-- dump date 20140619_154516 -- class Genbank::CDS -- table cds_note -- id note YP_001285946.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001285947.1 binds the polymerase to DNA and acts as a sliding clamp YP_001285948.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001285949.1 Mapped to H37Rv Rv0004 YP_001285950.1 negatively supercoils closed circular double-stranded DNA YP_001285951.1 negatively supercoils closed circular double-stranded DNA YP_001285952.1 Mapped to H37Rv Rv0007 YP_001285953.1 Mapped to H37Rv Rv0008c YP_001285954.1 Mapped to H37Rv Rv0009 YP_001285955.1 Mapped to H37Rv Rv0010c YP_001285956.1 integral membrane protein involved in inhibition of the Z-ring formation YP_001285957.1 Mapped to H37Rv Rv0012 YP_001285958.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001285959.1 Mapped to H37Rv Rv0014c YP_001285960.1 Mapped to H37Rv Rv0015c YP_001285961.1 Mapped to H37Rv Rv0016c YP_001285962.1 Mapped to H37Rv Rv0017c YP_001285963.1 Mapped to H37Rv Rv0018c YP_001285964.1 Mapped to H37Rv Rv0019c YP_001285965.1 Mapped to H37Rv Rv0020c YP_001285966.1 Mapped to H37Rv Rv0021c YP_001285967.1 Mapped to H37Rv Rv0022c YP_001285968.1 Mapped to H37Rv Rv0023 YP_001285969.1 Mapped to H37Rv Rv0024 YP_001285970.1 Mapped to H37Rv Rv0025 YP_001285971.1 Mapped to H37Rv Rv0026 YP_001285972.1 Mapped to H37Rv Rv0027 YP_001285973.1 Mapped to H37Rv Rv0028 YP_001285974.1 Mapped to H37Rv Rv0029 YP_001285975.1 Mapped to H37Rv Rv0029 YP_001285976.1 Mapped to H37Rv Rv0032 YP_001285977.1 Mapped to H37Rv Rv0033 YP_001285978.1 Mapped to H37Rv Rv0034 YP_001285979.1 Mapped to H37Rv Rv0035 YP_001285980.1 Mapped to H37Rv Rv0036c YP_001285981.1 Mapped to H37Rv Rv0037c YP_001285982.1 Mapped to H37Rv Rv0038 YP_001285983.1 Mapped to H37Rv Rv0039c YP_001285984.1 Mapped to H37Rv Rv0040c YP_001285985.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001285986.1 Mapped to H37Rv Rv0042c YP_001285987.1 Mapped to H37Rv Rv0043c YP_001285988.1 Mapped to H37Rv Rv0044c YP_001285989.1 Mapped to H37Rv Rv0045c YP_001285990.1 Mapped to H37Rv Rv0046c YP_001285991.1 Mapped to H37Rv Rv0047c YP_001285992.1 Mapped to H37Rv Rv0048c YP_001285993.1 Mapped to H37Rv Rv0049 YP_001285994.1 Mapped to H37Rv Rv0050 YP_001285995.1 Mapped to H37Rv Rv0051 YP_001285996.1 Mapped to H37Rv Rv0052 YP_001285997.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001285998.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001285999.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001286000.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001286001.1 Mapped to H37Rv Rv0057 YP_001286002.1 unwinds double stranded DNA; these Mycobacterial enzymes appear to contain inteins YP_001286003.1 Mapped to H37Rv Rv0059 YP_001286004.1 Mapped to H37Rv Rv0060 YP_001286005.1 Mapped to H37Rv Rv0060 YP_001286006.1 Mapped to H37Rv Rv0062 YP_001286007.1 Mapped to H37Rv Rv0063 YP_001286008.1 Mapped to H37Rv Rv0064 YP_001286009.1 Mapped to H37Rv Rv0064 YP_001286010.1 Mapped to H37Rv Rv0065 YP_001286011.1 Mapped to H37Rv Rv0066c YP_001286012.1 Mapped to H37Rv Rv0067c YP_001286013.1 Mapped to H37Rv Rv0068 YP_001286014.1 Mapped to H37Rv Rv0069c YP_001286015.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001286016.1 Mapped to H37Rv Rv0071 YP_001286017.1 Mapped to H37Rv Rv0072 YP_001286018.1 Mapped to H37Rv Rv0073 YP_001286019.1 Mapped to H37Rv Rv0074 YP_001286020.1 Mapped to H37Rv Rv0075 YP_001286021.1 Mapped to H37Rv Rv0076c YP_001286022.1 Mapped to H37Rv Rv0077c YP_001286023.1 Mapped to H37Rv Rv0078 YP_001286024.1 Mapped to H37Rv Rv0078A YP_001286025.1 Mapped to H37Rv Rv0079 YP_001286026.1 Mapped to H37Rv Rv0080 YP_001286027.1 Mapped to H37Rv Rv0081 YP_001286028.1 Mapped to H37Rv Rv0082 YP_001286029.1 Mapped to H37Rv Rv0083 YP_001286030.1 Mapped to H37Rv Rv0084 YP_001286031.1 Mapped to H37Rv Rv0085 YP_001286032.1 Mapped to H37Rv Rv0086 YP_001286033.1 Mapped to H37Rv Rv0087 YP_001286034.1 Mapped to H37Rv Rv0088 YP_001286035.1 Mapped to H37Rv Rv0089 YP_001286036.1 Mapped to H37Rv Rv0090 YP_001286037.1 Mapped to H37Rv Rv0091 YP_001286038.1 Mapped to H37Rv Rv0092 YP_001286039.1 Mapped to H37Rv Rv0093c YP_001286040.1 Mapped to H37Rv Rv0094c YP_001286041.1 Mapped to H37Rv Rv0095c YP_001286042.1 Mapped to H37Rv Rv0096 YP_001286043.1 Mapped to H37Rv Rv0097 YP_001286044.1 Mapped to H37Rv Rv0098 YP_001286045.1 activates fatty acids by binding to coenzyme A YP_001286046.1 Mapped to H37Rv Rv0100 YP_001286047.1 Mapped to H37Rv Rv0101 YP_001286048.1 Mapped to H37Rv Rv0102 YP_001286049.1 Mapped to H37Rv Rv0103c YP_001286050.1 Mapped to H37Rv Rv0104 YP_001286051.1 required for 70S ribosome assembly YP_001286052.1 Mapped to H37Rv Rv0106 YP_001286053.1 Mapped to H37Rv Rv0107c YP_001286054.1 Mapped to H37Rv Rv0108c YP_001286055.1 Mapped to H37Rv Rv0109 YP_001286056.1 Mapped to H37Rv Rv0110 YP_001286057.1 Mapped to H37Rv Rv0111 YP_001286058.1 Mapped to H37Rv Rv0112 YP_001286059.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001286060.1 Mapped to H37Rv Rv0114 YP_001286061.1 Mapped to H37Rv Rv0115 YP_001286062.1 Mapped to H37Rv Rv0116c YP_001286063.1 Mapped to H37Rv Rv0117 YP_001286064.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_001286065.1 activates fatty acids by binding to coenzyme A YP_001286066.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001286067.1 Mapped to H37Rv Rv0121c YP_001286068.1 Mapped to H37Rv Rv0122 YP_001286069.1 Mapped to H37Rv Rv0123 YP_001286070.1 Mapped to H37Rv Rv0124 YP_001286071.1 Mapped to H37Rv Rv0125 YP_001286072.1 Mapped to H37Rv Rv0126 YP_001286073.1 Mapped to H37Rv Rv0127 YP_001286074.1 Mapped to H37Rv Rv0128 YP_001286075.1 Mapped to H37Rv Rv0129c YP_001286076.1 Mapped to H37Rv Rv0130 YP_001286077.1 Mapped to H37Rv Rv0131c YP_001286078.1 Mapped to H37Rv Rv0132c YP_001286079.1 Mapped to H37Rv Rv0133 YP_001286080.1 Mapped to H37Rv Rv0134 YP_001286081.1 Mapped to H37Rv Rv0135c YP_001286082.1 Mapped to H37Rv Rv0136 YP_001286083.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001286084.1 Mapped to H37Rv Rv0138 YP_001286085.1 Mapped to H37Rv Rv0139 YP_001286086.1 Mapped to H37Rv Rv0140 YP_001286087.1 Mapped to H37Rv Rv0141c YP_001286088.1 Mapped to H37Rv Rv0142 YP_001286089.1 Mapped to H37Rv Rv0143c YP_001286090.1 Mapped to H37Rv Rv0144 YP_001286091.1 Mapped to H37Rv Rv0145 YP_001286092.1 Mapped to H37Rv Rv0146 YP_001286093.1 Mapped to H37Rv Rv0147 YP_001286094.1 Mapped to H37Rv Rv0148 YP_001286095.1 Mapped to H37Rv Rv0149 YP_001286096.1 Mapped to H37Rv Rv0150c YP_001286097.1 Mapped to H37Rv Rv0151c YP_001286098.1 Mapped to H37Rv Rv0152c YP_001286099.1 Mapped to H37Rv Rv0153c YP_001286100.1 Mapped to H37Rv Rv0154c YP_001286101.1 Mapped to H37Rv Rv0155 YP_001286102.1 Mapped to H37Rv Rv0156 YP_001286103.1 Mapped to H37Rv Rv0157 YP_001286104.1 Mapped to H37Rv Rv0158 YP_001286105.1 Mapped to H37Rv Rv0159c YP_001286106.1 Mapped to H37Rv Rv0160c YP_001286107.1 Mapped to H37Rv Rv0161 YP_001286108.1 Mapped to H37Rv Rv0162c YP_001286109.1 Mapped to H37Rv Rv0163 YP_001286110.1 Mapped to H37Rv Rv0164 YP_001286111.1 Mapped to H37Rv Rv0165c YP_001286112.1 activates fatty acids by binding to coenzyme A YP_001286113.1 Mapped to H37Rv Rv0167 YP_001286114.1 Mapped to H37Rv Rv0168 YP_001286115.1 Mapped to H37Rv Rv0169 YP_001286116.1 Mapped to H37Rv Rv0170 YP_001286117.1 Mapped to H37Rv Rv0171 YP_001286118.1 Mapped to H37Rv Rv0172 YP_001286119.1 Mapped to H37Rv Rv0173 YP_001286120.1 Mapped to H37Rv Rv0174 YP_001286121.1 Mapped to H37Rv Rv0175 YP_001286122.1 Mapped to H37Rv Rv0176 YP_001286123.1 Mapped to H37Rv Rv0177 YP_001286124.1 Mapped to H37Rv Rv0178 YP_001286125.1 Mapped to H37Rv Rv0179c YP_001286126.1 Mapped to H37Rv Rv0180c YP_001286127.1 Mapped to H37Rv Rv0181c YP_001286128.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001286129.1 Mapped to H37Rv Rv0183 YP_001286130.1 Mapped to H37Rv Rv0184 YP_001286131.1 Mapped to H37Rv Rv0185 YP_001286132.1 Mapped to H37Rv Rv0186 YP_001286133.1 Mapped to H37Rv Rv0187 YP_001286134.1 Mapped to H37Rv Rv0188 YP_001286135.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001286136.1 Mapped to H37Rv Rv0190 YP_001286137.1 Mapped to H37Rv Rv0191 YP_001286138.1 Mapped to H37Rv Rv0192A YP_001286139.1 Mapped to H37Rv Rv0192 YP_001286140.1 Mapped to H37Rv Rv0193c YP_001286141.1 Mapped to H37Rv Rv0194 YP_001286142.1 Mapped to H37Rv Rv0195 YP_001286143.1 Mapped to H37Rv Rv0196 YP_001286144.1 Mapped to H37Rv Rv0197 YP_001286145.1 Mapped to H37Rv Rv0198c YP_001286146.1 Mapped to H37Rv Rv0199 YP_001286147.1 Mapped to H37Rv Rv0200 YP_001286148.1 Mapped to H37Rv Rv0201c YP_001286149.1 Mapped to H37Rv Rv0202c YP_001286150.1 Mapped to H37Rv Rv0203 YP_001286151.1 Mapped to H37Rv Rv0204c YP_001286152.1 Mapped to H37Rv Rv0205 YP_001286153.1 Mapped to H37Rv Rv0206c YP_001286154.1 Mapped to H37Rv Rv0207c YP_001286155.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001286156.1 Mapped to H37Rv Rv0209 YP_001286157.1 Mapped to H37Rv Rv0210 YP_001286158.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001286159.1 Mapped to H37Rv Rv0212c YP_001286160.1 Mapped to H37Rv Rv0213c YP_001286161.1 activates fatty acids by binding to coenzyme A YP_001286162.1 Mapped to H37Rv Rv0215c YP_001286163.1 Mapped to H37Rv Rv0216 YP_001286164.1 Mapped to H37Rv Rv0217c YP_001286165.1 Mapped to H37Rv Rv0218 YP_001286166.1 Mapped to H37Rv Rv0219 YP_001286167.1 Mapped to H37Rv Rv0220 YP_001286168.1 Mapped to H37Rv Rv0221 YP_001286169.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286170.1 Mapped to H37Rv Rv0223c YP_001286171.1 Mapped to H37Rv Rv0224c YP_001286172.1 Mapped to H37Rv Rv0225 YP_001286173.1 Mapped to H37Rv Rv0226c YP_001286174.1 Mapped to H37Rv Rv0227c YP_001286175.1 Mapped to H37Rv Rv0228 YP_001286176.1 Mapped to H37Rv Rv0229c YP_001286177.1 Mapped to H37Rv Rv0230c YP_001286178.1 Mapped to H37Rv Rv0231 YP_001286179.1 Mapped to H37Rv Rv0232 YP_001286180.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001286181.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate YP_001286182.1 Mapped to H37Rv Rv0235c YP_001286183.1 Mapped to H37Rv Rv0236c YP_001286184.1 Mapped to H37Rv Rv0236A YP_001286185.1 Mapped to H37Rv Rv0237 YP_001286186.1 Mapped to H37Rv Rv0238 YP_001286187.1 Mapped to H37Rv Rv0239 YP_001286188.1 Mapped to H37Rv Rv0240 YP_001286189.1 Mapped to H37Rv Rv0241c YP_001286190.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001286191.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001286192.1 Mapped to H37Rv Rv0244c YP_001286193.1 Mapped to H37Rv Rv0245 YP_001286194.1 Mapped to H37Rv Rv0246 YP_001286195.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source YP_001286196.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001286197.1 Mapped to H37Rv Rv0249c YP_001286198.1 Mapped to H37Rv Rv0250c YP_001286199.1 Mapped to H37Rv Rv0251c YP_001286200.1 Mapped to H37Rv Rv0252 YP_001286201.1 Mapped to H37Rv Rv0253 YP_001286202.1 Mapped to H37Rv Rv0254c YP_001286203.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001286204.1 Mapped to H37Rv Rv0256c YP_001286205.1 Mapped to H37Rv Rv0257 YP_001286206.1 Mapped to H37Rv Rv0257 YP_001286207.1 Mapped to H37Rv Rv0258c YP_001286208.1 Mapped to H37Rv Rv0259c YP_001286209.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001286210.1 Mapped to H37Rv Rv0261c YP_001286211.1 Mapped to H37Rv Rv0262c YP_001286212.1 Mapped to H37Rv Rv0263c YP_001286213.1 Mapped to H37Rv Rv0264c YP_001286214.1 Mapped to H37Rv Rv0265c YP_001286215.1 Mapped to H37Rv Rv0266c YP_001286216.1 Mapped to H37Rv Rv0267 YP_001286217.1 Mapped to H37Rv Rv0268c YP_001286218.1 Mapped to H37Rv Rv0269c YP_001286219.1 activates fatty acids by binding to coenzyme A YP_001286220.1 Mapped to H37Rv Rv0271c YP_001286221.1 Mapped to H37Rv Rv0272c YP_001286222.1 Mapped to H37Rv Rv0273c YP_001286223.1 Mapped to H37Rv Rv0274 YP_001286224.1 Mapped to H37Rv Rv0275c YP_001286225.1 Mapped to H37Rv Rv0276 YP_001286226.1 Mapped to H37Rv Rv0277c YP_001286228.1 Mapped to H37Rv Rv0278c YP_001286229.1 Mapped to H37Rv Rv0278c YP_001286230.1 Mapped to H37Rv Rv0278c YP_001286231.1 Mapped to H37Rv Rv0279c YP_001286232.1 Mapped to H37Rv Rv0280 YP_001286233.1 Mapped to H37Rv Rv0281 YP_001286234.1 Mapped to H37Rv Rv0282 YP_001286235.1 Mapped to H37Rv Rv0283 YP_001286236.1 Mapped to H37Rv Rv0284 YP_001286237.1 Mapped to H37Rv Rv0285 YP_001286238.1 Mapped to H37Rv Rv0286 YP_001286239.1 Mapped to H37Rv Rv0287 YP_001286240.1 Mapped to H37Rv Rv0288 YP_001286241.1 Mapped to H37Rv Rv0289 YP_001286242.1 Mapped to H37Rv Rv0290 YP_001286243.1 Mapped to H37Rv Rv0291 YP_001286244.1 Mapped to H37Rv Rv0292 YP_001286245.1 Mapped to H37Rv Rv0293c YP_001286246.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001286247.1 Mapped to H37Rv Rv0295c YP_001286248.1 Mapped to H37Rv Rv0296c YP_001286249.1 Mapped to H37Rv Rv0297 YP_001286250.1 Mapped to H37Rv Rv0298 YP_001286251.1 Mapped to H37Rv Rv0299 YP_001286252.1 Mapped to H37Rv Rv0301 YP_001286253.1 Mapped to H37Rv Rv0302 YP_001286254.1 Mapped to H37Rv Rv0303 YP_001286255.1 Mapped to H37Rv Rv0303 YP_001286256.1 Mapped to H37Rv Rv0306 YP_001286257.1 Mapped to H37Rv Rv0307c YP_001286258.1 Mapped to H37Rv Rv0308 YP_001286259.1 Mapped to H37Rv Rv0309 YP_001286260.1 Mapped to H37Rv Rv0310c YP_001286261.1 Mapped to H37Rv Rv0311 YP_001286262.1 Mapped to H37Rv Rv0312 YP_001286263.1 Mapped to H37Rv Rv0313 YP_001286264.1 Mapped to H37Rv Rv0314c YP_001286265.1 Mapped to H37Rv Rv0315 YP_001286266.1 Mapped to H37Rv Rv0316 YP_001286267.1 Mapped to H37Rv Rv0317c YP_001286268.1 Mapped to H37Rv Rv0318c YP_001286269.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_001286270.1 Mapped to H37Rv Rv0320 YP_001286271.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001286272.1 Mapped to H37Rv Rv0322 YP_001286273.1 Mapped to H37Rv Rv0323c YP_001286274.1 Mapped to H37Rv Rv0324 YP_001286275.1 Mapped to H37Rv Rv0325 YP_001286276.1 Mapped to H37Rv Rv0326 YP_001286277.1 Mapped to H37Rv Rv0327c YP_001286278.1 Mapped to H37Rv Rv0328 YP_001286279.1 Mapped to H37Rv Rv0329c YP_001286280.1 Mapped to H37Rv Rv0330c YP_001286281.1 Mapped to H37Rv Rv0331 YP_001286282.1 Mapped to H37Rv Rv0332 YP_001286283.1 Mapped to H37Rv Rv0333 YP_001286284.1 Mapped to H37Rv Rv0334 YP_001286285.1 Mapped to H37Rv Rv0335c YP_001286286.1 Mapped to H37Rv Rv0336 YP_001286287.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001286288.1 Mapped to H37Rv Rv0338c YP_001286289.1 Mapped to H37Rv Rv0339c YP_001286290.1 Mapped to H37Rv Rv0340 YP_001286291.1 Mapped to H37Rv Rv0341 YP_001286292.1 Mapped to H37Rv Rv0342 YP_001286293.1 Mapped to H37Rv Rv0343 YP_001286294.1 Mapped to H37Rv Rv0344c YP_001286295.1 Mapped to H37Rv Rv0345 YP_001286296.1 Mapped to H37Rv Rv0346c YP_001286297.1 Mapped to H37Rv Rv0347 YP_001286298.1 Mapped to H37Rv Rv0348 YP_001286299.1 Mapped to H37Rv Rv0349 YP_001286300.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001286301.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001286302.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001286303.1 Mapped to H37Rv Rv0353 YP_001286304.1 Mapped to H37Rv Rv0354c YP_001286305.1 Mapped to H37Rv Rv0355c YP_001286306.1 Mapped to H37Rv Rv0356c YP_001286307.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001286308.1 Mapped to H37Rv Rv0358 YP_001286309.1 Mapped to H37Rv Rv0359 YP_001286310.1 Mapped to H37Rv Rv0360c YP_001286311.1 Mapped to H37Rv Rv0361 YP_001286312.1 Mapped to H37Rv Rv0362 YP_001286313.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001286314.1 Mapped to H37Rv Rv0364 YP_001286315.1 Mapped to H37Rv Rv0365c YP_001286316.1 Mapped to H37Rv Rv0366c YP_001286317.1 Mapped to H37Rv Rv0367c YP_001286318.1 Mapped to H37Rv Rv0368c YP_001286319.1 Mapped to H37Rv Rv0369c YP_001286320.1 Mapped to H37Rv Rv0370c YP_001286321.1 Mapped to H37Rv Rv0371c YP_001286322.1 Mapped to H37Rv Rv0372c YP_001286323.1 Mapped to H37Rv Rv0373c YP_001286324.1 Mapped to H37Rv Rv0374c YP_001286325.1 Mapped to H37Rv Rv0375c YP_001286326.1 Mapped to H37Rv Rv0376c YP_001286327.1 Mapped to H37Rv Rv0377 YP_001286328.1 Mapped to H37Rv Rv0378 YP_001286329.1 Mapped to H37Rv Rv0379 YP_001286330.1 Mapped to H37Rv Rv0380c YP_001286331.1 Mapped to H37Rv Rv0381c YP_001286332.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001286333.1 Mapped to H37Rv Rv0383c YP_001286334.1 Mapped to H37Rv Rv0384c YP_001286335.1 Mapped to H37Rv Rv0385 YP_001286336.1 Mapped to H37Rv Rv0386 YP_001286337.1 Mapped to H37Rv Rv0386 YP_001286338.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001286339.1 Mapped to H37Rv Rv0390 YP_001286340.1 Mapped to H37Rv Rv0391 YP_001286341.1 Mapped to H37Rv Rv0392c YP_001286342.1 Mapped to H37Rv Rv0393 YP_001286343.1 Mapped to H37Rv Rv0394c YP_001286344.1 Mapped to H37Rv Rv0395 YP_001286345.1 Mapped to H37Rv Rv0396 YP_001286346.1 Mapped to H37Rv Rv0397 YP_001286347.1 Mapped to H37Rv Rv0397 YP_001286348.1 Mapped to H37Rv Rv0398c YP_001286349.1 Mapped to H37Rv Rv0399c YP_001286350.1 Mapped to H37Rv Rv0400c YP_001286351.1 Mapped to H37Rv Rv0401 YP_001286352.1 Mapped to H37Rv Rv0402c YP_001286353.1 Mapped to H37Rv Rv0403c YP_001286354.1 activates fatty acids by binding to coenzyme A YP_001286355.1 Mapped to H37Rv Rv0405 YP_001286356.1 Mapped to H37Rv Rv0406c YP_001286357.1 Mapped to H37Rv Rv0407 YP_001286358.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001286359.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001286360.1 Mapped to H37Rv Rv0410c YP_001286361.1 Mapped to H37Rv Rv0411c YP_001286362.1 Mapped to H37Rv Rv0412c YP_001286363.1 Mapped to H37Rv Rv0413 YP_001286364.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001286365.1 Mapped to H37Rv Rv0415 YP_001286366.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001286367.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001286368.1 Mapped to H37Rv Rv0418 YP_001286369.1 Mapped to H37Rv Rv0419 YP_001286370.1 Mapped to H37Rv Rv0420c YP_001286371.1 Mapped to H37Rv Rv0421c YP_001286372.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001286373.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001286374.1 Mapped to H37Rv Rv0424c YP_001286375.1 Mapped to H37Rv Rv0425c YP_001286376.1 Mapped to H37Rv Rv0426c YP_001286377.1 Mapped to H37Rv Rv0427c YP_001286378.1 Mapped to H37Rv Rv0428c YP_001286379.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001286380.1 Mapped to H37Rv Rv0430 YP_001286381.1 Mapped to H37Rv Rv0431 YP_001286382.1 Mapped to H37Rv Rv0432 YP_001286383.1 ATP-dependent carboxylate-amine ligase YP_001286384.1 Mapped to H37Rv Rv0434 YP_001286385.1 Mapped to H37Rv Rv0435c YP_001286386.1 Mapped to H37Rv Rv0436c YP_001286387.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001286388.1 Mapped to H37Rv Rv0438c YP_001286389.1 Mapped to H37Rv Rv0439c YP_001286390.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001286391.1 Mapped to H37Rv Rv0441c YP_001286392.1 Mapped to H37Rv Rv0442c YP_001286393.1 Mapped to H37Rv Rv0443 YP_001286394.1 Mapped to H37Rv Rv0444c YP_001286395.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins YP_001286396.1 Mapped to H37Rv Rv0446c YP_001286397.1 Mapped to H37Rv Rv0446c YP_001286398.1 Mapped to H37Rv Rv0447c YP_001286399.1 Mapped to H37Rv Rv0448c YP_001286400.1 Mapped to H37Rv Rv0449c YP_001286401.1 Mapped to H37Rv Rv0450c YP_001286402.1 Mapped to H37Rv Rv0451c YP_001286403.1 Mapped to H37Rv Rv0452 YP_001286404.1 Mapped to H37Rv Rv0453 YP_001286405.1 Mapped to H37Rv Rv0453 YP_001286406.1 Mapped to H37Rv Rv0455c YP_001286407.1 catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286408.1 Mapped to H37Rv Rv0456A YP_001286409.1 Mapped to H37Rv Rv0457c YP_001286410.1 Mapped to H37Rv Rv0458 YP_001286411.1 Mapped to H37Rv Rv0459 YP_001286412.1 Mapped to H37Rv Rv0460 YP_001286413.1 Mapped to H37Rv Rv0461 YP_001286414.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component YP_001286415.1 Mapped to H37Rv Rv0463 YP_001286416.1 Mapped to H37Rv Rv0464c YP_001286417.1 Mapped to H37Rv Rv0465c YP_001286418.1 Mapped to H37Rv Rv0466 YP_001286419.1 Mapped to H37Rv Rv0467 YP_001286420.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001286421.1 Mapped to H37Rv Rv0469 YP_001286422.1 Mapped to H37Rv Rv0470c YP_001286423.1 Mapped to H37Rv Rv0470A YP_001286424.1 Mapped to H37Rv Rv0471c YP_001286425.1 Mapped to H37Rv Rv0472c YP_001286426.1 Mapped to H37Rv Rv0473 YP_001286427.1 Mapped to H37Rv Rv0474 YP_001286428.1 Mapped to H37Rv Rv0475 YP_001286429.1 Mapped to H37Rv Rv0476 YP_001286430.1 Mapped to H37Rv Rv0477 YP_001286431.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001286432.1 Mapped to H37Rv Rv0479c YP_001286433.1 Mapped to H37Rv Rv0480c YP_001286434.1 Mapped to H37Rv Rv0481c YP_001286435.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001286436.1 Mapped to H37Rv Rv0483 YP_001286437.1 Mapped to H37Rv Rv0484c YP_001286438.1 Mapped to H37Rv Rv0485 YP_001286439.1 Mapped to H37Rv Rv0486 YP_001286440.1 Mapped to H37Rv Rv0487 YP_001286441.1 Mapped to H37Rv Rv0488 YP_001286442.