595.1 identified by match to protein family HMM PF00005; molybdenum ABC transporter ATPase 4035784 4530380 MAV_3906 Mycobacterium avium 104 molybdenum ABC transporter ATPase YP_883068.1 4034942 R 243243 CDS YP_883069.1 118464260 4527445 complement(4035849..4037084) 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488; phosphoserine phosphatase SerB 4037084 serB 4527445 serB Mycobacterium avium 104 phosphoserine phosphatase SerB YP_883069.1 4035849 R 243243 CDS YP_883070.1 118464678 4528373 complement(4037109..4038740) 1 NC_008595.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02891; cytochrome C oxidase, subunit I 4038740 ctaD 4528373 ctaD Mycobacterium avium 104 cytochrome C oxidase, subunit I YP_883070.1 4037109 R 243243 CDS YP_883071.1 118465906 4528988 4038744..4039046 1 NC_008595.1 hypothetical protein 4039046 4528988 MAV_3909 Mycobacterium avium 104 hypothetical protein YP_883071.1 4038744 D 243243 CDS YP_883072.1 118463941 4526593 4039043..4040125 1 NC_008595.1 identified by match to protein family HMM PF01497; periplasmic binding protein 4040125 4526593 MAV_3910 Mycobacterium avium 104 periplasmic binding protein YP_883072.1 4039043 D 243243 CDS YP_883073.1 118466497 4525580 4040239..4041279 1 NC_008595.1 identified by match to protein family HMM PF00107; NADP-dependent alcohol dehydrogenase c 4041279 4525580 MAV_3911 Mycobacterium avium 104 NADP-dependent alcohol dehydrogenase c YP_883073.1 4040239 D 243243 CDS YP_883074.1 118467053 4526509 complement(4041290..4041703) 1 NC_008595.1 hypothetical protein 4041703 4526509 MAV_3912 Mycobacterium avium 104 hypothetical protein YP_883074.1 4041290 R 243243 CDS YP_883075.1 118465359 4529219 complement(4041784..4042758) 1 NC_008595.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 4042758 nrdF 4529219 nrdF Mycobacterium avium 104 ribonucleotide-diphosphate reductase subunit beta YP_883075.1 4041784 R 243243 CDS YP_883076.1 118467156 4527587 4042925..4043371 1 NC_008595.1 hypothetical protein 4043371 4527587 MAV_3914 Mycobacterium avium 104 hypothetical protein YP_883076.1 4042925 D 243243 CDS YP_883077.1 118463355 4529889 4043355..4043900 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4043900 4529889 MAV_3916 Mycobacterium avium 104 TetR family transcriptional regulator YP_883077.1 4043355 D 243243 CDS YP_883078.1 118466174 4526205 complement(4043883..4045421) 1 NC_008595.1 flavin-containing monooxygenase FMO 4045421 4526205 MAV_3915 Mycobacterium avium 104 flavin-containing monooxygenase FMO YP_883078.1 4043883 R 243243 CDS YP_883079.1 118462284 4529289 complement(4045578..4046327) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4046327 4529289 MAV_3917 Mycobacterium avium 104 TetR family transcriptional regulator YP_883079.1 4045578 R 243243 CDS YP_883080.1 118464604 4530115 complement(4046321..4046458) 1 NC_008595.1 hypothetical protein 4046458 4530115 MAV_3918 Mycobacterium avium 104 hypothetical protein YP_883080.1 4046321 R 243243 CDS YP_883081.1 118464322 4529827 complement(4046455..4048572) 1 NC_008595.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 4048572 4529827 MAV_3919 Mycobacterium avium 104 ribonucleotide-diphosphate reductase subunit alpha YP_883081.1 4046455 R 243243 CDS YP_883082.1 118465853 4530646 complement(4048590..4049042) 1 NC_008595.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 4049042 nrdI 4530646 nrdI Mycobacterium avium 104 ribonucleotide reductase stimulatory protein YP_883082.1 4048590 R 243243 CDS YP_883083.1 118465156 4529246 complement(4049085..4049324) 1 NC_008595.1 identified by match to protein family HMM PF00462; match to protein family HMM PF05768; match to protein family HMM TIGR02194; glutaredoxin 4049324 4529246 MAV_3921 Mycobacterium avium 104 glutaredoxin YP_883083.1 4049085 R 243243 CDS YP_883084.1 118467250 4526085 complement(4049855..4050385) 1 NC_008595.1 identified by match to protein family HMM PF03358; secreted protein 4050385 4526085 MAV_3922 Mycobacterium avium 104 secreted protein YP_883084.1 4049855 R 243243 CDS YP_883085.1 118466680 4530422 4050503..4051117 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4051117 4530422 MAV_3923 Mycobacterium avium 104 TetR family transcriptional regulator YP_883085.1 4050503 D 243243 CDS YP_883086.1 118465811 4525913 4051132..4052160 1 NC_008595.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 4052160 4525913 MAV_3925 Mycobacterium avium 104 DNA polymerase IV YP_883086.1 4051132 D 243243 CDS YP_883087.1 118462884 4527490 complement(4052095..4053027) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 4053027 4527490 MAV_3924 Mycobacterium avium 104 short chain dehydrogenase YP_883087.1 4052095 R 243243 CDS YP_883088.1 118465113 4530465 complement(4053059..4053694) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4053694 4530465 MAV_3926 Mycobacterium avium 104 TetR family transcriptional regulator YP_883088.1 4053059 R 243243 CDS YP_883089.1 118466912 4529457 4053811..4055289 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome p450 4055289 4529457 MAV_3927 Mycobacterium avium 104 cytochrome p450 YP_883089.1 4053811 D 243243 CDS YP_883090.1 118462891 4527498 complement(4055329..4055853) 1 NC_008595.1 hypothetical protein 4055853 4527498 MAV_3928 Mycobacterium avium 104 hypothetical protein YP_883090.1 4055329 R 243243 CDS YP_883091.1 118464999 4526265 4056155..4056343 1 NC_008595.1 hypothetical protein 4056343 4526265 MAV_3929 Mycobacterium avium 104 hypothetical protein YP_883091.1 4056155 D 243243 CDS YP_883092.1 118463416 4530053 4056825..4056959 1 NC_008595.1 hypothetical protein 4056959 4530053 MAV_3930 Mycobacterium avium 104 hypothetical protein YP_883092.1 4056825 D 243243 CDS YP_883093.1 118464344 4529146 complement(4057012..4058004) 1 NC_008595.1 regulator of Sig8 4058004 4529146 MAV_3931 Mycobacterium avium 104 regulator of Sig8 YP_883093.1 4057012 R 243243 CDS YP_883094.1 118463771 4530122 complement(4058101..4059558) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 4059558 4530122 MAV_3932 Mycobacterium avium 104 GntR family transcriptional regulator YP_883094.1 4058101 R 243243 CDS YP_883095.1 118465193 4530390 4060825..4061160 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 4061160 4530390 MAV_3934 Mycobacterium avium 104 hypothetical protein YP_883095.1 4060825 D 243243 CDS YP_883096.1 118467305 4530297 complement(4061186..4063351) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; acyl-CoA dehydrogenase 4063351 4530297 MAV_3935 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883096.1 4061186 R 243243 CDS YP_883097.1 118465806 4526119 complement(4063463..4064221) 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-hydroxyacyl-CoA dehydrogenase type-2 4064221 4526119 MAV_3936 Mycobacterium avium 104 3-hydroxyacyl-CoA dehydrogenase type-2 YP_883097.1 4063463 R 243243 CDS YP_883098.1 118463279 4530527 4064305..4065885 1 NC_008595.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase 4065885 ligB 4530527 ligB Mycobacterium avium 104 ATP-dependent DNA ligase YP_883098.1 4064305 D 243243 CDS YP_883099.1 118462556 4530557 4065935..4068211 1 NC_008595.1 identified by match to protein family HMM PF02554; carbon starvation protein A 4068211 4530557 MAV_3938 Mycobacterium avium 104 carbon starvation protein A YP_883099.1 4065935 D 243243 CDS YP_883100.1 118466386 4526187 4068221..4069738 1 NC_008595.1 identified by match to protein family HMM PF00012; DnaK family protein 4069738 4526187 MAV_3939 Mycobacterium avium 104 DnaK family protein YP_883100.1 4068221 D 243243 CDS YP_883101.1 118463654 4528556 complement(4070716..4070916) 1 NC_008595.1 sensor protein AtoS 4070916 4528556 MAV_3941 Mycobacterium avium 104 sensor protein AtoS YP_883101.1 4070716 R 243243 CDS YP_883102.1 118465962 4528181 4070935..4071717 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 4071717 4528181 MAV_3942 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_883102.1 4070935 D 243243 CDS YP_883103.1 118465151 4529241 4071742..4073037 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4073037 4529241 MAV_3944 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883103.1 4071742 D 243243 CDS YP_883104.1 118464476 4528850 complement(4073034..4073717) 1 NC_008595.1 hypothetical protein 4073717 4528850 MAV_3943 Mycobacterium avium 104 hypothetical protein YP_883104.1 4073034 R 243243 CDS YP_883105.1 118463785 4530136 4073899..4074144 1 NC_008595.1 hypothetical protein 4074144 4530136 MAV_3945 Mycobacterium avium 104 hypothetical protein YP_883105.1 4073899 D 243243 CDS YP_883106.1 118467335 4526973 complement(4074148..4075122) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein, putative 4075122 4526973 MAV_3946 Mycobacterium avium 104 phosphotransferase enzyme family protein, putative YP_883106.1 4074148 R 243243 CDS YP_883107.1 118465234 4525605 complement(4075119..4075925) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 4075925 4525605 MAV_3947 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_883107.1 4075119 R 243243 CDS YP_883108.1 118466266 4527818 complement(4076004..4076921) 1 NC_008595.1 hypothetical protein 4076921 4527818 MAV_3948 Mycobacterium avium 104 hypothetical protein YP_883108.1 4076004 R 243243 CDS YP_883109.1 118462364 4527992 4076964..4077308 1 NC_008595.1 identified by similarity to SP:Q57225; match to protein family HMM PF00893; transporter, small multidrug resistance (SMR) family protein 4077308 4527992 MAV_3949 Mycobacterium avium 104 transporter, small multidrug resistance (SMR) family protein YP_883109.1 4076964 D 243243 CDS YP_883110.1 118462885 4527492 4077403..4078782 1 NC_008595.1 hypothetical protein 4078782 4527492 MAV_3950 Mycobacterium avium 104 hypothetical protein YP_883110.1 4077403 D 243243 CDS YP_883111.1 118463769 4530120 4078814..4078999 1 NC_008595.1 hypothetical protein 4078999 4530120 MAV_3951 Mycobacterium avium 104 hypothetical protein YP_883111.1 4078814 D 243243 CDS YP_883112.1 118464390 4528279 4078992..4079417 1 NC_008595.1 hypothetical protein 4079417 4528279 MAV_3952 Mycobacterium avium 104 hypothetical protein YP_883112.1 4078992 D 243243 CDS YP_883113.1 118463729 4528079 4079590..4080006 1 NC_008595.1 identified by match to protein family HMM PF05423; MmpS2 protein 4080006 4528079 MAV_3953 Mycobacterium avium 104 MmpS2 protein YP_883113.1 4079590 D 243243 CDS YP_883114.1 118465378 4529669 4082893..4084374 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter 4084374 4529669 MAV_3955 Mycobacterium avium 104 ABC transporter YP_883114.1 4082893 D 243243 CDS YP_883115.1 118467064 4526442 4084419..4085774 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF02361; cobalt transport protein, putative 4085774 4526442 MAV_3956 Mycobacterium avium 104 cobalt transport protein, putative YP_883115.1 4084419 D 243243 CDS YP_883116.1 118462385 4525928 complement(4085783..4087063) 1 NC_008595.1 identified by match to protein family HMM PF00113; match to protein family HMM PF03952; enolase 4087063 4525928 MAV_3957 Mycobacterium avium 104 enolase YP_883116.1 4085783 R 243243 CDS YP_883117.1 118464298 4529586 complement(4087148..4087705) 1 NC_008595.1 identified by match to protein family HMM PF02627; hypothetical protein 4087705 pcaC 4529586 pcaC Mycobacterium avium 104 hypothetical protein YP_883117.1 4087148 R 243243 CDS YP_883118.1 118467299 4527258 complement(4087707..4088552) 1 NC_008595.1 identified by match to protein family HMM PF02668; taurine catabolism dioxygenase TauD, TfdA family protein 4088552 4527258 MAV_3959 Mycobacterium avium 104 taurine catabolism dioxygenase TauD, TfdA family protein YP_883118.1 4087707 R 243243 CDS YP_883119.1 118464890 4529619 complement(4088598..4088936) 1 NC_008595.1 hypothetical protein 4088936 4529619 MAV_3960 Mycobacterium avium 104 hypothetical protein YP_883119.1 4088598 R 243243 CDS YP_883120.1 118466580 4527370 complement(4088933..4090195) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 4090195 4527370 MAV_3961 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_883120.1 4088933 R 243243 CDS YP_883121.1 118465832 4525504 complement(4090192..4090950) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD-dependent epimerase/dehydratase:short chain dehydrogenase/reductase SDR 4090950 4525504 MAV_3962 Mycobacterium avium 104 NAD-dependent epimerase/dehydratase:short chain dehydrogenase/reductase SDR YP_883121.1 4090192 R 243243 CDS YP_883122.1 118465166 4528656 complement(4090947..4091768) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; 2Fe-2S iron-sulfur cluster binding domain-containing protein 4091768 4528656 MAV_3963 Mycobacterium avium 104 2Fe-2S iron-sulfur cluster binding domain-containing protein YP_883122.1 4090947 R 243243 CDS YP_883123.1 118464455 4527048 complement(4091835..4092287) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 4092287 4527048 MAV_3964 Mycobacterium avium 104 MarR family transcriptional regulator YP_883123.1 4091835 R 243243 CDS YP_883124.1 118465771 4526906 complement(4093543..4093878) 1 NC_008595.1 hypothetical protein 4093878 4526906 MAV_3966 Mycobacterium avium 104 hypothetical protein YP_883124.1 4093543 R 243243 CDS YP_883125.1 118462998 4530628 complement(4093875..4095143) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 4095143 4530628 MAV_3967 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_883125.1 4093875 R 243243 CDS YP_883126.1 118467278 4527080 4095308..4096750 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 4096750 4527080 MAV_3969 Mycobacterium avium 104 aldehyde dehydrogenase YP_883126.1 4095308 D 243243 CDS YP_883127.1 118464084 4528397 complement(4096747..4096941) 1 NC_008595.1 long chain fatty acid-CoA synthetase Faa4p 4096941 4528397 MAV_3968 Mycobacterium avium 104 long chain fatty acid-CoA synthetase Faa4p YP_883127.1 4096747 R 243243 CDS YP_883128.1 118466561 4529110 4097240..4097383 1 NC_008595.1 hypothetical protein 4097383 4529110 MAV_3970 Mycobacterium avium 104 hypothetical protein YP_883128.1 4097240 D 243243 CDS YP_883129.1 118464728 4529415 complement(4097430..4097813) 1 NC_008595.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550; death-on-curing protein 4097813 4529415 MAV_3971 Mycobacterium avium 104 death-on-curing protein YP_883129.1 4097430 R 243243 CDS YP_883130.1 118462604 4528508 complement(4097810..4097941) 1 NC_008595.1 hypothetical protein 4097941 4528508 MAV_3972 Mycobacterium avium 104 hypothetical protein YP_883130.1 4097810 R 243243 CDS YP_883131.1 118464144 4528846 complement(4098224..4099405) 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; permease of the major facilitator superfamily protein 4099405 4528846 MAV_3974 Mycobacterium avium 104 permease of the major facilitator superfamily protein YP_883131.1 4098224 R 243243 CDS YP_883132.1 118466730 4530668 4101242..4101640 1 NC_008595.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 4101640 4530668 MAV_3976 Mycobacterium avium 104 camphor resistance protein CrcB YP_883132.1 4101242 D 243243 CDS YP_883133.1 118466370 4529932 4101637..4102005 1 NC_008595.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 4102005 4529932 MAV_3977 Mycobacterium avium 104 camphor resistance protein CrcB YP_883133.1 4101637 D 243243 CDS YP_883134.1 118465292 4529328 complement(4102016..4102642) 1 NC_008595.1 hypothetical protein 4102642 4529328 MAV_3978 Mycobacterium avium 104 hypothetical protein YP_883134.1 4102016 R 243243 CDS YP_883135.1 118464803 4527622 complement(4102664..4102996) 1 NC_008595.1 identified by match to protein family HMM PF04343; hypothetical protein 4102996 4527622 MAV_3979 Mycobacterium avium 104 hypothetical protein YP_883135.1 4102664 R 243243 CDS YP_883136.1 118464996 4526262 4103089..4104348 1 NC_008595.1 hypothetical protein 4104348 4526262 MAV_3980 Mycobacterium avium 104 hypothetical protein YP_883136.1 4103089 D 243243 CDS YP_883137.1 118465837 4525509 complement(4104353..4105273) 1 NC_008595.1 identified by match to protein family HMM PF03328; HpcH/HpaI aldolase/citrate lyase, putative 4105273 4525509 MAV_3981 Mycobacterium avium 104 HpcH/HpaI aldolase/citrate lyase, putative YP_883137.1 4104353 R 243243 CDS YP_883138.1 118466106 4527735 4105557..4106120 1 NC_008595.1 identified by match to protein family HMM PF01814; hemerythrin HHE cation binding domain-containing protein 4106120 4527735 MAV_3982 Mycobacterium avium 104 hemerythrin HHE cation binding domain-containing protein YP_883138.1 4105557 D 243243 CDS YP_883139.1 118466965 4530364 4106156..4107631 1 NC_008595.1 identified by match to protein family HMM PF02696; hypothetical protein 4107631 4530364 MAV_3983 Mycobacterium avium 104 hypothetical protein YP_883139.1 4106156 D 243243 CDS YP_883140.1 118463425 4528304 complement(4107639..4108046) 1 NC_008595.1 hypothetical protein 4108046 4528304 MAV_3984 Mycobacterium avium 104 hypothetical protein YP_883140.1 4107639 R 243243 CDS YP_883141.1 118463851 4529950 complement(4108105..4108377) 1 NC_008595.1 hypothetical protein 4108377 4529950 MAV_3985 Mycobacterium avium 104 hypothetical protein YP_883141.1 4108105 R 243243 CDS YP_883142.1 118464865 4530701 complement(4108392..4108988) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4108988 4530701 MAV_3986 Mycobacterium avium 104 TetR family transcriptional regulator YP_883142.1 4108392 R 243243 CDS YP_883143.1 118465291 4529327 4109086..4110090 1 NC_008595.1 hypothetical protein 4110090 4529327 MAV_3987 Mycobacterium avium 104 hypothetical protein YP_883143.1 4109086 D 243243 CDS YP_883144.1 118465687 4525746 complement(4110100..4110495) 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 4110495 4525746 MAV_3988 Mycobacterium avium 104 hypothetical protein YP_883144.1 4110100 R 243243 CDS YP_883145.1 118463121 4529646 4110487..4111947 1 NC_008595.1 identified by match to protein family HMM PF00614; phospholipase D family protein 4111947 4529646 MAV_3989 Mycobacterium avium 104 phospholipase D family protein YP_883145.1 4110487 D 243243 CDS YP_883146.1 118467270 4527072 4112027..4112890 1 NC_008595.1 identified by match to protein family HMM PF05721; phytanoyl-CoA dioxygenase (PhyH) family protein 4112890 4527072 MAV_3990 Mycobacterium avium 104 phytanoyl-CoA dioxygenase (PhyH) family protein YP_883146.1 4112027 D 243243 CDS YP_883147.1 118465211 4529848 complement(4112908..4114353) 1 NC_008595.1 identified by match to protein family HMM PF00144; beta-lactamase 4114353 4529848 MAV_3991 Mycobacterium avium 104 beta-lactamase YP_883147.1 4112908 R 243243 CDS YP_883148.1 118465971 4528190 4115131..4115637 1 NC_008595.1 hypothetical protein 4115637 4528190 MAV_3993 Mycobacterium avium 104 hypothetical protein YP_883148.1 4115131 D 243243 CDS YP_883149.1 118463679 4528526 4115744..4116814 1 NC_008595.1 glycosyltransferase GtfB 4116814 4528526 MAV_3994 Mycobacterium avium 104 glycosyltransferase GtfB YP_883149.1 4115744 D 243243 CDS YP_883150.1 118464244 4527429 complement(4116819..4117544) 1 NC_008595.1 hypothetical protein 4117544 4527429 MAV_3995 Mycobacterium avium 104 hypothetical protein YP_883150.1 4116819 R 243243 CDS YP_883151.1 118466468 4528690 complement(4118271..4119545) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 4119545 4528690 MAV_3996 Mycobacterium avium 104 transposase, Mutator family protein YP_883151.1 4118271 R 243243 CDS YP_883152.1 118467062 4526440 complement(4119594..4119902) 1 NC_008595.1 hypothetical protein 4119902 4526440 MAV_3997 Mycobacterium avium 104 hypothetical protein YP_883152.1 4119594 R 243243 CDS YP_883153.1 118462930 4526021 complement(4121466..4122212) 1 NC_008595.1 identified by match to protein family HMM PF00892; hypothetical protein 4122212 4526021 MAV_4000 Mycobacterium avium 104 hypothetical protein YP_883153.1 4121466 R 243243 CDS YP_883154.1 118462231 4525568 complement(4122305..4122466) 1 NC_008595.1 SsrA-binding protein 4122466 4525568 MAV_4001 Mycobacterium avium 104 SsrA-binding protein YP_883154.1 4122305 R 243243 CDS YP_883155.1 118464735 4529422 complement(4122817..4123710) 1 NC_008595.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 4123710 4529422 MAV_4002 Mycobacterium avium 104 efflux ABC transporter permease YP_883155.1 4122817 R 243243 CDS YP_883156.1 118466009 4528454 complement(4123711..4124403) 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00960; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 4124403 ftsE 4528454 ftsE Mycobacterium avium 104 cell division ATP-binding protein FtsE YP_883156.1 4123711 R 243243 CDS YP_883157.1 118465405 4525665 complement(4124445..4124945) 1 NC_008595.1 hypothetical protein 4124945 4525665 MAV_4004 Mycobacterium avium 104 hypothetical protein YP_883157.1 4124445 R 243243 CDS YP_883158.1 118466985 4529512 complement(4124942..4125820) 1 NC_008595.1 identified by match to protein family HMM PF00924; transporter, small conductance mechanosensitive ion channel (MscS) family protein 4125820 4529512 MAV_4005 Mycobacterium avium 104 transporter, small conductance mechanosensitive ion channel (MscS) family protein YP_883158.1 4124942 R 243243 CDS YP_883159.1 118467007 4529477 complement(4125927..4127039) 1 NC_008595.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 4127039 prfB 4529477 prfB Mycobacterium avium 104 peptide chain release factor 2 YP_883159.1 4125927 R 243243 CDS YP_883160.1 118466292 4529538 4127212..4128579 1 NC_008595.1 NADPH-ferredoxin reductase fpra 4128579 4529538 MAV_4007 Mycobacterium avium 104 NADPH-ferredoxin reductase fpra YP_883160.1 4127212 D 243243 CDS YP_883161.1 118464826 4529728 4128651..4129082 1 NC_008595.1 hypothetical protein 4129082 4529728 MAV_4009 Mycobacterium avium 104 hypothetical protein YP_883161.1 4128651 D 243243 CDS YP_883162.1 118466963 4530362 complement(4129024..4129488) 1 NC_008595.1 hypothetical protein 4129488 4530362 MAV_4008 Mycobacterium avium 104 hypothetical protein YP_883162.1 4129024 R 243243 CDS YP_883163.1 118464029 4528826 complement(4129508..4130266) 1 NC_008595.1 hypothetical protein 4130266 4528826 MAV_4010 Mycobacterium avium 104 hypothetical protein YP_883163.1 4129508 R 243243 CDS YP_883164.1 118463641 4528543 4130607..4132850 1 NC_008595.1 nitric-oxide reductase subunit B 4132850 4528543 MAV_4011 Mycobacterium avium 104 nitric-oxide reductase subunit B YP_883164.1 4130607 D 243243 CDS YP_883165.1 118464767 4529122 4132854..4133480 1 NC_008595.1 hypothetical protein 4133480 4529122 MAV_4012 Mycobacterium avium 104 hypothetical protein YP_883165.1 4132854 D 243243 CDS YP_883166.1 118462728 4527799 4133477..4134274 1 NC_008595.1 identified by match to protein family HMM PF01145; SPFH domain-containing protein/band 7 family protein 4134274 4527799 MAV_4013 Mycobacterium avium 104 SPFH domain-containing protein/band 7 family protein YP_883166.1 4133477 D 243243 CDS YP_883167.1 118463069 4527568 4134717..4135892 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4135892 4527568 MAV_4014 Mycobacterium avium 104 PPE family protein YP_883167.1 4134717 D 243243 CDS YP_883168.1 118466535 4527003 4135989..4137077 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4137077 4527003 MAV_4015 Mycobacterium avium 104 PPE family protein YP_883168.1 4135989 D 243243 CDS YP_883169.1 118466283 4529529 complement(4137081..4137434) 1 NC_008595.1 hypothetical protein 4137434 4529529 MAV_4016 Mycobacterium avium 104 hypothetical protein YP_883169.1 4137081 R 243243 CDS YP_883170.1 118466961 4530273 4137511..4138290 1 NC_008595.1 identified by match to protein family HMM PF00459; match to protein family HMM TIGR02067; inositol monophosphatase 4138290 4530273 MAV_4017 Mycobacterium avium 104 inositol monophosphatase YP_883170.1 4137511 D 243243 CDS YP_883171.1 118466268 4527820 4138376..4139767 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4139767 4527820 MAV_4018 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883171.1 4138376 D 243243 CDS YP_883172.1 118466732 4530670 4139803..4141008 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4141008 4530670 MAV_4019 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883172.1 4139803 D 243243 CDS YP_883173.1 118463306 4526001 4141039..4141155 1 NC_008595.1 hypothetical protein 4141155 4526001 MAV_4020 Mycobacterium avium 104 hypothetical protein YP_883173.1 4141039 D 243243 CDS YP_883174.1 118467183 4530154 4141178..4142149 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 4142149 4530154 MAV_4021 Mycobacterium avium 104 zinc-binding dehydrogenase YP_883174.1 4141178 D 243243 CDS YP_883175.1 118465665 4526737 4142257..4143351 1 NC_008595.1 identified by match to protein family HMM PF04209; homogentisate 1,2-dioxygenase 4143351 hmgA 4526737 hmgA Mycobacterium avium 104 homogentisate 1,2-dioxygenase YP_883175.1 4142257 D 243243 CDS YP_883176.1 118465917 4528999 4143351..4144526 1 NC_008595.1 hypothetical protein 4144526 4528999 MAV_4023 Mycobacterium avium 104 hypothetical protein YP_883176.1 4143351 D 243243 CDS YP_883177.1 118463893 4530570 4144523..4145737 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 4145737 4530570 MAV_4024 Mycobacterium avium 104 caib/baif family protein YP_883177.1 4144523 D 243243 CDS YP_883178.1 118464166 4526476 4145746..4146639 1 NC_008595.1 identified by match to protein family HMM PF00682; pyruvate carboxyltransferase 4146639 4526476 MAV_4025 Mycobacterium avium 104 pyruvate carboxyltransferase YP_883178.1 4145746 D 243243 CDS YP_883179.1 118462296 4525641 4146654..4147265 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4147265 4525641 MAV_4026 Mycobacterium avium 104 TetR family transcriptional regulator YP_883179.1 4146654 D 243243 CDS YP_883180.1 118463134 4529659 4147276..4148514 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4148514 4529659 MAV_4027 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883180.1 4147276 D 243243 CDS YP_883181.1 118466175 4526206 4148514..4149512 1 NC_008595.1 identified by match to protein family HMM PF01636; aminoglycoside phosphotransferase 4149512 4526206 MAV_4028 Mycobacterium avium 104 aminoglycoside phosphotransferase YP_883181.1 4148514 D 243243 CDS YP_883182.1 118464164 4526474 4149512..4149850 1 NC_008595.1 hypothetical protein 4149850 4526474 MAV_4029 Mycobacterium avium 104 hypothetical protein YP_883182.1 4149512 D 243243 CDS YP_883183.1 118465319 4526515 4150310..4150837 1 NC_008595.1 identified by match to protein family HMM PF04264; YceI like family protein 4150837 4526515 MAV_4031 Mycobacterium avium 104 YceI like family protein YP_883183.1 4150310 D 243243 CDS YP_883184.1 118464776 4529131 4150899..4151312 1 NC_008595.1 two-component system response regulator 4151312 4529131 MAV_4032 Mycobacterium avium 104 two-component system response regulator YP_883184.1 4150899 D 243243 CDS YP_883185.1 118466422 4530166 4151467..4151931 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 4151931 nuoA 4530166 nuoA Mycobacterium avium 104 NADH dehydrogenase subunit A YP_883185.1 4151467 D 243243 CDS YP_883186.1 118465722 4527457 4151957..4152511 1 NC_008595.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 4152511 4527457 MAV_4034 Mycobacterium avium 104 NADH dehydrogenase subunit B YP_883186.1 4151957 D 243243 CDS YP_883187.1 118462470 4528724 4152508..4153215 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 4153215 4528724 MAV_4035 Mycobacterium avium 104 NADH dehydrogenase subunit C YP_883187.1 4152508 D 243243 CDS YP_883188.1 118466708 4529715 4153215..4154540 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 4154540 nuoD 4529715 nuoD Mycobacterium avium 104 NADH dehydrogenase subunit D YP_883188.1 4153215 D 243243 CDS YP_883189.1 118463625 4527329 4154537..4155295 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 4155295 4527329 MAV_4037 Mycobacterium avium 104 NADH dehydrogenase subunit E YP_883189.1 4154537 D 243243 CDS YP_883190.1 118462706 4526687 4155292..4156653 1 NC_008595.1 identified by match to protein family HMM PF01512; match to protein family HMM TIGR01959; NADH-quinone oxidoreductase, F subunit 4156653 nuoF 4526687 nuoF Mycobacterium avium 104 NADH-quinone oxidoreductase, F subunit YP_883190.1 4155292 D 243243 CDS YP_883191.1 118462718 4530092 4156680..4159061 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 4159061 4530092 MAV_4039 Mycobacterium avium 104 NADH dehydrogenase subunit G YP_883191.1 4156680 D 243243 CDS YP_883192.1 118467241 4529798 4159058..4160314 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 4160314 4529798 MAV_4040 Mycobacterium avium 104 NADH dehydrogenase subunit H YP_883192.1 4159058 D 243243 CDS YP_883193.1 118466656 4528095 4160326..4160871 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 4160871 4528095 MAV_4041 Mycobacterium avium 104 NADH dehydrogenase subunit I YP_883193.1 4160326 D 243243 CDS YP_883194.1 118465874 4527516 4160868..4161692 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 4161692 4527516 MAV_4042 Mycobacterium avium 104 NADH dehydrogenase subunit J YP_883194.1 4160868 D 243243 CDS YP_883195.1 118464397 4530791 4161689..4161988 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 4161988 nuoK 4530791 nuoK Mycobacterium avium 104 NADH dehydrogenase subunit K YP_883195.1 4161689 D 243243 CDS YP_883196.1 118463741 4528149 4161963..4163885 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 4163885 4528149 MAV_4044 Mycobacterium avium 104 NADH dehydrogenase subunit L YP_883196.1 4161963 D 243243 CDS YP_883197.1 118462860 4527087 4163882..4165450 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 4165450 4527087 MAV_4045 Mycobacterium avium 104 NADH dehydrogenase subunit M YP_883197.1 4163882 D 243243 CDS YP_883198.1 118467245 4529802 4165447..4167030 1 NC_008595.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 4167030 4529802 MAV_4047 Mycobacterium avium 104 NADH dehydrogenase subunit N YP_883198.1 4165447 D 243243 CDS YP_883199.1 118462312 4529630 complement(4166957..4167649) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4167649 4529630 MAV_4046 Mycobacterium avium 104 TetR family transcriptional regulator YP_883199.1 4166957 R 243243 CDS YP_883200.1 118466483 4527613 4167728..4168558 1 NC_008595.1 identified by match to protein family HMM PF02409; Omt protein 4168558 4527613 MAV_4048 Mycobacterium avium 104 Omt protein YP_883200.1 4167728 D 243243 CDS YP_883201.1 118463088 4528911 complement(4168616..4169068) 1 NC_008595.1 hypothetical protein 4169068 4528911 MAV_4049 Mycobacterium avium 104 hypothetical protein YP_883201.1 4168616 R 243243 CDS YP_883202.1 118463519 4527699 complement(4169061..4170176) 1 NC_008595.1 identified by match to protein family HMM PF01882; hypothetical protein 4170176 4527699 MAV_4050 Mycobacterium avium 104 hypothetical protein YP_883202.1 4169061 R 243243 CDS YP_883203.1 118464433 4530254 complement(4170203..4170319) 1 NC_008595.1 hypothetical protein 4170319 4530254 MAV_4051 Mycobacterium avium 104 hypothetical protein YP_883203.1 4170203 R 243243 CDS YP_883204.1 118462684 4530612 complement(4170327..4171241) 1 NC_008595.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728; ATPase 4171241 4530612 MAV_4052 Mycobacterium avium 104 ATPase YP_883204.1 4170327 R 243243 CDS YP_883205.1 118466660 4526610 complement(4171324..4171794) 1 NC_008595.1 hypothetical protein 4171794 4526610 MAV_4053 Mycobacterium avium 104 hypothetical protein YP_883205.1 4171324 R 243243 CDS YP_883206.1 118466236 4526582 complement(4171803..4172765) 1 NC_008595.1 hypothetical protein 4172765 4526582 MAV_4054 Mycobacterium avium 104 hypothetical protein YP_883206.1 4171803 R 243243 CDS YP_883207.1 118466803 4529049 4172936..4174318 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 4174318 4529049 MAV_4055 Mycobacterium avium 104 hypothetical protein YP_883207.1 4172936 D 243243 CDS YP_883208.1 118464821 4527640 complement(4174536..4175921) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 4175921 4527640 MAV_4056 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_883208.1 4174536 R 243243 CDS YP_883209.1 118463974 4527221 complement(4175918..4176520) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4176520 4527221 MAV_4057 Mycobacterium avium 104 TetR family transcriptional regulator YP_883209.1 4175918 R 243243 CDS YP_883210.1 118463395 4528022 4176578..4177711 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 4177711 4528022 MAV_4058 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_883210.1 4176578 D 243243 CDS YP_883211.1 118466788 4529346 4177711..4178826 1 NC_008595.1 hypothetical protein 4178826 4529346 MAV_4060 Mycobacterium avium 104 hypothetical protein YP_883211.1 4177711 D 243243 CDS YP_883212.1 118466382 4526183 complement(4178809..4181499) 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; monoxygenase 4181499 4526183 MAV_4059 Mycobacterium avium 104 monoxygenase YP_883212.1 4178809 R 243243 CDS YP_883213.1 118467184 4530155 4181633..4182979 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593; flavin-containing monoamine oxidase AofH 4182979 4530155 MAV_4062 Mycobacterium avium 104 flavin-containing monoamine oxidase AofH YP_883213.1 4181633 D 243243 CDS YP_883214.1 118465588 4527135 complement(4182974..4183924) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4183924 4527135 MAV_4061 Mycobacterium avium 104 alpha/beta hydrolase YP_883214.1 4182974 R 243243 CDS YP_883215.1 118466006 4528450 complement(4184042..4185118) 1 NC_008595.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4185118 4528450 MAV_4063 Mycobacterium avium 104 AraC family transcriptional regulator YP_883215.1 4184042 R 243243 CDS YP_883216.1 118463829 4526047 complement(4185153..4186325) 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 4186325 4526047 MAV_4064 Mycobacterium avium 104 glycosyl transferase, group 1 family protein YP_883216.1 4185153 R 243243 CDS YP_883217.1 118464684 4528379 4186462..4187379 1 NC_008595.1 identified by match to protein family HMM PF01339; protein-glutamate methylesterase CheB 4187379 cheB 4528379 cheB Mycobacterium avium 104 protein-glutamate methylesterase CheB YP_883217.1 4186462 D 243243 CDS YP_883218.1 118462298 4525643 complement(4187376..4189226) 1 NC_008595.1 identified by match to protein family HMM PF00989; match to protein family HMM PF01739; match to protein family HMM PF03705; match to protein family HMM TIGR00229; CheR methyltransferase SAM binding domain-containing protein 4189226 cheR 4525643 cheR Mycobacterium avium 104 CheR methyltransferase SAM binding domain-containing protein YP_883218.1 4187376 R 243243 CDS YP_883219.1 118465250 4528468 complement(4189279..4190037) 1 NC_008595.1 identified by match to protein family HMM PF01740; stas domain-containing protein 4190037 4528468 MAV_4067 Mycobacterium avium 104 stas domain-containing protein YP_883219.1 4189279 R 243243 CDS YP_883220.1 118464864 4530700 4191134..4193299 1 NC_008595.1 identified by similarity to SP:P21179; match to protein family HMM PF00199; match to protein family HMM PF01965; match to protein family HMM PF06628; catalase HPII 4193299 katE 4530700 katE Mycobacterium avium 104 catalase HPII YP_883220.1 4191134 D 243243 CDS YP_883221.1 118465882 4527916 4193389..4193646 1 NC_008595.1 hypothetical protein 4193646 4527916 MAV_4070 Mycobacterium avium 104 hypothetical protein YP_883221.1 4193389 D 243243 CDS YP_883222.1 118466992 4529519 complement(4193651..4194226) 1 NC_008595.1 hypothetical protein 4194226 4529519 MAV_4071 Mycobacterium avium 104 hypothetical protein YP_883222.1 4193651 R 243243 CDS YP_883223.1 118463903 4525834 4194377..4194544 1 NC_008595.1 hypothetical protein 4194544 4525834 MAV_4072 Mycobacterium avium 104 hypothetical protein YP_883223.1 4194377 D 243243 CDS YP_883224.1 118463412 4530049 4194541..4195494 1 NC_008595.1 dehydrogenase 4195494 4530049 MAV_4073 Mycobacterium avium 104 dehydrogenase YP_883224.1 4194541 D 243243 CDS YP_883225.1 118462938 4530223 4195491..4196258 1 NC_008595.1 identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase 4196258 4530223 MAV_4074 Mycobacterium avium 104 GlcNAc-PI de-N-acetylase YP_883225.1 4195491 D 243243 CDS YP_883226.1 118462542 4530543 4196327..4197085 1 NC_008595.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase 4197085 4530543 MAV_4076 Mycobacterium avium 104 endonuclease/exonuclease/phosphatase YP_883226.1 4196327 D 243243 CDS YP_883227.1 118467124 4526151 complement(4197049..4197360) 1 NC_008595.1 hypothetical protein 4197360 4526151 MAV_4075 Mycobacterium avium 104 hypothetical protein YP_883227.1 4197049 R 243243 CDS YP_883228.1 118464715 4529402 complement(4197504..4197740) 1 NC_008595.1 hypothetical protein 4197740 4529402 MAV_4077 Mycobacterium avium 104 hypothetical protein YP_883228.1 4197504 R 243243 CDS YP_883229.1 118463673 4525965 4197965..4198822 1 NC_008595.1 hypothetical protein 4198822 4525965 MAV_4078 Mycobacterium avium 104 hypothetical protein YP_883229.1 4197965 D 243243 CDS YP_883230.1 118465779 4526914 4199055..4199453 1 NC_008595.1 hypothetical protein 4199453 4526914 MAV_4079 Mycobacterium avium 104 hypothetical protein YP_883230.1 4199055 D 243243 CDS YP_883231.1 118464831 4529736 4201011..4201937 1 NC_008595.1 transferase 4201937 4529736 MAV_4081 Mycobacterium avium 104 transferase YP_883231.1 4201011 D 243243 CDS YP_883232.1 118467323 4526961 4201955..4203175 1 NC_008595.1 identified by match to protein family HMM PF00534; transferase 4203175 4526961 MAV_4082 Mycobacterium avium 104 transferase YP_883232.1 4201955 D 243243 CDS YP_883233.1 118466588 4529354 complement(4203185..4204057) 1 NC_008595.1 identified by match to protein family HMM PF00535; transferase 4204057 4529354 MAV_4083 Mycobacterium avium 104 transferase YP_883233.1 4203185 R 243243 CDS YP_883234.1 118463300 4525995 4204047..4205132 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; UDP-glucuronic acid decarboxylase 1 4205132 4525995 MAV_4084 Mycobacterium avium 104 UDP-glucuronic acid decarboxylase 1 YP_883234.1 4204047 D 243243 CDS YP_883235.1 118462532 4527675 4205144..4206784 1 NC_008595.1 identified by match to protein family HMM PF02543; transferase 4206784 4527675 MAV_4085 Mycobacterium avium 104 transferase YP_883235.1 4205144 D 243243 CDS YP_883236.1 118463883 4530560 4206781..4208271 1 NC_008595.1 identified by match to protein family HMM PF00535; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662; transferase 4208271 4530560 MAV_4086 Mycobacterium avium 104 transferase YP_883236.1 4206781 D 243243 CDS YP_883237.1 118463590 4529775 4208280..4209299 1 NC_008595.1 identified by match to protein family HMM PF01075; transferase 4209299 4529775 MAV_4087 Mycobacterium avium 104 transferase YP_883237.1 4208280 D 243243 CDS YP_883238.1 118465594 4527142 4209296..4209865 1 NC_008595.1 identified by match to protein family HMM TIGR00441; phosphoheptose isomerase 4209865 gmhA 4527142 gmhA Mycobacterium avium 104 phosphoheptose isomerase YP_883238.1 4209296 D 243243 CDS YP_883239.1 118462844 4526026 4211285..4211980 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 4211980 4526026 MAV_4090 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_883239.1 4211285 D 243243 CDS YP_883240.1 118463423 4530060 4211971..4212936 1 NC_008595.1 identified by match to protein family HMM PF01075; transferase 4212936 4530060 MAV_4091 Mycobacterium avium 104 transferase YP_883240.1 4211971 D 243243 CDS YP_883241.1 118466706 4529713 4212933..4214237 1 NC_008595.