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001286443.1 Mapped to H37Rv Rv0490 YP_001286444.1 Mapped to H37Rv Rv0491 YP_001286445.1 Mapped to H37Rv Rv0492c YP_001286446.1 Mapped to H37Rv Rv0492A YP_001286447.1 Mapped to H37Rv Rv0493c YP_001286448.1 Mapped to H37Rv Rv0494 YP_001286449.1 Mapped to H37Rv Rv0495c YP_001286450.1 Mapped to H37Rv Rv0496 YP_001286451.1 Mapped to H37Rv Rv0497 YP_001286452.1 Mapped to H37Rv Rv0498 YP_001286453.1 Mapped to H37Rv Rv0499 YP_001286454.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001286455.1 Mapped to H37Rv Rv0500A YP_001286456.1 Mapped to H37Rv Rv0500B YP_001286457.1 Mapped to H37Rv Rv0501 YP_001286458.1 Mapped to H37Rv Rv0502 YP_001286459.1 Mapped to H37Rv Rv0503c YP_001286460.1 Mapped to H37Rv Rv0504c YP_001286461.1 Mapped to H37Rv Rv0505c YP_001286462.1 Mapped to H37Rv Rv0506 YP_001286463.1 Mapped to H37Rv Rv0507 YP_001286464.1 Mapped to H37Rv Rv0508 YP_001286465.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001286466.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001286467.1 Mapped to H37Rv Rv0511 YP_001286468.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001286469.1 Mapped to H37Rv Rv0513 YP_001286470.1 Mapped to H37Rv Rv0514 YP_001286471.1 Mapped to H37Rv Rv0515 YP_001286472.1 Mapped to H37Rv Rv0516c YP_001286473.1 Mapped to H37Rv Rv0517 YP_001286474.1 Mapped to H37Rv Rv0518 YP_001286475.1 Mapped to H37Rv Rv0519c YP_001286476.1 Mapped to H37Rv Rv0520 YP_001286477.1 Mapped to H37Rv Rv0521 YP_001286478.1 Mapped to H37Rv Rv0522 YP_001286479.1 Mapped to H37Rv Rv0523c YP_001286480.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001286481.1 Mapped to H37Rv Rv0525 YP_001286482.1 Mapped to H37Rv Rv0526 YP_001286483.1 Mapped to H37Rv Rv0527 YP_001286484.1 Mapped to H37Rv Rv0528 YP_001286485.1 Mapped to H37Rv Rv0529 YP_001286486.1 Mapped to H37Rv Rv0530 YP_001286487.1 Mapped to H37Rv Rv0531 YP_001286488.1 Mapped to H37Rv Rv0532 YP_001286489.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001286490.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001286491.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate YP_001286492.1 Mapped to H37Rv Rv0536 YP_001286493.1 Mapped to H37Rv Rv0537c YP_001286494.1 Mapped to H37Rv Rv0538 YP_001286495.1 Mapped to H37Rv Rv0539 YP_001286496.1 Mapped to H37Rv Rv0540 YP_001286497.1 Mapped to H37Rv Rv0541c YP_001286498.1 Mapped to H37Rv Rv0542c YP_001286499.1 Mapped to H37Rv Rv0543c YP_001286500.1 Mapped to H37Rv Rv0544c YP_001286501.1 Mapped to H37Rv Rv0545c YP_001286502.1 Mapped to H37Rv Rv0546c YP_001286503.1 Mapped to H37Rv Rv0547c YP_001286504.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001286505.1 Mapped to H37Rv Rv0549c YP_001286506.1 activates fatty acids by binding to coenzyme A YP_001286507.1 Mapped to H37Rv Rv0552 YP_001286508.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001286509.1 Mapped to H37Rv Rv0554 YP_001286510.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001286511.1 Mapped to H37Rv Rv0556 YP_001286512.1 Mapped to H37Rv Rv0557 YP_001286513.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001286514.1 Mapped to H37Rv Rv0559c YP_001286515.1 Mapped to H37Rv Rv0560c YP_001286516.1 Mapped to H37Rv Rv0561c YP_001286517.1 Mapped to H37Rv Rv0562 YP_001286518.1 putative metalloprotease YP_001286519.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001286520.1 Mapped to H37Rv Rv0565c YP_001286521.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001286522.1 Mapped to H37Rv Rv0567 YP_001286523.1 Mapped to H37Rv Rv0568 YP_001286524.1 Mapped to H37Rv Rv0569 YP_001286525.1 Mapped to H37Rv Rv0570 YP_001286526.1 Mapped to H37Rv Rv0571c YP_001286527.1 Mapped to H37Rv Rv0572c YP_001286528.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001286529.1 Mapped to H37Rv Rv0574c YP_001286530.1 Mapped to H37Rv Rv0575c YP_001286531.1 Mapped to H37Rv Rv0576 YP_001286532.1 Mapped to H37Rv Rv0577 YP_001286533.1 Mapped to H37Rv Rv0578c YP_001286534.1 Mapped to H37Rv Rv0577 YP_001286535.1 Mapped to H37Rv Rv0579 YP_001286536.1 Mapped to H37Rv Rv0580c YP_001286537.1 Mapped to H37Rv Rv0581 YP_001286538.1 Mapped to H37Rv Rv0582 YP_001286539.1 Mapped to H37Rv Rv0583c YP_001286540.1 Mapped to H37Rv Rv0584 YP_001286541.1 Mapped to H37Rv Rv0585c YP_001286542.1 Mapped to H37Rv Rv0586 YP_001286543.1 Mapped to H37Rv Rv0587 YP_001286544.1 Mapped to H37Rv Rv0588 YP_001286545.1 Mapped to H37Rv Rv0589 YP_001286546.1 Mapped to H37Rv Rv0590 YP_001286547.1 Mapped to H37Rv Rv0590A YP_001286548.1 Mapped to H37Rv Rv0591 YP_001286549.1 Mapped to H37Rv Rv0592 YP_001286550.1 Mapped to H37Rv Rv0593 YP_001286551.1 Mapped to H37Rv Rv0594 YP_001286552.1 Mapped to H37Rv Rv0595c YP_001286553.1 Mapped to H37Rv Rv0596c YP_001286554.1 Mapped to H37Rv Rv0597c YP_001286555.1 Mapped to H37Rv Rv0598c YP_001286556.1 Mapped to H37Rv Rv0599c YP_001286557.1 Mapped to H37Rv Rv0599c YP_001286558.1 Mapped to H37Rv Rv0602c YP_001286559.1 Mapped to H37Rv Rv0603 YP_001286560.1 Mapped to H37Rv Rv0604 YP_001286561.1 Mapped to H37Rv Rv0605 YP_001286562.1 Mapped to H37Rv Rv0606 YP_001286563.1 Mapped to H37Rv Rv0607 YP_001286564.1 Mapped to H37Rv Rv0608 YP_001286565.1 Mapped to H37Rv Rv0609 YP_001286566.1 Mapped to H37Rv Rv0610c YP_001286567.1 Mapped to H37Rv Rv0611c YP_001286568.1 Mapped to H37Rv Rv0612 YP_001286569.1 Mapped to H37Rv Rv0613c YP_001286570.1 Mapped to H37Rv Rv0614 YP_001286571.1 Mapped to H37Rv Rv0615 YP_001286572.1 Mapped to H37Rv Rv0616c YP_001286573.1 Mapped to H37Rv Rv0617 YP_001286574.1 Mapped to H37Rv Rv0618 YP_001286575.1 Mapped to H37Rv Rv0619 YP_001286576.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001286577.1 Mapped to H37Rv Rv0621 YP_001286578.1 Mapped to H37Rv Rv0622 YP_001286579.1 Mapped to H37Rv Rv0623 YP_001286580.1 Mapped to H37Rv Rv0624 YP_001286581.1 Mapped to H37Rv Rv0625c YP_001286582.1 Mapped to H37Rv Rv0626 YP_001286583.1 Mapped to H37Rv Rv0627 YP_001286584.1 Mapped to H37Rv Rv0628c YP_001286585.1 Mapped to H37Rv Rv0629c YP_001286586.1 Mapped to H37Rv Rv0630c YP_001286587.1 Mapped to H37Rv Rv0631c YP_001286588.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286589.1 Mapped to H37Rv Rv0633c YP_001286590.1 Mapped to H37Rv Rv0634c YP_001286591.1 Mapped to H37Rv Rv0634A YP_001286592.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001286593.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II YP_001286594.1 functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II YP_001286595.1 functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II YP_001286596.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001286597.1 Modulates Rho-dependent transcription termination YP_001286598.1 binds directly to 23S ribosomal RNA YP_001286599.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001286600.1 Mapped to H37Rv Rv0642c YP_001286601.1 Mapped to H37Rv Rv0643c YP_001286602.1 Mapped to H37Rv Rv0644c YP_001286603.1 Mapped to H37Rv Rv0645c YP_001286604.1 Mapped to H37Rv Rv0646c YP_001286605.1 Mapped to H37Rv Rv0647c YP_001286606.1 Mapped to H37Rv Rv0648 YP_001286607.1 Mapped to H37Rv Rv0649 YP_001286608.1 Mapped to H37Rv Rv0650 YP_001286609.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001286610.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001286611.1 Mapped to H37Rv Rv0653c YP_001286612.1 Mapped to H37Rv Rv0654 YP_001286613.1 Mapped to H37Rv Rv0655 YP_001286614.1 Mapped to H37Rv Rv0656c YP_001286615.1 Mapped to H37Rv Rv0657c YP_001286616.1 Mapped to H37Rv Rv0658c YP_001286617.1 Mapped to H37Rv Rv0659c YP_001286618.1 Mapped to H37Rv Rv0660c YP_001286619.1 Mapped to H37Rv Rv0661c YP_001286620.1 Mapped to H37Rv Rv0662c YP_001286621.1 Mapped to H37Rv Rv0663 YP_001286622.1 Mapped to H37Rv Rv0664 YP_001286623.1 Mapped to H37Rv Rv0665 YP_001286624.1 Mapped to H37Rv Rv0666 YP_001286626.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001286627.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001286628.1 Mapped to H37Rv Rv0669c YP_001286629.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001286630.1 Mapped to H37Rv Rv0671 YP_001286631.1 Mapped to H37Rv Rv0672 YP_001286632.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286633.1 Mapped to H37Rv Rv0674 YP_001286634.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286635.1 Mapped to H37Rv Rv0676c YP_001286636.1 Mapped to H37Rv Rv0677c YP_001286637.1 Mapped to H37Rv Rv0678 YP_001286638.1 Mapped to H37Rv Rv0679c YP_001286639.1 Mapped to H37Rv Rv0680c YP_001286640.1 Mapped to H37Rv Rv0681 YP_001286641.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001286642.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001286643.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001286644.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001286645.1 Mapped to H37Rv Rv0686 YP_001286646.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001286647.1 Mapped to H37Rv Rv0688 YP_001286648.1 Mapped to H37Rv Rv0689c YP_001286649.1 Mapped to H37Rv Rv0690c YP_001286650.1 Mapped to H37Rv Rv0691c YP_001286651.1 Mapped to H37Rv Rv0692 YP_001286652.1 Mapped to H37Rv Rv0693 YP_001286653.1 Mapped to H37Rv Rv0694 YP_001286654.1 Mapped to H37Rv Rv0695 YP_001286655.1 Mapped to H37Rv Rv0696 YP_001286656.1 Mapped to H37Rv Rv0697 YP_001286657.1 Mapped to H37Rv Rv0698 YP_001286658.1 Mapped to H37Rv Rv0698 YP_001286659.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001286660.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001286661.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001286662.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001286663.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001286664.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001286665.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001286666.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001286667.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001286668.1 one of the stabilizing components for the large ribosomal subunit YP_001286669.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001286670.1 Mapped to H37Rv Rv0711 YP_001286671.1 Mapped to H37Rv Rv0712 YP_001286672.1 Mapped to H37Rv Rv0713 YP_001286673.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001286674.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001286675.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001286676.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_001286677.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001286678.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001286679.1 binds 5S rRNA along with protein L5 and L25 YP_001286680.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001286681.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001286682.1 late assembly protein YP_001286683.1 Mapped to H37Rv Rv0724 YP_001286684.1 Mapped to H37Rv Rv0725c YP_001286685.1 Mapped to H37Rv Rv0726c YP_001286686.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001286687.1 Mapped to H37Rv Rv0728c YP_001286688.1 Mapped to H37Rv Rv0729 YP_001286689.1 Mapped to H37Rv Rv0730 YP_001286690.1 Mapped to H37Rv Rv0731c YP_001286691.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001286692.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001286693.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001286694.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins YP_001286695.1 Mapped to H37Rv Rv0736 YP_001286696.1 Mapped to H37Rv Rv0737 YP_001286697.1 Mapped to H37Rv Rv0738 YP_001286698.1 Mapped to H37Rv Rv0739 YP_001286699.1 Mapped to H37Rv Rv0740 YP_001286700.1 Mapped to H37Rv Rv0741 YP_001286701.1 Mapped to H37Rv Rv0742 YP_001286702.1 Mapped to H37Rv Rv0743c YP_001286703.1 Mapped to H37Rv Rv0744c YP_001286704.1 Mapped to H37Rv Rv0745 YP_001286705.1 Mapped to H37Rv Rv0746 YP_001286706.1 Mapped to H37Rv Rv0747 YP_001286707.1 Mapped to H37Rv Rv0748 YP_001286708.1 Mapped to H37Rv Rv0749 YP_001286709.1 Mapped to H37Rv Rv0750 YP_001286710.1 Mapped to H37Rv Rv0751c YP_001286711.1 Mapped to H37Rv Rv0752c YP_001286712.1 Mapped to H37Rv Rv0753c YP_001286713.1 Mapped to H37Rv Rv0754 YP_001286714.1 Mapped to H37Rv Rv0755c YP_001286715.1 Mapped to H37Rv Rv0755A YP_001286716.1 Mapped to H37Rv Rv0756c YP_001286717.1 Mapped to H37Rv Rv0757 YP_001286718.1 Mapped to H37Rv Rv0758 YP_001286719.1 Mapped to H37Rv Rv0759c YP_001286720.1 Mapped to H37Rv Rv0760c YP_001286721.1 Mapped to H37Rv Rv0761c YP_001286722.1 Mapped to H37Rv Rv0762c YP_001286723.1 Mapped to H37Rv Rv0763c YP_001286724.1 Mapped to H37Rv Rv0764c YP_001286725.1 Mapped to H37Rv Rv0765c YP_001286726.1 Mapped to H37Rv Rv0766c YP_001286727.1 Mapped to H37Rv Rv0767c YP_001286728.1 Mapped to H37Rv Rv0768 YP_001286729.1 Mapped to H37Rv Rv0769 YP_001286730.1 Mapped to H37Rv Rv0770 YP_001286731.1 Mapped to H37Rv Rv0771 YP_001286732.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001286733.1 Mapped to H37Rv Rv0773c YP_001286734.1 Mapped to H37Rv Rv0774c YP_001286735.1 Mapped to H37Rv Rv0775 YP_001286736.1 Mapped to H37Rv Rv0776c YP_001286737.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001286738.1 Mapped to H37Rv Rv0778 YP_001286739.1 Mapped to H37Rv Rv0779c YP_001286740.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001286741.1 Mapped to H37Rv Rv0781 YP_001286742.1 Mapped to H37Rv Rv0781 YP_001286743.1 Mapped to H37Rv Rv0783c YP_001286744.1 Mapped to H37Rv Rv0784 YP_001286745.1 proposed role in polysaccahride synthesis YP_001286746.1 Mapped to H37Rv Rv0786c YP_001286747.1 Mapped to H37Rv Rv0787 YP_001286748.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_001286749.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001286750.1 Mapped to H37Rv Rv0789c YP_001286751.1 Mapped to H37Rv Rv0790c YP_001286752.1 Mapped to H37Rv Rv0791c YP_001286753.1 Mapped to H37Rv Rv0792c YP_001286754.1 Mapped to H37Rv Rv0793 YP_001286755.1 Mapped to H37Rv Rv0794c YP_001286756.1 Mapped to H37Rv Rv0797 YP_001286757.1 Mapped to H37Rv Rv0797 YP_001286758.1 Mapped to H37Rv Rv0798c YP_001286759.1 Mapped to H37Rv Rv0799c YP_001286760.1 catalyzes the removal of amino acids from the N termini of peptides YP_001286761.1 Mapped to H37Rv Rv0801 YP_001286762.1 Mapped to H37Rv Rv0802c YP_001286763.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001286764.1 Mapped to H37Rv Rv0804 YP_001286765.1 Mapped to H37Rv Rv0805 YP_001286766.1 Mapped to H37Rv Rv0806c YP_001286767.1 Mapped to H37Rv Rv0807 YP_001286768.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001286769.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001286770.1 Mapped to H37Rv Rv0810c YP_001286771.1 Mapped to H37Rv Rv0811c YP_001286772.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001286773.1 Mapped to H37Rv Rv0813c YP_001286774.1 Mapped to H37Rv Rv0814c YP_001286775.1 Mapped to H37Rv Rv0815c YP_001286776.1 Mapped to H37Rv Rv0816c YP_001286777.1 Mapped to H37Rv Rv0817c YP_001286778.1 Mapped to H37Rv Rv0818 YP_001286779.1 Mapped to H37Rv Rv0819 YP_001286780.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001286781.1 Mapped to H37Rv Rv0821c YP_001286782.1 Mapped to H37Rv Rv0822c YP_001286783.1 Mapped to H37Rv Rv0823c YP_001286784.1 Mapped to H37Rv Rv0824c YP_001286785.1 Mapped to H37Rv Rv0825c YP_001286786.1 Mapped to H37Rv Rv0826 YP_001286787.1 Mapped to H37Rv Rv0827c YP_001286788.1 Mapped to H37Rv Rv0828c YP_001286789.1 Mapped to H37Rv Rv0829 YP_001286790.1 Mapped to H37Rv Rv0830 YP_001286791.1 Mapped to H37Rv Rv0831c YP_001286792.1 Mapped to H37Rv Rv0832 YP_001286793.1 Mapped to H37Rv Rv0833 YP_001286794.1 Mapped to H37Rv Rv0834c YP_001286795.1 Mapped to H37Rv Rv0835 YP_001286796.1 Mapped to H37Rv Rv0835 YP_001286797.1 Mapped to H37Rv Rv0835 YP_001286799.1 Mapped to H37Rv Rv0836c YP_001286800.1 Mapped to H37Rv Rv0837c YP_001286801.1 Mapped to H37Rv Rv0838 YP_001286802.1 Mapped to H37Rv Rv0839 YP_001286803.1 Mapped to H37Rv Rv0840c YP_001286804.1 Mapped to H37Rv Rv0842 YP_001286805.1 Mapped to H37Rv Rv0843 YP_001286806.1 Mapped to H37Rv Rv0844c YP_001286807.1 Mapped to H37Rv Rv0845 YP_001286808.1 Mapped to H37Rv Rv0846c YP_001286809.1 Mapped to H37Rv Rv0847 YP_001286810.1 Mapped to H37Rv Rv0848 YP_001286811.1 Mapped to H37Rv Rv0849 YP_001286812.1 Mapped to H37Rv Rv0850 YP_001286813.1 Mapped to H37Rv Rv0851c YP_001286814.1 Mapped to H37Rv Rv0852 YP_001286815.1 Mapped to H37Rv Rv0853c YP_001286816.1 Mapped to H37Rv Rv0854 YP_001286817.1 Mapped to H37Rv Rv0855 YP_001286818.1 Mapped to H37Rv Rv0856 YP_001286819.1 Mapped to H37Rv Rv0857 YP_001286820.1 Mapped to H37Rv Rv0858c YP_001286821.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001286822.1 Mapped to H37Rv Rv0860 YP_001286823.1 Mapped to H37Rv Rv0861c YP_001286824.1 Mapped to H37Rv Rv0862c YP_001286825.1 Mapped to H37Rv Rv0863 YP_001286826.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001286827.1 Mapped to H37Rv Rv0865 YP_001286828.1 Mapped to H37Rv Rv0866 YP_001286829.1 Mapped to H37Rv Rv0867c YP_001286830.1 Mapped to H37Rv Rv0868c YP_001286831.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001286832.1 Mapped to H37Rv Rv0870c YP_001286833.1 Mapped to H37Rv Rv0871 YP_001286834.1 Mapped to H37Rv Rv0872c YP_001286835.1 Mapped to H37Rv Rv0873 YP_001286836.1 Mapped to H37Rv Rv0874c YP_001286837.1 Mapped to H37Rv Rv0875c YP_001286838.1 Mapped to H37Rv Rv0876c YP_001286839.1 Mapped to H37Rv Rv0877 YP_001286840.1 Mapped to H37Rv Rv0878c YP_001286841.1 Mapped to H37Rv Rv0879c YP_001286842.1 Mapped to H37Rv Rv0880 YP_001286843.1 Mapped to H37Rv Rv0881 YP_001286844.1 Mapped to H37Rv Rv0882 YP_001286845.1 Mapped to H37Rv Rv0883c YP_001286846.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001286847.1 Mapped to H37Rv Rv0885 YP_001286848.1 Mapped to H37Rv Rv0886 YP_001286849.1 Mapped to H37Rv Rv0887c YP_001286852.1 Mapped to H37Rv Rv0888 YP_001286853.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle YP_001286854.1 Mapped to H37Rv Rv0890c YP_001286855.1 Mapped to H37Rv Rv0891c YP_001286856.1 Mapped to H37Rv Rv0892 YP_001286857.1 Mapped to H37Rv Rv0893c YP_001286858.1 Mapped to H37Rv Rv0894 YP_001286859.1 Mapped to H37Rv Rv0895 YP_001286860.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001286861.1 Mapped to H37Rv Rv0897c YP_001286862.1 Mapped to H37Rv Rv0898c YP_001286863.1 Mapped to H37Rv Rv0899 YP_001286864.1 Mapped to H37Rv Rv0901 YP_001286865.1 Mapped to H37Rv Rv0902c YP_001286866.1 Mapped to H37Rv Rv0903c YP_001286867.1 Mapped to H37Rv Rv0904c YP_001286868.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286869.1 Mapped to H37Rv Rv0906 YP_001286870.1 Mapped to H37Rv Rv0907 YP_001286871.1 Mapped to H37Rv Rv0908 YP_001286872.1 Mapped to H37Rv Rv0909 YP_001286873.1 Mapped to H37Rv Rv0910 YP_001286874.1 Mapped to H37Rv Rv0911 YP_001286875.1 Mapped to H37Rv Rv0912 YP_001286876.1 Mapped to H37Rv Rv0913c YP_001286877.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001286878.1 Mapped to H37Rv Rv0915c YP_001286879.1 Mapped to H37Rv Rv0916c YP_001286880.1 Mapped to H37Rv Rv0917 YP_001286881.1 Mapped to H37Rv Rv0918 YP_001286882.1 Mapped to H37Rv Rv0919 YP_001286883.1 Mapped to H37Rv Rv0920c YP_001286884.1 Mapped to H37Rv Rv0921 YP_001286885.1 Mapped to H37Rv Rv0922 YP_001286886.1 Mapped to H37Rv Rv0923c YP_001286887.1 Mapped to H37Rv Rv0924c YP_001286888.1 Mapped to H37Rv Rv0925c YP_001286889.1 Mapped to H37Rv Rv0926c YP_001286890.1 Mapped to H37Rv Rv0927c YP_001286891.1 Mapped to H37Rv Rv0928 YP_001286892.1 Mapped to H37Rv Rv0929 YP_001286893.1 Mapped to H37Rv Rv0930 YP_001286894.1 Mapped to H37Rv Rv0931c YP_001286895.1 Mapped to H37Rv Rv0932c YP_001286896.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001286897.1 Mapped to H37Rv Rv0934 YP_001286898.1 Mapped to H37Rv Rv0935 YP_001286899.1 Mapped to H37Rv Rv0936 YP_001286900.1 Mapped to H37Rv Rv0937c YP_001286901.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity YP_001286902.1 Mapped to H37Rv Rv0939 YP_001286903.1 Mapped to H37Rv Rv0940c YP_001286904.1 Mapped to H37Rv Rv0941c YP_001286905.1 Mapped to H37Rv Rv0943c YP_001286906.1 Mapped to H37Rv Rv0944 YP_001286907.1 Mapped to H37Rv Rv0945 YP_001286908.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001286910.1 Mapped to H37Rv Rv0947c YP_001286911.1 Mapped to H37Rv Rv0948c YP_001286912.1 Mapped to H37Rv Rv0949 YP_001286913.1 Mapped to H37Rv Rv0950c YP_001286914.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001286915.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001286916.1 Mapped to H37Rv Rv0953c YP_001286917.1 Mapped to H37Rv Rv0954 YP_001286918.1 Mapped to H37Rv Rv0955 YP_001286919.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001286920.1 involved in de novo purine biosynthesis YP_001286921.1 Mapped to H37Rv Rv0958 YP_001286922.1 Mapped to H37Rv Rv0959 YP_001286923.1 Mapped to H37Rv Rv0960 YP_001286924.1 Mapped to H37Rv Rv0961 YP_001286925.1 Mapped to H37Rv Rv0962c YP_001286926.1 Mapped to H37Rv Rv0963c YP_001286927.1 Mapped to H37Rv Rv0964c YP_001286928.1 Mapped to H37Rv Rv0965c YP_001286929.1 Mapped to H37Rv Rv0966c YP_001286930.1 Mapped to H37Rv Rv0967 YP_001286931.1 Mapped to H37Rv Rv0968 YP_001286932.1 Mapped to H37Rv Rv0969 YP_001286933.1 Mapped to H37Rv Rv0970 YP_001286934.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001286935.1 Mapped to H37Rv Rv0972c YP_001286936.1 Mapped to H37Rv Rv0973c YP_001286937.1 Mapped to H37Rv Rv0974c YP_001286938.1 Mapped to H37Rv Rv0975c YP_001286939.1 Mapped to H37Rv Rv0976c YP_001286940.1 Mapped to H37Rv Rv0977 YP_001286941.1 Mapped to H37Rv Rv0978c YP_001286942.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001286943.1 Mapped to H37Rv Rv0980c YP_001286944.1 Mapped to H37Rv Rv0981 YP_001286945.1 Mapped to H37Rv Rv0982 YP_001286946.1 Mapped to H37Rv Rv0983 YP_001286947.1 Mapped to H37Rv Rv0984 YP_001286948.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001286949.1 Mapped to H37Rv Rv0986 YP_001286950.1 Mapped to H37Rv Rv0987 YP_001286951.1 Mapped to H37Rv Rv0988 YP_001286952.1 Mapped to H37Rv Rv0989c YP_001286953.1 Mapped to H37Rv Rv0990c YP_001286954.1 Mapped to H37Rv Rv0991c YP_001286955.1 Mapped to H37Rv Rv0992c YP_001286956.1 Mapped to H37Rv Rv0993 YP_001286957.1 Mapped to H37Rv Rv0994 YP_001286958.1 Mapped to H37Rv Rv0995 YP_001286959.1 Mapped to H37Rv Rv0996 YP_001286961.1 Mapped to H37Rv Rv0997 YP_001286962.1 Mapped to H37Rv Rv0998 YP_001286963.1 Mapped to H37Rv Rv0999 YP_001286964.1 Mapped to H37Rv Rv1000c YP_001286965.1 catalyzes the degradation of arginine to citruline and ammonia YP_001286966.1 Mapped to H37Rv Rv1002c YP_001286967.1 Mapped to H37Rv Rv1003 YP_001286968.1 Mapped to H37Rv Rv1004c YP_001286969.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_001286970.1 Mapped to H37Rv Rv1006 YP_001286971.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001286972.1 Mapped to H37Rv Rv1008 YP_001286973.1 Mapped to H37Rv Rv1009 YP_001286974.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001286975.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_001286976.1 activates fatty acids by binding to coenzyme A YP_001286977.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001286978.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001286979.1 Mapped to H37Rv Rv1016c YP_001286980.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001286981.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001286982.1 Mapped to H37Rv Rv1019 YP_001286983.1 Mapped to H37Rv Rv1020 YP_001286984.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001286985.1 Mapped to H37Rv Rv1022 YP_001286986.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001286987.1 Mapped to H37Rv Rv1024 YP_001286988.1 Mapped to H37Rv Rv1025 YP_001286989.1 Mapped to H37Rv Rv1026 YP_001286990.1 Mapped to H37Rv Rv1027c YP_001286991.1 Mapped to H37Rv Rv1028c YP_001286992.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001286993.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001286994.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_001286995.1 Mapped to H37Rv Rv1032c YP_001286996.1 Mapped to H37Rv Rv1033c YP_001286997.1 Mapped to H37Rv Rv1034c YP_001286998.1 Mapped to H37Rv Rv1035c YP_001286999.1 Mapped to H37Rv Rv1036c YP_001287000.1 Mapped to H37Rv Rv1037c YP_001287001.1 Mapped to H37Rv Rv1038c YP_001287002.1 Mapped to H37Rv Rv1039c YP_001287003.1 Mapped to H37Rv Rv1040c YP_001287004.1 Mapped to H37Rv Rv1041c YP_001287005.1 Mapped to H37Rv Rv1042c YP_001287006.1 Mapped to H37Rv Rv1043c YP_001287007.1 Mapped to H37Rv Rv1044 YP_001287008.1 Mapped to H37Rv Rv1045 YP_001287009.1 Mapped to H37Rv Rv1046c YP_001287010.1 Mapped to H37Rv Rv1047 YP_001287011.1 Mapped to H37Rv Rv1048c YP_001287012.1 Mapped to H37Rv Rv1049 YP_001287013.1 Mapped to H37Rv Rv1050 YP_001287014.1 Mapped to H37Rv Rv1051c YP_001287016.1 Mapped to H37Rv Rv1052 YP_001287017.1 Mapped to H37Rv Rv1053c YP_001287018.1 Mapped to H37Rv Rv1054 YP_001287019.1 Mapped to H37Rv Rv1056 YP_001287020.1 Mapped to H37Rv Rv1057 YP_001287021.1 activates fatty acids by binding to coenzyme A YP_001287022.1 Mapped to H37Rv Rv1059 YP_001287023.1 Mapped to H37Rv Rv1060 YP_001287024.1 Mapped to H37Rv Rv1061 YP_001287025.1 Mapped to H37Rv Rv1062 YP_001287026.1 Mapped to H37Rv Rv1063c YP_001287027.1 Mapped to H37Rv Rv1064c YP_001287028.1 Mapped to H37Rv Rv1065 YP_001287029.1 Mapped to H37Rv Rv1066 YP_001287030.1 Mapped to H37Rv Rv1067c YP_001287031.1 Mapped to H37Rv Rv1068c YP_001287032.1 Mapped to H37Rv Rv1069c YP_001287033.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001287034.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001287035.1 Mapped to H37Rv Rv1072 YP_001287036.1 Mapped to H37Rv Rv1073 YP_001287037.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001287038.1 Mapped to H37Rv Rv1075c YP_001287039.1 Mapped to H37Rv Rv1076 YP_001287040.1 Mapped to H37Rv Rv1077 YP_001287041.1 Mapped to H37Rv Rv1078 YP_001287042.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001287043.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001287044.1 Mapped to H37Rv Rv1081c YP_001287045.1 Mapped to H37Rv Rv1082 YP_001287046.1 Mapped to H37Rv Rv1083 YP_001287047.1 Mapped to H37Rv Rv1084 YP_001287048.1 Mapped to H37Rv Rv1085c YP_001287049.1 Mapped to H37Rv Rv1086 YP_001287050.1 Mapped to H37Rv Rv1087 YP_001287051.1 Mapped to H37Rv Rv1087A YP_001287052.1 Mapped to H37Rv Rv1088 YP_001287053.1 Mapped to H37Rv Rv1089 YP_001287054.1 Mapped to H37Rv Rv1089 YP_001287055.1 Mapped to H37Rv Rv1089A YP_001287056.1 Mapped to H37Rv Rv1090 YP_001287057.1 Mapped to H37Rv Rv1091 YP_001287058.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001287059.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001287060.1 Mapped to H37Rv Rv1094 YP_001287061.1 Mapped to H37Rv Rv1095 YP_001287062.1 Mapped to H37Rv Rv1096 YP_001287063.1 Mapped to H37Rv Rv1097c YP_001287064.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001287065.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001287066.1 Mapped to H37Rv Rv1100 YP_001287067.1 Mapped to H37Rv Rv1101c YP_001287068.1 Mapped to H37Rv Rv1102c YP_001287069.1 Mapped to H37Rv Rv1103c YP_001287070.1 Mapped to H37Rv Rv1104 YP_001287071.1 Mapped to H37Rv Rv1104 YP_001287072.1 Mapped to H37Rv Rv1105 YP_001287073.1 Mapped to H37Rv Rv1106c YP_001287074.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001287075.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001287076.1 Mapped to H37Rv Rv1109c YP_001287077.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001287078.1 Mapped to H37Rv Rv1111c YP_001287079.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001287080.1 Mapped to H37Rv Rv1113 YP_001287081.1 Mapped to H37Rv Rv1114 YP_001287082.1 Mapped to H37Rv Rv1115 YP_001287083.1 Mapped to H37Rv Rv1116 YP_001287084.1 Mapped to H37Rv Rv1116A YP_001287085.1 Mapped to H37Rv Rv1117 YP_001287086.1 Mapped to H37Rv Rv1118c YP_001287087.1 Mapped to H37Rv Rv1119c YP_001287088.1 Mapped to H37Rv Rv1120c YP_001287089.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001287090.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001287091.1 Mapped to H37Rv Rv1123c YP_001287092.1 Mapped to H37Rv Rv1124 YP_001287093.1 Mapped to H37Rv Rv1125 YP_001287094.1 Mapped to H37Rv Rv1126c YP_001287095.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001287096.1 Mapped to H37Rv Rv1128c YP_001287097.1 Mapped to H37Rv Rv1129c YP_001287098.1 Mapped to H37Rv Rv1130 YP_001287099.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_001287100.1 Mapped to H37Rv Rv1132 YP_001287101.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001287102.1 Mapped to H37Rv Rv1135c YP_001287103.1 Mapped to H37Rv Rv1135A YP_001287104.1 Mapped to H37Rv Rv1136 YP_001287106.1 Mapped to H37Rv Rv1138c YP_001287107.1 Mapped to H37Rv Rv1139c YP_001287108.1 Mapped to H37Rv Rv1140 YP_001287109.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001287110.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001287111.1 Mapped to H37Rv Rv1143 YP_001287112.1 Mapped to H37Rv Rv1144 YP_001287113.1 Mapped to H37Rv Rv1144 YP_001287114.1 Mapped to H37Rv Rv1145 YP_001287115.1 Mapped to H37Rv Rv1146 YP_001287116.1 Mapped to H37Rv Rv1147 YP_001287117.1 Mapped to H37Rv Rv1147 YP_001287118.1 Mapped to H37Rv Rv1148c YP_001287119.1 Mapped to H37Rv Rv1148c YP_001287120.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001287121.1 Mapped to H37Rv Rv1152 YP_001287122.1 Mapped to H37Rv Rv1153c YP_001287123.1 Mapped to H37Rv Rv1154c YP_001287124.1 Mapped to H37Rv Rv1155 YP_001287125.1 Mapped to H37Rv Rv1156 YP_001287126.1 Mapped to H37Rv Rv1157c YP_001287127.1 Mapped to H37Rv Rv1158c YP_001287128.1 involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis YP_001287129.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001287130.1 Mapped to H37Rv Rv1160 YP_001287131.1 Mapped to H37Rv Rv1161 YP_001287132.1 Mapped to H37Rv Rv1162 YP_001287133.1 Mapped to H37Rv Rv1163 YP_001287134.1 Mapped to H37Rv Rv1164 YP_001287135.1 Mapped to H37Rv Rv1165 YP_001287136.1 Mapped to H37Rv Rv1166 YP_001287137.1 Mapped to H37Rv Rv1167c YP_001287138.1 Mapped to H37Rv Rv1168c YP_001287139.1 Mapped to H37Rv Rv1169c YP_001287140.1 Mapped to H37Rv Rv1170 YP_001287141.1 Mapped to H37Rv Rv1171 YP_001287142.1 Mapped to H37Rv Rv1172c YP_001287143.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis YP_001287144.1 Mapped to H37Rv Rv1174c YP_001287145.1 Mapped to H37Rv Rv1175c YP_001287146.1 Mapped to H37Rv Rv1176c YP_001287147.1 Mapped to H37Rv Rv1177 YP_001287148.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis YP_001287149.1 Mapped to H37Rv Rv1179c YP_001287150.1 Mapped to H37Rv Rv1180 YP_001287151.1 Mapped to H37Rv Rv1182 YP_001287152.1 Mapped to H37Rv Rv1183 YP_001287153.1 Mapped to H37Rv Rv1184c YP_001287154.1 activates fatty acids by binding to coenzyme A YP_001287155.1 Mapped to H37Rv Rv1186c YP_001287156.1 Mapped to H37Rv Rv1187 YP_001287157.1 Mapped to H37Rv Rv1188 YP_001287158.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001287159.1 Mapped to H37Rv Rv1190 YP_001287160.1 Mapped to H37Rv Rv1191 YP_001287161.1 Mapped to H37Rv Rv1192 YP_001287162.1 activates fatty acids by binding to coenzyme A YP_001287163.1 Mapped to H37Rv Rv1194c YP_001287164.1 Mapped to H37Rv Rv1195 YP_001287165.1 Mapped to H37Rv Rv1196 YP_001287166.1 Mapped to H37Rv Rv1197 YP_001287167.1 Mapped to H37Rv Rv1198 YP_001287168.1 Mapped to H37Rv Rv1199c YP_001287169.1 Mapped to H37Rv Rv1200 YP_001287170.1 Mapped to H37Rv Rv1201c YP_001287171.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate YP_001287172.1 Mapped to H37Rv Rv1203c YP_001287173.1 Mapped to H37Rv Rv1204c YP_001287174.1 Mapped to H37Rv Rv1205 YP_001287175.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_001287176.1 Mapped to H37Rv Rv1207 YP_001287177.1 Mapped to H37Rv Rv1208 YP_001287178.1 Mapped to H37Rv Rv1209 YP_001287179.1 Mapped to H37Rv Rv1210 YP_001287180.1 Mapped to H37Rv Rv1211 YP_001287181.1 Mapped to H37Rv Rv1212c YP_001287182.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001287183.1 Mapped to H37Rv Rv1214c YP_001287184.1 Mapped to H37Rv Rv1215c YP_001287185.1 Mapped to H37Rv Rv1216c YP_001287186.1 Mapped to H37Rv Rv1217c YP_001287187.1 Mapped to H37Rv Rv1218c YP_001287188.1 Mapped to H37Rv Rv1219c YP_001287189.1 Mapped to H37Rv Rv1220c YP_001287190.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence YP_001287191.1 Mapped to H37Rv Rv1222 YP_001287192.1 Mapped to H37Rv Rv1223 YP_001287193.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001287194.1 Mapped to H37Rv Rv1225c YP_001287195.1 Mapped to H37Rv Rv1226c YP_001287196.1 Mapped to H37Rv Rv1227c YP_001287197.1 Mapped to H37Rv Rv1228 YP_001287199.1 Mapped to H37Rv Rv1229c YP_001287200.1 Mapped to H37Rv Rv1230c YP_001287201.1 Mapped to H37Rv Rv1231c YP_001287202.1 Mapped to H37Rv Rv1232c YP_001287203.1 Mapped to H37Rv Rv1233c YP_001287204.1 Mapped to H37Rv Rv1234 YP_001287205.1 Mapped to H37Rv Rv1235 YP_001287206.1 Mapped to H37Rv Rv1236 YP_001287207.1 Mapped to H37Rv Rv1237 YP_001287208.1 Mapped to H37Rv Rv1238 YP_001287209.1 Mapped to H37Rv Rv1239c YP_001287210.1 catalyzes the oxidation of malate to oxaloacetate YP_001287211.1 Mapped to H37Rv Rv1241 YP_001287212.1 Mapped to H37Rv Rv1242 YP_001287213.1 Mapped to H37Rv Rv1243c YP_001287214.1 Mapped to H37Rv Rv1243c YP_001287215.1 Mapped to H37Rv Rv1244 YP_001287216.1 Mapped to H37Rv Rv1245c YP_001287217.1 Mapped to H37Rv Rv1246c YP_001287218.1 Mapped to H37Rv Rv1247c YP_001287219.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth YP_001287220.1 Mapped to H37Rv Rv1249c YP_001287221.1 Mapped to H37Rv Rv1250 YP_001287222.1 Mapped to H37Rv Rv1251c YP_001287223.1 Mapped to H37Rv Rv1252c YP_001287224.1 Mapped to H37Rv Rv1253 YP_001287225.1 Mapped to H37Rv Rv1254 YP_001287226.1 Mapped to H37Rv Rv1255c YP_001287227.1 Mapped to H37Rv Rv1256c YP_001287228.1 Mapped to H37Rv Rv1257c YP_001287229.1 Mapped to H37Rv Rv1258c YP_001287230.1 Mapped to H37Rv Rv1259 YP_001287231.1 Mapped to H37Rv Rv1260 YP_001287232.1 Mapped to H37Rv Rv1261c YP_001287233.1 Mapped to H37Rv Rv1262c YP_001287234.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001287235.1 Mapped to H37Rv Rv1264 YP_001287236.1 Mapped to H37Rv Rv1265 YP_001287237.1 Mapped to H37Rv Rv1266c YP_001287238.1 Mapped to H37Rv Rv1267c YP_001287239.1 Mapped to H37Rv Rv1268c YP_001287240.1 Mapped to H37Rv Rv1269c YP_001287241.1 Mapped to H37Rv Rv1270c YP_001287242.1 Mapped to H37Rv Rv1271c YP_001287243.1 Mapped to H37Rv Rv1272c YP_001287244.1 Mapped to H37Rv Rv1273c YP_001287245.1 Mapped to H37Rv Rv1274 YP_001287246.1 Mapped to H37Rv Rv1275 YP_001287247.1 Mapped to H37Rv Rv1276c YP_001287248.1 Mapped to H37Rv Rv1277 YP_001287249.1 Mapped to H37Rv Rv1278 YP_001287250.1 Mapped to H37Rv Rv1279 YP_001287251.1 Mapped to H37Rv Rv1280c YP_001287252.1 Mapped to H37Rv Rv1281c YP_001287253.1 Mapped to H37Rv Rv1282c YP_001287254.1 Mapped to H37Rv Rv1283c YP_001287255.1 Mapped to H37Rv Rv1284 YP_001287256.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001287257.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_001287258.1 Mapped to H37Rv Rv1287 YP_001287259.1 Mapped to H37Rv Rv1288 YP_001287260.1 Mapped to H37Rv Rv1289 YP_001287261.1 Mapped to H37Rv Rv1290c YP_001287262.1 Mapped to H37Rv Rv1290A YP_001287263.1 Mapped to H37Rv Rv1291c YP_001287264.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001287265.1 Mapped to H37Rv Rv1293 YP_001287266.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001287267.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001287268.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001287269.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001287270.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001287271.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001287272.1 Mapped to H37Rv Rv1300 YP_001287273.1 Mapped to H37Rv Rv1301 YP_001287274.1 Mapped to H37Rv Rv1302 YP_001287275.1 Mapped to H37Rv Rv1303 YP_001287276.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001287277.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001287278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001287279.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001287280.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001287281.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001287282.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001287283.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001287284.1 Mapped to H37Rv Rv1312 YP_001287285.1 Mapped to H37Rv Rv1313c YP_001287286.1 Mapped to H37Rv Rv1314c YP_001287287.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001287288.1 Mapped to H37Rv Rv1316c YP_001287289.1 Mapped to H37Rv Rv1317c YP_001287290.1 Mapped to H37Rv Rv1318c YP_001287291.1 Mapped to H37Rv Rv1319c YP_001287294.1 Mapped to H37Rv Rv1319c YP_001287295.1 Mapped to H37Rv Rv1319c YP_001287296.1 Mapped to H37Rv Rv1320c YP_001287297.1 Mapped to H37Rv Rv1321 YP_001287298.1 Mapped to H37Rv Rv1322 YP_001287299.1 Mapped to H37Rv Rv1322A YP_001287300.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001287301.1 Mapped to H37Rv Rv1324 YP_001287302.1 Mapped to H37Rv Rv1325c YP_001287303.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001287304.1 Mapped to H37Rv Rv1327c YP_001287305.1 Mapped to H37Rv Rv1328 YP_001287306.1 Mapped to H37Rv Rv1329c YP_001287307.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001287308.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001287309.1 Mapped to H37Rv Rv1332 YP_001287310.1 Mapped to H37Rv Rv1333 YP_001287311.1 Mapped to H37Rv Rv1336 YP_001287312.1 Mapped to H37Rv Rv1337 YP_001287313.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001287314.1 Mapped to H37Rv Rv1339 YP_001287315.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001287316.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001287317.1 Mapped to H37Rv Rv1342c YP_001287318.1 Mapped to H37Rv Rv1343c YP_001287319.1 carries the fatty acid chain in fatty acid biosynthesis YP_001287320.1 converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis YP_001287321.1 Mapped to H37Rv Rv1346 YP_001287322.1 Mapped to H37Rv Rv1347c YP_001287323.1 Mapped to H37Rv Rv1348 YP_001287324.1 Mapped to H37Rv Rv1349 YP_001287325.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001287326.1 Mapped to H37Rv Rv1351 YP_001287327.1 Mapped to H37Rv Rv1352 YP_001287328.1 Mapped to H37Rv Rv1353c YP_001287329.1 Mapped to H37Rv Rv1354c YP_001287330.1 Mapped to H37Rv Rv1355c YP_001287331.1 Mapped to H37Rv Rv1356c YP_001287332.1 Mapped to H37Rv Rv1357c YP_001287333.1 Mapped to H37Rv Rv1358 YP_001287334.1 Mapped to H37Rv Rv1358 YP_001287335.1 Mapped to H37Rv Rv1359 YP_001287336.1 Mapped to H37Rv Rv1360 YP_001287337.1 Mapped to H37Rv Rv1361c YP_001287338.1 Mapped to H37Rv Rv1362c YP_001287339.1 Mapped to H37Rv Rv1363c YP_001287340.1 Mapped to H37Rv Rv1364c YP_001287341.1 Mapped to H37Rv Rv1365c YP_001287342.1 Mapped to H37Rv Rv1366 YP_001287343.1 Mapped to H37Rv Rv1367c YP_001287344.1 Mapped to H37Rv Rv1368 YP_001287345.1 Mapped to H37Rv Rv1371 YP_001287346.1 Mapped to H37Rv Rv1372 YP_001287347.1 Mapped to H37Rv Rv1373 YP_001287348.1 Mapped to H37Rv Rv1374c YP_001287349.1 Mapped to H37Rv Rv1375 YP_001287350.1 Mapped to H37Rv Rv1376 YP_001287351.1 Mapped to H37Rv Rv1377c YP_001287352.1 Mapped to H37Rv Rv1378c YP_001287353.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001287354.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001287355.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001287356.1 Mapped to H37Rv Rv1382 YP_001287357.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001287358.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001287359.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001287360.1 Mapped to H37Rv Rv1386 YP_001287361.1 Mapped to H37Rv Rv1387 YP_001287362.1 Mapped to H37Rv Rv1388 YP_001287363.1 Essential for recycling GMP and indirectly, cGMP YP_001287364.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001287365.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001287366.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001287367.1 Mapped to H37Rv Rv1393c YP_001287368.1 Mapped to H37Rv Rv1394c YP_001287369.1 Mapped to H37Rv Rv1395 YP_001287370.1 Mapped to H37Rv Rv1396c YP_001287371.1 Mapped to H37Rv Rv1397c YP_001287372.1 Mapped to H37Rv Rv1398c YP_001287373.1 Mapped to H37Rv Rv1399c YP_001287374.1 Mapped to H37Rv Rv1400c YP_001287375.1 Mapped to H37Rv Rv1401 YP_001287376.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001287377.1 Mapped to H37Rv Rv1403c YP_001287378.1 Mapped to H37Rv Rv1404 YP_001287379.1 Mapped to H37Rv Rv1405c YP_001287380.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001287381.1 Mapped to H37Rv Rv1407 YP_001287382.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001287383.1 Mapped to H37Rv Rv1409 YP_001287384.1 Mapped to H37Rv Rv1410c YP_001287385.1 Mapped to H37Rv Rv1411c YP_001287386.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001287387.1 Mapped to H37Rv Rv1413 YP_001287388.1 Mapped to H37Rv Rv1414 YP_001287389.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_001287390.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001287391.1 Mapped to H37Rv Rv1417 YP_001287392.1 Mapped to H37Rv Rv1418 YP_001287393.1 Mapped to H37Rv Rv1419 YP_001287394.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001287395.1 Mapped to H37Rv Rv1421 YP_001287396.1 Mapped to H37Rv Rv1422 YP_001287397.1 Mapped to H37Rv Rv1423 YP_001287398.1 Mapped to H37Rv Rv1424c YP_001287399.1 Mapped to H37Rv Rv1425 YP_001287400.1 Mapped to H37Rv Rv1426c YP_001287401.1 activates fatty acids by binding to coenzyme A YP_001287402.1 Mapped to H37Rv Rv1428c YP_001287403.1 Mapped to H37Rv Rv1429 YP_001287404.1 Mapped to H37Rv Rv1430 YP_001287405.1 Mapped to H37Rv Rv1431 YP_001287406.1 Mapped to H37Rv Rv1432 YP_001287407.1 Mapped to H37Rv Rv1433 YP_001287408.1 Mapped to H37Rv Rv1435c YP_001287409.1 Mapped to H37Rv Rv1436 YP_001287410.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001287411.