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 4214237 4529713 MAV_4092 Mycobacterium avium 104 UDP-glucose 6-dehydrogenase YP_883241.1 4212933 D 243243 CDS YP_883242.1 118465032 4525811 4214464..4216257 1 NC_008595.1 catalyzes the formation of acetate from pyruvate; thiamine pyrophosphate protein 4216257 4525811 MAV_4093 Mycobacterium avium 104 thiamine pyrophosphate protein YP_883242.1 4214464 D 243243 CDS YP_883243.1 118463844 4529943 complement(4216268..4216933) 1 NC_008595.1 identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758; uracil DNA glycosylase 4216933 4529943 MAV_4094 Mycobacterium avium 104 uracil DNA glycosylase YP_883243.1 4216268 R 243243 CDS YP_883244.1 118464312 4526642 complement(4216998..4217558) 1 NC_008595.1 identified by match to protein family HMM PF01814; hemerythrin HHE cation binding domain-containing protein 4217558 4526642 MAV_4095 Mycobacterium avium 104 hemerythrin HHE cation binding domain-containing protein YP_883244.1 4216998 R 243243 CDS YP_883245.1 118462292 4525637 4217725..4218771 1 NC_008595.1 hypothetical protein 4218771 4525637 MAV_4096 Mycobacterium avium 104 hypothetical protein YP_883245.1 4217725 D 243243 CDS YP_883246.1 118466697 4530439 4218854..4219855 1 NC_008595.1 PknJ protein 4219855 4530439 MAV_4097 Mycobacterium avium 104 PknJ protein YP_883246.1 4218854 D 243243 CDS YP_883247.1 118466374 4529936 4219888..4220862 1 NC_008595.1 identified by match to protein family HMM PF00248; aldo/keto reductase 4220862 4529936 MAV_4098 Mycobacterium avium 104 aldo/keto reductase YP_883247.1 4219888 D 243243 CDS YP_883248.1 118465567 4526753 complement(4220881..4221648) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 4221648 4526753 MAV_4099 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_883248.1 4220881 R 243243 CDS YP_883249.1 118465029 4530078 complement(4221753..4223903) 1 NC_008595.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; glycogen debranching enzyme GlgX 4223903 glgX 4530078 glgX Mycobacterium avium 104 glycogen debranching enzyme GlgX YP_883249.1 4221753 R 243243 CDS YP_883250.1 118466826 4527391 complement(4223997..4225178) 1 NC_008595.1 identified by match to protein family HMM PF00107; S-(hydroxymethyl)glutathione dehydrogenase 4225178 4527391 MAV_4101 Mycobacterium avium 104 S-(hydroxymethyl)glutathione dehydrogenase YP_883250.1 4223997 R 243243 CDS YP_883251.1 118466121 4529754 complement(4225346..4226053) 1 NC_008595.1 identified by match to protein family HMM PF03861; ANTAR domain-containing protein 4226053 4529754 MAV_4102 Mycobacterium avium 104 ANTAR domain-containing protein YP_883251.1 4225346 R 243243 CDS YP_883252.1 118462340 4525685 4226395..4227687 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; dehydrogenase 4227687 4525685 MAV_4103 Mycobacterium avium 104 dehydrogenase YP_883252.1 4226395 D 243243 CDS YP_883253.1 118463062 4528342 complement(4227700..4228236) 1 NC_008595.1 identified by match to protein family HMM PF07098; hypothetical protein 4228236 4528342 MAV_4104 Mycobacterium avium 104 hypothetical protein YP_883253.1 4227700 R 243243 CDS YP_883254.1 118466427 4530171 complement(4228311..4228673) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 4228673 4530171 MAV_4105 Mycobacterium avium 104 MerR family transcriptional regulator YP_883254.1 4228311 R 243243 CDS YP_883255.1 118467136 4527149 4228825..4229268 1 NC_008595.1 identified by match to protein family HMM PF00011; Hsp20/alpha crystallin family protein 4229268 4527149 MAV_4106 Mycobacterium avium 104 Hsp20/alpha crystallin family protein YP_883255.1 4228825 D 243243 CDS YP_883256.1 118467155 4527586 4229394..4230077 1 NC_008595.1 identified by match to protein family HMM PF03861; ANTAR domain-containing protein 4230077 4527586 MAV_4107 Mycobacterium avium 104 ANTAR domain-containing protein YP_883256.1 4229394 D 243243 CDS YP_883257.1 118467162 4527593 complement(4230105..4231760) 1 NC_008595.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730; GAF family protein 4231760 4527593 MAV_4108 Mycobacterium avium 104 GAF family protein YP_883257.1 4230105 R 243243 CDS YP_883258.1 118466851 4529803 complement(4231757..4232425) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; DevR family transcriptional regulator 4232425 4529803 MAV_4109 Mycobacterium avium 104 DevR family transcriptional regulator YP_883258.1 4231757 R 243243 CDS YP_883259.1 118466288 4529534 4232639..4233055 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 4233055 4529534 MAV_4110 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_883259.1 4232639 D 243243 CDS YP_883260.1 118463329 4529199 complement(4233056..4234030) 1 NC_008595.1 hypothetical protein 4234030 4529199 MAV_4111 Mycobacterium avium 104 hypothetical protein YP_883260.1 4233056 R 243243 CDS YP_883261.1 118462329 4525674 4234172..4235332 1 NC_008595.1 identified by match to protein family HMM PF02518; hypothetical protein 4235332 4525674 MAV_4112 Mycobacterium avium 104 hypothetical protein YP_883261.1 4234172 D 243243 CDS YP_883262.1 118465644 4526169 4235322..4235987 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; response regulator receiver domain-containing protein 4235987 4526169 MAV_4114 Mycobacterium avium 104 response regulator receiver domain-containing protein YP_883262.1 4235322 D 243243 CDS YP_883263.1 118465886 4527920 complement(4235951..4237273) 1 NC_008595.1 hypothetical protein 4237273 4527920 MAV_4113 Mycobacterium avium 104 hypothetical protein YP_883263.1 4235951 R 243243 CDS YP_883264.1 118467219 4529600 complement(4237406..4237696) 1 NC_008595.1 identified by match to protein family HMM PF05360; hypothetical protein 4237696 4529600 MAV_4115 Mycobacterium avium 104 hypothetical protein YP_883264.1 4237406 R 243243 CDS YP_883265.1 118466645 4528083 complement(4237742..4239025) 1 NC_008595.1 hypothetical protein 4239025 4528083 MAV_4116 Mycobacterium avium 104 hypothetical protein YP_883265.1 4237742 R 243243 CDS YP_883266.1 118466186 4526217 4239119..4240174 1 NC_008595.1 hypothetical protein 4240174 4526217 MAV_4117 Mycobacterium avium 104 hypothetical protein YP_883266.1 4239119 D 243243 CDS YP_883267.1 118464177 4526487 complement(4240222..4241400) 1 NC_008595.1 identified by match to protein family HMM PF00999; transporter, monovalent cation:proton antiporter-2 (CPA2) family protein 4241400 4526487 MAV_4118 Mycobacterium avium 104 transporter, monovalent cation:proton antiporter-2 (CPA2) family protein YP_883267.1 4240222 R 243243 CDS YP_883268.1 118465441 4527310 complement(4241448..4242530) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase 4242530 4527310 MAV_4119 Mycobacterium avium 104 oxidoreductase YP_883268.1 4241448 R 243243 CDS YP_883269.1 118465995 4526137 complement(4242533..4243462) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4243462 4526137 MAV_4120 Mycobacterium avium 104 alpha/beta hydrolase YP_883269.1 4242533 R 243243 CDS YP_883270.1 118466541 4527009 complement(4243465..4244373) 1 NC_008595.1 FF domain-containing protein 4244373 4527009 MAV_4121 Mycobacterium avium 104 FF domain-containing protein YP_883270.1 4243465 R 243243 CDS YP_883271.1 118467110 4526372 complement(4244404..4247655) 1 NC_008595.1 identified by match to protein family HMM PF00501; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01746; AMP-binding enzyme 4247655 4526372 MAV_4122 Mycobacterium avium 104 AMP-binding enzyme YP_883271.1 4244404 R 243243 CDS YP_883272.1 118463989 4530348 complement(4248128..4249159) 1 NC_008595.1 hypothetical protein 4249159 4530348 MAV_4123 Mycobacterium avium 104 hypothetical protein YP_883272.1 4248128 R 243243 CDS YP_883273.1 118464746 4527642 4249346..4251256 1 NC_008595.1 identified by match to protein family HMM PF00106; dehydrogenase 4251256 4527642 MAV_4124 Mycobacterium avium 104 dehydrogenase YP_883273.1 4249346 D 243243 CDS YP_883274.1 118464153 4526462 complement(4251261..4252577) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4252577 4526462 MAV_4125 Mycobacterium avium 104 virulence factor Mce YP_883274.1 4251261 R 243243 CDS YP_883275.1 118464886 4529615 complement(4252809..4254101) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4254101 4529615 MAV_4126 Mycobacterium avium 104 virulence factor Mce YP_883275.1 4252809 R 243243 CDS YP_883276.1 118465922 4528481 4254363..4255310 1 NC_008595.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 4255310 4528481 MAV_4127 Mycobacterium avium 104 diguanylate cyclase YP_883276.1 4254363 D 243243 CDS YP_883277.1 118466578 4527368 4255362..4255898 1 NC_008595.1 hypothetical protein 4255898 4527368 MAV_4128 Mycobacterium avium 104 hypothetical protein YP_883277.1 4255362 D 243243 CDS YP_883278.1 118462968 4526336 4255922..4256410 1 NC_008595.1 identified by similarity to SP:P06610; match to protein family HMM PF00255; glutathione peroxidase 4256410 4526336 MAV_4129 Mycobacterium avium 104 glutathione peroxidase YP_883278.1 4255922 D 243243 CDS YP_883279.1 118467072 4526450 complement(4256435..4257211) 1 NC_008595.1 immunogenic protein MPT64 4257211 4526450 MAV_4130 Mycobacterium avium 104 immunogenic protein MPT64 YP_883279.1 4256435 R 243243 CDS YP_883280.1 118463020 4526313 complement(4257431..4258702) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 4258702 4526313 MAV_4131 Mycobacterium avium 104 transposase, Mutator family protein YP_883280.1 4257431 R 243243 CDS YP_883281.1 118462482 4530678 4258690..4259871 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 4259871 4530678 MAV_4132 Mycobacterium avium 104 transposase, Mutator family protein YP_883281.1 4258690 D 243243 CDS YP_883282.1 118465623 4528739 complement(4259910..4260128) 1 NC_008595.1 transposase 4260128 4528739 MAV_4133 Mycobacterium avium 104 transposase YP_883282.1 4259910 R 243243 CDS YP_883283.1 118465064 4527040 4260374..4260925 1 NC_008595.1 gp62 protein 4260925 4527040 MAV_4134 Mycobacterium avium 104 gp62 protein YP_883283.1 4260374 D 243243 CDS YP_883284.1 118466828 4527393 complement(4260943..4261653) 1 NC_008595.1 hypothetical protein 4261653 4527393 MAV_4135 Mycobacterium avium 104 hypothetical protein YP_883284.1 4260943 R 243243 CDS YP_883285.1 118466197 4530187 complement(4262181..4265162) 1 NC_008595.1 identified by match to protein family HMM PF03699; hypothetical protein 4265162 4530187 MAV_4137 Mycobacterium avium 104 hypothetical protein YP_883285.1 4262181 R 243243 CDS YP_883286.1 118463477 4525530 complement(4265231..4266253) 1 NC_008595.1 PDZ domain-containing protein 4266253 4525530 MAV_4138 Mycobacterium avium 104 PDZ domain-containing protein YP_883286.1 4265231 R 243243 CDS YP_883287.1 118462810 4529030 4266375..4267739 1 NC_008595.1 hypothetical protein 4267739 4529030 MAV_4139 Mycobacterium avium 104 hypothetical protein YP_883287.1 4266375 D 243243 CDS YP_883288.1 118463035 4528876 4267895..4268764 1 NC_008595.1 hypothetical protein 4268764 4528876 MAV_4140 Mycobacterium avium 104 hypothetical protein YP_883288.1 4267895 D 243243 CDS YP_883289.1 118467166 4527598 4268876..4270204 1 NC_008595.1 identified by match to protein family HMM PF03109; ABC transporter 4270204 4527598 MAV_4141 Mycobacterium avium 104 ABC transporter YP_883289.1 4268876 D 243243 CDS YP_883290.1 118466451 4527124 complement(4270216..4270488) 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB 4270488 4527124 MAV_4142 Mycobacterium avium 104 transcription factor WhiB YP_883290.1 4270216 R 243243 CDS YP_883291.1 118464110 4526281 complement(4270924..4273155) 1 NC_008595.1 identified by match to protein family HMM PF00570; match to protein family HMM PF00580; ATP-dependent DNA helicase 4273155 4526281 MAV_4143 Mycobacterium avium 104 ATP-dependent DNA helicase YP_883291.1 4270924 R 243243 CDS YP_883292.1 118465851 4530644 4273223..4273477 1 NC_008595.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02200; hypothetical protein 4273477 4530644 MAV_4144 Mycobacterium avium 104 hypothetical protein YP_883292.1 4273223 D 243243 CDS YP_883293.1 118462346 4525691 complement(4273486..4274418) 1 NC_008595.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4274418 nudC 4525691 nudC Mycobacterium avium 104 NADH pyrophosphatase YP_883293.1 4273486 R 243243 CDS YP_883294.1 118464754 4527650 complement(4274418..4275488) 1 NC_008595.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885; ion channel membrane protein 4275488 4527650 MAV_4146 Mycobacterium avium 104 ion channel membrane protein YP_883294.1 4274418 R 243243 CDS YP_883295.1 118467070 4526448 complement(4275579..4278869) 1 NC_008595.1 identified by match to protein family HMM PF00580; superfamily protein I DNA and RNA helicases 4278869 4526448 MAV_4147 Mycobacterium avium 104 superfamily protein I DNA and RNA helicases YP_883295.1 4275579 R 243243 CDS YP_883296.1 118466579 4527369 complement(4278866..4281994) 1 NC_008595.1 identified by match to protein family HMM PF00580; helicase, UvrD/Rep family protein 4281994 4527369 MAV_4148 Mycobacterium avium 104 helicase, UvrD/Rep family protein YP_883296.1 4278866 R 243243 CDS YP_883297.1 118465354 4526667 4282119..4282319 1 NC_008595.1 hypothetical protein 4282319 4526667 MAV_4149 Mycobacterium avium 104 hypothetical protein YP_883297.1 4282119 D 243243 CDS YP_883298.1 118467185 4530156 4282380..4283165 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4283165 4530156 MAV_4150 Mycobacterium avium 104 alpha/beta hydrolase YP_883298.1 4282380 D 243243 CDS YP_883299.1 118463839 4526058 4283167..4283469 1 NC_008595.1 identified by match to protein family HMM PF01035; 6-O-methylguanine DNA methyltransferase 4283469 4526058 MAV_4152 Mycobacterium avium 104 6-O-methylguanine DNA methyltransferase YP_883299.1 4283167 D 243243 CDS YP_883300.1 118465095 4529986 complement(4283466..4284320) 1 NC_008595.1 identified by match to protein family HMM TIGR02569; hypothetical protein 4284320 4529986 MAV_4151 Mycobacterium avium 104 hypothetical protein YP_883300.1 4283466 R 243243 CDS YP_883301.1 118462493 4530689 complement(4284356..4285552) 1 NC_008595.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ 4285552 4530689 MAV_4153 Mycobacterium avium 104 molybdopterin biosynthesis-like protein MoeZ YP_883301.1 4284356 R 243243 CDS YP_883302.1 118464633 4528968 complement(4285643..4286782) 1 NC_008595.1 hypothetical protein 4286782 4528968 MAV_4154 Mycobacterium avium 104 hypothetical protein YP_883302.1 4285643 R 243243 CDS YP_883303.1 118463482 4525535 4286887..4287573 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4287573 4525535 MAV_4155 Mycobacterium avium 104 TetR family transcriptional regulator YP_883303.1 4286887 D 243243 CDS YP_883304.1 118464598 4530109 complement(4287581..4287844) 1 NC_008595.1 hypothetical protein 4287844 4530109 MAV_4156 Mycobacterium avium 104 hypothetical protein YP_883304.1 4287581 R 243243 CDS YP_883305.1 118464384 4528273 4288063..4288800 1 NC_008595.1 hypothetical protein 4288800 4528273 MAV_4157 Mycobacterium avium 104 hypothetical protein YP_883305.1 4288063 D 243243 CDS YP_883306.1 118463783 4530134 complement(4288822..4289427) 1 NC_008595.1 hypothetical protein 4289427 4530134 MAV_4158 Mycobacterium avium 104 hypothetical protein YP_883306.1 4288822 R 243243 CDS YP_883307.1 118462952 4526320 4291383..4292573 1 NC_008595.1 hypothetical protein 4292573 4526320 MAV_4160 Mycobacterium avium 104 hypothetical protein YP_883307.1 4291383 D 243243 CDS YP_883308.1 118462223 4525560 complement(4292732..4293532) 1 NC_008595.1 identified by match to protein family HMM PF01656; cobyrinic acid a,c-diamide synthase 4293532 4525560 MAV_4161 Mycobacterium avium 104 cobyrinic acid a,c-diamide synthase YP_883308.1 4292732 R 243243 CDS YP_883309.1 118466548 4527016 4293645..4294229 1 NC_008595.1 forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily; acid phosphatase 4294229 4527016 MAV_4162 Mycobacterium avium 104 acid phosphatase YP_883309.1 4293645 D 243243 CDS YP_883310.1 118465877 4527519 4294226..4295320 1 NC_008595.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase DhbC 4295320 4527519 MAV_4163 Mycobacterium avium 104 isochorismate synthase DhbC YP_883310.1 4294226 D 243243 CDS YP_883311.1 118463461 4529703 4295317..4295799 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase 4295799 4529703 MAV_4165 Mycobacterium avium 104 acetyltransferase YP_883311.1 4295317 D 243243 CDS YP_883312.1 118464623 4526780 complement(4295751..4296182) 1 NC_008595.1 hypothetical protein 4296182 4526780 MAV_4164 Mycobacterium avium 104 hypothetical protein YP_883312.1 4295751 R 243243 CDS YP_883313.1 118462768 4527265 4296385..4297350 1 NC_008595.1 identified by match to protein family HMM PF00781; diacylglycerol kinase catalytic subunit 4297350 4527265 MAV_4166 Mycobacterium avium 104 diacylglycerol kinase catalytic subunit YP_883313.1 4296385 D 243243 CDS YP_883314.1 118462344 4525689 4297632..4297886 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB 4297886 4525689 MAV_4167 Mycobacterium avium 104 transcription factor WhiB YP_883314.1 4297632 D 243243 CDS YP_883315.1 118466753 4526354 complement(4297956..4299455) 1 NC_008595.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07568; sensor histidine kinase 4299455 4526354 MAV_4168 Mycobacterium avium 104 sensor histidine kinase YP_883315.1 4297956 R 243243 CDS YP_883316.1 118467048 4526504 complement(4299484..4299705) 1 NC_008595.1 identified by match to protein family HMM PF00364; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4299705 4526504 MAV_4169 Mycobacterium avium 104 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_883316.1 4299484 R 243243 CDS YP_883317.1 118465818 4525921 complement(4300367..4301173) 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 4301173 4525921 MAV_4171 Mycobacterium avium 104 RNA polymerase sigma factor RpoE YP_883317.1 4300367 R 243243 CDS YP_883318.1 118465274 4527295 4301392..4302240 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 4302240 4527295 MAV_4172 Mycobacterium avium 104 short chain dehydrogenase YP_883318.1 4301392 D 243243 CDS YP_883319.1 118464371 4530514 complement(4302262..4303260) 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 4303260 4530514 MAV_4173 Mycobacterium avium 104 zinc-binding dehydrogenase YP_883319.1 4302262 R 243243 CDS YP_883320.1 118462224 4525561 complement(4303269..4304453) 1 NC_008595.1 hypothetical protein 4304453 4525561 MAV_4174 Mycobacterium avium 104 hypothetical protein YP_883320.1 4303269 R 243243 CDS YP_883321.1 118462815 4529035 complement(4304458..4305207) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 4305207 4529035 MAV_4175 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_883321.1 4304458 R 243243 CDS YP_883322.1 118463369 4528947 complement(4305204..4306469) 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 4306469 4528947 MAV_4176 Mycobacterium avium 104 metallo-beta-lactamase YP_883322.1 4305204 R 243243 CDS YP_883323.1 118466830 4527396 4306554..4307324 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain type dehydrogenase/reductase y4lA 4307324 4527396 MAV_4177 Mycobacterium avium 104 short chain type dehydrogenase/reductase y4lA YP_883323.1 4306554 D 243243 CDS YP_883324.1 118462270 4526415 4307403..4307951 1 NC_008595.1 hypothetical protein 4307951 4526415 MAV_4178 Mycobacterium avium 104 hypothetical protein YP_883324.1 4307403 D 243243 CDS YP_883325.1 118465495 4526791 4308031..4308279 1 NC_008595.1 hypothetical protein 4308279 4526791 MAV_4179 Mycobacterium avium 104 hypothetical protein YP_883325.1 4308031 D 243243 CDS YP_883326.1 118464750 4527646 4308481..4309869 1 NC_008595.1 identified by match to protein family HMM PF02720; hypothetical protein 4309869 4527646 MAV_4180 Mycobacterium avium 104 hypothetical protein YP_883326.1 4308481 D 243243 CDS YP_883327.1 118465154 4529244 complement(4309882..4310646) 1 NC_008595.1 identified by match to protein family HMM PF02586; hypothetical protein 4310646 4529244 MAV_4181 Mycobacterium avium 104 hypothetical protein YP_883327.1 4309882 R 243243 CDS YP_883328.2 229220810 4526820 4310793..4312100 1 NC_008595.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 4312100 aroA 4526820 aroA Mycobacterium avium 104 3-phosphoshikimate 1-carboxyvinyltransferase YP_883328.2 4310793 D 243243 CDS YP_883329.1 118466672 4526622 4312097..4313092 1 NC_008595.1 identified by match to protein family HMM PF03193; GTPase EngC 4313092 4526622 MAV_4184 Mycobacterium avium 104 GTPase EngC YP_883329.1 4312097 D 243243 CDS YP_883330.1 118465834 4525506 complement(4313076..4313552) 1 NC_008595.1 identified by match to protein family HMM PF01638; transcriptional regulator 4313552 4525506 MAV_4183 Mycobacterium avium 104 transcriptional regulator YP_883330.1 4313076 R 243243 CDS YP_883331.1 118467146 4527160 4313647..4314822 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; FadA6_4 4314822 4527160 MAV_4185 Mycobacterium avium 104 FadA6_4 YP_883331.1 4313647 D 243243 CDS YP_883332.1 118465158 4529248 4314827..4315351 1 NC_008595.1 hypothetical protein 4315351 4529248 MAV_4187 Mycobacterium avium 104 hypothetical protein YP_883332.1 4314827 D 243243 CDS YP_883333.1 118466340 4528771 complement(4315709..4316851) 1 NC_008595.1 hypothetical protein 4316851 4528771 MAV_4188 Mycobacterium avium 104 hypothetical protein YP_883333.1 4315709 R 243243 CDS YP_883334.1 118464328 4529833 4316970..4317596 1 NC_008595.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02796; TetR family transcriptional regulator 4317596 4529833 MAV_4189 Mycobacterium avium 104 TetR family transcriptional regulator YP_883334.1 4316970 D 243243 CDS YP_883335.1 118464915 4530750 4317727..4318251 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4318251 4530750 MAV_4190 Mycobacterium avium 104 TetR family transcriptional regulator YP_883335.1 4317727 D 243243 CDS YP_883336.1 118462887 4527494 4318248..4319072 1 NC_008595.1 hypothetical protein 4319072 4527494 MAV_4191 Mycobacterium avium 104 hypothetical protein YP_883336.1 4318248 D 243243 CDS YP_883337.1 118465159 4529249 complement(4319214..4320497) 1 NC_008595.1 identified by match to protein family HMM PF00487; Fatty acid desaturase 4320497 4529249 MAV_4192 Mycobacterium avium 104 Fatty acid desaturase YP_883337.1 4319214 R 243243 CDS YP_883338.1 118463288 4530536 complement(4320597..4321751) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; 2Fe-2S iron-sulfur cluster binding domain-containing protein 4321751 4530536 MAV_4193 Mycobacterium avium 104 2Fe-2S iron-sulfur cluster binding domain-containing protein YP_883338.1 4320597 R 243243 CDS YP_883339.1 118466797 4529043 complement(4321861..4322373) 1 NC_008595.1 hypothetical protein 4322373 4529043 MAV_4194 Mycobacterium avium 104 hypothetical protein YP_883339.1 4321861 R 243243 CDS YP_883340.1 118466404 4526247 complement(4322376..4323233) 1 NC_008595.1 identified by match to protein family HMM PF03976; polyphosphate kinase 2 4323233 4526247 MAV_4195 Mycobacterium avium 104 polyphosphate kinase 2 YP_883340.1 4322376 R 243243 CDS YP_883341.1 118467116 4526142 complement(4323285..4324706) 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 4324706 4526142 MAV_4196 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_883341.1 4323285 R 243243 CDS YP_883342.1 118462376 4529189 4324918..4325478 1 NC_008595.1 hypothetical protein 4325478 4529189 MAV_4197 Mycobacterium avium 104 hypothetical protein YP_883342.1 4324918 D 243243 CDS YP_883343.1 118463113 4527175 complement(4325492..4326640) 1 NC_008595.1 identified by match to protein family HMM PF00999; transporter, monovalent cation:proton antiporter-2 (CPA2) family protein 4326640 4527175 MAV_4198 Mycobacterium avium 104 transporter, monovalent cation:proton antiporter-2 (CPA2) family protein YP_883343.1 4325492 R 243243 CDS YP_883344.1 118465661 4526733 complement(4326645..4327127) 1 NC_008595.1 identified by match to protein family HMM PF02080; TrkA domain-containing protein 4327127 4526733 MAV_4199 Mycobacterium avium 104 TrkA domain-containing protein YP_883344.1 4326645 R 243243 CDS YP_883345.1 118465110 4530462 complement(4327169..4327969) 1 NC_008595.1 hypothetical protein 4327969 4530462 MAV_4200 Mycobacterium avium 104 hypothetical protein YP_883345.1 4327169 R 243243 CDS YP_883346.1 118464557 4530776 complement(4327982..4329553) 1 NC_008595.1 identified by match to protein family HMM PF00196; match to protein family HMM PF01966; LuxR family transcriptional regulator 4329553 4530776 MAV_4201 Mycobacterium avium 104 LuxR family transcriptional regulator YP_883346.1 4327982 R 243243 CDS YP_883347.1 118464264 4528219 complement(4333598..4334278) 1 NC_008595.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; S30AE family protein 4334278 4528219 MAV_4204 Mycobacterium avium 104 S30AE family protein YP_883347.1 4333598 R 243243 CDS YP_883348.1 118465353 4526666 complement(4334386..4334577) 1 NC_008595.1 hypothetical protein 4334577 4526666 MAV_4205 Mycobacterium avium 104 hypothetical protein YP_883348.1 4334386 R 243243 CDS YP_883349.1 118464151 4526460 complement(4334574..4335215) 1 NC_008595.1 hypothetical protein 4335215 4526460 MAV_4206 Mycobacterium avium 104 hypothetical protein YP_883349.1 4334574 R 243243 CDS YP_883350.1 118464672 4528367 complement(4337040..4338671) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 4338671 4528367 MAV_4208 Mycobacterium avium 104 sensor histidine kinase YP_883350.1 4337040 R 243243 CDS YP_883351.1 118464131 4528832 complement(4338796..4339482) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator MtrA 4339482 4528832 MAV_4209 Mycobacterium avium 104 DNA-binding response regulator MtrA YP_883351.1 4338796 R 243243 CDS YP_883352.1 118463240 4525776 complement(4339563..4340195) 1 NC_008595.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 4340195 4525776 MAV_4210 Mycobacterium avium 104 thymidylate kinase YP_883352.1 4339563 R 243243 CDS YP_883353.1 118462675 4530602 complement(4340282..4341772) 1 NC_008595.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 4341772 ahcY 4530602 ahcY Mycobacterium avium 104 S-adenosyl-L-homocysteine hydrolase YP_883353.1 4340282 R 243243 CDS YP_883354.1 118466264 4526883 complement(4341881..4342486) 1 NC_008595.1 identified by match to protein family HMM PF00440; transcriptional regulator 4342486 4526883 MAV_4212 Mycobacterium avium 104 transcriptional regulator YP_883354.1 4341881 R 243243 CDS YP_883355.1 118464460 4527053 complement(4342529..4342711) 1 NC_008595.1 identified by match to protein family HMM PF00301; rubredoxin 4342711 4527053 MAV_4213 Mycobacterium avium 104 rubredoxin YP_883355.1 4342529 R 243243 CDS YP_883356.1 118464421 4530242 complement(4342716..4342889) 1 NC_008595.1 identified by match to protein family HMM PF00301; rubredoxin 4342889 4530242 MAV_4214 Mycobacterium avium 104 rubredoxin YP_883356.1 4342716 R 243243 CDS YP_883357.1 118465756 4530448 complement(4342886..4344133) 1 NC_008595.1 identified by match to protein family HMM PF00487; alkane-1-monooxygenase 4344133 4530448 MAV_4215 Mycobacterium avium 104 alkane-1-monooxygenase YP_883357.1 4342886 R 243243 CDS YP_883358.1 118465164 4529254 complement(4344255..4345772) 1 NC_008595.1 identified by match to protein family HMM PF00324; cationic amino acid transporter 4345772 4529254 MAV_4216 Mycobacterium avium 104 cationic amino acid transporter YP_883358.1 4344255 R 243243 CDS YP_883359.1 118466682 4530424 4345836..4347245 1 NC_008595.1 hypothetical protein 4347245 4530424 MAV_4218 Mycobacterium avium 104 hypothetical protein YP_883359.1 4345836 D 243243 CDS YP_883360.1 118467227 4529784 complement(4347223..4348449) 1 NC_008595.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase, class I 4348449 manA 4529784 manA Mycobacterium avium 104 mannose-6-phosphate isomerase, class I YP_883360.1 4347223 R 243243 CDS YP_883361.1 118462855 4526037 complement(4348458..4349558) 1 NC_008595.1 hypothetical protein 4349558 4526037 MAV_4219 Mycobacterium avium 104 hypothetical protein YP_883361.1 4348458 R 243243 CDS YP_883362.1 118465957 4527953 complement(4351082..4351480) 1 NC_008595.1 hypothetical protein 4351480 4527953 MAV_4221 Mycobacterium avium 104 hypothetical protein YP_883362.1 4351082 R 243243 CDS YP_883363.1 118465767 4530460 4351544..4352137 1 NC_008595.1 hypothetical protein 4352137 4530460 MAV_4222 Mycobacterium avium 104 hypothetical protein YP_883363.1 4351544 D 243243 CDS YP_883364.1 118465072 4525889 complement(4352161..4352499) 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB 4352499 4525889 MAV_4223 Mycobacterium avium 104 transcription factor WhiB YP_883364.1 4352161 R 243243 CDS YP_883365.1 118466901 4528415 4352897..4353910 1 NC_008595.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase 4353910 cofD 4528415 cofD Mycobacterium avium 104 LPPG:FO 2-phospho-L-lactate transferase YP_883365.1 4352897 D 243243 CDS YP_883366.1 118462255 4526398 4353907..4355256 1 NC_008595.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase 4355256 4526398 MAV_4225 Mycobacterium avium 104 F420-0--gamma-glutamyl ligase YP_883366.1 4353907 D 243243 CDS YP_883367.1 118462723 4530097 4355267..4356847 1 NC_008595.1 BpmI methyltransferase 4356847 4530097 MAV_4226 Mycobacterium avium 104 BpmI methyltransferase YP_883367.1 4355267 D 243243 CDS YP_883368.1 118464589 4530294 4356844..4357386 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, nudix family protein, putative 4357386 4530294 MAV_4227 Mycobacterium avium 104 hydrolase, nudix family protein, putative YP_883368.1 4356844 D 243243 CDS YP_883369.1 118466619 4526857 4357388..4357480 1 NC_008595.1 hypothetical protein 4357480 4526857 MAV_4229 Mycobacterium avium 104 hypothetical protein YP_883369.1 4357388 D 243243 CDS YP_883370.1 118463850 4529949 complement(4357462..4358538) 1 NC_008595.1 identified by match to protein family HMM PF00132; match to protein family HMM PF00483; nucleotidyl transferase 4358538 4529949 MAV_4228 Mycobacterium avium 104 nucleotidyl transferase YP_883370.1 4357462 R 243243 CDS YP_883371.1 118465540 4530016 complement(4358540..4359415) 1 NC_008595.1 identified by match to protein family HMM PF00535; dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase 4359415 4530016 MAV_4230 Mycobacterium avium 104 dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase YP_883371.1 4358540 R 243243 CDS YP_883372.1 118465938 4528497 complement(4359417..4360325) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 4360325 rfbD 4528497 rfbD Mycobacterium avium 104 dTDP-4-dehydrorhamnose reductase YP_883372.1 4359417 R 243243 CDS YP_883373.1 118466640 4526996 4360463..4361911 1 NC_008595.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; cell envelope-related function transcriptional attenuator 4361911 4526996 MAV_4232 Mycobacterium avium 104 cell envelope-related function transcriptional attenuator YP_883373.1 4360463 D 243243 CDS YP_883374.1 118467172 4530142 4361917..4362630 1 NC_008595.1 identified by match to protein family HMM TIGR03089; hypothetical protein 4362630 4530142 MAV_4233 Mycobacterium avium 104 hypothetical protein YP_883374.1 4361917 D 243243 CDS YP_883375.1 118463473 4525526 4362734..4363015 1 NC_008595.1 hypothetical protein 4363015 4525526 MAV_4234 Mycobacterium avium 104 hypothetical protein YP_883375.1 4362734 D 243243 CDS YP_883376.1 118466589 4529355 4363026..4365164 1 NC_008595.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-translocating P-type ATPase 4365164 cadA 4529355 cadA Mycobacterium avium 104 cadmium-translocating P-type ATPase YP_883376.1 4363026 D 243243 CDS YP_883377.1 118462302 4525647 4365322..4366236 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4366236 4525647 MAV_4236 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883377.1 4365322 D 243243 CDS YP_883378.1 118462866 4527093 4366248..4367468 1 NC_008595.1 identified by match to protein family HMM PF02515; YfdE protein 4367468 4527093 MAV_4237 Mycobacterium avium 104 YfdE protein YP_883378.1 4366248 D 243243 CDS YP_883379.1 118465473 4527226 complement(4367472..4369442) 1 NC_008595.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01436; serine/threonine protein kinase 4369442 4527226 MAV_4238 Mycobacterium avium 104 serine/threonine protein kinase YP_883379.1 4367472 R 243243 CDS YP_883380.1 118463773 4530124 complement(4369494..4370594) 1 NC_008595.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter phosphate-binding protein PstS 4370594 pstS 4530124 pstS Mycobacterium avium 104 phosphate ABC transporter phosphate-binding protein PstS YP_883380.1 4369494 R 243243 CDS YP_883381.1 118467194 4528428 complement(4370729..4371169) 1 NC_008595.1 identified by match to protein family HMM PF00072; two-component system response regulator 4371169 4528428 MAV_4240 Mycobacterium avium 104 two-component system response regulator YP_883381.1 4370729 R 243243 CDS YP_883382.1 118466648 4528086 complement(4371166..4372773) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF05227; two-component sensor protein 4372773 4528086 MAV_4241 Mycobacterium avium 104 two-component sensor protein YP_883382.1 4371166 R 243243 CDS YP_883383.1 118462899 4528162 complement(4372770..4373972) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF07228; response regulator receiver modulated serine phosphatase 4373972 4528162 MAV_4242 Mycobacterium avium 104 response regulator receiver modulated serine phosphatase YP_883383.1 4372770 R 243243 CDS YP_883384.1 118462363 4527991 complement(4374170..4375339) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4375339 4527991 MAV_4243 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883384.1 4374170 R 243243 CDS YP_883385.1 118463777 4530128 complement(4375358..4375879) 1 NC_008595.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 4375879 purE 4530128 purE Mycobacterium avium 104 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_883385.1 4375358 R 243243 CDS YP_883386.1 118462596 4528500 complement(4375876..4377069) 1 NC_008595.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 4377069 purK 4528500 purK Mycobacterium avium 104 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_883386.1 4375876 R 243243 CDS YP_883387.1 118464004 4529266 4377280..4377945 1 NC_008595.1 identified by match to protein family HMM PF04138; hypothetical protein 4377945 4529266 MAV_4247 Mycobacterium avium 104 hypothetical protein YP_883387.1 4377280 D 243243 CDS YP_883388.1 118464801 4526725 complement(4377900..4378418) 1 NC_008595.1 identified by match to protein family HMM PF03703; hypothetical protein 4378418 4526725 MAV_4246 Mycobacterium avium 104 hypothetical protein YP_883388.1 4377900 R 243243 CDS YP_883389.1 118466138 4527904 complement(4378460..4379254) 1 NC_008595.1 identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM TIGR00121; biotin-[acetyl-CoA-carboxylase] ligase 4379254 4527904 MAV_4248 Mycobacterium avium 104 biotin-[acetyl-CoA-carboxylase] ligase YP_883389.1 4378460 R 243243 CDS YP_883390.1 118466044 4528052 complement(4379302..4380855) 1 NC_008595.1 catalyzes transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase 4380855 4528052 MAV_4249 Mycobacterium avium 104 3-ketosteroid-delta-1-dehydrogenase YP_883390.1 4379302 R 243243 CDS YP_883391.1 118463411 4530048 4380895..4382535 1 NC_008595.1 identified by match to protein family HMM PF01039; propionyl-CoA carboxylase beta chain 4382535 4530048 MAV_4250 Mycobacterium avium 104 propionyl-CoA carboxylase beta chain YP_883391.1 4380895 D 243243 CDS YP_883392.1 118462817 4529037 4382532..4382792 1 NC_008595.1 hypothetical protein 4382792 4529037 MAV_4251 Mycobacterium avium 104 hypothetical protein YP_883392.1 4382532 D 243243 CDS YP_883393.1 118466741 4526342 4382801..4383421 1 NC_008595.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 4383421 maf 4526342 maf Mycobacterium avium 104 Maf-like protein YP_883393.1 4382801 D 243243 CDS YP_883394.1 118466173 4526204 4383568..4384464 1 NC_008595.1 identified by match to protein family HMM PF00581; thiosulfate sulfurtransferase 4384464 4526204 MAV_4253 Mycobacterium avium 104 thiosulfate sulfurtransferase YP_883394.1 4383568 D 243243 CDS YP_883395.1 118463968 4527214 4384475..4384897 1 NC_008595.1 identified by match to protein family HMM PF02657; Fe-S metabolism associated domain-containing protein 4384897 sufE 4527214 sufE Mycobacterium avium 104 Fe-S metabolism associated domain-containing protein YP_883395.1 4384475 D 243243 CDS YP_883396.1 118465082 4525899 4385054..4386817 1 NC_008595.1 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786; acetyl-/propionyl-coenzyme A carboxylase alpha chain 4386817 4525899 MAV_4255 Mycobacterium avium 104 acetyl-/propionyl-coenzyme A carboxylase alpha chain YP_883396.1 4385054 D 243243 CDS YP_883397.1 118464650 4528247 4387014..4387436 1 NC_008595.1 identified by match to protein family HMM PF01740; STAS domain-containing protein 4387436 4528247 MAV_4257 Mycobacterium avium 104 STAS domain-containing protein YP_883397.1 4387014 D 243243 CDS YP_883398.1 118464372 4530515 complement(4387407..4388132) 1 NC_008595.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock; RNA polymerase sigma factor SigF 4388132 4530515 MAV_4256 Mycobacterium avium 104 RNA polymerase sigma factor SigF YP_883398.1 4387407 R 243243 CDS YP_883399.1 118466073 4527340 complement(4388192..4388629) 1 NC_008595.1 RsbW protein 4388629 4527340 MAV_4258 Mycobacterium avium 104 RsbW protein YP_883399.1 4388192 R 243243 CDS YP_883400.1 118463077 4527576 4388737..4388886 1 NC_008595.1 hypothetical protein 4388886 4527576 MAV_4259 Mycobacterium avium 104 hypothetical protein YP_883400.1 4388737 D 243243 CDS YP_883401.1 118465996 4526138 complement(4389075..4389386) 1 NC_008595.1 UsfY protein 4389386 4526138 MAV_4260 Mycobacterium avium 104 UsfY protein YP_883401.1 4389075 R 243243 CDS YP_883402.1 118465381 4529672 complement(4389447..4389773) 1 NC_008595.1 hypothetical protein 4389773 4529672 MAV_4261 Mycobacterium avium 104 hypothetical protein YP_883402.1 4389447 R 243243 CDS YP_883403.1 118467077 4526377 complement(4390027..4391367) 1 NC_008595.1 catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate; L-lysine aminotransferase 4391367 4526377 MAV_4262 Mycobacterium avium 104 L-lysine aminotransferase YP_883403.1 4390027 R 243243 CDS YP_883404.1 118466536 4527004 complement(4391419..4391871) 1 NC_008595.1 identified by match to protein family HMM PF01037; leucine-responsive regulatory protein 4391871 4527004 MAV_4263 Mycobacterium avium 104 leucine-responsive regulatory protein YP_883404.1 4391419 R 243243 CDS YP_883405.1 118462503 4528581 4391944..4393161 1 NC_008595.1 identified by match to protein family HMM PF07063; hypothetical protein 4393161 4528581 MAV_4264 Mycobacterium avium 104 hypothetical protein YP_883405.1 4391944 D 243243 CDS YP_883406.1 118467106 4526368 4393158..4394687 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase (NAD) family protein 4394687 4526368 MAV_4265 Mycobacterium avium 104 aldehyde dehydrogenase (NAD) family protein YP_883406.1 4393158 D 243243 CDS YP_883407.1 118463548 4526815 4394734..4395393 1 NC_008595.1 identified by match to protein family HMM PF00440; hypothetical protein 4395393 4526815 MAV_4266 Mycobacterium avium 104 hypothetical protein YP_883407.1 4394734 D 243243 CDS YP_883408.1 118462983 4527411 4395436..4400067 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase 4400067 4527411 MAV_4267 Mycobacterium avium 104 DEAD/DEAH box helicase YP_883408.1 4395436 D 243243 CDS YP_883409.1 118466005 4528449 complement(4400820..4401737) 1 NC_008595.1 LpqC protein 4401737 4528449 MAV_4268 Mycobacterium avium 104 LpqC protein YP_883409.1 4400820 R 243243 CDS YP_883410.1 118466412 4526255 complement(4401742..4401870) 1 NC_008595.1 hypothetical protein 4401870 4526255 MAV_4270 Mycobacterium avium 104 hypothetical protein YP_883410.1 4401742 R 243243 CDS YP_883411.1 118466072 4530042 4401929..4402282 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 4402282 4530042 MAV_4271 Mycobacterium avium 104 hypothetical protein YP_883411.1 4401929 D 243243 CDS YP_883412.1 118467142 4527156 4402368..4402580 1 NC_008595.1 hypothetical protein 4402580 4527156 MAV_4272 Mycobacterium avium 104 hypothetical protein YP_883412.1 4402368 D 243243 CDS YP_883413.1 118466968 4530367 complement(4402656..4403792) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4403792 4530367 MAV_4273 Mycobacterium avium 104 PPE family protein YP_883413.1 4402656 R 243243 CDS YP_883414.1 118462419 4525729 complement(4403902..4405038) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4405038 4525729 MAV_4274 Mycobacterium avium 104 PPE family protein YP_883414.1 4403902 R 243243 CDS YP_883415.1 118463228 4528802 complement(4405271..4405558) 1 NC_008595.1 hypothetical protein 4405558 4528802 MAV_4275 Mycobacterium avium 104 hypothetical protein YP_883415.1 4405271 R 243243 CDS YP_883416.1 118463828 4526046 complement(4405626..4406222) 1 NC_008595.1 diguanylate cyclase/phosphodiesterase 4406222 4526046 MAV_4276 Mycobacterium avium 104 diguanylate cyclase/phosphodiesterase YP_883416.1 4405626 R 243243 CDS YP_883417.1 118464649 4528246 complement(4406262..4407125) 1 NC_008595.1 identified by match to protein family HMM PF00849; RNA pseudouridine synthase 4407125 4528246 MAV_4277 Mycobacterium avium 104 RNA pseudouridine synthase YP_883417.1 4406262 R 243243 CDS YP_883418.1 118465628 4528745 complement(4407131..4408885) 1 NC_008595.1 identified by match to protein family HMM PF01266; glycerol-3-phosphate dehydrogenase 2 4408885 4528745 MAV_4278 Mycobacterium avium 104 glycerol-3-phosphate dehydrogenase 2 YP_883418.1 4407131 R 243243 CDS YP_883419.1 118465954 4527950 4410510..4410977 1 NC_008595.1 L308_f3_97 4410977 4527950 MAV_4280 Mycobacterium avium 104 L308_f3_97 YP_883419.1 4410510 D 243243 CDS YP_883420.1 118463651 4528553 complement(4411000..4412178) 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; amidohydrolase 4412178 4528553 MAV_4281 Mycobacterium avium 104 amidohydrolase YP_883420.1 4411000 R 243243 CDS YP_883421.1 118464076 4528389 complement(4412175..4413377) 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; amidohydrolase 4413377 4528389 MAV_4282 Mycobacterium avium 104 amidohydrolase YP_883421.1 4412175 R 243243 CDS YP_883422.1 118464739 4529426 complement(4413423..4413977) 1 NC_008595.1 identified by match to protein family HMM PF01083; cutinase Cut3 4413977 4529426 MAV_4283 Mycobacterium avium 104 cutinase Cut3 YP_883422.1 4413423 R 243243 CDS YP_883423.1 118462714 4530088 4414295..4415110 1 NC_008595.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 4415110 4530088 MAV_4284 Mycobacterium avium 104 purine nucleoside phosphorylase YP_883423.1 4414295 D 243243 CDS YP_883424.1 118466210 4528889 4415115..4416695 1 NC_008595.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase 4416695 4528889 MAV_4286 Mycobacterium avium 104 phosphoglucomutase/phosphomannomutase YP_883424.1 4415115 D 243243 CDS YP_883425.1 118463212 4527539 complement(4416547..4417458) 1 NC_008595.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 4417458 upp 4527539 upp Mycobacterium avium 104 uracil phosphoribosyltransferase YP_883425.1 4416547 R 243243 CDS YP_883426.1 118466775 4530770 4417485..4418315 1 NC_008595.1 identified by match to protein family HMM PF04185; secreted acid phosphatase 4418315 4530770 MAV_4287 Mycobacterium avium 104 secreted acid phosphatase YP_883426.1 4417485 D 243243 CDS YP_883427.1 118465050 4525829 4418341..4419654 1 NC_008595.1 hypothetical protein 4419654 4525829 MAV_4288 Mycobacterium avium 104 hypothetical protein YP_883427.1 4418341 D 243243 CDS YP_883428.1 118464548 4530418 complement(4420690..4421697) 1 NC_008595.1 identified by match to protein family HMM PF00092; hypothetical protein 4421697 4530418 MAV_4290 Mycobacterium avium 104 hypothetical protein YP_883428.1 4420690 R 243243 CDS YP_883429.1 118464600 4530111 complement(4421803..4423128) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 4423128 4530111 MAV_4291 Mycobacterium avium 104 transposase, Mutator family protein YP_883429.1 4421803 R 243243 CDS YP_883430.1 118465131 4529162 4423302..4424495 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 4424495 4529162 MAV_4292 Mycobacterium avium 104 hypothetical protein YP_883430.1 4423302 D 243243 CDS YP_883431.1 118465481 4527234 4424603..4425064 1 NC_008595.1 hypothetical protein 4425064 4527234 MAV_4293 Mycobacterium avium 104 hypothetical protein YP_883431.1 4424603 D 243243 CDS YP_883432.1 118466331 4528762 complement(4425216..4426316) 1 NC_008595.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 4426316 add 4528762 add Mycobacterium avium 104 adenosine deaminase YP_883432.1 4425216 R 243243 CDS YP_883433.1 118467210 4529591 complement(4426313..4427596) 1 NC_008595.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4427596 deoA 4529591 deoA Mycobacterium avium 104 thymidine phosphorylase YP_883433.1 4426313 R 243243 CDS YP_883434.1 118466769 4530764 complement(4427596..4427997) 1 NC_008595.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 4427997 cdd 4530764 cdd Mycobacterium avium 104 cytidine deaminase YP_883434.1 4427596 R 243243 CDS YP_883435.1 118463187 4527710 4428269..4428607 1 NC_008595.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970; succinate dehydrogenase, cytochrome b556 subunit 4428607 sdhC 4527710 sdhC Mycobacterium avium 104 succinate dehydrogenase, cytochrome b556 subunit YP_883435.1 4428269 D 243243 CDS YP_883436.1 118464043 4529015 4428604..4429074 1 NC_008595.1 succinate dehydrogenase hydrophobic membrane anchor protein SdhD 4429074 4529015 MAV_4298 Mycobacterium avium 104 succinate dehydrogenase hydrophobic membrane anchor protein SdhD YP_883436.1 4428604 D 243243 CDS YP_883437.1 118464067 4529507 4429082..4430836 1 NC_008595.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 4430836 sdhA 4529507 sdhA Mycobacterium avium 104 succinate dehydrogenase flavoprotein subunit YP_883437.1 4429082 D 243243 CDS YP_883438.1 118464778 4529133 4430837..4431640 1 NC_008595.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 4431640 sdhB 4529133 sdhB Mycobacterium avium 104 succinate dehydrogenase iron-sulfur subunit YP_883438.1 4430837 D 243243 CDS YP_883439.1 118462701 4526681 4431827..4432441 1 NC_008595.1 transposase 4432441 4526681 MAV_4302 Mycobacterium avium 104 transposase YP_883439.1 4431827 D 243243 CDS YP_883440.1 118464731 4529418 complement(4432416..4433372) 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigJ 4433372 4529418 MAV_4301 Mycobacterium avium 104 RNA polymerase sigma factor SigJ YP_883440.1 4432416 R 243243 CDS YP_883441.1 118466647 4528085 4433371..4434702 1 NC_008595.1 identified by match to protein family HMM PF00202; hypothetical protein 4434702 4528085 MAV_4304 Mycobacterium avium 104 hypothetical protein YP_883441.1 4433371 D 243243 CDS YP_883442.1 118463282 4530530 complement(4434677..4434928) 1 NC_008595.1 hypothetical protein 4434928 4530530 MAV_4303 Mycobacterium avium 104 hypothetical protein YP_883442.1 4434677 R 243243 CDS YP_883443.1 118466287 4529533 4435143..4436402 1 NC_008595.1 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 4436402 4529533 MAV_4305 Mycobacterium avium 104 D-alanyl-D-alanine carboxypeptidase YP_883443.1 4435143 D 243243 CDS YP_883444.1 118465249 4528467 4436408..4437760 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; transporter, major facilitator superfamily protein 4437760 4528467 MAV_4306 Mycobacterium avium 104 transporter, major facilitator superfamily protein YP_883444.1 4436408 D 243243 CDS YP_883445.1 118464898 4530733 4437751..4438887 1 NC_008595.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 4438887 nagA 4530733 nagA Mycobacterium avium 104 N-acetylglucosamine-6-phosphate deacetylase YP_883445.1 4437751 D 243243 CDS YP_883446.1 118465465 4526233 4438980..4439294 1 NC_008595.1 identified by match to protein family HMM PF00893; multidrug resistance protein, SMR family protein 4439294 4526233 MAV_4309 Mycobacterium avium 104 multidrug resistance protein, SMR family protein YP_883446.1 4438980 D 243243 CDS YP_883447.1 118463682 4528529 complement(4440330..4441361) 1 NC_008595.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 4441361 trpS 4528529 trpS Mycobacterium avium 104 tryptophanyl-tRNA synthetase YP_883447.1 4440330 R 243243 CDS YP_883448.1 118464143 4528845 4441535..4442332 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4442332 4528845 MAV_4312 Mycobacterium avium 104 alpha/beta hydrolase YP_883448.1 4441535 D 243243 CDS YP_883449.1 118464587 4530292 complement(4442325..4443563) 1 NC_008595.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 4443563 4530292 MAV_4311 Mycobacterium avium 104 isocitrate dehydrogenase YP_883449.1 4442325 R 243243 CDS YP_883450.1 118463374 4528952 complement(4443565..4445802) 1 NC_008595.1 identified by match to protein family HMM PF03971; match to protein family HMM TIGR00178; isocitrate dehydrogenase, NADP-dependent 4445802 4528952 MAV_4313 Mycobacterium avium 104 isocitrate dehydrogenase, NADP-dependent YP_883450.1 4443565 R 243243 CDS YP_883451.1 118464432 4530253 complement(4445920..4446153) 1 NC_008595.1 hypothetical protein 4446153 4530253 MAV_4314 Mycobacterium avium 104 hypothetical protein YP_883451.1 4445920 R 243243 CDS YP_883452.1 118462992 4530622 4446271..4447641 1 NC_008595.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 4447641 4530622 MAV_4315 Mycobacterium avium 104 O-acetylhomoserine aminocarboxypropyltransferase YP_883452.1 4446271 D 243243 CDS YP_883453.1 118462858 4526040 4447653..4448831 1 NC_008595.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 4448831 metX 4526040 metX Mycobacterium avium 104 homoserine O-acetyltransferase YP_883453.1 4447653 D 243243 CDS YP_883454.1 118462516 4528594 4448828..4449559 1 NC_008595.1 methyltransferase 4449559 4528594 MAV_4317 Mycobacterium avium 104 methyltransferase YP_883454.1 4448828 D 243243 CDS YP_883455.1 118466425 4530169 4450896..4452173 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 4452173 4530169 MAV_4319 Mycobacterium avium 104 transposase, Mutator family protein YP_883455.1 4450896 D 243243 CDS YP_883456.1 118467042 4526498 4452277..4452414 1 NC_008595.1 hypothetical protein 4452414 4526498 MAV_4320 Mycobacterium avium 104 hypothetical protein YP_883456.1 4452277 D 243243 CDS YP_883457.1 118465192 4530389 4452562..4453065 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 4453065 4530389 MAV_4321 Mycobacterium avium 104 hypothetical protein YP_883457.1 4452562 D 243243 CDS YP_883458.1 118464798 4526722 complement(4453157..4453438) 1 NC_008595.1 hypothetical protein 4453438 4526722 MAV_4322 Mycobacterium avium 104 hypothetical protein YP_883458.1 4453157 R 243243 CDS YP_883459.1 118465010 4526276 complement(4453435..4454280) 1 NC_008595.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 4454280 4526276 MAV_4323 Mycobacterium avium 104 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_883459.1 4453435 R 243243 CDS YP_883460.1 118466821 4527386 4454421..4455638 1 NC_008595.1 identified by match to protein family HMM PF00724; oxidoreductase, FAD/FMN-binding superfamily protein 4455638 4527386 MAV_4324 Mycobacterium avium 104 oxidoreductase, FAD/FMN-binding superfamily protein YP_883460.1 4454421 D 243243 CDS YP_883461.1 118466082 4527350 4455744..4458284 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061; ABC transporter ATP-binding protein 4458284 4527350 MAV_4325 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_883461.1 4455744 D 243243 CDS YP_883462.1 118463443 4528323 4458343..4460781 1 NC_008595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061; ABC transporter ATP-binding protein 4460781 4528323 MAV_4326 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_883462.1 4458343 D 243243 CDS YP_883463.1 118463434 4528313 complement(4460786..4461343) 1 NC_008595.1 identified by match to protein family HMM PF00805; hypothetical protein 4461343 4528313 MAV_4327 Mycobacterium avium 104 hypothetical protein YP_883463.1 4460786 R 243243 CDS YP_883464.1 118462621 4526423 complement(4461340..4461927) 1 NC_008595.1 identified by match to protein family HMM PF03029; ATP/GTP-binding protein 4461927 4526423 MAV_4328 Mycobacterium avium 104 ATP/GTP-binding protein YP_883464.1 4461340 R 243243 CDS YP_883465.1 118464505 4525548 complement(4461908..4462282) 1 NC_008595.1 identified by match to protein family HMM PF05331; hypothetical protein 4462282 4525548 MAV_4329 Mycobacterium avium 104 hypothetical protein YP_883465.1 4461908 R 243243 CDS YP_883466.1 118465715 4527450 complement(4462290..4462712) 1 NC_008595.1 identified by match to protein family HMM PF03259; roadblock/LC7 domain-contain protein 4462712 4527450 MAV_4330 Mycobacterium avium 104 roadblock/LC7 domain-contain protein YP_883466.1 4462290 R 243243 CDS YP_883467.1 118465732 4525694 complement(4462709..4465552) 1 NC_008595.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; hypothetical protein 4465552 4525694 MAV_4331 Mycobacterium avium 104 hypothetical protein YP_883467.1 4462709 R 243243 CDS YP_883468.1 118465002 4526268 complement(4465802..4466407) 1 NC_008595.1 SAM-dependent methyltransferases 4466407 4526268 MAV_4332 Mycobacterium avium 104 SAM-dependent methyltransferases YP_883468.1 4465802 R 243243 CDS YP_883469.1 118466307 4528349 4466425..4466889 1 NC_008595.1 identified by match to protein family HMM PF00588; RNA methyltransferase, TrmH family protein, group 2 4466889 4528349 MAV_4333 Mycobacterium avium 104 RNA methyltransferase, TrmH family protein, group 2 YP_883469.1 4466425 D 243243 CDS YP_883470.1 118462643 4529384 complement(4466960..4467607) 1 NC_008595.1 identified by match to protein family HMM PF00881; nitroreductase 4467607 4529384 MAV_4334 Mycobacterium avium 104 nitroreductase YP_883470.1 4466960 R 243243 CDS YP_883471.1 118464788 4526712 complement(4467727..4471008) 1 NC_008595.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 4471008 dnaE2 4526712 dnaE2 Mycobacterium avium 104 error-prone DNA polymerase YP_883471.1 4467727 R 243243 CDS YP_883472.1 118465613 4527872 4471180..4472505 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 4472505 4527872 MAV_4336 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_883472.1 4471180 D 243243 CDS YP_883473.1 118465057 4527033 4472549..4473724 1 NC_008595.1 identified by match to protein family HMM PF02358; match to protein family HMM TIGR00685; match to protein family HMM TIGR01484; glycosyl hydrolase 4473724 4527033 MAV_4338 Mycobacterium avium 104 glycosyl hydrolase YP_883473.1 4472549 D 243243 CDS YP_883474.1 118466714 4529721 complement(4473721..4474587) 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC family protein 4474587 4529721 MAV_4337 Mycobacterium avium 104 MaoC family protein YP_883474.1 4473721 R 243243 CDS YP_883475.1 118466235 4526581 4474714..4475394 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 4475394 4526581 MAV_4339 Mycobacterium avium 104 phosphoglycerate mutase YP_883475.1 4474714 D 243243 CDS YP_883476.1 118466238 4526584 4475452..4477509 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; short chain dehydrogenase 4477509 4526584 MAV_4340 Mycobacterium avium 104 short chain dehydrogenase YP_883476.1 4475452 D 243243 CDS YP_883477.1 118464540 4530410 4478314..4479354 1 NC_008595.1 identified by match to protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 4479354 4530410 MAV_4342 Mycobacterium avium 104 inosine-uridine preferring nucleoside hydrolase YP_883477.1 4478314 D 243243 CDS YP_883478.1 118462758 4527848 4479517..4480776 1 NC_008595.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4480776 4527848 MAV_4343 Mycobacterium avium 104 3-oxoacyl-(acyl carrier protein) synthase II YP_883478.1 4479517 D 243243 CDS YP_883479.1 118463486 4529065 4480834..4482012 1 NC_008595.1 identified by match to protein family HMM PF01070; lactate 2-monooxygenase 4482012 4529065 MAV_4345 Mycobacterium avium 104 lactate 2-monooxygenase YP_883479.1 4480834 D 243243 CDS YP_883480.1 118463508 4527688 complement(4482003..4483544) 1 NC_008595.1 hypothetical protein 4483544 4527688 MAV_4344 Mycobacterium avium 104 hypothetical protein YP_883480.1 4482003 R 243243 CDS YP_883481.1 118466153 4528775 complement(4483593..4484282) 1 NC_008595.1 hypothetical protein 4484282 4528775 MAV_4346 Mycobacterium avium 104 hypothetical protein YP_883481.1 4483593 R 243243 CDS YP_883482.1 118466861 4529813 4484498..4484653 1 NC_008595.1 Pd2U protein 4484653 4529813 MAV_4347 Mycobacterium avium 104 Pd2U protein YP_883482.1 4484498 D 243243 CDS YP_883483.1 118465034 4525813 complement(4484685..4486214) 1 NC_008595.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 4486214 guaA 4525813 guaA Mycobacterium avium 104 GMP synthase YP_883483.1 4484685 R 243243 CDS YP_883484.1 118464979 4527471 4486439..4488028 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4488028 4527471 MAV_4349 Mycobacterium avium 104 PPE family protein YP_883484.1 4486439 D 243243 CDS YP_883485.1 118465681 4525740 4488071..4488859 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR02009; beta-phosphoglucomutase hydrolase 4488859 4525740 MAV_4350 Mycobacterium avium 104 beta-phosphoglucomutase hydrolase YP_883485.1 4488071 D 243243 CDS YP_883486.1 118467165 4527597 4488856..4491231 1 NC_008595.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; glycoside hydrolase 65, central catalytic 4491231 4527597 MAV_4352 Mycobacterium avium 104 glycoside hydrolase 65, central catalytic YP_883486.1 4488856 D 243243 CDS YP_883487.1 118464489 4528863 complement(4491225..4491746) 1 NC_008595.1 identified by match to protein family HMM PF00440; HTH-type transcriptional regulator 4491746 4528863 MAV_4351 Mycobacterium avium 104 HTH-type transcriptional regulator YP_883487.1 4491225 R 243243 CDS YP_883488.1 118462395 4525939 4491875..4492768 1 NC_008595.1 identified by match to protein family HMM PF02668; alpha-ketoglutarate-dependent taurine dioxygenase 4492768 4525939 MAV_4353 Mycobacterium avium 104 alpha-ketoglutarate-dependent taurine dioxygenase YP_883488.1 4491875 D 243243 CDS YP_883489.1 118463116 4527178 complement(4492771..4494507) 1 NC_008595.1 identified by match to protein family HMM PF00732; match to protein family HMM PF01266; FAD dependent oxidoreductase 4494507 4527178 MAV_4354 Mycobacterium avium 104 FAD dependent oxidoreductase YP_883489.1 4492771 R 243243 CDS YP_883490.1 118462967 4526335 complement(4494659..4495798) 1 NC_008595.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 4495798 4526335 MAV_4355 Mycobacterium avium 104 inosine 5-monophosphate dehydrogenase YP_883490.1 4494659 R 243243 CDS YP_883491.1 118465329 4526525 complement(4495806..4497401) 1 NC_008595.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 4497401 guaB 4526525 guaB Mycobacterium avium 104 inosine 5'-monophosphate dehydrogenase YP_883491.1 4495806 R 243243 CDS YP_883492.1 118464840 4527956 4497563..4497976 1 NC_008595.1 hypothetical protein 4497976 4527956 MAV_4357 Mycobacterium avium 104 hypothetical protein YP_883492.1 4497563 D 243243 CDS YP_883493.1 118465855 4530649 complement(4497978..4498778) 1 NC_008595.1 hypothetical protein 4498778 4530649 MAV_4358 Mycobacterium avium 104 hypothetical protein YP_883493.1 4497978 R 243243 CDS YP_883494.1 118466654 4528093 complement(4498765..4499343) 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase; RNA polymerase sigma factor SigD 4499343 4528093 MAV_4359 Mycobacterium avium 104 RNA polymerase sigma factor SigD YP_883494.1 4498765 R 243243 CDS YP_883495.1 118467003 4529473 complement(4499434..4500264) 1 NC_008595.1 hypothetical protein 4500264 4529473 MAV_4360 Mycobacterium avium 104 hypothetical protein YP_883495.1 4499434 R 243243 CDS YP_883496.1 118462777 4527274 4500716..4500970 1 NC_008595.1 identified by match to protein family HMM PF02467; transcription factor WhiB 4500970 4527274 MAV_4361 Mycobacterium avium 104 transcription factor WhiB YP_883496.1 4500716 D 243243 CDS YP_883497.1 118464546 4530416 4501013..4501777 1 NC_008595.1 identified by similarity to SP:P53635; match to protein family HMM PF00080; superoxide dismutase, Cu-Zn 4501777 sodC 4530416 sodC Mycobacterium avium 104 superoxide dismutase, Cu-Zn YP_883497.1 4501013 D 243243 CDS YP_883498.1 118466140 4527906 4501805..4501927 1 NC_008595.1 hypothetical protein 4501927 4527906 MAV_4363 Mycobacterium avium 104 hypothetical protein YP_883498.1 4501805 D 243243 CDS YP_883499.1 118463961 4527207 complement(4501933..4503087) 1 NC_008595.1 identified by match to protein family HMM PF01494; hypothetical protein 4503087 4527207 MAV_4364 Mycobacterium avium 104 hypothetical protein YP_883499.1 4501933 R 243243 CDS YP_883500.1 118463711 4528061 complement(4503246..4504862) 1 NC_008595.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; chaperonin GroEL 4504862 groEL 4528061 groEL Mycobacterium avium 104 chaperonin GroEL YP_883500.1 4503246 R 243243 CDS YP_883501.1 118465749 4530441 complement(4504951..4505253) 1 NC_008595.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4505253 groES 4530441 groES Mycobacterium avium 104 co-chaperonin GroES YP_883501.1 4504951 R 243243 CDS YP_883502.1 118465394 4525654 complement(4505459..4506484) 1 NC_008595.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 4506484 4525654 MAV_4367 Mycobacterium avium 104 DNA-binding/iron metalloprotein/AP endonuclease YP_883502.1 4505459 R 243243 CDS YP_883503.1 118466713 4529720 complement(4506481..4506951) 1 NC_008595.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 4506951 rimI 4529720 rimI Mycobacterium avium 104 ribosomal-protein-alanine acetyltransferase YP_883503.1 4506481 R 243243 CDS YP_883504.1 118466532 4527000 complement(4506948..4507574) 1 NC_008595.1 identified by match to protein family HMM PF00814; peptidase M22, glycoprotease 4507574 4527000 MAV_4369 Mycobacterium avium 104 peptidase M22, glycoprotease YP_883504.1 4506948 R 243243 CDS YP_883505.1 118463418 4530055 complement(4507571..4508050) 1 NC_008595.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 4508050 4530055 MAV_4370 Mycobacterium avium 104 hypothetical protein YP_883505.1 4507571 R 243243 CDS YP_883506.1 118463034 4528875 complement(4508043..4509092) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4509092 4528875 MAV_4371 Mycobacterium avium 104 alpha/beta hydrolase YP_883506.1 4508043 R 243243 CDS YP_883507.1 118465728 4527463 complement(4509145..4510311) 1 NC_008595.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4510311 alr 4527463 alr Mycobacterium avium 104 alanine racemase YP_883507.1 4509145 R 243243 CDS YP_883508.1 118465357 4529217 complement(4510422..4511801) 1 NC_008595.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase 4511801 4529217 MAV_4373 Mycobacterium avium 104 glutamate decarboxylase YP_883508.1 4510422 R 243243 CDS YP_883509.1 118466850 4526959 complement(4511824..4513245) 1 NC_008595.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; carbohydrate kinase 4513245 4526959 MAV_4374 Mycobacterium avium 104 carbohydrate kinase YP_883509.1 4511824 R 243243 CDS YP_883510.1 118462563 4528622 complement(4513309..4514013) 1 NC_008595.1 hypothetical protein 4514013 4528622 MAV_4375 Mycobacterium avium 104 hypothetical protein YP_883510.1 4513309 R 243243 CDS YP_883511.1 118464448 4525979 complement(4514107..4514994) 1 NC_008595.1 hypothetical protein 4514994 4525979 MAV_4376 Mycobacterium avium 104 hypothetical protein YP_883511.1 4514107 R 243243 CDS YP_883512.1 118464108 4526279 complement(4515109..4516983) 1 NC_008595.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4516983 glmS 4526279 glmS Mycobacterium avium 104 glucosamine--fructose-6-phosphate aminotransferase YP_883512.1 4515109 R 243243 CDS YP_883513.1 118463000 4530630 4516997..4517299 1 NC_008595.1 hypothetical protein 4517299 4530630 MAV_4378 Mycobacterium avium 104 hypothetical protein YP_883513.1 4516997 D 243243 CDS YP_883514.1 118465576 4526762 4517399..4517593 1 NC_008595.1 hypothetical protein 4517593 4526762 MAV_4379 Mycobacterium avium 104 hypothetical protein YP_883514.1 4517399 D 243243 CDS YP_883515.1 118467021 4526533 4517650..4518489 1 NC_008595.1 hypothetical protein 4518489 4526533 MAV_4380 Mycobacterium avium 104 hypothetical protein YP_883515.1 4517650 D 243243 CDS YP_883516.1 118467297 4527255 4518515..4519555 1 NC_008595.1 identified by match to protein family HMM PF00296; oxidoreductase 4519555 4527255 MAV_4381 Mycobacterium avium 104 oxidoreductase YP_883516.1 4518515 D 243243 CDS YP_883517.1 118465307 4526561 complement(4519560..4521026) 1 NC_008595.1 hypothetical protein 4521026 4526561 MAV_4382 Mycobacterium avium 104 hypothetical protein YP_883517.1 4519560 R 243243 CDS YP_883518.1 118463571 4530726 complement(4521030..4521359) 1 NC_008595.1 hypothetical protein 4521359 4530726 MAV_4383 Mycobacterium avium 104 hypothetical protein YP_883518.1 4521030 R 243243 CDS YP_883519.1 118463150 4527788 complement(4521408..4522742) 1 NC_008595.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 4522742 glmM 4527788 glmM Mycobacterium avium 104 phosphoglucosamine mutase YP_883519.1 4521408 R 243243 CDS YP_883520.1 118466344 4530484 complement(4522905..4523405) 1 NC_008595.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 4523405 rpsI 4530484 rpsI Mycobacterium avium 104 30S ribosomal protein S9 YP_883520.1 4522905 R 243243 CDS YP_883521.1 118466515 4527188 complement(4523402..4523845) 1 NC_008595.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 4523845 rplM 4527188 rplM Mycobacterium avium 104 50S ribosomal protein L13 YP_883521.1 4523402 R 243243 CDS YP_883522.1 118467089 4526389 complement(4524068..4524364) 1 NC_008595.1 identified by match to protein family HMM PF06013; hypothetical protein 4524364 4526389 MAV_4387 Mycobacterium avium 104 hypothetical protein YP_883522.1 4524068 R 243243 CDS YP_883523.1 118465412 4529961 complement(4524380..4524679) 1 NC_008595.1 hypothetical protein 4524679 4529961 MAV_4388 Mycobacterium avium 104 hypothetical protein YP_883523.1 4524380 R 243243 CDS YP_883524.1 118465986 4526128 complement(4524745..4525875) 1 NC_008595.1 hypothetical protein 4525875 4526128 MAV_4389 Mycobacterium avium 104 hypothetical protein YP_883524.1 4524745 R 243243 CDS YP_883525.1 118463646 4528548 complement(4525959..4529552) 1 NC_008595.1 identified by match to protein family HMM PF01580; ftsk/SpoIIIE family protein 4529552 4528548 MAV_4390 Mycobacterium avium 104 ftsk/SpoIIIE family protein YP_883525.1 4525959 R 243243 CDS YP_883526.1 118466832 4526941 4529676..4531037 1 NC_008595.1 hypothetical protein 4531037 4526941 MAV_4391 Mycobacterium avium 104 hypothetical protein YP_883526.1 4529676 D 243243 CDS YP_883527.1 118465498 4526794 4531043..4532332 1 NC_008595.1 identified by match to protein family HMM PF00082; peptidase 4532332 4526794 MAV_4393 Mycobacterium avium 104 peptidase YP_883527.1 4531043 D 243243 CDS YP_883528.1 118464971 4528711 complement(4532297..4533670) 1 NC_008595.1 identified by match to protein family HMM PF05108; hypothetical protein 4533670 4528711 MAV_4392 Mycobacterium avium 104 hypothetical protein YP_883528.1 4532297 R 243243 CDS YP_883529.1 118465672 4526744 4533789..4534658 1 NC_008595.1 identified by match to protein family HMM PF01083; serine esterase, cutinase 4534658 4526744 MAV_4394 Mycobacterium avium 104 serine esterase, cutinase YP_883529.1 4533789 D 243243 CDS YP_883530.1 118464654 4528251 4534716..4535336 1 NC_008595.1 identified by match to protein family HMM PF01083; cutinase 4535336 4528251 MAV_4396 Mycobacterium avium 104 cutinase YP_883530.1 4534716 D 243243 CDS YP_883531.1 118462566 4528625 complement(4535333..4536088) 1 NC_008595.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 4536088 truA 4528625 truA Mycobacterium avium 104 tRNA pseudouridine synthase A YP_883531.1 4535333 R 243243 CDS YP_883532.1 118463464 4525517 complement(4536171..4536731) 1 NC_008595.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 4536731 rplQ 4525517 rplQ Mycobacterium avium 104 50S ribosomal protein L17 YP_883532.1 4536171 R 243243 CDS YP_883533.1 118463576 4530731 complement(4536760..4537803) 1 NC_008595.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 4537803 rpoA 4530731 rpoA Mycobacterium avium 104 DNA-directed RNA polymerase subunit alpha YP_883533.1 4536760 R 243243 CDS YP_883534.1 118464319 4529824 complement(4537882..4538487) 1 NC_008595.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 4538487 rpsD 4529824 rpsD Mycobacterium avium 104 30S ribosomal protein S4 YP_883534.1 4537882 R 243243 CDS YP_883535.1 118462594 4530215 complement(4538496..4538912) 1 NC_008595.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 4538912 rpsK 4530215 rpsK Mycobacterium avium 104 30S ribosomal protein S11 YP_883535.1 4538496 R 243243 CDS YP_883536.1 118465138 4529169 complement(4538919..4539251) 1 NC_008595.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 4539251 rpsM 4529169 rpsM Mycobacterium avium 104 30S ribosomal protein S13 YP_883536.1 4538919 R 243243 CDS YP_883537.1 118464195 4529306 complement(4539499..4539612) 1 NC_008595.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 4539612 rpmJ 4529306 rpmJ Mycobacterium avium 104 50S ribosomal protein L36 YP_883537.1 4539499 R 243243 CDS YP_883538.1 118463643 4528545 complement(4539638..4539859) 1 NC_008595.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 4539859 infA 4528545 infA Mycobacterium avium 104 translation initiation factor IF-1 YP_883538.1 4539638 R 243243 CDS YP_883539.1 118462971 4527399 4540114..4540962 1 NC_008595.1 hypothetical protein 4540962 4527399 MAV_4404 Mycobacterium avium 104 hypothetical protein YP_883539.1 4540114 D 243243 CDS YP_883540.1 118463245 4525781 4540979..4541845 1 NC_008595.1 hypothetical protein 4541845 4525781 MAV_4405 Mycobacterium avium 104 hypothetical protein YP_883540.1 4540979 D 243243 CDS YP_883541.1 118466831 4527397 4541873..4542868 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 4542868 rfbB 4527397 rfbB Mycobacterium avium 104 dTDP-glucose 4,6-dehydratase YP_883541.1 4541873 D 243243 CDS YP_883542.1 118467223 4529604 4542870..4543475 1 NC_008595.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase 4543475 rfbC 4529604 rfbC Mycobacterium avium 104 dTDP-4-dehydrorhamnose 3,5-epimerase YP_883542.1 4542870 D 243243 CDS YP_883543.1 118464220 4526900 4543708..4544832 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase 4544832 4526900 MAV_4408 Mycobacterium avium 104 acyltransferase YP_883543.1 4543708 D 243243 CDS YP_883544.1 118463864 4527742 4544932..4546077 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase 4546077 4527742 MAV_4409 Mycobacterium avium 104 acyltransferase YP_883544.1 4544932 D 243243 CDS YP_883545.1 118464447 4525978 4546162..4547250 1 NC_008595.1 identified by match to protein family HMM PF01757; AtfA_1 4547250 4525978 MAV_4410 Mycobacterium avium 104 AtfA_1 YP_883545.1 4546162 D 243243 CDS YP_883546.1 118462350 4527977 4547247..4547486 1 NC_008595.1 hypothetical protein 4547486 4527977 MAV_4411 Mycobacterium avium 104 hypothetical protein YP_883546.1 4547247 D 243243 CDS YP_883547.1 118462271 4529276 complement(4547572..4548492) 1 NC_008595.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR01409; metallophosphoesterase 4548492 4529276 MAV_4412 Mycobacterium avium 104 metallophosphoesterase YP_883547.1 4547572 R 243243 CDS YP_883548.1 118462975 4527403 complement(4548489..4548881) 1 NC_008595.1 identified by match to protein family HMM PF00127; copper binding proteins, plastocyanin/azurin family protein 4548881 4527403 MAV_4413 Mycobacterium avium 104 copper binding proteins, plastocyanin/azurin family protein YP_883548.1 4548489 R 243243 CDS YP_883549.1 118462790 4525758 complement(4548906..4549613) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 4549613 4525758 MAV_4414 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_883549.1 4548906 R 243243 CDS YP_883550.1 118463186 4527709 complement(4549610..4550149) 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase sigma factor, sigma-70 family protein 4550149 4527709 MAV_4415 Mycobacterium avium 104 RNA polymerase sigma factor, sigma-70 family protein YP_883550.1 4549610 R 243243 CDS YP_883551.1 118466375 4529937 complement(4550194..4551618) 1 NC_008595.1 hypothetical protein 4551618 4529937 MAV_4416 Mycobacterium avium 104 hypothetical protein YP_883551.1 4550194 R 243243 CDS YP_883552.1 118464277 4528232 4551729..4553249 1 NC_008595.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722; methylmalonate-semialdehyde dehydrogenase 4553249 mmsA 4528232 mmsA Mycobacterium avium 104 methylmalonate-semialdehyde dehydrogenase YP_883552.1 4551729 D 243243 CDS YP_883553.1 118465062 4527038 4553276..4554436 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase member 8 4554436 4527038 MAV_4418 Mycobacterium avium 104 acyl-CoA dehydrogenase member 8 YP_883553.1 4553276 D 243243 CDS YP_883554.1 118464116 4526287 4554461..4555336 1 NC_008595.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01692; 3-hydroxyisobutyrate dehydrogenase 4555336 mmsB 4526287 mmsB Mycobacterium avium 104 3-hydroxyisobutyrate dehydrogenase YP_883554.1 4554461 D 243243 CDS YP_883555.1 118464137 4528839 complement(4555412..4555918) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 4555918 4528839 MAV_4420 Mycobacterium avium 104 MarR family transcriptional regulator YP_883555.1 4555412 R 243243 CDS YP_883556.1 118467274 4527076 complement(4555927..4556985) 1 NC_008595.1 identified by match to protein family HMM PF00155; histidinol-phosphate aminotransferase 4556985 4527076 MAV_4421 Mycobacterium avium 104 histidinol-phosphate aminotransferase YP_883556.1 4555927 R 243243 CDS YP_883557.1 118462248 4526934 complement(4556979..4558004) 1 NC_008595.1 3-oxoacyl-ACP synthase III 4558004 4526934 MAV_4422 Mycobacterium avium 104 3-oxoacyl-ACP synthase III YP_883557.1 4556979 R 243243 CDS YP_883558.1 118466157 4528779 complement(4558009..4558656) 1 NC_008595.1 hypothetical protein 4558656 4528779 MAV_4423 Mycobacterium avium 104 hypothetical protein YP_883558.1 4558009 R 243243 CDS YP_883559.1 118467022 4526534 complement(4558637..4560388) 1 NC_008595.1 identified by match to protein family HMM PF02775; match to protein family HMM PF02776; acetolactate synthase 4560388 4526534 MAV_4424 Mycobacterium avium 104 acetolactate synthase YP_883559.1 4558637 R 243243 CDS YP_883560.1 118464985 4527477 4560500..4561195 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATPase 4561195 4527477 MAV_4425 Mycobacterium avium 104 ABC transporter ATPase YP_883560.1 4560500 D 243243 CDS YP_883561.1 118463283 4530531 4561237..4563690 1 NC_008595.1 identified by match to protein family HMM PF02687; efflux ABC transporter permease 4563690 4530531 MAV_4427 Mycobacterium avium 104 efflux ABC transporter permease YP_883561.1 4561237 D 243243 CDS YP_883562.1 118465850 4530643 complement(4563677..4564303) 1 NC_008595.1 identified by match to protein family HMM PF01209; methyltransferase, UbiE/COQ5 family protein 4564303 4530643 MAV_4426 Mycobacterium avium 104 methyltransferase, UbiE/COQ5 family protein YP_883562.1 4563677 R 243243 CDS YP_883563.1 118464204 4526884 complement(4564300..4564866) 1 NC_008595.1 hypothetical protein 4564866 4526884 MAV_4428 Mycobacterium avium 104 hypothetical protein YP_883563.1 4564300 R 243243 CDS YP_883564.1 118464459 4527052 complement(4564890..4566131) 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; FAD binding domain-containing protein 4566131 4527052 MAV_4429 Mycobacterium avium 104 FAD binding domain-containing protein YP_883564.1 4564890 R 243243 CDS YP_883565.1 118462268 4526412 complement(4566147..4566866) 1 NC_008595.1 hypothetical protein 4566866 4526412 MAV_4430 Mycobacterium avium 104 hypothetical protein YP_883565.1 4566147 R 243243 CDS YP_883566.1 118466573 4527362 complement(4566900..4567436) 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins; RNA polymerase sigma factor SigL 4567436 4527362 MAV_4431 Mycobacterium avium 104 RNA polymerase sigma factor SigL YP_883566.1 4566900 R 243243 CDS YP_883567.1 118463378 4528956 complement(4567515..4568315) 1 NC_008595.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 4568315 map 4528956 map Mycobacterium avium 104 methionine aminopeptidase YP_883567.1 4567515 R 243243 CDS YP_883568.2 229220808 4528673 complement(4568318..4568863) 1 NC_008595.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 4568863 adk 4528673 adk Mycobacterium avium 104 adenylate kinase YP_883568.2 4568318 R 243243 CDS YP_883569.1 118466392 4526193 complement(4568860..4570221) 1 NC_008595.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 4570221 secY 4526193 secY Mycobacterium avium 104 preprotein translocase subunit SecY YP_883569.1 4568860 R 243243 CDS YP_883570.1 118465667 4526739 4570399..4571310 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4571310 4526739 MAV_4435 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883570.1 4570399 D 243243 CDS YP_883571.1 118464855 4527971 complement(4571314..4571979) 1 NC_008595.1 hypothetical protein 4571979 4527971 MAV_4436 Mycobacterium avium 104 hypothetical protein YP_883571.1 4571314 R 243243 CDS YP_883572.1 118464784 4526708 complement(4572006..4573361) 1 NC_008595.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; carbohydrate kinase, FGGY family protein 4573361 4526708 MAV_4437 Mycobacterium avium 104 carbohydrate kinase, FGGY family protein YP_883572.1 4572006 R 243243 CDS YP_883573.1 118464026 4528822 4573392..4574372 1 NC_008595.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; 2-hydroxyacid dehydrogenase 4574372 4528822 MAV_4438 Mycobacterium avium 104 2-hydroxyacid dehydrogenase YP_883573.1 4573392 D 243243 CDS YP_883574.1 118463286 4530534 4574369..4575022 1 NC_008595.