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001287412.1 Mapped to H37Rv Rv1439c YP_001287413.1 Mapped to H37Rv Rv1440 YP_001287414.1 Mapped to H37Rv Rv1441c YP_001287415.1 Mapped to H37Rv Rv1441c YP_001287416.1 Mapped to H37Rv Rv1441c YP_001287417.1 Mapped to H37Rv Rv1441c YP_001287418.1 Mapped to H37Rv Rv1441c YP_001287419.1 Mapped to H37Rv Rv1441c YP_001287420.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001287421.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate YP_001287422.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001287423.1 Mapped to H37Rv Rv1450c YP_001287424.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001287425.1 Mapped to H37Rv Rv1452c YP_001287426.1 Mapped to H37Rv Rv1453 YP_001287427.1 Mapped to H37Rv Rv1454c YP_001287428.1 Mapped to H37Rv Rv1455 YP_001287429.1 Mapped to H37Rv Rv1456c YP_001287430.1 Mapped to H37Rv Rv1457c YP_001287431.1 Mapped to H37Rv Rv1458c YP_001287432.1 Mapped to H37Rv Rv1459c YP_001287433.1 Mapped to H37Rv Rv1460 YP_001287434.1 Mapped to H37Rv Rv1461 YP_001287435.1 Mapped to H37Rv Rv1462 YP_001287436.1 Mapped to H37Rv Rv1463 YP_001287437.1 Mapped to H37Rv Rv1464 YP_001287438.1 Mapped to H37Rv Rv1465 YP_001287439.1 Mapped to H37Rv Rv1466 YP_001287440.1 Mapped to H37Rv Rv1467c YP_001287441.1 Mapped to H37Rv Rv1468c YP_001287442.1 Mapped to H37Rv Rv1469 YP_001287443.1 Mapped to H37Rv Rv1470 YP_001287444.1 Mapped to H37Rv Rv1471 YP_001287445.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001287446.1 Mapped to H37Rv Rv1473 YP_001287447.1 Mapped to H37Rv Rv1473A YP_001287448.1 Mapped to H37Rv Rv1474c YP_001287449.1 Catalyzes the conversion of citrate to isocitrate YP_001287450.1 Mapped to H37Rv Rv1476 YP_001287451.1 Mapped to H37Rv Rv1477 YP_001287452.1 Mapped to H37Rv Rv1478 YP_001287453.1 Mapped to H37Rv Rv1479 YP_001287454.1 Mapped to H37Rv Rv1480 YP_001287455.1 Mapped to H37Rv Rv1481 YP_001287456.1 Mapped to H37Rv Rv1482c YP_001287457.1 Mapped to H37Rv Rv1483 YP_001287458.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001287459.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001287460.1 Mapped to H37Rv Rv1486c YP_001287461.1 Mapped to H37Rv Rv1487 YP_001287462.1 Mapped to H37Rv Rv1488 YP_001287463.1 Mapped to H37Rv Rv1489 YP_001287464.1 Mapped to H37Rv Rv1489A YP_001287465.1 Mapped to H37Rv Rv1490 YP_001287466.1 Mapped to H37Rv Rv1491c YP_001287467.1 Mapped to H37Rv Rv1492 YP_001287468.1 MDM; functions in conversion of succinate to propionate YP_001287469.1 Mapped to H37Rv Rv1494 YP_001287470.1 Mapped to H37Rv Rv1495 YP_001287471.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001287472.1 Mapped to H37Rv Rv1497 YP_001287473.1 Mapped to H37Rv Rv1498c YP_001287474.1 Mapped to H37Rv Rv1498A YP_001287475.1 Mapped to H37Rv Rv1499 YP_001287476.1 Mapped to H37Rv Rv1500 YP_001287477.1 Mapped to H37Rv Rv1501 YP_001287478.1 Mapped to H37Rv Rv1502 YP_001287479.1 Mapped to H37Rv Rv1503c YP_001287480.1 Mapped to H37Rv Rv1504c YP_001287481.1 Mapped to H37Rv Rv1505c YP_001287482.1 Mapped to H37Rv Rv1506c YP_001287483.1 Mapped to H37Rv Rv1507c YP_001287484.1 Mapped to H37Rv Rv1507A YP_001287485.1 Mapped to H37Rv Rv1508c YP_001287486.1 Mapped to H37Rv Rv1508A YP_001287487.1 Mapped to H37Rv Rv1509 YP_001287488.1 Mapped to H37Rv Rv1510 YP_001287490.1 Mapped to H37Rv Rv1511 YP_001287491.1 Mapped to H37Rv Rv1512 YP_001287492.1 Mapped to H37Rv Rv1513 YP_001287493.1 Mapped to H37Rv Rv1514c YP_001287494.1 Mapped to H37Rv Rv1515c YP_001287495.1 Mapped to H37Rv Rv1516c YP_001287496.1 Mapped to H37Rv Rv1517 YP_001287497.1 Mapped to H37Rv Rv1518 YP_001287498.1 Mapped to H37Rv Rv1520 YP_001287499.1 activates fatty acids by binding to coenzyme A YP_001287500.1 Mapped to H37Rv Rv1522c YP_001287501.1 Mapped to H37Rv Rv1523 YP_001287502.1 Mapped to H37Rv Rv1524 YP_001287503.1 Mapped to H37Rv Rv1525 YP_001287504.1 Mapped to H37Rv Rv1526c YP_001287505.1 Mapped to H37Rv Rv1527c YP_001287506.1 Mapped to H37Rv Rv1528c YP_001287507.1 activates fatty acids by binding to coenzyme A YP_001287508.1 Mapped to H37Rv Rv1530 YP_001287509.1 Mapped to H37Rv Rv1531 YP_001287510.1 Mapped to H37Rv Rv1532c YP_001287511.1 Mapped to H37Rv Rv1533 YP_001287512.1 Mapped to H37Rv Rv1534 YP_001287513.1 Mapped to H37Rv Rv1535 YP_001287514.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_001287515.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001287516.1 Mapped to H37Rv Rv1538c YP_001287517.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001287518.1 Mapped to H37Rv Rv1540 YP_001287519.1 Mapped to H37Rv Rv1541c YP_001287520.1 Mapped to H37Rv Rv1542c YP_001287521.1 Mapped to H37Rv Rv1543 YP_001287522.1 Mapped to H37Rv Rv1544 YP_001287523.1 Mapped to H37Rv Rv1545 YP_001287524.1 Mapped to H37Rv Rv1546 YP_001287525.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001287526.1 Mapped to H37Rv Rv1548c YP_001287527.1 Mapped to H37Rv Rv1550 YP_001287528.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001287529.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001287530.1 Mapped to H37Rv Rv1553 YP_001287531.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001287532.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001287533.1 Mapped to H37Rv Rv1556 YP_001287534.1 Mapped to H37Rv Rv1557 YP_001287535.1 Mapped to H37Rv Rv1558 YP_001287536.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001287537.1 Mapped to H37Rv Rv1560 YP_001287538.1 Mapped to H37Rv Rv1561 YP_001287539.1 Mapped to H37Rv Rv1562c YP_001287540.1 Mapped to H37Rv Rv1563c YP_001287541.1 Mapped to H37Rv Rv1564c YP_001287542.1 Mapped to H37Rv Rv1565c YP_001287543.1 Mapped to H37Rv Rv1566c YP_001287544.1 Mapped to H37Rv Rv1567c YP_001287545.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001287546.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001287547.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001287548.1 Mapped to H37Rv Rv1571 YP_001287549.1 Mapped to H37Rv Rv1587c YP_001287550.1 Mapped to H37Rv Rv1588c YP_001287551.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_001287552.1 Mapped to H37Rv Rv1591 YP_001287553.1 Mapped to H37Rv Rv1592c YP_001287554.1 Mapped to H37Rv Rv1593c YP_001287555.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001287556.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001287557.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001287558.1 Mapped to H37Rv Rv1597 YP_001287559.1 Mapped to H37Rv Rv1598c YP_001287560.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001287561.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001287562.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001287563.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001287564.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis YP_001287565.1 Mapped to H37Rv Rv1604 YP_001287566.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001287567.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001287568.1 Mapped to H37Rv Rv1607 YP_001287569.1 Mapped to H37Rv Rv1608c YP_001287570.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001287571.1 Mapped to H37Rv Rv1610 YP_001287572.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001287573.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001287574.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001287575.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001287576.1 Mapped to H37Rv Rv1615 YP_001287577.1 Mapped to H37Rv Rv1616 YP_001287578.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001287579.1 Mapped to H37Rv Rv1618 YP_001287580.1 Mapped to H37Rv Rv1619 YP_001287581.1 Mapped to H37Rv Rv1620c YP_001287582.1 Mapped to H37Rv Rv1621c YP_001287583.1 Mapped to H37Rv Rv1622c YP_001287584.1 Mapped to H37Rv Rv1623c YP_001287585.1 Mapped to H37Rv Rv1624c YP_001287586.1 Mapped to H37Rv Rv1625c YP_001287587.1 Mapped to H37Rv Rv1626 YP_001287588.1 Mapped to H37Rv Rv1627c YP_001287589.1 Mapped to H37Rv Rv1628c YP_001287590.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001287591.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001287592.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain YP_001287593.1 Mapped to H37Rv Rv1632c YP_001287594.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001287595.1 Mapped to H37Rv Rv1634 YP_001287596.1 Mapped to H37Rv Rv1635c YP_001287597.1 Mapped to H37Rv Rv1636 YP_001287598.1 Mapped to H37Rv Rv1637c YP_001287599.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001287600.1 Mapped to H37Rv Rv1638A YP_001287601.1 Mapped to H37Rv Rv1639c YP_001287602.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001287603.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001287604.1 Mapped to H37Rv Rv1642 YP_001287605.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001287606.1 Mapped to H37Rv Rv1644 YP_001287607.1 Mapped to H37Rv Rv1645c YP_001287608.1 Mapped to H37Rv Rv1646 YP_001287609.1 Mapped to H37Rv Rv1647 YP_001287610.1 Mapped to H37Rv Rv1648 YP_001287611.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001287612.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001287613.1 Mapped to H37Rv Rv1651c YP_001287614.1 Mapped to H37Rv Rv1651c YP_001287615.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001287616.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001287617.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001287618.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001287619.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001287620.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001287621.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001287622.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001287623.1 Mapped to H37Rv Rv1660 YP_001287624.1 Mapped to H37Rv Rv1661 YP_001287625.1 Mapped to H37Rv Rv1662 YP_001287626.1 Mapped to H37Rv Rv1663 YP_001287627.1 Mapped to H37Rv Rv1664 YP_001287628.1 Mapped to H37Rv Rv1665 YP_001287629.1 Mapped to H37Rv Rv1666c YP_001287630.1 Mapped to H37Rv Rv1666c YP_001287631.1 Mapped to H37Rv Rv1669 YP_001287632.1 Mapped to H37Rv Rv1670 YP_001287633.1 Mapped to H37Rv Rv1671 YP_001287634.1 Mapped to H37Rv Rv1672c YP_001287635.1 Mapped to H37Rv Rv1673c YP_001287636.1 Mapped to H37Rv Rv1674c YP_001287637.1 Mapped to H37Rv Rv1675c YP_001287638.1 Mapped to H37Rv Rv1676 YP_001287639.1 Mapped to H37Rv Rv1677 YP_001287640.1 Mapped to H37Rv Rv1678 YP_001287641.1 Mapped to H37Rv Rv1679 YP_001287642.1 Mapped to H37Rv Rv1680 YP_001287643.1 Mapped to H37Rv Rv1681 YP_001287644.1 Mapped to H37Rv Rv1682 YP_001287645.1 activates fatty acids by binding to coenzyme A YP_001287646.1 Mapped to H37Rv Rv1685c YP_001287647.1 Mapped to H37Rv Rv1686c YP_001287648.1 Mapped to H37Rv Rv1687c YP_001287649.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_001287650.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001287651.1 Mapped to H37Rv Rv1690 YP_001287652.1 Mapped to H37Rv Rv1691 YP_001287653.1 Mapped to H37Rv Rv1692 YP_001287654.1 Mapped to H37Rv Rv1694 YP_001287655.1 catalyzes the phosphorylation of NAD to NADP YP_001287656.1 Mapped to H37Rv Rv1696 YP_001287657.1 Mapped to H37Rv Rv1697 YP_001287658.1 Mapped to H37Rv Rv1698 YP_001287659.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001287660.1 Mapped to H37Rv Rv1700 YP_001287661.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001287662.1 Mapped to H37Rv Rv1702c YP_001287663.1 Mapped to H37Rv Rv1703c YP_001287664.1 Mapped to H37Rv Rv1704c YP_001287665.1 Mapped to H37Rv Rv1705c YP_001287666.1 Mapped to H37Rv Rv1706c YP_001287667.1 Mapped to H37Rv Rv1707 YP_001287668.1 Mapped to H37Rv Rv1708 YP_001287669.1 Mapped to H37Rv Rv1709 YP_001287670.1 Mapped to H37Rv Rv1710 YP_001287671.1 Mapped to H37Rv Rv1711 YP_001287672.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001287673.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001287674.1 Mapped to H37Rv Rv1714 YP_001287675.1 Mapped to H37Rv Rv1715 YP_001287676.1 Mapped to H37Rv Rv1716 YP_001287677.1 Mapped to H37Rv Rv1717 YP_001287678.1 Mapped to H37Rv Rv1718 YP_001287679.1 Mapped to H37Rv Rv1719 YP_001287680.1 Mapped to H37Rv Rv1720c YP_001287681.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001287682.1 Mapped to H37Rv Rv1723 YP_001287685.1 Mapped to H37Rv Rv1725c YP_001287686.1 Mapped to H37Rv Rv1726 YP_001287687.1 Mapped to H37Rv Rv1727 YP_001287688.1 Mapped to H37Rv Rv1728c YP_001287689.1 Mapped to H37Rv Rv1729c YP_001287690.1 Mapped to H37Rv Rv1730c YP_001287691.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate YP_001287692.1 Mapped to H37Rv Rv1732c YP_001287693.1 Mapped to H37Rv Rv1733c YP_001287694.1 Mapped to H37Rv Rv1734c YP_001287695.1 Mapped to H37Rv Rv1735c YP_001287696.1 Mapped to H37Rv Rv1735c YP_001287697.1 Mapped to H37Rv Rv1736c YP_001287698.1 Mapped to H37Rv Rv1737c YP_001287699.1 Mapped to H37Rv Rv1738 YP_001287700.1 Mapped to H37Rv Rv1739c YP_001287701.1 Mapped to H37Rv Rv1740 YP_001287702.1 Mapped to H37Rv Rv1741 YP_001287703.1 Mapped to H37Rv Rv1742 YP_001287704.1 Mapped to H37Rv Rv1743 YP_001287705.1 Mapped to H37Rv Rv1744c YP_001287706.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001287707.1 Mapped to H37Rv Rv1746 YP_001287708.1 Mapped to H37Rv Rv1747 YP_001287709.1 Mapped to H37Rv Rv1748 YP_001287710.1 Mapped to H37Rv Rv1749c YP_001287711.1 activates fatty acids by binding to coenzyme A YP_001287712.1 Mapped to H37Rv Rv1751 YP_001287713.1 Mapped to H37Rv Rv1752 YP_001287714.1 Mapped to H37Rv Rv1753c YP_001287715.1 Mapped to H37Rv Rv1754c YP_001287716.1 Mapped to H37Rv Rv1756c YP_001287717.1 Mapped to H37Rv Rv1757c YP_001287718.1 Mapped to H37Rv Rv1757c YP_001287719.1 Mapped to H37Rv Rv1757c YP_001287720.1 Mapped to H37Rv Rv1758 YP_001287721.1 Mapped to H37Rv Rv1758 YP_001287724.1 Mapped to H37Rv Rv1759c YP_001287726.1 Mapped to H37Rv Rv1759c YP_001287727.1 Mapped to H37Rv Rv1760 YP_001287728.1 Mapped to H37Rv Rv1761c YP_001287729.1 Mapped to H37Rv Rv1762c YP_001287730.1 Mapped to H37Rv Rv1762c YP_001287731.1 Mapped to H37Rv Rv1762c YP_001287732.1 Mapped to H37Rv Rv1763 YP_001287733.1 Mapped to H37Rv Rv1764 YP_001287734.1 Mapped to H37Rv Rv1765A YP_001287735.1 Mapped to H37Rv Rv1766 YP_001287736.1 Mapped to H37Rv Rv1767 YP_001287737.1 Mapped to H37Rv Rv1768 YP_001287738.1 Mapped to H37Rv Rv1769 YP_001287739.1 Mapped to H37Rv Rv1770 YP_001287740.1 Mapped to H37Rv Rv1771 YP_001287741.1 Mapped to H37Rv Rv1772 YP_001287742.1 Mapped to H37Rv Rv1773c YP_001287743.1 Mapped to H37Rv Rv1774 YP_001287744.1 Mapped to H37Rv Rv1775 YP_001287745.1 Mapped to H37Rv Rv1776c YP_001287748.1 Mapped to H37Rv Rv1778c YP_001287749.1 Mapped to H37Rv Rv1779c YP_001287750.1 Mapped to H37Rv Rv1780 YP_001287751.1 Mapped to H37Rv Rv1781c YP_001287752.1 Mapped to H37Rv Rv1782 YP_001287753.1 Mapped to H37Rv Rv1782 YP_001287754.1 Mapped to H37Rv Rv1785c YP_001287755.1 Mapped to H37Rv Rv1786 YP_001287756.1 Mapped to H37Rv Rv1787 YP_001287757.1 Mapped to H37Rv Rv1788 YP_001287758.1 Mapped to H37Rv Rv1789 YP_001287759.1 Mapped to H37Rv Rv1790 YP_001287760.1 Mapped to H37Rv Rv1791 YP_001287761.1 Mapped to H37Rv Rv1793 YP_001287762.1 Mapped to H37Rv Rv1794 YP_001287763.1 Mapped to H37Rv Rv1795 YP_001287764.1 Mapped to H37Rv Rv1796 YP_001287765.1 Mapped to H37Rv Rv1797 YP_001287766.1 Mapped to H37Rv Rv1798 YP_001287767.1 Mapped to H37Rv Rv1799 YP_001287768.1 Mapped to H37Rv Rv1800 YP_001287769.1 Mapped to H37Rv Rv1801 YP_001287770.1 Mapped to H37Rv Rv1802 YP_001287771.1 Mapped to H37Rv Rv1803c YP_001287772.1 Mapped to H37Rv Rv1804c YP_001287773.1 Mapped to H37Rv Rv1806 YP_001287774.1 Mapped to H37Rv Rv1807 YP_001287775.1 Mapped to H37Rv Rv1808 YP_001287776.1 Mapped to H37Rv Rv1809 YP_001287777.1 Mapped to H37Rv Rv1810 YP_001287778.1 Mapped to H37Rv Rv1811 YP_001287779.1 Mapped to H37Rv Rv1812c YP_001287780.1 Mapped to H37Rv Rv1813c YP_001287781.1 Mapped to H37Rv Rv1814 YP_001287782.1 Mapped to H37Rv Rv1815 YP_001287783.1 Mapped to H37Rv Rv1816 YP_001287784.1 Mapped to H37Rv Rv1817 YP_001287785.1 Mapped to H37Rv Rv1818c YP_001287786.1 Mapped to H37Rv Rv1819c YP_001287787.1 Mapped to H37Rv Rv1820 YP_001287788.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins YP_001287789.1 Mapped to H37Rv Rv1822 YP_001287790.1 Mapped to H37Rv Rv1823 YP_001287791.1 Mapped to H37Rv Rv1824 YP_001287792.1 Mapped to H37Rv Rv1825 YP_001287793.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001287794.1 Mapped to H37Rv Rv1827 YP_001287795.1 Mapped to H37Rv Rv1828 YP_001287796.1 Mapped to H37Rv Rv1829 YP_001287797.1 Mapped to H37Rv Rv1830 YP_001287798.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001287799.1 Mapped to H37Rv Rv1833c YP_001287800.1 Mapped to H37Rv Rv1834 YP_001287801.1 Mapped to H37Rv Rv1835c YP_001287802.1 Mapped to H37Rv Rv1836c YP_001287803.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001287804.1 Mapped to H37Rv Rv1838c YP_001287805.1 Mapped to H37Rv Rv1840c YP_001287806.1 Mapped to H37Rv Rv1841c YP_001287807.1 Mapped to H37Rv Rv1842c YP_001287808.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001287809.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001287810.1 Mapped to H37Rv Rv1845c YP_001287811.1 Mapped to H37Rv Rv1846c YP_001287812.1 Mapped to H37Rv Rv1847 YP_001287813.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001287814.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta) YP_001287815.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001287816.1 Mapped to H37Rv Rv1851 YP_001287817.1 Mapped to H37Rv Rv1852 YP_001287818.1 Mapped to H37Rv Rv1853 YP_001287819.1 Mapped to H37Rv Rv1854c YP_001287820.1 Mapped to H37Rv Rv1855c YP_001287821.1 Mapped to H37Rv Rv1856c YP_001287822.1 Mapped to H37Rv Rv1857 YP_001287823.1 Mapped to H37Rv Rv1858 YP_001287824.1 Mapped to H37Rv Rv1859 YP_001287825.1 Mapped to H37Rv Rv1860 YP_001287826.1 Mapped to H37Rv Rv1861 YP_001287827.1 Mapped to H37Rv Rv1862 YP_001287828.1 Mapped to H37Rv Rv1863c YP_001287829.1 Mapped to H37Rv Rv1864c YP_001287830.1 Mapped to H37Rv Rv1865c YP_001287831.1 Mapped to H37Rv Rv1866 YP_001287832.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001287833.1 Mapped to H37Rv Rv1868 YP_001287834.1 Mapped to H37Rv Rv1869c YP_001287835.1 Mapped to H37Rv Rv1870c YP_001287836.1 Mapped to H37Rv Rv1871c YP_001287837.1 Mapped to H37Rv Rv1872c YP_001287838.1 Mapped to H37Rv Rv1873 YP_001287839.1 Mapped to H37Rv Rv1874 YP_001287840.1 Mapped to H37Rv Rv1875 YP_001287841.1 Mapped to H37Rv Rv1876 YP_001287842.1 Mapped to H37Rv Rv1877 YP_001287843.1 Mapped to H37Rv Rv1878 YP_001287844.1 Mapped to H37Rv Rv1879 YP_001287845.1 Mapped to H37Rv Rv1880c YP_001287846.1 Mapped to H37Rv Rv1881c YP_001287847.1 Mapped to H37Rv Rv1882c YP_001287848.1 Mapped to H37Rv Rv1883c YP_001287849.1 Mapped to H37Rv Rv1884c YP_001287850.1 catalyzes the interconversion of chorismate to prephenate YP_001287851.1 Mapped to H37Rv Rv1886c YP_001287852.1 Mapped to H37Rv Rv1887 YP_001287853.1 Mapped to H37Rv Rv1888c YP_001287854.1 Mapped to H37Rv Rv1889c YP_001287855.1 Mapped to H37Rv Rv1890c YP_001287856.1 Mapped to H37Rv Rv1891 YP_001287857.1 Mapped to H37Rv Rv1892 YP_001287858.1 Mapped to H37Rv Rv1893 YP_001287859.1 Mapped to H37Rv Rv1894c YP_001287861.1 Mapped to H37Rv Rv1895 YP_001287862.1 Mapped to H37Rv Rv1896c YP_001287863.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001287864.1 Mapped to H37Rv Rv1898 YP_001287865.1 Mapped to H37Rv Rv1899c YP_001287866.1 Mapped to H37Rv Rv1900c YP_001287867.1 Mapped to H37Rv Rv1901 YP_001287868.1 Mapped to H37Rv Rv1902c YP_001287869.1 Mapped to H37Rv Rv1903 YP_001287870.1 Mapped to H37Rv Rv1904 YP_001287871.1 Mapped to H37Rv Rv1905c YP_001287872.1 Mapped to H37Rv Rv1906c YP_001287873.1 Mapped to H37Rv Rv1907c YP_001287874.1 Mapped to H37Rv Rv1908c YP_001287875.1 Mapped to H37Rv Rv1909c YP_001287876.1 Mapped to H37Rv Rv1910c YP_001287877.1 Mapped to H37Rv Rv1911c YP_001287878.1 Mapped to H37Rv Rv1912c YP_001287879.1 Mapped to H37Rv Rv1913 YP_001287880.1 Mapped to H37Rv Rv1914c YP_001287881.1 Mapped to H37Rv Rv1915 YP_001287882.1 Mapped to H37Rv Rv1916 YP_001287883.1 Mapped to H37Rv Rv1917c YP_001287884.1 Mapped to H37Rv Rv1918c YP_001287885.1 Mapped to H37Rv Rv1919c YP_001287886.1 Mapped to H37Rv Rv1920 YP_001287887.1 Mapped to H37Rv Rv1921c YP_001287888.1 Mapped to H37Rv Rv1922 YP_001287889.1 Mapped to H37Rv Rv1923 YP_001287890.1 Mapped to H37Rv Rv1924c YP_001287891.1 activates fatty acids by binding to coenzyme A YP_001287892.1 Mapped to H37Rv Rv1926c YP_001287893.1 Mapped to H37Rv Rv1927 YP_001287894.1 Mapped to H37Rv Rv1928c YP_001287895.1 Mapped to H37Rv Rv1929c YP_001287896.1 Mapped to H37Rv Rv1930c YP_001287897.1 Mapped to H37Rv Rv1931c YP_001287898.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001287899.1 Mapped to H37Rv Rv1933c YP_001287900.1 Mapped to H37Rv Rv1934c YP_001287901.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001287902.1 Mapped to H37Rv Rv1936 YP_001287903.1 Mapped to H37Rv Rv1937 YP_001287904.1 Mapped to H37Rv Rv1938 YP_001287905.1 Mapped to H37Rv Rv1939 YP_001287906.1 Mapped to H37Rv Rv1940 YP_001287907.1 Mapped to H37Rv Rv1941 YP_001287908.1 Mapped to H37Rv Rv1942c YP_001287909.1 Mapped to H37Rv Rv1943c YP_001287910.1 Mapped to H37Rv Rv1944c YP_001287911.1 Mapped to H37Rv Rv1945 YP_001287912.1 Mapped to H37Rv Rv1946c YP_001287913.1 Mapped to H37Rv Rv1947 YP_001287914.1 Mapped to H37Rv Rv1948c YP_001287915.1 Mapped to H37Rv Rv1949c YP_001287916.1 Mapped to H37Rv Rv1950c YP_001287917.1 Mapped to H37Rv Rv1951c YP_001287918.1 Mapped to H37Rv Rv1952 YP_001287919.1 Mapped to H37Rv Rv1953 YP_001287920.1 Mapped to H37Rv Rv1955 YP_001287921.1 Mapped to H37Rv Rv1956 YP_001287922.1 Mapped to H37Rv Rv1957 YP_001287923.1 Mapped to H37Rv Rv1958c YP_001287924.1 Mapped to H37Rv Rv1959c YP_001287925.1 Mapped to H37Rv Rv1960c YP_001287926.1 Mapped to H37Rv Rv1961 YP_001287927.1 Mapped to H37Rv Rv1962c YP_001287928.1 Mapped to H37Rv Rv1962c YP_001287929.1 Mapped to H37Rv Rv1963c YP_001287931.1 Mapped to H37Rv Rv1964 YP_001287932.1 Mapped to H37Rv Rv1964 YP_001287933.1 Mapped to H37Rv Rv1965 YP_001287934.1 Mapped to H37Rv Rv1966 YP_001287935.1 Mapped to H37Rv Rv1967 YP_001287936.1 Mapped to H37Rv Rv1968 YP_001287937.1 Mapped to H37Rv Rv1969 YP_001287938.1 Mapped to H37Rv Rv1970 YP_001287939.1 Mapped to H37Rv Rv1971 YP_001287940.1 Mapped to H37Rv Rv1972 YP_001287941.1 Mapped to H37Rv Rv1973 YP_001287942.1 Mapped to H37Rv Rv1974 YP_001287943.1 Mapped to H37Rv Rv1975 YP_001287944.1 Mapped to H37Rv Rv1976c YP_001287945.1 Mapped to H37Rv Rv1977 YP_001287946.1 Mapped to H37Rv Rv1978 YP_001287947.1 Mapped to H37Rv Rv1979c YP_001287948.1 Mapped to H37Rv Rv1980c YP_001287949.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001287950.1 Mapped to H37Rv Rv1982c YP_001287951.1 Mapped to H37Rv Rv1983 YP_001287952.1 Mapped to H37Rv Rv1984c YP_001287953.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001287954.1 Mapped to H37Rv Rv1986 YP_001287955.1 Mapped to H37Rv Rv1987 YP_001287956.1 Mapped to H37Rv Rv1988 YP_001287957.1 Mapped to H37Rv Rv1989c YP_001287958.1 Mapped to H37Rv Rv1990c YP_001287959.1 Mapped to H37Rv Rv1990A YP_001287960.1 Mapped to H37Rv Rv1991c YP_001287961.1 Mapped to H37Rv Rv1992c YP_001287962.1 Mapped to H37Rv Rv1993c YP_001287963.1 Mapped to H37Rv Rv1994c YP_001287964.1 Mapped to H37Rv Rv1995 YP_001287965.1 Mapped to H37Rv Rv1996 YP_001287966.1 Mapped to H37Rv Rv1997 YP_001287967.1 Mapped to H37Rv Rv1998c YP_001287968.1 Mapped to H37Rv Rv1999c YP_001287969.1 Mapped to H37Rv Rv2000 YP_001287970.1 Mapped to H37Rv Rv2001 YP_001287971.1 Mapped to H37Rv Rv2002 YP_001287972.1 Mapped to H37Rv Rv2003c YP_001287973.1 Mapped to H37Rv Rv2004c YP_001287974.1 Mapped to H37Rv Rv2005c YP_001287975.1 Mapped to H37Rv Rv2006 YP_001287976.1 Mapped to H37Rv Rv2007c YP_001287977.1 Mapped to H37Rv Rv2008c YP_001287978.1 Mapped to H37Rv Rv2009 YP_001287979.1 Mapped to H37Rv Rv2010 YP_001287980.1 Mapped to H37Rv Rv2011c YP_001287981.1 Mapped to H37Rv Rv2012 YP_001287982.1 Mapped to H37Rv Rv2013 YP_001287983.1 Mapped to H37Rv Rv2014 YP_001287986.1 Mapped to H37Rv Rv2016 YP_001287987.1 Mapped to H37Rv Rv2017 YP_001287988.1 Mapped to H37Rv Rv2018 YP_001287989.1 Mapped to H37Rv Rv2019 YP_001287995.1 Mapped to H37Rv Rv2025c YP_001287996.1 Mapped to H37Rv Rv2026c YP_001287997.1 Mapped to H37Rv Rv2027c YP_001287998.1 Mapped to H37Rv Rv2028c YP_001287999.1 Mapped to H37Rv Rv2029c YP_001288000.1 Mapped to H37Rv Rv2030c YP_001288001.1 Mapped to H37Rv Rv2031c YP_001288002.1 Mapped to H37Rv Rv2032 YP_001288003.1 Mapped to H37Rv Rv2033c YP_001288004.1 Mapped to H37Rv Rv2034 YP_001288005.1 Mapped to H37Rv Rv2035 YP_001288006.1 Mapped to H37Rv Rv2036 YP_001288007.1 Mapped to H37Rv Rv2037c YP_001288008.1 Mapped to H37Rv Rv2038c YP_001288009.1 Mapped to H37Rv Rv2039c YP_001288010.1 Mapped to H37Rv Rv2040c YP_001288011.1 Mapped to H37Rv Rv2041c YP_001288012.1 Mapped to H37Rv Rv2042c YP_001288013.1 Mapped to H37Rv Rv2043c YP_001288014.1 Mapped to H37Rv Rv2044c YP_001288015.1 Mapped to H37Rv Rv2045c YP_001288016.1 Mapped to H37Rv Rv2046 YP_001288017.1 Mapped to H37Rv Rv2047c YP_001288018.1 Mapped to H37Rv Rv2048c YP_001288019.1 Mapped to H37Rv Rv2049c YP_001288020.1 Mapped to H37Rv Rv2050 YP_001288021.1 Mapped to H37Rv Rv2051c YP_001288022.1 Mapped to H37Rv Rv2052c YP_001288023.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001288024.1 Mapped to H37Rv Rv2054 YP_001288025.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001288026.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001288027.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001288028.1 required for 70S ribosome assembly YP_001288029.1 Mapped to H37Rv Rv2059 YP_001288030.1 Mapped to H37Rv Rv2061c YP_001288031.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001288032.1 Mapped to H37Rv Rv2063 YP_001288033.1 Mapped to H37Rv Rv2064 YP_001288034.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001288035.1 Mapped to H37Rv Rv2066 YP_001288036.1 Mapped to H37Rv Rv2067c YP_001288037.1 Mapped to H37Rv Rv2068c YP_001288038.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001288039.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001288040.1 Mapped to H37Rv Rv2071c YP_001288041.1 Mapped to H37Rv Rv2072c YP_001288042.1 Mapped to H37Rv Rv2073c YP_001288043.1 Mapped to H37Rv Rv2074 YP_001288044.1 Mapped to H37Rv Rv2075c YP_001288045.1 Mapped to H37Rv Rv2077c YP_001288047.1 Mapped to H37Rv Rv2077c YP_001288049.1 Mapped to H37Rv Rv2079 YP_001288050.1 Mapped to H37Rv Rv2080 YP_001288051.1 Mapped to H37Rv Rv2081c YP_001288052.1 Mapped to H37Rv Rv2082 YP_001288053.1 Mapped to H37Rv Rv2083 YP_001288054.1 Mapped to H37Rv Rv2084 YP_001288055.1 Mapped to H37Rv Rv2086 YP_001288056.1 Mapped to H37Rv Rv2088 YP_001288057.1 Mapped to H37Rv Rv2089c YP_001288058.1 Mapped to H37Rv Rv2090 YP_001288059.1 Mapped to H37Rv Rv2091c YP_001288060.1 Mapped to H37Rv Rv2092c YP_001288061.1 Mapped to H37Rv Rv2093c YP_001288062.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001288063.1 Mapped to H37Rv Rv2095c YP_001288064.1 Mapped to H37Rv Rv2096c YP_001288065.1 Mapped to H37Rv Rv2097c YP_001288066.1 Mapped to H37Rv Rv2098c YP_001288067.1 Mapped to H37Rv Rv2100 YP_001288068.1 Mapped to H37Rv Rv2101 YP_001288069.1 Mapped to H37Rv Rv2102 YP_001288070.1 Mapped to H37Rv Rv2103c YP_001288071.1 Mapped to H37Rv Rv2104c YP_001288072.1 Mapped to H37Rv Rv2104c YP_001288073.1 Mapped to H37Rv Rv2108 YP_001288074.1 Mapped to H37Rv Rv2109c YP_001288075.1 Mapped to H37Rv Rv2110c YP_001288076.1 Mapped to H37Rv Rv2111c YP_001288077.1 Mapped to H37Rv Rv2112c YP_001288078.1 Mapped to H37Rv Rv2113 YP_001288079.1 Mapped to H37Rv Rv2114 YP_001288080.1 Mapped to H37Rv Rv2115c YP_001288081.1 Mapped to H37Rv Rv2116 YP_001288082.1 Mapped to H37Rv Rv2117 YP_001288083.1 Mapped to H37Rv Rv2118c YP_001288084.1 Mapped to H37Rv Rv2119 YP_001288085.1 Mapped to H37Rv Rv2120c YP_001288086.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001288087.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001288088.1 Mapped to H37Rv Rv2123 YP_001288089.1 Mapped to H37Rv Rv2124c YP_001288090.1 Mapped to H37Rv Rv2125 YP_001288091.1 Mapped to H37Rv Rv2126c YP_001288092.1 Mapped to H37Rv Rv2127 YP_001288093.1 Mapped to H37Rv Rv2129c YP_001288094.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001288095.1 Mapped to H37Rv Rv2131c YP_001288096.1 Mapped to H37Rv Rv2133c YP_001288097.1 Mapped to H37Rv Rv2134c YP_001288098.1 Mapped to H37Rv Rv2135c YP_001288099.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001288100.1 Mapped to H37Rv Rv2137c YP_001288101.1 Mapped to H37Rv Rv2138 YP_001288102.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001288103.1 Mapped to H37Rv Rv2140c YP_001288104.1 Mapped to H37Rv Rv2141c YP_001288105.1 Mapped to H37Rv Rv2142c YP_001288106.1 Mapped to H37Rv Rv2143 YP_001288107.1 Mapped to H37Rv Rv2144c YP_001288108.1 Mapped to H37Rv Rv2145c YP_001288109.1 Mapped to H37Rv Rv2146c YP_001288110.1 Mapped to H37Rv Rv2147c YP_001288111.1 Mapped to H37Rv Rv2148c YP_001288112.1 Mapped to H37Rv Rv2149c YP_001288113.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001288114.1 Mapped to H37Rv Rv2151c YP_001288115.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001288116.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001288117.1 Mapped to H37Rv Rv2154c YP_001288118.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001288119.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001288120.1 Mapped to H37Rv Rv2157c YP_001288121.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001288122.1 Mapped to H37Rv Rv2159c YP_001288123.1 Mapped to H37Rv Rv2160A YP_001288124.1 Mapped to H37Rv Rv2161c YP_001288125.1 Mapped to H37Rv Rv2162c YP_001288126.1 Mapped to H37Rv Rv2163c YP_001288127.1 Mapped to H37Rv Rv2164c YP_001288128.1 Mapped to H37Rv Rv2165c YP_001288129.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001288130.1 Mapped to H37Rv Rv2169c YP_001288131.1 Mapped to H37Rv Rv2170 YP_001288132.1 Mapped to H37Rv Rv2171 YP_001288133.1 Mapped to H37Rv Rv2172c YP_001288134.1 Mapped to H37Rv Rv2173 YP_001288135.1 Mapped to H37Rv Rv2174 YP_001288136.1 Mapped to H37Rv Rv2175c YP_001288137.1 Mapped to H37Rv Rv2176 YP_001288138.1 Mapped to H37Rv Rv2177c YP_001288139.1 Mapped to H37Rv Rv2178c YP_001288140.1 Mapped to H37Rv Rv2179c YP_001288141.1 Mapped to H37Rv Rv2180c YP_001288142.1 Mapped to H37Rv Rv2181 YP_001288143.1 Mapped to H37Rv Rv2182c YP_001288144.1 Mapped to H37Rv Rv2183c YP_001288145.1 Mapped to H37Rv Rv2184c YP_001288146.1 Mapped to H37Rv Rv2185c YP_001288147.1 Mapped to H37Rv Rv2186c YP_001288148.1 Mapped to H37Rv Rv2187 YP_001288149.1 Mapped to H37Rv Rv2188c YP_001288150.1 Mapped to H37Rv Rv2189c YP_001288151.1 Mapped to H37Rv Rv2190c YP_001288152.1 contains 3'-5'exonuclease domain YP_001288153.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001288154.1 Mapped to H37Rv Rv2193 YP_001288155.1 Mapped to H37Rv Rv2194 YP_001288156.1 Mapped to H37Rv Rv2195 YP_001288157.1 Mapped to H37Rv Rv2196 YP_001288158.1 Mapped to H37Rv Rv2197c YP_001288159.1 Mapped to H37Rv Rv2198c YP_001288160.1 Mapped to H37Rv Rv2199c YP_001288161.1 Mapped to H37Rv Rv2200c YP_001288162.1 Mapped to H37Rv Rv2201 YP_001288163.1 Mapped to H37Rv Rv2202c YP_001288164.1 Mapped to H37Rv Rv2203 YP_001288165.1 Mapped to H37Rv Rv2204c YP_001288166.1 Mapped to H37Rv Rv2205c YP_001288167.1 Mapped to H37Rv Rv2206 YP_001288168.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001288169.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001288170.1 Mapped to H37Rv Rv2209 YP_001288171.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001288172.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001288173.1 Mapped to H37Rv Rv2212 YP_001288174.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001288175.1 Mapped to H37Rv Rv2214c YP_001288176.1 Mapped to H37Rv Rv2215 YP_001288177.1 Mapped to H37Rv Rv2216 YP_001288178.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001288179.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001288180.1 Mapped to H37Rv Rv2219 YP_001288181.1 Mapped to H37Rv Rv2219A YP_001288182.1 Mapped to H37Rv Rv2220 YP_001288183.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001288184.1 Mapped to H37Rv Rv2222c YP_001288185.1 Mapped to H37Rv Rv2223c YP_001288186.1 Mapped to H37Rv Rv2224c YP_001288187.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001288188.1 Mapped to H37Rv Rv2226 YP_001288189.1 Mapped to H37Rv Rv2227 YP_001288190.1 Mapped to H37Rv Rv2228c YP_001288191.1 Mapped to H37Rv Rv2229c YP_001288192.1 Mapped to H37Rv Rv2230c YP_001288193.1 Mapped to H37Rv Rv2231c YP_001288195.1 Mapped to H37Rv Rv2232 YP_001288196.1 Mapped to H37Rv Rv2234 YP_001288197.1 Mapped to H37Rv Rv2235 YP_001288198.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001288199.1 Mapped to H37Rv Rv2237 YP_001288200.1 Mapped to H37Rv Rv2238c YP_001288201.1 Mapped to H37Rv Rv2239c YP_001288202.1 Mapped to H37Rv Rv2240c YP_001288203.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001288204.1 Mapped to H37Rv Rv2242 YP_001288205.1 Mapped to H37Rv Rv2243 YP_001288206.1 carries the fatty acid chain in fatty acid biosynthesis YP_001288207.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001288208.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001288209.1 Mapped to H37Rv Rv2247 YP_001288210.1 Mapped to H37Rv Rv2248 YP_001288211.1 Mapped to H37Rv Rv2249c YP_001288212.1 Mapped to H37Rv Rv2250c YP_001288213.1 Mapped to H37Rv Rv2250A YP_001288214.1 involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids YP_001288215.1 Mapped to H37Rv Rv2253 YP_001288216.1 Mapped to H37Rv Rv2254c YP_001288217.1 Mapped to H37Rv Rv2256c YP_001288218.1 Mapped to H37Rv Rv2257c YP_001288219.1 Mapped to H37Rv Rv2258c YP_001288220.1 Mapped to H37Rv Rv2259 YP_001288221.1 Mapped to H37Rv Rv2260 YP_001288222.1 Mapped to H37Rv Rv2263 YP_001288223.1 Mapped to H37Rv Rv2263 YP_001288224.1 Mapped to H37Rv Rv2264c YP_001288225.1 Mapped to H37Rv Rv2265 YP_001288226.1 Mapped to H37Rv Rv2266 YP_001288227.1 Mapped to H37Rv Rv2267c YP_001288228.1 Mapped to H37Rv Rv2268c YP_001288229.1 Mapped to H37Rv Rv2270 YP_001288230.1 Mapped to H37Rv Rv2271 YP_001288231.1 Mapped to H37Rv Rv2272 YP_001288232.1 Mapped to H37Rv Rv2273 YP_001288233.1 Mapped to H37Rv Rv2275 YP_001288234.1 Mapped to H37Rv Rv2276 YP_001288235.1 Mapped to H37Rv Rv2277c YP_001288236.1 Mapped to H37Rv Rv2280 YP_001288237.1 Mapped to H37Rv Rv2281 YP_001288238.1 Mapped to H37Rv Rv2282c YP_001288239.1 Mapped to H37Rv Rv2284 YP_001288240.1 Mapped to H37Rv Rv2285 YP_001288241.1 Mapped to H37Rv Rv2286c YP_001288242.1 Mapped to H37Rv Rv2287 YP_001288243.1 Mapped to H37Rv Rv2288 YP_001288244.1 Mapped to H37Rv Rv2290 YP_001288245.1 Mapped to H37Rv Rv2291 YP_001288246.1 Mapped to H37Rv Rv2292c YP_001288247.1 Mapped to H37Rv Rv2293c YP_001288248.1 Mapped to H37Rv Rv2294 YP_001288249.1 Mapped to H37Rv Rv2295 YP_001288250.1 Mapped to H37Rv Rv2296 YP_001288251.1 Mapped to H37Rv Rv2297 YP_001288252.1 Mapped to H37Rv Rv2298 YP_001288253.1 molecular chaperone YP_001288254.1 Mapped to H37Rv Rv2300c YP_001288255.1 Mapped to H37Rv Rv2301 YP_001288256.1 Mapped to H37Rv Rv2302 YP_001288257.1 Mapped to H37Rv Rv2303c YP_001288258.1 Mapped to H37Rv Rv2305 YP_001288259.1 Mapped to H37Rv Rv2305 YP_001288260.1 Mapped to H37Rv Rv2307c YP_001288261.1 Mapped to H37Rv Rv2307A YP_001288262.1 Mapped to H37Rv Rv2307B YP_001288263.1 Mapped to H37Rv Rv2308 YP_001288264.1 Mapped to H37Rv Rv2309c YP_001288265.1 Mapped to H37Rv Rv2310 YP_001288266.1 Mapped to H37Rv Rv2311 YP_001288267.1 Mapped to H37Rv Rv2313c YP_001288268.1 Mapped to H37Rv Rv2314c YP_001288269.1 Mapped to H37Rv Rv2315c YP_001288270.1 Mapped to H37Rv Rv2316 YP_001288271.1 Mapped to H37Rv Rv2317 YP_001288272.1 Mapped to H37Rv Rv2318 YP_001288273.1 Mapped to H37Rv Rv2319c YP_001288274.1 Mapped to H37Rv Rv2320c YP_001288275.1 Mapped to H37Rv Rv2321c YP_001288276.1 Mapped to H37Rv Rv2322c YP_001288277.1 Mapped to H37Rv Rv2323c YP_001288278.1 Mapped to H37Rv Rv2324 YP_001288279.1 Mapped to H37Rv Rv2325c YP_001288280.1 Mapped to H37Rv Rv2326c YP_001288281.1 Mapped to H37Rv Rv2327 YP_001288282.1 Mapped to H37Rv Rv2328 YP_001288283.1 Mapped to H37Rv Rv2329c YP_001288284.1 Mapped to H37Rv Rv2330c YP_001288285.1 Mapped to H37Rv Rv2331 YP_001288286.1 Mapped to H37Rv Rv2331A YP_001288287.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001288288.1 Mapped to H37Rv Rv2333c YP_001288289.1 Mapped to H37Rv Rv2334 YP_001288290.1 Mapped to H37Rv Rv2335 YP_001288291.1 Mapped to H37Rv Rv2336 YP_001288292.1 Mapped to H37Rv Rv2337c YP_001288293.1 Mapped to H37Rv Rv2338c YP_001288294.1 Mapped to H37Rv Rv2339 YP_001288295.1 Mapped to H37Rv Rv2340c YP_001288296.1 Mapped to H37Rv Rv2341 YP_001288297.1 Mapped to H37Rv Rv2342 YP_001288298.1 synthesizes RNA primers at the replication forks YP_001288299.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001288300.1 Mapped to H37Rv Rv2345 YP_001288301.1 Mapped to H37Rv Rv2346c YP_001288302.1 Mapped to H37Rv Rv2347c YP_001288303.1 Mapped to H37Rv Rv2348c YP_001288304.1 Mapped to H37Rv Rv2349c YP_001288305.1 Mapped to H37Rv Rv2350c YP_001288306.1 Mapped to H37Rv Rv2351c YP_001288307.1 Mapped to H37Rv Rv2352c YP_001288310.1 Mapped to H37Rv Rv2353c YP_001288311.1 Mapped to H37Rv Rv2354 YP_001288312.1 Mapped to H37Rv Rv2355 YP_001288313.1 Mapped to H37Rv Rv2356c YP_001288314.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001288315.1 Mapped to H37Rv Rv2358 YP_001288316.1 Mapped to H37Rv Rv2359 YP_001288317.1 Mapped to H37Rv Rv2360c YP_001288318.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001288319.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001288320.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001288321.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001288322.1 Mapped to H37Rv Rv2365c YP_001288323.1 Mapped to H37Rv Rv2366c YP_001288324.1 Mapped to H37Rv Rv2367c YP_001288325.1 Mapped to H37Rv Rv2368c YP_001288326.1 Mapped to H37Rv Rv2370c YP_001288327.1 Mapped to H37Rv Rv2371 YP_001288328.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001288329.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001288330.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001288331.1 Mapped to H37Rv Rv2375 YP_001288332.1 Mapped to H37Rv Rv2376c YP_001288333.1 Mapped to H37Rv Rv2377c YP_001288334.1 Mapped to H37Rv Rv2378c YP_001288335.1 Mapped to H37Rv Rv2379c YP_001288336.1 Mapped to H37Rv Rv2380c YP_001288337.1 Mapped to H37Rv Rv2381c YP_001288338.1 Mapped to H37Rv Rv2382c YP_001288339.1 Mapped to H37Rv Rv2383c YP_001288340.1 Mapped to H37Rv Rv2384 YP_001288341.1 Mapped to H37Rv Rv2385 YP_001288342.1 catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function YP_001288343.1 Mapped to H37Rv Rv2387 YP_001288344.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001288345.1 Mapped to H37Rv Rv2389c YP_001288348.1 Mapped to H37Rv Rv2391 YP_001288349.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001288350.1 Mapped to H37Rv Rv2393 YP_001288351.1 Mapped to H37Rv Rv2394 YP_001288352.1 Mapped to H37Rv Rv2395 YP_001288353.1 Mapped to H37Rv Rv2396 YP_001288354.1 Mapped to H37Rv Rv2397c YP_001288355.1 Mapped to H37Rv Rv2398c YP_001288356.1 Mapped to H37Rv Rv2399c YP_001288357.1 Mapped to H37Rv Rv2400c YP_001288358.1 Mapped to H37Rv Rv2401A YP_001288359.1 Mapped to H37Rv Rv2402 YP_001288360.1 Mapped to H37Rv Rv2403c YP_001288361.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001288362.1 Mapped to H37Rv Rv2405 YP_001288363.1 Mapped to H37Rv Rv2406c YP_001288364.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001288365.1 Mapped to H37Rv Rv2408 YP_001288366.1 Mapped to H37Rv Rv2409c YP_001288367.1 Mapped to H37Rv Rv2410c YP_001288368.1 Mapped to H37Rv Rv2411c YP_001288369.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001288370.1 Mapped to H37Rv Rv2413c YP_001288371.1 Mapped to H37Rv Rv2414c YP_001288372.1 Mapped to H37Rv Rv2415c YP_001288373.1 Mapped to H37Rv Rv2416c YP_001288374.1 Mapped to H37Rv Rv2417c YP_001288375.1 Mapped to H37Rv Rv2418c YP_001288376.1 Mapped to H37Rv Rv2419c YP_001288377.1 Mapped to H37Rv Rv2420c YP_001288378.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001288379.1 Mapped to H37Rv Rv2422 YP_001288380.1 Mapped to H37Rv Rv2423 YP_001288381.1 Mapped to H37Rv Rv2424c YP_001288382.1 Mapped to H37Rv Rv2425c YP_001288383.1 Mapped to H37Rv Rv2426c YP_001288384.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001288385.1 Mapped to H37Rv Rv2428 YP_001288386.1 Mapped to H37Rv Rv2429 YP_001288387.1 Mapped to H37Rv Rv2430c YP_001288388.1 Mapped to H37Rv Rv2431c YP_001288389.1 Mapped to H37Rv Rv2432c YP_001288390.1 Mapped to H37Rv Rv2434c YP_001288391.1 Mapped to H37Rv Rv2435c YP_001288392.1 Mapped to H37Rv Rv2436 YP_001288393.1 Mapped to H37Rv Rv2437 YP_001288394.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001288395.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001288396.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001288397.1 involved in the peptidyltransferase reaction during translation YP_001288398.1 Mapped to H37Rv Rv2442c YP_001288399.1 Mapped to H37Rv Rv2443 YP_001288400.1 Mapped to H37Rv Rv2444c YP_001288401.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001288402.1 Mapped to H37Rv Rv2447c YP_001288403.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001288404.1 Mapped to H37Rv Rv2449c YP_001288405.1 Mapped to H37Rv Rv2450c YP_001288406.1 Mapped to H37Rv Rv2451 YP_001288407.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis YP_001288408.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_001288409.1 Mapped to H37Rv Rv2455c YP_001288410.1 Mapped to H37Rv Rv2456c YP_001288411.1 binds and unfolds substrates as part of the ClpXP protease YP_001288412.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_001288413.1 Mapped to H37Rv Rv2459 YP_001288414.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001288415.