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose-phosphate aldolase 4575022 4530534 MAV_4439 Mycobacterium avium 104 L-fuculose-phosphate aldolase YP_883574.1 4574369 D 243243 CDS YP_883575.1 118462601 4528505 complement(4575049..4576281) 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 4576281 4528505 MAV_4440 Mycobacterium avium 104 zinc-binding dehydrogenase YP_883575.1 4575049 R 243243 CDS YP_883576.1 118466662 4526612 4576438..4577382 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase 4577382 4526612 MAV_4441 Mycobacterium avium 104 methyltransferase YP_883576.1 4576438 D 243243 CDS YP_883577.1 118466154 4528776 4577375..4578295 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4578295 4528776 MAV_4442 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883577.1 4577375 D 243243 CDS YP_883578.1 118464245 4527430 4578307..4579221 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4579221 4527430 MAV_4444 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883578.1 4578307 D 243243 CDS YP_883579.1 118462440 4528303 complement(4579218..4581005) 1 NC_008595.1 identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706; signal peptide peptidase SppA, 67K type 4581005 sppA 4528303 sppA Mycobacterium avium 104 signal peptide peptidase SppA, 67K type YP_883579.1 4579218 R 243243 CDS YP_883580.1 118465752 4530444 4581044..4581970 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 4581970 4530444 MAV_4445 Mycobacterium avium 104 hypothetical protein YP_883580.1 4581044 D 243243 CDS YP_883581.1 118463835 4526054 complement(4581984..4582424) 1 NC_008595.1 late assembly protein; 50S ribosomal protein L15 4582424 rplO 4526054 rplO Mycobacterium avium 104 50S ribosomal protein L15 YP_883581.1 4581984 R 243243 CDS YP_883582.1 118467160 4527591 complement(4582421..4582636) 1 NC_008595.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 4582636 rpmD 4527591 rpmD Mycobacterium avium 104 50S ribosomal protein L30 YP_883582.1 4582421 R 243243 CDS YP_883583.1 118465328 4526524 complement(4582633..4583310) 1 NC_008595.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 4583310 rpsE 4526524 rpsE Mycobacterium avium 104 30S ribosomal protein S5 YP_883583.1 4582633 R 243243 CDS YP_883584.1 118463503 4527683 complement(4583345..4583713) 1 NC_008595.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 4583713 rplR 4527683 rplR Mycobacterium avium 104 50S ribosomal protein L18 YP_883584.1 4583345 R 243243 CDS YP_883585.1 118462903 4528166 complement(4583755..4584294) 1 NC_008595.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 4584294 rplF 4528166 rplF Mycobacterium avium 104 50S ribosomal protein L6 YP_883585.1 4583755 R 243243 CDS YP_883586.1 118466703 4529710 complement(4584305..4584697) 1 NC_008595.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 4584697 rpsH 4529710 rpsH Mycobacterium avium 104 30S ribosomal protein S8 YP_883586.1 4584305 R 243243 CDS YP_883587.1 118463275 4530523 complement(4584724..4584909) 1 NC_008595.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 4584909 rpsN 4530523 rpsN Mycobacterium avium 104 30S ribosomal protein S14 YP_883587.1 4584724 R 243243 CDS YP_883588.1 118464148 4526457 complement(4584914..4585477) 1 NC_008595.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 4585477 rplE 4526457 rplE Mycobacterium avium 104 50S ribosomal protein L5 YP_883588.1 4584914 R 243243 CDS YP_883589.1 118465840 4525512 complement(4585479..4585796) 1 NC_008595.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 4585796 rplX 4525512 rplX Mycobacterium avium 104 50S ribosomal protein L24 YP_883589.1 4585479 R 243243 CDS YP_883590.1 118465569 4526755 complement(4585797..4586165) 1 NC_008595.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 4586165 rplN 4526755 rplN Mycobacterium avium 104 50S ribosomal protein L14 YP_883590.1 4585797 R 243243 CDS YP_883591.1 118467288 4527246 complement(4586417..4587919) 1 NC_008595.1 identified by match to protein family HMM PF01844; match to protein family HMM PF02720; hypothetical protein 4587919 4527246 MAV_4456 Mycobacterium avium 104 hypothetical protein YP_883591.1 4586417 R 243243 CDS YP_883592.1 118466993 4529520 complement(4588007..4588894) 1 NC_008595.1 hypothetical protein 4588894 4529520 MAV_4457 Mycobacterium avium 104 hypothetical protein YP_883592.1 4588007 R 243243 CDS YP_883593.1 118466185 4526216 complement(4589078..4589968) 1 NC_008595.1 identified by match to protein family HMM PF03781; sulfatase-modifying factor 1 4589968 4526216 MAV_4458 Mycobacterium avium 104 sulfatase-modifying factor 1 YP_883593.1 4589078 R 243243 CDS YP_883594.1 118462593 4530214 complement(4589997..4590938) 1 NC_008595.1 hypothetical protein 4590938 4530214 MAV_4459 Mycobacterium avium 104 hypothetical protein YP_883594.1 4589997 R 243243 CDS YP_883595.1 118465662 4526734 4591206..4592333 1 NC_008595.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter phosphate-binding protein PstS 4592333 pstS 4526734 pstS Mycobacterium avium 104 phosphate ABC transporter phosphate-binding protein PstS YP_883595.1 4591206 D 243243 CDS YP_883596.1 118465079 4525896 complement(4592346..4594715) 1 NC_008595.1 identified by match to protein family HMM PF00884; arylsulfatase 4594715 4525896 MAV_4461 Mycobacterium avium 104 arylsulfatase YP_883596.1 4592346 R 243243 CDS YP_883597.1 118464323 4529828 complement(4594806..4595156) 1 NC_008595.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 4595156 rpsQ 4529828 rpsQ Mycobacterium avium 104 30S ribosomal protein S17 YP_883597.1 4594806 R 243243 CDS YP_883598.1 118463930 4528110 complement(4595156..4595389) 1 NC_008595.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 4595389 rpmC 4528110 rpmC Mycobacterium avium 104 50S ribosomal protein L29 YP_883598.1 4595156 R 243243 CDS YP_883599.1 118463172 4529874 complement(4595389..4595805) 1 NC_008595.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 4595805 rplP 4529874 rplP Mycobacterium avium 104 50S ribosomal protein L16 YP_883599.1 4595389 R 243243 CDS YP_883600.1 118465225 4525595 complement(4595809..4596651) 1 NC_008595.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 4596651 rpsC 4525595 rpsC Mycobacterium avium 104 30S ribosomal protein S3 YP_883600.1 4595809 R 243243 CDS YP_883601.1 118467254 4526089 complement(4596651..4597193) 1 NC_008595.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 4597193 rplV 4526089 rplV Mycobacterium avium 104 50S ribosomal protein L22 YP_883601.1 4596651 R 243243 CDS YP_883602.1 118463768 4528012 complement(4597190..4597471) 1 NC_008595.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 4597471 rpsS 4528012 rpsS Mycobacterium avium 104 30S ribosomal protein S19 YP_883602.1 4597190 R 243243 CDS YP_883603.1 118465782 4526917 complement(4597499..4598341) 1 NC_008595.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 4598341 rplB 4526917 rplB Mycobacterium avium 104 50S ribosomal protein L2 YP_883603.1 4597499 R 243243 CDS YP_883604.1 118462258 4526401 complement(4598364..4598666) 1 NC_008595.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 4598666 rplW 4526401 rplW Mycobacterium avium 104 50S ribosomal protein L23 YP_883604.1 4598364 R 243243 CDS YP_883605.1 118466008 4528453 complement(4598666..4599319) 1 NC_008595.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 4599319 rplD 4528453 rplD Mycobacterium avium 104 50S ribosomal protein L4 YP_883605.1 4598666 R 243243 CDS YP_883606.1 118463063 4528343 complement(4599319..4599972) 1 NC_008595.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 4599972 rplC 4528343 rplC Mycobacterium avium 104 50S ribosomal protein L3 YP_883606.1 4599319 R 243243 CDS YP_883607.1 118467320 4530313 complement(4599987..4600292) 1 NC_008595.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 4600292 rpsJ 4530313 rpsJ Mycobacterium avium 104 30S ribosomal protein S10 YP_883607.1 4599987 R 243243 CDS YP_883608.1 118466004 4528448 complement(4600643..4601188) 1 NC_008595.1 hypothetical protein 4601188 4528448 MAV_4473 Mycobacterium avium 104 hypothetical protein YP_883608.1 4600643 R 243243 CDS YP_883609.1 118463833 4526051 complement(4601390..4602829) 1 NC_008595.1 identified by match to protein family HMM PF00732; match to protein family HMM PF01266; match to protein family HMM PF05199; FAD dependent oxidoreductase, putative 4602829 4526051 MAV_4474 Mycobacterium avium 104 FAD dependent oxidoreductase, putative YP_883609.1 4601390 R 243243 CDS YP_883610.1 118466833 4526942 complement(4602839..4604257) 1 NC_008595.1 identified by match to protein family HMM PF00535; membrane sugar transferase 4604257 4526942 MAV_4475 Mycobacterium avium 104 membrane sugar transferase YP_883610.1 4602839 R 243243 CDS YP_883611.1 118465285 4529321 complement(4604254..4604985) 1 NC_008595.1 identified by match to protein family HMM PF02633; creatininase subfamily protein 4604985 4529321 MAV_4476 Mycobacterium avium 104 creatininase subfamily protein YP_883611.1 4604254 R 243243 CDS YP_883612.1 118462266 4526410 complement(4605150..4606334) 1 NC_008595.1 identified by match to protein family HMM PF01070; FMN-dependent dehydrogenase 4606334 4526410 MAV_4477 Mycobacterium avium 104 FMN-dependent dehydrogenase YP_883612.1 4605150 R 243243 CDS YP_883613.1 118462987 4527416 complement(4606337..4607551) 1 NC_008595.1 identified by match to protein family HMM PF04055; radical SAM domain-containing protein 4607551 4527416 MAV_4478 Mycobacterium avium 104 radical SAM domain-containing protein YP_883613.1 4606337 R 243243 CDS YP_883614.1 118464613 4526770 complement(4607548..4607859) 1 NC_008595.1 hypothetical protein 4607859 4526770 MAV_4479 Mycobacterium avium 104 hypothetical protein YP_883614.1 4607548 R 243243 CDS YP_883615.1 118466062 4530032 complement(4607862..4608020) 1 NC_008595.1 hypothetical protein 4608020 4530032 MAV_4480 Mycobacterium avium 104 hypothetical protein YP_883615.1 4607862 R 243243 CDS YP_883616.1 118463601 4527548 4608053..4608646 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4608646 4527548 MAV_4481 Mycobacterium avium 104 TetR family transcriptional regulator YP_883616.1 4608053 D 243243 CDS YP_883617.1 118466436 4527109 4608643..4609686 1 NC_008595.1 hypothetical protein 4609686 4527109 MAV_4482 Mycobacterium avium 104 hypothetical protein YP_883617.1 4608643 D 243243 CDS YP_883618.1 118463499 4529078 complement(4609720..4610580) 1 NC_008595.1 identified by match to protein family HMM PF00248; 2,5-diketo-D-gluconic acid reductase B 4610580 4529078 MAV_4483 Mycobacterium avium 104 2,5-diketo-D-gluconic acid reductase B YP_883618.1 4609720 R 243243 CDS YP_883619.1 118466903 4528417 4611026..4611853 1 NC_008595.1 identified by match to protein family HMM PF00459; inositol monophosphatase 4611853 4528417 MAV_4484 Mycobacterium avium 104 inositol monophosphatase YP_883619.1 4611026 D 243243 CDS YP_883620.1 118466396 4526198 complement(4611869..4613065) 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; ferredoxin reductase 4613065 4526198 MAV_4485 Mycobacterium avium 104 ferredoxin reductase YP_883620.1 4611869 R 243243 CDS YP_883621.2 161579552 4529209 complement(4613091..4613918) 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 4613918 4529209 MAV_4486 Mycobacterium avium 104 short chain dehydrogenase YP_883621.2 4613091 R 243243 CDS YP_883622.1 118464256 4527441 complement(4614010..4614858) 1 NC_008595.1 hypothetical protein 4614858 4527441 MAV_4487 Mycobacterium avium 104 hypothetical protein YP_883622.1 4614010 R 243243 CDS YP_883623.1 118463163 4529864 complement(4615870..4617060) 1 NC_008595.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4617060 tuf 4529864 tuf Mycobacterium avium 104 elongation factor Tu YP_883623.1 4615870 R 243243 CDS YP_883624.1 118465719 4527454 complement(4617231..4619336) 1 NC_008595.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 4619336 fusA 4527454 fusA Mycobacterium avium 104 elongation factor G YP_883624.1 4617231 R 243243 CDS YP_883625.1 118467289 4527247 complement(4619408..4619878) 1 NC_008595.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 4619878 rpsG 4527247 rpsG Mycobacterium avium 104 30S ribosomal protein S7 YP_883625.1 4619408 R 243243 CDS YP_883626.1 118466566 4529115 complement(4619878..4620252) 1 NC_008595.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 4620252 rpsL 4529115 rpsL Mycobacterium avium 104 30S ribosomal protein S12 YP_883626.1 4619878 R 243243 CDS YP_883627.1 118465571 4526757 4620318..4620431 1 NC_008595.1 hypothetical protein 4620431 4526757 MAV_4493 Mycobacterium avium 104 hypothetical protein YP_883627.1 4620318 D 243243 CDS YP_883628.1 118465892 4527926 complement(4620500..4621132) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4621132 4527926 MAV_4494 Mycobacterium avium 104 TetR family transcriptional regulator YP_883628.1 4620500 R 243243 CDS YP_883629.1 118465908 4528990 4621287..4621664 1 NC_008595.1 hypothetical protein 4621664 4528990 MAV_4495 Mycobacterium avium 104 hypothetical protein YP_883629.1 4621287 D 243243 CDS YP_883630.1 118465299 4526553 4621761..4622195 1 NC_008595.1 hypothetical protein 4622195 4526553 MAV_4496 Mycobacterium avium 104 hypothetical protein YP_883630.1 4621761 D 243243 CDS YP_883631.1 118464749 4527645 complement(4622210..4622977) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4622977 4527645 MAV_4497 Mycobacterium avium 104 enoyl-CoA hydratase YP_883631.1 4622210 R 243243 CDS YP_883632.1 118463619 4527323 complement(4622974..4623693) 1 NC_008595.1 identified by match to protein family HMM PF07848; match to protein family HMM PF08223; hypothetical protein 4623693 4527323 MAV_4498 Mycobacterium avium 104 hypothetical protein YP_883632.1 4622974 R 243243 CDS YP_883633.1 118462316 4529634 complement(4623696..4624634) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4624634 4529634 MAV_4499 Mycobacterium avium 104 enoyl-CoA hydratase YP_883633.1 4623696 R 243243 CDS YP_883634.1 118466870 4529822 complement(4624696..4626324) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4626324 4529822 MAV_4500 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883634.1 4624696 R 243243 CDS YP_883635.1 118466381 4526182 complement(4626385..4627362) 1 NC_008595.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 4627362 4526182 MAV_4501 Mycobacterium avium 104 endonuclease IV YP_883635.1 4626385 R 243243 CDS YP_883636.1 118467211 4529592 complement(4627384..4631334) 1 NC_008595.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4631334 rpoC 4529592 rpoC Mycobacterium avium 104 DNA-directed RNA polymerase subunit beta' YP_883636.1 4627384 R 243243 CDS YP_883637.1 118465939 4528498 complement(4631379..4634813) 1 NC_008595.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4634813 rpoB 4528498 rpoB Mycobacterium avium 104 DNA-directed RNA polymerase subunit beta YP_883637.1 4631379 R 243243 CDS YP_883638.1 118465382 4529673 complement(4635284..4636294) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 4636294 4529673 MAV_4504 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_883638.1 4635284 R 243243 CDS YP_883639.1 118464965 4528705 complement(4636466..4637971) 1 NC_008595.1 identified by match to protein family HMM PF03055; Sim14 protein 4637971 4528705 MAV_4505 Mycobacterium avium 104 Sim14 protein YP_883639.1 4636466 R 243243 CDS YP_883640.1 118464394 4528283 4638042..4638725 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4638725 4528283 MAV_4506 Mycobacterium avium 104 TetR family transcriptional regulator YP_883640.1 4638042 D 243243 CDS YP_883641.1 118464512 4525555 complement(4638786..4639178) 1 NC_008595.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4639178 rplL 4525555 rplL Mycobacterium avium 104 50S ribosomal protein L7/L12 YP_883641.1 4638786 R 243243 CDS YP_883642.1 118463739 4528147 complement(4639224..4639814) 1 NC_008595.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4639814 rplJ 4528147 rplJ Mycobacterium avium 104 50S ribosomal protein L10 YP_883642.1 4639224 R 243243 CDS YP_883643.1 118463476 4525529 complement(4640102..4640554) 1 NC_008595.1 hypothetical protein 4640554 4525529 MAV_4509 Mycobacterium avium 104 hypothetical protein YP_883643.1 4640102 R 243243 CDS YP_883644.1 118462660 4529088 complement(4640564..4641484) 1 NC_008595.1 identified by match to protein family HMM PF00480; sugar kinase 4641484 4529088 MAV_4510 Mycobacterium avium 104 sugar kinase YP_883644.1 4640564 R 243243 CDS YP_883645.1 118467189 4528423 complement(4641490..4642107) 1 NC_008595.1 FabD2 protein 4642107 4528423 MAV_4511 Mycobacterium avium 104 FabD2 protein YP_883645.1 4641490 R 243243 CDS YP_883646.1 118466710 4529717 complement(4642104..4646288) 1 NC_008595.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748; alpha-mannosidase 4646288 4529717 MAV_4512 Mycobacterium avium 104 alpha-mannosidase YP_883646.1 4642104 R 243243 CDS YP_883647.1 118467132 4526159 4646365..4646949 1 NC_008595.1 identified by match to protein family HMM PF04978; hypothetical protein 4646949 4526159 MAV_4513 Mycobacterium avium 104 hypothetical protein YP_883647.1 4646365 D 243243 CDS YP_883648.1 118464935 4528575 4647015..4648349 1 NC_008595.1 identified by match to protein family HMM PF03109; ABC transporter 4648349 4528575 MAV_4514 Mycobacterium avium 104 ABC transporter YP_883648.1 4647015 D 243243 CDS YP_883649.1 118465975 4528194 4648358..4649266 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4649266 4528194 MAV_4515 Mycobacterium avium 104 alpha/beta hydrolase YP_883649.1 4648358 D 243243 CDS YP_883650.1 118462474 4528728 4649356..4650216 1 NC_008595.1 identified by match to protein family HMM PF02353; methoxy mycolic acid synthase 1 4650216 4528728 MAV_4516 Mycobacterium avium 104 methoxy mycolic acid synthase 1 YP_883650.1 4649356 D 243243 CDS YP_883651.1 118466420 4530164 4650301..4651197 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1 4651197 4530164 MAV_4517 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase 1 YP_883651.1 4650301 D 243243 CDS YP_883652.1 118466358 4530498 4651291..4651989 1 NC_008595.1 identified by match to protein family HMM PF04946; DGPF domain-containing protein 4651989 4530498 MAV_4518 Mycobacterium avium 104 DGPF domain-containing protein YP_883652.1 4651291 D 243243 CDS YP_883653.1 118467229 4529786 4651994..4653256 1 NC_008595.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; RNA polymerase ECF-subfamily protein sigma factor 4653256 4529786 MAV_4519 Mycobacterium avium 104 RNA polymerase ECF-subfamily protein sigma factor YP_883653.1 4651994 D 243243 CDS YP_883654.1 118464910 4530745 complement(4653277..4653984) 1 NC_008595.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4653984 rplA 4530745 rplA Mycobacterium avium 104 50S ribosomal protein L1 YP_883654.1 4653277 R 243243 CDS YP_883655.1 118465827 4525499 complement(4654120..4654548) 1 NC_008595.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4654548 rplK 4525499 rplK Mycobacterium avium 104 50S ribosomal protein L11 YP_883655.1 4654120 R 243243 CDS YP_883656.1 118466107 4527736 complement(4654595..4655365) 1 NC_008595.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4655365 nusG 4527736 nusG Mycobacterium avium 104 transcription antitermination protein NusG YP_883656.1 4654595 R 243243 CDS YP_883657.1 118466490 4527620 complement(4655408..4655851) 1 NC_008595.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4655851 secE 4527620 secE Mycobacterium avium 104 preprotein translocase subunit SecE YP_883657.1 4655408 R 243243 CDS YP_883658.1 118467224 4529605 complement(4656161..4656664) 1 NC_008595.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadC 4656664 4529605 MAV_4525 Mycobacterium avium 104 (3R)-hydroxyacyl-ACP dehydratase subunit HadC YP_883658.1 4656161 R 243243 CDS YP_883659.1 118462426 4528289 complement(4656668..4657072) 1 NC_008595.1 functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadB 4657072 4528289 MAV_4526 Mycobacterium avium 104 (3R)-hydroxyacyl-ACP dehydratase subunit HadB YP_883659.1 4656668 R 243243 CDS YP_883660.1 118463130 4529655 complement(4657083..4657562) 1 NC_008595.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; (3R)-hydroxyacyl-ACP dehydratase subunit HadA 4657562 4529655 MAV_4527 Mycobacterium avium 104 (3R)-hydroxyacyl-ACP dehydratase subunit HadA YP_883660.1 4657083 R 243243 CDS YP_883661.1 118464989 4527481 complement(4657611..4657742) 1 NC_008595.1 identified by match to protein family HMM PF00471; match to protein family HMM TIGR01023; ribosomal protein L33 4657742 rpmG 4527481 rpmG Mycobacterium avium 104 ribosomal protein L33 YP_883661.1 4657611 R 243243 CDS YP_883662.1 118465705 4530327 complement(4658107..4658313) 1 NC_008595.1 hypothetical protein 4658313 4530327 MAV_4531 Mycobacterium avium 104 hypothetical protein YP_883662.1 4658107 R 243243 CDS YP_883663.1 118466087 4527355 4658438..4659151 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 4659151 4527355 MAV_4532 Mycobacterium avium 104 metallo-beta-lactamase YP_883663.1 4658438 D 243243 CDS YP_883664.1 118466633 4526989 4659222..4660055 1 NC_008595.1 hypothetical protein 4660055 4526989 MAV_4533 Mycobacterium avium 104 hypothetical protein YP_883664.1 4659222 D 243243 CDS YP_883665.1 118467204 4528439 4660072..4660767 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4660767 4528439 MAV_4534 Mycobacterium avium 104 enoyl-CoA hydratase YP_883665.1 4660072 D 243243 CDS YP_883666.1 118464940 4528201 4660820..4663186 1 NC_008595.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; nitrate reductase NarB 4663186 4528201 MAV_4535 Mycobacterium avium 104 nitrate reductase NarB YP_883666.1 4660820 D 243243 CDS YP_883667.1 118464694 4527883 4663183..4663662 1 NC_008595.1 hypothetical protein 4663662 4527883 MAV_4536 Mycobacterium avium 104 hypothetical protein YP_883667.1 4663183 D 243243 CDS YP_883668.1 118463518 4527698 complement(4663750..4664772) 1 NC_008595.1 identified by match to protein family HMM PF01734; phospholipase, patatin family protein 4664772 4527698 MAV_4537 Mycobacterium avium 104 phospholipase, patatin family protein YP_883668.1 4663750 R 243243 CDS YP_883669.1 118463112 4527174 complement(4664773..4665240) 1 NC_008595.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 4665240 cynS 4527174 cynS Mycobacterium avium 104 cyanate hydratase YP_883669.1 4664773 R 243243 CDS YP_883670.1 118463092 4528915 complement(4665309..4666058) 1 NC_008595.1 identified by match to protein family HMM PF01170; match to protein family HMM PF05175; methyltransferase small domain-containing protein 4666058 4528915 MAV_4539 Mycobacterium avium 104 methyltransferase small domain-containing protein YP_883670.1 4665309 R 243243 CDS YP_883671.1 118462381 4529194 complement(4666110..4666625) 1 NC_008595.1 identified by match to protein family HMM PF00881; nitroreductase 4666625 4529194 MAV_4540 Mycobacterium avium 104 nitroreductase YP_883671.1 4666110 R 243243 CDS YP_883672.1 118466544 4527012 4666888..4667754 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1 4667754 4527012 MAV_4541 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase 1 YP_883672.1 4666888 D 243243 CDS YP_883673.1 118465804 4526117 4667794..4671084 1 NC_008595.1 identified by match to protein family HMM PF04257; match to protein family HMM TIGR01450; exodeoxyribonuclease V, gamma subunit 4671084 recC 4526117 recC Mycobacterium avium 104 exodeoxyribonuclease V, gamma subunit YP_883673.1 4667794 D 243243 CDS YP_883674.1 118465710 4530332 4671084..4674386 1 NC_008595.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR00609; exodeoxyribonuclease V, beta subunit 4674386 recB 4530332 recB Mycobacterium avium 104 exodeoxyribonuclease V, beta subunit YP_883674.1 4671084 D 243243 CDS YP_883675.1 118463540 4526807 4674395..4676107 1 NC_008595.1 identified by match to protein family HMM TIGR01447; exodeoxyribonuclease V, alpha subunit 4676107 recD 4526807 recD Mycobacterium avium 104 exodeoxyribonuclease V, alpha subunit YP_883675.1 4674395 D 243243 CDS YP_883676.1 118466458 4528679 4676116..4676817 1 NC_008595.1 hypothetical protein 4676817 4528679 MAV_4545 Mycobacterium avium 104 hypothetical protein YP_883676.1 4676116 D 243243 CDS YP_883677.1 118463921 4528101 complement(4676831..4678357) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; mce-family protein mce2f 4678357 4528101 MAV_4546 Mycobacterium avium 104 mce-family protein mce2f YP_883677.1 4676831 R 243243 CDS YP_883678.1 118462367 4529179 complement(4678373..4679551) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4679551 4529179 MAV_4547 Mycobacterium avium 104 virulence factor Mce YP_883678.1 4678373 R 243243 CDS YP_883679.1 118464414 4530808 complement(4679512..4681011) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4681011 4530808 MAV_4548 Mycobacterium avium 104 virulence factor Mce YP_883679.1 4679512 R 243243 CDS YP_883680.1 118463703 4530590 complement(4681008..4682450) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; mce-family protein mce2c 4682450 4530590 MAV_4549 Mycobacterium avium 104 mce-family protein mce2c YP_883680.1 4681008 R 243243 CDS YP_883681.1 118465867 4527509 complement(4682447..4683478) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4683478 4527509 MAV_4550 Mycobacterium avium 104 virulence factor Mce YP_883681.1 4682447 R 243243 CDS YP_883682.1 118465139 4529170 complement(4683475..4684689) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 4684689 4529170 MAV_4551 Mycobacterium avium 104 virulence factor Mce YP_883682.1 4683475 R 243243 CDS YP_883683.1 118467306 4530298 complement(4684695..4685573) 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 4685573 4530298 MAV_4552 Mycobacterium avium 104 hypothetical protein YP_883683.1 4684695 R 243243 CDS YP_883684.1 118466592 4529358 complement(4685575..4686357) 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 4686357 4529358 MAV_4553 Mycobacterium avium 104 hypothetical protein YP_883684.1 4685575 R 243243 CDS YP_883685.1 118465218 4529855 4687086..4687454 1 NC_008595.1 identified by match to protein family HMM PF03693; match to protein family HMM TIGR02606; addiction module antidote protein, CC2985 family protein 4687454 4529855 MAV_4555 Mycobacterium avium 104 addiction module antidote protein, CC2985 family protein YP_883685.1 4687086 D 243243 CDS YP_883686.1 118462615 4526417 4687517..4687828 1 NC_008595.1 monooxygenase 4687828 4526417 MAV_4556 Mycobacterium avium 104 monooxygenase YP_883686.1 4687517 D 243243 CDS YP_883687.1 118464744 4529431 complement(4687839..4688786) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4688786 4529431 MAV_4557 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883687.1 4687839 R 243243 CDS YP_883688.1 118466587 4527377 complement(4688783..4689745) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4689745 4527377 MAV_4558 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883688.1 4688783 R 243243 CDS YP_883689.1 118466190 4530180 4689915..4692290 1 NC_008595.1 identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374; hypothetical protein 4692290 4530180 MAV_4559 Mycobacterium avium 104 hypothetical protein YP_883689.1 4689915 D 243243 CDS YP_883690.1 118465468 4526236 complement(4692294..4694930) 1 NC_008595.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180; alpha-1,2-mannosidase 4694930 4526236 MAV_4560 Mycobacterium avium 104 alpha-1,2-mannosidase YP_883690.1 4692294 R 243243 CDS YP_883691.1 118464325 4529830 4695141..4695800 1 NC_008595.1 LpqN protein 4695800 4529830 MAV_4561 Mycobacterium avium 104 LpqN protein YP_883691.1 4695141 D 243243 CDS YP_883692.1 118463908 4525839 complement(4695813..4696505) 1 NC_008595.1 identified by match to protein family HMM PF03861; ANTAR domain-containing protein 4696505 4525839 MAV_4562 Mycobacterium avium 104 ANTAR domain-containing protein YP_883692.1 4695813 R 243243 CDS YP_883693.1 118464928 4528568 complement(4696692..4697447) 1 NC_008595.1 identified by match to protein family HMM PF01927; hypothetical protein 4697447 4528568 MAV_4563 Mycobacterium avium 104 hypothetical protein YP_883693.1 4696692 R 243243 CDS YP_883694.1 118466052 4528060 complement(4697444..4698535) 1 NC_008595.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 4698535 galK 4528060 galK Mycobacterium avium 104 galactokinase YP_883694.1 4697444 R 243243 CDS YP_883695.1 118467060 4526438 complement(4698532..4699641) 1 NC_008595.1 identified by match to protein family HMM PF01087; match to protein family HMM PF02744; match to protein family HMM TIGR00209; galactose-1-phosphate uridylyltransferase 4699641 galT 4526438 galT Mycobacterium avium 104 galactose-1-phosphate uridylyltransferase YP_883695.1 4698532 R 243243 CDS YP_883696.1 118466461 4528682 4699742..4701925 1 NC_008595.1 hypothetical protein 4701925 4528682 MAV_4566 Mycobacterium avium 104 hypothetical protein YP_883696.1 4699742 D 243243 CDS YP_883697.1 118466290 4529536 complement(4701965..4702834) 1 NC_008595.1 identified by match to protein family HMM PF00561; dihydrolipoyllysine-residue acetyltransferase component of acetoincleaving system 4702834 4529536 MAV_4567 Mycobacterium avium 104 dihydrolipoyllysine-residue acetyltransferase component of acetoincleaving system YP_883697.1 4701965 R 243243 CDS YP_883698.1 118463148 4527786 4702909..4703763 1 NC_008595.1 identified by match to protein family HMM PF01936; hypothetical protein 4703763 4527786 MAV_4568 Mycobacterium avium 104 hypothetical protein YP_883698.1 4702909 D 243243 CDS YP_883699.1 118462760 4527850 4703960..4705189 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 superfamily protein 4705189 4527850 MAV_4569 Mycobacterium avium 104 cytochrome P450 superfamily protein YP_883699.1 4703960 D 243243 CDS YP_883700.1 118464169 4526479 4705375..4706604 1 NC_008595.1 hypothetical protein 4706604 4526479 MAV_4570 Mycobacterium avium 104 hypothetical protein YP_883700.1 4705375 D 243243 CDS YP_883701.1 118463879 4527757 complement(4706607..4707905) 1 NC_008595.1 identified by match to protein family HMM PF01566; metal ion transporter, NRAMP family protein 4707905 4527757 MAV_4571 Mycobacterium avium 104 metal ion transporter, NRAMP family protein YP_883701.1 4706607 R 243243 CDS YP_883702.1 118466026 4529912 4708167..4709108 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase 4709108 4529912 MAV_4573 Mycobacterium avium 104 methyltransferase YP_883702.1 4708167 D 243243 CDS YP_883703.1 118463124 4529649 complement(4709105..4709524) 1 NC_008595.1 hypothetical protein 4709524 4529649 MAV_4572 Mycobacterium avium 104 hypothetical protein YP_883703.1 4709105 R 243243 CDS YP_883704.1 118463825 4526042 4710000..4710491 1 NC_008595.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 4710491 4526042 MAV_4575 Mycobacterium avium 104 nucleotide-binding protein YP_883704.1 4710000 D 243243 CDS YP_883705.1 118465534 4530010 4710618..4712138 1 NC_008595.1 monooxygenase, flavin-binding family protein 4712138 4530010 MAV_4576 Mycobacterium avium 104 monooxygenase, flavin-binding family protein YP_883705.1 4710618 D 243243 CDS YP_883706.1 118464850 4527966 4712207..4713232 1 NC_008595.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4713232 4527966 MAV_4577 Mycobacterium avium 104 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_883706.1 4712207 D 243243 CDS YP_883707.1 118466975 4530374 4713477..4715012 1 NC_008595.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; carbonate dehydratase 4715012 4530374 MAV_4578 Mycobacterium avium 104 carbonate dehydratase YP_883707.1 4713477 D 243243 CDS YP_883708.1 118466302 4528344 complement(4715030..4715290) 1 NC_008595.1 identified by match to protein family HMM PF01381; transcriptional regulator 4715290 4528344 MAV_4579 Mycobacterium avium 104 transcriptional regulator YP_883708.1 4715030 R 243243 CDS YP_883709.1 118466539 4527007 complement(4715394..4716257) 1 NC_008595.1 metalloprotease; heat shock protein HtpX 4716257 4527007 MAV_4580 Mycobacterium avium 104 heat shock protein HtpX YP_883709.1 4715394 R 243243 CDS YP_883710.1 118463064 4527563 complement(4716351..4717328) 1 NC_008595.1 identified by match to protein family HMM PF00348; polyprenyl synthetase 4717328 4527563 MAV_4581 Mycobacterium avium 104 polyprenyl synthetase YP_883710.1 4716351 R 243243 CDS YP_883711.1 118462825 4528639 4717375..4718619 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF04820; match to protein family HMM PF05834; match to protein family HMM PF07992; match to protein family HMM TIGR02032; FAD dependent oxidoreductase, putative 4718619 4528639 MAV_4582 Mycobacterium avium 104 FAD dependent oxidoreductase, putative YP_883711.1 4717375 D 243243 CDS YP_883712.1 118462525 4527668 4718652..4719056 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 4719056 4527668 MAV_4583 Mycobacterium avium 104 hypothetical protein YP_883712.1 4718652 D 243243 CDS YP_883713.1 118463483 4529061 complement(4719064..4719807) 1 NC_008595.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4719807 ubiE 4529061 ubiE Mycobacterium avium 104 ubiquinone/menaquinone biosynthesis methyltransferase YP_883713.1 4719064 R 243243 CDS YP_883714.1 118462628 4526430 4719839..4720024 1 NC_008595.1 short chain dehydrogenase 4720024 4526430 MAV_4585 Mycobacterium avium 104 short chain dehydrogenase YP_883714.1 4719839 D 243243 CDS YP_883715.1 118464871 4530707 complement(4720041..4721195) 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyl transferase 4721195 4530707 MAV_4586 Mycobacterium avium 104 glycosyl transferase YP_883715.1 4720041 R 243243 CDS YP_883716.1 118465568 4526754 complement(4721247..4721750) 1 NC_008595.1 hypothetical protein 4721750 4526754 MAV_4587 Mycobacterium avium 104 hypothetical protein YP_883716.1 4721247 R 243243 CDS YP_883717.1 118464066 4529506 complement(4721768..4723405) 1 NC_008595.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 4723405 4529506 MAV_4588 Mycobacterium avium 104 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_883717.1 4721768 R 243243 CDS YP_883718.1 118464762 4527658 complement(4723501..4724286) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 4724286 4527658 MAV_4589 Mycobacterium avium 104 alpha/beta hydrolase YP_883718.1 4723501 R 243243 CDS YP_883719.1 118464769 4529124 complement(4724283..4725263) 1 NC_008595.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 4725263 4529124 MAV_4590 Mycobacterium avium 104 O-succinylbenzoate synthase YP_883719.1 4724283 R 243243 CDS YP_883720.1 118462587 4530208 complement(4725260..4726870) 1 NC_008595.1 identified by match to protein family HMM PF07969; amidohydrolase 4726870 4530208 MAV_4591 Mycobacterium avium 104 amidohydrolase YP_883720.1 4725260 R 243243 CDS YP_883721.1 118463273 4530521 4726983..4728584 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 4728584 4530521 MAV_4592 Mycobacterium avium 104 acyl-CoA synthetase YP_883721.1 4726983 D 243243 CDS YP_883722.1 118466884 4526703 complement(4728826..4729365) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4729365 4526703 MAV_4593 Mycobacterium avium 104 TetR family transcriptional regulator YP_883722.1 4728826 R 243243 CDS YP_883723.1 118462592 4530213 4729454..4730374 1 NC_008595.1 identified by match to protein family HMM PF00248; oxidoreductase YdbC 4730374 4530213 MAV_4594 Mycobacterium avium 104 oxidoreductase YdbC YP_883723.1 4729454 D 243243 CDS YP_883724.1 118463311 4529551 4730361..4730816 1 NC_008595.1 identified by match to protein family HMM TIGR00026; mycobacterium tuberculosis paralogous family protein 11; cell entry (mce) related family protein 4730816 4529551 MAV_4595 Mycobacterium avium 104 cell entry (mce) related family protein YP_883724.1 4730361 D 243243 CDS YP_883725.1 118465781 4526916 4730860..4731723 1 NC_008595.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 4731723 menB 4526916 menB Mycobacterium avium 104 naphthoate synthase YP_883725.1 4730860 D 243243 CDS YP_883726.1 118465383 4529675 4731881..4732777 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 4732777 4529675 MAV_4597 Mycobacterium avium 104 short chain dehydrogenase YP_883726.1 4731881 D 243243 CDS YP_883727.1 118467222 4529603 4732805..4733212 1 NC_008595.1 identified by match to protein family HMM PF00903; hypothetical protein 4733212 4529603 MAV_4598 Mycobacterium avium 104 hypothetical protein YP_883727.1 4732805 D 243243 CDS YP_883728.1 118466793 4529351 4733310..4734551 1 NC_008595.1 identified by match to protein family HMM PF01384; phosphate transporter 4734551 4529351 MAV_4599 Mycobacterium avium 104 phosphate transporter YP_883728.1 4733310 D 243243 CDS YP_883729.1 118462786 4525754 4734548..4734856 1 NC_008595.1 hypothetical protein 4734856 4525754 MAV_4600 Mycobacterium avium 104 hypothetical protein YP_883729.1 4734548 D 243243 CDS YP_883730.1 118463005 4530635 4734970..4735215 1 NC_008595.1 hypothetical protein 4735215 4530635 MAV_4601 Mycobacterium avium 104 hypothetical protein YP_883730.1 4734970 D 243243 CDS YP_883731.1 118464470 4527063 4735284..4736375 1 NC_008595.1 identified by match to protein family HMM PF00501; O-succinylbenzoic acid--CoA ligase 4736375 4527063 MAV_4602 Mycobacterium avium 104 O-succinylbenzoic acid--CoA ligase YP_883731.1 4735284 D 243243 CDS YP_883732.1 118463924 4528104 4736411..4737763 1 NC_008595.1 integral membrane protein 4737763 4528104 MAV_4603 Mycobacterium avium 104 integral membrane protein YP_883732.1 4736411 D 243243 CDS YP_883733.1 118462856 4526038 complement(4737772..4738428) 1 NC_008595.1 hypothetical protein 4738428 4526038 MAV_4604 Mycobacterium avium 104 hypothetical protein YP_883733.1 4737772 R 243243 CDS YP_883734.1 118462368 4529180 complement(4738425..4739087) 1 NC_008595.1 identified by match to protein family HMM PF00535; glycosyltransferase 4739087 4529180 MAV_4605 Mycobacterium avium 104 glycosyltransferase YP_883734.1 4738425 R 243243 CDS YP_883735.1 118464734 4529421 complement(4739091..4740761) 1 NC_008595.1 hypothetical protein 4740761 4529421 MAV_4606 Mycobacterium avium 104 hypothetical protein YP_883735.1 4739091 R 243243 CDS YP_883736.1 118462559 4528618 complement(4740843..4740995) 1 NC_008595.1 hypothetical protein 4740995 4528618 MAV_4607 Mycobacterium avium 104 hypothetical protein YP_883736.1 4740843 R 243243 CDS YP_883737.1 118466261 4526880 4741071..4742798 1 NC_008595.1 hypothetical protein 4742798 4526880 MAV_4608 Mycobacterium avium 104 hypothetical protein YP_883737.1 4741071 D 243243 CDS YP_883738.1 118466473 4527603 complement(4742802..4743824) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD-dependent epimerase/dehydratase 4743824 4527603 MAV_4609 Mycobacterium avium 104 NAD-dependent epimerase/dehydratase YP_883738.1 4742802 R 243243 CDS YP_883739.1 118465503 4526800 complement(4743827..4744621) 1 NC_008595.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 4744621 mtaP 4526800 mtaP Mycobacterium avium 104 5'-methylthioadenosine phosphorylase YP_883739.1 4743827 R 243243 CDS YP_883740.1 118462576 4528635 4744673..4745545 1 NC_008595.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4745545 menA 4528635 menA Mycobacterium avium 104 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_883740.1 4744673 D 243243 CDS YP_883741.1 118463479 4525532 4745629..4746636 1 NC_008595.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 4746636 4525532 MAV_4612 Mycobacterium avium 104 3-oxoacyl-(acyl carrier protein) synthase III YP_883741.1 4745629 D 243243 CDS YP_883742.1 118465068 4527044 complement(4746641..4746967) 1 NC_008595.1 hypothetical protein 4746967 4527044 MAV_4613 Mycobacterium avium 104 hypothetical protein YP_883742.1 4746641 R 243243 CDS YP_883743.1 118465603 4527862 4747023..4747184 1 NC_008595.1 hypothetical protein 4747184 4527862 MAV_4614 Mycobacterium avium 104 hypothetical protein YP_883743.1 4747023 D 243243 CDS YP_883744.1 118463940 4526592 complement(4747219..4748517) 1 NC_008595.1 hypothetical protein 4748517 4526592 MAV_4615 Mycobacterium avium 104 hypothetical protein YP_883744.1 4747219 R 243243 CDS YP_883745.1 118464525 4529445 complement(4748562..4749539) 1 NC_008595.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144; cytochrome C-type biogenesis protein CcsB 4749539 ccsB 4529445 ccsB Mycobacterium avium 104 cytochrome C-type biogenesis protein CcsB YP_883745.1 4748562 R 243243 CDS YP_883746.1 118462767 4527264 complement(4749536..4751176) 1 NC_008595.1 identified by match to protein family HMM PF05140; hypothetical protein 4751176 4527264 MAV_4617 Mycobacterium avium 104 hypothetical protein YP_883746.1 4749536 R 243243 CDS YP_883747.1 118463497 4529076 complement(4751176..4751955) 1 NC_008595.1 identified by match to protein family HMM PF02683; cytochrome C biogenesis protein transmembrane region 4751955 4529076 MAV_4618 Mycobacterium avium 104 cytochrome C biogenesis protein transmembrane region YP_883747.1 4751176 R 243243 CDS YP_883748.1 118465689 4525748 complement(4751952..4752545) 1 NC_008595.1 hypothetical protein 4752545 4525748 MAV_4619 Mycobacterium avium 104 hypothetical protein YP_883748.1 4751952 R 243243 CDS YP_883749.1 118466233 4526579 complement(4752542..4753150) 1 NC_008595.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 4753150 4526579 MAV_4620 Mycobacterium avium 104 phosphoglycerate mutase YP_883749.1 4752542 R 243243 CDS YP_883750.1 118465748 4525711 complement(4753150..4754487) 1 NC_008595.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 4754487 hemL 4525711 hemL Mycobacterium avium 104 glutamate-1-semialdehyde aminotransferase YP_883750.1 4753150 R 243243 CDS YP_883751.1 118466129 4529762 complement(4754546..4754890) 1 NC_008595.1 hypothetical protein 4754890 4529762 MAV_4622 Mycobacterium avium 104 hypothetical protein YP_883751.1 4754546 R 243243 CDS YP_883752.1 118463706 4530593 4754932..4755360 1 NC_008595.1 identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026; hypothetical protein 4755360 4530593 MAV_4623 Mycobacterium avium 104 hypothetical protein YP_883752.1 4754932 D 243243 CDS YP_883753.1 118464461 4527054 4755371..4756552 1 NC_008595.1 identified by match to protein family HMM PF01188; mandelate racemase/muconate lactonizing enzyme 4756552 4527054 MAV_4624 Mycobacterium avium 104 mandelate racemase/muconate lactonizing enzyme YP_883753.1 4755371 D 243243 CDS YP_883754.1 118462253 4526939 4756549..4757466 1 NC_008595.1 identified by match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF03721; match to protein family HMM PF03807; match to protein family HMM TIGR00745; 2-dehydropantoate 2-reductase 4757466 panE 4526939 panE Mycobacterium avium 104 2-dehydropantoate 2-reductase YP_883754.1 4756549 D 243243 CDS YP_883755.1 118462982 4527410 complement(4757537..4758886) 1 NC_008595.1 identified by match to protein family HMM PF00324; gaba permease 4758886 4527410 MAV_4626 Mycobacterium avium 104 gaba permease YP_883755.1 4757537 R 243243 CDS YP_883756.1 118465960 4528179 complement(4758947..4760296) 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator superfamily protein 4760296 4528179 MAV_4627 Mycobacterium avium 104 major facilitator superfamily protein YP_883756.1 4758947 R 243243 CDS YP_883757.1 118466661 4526611 complement(4760302..4761447) 1 NC_008595.1 identified by similarity to SP:P40402; alkanesulfonate monoxygenase 4761447 4526611 MAV_4628 Mycobacterium avium 104 alkanesulfonate monoxygenase YP_883757.1 4760302 R 243243 CDS YP_883758.1 118464549 4530419 4761939..4762769 1 NC_008595.1 identified by match to protein family HMM PF00756; esterase 4762769 4530419 MAV_4629 Mycobacterium avium 104 esterase YP_883758.1 4761939 D 243243 CDS YP_883759.1 118465263 4527284 4762821..4764941 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase domain-containing protein 4764941 4527284 MAV_4630 Mycobacterium avium 104 acyltransferase domain-containing protein YP_883759.1 4762821 D 243243 CDS YP_883760.1 118464729 4529416 4765007..4765123 1 NC_008595.1 hypothetical protein 4765123 4529416 MAV_4631 Mycobacterium avium 104 hypothetical protein YP_883760.1 4765007 D 243243 CDS YP_883761.1 118465293 4529329 complement(4765132..4765821) 1 NC_008595.1 identified by match to protein family HMM PF00657; hypothetical protein 4765821 4529329 MAV_4632 Mycobacterium avium 104 hypothetical protein YP_883761.1 4765132 R 243243 CDS YP_883762.1 118463119 4527181 complement(4765912..4767150) 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase, putative 4767150 4527181 MAV_4633 Mycobacterium avium 104 acyltransferase, putative YP_883762.1 4765912 R 243243 CDS YP_883763.1 118462779 4527276 4767516..4767956 1 NC_008595.1 identified by match to protein family HMM PF01740; STAS domain-containing protein 4767956 4527276 MAV_4635 Mycobacterium avium 104 STAS domain-containing protein YP_883763.1 4767516 D 243243 CDS YP_883764.1 118463663 4525955 complement(4767940..4768200) 1 NC_008595.1 transmembrane protein 4768200 4525955 MAV_4634 Mycobacterium avium 104 transmembrane protein YP_883764.1 4767940 R 243243 CDS YP_883765.1 118463652 4528554 complement(4768197..4768682) 1 NC_008595.1 hypothetical protein 4768682 4528554 MAV_4636 Mycobacterium avium 104 hypothetical protein YP_883765.1 4768197 R 243243 CDS YP_883766.1 118463957 4526609 complement(4768771..4769658) 1 NC_008595.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 4769658 hemB 4526609 hemB Mycobacterium avium 104 delta-aminolevulinic acid dehydratase YP_883766.1 4768771 R 243243 CDS YP_883767.1 118465929 4528488 complement(4769758..4771371) 1 NC_008595.1 identified by match to protein family HMM PF00590; match to protein family HMM PF02602; uroporphyrinogen-III synthase 4771371 hemD 4528488 hemD Mycobacterium avium 104 uroporphyrinogen-III synthase YP_883767.1 4769758 R 243243 CDS YP_883768.1 118467030 4526542 complement(4771440..4772387) 1 NC_008595.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4772387 hemC 4526542 hemC Mycobacterium avium 104 porphobilinogen deaminase YP_883768.1 4771440 R 243243 CDS YP_883769.1 118466494 4525577 complement(4772401..4773780) 1 NC_008595.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 4773780 hemA 4525577 hemA Mycobacterium avium 104 glutamyl-tRNA reductase YP_883769.1 4772401 R 243243 CDS YP_883770.1 118463078 4527577 complement(4773891..4774160) 1 NC_008595.1 identified by match to protein family HMM PF05768; hypothetical protein 4774160 4527577 MAV_4641 Mycobacterium avium 104 hypothetical protein YP_883770.1 4773891 R 243243 CDS YP_883771.1 118462464 4528718 4774220..4774528 1 NC_008595.1 identified by match to protein family HMM PF06013; hypothetical protein 4774528 4528718 MAV_4642 Mycobacterium avium 104 hypothetical protein YP_883771.1 4774220 D 243243 CDS YP_883772.1 118465918 4529000 4774521..4774811 1 NC_008595.1 hypothetical protein 4774811 4529000 MAV_4643 Mycobacterium avium 104 hypothetical protein YP_883772.1 4774521 D 243243 CDS YP_883773.1 118464783 4529138 4774816..4777293 1 NC_008595.1 hypothetical protein 4777293 4529138 MAV_4644 Mycobacterium avium 104 hypothetical protein YP_883773.1 4774816 D 243243 CDS YP_883774.1 118463098 4528921 4778033..4778944 1 NC_008595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01488; match to protein family HMM TIGR01490; HAD-superfamily protein subfamily protein IB hydrolase 4778944 4528921 MAV_4645 Mycobacterium avium 104 HAD-superfamily protein subfamily protein IB hydrolase YP_883774.1 4778033 D 243243 CDS YP_883775.1 118467143 4527157 4778989..4779513 1 NC_008595.1 hypothetical protein 4779513 4527157 MAV_4646 Mycobacterium avium 104 hypothetical protein YP_883775.1 4778989 D 243243 CDS YP_883776.1 118465133 4529164 4779514..4780413 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 2 4780413 4529164 MAV_4647 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase 2 YP_883776.1 4779514 D 243243 CDS YP_883777.1 118463817 4526073 complement(4780513..4781577) 1 NC_008595.1 identified by match to protein family HMM PF01553; acyltransferase 4781577 4526073 MAV_4648 Mycobacterium avium 104 acyltransferase YP_883777.1 4780513 R 243243 CDS YP_883778.1 118464393 4528282 complement(4781583..4782710) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 4782710 4528282 MAV_4649 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_883778.1 4781583 R 243243 CDS YP_883779.1 118464234 4528607 complement(4782762..4782863) 1 NC_008595.1 identified by match to protein family HMM PF08213; hypothetical protein 4782863 4528607 MAV_4650 Mycobacterium avium 104 hypothetical protein YP_883779.1 4782762 R 243243 CDS YP_883780.1 118462235 4525573 complement(4782998..4783135) 1 NC_008595.1 identified by match to protein family HMM TIGR01764; hypothetical protein 4783135 4525573 MAV_4651 Mycobacterium avium 104 hypothetical protein YP_883780.1 4782998 R 243243 CDS YP_883781.1 118463455 4529697 complement(4783394..4784281) 1 NC_008595.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 4784281 proC 4529697 proC Mycobacterium avium 104 pyrroline-5-carboxylate reductase YP_883781.1 4783394 R 243243 CDS YP_883782.1 118466166 4528789 complement(4784297..4785139) 1 NC_008595.1 hypothetical protein 4785139 4528789 MAV_4653 Mycobacterium avium 104 hypothetical protein YP_883782.1 4784297 R 243243 CDS YP_883783.1 118465223 4529860 complement(4785164..4786006) 1 NC_008595.1 identified by match to protein family HMM PF01261; hypothetical protein 4786006 4529860 MAV_4654 Mycobacterium avium 104 hypothetical protein YP_883783.1 4785164 R 243243 CDS YP_883784.1 118466176 4526207 complement(4786022..4786990) 1 NC_008595.1 hypothetical protein 4786990 4526207 MAV_4655 Mycobacterium avium 104 hypothetical protein YP_883784.1 4786022 R 243243 CDS YP_883785.1 118464201 4529312 complement(4786987..4788003) 1 NC_008595.1 identified by match to protein family HMM PF02541; Ppx/GppA phosphatase 4788003 4529312 MAV_4656 Mycobacterium avium 104 Ppx/GppA phosphatase YP_883785.1 4786987 R 243243 CDS YP_883786.1 118463123 4529648 4788122..4788925 1 NC_008595.1 hypothetical protein 4788925 4529648 MAV_4657 Mycobacterium avium 104 hypothetical protein YP_883786.1 4788122 D 243243 CDS YP_883787.1 118462575 4528634 4788945..4789889 1 NC_008595.1 hypothetical protein 4789889 4528634 MAV_4658 Mycobacterium avium 104 hypothetical protein YP_883787.1 4788945 D 243243 CDS YP_883788.1 118467148 4527162 4789886..4790386 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, nudix family protein, putative 4790386 4527162 MAV_4659 Mycobacterium avium 104 hydrolase, nudix family protein, putative YP_883788.1 4789886 D 243243 CDS YP_883789.1 118466224 4528904 complement(4790387..4791070) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 4791070 4528904 MAV_4660 Mycobacterium avium 104 DNA-binding response regulator YP_883789.1 4790387 R 243243 CDS YP_883790.1 118465980 4526122 complement(4791332..4792555) 1 NC_008595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; hisitidine protein kinase SenX3 4792555 4526122 MAV_4661 Mycobacterium avium 104 hisitidine protein kinase SenX3 YP_883790.1 4791332 R 243243 CDS YP_883791.1 118463185 4527708 complement(4792726..4793475) 1 NC_008595.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 4793475 gpmA 4527708 gpmA Mycobacterium avium 104 phosphoglyceromutase YP_883791.1 4792726 R 243243 CDS YP_883792.1 118466618 4526856 complement(4793529..4794038) 1 NC_008595.1 hypothetical protein 4794038 4526856 MAV_4663 Mycobacterium avium 104 hypothetical protein YP_883792.1 4793529 R 243243 CDS YP_883793.1 118465529 4530002 complement(4794035..4795309) 1 NC_008595.1 identified by match to protein family HMM PF00534; hypothetical protein 4795309 4530002 MAV_4664 Mycobacterium avium 104 hypothetical protein YP_883793.1 4794035 R 243243 CDS YP_883794.1 118464805 4527624 complement(4795373..4796659) 1 NC_008595.1 identified by match to protein family HMM PF00480; ROK family protein 4796659 4527624 MAV_4665 Mycobacterium avium 104 ROK family protein YP_883794.1 4795373 R 243243 CDS YP_883795.1 118464648 4528245 4796886..4797635 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; oxidoreductase 4797635 4528245 MAV_4667 Mycobacterium avium 104 oxidoreductase YP_883795.1 4796886 D 243243 CDS YP_883796.1 118465375 4529666 complement(4797619..4798950) 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 4798950 4529666 MAV_4666 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_883796.1 4797619 R 243243 CDS YP_883797.1 118462379 4529192 complement(4799032..4800150) 1 NC_008595.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4800150 murB 4529192 murB Mycobacterium avium 104 UDP-N-acetylenolpyruvoylglucosamine reductase YP_883797.1 4799032 R 243243 CDS YP_883798.1 118466918 4529463 4800845..4801669 1 NC_008595.1 identified by match to protein family HMM PF00795; carbon-nitrogen hydrolase 4801669 4529463 MAV_4670 Mycobacterium avium 104 carbon-nitrogen hydrolase YP_883798.1 4800845 D 243243 CDS YP_883799.1 118466216 4528895 4801666..4802724 1 NC_008595.1 hypothetical protein 4802724 4528895 MAV_4671 Mycobacterium avium 104 hypothetical protein YP_883799.1 4801666 D 243243 CDS YP_883800.1 118464952 4528214 complement(4802737..4803408) 1 NC_008595.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4803408 deoC 4528214 deoC Mycobacterium avium 104 deoxyribose-phosphate aldolase YP_883800.1 4802737 R 243243 CDS YP_883801.1 118466135 4527901 complement(4803405..4803830) 1 NC_008595.1 hypothetical protein 4803830 4527901 MAV_4673 Mycobacterium avium 104 hypothetical protein YP_883801.1 4803405 R 243243 CDS YP_883802.1 118462747 4527837 complement(4803835..4804098) 1 NC_008595.1 hypothetical protein 4804098 4527837 MAV_4674 Mycobacterium avium 104 hypothetical protein YP_883802.1 4803835 R 243243 CDS YP_883803.1 118463469 4525522 complement(4804211..4804828) 1 NC_008595.1 heparin binding hemagglutinin hbha 4804828 4525522 MAV_4675 Mycobacterium avium 104 heparin binding hemagglutinin hbha YP_883803.1 4804211 R 243243 CDS YP_883804.1 118463985 4530344 complement(4805033..4805449) 1 NC_008595.1 identified by match to protein family HMM PF01381; XRE family transcriptional regulator 4805449 4530344 MAV_4676 Mycobacterium avium 104 XRE family transcriptional regulator YP_883804.1 4805033 R 243243 CDS YP_883805.1 118464569 4530788 complement(4805533..4806843) 1 NC_008595.1 identified by match to protein family HMM PF04286; hypothetical protein 4806843 4530788 MAV_4677 Mycobacterium avium 104 hypothetical protein YP_883805.1 4805533 R 243243 CDS YP_883806.1 118464651 4528248 4807012..4807686 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4807686 4528248 MAV_4678 Mycobacterium avium 104 TetR family transcriptional regulator YP_883806.1 4807012 D 243243 CDS YP_883807.1 118465677 4525736 4807828..4808688 1 NC_008595.1 identified by match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1 4808688 4525736 MAV_4679 Mycobacterium avium 104 cyclopropane-fatty-acyl-phospholipid synthase 1 YP_883807.1 4807828 D 243243 CDS YP_883808.1 118466363 4529925 complement(4808707..4809576) 1 NC_008595.1 identified by match to protein family HMM PF02353; methoxy mycolic acid synthase 1 4809576 4529925 MAV_4680 Mycobacterium avium 104 methoxy mycolic acid synthase 1 YP_883808.1 4808707 R 243243 CDS YP_883809.1 118466743 4526344 complement(4809655..4810548) 1 NC_008595.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 4810548 4526344 MAV_4681 Mycobacterium avium 104 3-hydroxybutyryl-CoA dehydrogenase YP_883809.1 4809655 R 243243 CDS YP_883810.1 118462260 4526403 complement(4810799..4812085) 1 NC_008595.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 4812085 aceA 4526403 aceA Mycobacterium avium 104 isocitrate lyase YP_883810.1 4810799 R 243243 CDS YP_883811.1 118464914 4530749 complement(4812354..4813130) 1 NC_008595.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase 4813130 4530749 MAV_4683 Mycobacterium avium 104 acyl-ACP thioesterase YP_883811.1 4812354 R 243243 CDS YP_883812.1 118465480 4527233 4813310..4814734 1 NC_008595.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114; DNA-binding protein 4814734 4527233 MAV_4684 Mycobacterium avium 104 DNA-binding protein YP_883812.1 4813310 D 243243 CDS YP_883813.1 118465013 4530062 4814731..4815288 1 NC_008595.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; hypothetical protein 4815288 pcaC 4530062 pcaC Mycobacterium avium 104 hypothetical protein YP_883813.1 4814731 D 243243 CDS YP_883814.1 118467202 4528436 complement(4815296..4815577) 1 NC_008595.1 hypothetical protein 4815577 4528436 MAV_4686 Mycobacterium avium 104 hypothetical protein YP_883814.1 4815296 R 243243 CDS YP_883815.1 118466092 4527721 complement(4815588..4816985) 1 NC_008595.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; dihydrolipoamide dehydrogenase 4816985 lpdA 4527721 lpdA Mycobacterium avium 104 dihydrolipoamide dehydrogenase YP_883815.1 4815588 R 243243 CDS YP_883816.1 118463500 4529079 complement(4817074..4817637) 1 NC_008595.1 hypothetical protein 4817637 4529079 MAV_4688 Mycobacterium avium 104 hypothetical protein YP_883816.1 4817074 R 243243 CDS YP_883817.1 118462749 4527839 complement(4817630..4817908) 1 NC_008595.1 hypothetical protein 4817908 4527839 MAV_4689 Mycobacterium avium 104 hypothetical protein YP_883817.1 4817630 R 243243 CDS YP_883818.1 118464641 4528976 complement(4817937..4818419) 1 NC_008595.1 identified by match to protein family HMM PF05610; hypothetical protein 4818419 4528976 MAV_4690 Mycobacterium avium 104 hypothetical protein YP_883818.1 4817937 R 243243 CDS YP_883819.1 118463923 4528103 complement(4818420..4819943) 1 NC_008595.1 identified by match to protein family HMM PF00171; eptc-inducible aldehyde dehydrogenase 4819943 4528103 MAV_4691 Mycobacterium avium 104 eptc-inducible aldehyde dehydrogenase YP_883819.1 4818420 R 243243 CDS YP_883820.1 118466972 4530371 4822059..4822367 1 NC_008595.1 hypothetical protein 4822367 4530371 MAV_4693 Mycobacterium avium 104 hypothetical protein YP_883820.1 4822059 D 243243 CDS YP_883821.1 118466081 4527349 4822377..4823288 1 NC_008595.1 catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 4823288 4527349 MAV_4694 Mycobacterium avium 104 enoyl-CoA hydratase YP_883821.1 4822377 D 243243 CDS YP_883822.1 118463222 4528796 4823450..4823818 1 NC_008595.1 hypothetical protein 4823818 4528796 MAV_4695 Mycobacterium avium 104 hypothetical protein YP_883822.1 4823450 D 243243 CDS YP_883823.1 118462678 4530605 complement(4823844..4826774) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL4 protein 4826774 4530605 MAV_4696 Mycobacterium avium 104 MmpL4 protein YP_883823.1 4823844 R 243243 CDS YP_883824.1 118465323 4526519 complement(4826771..4827319) 1 NC_008595.1 identified by match to protein family HMM PF05423; membrane protein 4827319 4526519 MAV_4697 Mycobacterium avium 104 membrane protein YP_883824.1 4826771 R 243243 CDS YP_883825.1 118464786 4526710 complement(4827342..4827944) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4827944 4526710 MAV_4698 Mycobacterium avium 104 TetR family transcriptional regulator YP_883825.1 4827342 R 243243 CDS YP_883826.1 118465931 4528490 4828108..4829838 1 NC_008595.1 identified by match to protein family HMM PF02683; DipZ protein 4829838 4528490 MAV_4700 Mycobacterium avium 104 DipZ protein YP_883826.1 4828108 D 243243 CDS YP_883827.1 118465487 4527240 complement(4829825..4830673) 1 NC_008595.1 hypothetical protein 4830673 4527240 MAV_4699 Mycobacterium avium 104 hypothetical protein YP_883827.1 4829825 R 243243 CDS YP_883828.1 118463597 4527544 complement(4830684..4831199) 1 NC_008595.1 hypothetical protein 4831199 4527544 MAV_4701 Mycobacterium avium 104 hypothetical protein YP_883828.1 4830684 R 243243 CDS YP_883829.1 118464020 4528816 complement(4831210..4831575) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 4831575 4528816 MAV_4702 Mycobacterium avium 104 glyoxalase YP_883829.1 4831210 R 243243 CDS YP_883830.1 118462929 4526020 4831623..4833353 1 NC_008595.1 identified by match to protein family HMM PF07908; match to protein family HMM PF07969; amidohydrolase 4833353 4526020 MAV_4703 Mycobacterium avium 104 amidohydrolase YP_883830.1 4831623 D 243243 CDS YP_883831.1 118462388 4525931 4833391..4834035 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4834035 4525931 MAV_4704 Mycobacterium avium 104 PPE family protein YP_883831.1 4833391 D 243243 CDS YP_883832.1 118464484 4528858 4834063..4834455 1 NC_008595.1 hypothetical protein 4834455 4528858 MAV_4705 Mycobacterium avium 104 hypothetical protein YP_883832.1 4834063 D 243243 CDS YP_883833.1 118463248 4525784 complement(4834724..4835605) 1 NC_008595.1 hypothetical protein 4835605 4525784 MAV_4706 Mycobacterium avium 104 hypothetical protein YP_883833.1 4834724 R 243243 CDS YP_883834.1 118465277 4527298 complement(4835762..4837387) 1 NC_008595.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4837387 groEL 4527298 groEL Mycobacterium avium 104 chaperonin GroEL YP_883834.1 4835762 R 243243 CDS YP_883835.1 118464660 4528257 complement(4837582..4838274) 1 NC_008595.1 identified by match to protein family HMM PF00557; aminopeptidase 4838274 4528257 MAV_4708 Mycobacterium avium 104 aminopeptidase YP_883835.1 4837582 R 243243 CDS YP_883836.1 118462663 4529091 4838306..4838800 1 NC_008595.1 identified by match to protein family HMM PF07883; cupin domain-containing protein 4838800 4529091 MAV_4709 Mycobacterium avium 104 cupin domain-containing protein YP_883836.1 4838306 D 243243 CDS YP_883837.1 118464304 4526634 4838832..4839770 1 NC_008595.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 4839770 4526634 MAV_4710 Mycobacterium avium 104 short chain dehydrogenase YP_883837.1 4838832 D 243243 CDS YP_883838.1 118464255 4527440 4839776..4840990 1 NC_008595.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein MoeA 4840990 4527440 MAV_4711 Mycobacterium avium 104 molybdopterin biosynthesis protein MoeA YP_883838.1 4839776 D 243243 CDS YP_883839.1 118467252 4526087 complement(4840997..4842208) 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 4842208 4526087 MAV_4712 Mycobacterium avium 104 transporter, major facilitator family protein YP_883839.1 4840997 R 243243 CDS YP_883840.1 118465442 4527311 4842229..4842951 1 NC_008595.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 4842951 psd 4527311 psd Mycobacterium avium 104 phosphatidylserine decarboxylase YP_883840.1 4842229 D 243243 CDS YP_883841.1 118463227 4528801 4842948..4843811 1 NC_008595.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 4843811 4528801 MAV_4714 Mycobacterium avium 104 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_883841.1 4842948 D 243243 CDS YP_883842.1 118464442 4525973 4843808..4845976 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02359; match to protein family HMM PF07728; cell division protein 48 4845976 4525973 MAV_4716 Mycobacterium avium 104 cell division protein 48 YP_883842.1 4843808 D 243243 CDS YP_883843.1 118466272 4527824 complement(4845950..4846516) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4846516 4527824 MAV_4715 Mycobacterium avium 104 TetR family transcriptional regulator YP_883843.1 4845950 R 243243 CDS YP_883844.1 118467115 4526141 4846568..4847350 1 NC_008595.1 hypothetical protein 4847350 4526141 MAV_4718 Mycobacterium avium 104 hypothetical protein YP_883844.1 4846568 D 243243 CDS YP_883845.1 118462242 4526927 complement(4847304..4848122) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 4848122 4526927 MAV_4717 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_883845.1 4847304 R 243243 CDS YP_883846.1 118465453 4526221 complement(4848119..4849141) 1 NC_008595.1 hypothetical protein 4849141 4526221 MAV_4719 Mycobacterium avium 104 hypothetical protein YP_883846.1 4848119 R 243243 CDS YP_883847.1 118463030 4528871 complement(4849164..4849805) 1 NC_008595.1 identified by match to protein family HMM PF02190; ATP-dependent protease La 4849805 4528871 MAV_4720 Mycobacterium avium 104 ATP-dependent protease La YP_883847.1 4849164 R 243243 CDS YP_883848.1 118462492 4530688 complement(4849805..4850944) 1 NC_008595.1 ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase 4850944 4530688 MAV_4721 Mycobacterium avium 104 carboxylate-amine ligase YP_883848.1 4849805 R 243243 CDS YP_883849.1 118466410 4526253 complement(4850925..4851608) 1 NC_008595.1 identified by similarity to SP:P53635; match to protein family HMM PF00080; superoxide dismutase, Cu-Zn 4851608 sodC 4526253 sodC Mycobacterium avium 104 superoxide dismutase, Cu-Zn YP_883849.1 4850925 R 243243 CDS YP_883850.1 118463237 4525773 complement(4851639..4852070) 1 NC_008595.1 hypothetical protein 4852070 4525773 MAV_4723 Mycobacterium avium 104 hypothetical protein YP_883850.1 4851639 R 243243 CDS YP_883851.1 118465930 4528489 complement(4852135..4852443) 1 NC_008595.1 hypothetical protein 4852443 4528489 MAV_4724 Mycobacterium avium 104 hypothetical protein YP_883851.1 4852135 R 243243 CDS YP_883852.1 118465399 4525659 4852685..4853218 1 NC_008595.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4853218 def 4525659 def Mycobacterium avium 104 peptide deformylase YP_883852.1 4852685 D 243243 CDS YP_883853.1 118464163 4526473 4853218..4854021 1 NC_008595.1 hypothetical protein 4854021 4526473 MAV_4726 Mycobacterium avium 104 hypothetical protein YP_883853.1 4853218 D 243243 CDS YP_883854.1 118464012 4529274 4854032..4854850 1 NC_008595.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633; exodeoxyribonuclease III 4854850 xth 4529274 xth Mycobacterium avium 104 exodeoxyribonuclease III YP_883854.1 4854032 D 243243 CDS YP_883855.1 118464309 4526639 4855048..4855467 1 NC_008595.1 hypothetical protein 4855467 4526639 MAV_4728 Mycobacterium avium 104 hypothetical protein YP_883855.1 4855048 D 243243 CDS YP_883856.1 118466971 4530370 complement(4855469..4855663) 1 NC_008595.1 hypothetical protein 4855663 4530370 MAV_4729 Mycobacterium avium 104 hypothetical protein YP_883856.1 4855469 R 243243 CDS YP_883857.1 118465315 4526569 4855733..4856011 1 NC_008595.1 hypothetical protein 4856011 4526569 MAV_4730 Mycobacterium avium 104 hypothetical protein YP_883857.1 4855733 D 243243 CDS YP_883858.1 118465494 4526790 4856213..4857835 1 NC_008595.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4857835 thiC 4526790 thiC Mycobacterium avium 104 thiamine biosynthesis protein ThiC YP_883858.1 4856213 D 243243 CDS YP_883859.1 118463606 4527553 4857832..4858680 1 NC_008595.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 4858680 thiD 4527553 thiD Mycobacterium avium 104 phosphomethylpyrimidine kinase YP_883859.1 4857832 D 243243 CDS YP_883860.1 118464327 4529832 4858677..4859300 1 NC_008595.1 hypothetical protein 4859300 4529832 MAV_4733 Mycobacterium avium 104 hypothetical protein YP_883860.1 4858677 D 243243 CDS YP_883861.1 118462520 4527663 4859347..4859781 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 4859781 4527663 MAV_4734 Mycobacterium avium 104 MarR family transcriptional regulator YP_883861.1 4859347 D 243243 CDS YP_883862.1 118462579 4530199 4859798..4860673 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 4860673 4530199 MAV_4735 Mycobacterium avium 104 hypothetical protein YP_883862.1 4859798 D 243243 CDS YP_883863.1 118464796 4526720 complement(4860690..4862105) 1 NC_008595.1 LpqM protein 4862105 4526720 MAV_4736 Mycobacterium avium 104 LpqM protein YP_883863.1 4860690 R 243243 CDS YP_883864.1 118464904 4530739 complement(4862250..4863722) 1 NC_008595.1 identified by match to protein family HMM PF02225; match to protein family HMM PF04389; peptidase, M28 family protein 4863722 4530739 MAV_4737 Mycobacterium avium 104 peptidase, M28 family protein YP_883864.1 4862250 R 243243 CDS YP_883865.1 118463079 4527578 complement(4863719..4865215) 1 NC_008595.1 identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389; peptidase, M28 family protein 4865215 4527578 MAV_4738 Mycobacterium avium 104 peptidase, M28 family protein YP_883865.1 4863719 R 243243 CDS YP_883866.1 118463603 4527550 complement(4865269..4865694) 1 NC_008595.1 hypothetical protein 4865694 4527550 MAV_4739 Mycobacterium avium 104 hypothetical protein YP_883866.1 4865269 R 243243 CDS YP_883867.1 118466602 4529368 complement(4865714..4866046) 1 NC_008595.1 hypothetical protein 4866046 4529368 MAV_4740 Mycobacterium avium 104 hypothetical protein YP_883867.1 4865714 R 243243 CDS YP_883868.1 118464168 4526478 4866381..4866911 1 NC_008595.1 hypothetical protein 4866911 4526478 MAV_4741 Mycobacterium avium 104 hypothetical protein YP_883868.1 4866381 D 243243 CDS YP_883869.1 118466015 4529901 4866965..4867486 1 NC_008595.1 hypothetical protein 4867486 4529901 MAV_4742 Mycobacterium avium 104 hypothetical protein YP_883869.1 4866965 D 243243 CDS YP_883870.1 118463051 4528330 complement(4867490..4868257) 1 NC_008595.1 identified by match to protein family HMM PF00657; hypothetical protein 4868257 4528330 MAV_4743 Mycobacterium avium 104 hypothetical protein YP_883870.1 4867490 R 243243 CDS YP_883871.1 118463665 4525957 complement(4868254..4869012) 1 NC_008595.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4869012 thiG 4525957 thiG Mycobacterium avium 104 thiazole synthase YP_883871.1 4868254 R 243243 CDS YP_883872.1 118465936 4528495 complement(4869005..4869202) 1 NC_008595.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4869202 thiS 4528495 thiS Mycobacterium avium 104 sulfur carrier protein ThiS YP_883872.1 4869005 R 243243 CDS YP_883873.1 118465562 4526748 complement(4869252..4870268) 1 NC_008595.1 identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352; glycine oxidase ThiO 4870268 thiO 4526748 thiO Mycobacterium avium 104 glycine oxidase ThiO YP_883873.1 4869252 R 243243 CDS YP_883874.1 118465379 4529670 4870409..4871080 1 NC_008595.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 4871080 thiE 4529670 thiE Mycobacterium avium 104 thiamine-phosphate pyrophosphorylase YP_883874.1 4870409 D 243243 CDS YP_883875.1 118464530 4529450 complement(4871052..4871693) 1 NC_008595.1 identified by match to protein family HMM PF00293; hydrolase, NUDIX family protein 4871693 4529450 MAV_4747 Mycobacterium avium 104 hydrolase, NUDIX family protein YP_883875.1 4871052 R 243243 CDS YP_883876.1 118464911 4530746 4871844..4873163 1 NC_008595.1 hypothetical protein 4873163 4530746 MAV_4749 Mycobacterium avium 104 hypothetical protein YP_883876.1 4871844 D 243243 CDS YP_883877.1 118465451 4526219 4873136..4874140 1 NC_008595.1 identified by match to protein family HMM PF00497; extracellular solute-binding protein, family protein 3 4874140 4526219 MAV_4750 Mycobacterium avium 104 extracellular solute-binding protein, family protein 3 YP_883877.1 4873136 D 243243 CDS YP_883878.1 118463342 4529212 4874140..4876431 1 NC_008595.1 identified by match to protein family HMM PF00069; serine/threonine protein kinase 4876431 4529212 MAV_4751 Mycobacterium avium 104 serine/threonine protein kinase YP_883878.1 4874140 D 243243 CDS YP_883879.1 118466530 4527203 4876491..4876604 1 NC_008595.1 hypothetical protein 4876604 4527203 MAV_4753 Mycobacterium avium 104 hypothetical protein YP_883879.1 4876491 D 243243 CDS YP_883880.1 118463624 4527328 complement(4876596..4877459) 1 NC_008595.1 hypothetical protein 4877459 4527328 MAV_4752 Mycobacterium avium 104 hypothetical protein YP_883880.1 4876596 R 243243 CDS YP_883881.1 118467105 4526367 complement(4877520..4878152) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4878152 4526367 MAV_4754 Mycobacterium avium 104 TetR family transcriptional regulator YP_883881.1 4877520 R 243243 CDS YP_883882.1 118462785 4525753 complement(4878158..4880971) 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; MmpL4 protein 4880971 4525753 MAV_4755 Mycobacterium avium 104 MmpL4 protein YP_883882.1 4878158 R 243243 CDS YP_883883.1 118464149 4526458 complement(4881022..4881432) 1 NC_008595.1 identified by match to protein family HMM PF05423; membrane protein 4881432 4526458 MAV_4756 Mycobacterium avium 104 membrane protein YP_883883.1 4881022 R 243243 CDS YP_883884.1 118464493 4525536 4881628..4883010 1 NC_008595.1 hypothetical protein 4883010 4525536 MAV_4757 Mycobacterium avium 104 hypothetical protein YP_883884.1 4881628 D 243243 CDS YP_883885.1 118463708 4530595 4883007..4884191 1 NC_008595.1 identified by match to protein family HMM PF07394; match to protein family HMM TIGR01409; hypothetical protein 4884191 4530595 MAV_4759 Mycobacterium avium 104 hypothetical protein YP_883885.1 4883007 D 243243 CDS YP_883886.1 118462665 4529093 complement(4884180..4885343) 1 NC_008595.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 4885343 ackA 4529093 ackA Mycobacterium avium 104 acetate kinase YP_883886.1 4884180 R 243243 CDS YP_883887.1 118466844 4526953 complement(4885333..4887420) 1 NC_008595.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 4887420 4526953 MAV_4760 Mycobacterium avium 104 phosphate acetyltransferase YP_883887.1 4885333 R 243243 CDS YP_883888.1 118466155 4528777 complement(4887413..4888423) 1 NC_008595.1 identified by match to protein family HMM PF00296; F420-dependent glucose-6-phosphate dehydrogenase 4888423 4528777 MAV_4761 Mycobacterium avium 104 F420-dependent glucose-6-phosphate dehydrogenase YP_883888.1 4887413 R 243243 CDS YP_883889.1 118463433 4528312 4888459..4889202 1 NC_008595.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 4889202 4528312 MAV_4762 Mycobacterium avium 104 metallo-beta-lactamase YP_883889.1 4888459 D 243243 CDS YP_883890.1 118462878 4527106 complement(4889301..4889819) 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 4889819 4527106 MAV_4763 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_883890.1 4889301 R 243243 CDS YP_883891.1 118463617 4527321 complement(4889828..4890718) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 4890718 4527321 MAV_4764 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883891.1 4889828 R 243243 CDS YP_883892.1 118464541 4530411 complement(4890738..4891109) 1 NC_008595.1 hypothetical protein 4891109 4530411 MAV_4765 Mycobacterium avium 104 hypothetical protein YP_883892.1 4890738 R 243243 CDS YP_883893.1 118462238 4526923 4891181..4891927 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase/reductase SDR 4891927 4526923 MAV_4766 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_883893.1 4891181 D 243243 CDS YP_883894.1 118464253 4527438 4891933..4893129 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 4893129 4527438 MAV_4767 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_883894.1 4891933 D 243243 CDS YP_883895.1 118463794 4525875 4893146..4894294 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; long-chain specific acyl-CoA dehydrogenase 4894294 4525875 MAV_4768 Mycobacterium avium 104 long-chain specific acyl-CoA dehydrogenase YP_883895.1 4893146 D 243243 CDS YP_883896.1 118466950 4530262 4894299..4894961 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4894961 4530262 MAV_4769 Mycobacterium avium 104 TetR family transcriptional regulator YP_883896.1 4894299 D 243243 CDS YP_883897.1 118462232 4525569 4894966..4895586 1 NC_008595.1 hypothetical protein 4895586 4525569 MAV_4770 Mycobacterium avium 104 hypothetical protein YP_883897.1 4894966 D 243243 CDS YP_883898.1 118462915 4526004 complement(4896101..4896451) 1 NC_008595.1 hypothetical protein 4896451 4526004 MAV_4771 Mycobacterium avium 104 hypothetical protein YP_883898.1 4896101 R 243243 CDS YP_883899.1 118464827 4529729 4896440..4897831 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; DoxD family protein/pyridine nucleotide-disulfide oxidoreductase 4897831 4529729 MAV_4772 Mycobacterium avium 104 DoxD family protein/pyridine nucleotide-disulfide oxidoreductase YP_883899.1 4896440 D 243243 CDS YP_883900.1 118465525 4528943 complement(4897837..4899063) 1 NC_008595.1 identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01325; O-succinylhomoserine sulfhydrylase 4899063 metZ 4528943 metZ Mycobacterium avium 104 O-succinylhomoserine sulfhydrylase YP_883900.1 4897837 R 243243 CDS YP_883901.1 118464101 4525862 complement(4899069..4899509) 1 NC_008595.1 hypothetical protein 4899509 4525862 MAV_4774 Mycobacterium avium 104 hypothetical protein YP_883901.1 4899069 R 243243 CDS YP_883902.1 118464706 4527895 complement(4899595..4900845) 1 NC_008595.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 4900845 purT 4527895 purT Mycobacterium avium 104 phosphoribosylglycinamide formyltransferase 2 YP_883902.1 4899595 R 243243 CDS YP_883903.1 118465301 4526555 complement(4900911..4901549) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 4901549 4526555 MAV_4776 Mycobacterium avium 104 thioesterase YP_883903.1 4900911 R 243243 CDS YP_883904.1 118465862 4527504 complement(4901546..4902844) 1 NC_008595.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4902844 purA 4527504 purA Mycobacterium avium 104 adenylosuccinate synthetase YP_883904.1 4901546 R 243243 CDS YP_883905.1 118463647 4528549 complement(4902952..4903893) 1 NC_008595.1 identified by match to protein family HMM PF00300; pe_pgrs family protein 4903893 4528549 MAV_4778 Mycobacterium avium 104 pe_pgrs family protein YP_883905.1 4902952 R 243243 CDS YP_883906.1 118462323 4529641 4903903..4904031 1 NC_008595.1 hypothetical protein 4904031 4529641 MAV_4779 Mycobacterium avium 104 hypothetical protein YP_883906.1 4903903 D 243243 CDS YP_883907.1 118465815 4525918 4904190..4904840 1 NC_008595.1 hypothetical protein 4904840 4525918 MAV_4780 Mycobacterium avium 104 hypothetical protein YP_883907.1 4904190 D 243243 CDS YP_883908.1 118466371 4529933 4904850..4905632 1 NC_008595.1 identified by match to protein family HMM PF02163; peptidase, M50 family protein 4905632 4529933 MAV_4781 Mycobacterium avium 104 peptidase, M50 family protein YP_883908.1 4904850 D 243243 CDS YP_883909.1 118465583 4527130 4905673..4906569 1 NC_008595.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cobalt-zinc-cadmium resistance protein 4906569 4527130 MAV_4782 Mycobacterium avium 104 cobalt-zinc-cadmium resistance protein YP_883909.1 4905673 D 243243 CDS YP_883910.1 118464839 4527955 complement(4906576..4906989) 1 NC_008595.1 hypothetical protein 4906989 4527955 MAV_4783 Mycobacterium avium 104 hypothetical protein YP_883910.1 4906576 R 243243 CDS YP_883911.1 118467008 4529478 4907113..4907991 1 NC_008595.1 hypothetical protein 4907991 4529478 MAV_4784 Mycobacterium avium 104 hypothetical protein YP_883911.1 4907113 D 243243 CDS YP_883912.1 118466316 4528358 4908029..4908721 1 NC_008595.1 membrane protein DedA family protein 4908721 4528358 MAV_4785 Mycobacterium avium 104 membrane protein DedA family protein YP_883912.1 4908029 D 243243 CDS YP_883913.1 118463942 4526594 complement(4908729..4910078) 1 NC_008595.