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001288416.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001288417.1 Mapped to H37Rv Rv2463 YP_001288418.1 Mapped to H37Rv Rv2464c YP_001288419.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001288420.1 Mapped to H37Rv Rv2466c YP_001288421.1 Mapped to H37Rv Rv2467 YP_001288422.1 Mapped to H37Rv Rv2468c YP_001288423.1 Mapped to H37Rv Rv2469c YP_001288424.1 Mapped to H37Rv Rv2470 YP_001288425.1 Mapped to H37Rv Rv2471 YP_001288426.1 Mapped to H37Rv Rv2473 YP_001288427.1 Mapped to H37Rv Rv2474c YP_001288428.1 Mapped to H37Rv Rv2475c YP_001288429.1 Mapped to H37Rv Rv2476c YP_001288430.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001288431.1 Mapped to H37Rv Rv2478c YP_001288432.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001288433.1 Mapped to H37Rv Rv2483c YP_001288434.1 Mapped to H37Rv Rv2484c YP_001288435.1 Mapped to H37Rv Rv2485c YP_001288436.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001288437.1 Mapped to H37Rv Rv2487c YP_001288438.1 Mapped to H37Rv Rv2487c YP_001288439.1 Mapped to H37Rv Rv2488c YP_001288440.1 Mapped to H37Rv Rv2489c YP_001288441.1 Mapped to H37Rv Rv2490c YP_001288442.1 Mapped to H37Rv Rv2490c YP_001288443.1 Mapped to H37Rv Rv2491 YP_001288444.1 Mapped to H37Rv Rv2492 YP_001288445.1 Mapped to H37Rv Rv2494 YP_001288446.1 Mapped to H37Rv Rv2495c YP_001288447.1 Mapped to H37Rv Rv2496c YP_001288448.1 Mapped to H37Rv Rv2497c YP_001288449.1 Mapped to H37Rv Rv2498c YP_001288450.1 Mapped to H37Rv Rv2499c YP_001288451.1 Mapped to H37Rv Rv2500c YP_001288452.1 Mapped to H37Rv Rv2501c YP_001288453.1 Mapped to H37Rv Rv2502c YP_001288454.1 Mapped to H37Rv Rv2503c YP_001288455.1 Mapped to H37Rv Rv2504c YP_001288456.1 activates fatty acids by binding to coenzyme A YP_001288457.1 Mapped to H37Rv Rv2506 YP_001288458.1 Mapped to H37Rv Rv2507 YP_001288459.1 Mapped to H37Rv Rv2508c YP_001288460.1 Mapped to H37Rv Rv2509 YP_001288461.1 Mapped to H37Rv Rv2510c YP_001288462.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001288463.1 Mapped to H37Rv Rv2512c YP_001288464.1 Mapped to H37Rv Rv2513 YP_001288465.1 Mapped to H37Rv Rv2514c YP_001288466.1 Mapped to H37Rv Rv2515c YP_001288467.1 Mapped to H37Rv Rv2516c YP_001288468.1 Mapped to H37Rv Rv2518c YP_001288469.1 Mapped to H37Rv Rv2519 YP_001288470.1 Mapped to H37Rv Rv2520c YP_001288471.1 Mapped to H37Rv Rv2521 YP_001288472.1 Mapped to H37Rv Rv2522c YP_001288473.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001288474.1 Mapped to H37Rv Rv2524c YP_001288475.1 Mapped to H37Rv Rv2525c YP_001288476.1 Mapped to H37Rv Rv2527 YP_001288477.1 Mapped to H37Rv Rv2528c YP_001288478.1 Mapped to H37Rv Rv2529 YP_001288479.1 Mapped to H37Rv Rv2530c YP_001288480.1 Mapped to H37Rv Rv2531c YP_001288481.1 Mapped to H37Rv Rv2532c YP_001288482.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001288483.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001288484.1 Mapped to H37Rv Rv2535c YP_001288485.1 Mapped to H37Rv Rv2536 YP_001288486.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001288487.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001288488.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001288489.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001288490.1 Mapped to H37Rv Rv2541 YP_001288491.1 Mapped to H37Rv Rv2542 YP_001288492.1 Mapped to H37Rv Rv2543 YP_001288493.1 Mapped to H37Rv Rv2544 YP_001288494.1 Mapped to H37Rv Rv2545 YP_001288495.1 Mapped to H37Rv Rv2546 YP_001288496.1 Mapped to H37Rv Rv2547 YP_001288497.1 Mapped to H37Rv Rv2548 YP_001288498.1 Mapped to H37Rv Rv2548 YP_001288499.1 Mapped to H37Rv Rv2549c YP_001288500.1 Mapped to H37Rv Rv2550c YP_001288501.1 Mapped to H37Rv Rv2551c YP_001288502.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001288503.1 Mapped to H37Rv Rv2553c YP_001288504.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001288505.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001288506.1 Mapped to H37Rv Rv2556c YP_001288507.1 Mapped to H37Rv Rv2557 YP_001288508.1 Mapped to H37Rv Rv2558 YP_001288509.1 Mapped to H37Rv Rv2559c YP_001288510.1 Mapped to H37Rv Rv2560 YP_001288511.1 Mapped to H37Rv Rv2560 YP_001288512.1 Mapped to H37Rv Rv2563 YP_001288513.1 Mapped to H37Rv Rv2564 YP_001288514.1 Mapped to H37Rv Rv2565 YP_001288515.1 Mapped to H37Rv Rv2566 YP_001288516.1 Mapped to H37Rv Rv2567 YP_001288517.1 Mapped to H37Rv Rv2568c YP_001288518.1 Mapped to H37Rv Rv2569c YP_001288519.1 Mapped to H37Rv Rv2570 YP_001288520.1 Mapped to H37Rv Rv2571c YP_001288521.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001288522.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001288523.1 Mapped to H37Rv Rv2574 YP_001288524.1 Mapped to H37Rv Rv2575 YP_001288525.1 Mapped to H37Rv Rv2576c YP_001288526.1 Mapped to H37Rv Rv2577 YP_001288527.1 Mapped to H37Rv Rv2578c YP_001288528.1 catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide YP_001288529.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001288530.1 Mapped to H37Rv Rv2581c YP_001288531.1 Mapped to H37Rv Rv2582 YP_001288532.1 Mapped to H37Rv Rv2583c YP_001288533.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001288534.1 Mapped to H37Rv Rv2585c YP_001288535.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001288536.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001288537.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001288538.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001288539.1 Mapped to H37Rv Rv2590 YP_001288540.1 Mapped to H37Rv Rv2591 YP_001288541.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001288542.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001288543.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001288544.1 Mapped to H37Rv Rv2596 YP_001288545.1 Mapped to H37Rv Rv2597 YP_001288546.1 Mapped to H37Rv Rv2598 YP_001288547.1 Mapped to H37Rv Rv2599 YP_001288548.1 Mapped to H37Rv Rv2600 YP_001288549.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001288550.1 Mapped to H37Rv Rv2602 YP_001288551.1 Mapped to H37Rv Rv2603c YP_001288552.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_001288553.1 Mapped to H37Rv Rv2605c YP_001288554.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001288555.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001288556.1 Mapped to H37Rv Rv2608 YP_001288557.1 Mapped to H37Rv Rv2609c YP_001288558.1 Mapped to H37Rv Rv2610c YP_001288559.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001288560.1 Mapped to H37Rv Rv2612c YP_001288561.1 Mapped to H37Rv Rv2613c YP_001288562.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001288563.1 Mapped to H37Rv Rv2615c YP_001288564.1 Mapped to H37Rv Rv2616 YP_001288565.1 Mapped to H37Rv Rv2617c YP_001288566.1 Mapped to H37Rv Rv2618 YP_001288567.1 Mapped to H37Rv Rv2619c YP_001288568.1 Mapped to H37Rv Rv2620c YP_001288569.1 Mapped to H37Rv Rv2621c YP_001288570.1 Mapped to H37Rv Rv2622 YP_001288571.1 Mapped to H37Rv Rv2623 YP_001288572.1 Mapped to H37Rv Rv2624c YP_001288573.1 Mapped to H37Rv Rv2625c YP_001288574.1 Mapped to H37Rv Rv2626c YP_001288575.1 Mapped to H37Rv Rv2627c YP_001288576.1 Mapped to H37Rv Rv2628 YP_001288577.1 Mapped to H37Rv Rv2629 YP_001288578.1 Mapped to H37Rv Rv2630 YP_001288579.1 Mapped to H37Rv Rv2631 YP_001288580.1 Mapped to H37Rv Rv2632c YP_001288581.1 Mapped to H37Rv Rv2633c YP_001288582.1 Mapped to H37Rv Rv2634c YP_001288583.1 Mapped to H37Rv Rv2636 YP_001288584.1 Mapped to H37Rv Rv2637 YP_001288585.1 Mapped to H37Rv Rv2638 YP_001288586.1 Mapped to H37Rv Rv2639c YP_001288587.1 Mapped to H37Rv Rv2640c YP_001288588.1 Mapped to H37Rv Rv2641 YP_001288589.1 Mapped to H37Rv Rv2642 YP_001288590.1 Mapped to H37Rv Rv2643 YP_001288591.1 Mapped to H37Rv Rv2643 YP_001288592.1 Mapped to H37Rv Rv2645 YP_001288593.1 Mapped to H37Rv Rv2646 YP_001288594.1 Mapped to H37Rv Rv2647 YP_001288595.1 Mapped to H37Rv Rv2650c YP_001288596.1 Mapped to H37Rv Rv2651c YP_001288597.1 Mapped to H37Rv Rv2652c YP_001288598.1 Mapped to H37Rv Rv2653c YP_001288599.1 Mapped to H37Rv Rv2654c YP_001288600.1 Mapped to H37Rv Rv2655c YP_001288601.1 Mapped to H37Rv Rv2656c YP_001288602.1 Mapped to H37Rv Rv2657c YP_001288603.1 Mapped to H37Rv Rv2658c YP_001288604.1 Mapped to H37Rv Rv2659c YP_001288605.1 Mapped to H37Rv Rv2660c YP_001288606.1 Mapped to H37Rv Rv2661c YP_001288607.1 Mapped to H37Rv Rv2663 YP_001288608.1 Mapped to H37Rv Rv2664 YP_001288609.1 Mapped to H37Rv Rv2665 YP_001288610.1 Mapped to H37Rv Rv2666 YP_001288611.1 Mapped to H37Rv Rv2667 YP_001288612.1 Mapped to H37Rv Rv2668 YP_001288613.1 Mapped to H37Rv Rv2669 YP_001288614.1 Mapped to H37Rv Rv2670c YP_001288615.1 Mapped to H37Rv Rv2671 YP_001288616.1 Mapped to H37Rv Rv2672 YP_001288617.1 Mapped to H37Rv Rv2673 YP_001288618.1 Mapped to H37Rv Rv2674 YP_001288619.1 Mapped to H37Rv Rv2675c YP_001288620.1 Mapped to H37Rv Rv2676c YP_001288621.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_001288622.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001288623.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001288624.1 Mapped to H37Rv Rv2680 YP_001288625.1 Mapped to H37Rv Rv2681 YP_001288626.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001288627.1 Mapped to H37Rv Rv2683 YP_001288628.1 Mapped to H37Rv Rv2684 YP_001288629.1 Mapped to H37Rv Rv2685 YP_001288630.1 Mapped to H37Rv Rv2686c YP_001288631.1 Mapped to H37Rv Rv2687c YP_001288632.1 Mapped to H37Rv Rv2688c YP_001288633.1 Mapped to H37Rv Rv2689c YP_001288634.1 Mapped to H37Rv Rv2690c YP_001288635.1 Mapped to H37Rv Rv2691 YP_001288636.1 Mapped to H37Rv Rv2692 YP_001288637.1 Mapped to H37Rv Rv2693c YP_001288638.1 Mapped to H37Rv Rv2694c YP_001288639.1 Mapped to H37Rv Rv2695 YP_001288640.1 Mapped to H37Rv Rv2696c YP_001288641.1 catalyzes the formation of dUMP from dUTP YP_001288642.1 Mapped to H37Rv Rv2698 YP_001288643.1 Mapped to H37Rv Rv2699c YP_001288644.1 Mapped to H37Rv Rv2700 YP_001288645.1 Mapped to H37Rv Rv2701c YP_001288646.1 Mapped to H37Rv Rv2702 YP_001288647.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released YP_001288648.1 Mapped to H37Rv Rv2704 YP_001288649.1 Mapped to H37Rv Rv2705c YP_001288650.1 Mapped to H37Rv Rv2707 YP_001288651.1 Mapped to H37Rv Rv2708c YP_001288652.1 Mapped to H37Rv Rv2709 YP_001288653.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase YP_001288654.1 Mapped to H37Rv Rv2711 YP_001288655.1 Mapped to H37Rv Rv2712c YP_001288656.1 catalyzes the conversion of NADPH to NADH YP_001288657.1 Mapped to H37Rv Rv2714 YP_001288658.1 Mapped to H37Rv Rv2715 YP_001288659.1 Mapped to H37Rv Rv2716 YP_001288660.1 Mapped to H37Rv Rv2717c YP_001288661.1 Mapped to H37Rv Rv2718c YP_001288662.1 Mapped to H37Rv Rv2719c YP_001288663.1 Represses a number of genes involved in the response to DNA damage YP_001288664.1 Mapped to H37Rv Rv2721c YP_001288665.1 Mapped to H37Rv Rv2723 YP_001288666.1 Mapped to H37Rv Rv2724c YP_001288667.1 Mapped to H37Rv Rv2725c YP_001288668.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001288669.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001288670.1 Mapped to H37Rv Rv2728c YP_001288671.1 Mapped to H37Rv Rv2729c YP_001288672.1 Mapped to H37Rv Rv2730 YP_001288673.1 Mapped to H37Rv Rv2731 YP_001288674.1 Mapped to H37Rv Rv2732c YP_001288675.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001288676.1 Mapped to H37Rv Rv2734 YP_001288677.1 Mapped to H37Rv Rv2735c YP_001288678.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001288679.1 these RecA proteins contain inteins; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001288680.1 Mapped to H37Rv Rv2737A YP_001288681.1 Mapped to H37Rv Rv2739c YP_001288682.1 Mapped to H37Rv Rv2740 YP_001288683.1 Mapped to H37Rv Rv2741 YP_001288684.1 Mapped to H37Rv Rv2742c YP_001288685.1 Mapped to H37Rv Rv2743c YP_001288686.1 Mapped to H37Rv Rv2744c YP_001288687.1 Mapped to H37Rv Rv2745c YP_001288688.1 Mapped to H37Rv Rv2746c YP_001288689.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis YP_001288690.1 Mapped to H37Rv Rv2748c YP_001288691.1 Mapped to H37Rv Rv2749 YP_001288692.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001288693.1 Mapped to H37Rv Rv2751 YP_001288694.1 Mapped to H37Rv Rv2752c YP_001288695.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001288696.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001288697.1 Mapped to H37Rv Rv2755c YP_001288698.1 Mapped to H37Rv Rv2756c YP_001288699.1 Mapped to H37Rv Rv2757c YP_001288700.1 Mapped to H37Rv Rv2758c YP_001288701.1 Mapped to H37Rv Rv2759c YP_001288702.1 Mapped to H37Rv Rv2760c YP_001288703.1 Mapped to H37Rv Rv2761c YP_001288704.1 Mapped to H37Rv Rv2762c YP_001288705.1 Mapped to H37Rv Rv2763c YP_001288706.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001288707.1 Mapped to H37Rv Rv2765 YP_001288708.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001288709.1 Mapped to H37Rv Rv2767c YP_001288710.1 Mapped to H37Rv Rv2768c YP_001288711.1 Mapped to H37Rv Rv2769c YP_001288712.1 Mapped to H37Rv Rv2770c YP_001288713.1 Mapped to H37Rv Rv2771c YP_001288714.1 Mapped to H37Rv Rv2772c YP_001288715.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001288716.1 Mapped to H37Rv Rv2774c YP_001288717.1 Mapped to H37Rv Rv2775 YP_001288718.1 Mapped to H37Rv Rv2776c YP_001288719.1 Mapped to H37Rv Rv2777c YP_001288720.1 Mapped to H37Rv Rv2778c YP_001288721.1 Mapped to H37Rv Rv2779c YP_001288722.1 Mapped to H37Rv Rv2780 YP_001288723.1 Mapped to H37Rv Rv2781c YP_001288724.1 Mapped to H37Rv Rv2782c YP_001288725.1 Mapped to H37Rv Rv2783c YP_001288726.1 Mapped to H37Rv Rv2784c YP_001288727.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001288728.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001288729.1 Mapped to H37Rv Rv2787 YP_001288730.1 Mapped to H37Rv Rv2788 YP_001288731.1 Mapped to H37Rv Rv2789c YP_001288732.1 Mapped to H37Rv Rv2790c YP_001288733.1 Mapped to H37Rv Rv2791c YP_001288734.1 Mapped to H37Rv Rv2792c YP_001288735.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001288736.1 Mapped to H37Rv Rv2794c YP_001288737.1 Mapped to H37Rv Rv2795c YP_001288738.1 Mapped to H37Rv Rv2796c YP_001288739.1 Mapped to H37Rv Rv2797c YP_001288740.1 Mapped to H37Rv Rv2798c YP_001288741.1 Mapped to H37Rv Rv2799 YP_001288742.1 Mapped to H37Rv Rv2800 YP_001288743.1 Mapped to H37Rv Rv2801c YP_001288745.1 Mapped to H37Rv Rv2802c YP_001288746.1 Mapped to H37Rv Rv2803 YP_001288748.1 Mapped to H37Rv Rv2805 YP_001288749.1 Mapped to H37Rv Rv2806 YP_001288750.1 Mapped to H37Rv Rv2807 YP_001288751.1 Mapped to H37Rv Rv2808 YP_001288752.1 Mapped to H37Rv Rv2809 YP_001288753.1 Mapped to H37Rv Rv2810c YP_001288754.1 Mapped to H37Rv Rv2811 YP_001288755.1 Mapped to H37Rv Rv2812 YP_001288756.1 Mapped to H37Rv Rv2813 YP_001288757.1 Mapped to H37Rv Rv2814c YP_001288758.1 Mapped to H37Rv Rv2815c YP_001288759.1 Mapped to H37Rv Rv2816c YP_001288760.1 Mapped to H37Rv Rv2817c YP_001288761.1 Mapped to H37Rv Rv2818c YP_001288762.1 Mapped to H37Rv Rv2819c YP_001288763.1 Mapped to H37Rv Rv2820c YP_001288764.1 Mapped to H37Rv Rv2821c YP_001288765.1 Mapped to H37Rv Rv2822c YP_001288766.1 Mapped to H37Rv Rv2823c YP_001288767.1 Mapped to H37Rv Rv2824c YP_001288768.1 Mapped to H37Rv Rv2825c YP_001288769.1 Mapped to H37Rv Rv2826c YP_001288770.1 Mapped to H37Rv Rv2827c YP_001288771.1 Mapped to H37Rv Rv2828c YP_001288772.1 Mapped to H37Rv Rv2828c YP_001288773.1 Mapped to H37Rv Rv2829c YP_001288774.1 Mapped to H37Rv Rv2830c YP_001288775.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001288776.1 Mapped to H37Rv Rv2832c YP_001288777.1 Mapped to H37Rv Rv2833c YP_001288778.1 Mapped to H37Rv Rv2834c YP_001288779.1 Mapped to H37Rv Rv2835c YP_001288780.1 Mapped to H37Rv Rv2836c YP_001288781.1 Mapped to H37Rv Rv2837c YP_001288782.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001288783.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001288784.1 Mapped to H37Rv Rv2840c YP_001288785.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001288786.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001288787.1 Mapped to H37Rv Rv2843 YP_001288788.1 Mapped to H37Rv Rv2844 YP_001288789.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001288790.1 Mapped to H37Rv Rv2846c YP_001288791.1 Mapped to H37Rv Rv2847c YP_001288792.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001288793.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001288794.1 Mapped to H37Rv Rv2850c YP_001288795.1 Mapped to H37Rv Rv2851c YP_001288796.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001288797.1 Mapped to H37Rv Rv2853 YP_001288798.1 Mapped to H37Rv Rv2854 YP_001288799.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide YP_001288800.1 Mapped to H37Rv Rv2856 YP_001288801.1 Mapped to H37Rv Rv2856 YP_001288802.1 Mapped to H37Rv Rv2857c YP_001288803.1 Mapped to H37Rv Rv2858c YP_001288804.1 Mapped to H37Rv Rv2859c YP_001288805.1 Mapped to H37Rv Rv2860c YP_001288806.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_001288807.1 Mapped to H37Rv Rv2862c YP_001288808.1 Mapped to H37Rv Rv2863 YP_001288809.1 Mapped to H37Rv Rv2864c YP_001288810.1 Mapped to H37Rv Rv2865 YP_001288811.1 Mapped to H37Rv Rv2866 YP_001288812.1 Mapped to H37Rv Rv2867c YP_001288813.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001288814.1 Mapped to H37Rv Rv2869c YP_001288815.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001288816.1 Mapped to H37Rv Rv2872 YP_001288817.1 Mapped to H37Rv Rv2873 YP_001288818.1 Mapped to H37Rv Rv2874 YP_001288819.1 Mapped to H37Rv Rv2875 YP_001288820.1 Mapped to H37Rv Rv2876 YP_001288821.1 Mapped to H37Rv Rv2877c YP_001288822.1 Mapped to H37Rv Rv2878c YP_001288823.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001288824.1 Mapped to H37Rv Rv2881c YP_001288825.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001288826.1 Catalyzes the phosphorylation of UMP to UDP YP_001288827.1 Mapped to H37Rv Rv2884 YP_001288828.1 Mapped to H37Rv Rv2885c YP_001288829.1 Mapped to H37Rv Rv2886c YP_001288830.1 Mapped to H37Rv Rv2887 YP_001288831.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001288832.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001288833.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001288834.1 Mapped to H37Rv Rv2891 YP_001288835.1 Mapped to H37Rv Rv2892c YP_001288836.1 Mapped to H37Rv Rv2893 YP_001288837.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001288838.1 Mapped to H37Rv Rv2895c YP_001288839.1 Mapped to H37Rv Rv2896c YP_001288840.1 Mapped to H37Rv Rv2897c YP_001288841.1 Mapped to H37Rv Rv2898c YP_001288842.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001288843.1 Mapped to H37Rv Rv2900c YP_001288844.1 Mapped to H37Rv Rv2901c YP_001288845.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001288846.1 Mapped to H37Rv Rv2903c YP_001288847.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001288848.1 Mapped to H37Rv Rv2905 YP_001288849.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001288850.1 Essential for efficient processing of 16S rRNA YP_001288851.1 Mapped to H37Rv Rv2908c YP_001288852.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001288853.1 Mapped to H37Rv Rv2910c YP_001288854.1 Mapped to H37Rv Rv2911 YP_001288855.1 Mapped to H37Rv Rv2912c YP_001288856.1 Mapped to H37Rv Rv2913c YP_001288857.1 Mapped to H37Rv Rv2914c YP_001288858.1 Mapped to H37Rv Rv2915c YP_001288859.1 Mapped to H37Rv Rv2916c YP_001288860.1 Mapped to H37Rv Rv2917 YP_001288861.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK YP_001288862.1 Mapped to H37Rv Rv2919c YP_001288863.1 Mapped to H37Rv Rv2920c YP_001288864.1 Mapped to H37Rv Rv2921c YP_001288865.1 Mapped to H37Rv Rv2922c YP_001288866.1 catalyzes the hydrolysis of acylphosphate YP_001288867.1 Mapped to H37Rv Rv2923c YP_001288868.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001288869.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001288870.1 Mapped to H37Rv Rv2926c YP_001288871.1 Mapped to H37Rv Rv2927c YP_001288872.1 Mapped to H37Rv Rv2928 YP_001288873.1 activates fatty acids by binding to coenzyme A YP_001288874.1 Mapped to H37Rv Rv2931 YP_001288875.1 Mapped to H37Rv Rv2932 YP_001288876.1 Mapped to H37Rv Rv2933 YP_001288877.1 Mapped to H37Rv Rv2934 YP_001288878.1 Mapped to H37Rv Rv2935 YP_001288879.1 Mapped to H37Rv Rv2936 YP_001288880.1 Mapped to H37Rv Rv2937 YP_001288881.1 Mapped to H37Rv Rv2938 YP_001288882.1 required for PDIM synthesis; phthiocerol and phthiodiolone dimycocerosate esters are scaffolds used for virulence-enhancing lipids; proposed to catalyze diesterification of phthiocerol and phthiodolone with mycocerosate; functions in polyketide synthesis YP_001288883.1 Mapped to H37Rv Rv2940c YP_001288884.1 activates fatty acids by binding to coenzyme A YP_001288885.1 Mapped to H37Rv Rv2942 YP_001288886.1 Mapped to H37Rv Rv2943 YP_001288887.1 Mapped to H37Rv Rv2944 YP_001288888.1 Mapped to H37Rv Rv2945c YP_001288889.1 Mapped to H37Rv Rv2946c YP_001288890.1 Mapped to H37Rv Rv2947c YP_001288891.1 activates fatty acids by binding to coenzyme A YP_001288892.1 Mapped to H37Rv Rv2949c YP_001288893.1 activates fatty acids by binding to coenzyme A YP_001288894.1 Mapped to H37Rv Rv2951c YP_001288895.1 Mapped to H37Rv Rv2952 YP_001288896.1 Mapped to H37Rv Rv2953 YP_001288897.1 Mapped to H37Rv Rv2954c YP_001288898.1 Mapped to H37Rv Rv2955c YP_001288899.1 Mapped to H37Rv Rv2956 YP_001288900.1 Mapped to H37Rv Rv2957 YP_001288901.1 Mapped to H37Rv Rv2958c YP_001288902.1 Mapped to H37Rv Rv2959c YP_001288903.1 Mapped to H37Rv Rv2960c YP_001288904.1 Mapped to H37Rv Rv2961 YP_001288905.1 Mapped to H37Rv Rv2962c YP_001288906.1 Mapped to H37Rv Rv2963 YP_001288907.