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428; match to protein family HMM TIGR02429; succinyl-CoA:3-ketoacid-coenzyme A transferase 1 4910078 4526594 MAV_4786 Mycobacterium avium 104 succinyl-CoA:3-ketoacid-coenzyme A transferase 1 YP_883913.1 4908729 R 243243 CDS YP_883914.1 118464777 4529132 complement(4910075..4911214) 1 NC_008595.1 hypothetical protein 4911214 4529132 MAV_4787 Mycobacterium avium 104 hypothetical protein YP_883914.1 4910075 R 243243 CDS YP_883915.1 118462459 4525632 complement(4911327..4911971) 1 NC_008595.1 identified by match to protein family HMM PF00588; spou rRNA methylase 4911971 4525632 MAV_4788 Mycobacterium avium 104 spou rRNA methylase YP_883915.1 4911327 R 243243 CDS YP_883916.1 118463170 4529872 complement(4911968..4912828) 1 NC_008595.1 hypothetical protein 4912828 4529872 MAV_4789 Mycobacterium avium 104 hypothetical protein YP_883916.1 4911968 R 243243 CDS YP_883917.1 118466376 4529938 complement(4912880..4913419) 1 NC_008595.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4913419 pyrE 4529938 pyrE Mycobacterium avium 104 orotate phosphoribosyltransferase YP_883917.1 4912880 R 243243 CDS YP_883918.1 118463232 4528806 complement(4913406..4914179) 1 NC_008595.1 identified by match to protein family HMM PF00106; dehydrogenase 4914179 4528806 MAV_4791 Mycobacterium avium 104 dehydrogenase YP_883918.1 4913406 R 243243 CDS YP_883919.1 118464891 4529620 complement(4914236..4915108) 1 NC_008595.1 hypothetical protein 4915108 4529620 MAV_4792 Mycobacterium avium 104 hypothetical protein YP_883919.1 4914236 R 243243 CDS YP_883920.1 118466771 4530766 complement(4915249..4917795) 1 NC_008595.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; chaperone ClpB 4917795 4530766 MAV_4793 Mycobacterium avium 104 chaperone ClpB YP_883920.1 4915249 R 243243 CDS YP_883921.1 118464376 4528265 4917921..4918415 1 NC_008595.1 hypothetical protein 4918415 4528265 MAV_4794 Mycobacterium avium 104 hypothetical protein YP_883921.1 4917921 D 243243 CDS YP_883922.1 118464785 4526709 4918448..4919629 1 NC_008595.1 identified by match to protein family HMM PF00042; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase FAD-binding subunit 4919629 4526709 MAV_4795 Mycobacterium avium 104 oxidoreductase FAD-binding subunit YP_883922.1 4918448 D 243243 CDS YP_883923.1 118464042 4529014 complement(4920515..4923574) 1 NC_008595.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase domain-containing protein 4923574 4529014 MAV_4796 Mycobacterium avium 104 FAD dependent oxidoreductase domain-containing protein YP_883923.1 4920515 R 243243 CDS YP_883924.1 118467044 4526500 complement(4923571..4923972) 1 NC_008595.1 hypothetical protein 4923972 4526500 MAV_4798 Mycobacterium avium 104 hypothetical protein YP_883924.1 4923571 R 243243 CDS YP_883925.1 118465819 4525922 complement(4923965..4924987) 1 NC_008595.1 hypothetical protein 4924987 4525922 MAV_4799 Mycobacterium avium 104 hypothetical protein YP_883925.1 4923965 R 243243 CDS YP_883926.1 118464332 4529837 complement(4924984..4925253) 1 NC_008595.1 hypothetical protein 4925253 4529837 MAV_4800 Mycobacterium avium 104 hypothetical protein YP_883926.1 4924984 R 243243 CDS YP_883927.1 118462475 4528729 complement(4925250..4925708) 1 NC_008595.1 hypothetical protein 4925708 4528729 MAV_4801 Mycobacterium avium 104 hypothetical protein YP_883927.1 4925250 R 243243 CDS YP_883928.1 118462300 4525645 complement(4925705..4926892) 1 NC_008595.1 identified by match to protein family HMM PF00348; polyprenyl synthetase 4926892 4525645 MAV_4802 Mycobacterium avium 104 polyprenyl synthetase YP_883928.1 4925705 R 243243 CDS YP_883929.1 118465314 4526568 complement(4926889..4927662) 1 NC_008595.1 hypothetical protein 4927662 4526568 MAV_4803 Mycobacterium avium 104 hypothetical protein YP_883929.1 4926889 R 243243 CDS YP_883930.1 118466598 4529364 complement(4927757..4932055) 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF01590; match to protein family HMM PF07719; GAF domain-containing protein 4932055 4529364 MAV_4804 Mycobacterium avium 104 GAF domain-containing protein YP_883930.1 4927757 R 243243 CDS YP_883931.1 118466080 4527348 complement(4932198..4932593) 1 NC_008595.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 4932593 4527348 MAV_4805 Mycobacterium avium 104 MerR family transcriptional regulator YP_883931.1 4932198 R 243243 CDS YP_883932.1 118466620 4526858 complement(4932593..4933771) 1 NC_008595.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 4933771 dnaJ 4526858 dnaJ Mycobacterium avium 104 chaperone protein DnaJ YP_883932.1 4932593 R 243243 CDS YP_883933.1 118465887 4527921 complement(4933832..4934515) 1 NC_008595.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 4934515 4527921 MAV_4807 Mycobacterium avium 104 heat shock protein GrpE YP_883933.1 4933832 R 243243 CDS YP_883934.1 118465208 4529845 complement(4934512..4936383) 1 NC_008595.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 4936383 dnaK 4529845 dnaK Mycobacterium avium 104 molecular chaperone DnaK YP_883934.1 4934512 R 243243 CDS YP_883935.1 118466151 4528773 4936626..4937225 1 NC_008595.1 hypothetical protein 4937225 4528773 MAV_4809 Mycobacterium avium 104 hypothetical protein YP_883935.1 4936626 D 243243 CDS YP_883936.1 118466840 4526949 4937210..4937872 1 NC_008595.1 hypothetical protein 4937872 4526949 MAV_4810 Mycobacterium avium 104 hypothetical protein YP_883936.1 4937210 D 243243 CDS YP_883937.1 118465012 4526278 4938008..4938592 1 NC_008595.1 LpqJ protein 4938592 4526278 MAV_4811 Mycobacterium avium 104 LpqJ protein YP_883937.1 4938008 D 243243 CDS YP_883938.1 118466772 4530767 4941384..4942004 1 NC_008595.1 hypothetical protein 4942004 4530767 MAV_4813 Mycobacterium avium 104 hypothetical protein YP_883938.1 4941384 D 243243 CDS YP_883939.1 118464934 4528574 complement(4942305..4943654) 1 NC_008595.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; metabolite/sugar transport protein 4943654 4528574 MAV_4814 Mycobacterium avium 104 metabolite/sugar transport protein YP_883939.1 4942305 R 243243 CDS YP_883940.1 118463490 4529069 4944132..4944755 1 NC_008595.1 hypothetical protein 4944755 4529069 MAV_4815 Mycobacterium avium 104 hypothetical protein YP_883940.1 4944132 D 243243 CDS YP_883941.1 118466383 4526184 4944810..4946507 1 NC_008595.1 hypothetical protein 4946507 4526184 MAV_4816 Mycobacterium avium 104 hypothetical protein YP_883941.1 4944810 D 243243 CDS YP_883942.1 118462585 4530206 4946734..4949661 1 NC_008595.1 identified by match to protein family HMM PF00037; match to protein family HMM PF02754; ferredoxin, 4Fe-4S 4949661 4530206 MAV_4817 Mycobacterium avium 104 ferredoxin, 4Fe-4S YP_883942.1 4946734 D 243243 CDS YP_883943.1 118464627 4526784 4949742..4950986 1 NC_008595.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 4950986 4526784 MAV_4818 Mycobacterium avium 104 aminotransferase AlaT YP_883943.1 4949742 D 243243 CDS YP_883944.1 118466644 4528082 4951019..4952284 1 NC_008595.1 identified by match to protein family HMM PF07907; hypothetical protein 4952284 4528082 MAV_4819 Mycobacterium avium 104 hypothetical protein YP_883944.1 4951019 D 243243 CDS YP_883945.1 118466112 4529745 complement(4952336..4953211) 1 NC_008595.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 4953211 rfbA 4529745 rfbA Mycobacterium avium 104 glucose-1-phosphate thymidylyltransferase YP_883945.1 4952336 R 243243 CDS YP_883946.1 118462935 4530219 complement(4953239..4953613) 1 NC_008595.1 hypothetical protein 4953613 4530219 MAV_4821 Mycobacterium avium 104 hypothetical protein YP_883946.1 4953239 R 243243 CDS YP_883947.1 118463349 4529883 complement(4953643..4954437) 1 NC_008595.1 identified by match to protein family HMM PF07398; match to protein family HMM TIGR03083; hypothetical protein 4954437 4529883 MAV_4822 Mycobacterium avium 104 hypothetical protein YP_883947.1 4953643 R 243243 CDS YP_883948.1 118464251 4527436 complement(4954494..4955807) 1 NC_008595.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 4955807 4527436 MAV_4823 Mycobacterium avium 104 UDP-glucose 6-dehydrogenase YP_883948.1 4954494 R 243243 CDS YP_883949.1 118462565 4528624 complement(4955958..4957406) 1 NC_008595.1 hypothetical protein 4957406 4528624 MAV_4824 Mycobacterium avium 104 hypothetical protein YP_883949.1 4955958 R 243243 CDS YP_883950.1 118463376 4528954 complement(4957584..4958702) 1 NC_008595.1 hypothetical protein 4958702 4528954 MAV_4825 Mycobacterium avium 104 hypothetical protein YP_883950.1 4957584 R 243243 CDS YP_883951.1 118462913 4528176 complement(4958875..4960347) 1 NC_008595.1 hypothetical protein 4960347 4528176 MAV_4826 Mycobacterium avium 104 hypothetical protein YP_883951.1 4958875 R 243243 CDS YP_883952.1 118464492 4528866 complement(4960593..4962527) 1 NC_008595.1 hypothetical protein 4962527 4528866 MAV_4827 Mycobacterium avium 104 hypothetical protein YP_883952.1 4960593 R 243243 CDS YP_883953.1 118464071 4528384 complement(4962634..4963206) 1 NC_008595.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 4963206 dcd 4528384 dcd Mycobacterium avium 104 deoxycytidine triphosphate deaminase YP_883953.1 4962634 R 243243 CDS YP_883954.1 118465825 4525497 complement(4963236..4963694) 1 NC_008595.1 hypothetical protein 4963694 4525497 MAV_4829 Mycobacterium avium 104 hypothetical protein YP_883954.1 4963236 R 243243 CDS YP_883955.1 118465742 4525705 4964282..4964599 1 NC_008595.1 hypothetical protein 4964599 4525705 MAV_4831 Mycobacterium avium 104 hypothetical protein YP_883955.1 4964282 D 243243 CDS YP_883956.1 118464199 4529310 4964596..4964886 1 NC_008595.1 hypothetical protein 4964886 4529310 MAV_4832 Mycobacterium avium 104 hypothetical protein YP_883956.1 4964596 D 243243 CDS YP_883957.1 118466051 4528059 complement(4964908..4965117) 1 NC_008595.1 hypothetical protein 4965117 4528059 MAV_4833 Mycobacterium avium 104 hypothetical protein YP_883957.1 4964908 R 243243 CDS YP_883958.1 118466895 4528409 4965697..4966461 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 4966461 4528409 MAV_4834 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_883958.1 4965697 D 243243 CDS YP_883959.1 118464932 4528572 complement(4966623..4967165) 1 NC_008595.1 hypothetical protein 4967165 4528572 MAV_4835 Mycobacterium avium 104 hypothetical protein YP_883959.1 4966623 R 243243 CDS YP_883960.1 118462859 4526041 4967508..4967846 1 NC_008595.1 identified by match to protein family HMM PF05305; hypothetical protein 4967846 4526041 MAV_4836 Mycobacterium avium 104 hypothetical protein YP_883960.1 4967508 D 243243 CDS YP_883961.1 118466642 4528080 4968076..4968372 1 NC_008595.1 hypothetical protein 4968372 4528080 MAV_4837 Mycobacterium avium 104 hypothetical protein YP_883961.1 4968076 D 243243 CDS YP_883962.1 118463254 4528119 4968425..4969828 1 NC_008595.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol 2-dehydrogenase 4969828 4528119 MAV_4838 Mycobacterium avium 104 mannitol 2-dehydrogenase YP_883962.1 4968425 D 243243 CDS YP_883963.1 118463748 4528156 4969902..4970684 1 NC_008595.1 hypothetical protein 4970684 4528156 MAV_4840 Mycobacterium avium 104 hypothetical protein YP_883963.1 4969902 D 243243 CDS YP_883964.1 118463847 4529946 complement(4970660..4971331) 1 NC_008595.1 hypothetical protein 4971331 4529946 MAV_4839 Mycobacterium avium 104 hypothetical protein YP_883964.1 4970660 R 243243 CDS YP_883965.1 118465551 4525799 complement(4971392..4972045) 1 NC_008595.1 hypothetical protein 4972045 4525799 MAV_4841 Mycobacterium avium 104 hypothetical protein YP_883965.1 4971392 R 243243 CDS YP_883966.1 118467328 4526966 complement(4972114..4972419) 1 NC_008595.1 hypothetical protein 4972419 4526966 MAV_4842 Mycobacterium avium 104 hypothetical protein YP_883966.1 4972114 R 243243 CDS YP_883967.1 118465904 4528986 4972496..4974016 1 NC_008595.1 hypothetical protein 4974016 4528986 MAV_4843 Mycobacterium avium 104 hypothetical protein YP_883967.1 4972496 D 243243 CDS YP_883968.1 118465182 4528672 complement(4974020..4974841) 1 NC_008595.1 identified by match to protein family HMM PF00722; glycosyl hydrolases family protein 16 4974841 4528672 MAV_4844 Mycobacterium avium 104 glycosyl hydrolases family protein 16 YP_883968.1 4974020 R 243243 CDS YP_883969.1 118463718 4528068 complement(4974960..4975979) 1 NC_008595.1 identified by match to protein family HMM PF00107; oxidoreductase, zinc-binding 4975979 4528068 MAV_4845 Mycobacterium avium 104 oxidoreductase, zinc-binding YP_883969.1 4974960 R 243243 CDS YP_883970.1 118466590 4529356 4976037..4976699 1 NC_008595.1 hypothetical protein 4976699 4529356 MAV_4846 Mycobacterium avium 104 hypothetical protein YP_883970.1 4976037 D 243243 CDS YP_883971.1 118466301 4529548 complement(4976703..4977089) 1 NC_008595.1 hypothetical protein 4977089 4529548 MAV_4847 Mycobacterium avium 104 hypothetical protein YP_883971.1 4976703 R 243243 CDS YP_883972.1 118462981 4527409 complement(4977155..4978543) 1 NC_008595.1 hypothetical protein 4978543 4527409 MAV_4848 Mycobacterium avium 104 hypothetical protein YP_883972.1 4977155 R 243243 CDS YP_883973.1 118465398 4525658 complement(4980816..4982042) 1 NC_008595.1 hypothetical protein 4982042 4525658 MAV_4850 Mycobacterium avium 104 hypothetical protein YP_883973.1 4980816 R 243243 CDS YP_883974.1 118462288 4529293 4982081..4982701 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4982701 4529293 MAV_4851 Mycobacterium avium 104 TetR family transcriptional regulator YP_883974.1 4982081 D 243243 CDS YP_883975.1 118463006 4530636 4982706..4983185 1 NC_008595.1 hypothetical protein 4983185 4530636 MAV_4852 Mycobacterium avium 104 hypothetical protein YP_883975.1 4982706 D 243243 CDS YP_883976.1 118463717 4528067 complement(4983189..4983809) 1 NC_008595.1 hypothetical protein 4983809 4528067 MAV_4853 Mycobacterium avium 104 hypothetical protein YP_883976.1 4983189 R 243243 CDS YP_883977.1 118464453 4525984 complement(4983947..4984591) 1 NC_008595.1 identified by match to protein family HMM PF01569; PAP2 superfamily protein 4984591 4525984 MAV_4854 Mycobacterium avium 104 PAP2 superfamily protein YP_883977.1 4983947 R 243243 CDS YP_883978.1 118464560 4530779 4984671..4985132 1 NC_008595.1 hypothetical protein 4985132 4530779 MAV_4856 Mycobacterium avium 104 hypothetical protein YP_883978.1 4984671 D 243243 CDS YP_883979.1 118464034 4529006 complement(4985116..4985400) 1 NC_008595.1 hypothetical protein 4985400 4529006 MAV_4855 Mycobacterium avium 104 hypothetical protein YP_883979.1 4985116 R 243243 CDS YP_883980.1 118464819 4527638 4985457..4986116 1 NC_008595.1 identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476; cob(II)yrinic acid a,c-diamide reductase 4986116 bluB 4527638 bluB Mycobacterium avium 104 cob(II)yrinic acid a,c-diamide reductase YP_883980.1 4985457 D 243243 CDS YP_883981.1 118465992 4526134 4986186..4987616 1 NC_008595.1 identified by match to protein family HMM PF00884; sulfatase 4987616 4526134 MAV_4858 Mycobacterium avium 104 sulfatase YP_883981.1 4986186 D 243243 CDS YP_883982.1 118463125 4529650 complement(4987786..4988568) 1 NC_008595.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 4988568 4529650 MAV_4859 Mycobacterium avium 104 trans-aconitate 2-methyltransferase YP_883982.1 4987786 R 243243 CDS YP_883983.1 118464320 4529825 4988738..4989937 1 NC_008595.1 hypothetical protein 4989937 4529825 MAV_4861 Mycobacterium avium 104 hypothetical protein YP_883983.1 4988738 D 243243 CDS YP_883984.1 118466437 4527110 complement(4989927..4990919) 1 NC_008595.1 hypothetical protein 4990919 4527110 MAV_4860 Mycobacterium avium 104 hypothetical protein YP_883984.1 4989927 R 243243 CDS YP_883985.1 118462463 4528717 complement(4990916..4992322) 1 NC_008595.1 identified by match to protein family HMM PF00082; subtilase 4992322 4528717 MAV_4862 Mycobacterium avium 104 subtilase YP_883985.1 4990916 R 243243 CDS YP_883986.1 118465427 4529976 complement(4992319..4993761) 1 NC_008595.1 identified by match to protein family HMM PF04600; hypothetical protein 4993761 4529976 MAV_4863 Mycobacterium avium 104 hypothetical protein YP_883986.1 4992319 R 243243 CDS YP_883987.1 118465963 4528182 complement(4993823..4994704) 1 NC_008595.1 hypothetical protein 4994704 4528182 MAV_4864 Mycobacterium avium 104 hypothetical protein YP_883987.1 4993823 R 243243 CDS YP_883988.1 118465386 4529678 complement(4994725..4995018) 1 NC_008595.1 low molecular weight protein antigen 7 Cfp7 4995018 4529678 MAV_4865 Mycobacterium avium 104 low molecular weight protein antigen 7 Cfp7 YP_883988.1 4994725 R 243243 CDS YP_883989.1 118465920 4529002 complement(4995056..4995343) 1 NC_008595.1 PE family protein 4995343 4529002 MAV_4866 Mycobacterium avium 104 PE family protein YP_883989.1 4995056 R 243243 CDS YP_883990.1 118466312 4528354 complement(4995413..4996894) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 4996894 4528354 MAV_4867 Mycobacterium avium 104 PPE family protein YP_883990.1 4995413 R 243243 CDS YP_883991.1 118467190 4528424 complement(4996898..4997206) 1 NC_008595.1 identified by match to protein family HMM PF00934; PE family protein 4997206 4528424 MAV_4868 Mycobacterium avium 104 PE family protein YP_883991.1 4996898 R 243243 CDS YP_883992.1 118463197 4527524 complement(5001170..5002804) 1 NC_008595.1 identified by match to protein family HMM PF05108; hypothetical protein 5002804 4527524 MAV_4870 Mycobacterium avium 104 hypothetical protein YP_883992.1 5001170 R 243243 CDS YP_883993.1 118466988 4529515 complement(5002801..5004654) 1 NC_008595.1 identified by match to protein family HMM PF00004; ATPase AAA 5004654 4529515 MAV_4871 Mycobacterium avium 104 ATPase AAA YP_883993.1 5002801 R 243243 CDS YP_883994.1 118465015 4530064 complement(5004984..5006450) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 5006450 4530064 MAV_4872 Mycobacterium avium 104 PPE family protein YP_883994.1 5004984 R 243243 CDS YP_883995.1 118465553 4525802 complement(5006630..5007535) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 5007535 4525802 MAV_4873 Mycobacterium avium 104 methyltransferase, putative, family protein YP_883995.1 5006630 R 243243 CDS YP_883996.1 118464058 4529498 complement(5007662..5008807) 1 NC_008595.1 identified by match to protein family HMM PF07683; CobW/P47K domain-containing protein 5008807 4529498 MAV_4874 Mycobacterium avium 104 CobW/P47K domain-containing protein YP_883996.1 5007662 R 243243 CDS YP_883997.1 118464773 4529128 5008961..5009197 1 NC_008595.1 identified by match to protein family HMM PF00830; match to protein family HMM TIGR00009; ribosomal protein L28 5009197 rpmB 4529128 rpmB Mycobacterium avium 104 ribosomal protein L28 YP_883997.1 5008961 D 243243 CDS YP_883998.2 161579555 4530207 5009197..5009361 1 NC_008595.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 5009361 rpmG 4530207 rpmG Mycobacterium avium 104 50S ribosomal protein L33 YP_883998.2 5009197 D 243243 CDS YP_883999.1 118463285 4530533 complement(5009373..5010110) 1 NC_008595.1 hypothetical protein 5010110 4530533 MAV_4877 Mycobacterium avium 104 hypothetical protein YP_883999.1 5009373 R 243243 CDS YP_884000.1 118464420 4530241 complement(5010110..5011102) 1 NC_008595.1 identified by match to protein family HMM PF03773; permease 5011102 4530241 MAV_4878 Mycobacterium avium 104 permease YP_884000.1 5010110 R 243243 CDS YP_884001.1 118462537 4527680 complement(5011141..5012724) 1 NC_008595.1 identified by match to protein family HMM PF00823; PPE family protein 5012724 4527680 MAV_4879 Mycobacterium avium 104 PPE family protein YP_884001.1 5011141 R 243243 CDS YP_884002.1 118466939 4527774 complement(5012819..5013763) 1 NC_008595.1 hypothetical protein 5013763 4527774 MAV_4880 Mycobacterium avium 104 hypothetical protein YP_884002.1 5012819 R 243243 CDS YP_884003.1 118465132 4529163 5013847..5014509 1 NC_008595.1 FadD27 protein 5014509 4529163 MAV_4882 Mycobacterium avium 104 FadD27 protein YP_884003.1 5013847 D 243243 CDS YP_884004.1 118466003 4528447 complement(5014506..5015858) 1 NC_008595.1 hypothetical protein 5015858 4528447 MAV_4881 Mycobacterium avium 104 hypothetical protein YP_884004.1 5014506 R 243243 CDS YP_884005.1 118463592 4529778 complement(5015861..5017336) 1 NC_008595.1 identified by match to protein family HMM PF00668; condensation domain-containing protein 5017336 4529778 MAV_4883 Mycobacterium avium 104 condensation domain-containing protein YP_884005.1 5015861 R 243243 CDS YP_884006.1 118464155 4526464 complement(5017722..5018270) 1 NC_008595.1 hypothetical protein 5018270 4526464 MAV_4884 Mycobacterium avium 104 hypothetical protein YP_884006.1 5017722 R 243243 CDS YP_884007.1 118462488 4530684 complement(5018296..5018877) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase/bleomycin resistance protein/dioxygenase 5018877 4530684 MAV_4885 Mycobacterium avium 104 glyoxalase/bleomycin resistance protein/dioxygenase YP_884007.1 5018296 R 243243 CDS YP_884008.1 118463028 4528869 5018972..5019628 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5019628 4528869 MAV_4886 Mycobacterium avium 104 TetR family transcriptional regulator YP_884008.1 5018972 D 243243 CDS YP_884009.1 118465409 4525669 5021264..5023060 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5023060 4525669 MAV_4888 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884009.1 5021264 D 243243 CDS YP_884010.1 118464574 4530278 complement(5023197..5023298) 1 NC_008595.1 hypothetical protein 5023298 4530278 MAV_4889 Mycobacterium avium 104 hypothetical protein YP_884010.1 5023197 R 243243 CDS YP_884011.1 118463622 4527326 complement(5024058..5024444) 1 NC_008595.1 hypothetical protein 5024444 4527326 MAV_4890 Mycobacterium avium 104 hypothetical protein YP_884011.1 5024058 R 243243 CDS YP_884012.1 118462477 4528731 complement(5024454..5026139) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 5026139 4528731 MAV_4891 Mycobacterium avium 104 acyl-CoA synthetase YP_884012.1 5024454 R 243243 CDS YP_884013.1 118466745 4526346 5026197..5027477 1 NC_008595.1 hypothetical protein 5027477 4526346 MAV_4893 Mycobacterium avium 104 hypothetical protein YP_884013.1 5026197 D 243243 CDS YP_884014.1 118465101 4529992 complement(5027474..5028865) 1 NC_008595.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite transporter 5028865 narK 4529992 narK Mycobacterium avium 104 nitrite transporter YP_884014.1 5027474 R 243243 CDS YP_884015.1 118464262 4528217 5029115..5029699 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5029699 4528217 MAV_4894 Mycobacterium avium 104 TetR family transcriptional regulator YP_884015.1 5029115 D 243243 CDS YP_884016.1 118464518 4529438 5029811..5030764 1 NC_008595.1 identified by match to protein family HMM PF01497; periplasmic binding protein 5030764 4529438 MAV_4895 Mycobacterium avium 104 periplasmic binding protein YP_884016.1 5029811 D 243243 CDS YP_884017.1 118463109 4527171 5030871..5031539 1 NC_008595.1 identified by match to protein family HMM PF02682; allophanate hydrolase subunit 1 5031539 4527171 MAV_4896 Mycobacterium avium 104 allophanate hydrolase subunit 1 YP_884017.1 5030871 D 243243 CDS YP_884018.1 118467301 4527260 5031559..5032470 1 NC_008595.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; hypothetical protein 5032470 4527260 MAV_4897 Mycobacterium avium 104 hypothetical protein YP_884018.1 5031559 D 243243 CDS YP_884019.1 118462487 4530683 complement(5032690..5032893) 1 NC_008595.1 hypothetical protein 5032893 4530683 MAV_4898 Mycobacterium avium 104 hypothetical protein YP_884019.1 5032690 R 243243 CDS YP_884020.1 118464907 4530742 5032879..5034270 1 NC_008595.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 5034270 4530742 MAV_4899 Mycobacterium avium 104 transporter, major facilitator family protein YP_884020.1 5032879 D 243243 CDS YP_884021.1 118464556 4530775 5034348..5035511 1 NC_008595.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 5035511 4530775 MAV_4900 Mycobacterium avium 104 bifunctional uroporphyrinogen-III synthetase/response regulator domain protein YP_884021.1 5034348 D 243243 CDS YP_884022.1 118463761 4528005 5035502..5036275 1 NC_008595.1 identified by match to protein family HMM PF01903; sirohydrochlorin cobaltochelatase, putative 5036275 4528005 MAV_4901 Mycobacterium avium 104 sirohydrochlorin cobaltochelatase, putative YP_884022.1 5035502 D 243243 CDS YP_884023.1 118463451 4529693 5036349..5036759 1 NC_008595.1 hypothetical protein 5036759 4529693 MAV_4902 Mycobacterium avium 104 hypothetical protein YP_884023.1 5036349 D 243243 CDS YP_884024.1 118462720 4530094 complement(5036764..5037132) 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM TIGR02378; nitrite reductase [NAD(P)H], small subunit 5037132 nirD 4530094 nirD Mycobacterium avium 104 nitrite reductase [NAD(P)H], small subunit YP_884024.1 5036764 R 243243 CDS YP_884025.1 118466203 4530193 complement(5037156..5039657) 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; nitrite reductase [NAD(P)H], large subunit 5039657 nirB 4530193 nirB Mycobacterium avium 104 nitrite reductase [NAD(P)H], large subunit YP_884025.1 5037156 R 243243 CDS YP_884026.1 118467216 4529597 complement(5039791..5039907) 1 NC_008595.1 hypothetical protein 5039907 4529597 MAV_4905 Mycobacterium avium 104 hypothetical protein YP_884026.1 5039791 R 243243 CDS YP_884027.1 118466755 4526356 5039951..5040391 1 NC_008595.1 identified by match to protein family HMM PF00011; Hsp20/alpha crystallin family protein 5040391 4526356 MAV_4906 Mycobacterium avium 104 Hsp20/alpha crystallin family protein YP_884027.1 5039951 D 243243 CDS YP_884028.1 118466610 4526847 5040618..5040932 1 NC_008595.1 hypothetical protein 5040932 4526847 MAV_4907 Mycobacterium avium 104 hypothetical protein YP_884028.1 5040618 D 243243 CDS YP_884029.1 118465127 4530480 5041026..5041853 1 NC_008595.1 integral membrane protein 5041853 4530480 MAV_4908 Mycobacterium avium 104 integral membrane protein YP_884029.1 5041026 D 243243 CDS YP_884030.1 118465120 4530472 5041896..5043836 1 NC_008595.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 5043836 sdhA 4530472 sdhA Mycobacterium avium 104 succinate dehydrogenase flavoprotein subunit YP_884030.1 5041896 D 243243 CDS YP_884031.1 118465893 4527927 5043833..5044579 1 NC_008595.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 5044579 4527927 MAV_4910 Mycobacterium avium 104 fumarate reductase iron-sulfur subunit YP_884031.1 5043833 D 243243 CDS YP_884032.1 118465510 4528927 5044690..5044854 1 NC_008595.1 hypothetical protein 5044854 4528927 MAV_4911 Mycobacterium avium 104 hypothetical protein YP_884032.1 5044690 D 243243 CDS YP_884033.1 118464513 4529433 complement(5044895..5045383) 1 NC_008595.1 identified by match to protein family HMM PF01613; NADH-FMN oxidoreductase 5045383 4529433 MAV_4912 Mycobacterium avium 104 NADH-FMN oxidoreductase YP_884033.1 5044895 R 243243 CDS YP_884034.1 118462782 4527279 complement(5045480..5046517) 1 NC_008595.1 identified by match to protein family HMM PF03171; oxidoreductase, 2OG-Fe(II) oxygenase 5046517 4527279 MAV_4913 Mycobacterium avium 104 oxidoreductase, 2OG-Fe(II) oxygenase YP_884034.1 5045480 R 243243 CDS YP_884035.1 118462700 4526680 5046719..5048554 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 5048554 4526680 MAV_4914 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884035.1 5046719 D 243243 CDS YP_884036.1 118463462 4529704 complement(5048876..5050159) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 5050159 4529704 MAV_4915 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_884036.1 5048876 R 243243 CDS YP_884037.1 118466089 4527357 5050375..5051739 1 NC_008595.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 5051739 fabG 4527357 fabG Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_884037.1 5050375 D 243243 CDS YP_884038.1 118466814 4527379 5051736..5052581 1 NC_008595.1 identified by match to protein family HMM PF01575; MaoC like domain-containing protein 5052581 4527379 MAV_4917 Mycobacterium avium 104 MaoC like domain-containing protein YP_884038.1 5051736 D 243243 CDS YP_884039.1 118466998 4529526 complement(5052583..5053836) 1 NC_008595.1 identified by match to protein family HMM PF00654; chloride transporter, chloride channel (ClC) family protein 5053836 4529526 MAV_4918 Mycobacterium avium 104 chloride transporter, chloride channel (ClC) family protein YP_884039.1 5052583 R 243243 CDS YP_884040.1 118463516 4527696 complement(5053862..5054509) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5054509 4527696 MAV_4919 Mycobacterium avium 104 TetR family transcriptional regulator YP_884040.1 5053862 R 243243 CDS YP_884041.1 118464303 4526633 complement(5054575..5055741) 1 NC_008595.1 identified by match to protein family HMM PF00933; glycosyl hydrolase 3 5055741 4526633 MAV_4920 Mycobacterium avium 104 glycosyl hydrolase 3 YP_884041.1 5054575 R 243243 CDS YP_884042.1 118465031 4530080 complement(5055754..5055981) 1 NC_008595.1 hypothetical protein 5055981 4530080 MAV_4921 Mycobacterium avium 104 hypothetical protein YP_884042.1 5055754 R 243243 CDS YP_884043.1 118465903 4528985 5056201..5056326 1 NC_008595.1 secreted protein 5056326 4528985 MAV_4922 Mycobacterium avium 104 secreted protein YP_884043.1 5056201 D 243243 CDS YP_884044.1 118466978 4530377 5056400..5060581 1 NC_008595.1 hypothetical protein 5060581 4530377 MAV_4923 Mycobacterium avium 104 hypothetical protein YP_884044.1 5056400 D 243243 CDS YP_884045.1 118467063 4526441 5060669..5062126 1 NC_008595.1 identified by match to protein family HMM PF06762; integral membrane protein 5062126 4526441 MAV_4924 Mycobacterium avium 104 integral membrane protein YP_884045.1 5060669 D 243243 CDS YP_884046.1 118462653 4529080 complement(5062310..5064106) 1 NC_008595.1 identified by match to protein family HMM PF00732; match to protein family HMM PF05199; glucose-methanol-choline 5064106 4529080 MAV_4925 Mycobacterium avium 104 glucose-methanol-choline YP_884046.1 5062310 R 243243 CDS YP_884047.1 118463936 4528116 complement(5064326..5065780) 1 NC_008595.1 identified by similarity to SP:P26901; match to protein family HMM PF00199; catalase KatA 5065780 katA 4528116 katA Mycobacterium avium 104 catalase KatA YP_884047.1 5064326 R 243243 CDS YP_884048.1 118464791 4526715 complement(5065806..5067263) 1 NC_008595.1 identified by similarity to SP:P26901; match to protein family HMM PF00199; catalase KatA 5067263 katA 4526715 katA Mycobacterium avium 104 catalase KatA YP_884048.1 5065806 R 243243 CDS YP_884049.1 118464856 4527972 complement(5067343..5067690) 1 NC_008595.1 hypothetical protein 5067690 4527972 MAV_4928 Mycobacterium avium 104 hypothetical protein YP_884049.1 5067343 R 243243 CDS YP_884050.1 118465253 4528471 5067679..5067819 1 NC_008595.1 hypothetical protein 5067819 4528471 MAV_4929 Mycobacterium avium 104 hypothetical protein YP_884050.1 5067679 D 243243 CDS YP_884051.1 118465829 4525501 5068202..5069344 1 NC_008595.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase 5069344 4525501 MAV_4930 Mycobacterium avium 104 formate dehydrogenase YP_884051.1 5068202 D 243243 CDS YP_884052.1 118465125 4530478 complement(5069360..5070370) 1 NC_008595.1 hypothetical protein 5070370 4530478 MAV_4931 Mycobacterium avium 104 hypothetical protein YP_884052.1 5069360 R 243243 CDS YP_884053.1 118465890 4527924 complement(5070545..5070913) 1 NC_008595.1 identified by match to protein family HMM PF00903; glyoxalase 5070913 4527924 MAV_4932 Mycobacterium avium 104 glyoxalase YP_884053.1 5070545 R 243243 CDS YP_884054.1 118463670 4525962 complement(5070954..5072168) 1 NC_008595.1 hypothetical protein 5072168 4525962 MAV_4933 Mycobacterium avium 104 hypothetical protein YP_884054.1 5070954 R 243243 CDS YP_884055.1 118464425 4530246 complement(5072415..5073344) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 5073344 4530246 MAV_4934 Mycobacterium avium 104 LysR family transcriptional regulator YP_884055.1 5072415 R 243243 CDS YP_884056.1 118462972 4527400 complement(5073384..5075030) 1 NC_008595.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis; acetolactate synthase 5075030 4527400 MAV_4935 Mycobacterium avium 104 acetolactate synthase YP_884056.1 5073384 R 243243 CDS YP_884057.1 118462265 4526409 5075111..5076529 1 NC_008595.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 5076529 gabD1 4526409 gabD1 Mycobacterium avium 104 succinic semialdehyde dehydrogenase YP_884057.1 5075111 D 243243 CDS YP_884058.1 118465897 4527931 complement(5076596..5077531) 1 NC_008595.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit beta 5077531 4527931 MAV_4937 Mycobacterium avium 104 ribonucleotide-diphosphate reductase subunit beta YP_884058.1 5076596 R 243243 CDS YP_884059.1 118463620 4527324 complement(5077528..5078211) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5078211 4527324 MAV_4938 Mycobacterium avium 104 TetR family transcriptional regulator YP_884059.1 5077528 R 243243 CDS YP_884060.1 118463316 4529556 complement(5078415..5080124) 1 NC_008595.1 identified by match to protein family HMM PF00441; acyl-CoA dehydrogenase 5080124 4529556 MAV_4939 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884060.1 5078415 R 243243 CDS YP_884061.1 118462554 4530555 5080310..5081230 1 NC_008595.1 identified by match to protein family HMM PF02126; phosphotriesterase-like protein 5081230 4530555 MAV_4940 Mycobacterium avium 104 phosphotriesterase-like protein YP_884061.1 5080310 D 243243 CDS YP_884062.1 118464790 4526714 complement(5081264..5082445) 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase 5082445 4526714 MAV_4941 Mycobacterium avium 104 acyltransferase YP_884062.1 5081264 R 243243 CDS YP_884063.1 118465561 4526746 5082612..5083868 1 NC_008595.1 hypothetical protein 5083868 4526746 MAV_4942 Mycobacterium avium 104 hypothetical protein YP_884063.1 5082612 D 243243 CDS YP_884064.1 118466442 4527115 5083877..5085574 1 NC_008595.1 hypothetical protein 5085574 4527115 MAV_4944 Mycobacterium avium 104 hypothetical protein YP_884064.1 5083877 D 243243 CDS YP_884065.1 118464919 4528559 complement(5085558..5086706) 1 NC_008595.1 identified by match to protein family HMM PF00534; glycosyltransferase 5086706 4528559 MAV_4943 Mycobacterium avium 104 glycosyltransferase YP_884065.1 5085558 R 243243 CDS YP_884066.1 118466390 4526191 5086812..5087573 1 NC_008595.1 SAM-dependent methyltransferase 5087573 4526191 MAV_4945 Mycobacterium avium 104 SAM-dependent methyltransferase YP_884066.1 5086812 D 243243 CDS YP_884067.1 118462788 4525756 5087619..5089100 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 5089100 4525756 MAV_4946 Mycobacterium avium 104 aldehyde dehydrogenase YP_884067.1 5087619 D 243243 CDS YP_884068.1 118465927 4528486 5089416..5089547 1 NC_008595.1 hypothetical protein 5089547 4528486 MAV_4947 Mycobacterium avium 104 hypothetical protein YP_884068.1 5089416 D 243243 CDS YP_884069.1 118467192 4528426 5089572..5090213 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5090213 4528426 MAV_4948 Mycobacterium avium 104 TetR family transcriptional regulator YP_884069.1 5089572 D 243243 CDS YP_884070.1 118466452 4527125 complement(5090215..5090511) 1 NC_008595.1 hypothetical protein 5090511 4527125 MAV_4949 Mycobacterium avium 104 hypothetical protein YP_884070.1 5090215 R 243243 CDS YP_884071.1 118466293 4529539 complement(5090532..5092061) 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-dependent synthetase and ligase 5092061 4529539 MAV_4950 Mycobacterium avium 104 AMP-dependent synthetase and ligase YP_884071.1 5090532 R 243243 CDS YP_884072.1 118463001 4530631 complement(5092149..5092943) 1 NC_008595.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 5092943 4530631 MAV_4951 Mycobacterium avium 104 enoyl-CoA hydratase YP_884072.1 5092149 R 243243 CDS YP_884073.1 118463422 4530059 complement(5093074..5094483) 1 NC_008595.1 identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; acyltransferase, ws/dgat/mgat subfamily protein 5094483 4530059 MAV_4952 Mycobacterium avium 104 acyltransferase, ws/dgat/mgat subfamily protein YP_884073.1 5093074 R 243243 CDS YP_884074.1 118462704 4526685 complement(5094528..5095724) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 5095724 4526685 MAV_4953 Mycobacterium avium 104 alpha/beta hydrolase YP_884074.1 5094528 R 243243 CDS YP_884075.1 118464657 4528254 5095974..5096897 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 5096897 4528254 MAV_4954 Mycobacterium avium 104 alpha/beta hydrolase YP_884075.1 5095974 D 243243 CDS YP_884076.1 118463910 4525841 complement(5096900..5098213) 1 NC_008595.1 identified by match to protein family HMM PF07969; amidohydrolase 5098213 4525841 MAV_4955 Mycobacterium avium 104 amidohydrolase YP_884076.1 5096900 R 243243 CDS YP_884077.1 118465178 4528668 complement(5098207..5099397) 1 NC_008595.1 hypothetical protein 5099397 4528668 MAV_4956 Mycobacterium avium 104 hypothetical protein YP_884077.1 5098207 R 243243 CDS YP_884078.1 118463152 4527790 complement(5099514..5100536) 1 NC_008595.1 p40 protein 5100536 4527790 MAV_4957 Mycobacterium avium 104 p40 protein YP_884078.1 5099514 R 243243 CDS YP_884079.1 118466488 4527618 5100670..5101818 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5101818 4527618 MAV_4958 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884079.1 5100670 D 243243 CDS YP_884080.1 118467205 4528440 5101896..5102384 1 NC_008595.1 hypothetical protein 5102384 4528440 MAV_4959 Mycobacterium avium 104 hypothetical protein YP_884080.1 5101896 D 243243 CDS YP_884081.1 118465352 4526665 complement(5102480..5103442) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 5103442 4526665 MAV_4960 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_884081.1 5102480 R 243243 CDS YP_884082.1 118465342 4526655 complement(5103446..5104963) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 5104963 4526655 MAV_4961 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_884082.1 5103446 R 243243 CDS YP_884083.1 118466053 4530023 5105131..5106216 1 NC_008595.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; sensor histidine kinase 5106216 4530023 MAV_4962 Mycobacterium avium 104 sensor histidine kinase YP_884083.1 5105131 D 243243 CDS YP_884084.1 118464225 4528598 complement(5106233..5108062) 1 NC_008595.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 5108062 4528598 MAV_4963 Mycobacterium avium 104 phosphoenolpyruvate carboxykinase YP_884084.1 5106233 R 243243 CDS YP_884085.1 118462448 4525621 complement(5108219..5109754) 1 NC_008595.1 hypothetical protein 5109754 4525621 MAV_4964 Mycobacterium avium 104 hypothetical protein YP_884085.1 5108219 R 243243 CDS YP_884086.1 118462452 4525625 complement(5109751..5110857) 1 NC_008595.1 hypothetical protein 5110857 4525625 MAV_4965 Mycobacterium avium 104 hypothetical protein YP_884086.1 5109751 R 243243 CDS YP_884087.1 118464509 4525552 5111051..5111830 1 NC_008595.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 5111830 trmB 4525552 trmB Mycobacterium avium 104 tRNA (guanine-N(7)-)-methyltransferase YP_884087.1 5111051 D 243243 CDS YP_884088.1 118463993 4530352 5111863..5112576 1 NC_008595.1 hypothetical protein 5112576 4530352 MAV_4967 Mycobacterium avium 104 hypothetical protein YP_884088.1 5111863 D 243243 CDS YP_884089.1 118464977 4527469 5112659..5115508 1 NC_008595.1 MmpL3 protein 5115508 4527469 MAV_4968 Mycobacterium avium 104 MmpL3 protein YP_884089.1 5112659 D 243243 CDS YP_884090.1 118466956 4530268 complement(5115524..5116672) 1 NC_008595.1 identified by match to protein family HMM PF01594; hypothetical protein 5116672 4530268 MAV_4969 Mycobacterium avium 104 hypothetical protein YP_884090.1 5115524 R 243243 CDS YP_884091.1 118466128 4529761 5116841..5118022 1 NC_008595.1 identified by match to protein family HMM PF03706; match to protein family HMM TIGR00374; hypothetical protein 5118022 4529761 MAV_4970 Mycobacterium avium 104 hypothetical protein YP_884091.1 5116841 D 243243 CDS YP_884092.1 118462996 4530626 complement(5118108..5118653) 1 NC_008595.1 hypothetical protein 5118653 4530626 MAV_4971 Mycobacterium avium 104 hypothetical protein YP_884092.1 5118108 R 243243 CDS YP_884093.1 118463807 4526062 complement(5118664..5118789) 1 NC_008595.1 hypothetical protein 5118789 4526062 MAV_4972 Mycobacterium avium 104 hypothetical protein YP_884093.1 5118664 R 243243 CDS YP_884094.1 118462726 4530100 5119003..5122026 1 NC_008595.1 MmpL11 protein 5122026 4530100 MAV_4973 Mycobacterium avium 104 MmpL11 protein YP_884094.1 5119003 D 243243 CDS YP_884095.1 118464758 4527654 5122023..5122562 1 NC_008595.1 hypothetical protein 5122562 4527654 MAV_4974 Mycobacterium avium 104 hypothetical protein YP_884095.1 5122023 D 243243 CDS YP_884096.1 118464479 4528853 complement(5122578..5123261) 1 NC_008595.1 transmembrane protein 5123261 4528853 MAV_4975 Mycobacterium avium 104 transmembrane protein YP_884096.1 5122578 R 243243 CDS YP_884097.1 118465161 4529251 complement(5123270..5123899) 1 NC_008595.1 hypothetical protein 5123899 4529251 MAV_4976 Mycobacterium avium 104 hypothetical protein YP_884097.1 5123270 R 243243 CDS YP_884098.1 118465544 4525792 5123941..5125929 1 NC_008595.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; peptidase M13 5125929 4525792 MAV_4977 Mycobacterium avium 104 peptidase M13 YP_884098.1 5123941 D 243243 CDS YP_884099.1 118464832 4529737 complement(5125963..5126478) 1 NC_008595.1 identified by match to protein family HMM PF00210; starvation-inducible DNA-binding protein or fine tangled pili major subunit 5126478 4529737 MAV_4978 Mycobacterium avium 104 starvation-inducible DNA-binding protein or fine tangled pili major subunit YP_884099.1 5125963 R 243243 CDS YP_884100.1 118467016 4529486 complement(5126626..5127549) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 5127549 4529486 MAV_4979 Mycobacterium avium 104 LysR family transcriptional regulator YP_884100.1 5126626 R 243243 CDS YP_884101.1 118466309 4528351 complement(5127683..5128990) 1 NC_008595.1 identified by match to protein family HMM PF00732; match to protein family HMM PF05199; choline dehydrogenase 5128990 4528351 MAV_4980 Mycobacterium avium 104 choline dehydrogenase YP_884101.1 5127683 R 243243 CDS YP_884102.1 118462571 4528630 complement(5129487..5130461) 1 NC_008595.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 5130461 4528630 MAV_4981 Mycobacterium avium 104 AraC family transcriptional regulator YP_884102.1 5129487 R 243243 CDS YP_884103.1 118464445 4525976 5130584..5131450 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase/reductase SDR 5131450 4525976 MAV_4982 Mycobacterium avium 104 short chain dehydrogenase/reductase SDR YP_884103.1 5130584 D 243243 CDS YP_884104.1 118465921 4528480 5131489..5132301 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase-1 5132301 4528480 MAV_4984 Mycobacterium avium 104 alpha/beta hydrolase-1 YP_884104.1 5131489 D 243243 CDS YP_884105.1 118464133 4528835 complement(5132291..5134528) 1 NC_008595.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; molybdopterin oxidoreductase Fe4S4 subunit 5134528 4528835 MAV_4983 Mycobacterium avium 104 molybdopterin oxidoreductase Fe4S4 subunit YP_884105.1 5132291 R 243243 CDS YP_884106.1 118463812 4526067 complement(5134518..5135123) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5135123 4526067 MAV_4985 Mycobacterium avium 104 TetR family transcriptional regulator YP_884106.1 5134518 R 243243 CDS YP_884107.1 118462430 4528293 complement(5135233..5136252) 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 5136252 4528293 MAV_4986 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_884107.1 5135233 R 243243 CDS YP_884108.1 118467145 4527159 complement(5136371..5137606) 1 NC_008595.1 identified by match to protein family HMM PF07690; sugar transporter family protein 5137606 4527159 MAV_4987 Mycobacterium avium 104 sugar transporter family protein YP_884108.1 5136371 R 243243 CDS YP_884109.1 118466419 4530163 complement(5137729..5138019) 1 NC_008595.1 identified by match to protein family HMM PF02583; hypothetical protein 5138019 4530163 MAV_4988 Mycobacterium avium 104 hypothetical protein YP_884109.1 5137729 R 243243 CDS YP_884110.1 118466019 4529905 5138142..5139869 1 NC_008595.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 5139869 ilvD 4529905 ilvD Mycobacterium avium 104 dihydroxy-acid dehydratase YP_884110.1 5138142 D 243243 CDS YP_884111.1 118464524 4529444 5140677..5141660 1 NC_008595.1 identified by similarity to GB:AAF98273.1; match to protein family HMM PF03060; oxidoreductase, 2-nitropropane dioxygenase 5141660 4529444 MAV_4991 Mycobacterium avium 104 oxidoreductase, 2-nitropropane dioxygenase YP_884111.1 5140677 D 243243 CDS YP_884112.1 118462783 4527280 complement(5141664..5142317) 1 NC_008595.1 identified by match to protein family HMM PF01596; O-methyltransferase 5142317 4527280 MAV_4992 Mycobacterium avium 104 O-methyltransferase YP_884112.1 5141664 R 243243 CDS YP_884113.1 118462867 4527094 5142450..5142605 1 NC_008595.1 hypothetical protein 5142605 4527094 MAV_4993 Mycobacterium avium 104 hypothetical protein YP_884113.1 5142450 D 243243 CDS YP_884114.1 118463402 4528029 complement(5142636..5144753) 1 NC_008595.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915; glycosyl hydrolase 3 5144753 4528029 MAV_4994 Mycobacterium avium 104 glycosyl hydrolase 3 YP_884114.1 5142636 R 243243 CDS YP_884115.1 118466178 4526209 complement(5144750..5145262) 1 NC_008595.1 hypothetical protein 5145262 4526209 MAV_4995 Mycobacterium avium 104 hypothetical protein YP_884115.1 5144750 R 243243 CDS YP_884116.1 118466913 4529458 complement(5145259..5146008) 1 NC_008595.1 hypothetical protein 5146008 4529458 MAV_4996 Mycobacterium avium 104 hypothetical protein YP_884116.1 5145259 R 243243 CDS YP_884117.1 118466327 4528758 complement(5146187..5147020) 1 NC_008595.1 identified by match to protein family HMM PF00561; lysophospholipase 5147020 4528758 MAV_4997 Mycobacterium avium 104 lysophospholipase YP_884117.1 5146187 R 243243 CDS YP_884118.1 118464903 4530738 5147137..5148120 1 NC_008595.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 5148120 4530738 MAV_4998 Mycobacterium avium 104 RNA polymerase factor sigma-70 YP_884118.1 5147137 D 243243 CDS YP_884119.1 118464697 4527886 5148117..5149520 1 NC_008595.1 hypothetical protein 5149520 4527886 MAV_5000 Mycobacterium avium 104 hypothetical protein YP_884119.1 5148117 D 243243 CDS YP_884120.1 118466966 4530365 complement(5149517..5150650) 1 NC_008595.1 identified by match to protein family HMM PF01113; dihydrodipicolinate reductase N-terminus domain-containing protein 5150650 dapB 4530365 dapB Mycobacterium avium 104 dihydrodipicolinate reductase N-terminus domain-containing protein YP_884120.1 5149517 R 243243 CDS YP_884121.1 118466267 4527819 5150713..5151603 1 NC_008595.1 hypothetical protein 5151603 4527819 MAV_5001 Mycobacterium avium 104 hypothetical protein YP_884121.1 5150713 D 243243 CDS YP_884122.1 118465541 4530017 5151629..5152354 1 NC_008595.1 identified by match to protein family HMM PF02678; YhhW protein 5152354 4530017 MAV_5002 Mycobacterium avium 104 YhhW protein YP_884122.1 5151629 D 243243 CDS YP_884123.1 118465577 4526763 5152413..5153837 1 NC_008595.1 identified by match to protein family HMM PF01061; ABC transporter 5153837 4526763 MAV_5003 Mycobacterium avium 104 ABC transporter YP_884123.1 5152413 D 243243 CDS YP_884124.1 118466643 4528081 5153944..5155026 1 NC_008595.1 LprO protein 5155026 4528081 MAV_5005 Mycobacterium avium 104 LprO protein YP_884124.1 5153944 D 243243 CDS YP_884125.1 118462784 4525752 complement(5155019..5155684) 1 NC_008595.1 identified by match to protein family HMM PF06912; hypothetical protein 5155684 4525752 MAV_5004 Mycobacterium avium 104 hypothetical protein YP_884125.1 5155019 R 243243 CDS YP_884126.1 118465948 4527944 complement(5155749..5156504) 1 NC_008595.1 hypothetical protein 5156504 4527944 MAV_5006 Mycobacterium avium 104 hypothetical protein YP_884126.1 5155749 R 243243 CDS YP_884127.1 118464257 4527442 complement(5156471..5157025) 1 NC_008595.1 hypothetical protein 5157025 4527442 MAV_5007 Mycobacterium avium 104 hypothetical protein YP_884127.1 5156471 R 243243 CDS YP_884128.1 118463532 4526838 complement(5157022..5157993) 1 NC_008595.1 identified by match to protein family HMM PF06271; RDD family protein 5157993 4526838 MAV_5008 Mycobacterium avium 104 RDD family protein YP_884128.1 5157022 R 243243 CDS YP_884129.1 118462976 4527404 complement(5157990..5158691) 1 NC_008595.1 hypothetical protein 5158691 4527404 MAV_5009 Mycobacterium avium 104 hypothetical protein YP_884129.1 5157990 R 243243 CDS YP_884130.1 118462429 4528292 complement(5158661..5159602) 1 NC_008595.1 mce-family protein mce1f 5159602 4528292 MAV_5010 Mycobacterium avium 104 mce-family protein mce1f YP_884130.1 5158661 R 243243 CDS YP_884131.1 118466982 4530381 complement(5159574..5161364) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 5161364 4530381 MAV_5011 Mycobacterium avium 104 virulence factor Mce YP_884131.1 5159574 R 243243 CDS YP_884132.1 118466487 4527617 complement(5161436..5163049) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; mce-family protein mce1d 5163049 4527617 MAV_5012 Mycobacterium avium 104 mce-family protein mce1d YP_884132.1 5161436 R 243243 CDS YP_884133.1 118467050 4526506 complement(5163046..5164611) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; mce-family protein mce1c 5164611 4526506 MAV_5013 Mycobacterium avium 104 mce-family protein mce1c YP_884133.1 5163046 R 243243 CDS YP_884134.1 118463171 4529873 complement(5164608..5165648) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 5165648 4529873 MAV_5014 Mycobacterium avium 104 virulence factor Mce YP_884134.1 5164608 R 243243 CDS YP_884135.1 118465982 4526124 complement(5165645..5166949) 1 NC_008595.1 identified by match to protein family HMM PF02470; match to protein family HMM TIGR00996; virulence factor Mce 5166949 4526124 MAV_5015 Mycobacterium avium 104 virulence factor Mce YP_884135.1 5165645 R 243243 CDS YP_884136.1 118463838 4526057 complement(5166955..5167824) 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 5167824 4526057 MAV_5016 Mycobacterium avium 104 hypothetical protein YP_884136.1 5166955 R 243243 CDS YP_884137.1 118464753 4527649 complement(5167826..5168602) 1 NC_008595.1 identified by match to protein family HMM PF02405; hypothetical protein 5168602 4527649 MAV_5017 Mycobacterium avium 104 hypothetical protein YP_884137.1 5167826 R 243243 CDS YP_884138.1 118462717 4530091 complement(5168941..5170536) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 5170536 4530091 MAV_5018 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_884138.1 5168941 R 243243 CDS YP_884139.1 118466214 4528893 5170711..5171400 1 NC_008595.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 5171400 4528893 MAV_5020 Mycobacterium avium 104 GntR family transcriptional regulator YP_884139.1 5170711 D 243243 CDS YP_884140.1 118466430 4530174 complement(5171397..5171837) 1 NC_008595.1 similar to streptomyces cyclase/dehydrase; identified by match to protein family HMM PF03364; cyclase/dehydrase 5171837 4530174 MAV_5019 Mycobacterium avium 104 cyclase/dehydrase YP_884140.1 5171397 R 243243 CDS YP_884141.1 118464807 4527626 complement(5171881..5172327) 1 NC_008595.1 identified by match to protein family HMM PF03061; thioesterase 5172327 4527626 MAV_5021 Mycobacterium avium 104 thioesterase YP_884141.1 5171881 R 243243 CDS YP_884142.1 118465666 4526738 5172402..5173493 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 5173493 4526738 MAV_5022 Mycobacterium avium 104 zinc-binding dehydrogenase YP_884142.1 5172402 D 243243 CDS YP_884143.1 118464946 4528207 5173587..5173835 1 NC_008595.1 hypothetical protein 5173835 4528207 MAV_5023 Mycobacterium avium 104 hypothetical protein YP_884143.1 5173587 D 243243 CDS YP_884144.1 118463639 4528541 5174437..5176800 1 NC_008595.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; type I restriction-modification system, R subunit 5176800 4528541 MAV_5024 Mycobacterium avium 104 type I restriction-modification system, R subunit YP_884144.1 5174437 D 243243 CDS YP_884145.1 118464483 4528857 5176872..5177468 1 NC_008595.1 hypothetical protein 5177468 4528857 MAV_5025 Mycobacterium avium 104 hypothetical protein YP_884145.1 5176872 D 243243 CDS YP_884146.1 118462531 4527674 5177519..5178331 1 NC_008595.1 hypothetical protein 5178331 4527674 MAV_5026 Mycobacterium avium 104 hypothetical protein YP_884146.1 5177519 D 243243 CDS YP_884147.1 118466595 4529361 5178332..5179819 1 NC_008595.1 identified by match to protein family HMM PF02384; type I restriction-modification system, M subunit 5179819 4529361 MAV_5027 Mycobacterium avium 104 type I restriction-modification system, M subunit YP_884147.1 5178332 D 243243 CDS YP_884148.1 118464916 4530751 complement(5180992..5181192) 1 NC_008595.1 DNA repair protein RadC 5181192 4530751 MAV_5028 Mycobacterium avium 104 DNA repair protein RadC YP_884148.1 5180992 R 243243 CDS YP_884149.1 118467300 4527259 5181281..5182555 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 5182555 4527259 MAV_5030 Mycobacterium avium 104 transposase, Mutator family protein YP_884149.1 5181281 D 243243 CDS YP_884150.1 118462338 4525683 complement(5182559..5182756) 1 NC_008595.1 hypothetical protein 5182756 4525683 MAV_5031 Mycobacterium avium 104 hypothetical protein YP_884150.1 5182559 R 243243 CDS YP_884151.1 118463721 4528071 complement(5182819..5183520) 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR-family protein transcriptional regulator 5183520 4528071 MAV_5032 Mycobacterium avium 104 GntR-family protein transcriptional regulator YP_884151.1 5182819 R 243243 CDS YP_884152.1 118465519 4528936 complement(5183744..5184622) 1 NC_008595.1 identified by match to protein family HMM PF03781; sulfatase-modifying factor 1 5184622 4528936 MAV_5033 Mycobacterium avium 104 sulfatase-modifying factor 1 YP_884152.1 5183744 R 243243 CDS YP_884153.1 118464552 4530771 complement(5184637..5185281) 1 NC_008595.1 identified by match to protein family HMM PF02371; transposase 5185281 4530771 MAV_5034 Mycobacterium avium 104 transposase YP_884153.1 5184637 R 243243 CDS YP_884154.1 118465469 4526237 5185455..5185799 1 NC_008595.1 identified by match to protein family HMM PF01527; ISAfe7, transposase OrfA 5185799 4526237 MAV_5035 Mycobacterium avium 104 ISAfe7, transposase OrfA YP_884154.1 5185455 D 243243 CDS YP_884155.1 118462709 4530082 5185877..5186716 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 5186716 4530082 MAV_5037 Mycobacterium avium 104 transposase YP_884155.1 5185877 D 243243 CDS YP_884156.1 118463326 4529566 complement(5186671..5187039) 1 NC_008595.1 transposase 5187039 4529566 MAV_5036 Mycobacterium avium 104 transposase YP_884156.1 5186671 R 243243 CDS YP_884157.1 118466678 4526628 complement(5187274..5187402) 1 NC_008595.1 hypothetical protein 5187402 4526628 MAV_5038 Mycobacterium avium 104 hypothetical protein YP_884157.1 5187274 R 243243 CDS YP_884158.1 118466335 4528766 complement(5187670..5188944) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 5188944 4528766 MAV_5039 Mycobacterium avium 104 transposase, Mutator family protein YP_884158.1 5187670 R 243243 CDS YP_884159.1 118463244 4525780 complement(5188993..5190039) 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 5190039 4525780 MAV_5040 Mycobacterium avium 104 transposase, Mutator family protein YP_884159.1 5188993 R 243243 CDS YP_884160.1 118464922 4528562 5190268..5190579 1 NC_008595.1 hypothetical protein 5190579 4528562 MAV_5041 Mycobacterium avium 104 hypothetical protein YP_884160.1 5190268 D 243243 CDS YP_884161.1 118463343 4529213 complement(5190665..5191315) 1 NC_008595.1 hypothetical protein 5191315 4529213 MAV_5042 Mycobacterium avium 104 hypothetical protein YP_884161.1 5190665 R 243243 CDS YP_884162.1 118464567 4530786 complement(5191312..5191725) 1 NC_008595.1 hypothetical protein 5191725 4530786 MAV_5043 Mycobacterium avium 104 hypothetical protein YP_884162.1 5191312 R 243243 CDS YP_884163.1 118465080 4525897 complement(5191806..5192228) 1 NC_008595.1 hypothetical protein 5192228 4525897 MAV_5044 Mycobacterium avium 104 hypothetical protein YP_884163.1 5191806 R 243243 CDS YP_884164.1 118466883 4526702 complement(5192381..5193013) 1 NC_008595.1 hypothetical protein 5193013 4526702 MAV_5045 Mycobacterium avium 104 hypothetical protein YP_884164.1 5192381 R 243243 CDS YP_884165.1 118465472 4527225 complement(5193070..5193756) 1 NC_008595.1 hypothetical protein 5193756 4527225 MAV_5046 Mycobacterium avium 104 hypothetical protein YP_884165.1 5193070 R 243243 CDS YP_884166.1 118464887 4529616 complement(5193791..5194750) 1 NC_008595.1 identified by match to protein family HMM PF02470; Mce family protein 5194750 4529616 MAV_5047 Mycobacterium avium 104 Mce family protein YP_884166.1 5193791 R 243243 CDS YP_884167.1 118462673 4530600 complement(5194747..5195673) 1 NC_008595.1 identified by match to protein family HMM PF02470; Mce family protein 5195673 4530600 MAV_5048 Mycobacterium avium 104 Mce family protein YP_884167.1 5194747 R 243243 CDS YP_884168.1 118462269 4526414 complement(5195745..5196863) 1 NC_008595.1 identified by match to protein family HMM PF02470; Mce family protein 5196863 4526414 MAV_5049 Mycobacterium avium 104 Mce family protein YP_884168.1 5195745 R 243243 CDS YP_884169.1 118462958 4526326 complement(5196863..5197834) 1 NC_008595.1 identified by match to protein family HMM PF02470; Mce family protein 5197834 4526326 MAV_5050 Mycobacterium avium 104 Mce family protein YP_884169.1 5196863 R 243243 CDS YP_884170.1 118463697 4530584 complement(5197822..5198829) 1 NC_008595.1 identified by match to protein family HMM PF02470; Mce family protein 5198829 4530584 MAV_5051 Mycobacterium avium 104 Mce family protein YP_884170.1 5197822 R 243243 CDS YP_884171.1 118464446 4525977 complement(5198826..5199770) 1 NC_008595.1 hypothetical protein 5199770 4525977 MAV_5052 Mycobacterium avium 104 hypothetical protein YP_884171.1 5198826 R 243243 CDS YP_884172.1 118467026 4526538 complement(5200797..5201504) 1 NC_008595.1 identified by match to protein family HMM PF02405; ABC transporter transmembrane protein 5201504 4526538 MAV_5054 Mycobacterium avium 104 ABC transporter transmembrane protein YP_884172.1 5200797 R 243243 CDS YP_884173.1 118462607 4528511 complement(5202660..5203292) 1 NC_008595.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02909; TetR family transcriptional regulator 5203292 4528511 MAV_5055 Mycobacterium avium 104 TetR family transcriptional regulator YP_884173.1 5202660 R 243243 CDS YP_884174.1 118463320 4529560 5203177..5205054 1 NC_008595.1 identified by match to protein family HMM PF00391; PEP-utilizing protein 5205054 4529560 MAV_5056 Mycobacterium avium 104 PEP-utilizing protein YP_884174.1 5203177 D 243243 CDS YP_884175.1 118464031 4529003 5205054..5205971 1 NC_008595.1 hypothetical protein 5205971 4529003 MAV_5057 Mycobacterium avium 104 hypothetical protein YP_884175.1 5205054 D 243243 CDS YP_884176.1 118463559 4530714 5206133..5206630 1 NC_008595.1 hypothetical protein 5206630 4530714 MAV_5058 Mycobacterium avium 104 hypothetical protein YP_884176.1 5206133 D 243243 CDS YP_884177.1 118463958 4527204 5206627..5208141 1 NC_008595.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 5208141 4527204 MAV_5059 Mycobacterium avium 104 pyruvate phosphate dikinase YP_884177.1 5206627 D 243243 CDS YP_884178.1 118465078 4525895 5208209..5209363 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase 5209363 4525895 MAV_5060 Mycobacterium avium 104 phosphotransferase YP_884178.1 5208209 D 243243 CDS YP_884179.1 118465601 4527860 5209717..5210778 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 5210778 4527860 MAV_5061 Mycobacterium avium 104 hypothetical protein YP_884179.1 5209717 D 243243 CDS YP_884180.1 118466172 4526203 5211213..5212382 1 NC_008595.1 identified by match to protein family HMM PF00391; pyruvate, water dikinase 5212382 4526203 MAV_5062 Mycobacterium avium 104 pyruvate, water dikinase YP_884180.1 5211213 D 243243 CDS YP_884181.1 118466709 4529716 complement(5212506..5213579) 1 NC_008595.1 hypothetical protein 5213579 4529716 MAV_5063 Mycobacterium avium 104 hypothetical protein YP_884181.1 5212506 R 243243 CDS YP_884182.1 118462781 4527278 complement(5213785..5214363) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5214363 4527278 MAV_5064 Mycobacterium avium 104 TetR family transcriptional regulator YP_884182.1 5213785 R 243243 CDS YP_884183.1 118463337 4529207 5214617..5215660 1 NC_008595.1 hypothetical protein 5215660 4529207 MAV_5065 Mycobacterium avium 104 hypothetical protein YP_884183.1 5214617 D 243243 CDS YP_884184.1 118463918 4525849 complement(5215967..5216512) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5216512 4525849 MAV_5066 Mycobacterium avium 104 TetR family transcriptional regulator YP_884184.1 5215967 R 243243 CDS YP_884185.1 118465801 4526114 5216730..5216867 1 NC_008595.1 hypothetical protein 5216867 4526114 MAV_5067 Mycobacterium avium 104 hypothetical protein YP_884185.1 5216730 D 243243 CDS YP_884186.1 118463344 4529214 5216899..5218062 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5218062 4529214 MAV_5068 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884186.1 5216899 D 243243 CDS YP_884187.1 118463567 4530722 5218130..5219281 1 NC_008595.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 5219281 4530722 MAV_5069 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_884187.1 5218130 D 243243 CDS YP_884188.1 118462334 4525679 5219285..5220436 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5220436 4525679 MAV_5070 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884188.1 5219285 D 243243 CDS YP_884189.1 118466881 4526700 complement(5220495..5221679) 1 NC_008595.1 acetyl-CoA hydrolase/transferase 5221679 4526700 MAV_5071 Mycobacterium avium 104 acetyl-CoA hydrolase/transferase YP_884189.1 5220495 R 243243 CDS YP_884190.1 118467237 4529794 complement(5221672..5223207) 1 NC_008595.1 identified by match to protein family HMM PF00037; match to protein family HMM PF07992; NADPH-ferredoxin reductase fpra 5223207 4529794 MAV_5072 Mycobacterium avium 104 NADPH-ferredoxin reductase fpra YP_884190.1 5221672 R 243243 CDS YP_884191.1 118466888 4526707 5223185..5223313 1 NC_008595.1 hypothetical protein 5223313 4526707 MAV_5073 Mycobacterium avium 104 hypothetical protein YP_884191.1 5223185 D 243243 CDS YP_884192.1 118466853 4529805 complement(5223385..5224206) 1 NC_008595.1 identified by match to protein family HMM PF03328; citrate lyase 5224206 4529805 MAV_5074 Mycobacterium avium 104 citrate lyase YP_884192.1 5223385 R 243243 CDS YP_884193.1 118466693 4530435 complement(5224319..5225131) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase 5225131 4530435 MAV_5075 Mycobacterium avium 104 phosphotransferase YP_884193.1 5224319 R 243243 CDS YP_884194.1 118465153 4529243 complement(5225547..5227286) 1 NC_008595.1 identified by match to protein family HMM PF00501; acyl-CoA ligase 5227286 4529243 MAV_5076 Mycobacterium avium 104 acyl-CoA ligase YP_884194.1 5225547 R 243243 CDS YP_884195.1 118464615 4526772 complement(5227283..5228896) 1 NC_008595.1 identified by match to protein family HMM PF00501; long chain fatty acid-CoA ligase 5228896 4526772 MAV_5077 Mycobacterium avium 104 long chain fatty acid-CoA ligase YP_884195.1 5227283 R 243243 CDS YP_884196.1 118463691 4530578 complement(5228937..5229797) 1 NC_008595.1 identified by match to protein family HMM PF00106; peroxisomal hydratase-dehydrogenase-epimerase 5229797 4530578 MAV_5078 Mycobacterium avium 104 peroxisomal hydratase-dehydrogenase-epimerase YP_884196.1 5228937 R 243243 CDS YP_884197.1 118463226 4528800 complement(5229908..5231110) 1 NC_008595.1 identified by match to protein family HMM PF00108; acetyl-CoA acetyltransferase 5231110 4528800 MAV_5079 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_884197.1 5229908 R 243243 CDS YP_884198.1 118467034 4526547 complement(5231100..5232455) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 5232455 4526547 MAV_5080 Mycobacterium avium 104 hypothetical protein YP_884198.1 5231100 R 243243 CDS YP_884199.1 118465045 4525824 complement(5232452..5233660) 1 NC_008595.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 5233660 4525824 MAV_5081 Mycobacterium avium 104 acetyl-CoA acetyltransferase YP_884199.1 5232452 R 243243 CDS YP_884200.1 118463195 4527718 complement(5233657..5233914) 1 NC_008595.1 hypothetical protein 5233914 4527718 MAV_5082 Mycobacterium avium 104 hypothetical protein YP_884200.1 5233657 R 243243 CDS YP_884201.1 118462651 4529392 complement(5233926..5234462) 1 NC_008595.1 identified by match to protein family HMM PF00866; beta subunit of hydroxylase component of benzoate 1,2-dioxygenase 5234462 4529392 MAV_5083 Mycobacterium avium 104 beta subunit of hydroxylase component of benzoate 1,2-dioxygenase YP_884201.1 5233926 R 243243 CDS YP_884202.1 118462394 4525938 complement(5234467..5235735) 1 NC_008595.1 identified by match to protein family HMM PF00355; match to protein family HMM PF00848; dioxygenase large subunit 5235735 4525938 MAV_5084 Mycobacterium avium 104 dioxygenase large subunit YP_884202.1 5234467 R 243243 CDS YP_884203.1 118466750 4526351 complement(5235732..5236520) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 5236520 4526351 MAV_5085 Mycobacterium avium 104 enoyl-CoA hydratase YP_884203.1 5235732 R 243243 CDS YP_884204.1 118463524 4526829 complement(5236517..5237320) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 5237320 4526829 MAV_5086 Mycobacterium avium 104 enoyl-CoA hydratase YP_884204.1 5236517 R 243243 CDS YP_884205.1 118463105 4527167 complement(5237317..5238087) 1 NC_008595.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase/isomerase 5238087 4527167 MAV_5087 Mycobacterium avium 104 enoyl-CoA hydratase/isomerase YP_884205.1 5237317 R 243243 CDS YP_884206.1 118462444 4525617 complement(5238084..5238833) 1 NC_008595.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 5238833 fabG 4525617 fabG Mycobacterium avium 104 3-ketoacyl-(acyl-carrier-protein) reductase YP_884206.1 5238084 R 243243 CDS YP_884207.1 118466907 4528421 5238948..5239745 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF07993; oxidoreductase, short chain dehydrogenase/reductase 5239745 4528421 MAV_5089 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_884207.1 5238948 D 243243 CDS YP_884208.1 118465913 4528995 5239881..5241590 1 NC_008595.1 identified by match to protein family HMM PF01266; dehydrogenase 5241590 4528995 MAV_5090 Mycobacterium avium 104 dehydrogenase YP_884208.1 5239881 D 243243 CDS YP_884209.1 118465389 4529681 5241967..5242413 1 NC_008595.1 TetR family protein transcriptional regulator, putative 5242413 4529681 MAV_5091 Mycobacterium avium 104 TetR family protein transcriptional regulator, putative YP_884209.1 5241967 D 243243 CDS YP_884210.1 118465011 4526277 5242710..5242985 1 NC_008595.1 transposase 5242985 4526277 MAV_5092 Mycobacterium avium 104 transposase YP_884210.1 5242710 D 243243 CDS YP_884211.1 118464280 4528235 5242985..5243902 1 NC_008595.1 identified by match to protein family HMM PF00665; transposase 5243902 4528235 MAV_5093 Mycobacterium avium 104 transposase YP_884211.1 5242985 D 243243 CDS YP_884212.1 118464507 4525550 complement(5244388..5244513) 1 NC_008595.1 hypothetical protein 5244513 4525550 MAV_5094 Mycobacterium avium 104 hypothetical protein YP_884212.1 5244388 R 243243 CDS YP_884213.1 118463155 4527793 complement(5244579..5245964) 1 NC_008595.1 identified by match to protein family HMM PF00171; fatty aldehyde dehydrogenase 5245964 4527793 MAV_5095 Mycobacterium avium 104 fatty aldehyde dehydrogenase YP_884213.1 5244579 R 243243 CDS YP_884214.1 118464032 4529004 complement(5245983..5246774) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; 3-alpha-hydroxysteroid dehydrogenase 5246774 4529004 MAV_5096 Mycobacterium avium 104 3-alpha-hydroxysteroid dehydrogenase YP_884214.1 5245983 R 243243 CDS YP_884215.1 118463453 4529695 complement(5246782..5248047) 1 NC_008595.1 NikQ protein 5248047 4529695 MAV_5097 Mycobacterium avium 104 NikQ protein YP_884215.1 5246782 R 243243 CDS YP_884216.1 118462519 4527662 complement(5248044..5249507) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 5249507 4527662 MAV_5098 Mycobacterium avium 104 long-chain-fatty-acid--CoA ligase YP_884216.1 5248044 R 243243 CDS YP_884217.1 118466760 4530755 complement(5249586..5249990) 1 NC_008595.1 hypothetical protein 5249990 4530755 MAV_5099 Mycobacterium avium 104 hypothetical protein YP_884217.1 5249586 R 243243 CDS YP_884218.1 118466512 4527185 complement(5250166..5251242) 1 NC_008595.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 5251242 4527185 MAV_5100 Mycobacterium avium 104 ABC transporter ATP-binding protein YP_884218.1 5250166 R 243243 CDS YP_884219.1 118465798 4526111 5251486..5252076 1 NC_008595.1 transcriptional regulator 5252076 4526111 MAV_5101 Mycobacterium avium 104 transcriptional regulator YP_884219.1 5251486 D 243243 CDS YP_884220.1 118466418 4530162 5252138..5253142 1 NC_008595.1 p40 protein 5253142 4530162 MAV_5102 Mycobacterium avium 104 p40 protein YP_884220.1 5252138 D 243243 CDS YP_884221.1 118465312 4526566 5253384..5254658 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 5254658 4526566 MAV_5104 Mycobacterium avium 104 transposase, Mutator family protein YP_884221.1 5253384 D 243243 CDS YP_884222.1 118466294 4529540 complement(5254648..5254995) 1 NC_008595.1 identified by match to protein family HMM PF00027; Crp/Fnr family transcriptional regulator protein 5254995 4529540 MAV_5103 Mycobacterium avium 104 Crp/Fnr family transcriptional regulator protein YP_884222.1 5254648 R 243243 CDS YP_884223.1 118465799 4526112 complement(5255333..5257597) 1 NC_008595.1 identified by match to protein family HMM PF03971; match to protein family HMM TIGR00178; isocitrate dehydrogenase, NADP-dependent 5257597 4526112 MAV_5105 Mycobacterium avium 104 isocitrate dehydrogenase, NADP-dependent YP_884223.1 5255333 R 243243 CDS YP_884224.1 118463527 4526832 complement(5257692..5259551) 1 NC_008595.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 5259551 4526832 MAV_5106 Mycobacterium avium 104 phosphoenolpyruvate carboxykinase YP_884224.1 5257692 R 243243 CDS YP_884225.1 118464191 4529302 complement(5259548..5260174) 1 NC_008595.1 hypothetical protein 5260174 4529302 MAV_5107 Mycobacterium avium 104 hypothetical protein YP_884225.1 5259548 R 243243 CDS YP_884226.1 118462471 4528725 complement(5260602..5260958) 1 NC_008595.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 5260958 4528725 MAV_5108 Mycobacterium avium 104 ArsR family transcriptional regulator YP_884226.1 5260602 R 243243 CDS YP_884227.1 118463072 4527571 complement(5261050..5262528) 1 NC_008595.1 identified by match to protein family HMM PF00329; hydrogenase-4, G subunit, putative 5262528 4527571 MAV_5109 Mycobacterium avium 104 hydrogenase-4, G subunit, putative YP_884227.1 5261050 R 243243 CDS YP_884228.1 118462524 4527667 complement(5262525..5263994) 1 NC_008595.1 identified by match to protein family HMM PF00361; hydrogenase-4, F subunit, putative 5263994 4527667 MAV_5110 Mycobacterium avium 104 hydrogenase-4, F subunit, putative YP_884228.1 5262525 R 243243 CDS YP_884229.1 118463074 4527573 complement(5263994..5264656) 1 NC_008595.1 hydrogenase 4 membrane component 5264656 4527573 MAV_5111 Mycobacterium avium 104 hydrogenase 4 membrane component YP_884229.1 5263994 R 243243 CDS YP_884230.1 118465610 4527869 complement(5264669..5265628) 1 NC_008595.1 identified by match to protein family HMM PF00146; hydrogenase-4, C subunit, putative 5265628 4527869 MAV_5112 Mycobacterium avium 104 hydrogenase-4, C subunit, putative YP_884230.1 5264669 R 243243 CDS YP_884231.1 118464570 4530789 complement(5265625..5267487) 1 NC_008595.1 identified by match to protein family HMM PF00361; NADH dehydrogenase subunit n 5267487 4530789 MAV_5113 Mycobacterium avium 104 NADH dehydrogenase subunit n YP_884231.1 5265625 R 243243 CDS YP_884232.1 118463973 4527220 complement(5267598..5268005) 1 NC_008595.1 identified by match to protein family HMM PF01058; hydrogenase-4, I subunit, putative 5268005 4527220 MAV_5114 Mycobacterium avium 104 hydrogenase-4, I subunit, putative YP_884232.1 5267598 R 243243 CDS YP_884233.1 118464695 4527884 5268913..5270187 1 NC_008595.1 identified by match to protein family HMM PF00872; transposase, Mutator family protein 5270187 4527884 MAV_5116 Mycobacterium avium 104 transposase, Mutator family protein YP_884233.1 5268913 D 243243 CDS YP_884234.1 118462960 4526328 complement(5270191..5270742) 1 NC_008595.1 DNA repair protein RadC 5270742 4526328 MAV_5117 Mycobacterium avium 104 DNA repair protein RadC YP_884234.1 5270191 R 243243 CDS YP_884235.1 118466979 4530378 complement(5270784..5271710) 1 NC_008595.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 5271710 4530378 MAV_5118 Mycobacterium avium 104 alpha/beta hydrolase YP_884235.1 5270784 R 243243 CDS YP_884236.1 118466274 4527826 complement(5271707..5273221) 1 NC_008595.1 identified by match to protein family HMM PF01266; lipolytic enzyme 5273221 4527826 MAV_5119 Mycobacterium avium 104 lipolytic enzyme YP_884236.1 5271707 R 243243 CDS YP_884237.1 118467330 4526968 complement(5273203..5273949) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase 5273949 4526968 MAV_5120 Mycobacterium avium 104 oxidoreductase YP_884237.1 5273203 R 243243 CDS YP_884238.1 118466608 4526845 complement(5273946..5274698) 1 NC_008595.1 identified by match to protein family HMM PF03328; HpcH/HpaI aldolase/citrate lyase 5274698 4526845 MAV_5121 Mycobacterium avium 104 HpcH/HpaI aldolase/citrate lyase YP_884238.1 5273946 R 243243 CDS YP_884239.1 118465989 4526131 complement(5274709..5275674) 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 5275674 4526131 MAV_5122 Mycobacterium avium 104 zinc-binding dehydrogenase YP_884239.1 5274709 R 243243 CDS YP_884240.1 118465365 4529226 complement(5275676..5276887) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 5276887 4529226 MAV_5123 Mycobacterium avium 104 cytochrome P450 YP_884240.1 5275676 R 243243 CDS YP_884241.1 118466472 4527602 complement(5276905..5277609) 1 NC_008595.1 hypothetical protein 5277609 4527602 MAV_5124 Mycobacterium avium 104 hypothetical protein YP_884241.1 5276905 R 243243 CDS YP_884242.1 118467040 4526496 complement(5277613..5278176) 1 NC_008595.1 hypothetical protein 5278176 4526496 MAV_5125 Mycobacterium avium 104 hypothetical protein YP_884242.1 5277613 R 243243 CDS YP_884243.1 118466435 4527108 complement(5278336..5279514) 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 5279514 4527108 MAV_5126 Mycobacterium avium 104 caib/baif family protein YP_884243.1 5278336 R 243243 CDS YP_884244.1 118466085 4527353 5279627..5280313 1 NC_008595.1 identified by match to protein family HMM PF04248; hypothetical protein 5280313 4527353 MAV_5128 Mycobacterium avium 104 hypothetical protein YP_884244.1 5279627 D 243243 CDS YP_884245.1 118466808 4529055 complement(5280297..5281472) 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase middle domain-containing protein 5281472 4529055 MAV_5127 Mycobacterium avium 104 acyl-CoA dehydrogenase middle domain-containing protein YP_884245.1 5280297 R 243243 CDS YP_884246.1 118463504 4527684 complement(5281481..5282401) 1 NC_008595.1 identified by match to protein family HMM PF00296; hypothetical protein 5282401 4527684 MAV_5129 Mycobacterium avium 104 hypothetical protein YP_884246.1 5281481 R 243243 CDS YP_884247.1 118462770 4527267 complement(5282407..5283300) 1 NC_008595.1 hypothetical protein 5283300 4527267 MAV_5130 Mycobacterium avium 104 hypothetical protein YP_884247.1 5282407 R 243243 CDS YP_884248.1 118463884 4530561 5283435..5283908 1 NC_008595.1 hypothetical protein 5283908 4530561 MAV_5131 Mycobacterium avium 104 hypothetical protein YP_884248.1 5283435 D 243243 CDS YP_884249.1 118465774 4526909 5283981..5284799 1 NC_008595.1 identified by match to protein family HMM PF03758; senescence marker protein-30 (SMP-30) 5284799 4526909 MAV_5132 Mycobacterium avium 104 senescence marker protein-30 (SMP-30) YP_884249.1 5283981 D 243243 CDS YP_884250.1 118464902 4530737 5284819..5285637 1 NC_008595.1 hypothetical protein 5285637 4530737 MAV_5133 Mycobacterium avium 104 hypothetical protein YP_884250.1 5284819 D 243243 CDS YP_884251.1 118466492 4525575 5285690..5286241 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5286241 4525575 MAV_5134 Mycobacterium avium 104 TetR family transcriptional regulator YP_884251.1 5285690 D 243243 CDS YP_884252.1 118466279 4527832 complement(5286255..5287595) 1 NC_008595.