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001288909.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001288910.1 Mapped to H37Rv Rv2966c YP_001288911.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001288912.1 Mapped to H37Rv Rv2968c YP_001288913.1 Mapped to H37Rv Rv2969c YP_001288914.1 Mapped to H37Rv Rv2970c YP_001288915.1 Mapped to H37Rv Rv2971 YP_001288916.1 Mapped to H37Rv Rv2972c YP_001288917.1 catalyzes branch migration in Holliday junction intermediates YP_001288918.1 Mapped to H37Rv Rv2974c YP_001288919.1 required for 70S ribosome assembly YP_001288920.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001288921.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001288922.1 Mapped to H37Rv Rv2978c YP_001288923.1 Mapped to H37Rv Rv2979c YP_001288924.1 Mapped to H37Rv Rv2980 YP_001288925.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001288926.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001288927.1 Mapped to H37Rv Rv2983 YP_001288928.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001288929.1 Mapped to H37Rv Rv2985 YP_001288930.1 Mapped to H37Rv Rv2986c YP_001288931.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001288932.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001288933.1 Mapped to H37Rv Rv2989 YP_001288934.1 Mapped to H37Rv Rv2990c YP_001288935.1 Mapped to H37Rv Rv2991 YP_001288936.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001288937.1 Mapped to H37Rv Rv2993c YP_001288938.1 Mapped to H37Rv Rv2994 YP_001288939.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001288940.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001288941.1 Mapped to H37Rv Rv2997 YP_001288942.1 Mapped to H37Rv Rv2998 YP_001288943.1 Mapped to H37Rv Rv2999 YP_001288944.1 Mapped to H37Rv Rv3000 YP_001288945.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001288946.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001288947.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_001288948.1 Mapped to H37Rv Rv3004 YP_001288949.1 Mapped to H37Rv Rv3005c YP_001288950.1 Mapped to H37Rv Rv3006 YP_001288951.1 Mapped to H37Rv Rv3007c YP_001288952.1 Mapped to H37Rv Rv3008 YP_001288953.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001288954.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001288955.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001288956.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001288957.1 Mapped to H37Rv Rv3013 YP_001288958.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001288959.1 Mapped to H37Rv Rv3015c YP_001288960.1 Mapped to H37Rv Rv3016 YP_001288961.1 Mapped to H37Rv Rv3017c YP_001288962.1 Mapped to H37Rv Rv3018c YP_001288963.1 Mapped to H37Rv Rv3018A YP_001288964.1 Mapped to H37Rv Rv3019c YP_001288965.1 Mapped to H37Rv Rv3020c YP_001288966.1 Mapped to H37Rv Rv3022c YP_001288967.1 Mapped to H37Rv Rv3022A YP_001288968.1 Mapped to H37Rv Rv3023c YP_001288969.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001288970.1 Mapped to H37Rv Rv3025c YP_001288971.1 Mapped to H37Rv Rv3026c YP_001288972.1 Mapped to H37Rv Rv3027c YP_001288973.1 Mapped to H37Rv Rv3028c YP_001288974.1 Mapped to H37Rv Rv3029c YP_001288975.1 Mapped to H37Rv Rv3030 YP_001288976.1 Mapped to H37Rv Rv3031 YP_001288977.1 Mapped to H37Rv Rv3032 YP_001288978.1 Mapped to H37Rv Rv3033 YP_001288979.1 Mapped to H37Rv Rv3034c YP_001288980.1 Mapped to H37Rv Rv3035 YP_001288981.1 Mapped to H37Rv Rv3036c YP_001288982.1 Mapped to H37Rv Rv3037c YP_001288983.1 Mapped to H37Rv Rv3038c YP_001288984.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001288985.1 Mapped to H37Rv Rv3040c YP_001288986.1 Mapped to H37Rv Rv3041c YP_001288987.1 Mapped to H37Rv Rv3042c YP_001288988.1 Mapped to H37Rv Rv3043c YP_001288989.1 Mapped to H37Rv Rv3044 YP_001288990.1 Mapped to H37Rv Rv3045 YP_001288991.1 Mapped to H37Rv Rv3046c YP_001288992.1 Mapped to H37Rv Rv3047c YP_001288993.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001288994.1 Mapped to H37Rv Rv3049c YP_001288995.1 Mapped to H37Rv Rv3050c YP_001288996.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001288997.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001288998.1 Mapped to H37Rv Rv3053c YP_001289000.1 Mapped to H37Rv Rv3054c YP_001289001.1 Mapped to H37Rv Rv3055 YP_001289002.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001289003.1 Mapped to H37Rv Rv3057c YP_001289004.1 Mapped to H37Rv Rv3058c YP_001289005.1 Mapped to H37Rv Rv3059 YP_001289006.1 Mapped to H37Rv Rv3060c YP_001289007.1 Mapped to H37Rv Rv3061c YP_001289008.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001289009.1 Mapped to H37Rv Rv3063 YP_001289010.1 Mapped to H37Rv Rv3064c YP_001289011.1 Mapped to H37Rv Rv3065 YP_001289012.1 Mapped to H37Rv Rv3066 YP_001289013.1 Mapped to H37Rv Rv3067 YP_001289014.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001289015.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001289016.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001289017.1 Mapped to H37Rv Rv3071 YP_001289018.1 Mapped to H37Rv Rv3072c YP_001289019.1 Mapped to H37Rv Rv3073c YP_001289020.1 Mapped to H37Rv Rv3074 YP_001289021.1 Mapped to H37Rv Rv3075c YP_001289022.1 Mapped to H37Rv Rv3076 YP_001289023.1 Mapped to H37Rv Rv3077 YP_001289024.1 Mapped to H37Rv Rv3078 YP_001289025.1 Mapped to H37Rv Rv3079c YP_001289026.1 Mapped to H37Rv Rv3080c YP_001289027.1 Mapped to H37Rv Rv3081 YP_001289028.1 Mapped to H37Rv Rv3082c YP_001289029.1 Mapped to H37Rv Rv3083 YP_001289030.1 Mapped to H37Rv Rv3084 YP_001289031.1 Mapped to H37Rv Rv3085 YP_001289032.1 Mapped to H37Rv Rv3086 YP_001289033.1 Mapped to H37Rv Rv3087 YP_001289034.1 Mapped to H37Rv Rv3088 YP_001289035.1 Mapped to H37Rv Rv3089 YP_001289036.1 Mapped to H37Rv Rv3090 YP_001289037.1 Mapped to H37Rv Rv3091 YP_001289038.1 Mapped to H37Rv Rv3092c YP_001289039.1 Mapped to H37Rv Rv3093c YP_001289040.1 Mapped to H37Rv Rv3094c YP_001289041.1 Mapped to H37Rv Rv3095 YP_001289042.1 Mapped to H37Rv Rv3096 YP_001289043.1 Mapped to H37Rv Rv3097c YP_001289044.1 Mapped to H37Rv Rv3098c YP_001289045.1 Mapped to H37Rv Rv3099c YP_001289046.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001289047.1 Mapped to H37Rv Rv3101c YP_001289048.1 Mapped to H37Rv Rv3102c YP_001289049.1 Mapped to H37Rv Rv3103c YP_001289050.1 Mapped to H37Rv Rv3104c YP_001289051.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001289052.1 Mapped to H37Rv Rv3106 YP_001289053.1 Mapped to H37Rv Rv3107c YP_001289054.1 Mapped to H37Rv Rv3108 YP_001289055.1 Mapped to H37Rv Rv3109 YP_001289056.1 Mapped to H37Rv Rv3110 YP_001289057.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001289058.1 Mapped to H37Rv Rv3112 YP_001289061.1 Mapped to H37Rv Rv3114 YP_001289062.1 Mapped to H37Rv Rv3115 YP_001289063.1 Mapped to H37Rv Rv3116 YP_001289064.1 Mapped to H37Rv Rv3117 YP_001289065.1 Mapped to H37Rv Rv3118 YP_001289066.1 Mapped to H37Rv Rv3119 YP_001289067.1 Mapped to H37Rv Rv3120 YP_001289068.1 Mapped to H37Rv Rv3121 YP_001289069.1 Mapped to H37Rv Rv3122 YP_001289070.1 Mapped to H37Rv Rv3123 YP_001289071.1 Mapped to H37Rv Rv3124 YP_001289072.1 Mapped to H37Rv Rv3125c YP_001289073.1 Mapped to H37Rv Rv3126c YP_001289074.1 Mapped to H37Rv Rv3127 YP_001289075.1 Mapped to H37Rv Rv3128c YP_001289076.1 Mapped to H37Rv Rv3128c YP_001289077.1 Mapped to H37Rv Rv3129 YP_001289078.1 Mapped to H37Rv Rv3130c YP_001289079.1 Mapped to H37Rv Rv3131 YP_001289080.1 Mapped to H37Rv Rv3132c YP_001289081.1 Mapped to H37Rv Rv3133c YP_001289082.1 Mapped to H37Rv Rv3134c YP_001289083.1 Mapped to H37Rv Rv3135 YP_001289084.1 Mapped to H37Rv Rv3136 YP_001289085.1 Mapped to H37Rv Rv3137 YP_001289086.1 Mapped to H37Rv Rv3138 YP_001289087.1 Mapped to H37Rv Rv3139 YP_001289088.1 Mapped to H37Rv Rv3140 YP_001289089.1 Mapped to H37Rv Rv3141 YP_001289090.1 Mapped to H37Rv Rv3142c YP_001289091.1 Mapped to H37Rv Rv3143 YP_001289092.1 Mapped to H37Rv Rv3144c YP_001289093.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289094.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001289095.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289096.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289097.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289098.1 Mapped to H37Rv Rv3150 YP_001289099.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289100.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289101.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289102.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289103.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289104.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001289105.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289106.1 Catalyzes the transfer of electrons from NADH to quinone YP_001289107.1 Mapped to H37Rv Rv3159c YP_001289108.1 Mapped to H37Rv Rv3160c YP_001289109.1 Mapped to H37Rv Rv3161c YP_001289110.1 Mapped to H37Rv Rv3162c YP_001289111.1 Mapped to H37Rv Rv3163c YP_001289112.1 Mapped to H37Rv Rv3164c YP_001289113.1 Mapped to H37Rv Rv3165c YP_001289114.1 Mapped to H37Rv Rv3166c YP_001289115.1 Mapped to H37Rv Rv3167c YP_001289116.1 Mapped to H37Rv Rv3168 YP_001289117.1 Mapped to H37Rv Rv3169 YP_001289118.1 Mapped to H37Rv Rv3170 YP_001289119.1 Mapped to H37Rv Rv3171c YP_001289120.1 Mapped to H37Rv Rv3172c YP_001289121.1 Mapped to H37Rv Rv3173c YP_001289122.1 Mapped to H37Rv Rv3174 YP_001289123.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001289124.1 Mapped to H37Rv Rv3176c YP_001289125.1 Mapped to H37Rv Rv3177 YP_001289126.1 Mapped to H37Rv Rv3178 YP_001289128.1 Mapped to H37Rv Rv3179 YP_001289129.1 Mapped to H37Rv Rv3180c YP_001289130.1 Mapped to H37Rv Rv3181c YP_001289131.1 Mapped to H37Rv Rv3182 YP_001289132.1 Mapped to H37Rv Rv3183 YP_001289133.1 Mapped to H37Rv Rv3183 YP_001289135.1 Mapped to H37Rv Rv3188 YP_001289136.1 Mapped to H37Rv Rv3189 YP_001289137.1 Mapped to H37Rv Rv3190c YP_001289138.1 Mapped to H37Rv Rv3191c YP_001289139.1 Mapped to H37Rv Rv3192 YP_001289140.1 Mapped to H37Rv Rv3193c YP_001289141.1 Mapped to H37Rv Rv3194c YP_001289142.1 Mapped to H37Rv Rv3195 YP_001289143.1 Mapped to H37Rv Rv3196 YP_001289144.1 Mapped to H37Rv Rv3196A YP_001289145.1 Mapped to H37Rv Rv3197 YP_001289146.1 Mapped to H37Rv Rv3197A YP_001289147.1 Mapped to H37Rv Rv3198c YP_001289148.1 Mapped to H37Rv Rv3198A YP_001289149.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001289150.1 Mapped to H37Rv Rv3200c YP_001289151.1 Mapped to H37Rv Rv3201c YP_001289152.1 Mapped to H37Rv Rv3202c YP_001289153.1 Mapped to H37Rv Rv3202c YP_001289154.1 Mapped to H37Rv Rv3203 YP_001289155.1 Mapped to H37Rv Rv3204 YP_001289156.1 Mapped to H37Rv Rv3205c YP_001289157.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation YP_001289158.1 Mapped to H37Rv Rv3207c YP_001289159.1 Mapped to H37Rv Rv3208 YP_001289160.1 Mapped to H37Rv Rv3208A YP_001289162.1 Mapped to H37Rv Rv3209 YP_001289163.1 Mapped to H37Rv Rv3210c YP_001289164.1 Mapped to H37Rv Rv3211 YP_001289165.1 Mapped to H37Rv Rv3212 YP_001289166.1 Mapped to H37Rv Rv3213c YP_001289167.1 forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily YP_001289168.1 Mapped to H37Rv Rv3215 YP_001289169.1 Mapped to H37Rv Rv3216 YP_001289170.1 Mapped to H37Rv Rv3217c YP_001289171.1 Mapped to H37Rv Rv3218 YP_001289172.1 Mapped to H37Rv Rv3219 YP_001289173.1 Mapped to H37Rv Rv3220c YP_001289174.1 Mapped to H37Rv Rv3221c YP_001289175.1 Mapped to H37Rv Rv3221A YP_001289176.1 Mapped to H37Rv Rv3222c YP_001289177.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001289178.1 Mapped to H37Rv Rv3224 YP_001289179.1 Mapped to H37Rv Rv3224A YP_001289180.1 Mapped to H37Rv Rv3224B YP_001289181.1 Mapped to H37Rv Rv3225c YP_001289182.1 Mapped to H37Rv Rv3226c YP_001289183.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001289184.1 Mapped to H37Rv Rv3228 YP_001289185.1 Mapped to H37Rv Rv3229c YP_001289186.1 Mapped to H37Rv Rv3230c YP_001289187.1 Mapped to H37Rv Rv3231c YP_001289188.1 Mapped to H37Rv Rv3232c YP_001289189.1 Mapped to H37Rv Rv3233c YP_001289190.1 Mapped to H37Rv Rv3234c YP_001289191.1 Mapped to H37Rv Rv3235 YP_001289192.1 Mapped to H37Rv Rv3236c YP_001289193.1 Mapped to H37Rv Rv3237c YP_001289194.1 Mapped to H37Rv Rv3238c YP_001289195.1 Mapped to H37Rv Rv3239c YP_001289196.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001289197.1 Mapped to H37Rv Rv3241c YP_001289198.1 Mapped to H37Rv Rv3242c YP_001289199.1 Mapped to H37Rv Rv3243c YP_001289200.1 Mapped to H37Rv Rv3244c YP_001289201.1 Mapped to H37Rv Rv3245c YP_001289202.1 Mapped to H37Rv Rv3246c YP_001289203.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001289204.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001289205.1 Mapped to H37Rv Rv3249c YP_001289206.1 Mapped to H37Rv Rv3250c YP_001289207.1 Mapped to H37Rv Rv3251c YP_001289208.1 Mapped to H37Rv Rv3252c YP_001289209.1 Mapped to H37Rv Rv3253c YP_001289210.1 Mapped to H37Rv Rv3254 YP_001289211.1 Mapped to H37Rv Rv3255c YP_001289212.1 Mapped to H37Rv Rv3256c YP_001289213.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells YP_001289214.1 Mapped to H37Rv Rv3258c YP_001289215.1 Mapped to H37Rv Rv3259 YP_001289216.1 Mapped to H37Rv Rv3260c YP_001289217.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) YP_001289218.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0) YP_001289219.1 Mapped to H37Rv Rv3263 YP_001289220.1 Mapped to H37Rv Rv3264c YP_001289221.1 Mapped to H37Rv Rv3265c YP_001289222.1 Mapped to H37Rv Rv3266c YP_001289223.1 Mapped to H37Rv Rv3267 YP_001289224.1 Mapped to H37Rv Rv3268 YP_001289225.1 Mapped to H37Rv Rv3269 YP_001289226.1 Mapped to H37Rv Rv3270 YP_001289227.1 Mapped to H37Rv Rv3271c YP_001289228.1 Mapped to H37Rv Rv3272 YP_001289229.1 Mapped to H37Rv Rv3273 YP_001289230.1 Mapped to H37Rv Rv3274c YP_001289231.1 Mapped to H37Rv Rv3275c YP_001289232.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001289233.1 Mapped to H37Rv Rv3277 YP_001289234.1 Mapped to H37Rv Rv3278c YP_001289235.1 Mapped to H37Rv Rv3279c YP_001289236.1 Mapped to H37Rv Rv3280 YP_001289237.1 Mapped to H37Rv Rv3281 YP_001289238.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001289239.1 Mapped to H37Rv Rv3283 YP_001289240.1 Mapped to H37Rv Rv3284 YP_001289241.1 Mapped to H37Rv Rv3285 YP_001289242.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock YP_001289243.1 Mapped to H37Rv Rv3287c YP_001289244.1 Mapped to H37Rv Rv3288c YP_001289245.1 Mapped to H37Rv Rv3289c YP_001289246.1 catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate YP_001289247.1 Mapped to H37Rv Rv3291c YP_001289248.1 Mapped to H37Rv Rv3292 YP_001289249.1 Mapped to H37Rv Rv3293 YP_001289250.1 Mapped to H37Rv Rv3294c YP_001289251.1 Mapped to H37Rv Rv3295 YP_001289252.1 Mapped to H37Rv Rv3296 YP_001289253.1 Mapped to H37Rv Rv3297 YP_001289254.1 Mapped to H37Rv Rv3298c YP_001289255.1 Mapped to H37Rv Rv3299c YP_001289256.1 Mapped to H37Rv Rv3300c YP_001289257.1 Mapped to H37Rv Rv3301c YP_001289258.1 Mapped to H37Rv Rv3302c YP_001289259.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity YP_001289260.1 Mapped to H37Rv Rv3304 YP_001289261.1 Mapped to H37Rv Rv3305c YP_001289262.1 Mapped to H37Rv Rv3306c YP_001289263.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001289264.1 Mapped to H37Rv Rv3308 YP_001289265.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001289266.1 Mapped to H37Rv Rv3310 YP_001289267.1 Mapped to H37Rv Rv3311 YP_001289268.1 Mapped to H37Rv Rv3312c YP_001289269.1 Mapped to H37Rv Rv3312c YP_001289270.1 Mapped to H37Rv Rv3312A YP_001289271.1 catalyzes the formation of inosine from adenosine YP_001289272.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001289273.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001289274.1 Mapped to H37Rv Rv3316 YP_001289275.1 Mapped to H37Rv Rv3317 YP_001289276.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001289277.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001289278.1 Mapped to H37Rv Rv3320c YP_001289279.1 Mapped to H37Rv Rv3321c YP_001289280.1 Mapped to H37Rv Rv3322c YP_001289281.1 Mapped to H37Rv Rv3323c YP_001289282.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001289283.1 Mapped to H37Rv Rv3324A YP_001289284.1 Mapped to H37Rv Rv3324A YP_001289286.1 Mapped to H37Rv Rv3327 YP_001289287.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001289288.1 Mapped to H37Rv Rv3329 YP_001289289.1 Mapped to H37Rv Rv3330 YP_001289290.1 Mapped to H37Rv Rv3331 YP_001289291.1 Mapped to H37Rv Rv3332 YP_001289292.1 Mapped to H37Rv Rv3333c YP_001289294.1 Mapped to H37Rv Rv3334 YP_001289295.1 Mapped to H37Rv Rv3335c YP_001289296.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001289297.1 Mapped to H37Rv Rv3337 YP_001289298.1 Converts isocitrate to alpha ketoglutarate YP_001289300.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_001289301.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001289302.1 Mapped to H37Rv Rv3342 YP_001289303.1 Mapped to H37Rv Rv3343c YP_001289304.1 Mapped to H37Rv Rv3344c YP_001289305.1 Mapped to H37Rv Rv3345c YP_001289306.1 Mapped to H37Rv Rv3346c YP_001289307.1 Mapped to H37Rv Rv3347c YP_001289308.1 Mapped to H37Rv Rv3347c YP_001289310.1 Mapped to H37Rv Rv3348 YP_001289311.1 Mapped to H37Rv Rv3349c YP_001289313.1 Mapped to H37Rv Rv3350c YP_001289314.1 Mapped to H37Rv Rv3351c YP_001289315.1 Mapped to H37Rv Rv3352c YP_001289316.1 Mapped to H37Rv Rv3353c YP_001289317.1 Mapped to H37Rv Rv3354 YP_001289318.1 Mapped to H37Rv Rv3355c YP_001289319.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001289320.1 Mapped to H37Rv Rv3357 YP_001289321.1 Mapped to H37Rv Rv3358 YP_001289322.1 Mapped to H37Rv Rv3359 YP_001289323.1 Mapped to H37Rv Rv3360 YP_001289324.1 Mapped to H37Rv Rv3361c YP_001289325.1 Mapped to H37Rv Rv3362c YP_001289326.1 Mapped to H37Rv Rv3363c YP_001289327.1 Mapped to H37Rv Rv3364c YP_001289328.1 Mapped to H37Rv Rv3365c YP_001289329.1 Mapped to H37Rv Rv3366 YP_001289330.1 Mapped to H37Rv Rv3367 YP_001289331.1 Mapped to H37Rv Rv3368c YP_001289332.1 Mapped to H37Rv Rv3369 YP_001289333.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_001289334.1 Mapped to H37Rv Rv3371 YP_001289335.1 Mapped to H37Rv Rv3372 YP_001289336.1 Mapped to H37Rv Rv3373 YP_001289337.1 Mapped to H37Rv Rv3374 YP_001289338.1 Mapped to H37Rv Rv3375 YP_001289339.1 Mapped to H37Rv Rv3376 YP_001289340.1 Mapped to H37Rv Rv3377c YP_001289341.1 Mapped to H37Rv Rv3378c YP_001289342.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001289343.1 Mapped to H37Rv Rv3382c YP_001289344.1 Mapped to H37Rv Rv3383c YP_001289345.1 Mapped to H37Rv Rv3384c YP_001289346.1 Mapped to H37Rv Rv3385c YP_001289347.1 Mapped to H37Rv Rv3386 YP_001289348.1 Mapped to H37Rv Rv3387 YP_001289349.1 Mapped to H37Rv Rv3388 YP_001289350.1 Mapped to H37Rv Rv3389c YP_001289351.1 Mapped to H37Rv Rv3390 YP_001289352.1 Mapped to H37Rv Rv3391 YP_001289353.1 Mapped to H37Rv Rv3392c YP_001289354.1 Mapped to H37Rv Rv3393 YP_001289355.1 Mapped to H37Rv Rv3394c YP_001289356.1 Mapped to H37Rv Rv3395c YP_001289357.1 Mapped to H37Rv Rv3395A YP_001289358.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001289359.1 Mapped to H37Rv Rv3397c YP_001289360.1 Mapped to H37Rv Rv3398c YP_001289361.1 Mapped to H37Rv Rv3399 YP_001289362.1 Mapped to H37Rv Rv3400 YP_001289363.1 Mapped to H37Rv Rv3401 YP_001289364.1 Mapped to H37Rv Rv3402c YP_001289365.1 Mapped to H37Rv Rv3403c YP_001289366.1 Mapped to H37Rv Rv3404c YP_001289367.1 Mapped to H37Rv Rv3405c YP_001289368.1 Mapped to H37Rv Rv3406 YP_001289369.1 Mapped to H37Rv Rv3408 YP_001289370.1 Mapped to H37Rv Rv3409c YP_001289371.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001289372.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001289373.1 Mapped to H37Rv Rv3412 YP_001289374.1 Mapped to H37Rv Rv3413c YP_001289375.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase YP_001289376.1 Mapped to H37Rv Rv3415c YP_001289377.1 Mapped to H37Rv Rv3416 YP_001289378.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001289379.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001289380.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001289381.1 Mapped to H37Rv Rv3420c YP_001289382.1 Mapped to H37Rv Rv3421c YP_001289383.1 Mapped to H37Rv Rv3422c YP_001289384.