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD linked oxidase 5287595 4527832 MAV_5135 Mycobacterium avium 104 FAD linked oxidase YP_884252.1 5286255 R 243243 CDS YP_884253.1 118462582 4530202 complement(5287617..5288357) 1 NC_008595.1 identified by match to protein family HMM PF00106; 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 5288357 4530202 MAV_5136 Mycobacterium avium 104 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase YP_884253.1 5287617 R 243243 CDS YP_884254.1 118467151 4527582 complement(5288375..5289475) 1 NC_008595.1 identified by match to protein family HMM PF01113; match to protein family HMM PF03447; homoserine dehydrogenase 5289475 4527582 MAV_5137 Mycobacterium avium 104 homoserine dehydrogenase YP_884254.1 5288375 R 243243 CDS YP_884255.1 118463644 4528546 complement(5289593..5290228) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5290228 4528546 MAV_5138 Mycobacterium avium 104 TetR family transcriptional regulator YP_884255.1 5289593 R 243243 CDS YP_884256.1 118463388 4528015 5290387..5290512 1 NC_008595.1 hypothetical protein 5290512 4528015 MAV_5139 Mycobacterium avium 104 hypothetical protein YP_884256.1 5290387 D 243243 CDS YP_884257.1 118465117 4530469 complement(5290533..5291957) 1 NC_008595.1 identified by match to protein family HMM PF02233; NAD(P) transhydrogenase beta subunit 5291957 4530469 MAV_5140 Mycobacterium avium 104 NAD(P) transhydrogenase beta subunit YP_884257.1 5290533 R 243243 CDS YP_884258.1 118464368 4530511 complement(5291954..5292271) 1 NC_008595.1 PntAB protein 5292271 4530511 MAV_5141 Mycobacterium avium 104 PntAB protein YP_884258.1 5291954 R 243243 CDS YP_884259.1 118465844 4530637 complement(5292272..5293369) 1 NC_008595.1 identified by match to protein family HMM PF01262; match to protein family HMM PF05222; alanine dehydrogenase/pyridine nucleotide transhydrogenase 5293369 4530637 MAV_5142 Mycobacterium avium 104 alanine dehydrogenase/pyridine nucleotide transhydrogenase YP_884259.1 5292272 R 243243 CDS YP_884260.1 118464866 4530702 complement(5293511..5293972) 1 NC_008595.1 identified by match to protein family HMM PF07080; response regulator receiver domain-containing protein 5293972 4530702 MAV_5143 Mycobacterium avium 104 response regulator receiver domain-containing protein YP_884260.1 5293511 R 243243 CDS YP_884261.1 118462393 4525936 5294080..5295312 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5295312 4525936 MAV_5144 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884261.1 5294080 D 243243 CDS YP_884262.1 118462955 4526323 5295305..5296135 1 NC_008595.1 phosphotyrosine protein phosphatase ptpb 5296135 4526323 MAV_5145 Mycobacterium avium 104 phosphotyrosine protein phosphatase ptpb YP_884262.1 5295305 D 243243 CDS YP_884263.1 118463535 4526841 complement(5296155..5297009) 1 NC_008595.1 identified by match to protein family HMM PF00106; peroxisomal multifunctional enzyme type 2 5297009 4526841 MAV_5146 Mycobacterium avium 104 peroxisomal multifunctional enzyme type 2 YP_884263.1 5296155 R 243243 CDS YP_884264.1 118464085 4528398 complement(5297077..5298498) 1 NC_008595.1 identified by match to protein family HMM PF00171; fatty aldehyde dehydrogenase 5298498 4528398 MAV_5147 Mycobacterium avium 104 fatty aldehyde dehydrogenase YP_884264.1 5297077 R 243243 CDS YP_884265.1 118465380 4529671 complement(5298619..5300169) 1 NC_008595.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; cell envelope-related function transcriptional attenuator 5300169 4529671 MAV_5148 Mycobacterium avium 104 cell envelope-related function transcriptional attenuator YP_884265.1 5298619 R 243243 CDS YP_884266.1 118465946 4527942 complement(5300244..5301185) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 5301185 4527942 MAV_5149 Mycobacterium avium 104 methyltransferase, putative, family protein YP_884266.1 5300244 R 243243 CDS YP_884267.1 118466498 4525581 complement(5301217..5302158) 1 NC_008595.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027; methyltransferase, putative, family protein 5302158 4525581 MAV_5150 Mycobacterium avium 104 methyltransferase, putative, family protein YP_884267.1 5301217 R 243243 CDS YP_884268.1 118467067 4526445 complement(5302235..5302870) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5302870 4526445 MAV_5151 Mycobacterium avium 104 TetR family transcriptional regulator YP_884268.1 5302235 R 243243 CDS YP_884269.1 118466869 4529821 complement(5302873..5303859) 1 NC_008595.1 identified by match to protein family HMM PF02678; match to protein family HMM PF05726; chromosome condensation protein 5303859 4529821 MAV_5152 Mycobacterium avium 104 chromosome condensation protein YP_884269.1 5302873 R 243243 CDS YP_884270.1 118464545 4530415 complement(5303985..5304533) 1 NC_008595.1 identified by match to protein family HMM PF00210; starvation-induced DNA protecting protein 5304533 4530415 MAV_5153 Mycobacterium avium 104 starvation-induced DNA protecting protein YP_884270.1 5303985 R 243243 CDS YP_884271.1 118467038 4526494 complement(5304622..5305536) 1 NC_008595.1 hypothetical protein 5305536 4526494 MAV_5154 Mycobacterium avium 104 hypothetical protein YP_884271.1 5304622 R 243243 CDS YP_884272.1 118465210 4529847 5305597..5305998 1 NC_008595.1 hypothetical protein 5305998 4529847 MAV_5155 Mycobacterium avium 104 hypothetical protein YP_884272.1 5305597 D 243243 CDS YP_884273.1 118462390 4525933 complement(5306001..5306381) 1 NC_008595.1 identified by match to protein family HMM PF04248; hypothetical protein 5306381 4525933 MAV_5156 Mycobacterium avium 104 hypothetical protein YP_884273.1 5306001 R 243243 CDS YP_884274.1 118463099 4528922 complement(5306604..5307623) 1 NC_008595.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; 3-beta hydroxysteroid dehydrogenase/isomerase 5307623 4528922 MAV_5157 Mycobacterium avium 104 3-beta hydroxysteroid dehydrogenase/isomerase YP_884274.1 5306604 R 243243 CDS YP_884275.1 118464206 4526886 complement(5307620..5308126) 1 NC_008595.1 hypothetical protein 5308126 4526886 MAV_5158 Mycobacterium avium 104 hypothetical protein YP_884275.1 5307620 R 243243 CDS YP_884276.2 161579556 4529639 5308255..5308770 1 NC_008595.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 5308770 msrA 4529639 msrA Mycobacterium avium 104 methionine sulfoxide reductase A YP_884276.2 5308255 D 243243 CDS YP_884277.1 118465972 4528191 complement(5308783..5310099) 1 NC_008595.1 identified by match to protein family HMM PF00067; cytochrome P450 monooxygenase 5310099 4528191 MAV_5160 Mycobacterium avium 104 cytochrome P450 monooxygenase YP_884277.1 5308783 R 243243 CDS YP_884278.1 118464126 4526297 5310239..5310844 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5310844 4526297 MAV_5161 Mycobacterium avium 104 TetR family transcriptional regulator YP_884278.1 5310239 D 243243 CDS YP_884279.1 118465426 4529975 5310951..5311163 1 NC_008595.1 identified by match to protein family HMM PF03459; match to protein family HMM TIGR00638; molybdenum-binding protein 5311163 4529975 MAV_5162 Mycobacterium avium 104 molybdenum-binding protein YP_884279.1 5310951 D 243243 CDS YP_884280.1 118464795 4526719 complement(5311241..5312131) 1 NC_008595.1 identified by match to protein family HMM PF00561; alpha/beta hydrolase 5312131 4526719 MAV_5163 Mycobacterium avium 104 alpha/beta hydrolase YP_884280.1 5311241 R 243243 CDS YP_884281.1 118464848 4527964 complement(5312161..5313390) 1 NC_008595.1 hypothetical protein 5313390 4527964 MAV_5164 Mycobacterium avium 104 hypothetical protein YP_884281.1 5312161 R 243243 CDS YP_884282.1 118465543 4530019 5313425..5313994 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5313994 4530019 MAV_5165 Mycobacterium avium 104 TetR family transcriptional regulator YP_884282.1 5313425 D 243243 CDS YP_884283.1 118467163 4527595 5313991..5315103 1 NC_008595.1 hypothetical protein 5315103 4527595 MAV_5166 Mycobacterium avium 104 hypothetical protein YP_884283.1 5313991 D 243243 CDS YP_884284.1 118466892 4528405 complement(5315185..5316285) 1 NC_008595.1 identified by match to protein family HMM PF00487; Fatty acid desaturase 5316285 4528405 MAV_5167 Mycobacterium avium 104 Fatty acid desaturase YP_884284.1 5315185 R 243243 CDS YP_884285.1 118463364 4529898 complement(5316298..5317392) 1 NC_008595.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF08021; oxidoreductase FAD-binding subunit 5317392 4529898 MAV_5168 Mycobacterium avium 104 oxidoreductase FAD-binding subunit YP_884285.1 5316298 R 243243 CDS YP_884286.1 118464175 4526485 5317490..5318137 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5318137 4526485 MAV_5169 Mycobacterium avium 104 TetR family transcriptional regulator YP_884286.1 5317490 D 243243 CDS YP_884287.1 118462740 4527811 complement(5318173..5318496) 1 NC_008595.1 hypothetical protein 5318496 4527811 MAV_5170 Mycobacterium avium 104 hypothetical protein YP_884287.1 5318173 R 243243 CDS YP_884288.1 118465652 4526177 complement(5318592..5319197) 1 NC_008595.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 5319197 4526177 MAV_5171 Mycobacterium avium 104 acetyltransferase, gnat family protein YP_884288.1 5318592 R 243243 CDS YP_884289.1 118465470 4526238 5319261..5321129 1 NC_008595.1 identified by match to protein family HMM PF00296; match to protein family HMM PF01590; match to protein family HMM PF03861; F420-dependent glucose-6-phosphate dehydrogenase 5321129 4526238 MAV_5172 Mycobacterium avium 104 F420-dependent glucose-6-phosphate dehydrogenase YP_884289.1 5319261 D 243243 CDS YP_884290.1 118466973 4530372 5321223..5322518 1 NC_008595.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028; acyl-CoA dehydrogenase 5322518 4530372 MAV_5173 Mycobacterium avium 104 acyl-CoA dehydrogenase YP_884290.1 5321223 D 243243 CDS YP_884291.1 118464936 4528197 complement(5322593..5323048) 1 NC_008595.1 identified by match to protein family HMM PF01575; ZbpA protein 5323048 4528197 MAV_5174 Mycobacterium avium 104 ZbpA protein YP_884291.1 5322593 R 243243 CDS YP_884292.1 118463239 4525775 5323164..5324000 1 NC_008595.1 identified by match to protein family HMM PF00561; non-haem bromoperoxidase BPO-A2 5324000 4525775 MAV_5175 Mycobacterium avium 104 non-haem bromoperoxidase BPO-A2 YP_884292.1 5323164 D 243243 CDS YP_884293.1 118463253 4525790 5324082..5324255 1 NC_008595.1 hypothetical protein 5324255 4525790 MAV_5176 Mycobacterium avium 104 hypothetical protein YP_884293.1 5324082 D 243243 CDS YP_884294.1 118466326 4528757 complement(5324256..5324657) 1 NC_008595.1 identified by match to protein family HMM PF03625; hypothetical protein 5324657 4528757 MAV_5177 Mycobacterium avium 104 hypothetical protein YP_884294.1 5324256 R 243243 CDS YP_884295.1 118462622 4526424 complement(5324704..5325006) 1 NC_008595.1 identified by match to protein family HMM PF02583; hypothetical protein 5325006 4526424 MAV_5178 Mycobacterium avium 104 hypothetical protein YP_884295.1 5324704 R 243243 CDS YP_884296.1 118463191 4527714 5325056..5325583 1 NC_008595.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; hypothetical protein 5325583 4527714 MAV_5179 Mycobacterium avium 104 hypothetical protein YP_884296.1 5325056 D 243243 CDS YP_884297.1 118465486 4527239 5325690..5326103 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 5326103 4527239 MAV_5180 Mycobacterium avium 104 MarR family transcriptional regulator YP_884297.1 5325690 D 243243 CDS YP_884298.1 118464797 4526721 5326100..5326942 1 NC_008595.1 identified by match to protein family HMM PF00005; daunorubicin ABC transporter ATPase 5326942 4526721 MAV_5181 Mycobacterium avium 104 daunorubicin ABC transporter ATPase YP_884298.1 5326100 D 243243 CDS YP_884299.1 118464908 4530743 5326932..5327750 1 NC_008595.1 identified by match to protein family HMM PF01061; drug ABC transporter membrane protein 5327750 4530743 MAV_5182 Mycobacterium avium 104 drug ABC transporter membrane protein YP_884299.1 5326932 D 243243 CDS YP_884300.1 118465788 4526101 5327985..5329052 1 NC_008595.1 identified by match to protein family HMM PF00756; antigen 85-C 5329052 4526101 MAV_5183 Mycobacterium avium 104 antigen 85-C YP_884300.1 5327985 D 243243 CDS YP_884301.1 118466686 4530428 complement(5329108..5329794) 1 NC_008595.1 identified by match to protein family HMM PF06912; hypothetical protein 5329794 4530428 MAV_5184 Mycobacterium avium 104 hypothetical protein YP_884301.1 5329108 R 243243 CDS YP_884302.1 118467284 4527086 complement(5329840..5331198) 1 NC_008595.1 trehalose synthase-fused maltokinase 5331198 4527086 MAV_5185 Mycobacterium avium 104 trehalose synthase-fused maltokinase YP_884302.1 5329840 R 243243 CDS YP_884303.1 118465148 4529238 complement(5331248..5333020) 1 NC_008595.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02456; trehalose synthase 5333020 treS 4529238 treS Mycobacterium avium 104 trehalose synthase YP_884303.1 5331248 R 243243 CDS YP_884304.1 118465668 4526740 complement(5333142..5334257) 1 NC_008595.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; trypsin 5334257 4526740 MAV_5187 Mycobacterium avium 104 trypsin YP_884304.1 5333142 R 243243 CDS YP_884305.1 118463811 4526066 5334401..5334838 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 5334838 4526066 MAV_5188 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_884305.1 5334401 D 243243 CDS YP_884306.1 118464431 4530252 5334984..5337146 1 NC_008595.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 5337146 4530252 MAV_5189 Mycobacterium avium 104 elongation factor G YP_884306.1 5334984 D 243243 CDS YP_884307.1 118462342 4525687 complement(5337165..5338823) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 5338823 4525687 MAV_5190 Mycobacterium avium 104 acyl-CoA synthetase YP_884307.1 5337165 R 243243 CDS YP_884308.1 118467230 4529787 complement(5340715..5341647) 1 NC_008595.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 5341647 4529787 MAV_5191 Mycobacterium avium 104 LysR family transcriptional regulator YP_884308.1 5340715 R 243243 CDS YP_884309.1 118466770 4530765 complement(5341705..5342457) 1 NC_008595.1 identified by match to protein family HMM PF00857; isochorismatase 5342457 4530765 MAV_5193 Mycobacterium avium 104 isochorismatase YP_884309.1 5341705 R 243243 CDS YP_884310.1 118467140 4527154 5342534..5343262 1 NC_008595.1 identified by match to protein family HMM PF03734; ErfK/YbiS/YcfS/YnhG family protein 5343262 4527154 MAV_5194 Mycobacterium avium 104 ErfK/YbiS/YcfS/YnhG family protein YP_884310.1 5342534 D 243243 CDS YP_884311.1 118466414 4526258 complement(5343374..5343973) 1 NC_008595.1 hypothetical protein 5343973 4526258 MAV_5195 Mycobacterium avium 104 hypothetical protein YP_884311.1 5343374 R 243243 CDS YP_884312.1 118462456 4525629 5344141..5345085 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 5345085 4525629 MAV_5196 Mycobacterium avium 104 zinc-binding dehydrogenase YP_884312.1 5344141 D 243243 CDS YP_884313.1 118464226 4528599 complement(5345087..5346847) 1 NC_008595.1 identified by match to protein family HMM PF01566; manganese/iron transporter 5346847 4528599 MAV_5197 Mycobacterium avium 104 manganese/iron transporter YP_884313.1 5345087 R 243243 CDS YP_884314.1 118463427 4528306 complement(5346981..5347139) 1 NC_008595.1 hypothetical protein 5347139 4528306 MAV_5198 Mycobacterium avium 104 hypothetical protein YP_884314.1 5346981 R 243243 CDS YP_884315.1 118463733 4528141 5347180..5347314 1 NC_008595.1 hypothetical protein 5347314 4528141 MAV_5199 Mycobacterium avium 104 hypothetical protein YP_884315.1 5347180 D 243243 CDS YP_884316.1 118465335 4526531 5347715..5348374 1 NC_008595.1 identified by match to protein family HMM PF01596; O-methyltransferase, family protein 3 5348374 4526531 MAV_5200 Mycobacterium avium 104 O-methyltransferase, family protein 3 YP_884316.1 5347715 D 243243 CDS YP_884317.1 118464611 4526768 complement(5348379..5350373) 1 NC_008595.1 identified by match to protein family HMM PF01757; acyltransferase 5350373 4526768 MAV_5201 Mycobacterium avium 104 acyltransferase YP_884317.1 5348379 R 243243 CDS YP_884318.1 118466438 4527111 complement(5350609..5352045) 1 NC_008595.1 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 5352045 4527111 MAV_5202 Mycobacterium avium 104 aldehyde dehydrogenase YP_884318.1 5350609 R 243243 CDS YP_884319.1 118464389 4528278 complement(5352061..5353767) 1 NC_008595.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; thiamine pyrophosphate-binding protein 5353767 4528278 MAV_5203 Mycobacterium avium 104 thiamine pyrophosphate-binding protein YP_884319.1 5352061 R 243243 CDS YP_884320.1 118465244 4528462 complement(5353768..5354907) 1 NC_008595.1 identified by match to protein family HMM PF02515; L-carnitine dehydratase/bile acid-inducible protein F 5354907 4528462 MAV_5204 Mycobacterium avium 104 L-carnitine dehydratase/bile acid-inducible protein F YP_884320.1 5353768 R 243243 CDS YP_884321.1 118465787 4526100 complement(5355027..5355935) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 5355935 4526100 MAV_5205 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_884321.1 5355027 R 243243 CDS YP_884322.1 118466689 4530431 complement(5355974..5357833) 1 NC_008595.1 identified by match to protein family HMM PF01266; cyclododecanone monooxygenase 5357833 4530431 MAV_5206 Mycobacterium avium 104 cyclododecanone monooxygenase YP_884322.1 5355974 R 243243 CDS YP_884323.1 118467256 4526091 complement(5357830..5359230) 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 5359230 4526091 MAV_5207 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_884323.1 5357830 R 243243 CDS YP_884324.1 118466874 4526692 complement(5359230..5360045) 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 5360045 4526692 MAV_5208 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_884324.1 5359230 R 243243 CDS YP_884325.1 118466890 4528403 complement(5360240..5360365) 1 NC_008595.1 hypothetical protein 5360365 4528403 MAV_5209 Mycobacterium avium 104 hypothetical protein YP_884325.1 5360240 R 243243 CDS YP_884326.1 118462311 4529629 5360355..5361932 1 NC_008595.1 identified by match to protein family HMM PF01436; hypothetical protein 5361932 4529629 MAV_5210 Mycobacterium avium 104 hypothetical protein YP_884326.1 5360355 D 243243 CDS YP_884327.1 118462689 4530617 5361932..5362681 1 NC_008595.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 5362681 4530617 MAV_5211 Mycobacterium avium 104 GntR family transcriptional regulator YP_884327.1 5361932 D 243243 CDS YP_884328.1 118463231 4528805 5362683..5364299 1 NC_008595.1 identified by match to protein family HMM PF00501; AMP-binding enzyme, putative 5364299 4528805 MAV_5212 Mycobacterium avium 104 AMP-binding enzyme, putative YP_884328.1 5362683 D 243243 CDS YP_884329.1 118464667 4528264 5364301..5365074 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 5365074 4528264 MAV_5213 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_884329.1 5364301 D 243243 CDS YP_884330.1 118467051 4526507 complement(5365083..5366225) 1 NC_008595.1 identified by match to protein family HMM PF00107; alcohol dehydrogenase B 5366225 4526507 MAV_5214 Mycobacterium avium 104 alcohol dehydrogenase B YP_884330.1 5365083 R 243243 CDS YP_884331.1 118465422 4529971 complement(5366311..5366805) 1 NC_008595.1 hypothetical protein 5366805 4529971 MAV_5215 Mycobacterium avium 104 hypothetical protein YP_884331.1 5366311 R 243243 CDS YP_884332.1 118465924 4528483 5366892..5367263 1 NC_008595.1 hypothetical protein 5367263 4528483 MAV_5216 Mycobacterium avium 104 hypothetical protein YP_884332.1 5366892 D 243243 CDS YP_884333.1 118466330 4528761 5367298..5367528 1 NC_008595.1 hypothetical protein 5367528 4528761 MAV_5217 Mycobacterium avium 104 hypothetical protein YP_884333.1 5367298 D 243243 CDS YP_884334.1 118463220 4528794 complement(5367586..5367897) 1 NC_008595.1 hypothetical protein 5367897 4528794 MAV_5218 Mycobacterium avium 104 hypothetical protein YP_884334.1 5367586 R 243243 CDS YP_884335.1 118463660 4525952 5368018..5372796 1 NC_008595.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; ATPase P 5372796 4525952 MAV_5219 Mycobacterium avium 104 ATPase P YP_884335.1 5368018 D 243243 CDS YP_884336.1 118464228 4528601 complement(5372803..5374353) 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 5374353 4528601 MAV_5220 Mycobacterium avium 104 acyl-CoA synthetase YP_884336.1 5372803 R 243243 CDS YP_884337.1 118464006 4529268 complement(5374358..5375296) 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 5375296 4529268 MAV_5221 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_884337.1 5374358 R 243243 CDS YP_884338.1 118462552 4530553 complement(5376276..5377682) 1 NC_008595.1 hypothetical protein 5377682 4530553 MAV_5223 Mycobacterium avium 104 hypothetical protein YP_884338.1 5376276 R 243243 CDS YP_884339.1 118463259 4528124 complement(5377685..5378875) 1 NC_008595.1 hypothetical protein 5378875 4528124 MAV_5224 Mycobacterium avium 104 hypothetical protein YP_884339.1 5377685 R 243243 CDS YP_884340.1 118466862 4529814 complement(5378903..5379667) 1 NC_008595.1 identified by match to protein family HMM PF00106; DltE protein 5379667 4529814 MAV_5225 Mycobacterium avium 104 DltE protein YP_884340.1 5378903 R 243243 CDS YP_884341.1 118464382 4528271 complement(5379819..5380772) 1 NC_008595.1 hypothetical protein 5380772 4528271 MAV_5226 Mycobacterium avium 104 hypothetical protein YP_884341.1 5379819 R 243243 CDS YP_884342.1 118463757 4528001 5380884..5381477 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator, putative 5381477 4528001 MAV_5227 Mycobacterium avium 104 TetR family transcriptional regulator, putative YP_884342.1 5380884 D 243243 CDS YP_884343.1 118462861 4527088 5381519..5382904 1 NC_008595.1 identified by match to protein family HMM PF00211; match to protein family HMM PF00561; hydrolase, alpha/beta hydrolase family protein 5382904 4527088 MAV_5228 Mycobacterium avium 104 hydrolase, alpha/beta hydrolase family protein YP_884343.1 5381519 D 243243 CDS YP_884344.1 118462307 4525652 5383030..5383776 1 NC_008595.1 identified by match to protein family HMM PF01209; methyltransferase type 11 5383776 4525652 MAV_5229 Mycobacterium avium 104 methyltransferase type 11 YP_884344.1 5383030 D 243243 CDS YP_884345.1 118467275 4527077 complement(5383792..5384250) 1 NC_008595.1 hypothetical protein 5384250 4527077 MAV_5230 Mycobacterium avium 104 hypothetical protein YP_884345.1 5383792 R 243243 CDS YP_884346.1 118463541 4526808 complement(5384909..5385106) 1 NC_008595.1 hypothetical protein 5385106 4526808 MAV_5232 Mycobacterium avium 104 hypothetical protein YP_884346.1 5384909 R 243243 CDS YP_884347.1 118465213 4529850 complement(5385193..5386038) 1 NC_008595.1 identified by match to protein family HMM PF01370; 3-alpha-hydroxysteroid dehydrogenase 5386038 4529850 MAV_5233 Mycobacterium avium 104 3-alpha-hydroxysteroid dehydrogenase YP_884347.1 5385193 R 243243 CDS YP_884348.1 118466013 4528458 complement(5386043..5386807) 1 NC_008595.1 hypothetical protein 5386807 4528458 MAV_5234 Mycobacterium avium 104 hypothetical protein YP_884348.1 5386043 R 243243 CDS YP_884349.1 118464504 4525547 complement(5386861..5387727) 1 NC_008595.1 transcriptional regulator 5387727 4525547 MAV_5235 Mycobacterium avium 104 transcriptional regulator YP_884349.1 5386861 R 243243 CDS YP_884350.1 118463916 4525847 5387843..5388895 1 NC_008595.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase 5388895 4525847 MAV_5236 Mycobacterium avium 104 zinc-binding dehydrogenase YP_884350.1 5387843 D 243243 CDS YP_884351.1 118466493 4525576 5388892..5389308 1 NC_008595.1 identified by match to protein family HMM TIGR02246; hypothetical protein 5389308 4525576 MAV_5237 Mycobacterium avium 104 hypothetical protein YP_884351.1 5388892 D 243243 CDS YP_884352.1 118465619 4528735 5389305..5390123 1 NC_008595.1 identified by match to protein family HMM PF00106; oxidoreductase, short chain dehydrogenase/reductase 5390123 4528735 MAV_5238 Mycobacterium avium 104 oxidoreductase, short chain dehydrogenase/reductase YP_884352.1 5389305 D 243243 CDS YP_884353.1 118462247 4526933 5390366..5391649 1 NC_008595.1 identified by match to protein family HMM PF01699; sodium/calcium exchanger family protein 5391649 4526933 MAV_5239 Mycobacterium avium 104 sodium/calcium exchanger family protein YP_884353.1 5390366 D 243243 CDS YP_884354.1 118466805 4529051 5391694..5392521 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; short chain dehydrogenase 5392521 4529051 MAV_5240 Mycobacterium avium 104 short chain dehydrogenase YP_884354.1 5391694 D 243243 CDS YP_884355.1 118464250 4527435 complement(5392576..5394171) 1 NC_008595.1 monooxygenase 5394171 4527435 MAV_5241 Mycobacterium avium 104 monooxygenase YP_884355.1 5392576 R 243243 CDS YP_884356.1 118463417 4530054 5394266..5394823 1 NC_008595.1 identified by match to protein family HMM PF01243; pyridoxamine 5'-phosphate oxidase 5394823 4530054 MAV_5242 Mycobacterium avium 104 pyridoxamine 5'-phosphate oxidase YP_884356.1 5394266 D 243243 CDS YP_884357.1 118465425 4529974 complement(5394824..5395294) 1 NC_008595.1 hypothetical protein 5395294 4529974 MAV_5243 Mycobacterium avium 104 hypothetical protein YP_884357.1 5394824 R 243243 CDS YP_884358.1 118464565 4530784 5395404..5396225 1 NC_008595.1 identified by match to protein family HMM PF00106; cholesterol oxidase 5396225 4530784 MAV_5244 Mycobacterium avium 104 cholesterol oxidase YP_884358.1 5395404 D 243243 CDS YP_884359.1 118463247 4525783 5396311..5396523 1 NC_008595.1 identified by match to protein family HMM PF00403; hypothetical protein 5396523 4525783 MAV_5245 Mycobacterium avium 104 hypothetical protein YP_884359.1 5396311 D 243243 CDS YP_884360.1 118463890 4530567 5396520..5398808 1 NC_008595.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 5398808 4530567 MAV_5246 Mycobacterium avium 104 copper-translocating P-type ATPase YP_884360.1 5396520 D 243243 CDS YP_884361.1 118465639 4526164 5400592..5401401 1 NC_008595.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase 5401401 4526164 MAV_5248 Mycobacterium avium 104 polysaccharide deacetylase YP_884361.1 5400592 D 243243 CDS YP_884362.1 118464341 4529143 complement(5401408..5401827) 1 NC_008595.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 5401827 4529143 MAV_5249 Mycobacterium avium 104 MarR family transcriptional regulator YP_884362.1 5401408 R 243243 CDS YP_884363.1 118464656 4528253 5401939..5402883 1 NC_008595.1 LpqP protein 5402883 4528253 MAV_5250 Mycobacterium avium 104 LpqP protein YP_884363.1 5401939 D 243243 CDS YP_884364.1 118462549 4530550 5402930..5404240 1 NC_008595.1 identified by similarity to SP:O94091; match to protein family HMM PF03583; secretory lipase 5404240 4530550 MAV_5251 Mycobacterium avium 104 secretory lipase YP_884364.1 5402930 D 243243 CDS YP_884365.1 118463213 4527540 5404317..5404877 1 NC_008595.1 hypothetical protein 5404877 4527540 MAV_5252 Mycobacterium avium 104 hypothetical protein YP_884365.1 5404317 D 243243 CDS YP_884366.1 118466794 4529352 complement(5404920..5405528) 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5405528 4529352 MAV_5253 Mycobacterium avium 104 TetR family transcriptional regulator YP_884366.1 5404920 R 243243 CDS YP_884367.1 118466115 4529748 5405600..5406430 1 NC_008595.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta hydrolase family protein 5406430 4529748 MAV_5254 Mycobacterium avium 104 hydrolase, alpha/beta hydrolase family protein YP_884367.1 5405600 D 243243 CDS YP_884368.1 118466839 4526948 5406506..5407267 1 NC_008595.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 5407267 4526948 MAV_5255 Mycobacterium avium 104 NAD dependent epimerase/dehydratase YP_884368.1 5406506 D 243243 CDS YP_884369.1 118465747 4525710 5407354..5408994 1 NC_008595.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 5408994 4525710 MAV_5257 Mycobacterium avium 104 acyl-CoA synthetase YP_884369.1 5407354 D 243243 CDS YP_884370.1 118464993 4526259 complement(5408933..5409583) 1 NC_008595.1 hypothetical protein 5409583 4526259 MAV_5256 Mycobacterium avium 104 hypothetical protein YP_884370.1 5408933 R 243243 CDS YP_884371.1 118463463 4525516 complement(5409580..5410011) 1 NC_008595.1 identified by match to protein family HMM PF01796; hypothetical protein 5410011 4525516 MAV_5258 Mycobacterium avium 104 hypothetical protein YP_884371.1 5409580 R 243243 CDS YP_884372.1 118463855 4529954 complement(5410008..5411174) 1 NC_008595.1 hypothetical protein 5411174 4529954 MAV_5259 Mycobacterium avium 104 hypothetical protein YP_884372.1 5410008 R 243243 CDS YP_884373.1 118464097 4525858 complement(5411164..5411493) 1 NC_008595.1 hypothetical protein 5411493 4525858 MAV_5260 Mycobacterium avium 104 hypothetical protein YP_884373.1 5411164 R 243243 CDS YP_884374.1 118466158 4528780 complement(5411495..5413825) 1 NC_008595.1 identified by match to protein family HMM PF02515; caib/baif family protein 5413825 4528780 MAV_5261 Mycobacterium avium 104 caib/baif family protein YP_884374.1 5411495 R 243243 CDS YP_884375.1 118466842 4526951 complement(5413828..5415201) 1 NC_008595.1 identified by match to protein family HMM PF04909; amidohydrolase 5415201 4526951 MAV_5262 Mycobacterium avium 104 amidohydrolase YP_884375.1 5413828 R 243243 CDS YP_884376.1 118466664 4526614 5415443..5416447 1 NC_008595.1 identified by match to protein family HMM PF00356; LacI family transcriptional regulator 5416447 4526614 MAV_5263 Mycobacterium avium 104 LacI family transcriptional regulator YP_884376.1 5415443 D 243243 CDS YP_884377.1 118463243 4525779 complement(5416451..5416864) 1 NC_008595.1 identified by match to protein family HMM PF01796; acyl dehydratase 5416864 4525779 MAV_5264 Mycobacterium avium 104 acyl dehydratase YP_884377.1 5416451 R 243243 CDS YP_884378.1 118463886 4530563 complement(5416870..5418084) 1 NC_008595.1 nonspecific lipid-transfer protein 5418084 4530563 MAV_5265 Mycobacterium avium 104 nonspecific lipid-transfer protein YP_884378.1 5416870 R 243243 CDS YP_884379.1 118464606 4530117 5420513..5421097 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5421097 4530117 MAV_5267 Mycobacterium avium 104 TetR family transcriptional regulator YP_884379.1 5420513 D 243243 CDS YP_884380.1 118462894 4527501 5421175..5422272 1 NC_008595.1 hypothetical protein 5422272 4527501 MAV_5268 Mycobacterium avium 104 hypothetical protein YP_884380.1 5421175 D 243243 CDS YP_884381.1 118462281 4529286 5422269..5423441 1 NC_008595.1 hypothetical protein 5423441 4529286 MAV_5269 Mycobacterium avium 104 hypothetical protein YP_884381.1 5422269 D 243243 CDS YP_884382.1 118467329 4526967 5423458..5424525 1 NC_008595.1 identified by match to protein family HMM PF02641; hypothetical protein 5424525 4526967 MAV_5270 Mycobacterium avium 104 hypothetical protein YP_884382.1 5423458 D 243243 CDS YP_884383.1 118466616 4526854 complement(5424527..5425420) 1 NC_008595.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; fructose-1,6-bisphosphate aldolase 5425420 4526854 MAV_5271 Mycobacterium avium 104 fructose-1,6-bisphosphate aldolase YP_884383.1 5424527 R 243243 CDS YP_884384.1 118463996 4529258 5425868..5426245 1 NC_008595.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; anti-anti-sigma factor 5426245 4529258 MAV_5272 Mycobacterium avium 104 anti-anti-sigma factor YP_884384.1 5425868 D 243243 CDS YP_884385.1 118464559 4530778 complement(5426302..5427387) 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 5427387 4530778 MAV_5273 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_884385.1 5426302 R 243243 CDS YP_884386.1 118465716 4527451 complement(5427384..5428520) 1 NC_008595.1 hypothetical protein 5428520 4527451 MAV_5274 Mycobacterium avium 104 hypothetical protein YP_884386.1 5427384 R 243243 CDS YP_884387.1 118466221 4528901 5428646..5429266 1 NC_008595.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 5429266 4528901 MAV_5275 Mycobacterium avium 104 TetR family transcriptional regulator YP_884387.1 5428646 D 243243 CDS YP_884388.1 118466811 4529058 5429369..5430505 1 NC_008595.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 5430505 4529058 MAV_5276 Mycobacterium avium 104 phosphotransferase enzyme family protein YP_884388.1 5429369 D 243243 CDS YP_884389.1 118462826 4528640 5430652..5432418 1 NC_008595.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07908; match to protein family HMM PF07969; amidohydrolase 5432418 4528640 MAV_5277 Mycobacterium avium 104 amidohydrolase YP_884389.1 5430652 D 243243 CDS YP_884390.1 118463382 4528960 5432433..5433779 1 NC_008595.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 5433779 4528960 MAV_5278 Mycobacterium avium 104 Rieske (2Fe-2S) domain-containing protein YP_884390.1 5432433 D 243243 CDS YP_884391.1 118463988 4530347 5434000..5434224 1 NC_008595.1 hypothetical protein 5434224 4530347 MAV_5279 Mycobacterium avium 104 hypothetical protein YP_884391.1 5434000 D 243243 CDS YP_884392.1 118465118 4530470 complement(5434240..5434896) 1 NC_008595.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF04545; two-component system response regulator 5434896 4530470 MAV_5280 Mycobacterium avium 104 two-component system response regulator YP_884392.1 5434240 R 243243 CDS YP_884393.1 118465632 4528749 complement(5434893..5436113) 1 NC_008595.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase domain-containing protein 5436113 4528749 MAV_5281 Mycobacterium avium 104 histidine kinase domain-containing protein YP_884393.1 5434893 R 243243 CDS YP_884394.1 118465239 4525610 5436246..5436626 1 NC_008595.1 hypothetical protein 5436626 4525610 MAV_5282 Mycobacterium avium 104 hypothetical protein YP_884394.1 5436246 D 243243 CDS YP_884395.1 118466652 4528090 5436619..5439477 1 NC_008595.1 identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833; membrane protein, MmpL family protein 5439477 4528090 MAV_5284 Mycobacterium avium 104 membrane protein, MmpL family protein YP_884395.1 5436619 D 243243 CDS YP_884396.1 118464400 4530794 complement(5443680..5445167) 1 NC_008595.1 identified by match to protein family HMM PF05108; hypothetical protein 5445167 4530794 MAV_5285 Mycobacterium avium 104 hypothetical protein YP_884396.1 5443680 R 243243 CDS YP_884397.1 118463689 4528536 complement(5445170..5446036) 1 NC_008595.1 identified by match to protein family HMM PF01464; transglycosylase 5446036 4528536 MAV_5286 Mycobacterium avium 104 transglycosylase YP_884397.1 5445170 R 243243 CDS YP_884398.1 118465693 4530315 complement(5446287..5447207) 1 NC_008595.1 hypothetical protein 5447207 4530315 MAV_5287 Mycobacterium avium 104 hypothetical protein YP_884398.1 5446287 R 243243 CDS YP_884399.1 118465280 4529315 complement(5447317..5448576) 1 NC_008595.1 hypothetical protein 5448576 4529315 MAV_5288 Mycobacterium avium 104 hypothetical protein YP_884399.1 5447317 R 243243 CDS YP_884400.1 118465266 4527287 5448992..5449171 1 NC_008595.1 hypothetical protein 5449171 4527287 MAV_5289 Mycobacterium avium 104 hypothetical protein YP_884400.1 5448992 D 243243 CDS YP_884401.1 118462437 4528300 complement(5450022..5450675) 1 NC_008595.1 hypothetical protein 5450675 4528300 MAV_5290 Mycobacterium avium 104 hypothetical protein YP_884401.1 5450022 R 243243 CDS YP_884402.1 118467290 4527248 complement(5450889..5451107) 1 NC_008595.1 hypothetical protein 5451107 4527248 MAV_5291 Mycobacterium avium 104 hypothetical protein YP_884402.1 5450889 R 243243 CDS YP_884403.1 118466699 4529706 complement(5451347..5453314) 1 NC_008595.1 identified by match to protein family HMM PF06259; hypothetical protein 5453314 4529706 MAV_5292 Mycobacterium avium 104 hypothetical protein YP_884403.1 5451347 R 243243 CDS YP_884404.1 118465581 4527128 complement(5453361..5453870) 1 NC_008595.1 hypothetical protein 5453870 4527128 MAV_5293 Mycobacterium avium 104 hypothetical protein YP_884404.1 5453361 R 243243 CDS YP_884405.1 118465833 4525505 complement(5453895..5455337) 1 NC_008595.1 identified by match to protein family HMM PF01743; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR02692; tRNA adenylyltransferase 5455337 4525505 MAV_5294 Mycobacterium avium 104 tRNA adenylyltransferase YP_884405.1 5453895 R 243243 CDS YP_884406.1 118464187 4529298 5455508..5456875 1 NC_008595.1 hypothetical protein 5456875 4529298 MAV_5295 Mycobacterium avium 104 hypothetical protein YP_884406.1 5455508 D 243243 CDS YP_884407.1 118462483 4530679 5457278..5458027 1 NC_008595.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 5458027 4530679 MAV_5296 Mycobacterium avium 104 MutT/nudix family protein YP_884407.1 5457278 D 243243 CDS YP_884408.1 118465424 4529973 5460422..5464057 1 NC_008595.1 identified by match to protein family HMM PF03023; virulence factor mvin family protein 5464057 4529973 MAV_5298 Mycobacterium avium 104 virulence factor mvin family protein YP_884408.1 5460422 D 243243 CDS YP_884409.1 118463700 4530587 5464137..5464724 1 NC_008595.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase; RNA polymerase sigma factor SigM 5464724 4530587 MAV_5299 Mycobacterium avium 104 RNA polymerase sigma factor SigM YP_884409.1 5464137 D 243243 CDS YP_884410.1 118463922 4528102 5464785..5465549 1 NC_008595.1 hypothetical protein 5465549 4528102 MAV_5300 Mycobacterium avium 104 hypothetical protein YP_884410.1 5464785 D 243243 CDS YP_884411.1 118465167 4528657 5465563..5466663 1 NC_008595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 5466663 trxB 4528657 trxB Mycobacterium avium 104 thioredoxin-disulfide reductase YP_884411.1 5465563 D 243243 CDS YP_884412.1 118465727 4527462 5466660..5467013 1 NC_008595.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 5467013 trx 4527462 trx Mycobacterium avium 104 thioredoxin YP_884412.1 5466660 D 243243 CDS YP_884413.1 118465835 4525507 5467147..5468367 1 NC_008595.1 identified by match to protein family HMM PF01471; match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 5468367 4525507 MAV_5303 Mycobacterium avium 104 N-acetylmuramoyl-L-alanine amidase YP_884413.1 5467147 D 243243 CDS YP_884414.1 118464843 4527959 complement(5468401..5469132) 1 NC_008595.1 hypothetical protein 5469132 4527959 MAV_5304 Mycobacterium avium 104 hypothetical protein YP_884414.1 5468401 R 243243 CDS YP_884415.1 118462282 4529287 5469204..5469380 1 NC_008595.1 hypothetical protein 5469380 4529287 MAV_5305 Mycobacterium avium 104 hypothetical protein YP_884415.1 5469204 D 243243 CDS YP_884416.1 118464564 4530783 complement(5469398..5470384) 1 NC_008595.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB-like partition proteins 5470384 4530783 MAV_5306 Mycobacterium avium 104 ParB-like partition proteins YP_884416.1 5469398 R 243243 CDS YP_884417.1 118463688 4528535 complement(5470420..5471517) 1 NC_008595.1 identified by match to protein family HMM PF01656; CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein 5471517 4528535 MAV_5307 Mycobacterium avium 104 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein YP_884417.1 5470420 R 243243 CDS YP_884418.1 118462827 4528641 complement(5471514..5472251) 1 NC_008595.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 5472251 gidB 4528641 gidB Mycobacterium avium 104 16S rRNA methyltransferase GidB YP_884418.1 5471514 R 243243 CDS YP_884419.1 118467028 4526540 complement(5472340..5472891) 1 NC_008595.1 identified by match to protein family HMM PF01424; R3H domain-containing protein 5472891 4526540 MAV_5309 Mycobacterium avium 104 R3H domain-containing protein YP_884419.1 5472340 R 243243 CDS YP_884420.1 118466815 4527380 complement(5472973..5474025) 1 NC_008595.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 5474025 4527380 MAV_5310 Mycobacterium avium 104 inner membrane protein translocase component YidC YP_884420.1 5472973 R 243243 CDS YP_884421.1 118465987 4526129 complement(5474018..5474365) 1 NC_008595.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 5474365 4526129 MAV_5311 Mycobacterium avium 104 hypothetical protein YP_884421.1 5474018 R 243243 CDS YP_884422.1 118462642 4529383 complement(5474362..5474721) 1 NC_008595.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 5474721 rnpA 4529383 rnpA Mycobacterium avium 104 ribonuclease P YP_884422.1 5474362 R 243243 CDS YP_884423.1 118463174 4529876 complement(5474743..5474886) 1 NC_008595.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 5474886 rpmH 4529876 rpmH Mycobacterium avium 104 50S ribosomal protein L34 YP_884423.1 5474743 R 243243 CDS