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001289385.1 Mapped to H37Rv Rv3423c YP_001289386.1 Mapped to H37Rv Rv3423c YP_001289387.1 Mapped to H37Rv Rv3423c YP_001289389.1 Mapped to H37Rv Rv3425 YP_001289390.1 Mapped to H37Rv Rv3425 YP_001289391.1 Mapped to H37Rv Rv3428c YP_001289392.1 Mapped to H37Rv Rv3429 YP_001289393.1 Mapped to H37Rv Rv3430c YP_001289395.1 Mapped to H37Rv Rv3431c YP_001289396.1 Mapped to H37Rv Rv3432c YP_001289397.1 Mapped to H37Rv Rv3433c YP_001289398.1 Mapped to H37Rv Rv3434c YP_001289399.1 Mapped to H37Rv Rv3435c YP_001289400.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001289401.1 Mapped to H37Rv Rv3437 YP_001289402.1 Mapped to H37Rv Rv3438 YP_001289403.1 Mapped to H37Rv Rv3439c YP_001289404.1 Mapped to H37Rv Rv3440c YP_001289405.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001289406.1 forms a direct contact with the tRNA during translation YP_001289407.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001289408.1 Mapped to H37Rv Rv3444c YP_001289409.1 Mapped to H37Rv Rv3445c YP_001289410.1 Mapped to H37Rv Rv3446c YP_001289411.1 Mapped to H37Rv Rv3447c YP_001289412.1 Mapped to H37Rv Rv3448 YP_001289413.1 Mapped to H37Rv Rv3449 YP_001289414.1 Mapped to H37Rv Rv3450c YP_001289415.1 Mapped to H37Rv Rv3451 YP_001289416.1 Mapped to H37Rv Rv3452 YP_001289417.1 Mapped to H37Rv Rv3453 YP_001289418.1 Mapped to H37Rv Rv3454 YP_001289419.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001289420.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001289421.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001289422.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001289423.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001289424.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001289425.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001289426.1 Mapped to H37Rv Rv3462c YP_001289427.1 Mapped to H37Rv Rv3463 YP_001289428.1 Mapped to H37Rv Rv3464 YP_001289429.1 Mapped to H37Rv Rv3465 YP_001289430.1 Mapped to H37Rv Rv3466 YP_001289431.1 Mapped to H37Rv Rv3467 YP_001289432.1 Mapped to H37Rv Rv3468c YP_001289433.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001289434.1 Mapped to H37Rv Rv3470c YP_001289435.1 Mapped to H37Rv Rv3471c YP_001289436.1 Mapped to H37Rv Rv3472 YP_001289437.1 Mapped to H37Rv Rv3473c YP_001289438.1 Mapped to H37Rv Rv3476c YP_001289439.1 Mapped to H37Rv Rv3477 YP_001289440.1 Mapped to H37Rv Rv3478 YP_001289441.1 Mapped to H37Rv Rv3479 YP_001289442.1 Mapped to H37Rv Rv3480c YP_001289443.1 Mapped to H37Rv Rv3481c YP_001289444.1 Mapped to H37Rv Rv3482c YP_001289445.1 Mapped to H37Rv Rv3483c YP_001289446.1 Mapped to H37Rv Rv3484 YP_001289447.1 Mapped to H37Rv Rv3485c YP_001289448.1 Mapped to H37Rv Rv3486 YP_001289449.1 Mapped to H37Rv Rv3487c YP_001289450.1 Mapped to H37Rv Rv3488 YP_001289451.1 Mapped to H37Rv Rv3490 YP_001289452.1 Mapped to H37Rv Rv3491 YP_001289453.1 Mapped to H37Rv Rv3492c YP_001289454.1 Mapped to H37Rv Rv3493c YP_001289455.1 Mapped to H37Rv Rv3494c YP_001289456.1 Mapped to H37Rv Rv3495c YP_001289457.1 Mapped to H37Rv Rv3496c YP_001289458.1 Mapped to H37Rv Rv3497c YP_001289459.1 Mapped to H37Rv Rv3498c YP_001289460.1 Mapped to H37Rv Rv3499c YP_001289461.1 Mapped to H37Rv Rv3500c YP_001289462.1 Mapped to H37Rv Rv3501c YP_001289463.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001289464.1 Mapped to H37Rv Rv3503c YP_001289465.1 Mapped to H37Rv Rv3504 YP_001289466.1 Mapped to H37Rv Rv3505 YP_001289467.1 activates fatty acids by binding to coenzyme A YP_001289468.1 Mapped to H37Rv Rv3507 YP_001289469.1 Mapped to H37Rv Rv3508 YP_001289470.1 thiamine-pyrophosphate requiring enzyme YP_001289471.1 Mapped to H37Rv Rv3510c YP_001289472.1 Mapped to H37Rv Rv3510c YP_001289473.1 Mapped to H37Rv Rv3513c YP_001289474.1 Mapped to H37Rv Rv3514 YP_001289475.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence YP_001289476.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001289477.1 Mapped to H37Rv Rv3517 YP_001289478.1 Mapped to H37Rv Rv3518c YP_001289479.1 Mapped to H37Rv Rv3519 YP_001289480.1 Mapped to H37Rv Rv3520c YP_001289481.1 Mapped to H37Rv Rv3521 YP_001289482.1 Mapped to H37Rv Rv3522 YP_001289483.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001289484.1 Mapped to H37Rv Rv3524 YP_001289485.1 Mapped to H37Rv Rv3525c YP_001289486.1 Mapped to H37Rv Rv3526 YP_001289487.1 Mapped to H37Rv Rv3527 YP_001289488.1 Mapped to H37Rv Rv3528c YP_001289489.1 Mapped to H37Rv Rv3529c YP_001289490.1 Mapped to H37Rv Rv3530c YP_001289491.1 Mapped to H37Rv Rv3531c YP_001289492.1 Mapped to H37Rv Rv3532 YP_001289493.1 Mapped to H37Rv Rv3533c YP_001289494.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001289495.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001289496.1 Mapped to H37Rv Rv3536c YP_001289497.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione YP_001289498.1 Mapped to H37Rv Rv3538 YP_001289499.1 Mapped to H37Rv Rv3539 YP_001289500.1 Mapped to H37Rv Rv3540c YP_001289501.1 Mapped to H37Rv Rv3541c YP_001289502.1 Mapped to H37Rv Rv3542c YP_001289503.1 Mapped to H37Rv Rv3543c YP_001289504.1 Mapped to H37Rv Rv3544c YP_001289505.1 Mapped to H37Rv Rv3545c YP_001289506.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001289507.1 Mapped to H37Rv Rv3547 YP_001289508.1 Mapped to H37Rv Rv3548c YP_001289509.1 Mapped to H37Rv Rv3549c YP_001289510.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001289511.1 Mapped to H37Rv Rv3551 YP_001289512.1 Mapped to H37Rv Rv3552 YP_001289513.1 Mapped to H37Rv Rv3553 YP_001289514.1 Mapped to H37Rv Rv3554 YP_001289515.1 Mapped to H37Rv Rv3555c YP_001289516.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001289517.1 Mapped to H37Rv Rv3557c YP_001289518.1 Mapped to H37Rv Rv3558 YP_001289519.1 Mapped to H37Rv Rv3559c YP_001289520.1 Mapped to H37Rv Rv3560c YP_001289521.1 activates fatty acids by binding to coenzyme A YP_001289522.1 Mapped to H37Rv Rv3562 YP_001289523.1 Mapped to H37Rv Rv3563 YP_001289524.1 Mapped to H37Rv Rv3564 YP_001289525.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001289526.1 Mapped to H37Rv Rv3565 YP_001289527.1 Mapped to H37Rv Rv3567c YP_001289528.1 Mapped to H37Rv Rv3568c YP_001289529.1 Mapped to H37Rv Rv3569c YP_001289530.1 Mapped to H37Rv Rv3570c YP_001289531.1 Mapped to H37Rv Rv3571 YP_001289532.1 Mapped to H37Rv Rv3572 YP_001289533.1 Mapped to H37Rv Rv3573c YP_001289534.1 Mapped to H37Rv Rv3574 YP_001289535.1 Mapped to H37Rv Rv3575c YP_001289536.1 Mapped to H37Rv Rv3576 YP_001289537.1 Mapped to H37Rv Rv3577 YP_001289538.1 Mapped to H37Rv Rv3578 YP_001289539.1 Mapped to H37Rv Rv3579c YP_001289540.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001289541.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001289542.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001289543.1 Mapped to H37Rv Rv3583c YP_001289544.1 Mapped to H37Rv Rv3584 YP_001289545.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001289546.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair YP_001289547.1 Mapped to H37Rv Rv3587c YP_001289548.1 Mapped to H37Rv Rv3588c YP_001289549.1 Mapped to H37Rv Rv3589 YP_001289550.1 Mapped to H37Rv Rv3590c YP_001289551.1 Mapped to H37Rv Rv3591c YP_001289552.1 Mapped to H37Rv Rv3592 YP_001289553.1 Mapped to H37Rv Rv3593 YP_001289554.1 Mapped to H37Rv Rv3594 YP_001289555.1 Mapped to H37Rv Rv3595c YP_001289556.1 Mapped to H37Rv Rv3596c YP_001289557.1 Mapped to H37Rv Rv3597c YP_001289558.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001289559.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001289560.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001289561.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001289562.1 Mapped to H37Rv Rv3603c YP_001289563.1 Mapped to H37Rv Rv3604c YP_001289564.1 Mapped to H37Rv Rv3605c YP_001289565.1 Mapped to H37Rv Rv3606c YP_001289566.1 Mapped to H37Rv Rv3607c YP_001289567.1 Mapped to H37Rv Rv3608c YP_001289568.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001289569.1 Mapped to H37Rv Rv3610c YP_001289570.1 Mapped to H37Rv Rv3611 YP_001289571.1 Mapped to H37Rv Rv3612c YP_001289572.1 Mapped to H37Rv Rv3614c YP_001289573.1 Mapped to H37Rv Rv3615c YP_001289574.1 Mapped to H37Rv Rv3616c YP_001289575.1 Mapped to H37Rv Rv3617 YP_001289576.1 Mapped to H37Rv Rv3618 YP_001289577.1 Mapped to H37Rv Rv3619c YP_001289578.1 Mapped to H37Rv Rv3620c YP_001289579.1 Mapped to H37Rv Rv3621c YP_001289580.1 Mapped to H37Rv Rv3622c YP_001289581.1 Mapped to H37Rv Rv3623 YP_001289582.1 Mapped to H37Rv Rv3624c YP_001289583.1 Mapped to H37Rv Rv3625c YP_001289584.1 Mapped to H37Rv Rv3626c YP_001289585.1 Mapped to H37Rv Rv3627c YP_001289586.1 Mapped to H37Rv Rv3628 YP_001289587.1 Mapped to H37Rv Rv3629c YP_001289588.1 Mapped to H37Rv Rv3630 YP_001289589.1 Mapped to H37Rv Rv3631 YP_001289590.1 Mapped to H37Rv Rv3632 YP_001289591.1 Mapped to H37Rv Rv3633 YP_001289592.1 Mapped to H37Rv Rv3634c YP_001289593.1 Mapped to H37Rv Rv3635 YP_001289594.1 Mapped to H37Rv Rv3636 YP_001289595.1 Mapped to H37Rv Rv3637 YP_001289596.1 Mapped to H37Rv Rv3638 YP_001289597.1 Mapped to H37Rv Rv3639c YP_001289598.1 Mapped to H37Rv Rv3640c YP_001289599.1 Mapped to H37Rv Rv3641c YP_001289600.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001289601.1 Mapped to H37Rv Rv3645 YP_001289602.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001289603.1 Mapped to H37Rv Rv3647c YP_001289604.1 Mapped to H37Rv Rv3648c YP_001289605.1 Mapped to H37Rv Rv3649 YP_001289606.1 Mapped to H37Rv Rv3650 YP_001289607.1 Mapped to H37Rv Rv3651 YP_001289608.1 Mapped to H37Rv Rv3652 YP_001289609.1 Mapped to H37Rv Rv3652 YP_001289610.1 Mapped to H37Rv Rv3653 YP_001289611.1 Mapped to H37Rv Rv3654c YP_001289612.1 Mapped to H37Rv Rv3655c YP_001289613.1 Mapped to H37Rv Rv3656c YP_001289614.1 Mapped to H37Rv Rv3657c YP_001289615.1 Mapped to H37Rv Rv3658c YP_001289616.1 Mapped to H37Rv Rv3659c YP_001289617.1 Mapped to H37Rv Rv3660c YP_001289618.1 Mapped to H37Rv Rv3661 YP_001289619.1 Mapped to H37Rv Rv3662c YP_001289620.1 Mapped to H37Rv Rv3663c YP_001289621.1 Mapped to H37Rv Rv3664c YP_001289622.1 Mapped to H37Rv Rv3665c YP_001289623.1 Mapped to H37Rv Rv3666c YP_001289624.1 Mapped to H37Rv Rv3666c YP_001289625.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001289626.1 Mapped to H37Rv Rv3668c YP_001289627.1 Mapped to H37Rv Rv3669 YP_001289628.1 Mapped to H37Rv Rv3670 YP_001289629.1 Mapped to H37Rv Rv3671c YP_001289630.1 Mapped to H37Rv Rv3672c YP_001289631.1 Mapped to H37Rv Rv3673c YP_001289632.1 Mapped to H37Rv Rv3674c YP_001289633.1 Mapped to H37Rv Rv3675 YP_001289634.1 Mapped to H37Rv Rv3676 YP_001289635.1 Mapped to H37Rv Rv3677c YP_001289636.1 Mapped to H37Rv Rv3678c YP_001289637.1 Mapped to H37Rv Rv3679 YP_001289638.1 Mapped to H37Rv Rv3680 YP_001289639.1 Mapped to H37Rv Rv3681c YP_001289640.1 Mapped to H37Rv Rv3682 YP_001289641.1 Mapped to H37Rv Rv3683 YP_001289642.1 Mapped to H37Rv Rv3684 YP_001289643.1 Mapped to H37Rv Rv3685c YP_001289644.1 Mapped to H37Rv Rv3686c YP_001289645.1 Mapped to H37Rv Rv3687c YP_001289646.1 Mapped to H37Rv Rv3688c YP_001289647.1 Mapped to H37Rv Rv3689 YP_001289648.1 Mapped to H37Rv Rv3690 YP_001289649.1 Mapped to H37Rv Rv3691 YP_001289650.1 Mapped to H37Rv Rv3692 YP_001289651.1 Mapped to H37Rv Rv3693 YP_001289652.1 Mapped to H37Rv Rv3694c YP_001289653.1 Mapped to H37Rv Rv3695 YP_001289654.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001289655.1 Mapped to H37Rv Rv3697c YP_001289656.1 Mapped to H37Rv Rv3698 YP_001289657.1 Mapped to H37Rv Rv3699 YP_001289658.1 Mapped to H37Rv Rv3700c YP_001289659.1 Mapped to H37Rv Rv3701c YP_001289660.1 Mapped to H37Rv Rv3702c YP_001289661.1 Mapped to H37Rv Rv3703c YP_001289662.1 Mapped to H37Rv Rv3704c YP_001289663.1 Mapped to H37Rv Rv3705c YP_001289664.1 Mapped to H37Rv Rv3705A YP_001289665.1 Mapped to H37Rv Rv3706c YP_001289666.1 Mapped to H37Rv Rv3707c YP_001289667.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001289668.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001289669.1 Mapped to H37Rv Rv3710 YP_001289670.1 3'-5' exonuclease of DNA polymerase III YP_001289671.1 Mapped to H37Rv Rv3712 YP_001289672.1 Mapped to H37Rv Rv3713 YP_001289673.1 Mapped to H37Rv Rv3714c YP_001289674.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001289675.1 Mapped to H37Rv Rv3716c YP_001289676.1 Mapped to H37Rv Rv3717 YP_001289677.1 Mapped to H37Rv Rv3718c YP_001289678.1 Mapped to H37Rv Rv3719 YP_001289679.1 Mapped to H37Rv Rv3720 YP_001289680.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001289681.1 Mapped to H37Rv Rv3722c YP_001289682.1 Mapped to H37Rv Rv3723 YP_001289683.1 Mapped to H37Rv Rv3724B YP_001289684.1 Mapped to H37Rv Rv3725 YP_001289685.1 Mapped to H37Rv Rv3726 YP_001289686.1 Mapped to H37Rv Rv3727 YP_001289687.1 Mapped to H37Rv Rv3728 YP_001289688.1 Mapped to H37Rv Rv3729 YP_001289689.1 Mapped to H37Rv Rv3730c YP_001289690.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth YP_001289691.1 Mapped to H37Rv Rv3732 YP_001289692.1 Mapped to H37Rv Rv3733c YP_001289693.1 Mapped to H37Rv Rv3734c YP_001289694.1 Mapped to H37Rv Rv3735 YP_001289695.1 Mapped to H37Rv Rv3736 YP_001289696.1 Mapped to H37Rv Rv3737 YP_001289697.1 Mapped to H37Rv Rv3738c YP_001289698.1 Mapped to H37Rv Rv3739c YP_001289699.1 Mapped to H37Rv Rv3740c YP_001289700.1 Mapped to H37Rv Rv3741c YP_001289701.1 Mapped to H37Rv Rv3742c YP_001289702.1 Mapped to H37Rv Rv3743c YP_001289703.1 Mapped to H37Rv Rv3744 YP_001289704.1 Mapped to H37Rv Rv3745c YP_001289705.1 Mapped to H37Rv Rv3746c YP_001289706.1 Mapped to H37Rv Rv3747 YP_001289707.1 Mapped to H37Rv Rv3748 YP_001289708.1 Mapped to H37Rv Rv3749c YP_001289709.1 Mapped to H37Rv Rv3750c YP_001289710.1 Mapped to H37Rv Rv3751 YP_001289711.1 Mapped to H37Rv Rv3752c YP_001289712.1 Mapped to H37Rv Rv3753c YP_001289713.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_001289714.1 Mapped to H37Rv Rv3755c YP_001289715.1 Mapped to H37Rv Rv3756c YP_001289716.1 Mapped to H37Rv Rv3757c YP_001289717.1 Mapped to H37Rv Rv3758c YP_001289718.1 Mapped to H37Rv Rv3759c YP_001289719.1 Mapped to H37Rv Rv3760 YP_001289720.1 Mapped to H37Rv Rv3761c YP_001289721.1 Mapped to H37Rv Rv3762c YP_001289722.1 Mapped to H37Rv Rv3763 YP_001289723.1 Mapped to H37Rv Rv3764c YP_001289724.1 Mapped to H37Rv Rv3765c YP_001289725.1 Mapped to H37Rv Rv3766 YP_001289726.1 Mapped to H37Rv Rv3767c YP_001289727.1 Mapped to H37Rv Rv3768 YP_001289728.1 Mapped to H37Rv Rv3769 YP_001289729.1 Mapped to H37Rv Rv3770c YP_001289730.1 Mapped to H37Rv Rv3770A YP_001289731.1 Mapped to H37Rv Rv3770B YP_001289732.1 Mapped to H37Rv Rv3771c YP_001289733.1 Mapped to H37Rv Rv3772 YP_001289734.1 Mapped to H37Rv Rv3773c YP_001289735.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001289736.1 Mapped to H37Rv Rv3775 YP_001289737.1 Mapped to H37Rv Rv3776 YP_001289738.1 Mapped to H37Rv Rv3777 YP_001289739.1 Mapped to H37Rv Rv3778c YP_001289740.1 Mapped to H37Rv Rv3779 YP_001289741.1 Mapped to H37Rv Rv3780 YP_001289742.1 Mapped to H37Rv Rv3781 YP_001289743.1 Mapped to H37Rv Rv3782 YP_001289744.1 Mapped to H37Rv Rv3783 YP_001289745.1 Mapped to H37Rv Rv3784 YP_001289746.1 Mapped to H37Rv Rv3785 YP_001289747.1 Mapped to H37Rv Rv3786c YP_001289748.1 Mapped to H37Rv Rv3787c YP_001289749.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001289750.1 Mapped to H37Rv Rv3789 YP_001289751.1 Mapped to H37Rv Rv3790 YP_001289752.1 Mapped to H37Rv Rv3791 YP_001289753.1 Mapped to H37Rv Rv3792 YP_001289754.1 Mapped to H37Rv Rv3793 YP_001289755.1 Mapped to H37Rv Rv3794 YP_001289756.1 Mapped to H37Rv Rv3795 YP_001289757.1 Mapped to H37Rv Rv3796 YP_001289758.1 Mapped to H37Rv Rv3797 YP_001289759.1 Mapped to H37Rv Rv3798 YP_001289760.1 Mapped to H37Rv Rv3799c YP_001289761.1 Mapped to H37Rv Rv3800c YP_001289762.1 activates fatty acids by binding to coenzyme A YP_001289763.1 Mapped to H37Rv Rv3802c YP_001289764.1 Mapped to H37Rv Rv3803c YP_001289765.1 Mapped to H37Rv Rv3804c YP_001289766.1 Mapped to H37Rv Rv3805c YP_001289767.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate YP_001289768.1 Mapped to H37Rv Rv3807c YP_001289769.1 Mapped to H37Rv Rv3808c YP_001289770.1 Mapped to H37Rv Rv3809c YP_001289771.1 Mapped to H37Rv Rv3810 YP_001289772.1 Mapped to H37Rv Rv3811 YP_001289773.1 Mapped to H37Rv Rv3812 YP_001289774.1 Mapped to H37Rv Rv3813c YP_001289775.1 Mapped to H37Rv Rv3814c YP_001289776.1 Mapped to H37Rv Rv3815c YP_001289777.1 Mapped to H37Rv Rv3816c YP_001289778.1 Mapped to H37Rv Rv3817 YP_001289779.1 Mapped to H37Rv Rv3818 YP_001289780.1 Mapped to H37Rv Rv3819 YP_001289781.1 Mapped to H37Rv Rv3820c YP_001289782.1 Mapped to H37Rv Rv3821 YP_001289783.1 Mapped to H37Rv Rv3822 YP_001289784.1 Mapped to H37Rv Rv3823c YP_001289785.1 Mapped to H37Rv Rv3824c YP_001289786.1 Mapped to H37Rv Rv3825c YP_001289787.1 activates fatty acids by binding to coenzyme A YP_001289788.1 Mapped to H37Rv Rv3827c YP_001289789.1 Mapped to H37Rv Rv3828c YP_001289790.1 Mapped to H37Rv Rv3829c YP_001289791.1 Mapped to H37Rv Rv3830c YP_001289792.1 Mapped to H37Rv Rv3831 YP_001289793.1 Mapped to H37Rv Rv3832c YP_001289794.1 Mapped to H37Rv Rv3833 YP_001289795.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001289796.1 Mapped to H37Rv Rv3835 YP_001289797.1 Mapped to H37Rv Rv3836 YP_001289798.1 Mapped to H37Rv Rv3837c YP_001289799.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001289800.1 Mapped to H37Rv Rv3839 YP_001289801.1 Mapped to H37Rv Rv3840 YP_001289802.1 Mapped to H37Rv Rv3841 YP_001289803.1 Mapped to H37Rv Rv3842c YP_001289804.1 Mapped to H37Rv Rv3843c YP_001289805.1 Mapped to H37Rv Rv3843c YP_001289807.1 Mapped to H37Rv Rv3844 YP_001289808.1 Mapped to H37Rv Rv3845 YP_001289809.1 Mapped to H37Rv Rv3846 YP_001289810.1 Mapped to H37Rv Rv3847 YP_001289811.1 Mapped to H37Rv Rv3848 YP_001289812.1 Mapped to H37Rv Rv3849 YP_001289813.1 Mapped to H37Rv Rv3850 YP_001289814.1 Mapped to H37Rv Rv3851 YP_001289815.1 Mapped to H37Rv Rv3852 YP_001289816.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001289817.1 Mapped to H37Rv Rv3854c YP_001289818.1 Mapped to H37Rv Rv3855 YP_001289819.1 Mapped to H37Rv Rv3856c YP_001289820.1 Mapped to H37Rv Rv3857c YP_001289821.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001289822.1 Mapped to H37Rv Rv3859c YP_001289823.1 Mapped to H37Rv Rv3860 YP_001289824.1 Mapped to H37Rv Rv3862c YP_001289825.1 Mapped to H37Rv Rv3863 YP_001289826.1 Mapped to H37Rv Rv3864 YP_001289827.1 Mapped to H37Rv Rv3865 YP_001289828.1 Mapped to H37Rv Rv3866 YP_001289829.1 Mapped to H37Rv Rv3867 YP_001289830.1 Mapped to H37Rv Rv3868 YP_001289831.1 Mapped to H37Rv Rv3869 YP_001289832.1 Mapped to H37Rv Rv3870 YP_001289833.1 Mapped to H37Rv Rv3871 YP_001289834.1 Mapped to H37Rv Rv3872 YP_001289835.1 Mapped to H37Rv Rv3873 YP_001289836.1 Mapped to H37Rv Rv3874 YP_001289837.1 Mapped to H37Rv Rv3875 YP_001289838.1 Mapped to H37Rv Rv3876 YP_001289839.1 Mapped to H37Rv Rv3877 YP_001289840.1 Mapped to H37Rv Rv3878 YP_001289841.1 Mapped to H37Rv Rv3879c YP_001289842.1 Mapped to H37Rv Rv3880c YP_001289843.1 Mapped to H37Rv Rv3881c YP_001289844.1 Mapped to H37Rv Rv3882c YP_001289845.1 Mapped to H37Rv Rv3883c YP_001289846.1 Mapped to H37Rv Rv3884c YP_001289847.1 Mapped to H37Rv Rv3885c YP_001289848.1 Mapped to H37Rv Rv3886c YP_001289849.1 Mapped to H37Rv Rv3887c YP_001289850.1 Mapped to H37Rv Rv3888c YP_001289851.1 Mapped to H37Rv Rv3889c YP_001289852.1 Mapped to H37Rv Rv3890c YP_001289853.1 Mapped to H37Rv Rv3891c YP_001289854.1 Mapped to H37Rv Rv3892c YP_001289855.1 Mapped to H37Rv Rv3893c YP_001289856.1 Mapped to H37Rv Rv3894c YP_001289857.1 Mapped to H37Rv Rv3895c YP_001289858.1 Mapped to H37Rv Rv3896c YP_001289859.1 Mapped to H37Rv Rv3897c YP_001289860.1 Mapped to H37Rv Rv3898c YP_001289861.1 Mapped to H37Rv Rv3899c YP_001289862.1 Mapped to H37Rv Rv3900c YP_001289863.1 Mapped to H37Rv Rv3901c YP_001289864.1 Mapped to H37Rv Rv3902c YP_001289865.1 Mapped to H37Rv Rv3903c YP_001289866.1 Mapped to H37Rv Rv3904c YP_001289867.1 Mapped to H37Rv Rv3905c YP_001289868.1 Mapped to H37Rv Rv3906c YP_001289869.1 Mapped to H37Rv Rv3907c YP_001289870.1 Mapped to H37Rv Rv3908 YP_001289871.1 Mapped to H37Rv Rv3909 YP_001289872.1 Mapped to H37Rv Rv3910 YP_001289873.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase YP_001289874.1 Mapped to H37Rv Rv3912 YP_001289875.1 Mapped to H37Rv Rv3913 YP_001289876.1 Mapped to H37Rv Rv3914 YP_001289877.1 Mapped to H37Rv Rv3915 YP_001289878.1 Mapped to H37Rv Rv3916c YP_001289879.1 Mapped to H37Rv Rv3917c YP_001289880.1 Mapped to H37Rv Rv3918c YP_001289881.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001289882.1 Mapped to H37Rv Rv3920c YP_001289883.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001289884.1 Mapped to H37Rv Rv3922c YP_001289885.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001289886.1 in Escherichia coli transcription of this gene is enhanced by polyamines